CDW54_RS10885 3f1c56e60e1c4ad4807d254dc38ee963 768 Gene3D G3DSA:3.30.56.50 4 46 6.8E-13 T 28-03-2018 CDW54_RS10885 3f1c56e60e1c4ad4807d254dc38ee963 768 Gene3D G3DSA:3.30.56.50 193 234 7.8E-10 T 28-03-2018 CDW54_RS10885 3f1c56e60e1c4ad4807d254dc38ee963 768 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 767 17.179 T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CDW54_RS10885 3f1c56e60e1c4ad4807d254dc38ee963 768 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 1 51 1.6E-14 T 28-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal CDW54_RS10885 3f1c56e60e1c4ad4807d254dc38ee963 768 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 190 239 2.2E-13 T 28-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal CDW54_RS10885 3f1c56e60e1c4ad4807d254dc38ee963 768 ProSitePatterns PS01176 Initiation factor 2 signature. 720 742 - T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CDW54_RS10885 3f1c56e60e1c4ad4807d254dc38ee963 768 Gene3D G3DSA:3.40.50.10050 567 648 3.3E-29 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CDW54_RS10885 3f1c56e60e1c4ad4807d254dc38ee963 768 SUPERFAMILY SSF52540 262 441 7.83E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS10885 3f1c56e60e1c4ad4807d254dc38ee963 768 Gene3D G3DSA:2.40.30.10 437 533 4.2E-14 T 28-03-2018 CDW54_RS10885 3f1c56e60e1c4ad4807d254dc38ee963 768 Pfam PF00009 Elongation factor Tu GTP binding domain 274 430 1.3E-34 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDW54_RS10885 3f1c56e60e1c4ad4807d254dc38ee963 768 Gene3D G3DSA:2.40.30.10 670 768 3.3E-27 T 28-03-2018 CDW54_RS10885 3f1c56e60e1c4ad4807d254dc38ee963 768 Gene3D G3DSA:3.40.50.300 264 436 4.3E-41 T 28-03-2018 CDW54_RS10885 3f1c56e60e1c4ad4807d254dc38ee963 768 SUPERFAMILY SSF52156 548 676 1.44E-38 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CDW54_RS10885 3f1c56e60e1c4ad4807d254dc38ee963 768 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 184 767 7.4E-258 T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CDW54_RS10885 3f1c56e60e1c4ad4807d254dc38ee963 768 Pfam PF11987 Translation-initiation factor 2 555 659 5.0E-38 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CDW54_RS10885 3f1c56e60e1c4ad4807d254dc38ee963 768 SUPERFAMILY SSF50447 442 524 3.09E-24 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CDW54_RS10885 3f1c56e60e1c4ad4807d254dc38ee963 768 SUPERFAMILY SSF50447 670 766 1.39E-31 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CDW54_RS10885 3f1c56e60e1c4ad4807d254dc38ee963 768 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 271 428 4.5E-38 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CDW54_RS01030 283ae99d2636e9e48937dd855ef6d7ca 210 Gene3D G3DSA:1.10.530.10 29 185 6.6E-15 T 28-03-2018 CDW54_RS01030 283ae99d2636e9e48937dd855ef6d7ca 210 SUPERFAMILY SSF53955 41 156 3.09E-12 T 28-03-2018 IPR023346 Lysozyme-like domain CDW54_RS01030 283ae99d2636e9e48937dd855ef6d7ca 210 Pfam PF13702 Lysozyme-like 36 198 3.5E-54 T 28-03-2018 CDW54_RS01610 aa081892fac828e7a6ec6c2446322694 88 PRINTS PR00107 Phosphocarrier protein signature 13 29 2.3E-27 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CDW54_RS01610 aa081892fac828e7a6ec6c2446322694 88 PRINTS PR00107 Phosphocarrier protein signature 53 70 2.3E-27 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CDW54_RS01610 aa081892fac828e7a6ec6c2446322694 88 PRINTS PR00107 Phosphocarrier protein signature 38 53 2.3E-27 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CDW54_RS01610 aa081892fac828e7a6ec6c2446322694 88 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 28-03-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site CDW54_RS01610 aa081892fac828e7a6ec6c2446322694 88 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 81 1.3E-32 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CDW54_RS01610 aa081892fac828e7a6ec6c2446322694 88 Pfam PF00381 PTS HPr component phosphorylation site 3 82 3.3E-30 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CDW54_RS01610 aa081892fac828e7a6ec6c2446322694 88 Gene3D G3DSA:3.30.1340.10 1 88 1.6E-32 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CDW54_RS01610 aa081892fac828e7a6ec6c2446322694 88 SUPERFAMILY SSF55594 1 83 1.44E-28 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CDW54_RS01610 aa081892fac828e7a6ec6c2446322694 88 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 28-03-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site CDW54_RS07180 ce6f008eb484705d511488538c155e3c 850 Pfam PF00122 E1-E2 ATPase 112 303 1.3E-50 T 28-03-2018 CDW54_RS07180 ce6f008eb484705d511488538c155e3c 850 SUPERFAMILY SSF81653 113 220 9.81E-29 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CDW54_RS07180 ce6f008eb484705d511488538c155e3c 850 Gene3D G3DSA:1.20.1110.10 493 848 3.6E-81 T 28-03-2018 CDW54_RS07180 ce6f008eb484705d511488538c155e3c 850 SMART SM00831 2 75 2.4E-23 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CDW54_RS07180 ce6f008eb484705d511488538c155e3c 850 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 325 331 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CDW54_RS07180 ce6f008eb484705d511488538c155e3c 850 SUPERFAMILY SSF81665 223 317 3.14E-106 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CDW54_RS07180 ce6f008eb484705d511488538c155e3c 850 SUPERFAMILY SSF81665 1 113 3.14E-106 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CDW54_RS07180 ce6f008eb484705d511488538c155e3c 850 SUPERFAMILY SSF81665 631 839 3.14E-106 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CDW54_RS07180 ce6f008eb484705d511488538c155e3c 850 Pfam PF00702 haloacid dehalogenase-like hydrolase 319 595 2.1E-26 T 28-03-2018 CDW54_RS07180 ce6f008eb484705d511488538c155e3c 850 SUPERFAMILY SSF56784 321 341 3.36E-59 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS07180 ce6f008eb484705d511488538c155e3c 850 SUPERFAMILY SSF56784 437 685 3.36E-59 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS07180 ce6f008eb484705d511488538c155e3c 850 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 205 352 9.8E-25 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDW54_RS07180 ce6f008eb484705d511488538c155e3c 850 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 81 191 2.5E-18 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDW54_RS07180 ce6f008eb484705d511488538c155e3c 850 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 554 670 4.8E-33 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDW54_RS07180 ce6f008eb484705d511488538c155e3c 850 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 366 526 2.0E-18 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDW54_RS07180 ce6f008eb484705d511488538c155e3c 850 Gene3D G3DSA:3.40.1110.10 287 487 6.8E-41 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CDW54_RS07180 ce6f008eb484705d511488538c155e3c 850 Pfam PF00690 Cation transporter/ATPase, N-terminus 3 69 4.0E-16 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CDW54_RS07180 ce6f008eb484705d511488538c155e3c 850 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 440 458 1.4E-17 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDW54_RS07180 ce6f008eb484705d511488538c155e3c 850 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 613 638 1.4E-17 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDW54_RS07180 ce6f008eb484705d511488538c155e3c 850 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 581 597 1.4E-17 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDW54_RS07180 ce6f008eb484705d511488538c155e3c 850 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 553 569 1.4E-17 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDW54_RS07180 ce6f008eb484705d511488538c155e3c 850 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 581 600 5.3E-38 T 28-03-2018 CDW54_RS07180 ce6f008eb484705d511488538c155e3c 850 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 323 337 5.3E-38 T 28-03-2018 CDW54_RS07180 ce6f008eb484705d511488538c155e3c 850 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 480 491 5.3E-38 T 28-03-2018 CDW54_RS07180 ce6f008eb484705d511488538c155e3c 850 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 502 512 5.3E-38 T 28-03-2018 CDW54_RS07180 ce6f008eb484705d511488538c155e3c 850 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 160 174 5.3E-38 T 28-03-2018 CDW54_RS07180 ce6f008eb484705d511488538c155e3c 850 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 605 617 5.3E-38 T 28-03-2018 CDW54_RS07180 ce6f008eb484705d511488538c155e3c 850 Gene3D G3DSA:2.70.150.10 11 223 2.1E-43 T 28-03-2018 CDW54_RS07180 ce6f008eb484705d511488538c155e3c 850 Pfam PF00689 Cation transporting ATPase, C-terminus 665 831 1.5E-33 T 28-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 CDW54_RS10910 404aa760afc97c98f0cdfb8295e235b0 313 PIRSF PIRSF004491 1 313 8.6E-97 T 28-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CDW54_RS10910 404aa760afc97c98f0cdfb8295e235b0 313 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 21 311 1.2E-80 T 28-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CDW54_RS10910 404aa760afc97c98f0cdfb8295e235b0 313 Gene3D G3DSA:3.40.50.620 2 182 1.5E-36 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDW54_RS10910 404aa760afc97c98f0cdfb8295e235b0 313 SMART SM00904 186 311 5.3E-52 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CDW54_RS10910 404aa760afc97c98f0cdfb8295e235b0 313 SUPERFAMILY SSF52374 20 179 2.28E-25 T 28-03-2018 CDW54_RS10910 404aa760afc97c98f0cdfb8295e235b0 313 Gene3D G3DSA:2.40.30.30 183 313 7.8E-39 T 28-03-2018 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 CDW54_RS10910 404aa760afc97c98f0cdfb8295e235b0 313 SUPERFAMILY SSF82114 177 312 2.62E-43 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CDW54_RS10910 404aa760afc97c98f0cdfb8295e235b0 313 Pfam PF06574 FAD synthetase 18 170 2.2E-44 T 28-03-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CDW54_RS10910 404aa760afc97c98f0cdfb8295e235b0 313 Pfam PF01687 Riboflavin kinase 187 309 4.4E-33 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CDW54_RS06670 727631c9054b7fbb947d2a51dca7f60f 879 Pfam PF00122 E1-E2 ATPase 117 310 2.7E-53 T 28-03-2018 CDW54_RS06670 727631c9054b7fbb947d2a51dca7f60f 879 Pfam PF00689 Cation transporting ATPase, C-terminus 693 869 2.5E-42 T 28-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 CDW54_RS06670 727631c9054b7fbb947d2a51dca7f60f 879 Pfam PF00702 haloacid dehalogenase-like hydrolase 327 621 1.9E-27 T 28-03-2018 CDW54_RS06670 727631c9054b7fbb947d2a51dca7f60f 879 Gene3D G3DSA:1.20.1110.10 629 872 1.9E-60 T 28-03-2018 CDW54_RS06670 727631c9054b7fbb947d2a51dca7f60f 879 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 89 408 2.3E-45 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDW54_RS06670 727631c9054b7fbb947d2a51dca7f60f 879 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 578 695 4.3E-33 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDW54_RS06670 727631c9054b7fbb947d2a51dca7f60f 879 SMART SM00831 2 76 3.8E-19 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CDW54_RS06670 727631c9054b7fbb947d2a51dca7f60f 879 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 330 344 4.0E-40 T 28-03-2018 CDW54_RS06670 727631c9054b7fbb947d2a51dca7f60f 879 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 528 538 4.0E-40 T 28-03-2018 CDW54_RS06670 727631c9054b7fbb947d2a51dca7f60f 879 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 608 627 4.0E-40 T 28-03-2018 CDW54_RS06670 727631c9054b7fbb947d2a51dca7f60f 879 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 632 644 4.0E-40 T 28-03-2018 CDW54_RS06670 727631c9054b7fbb947d2a51dca7f60f 879 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 506 517 4.0E-40 T 28-03-2018 CDW54_RS06670 727631c9054b7fbb947d2a51dca7f60f 879 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 167 181 4.0E-40 T 28-03-2018 CDW54_RS06670 727631c9054b7fbb947d2a51dca7f60f 879 Gene3D G3DSA:2.70.150.10 11 231 4.7E-48 T 28-03-2018 CDW54_RS06670 727631c9054b7fbb947d2a51dca7f60f 879 SUPERFAMILY SSF81653 119 229 5.49E-30 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CDW54_RS06670 727631c9054b7fbb947d2a51dca7f60f 879 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 332 338 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CDW54_RS06670 727631c9054b7fbb947d2a51dca7f60f 879 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 640 665 2.8E-18 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDW54_RS06670 727631c9054b7fbb947d2a51dca7f60f 879 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 608 624 2.8E-18 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDW54_RS06670 727631c9054b7fbb947d2a51dca7f60f 879 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 580 596 2.8E-18 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDW54_RS06670 727631c9054b7fbb947d2a51dca7f60f 879 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 464 482 2.8E-18 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDW54_RS06670 727631c9054b7fbb947d2a51dca7f60f 879 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 785 806 2.8E-18 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDW54_RS06670 727631c9054b7fbb947d2a51dca7f60f 879 Gene3D G3DSA:3.40.50.1000 503 628 5.0E-19 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS06670 727631c9054b7fbb947d2a51dca7f60f 879 SUPERFAMILY SSF81665 231 324 3.66E-121 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CDW54_RS06670 727631c9054b7fbb947d2a51dca7f60f 879 SUPERFAMILY SSF81665 658 871 3.66E-121 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CDW54_RS06670 727631c9054b7fbb947d2a51dca7f60f 879 SUPERFAMILY SSF81665 2 120 3.66E-121 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CDW54_RS06670 727631c9054b7fbb947d2a51dca7f60f 879 SUPERFAMILY SSF81660 337 510 4.58E-38 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CDW54_RS06670 727631c9054b7fbb947d2a51dca7f60f 879 SUPERFAMILY SSF56784 461 711 2.88E-59 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS06670 727631c9054b7fbb947d2a51dca7f60f 879 SUPERFAMILY SSF56784 328 348 2.88E-59 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS06670 727631c9054b7fbb947d2a51dca7f60f 879 Pfam PF00690 Cation transporter/ATPase, N-terminus 4 71 1.6E-17 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CDW54_RS06670 727631c9054b7fbb947d2a51dca7f60f 879 Gene3D G3DSA:3.40.1110.10 291 502 1.2E-46 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CDW54_RS08440 e276412c689c9b4a1181c1c82cd87f15 507 Pfam PF04586 Caudovirus prohead serine protease 30 183 1.9E-46 T 28-03-2018 IPR006433 Prohead protease CDW54_RS08440 e276412c689c9b4a1181c1c82cd87f15 507 SUPERFAMILY SSF56563 239 500 2.75E-42 T 28-03-2018 CDW54_RS08440 e276412c689c9b4a1181c1c82cd87f15 507 Gene3D G3DSA:3.20.16.10 33 241 1.3E-23 T 28-03-2018 IPR035443 Herpesvirus/Caudovirus protease domain CDW54_RS08440 e276412c689c9b4a1181c1c82cd87f15 507 TIGRFAM TIGR01543 proheadase_HK97: phage prohead protease, HK97 family 36 177 2.8E-27 T 28-03-2018 IPR006433 Prohead protease CDW54_RS08440 e276412c689c9b4a1181c1c82cd87f15 507 Gene3D G3DSA:3.30.2320.10 357 469 5.9E-25 T 28-03-2018 CDW54_RS08440 e276412c689c9b4a1181c1c82cd87f15 507 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 188 499 1.2E-63 T 28-03-2018 IPR024455 Phage capsid CDW54_RS08440 e276412c689c9b4a1181c1c82cd87f15 507 Pfam PF05065 Phage capsid family 245 497 3.2E-27 T 28-03-2018 IPR024455 Phage capsid CDW54_RS07900 358e0c61a85cd20619ece3ae9118c27f 419 Gene3D G3DSA:2.40.37.10 270 418 8.0E-42 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CDW54_RS07900 358e0c61a85cd20619ece3ae9118c27f 419 SUPERFAMILY SSF50621 255 414 2.72E-52 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CDW54_RS07900 358e0c61a85cd20619ece3ae9118c27f 419 SUPERFAMILY SSF51419 20 283 1.21E-69 T 28-03-2018 IPR029066 PLP-binding barrel CDW54_RS07900 358e0c61a85cd20619ece3ae9118c27f 419 Gene3D G3DSA:3.20.20.10 27 269 8.3E-54 T 28-03-2018 IPR029066 PLP-binding barrel CDW54_RS07900 358e0c61a85cd20619ece3ae9118c27f 419 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 22 371 7.9E-20 T 28-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 CDW54_RS07900 358e0c61a85cd20619ece3ae9118c27f 419 PRINTS PR01181 Diaminopimelate decarboxylase signature 70 87 1.8E-27 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CDW54_RS07900 358e0c61a85cd20619ece3ae9118c27f 419 PRINTS PR01181 Diaminopimelate decarboxylase signature 381 403 1.8E-27 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CDW54_RS07900 358e0c61a85cd20619ece3ae9118c27f 419 PRINTS PR01181 Diaminopimelate decarboxylase signature 159 168 1.8E-27 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CDW54_RS07900 358e0c61a85cd20619ece3ae9118c27f 419 PRINTS PR01181 Diaminopimelate decarboxylase signature 299 317 1.8E-27 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CDW54_RS07900 358e0c61a85cd20619ece3ae9118c27f 419 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 2 413 7.2E-138 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CDW54_RS07900 358e0c61a85cd20619ece3ae9118c27f 419 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 36 281 2.2E-51 T 28-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 CDW54_RS07900 358e0c61a85cd20619ece3ae9118c27f 419 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 52 70 - T 28-03-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site CDW54_RS07900 358e0c61a85cd20619ece3ae9118c27f 419 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 52 70 1.4E-18 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CDW54_RS07900 358e0c61a85cd20619ece3ae9118c27f 419 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 187 200 1.4E-18 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CDW54_RS07900 358e0c61a85cd20619ece3ae9118c27f 419 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 271 290 1.4E-18 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CDW54_RS07900 358e0c61a85cd20619ece3ae9118c27f 419 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 72 84 1.4E-18 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CDW54_RS07900 358e0c61a85cd20619ece3ae9118c27f 419 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 371 384 1.4E-18 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CDW54_RS07900 358e0c61a85cd20619ece3ae9118c27f 419 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 8 414 38.49 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CDW54_RS08545 063d1c206aee05c33c0ae5fae5ce33d8 473 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 438 468 1.2E-6 T 28-03-2018 CDW54_RS08545 063d1c206aee05c33c0ae5fae5ce33d8 473 Gene3D G3DSA:2.60.40.740 198 321 2.1E-14 T 28-03-2018 CDW54_RS08545 063d1c206aee05c33c0ae5fae5ce33d8 473 Gene3D G3DSA:2.60.40.810 19 197 3.8E-5 T 28-03-2018 CDW54_RS08545 063d1c206aee05c33c0ae5fae5ce33d8 473 Gene3D G3DSA:2.60.40.810 322 449 1.1E-19 T 28-03-2018 CDW54_RS08545 063d1c206aee05c33c0ae5fae5ce33d8 473 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 188 307 6.6E-20 T 28-03-2018 IPR026466 Fimbrial isopeptide formation D2 domain CDW54_RS08545 063d1c206aee05c33c0ae5fae5ce33d8 473 Pfam PF16555 Gram-positive pilin subunit D1, N-terminal 24 184 5.0E-13 T 28-03-2018 IPR032364 Gram-positive pilin subunit D1, N-terminal CDW54_RS08545 063d1c206aee05c33c0ae5fae5ce33d8 473 SUPERFAMILY SSF49478 334 411 5.89E-5 T 28-03-2018 CDW54_RS08545 063d1c206aee05c33c0ae5fae5ce33d8 473 Pfam PF16569 Gram-positive pilin backbone subunit 2, Cna-B-like domain 203 307 4.7E-9 T 28-03-2018 IPR032334 Gram-positive pilin backbone subunit 2, Cna-B-like domain CDW54_RS03020 cc0672bfc4865eef426466904889b5ff 559 Hamap MF_01491 Ribonuclease J [rnj]. 1 552 39.425 T 28-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CDW54_RS03020 cc0672bfc4865eef426466904889b5ff 559 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 4 550 4.2E-166 T 28-03-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 CDW54_RS03020 cc0672bfc4865eef426466904889b5ff 559 Gene3D G3DSA:3.60.15.10 1 445 1.7E-59 T 28-03-2018 IPR001279 Metallo-beta-lactamase CDW54_RS03020 cc0672bfc4865eef426466904889b5ff 559 Pfam PF00753 Metallo-beta-lactamase superfamily 16 163 9.0E-13 T 28-03-2018 IPR001279 Metallo-beta-lactamase CDW54_RS03020 cc0672bfc4865eef426466904889b5ff 559 SMART SM00849 16 216 2.5E-22 T 28-03-2018 IPR001279 Metallo-beta-lactamase CDW54_RS03020 cc0672bfc4865eef426466904889b5ff 559 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 358 401 1.5E-9 T 28-03-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain CDW54_RS03020 cc0672bfc4865eef426466904889b5ff 559 SUPERFAMILY SSF56281 4 420 4.19E-79 T 28-03-2018 IPR001279 Metallo-beta-lactamase CDW54_RS03020 cc0672bfc4865eef426466904889b5ff 559 PIRSF PIRSF004803 1 552 9.1E-184 T 28-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CDW54_RS03905 c09890312663fa0d071b51fc2d80320f 310 Pfam PF00005 ABC transporter 18 161 2.0E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS03905 c09890312663fa0d071b51fc2d80320f 310 SUPERFAMILY SSF52540 2 222 1.46E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS03905 c09890312663fa0d071b51fc2d80320f 310 SMART SM00382 27 210 1.2E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS03905 c09890312663fa0d071b51fc2d80320f 310 Gene3D G3DSA:3.40.50.300 1 267 2.4E-65 T 28-03-2018 CDW54_RS01540 96254ea4c2a5c6b8706803af127d0184 139 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 1 138 1.3E-59 T 28-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CDW54_RS01540 96254ea4c2a5c6b8706803af127d0184 139 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 1 139 33.086 T 28-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CDW54_RS01540 96254ea4c2a5c6b8706803af127d0184 139 SUPERFAMILY SSF54637 3 138 4.17E-49 T 28-03-2018 IPR029069 HotDog domain CDW54_RS01540 96254ea4c2a5c6b8706803af127d0184 139 Gene3D G3DSA:3.10.129.10 1 139 1.3E-54 T 28-03-2018 CDW54_RS01540 96254ea4c2a5c6b8706803af127d0184 139 Pfam PF07977 FabA-like domain 10 133 1.2E-39 T 28-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CDW54_RS01500 b3aaa4ab4acb7977fd1c6f9dd695504d 197 SMART SM00471 25 152 3.3E-7 T 28-03-2018 IPR003607 HD/PDEase domain CDW54_RS01500 b3aaa4ab4acb7977fd1c6f9dd695504d 197 SUPERFAMILY SSF109604 7 196 9.11E-37 T 28-03-2018 CDW54_RS01500 b3aaa4ab4acb7977fd1c6f9dd695504d 197 TIGRFAM TIGR00488 TIGR00488: putative HD superfamily hydrolase 22 192 2.0E-50 T 28-03-2018 IPR005249 Conserved hypothetical protein CHP00488 CDW54_RS01500 b3aaa4ab4acb7977fd1c6f9dd695504d 197 Pfam PF01966 HD domain 29 141 3.3E-12 T 28-03-2018 IPR006674 HD domain CDW54_RS01500 b3aaa4ab4acb7977fd1c6f9dd695504d 197 Gene3D G3DSA:1.10.3210.10 10 197 1.5E-27 T 28-03-2018 CDW54_RS05970 c68fae5ef9202553ad1a8a120568ef2b 122 Gene3D G3DSA:2.40.150.20 1 122 1.7E-49 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CDW54_RS05970 c68fae5ef9202553ad1a8a120568ef2b 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 26.318 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CDW54_RS05970 c68fae5ef9202553ad1a8a120568ef2b 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 28-03-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS05970 c68fae5ef9202553ad1a8a120568ef2b 122 SMART SM01374 1 122 1.6E-80 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CDW54_RS05970 c68fae5ef9202553ad1a8a120568ef2b 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 1.5E-55 T 28-03-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 CDW54_RS05970 c68fae5ef9202553ad1a8a120568ef2b 122 Pfam PF00238 Ribosomal protein L14p/L23e 2 122 1.9E-51 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CDW54_RS05970 c68fae5ef9202553ad1a8a120568ef2b 122 SUPERFAMILY SSF50193 2 122 3.27E-48 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CDW54_RS06355 42509cdcae9b860dbda0d7559708007a 265 PIRSF PIRSF004789 1 264 2.1E-103 T 28-03-2018 IPR005235 Metallophosphoesterase, YmdB-like CDW54_RS06355 42509cdcae9b860dbda0d7559708007a 265 Gene3D G3DSA:3.60.21.10 1 265 1.2E-49 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CDW54_RS06355 42509cdcae9b860dbda0d7559708007a 265 SUPERFAMILY SSF56300 1 257 2.4E-85 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CDW54_RS06355 42509cdcae9b860dbda0d7559708007a 265 TIGRFAM TIGR00282 TIGR00282: metallophosphoesterase, MG_246/BB_0505 family 1 264 1.8E-108 T 28-03-2018 IPR005235 Metallophosphoesterase, YmdB-like CDW54_RS06355 42509cdcae9b860dbda0d7559708007a 265 Pfam PF13277 YmdB-like protein 4 254 7.0E-109 T 28-03-2018 IPR005235 Metallophosphoesterase, YmdB-like CDW54_RS00845 a78fbe95727ae09fc2d9bc3c5c4ba3f6 175 PRINTS PR00070 Dihydrofolate reductase signature 13 23 1.8E-13 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CDW54_RS00845 a78fbe95727ae09fc2d9bc3c5c4ba3f6 175 PRINTS PR00070 Dihydrofolate reductase signature 93 107 1.8E-13 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CDW54_RS00845 a78fbe95727ae09fc2d9bc3c5c4ba3f6 175 PRINTS PR00070 Dihydrofolate reductase signature 27 35 1.8E-13 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CDW54_RS00845 a78fbe95727ae09fc2d9bc3c5c4ba3f6 175 PRINTS PR00070 Dihydrofolate reductase signature 40 51 1.8E-13 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CDW54_RS00845 a78fbe95727ae09fc2d9bc3c5c4ba3f6 175 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 13 35 - T 28-03-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 CDW54_RS00845 a78fbe95727ae09fc2d9bc3c5c4ba3f6 175 Gene3D G3DSA:3.40.430.10 1 164 4.5E-50 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CDW54_RS00845 a78fbe95727ae09fc2d9bc3c5c4ba3f6 175 PIRSF PIRSF000194 1 164 5.6E-55 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CDW54_RS00845 a78fbe95727ae09fc2d9bc3c5c4ba3f6 175 SUPERFAMILY SSF53597 1 162 5.37E-55 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CDW54_RS00845 a78fbe95727ae09fc2d9bc3c5c4ba3f6 175 Pfam PF00186 Dihydrofolate reductase 1 161 4.4E-61 T 28-03-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CDW54_RS05710 aaca4ead6bea57f15f72631381420203 78 Gene3D G3DSA:4.10.640.10 1 78 1.8E-33 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS05710 aaca4ead6bea57f15f72631381420203 78 PRINTS PR00974 Ribosomal protein S18 family signature 32 42 3.6E-21 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS05710 aaca4ead6bea57f15f72631381420203 78 PRINTS PR00974 Ribosomal protein S18 family signature 50 64 3.6E-21 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS05710 aaca4ead6bea57f15f72631381420203 78 PRINTS PR00974 Ribosomal protein S18 family signature 64 74 3.6E-21 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS05710 aaca4ead6bea57f15f72631381420203 78 PRINTS PR00974 Ribosomal protein S18 family signature 42 49 3.6E-21 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS05710 aaca4ead6bea57f15f72631381420203 78 Pfam PF01084 Ribosomal protein S18 22 72 5.3E-28 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS05710 aaca4ead6bea57f15f72631381420203 78 TIGRFAM TIGR00165 S18: ribosomal protein bS18 10 76 3.6E-31 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS05710 aaca4ead6bea57f15f72631381420203 78 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 6 77 22.432 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS05710 aaca4ead6bea57f15f72631381420203 78 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 24 77 2.0E-24 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS05710 aaca4ead6bea57f15f72631381420203 78 ProSitePatterns PS00057 Ribosomal protein S18 signature. 25 48 - T 28-03-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS05710 aaca4ead6bea57f15f72631381420203 78 SUPERFAMILY SSF46911 4 77 6.67E-30 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS07970 5cf10234b3c35bec911f7584c74ca402 395 TIGRFAM TIGR00131 gal_kin: galactokinase 6 386 3.1E-123 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CDW54_RS07970 5cf10234b3c35bec911f7584c74ca402 395 Gene3D G3DSA:3.30.230.10 2 208 7.2E-54 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CDW54_RS07970 5cf10234b3c35bec911f7584c74ca402 395 Gene3D G3DSA:3.30.70.890 209 378 7.4E-55 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CDW54_RS07970 5cf10234b3c35bec911f7584c74ca402 395 ProSitePatterns PS00106 Galactokinase signature. 27 38 - T 28-03-2018 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CDW54_RS07970 5cf10234b3c35bec911f7584c74ca402 395 Pfam PF10509 Galactokinase galactose-binding signature 10 57 2.0E-18 T 28-03-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CDW54_RS07970 5cf10234b3c35bec911f7584c74ca402 395 Pfam PF00288 GHMP kinases N terminal domain 116 182 4.2E-12 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CDW54_RS07970 5cf10234b3c35bec911f7584c74ca402 395 PRINTS PR00473 Galactokinase signature 27 45 6.5E-28 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CDW54_RS07970 5cf10234b3c35bec911f7584c74ca402 395 PRINTS PR00473 Galactokinase signature 113 131 6.5E-28 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CDW54_RS07970 5cf10234b3c35bec911f7584c74ca402 395 PRINTS PR00473 Galactokinase signature 92 103 6.5E-28 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CDW54_RS07970 5cf10234b3c35bec911f7584c74ca402 395 PRINTS PR00473 Galactokinase signature 270 284 6.5E-28 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CDW54_RS07970 5cf10234b3c35bec911f7584c74ca402 395 PRINTS PR00959 Mevalonate kinase family signature 25 49 4.6E-43 T 28-03-2018 CDW54_RS07970 5cf10234b3c35bec911f7584c74ca402 395 PRINTS PR00959 Mevalonate kinase family signature 120 142 4.6E-43 T 28-03-2018 CDW54_RS07970 5cf10234b3c35bec911f7584c74ca402 395 PRINTS PR00959 Mevalonate kinase family signature 334 351 4.6E-43 T 28-03-2018 CDW54_RS07970 5cf10234b3c35bec911f7584c74ca402 395 PRINTS PR00959 Mevalonate kinase family signature 163 182 4.6E-43 T 28-03-2018 CDW54_RS07970 5cf10234b3c35bec911f7584c74ca402 395 Hamap MF_00246 Galactokinase [galK]. 25 387 49.359 T 28-03-2018 IPR022963 Galactokinase, bacterial GO:0004335|GO:0006012 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CDW54_RS07970 5cf10234b3c35bec911f7584c74ca402 395 Pfam PF08544 GHMP kinases C terminal 286 355 1.6E-13 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CDW54_RS07970 5cf10234b3c35bec911f7584c74ca402 395 PIRSF PIRSF000530 1 389 3.8E-125 T 28-03-2018 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CDW54_RS07970 5cf10234b3c35bec911f7584c74ca402 395 SUPERFAMILY SSF54211 3 204 2.66E-62 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CDW54_RS07970 5cf10234b3c35bec911f7584c74ca402 395 SUPERFAMILY SSF55060 206 386 8.02E-59 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CDW54_RS07970 5cf10234b3c35bec911f7584c74ca402 395 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 122 133 - T 28-03-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 CDW54_RS00305 4798e5dc632042f1327ae47d7c3e749c 468 SUPERFAMILY SSF55424 346 467 9.97E-36 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CDW54_RS00305 4798e5dc632042f1327ae47d7c3e749c 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 282 6.4E-41 T 28-03-2018 CDW54_RS00305 4798e5dc632042f1327ae47d7c3e749c 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 6.4E-41 T 28-03-2018 CDW54_RS00305 4798e5dc632042f1327ae47d7c3e749c 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 141 159 6.4E-41 T 28-03-2018 CDW54_RS00305 4798e5dc632042f1327ae47d7c3e749c 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 179 197 6.4E-41 T 28-03-2018 CDW54_RS00305 4798e5dc632042f1327ae47d7c3e749c 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 295 317 6.4E-41 T 28-03-2018 CDW54_RS00305 4798e5dc632042f1327ae47d7c3e749c 468 Gene3D G3DSA:3.30.390.30 348 462 1.8E-35 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CDW54_RS00305 4798e5dc632042f1327ae47d7c3e749c 468 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 11 330 9.4E-73 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS00305 4798e5dc632042f1327ae47d7c3e749c 468 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 349 456 6.3E-31 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CDW54_RS00305 4798e5dc632042f1327ae47d7c3e749c 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 179 204 6.2E-73 T 28-03-2018 CDW54_RS00305 4798e5dc632042f1327ae47d7c3e749c 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 432 452 6.2E-73 T 28-03-2018 CDW54_RS00305 4798e5dc632042f1327ae47d7c3e749c 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 345 366 6.2E-73 T 28-03-2018 CDW54_RS00305 4798e5dc632042f1327ae47d7c3e749c 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 267 281 6.2E-73 T 28-03-2018 CDW54_RS00305 4798e5dc632042f1327ae47d7c3e749c 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 310 317 6.2E-73 T 28-03-2018 CDW54_RS00305 4798e5dc632042f1327ae47d7c3e749c 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 410 425 6.2E-73 T 28-03-2018 CDW54_RS00305 4798e5dc632042f1327ae47d7c3e749c 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 43 58 6.2E-73 T 28-03-2018 CDW54_RS00305 4798e5dc632042f1327ae47d7c3e749c 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 6.2E-73 T 28-03-2018 CDW54_RS00305 4798e5dc632042f1327ae47d7c3e749c 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 144 153 6.2E-73 T 28-03-2018 CDW54_RS00305 4798e5dc632042f1327ae47d7c3e749c 468 Gene3D G3DSA:3.50.50.60 122 254 2.2E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS00305 4798e5dc632042f1327ae47d7c3e749c 468 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 10 468 1.1E-160 T 28-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CDW54_RS00305 4798e5dc632042f1327ae47d7c3e749c 468 Gene3D G3DSA:1.10.287.990 43 110 2.7E-19 T 28-03-2018 CDW54_RS00305 4798e5dc632042f1327ae47d7c3e749c 468 Gene3D G3DSA:3.40.50.720 11 42 0.0074 T 28-03-2018 CDW54_RS00305 4798e5dc632042f1327ae47d7c3e749c 468 Gene3D G3DSA:3.50.50.60 271 347 2.6E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS00305 4798e5dc632042f1327ae47d7c3e749c 468 SUPERFAMILY SSF51905 9 339 2.09E-66 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS00305 4798e5dc632042f1327ae47d7c3e749c 468 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 44 54 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CDW54_RS00305 4798e5dc632042f1327ae47d7c3e749c 468 PIRSF PIRSF000350 3 456 1.3E-94 T 28-03-2018 CDW54_RS04775 20373374f474281787492af452ef7973 334 PIRSF PIRSF006621 4 332 2.2E-108 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CDW54_RS04775 20373374f474281787492af452ef7973 334 SUPERFAMILY SSF51395 14 324 3.85E-91 T 28-03-2018 CDW54_RS04775 20373374f474281787492af452ef7973 334 Gene3D G3DSA:1.10.1200.80 256 332 8.2E-17 T 28-03-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 CDW54_RS04775 20373374f474281787492af452ef7973 334 Gene3D G3DSA:3.20.20.70 23 252 1.2E-61 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDW54_RS04775 20373374f474281787492af452ef7973 334 Pfam PF01207 Dihydrouridine synthase (Dus) 18 323 1.2E-103 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CDW54_RS04775 20373374f474281787492af452ef7973 334 Gene3D G3DSA:3.20.20.70 2 22 0.077 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDW54_RS04775 20373374f474281787492af452ef7973 334 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 7 325 1.8E-125 T 28-03-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 CDW54_RS04775 20373374f474281787492af452ef7973 334 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 99 117 - T 28-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 CDW54_RS06480 ac709ec8a34dd23b32e9c638bf14293a 89 SUPERFAMILY SSF47060 3 89 8.24E-36 T 28-03-2018 IPR009068 S15/NS1, RNA-binding CDW54_RS06480 ac709ec8a34dd23b32e9c638bf14293a 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 5 89 3.5E-39 T 28-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS06480 ac709ec8a34dd23b32e9c638bf14293a 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 22.226 T 28-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS06480 ac709ec8a34dd23b32e9c638bf14293a 89 Pfam PF00312 Ribosomal protein S15 8 88 1.7E-36 T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS06480 ac709ec8a34dd23b32e9c638bf14293a 89 SMART SM01387 8 88 1.4E-50 T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS06480 ac709ec8a34dd23b32e9c638bf14293a 89 Gene3D G3DSA:1.10.287.10 2 89 3.3E-34 T 28-03-2018 CDW54_RS06480 ac709ec8a34dd23b32e9c638bf14293a 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 88 1.0E-39 T 28-03-2018 CDW54_RS05045 8454d33bd2cebfda31aae304e9db503e 422 SUPERFAMILY SSF63411 5 212 8.98E-20 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CDW54_RS05045 8454d33bd2cebfda31aae304e9db503e 422 Pfam PF05193 Peptidase M16 inactive domain 179 354 1.8E-26 T 28-03-2018 IPR007863 Peptidase M16, C-terminal CDW54_RS05045 8454d33bd2cebfda31aae304e9db503e 422 Gene3D G3DSA:3.30.830.10 233 408 2.0E-30 T 28-03-2018 CDW54_RS05045 8454d33bd2cebfda31aae304e9db503e 422 Gene3D G3DSA:3.30.830.10 2 222 5.1E-21 T 28-03-2018 CDW54_RS05045 8454d33bd2cebfda31aae304e9db503e 422 SUPERFAMILY SSF63411 244 409 1.75E-31 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CDW54_RS04060 a9ac858df139a0ff607cad1ca08ac11e 315 PRINTS PR00069 Aldo-keto reductase signature 141 158 1.1E-13 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CDW54_RS04060 a9ac858df139a0ff607cad1ca08ac11e 315 PRINTS PR00069 Aldo-keto reductase signature 110 128 1.1E-13 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CDW54_RS04060 a9ac858df139a0ff607cad1ca08ac11e 315 PRINTS PR00069 Aldo-keto reductase signature 44 68 1.1E-13 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CDW54_RS04060 a9ac858df139a0ff607cad1ca08ac11e 315 SUPERFAMILY SSF51430 1 313 4.85E-92 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CDW54_RS04060 a9ac858df139a0ff607cad1ca08ac11e 315 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 141 158 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CDW54_RS04060 a9ac858df139a0ff607cad1ca08ac11e 315 Pfam PF00248 Aldo/keto reductase family 16 311 5.4E-78 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CDW54_RS04060 a9ac858df139a0ff607cad1ca08ac11e 315 Gene3D G3DSA:3.20.20.100 1 315 2.4E-96 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CDW54_RS06280 abd172535ed4376c4042daf9d10bd9f5 392 Pfam PF00872 Transposase, Mutator family 7 371 1.7E-110 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CDW54_RS06280 abd172535ed4376c4042daf9d10bd9f5 392 Gene3D G3DSA:3.30.420.10 146 385 3.4E-5 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS10325 abd172535ed4376c4042daf9d10bd9f5 392 Pfam PF00872 Transposase, Mutator family 7 371 1.7E-110 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CDW54_RS10325 abd172535ed4376c4042daf9d10bd9f5 392 Gene3D G3DSA:3.30.420.10 146 385 3.4E-5 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS07445 abd172535ed4376c4042daf9d10bd9f5 392 Pfam PF00872 Transposase, Mutator family 7 371 1.7E-110 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CDW54_RS07445 abd172535ed4376c4042daf9d10bd9f5 392 Gene3D G3DSA:3.30.420.10 146 385 3.4E-5 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS08975 abd172535ed4376c4042daf9d10bd9f5 392 Pfam PF00872 Transposase, Mutator family 7 371 1.7E-110 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CDW54_RS08975 abd172535ed4376c4042daf9d10bd9f5 392 Gene3D G3DSA:3.30.420.10 146 385 3.4E-5 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS01695 abd172535ed4376c4042daf9d10bd9f5 392 Pfam PF00872 Transposase, Mutator family 7 371 1.7E-110 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CDW54_RS01695 abd172535ed4376c4042daf9d10bd9f5 392 Gene3D G3DSA:3.30.420.10 146 385 3.4E-5 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS06095 abd172535ed4376c4042daf9d10bd9f5 392 Pfam PF00872 Transposase, Mutator family 7 371 1.7E-110 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CDW54_RS06095 abd172535ed4376c4042daf9d10bd9f5 392 Gene3D G3DSA:3.30.420.10 146 385 3.4E-5 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS03300 abd172535ed4376c4042daf9d10bd9f5 392 Pfam PF00872 Transposase, Mutator family 7 371 1.7E-110 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CDW54_RS03300 abd172535ed4376c4042daf9d10bd9f5 392 Gene3D G3DSA:3.30.420.10 146 385 3.4E-5 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS02650 abd172535ed4376c4042daf9d10bd9f5 392 Pfam PF00872 Transposase, Mutator family 7 371 1.7E-110 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CDW54_RS02650 abd172535ed4376c4042daf9d10bd9f5 392 Gene3D G3DSA:3.30.420.10 146 385 3.4E-5 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS03740 abd172535ed4376c4042daf9d10bd9f5 392 Pfam PF00872 Transposase, Mutator family 7 371 1.7E-110 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CDW54_RS03740 abd172535ed4376c4042daf9d10bd9f5 392 Gene3D G3DSA:3.30.420.10 146 385 3.4E-5 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS07805 abd172535ed4376c4042daf9d10bd9f5 392 Pfam PF00872 Transposase, Mutator family 7 371 1.7E-110 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CDW54_RS07805 abd172535ed4376c4042daf9d10bd9f5 392 Gene3D G3DSA:3.30.420.10 146 385 3.4E-5 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS04275 7f213928ea0affd90145f27e5dc9ffae 472 Pfam PF13347 MFS/sugar transport protein 26 456 9.3E-75 T 28-03-2018 CDW54_RS04275 7f213928ea0affd90145f27e5dc9ffae 472 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 24 467 4.0E-89 T 28-03-2018 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 CDW54_RS04275 7f213928ea0affd90145f27e5dc9ffae 472 SUPERFAMILY SSF103473 26 459 9.02E-36 T 28-03-2018 IPR020846 Major facilitator superfamily domain CDW54_RS04275 7f213928ea0affd90145f27e5dc9ffae 472 Gene3D G3DSA:1.20.1250.20 240 460 1.6E-21 T 28-03-2018 CDW54_RS04275 7f213928ea0affd90145f27e5dc9ffae 472 Gene3D G3DSA:1.20.1250.20 25 238 2.0E-12 T 28-03-2018 CDW54_RS06765 2c25ab1d139f4bcdbfb3358ce16b9f24 66 SUPERFAMILY SSF143034 2 62 2.62E-18 T 28-03-2018 CDW54_RS06765 2c25ab1d139f4bcdbfb3358ce16b9f24 66 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 28-03-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS06765 2c25ab1d139f4bcdbfb3358ce16b9f24 66 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 62 8.5E-20 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CDW54_RS06765 2c25ab1d139f4bcdbfb3358ce16b9f24 66 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 17.282 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CDW54_RS06765 2c25ab1d139f4bcdbfb3358ce16b9f24 66 PRINTS PR00064 Ribosomal protein L35 signature 36 54 1.1E-16 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CDW54_RS06765 2c25ab1d139f4bcdbfb3358ce16b9f24 66 PRINTS PR00064 Ribosomal protein L35 signature 3 20 1.1E-16 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CDW54_RS06765 2c25ab1d139f4bcdbfb3358ce16b9f24 66 PRINTS PR00064 Ribosomal protein L35 signature 21 35 1.1E-16 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CDW54_RS06765 2c25ab1d139f4bcdbfb3358ce16b9f24 66 Pfam PF01632 Ribosomal protein L35 2 61 2.2E-19 T 28-03-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS10050 2e7a438f577cbad631eb5b50ab40950a 254 Gene3D G3DSA:3.20.20.140 1 235 4.7E-23 T 28-03-2018 CDW54_RS10050 2e7a438f577cbad631eb5b50ab40950a 254 SUPERFAMILY SSF89550 1 204 4.32E-16 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CDW54_RS10050 2e7a438f577cbad631eb5b50ab40950a 254 PIRSF PIRSF016557 1 254 1.7E-91 T 28-03-2018 IPR016667 Capsular polysaccharide synthesis, CpsB/CapC GO:0004725|GO:0030145 CDW54_RS07340 495230e0ed34675f529287b4b4882d7f 631 Gene3D G3DSA:2.70.70.10 471 628 1.2E-57 T 28-03-2018 CDW54_RS07340 495230e0ed34675f529287b4b4882d7f 631 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 485 604 3.2E-44 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CDW54_RS07340 495230e0ed34675f529287b4b4882d7f 631 Gene3D G3DSA:3.30.1360.60 31 107 2.0E-27 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CDW54_RS07340 495230e0ed34675f529287b4b4882d7f 631 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 46 63 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CDW54_RS07340 495230e0ed34675f529287b4b4882d7f 631 Pfam PF02378 Phosphotransferase system, EIIC 136 413 2.0E-33 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CDW54_RS07340 495230e0ed34675f529287b4b4882d7f 631 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 546 558 - T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CDW54_RS07340 495230e0ed34675f529287b4b4882d7f 631 Pfam PF00367 phosphotransferase system, EIIB 35 68 1.6E-13 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CDW54_RS07340 495230e0ed34675f529287b4b4882d7f 631 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 484 607 9.6E-51 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CDW54_RS07340 495230e0ed34675f529287b4b4882d7f 631 SUPERFAMILY SSF51261 478 618 5.93E-53 T 28-03-2018 IPR011055 Duplicated hybrid motif CDW54_RS07340 495230e0ed34675f529287b4b4882d7f 631 SUPERFAMILY SSF55604 33 108 5.23E-21 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CDW54_RS07340 495230e0ed34675f529287b4b4882d7f 631 TIGRFAM TIGR01995 PTS-II-ABC-beta: PTS system, beta-glucoside-specific IIABC component 30 618 1.5E-220 T 28-03-2018 IPR011297 Phosphotransferase system, beta-glucoside-specific IIABC component GO:0005886|GO:0008982|GO:0009401 CDW54_RS12380 cbd2f1d8a2b4b821a5babb3c3a4c7550 426 Pfam PF01979 Amidohydrolase family 52 421 5.5E-49 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CDW54_RS12380 cbd2f1d8a2b4b821a5babb3c3a4c7550 426 Gene3D G3DSA:3.20.20.140 69 407 9.5E-103 T 28-03-2018 CDW54_RS12380 cbd2f1d8a2b4b821a5babb3c3a4c7550 426 SUPERFAMILY SSF51556 55 369 1.54E-104 T 28-03-2018 IPR032466 Metal-dependent hydrolase CDW54_RS12380 cbd2f1d8a2b4b821a5babb3c3a4c7550 426 Hamap MF_00220_B Dihydroorotase [pyrC]. 2 425 44.567 T 28-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDW54_RS12380 cbd2f1d8a2b4b821a5babb3c3a4c7550 426 ProSitePatterns PS00483 Dihydroorotase signature 2. 303 314 - T 28-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDW54_RS12380 cbd2f1d8a2b4b821a5babb3c3a4c7550 426 ProSitePatterns PS00482 Dihydroorotase signature 1. 58 66 - T 28-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDW54_RS12380 cbd2f1d8a2b4b821a5babb3c3a4c7550 426 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 18 424 1.0E-131 T 28-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDW54_RS12380 cbd2f1d8a2b4b821a5babb3c3a4c7550 426 SUPERFAMILY SSF51338 1 54 7.73E-30 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CDW54_RS12380 cbd2f1d8a2b4b821a5babb3c3a4c7550 426 SUPERFAMILY SSF51338 367 426 7.73E-30 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CDW54_RS12380 cbd2f1d8a2b4b821a5babb3c3a4c7550 426 Gene3D G3DSA:2.30.40.10 1 68 1.1E-22 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CDW54_RS08740 8e293f804c9fea89ebca4ffaf9150f71 246 Gene3D G3DSA:3.40.50.2300 1 131 1.9E-10 T 28-03-2018 CDW54_RS08740 8e293f804c9fea89ebca4ffaf9150f71 246 SUPERFAMILY SSF52172 5 127 2.11E-9 T 28-03-2018 IPR011006 CheY-like superfamily CDW54_RS08740 8e293f804c9fea89ebca4ffaf9150f71 246 Pfam PF04397 LytTr DNA-binding domain 145 236 5.8E-10 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CDW54_RS08740 8e293f804c9fea89ebca4ffaf9150f71 246 SMART SM00448 2 119 0.0034 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDW54_RS08740 8e293f804c9fea89ebca4ffaf9150f71 246 Pfam PF00072 Response regulator receiver domain 5 110 2.0E-9 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDW54_RS08740 8e293f804c9fea89ebca4ffaf9150f71 246 Gene3D G3DSA:2.40.50.40 132 203 1.1E-9 T 28-03-2018 CDW54_RS08740 8e293f804c9fea89ebca4ffaf9150f71 246 SMART SM00850 141 238 2.1E-7 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CDW54_RS01890 27d8d5688181a841a8d4d0d78644c237 275 Gene3D G3DSA:3.90.550.10 13 264 1.6E-12 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDW54_RS01890 27d8d5688181a841a8d4d0d78644c237 275 Pfam PF00535 Glycosyl transferase family 2 36 110 4.7E-6 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CDW54_RS01890 27d8d5688181a841a8d4d0d78644c237 275 SUPERFAMILY SSF53448 32 235 1.88E-17 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDW54_RS09270 a731ee0d67fc718b7c1d002b88600a30 100 Pfam PF06949 Protein of unknown function (DUF1292) 21 97 1.3E-15 T 28-03-2018 IPR009711 Uncharacterised protein family UPF0473 CDW54_RS09270 a731ee0d67fc718b7c1d002b88600a30 100 Hamap MF_01448 UPF0473 protein . 12 98 21.073 T 28-03-2018 IPR009711 Uncharacterised protein family UPF0473 CDW54_RS03180 e1db07f465eee4bc23bbb495f55c01d1 669 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 16 25 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDW54_RS03180 e1db07f465eee4bc23bbb495f55c01d1 669 Pfam PF01588 Putative tRNA binding domain 572 666 1.9E-27 T 28-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CDW54_RS03180 e1db07f465eee4bc23bbb495f55c01d1 669 Gene3D G3DSA:1.10.730.10 357 523 2.2E-41 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDW54_RS03180 e1db07f465eee4bc23bbb495f55c01d1 669 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 7 496 6.1E-177 T 28-03-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CDW54_RS03180 e1db07f465eee4bc23bbb495f55c01d1 669 Pfam PF09334 tRNA synthetases class I (M) 7 372 9.5E-117 T 28-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDW54_RS03180 e1db07f465eee4bc23bbb495f55c01d1 669 Gene3D G3DSA:2.40.50.140 558 669 2.3E-29 T 28-03-2018 CDW54_RS03180 e1db07f465eee4bc23bbb495f55c01d1 669 SUPERFAMILY SSF50249 562 668 5.39E-30 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDW54_RS03180 e1db07f465eee4bc23bbb495f55c01d1 669 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 540 668 1.5E-39 T 28-03-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CDW54_RS03180 e1db07f465eee4bc23bbb495f55c01d1 669 Hamap MF_01228 Methionine--tRNA ligase [metG]. 2 520 51.551 T 28-03-2018 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CDW54_RS03180 e1db07f465eee4bc23bbb495f55c01d1 669 Pfam PF08264 Anticodon-binding domain of tRNA 397 506 2.8E-8 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CDW54_RS03180 e1db07f465eee4bc23bbb495f55c01d1 669 SUPERFAMILY SSF52374 4 363 2.39E-114 T 28-03-2018 CDW54_RS03180 e1db07f465eee4bc23bbb495f55c01d1 669 Gene3D G3DSA:3.40.50.620 4 356 1.8E-102 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDW54_RS03180 e1db07f465eee4bc23bbb495f55c01d1 669 PRINTS PR01041 Methionyl-tRNA synthetase signature 9 22 1.9E-32 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CDW54_RS03180 e1db07f465eee4bc23bbb495f55c01d1 669 PRINTS PR01041 Methionyl-tRNA synthetase signature 360 371 1.9E-32 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CDW54_RS03180 e1db07f465eee4bc23bbb495f55c01d1 669 PRINTS PR01041 Methionyl-tRNA synthetase signature 235 246 1.9E-32 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CDW54_RS03180 e1db07f465eee4bc23bbb495f55c01d1 669 PRINTS PR01041 Methionyl-tRNA synthetase signature 41 55 1.9E-32 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CDW54_RS03180 e1db07f465eee4bc23bbb495f55c01d1 669 PRINTS PR01041 Methionyl-tRNA synthetase signature 89 100 1.9E-32 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CDW54_RS03180 e1db07f465eee4bc23bbb495f55c01d1 669 PRINTS PR01041 Methionyl-tRNA synthetase signature 268 283 1.9E-32 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CDW54_RS03180 e1db07f465eee4bc23bbb495f55c01d1 669 SUPERFAMILY SSF47323 362 580 3.36E-47 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDW54_RS01955 42923a18b742c7e3f8c7d3a8eac76011 60 Pfam PF11384 Protein of unknown function (DUF3188) 4 52 2.3E-17 T 28-03-2018 IPR021524 Protein of unknown function DUF3188 CDW54_RS11005 579c5bf8312e418d3b7c04fcb83b446e 500 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 318 500 1.1E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS11005 579c5bf8312e418d3b7c04fcb83b446e 500 Gene3D G3DSA:3.40.190.10 40 151 6.3E-29 T 28-03-2018 CDW54_RS11005 579c5bf8312e418d3b7c04fcb83b446e 500 SMART SM00062 51 273 1.1E-54 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CDW54_RS11005 579c5bf8312e418d3b7c04fcb83b446e 500 Gene3D G3DSA:3.40.190.10 152 220 5.2E-20 T 28-03-2018 CDW54_RS11005 579c5bf8312e418d3b7c04fcb83b446e 500 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 53 270 1.7E-55 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CDW54_RS11005 579c5bf8312e418d3b7c04fcb83b446e 500 Gene3D G3DSA:1.10.3720.10 221 500 3.2E-49 T 28-03-2018 CDW54_RS11005 579c5bf8312e418d3b7c04fcb83b446e 500 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 296 394 2.9E-28 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CDW54_RS11005 579c5bf8312e418d3b7c04fcb83b446e 500 SUPERFAMILY SSF161098 298 491 7.59E-47 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS11005 579c5bf8312e418d3b7c04fcb83b446e 500 SUPERFAMILY SSF53850 49 270 1.01E-58 T 28-03-2018 CDW54_RS04825 d6ca898dc1f7088e2a511c73276a5bf7 186 SUPERFAMILY SSF53178 1 186 9.16E-68 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CDW54_RS04825 d6ca898dc1f7088e2a511c73276a5bf7 186 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 107 117 - T 28-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 CDW54_RS04825 d6ca898dc1f7088e2a511c73276a5bf7 186 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 1 186 6.4E-68 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CDW54_RS04825 d6ca898dc1f7088e2a511c73276a5bf7 186 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 14 27 - T 28-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 CDW54_RS04825 d6ca898dc1f7088e2a511c73276a5bf7 186 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 1 178 37.417 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CDW54_RS04825 d6ca898dc1f7088e2a511c73276a5bf7 186 Pfam PF01195 Peptidyl-tRNA hydrolase 3 186 1.2E-59 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CDW54_RS04825 d6ca898dc1f7088e2a511c73276a5bf7 186 Gene3D G3DSA:3.40.50.1470 1 186 4.2E-72 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CDW54_RS06500 3ac81116c715541c9ea90dcbb804296e 433 SUPERFAMILY SSF54631 204 343 5.94E-27 T 28-03-2018 CDW54_RS06500 3ac81116c715541c9ea90dcbb804296e 433 SMART SM00116 224 273 0.47 T 28-03-2018 IPR000644 CBS domain CDW54_RS06500 3ac81116c715541c9ea90dcbb804296e 433 SMART SM00116 286 334 7.6 T 28-03-2018 IPR000644 CBS domain CDW54_RS06500 3ac81116c715541c9ea90dcbb804296e 433 Pfam PF03471 Transporter associated domain 350 427 1.1E-14 T 28-03-2018 IPR005170 Transporter-associated domain CDW54_RS06500 3ac81116c715541c9ea90dcbb804296e 433 Pfam PF01595 Domain of unknown function DUF21 6 200 1.8E-42 T 28-03-2018 IPR002550 Domain of unknown function DUF21 CDW54_RS06500 3ac81116c715541c9ea90dcbb804296e 433 SMART SM01091 349 429 6.7E-16 T 28-03-2018 IPR005170 Transporter-associated domain CDW54_RS06500 3ac81116c715541c9ea90dcbb804296e 433 Gene3D G3DSA:3.30.465.10 341 429 1.5E-17 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CDW54_RS06500 3ac81116c715541c9ea90dcbb804296e 433 SUPERFAMILY SSF56176 344 426 4.36E-15 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CDW54_RS06500 3ac81116c715541c9ea90dcbb804296e 433 Pfam PF00571 CBS domain 285 334 1.6E-5 T 28-03-2018 IPR000644 CBS domain CDW54_RS06500 3ac81116c715541c9ea90dcbb804296e 433 Pfam PF00571 CBS domain 221 270 1.7E-5 T 28-03-2018 IPR000644 CBS domain CDW54_RS06500 3ac81116c715541c9ea90dcbb804296e 433 Gene3D G3DSA:3.10.580.10 194 340 8.9E-27 T 28-03-2018 CDW54_RS11195 b3da73823d3ae6e2c06519abe0311ed5 490 ProSitePatterns PS00571 Amidases signature. 151 182 - T 28-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CDW54_RS11195 b3da73823d3ae6e2c06519abe0311ed5 490 Gene3D G3DSA:3.90.1300.10 2 484 1.7E-163 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CDW54_RS11195 b3da73823d3ae6e2c06519abe0311ed5 490 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 12 476 92.678 T 28-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CDW54_RS11195 b3da73823d3ae6e2c06519abe0311ed5 490 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 13 476 5.3E-195 T 28-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CDW54_RS11195 b3da73823d3ae6e2c06519abe0311ed5 490 SUPERFAMILY SSF75304 4 482 6.02E-158 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CDW54_RS11195 b3da73823d3ae6e2c06519abe0311ed5 490 Pfam PF01425 Amidase 25 463 8.3E-154 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CDW54_RS11080 4849bd11778ee86ed4d250c50c96e7ae 451 Gene3D G3DSA:3.40.120.10 165 265 9.4E-21 T 28-03-2018 CDW54_RS11080 4849bd11778ee86ed4d250c50c96e7ae 451 ProSitePatterns PS00018 EF-hand calcium-binding domain. 243 255 - T 28-03-2018 IPR018247 EF-Hand 1, calcium-binding site CDW54_RS11080 4849bd11778ee86ed4d250c50c96e7ae 451 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 447 44.032 T 28-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDW54_RS11080 4849bd11778ee86ed4d250c50c96e7ae 451 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 162 256 6.7E-14 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDW54_RS11080 4849bd11778ee86ed4d250c50c96e7ae 451 SUPERFAMILY SSF55957 360 449 1.57E-26 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDW54_RS11080 4849bd11778ee86ed4d250c50c96e7ae 451 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 260 369 4.0E-36 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDW54_RS11080 4849bd11778ee86ed4d250c50c96e7ae 451 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 96 110 3.3E-13 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDW54_RS11080 4849bd11778ee86ed4d250c50c96e7ae 451 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 236 251 3.3E-13 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDW54_RS11080 4849bd11778ee86ed4d250c50c96e7ae 451 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 176 195 3.3E-13 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDW54_RS11080 4849bd11778ee86ed4d250c50c96e7ae 451 SUPERFAMILY SSF53738 3 183 2.43E-45 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDW54_RS11080 4849bd11778ee86ed4d250c50c96e7ae 451 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 376 444 7.1E-18 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDW54_RS11080 4849bd11778ee86ed4d250c50c96e7ae 451 Gene3D G3DSA:3.30.310.50 377 449 2.2E-21 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDW54_RS11080 4849bd11778ee86ed4d250c50c96e7ae 451 SUPERFAMILY SSF53738 162 259 8.24E-24 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDW54_RS11080 4849bd11778ee86ed4d250c50c96e7ae 451 Gene3D G3DSA:3.40.120.10 266 376 2.1E-35 T 28-03-2018 CDW54_RS11080 4849bd11778ee86ed4d250c50c96e7ae 451 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 97 106 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDW54_RS11080 4849bd11778ee86ed4d250c50c96e7ae 451 Gene3D G3DSA:3.40.120.10 2 164 3.6E-45 T 28-03-2018 CDW54_RS11080 4849bd11778ee86ed4d250c50c96e7ae 451 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 446 6.2E-185 T 28-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDW54_RS11080 4849bd11778ee86ed4d250c50c96e7ae 451 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 137 8.8E-43 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDW54_RS11080 4849bd11778ee86ed4d250c50c96e7ae 451 SUPERFAMILY SSF53738 260 368 2.71E-35 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDW54_RS12355 5a51de5d22868be38a909a42c4480ac3 238 SUPERFAMILY SSF51366 7 237 1.56E-68 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CDW54_RS12355 5a51de5d22868be38a909a42c4480ac3 238 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 5 238 39.5 T 28-03-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CDW54_RS12355 5a51de5d22868be38a909a42c4480ac3 238 Gene3D G3DSA:3.20.20.70 4 238 1.4E-55 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDW54_RS12355 5a51de5d22868be38a909a42c4480ac3 238 SMART SM00934 7 233 4.2E-87 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CDW54_RS12355 5a51de5d22868be38a909a42c4480ac3 238 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 9 232 4.2E-42 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CDW54_RS12355 5a51de5d22868be38a909a42c4480ac3 238 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 60 73 - T 28-03-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CDW54_RS12355 5a51de5d22868be38a909a42c4480ac3 238 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 8 234 7.1E-61 T 28-03-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CDW54_RS00290 dc3ef6483cbe005c7bab95264ff32254 609 Gene3D G3DSA:3.40.50.300 2 69 4.2E-9 T 28-03-2018 CDW54_RS00290 dc3ef6483cbe005c7bab95264ff32254 609 Gene3D G3DSA:2.40.30.10 198 306 1.6E-20 T 28-03-2018 CDW54_RS00290 dc3ef6483cbe005c7bab95264ff32254 609 SUPERFAMILY SSF52540 3 211 3.32E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS00290 dc3ef6483cbe005c7bab95264ff32254 609 Gene3D G3DSA:3.30.70.240 406 484 8.4E-20 T 28-03-2018 CDW54_RS00290 dc3ef6483cbe005c7bab95264ff32254 609 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 7 603 1.2E-290 T 28-03-2018 IPR006298 GTP-binding protein TypA GO:0005525 CDW54_RS00290 dc3ef6483cbe005c7bab95264ff32254 609 Pfam PF00009 Elongation factor Tu GTP binding domain 6 199 8.2E-54 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDW54_RS00290 dc3ef6483cbe005c7bab95264ff32254 609 PRINTS PR00315 GTP-binding elongation factor signature 53 61 1.8E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDW54_RS00290 dc3ef6483cbe005c7bab95264ff32254 609 PRINTS PR00315 GTP-binding elongation factor signature 9 22 1.8E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDW54_RS00290 dc3ef6483cbe005c7bab95264ff32254 609 PRINTS PR00315 GTP-binding elongation factor signature 73 83 1.8E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDW54_RS00290 dc3ef6483cbe005c7bab95264ff32254 609 PRINTS PR00315 GTP-binding elongation factor signature 125 134 1.8E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDW54_RS00290 dc3ef6483cbe005c7bab95264ff32254 609 PRINTS PR00315 GTP-binding elongation factor signature 89 100 1.8E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDW54_RS00290 dc3ef6483cbe005c7bab95264ff32254 609 SUPERFAMILY SSF54980 402 517 1.77E-29 T 28-03-2018 IPR035647 EF-G domain III/V-like CDW54_RS00290 dc3ef6483cbe005c7bab95264ff32254 609 Pfam PF00679 Elongation factor G C-terminus 400 479 2.3E-24 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CDW54_RS00290 dc3ef6483cbe005c7bab95264ff32254 609 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 46 61 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CDW54_RS00290 dc3ef6483cbe005c7bab95264ff32254 609 Gene3D G3DSA:3.40.50.300 70 197 9.6E-32 T 28-03-2018 CDW54_RS00290 dc3ef6483cbe005c7bab95264ff32254 609 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 7 148 2.0E-23 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CDW54_RS00290 dc3ef6483cbe005c7bab95264ff32254 609 SUPERFAMILY SSF50447 154 303 7.49E-33 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CDW54_RS00290 dc3ef6483cbe005c7bab95264ff32254 609 SMART SM00838 399 484 4.0E-5 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CDW54_RS00290 dc3ef6483cbe005c7bab95264ff32254 609 SUPERFAMILY SSF54980 306 391 1.83E-15 T 28-03-2018 IPR035647 EF-G domain III/V-like CDW54_RS00290 dc3ef6483cbe005c7bab95264ff32254 609 Gene3D G3DSA:3.30.70.870 307 405 1.3E-33 T 28-03-2018 CDW54_RS00290 dc3ef6483cbe005c7bab95264ff32254 609 Pfam PF03144 Elongation factor Tu domain 2 223 293 2.1E-12 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CDW54_RS00290 dc3ef6483cbe005c7bab95264ff32254 609 Gene3D G3DSA:2.40.50.250 487 577 8.6E-38 T 28-03-2018 CDW54_RS07865 cf580b4fc53f67d51ee13ae28f958ce0 156 ProSitePatterns PS00460 Glutathione peroxidases active site. 23 38 - T 28-03-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 CDW54_RS07865 cf580b4fc53f67d51ee13ae28f958ce0 156 PIRSF PIRSF000303 1 156 3.6E-63 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CDW54_RS07865 cf580b4fc53f67d51ee13ae28f958ce0 156 PRINTS PR01011 Glutathione peroxidase family signature 56 72 2.9E-13 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CDW54_RS07865 cf580b4fc53f67d51ee13ae28f958ce0 156 PRINTS PR01011 Glutathione peroxidase family signature 21 38 2.9E-13 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CDW54_RS07865 cf580b4fc53f67d51ee13ae28f958ce0 156 PRINTS PR01011 Glutathione peroxidase family signature 120 129 2.9E-13 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CDW54_RS07865 cf580b4fc53f67d51ee13ae28f958ce0 156 Gene3D G3DSA:3.40.30.10 1 156 1.4E-43 T 28-03-2018 CDW54_RS07865 cf580b4fc53f67d51ee13ae28f958ce0 156 SUPERFAMILY SSF52833 1 156 2.82E-52 T 28-03-2018 IPR012336 Thioredoxin-like fold CDW54_RS07865 cf580b4fc53f67d51ee13ae28f958ce0 156 Pfam PF00255 Glutathione peroxidase 3 109 1.2E-33 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CDW54_RS07865 cf580b4fc53f67d51ee13ae28f958ce0 156 ProSitePatterns PS00763 Glutathione peroxidases signature 2. 59 66 - T 28-03-2018 IPR029760 Glutathione peroxidase conserved site Reactome: R-HSA-3299685 CDW54_RS01215 4346449eba94e21984b12846ed0076e0 256 ProSitePatterns PS00894 DeoR-type HTH domain signature. 11 45 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CDW54_RS01215 4346449eba94e21984b12846ed0076e0 256 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 43 61 4.1E-7 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CDW54_RS01215 4346449eba94e21984b12846ed0076e0 256 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 29 43 4.1E-7 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CDW54_RS01215 4346449eba94e21984b12846ed0076e0 256 Pfam PF00455 DeoR C terminal sensor domain 80 233 1.5E-37 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain CDW54_RS01215 4346449eba94e21984b12846ed0076e0 256 Gene3D G3DSA:1.10.10.10 1 75 1.2E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS01215 4346449eba94e21984b12846ed0076e0 256 SUPERFAMILY SSF46785 8 65 5.09E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS01215 4346449eba94e21984b12846ed0076e0 256 SMART SM01134 74 234 7.4E-42 T 28-03-2018 CDW54_RS01215 4346449eba94e21984b12846ed0076e0 256 SUPERFAMILY SSF100950 78 233 2.93E-22 T 28-03-2018 CDW54_RS01215 4346449eba94e21984b12846ed0076e0 256 Pfam PF08220 DeoR-like helix-turn-helix domain 11 60 6.3E-17 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CDW54_RS01215 4346449eba94e21984b12846ed0076e0 256 SMART SM00420 11 63 2.5E-14 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CDW54_RS01215 4346449eba94e21984b12846ed0076e0 256 Gene3D G3DSA:3.40.50.1360 76 240 1.7E-29 T 28-03-2018 CDW54_RS00270 b245c0a14c24b6fd09d1947a8ff7a0ba 1142 Gene3D G3DSA:3.30.470.20 210 450 9.8E-95 T 28-03-2018 CDW54_RS00270 b245c0a14c24b6fd09d1947a8ff7a0ba 1142 Gene3D G3DSA:3.10.600.10 459 522 4.2E-17 T 28-03-2018 CDW54_RS00270 b245c0a14c24b6fd09d1947a8ff7a0ba 1142 Pfam PF02785 Biotin carboxylase C-terminal domain 340 447 5.4E-36 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CDW54_RS00270 b245c0a14c24b6fd09d1947a8ff7a0ba 1142 SUPERFAMILY SSF51230 1064 1139 6.15E-20 T 28-03-2018 IPR011053 Single hybrid motif CDW54_RS00270 b245c0a14c24b6fd09d1947a8ff7a0ba 1142 Gene3D G3DSA:3.30.1490.20 124 209 4.4E-20 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CDW54_RS00270 b245c0a14c24b6fd09d1947a8ff7a0ba 1142 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 321 5.1E-77 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CDW54_RS00270 b245c0a14c24b6fd09d1947a8ff7a0ba 1142 SUPERFAMILY SSF89000 828 1004 9.42E-57 T 28-03-2018 CDW54_RS00270 b245c0a14c24b6fd09d1947a8ff7a0ba 1142 Gene3D G3DSA:3.10.600.10 985 1056 6.7E-21 T 28-03-2018 CDW54_RS00270 b245c0a14c24b6fd09d1947a8ff7a0ba 1142 Gene3D G3DSA:3.20.20.70 523 821 2.9E-66 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDW54_RS00270 b245c0a14c24b6fd09d1947a8ff7a0ba 1142 Gene3D G3DSA:1.10.10.60 939 984 5.8E-18 T 28-03-2018 CDW54_RS00270 b245c0a14c24b6fd09d1947a8ff7a0ba 1142 Pfam PF02436 Conserved carboxylase domain 823 1022 1.5E-75 T 28-03-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 CDW54_RS00270 b245c0a14c24b6fd09d1947a8ff7a0ba 1142 SUPERFAMILY SSF52440 1 111 1.08E-41 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CDW54_RS00270 b245c0a14c24b6fd09d1947a8ff7a0ba 1142 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CDW54_RS00270 b245c0a14c24b6fd09d1947a8ff7a0ba 1142 SUPERFAMILY SSF51569 520 831 1.04E-79 T 28-03-2018 CDW54_RS00270 b245c0a14c24b6fd09d1947a8ff7a0ba 1142 PIRSF PIRSF001594 1 1141 0.0 T 28-03-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 CDW54_RS00270 b245c0a14c24b6fd09d1947a8ff7a0ba 1142 Gene3D G3DSA:2.40.50.100 1069 1141 3.8E-19 T 28-03-2018 CDW54_RS00270 b245c0a14c24b6fd09d1947a8ff7a0ba 1142 SUPERFAMILY SSF56059 83 350 5.83E-68 T 28-03-2018 CDW54_RS00270 b245c0a14c24b6fd09d1947a8ff7a0ba 1142 Pfam PF00364 Biotin-requiring enzyme 1074 1138 1.3E-16 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CDW54_RS00270 b245c0a14c24b6fd09d1947a8ff7a0ba 1142 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 109 4.3E-40 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CDW54_RS00270 b245c0a14c24b6fd09d1947a8ff7a0ba 1142 SMART SM00878 340 447 4.4E-57 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CDW54_RS00270 b245c0a14c24b6fd09d1947a8ff7a0ba 1142 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 285 292 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CDW54_RS00270 b245c0a14c24b6fd09d1947a8ff7a0ba 1142 TIGRFAM TIGR01235 pyruv_carbox: pyruvate carboxylase 3 1139 0.0 T 28-03-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 CDW54_RS00270 b245c0a14c24b6fd09d1947a8ff7a0ba 1142 Pfam PF00682 HMGL-like 530 793 1.2E-25 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CDW54_RS00270 b245c0a14c24b6fd09d1947a8ff7a0ba 1142 SUPERFAMILY SSF51246 335 451 1.83E-40 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CDW54_RS00270 b245c0a14c24b6fd09d1947a8ff7a0ba 1142 Gene3D G3DSA:3.40.50.20 1 123 1.2E-46 T 28-03-2018 CDW54_RS10045 d1ac22432e0867268c6a2bb383162d21 232 Pfam PF13614 AAA domain 49 199 1.2E-14 T 28-03-2018 IPR025669 AAA domain CDW54_RS10045 d1ac22432e0867268c6a2bb383162d21 232 Gene3D G3DSA:3.40.50.300 17 230 1.4E-38 T 28-03-2018 CDW54_RS10045 d1ac22432e0867268c6a2bb383162d21 232 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 29 230 1.1E-67 T 28-03-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 CDW54_RS10045 d1ac22432e0867268c6a2bb383162d21 232 SUPERFAMILY SSF52540 49 226 3.76E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS05235 f969af88b3c5d094113f768bc12bb830 226 Gene3D G3DSA:1.10.10.10 129 226 1.7E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS05235 f969af88b3c5d094113f768bc12bb830 226 Gene3D G3DSA:3.40.50.2300 5 128 2.7E-30 T 28-03-2018 CDW54_RS05235 f969af88b3c5d094113f768bc12bb830 226 SMART SM00448 5 114 1.5E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDW54_RS05235 f969af88b3c5d094113f768bc12bb830 226 Pfam PF00072 Response regulator receiver domain 7 114 4.2E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDW54_RS05235 f969af88b3c5d094113f768bc12bb830 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 225 3.2E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDW54_RS05235 f969af88b3c5d094113f768bc12bb830 226 SUPERFAMILY SSF52172 6 185 4.98E-35 T 28-03-2018 IPR011006 CheY-like superfamily CDW54_RS05235 f969af88b3c5d094113f768bc12bb830 226 SMART SM00862 151 225 6.8E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDW54_RS06155 39c548096759704804e4187ababec523 333 PIRSF PIRSF002465 1 333 3.4E-121 T 28-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CDW54_RS06155 39c548096759704804e4187ababec523 333 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 1 330 9.2E-113 T 28-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CDW54_RS06155 39c548096759704804e4187ababec523 333 SUPERFAMILY SSF53659 1 328 8.22E-101 T 28-03-2018 CDW54_RS06155 39c548096759704804e4187ababec523 333 Pfam PF02504 Fatty acid synthesis protein 1 321 1.1E-107 T 28-03-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 CDW54_RS06155 39c548096759704804e4187ababec523 333 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 333 141.993 T 28-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CDW54_RS06155 39c548096759704804e4187ababec523 333 Gene3D G3DSA:3.40.718.10 1 333 6.6E-100 T 28-03-2018 CDW54_RS07475 f1053a9822646aaa01a6292321e06252 327 Gene3D G3DSA:3.40.50.10440 11 182 3.8E-70 T 28-03-2018 CDW54_RS07475 f1053a9822646aaa01a6292321e06252 327 TIGRFAM TIGR02363 dhaK1: dihydroxyacetone kinase, DhaK subunit 1 327 2.2E-151 T 28-03-2018 IPR012736 Dihydroxyacetone kinase DhaK, subunit 1 CDW54_RS07475 f1053a9822646aaa01a6292321e06252 327 Gene3D G3DSA:3.30.1180.20 183 327 1.9E-43 T 28-03-2018 CDW54_RS07475 f1053a9822646aaa01a6292321e06252 327 SUPERFAMILY SSF82549 10 327 3.66E-119 T 28-03-2018 CDW54_RS07475 f1053a9822646aaa01a6292321e06252 327 Pfam PF02733 Dak1 domain 17 324 2.1E-118 T 28-03-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CDW54_RS00895 70ea09fb58a06e4560e1356cbd9ff72c 419 Gene3D G3DSA:1.25.40.10 323 419 5.6E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDW54_RS00895 70ea09fb58a06e4560e1356cbd9ff72c 419 Gene3D G3DSA:1.25.40.10 187 254 1.3E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDW54_RS00895 70ea09fb58a06e4560e1356cbd9ff72c 419 Gene3D G3DSA:1.25.40.10 255 322 2.9E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDW54_RS00895 70ea09fb58a06e4560e1356cbd9ff72c 419 SUPERFAMILY SSF48452 14 162 3.67E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDW54_RS00895 70ea09fb58a06e4560e1356cbd9ff72c 419 Pfam PF14559 Tetratricopeptide repeat 218 277 1.0E-5 T 28-03-2018 CDW54_RS00895 70ea09fb58a06e4560e1356cbd9ff72c 419 SMART SM00028 172 205 6.2 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDW54_RS00895 70ea09fb58a06e4560e1356cbd9ff72c 419 SMART SM00028 206 238 87.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDW54_RS00895 70ea09fb58a06e4560e1356cbd9ff72c 419 SMART SM00028 33 66 60.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDW54_RS00895 70ea09fb58a06e4560e1356cbd9ff72c 419 SMART SM00028 239 272 250.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDW54_RS00895 70ea09fb58a06e4560e1356cbd9ff72c 419 SMART SM00028 339 372 130.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDW54_RS00895 70ea09fb58a06e4560e1356cbd9ff72c 419 SMART SM00028 135 168 260.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDW54_RS00895 70ea09fb58a06e4560e1356cbd9ff72c 419 SUPERFAMILY SSF48452 177 411 5.06E-19 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDW54_RS00895 70ea09fb58a06e4560e1356cbd9ff72c 419 Gene3D G3DSA:1.25.40.10 5 186 2.1E-20 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDW54_RS08870 fbe96511edcd8bf5aae7ad6555095d34 357 Gene3D G3DSA:3.40.50.300 1 259 2.7E-78 T 28-03-2018 CDW54_RS08870 fbe96511edcd8bf5aae7ad6555095d34 357 SUPERFAMILY SSF52540 1 240 9.74E-83 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS08870 fbe96511edcd8bf5aae7ad6555095d34 357 SUPERFAMILY SSF55021 256 342 1.14E-20 T 28-03-2018 CDW54_RS08870 fbe96511edcd8bf5aae7ad6555095d34 357 Pfam PF09383 NIL domain 269 338 8.1E-20 T 28-03-2018 IPR018449 NIL domain CDW54_RS08870 fbe96511edcd8bf5aae7ad6555095d34 357 Pfam PF00005 ABC transporter 22 169 3.1E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS08870 fbe96511edcd8bf5aae7ad6555095d34 357 Gene3D G3DSA:3.30.70.260 260 343 1.3E-21 T 28-03-2018 CDW54_RS08870 fbe96511edcd8bf5aae7ad6555095d34 357 SMART SM00930 266 341 3.6E-23 T 28-03-2018 IPR018449 NIL domain CDW54_RS08870 fbe96511edcd8bf5aae7ad6555095d34 357 SMART SM00382 30 233 2.9E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS08870 fbe96511edcd8bf5aae7ad6555095d34 357 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS06380 3afb94e083a8aa95125da77cfe2befc1 662 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 29 110 7.7E-15 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CDW54_RS06380 3afb94e083a8aa95125da77cfe2befc1 662 Gene3D G3DSA:2.70.70.10 501 660 2.3E-50 T 28-03-2018 CDW54_RS06380 3afb94e083a8aa95125da77cfe2befc1 662 Pfam PF02378 Phosphotransferase system, EIIC 111 408 2.9E-39 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CDW54_RS06380 3afb94e083a8aa95125da77cfe2befc1 662 Pfam PF00367 phosphotransferase system, EIIB 10 42 3.8E-12 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CDW54_RS06380 3afb94e083a8aa95125da77cfe2befc1 662 SUPERFAMILY SSF51261 509 653 1.67E-46 T 28-03-2018 IPR011055 Duplicated hybrid motif CDW54_RS06380 3afb94e083a8aa95125da77cfe2befc1 662 SUPERFAMILY SSF55604 8 80 4.45E-20 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CDW54_RS06380 3afb94e083a8aa95125da77cfe2befc1 662 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 513 637 2.3E-45 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CDW54_RS06380 3afb94e083a8aa95125da77cfe2befc1 662 TIGRFAM TIGR01992 PTS-IIBC-Tre: PTS system, trehalose-specific IIBC component 6 464 5.3E-213 T 28-03-2018 IPR011296 Phosphotransferase system, trehalose-specific IIBC component GO:0015574|GO:0015771|GO:0016021 KEGG: 00230+2.7.1.20|KEGG: 00500+2.7.1.201|MetaCyc: PWY-6619 CDW54_RS06380 3afb94e083a8aa95125da77cfe2befc1 662 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 20 37 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CDW54_RS06380 3afb94e083a8aa95125da77cfe2befc1 662 Gene3D G3DSA:3.30.1360.60 3 77 3.6E-25 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CDW54_RS06380 3afb94e083a8aa95125da77cfe2befc1 662 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 515 634 7.9E-38 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CDW54_RS06380 3afb94e083a8aa95125da77cfe2befc1 662 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 576 588 - T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CDW54_RS09790 735bb85a5952b74bc6f862b800ddd436 268 SUPERFAMILY SSF52540 13 256 2.43E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS09790 735bb85a5952b74bc6f862b800ddd436 268 SMART SM00382 46 248 2.3E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS09790 735bb85a5952b74bc6f862b800ddd436 268 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS09790 735bb85a5952b74bc6f862b800ddd436 268 Pfam PF00005 ABC transporter 38 192 3.7E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS09790 735bb85a5952b74bc6f862b800ddd436 268 Gene3D G3DSA:3.40.50.300 18 265 1.2E-59 T 28-03-2018 CDW54_RS09790 735bb85a5952b74bc6f862b800ddd436 268 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 23 268 2.3E-124 T 28-03-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 CDW54_RS00740 59eae6ba9a48f45a13dc3c4cab405378 263 SUPERFAMILY SSF46785 172 260 4.66E-40 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS00740 59eae6ba9a48f45a13dc3c4cab405378 263 Gene3D G3DSA:1.10.10.10 165 261 1.7E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS00740 59eae6ba9a48f45a13dc3c4cab405378 263 Pfam PF08222 CodY helix-turn-helix domain 203 260 5.5E-36 T 28-03-2018 IPR013198 GTP-sensing helix-turn-helix, CodY, C-terminal CDW54_RS00740 59eae6ba9a48f45a13dc3c4cab405378 263 TIGRFAM TIGR02787 codY_Gpos: GTP-sensing transcriptional pleiotropic repressor CodY 4 258 2.1E-117 T 28-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 CDW54_RS00740 59eae6ba9a48f45a13dc3c4cab405378 263 Gene3D G3DSA:3.30.450.40 1 164 2.2E-24 T 28-03-2018 IPR029016 GAF domain-like CDW54_RS00740 59eae6ba9a48f45a13dc3c4cab405378 263 PIRSF PIRSF011572 1 262 2.1E-113 T 28-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 CDW54_RS00740 59eae6ba9a48f45a13dc3c4cab405378 263 Pfam PF06018 CodY GAF-like domain 4 183 3.6E-67 T 28-03-2018 IPR010312 GTP-sensing transcriptional pleiotropic repressor CodY, N-terminal GO:0003677|GO:0005525 CDW54_RS00740 59eae6ba9a48f45a13dc3c4cab405378 263 Hamap MF_00621 GTP-sensing transcriptional pleiotropic repressor CodY [codY]. 1 263 120.148 T 28-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 CDW54_RS10020 8c8540f68f34bb875c78867af03af867 305 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 80 100 7.2E-67 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CDW54_RS10020 8c8540f68f34bb875c78867af03af867 305 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 245 261 7.2E-67 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CDW54_RS10020 8c8540f68f34bb875c78867af03af867 305 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 137 157 7.2E-67 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CDW54_RS10020 8c8540f68f34bb875c78867af03af867 305 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 160 175 7.2E-67 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CDW54_RS10020 8c8540f68f34bb875c78867af03af867 305 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 59 74 7.2E-67 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CDW54_RS10020 8c8540f68f34bb875c78867af03af867 305 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 111 135 7.2E-67 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CDW54_RS10020 8c8540f68f34bb875c78867af03af867 305 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 6 293 1.5E-158 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CDW54_RS10020 8c8540f68f34bb875c78867af03af867 305 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 7 284 1.0E-146 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CDW54_RS10020 8c8540f68f34bb875c78867af03af867 305 Gene3D G3DSA:1.20.58.180 210 286 2.7E-34 T 28-03-2018 CDW54_RS10020 8c8540f68f34bb875c78867af03af867 305 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 5 285 57.505 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CDW54_RS10020 8c8540f68f34bb875c78867af03af867 305 SUPERFAMILY SSF55681 6 284 3.48E-131 T 28-03-2018 CDW54_RS10020 8c8540f68f34bb875c78867af03af867 305 Gene3D G3DSA:3.30.930.10 1 208 4.0E-83 T 28-03-2018 CDW54_RS03930 609bd13c1e45e803a76725e47f170fc0 219 PIRSF PIRSF000709 1 186 7.6E-9 T 28-03-2018 CDW54_RS03930 609bd13c1e45e803a76725e47f170fc0 219 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 191 7.8E-45 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CDW54_RS03930 609bd13c1e45e803a76725e47f170fc0 219 SMART SM00855 2 161 1.1E-17 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CDW54_RS03930 609bd13c1e45e803a76725e47f170fc0 219 SUPERFAMILY SSF53254 1 211 2.54E-46 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CDW54_RS03930 609bd13c1e45e803a76725e47f170fc0 219 Gene3D G3DSA:3.40.50.1240 1 215 1.2E-40 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CDW54_RS07920 0844085de7b0d08e0646c86a2a38cdc2 231 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 160 194 1.9E-9 T 28-03-2018 IPR001451 Hexapeptide repeat CDW54_RS07920 0844085de7b0d08e0646c86a2a38cdc2 231 Gene3D G3DSA:3.30.70.250 1 77 3.3E-28 T 28-03-2018 CDW54_RS07920 0844085de7b0d08e0646c86a2a38cdc2 231 Pfam PF08503 Tetrahydrodipicolinate succinyltransferase N-terminal 2 82 2.6E-28 T 28-03-2018 IPR013710 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, N-terminal GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 CDW54_RS07920 0844085de7b0d08e0646c86a2a38cdc2 231 SUPERFAMILY SSF51161 84 224 2.08E-48 T 28-03-2018 IPR011004 Trimeric LpxA-like CDW54_RS07920 0844085de7b0d08e0646c86a2a38cdc2 231 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 116 151 5.3E-11 T 28-03-2018 IPR001451 Hexapeptide repeat CDW54_RS07920 0844085de7b0d08e0646c86a2a38cdc2 231 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 86 113 6.9E-4 T 28-03-2018 IPR001451 Hexapeptide repeat CDW54_RS07920 0844085de7b0d08e0646c86a2a38cdc2 231 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 169 197 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CDW54_RS07920 0844085de7b0d08e0646c86a2a38cdc2 231 TIGRFAM TIGR03532 DapD_Ac: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase 3 231 1.1E-100 T 28-03-2018 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 CDW54_RS07920 0844085de7b0d08e0646c86a2a38cdc2 231 Gene3D G3DSA:2.160.10.10 78 227 3.4E-40 T 28-03-2018 CDW54_RS01250 e99984f1095021868c3290b7a09933af 441 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 195 416 3.3E-40 T 28-03-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 CDW54_RS01250 e99984f1095021868c3290b7a09933af 441 Gene3D G3DSA:3.90.1820.10 1 271 2.0E-53 T 28-03-2018 CDW54_RS01250 e99984f1095021868c3290b7a09933af 441 Gene3D G3DSA:3.90.1820.10 272 441 6.5E-45 T 28-03-2018 CDW54_RS01250 e99984f1095021868c3290b7a09933af 441 SUPERFAMILY SSF51735 5 165 3.07E-50 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS01250 e99984f1095021868c3290b7a09933af 441 Pfam PF02056 Family 4 glycosyl hydrolase 6 181 2.9E-55 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CDW54_RS01250 e99984f1095021868c3290b7a09933af 441 SUPERFAMILY SSF56327 170 441 1.09E-78 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CDW54_RS01250 e99984f1095021868c3290b7a09933af 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 165 176 2.2E-43 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CDW54_RS01250 e99984f1095021868c3290b7a09933af 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 75 91 2.2E-43 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CDW54_RS01250 e99984f1095021868c3290b7a09933af 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 191 203 2.2E-43 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CDW54_RS01250 e99984f1095021868c3290b7a09933af 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 110 130 2.2E-43 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CDW54_RS01250 e99984f1095021868c3290b7a09933af 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 96 109 2.2E-43 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CDW54_RS01250 e99984f1095021868c3290b7a09933af 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 139 156 2.2E-43 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CDW54_RS01250 e99984f1095021868c3290b7a09933af 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 5 20 2.2E-43 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CDW54_RS00545 304939fd8b3348668409492fc43e662e 339 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 299 9.2E-49 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CDW54_RS00545 304939fd8b3348668409492fc43e662e 339 Gene3D G3DSA:3.40.50.720 116 302 1.9E-44 T 28-03-2018 CDW54_RS00545 304939fd8b3348668409492fc43e662e 339 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 147 174 - T 28-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CDW54_RS00545 304939fd8b3348668409492fc43e662e 339 SUPERFAMILY SSF51735 101 300 3.3E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS00545 304939fd8b3348668409492fc43e662e 339 SUPERFAMILY SSF52283 2 135 7.18E-32 T 28-03-2018 CDW54_RS00545 304939fd8b3348668409492fc43e662e 339 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 7 330 5.6E-25 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CDW54_RS00545 304939fd8b3348668409492fc43e662e 339 Gene3D G3DSA:3.40.50.720 1 115 3.1E-20 T 28-03-2018 CDW54_RS08920 eb02b0f3d9018b32dacc1f0fbdc72471 373 PIRSF PIRSF006078 1 370 2.7E-95 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CDW54_RS08920 eb02b0f3d9018b32dacc1f0fbdc72471 373 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 3 354 1.3E-89 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CDW54_RS08920 eb02b0f3d9018b32dacc1f0fbdc72471 373 Gene3D G3DSA:3.90.1510.10 40 270 1.0E-56 T 28-03-2018 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 CDW54_RS08920 eb02b0f3d9018b32dacc1f0fbdc72471 373 SUPERFAMILY SSF110738 1 353 2.09E-91 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CDW54_RS08920 eb02b0f3d9018b32dacc1f0fbdc72471 373 Pfam PF02595 Glycerate kinase family 3 354 4.0E-93 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CDW54_RS06205 518aa7429a2af72adf8d87dcb497aaaa 269 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 263 8.9E-67 T 28-03-2018 IPR000150 Cof family GO:0016787 CDW54_RS06205 518aa7429a2af72adf8d87dcb497aaaa 269 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 263 3.0E-68 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS06205 518aa7429a2af72adf8d87dcb497aaaa 269 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 236 2.4E-31 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CDW54_RS06205 518aa7429a2af72adf8d87dcb497aaaa 269 SUPERFAMILY SSF56784 1 268 1.77E-73 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS06205 518aa7429a2af72adf8d87dcb497aaaa 269 Gene3D G3DSA:3.40.50.1000 1 269 2.4E-46 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS06205 518aa7429a2af72adf8d87dcb497aaaa 269 ProSitePatterns PS01228 Hypothetical cof family signature 1. 4 15 - T 28-03-2018 CDW54_RS11720 54574a6fbc4567e50317a6af6564c9be 66 SMART SM00357 3 66 1.7E-30 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CDW54_RS11720 54574a6fbc4567e50317a6af6564c9be 66 PIRSF PIRSF002599 1 66 6.2E-23 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 CDW54_RS11720 54574a6fbc4567e50317a6af6564c9be 66 SUPERFAMILY SSF50249 1 64 4.16E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDW54_RS11720 54574a6fbc4567e50317a6af6564c9be 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 3.8E-30 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CDW54_RS11720 54574a6fbc4567e50317a6af6564c9be 66 PRINTS PR00050 Cold shock protein signature 4 19 6.8E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CDW54_RS11720 54574a6fbc4567e50317a6af6564c9be 66 PRINTS PR00050 Cold shock protein signature 39 57 6.8E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CDW54_RS11720 54574a6fbc4567e50317a6af6564c9be 66 PRINTS PR00050 Cold shock protein signature 24 33 6.8E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CDW54_RS11720 54574a6fbc4567e50317a6af6564c9be 66 Gene3D G3DSA:2.40.50.140 1 66 7.9E-27 T 28-03-2018 CDW54_RS11720 54574a6fbc4567e50317a6af6564c9be 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 28-03-2018 IPR019844 Cold-shock conserved site CDW54_RS02110 264abd8b61a9035d2bbd5ba19f46a2b1 560 Gene3D G3DSA:3.40.50.300 239 531 2.3E-18 T 28-03-2018 CDW54_RS02110 264abd8b61a9035d2bbd5ba19f46a2b1 560 Pfam PF02463 RecF/RecN/SMC N terminal domain 1 510 1.0E-14 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CDW54_RS02110 264abd8b61a9035d2bbd5ba19f46a2b1 560 SUPERFAMILY SSF52540 1 220 4.49E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS02110 264abd8b61a9035d2bbd5ba19f46a2b1 560 Gene3D G3DSA:3.40.50.300 1 233 1.9E-26 T 28-03-2018 CDW54_RS02110 264abd8b61a9035d2bbd5ba19f46a2b1 560 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 555 1.8E-173 T 28-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 CDW54_RS02110 264abd8b61a9035d2bbd5ba19f46a2b1 560 SUPERFAMILY SSF52540 4 50 1.46E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS02110 264abd8b61a9035d2bbd5ba19f46a2b1 560 SUPERFAMILY SSF52540 296 508 1.46E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS02110 264abd8b61a9035d2bbd5ba19f46a2b1 560 PIRSF PIRSF003128 1 560 2.5E-174 T 28-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 CDW54_RS01580 9b725f620b0141329c8652ccfbd8d4a7 321 SUPERFAMILY SSF82771 11 92 7.06E-22 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CDW54_RS01580 9b725f620b0141329c8652ccfbd8d4a7 321 Gene3D G3DSA:3.40.1440.10 1 95 1.7E-23 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CDW54_RS01580 9b725f620b0141329c8652ccfbd8d4a7 321 Pfam PF01541 GIY-YIG catalytic domain 14 89 9.1E-10 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CDW54_RS01580 9b725f620b0141329c8652ccfbd8d4a7 321 SMART SM00465 12 94 4.1E-16 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CDW54_RS03455 a185d16f783b5a5dbe200111b9f86332 316 SUPERFAMILY SSF51182 1 312 9.57E-109 T 28-03-2018 IPR011051 RmlC-like cupin domain CDW54_RS03455 a185d16f783b5a5dbe200111b9f86332 316 Gene3D G3DSA:2.60.120.10 226 313 1.2E-15 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CDW54_RS03455 a185d16f783b5a5dbe200111b9f86332 316 Gene3D G3DSA:2.60.120.10 1 222 1.3E-63 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CDW54_RS03455 a185d16f783b5a5dbe200111b9f86332 316 Pfam PF01238 Phosphomannose isomerase type I 5 198 3.4E-42 T 28-03-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CDW54_RS03455 a185d16f783b5a5dbe200111b9f86332 316 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 104 311 7.3E-47 T 28-03-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CDW54_RS03455 a185d16f783b5a5dbe200111b9f86332 316 PIRSF PIRSF036894 2 315 3.2E-133 T 28-03-2018 IPR014628 Mannose-6-phosphate isomerase, Firmicutes type, short form GO:0004476|GO:0005975 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 CDW54_RS05020 34ebccc58479498150b95135f5a14b09 413 Hamap MF_00226_B Putative competence-damage inducible protein [cinA]. 1 413 152.388 T 28-03-2018 IPR008135 Competence-induced protein CinA CDW54_RS05020 34ebccc58479498150b95135f5a14b09 413 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 265 410 3.5E-38 T 28-03-2018 IPR008136 CinA, C-terminal CDW54_RS05020 34ebccc58479498150b95135f5a14b09 413 Pfam PF00994 Probable molybdopterin binding domain 4 169 1.5E-29 T 28-03-2018 IPR001453 MoaB/Mog domain CDW54_RS05020 34ebccc58479498150b95135f5a14b09 413 Gene3D G3DSA:3.90.950.20 249 413 2.6E-51 T 28-03-2018 CDW54_RS05020 34ebccc58479498150b95135f5a14b09 413 Gene3D G3DSA:3.40.980.10 1 171 4.0E-38 T 28-03-2018 IPR001453 MoaB/Mog domain CDW54_RS05020 34ebccc58479498150b95135f5a14b09 413 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 1 164 2.8E-26 T 28-03-2018 IPR001453 MoaB/Mog domain CDW54_RS05020 34ebccc58479498150b95135f5a14b09 413 Pfam PF02464 Competence-damaged protein 258 410 9.0E-50 T 28-03-2018 IPR008136 CinA, C-terminal CDW54_RS05020 34ebccc58479498150b95135f5a14b09 413 SUPERFAMILY SSF142433 252 411 9.81E-48 T 28-03-2018 IPR008136 CinA, C-terminal CDW54_RS05020 34ebccc58479498150b95135f5a14b09 413 SMART SM00852 4 171 2.3E-35 T 28-03-2018 IPR001453 MoaB/Mog domain CDW54_RS05020 34ebccc58479498150b95135f5a14b09 413 SUPERFAMILY SSF53218 1 191 1.09E-35 T 28-03-2018 IPR001453 MoaB/Mog domain CDW54_RS05020 34ebccc58479498150b95135f5a14b09 413 PIRSF PIRSF006728 1 413 2.3E-147 T 28-03-2018 IPR008135 Competence-induced protein CinA CDW54_RS05020 34ebccc58479498150b95135f5a14b09 413 TIGRFAM TIGR00200 cinA_nterm: competence/damage-inducible protein CinA N-terminal domain 1 410 2.5E-126 T 28-03-2018 IPR008135 Competence-induced protein CinA CDW54_RS00750 a72a03ab65cc04da8b4c5e64de080c94 182 Pfam PF00227 Proteasome subunit 7 180 2.1E-24 T 28-03-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 CDW54_RS00750 a72a03ab65cc04da8b4c5e64de080c94 182 Gene3D G3DSA:3.60.20.10 9 182 1.9E-28 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CDW54_RS00750 a72a03ab65cc04da8b4c5e64de080c94 182 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 9 182 8.5E-82 T 28-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 CDW54_RS00750 a72a03ab65cc04da8b4c5e64de080c94 182 SUPERFAMILY SSF56235 6 181 3.46E-58 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CDW54_RS00750 a72a03ab65cc04da8b4c5e64de080c94 182 PIRSF PIRSF039093 2 182 3.6E-80 T 28-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 CDW54_RS00750 a72a03ab65cc04da8b4c5e64de080c94 182 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 8 182 40.131 T 28-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 CDW54_RS09050 6a04762778ab1b870ea7b729cc273bb8 226 SMART SM00986 50 210 8.3E-39 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CDW54_RS09050 6a04762778ab1b870ea7b729cc273bb8 226 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 6 221 41.467 T 28-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CDW54_RS09050 6a04762778ab1b870ea7b729cc273bb8 226 Gene3D G3DSA:3.40.470.10 1 226 1.4E-102 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CDW54_RS09050 6a04762778ab1b870ea7b729cc273bb8 226 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 7 210 3.5E-82 T 28-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CDW54_RS09050 6a04762778ab1b870ea7b729cc273bb8 226 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 58 67 - T 28-03-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CDW54_RS09050 6a04762778ab1b870ea7b729cc273bb8 226 SUPERFAMILY SSF52141 3 222 4.8E-95 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CDW54_RS09050 6a04762778ab1b870ea7b729cc273bb8 226 Pfam PF03167 Uracil DNA glycosylase superfamily 54 207 2.2E-23 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CDW54_RS09050 6a04762778ab1b870ea7b729cc273bb8 226 SMART SM00987 50 210 8.3E-39 T 28-03-2018 CDW54_RS04820 65692cd9e0b638f9582f2d2866bc3709 1173 SUPERFAMILY SSF52540 542 801 2.62E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS04820 65692cd9e0b638f9582f2d2866bc3709 1173 SUPERFAMILY SSF141259 489 566 3.66E-25 T 28-03-2018 IPR003711 CarD-like/TRCF domain CDW54_RS04820 65692cd9e0b638f9582f2d2866bc3709 1173 SMART SM00982 1022 1122 2.4E-35 T 28-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CDW54_RS04820 65692cd9e0b638f9582f2d2866bc3709 1173 Gene3D G3DSA:3.40.50.300 807 974 1.5E-23 T 28-03-2018 CDW54_RS04820 65692cd9e0b638f9582f2d2866bc3709 1173 Pfam PF00271 Helicase conserved C-terminal domain 825 927 5.5E-14 T 28-03-2018 IPR001650 Helicase, C-terminal CDW54_RS04820 65692cd9e0b638f9582f2d2866bc3709 1173 SUPERFAMILY SSF143517 1009 1160 7.32E-32 T 28-03-2018 CDW54_RS04820 65692cd9e0b638f9582f2d2866bc3709 1173 SMART SM00490 844 928 1.3E-15 T 28-03-2018 IPR001650 Helicase, C-terminal CDW54_RS04820 65692cd9e0b638f9582f2d2866bc3709 1173 SMART SM01058 497 594 4.7E-51 T 28-03-2018 IPR003711 CarD-like/TRCF domain CDW54_RS04820 65692cd9e0b638f9582f2d2866bc3709 1173 Pfam PF02559 CarD-like/TRCF domain 498 593 3.2E-31 T 28-03-2018 IPR003711 CarD-like/TRCF domain CDW54_RS04820 65692cd9e0b638f9582f2d2866bc3709 1173 Gene3D G3DSA:3.40.50.300 452 792 1.5E-39 T 28-03-2018 CDW54_RS04820 65692cd9e0b638f9582f2d2866bc3709 1173 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 36 1126 29.378 T 28-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 CDW54_RS04820 65692cd9e0b638f9582f2d2866bc3709 1173 SUPERFAMILY SSF52540 13 369 2.22E-83 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS04820 65692cd9e0b638f9582f2d2866bc3709 1173 Pfam PF03461 TRCF domain 1023 1109 2.4E-24 T 28-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CDW54_RS04820 65692cd9e0b638f9582f2d2866bc3709 1173 Gene3D G3DSA:3.40.50.300 3 440 7.8E-6 T 28-03-2018 CDW54_RS04820 65692cd9e0b638f9582f2d2866bc3709 1173 SUPERFAMILY SSF52540 800 1005 1.52E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS04820 65692cd9e0b638f9582f2d2866bc3709 1173 SMART SM00487 618 808 2.1E-36 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CDW54_RS04820 65692cd9e0b638f9582f2d2866bc3709 1173 SUPERFAMILY SSF52540 377 488 1.36E-21 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS04820 65692cd9e0b638f9582f2d2866bc3709 1173 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 157 1090 0.0 T 28-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 CDW54_RS04820 65692cd9e0b638f9582f2d2866bc3709 1173 Pfam PF00270 DEAD/DEAH box helicase 643 782 3.3E-17 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CDW54_RS08320 af3a0a6fc78ce5c11386b004878b0e99 344 SMART SM00382 32 220 1.2E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS08320 af3a0a6fc78ce5c11386b004878b0e99 344 Pfam PF09383 NIL domain 269 340 4.6E-18 T 28-03-2018 IPR018449 NIL domain CDW54_RS08320 af3a0a6fc78ce5c11386b004878b0e99 344 SMART SM00930 266 341 1.8E-24 T 28-03-2018 IPR018449 NIL domain CDW54_RS08320 af3a0a6fc78ce5c11386b004878b0e99 344 Pfam PF00005 ABC transporter 24 171 6.9E-37 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS08320 af3a0a6fc78ce5c11386b004878b0e99 344 Gene3D G3DSA:3.30.70.260 263 343 2.9E-24 T 28-03-2018 CDW54_RS08320 af3a0a6fc78ce5c11386b004878b0e99 344 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS08320 af3a0a6fc78ce5c11386b004878b0e99 344 SUPERFAMILY SSF52540 3 242 3.5E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS08320 af3a0a6fc78ce5c11386b004878b0e99 344 SUPERFAMILY SSF55021 255 342 1.37E-20 T 28-03-2018 CDW54_RS08320 af3a0a6fc78ce5c11386b004878b0e99 344 Gene3D G3DSA:3.40.50.300 1 262 1.5E-77 T 28-03-2018 CDW54_RS10745 696fb3b376f1be216401011ce1548367 494 TIGRFAM TIGR01239 galT_2: galactose-1-phosphate uridylyltransferase 8 492 2.8E-226 T 28-03-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CDW54_RS10745 696fb3b376f1be216401011ce1548367 494 Hamap MF_00571 Galactose-1-phosphate uridylyltransferase [galT]. 1 494 268.692 T 28-03-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CDW54_RS10745 696fb3b376f1be216401011ce1548367 494 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 248 440 1.3E-36 T 28-03-2018 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 CDW54_RS10745 696fb3b376f1be216401011ce1548367 494 PIRSF PIRSF006005 1 494 5.8E-231 T 28-03-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CDW54_RS10745 696fb3b376f1be216401011ce1548367 494 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 22 230 2.2E-37 T 28-03-2018 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 CDW54_RS10745 696fb3b376f1be216401011ce1548367 494 ProSitePatterns PS01163 Galactose-1-phosphate uridyl transferase family 2 signature. 258 275 - T 28-03-2018 IPR023425 Galactose-1-phosphate uridyl transferase, class II, conserved site GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CDW54_RS06385 2ec25f8c669431ded8d4c7f5e3b68a62 237 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 66 8.9E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDW54_RS06385 2ec25f8c669431ded8d4c7f5e3b68a62 237 SUPERFAMILY SSF46785 3 70 4.03E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS06385 2ec25f8c669431ded8d4c7f5e3b68a62 237 TIGRFAM TIGR02404 trehalos_R_Bsub: trehalose operon repressor 3 234 1.5E-94 T 28-03-2018 IPR012770 Trehalose operon transcriptional repressor CDW54_RS06385 2ec25f8c669431ded8d4c7f5e3b68a62 237 SUPERFAMILY SSF64288 54 234 2.2E-37 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CDW54_RS06385 2ec25f8c669431ded8d4c7f5e3b68a62 237 Pfam PF07702 UTRA domain 93 227 6.0E-29 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CDW54_RS06385 2ec25f8c669431ded8d4c7f5e3b68a62 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 1.0E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDW54_RS06385 2ec25f8c669431ded8d4c7f5e3b68a62 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 1.0E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDW54_RS06385 2ec25f8c669431ded8d4c7f5e3b68a62 237 SMART SM00345 7 66 6.4E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDW54_RS06385 2ec25f8c669431ded8d4c7f5e3b68a62 237 SMART SM00866 88 227 1.7E-22 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CDW54_RS06385 2ec25f8c669431ded8d4c7f5e3b68a62 237 Gene3D G3DSA:1.10.10.10 1 67 4.2E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS06385 2ec25f8c669431ded8d4c7f5e3b68a62 237 Gene3D G3DSA:3.40.1410.10 70 237 1.5E-28 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CDW54_RS07325 9b026132ed920c6ac77b2bbe0bd62c91 540 Pfam PF00128 Alpha amylase, catalytic domain 28 362 2.1E-126 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CDW54_RS07325 9b026132ed920c6ac77b2bbe0bd62c91 540 Gene3D G3DSA:2.60.40.1180 489 539 6.9E-14 T 28-03-2018 CDW54_RS07325 9b026132ed920c6ac77b2bbe0bd62c91 540 SUPERFAMILY SSF51011 466 538 1.29E-17 T 28-03-2018 CDW54_RS07325 9b026132ed920c6ac77b2bbe0bd62c91 540 Pfam PF16657 Maltogenic Amylase, C-terminal domain 466 535 8.9E-9 T 28-03-2018 IPR032091 Maltogenic Amylase, C-terminal CDW54_RS07325 9b026132ed920c6ac77b2bbe0bd62c91 540 Gene3D G3DSA:3.20.20.80 1 248 4.6E-72 T 28-03-2018 CDW54_RS07325 9b026132ed920c6ac77b2bbe0bd62c91 540 Gene3D G3DSA:3.20.20.80 249 488 1.2E-65 T 28-03-2018 CDW54_RS07325 9b026132ed920c6ac77b2bbe0bd62c91 540 SMART SM00642 13 405 3.2E-157 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CDW54_RS07325 9b026132ed920c6ac77b2bbe0bd62c91 540 SUPERFAMILY SSF51445 3 463 1.72E-153 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CDW54_RS05955 406c7eb934d7113fa067cdec16350bde 144 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 1.2E-57 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS05955 406c7eb934d7113fa067cdec16350bde 144 Gene3D G3DSA:3.90.1170.10 3 139 1.3E-50 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CDW54_RS05955 406c7eb934d7113fa067cdec16350bde 144 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 28-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS05955 406c7eb934d7113fa067cdec16350bde 144 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 38.448 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS05955 406c7eb934d7113fa067cdec16350bde 144 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 28-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS05955 406c7eb934d7113fa067cdec16350bde 144 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 5.7E-49 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CDW54_RS05955 406c7eb934d7113fa067cdec16350bde 144 SUPERFAMILY SSF54686 1 137 2.35E-55 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CDW54_RS05955 406c7eb934d7113fa067cdec16350bde 144 PRINTS PR00060 Ribosomal protein L16 signature 58 87 3.3E-37 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS05955 406c7eb934d7113fa067cdec16350bde 144 PRINTS PR00060 Ribosomal protein L16 signature 24 36 3.3E-37 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS05955 406c7eb934d7113fa067cdec16350bde 144 PRINTS PR00060 Ribosomal protein L16 signature 88 117 3.3E-37 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS05955 406c7eb934d7113fa067cdec16350bde 144 PRINTS PR00060 Ribosomal protein L16 signature 42 53 3.3E-37 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS05905 891bb953b463430c7d75626c04d5ed93 695 Gene3D G3DSA:3.30.230.10 490 611 1.2E-44 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CDW54_RS05905 891bb953b463430c7d75626c04d5ed93 695 Pfam PF00679 Elongation factor G C-terminus 598 685 2.3E-32 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CDW54_RS05905 891bb953b463430c7d75626c04d5ed93 695 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CDW54_RS05905 891bb953b463430c7d75626c04d5ed93 695 SUPERFAMILY SSF54211 477 597 5.56E-44 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CDW54_RS05905 891bb953b463430c7d75626c04d5ed93 695 Pfam PF03764 Elongation factor G, domain IV 477 596 1.6E-46 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CDW54_RS05905 891bb953b463430c7d75626c04d5ed93 695 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 179 1.6E-42 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CDW54_RS05905 891bb953b463430c7d75626c04d5ed93 695 Gene3D G3DSA:3.30.70.240 612 690 7.1E-33 T 28-03-2018 CDW54_RS05905 891bb953b463430c7d75626c04d5ed93 695 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 690 0.0 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CDW54_RS05905 891bb953b463430c7d75626c04d5ed93 695 SUPERFAMILY SSF54980 400 478 1.65E-25 T 28-03-2018 IPR035647 EF-G domain III/V-like CDW54_RS05905 891bb953b463430c7d75626c04d5ed93 695 SMART SM00838 598 686 1.6E-54 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CDW54_RS05905 891bb953b463430c7d75626c04d5ed93 695 SUPERFAMILY SSF52540 6 280 7.9E-112 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS05905 891bb953b463430c7d75626c04d5ed93 695 Pfam PF00009 Elongation factor Tu GTP binding domain 9 280 7.3E-70 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDW54_RS05905 891bb953b463430c7d75626c04d5ed93 695 Pfam PF03144 Elongation factor Tu domain 2 322 389 7.0E-16 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CDW54_RS05905 891bb953b463430c7d75626c04d5ed93 695 Gene3D G3DSA:3.40.50.300 1 285 6.6E-65 T 28-03-2018 CDW54_RS05905 891bb953b463430c7d75626c04d5ed93 695 SUPERFAMILY SSF54980 601 689 4.36E-31 T 28-03-2018 IPR035647 EF-G domain III/V-like CDW54_RS05905 891bb953b463430c7d75626c04d5ed93 695 Gene3D G3DSA:2.40.30.10 287 399 3.5E-31 T 28-03-2018 CDW54_RS05905 891bb953b463430c7d75626c04d5ed93 695 Gene3D G3DSA:3.30.70.870 400 489 9.5E-35 T 28-03-2018 CDW54_RS05905 891bb953b463430c7d75626c04d5ed93 695 SUPERFAMILY SSF50447 263 402 1.11E-36 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CDW54_RS05905 891bb953b463430c7d75626c04d5ed93 695 SMART SM00889 478 596 1.6E-72 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CDW54_RS05905 891bb953b463430c7d75626c04d5ed93 695 Pfam PF14492 Elongation Factor G, domain II 402 475 2.7E-34 T 28-03-2018 CDW54_RS05905 891bb953b463430c7d75626c04d5ed93 695 PRINTS PR00315 GTP-binding elongation factor signature 78 88 1.8E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDW54_RS05905 891bb953b463430c7d75626c04d5ed93 695 PRINTS PR00315 GTP-binding elongation factor signature 130 139 1.8E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDW54_RS05905 891bb953b463430c7d75626c04d5ed93 695 PRINTS PR00315 GTP-binding elongation factor signature 94 105 1.8E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDW54_RS05905 891bb953b463430c7d75626c04d5ed93 695 PRINTS PR00315 GTP-binding elongation factor signature 12 25 1.8E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDW54_RS05905 891bb953b463430c7d75626c04d5ed93 695 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.8E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDW54_RS05905 891bb953b463430c7d75626c04d5ed93 695 Hamap MF_00054_B Elongation factor G [fusA]. 6 690 111.4 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CDW54_RS06465 018bbf592ffc8d9de844d874b9efd391 173 SUPERFAMILY SSF46785 5 61 2.84E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS06465 018bbf592ffc8d9de844d874b9efd391 173 Gene3D G3DSA:3.30.1340.20 71 171 1.2E-37 T 28-03-2018 IPR004173 3H domain GO:0036094 CDW54_RS06465 018bbf592ffc8d9de844d874b9efd391 173 ProDom PD469575 TRANSCRIPTION DNA-BINDING REGULATION TRANSCRIPTIONAL REGULATOR REPRESSOR FAMILY BIOTIN REGULATOR 3H 77 170 2.0E-49 T 28-03-2018 IPR004173 3H domain GO:0036094 CDW54_RS06465 018bbf592ffc8d9de844d874b9efd391 173 Gene3D G3DSA:1.10.10.10 2 63 2.6E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS06465 018bbf592ffc8d9de844d874b9efd391 173 SUPERFAMILY SSF75500 69 172 4.18E-36 T 28-03-2018 IPR004173 3H domain GO:0036094 CDW54_RS06465 018bbf592ffc8d9de844d874b9efd391 173 Pfam PF02829 3H domain 74 170 1.6E-35 T 28-03-2018 IPR004173 3H domain GO:0036094 CDW54_RS06465 018bbf592ffc8d9de844d874b9efd391 173 Pfam PF08279 HTH domain 7 60 3.2E-13 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CDW54_RS06465 018bbf592ffc8d9de844d874b9efd391 173 PIRSF PIRSF037847 2 173 6.8E-67 T 28-03-2018 IPR026043 Transcription repressor NadR CDW54_RS09665 d0dc2a7103d7c98d0b8da23d967ed81f 140 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 5 86 1.6E-27 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS09665 d0dc2a7103d7c98d0b8da23d967ed81f 140 SUPERFAMILY SSF51344 4 88 4.71E-23 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS09665 d0dc2a7103d7c98d0b8da23d967ed81f 140 Gene3D G3DSA:2.60.15.10 1 92 8.3E-25 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS09665 d0dc2a7103d7c98d0b8da23d967ed81f 140 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 5 136 2.1E-30 T 28-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS09665 d0dc2a7103d7c98d0b8da23d967ed81f 140 SUPERFAMILY SSF46604 91 138 3.92E-6 T 28-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS09665 d0dc2a7103d7c98d0b8da23d967ed81f 140 Gene3D G3DSA:1.20.5.440 93 138 4.5E-16 T 28-03-2018 CDW54_RS09665 d0dc2a7103d7c98d0b8da23d967ed81f 140 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 90 138 1.2E-15 T 28-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS09665 d0dc2a7103d7c98d0b8da23d967ed81f 140 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 24 92 1.0E-32 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS09665 d0dc2a7103d7c98d0b8da23d967ed81f 140 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 3 136 24.01 T 28-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS12195 458d37d4f31dd2d0a00d655f6e086bea 215 SUPERFAMILY SSF46689 29 88 1.44E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDW54_RS12195 458d37d4f31dd2d0a00d655f6e086bea 215 Gene3D G3DSA:1.10.10.60 28 64 8.1E-7 T 28-03-2018 CDW54_RS12195 458d37d4f31dd2d0a00d655f6e086bea 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 47 72 3.6E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDW54_RS12195 458d37d4f31dd2d0a00d655f6e086bea 215 Gene3D G3DSA:1.10.10.60 65 212 1.1E-4 T 28-03-2018 CDW54_RS11160 6f2138b55cdf23e9e7ec9738557b6f56 250 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CDW54_RS11160 6f2138b55cdf23e9e7ec9738557b6f56 250 SMART SM00420 6 58 1.4E-21 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CDW54_RS11160 6f2138b55cdf23e9e7ec9738557b6f56 250 SUPERFAMILY SSF100950 74 228 1.15E-36 T 28-03-2018 CDW54_RS11160 6f2138b55cdf23e9e7ec9738557b6f56 250 Gene3D G3DSA:3.40.50.1360 65 244 7.4E-42 T 28-03-2018 CDW54_RS11160 6f2138b55cdf23e9e7ec9738557b6f56 250 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 5.0E-9 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CDW54_RS11160 6f2138b55cdf23e9e7ec9738557b6f56 250 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 5.0E-9 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CDW54_RS11160 6f2138b55cdf23e9e7ec9738557b6f56 250 Pfam PF00455 DeoR C terminal sensor domain 75 229 2.1E-48 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain CDW54_RS11160 6f2138b55cdf23e9e7ec9738557b6f56 250 SMART SM01134 73 231 3.7E-65 T 28-03-2018 CDW54_RS11160 6f2138b55cdf23e9e7ec9738557b6f56 250 SUPERFAMILY SSF46785 4 79 1.46E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS11160 6f2138b55cdf23e9e7ec9738557b6f56 250 Gene3D G3DSA:1.10.10.10 1 58 1.9E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS11160 6f2138b55cdf23e9e7ec9738557b6f56 250 Pfam PF08220 DeoR-like helix-turn-helix domain 6 57 1.2E-17 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CDW54_RS05625 60ba8baa313c8be5bbea604c5c8b498d 387 Pfam PF14657 Arm DNA-binding domain 16 60 3.6E-16 T 28-03-2018 IPR028259 AP2-like integrase, N-terminal domain CDW54_RS05625 60ba8baa313c8be5bbea604c5c8b498d 387 Gene3D G3DSA:1.10.443.10 173 387 1.0E-36 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CDW54_RS05625 60ba8baa313c8be5bbea604c5c8b498d 387 Pfam PF00589 Phage integrase family 176 371 1.4E-24 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CDW54_RS05625 60ba8baa313c8be5bbea604c5c8b498d 387 SUPERFAMILY SSF56349 68 377 1.94E-56 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CDW54_RS05625 60ba8baa313c8be5bbea604c5c8b498d 387 Gene3D G3DSA:1.10.150.130 63 172 7.5E-16 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CDW54_RS05625 60ba8baa313c8be5bbea604c5c8b498d 387 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 68 125 4.6E-18 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CDW54_RS11715 de5c9678b4cfedae5540601cd2dadc73 255 Pfam PF13419 Haloacid dehalogenase-like hydrolase 26 202 2.0E-30 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS11715 de5c9678b4cfedae5540601cd2dadc73 255 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 144 205 2.2E-15 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDW54_RS11715 de5c9678b4cfedae5540601cd2dadc73 255 SUPERFAMILY SSF56784 23 243 5.65E-42 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS11715 de5c9678b4cfedae5540601cd2dadc73 255 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 168 188 2.7E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDW54_RS11715 de5c9678b4cfedae5540601cd2dadc73 255 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 195 208 2.7E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDW54_RS11715 de5c9678b4cfedae5540601cd2dadc73 255 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 22 33 2.7E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDW54_RS11715 de5c9678b4cfedae5540601cd2dadc73 255 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 150 166 2.7E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDW54_RS11715 de5c9678b4cfedae5540601cd2dadc73 255 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 119 132 2.7E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDW54_RS11715 de5c9678b4cfedae5540601cd2dadc73 255 Gene3D G3DSA:3.40.50.1000 22 250 1.9E-31 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS11715 de5c9678b4cfedae5540601cd2dadc73 255 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 121 200 1.5E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDW54_RS09395 0583ae9c22f2ab20e7a058b768dedf61 592 Gene3D G3DSA:3.40.1440.10 1 98 1.5E-25 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CDW54_RS09395 0583ae9c22f2ab20e7a058b768dedf61 592 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 6 571 7.2E-208 T 28-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 CDW54_RS09395 0583ae9c22f2ab20e7a058b768dedf61 592 Hamap MF_00203 UvrABC system protein C [uvrC]. 2 588 28.224 T 28-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 CDW54_RS09395 0583ae9c22f2ab20e7a058b768dedf61 592 SUPERFAMILY SSF46600 183 236 2.62E-14 T 28-03-2018 IPR001943 UVR domain GO:0005515 CDW54_RS09395 0583ae9c22f2ab20e7a058b768dedf61 592 Pfam PF02151 UvrB/uvrC motif 202 231 1.0E-9 T 28-03-2018 IPR001943 UVR domain GO:0005515 CDW54_RS09395 0583ae9c22f2ab20e7a058b768dedf61 592 Gene3D G3DSA:1.10.150.20 523 592 6.8E-12 T 28-03-2018 CDW54_RS09395 0583ae9c22f2ab20e7a058b768dedf61 592 SUPERFAMILY SSF47781 503 591 1.37E-19 T 28-03-2018 IPR010994 RuvA domain 2-like CDW54_RS09395 0583ae9c22f2ab20e7a058b768dedf61 592 Pfam PF01541 GIY-YIG catalytic domain 16 90 1.2E-9 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CDW54_RS09395 0583ae9c22f2ab20e7a058b768dedf61 592 Gene3D G3DSA:4.10.860.10 177 236 8.7E-16 T 28-03-2018 IPR001943 UVR domain GO:0005515 CDW54_RS09395 0583ae9c22f2ab20e7a058b768dedf61 592 SMART SM00465 15 95 4.6E-23 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CDW54_RS09395 0583ae9c22f2ab20e7a058b768dedf61 592 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 374 524 1.7E-55 T 28-03-2018 IPR001162 UvrC family homology region CDW54_RS09395 0583ae9c22f2ab20e7a058b768dedf61 592 SUPERFAMILY SSF82771 14 97 3.79E-21 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CDW54_RS01040 f4e81768c9d1a2b930af368dcd0786fd 863 SUPERFAMILY SSF55729 643 824 1.01E-12 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDW54_RS01040 f4e81768c9d1a2b930af368dcd0786fd 863 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 527 824 6.9E-86 T 28-03-2018 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal CDW54_RS01040 f4e81768c9d1a2b930af368dcd0786fd 863 Gene3D G3DSA:1.10.287.70 471 614 0.23 T 28-03-2018 CDW54_RS01040 f4e81768c9d1a2b930af368dcd0786fd 863 Gene3D G3DSA:3.40.630.30 624 817 8.4E-14 T 28-03-2018 CDW54_RS01040 f4e81768c9d1a2b930af368dcd0786fd 863 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 37 294 1.2E-6 T 28-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD CDW54_RS02525 a95dc71152be53f856b25b08c66712c0 586 Gene3D G3DSA:1.20.1560.10 1 317 2.1E-74 T 28-03-2018 CDW54_RS02525 a95dc71152be53f856b25b08c66712c0 586 Pfam PF00005 ABC transporter 362 510 3.1E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS02525 a95dc71152be53f856b25b08c66712c0 586 Pfam PF00664 ABC transporter transmembrane region 23 299 3.7E-48 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CDW54_RS02525 a95dc71152be53f856b25b08c66712c0 586 SUPERFAMILY SSF52540 339 581 4.39E-89 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS02525 a95dc71152be53f856b25b08c66712c0 586 SUPERFAMILY SSF90123 9 328 1.12E-76 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CDW54_RS02525 a95dc71152be53f856b25b08c66712c0 586 ProSitePatterns PS00211 ABC transporters family signature. 482 496 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS02525 a95dc71152be53f856b25b08c66712c0 586 SMART SM00382 370 562 1.3E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS02525 a95dc71152be53f856b25b08c66712c0 586 Gene3D G3DSA:3.40.50.300 318 586 7.8E-72 T 28-03-2018 CDW54_RS07480 da04c59a1e4dbb880581f8766a60d6cc 201 TIGRFAM TIGR02365 dha_L_ycgS: dihydroxyacetone kinase, L subunit 8 195 3.1E-73 T 28-03-2018 IPR012737 Dihydroxyacetone kinase, subunit L GO:0016772 CDW54_RS07480 da04c59a1e4dbb880581f8766a60d6cc 201 SMART SM01120 32 196 5.0E-64 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CDW54_RS07480 da04c59a1e4dbb880581f8766a60d6cc 201 SUPERFAMILY SSF101473 3 198 2.09E-56 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CDW54_RS07480 da04c59a1e4dbb880581f8766a60d6cc 201 Pfam PF02734 DAK2 domain 32 195 1.6E-49 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CDW54_RS11165 31ee1622135bcce9406216937f9f444a 304 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 301 7.1E-108 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CDW54_RS11165 31ee1622135bcce9406216937f9f444a 304 PIRSF PIRSF000535 1 303 2.1E-87 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CDW54_RS11165 31ee1622135bcce9406216937f9f444a 304 SUPERFAMILY SSF53613 1 281 4.05E-67 T 28-03-2018 IPR029056 Ribokinase-like CDW54_RS11165 31ee1622135bcce9406216937f9f444a 304 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 243 256 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CDW54_RS11165 31ee1622135bcce9406216937f9f444a 304 Pfam PF00294 pfkB family carbohydrate kinase 11 280 4.9E-52 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CDW54_RS11165 31ee1622135bcce9406216937f9f444a 304 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 2 301 1.3E-106 T 28-03-2018 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 CDW54_RS11165 31ee1622135bcce9406216937f9f444a 304 Gene3D G3DSA:2.20.150.10 9 42 8.7E-15 T 28-03-2018 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain CDW54_RS11165 31ee1622135bcce9406216937f9f444a 304 Gene3D G3DSA:3.40.1190.20 43 304 1.0E-39 T 28-03-2018 IPR029056 Ribokinase-like CDW54_RS04425 aa35b0a20f746479496bba4d1c8de143 483 Gene3D G3DSA:1.10.10.60 427 481 2.8E-16 T 28-03-2018 CDW54_RS04425 aa35b0a20f746479496bba4d1c8de143 483 Pfam PF12833 Helix-turn-helix domain 402 478 4.8E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CDW54_RS04425 aa35b0a20f746479496bba4d1c8de143 483 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 446 461 1.7E-7 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CDW54_RS04425 aa35b0a20f746479496bba4d1c8de143 483 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 461 477 1.7E-7 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CDW54_RS04425 aa35b0a20f746479496bba4d1c8de143 483 SUPERFAMILY SSF52172 4 144 8.82E-31 T 28-03-2018 IPR011006 CheY-like superfamily CDW54_RS04425 aa35b0a20f746479496bba4d1c8de143 483 SUPERFAMILY SSF46689 430 479 3.36E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDW54_RS04425 aa35b0a20f746479496bba4d1c8de143 483 Pfam PF00072 Response regulator receiver domain 6 118 2.5E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDW54_RS04425 aa35b0a20f746479496bba4d1c8de143 483 Gene3D G3DSA:3.40.50.2300 2 301 5.7E-31 T 28-03-2018 CDW54_RS04425 aa35b0a20f746479496bba4d1c8de143 483 SMART SM00342 394 477 1.7E-31 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CDW54_RS04425 aa35b0a20f746479496bba4d1c8de143 483 SMART SM00448 4 118 1.0E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDW54_RS04425 aa35b0a20f746479496bba4d1c8de143 483 SUPERFAMILY SSF46689 379 427 4.3E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDW54_RS04425 aa35b0a20f746479496bba4d1c8de143 483 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 431 473 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CDW54_RS04425 aa35b0a20f746479496bba4d1c8de143 483 Gene3D G3DSA:1.10.10.60 368 426 1.0E-15 T 28-03-2018 CDW54_RS08540 78baa930cf9e2ebdc18b4db33e94cbce 1150 SUPERFAMILY SSF53300 304 428 8.21E-22 T 28-03-2018 IPR002035 von Willebrand factor, type A CDW54_RS08540 78baa930cf9e2ebdc18b4db33e94cbce 1150 SUPERFAMILY SSF53300 483 532 8.21E-22 T 28-03-2018 IPR002035 von Willebrand factor, type A CDW54_RS08540 78baa930cf9e2ebdc18b4db33e94cbce 1150 SUPERFAMILY SSF49478 668 786 9.61E-11 T 28-03-2018 CDW54_RS08540 78baa930cf9e2ebdc18b4db33e94cbce 1150 Gene3D G3DSA:2.60.40.810 991 1114 1.2E-16 T 28-03-2018 CDW54_RS08540 78baa930cf9e2ebdc18b4db33e94cbce 1150 Gene3D G3DSA:2.60.40.810 883 990 1.3E-16 T 28-03-2018 CDW54_RS08540 78baa930cf9e2ebdc18b4db33e94cbce 1150 Gene3D G3DSA:2.60.40.1140 667 790 5.1E-10 T 28-03-2018 CDW54_RS08540 78baa930cf9e2ebdc18b4db33e94cbce 1150 Gene3D G3DSA:3.40.50.410 305 569 5.6E-28 T 28-03-2018 IPR002035 von Willebrand factor, type A CDW54_RS08540 78baa930cf9e2ebdc18b4db33e94cbce 1150 Gene3D G3DSA:2.60.40.1140 791 882 2.3E-9 T 28-03-2018 CDW54_RS08540 78baa930cf9e2ebdc18b4db33e94cbce 1150 Pfam PF00092 von Willebrand factor type A domain 313 531 3.3E-10 T 28-03-2018 IPR002035 von Willebrand factor, type A CDW54_RS08540 78baa930cf9e2ebdc18b4db33e94cbce 1150 SUPERFAMILY SSF49478 909 975 2.31E-6 T 28-03-2018 CDW54_RS08540 78baa930cf9e2ebdc18b4db33e94cbce 1150 SMART SM00327 311 551 8.1E-14 T 28-03-2018 IPR002035 von Willebrand factor, type A CDW54_RS08070 a2145470f5a9010028d65deb8e8c7566 133 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 5 131 1.1E-46 T 28-03-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 CDW54_RS08070 a2145470f5a9010028d65deb8e8c7566 133 Gene3D G3DSA:3.30.300.20 1 133 6.6E-34 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CDW54_RS08070 a2145470f5a9010028d65deb8e8c7566 133 SUPERFAMILY SSF82784 1 132 6.54E-35 T 28-03-2018 IPR003718 OsmC/Ohr family CDW54_RS08070 a2145470f5a9010028d65deb8e8c7566 133 Pfam PF02566 OsmC-like protein 37 130 7.9E-18 T 28-03-2018 IPR003718 OsmC/Ohr family CDW54_RS09440 2bb4ee87f3ee06bf3c57f57a23a3350a 156 SUPERFAMILY SSF81333 13 77 6.8E-10 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CDW54_RS09440 2bb4ee87f3ee06bf3c57f57a23a3350a 156 SUPERFAMILY SSF81333 84 153 6.02E-14 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CDW54_RS09440 2bb4ee87f3ee06bf3c57f57a23a3350a 156 Pfam PF00137 ATP synthase subunit C 93 152 9.8E-17 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CDW54_RS09440 2bb4ee87f3ee06bf3c57f57a23a3350a 156 Pfam PF00137 ATP synthase subunit C 17 76 1.2E-14 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CDW54_RS09440 2bb4ee87f3ee06bf3c57f57a23a3350a 156 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 104 130 6.7E-12 T 28-03-2018 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CDW54_RS09440 2bb4ee87f3ee06bf3c57f57a23a3350a 156 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 131 154 6.7E-12 T 28-03-2018 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CDW54_RS09440 2bb4ee87f3ee06bf3c57f57a23a3350a 156 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 56 80 6.7E-12 T 28-03-2018 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CDW54_RS09440 2bb4ee87f3ee06bf3c57f57a23a3350a 156 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 30 54 6.7E-12 T 28-03-2018 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CDW54_RS09440 2bb4ee87f3ee06bf3c57f57a23a3350a 156 Gene3D G3DSA:1.20.20.10 84 155 7.4E-16 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CDW54_RS09440 2bb4ee87f3ee06bf3c57f57a23a3350a 156 Gene3D G3DSA:1.20.20.10 11 79 2.3E-13 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CDW54_RS02840 012939e75a7e1107592503fa7616a933 764 Gene3D G3DSA:2.60.420.10 681 752 1.6E-20 T 28-03-2018 CDW54_RS02840 012939e75a7e1107592503fa7616a933 764 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 17 269 2.5E-59 T 28-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 CDW54_RS02840 012939e75a7e1107592503fa7616a933 764 SUPERFAMILY SSF74650 5 270 7.53E-88 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CDW54_RS02840 012939e75a7e1107592503fa7616a933 764 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 324 695 1.2E-154 T 28-03-2018 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 CDW54_RS02840 012939e75a7e1107592503fa7616a933 764 Gene3D G3DSA:1.50.10.10 318 680 1.7E-119 T 28-03-2018 CDW54_RS02840 012939e75a7e1107592503fa7616a933 764 PIRSF PIRSF036289 1 759 1.1E-279 T 28-03-2018 IPR017045 Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase CDW54_RS02840 012939e75a7e1107592503fa7616a933 764 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 699 749 1.6E-16 T 28-03-2018 IPR005194 Glycoside hydrolase family 65, C-terminal CDW54_RS02840 012939e75a7e1107592503fa7616a933 764 Gene3D G3DSA:2.70.98.40 4 272 3.0E-71 T 28-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 CDW54_RS02840 012939e75a7e1107592503fa7616a933 764 SUPERFAMILY SSF48208 276 747 1.56E-139 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CDW54_RS01400 3647677019b7f5d867e600043037d5f2 300 Gene3D G3DSA:3.40.190.10 178 262 4.3E-18 T 28-03-2018 CDW54_RS01400 3647677019b7f5d867e600043037d5f2 300 Gene3D G3DSA:1.10.10.10 1 90 3.9E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS01400 3647677019b7f5d867e600043037d5f2 300 Pfam PF03466 LysR substrate binding domain 88 290 3.4E-32 T 28-03-2018 IPR005119 LysR, substrate-binding CDW54_RS01400 3647677019b7f5d867e600043037d5f2 300 Gene3D G3DSA:3.40.190.10 91 177 5.3E-16 T 28-03-2018 CDW54_RS01400 3647677019b7f5d867e600043037d5f2 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 4.3E-11 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDW54_RS01400 3647677019b7f5d867e600043037d5f2 300 SUPERFAMILY SSF53850 90 293 2.39E-30 T 28-03-2018 CDW54_RS01400 3647677019b7f5d867e600043037d5f2 300 SUPERFAMILY SSF46785 1 88 6.95E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS02350 bfa3496b135825caf59101f4bbea5f58 198 ProSitePatterns PS01300 RecR protein signature. 57 78 - T 28-03-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 CDW54_RS02350 bfa3496b135825caf59101f4bbea5f58 198 Pfam PF13662 Toprim domain 80 171 3.8E-25 T 28-03-2018 IPR006171 TOPRIM domain CDW54_RS02350 bfa3496b135825caf59101f4bbea5f58 198 Gene3D G3DSA:3.40.1360.10 77 170 8.6E-40 T 28-03-2018 CDW54_RS02350 bfa3496b135825caf59101f4bbea5f58 198 TIGRFAM TIGR00615 recR: recombination protein RecR 1 196 4.5E-84 T 28-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 CDW54_RS02350 bfa3496b135825caf59101f4bbea5f58 198 SMART SM00493 80 165 6.7E-17 T 28-03-2018 IPR006171 TOPRIM domain CDW54_RS02350 bfa3496b135825caf59101f4bbea5f58 198 SUPERFAMILY SSF111304 1 198 1.57E-76 T 28-03-2018 IPR023627 Recombination protein RecR CDW54_RS02350 bfa3496b135825caf59101f4bbea5f58 198 Hamap MF_00017 Recombination protein RecR [recR]. 1 198 108.271 T 28-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 CDW54_RS02350 bfa3496b135825caf59101f4bbea5f58 198 Pfam PF02132 RecR protein 40 78 2.4E-17 T 28-03-2018 IPR023628 Recombination protein RecR, C4-type zinc finger CDW54_RS02320 f66f680bfaee64fb359eb9eb4d7d7039 290 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 93 104 - T 28-03-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CDW54_RS02320 f66f680bfaee64fb359eb9eb4d7d7039 290 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 15 233 36.96 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CDW54_RS02320 f66f680bfaee64fb359eb9eb4d7d7039 290 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 16 288 2.1E-82 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CDW54_RS02320 f66f680bfaee64fb359eb9eb4d7d7039 290 Gene3D G3DSA:3.30.950.10 124 236 9.9E-41 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CDW54_RS02320 f66f680bfaee64fb359eb9eb4d7d7039 290 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 16 214 2.5E-26 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CDW54_RS02320 f66f680bfaee64fb359eb9eb4d7d7039 290 SUPERFAMILY SSF53790 14 231 8.77E-82 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CDW54_RS02320 f66f680bfaee64fb359eb9eb4d7d7039 290 Gene3D G3DSA:3.40.1010.10 13 123 1.0E-40 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CDW54_RS02320 f66f680bfaee64fb359eb9eb4d7d7039 290 PIRSF PIRSF005917 3 290 2.4E-98 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CDW54_RS05865 fde6a7b519fd05c735a86e44db1e47c1 272 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 77 118 - T 28-03-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 CDW54_RS05865 fde6a7b519fd05c735a86e44db1e47c1 272 Gene3D G3DSA:3.40.50.1580 1 272 1.9E-70 T 28-03-2018 CDW54_RS05865 fde6a7b519fd05c735a86e44db1e47c1 272 Pfam PF01048 Phosphorylase superfamily 25 269 7.9E-57 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CDW54_RS05865 fde6a7b519fd05c735a86e44db1e47c1 272 PIRSF PIRSF000477 1 272 9.3E-109 T 28-03-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 CDW54_RS05865 fde6a7b519fd05c735a86e44db1e47c1 272 TIGRFAM TIGR01700 PNPH: purine nucleoside phosphorylase I, inosine and guanosine-specific 25 268 1.0E-108 T 28-03-2018 IPR011270 Purine nucleoside phosphorylase I, inosine/guanosine-specific GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 CDW54_RS05865 fde6a7b519fd05c735a86e44db1e47c1 272 SUPERFAMILY SSF53167 4 271 4.97E-94 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CDW54_RS05865 fde6a7b519fd05c735a86e44db1e47c1 272 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 25 268 4.8E-109 T 28-03-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 CDW54_RS06545 eb0056fc8149800221cb306f6ca99179 162 SUPERFAMILY SSF55729 5 161 3.96E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDW54_RS06545 eb0056fc8149800221cb306f6ca99179 162 Pfam PF13673 Acetyltransferase (GNAT) domain 32 155 1.1E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CDW54_RS06545 eb0056fc8149800221cb306f6ca99179 162 Gene3D G3DSA:3.40.630.30 2 146 1.0E-19 T 28-03-2018 CDW54_RS06150 dbb0c1d32589acc8167ed4d66404a724 678 SUPERFAMILY SSF52540 366 625 6.39E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS06150 dbb0c1d32589acc8167ed4d66404a724 678 Pfam PF17191 RecG wedge domain 8 159 2.8E-14 T 28-03-2018 IPR033454 RecG, wedge domain CDW54_RS06150 dbb0c1d32589acc8167ed4d66404a724 678 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 25 645 7.3E-243 T 28-03-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 CDW54_RS06150 dbb0c1d32589acc8167ed4d66404a724 678 Gene3D G3DSA:2.40.50.140 54 128 6.1E-7 T 28-03-2018 CDW54_RS06150 dbb0c1d32589acc8167ed4d66404a724 678 SUPERFAMILY SSF50249 3 165 8.22E-28 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDW54_RS06150 dbb0c1d32589acc8167ed4d66404a724 678 Gene3D G3DSA:3.40.50.300 438 610 1.5E-33 T 28-03-2018 CDW54_RS06150 dbb0c1d32589acc8167ed4d66404a724 678 Gene3D G3DSA:3.40.50.300 238 437 2.7E-38 T 28-03-2018 CDW54_RS06150 dbb0c1d32589acc8167ed4d66404a724 678 Gene3D G3DSA:1.10.150.20 4 53 0.0012 T 28-03-2018 CDW54_RS06150 dbb0c1d32589acc8167ed4d66404a724 678 SMART SM00487 250 440 1.5E-33 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CDW54_RS06150 dbb0c1d32589acc8167ed4d66404a724 678 SUPERFAMILY SSF52540 170 433 9.02E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS06150 dbb0c1d32589acc8167ed4d66404a724 678 Pfam PF00270 DEAD/DEAH box helicase 257 412 1.4E-18 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CDW54_RS06150 dbb0c1d32589acc8167ed4d66404a724 678 SMART SM00490 485 570 6.3E-23 T 28-03-2018 IPR001650 Helicase, C-terminal CDW54_RS06150 dbb0c1d32589acc8167ed4d66404a724 678 SMART SM00490 320 388 0.89 T 28-03-2018 IPR001650 Helicase, C-terminal CDW54_RS06150 dbb0c1d32589acc8167ed4d66404a724 678 Pfam PF00271 Helicase conserved C-terminal domain 458 569 2.1E-19 T 28-03-2018 IPR001650 Helicase, C-terminal CDW54_RS04410 d4b369009494ebd09148edbe6184e2b8 348 SUPERFAMILY SSF46785 2 81 5.45E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS04410 d4b369009494ebd09148edbe6184e2b8 348 Gene3D G3DSA:3.40.50.2300 189 348 2.1E-44 T 28-03-2018 CDW54_RS04410 d4b369009494ebd09148edbe6184e2b8 348 Pfam PF13377 Periplasmic binding protein-like domain 191 345 2.7E-34 T 28-03-2018 CDW54_RS04410 d4b369009494ebd09148edbe6184e2b8 348 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 58 3.5E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDW54_RS04410 d4b369009494ebd09148edbe6184e2b8 348 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 28 42 3.5E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDW54_RS04410 d4b369009494ebd09148edbe6184e2b8 348 SUPERFAMILY SSF53822 84 346 5.01E-56 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CDW54_RS04410 d4b369009494ebd09148edbe6184e2b8 348 SMART SM00345 9 68 7.8E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDW54_RS04410 d4b369009494ebd09148edbe6184e2b8 348 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 68 1.3E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDW54_RS04410 d4b369009494ebd09148edbe6184e2b8 348 Gene3D G3DSA:1.10.10.10 1 70 1.4E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS04410 d4b369009494ebd09148edbe6184e2b8 348 Gene3D G3DSA:3.40.50.2300 76 188 1.4E-13 T 28-03-2018 CDW54_RS10815 108b629f1e267dff616ed9fda8a8d750 159 Pfam PF02863 Arginine repressor, C-terminal domain 86 150 1.7E-19 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CDW54_RS10815 108b629f1e267dff616ed9fda8a8d750 159 Gene3D G3DSA:1.10.10.10 3 66 1.6E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS10815 108b629f1e267dff616ed9fda8a8d750 159 PRINTS PR01467 Bacterial arginine repressor signature 37 52 2.8E-12 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CDW54_RS10815 108b629f1e267dff616ed9fda8a8d750 159 PRINTS PR01467 Bacterial arginine repressor signature 123 138 2.8E-12 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CDW54_RS10815 108b629f1e267dff616ed9fda8a8d750 159 PRINTS PR01467 Bacterial arginine repressor signature 21 34 2.8E-12 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CDW54_RS10815 108b629f1e267dff616ed9fda8a8d750 159 PRINTS PR01467 Bacterial arginine repressor signature 93 106 2.8E-12 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CDW54_RS10815 108b629f1e267dff616ed9fda8a8d750 159 Hamap MF_00173 Arginine repressor [argR]. 1 157 47.539 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CDW54_RS10815 108b629f1e267dff616ed9fda8a8d750 159 Gene3D G3DSA:3.30.1360.40 79 151 1.1E-21 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CDW54_RS10815 108b629f1e267dff616ed9fda8a8d750 159 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 92 135 1.0E-5 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CDW54_RS10815 108b629f1e267dff616ed9fda8a8d750 159 SUPERFAMILY SSF55252 85 151 4.19E-18 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CDW54_RS10815 108b629f1e267dff616ed9fda8a8d750 159 SUPERFAMILY SSF46785 1 70 1.31E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS10815 108b629f1e267dff616ed9fda8a8d750 159 Pfam PF01316 Arginine repressor, DNA binding domain 1 68 1.7E-18 T 28-03-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 CDW54_RS00025 48863f1a905b8e4c28696252f21cb1da 336 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 20 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDW54_RS00025 48863f1a905b8e4c28696252f21cb1da 336 Pfam PF00579 tRNA synthetases class I (W and Y) 4 287 1.0E-57 T 28-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDW54_RS00025 48863f1a905b8e4c28696252f21cb1da 336 Gene3D G3DSA:1.10.240.10 206 328 3.3E-32 T 28-03-2018 CDW54_RS00025 48863f1a905b8e4c28696252f21cb1da 336 SUPERFAMILY SSF52374 4 332 4.23E-83 T 28-03-2018 CDW54_RS00025 48863f1a905b8e4c28696252f21cb1da 336 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 3 332 5.8E-79 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CDW54_RS00025 48863f1a905b8e4c28696252f21cb1da 336 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 68 87 6.5E-25 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CDW54_RS00025 48863f1a905b8e4c28696252f21cb1da 336 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 146 167 6.5E-25 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CDW54_RS00025 48863f1a905b8e4c28696252f21cb1da 336 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 15 31 6.5E-25 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CDW54_RS00025 48863f1a905b8e4c28696252f21cb1da 336 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 199 209 6.5E-25 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CDW54_RS00025 48863f1a905b8e4c28696252f21cb1da 336 Gene3D G3DSA:3.40.50.620 1 205 1.3E-57 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDW54_RS09370 dbd8c818fdb8ed4a3ce7869597c49ddd 305 Hamap MF_00053 Ribonuclease HIII [rnhC]. 1 303 35.187 T 28-03-2018 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 CDW54_RS09370 dbd8c818fdb8ed4a3ce7869597c49ddd 305 SUPERFAMILY SSF53098 91 304 1.47E-51 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS09370 dbd8c818fdb8ed4a3ce7869597c49ddd 305 Gene3D G3DSA:3.30.420.10 66 305 3.5E-42 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS09370 dbd8c818fdb8ed4a3ce7869597c49ddd 305 Pfam PF01351 Ribonuclease HII 92 296 1.2E-52 T 28-03-2018 IPR024567 Ribonuclease HII/HIII domain CDW54_RS09370 dbd8c818fdb8ed4a3ce7869597c49ddd 305 PIRSF PIRSF037748 1 304 4.0E-120 T 28-03-2018 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 CDW54_RS09370 dbd8c818fdb8ed4a3ce7869597c49ddd 305 TIGRFAM TIGR00716 rnhC: ribonuclease HIII 7 295 6.6E-80 T 28-03-2018 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 CDW54_RS09370 dbd8c818fdb8ed4a3ce7869597c49ddd 305 Pfam PF11858 Domain of unknown function (DUF3378) 3 74 1.1E-29 T 28-03-2018 IPR024568 Ribonuclease HIII, N-terminal CDW54_RS09540 9293280a33bf245a7999fcd5906fa8c0 299 Pfam PF11738 Protein of unknown function (DUF3298) 200 285 8.7E-17 T 28-03-2018 IPR021729 Domain of unknown function DUF3298 CDW54_RS09540 9293280a33bf245a7999fcd5906fa8c0 299 Gene3D G3DSA:3.90.640.20 196 299 4.1E-22 T 28-03-2018 IPR021729 Domain of unknown function DUF3298 CDW54_RS12635 8714036241ff84e3d2f314dd235b5767 313 Pfam PF00753 Metallo-beta-lactamase superfamily 30 84 2.2E-8 T 28-03-2018 IPR001279 Metallo-beta-lactamase CDW54_RS12635 8714036241ff84e3d2f314dd235b5767 313 Gene3D G3DSA:3.60.15.10 1 313 2.6E-59 T 28-03-2018 IPR001279 Metallo-beta-lactamase CDW54_RS12635 8714036241ff84e3d2f314dd235b5767 313 SUPERFAMILY SSF56281 1 305 8.67E-86 T 28-03-2018 IPR001279 Metallo-beta-lactamase CDW54_RS12635 8714036241ff84e3d2f314dd235b5767 313 Hamap MF_01818 Ribonuclease BN [rbn]. 1 305 41.789 T 28-03-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 CDW54_RS12635 8714036241ff84e3d2f314dd235b5767 313 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 2 305 1.2E-120 T 28-03-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 CDW54_RS12635 8714036241ff84e3d2f314dd235b5767 313 Pfam PF12706 Beta-lactamase superfamily domain 202 271 9.6E-8 T 28-03-2018 IPR001279 Metallo-beta-lactamase CDW54_RS03810 91500e31a96a25f733778ed71c60f858 510 Gene3D G3DSA:3.40.50.300 256 510 4.6E-37 T 28-03-2018 CDW54_RS03810 91500e31a96a25f733778ed71c60f858 510 ProSitePatterns PS00211 ABC transporters family signature. 438 452 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS03810 91500e31a96a25f733778ed71c60f858 510 Pfam PF12848 ABC transporter 228 309 3.3E-21 T 28-03-2018 IPR032781 ABC-transporter extension domain CDW54_RS03810 91500e31a96a25f733778ed71c60f858 510 SUPERFAMILY SSF52540 3 94 8.89E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS03810 91500e31a96a25f733778ed71c60f858 510 SUPERFAMILY SSF52540 129 257 8.89E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS03810 91500e31a96a25f733778ed71c60f858 510 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS03810 91500e31a96a25f733778ed71c60f858 510 SMART SM00382 345 509 3.9E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS03810 91500e31a96a25f733778ed71c60f858 510 SMART SM00382 28 235 6.4E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS03810 91500e31a96a25f733778ed71c60f858 510 Gene3D G3DSA:3.40.50.300 1 255 1.6E-54 T 28-03-2018 CDW54_RS03810 91500e31a96a25f733778ed71c60f858 510 SUPERFAMILY SSF52540 308 508 3.4E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS03810 91500e31a96a25f733778ed71c60f858 510 Pfam PF00005 ABC transporter 337 466 1.5E-20 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS03810 91500e31a96a25f733778ed71c60f858 510 Pfam PF00005 ABC transporter 20 188 1.3E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS06680 20008b6fc843e9e9aabc513c649eee16 381 SUPERFAMILY SSF51713 7 371 2.22E-157 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CDW54_RS06680 20008b6fc843e9e9aabc513c649eee16 381 Gene3D G3DSA:3.20.20.105 1 376 1.1E-156 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CDW54_RS06680 20008b6fc843e9e9aabc513c649eee16 381 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 8 375 2.9E-177 T 28-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CDW54_RS06680 20008b6fc843e9e9aabc513c649eee16 381 Pfam PF01702 Queuine tRNA-ribosyltransferase 134 367 9.8E-90 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CDW54_RS06680 20008b6fc843e9e9aabc513c649eee16 381 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 8 375 4.0E-169 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CDW54_RS06680 20008b6fc843e9e9aabc513c649eee16 381 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 6 370 56.137 T 28-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CDW54_RS10015 f90f273cede64b7ffe408af1a5afac89 270 Pfam PF11967 Recombination protein O N terminal 1 81 3.0E-19 T 28-03-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal CDW54_RS10015 f90f273cede64b7ffe408af1a5afac89 270 Hamap MF_00201 DNA repair protein RecO [recO]. 3 246 26.703 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CDW54_RS10015 f90f273cede64b7ffe408af1a5afac89 270 SUPERFAMILY SSF57863 83 235 1.31E-44 T 28-03-2018 CDW54_RS10015 f90f273cede64b7ffe408af1a5afac89 270 SUPERFAMILY SSF50249 2 81 2.74E-9 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDW54_RS10015 f90f273cede64b7ffe408af1a5afac89 270 Gene3D G3DSA:2.40.50.140 2 84 1.4E-16 T 28-03-2018 CDW54_RS10015 f90f273cede64b7ffe408af1a5afac89 270 Pfam PF02565 Recombination protein O C terminal 86 240 1.8E-42 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CDW54_RS10015 f90f273cede64b7ffe408af1a5afac89 270 TIGRFAM TIGR00613 reco: DNA repair protein RecO 7 246 1.8E-66 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CDW54_RS05435 a27870171097051f40a3fd3a319bdf0e 448 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 131 149 1.7E-26 T 28-03-2018 CDW54_RS05435 a27870171097051f40a3fd3a319bdf0e 448 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 168 186 1.7E-26 T 28-03-2018 CDW54_RS05435 a27870171097051f40a3fd3a319bdf0e 448 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 281 303 1.7E-26 T 28-03-2018 CDW54_RS05435 a27870171097051f40a3fd3a319bdf0e 448 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 252 268 1.7E-26 T 28-03-2018 CDW54_RS05435 a27870171097051f40a3fd3a319bdf0e 448 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.7E-26 T 28-03-2018 CDW54_RS05435 a27870171097051f40a3fd3a319bdf0e 448 Gene3D G3DSA:3.30.390.30 322 448 3.1E-38 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CDW54_RS05435 a27870171097051f40a3fd3a319bdf0e 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 134 143 1.8E-69 T 28-03-2018 CDW54_RS05435 a27870171097051f40a3fd3a319bdf0e 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 1.8E-69 T 28-03-2018 CDW54_RS05435 a27870171097051f40a3fd3a319bdf0e 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 422 442 1.8E-69 T 28-03-2018 CDW54_RS05435 a27870171097051f40a3fd3a319bdf0e 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 400 415 1.8E-69 T 28-03-2018 CDW54_RS05435 a27870171097051f40a3fd3a319bdf0e 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 168 193 1.8E-69 T 28-03-2018 CDW54_RS05435 a27870171097051f40a3fd3a319bdf0e 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 333 354 1.8E-69 T 28-03-2018 CDW54_RS05435 a27870171097051f40a3fd3a319bdf0e 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 37 52 1.8E-69 T 28-03-2018 CDW54_RS05435 a27870171097051f40a3fd3a319bdf0e 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 253 267 1.8E-69 T 28-03-2018 CDW54_RS05435 a27870171097051f40a3fd3a319bdf0e 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 296 303 1.8E-69 T 28-03-2018 CDW54_RS05435 a27870171097051f40a3fd3a319bdf0e 448 SUPERFAMILY SSF55424 334 448 1.72E-36 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CDW54_RS05435 a27870171097051f40a3fd3a319bdf0e 448 Gene3D G3DSA:3.40.50.720 173 321 1.5E-33 T 28-03-2018 CDW54_RS05435 a27870171097051f40a3fd3a319bdf0e 448 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 316 1.0E-65 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS05435 a27870171097051f40a3fd3a319bdf0e 448 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 38 48 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CDW54_RS05435 a27870171097051f40a3fd3a319bdf0e 448 SUPERFAMILY SSF51905 2 358 2.45E-58 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS05435 a27870171097051f40a3fd3a319bdf0e 448 Gene3D G3DSA:3.50.50.60 1 172 2.9E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS05435 a27870171097051f40a3fd3a319bdf0e 448 PIRSF PIRSF000350 1 444 1.1E-86 T 28-03-2018 CDW54_RS05435 a27870171097051f40a3fd3a319bdf0e 448 TIGRFAM TIGR01421 gluta_reduc_1: glutathione-disulfide reductase 3 448 3.0E-214 T 28-03-2018 IPR006322 Glutathione reductase, eukaryote/bacterial GO:0004362|GO:0006749|GO:0050660|GO:0050661|GO:0055114 KEGG: 00480+1.8.1.7|MetaCyc: PWY-4081|Reactome: R-HSA-2408550|Reactome: R-HSA-3299685|Reactome: R-HSA-499943|Reactome: R-HSA-5628897 CDW54_RS05435 a27870171097051f40a3fd3a319bdf0e 448 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 337 447 2.7E-35 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CDW54_RS04835 e2c73452f485591470c4f1a794321bb2 466 Pfam PF12229 Putative peptidoglycan binding domain 210 323 9.3E-16 T 28-03-2018 IPR022029 Putative peptidoglycan binding domain CDW54_RS04835 e2c73452f485591470c4f1a794321bb2 466 Pfam PF12229 Putative peptidoglycan binding domain 110 199 1.6E-9 T 28-03-2018 IPR022029 Putative peptidoglycan binding domain CDW54_RS04835 e2c73452f485591470c4f1a794321bb2 466 SUPERFAMILY SSF141523 340 465 8.11E-40 T 28-03-2018 CDW54_RS04835 e2c73452f485591470c4f1a794321bb2 466 Pfam PF03734 L,D-transpeptidase catalytic domain 343 465 6.6E-23 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CDW54_RS04835 e2c73452f485591470c4f1a794321bb2 466 Gene3D G3DSA:2.40.440.10 342 466 5.9E-33 T 28-03-2018 CDW54_RS04835 e2c73452f485591470c4f1a794321bb2 466 SUPERFAMILY SSF143985 218 332 1.57E-33 T 28-03-2018 CDW54_RS10775 f21ca75d26f437871e76aa9e763ac8a1 233 Pfam PF00027 Cyclic nucleotide-binding domain 37 123 9.1E-14 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CDW54_RS10775 f21ca75d26f437871e76aa9e763ac8a1 233 Gene3D G3DSA:1.10.10.10 152 230 3.9E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS10775 f21ca75d26f437871e76aa9e763ac8a1 233 Gene3D G3DSA:2.60.120.10 8 147 8.0E-24 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CDW54_RS10775 f21ca75d26f437871e76aa9e763ac8a1 233 SUPERFAMILY SSF51206 23 147 3.93E-31 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like CDW54_RS10775 f21ca75d26f437871e76aa9e763ac8a1 233 SUPERFAMILY SSF46785 153 223 4.42E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS07375 a2b98cec4f9e435dacbd3f7279ca99d0 431 Gene3D G3DSA:3.50.50.60 1 98 1.0E-12 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS07375 a2b98cec4f9e435dacbd3f7279ca99d0 431 Gene3D G3DSA:3.30.390.30 321 430 3.1E-8 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CDW54_RS07375 a2b98cec4f9e435dacbd3f7279ca99d0 431 Gene3D G3DSA:3.50.50.60 231 313 4.1E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS07375 a2b98cec4f9e435dacbd3f7279ca99d0 431 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 2 24 1.8E-12 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDW54_RS07375 a2b98cec4f9e435dacbd3f7279ca99d0 431 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 99 107 1.8E-12 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDW54_RS07375 a2b98cec4f9e435dacbd3f7279ca99d0 431 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 138 162 1.8E-12 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDW54_RS07375 a2b98cec4f9e435dacbd3f7279ca99d0 431 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 261 279 1.8E-12 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDW54_RS07375 a2b98cec4f9e435dacbd3f7279ca99d0 431 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 98 116 4.5E-20 T 28-03-2018 CDW54_RS07375 a2b98cec4f9e435dacbd3f7279ca99d0 431 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 142 160 4.5E-20 T 28-03-2018 CDW54_RS07375 a2b98cec4f9e435dacbd3f7279ca99d0 431 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 251 273 4.5E-20 T 28-03-2018 CDW54_RS07375 a2b98cec4f9e435dacbd3f7279ca99d0 431 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 4.5E-20 T 28-03-2018 CDW54_RS07375 a2b98cec4f9e435dacbd3f7279ca99d0 431 Gene3D G3DSA:3.50.50.60 99 230 2.3E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS07375 a2b98cec4f9e435dacbd3f7279ca99d0 431 SUPERFAMILY SSF51905 1 305 1.51E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS07375 a2b98cec4f9e435dacbd3f7279ca99d0 431 SUPERFAMILY SSF55424 317 428 1.27E-15 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CDW54_RS07375 a2b98cec4f9e435dacbd3f7279ca99d0 431 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 296 3.4E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS10830 e7b2bf0bebd049bd9d02380dea41dbf6 240 SUPERFAMILY SSF53633 4 238 9.03E-75 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CDW54_RS10830 e7b2bf0bebd049bd9d02380dea41dbf6 240 PIRSF PIRSF005650 1 240 5.8E-98 T 28-03-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 CDW54_RS10830 e7b2bf0bebd049bd9d02380dea41dbf6 240 Hamap MF_01220_B Uridylate kinase [pyrH]. 4 238 45.052 T 28-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CDW54_RS10830 e7b2bf0bebd049bd9d02380dea41dbf6 240 Pfam PF00696 Amino acid kinase family 7 217 7.2E-31 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CDW54_RS10830 e7b2bf0bebd049bd9d02380dea41dbf6 240 Gene3D G3DSA:3.40.1160.10 2 239 2.2E-45 T 28-03-2018 CDW54_RS10830 e7b2bf0bebd049bd9d02380dea41dbf6 240 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 6 237 8.3E-100 T 28-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CDW54_RS10540 365ae459d157bf2a983d5e1ed3c2e386 482 Pfam PF00672 HAMP domain 198 243 3.6E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDW54_RS10540 365ae459d157bf2a983d5e1ed3c2e386 482 Gene3D G3DSA:1.10.287.130 245 315 1.3E-15 T 28-03-2018 CDW54_RS10540 365ae459d157bf2a983d5e1ed3c2e386 482 SUPERFAMILY SSF55874 310 475 7.6E-39 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS10540 365ae459d157bf2a983d5e1ed3c2e386 482 SUPERFAMILY SSF158472 198 244 7.98E-10 T 28-03-2018 CDW54_RS10540 365ae459d157bf2a983d5e1ed3c2e386 482 SUPERFAMILY SSF47384 239 322 5.1E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDW54_RS10540 365ae459d157bf2a983d5e1ed3c2e386 482 SMART SM00387 366 478 6.9E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS10540 365ae459d157bf2a983d5e1ed3c2e386 482 SMART SM00304 195 247 2.1E-12 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDW54_RS10540 365ae459d157bf2a983d5e1ed3c2e386 482 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 367 476 9.3E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS10540 365ae459d157bf2a983d5e1ed3c2e386 482 PRINTS PR00344 Bacterial sensor protein C-terminal signature 462 475 9.9E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDW54_RS10540 365ae459d157bf2a983d5e1ed3c2e386 482 PRINTS PR00344 Bacterial sensor protein C-terminal signature 438 456 9.9E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDW54_RS10540 365ae459d157bf2a983d5e1ed3c2e386 482 PRINTS PR00344 Bacterial sensor protein C-terminal signature 402 416 9.9E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDW54_RS10540 365ae459d157bf2a983d5e1ed3c2e386 482 Gene3D G3DSA:3.30.450.20 26 171 1.8E-4 T 28-03-2018 CDW54_RS10540 365ae459d157bf2a983d5e1ed3c2e386 482 Gene3D G3DSA:3.30.565.10 316 476 3.1E-40 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS10540 365ae459d157bf2a983d5e1ed3c2e386 482 Pfam PF00512 His Kinase A (phospho-acceptor) domain 256 320 3.3E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDW54_RS10540 365ae459d157bf2a983d5e1ed3c2e386 482 SMART SM00388 255 321 9.0E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDW54_RS08815 6bef4e6f8d72ad44ab0082ad96d3dd64 233 Gene3D G3DSA:3.40.50.300 1 219 3.0E-37 T 28-03-2018 CDW54_RS08815 6bef4e6f8d72ad44ab0082ad96d3dd64 233 Pfam PF01712 Deoxynucleoside kinase 4 209 3.4E-55 T 28-03-2018 IPR031314 Deoxynucleoside kinase domain CDW54_RS08815 6bef4e6f8d72ad44ab0082ad96d3dd64 233 PIRSF PIRSF000705 1 216 2.4E-53 T 28-03-2018 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 CDW54_RS08815 6bef4e6f8d72ad44ab0082ad96d3dd64 233 SUPERFAMILY SSF52540 2 209 5.4E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS06200 d4a409372c1671e07dc197792e87266c 1193 SUPERFAMILY SSF52540 1 214 2.16E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS06200 d4a409372c1671e07dc197792e87266c 1193 SUPERFAMILY SSF52540 1078 1164 2.16E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS06200 d4a409372c1671e07dc197792e87266c 1193 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1179 0.0 T 28-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 CDW54_RS06200 d4a409372c1671e07dc197792e87266c 1193 Gene3D G3DSA:1.20.5.340 753 855 2.3E-6 T 28-03-2018 CDW54_RS06200 d4a409372c1671e07dc197792e87266c 1193 Gene3D G3DSA:1.20.5.340 856 948 0.031 T 28-03-2018 CDW54_RS06200 d4a409372c1671e07dc197792e87266c 1193 Gene3D G3DSA:1.20.5.340 675 752 0.16 T 28-03-2018 CDW54_RS06200 d4a409372c1671e07dc197792e87266c 1193 Gene3D G3DSA:1.10.287.620 173 339 0.012 T 28-03-2018 CDW54_RS06200 d4a409372c1671e07dc197792e87266c 1193 SUPERFAMILY SSF52540 835 909 5.63E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS06200 d4a409372c1671e07dc197792e87266c 1193 SUPERFAMILY SSF52540 977 1182 5.63E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS06200 d4a409372c1671e07dc197792e87266c 1193 Gene3D G3DSA:3.40.50.300 949 1184 2.7E-35 T 28-03-2018 CDW54_RS06200 d4a409372c1671e07dc197792e87266c 1193 SMART SM00968 518 637 8.0E-40 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CDW54_RS06200 d4a409372c1671e07dc197792e87266c 1193 SUPERFAMILY SSF57997 675 907 3.99E-6 T 28-03-2018 CDW54_RS06200 d4a409372c1671e07dc197792e87266c 1193 Pfam PF06470 SMC proteins Flexible Hinge Domain 518 637 1.8E-29 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CDW54_RS06200 d4a409372c1671e07dc197792e87266c 1193 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 1172 8.1E-59 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CDW54_RS06200 d4a409372c1671e07dc197792e87266c 1193 SUPERFAMILY SSF75553 479 687 2.62E-55 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CDW54_RS06200 d4a409372c1671e07dc197792e87266c 1193 Gene3D G3DSA:3.40.50.300 1 172 6.3E-40 T 28-03-2018 CDW54_RS06200 d4a409372c1671e07dc197792e87266c 1193 PIRSF PIRSF005719 1 1188 0.0 T 28-03-2018 IPR024704 Structural maintenance of chromosomes protein CDW54_RS06200 d4a409372c1671e07dc197792e87266c 1193 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1181 24.428 T 28-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 CDW54_RS03635 8bb377fd2b60433de0fd59260883d3b3 541 PRINTS PR00298 60kDa chaperonin signature 396 417 6.4E-73 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CDW54_RS03635 8bb377fd2b60433de0fd59260883d3b3 541 PRINTS PR00298 60kDa chaperonin signature 26 52 6.4E-73 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CDW54_RS03635 8bb377fd2b60433de0fd59260883d3b3 541 PRINTS PR00298 60kDa chaperonin signature 348 373 6.4E-73 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CDW54_RS03635 8bb377fd2b60433de0fd59260883d3b3 541 PRINTS PR00298 60kDa chaperonin signature 82 109 6.4E-73 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CDW54_RS03635 8bb377fd2b60433de0fd59260883d3b3 541 PRINTS PR00298 60kDa chaperonin signature 266 289 6.4E-73 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CDW54_RS03635 8bb377fd2b60433de0fd59260883d3b3 541 SUPERFAMILY SSF52029 182 374 1.5E-85 T 28-03-2018 IPR027409 GroEL-like apical domain CDW54_RS03635 8bb377fd2b60433de0fd59260883d3b3 541 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 522 3.8E-104 T 28-03-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 CDW54_RS03635 8bb377fd2b60433de0fd59260883d3b3 541 Hamap MF_00600 60 kDa chaperonin [groL]. 1 540 41.236 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CDW54_RS03635 8bb377fd2b60433de0fd59260883d3b3 541 SUPERFAMILY SSF54849 137 205 9.84E-25 T 28-03-2018 CDW54_RS03635 8bb377fd2b60433de0fd59260883d3b3 541 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 523 1.0E-255 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CDW54_RS03635 8bb377fd2b60433de0fd59260883d3b3 541 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 28-03-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CDW54_RS03635 8bb377fd2b60433de0fd59260883d3b3 541 Gene3D G3DSA:1.10.560.10 371 513 9.0E-27 T 28-03-2018 IPR027413 GroEL-like equatorial domain CDW54_RS03635 8bb377fd2b60433de0fd59260883d3b3 541 Gene3D G3DSA:1.10.560.10 1 185 4.8E-41 T 28-03-2018 IPR027413 GroEL-like equatorial domain CDW54_RS03635 8bb377fd2b60433de0fd59260883d3b3 541 SUPERFAMILY SSF48592 6 133 2.21E-78 T 28-03-2018 CDW54_RS03635 8bb377fd2b60433de0fd59260883d3b3 541 SUPERFAMILY SSF48592 404 518 2.21E-78 T 28-03-2018 CDW54_RS03635 8bb377fd2b60433de0fd59260883d3b3 541 Gene3D G3DSA:3.50.7.10 186 370 1.1E-99 T 28-03-2018 IPR027409 GroEL-like apical domain CDW54_RS04975 53bca4ac76fc71d706cc0ed01f6b4dbd 272 Pfam PF00156 Phosphoribosyl transferase domain 109 256 1.1E-22 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CDW54_RS04975 53bca4ac76fc71d706cc0ed01f6b4dbd 272 ProDom PD029816 REPRESSOR OPERON PUR TRANSCRIPTION PURINE TRANSCRIPTIONAL PURR REGULATION DNA-BINDING GLYCOSYLTRANSFERASE 9 73 2.0E-31 T 28-03-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 CDW54_RS04975 53bca4ac76fc71d706cc0ed01f6b4dbd 272 Gene3D G3DSA:3.40.50.2020 74 271 9.4E-29 T 28-03-2018 CDW54_RS04975 53bca4ac76fc71d706cc0ed01f6b4dbd 272 SUPERFAMILY SSF46785 2 73 7.75E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS04975 53bca4ac76fc71d706cc0ed01f6b4dbd 272 TIGRFAM TIGR01743 purR_Bsub: pur operon repressor PurR 4 269 1.0E-116 T 28-03-2018 IPR010078 Pur operon repressor GO:0003677|GO:0045892|GO:0045982 CDW54_RS04975 53bca4ac76fc71d706cc0ed01f6b4dbd 272 Pfam PF09182 Bacterial purine repressor, N-terminal 4 73 4.7E-32 T 28-03-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 CDW54_RS04975 53bca4ac76fc71d706cc0ed01f6b4dbd 272 SUPERFAMILY SSF53271 85 242 1.07E-35 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CDW54_RS04975 53bca4ac76fc71d706cc0ed01f6b4dbd 272 Gene3D G3DSA:1.10.10.10 1 73 3.4E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS10065 3a17ae5c78fd3c4d3bcc0e8a4d096744 354 SUPERFAMILY SSF53756 47 353 5.23E-51 T 28-03-2018 CDW54_RS10065 3a17ae5c78fd3c4d3bcc0e8a4d096744 354 Gene3D G3DSA:3.40.50.2000 163 335 2.8E-30 T 28-03-2018 CDW54_RS10065 3a17ae5c78fd3c4d3bcc0e8a4d096744 354 Pfam PF00534 Glycosyl transferases group 1 173 330 9.8E-25 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CDW54_RS05095 18859b535db011fe1c3f45dbf300f921 486 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 10 21 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDW54_RS05095 18859b535db011fe1c3f45dbf300f921 486 SUPERFAMILY SSF48163 299 484 3.27E-48 T 28-03-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CDW54_RS05095 18859b535db011fe1c3f45dbf300f921 486 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 3 485 34.105 T 28-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CDW54_RS05095 18859b535db011fe1c3f45dbf300f921 486 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 3 324 1.5E-123 T 28-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 CDW54_RS05095 18859b535db011fe1c3f45dbf300f921 486 Gene3D G3DSA:1.10.10.350 387 486 2.4E-27 T 28-03-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CDW54_RS05095 18859b535db011fe1c3f45dbf300f921 486 PRINTS PR00987 Glutamyl-tRNA synthetase signature 36 49 5.3E-29 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CDW54_RS05095 18859b535db011fe1c3f45dbf300f921 486 PRINTS PR00987 Glutamyl-tRNA synthetase signature 194 204 5.3E-29 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CDW54_RS05095 18859b535db011fe1c3f45dbf300f921 486 PRINTS PR00987 Glutamyl-tRNA synthetase signature 21 32 5.3E-29 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CDW54_RS05095 18859b535db011fe1c3f45dbf300f921 486 PRINTS PR00987 Glutamyl-tRNA synthetase signature 7 19 5.3E-29 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CDW54_RS05095 18859b535db011fe1c3f45dbf300f921 486 PRINTS PR00987 Glutamyl-tRNA synthetase signature 210 218 5.3E-29 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CDW54_RS05095 18859b535db011fe1c3f45dbf300f921 486 Gene3D G3DSA:3.40.50.620 4 124 1.9E-35 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDW54_RS05095 18859b535db011fe1c3f45dbf300f921 486 Gene3D G3DSA:3.40.50.620 125 246 7.9E-30 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDW54_RS05095 18859b535db011fe1c3f45dbf300f921 486 Gene3D G3DSA:1.10.1160.10 248 333 1.5E-30 T 28-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 CDW54_RS05095 18859b535db011fe1c3f45dbf300f921 486 SUPERFAMILY SSF52374 3 317 5.36E-112 T 28-03-2018 CDW54_RS05095 18859b535db011fe1c3f45dbf300f921 486 Gene3D G3DSA:1.10.8.70 335 385 5.8E-8 T 28-03-2018 IPR020752 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 1 GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 CDW54_RS05095 18859b535db011fe1c3f45dbf300f921 486 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 3 485 4.2E-184 T 28-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CDW54_RS11275 ed1bade94a3c1efdedc2f13eaf061b18 354 Gene3D G3DSA:1.20.1090.10 172 353 2.2E-53 T 28-03-2018 CDW54_RS11275 ed1bade94a3c1efdedc2f13eaf061b18 354 PIRSF PIRSF001455 1 351 6.9E-103 T 28-03-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CDW54_RS11275 ed1bade94a3c1efdedc2f13eaf061b18 354 Pfam PF01761 3-dehydroquinate synthase 67 321 4.8E-95 T 28-03-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CDW54_RS11275 ed1bade94a3c1efdedc2f13eaf061b18 354 SUPERFAMILY SSF56796 3 351 4.19E-101 T 28-03-2018 CDW54_RS11275 ed1bade94a3c1efdedc2f13eaf061b18 354 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 2 354 36.595 T 28-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CDW54_RS11275 ed1bade94a3c1efdedc2f13eaf061b18 354 Gene3D G3DSA:3.40.50.1970 3 171 6.1E-51 T 28-03-2018 CDW54_RS11275 ed1bade94a3c1efdedc2f13eaf061b18 354 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 11 345 7.1E-112 T 28-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CDW54_RS05295 45876d8aa0fe42c100dd257dcf02c735 727 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 666 716 8.6E-12 T 28-03-2018 IPR005194 Glycoside hydrolase family 65, C-terminal CDW54_RS05295 45876d8aa0fe42c100dd257dcf02c735 727 PIRSF PIRSF036289 1 725 3.2E-209 T 28-03-2018 IPR017045 Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase CDW54_RS05295 45876d8aa0fe42c100dd257dcf02c735 727 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 288 662 1.4E-127 T 28-03-2018 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 CDW54_RS05295 45876d8aa0fe42c100dd257dcf02c735 727 Gene3D G3DSA:1.50.10.10 282 647 6.5E-100 T 28-03-2018 CDW54_RS05295 45876d8aa0fe42c100dd257dcf02c735 727 Gene3D G3DSA:2.70.98.40 1 237 1.5E-49 T 28-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 CDW54_RS05295 45876d8aa0fe42c100dd257dcf02c735 727 SUPERFAMILY SSF48208 242 713 2.21E-110 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CDW54_RS05295 45876d8aa0fe42c100dd257dcf02c735 727 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 5 233 1.3E-49 T 28-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 CDW54_RS05295 45876d8aa0fe42c100dd257dcf02c735 727 Gene3D G3DSA:2.60.420.10 648 719 2.8E-14 T 28-03-2018 CDW54_RS05295 45876d8aa0fe42c100dd257dcf02c735 727 SUPERFAMILY SSF74650 2 235 5.34E-56 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CDW54_RS05015 191615efd75237045ee9ef33d92bac93 349 SUPERFAMILY SSF54752 268 326 3.01E-20 T 28-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal CDW54_RS05015 191615efd75237045ee9ef33d92bac93 349 Pfam PF00154 recA bacterial DNA recombination protein 8 268 9.9E-143 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CDW54_RS05015 191615efd75237045ee9ef33d92bac93 349 SMART SM00382 57 228 9.4E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS05015 191615efd75237045ee9ef33d92bac93 349 ProSitePatterns PS00321 recA signature. 213 221 - T 28-03-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 CDW54_RS05015 191615efd75237045ee9ef33d92bac93 349 PRINTS PR00142 RecA protein signature 93 122 1.0E-83 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CDW54_RS05015 191615efd75237045ee9ef33d92bac93 349 PRINTS PR00142 RecA protein signature 165 194 1.0E-83 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CDW54_RS05015 191615efd75237045ee9ef33d92bac93 349 PRINTS PR00142 RecA protein signature 297 314 1.0E-83 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CDW54_RS05015 191615efd75237045ee9ef33d92bac93 349 PRINTS PR00142 RecA protein signature 243 272 1.0E-83 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CDW54_RS05015 191615efd75237045ee9ef33d92bac93 349 PRINTS PR00142 RecA protein signature 210 238 1.0E-83 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CDW54_RS05015 191615efd75237045ee9ef33d92bac93 349 PRINTS PR00142 RecA protein signature 127 156 1.0E-83 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CDW54_RS05015 191615efd75237045ee9ef33d92bac93 349 Gene3D G3DSA:3.40.50.300 26 268 1.9E-44 T 28-03-2018 CDW54_RS05015 191615efd75237045ee9ef33d92bac93 349 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 4 323 6.4E-169 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CDW54_RS05015 191615efd75237045ee9ef33d92bac93 349 Gene3D G3DSA:3.30.250.10 269 325 4.0E-22 T 28-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal CDW54_RS05015 191615efd75237045ee9ef33d92bac93 349 SUPERFAMILY SSF52540 3 267 9.25E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS05015 191615efd75237045ee9ef33d92bac93 349 Hamap MF_00268 Protein RecA [recA]. 5 329 51.896 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CDW54_RS09660 ffdbc0a6ce0d3651dbde8c3d5afa84cf 468 SUPERFAMILY SSF52540 81 350 2.22E-88 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS09660 ffdbc0a6ce0d3651dbde8c3d5afa84cf 468 Gene3D G3DSA:3.40.50.300 80 353 9.8E-91 T 28-03-2018 CDW54_RS09660 ffdbc0a6ce0d3651dbde8c3d5afa84cf 468 SUPERFAMILY SSF50615 2 78 4.19E-23 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CDW54_RS09660 ffdbc0a6ce0d3651dbde8c3d5afa84cf 468 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 77 3.1E-22 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CDW54_RS09660 ffdbc0a6ce0d3651dbde8c3d5afa84cf 468 Gene3D G3DSA:1.10.1140.10 354 464 3.9E-40 T 28-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CDW54_RS09660 ffdbc0a6ce0d3651dbde8c3d5afa84cf 468 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 135 348 1.4E-67 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CDW54_RS09660 ffdbc0a6ce0d3651dbde8c3d5afa84cf 468 Gene3D G3DSA:2.40.10.170 1 79 9.7E-29 T 28-03-2018 CDW54_RS09660 ffdbc0a6ce0d3651dbde8c3d5afa84cf 468 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 339 348 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CDW54_RS09660 ffdbc0a6ce0d3651dbde8c3d5afa84cf 468 SMART SM00382 147 332 2.8E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS09660 ffdbc0a6ce0d3651dbde8c3d5afa84cf 468 SUPERFAMILY SSF47917 351 466 6.8E-50 T 28-03-2018 CDW54_RS09660 ffdbc0a6ce0d3651dbde8c3d5afa84cf 468 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 466 8.7E-252 T 28-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 CDW54_RS09660 ffdbc0a6ce0d3651dbde8c3d5afa84cf 468 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 466 57.026 T 28-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 CDW54_RS04210 57eb52e3b3e6f139ebd9540882dbcf4e 144 SUPERFAMILY SSF54197 2 138 1.7E-42 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CDW54_RS04210 57eb52e3b3e6f139ebd9540882dbcf4e 144 PRINTS PR00332 Histidine triad family signature 94 104 5.3E-17 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CDW54_RS04210 57eb52e3b3e6f139ebd9540882dbcf4e 144 PRINTS PR00332 Histidine triad family signature 26 44 5.3E-17 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CDW54_RS04210 57eb52e3b3e6f139ebd9540882dbcf4e 144 PRINTS PR00332 Histidine triad family signature 5 21 5.3E-17 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CDW54_RS04210 57eb52e3b3e6f139ebd9540882dbcf4e 144 Gene3D G3DSA:3.30.428.10 1 139 8.1E-38 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CDW54_RS04210 57eb52e3b3e6f139ebd9540882dbcf4e 144 ProSitePatterns PS00892 HIT domain signature. 87 105 - T 28-03-2018 IPR019808 Histidine triad, conserved site CDW54_RS04210 57eb52e3b3e6f139ebd9540882dbcf4e 144 Pfam PF01230 HIT domain 12 108 2.3E-25 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CDW54_RS05280 388aec840edcf9df1d52f88840d39da8 175 Gene3D G3DSA:3.30.1060.10 1 171 1.9E-68 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CDW54_RS05280 388aec840edcf9df1d52f88840d39da8 175 SUPERFAMILY SSF55068 2 164 3.4E-73 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CDW54_RS05280 388aec840edcf9df1d52f88840d39da8 175 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 2 161 37.426 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CDW54_RS05280 388aec840edcf9df1d52f88840d39da8 175 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 3 154 1.5E-62 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CDW54_RS05280 388aec840edcf9df1d52f88840d39da8 175 Pfam PF01625 Peptide methionine sulfoxide reductase 4 154 1.3E-62 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CDW54_RS01645 6935718035efb2823cb317d94d0617cd 458 SMART SM01091 352 432 4.9E-21 T 28-03-2018 IPR005170 Transporter-associated domain CDW54_RS01645 6935718035efb2823cb317d94d0617cd 458 Pfam PF01595 Domain of unknown function DUF21 15 200 1.7E-46 T 28-03-2018 IPR002550 Domain of unknown function DUF21 CDW54_RS01645 6935718035efb2823cb317d94d0617cd 458 SMART SM00116 289 337 41.0 T 28-03-2018 IPR000644 CBS domain CDW54_RS01645 6935718035efb2823cb317d94d0617cd 458 SMART SM00116 225 274 0.086 T 28-03-2018 IPR000644 CBS domain CDW54_RS01645 6935718035efb2823cb317d94d0617cd 458 Gene3D G3DSA:3.10.580.10 195 344 2.2E-35 T 28-03-2018 CDW54_RS01645 6935718035efb2823cb317d94d0617cd 458 Gene3D G3DSA:3.30.465.10 345 430 8.7E-21 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CDW54_RS01645 6935718035efb2823cb317d94d0617cd 458 SUPERFAMILY SSF56176 350 430 1.45E-19 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CDW54_RS01645 6935718035efb2823cb317d94d0617cd 458 Pfam PF00571 CBS domain 218 273 5.7E-7 T 28-03-2018 IPR000644 CBS domain CDW54_RS01645 6935718035efb2823cb317d94d0617cd 458 Pfam PF00571 CBS domain 284 337 9.8E-5 T 28-03-2018 IPR000644 CBS domain CDW54_RS01645 6935718035efb2823cb317d94d0617cd 458 Pfam PF03471 Transporter associated domain 353 429 3.8E-20 T 28-03-2018 IPR005170 Transporter-associated domain CDW54_RS01645 6935718035efb2823cb317d94d0617cd 458 SUPERFAMILY SSF54631 203 340 4.67E-32 T 28-03-2018 CDW54_RS06030 6c2f5dff3d3fdbb00aa90c81a74a6dcd 72 Gene3D G3DSA:2.40.50.140 1 72 1.1E-37 T 28-03-2018 CDW54_RS06030 6c2f5dff3d3fdbb00aa90c81a74a6dcd 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 70 3.7E-39 T 28-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CDW54_RS06030 6c2f5dff3d3fdbb00aa90c81a74a6dcd 72 SMART SM00316 4 72 2.2E-5 T 28-03-2018 IPR022967 RNA-binding domain, S1 CDW54_RS06030 6c2f5dff3d3fdbb00aa90c81a74a6dcd 72 SUPERFAMILY SSF50249 2 71 3.24E-28 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDW54_RS06030 6c2f5dff3d3fdbb00aa90c81a74a6dcd 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 2.6E-28 T 28-03-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 CDW54_RS06030 6c2f5dff3d3fdbb00aa90c81a74a6dcd 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 27.335 T 28-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CDW54_RS06365 dcce588129deae55bf9235ee6de44f16 881 SUPERFAMILY SSF55271 3 113 6.41E-43 T 28-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 CDW54_RS06365 dcce588129deae55bf9235ee6de44f16 881 SUPERFAMILY SSF52540 560 793 1.18E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS06365 dcce588129deae55bf9235ee6de44f16 881 Gene3D G3DSA:3.30.420.110 132 253 6.6E-20 T 28-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 CDW54_RS06365 dcce588129deae55bf9235ee6de44f16 881 Gene3D G3DSA:3.40.1170.10 1 131 5.1E-47 T 28-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 CDW54_RS06365 dcce588129deae55bf9235ee6de44f16 881 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 7 873 25.275 T 28-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 CDW54_RS06365 dcce588129deae55bf9235ee6de44f16 881 SMART SM00534 602 789 1.1E-118 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CDW54_RS06365 dcce588129deae55bf9235ee6de44f16 881 Pfam PF00488 MutS domain V 606 792 3.8E-83 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CDW54_RS06365 dcce588129deae55bf9235ee6de44f16 881 Pfam PF05192 MutS domain III 264 552 9.4E-38 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CDW54_RS06365 dcce588129deae55bf9235ee6de44f16 881 Gene3D G3DSA:1.10.1420.10 400 528 6.1E-34 T 28-03-2018 CDW54_RS06365 dcce588129deae55bf9235ee6de44f16 881 Pfam PF05188 MutS domain II 128 244 1.1E-10 T 28-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 CDW54_RS06365 dcce588129deae55bf9235ee6de44f16 881 Pfam PF05190 MutS family domain IV 420 511 1.7E-29 T 28-03-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 CDW54_RS06365 dcce588129deae55bf9235ee6de44f16 881 Gene3D G3DSA:1.10.1420.10 254 399 3.0E-34 T 28-03-2018 CDW54_RS06365 dcce588129deae55bf9235ee6de44f16 881 PIRSF PIRSF037677 2 173 1.8E-34 T 28-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 CDW54_RS06365 dcce588129deae55bf9235ee6de44f16 881 PIRSF PIRSF037677 165 859 2.2E-139 T 28-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 CDW54_RS06365 dcce588129deae55bf9235ee6de44f16 881 SUPERFAMILY SSF53150 117 270 8.89E-31 T 28-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 CDW54_RS06365 dcce588129deae55bf9235ee6de44f16 881 Pfam PF01624 MutS domain I 8 119 2.1E-44 T 28-03-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 CDW54_RS06365 dcce588129deae55bf9235ee6de44f16 881 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 683 699 - T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CDW54_RS06365 dcce588129deae55bf9235ee6de44f16 881 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 8 879 0.0 T 28-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 CDW54_RS06365 dcce588129deae55bf9235ee6de44f16 881 Gene3D G3DSA:3.40.50.300 560 841 1.2E-41 T 28-03-2018 CDW54_RS06365 dcce588129deae55bf9235ee6de44f16 881 SMART SM00533 275 585 1.5E-104 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CDW54_RS06365 dcce588129deae55bf9235ee6de44f16 881 SUPERFAMILY SSF48334 258 557 2.75E-86 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CDW54_RS06745 74b87774715519558ed81a757097f92d 217 Pfam PF01712 Deoxynucleoside kinase 2 207 2.4E-58 T 28-03-2018 IPR031314 Deoxynucleoside kinase domain CDW54_RS06745 74b87774715519558ed81a757097f92d 217 SUPERFAMILY SSF52540 1 207 1.1E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS06745 74b87774715519558ed81a757097f92d 217 Gene3D G3DSA:3.40.50.300 1 217 5.3E-39 T 28-03-2018 CDW54_RS06745 74b87774715519558ed81a757097f92d 217 PIRSF PIRSF000705 1 216 2.3E-53 T 28-03-2018 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 CDW54_RS02265 1d3400869ede5f25209be791fed2e15b 422 TIGRFAM TIGR04092 LTA_DltD: D-alanyl-lipoteichoic acid biosynthesis protein DltD 9 390 7.8E-144 T 28-03-2018 IPR023896 D-alanyl-lipoteichoic acid biosynthesis DltD, Firmicutes CDW54_RS02265 1d3400869ede5f25209be791fed2e15b 422 Gene3D G3DSA:3.40.50.1110 42 393 1.6E-4 T 28-03-2018 CDW54_RS02265 1d3400869ede5f25209be791fed2e15b 422 PIRSF PIRSF021438 1 393 2.3E-137 T 28-03-2018 IPR023896 D-alanyl-lipoteichoic acid biosynthesis DltD, Firmicutes CDW54_RS02265 1d3400869ede5f25209be791fed2e15b 422 Pfam PF04914 DltD protein 42 390 7.3E-127 T 28-03-2018 IPR006998 DltD CDW54_RS01435 e12fb49d6c45cc51b97ef38a7eb01ba3 269 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 263 7.5E-52 T 28-03-2018 IPR000150 Cof family GO:0016787 CDW54_RS01435 e12fb49d6c45cc51b97ef38a7eb01ba3 269 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 235 2.5E-23 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CDW54_RS01435 e12fb49d6c45cc51b97ef38a7eb01ba3 269 SUPERFAMILY SSF56784 2 267 9.37E-65 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS01435 e12fb49d6c45cc51b97ef38a7eb01ba3 269 Gene3D G3DSA:3.40.50.1000 1 269 3.3E-36 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS01435 e12fb49d6c45cc51b97ef38a7eb01ba3 269 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 263 3.2E-61 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS04030 19700f66cf10260a4783c61b7c542084 100 Gene3D G3DSA:3.40.1440.10 1 87 3.7E-9 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CDW54_RS04030 19700f66cf10260a4783c61b7c542084 100 SUPERFAMILY SSF82771 5 79 5.62E-11 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CDW54_RS04030 19700f66cf10260a4783c61b7c542084 100 SMART SM00465 4 84 2.8E-4 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CDW54_RS04030 19700f66cf10260a4783c61b7c542084 100 Pfam PF01541 GIY-YIG catalytic domain 5 78 2.2E-17 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CDW54_RS04985 579b3f7477f56c3cd43a043acde87be7 226 SUPERFAMILY SSF52540 3 213 8.49E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS04985 579b3f7477f56c3cd43a043acde87be7 226 Pfam PF00005 ABC transporter 19 165 1.6E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS04985 579b3f7477f56c3cd43a043acde87be7 226 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS04985 579b3f7477f56c3cd43a043acde87be7 226 SMART SM00382 28 215 3.6E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS04985 579b3f7477f56c3cd43a043acde87be7 226 Gene3D G3DSA:3.40.50.300 2 220 6.5E-54 T 28-03-2018 CDW54_RS10345 01329472190bc256de1e2a8cd0594004 296 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 1 281 2.5E-88 T 28-03-2018 IPR011862 Phosphate binding protein GO:0006810 CDW54_RS10345 01329472190bc256de1e2a8cd0594004 296 Pfam PF12849 PBP superfamily domain 35 268 7.9E-37 T 28-03-2018 IPR024370 PBP domain CDW54_RS10345 01329472190bc256de1e2a8cd0594004 296 SUPERFAMILY SSF53850 43 289 8.09E-74 T 28-03-2018 CDW54_RS10345 01329472190bc256de1e2a8cd0594004 296 Gene3D G3DSA:3.40.190.10 38 175 8.0E-31 T 28-03-2018 CDW54_RS10345 01329472190bc256de1e2a8cd0594004 296 Gene3D G3DSA:3.40.190.10 176 294 1.9E-17 T 28-03-2018 CDW54_RS00430 ca80be8914f9d7f14d7f1c9c7daf42ae 431 ProSitePatterns PS00163 Fumarate lyases signature. 261 270 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CDW54_RS00430 ca80be8914f9d7f14d7f1c9c7daf42ae 431 PRINTS PR00145 Argininosuccinate lyase family signature 216 240 1.1E-10 T 28-03-2018 CDW54_RS00430 ca80be8914f9d7f14d7f1c9c7daf42ae 431 PRINTS PR00145 Argininosuccinate lyase family signature 128 148 1.1E-10 T 28-03-2018 CDW54_RS00430 ca80be8914f9d7f14d7f1c9c7daf42ae 431 PRINTS PR00145 Argininosuccinate lyase family signature 261 277 1.1E-10 T 28-03-2018 CDW54_RS00430 ca80be8914f9d7f14d7f1c9c7daf42ae 431 SMART SM00998 349 429 8.8E-41 T 28-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CDW54_RS00430 ca80be8914f9d7f14d7f1c9c7daf42ae 431 Gene3D G3DSA:1.10.275.10 2 92 1.1E-24 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal CDW54_RS00430 ca80be8914f9d7f14d7f1c9c7daf42ae 431 Pfam PF10397 Adenylosuccinate lyase C-terminus 350 428 4.6E-25 T 28-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CDW54_RS00430 ca80be8914f9d7f14d7f1c9c7daf42ae 431 PRINTS PR00149 Fumarate lyase superfamily signature 261 277 4.8E-27 T 28-03-2018 IPR000362 Fumarate lyase family CDW54_RS00430 ca80be8914f9d7f14d7f1c9c7daf42ae 431 PRINTS PR00149 Fumarate lyase superfamily signature 88 106 4.8E-27 T 28-03-2018 IPR000362 Fumarate lyase family CDW54_RS00430 ca80be8914f9d7f14d7f1c9c7daf42ae 431 PRINTS PR00149 Fumarate lyase superfamily signature 216 243 4.8E-27 T 28-03-2018 IPR000362 Fumarate lyase family CDW54_RS00430 ca80be8914f9d7f14d7f1c9c7daf42ae 431 PRINTS PR00149 Fumarate lyase superfamily signature 133 151 4.8E-27 T 28-03-2018 IPR000362 Fumarate lyase family CDW54_RS00430 ca80be8914f9d7f14d7f1c9c7daf42ae 431 Pfam PF00206 Lyase 6 286 1.5E-72 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal CDW54_RS00430 ca80be8914f9d7f14d7f1c9c7daf42ae 431 SUPERFAMILY SSF48557 3 428 2.2E-138 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 CDW54_RS00430 ca80be8914f9d7f14d7f1c9c7daf42ae 431 Gene3D G3DSA:1.10.40.30 349 428 1.8E-25 T 28-03-2018 CDW54_RS00430 ca80be8914f9d7f14d7f1c9c7daf42ae 431 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 1 428 7.6E-173 T 28-03-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CDW54_RS00430 ca80be8914f9d7f14d7f1c9c7daf42ae 431 Gene3D G3DSA:1.20.200.10 93 348 3.8E-78 T 28-03-2018 CDW54_RS09525 da498b300586cc8d48abf670ba6c0f61 206 Pfam PF05066 HB1, ASXL, restriction endonuclease HTH domain 15 81 1.0E-14 T 28-03-2018 IPR007759 HB1/Asxl, restriction endonuclease HTH domain GO:0006351|GO:0006355 CDW54_RS09525 da498b300586cc8d48abf670ba6c0f61 206 Hamap MF_00357 Probable DNA-directed RNA polymerase subunit delta [rpoE]. 9 198 15.171 T 28-03-2018 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 CDW54_RS09525 da498b300586cc8d48abf670ba6c0f61 206 TIGRFAM TIGR04567 RNAP_delt_lowGC: DNA-directed RNA polymerase delta subunit 13 93 1.6E-34 T 28-03-2018 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 CDW54_RS12440 c2ac11605fa9f19d94d83d8c563ecda1 382 Pfam PF16916 Dimerisation domain of Zinc Transporter 223 297 1.3E-16 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CDW54_RS12440 c2ac11605fa9f19d94d83d8c563ecda1 382 Gene3D G3DSA:3.30.70.1350 217 303 2.5E-14 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CDW54_RS12440 c2ac11605fa9f19d94d83d8c563ecda1 382 Gene3D G3DSA:3.30.70.1350 304 379 1.4E-4 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CDW54_RS12440 c2ac11605fa9f19d94d83d8c563ecda1 382 SUPERFAMILY SSF161111 18 218 5.62E-50 T 28-03-2018 CDW54_RS12440 c2ac11605fa9f19d94d83d8c563ecda1 382 Pfam PF01545 Cation efflux family 25 217 3.9E-43 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CDW54_RS12440 c2ac11605fa9f19d94d83d8c563ecda1 382 SUPERFAMILY SSF160240 221 299 5.89E-16 T 28-03-2018 CDW54_RS12440 c2ac11605fa9f19d94d83d8c563ecda1 382 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 25 286 1.1E-63 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CDW54_RS12440 c2ac11605fa9f19d94d83d8c563ecda1 382 Gene3D G3DSA:1.20.1510.10 23 216 2.7E-38 T 28-03-2018 CDW54_RS12540 6f50210934b9fbd9d3a6321babc20bbe 793 Pfam PF00912 Transglycosylase 91 267 6.1E-59 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CDW54_RS12540 6f50210934b9fbd9d3a6321babc20bbe 793 SUPERFAMILY SSF53955 81 293 5.34E-67 T 28-03-2018 IPR023346 Lysozyme-like domain CDW54_RS12540 6f50210934b9fbd9d3a6321babc20bbe 793 Pfam PF00905 Penicillin binding protein transpeptidase domain 363 653 1.4E-35 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CDW54_RS12540 6f50210934b9fbd9d3a6321babc20bbe 793 Gene3D G3DSA:3.40.710.10 290 745 4.2E-86 T 28-03-2018 CDW54_RS12540 6f50210934b9fbd9d3a6321babc20bbe 793 SUPERFAMILY SSF56601 249 271 1.5E-95 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CDW54_RS12540 6f50210934b9fbd9d3a6321babc20bbe 793 SUPERFAMILY SSF56601 304 679 1.5E-95 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CDW54_RS12540 6f50210934b9fbd9d3a6321babc20bbe 793 Gene3D G3DSA:1.10.3810.10 83 284 2.4E-70 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CDW54_RS12540 6f50210934b9fbd9d3a6321babc20bbe 793 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 101 657 8.2E-168 T 28-03-2018 CDW54_RS00330 10f9604f8451b748e85067c5819403fd 474 Gene3D G3DSA:3.90.1150.10 357 468 1.2E-9 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDW54_RS00330 10f9604f8451b748e85067c5819403fd 474 Gene3D G3DSA:3.40.640.10 152 356 2.2E-40 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDW54_RS00330 10f9604f8451b748e85067c5819403fd 474 SUPERFAMILY SSF46785 9 86 1.74E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS00330 10f9604f8451b748e85067c5819403fd 474 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 75 2.7E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDW54_RS00330 10f9604f8451b748e85067c5819403fd 474 Gene3D G3DSA:1.10.10.10 3 77 8.7E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS00330 10f9604f8451b748e85067c5819403fd 474 Pfam PF00155 Aminotransferase class I and II 156 457 8.3E-26 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CDW54_RS00330 10f9604f8451b748e85067c5819403fd 474 SMART SM00345 16 75 1.4E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDW54_RS00330 10f9604f8451b748e85067c5819403fd 474 SUPERFAMILY SSF53383 115 463 4.64E-65 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDW54_RS00330 10f9604f8451b748e85067c5819403fd 474 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 49 9.7E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDW54_RS00330 10f9604f8451b748e85067c5819403fd 474 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 65 9.7E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDW54_RS01675 514fdba5d453900452b7629d0d037eca 392 Pfam PF14815 NUDIX domain 245 380 1.1E-13 T 28-03-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CDW54_RS01675 514fdba5d453900452b7629d0d037eca 392 Gene3D G3DSA:3.90.79.10 234 391 1.2E-16 T 28-03-2018 CDW54_RS01675 514fdba5d453900452b7629d0d037eca 392 Gene3D G3DSA:1.10.340.30 30 126 2.2E-32 T 28-03-2018 CDW54_RS01675 514fdba5d453900452b7629d0d037eca 392 Pfam PF00633 Helix-hairpin-helix motif 108 137 6.6E-7 T 28-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 CDW54_RS01675 514fdba5d453900452b7629d0d037eca 392 SUPERFAMILY SSF55811 229 383 4.06E-19 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CDW54_RS01675 514fdba5d453900452b7629d0d037eca 392 Gene3D G3DSA:1.10.1670.10 127 233 3.5E-37 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CDW54_RS01675 514fdba5d453900452b7629d0d037eca 392 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 201 217 - T 28-03-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CDW54_RS01675 514fdba5d453900452b7629d0d037eca 392 SMART SM00525 200 220 4.3E-5 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CDW54_RS01675 514fdba5d453900452b7629d0d037eca 392 SMART SM00478 48 199 7.8E-51 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CDW54_RS01675 514fdba5d453900452b7629d0d037eca 392 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 44 175 2.7E-20 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CDW54_RS01675 514fdba5d453900452b7629d0d037eca 392 SUPERFAMILY SSF48150 14 231 1.51E-77 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CDW54_RS01675 514fdba5d453900452b7629d0d037eca 392 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 201 217 2.6E-4 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CDW54_RS01675 514fdba5d453900452b7629d0d037eca 392 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 16 278 2.0E-104 T 28-03-2018 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 CDW54_RS04970 f79f7d400c000257931d1458579f1a0c 457 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 394 428 8.0E-6 T 28-03-2018 IPR001451 Hexapeptide repeat CDW54_RS04970 f79f7d400c000257931d1458579f1a0c 457 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 304 351 8.1E-6 T 28-03-2018 IPR001451 Hexapeptide repeat CDW54_RS04970 f79f7d400c000257931d1458579f1a0c 457 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 267 299 1.8E-8 T 28-03-2018 IPR001451 Hexapeptide repeat CDW54_RS04970 f79f7d400c000257931d1458579f1a0c 457 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 6 452 1.8E-179 T 28-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 CDW54_RS04970 f79f7d400c000257931d1458579f1a0c 457 Pfam PF00483 Nucleotidyl transferase 6 221 1.8E-25 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CDW54_RS04970 f79f7d400c000257931d1458579f1a0c 457 SUPERFAMILY SSF51161 256 446 2.72E-47 T 28-03-2018 IPR011004 Trimeric LpxA-like CDW54_RS04970 f79f7d400c000257931d1458579f1a0c 457 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 3 452 41.668 T 28-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 CDW54_RS04970 f79f7d400c000257931d1458579f1a0c 457 Gene3D G3DSA:3.90.550.10 3 240 1.5E-63 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDW54_RS04970 f79f7d400c000257931d1458579f1a0c 457 SUPERFAMILY SSF53448 5 253 7.66E-67 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDW54_RS04970 f79f7d400c000257931d1458579f1a0c 457 Gene3D G3DSA:2.160.10.10 343 455 7.6E-21 T 28-03-2018 CDW54_RS04970 f79f7d400c000257931d1458579f1a0c 457 Gene3D G3DSA:2.160.10.10 241 342 8.9E-27 T 28-03-2018 CDW54_RS04970 f79f7d400c000257931d1458579f1a0c 457 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 403 431 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CDW54_RS09220 0e8e98ed21232bc4f487158d1aaa3be0 117 SUPERFAMILY SSF52833 6 101 3.08E-17 T 28-03-2018 IPR012336 Thioredoxin-like fold CDW54_RS09220 0e8e98ed21232bc4f487158d1aaa3be0 117 Pfam PF00085 Thioredoxin 11 94 5.3E-9 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 CDW54_RS09220 0e8e98ed21232bc4f487158d1aaa3be0 117 Gene3D G3DSA:3.40.30.10 1 105 1.4E-14 T 28-03-2018 CDW54_RS01450 2e3f00c414396e04d2a1a59cb09b9b13 646 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 641 34.151 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CDW54_RS01450 2e3f00c414396e04d2a1a59cb09b9b13 646 Gene3D G3DSA:3.10.20.30 1 63 4.2E-25 T 28-03-2018 IPR012675 Beta-grasp domain CDW54_RS01450 2e3f00c414396e04d2a1a59cb09b9b13 646 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 169 217 4.5E-15 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CDW54_RS01450 2e3f00c414396e04d2a1a59cb09b9b13 646 Pfam PF02824 TGS domain 2 61 1.2E-15 T 28-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 CDW54_RS01450 2e3f00c414396e04d2a1a59cb09b9b13 646 Gene3D G3DSA:3.30.980.10 65 145 1.1E-22 T 28-03-2018 CDW54_RS01450 2e3f00c414396e04d2a1a59cb09b9b13 646 Gene3D G3DSA:3.40.50.800 538 646 2.5E-26 T 28-03-2018 IPR004154 Anticodon-binding CDW54_RS01450 2e3f00c414396e04d2a1a59cb09b9b13 646 PRINTS PR01047 Threonyl-tRNA synthetase signature 363 386 2.9E-46 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CDW54_RS01450 2e3f00c414396e04d2a1a59cb09b9b13 646 PRINTS PR01047 Threonyl-tRNA synthetase signature 330 358 2.9E-46 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CDW54_RS01450 2e3f00c414396e04d2a1a59cb09b9b13 646 PRINTS PR01047 Threonyl-tRNA synthetase signature 469 497 2.9E-46 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CDW54_RS01450 2e3f00c414396e04d2a1a59cb09b9b13 646 PRINTS PR01047 Threonyl-tRNA synthetase signature 513 526 2.9E-46 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CDW54_RS01450 2e3f00c414396e04d2a1a59cb09b9b13 646 PRINTS PR01047 Threonyl-tRNA synthetase signature 540 552 2.9E-46 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CDW54_RS01450 2e3f00c414396e04d2a1a59cb09b9b13 646 SUPERFAMILY SSF52954 535 643 6.49E-30 T 28-03-2018 IPR004154 Anticodon-binding CDW54_RS01450 2e3f00c414396e04d2a1a59cb09b9b13 646 SUPERFAMILY SSF81271 2 61 1.94E-18 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CDW54_RS01450 2e3f00c414396e04d2a1a59cb09b9b13 646 SUPERFAMILY SSF55681 241 531 8.16E-95 T 28-03-2018 CDW54_RS01450 2e3f00c414396e04d2a1a59cb09b9b13 646 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 638 5.8E-226 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CDW54_RS01450 2e3f00c414396e04d2a1a59cb09b9b13 646 Pfam PF03129 Anticodon binding domain 547 635 6.2E-21 T 28-03-2018 IPR004154 Anticodon-binding CDW54_RS01450 2e3f00c414396e04d2a1a59cb09b9b13 646 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 325 535 2.2E-30 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDW54_RS01450 2e3f00c414396e04d2a1a59cb09b9b13 646 Gene3D G3DSA:3.30.54.20 146 185 1.7E-21 T 28-03-2018 CDW54_RS01450 2e3f00c414396e04d2a1a59cb09b9b13 646 SMART SM00863 168 217 1.4E-24 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CDW54_RS01450 2e3f00c414396e04d2a1a59cb09b9b13 646 SUPERFAMILY SSF55186 64 239 2.22E-63 T 28-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CDW54_RS01450 2e3f00c414396e04d2a1a59cb09b9b13 646 Gene3D G3DSA:3.30.930.10 219 537 1.4E-105 T 28-03-2018 CDW54_RS04840 f747fbbec6f84ec4addfa0b3e6b945bb 240 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 240 37.637 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDW54_RS04840 f747fbbec6f84ec4addfa0b3e6b945bb 240 Gene3D G3DSA:3.30.70.980 83 180 1.0E-31 T 28-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDW54_RS04840 f747fbbec6f84ec4addfa0b3e6b945bb 240 Gene3D G3DSA:3.30.70.980 181 239 1.4E-8 T 28-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDW54_RS04840 f747fbbec6f84ec4addfa0b3e6b945bb 240 Pfam PF01709 Transcriptional regulator 5 236 1.4E-96 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDW54_RS04840 f747fbbec6f84ec4addfa0b3e6b945bb 240 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 238 1.1E-101 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDW54_RS04840 f747fbbec6f84ec4addfa0b3e6b945bb 240 SUPERFAMILY SSF75625 3 239 1.05E-91 T 28-03-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDW54_RS04840 f747fbbec6f84ec4addfa0b3e6b945bb 240 Gene3D G3DSA:1.10.10.200 1 78 6.9E-33 T 28-03-2018 IPR017856 Integrase, N-terminal zinc-binding domain-like CDW54_RS08270 bda6a109195a5b7c427a4fd540b02fe1 315 SUPERFAMILY SSF53448 1 219 1.69E-40 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDW54_RS08270 bda6a109195a5b7c427a4fd540b02fe1 315 Gene3D G3DSA:3.90.550.10 1 213 7.0E-32 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDW54_RS08270 bda6a109195a5b7c427a4fd540b02fe1 315 Pfam PF00535 Glycosyl transferase family 2 4 163 5.6E-30 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CDW54_RS00140 d3b84d95d2689fc0e5da250b1ffcdc9a 212 SUPERFAMILY SSF54106 30 77 2.88E-8 T 28-03-2018 IPR018392 LysM domain CDW54_RS00140 d3b84d95d2689fc0e5da250b1ffcdc9a 212 SMART SM00257 30 77 3.2E-9 T 28-03-2018 IPR018392 LysM domain CDW54_RS00140 d3b84d95d2689fc0e5da250b1ffcdc9a 212 Pfam PF01476 LysM domain 31 77 5.9E-12 T 28-03-2018 IPR018392 LysM domain CDW54_RS00140 d3b84d95d2689fc0e5da250b1ffcdc9a 212 Gene3D G3DSA:3.10.350.10 24 92 4.2E-15 T 28-03-2018 CDW54_RS00255 ab21404717449a74ba364f7b65874ade 112 PIRSF PIRSF031653 7 106 8.7E-33 T 28-03-2018 IPR016979 Protein of unknown function DUF2129 CDW54_RS00255 ab21404717449a74ba364f7b65874ade 112 Hamap MF_01126 UPF0298 protein . 9 86 21.484 T 28-03-2018 IPR016979 Protein of unknown function DUF2129 CDW54_RS00255 ab21404717449a74ba364f7b65874ade 112 Pfam PF09902 Uncharacterized protein conserved in bacteria (DUF2129) 13 82 4.1E-30 T 28-03-2018 IPR016979 Protein of unknown function DUF2129 CDW54_RS12435 64d29450d06de098fc0f8ee0740f0977 137 Gene3D G3DSA:3.30.420.10 1 137 5.5E-23 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS12435 64d29450d06de098fc0f8ee0740f0977 137 SUPERFAMILY SSF53098 2 124 1.52E-22 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS12435 64d29450d06de098fc0f8ee0740f0977 137 Pfam PF13456 Reverse transcriptase-like 38 126 1.8E-8 T 28-03-2018 CDW54_RS11285 e5fab42c6000b045f119905e6c545afb 363 Gene3D G3DSA:1.10.3660.10 180 287 2.3E-23 T 28-03-2018 CDW54_RS11285 e5fab42c6000b045f119905e6c545afb 363 SUPERFAMILY SSF55021 292 341 8.02E-7 T 28-03-2018 CDW54_RS11285 e5fab42c6000b045f119905e6c545afb 363 SUPERFAMILY SSF48179 172 279 7.48E-33 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CDW54_RS11285 e5fab42c6000b045f119905e6c545afb 363 Gene3D G3DSA:3.30.70.260 289 358 7.9E-8 T 28-03-2018 CDW54_RS11285 e5fab42c6000b045f119905e6c545afb 363 Pfam PF01842 ACT domain 294 340 8.1E-8 T 28-03-2018 IPR002912 ACT domain CDW54_RS11285 e5fab42c6000b045f119905e6c545afb 363 Gene3D G3DSA:3.40.50.720 1 170 1.2E-21 T 28-03-2018 CDW54_RS11285 e5fab42c6000b045f119905e6c545afb 363 SUPERFAMILY SSF51735 5 160 4.71E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS11285 e5fab42c6000b045f119905e6c545afb 363 Pfam PF02153 Prephenate dehydrogenase 18 270 1.9E-73 T 28-03-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 CDW54_RS02570 49573e1fac7a34185e6251ee56595f73 881 Gene3D G3DSA:3.40.50.620 21 194 6.5E-30 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDW54_RS02570 49573e1fac7a34185e6251ee56595f73 881 Gene3D G3DSA:3.90.740.10 195 241 5.6E-14 T 28-03-2018 CDW54_RS02570 49573e1fac7a34185e6251ee56595f73 881 SUPERFAMILY SSF50677 195 346 4.58E-63 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CDW54_RS02570 49573e1fac7a34185e6251ee56595f73 881 SUPERFAMILY SSF46589 813 877 6.28E-17 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 CDW54_RS02570 49573e1fac7a34185e6251ee56595f73 881 SUPERFAMILY SSF52374 345 574 3.6E-142 T 28-03-2018 CDW54_RS02570 49573e1fac7a34185e6251ee56595f73 881 SUPERFAMILY SSF52374 6 197 3.6E-142 T 28-03-2018 CDW54_RS02570 49573e1fac7a34185e6251ee56595f73 881 PRINTS PR00986 Valyl-tRNA synthetase signature 235 252 6.7E-38 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CDW54_RS02570 49573e1fac7a34185e6251ee56595f73 881 PRINTS PR00986 Valyl-tRNA synthetase signature 476 494 6.7E-38 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CDW54_RS02570 49573e1fac7a34185e6251ee56595f73 881 PRINTS PR00986 Valyl-tRNA synthetase signature 350 363 6.7E-38 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CDW54_RS02570 49573e1fac7a34185e6251ee56595f73 881 PRINTS PR00986 Valyl-tRNA synthetase signature 41 52 6.7E-38 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CDW54_RS02570 49573e1fac7a34185e6251ee56595f73 881 PRINTS PR00986 Valyl-tRNA synthetase signature 444 465 6.7E-38 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CDW54_RS02570 49573e1fac7a34185e6251ee56595f73 881 Gene3D G3DSA:1.10.287.380 806 876 1.0E-25 T 28-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 CDW54_RS02570 49573e1fac7a34185e6251ee56595f73 881 Pfam PF08264 Anticodon-binding domain of tRNA 607 753 3.1E-45 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CDW54_RS02570 49573e1fac7a34185e6251ee56595f73 881 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 48 59 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDW54_RS02570 49573e1fac7a34185e6251ee56595f73 881 SUPERFAMILY SSF47323 575 828 5.98E-77 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDW54_RS02570 49573e1fac7a34185e6251ee56595f73 881 Gene3D G3DSA:1.10.730.10 522 746 5.0E-80 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDW54_RS02570 49573e1fac7a34185e6251ee56595f73 881 Hamap MF_02004 Valine--tRNA ligase [valS]. 7 878 16.106 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CDW54_RS02570 49573e1fac7a34185e6251ee56595f73 881 Gene3D G3DSA:3.90.740.10 242 434 5.0E-67 T 28-03-2018 CDW54_RS02570 49573e1fac7a34185e6251ee56595f73 881 Gene3D G3DSA:3.40.50.620 435 521 6.5E-30 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDW54_RS02570 49573e1fac7a34185e6251ee56595f73 881 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 813 877 2.5E-24 T 28-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 CDW54_RS02570 49573e1fac7a34185e6251ee56595f73 881 TIGRFAM TIGR00422 valS: valine--tRNA ligase 8 860 0.0 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CDW54_RS02570 49573e1fac7a34185e6251ee56595f73 881 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 20 564 4.3E-225 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDW54_RS04075 77e595e3c2d968b684cfdc7385fe29a8 737 Pfam PF04607 Region found in RelA / SpoT proteins 240 350 1.4E-40 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 CDW54_RS04075 77e595e3c2d968b684cfdc7385fe29a8 737 SUPERFAMILY SSF55021 661 734 2.15E-10 T 28-03-2018 CDW54_RS04075 77e595e3c2d968b684cfdc7385fe29a8 737 SMART SM00471 46 158 6.4E-9 T 28-03-2018 IPR003607 HD/PDEase domain CDW54_RS04075 77e595e3c2d968b684cfdc7385fe29a8 737 Gene3D G3DSA:3.10.20.30 389 461 2.6E-24 T 28-03-2018 IPR012675 Beta-grasp domain CDW54_RS04075 77e595e3c2d968b684cfdc7385fe29a8 737 Gene3D G3DSA:3.30.70.260 657 737 1.8E-9 T 28-03-2018 CDW54_RS04075 77e595e3c2d968b684cfdc7385fe29a8 737 Pfam PF13291 ACT domain 657 734 1.2E-22 T 28-03-2018 IPR002912 ACT domain CDW54_RS04075 77e595e3c2d968b684cfdc7385fe29a8 737 SUPERFAMILY SSF109604 13 196 5.02E-78 T 28-03-2018 CDW54_RS04075 77e595e3c2d968b684cfdc7385fe29a8 737 Pfam PF13328 HD domain 31 180 9.1E-53 T 28-03-2018 IPR003607 HD/PDEase domain CDW54_RS04075 77e595e3c2d968b684cfdc7385fe29a8 737 Gene3D G3DSA:3.30.460.10 193 330 4.4E-45 T 28-03-2018 CDW54_RS04075 77e595e3c2d968b684cfdc7385fe29a8 737 SMART SM00954 240 350 1.6E-69 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 CDW54_RS04075 77e595e3c2d968b684cfdc7385fe29a8 737 SUPERFAMILY SSF81271 382 454 1.96E-23 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CDW54_RS04075 77e595e3c2d968b684cfdc7385fe29a8 737 SUPERFAMILY SSF81301 185 399 8.34E-66 T 28-03-2018 CDW54_RS04075 77e595e3c2d968b684cfdc7385fe29a8 737 Pfam PF02824 TGS domain 395 454 2.0E-22 T 28-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 CDW54_RS04075 77e595e3c2d968b684cfdc7385fe29a8 737 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 31 734 1.8E-253 T 28-03-2018 IPR004811 RelA/SpoT family GO:0015969 CDW54_RS01765 2c605ae9f67384a10456993afd42a711 159 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 19 50 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CDW54_RS01765 2c605ae9f67384a10456993afd42a711 159 SUPERFAMILY SSF54534 82 157 2.49E-22 T 28-03-2018 CDW54_RS01765 2c605ae9f67384a10456993afd42a711 159 PIRSF PIRSF006092 1 159 2.4E-51 T 28-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 CDW54_RS01765 2c605ae9f67384a10456993afd42a711 159 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 7 157 1.9E-58 T 28-03-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 CDW54_RS01765 2c605ae9f67384a10456993afd42a711 159 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 84 157 4.5E-28 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CDW54_RS01765 2c605ae9f67384a10456993afd42a711 159 Hamap MF_00105 Transcription elongation factor GreA [greA]. 4 157 32.801 T 28-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 CDW54_RS01765 2c605ae9f67384a10456993afd42a711 159 SUPERFAMILY SSF46557 5 79 7.32E-27 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CDW54_RS01765 2c605ae9f67384a10456993afd42a711 159 Gene3D G3DSA:3.10.50.30 79 159 7.0E-26 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CDW54_RS01765 2c605ae9f67384a10456993afd42a711 159 Gene3D G3DSA:1.10.287.180 5 78 6.6E-30 T 28-03-2018 CDW54_RS01765 2c605ae9f67384a10456993afd42a711 159 Pfam PF03449 Transcription elongation factor, N-terminal 7 76 4.2E-29 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CDW54_RS01765 2c605ae9f67384a10456993afd42a711 159 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 122 138 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CDW54_RS01575 4be57e9c4a7efb06ad217f891a24bffd 146 SUPERFAMILY SSF46785 11 144 1.9E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS01575 4be57e9c4a7efb06ad217f891a24bffd 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 4.9E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDW54_RS01575 4be57e9c4a7efb06ad217f891a24bffd 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 118 138 4.9E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDW54_RS01575 4be57e9c4a7efb06ad217f891a24bffd 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 52 68 4.9E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDW54_RS01575 4be57e9c4a7efb06ad217f891a24bffd 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 4.9E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDW54_RS01575 4be57e9c4a7efb06ad217f891a24bffd 146 SMART SM00347 28 128 1.6E-18 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDW54_RS01575 4be57e9c4a7efb06ad217f891a24bffd 146 Gene3D G3DSA:1.10.10.10 6 146 3.9E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS01575 4be57e9c4a7efb06ad217f891a24bffd 146 Pfam PF01047 MarR family 35 93 4.4E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDW54_RS00155 fa0c005ae61bb0e9d11b1adc56e2c251 114 Gene3D G3DSA:3.30.300.130 13 113 1.2E-26 T 28-03-2018 IPR034904 Fe-S cluster assembly domain CDW54_RS00155 fa0c005ae61bb0e9d11b1adc56e2c251 114 Pfam PF01883 Iron-sulfur cluster assembly protein 17 91 5.6E-21 T 28-03-2018 IPR002744 MIP18 family-like CDW54_RS00155 fa0c005ae61bb0e9d11b1adc56e2c251 114 SUPERFAMILY SSF117916 15 112 1.34E-30 T 28-03-2018 IPR034904 Fe-S cluster assembly domain CDW54_RS02495 732d16e09ec89fcee4ef26413b0a122e 305 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 4 284 1.4E-93 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CDW54_RS02495 732d16e09ec89fcee4ef26413b0a122e 305 SUPERFAMILY SSF52540 139 226 9.86E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS02495 732d16e09ec89fcee4ef26413b0a122e 305 SUPERFAMILY SSF52540 3 36 9.86E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS02495 732d16e09ec89fcee4ef26413b0a122e 305 Gene3D G3DSA:3.40.50.300 1 153 4.2E-55 T 28-03-2018 CDW54_RS02495 732d16e09ec89fcee4ef26413b0a122e 305 Gene3D G3DSA:1.10.287.890 197 275 9.9E-28 T 28-03-2018 CDW54_RS02495 732d16e09ec89fcee4ef26413b0a122e 305 SUPERFAMILY SSF52540 5 150 3.16E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS02495 732d16e09ec89fcee4ef26413b0a122e 305 Pfam PF01715 IPP transferase 37 277 1.7E-82 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CDW54_RS02495 732d16e09ec89fcee4ef26413b0a122e 305 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 4 299 29.631 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CDW54_RS03165 5669b02f660299eaa7cd3fc40c8be898 258 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 CDW54_RS03165 5669b02f660299eaa7cd3fc40c8be898 258 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 2 253 5.3E-90 T 28-03-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 CDW54_RS03165 5669b02f660299eaa7cd3fc40c8be898 258 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 189 205 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 CDW54_RS03165 5669b02f660299eaa7cd3fc40c8be898 258 Gene3D G3DSA:3.20.20.140 1 258 8.0E-93 T 28-03-2018 CDW54_RS03165 5669b02f660299eaa7cd3fc40c8be898 258 Pfam PF01026 TatD related DNase 3 253 8.7E-86 T 28-03-2018 IPR001130 TatD family GO:0016788 CDW54_RS03165 5669b02f660299eaa7cd3fc40c8be898 258 PIRSF PIRSF005902 1 257 4.8E-89 T 28-03-2018 IPR001130 TatD family GO:0016788 CDW54_RS03165 5669b02f660299eaa7cd3fc40c8be898 258 ProSitePatterns PS01090 TatD deoxyribonuclease family signature 2. 124 134 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 CDW54_RS03165 5669b02f660299eaa7cd3fc40c8be898 258 SUPERFAMILY SSF51556 1 254 1.08E-95 T 28-03-2018 IPR032466 Metal-dependent hydrolase CDW54_RS07875 4b4825d01d1e16935c8e9a6e9abb83f8 381 SUPERFAMILY SSF53383 4 379 8.76E-121 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDW54_RS07875 4b4825d01d1e16935c8e9a6e9abb83f8 381 Gene3D G3DSA:3.40.640.10 1 245 1.2E-55 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDW54_RS07875 4b4825d01d1e16935c8e9a6e9abb83f8 381 Gene3D G3DSA:3.90.1150.10 246 381 2.2E-53 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDW54_RS07875 4b4825d01d1e16935c8e9a6e9abb83f8 381 PIRSF PIRSF001434 1 380 6.7E-146 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CDW54_RS07875 4b4825d01d1e16935c8e9a6e9abb83f8 381 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 4 376 1.1E-156 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CDW54_RS07875 4b4825d01d1e16935c8e9a6e9abb83f8 381 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 187 201 - T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CDW54_RS02385 899eb2598d0b0e874630254f4ffa6a73 218 SUPERFAMILY SSF51206 7 136 1.13E-23 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like CDW54_RS02385 899eb2598d0b0e874630254f4ffa6a73 218 SUPERFAMILY SSF46785 139 217 5.33E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS02385 899eb2598d0b0e874630254f4ffa6a73 218 Gene3D G3DSA:2.60.120.10 8 130 4.3E-10 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CDW54_RS02385 899eb2598d0b0e874630254f4ffa6a73 218 ProSitePatterns PS00042 Crp-type HTH domain signature. 167 191 - T 28-03-2018 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 CDW54_RS02385 899eb2598d0b0e874630254f4ffa6a73 218 Gene3D G3DSA:1.10.10.10 131 217 2.0E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS02385 899eb2598d0b0e874630254f4ffa6a73 218 Pfam PF13545 Crp-like helix-turn-helix domain 141 214 6.8E-15 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CDW54_RS02385 899eb2598d0b0e874630254f4ffa6a73 218 SMART SM00419 159 208 9.9E-10 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CDW54_RS03755 4bd3171a25d5d7f327224456c53e7851 214 Pfam PF02080 TrkA-C domain 140 206 2.2E-10 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CDW54_RS03755 4bd3171a25d5d7f327224456c53e7851 214 SUPERFAMILY SSF116726 136 206 4.71E-13 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CDW54_RS03755 4bd3171a25d5d7f327224456c53e7851 214 Gene3D G3DSA:3.30.70.1450 132 213 3.3E-10 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CDW54_RS03755 4bd3171a25d5d7f327224456c53e7851 214 SUPERFAMILY SSF46785 9 83 2.72E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS03755 4bd3171a25d5d7f327224456c53e7851 214 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 3.2E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDW54_RS03755 4bd3171a25d5d7f327224456c53e7851 214 Gene3D G3DSA:1.10.10.10 1 76 2.4E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS03755 4bd3171a25d5d7f327224456c53e7851 214 SMART SM00345 15 74 4.9E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDW54_RS09570 8d1befd73092858502a2a84be89f9675 396 Pfam PF00162 Phosphoglycerate kinase 6 385 1.3E-158 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDW54_RS09570 8d1befd73092858502a2a84be89f9675 396 Gene3D G3DSA:3.40.50.1260 185 383 5.7E-82 T 28-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDW54_RS09570 8d1befd73092858502a2a84be89f9675 396 PRINTS PR00477 Phosphoglycerate kinase family signature 314 339 1.8E-96 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDW54_RS09570 8d1befd73092858502a2a84be89f9675 396 PRINTS PR00477 Phosphoglycerate kinase family signature 348 359 1.8E-96 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDW54_RS09570 8d1befd73092858502a2a84be89f9675 396 PRINTS PR00477 Phosphoglycerate kinase family signature 196 215 1.8E-96 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDW54_RS09570 8d1befd73092858502a2a84be89f9675 396 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 1.8E-96 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDW54_RS09570 8d1befd73092858502a2a84be89f9675 396 PRINTS PR00477 Phosphoglycerate kinase family signature 110 125 1.8E-96 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDW54_RS09570 8d1befd73092858502a2a84be89f9675 396 PRINTS PR00477 Phosphoglycerate kinase family signature 173 195 1.8E-96 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDW54_RS09570 8d1befd73092858502a2a84be89f9675 396 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 1.8E-96 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDW54_RS09570 8d1befd73092858502a2a84be89f9675 396 PRINTS PR00477 Phosphoglycerate kinase family signature 371 388 1.8E-96 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDW54_RS09570 8d1befd73092858502a2a84be89f9675 396 PRINTS PR00477 Phosphoglycerate kinase family signature 142 164 1.8E-96 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDW54_RS09570 8d1befd73092858502a2a84be89f9675 396 PIRSF PIRSF000724 1 396 5.8E-145 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDW54_RS09570 8d1befd73092858502a2a84be89f9675 396 SUPERFAMILY SSF53748 1 395 9.42E-154 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDW54_RS09570 8d1befd73092858502a2a84be89f9675 396 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 8 395 41.994 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDW54_RS09570 8d1befd73092858502a2a84be89f9675 396 Gene3D G3DSA:3.40.50.1260 3 184 5.3E-71 T 28-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDW54_RS09570 8d1befd73092858502a2a84be89f9675 396 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 15 25 - T 28-03-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDW54_RS05660 b00e0da932e391748949b1406fd85bed 44 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 28-03-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS05660 b00e0da932e391748949b1406fd85bed 44 Pfam PF00468 Ribosomal protein L34 1 44 3.0E-23 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS05660 b00e0da932e391748949b1406fd85bed 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 16.018 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS05660 b00e0da932e391748949b1406fd85bed 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 44 6.2E-20 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS05660 b00e0da932e391748949b1406fd85bed 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 42 1.0E-15 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS07740 0d54dad833a93f0136899dc1b257a804 131 Gene3D G3DSA:3.40.1650.10 1 131 1.6E-34 T 28-03-2018 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 CDW54_RS07740 0d54dad833a93f0136899dc1b257a804 131 Hamap MF_01661 D-ribose pyranase [rbsD]. 1 131 30.996 T 28-03-2018 IPR023064 D-ribose pyranase GO:0016872 CDW54_RS07740 0d54dad833a93f0136899dc1b257a804 131 Pfam PF05025 RbsD / FucU transport protein family 1 130 2.9E-45 T 28-03-2018 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 CDW54_RS07740 0d54dad833a93f0136899dc1b257a804 131 SUPERFAMILY SSF102546 1 131 8.5E-45 T 28-03-2018 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 CDW54_RS08400 e472c853c825e0aced0ebf65bbaba70b 135 Gene3D G3DSA:1.20.120.590 4 131 1.9E-65 T 28-03-2018 IPR021571 Protein of unknown function DUF3206 CDW54_RS08400 e472c853c825e0aced0ebf65bbaba70b 135 Pfam PF11472 Protein of unknown function (DUF3206) 4 131 2.7E-52 T 28-03-2018 IPR021571 Protein of unknown function DUF3206 CDW54_RS08400 e472c853c825e0aced0ebf65bbaba70b 135 SUPERFAMILY SSF140607 2 133 6.28E-51 T 28-03-2018 IPR021571 Protein of unknown function DUF3206 CDW54_RS10235 8b50e9bb7639dda8e8eae712b3ea34eb 693 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 170 662 2.1E-76 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDW54_RS10235 8b50e9bb7639dda8e8eae712b3ea34eb 693 SUPERFAMILY SSF56784 393 413 1.61E-57 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS10235 8b50e9bb7639dda8e8eae712b3ea34eb 693 SUPERFAMILY SSF56784 447 684 1.61E-57 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS10235 8b50e9bb7639dda8e8eae712b3ea34eb 693 SUPERFAMILY SSF81653 196 293 1.7E-22 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CDW54_RS10235 8b50e9bb7639dda8e8eae712b3ea34eb 693 Gene3D G3DSA:3.30.70.100 2 86 1.3E-12 T 28-03-2018 CDW54_RS10235 8b50e9bb7639dda8e8eae712b3ea34eb 693 ProSitePatterns PS01047 Heavy-metal-associated domain. 6 35 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CDW54_RS10235 8b50e9bb7639dda8e8eae712b3ea34eb 693 SUPERFAMILY SSF55008 3 63 3.27E-12 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CDW54_RS10235 8b50e9bb7639dda8e8eae712b3ea34eb 693 Gene3D G3DSA:3.40.50.1000 505 656 2.1E-37 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS10235 8b50e9bb7639dda8e8eae712b3ea34eb 693 Pfam PF00702 haloacid dehalogenase-like hydrolase 392 597 7.2E-35 T 28-03-2018 CDW54_RS10235 8b50e9bb7639dda8e8eae712b3ea34eb 693 PRINTS PR00941 Cadmium-transporting ATPase signature 123 135 6.1E-15 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CDW54_RS10235 8b50e9bb7639dda8e8eae712b3ea34eb 693 PRINTS PR00941 Cadmium-transporting ATPase signature 178 198 6.1E-15 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CDW54_RS10235 8b50e9bb7639dda8e8eae712b3ea34eb 693 PRINTS PR00941 Cadmium-transporting ATPase signature 278 292 6.1E-15 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CDW54_RS10235 8b50e9bb7639dda8e8eae712b3ea34eb 693 PRINTS PR00941 Cadmium-transporting ATPase signature 15 36 6.1E-15 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CDW54_RS10235 8b50e9bb7639dda8e8eae712b3ea34eb 693 PRINTS PR00941 Cadmium-transporting ATPase signature 4 13 6.1E-15 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CDW54_RS10235 8b50e9bb7639dda8e8eae712b3ea34eb 693 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 243 257 2.4E-22 T 28-03-2018 CDW54_RS10235 8b50e9bb7639dda8e8eae712b3ea34eb 693 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 583 602 2.4E-22 T 28-03-2018 CDW54_RS10235 8b50e9bb7639dda8e8eae712b3ea34eb 693 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 607 619 2.4E-22 T 28-03-2018 CDW54_RS10235 8b50e9bb7639dda8e8eae712b3ea34eb 693 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 529 539 2.4E-22 T 28-03-2018 CDW54_RS10235 8b50e9bb7639dda8e8eae712b3ea34eb 693 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 395 409 2.4E-22 T 28-03-2018 CDW54_RS10235 8b50e9bb7639dda8e8eae712b3ea34eb 693 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 144 687 1.0E-155 T 28-03-2018 CDW54_RS10235 8b50e9bb7639dda8e8eae712b3ea34eb 693 Pfam PF00403 Heavy-metal-associated domain 4 63 1.3E-12 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CDW54_RS10235 8b50e9bb7639dda8e8eae712b3ea34eb 693 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 144 685 3.4E-169 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CDW54_RS10235 8b50e9bb7639dda8e8eae712b3ea34eb 693 Gene3D G3DSA:3.40.1110.10 409 504 2.0E-17 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CDW54_RS10235 8b50e9bb7639dda8e8eae712b3ea34eb 693 Gene3D G3DSA:1.20.1110.10 87 408 9.4E-33 T 28-03-2018 CDW54_RS10235 8b50e9bb7639dda8e8eae712b3ea34eb 693 Pfam PF00122 E1-E2 ATPase 194 373 4.6E-47 T 28-03-2018 CDW54_RS10235 8b50e9bb7639dda8e8eae712b3ea34eb 693 SUPERFAMILY SSF81665 633 672 1.83E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CDW54_RS10235 8b50e9bb7639dda8e8eae712b3ea34eb 693 SUPERFAMILY SSF81665 294 389 1.83E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CDW54_RS10235 8b50e9bb7639dda8e8eae712b3ea34eb 693 SUPERFAMILY SSF81665 144 197 1.83E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CDW54_RS10235 8b50e9bb7639dda8e8eae712b3ea34eb 693 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 397 403 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CDW54_RS09915 0bb08c2ca72c2f92d2f2c186df00a1b6 594 Gene3D G3DSA:3.40.50.300 341 593 1.4E-67 T 28-03-2018 CDW54_RS09915 0bb08c2ca72c2f92d2f2c186df00a1b6 594 Pfam PF00664 ABC transporter transmembrane region 36 309 4.3E-40 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CDW54_RS09915 0bb08c2ca72c2f92d2f2c186df00a1b6 594 SUPERFAMILY SSF90123 19 340 1.23E-69 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CDW54_RS09915 0bb08c2ca72c2f92d2f2c186df00a1b6 594 SUPERFAMILY SSF52540 348 590 6.18E-86 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS09915 0bb08c2ca72c2f92d2f2c186df00a1b6 594 Gene3D G3DSA:1.20.1560.10 3 340 7.4E-64 T 28-03-2018 CDW54_RS09915 0bb08c2ca72c2f92d2f2c186df00a1b6 594 Pfam PF00005 ABC transporter 371 520 1.3E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS09915 0bb08c2ca72c2f92d2f2c186df00a1b6 594 ProSitePatterns PS00211 ABC transporters family signature. 492 506 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS09915 0bb08c2ca72c2f92d2f2c186df00a1b6 594 SMART SM00382 380 572 2.7E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS01880 70914a619dfe4994bb1a094159b6bd59 288 Pfam PF00483 Nucleotidyl transferase 2 238 2.2E-73 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CDW54_RS01880 70914a619dfe4994bb1a094159b6bd59 288 Gene3D G3DSA:3.90.550.10 1 288 2.9E-74 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDW54_RS01880 70914a619dfe4994bb1a094159b6bd59 288 SUPERFAMILY SSF53448 1 286 9.46E-96 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDW54_RS01880 70914a619dfe4994bb1a094159b6bd59 288 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 286 7.2E-157 T 28-03-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 CDW54_RS07090 db4ba6d13578815f2eb1ea6930597c9c 106 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 6 99 1.0E-23 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CDW54_RS07090 db4ba6d13578815f2eb1ea6930597c9c 106 SUPERFAMILY SSF52794 4 105 2.01E-37 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CDW54_RS07090 db4ba6d13578815f2eb1ea6930597c9c 106 Gene3D G3DSA:3.40.50.2300 5 106 6.7E-39 T 28-03-2018 CDW54_RS10185 ff855043dd35f8a6d89c410d13f3bb28 66 SUPERFAMILY SSF50249 1 64 6.12E-26 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDW54_RS10185 ff855043dd35f8a6d89c410d13f3bb28 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 4.0E-32 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CDW54_RS10185 ff855043dd35f8a6d89c410d13f3bb28 66 PIRSF PIRSF002599 1 66 2.5E-25 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 CDW54_RS10185 ff855043dd35f8a6d89c410d13f3bb28 66 SMART SM00357 3 66 4.8E-33 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CDW54_RS10185 ff855043dd35f8a6d89c410d13f3bb28 66 PRINTS PR00050 Cold shock protein signature 4 19 3.6E-19 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CDW54_RS10185 ff855043dd35f8a6d89c410d13f3bb28 66 PRINTS PR00050 Cold shock protein signature 39 57 3.6E-19 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CDW54_RS10185 ff855043dd35f8a6d89c410d13f3bb28 66 PRINTS PR00050 Cold shock protein signature 24 33 3.6E-19 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CDW54_RS10185 ff855043dd35f8a6d89c410d13f3bb28 66 Gene3D G3DSA:2.40.50.140 1 66 3.9E-30 T 28-03-2018 CDW54_RS10185 ff855043dd35f8a6d89c410d13f3bb28 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 28-03-2018 IPR019844 Cold-shock conserved site CDW54_RS09505 58c852da12a504f69f916afb65a4ab75 269 Gene3D G3DSA:3.40.50.1000 1 269 2.7E-49 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS09505 58c852da12a504f69f916afb65a4ab75 269 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 264 9.3E-70 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS09505 58c852da12a504f69f916afb65a4ab75 269 ProSitePatterns PS01229 Hypothetical cof family signature 2. 218 240 - T 28-03-2018 CDW54_RS09505 58c852da12a504f69f916afb65a4ab75 269 ProSitePatterns PS01228 Hypothetical cof family signature 1. 5 16 - T 28-03-2018 CDW54_RS09505 58c852da12a504f69f916afb65a4ab75 269 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 264 2.3E-71 T 28-03-2018 IPR000150 Cof family GO:0016787 CDW54_RS09505 58c852da12a504f69f916afb65a4ab75 269 SUPERFAMILY SSF56784 1 268 5.47E-79 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS09505 58c852da12a504f69f916afb65a4ab75 269 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 237 2.2E-35 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CDW54_RS03355 b396e4d20f49e2cf0a2321733e55a6ec 279 Gene3D G3DSA:1.10.8.10 4 82 2.9E-11 T 28-03-2018 CDW54_RS03355 b396e4d20f49e2cf0a2321733e55a6ec 279 Gene3D G3DSA:3.40.50.150 83 278 3.4E-44 T 28-03-2018 CDW54_RS03355 b396e4d20f49e2cf0a2321733e55a6ec 279 SUPERFAMILY SSF53335 6 275 3.06E-54 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDW54_RS03355 b396e4d20f49e2cf0a2321733e55a6ec 279 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 5 275 7.2E-66 T 28-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 CDW54_RS03355 b396e4d20f49e2cf0a2321733e55a6ec 279 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 6 279 40.92 T 28-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 CDW54_RS03355 b396e4d20f49e2cf0a2321733e55a6ec 279 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 182 188 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CDW54_RS03355 b396e4d20f49e2cf0a2321733e55a6ec 279 Pfam PF05175 Methyltransferase small domain 115 193 1.7E-18 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CDW54_RS03355 b396e4d20f49e2cf0a2321733e55a6ec 279 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 28 275 2.9E-86 T 28-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 CDW54_RS05035 af2520735a931a942a66379b95b0fe89 294 Pfam PF13464 Domain of unknown function (DUF4115) 212 289 1.7E-16 T 28-03-2018 IPR025194 Domain of unknown function DUF4115 CDW54_RS05035 af2520735a931a942a66379b95b0fe89 294 Gene3D G3DSA:1.10.260.40 3 191 2.5E-6 T 28-03-2018 CDW54_RS05035 af2520735a931a942a66379b95b0fe89 294 Pfam PF13413 Helix-turn-helix domain 10 69 2.8E-22 T 28-03-2018 CDW54_RS07715 21bef1771d1b37d91aed18a47dc6d366 346 SUPERFAMILY SSF74650 8 342 2.51E-97 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CDW54_RS07715 21bef1771d1b37d91aed18a47dc6d366 346 ProSitePatterns PS00545 Aldose 1-epimerase putative active site. 171 180 - T 28-03-2018 IPR018052 Aldose 1-epimerase, conserved site KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 CDW54_RS07715 21bef1771d1b37d91aed18a47dc6d366 346 PIRSF PIRSF005096 1 345 4.8E-101 T 28-03-2018 IPR015443 Aldose 1-epimerase GO:0016853|GO:0019318 KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 CDW54_RS07715 21bef1771d1b37d91aed18a47dc6d366 346 Gene3D G3DSA:2.70.98.10 1 346 2.2E-88 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CDW54_RS07715 21bef1771d1b37d91aed18a47dc6d366 346 Pfam PF01263 Aldose 1-epimerase 14 341 8.7E-72 T 28-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 CDW54_RS03605 b7ba7d5ee1070871ff8e9b6ce63bf5e1 490 SUPERFAMILY SSF54675 5 140 3.66E-50 T 28-03-2018 CDW54_RS03605 b7ba7d5ee1070871ff8e9b6ce63bf5e1 490 Gene3D G3DSA:3.20.140.10 4 389 7.6E-125 T 28-03-2018 CDW54_RS03605 b7ba7d5ee1070871ff8e9b6ce63bf5e1 490 SUPERFAMILY SSF51690 141 480 5.72E-131 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CDW54_RS03605 b7ba7d5ee1070871ff8e9b6ce63bf5e1 490 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 158 337 3.1E-8 T 28-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CDW54_RS03605 b7ba7d5ee1070871ff8e9b6ce63bf5e1 490 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 11 467 2.4E-184 T 28-03-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 CDW54_RS03605 b7ba7d5ee1070871ff8e9b6ce63bf5e1 490 PIRSF PIRSF000484 3 482 1.8E-145 T 28-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CDW54_RS04230 07ae304469c962b85daa6cb1128d671f 906 Pfam PF13514 AAA domain 1 201 7.7E-20 T 28-03-2018 CDW54_RS04230 07ae304469c962b85daa6cb1128d671f 906 SUPERFAMILY SSF52540 1 165 1.54E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS04230 07ae304469c962b85daa6cb1128d671f 906 SUPERFAMILY SSF52540 803 887 1.54E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS04230 07ae304469c962b85daa6cb1128d671f 906 SUPERFAMILY SSF52540 615 890 2.39E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS04230 07ae304469c962b85daa6cb1128d671f 906 Gene3D G3DSA:3.40.50.300 1 253 1.9E-11 T 28-03-2018 CDW54_RS04230 07ae304469c962b85daa6cb1128d671f 906 Gene3D G3DSA:3.40.50.300 658 896 8.9E-10 T 28-03-2018 CDW54_RS04230 07ae304469c962b85daa6cb1128d671f 906 Gene3D G3DSA:1.20.1170.10 254 632 5.4E-6 T 28-03-2018 CDW54_RS12280 d3756e8a9a3c7fe385a55681edc33abc 742 TIGRFAM TIGR01056 topB: DNA topoisomerase III 1 708 7.8E-162 T 28-03-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 CDW54_RS12280 d3756e8a9a3c7fe385a55681edc33abc 742 SMART SM00493 2 129 5.8E-28 T 28-03-2018 IPR006171 TOPRIM domain CDW54_RS12280 d3756e8a9a3c7fe385a55681edc33abc 742 Gene3D G3DSA:1.10.460.10 475 645 1.7E-27 T 28-03-2018 CDW54_RS12280 d3756e8a9a3c7fe385a55681edc33abc 742 Gene3D G3DSA:1.10.460.10 161 371 9.4E-36 T 28-03-2018 CDW54_RS12280 d3756e8a9a3c7fe385a55681edc33abc 742 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 517 531 2.0E-18 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CDW54_RS12280 d3756e8a9a3c7fe385a55681edc33abc 742 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 197 215 2.0E-18 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CDW54_RS12280 d3756e8a9a3c7fe385a55681edc33abc 742 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 103 116 2.0E-18 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CDW54_RS12280 d3756e8a9a3c7fe385a55681edc33abc 742 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 319 328 2.0E-18 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CDW54_RS12280 d3756e8a9a3c7fe385a55681edc33abc 742 SMART SM00437 277 554 1.3E-80 T 28-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 CDW54_RS12280 d3756e8a9a3c7fe385a55681edc33abc 742 Pfam PF01751 Toprim domain 4 140 3.8E-17 T 28-03-2018 IPR006171 TOPRIM domain CDW54_RS12280 d3756e8a9a3c7fe385a55681edc33abc 742 SMART SM00436 132 227 1.1E-32 T 28-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 CDW54_RS12280 d3756e8a9a3c7fe385a55681edc33abc 742 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 314 328 - T 28-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 CDW54_RS12280 d3756e8a9a3c7fe385a55681edc33abc 742 SUPERFAMILY SSF56712 2 604 2.88E-159 T 28-03-2018 IPR023405 DNA topoisomerase, type IA, core domain CDW54_RS12280 d3756e8a9a3c7fe385a55681edc33abc 742 Gene3D G3DSA:3.40.50.140 2 160 2.1E-42 T 28-03-2018 CDW54_RS12280 d3756e8a9a3c7fe385a55681edc33abc 742 Gene3D G3DSA:2.70.20.10 372 474 1.4E-18 T 28-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CDW54_RS12280 d3756e8a9a3c7fe385a55681edc33abc 742 Pfam PF01131 DNA topoisomerase 159 590 2.2E-98 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CDW54_RS12280 d3756e8a9a3c7fe385a55681edc33abc 742 Pfam PF13342 C-terminal repeat of topoisomerase 657 716 2.2E-17 T 28-03-2018 IPR025589 Topoisomerase C-terminal repeat CDW54_RS03685 14dc50f26cca24c5f69256477c40c32e 286 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 6 281 3.4E-88 T 28-03-2018 IPR003797 DegV CDW54_RS03685 14dc50f26cca24c5f69256477c40c32e 286 Gene3D G3DSA:3.40.50.10170 1 154 6.6E-44 T 28-03-2018 CDW54_RS03685 14dc50f26cca24c5f69256477c40c32e 286 Gene3D G3DSA:3.30.1180.10 155 283 4.6E-36 T 28-03-2018 CDW54_RS03685 14dc50f26cca24c5f69256477c40c32e 286 Pfam PF02645 Uncharacterised protein, DegV family COG1307 5 281 1.7E-80 T 28-03-2018 IPR003797 DegV CDW54_RS03685 14dc50f26cca24c5f69256477c40c32e 286 SUPERFAMILY SSF82549 5 281 1.83E-79 T 28-03-2018 CDW54_RS00030 fb9bbdc8b781ddf28eaa8f0aa11de58c 806 Gene3D G3DSA:3.30.70.380 709 806 6.4E-28 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CDW54_RS00030 fb9bbdc8b781ddf28eaa8f0aa11de58c 806 SUPERFAMILY SSF50249 37 196 3.92E-45 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDW54_RS00030 fb9bbdc8b781ddf28eaa8f0aa11de58c 806 SMART SM00874 411 479 1.3E-26 T 28-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CDW54_RS00030 fb9bbdc8b781ddf28eaa8f0aa11de58c 806 Gene3D G3DSA:3.30.56.10 1 54 4.1E-13 T 28-03-2018 CDW54_RS00030 fb9bbdc8b781ddf28eaa8f0aa11de58c 806 Pfam PF01588 Putative tRNA binding domain 46 150 4.4E-21 T 28-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CDW54_RS00030 fb9bbdc8b781ddf28eaa8f0aa11de58c 806 Pfam PF03483 B3/4 domain 222 394 4.3E-64 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CDW54_RS00030 fb9bbdc8b781ddf28eaa8f0aa11de58c 806 Gene3D G3DSA:3.30.930.10 497 700 5.6E-39 T 28-03-2018 CDW54_RS00030 fb9bbdc8b781ddf28eaa8f0aa11de58c 806 Gene3D G3DSA:3.30.56.10 148 191 6.9E-8 T 28-03-2018 CDW54_RS00030 fb9bbdc8b781ddf28eaa8f0aa11de58c 806 SMART SM00896 713 806 1.0E-42 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CDW54_RS00030 fb9bbdc8b781ddf28eaa8f0aa11de58c 806 SUPERFAMILY SSF46955 412 483 1.19E-19 T 28-03-2018 IPR009061 Putative DNA-binding domain CDW54_RS00030 fb9bbdc8b781ddf28eaa8f0aa11de58c 806 Pfam PF03147 Ferredoxin-fold anticodon binding domain 714 806 7.4E-31 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CDW54_RS00030 fb9bbdc8b781ddf28eaa8f0aa11de58c 806 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 806 1.1E-270 T 28-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CDW54_RS00030 fb9bbdc8b781ddf28eaa8f0aa11de58c 806 Gene3D G3DSA:2.40.50.140 55 147 8.0E-39 T 28-03-2018 CDW54_RS00030 fb9bbdc8b781ddf28eaa8f0aa11de58c 806 SUPERFAMILY SSF54991 709 806 2.22E-31 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CDW54_RS00030 fb9bbdc8b781ddf28eaa8f0aa11de58c 806 SUPERFAMILY SSF56037 209 404 4.71E-71 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CDW54_RS00030 fb9bbdc8b781ddf28eaa8f0aa11de58c 806 Gene3D G3DSA:3.50.40.10 204 404 1.4E-70 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CDW54_RS00030 fb9bbdc8b781ddf28eaa8f0aa11de58c 806 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 800 45.731 T 28-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CDW54_RS00030 fb9bbdc8b781ddf28eaa8f0aa11de58c 806 SMART SM00873 221 394 1.1E-86 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CDW54_RS00030 fb9bbdc8b781ddf28eaa8f0aa11de58c 806 SUPERFAMILY SSF55681 475 699 2.21E-51 T 28-03-2018 CDW54_RS00030 fb9bbdc8b781ddf28eaa8f0aa11de58c 806 Gene3D G3DSA:3.30.56.10 411 483 4.0E-23 T 28-03-2018 CDW54_RS00030 fb9bbdc8b781ddf28eaa8f0aa11de58c 806 Pfam PF03484 tRNA synthetase B5 domain 414 479 7.6E-19 T 28-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CDW54_RS00715 0efd07274e5cf11f2b1cb530adedb9ee 816 TIGRFAM TIGR01061 parC_Gpos: DNA topoisomerase IV, A subunit 8 752 0.0 T 28-03-2018 IPR005741 DNA topoisomerase IV subunit A, Gram-positive GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CDW54_RS00715 0efd07274e5cf11f2b1cb530adedb9ee 816 Gene3D G3DSA:2.120.10.90 499 813 7.0E-75 T 28-03-2018 CDW54_RS00715 0efd07274e5cf11f2b1cb530adedb9ee 816 SUPERFAMILY SSF101904 499 810 4.97E-77 T 28-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal CDW54_RS00715 0efd07274e5cf11f2b1cb530adedb9ee 816 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 31 470 7.5E-151 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDW54_RS00715 0efd07274e5cf11f2b1cb530adedb9ee 816 Gene3D G3DSA:3.90.199.10 33 213 2.6E-75 T 28-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 CDW54_RS00715 0efd07274e5cf11f2b1cb530adedb9ee 816 SUPERFAMILY SSF56719 30 485 6.28E-167 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CDW54_RS00715 0efd07274e5cf11f2b1cb530adedb9ee 816 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 504 527 0.12 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CDW54_RS00715 0efd07274e5cf11f2b1cb530adedb9ee 816 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 714 757 1.3E-6 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CDW54_RS00715 0efd07274e5cf11f2b1cb530adedb9ee 816 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 608 652 0.053 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CDW54_RS00715 0efd07274e5cf11f2b1cb530adedb9ee 816 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 661 702 2.0E-10 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CDW54_RS00715 0efd07274e5cf11f2b1cb530adedb9ee 816 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 549 598 4.5E-5 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CDW54_RS00715 0efd07274e5cf11f2b1cb530adedb9ee 816 Gene3D G3DSA:1.10.268.10 343 485 1.3E-48 T 28-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDW54_RS00715 0efd07274e5cf11f2b1cb530adedb9ee 816 Hamap MF_00937 DNA topoisomerase 4 subunit A [parC]. 6 809 33.969 T 28-03-2018 IPR005741 DNA topoisomerase IV subunit A, Gram-positive GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CDW54_RS00715 0efd07274e5cf11f2b1cb530adedb9ee 816 SMART SM00434 10 463 1.8E-253 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDW54_RS00715 0efd07274e5cf11f2b1cb530adedb9ee 816 Gene3D G3DSA:3.30.1360.40 235 331 2.5E-33 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CDW54_RS12060 0466d3eb1821d18f4e6498cf2fe834e5 393 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 192 392 9.5E-59 T 28-03-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 CDW54_RS12060 0466d3eb1821d18f4e6498cf2fe834e5 393 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 79 5.5E-19 T 28-03-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 CDW54_RS00235 f4bf0892fb6e34886cfa43a1f9792dfc 242 Pfam PF12836 Helix-hairpin-helix motif 179 240 4.5E-25 T 28-03-2018 CDW54_RS00235 f4bf0892fb6e34886cfa43a1f9792dfc 242 Pfam PF10531 SLBB domain 98 150 2.5E-7 T 28-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDW54_RS00235 f4bf0892fb6e34886cfa43a1f9792dfc 242 Gene3D G3DSA:1.10.150.310 199 242 5.0E-19 T 28-03-2018 CDW54_RS00235 f4bf0892fb6e34886cfa43a1f9792dfc 242 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 175 240 2.9E-24 T 28-03-2018 IPR004509 Competence protein ComEA, helix-hairpin-helix domain CDW54_RS00235 f4bf0892fb6e34886cfa43a1f9792dfc 242 SMART SM00278 219 238 0.0021 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CDW54_RS00235 f4bf0892fb6e34886cfa43a1f9792dfc 242 SMART SM00278 189 208 0.43 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CDW54_RS00235 f4bf0892fb6e34886cfa43a1f9792dfc 242 SUPERFAMILY SSF47781 173 240 3.89E-28 T 28-03-2018 IPR010994 RuvA domain 2-like CDW54_RS00235 f4bf0892fb6e34886cfa43a1f9792dfc 242 Gene3D G3DSA:1.10.150.20 139 198 3.3E-14 T 28-03-2018 CDW54_RS11510 b3f2cd34f8769c2646f497b6c3ac84ca 869 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 205 339 7.8E-14 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CDW54_RS11510 b3f2cd34f8769c2646f497b6c3ac84ca 869 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 95 147 1.2E-5 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CDW54_RS11510 b3f2cd34f8769c2646f497b6c3ac84ca 869 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 67 1.8E-5 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CDW54_RS11510 b3f2cd34f8769c2646f497b6c3ac84ca 869 SMART SM01086 771 860 9.4E-35 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CDW54_RS11510 b3f2cd34f8769c2646f497b6c3ac84ca 869 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 771 851 1.0E-24 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CDW54_RS11510 b3f2cd34f8769c2646f497b6c3ac84ca 869 SUPERFAMILY SSF81923 4 158 1.96E-33 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CDW54_RS11510 b3f2cd34f8769c2646f497b6c3ac84ca 869 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 296 308 - T 28-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 CDW54_RS11510 b3f2cd34f8769c2646f497b6c3ac84ca 869 SMART SM00382 600 744 2.3E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS11510 b3f2cd34f8769c2646f497b6c3ac84ca 869 SMART SM00382 200 344 8.3E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS11510 b3f2cd34f8769c2646f497b6c3ac84ca 869 Pfam PF07724 AAA domain (Cdc48 subfamily) 599 764 3.2E-55 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CDW54_RS11510 b3f2cd34f8769c2646f497b6c3ac84ca 869 Gene3D G3DSA:1.10.8.60 345 550 2.7E-42 T 28-03-2018 CDW54_RS11510 b3f2cd34f8769c2646f497b6c3ac84ca 869 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 678 696 1.4E-43 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CDW54_RS11510 b3f2cd34f8769c2646f497b6c3ac84ca 869 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 604 622 1.4E-43 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CDW54_RS11510 b3f2cd34f8769c2646f497b6c3ac84ca 869 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 649 667 1.4E-43 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CDW54_RS11510 b3f2cd34f8769c2646f497b6c3ac84ca 869 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 711 725 1.4E-43 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CDW54_RS11510 b3f2cd34f8769c2646f497b6c3ac84ca 869 SUPERFAMILY SSF52540 549 860 1.77E-82 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS11510 b3f2cd34f8769c2646f497b6c3ac84ca 869 Gene3D G3DSA:3.40.50.300 555 770 6.7E-53 T 28-03-2018 CDW54_RS11510 b3f2cd34f8769c2646f497b6c3ac84ca 869 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 861 0.0 T 28-03-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 CDW54_RS11510 b3f2cd34f8769c2646f497b6c3ac84ca 869 SUPERFAMILY SSF52540 161 548 1.03E-97 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS11510 b3f2cd34f8769c2646f497b6c3ac84ca 869 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 634 652 - T 28-03-2018 IPR028299 ClpA/B, conserved site 2 CDW54_RS11510 b3f2cd34f8769c2646f497b6c3ac84ca 869 Gene3D G3DSA:1.10.8.60 771 866 2.2E-24 T 28-03-2018 CDW54_RS11510 b3f2cd34f8769c2646f497b6c3ac84ca 869 Gene3D G3DSA:3.40.50.300 159 344 1.5E-27 T 28-03-2018 CDW54_RS11510 b3f2cd34f8769c2646f497b6c3ac84ca 869 Gene3D G3DSA:1.10.1780.10 1 153 1.7E-20 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CDW54_RS04525 e101eadc8addc9a88f1338f4c13a0c31 646 Gene3D G3DSA:2.60.40.810 611 646 8.7E-6 T 28-03-2018 CDW54_RS04525 e101eadc8addc9a88f1338f4c13a0c31 646 Gene3D G3DSA:2.60.40.740 496 610 1.5E-10 T 28-03-2018 CDW54_RS04525 e101eadc8addc9a88f1338f4c13a0c31 646 Gene3D G3DSA:2.60.40.740 342 485 5.9E-12 T 28-03-2018 CDW54_RS11380 d1a880a935ca6deb28e0f5caa2fced5d 313 Hamap MF_00469 UPF0176 protein YceA [yceA]. 1 265 39.59 T 28-03-2018 IPR020936 Uncharacterised protein family UPF0176 CDW54_RS11380 d1a880a935ca6deb28e0f5caa2fced5d 313 SUPERFAMILY SSF52821 86 246 9.33E-33 T 28-03-2018 IPR001763 Rhodanese-like domain CDW54_RS11380 d1a880a935ca6deb28e0f5caa2fced5d 313 SMART SM00450 113 214 1.5E-18 T 28-03-2018 IPR001763 Rhodanese-like domain CDW54_RS11380 d1a880a935ca6deb28e0f5caa2fced5d 313 Pfam PF00581 Rhodanese-like domain 114 208 1.5E-10 T 28-03-2018 IPR001763 Rhodanese-like domain CDW54_RS11380 d1a880a935ca6deb28e0f5caa2fced5d 313 Pfam PF12368 Rhodanase C-terminal 220 285 1.2E-14 T 28-03-2018 IPR022111 Rhodanase, C-terminal CDW54_RS11380 d1a880a935ca6deb28e0f5caa2fced5d 313 Gene3D G3DSA:3.40.250.10 107 220 1.0E-24 T 28-03-2018 IPR001763 Rhodanese-like domain CDW54_RS01810 3f6802be4f96a404a40fa27cabac9df4 355 SUPERFAMILY SSF51735 32 348 9.62E-53 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS01810 3f6802be4f96a404a40fa27cabac9df4 355 Pfam PF01370 NAD dependent epimerase/dehydratase family 33 276 3.8E-40 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CDW54_RS01810 3f6802be4f96a404a40fa27cabac9df4 355 Gene3D G3DSA:3.90.25.10 214 355 9.4E-21 T 28-03-2018 CDW54_RS01810 3f6802be4f96a404a40fa27cabac9df4 355 Gene3D G3DSA:3.40.50.720 26 213 2.2E-18 T 28-03-2018 CDW54_RS11700 ef9956cb825acf62e99717e599b890b7 282 Gene3D G3DSA:3.40.50.10490 83 282 9.9E-34 T 28-03-2018 CDW54_RS11700 ef9956cb825acf62e99717e599b890b7 282 Pfam PF01418 Helix-turn-helix domain, rpiR family 7 72 9.9E-19 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CDW54_RS11700 ef9956cb825acf62e99717e599b890b7 282 Gene3D G3DSA:1.10.10.10 2 77 3.8E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS11700 ef9956cb825acf62e99717e599b890b7 282 SUPERFAMILY SSF53697 95 278 9.82E-41 T 28-03-2018 CDW54_RS11700 ef9956cb825acf62e99717e599b890b7 282 SUPERFAMILY SSF46689 3 73 8.24E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDW54_RS11700 ef9956cb825acf62e99717e599b890b7 282 Pfam PF01380 SIS domain 128 256 5.0E-19 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CDW54_RS05540 1b2f122efb7dfd63ee093c383b8282f3 423 SUPERFAMILY SSF55681 117 417 8.14E-107 T 28-03-2018 CDW54_RS05540 1b2f122efb7dfd63ee093c383b8282f3 423 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 108 9.0E-31 T 28-03-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 CDW54_RS05540 1b2f122efb7dfd63ee093c383b8282f3 423 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 421 42.403 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CDW54_RS05540 1b2f122efb7dfd63ee093c383b8282f3 423 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 416 2.4E-176 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CDW54_RS05540 1b2f122efb7dfd63ee093c383b8282f3 423 PIRSF PIRSF001529 1 423 3.4E-186 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CDW54_RS05540 1b2f122efb7dfd63ee093c383b8282f3 423 SUPERFAMILY SSF46589 1 113 9.94E-31 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 CDW54_RS05540 1b2f122efb7dfd63ee093c383b8282f3 423 Gene3D G3DSA:3.30.930.10 106 423 1.9E-100 T 28-03-2018 CDW54_RS05540 1b2f122efb7dfd63ee093c383b8282f3 423 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 222 399 2.3E-34 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDW54_RS05540 1b2f122efb7dfd63ee093c383b8282f3 423 Gene3D G3DSA:1.10.287.40 2 105 1.8E-24 T 28-03-2018 CDW54_RS05540 1b2f122efb7dfd63ee093c383b8282f3 423 PRINTS PR00981 Seryl-tRNA synthetase signature 276 289 1.3E-33 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CDW54_RS05540 1b2f122efb7dfd63ee093c383b8282f3 423 PRINTS PR00981 Seryl-tRNA synthetase signature 264 276 1.3E-33 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CDW54_RS05540 1b2f122efb7dfd63ee093c383b8282f3 423 PRINTS PR00981 Seryl-tRNA synthetase signature 316 329 1.3E-33 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CDW54_RS05540 1b2f122efb7dfd63ee093c383b8282f3 423 PRINTS PR00981 Seryl-tRNA synthetase signature 351 367 1.3E-33 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CDW54_RS05540 1b2f122efb7dfd63ee093c383b8282f3 423 PRINTS PR00981 Seryl-tRNA synthetase signature 333 349 1.3E-33 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CDW54_RS02325 7f7977e1f66a475d10b3a20b5efe24ae 115 Pfam PF06156 Initiation control protein YabA 1 107 6.5E-32 T 28-03-2018 IPR010377 Initiation control protein YabA GO:0006260 CDW54_RS02325 7f7977e1f66a475d10b3a20b5efe24ae 115 PIRSF PIRSF021439 1 112 8.3E-38 T 28-03-2018 IPR010377 Initiation control protein YabA GO:0006260 CDW54_RS02325 7f7977e1f66a475d10b3a20b5efe24ae 115 Hamap MF_01159 Initiation-control protein YabA. 1 111 23.237 T 28-03-2018 IPR010377 Initiation control protein YabA GO:0006260 CDW54_RS02325 7f7977e1f66a475d10b3a20b5efe24ae 115 Gene3D G3DSA:1.20.1250.10 6 98 8.9E-4 T 28-03-2018 CDW54_RS07345 46d55af28ec71d4f3606add04d86b296 485 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 8 22 - T 28-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site CDW54_RS07345 46d55af28ec71d4f3606add04d86b296 485 SUPERFAMILY SSF51445 3 482 8.04E-160 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CDW54_RS07345 46d55af28ec71d4f3606add04d86b296 485 PRINTS PR00131 Glycosyl hydrolase family 1 signature 401 412 1.4E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS07345 46d55af28ec71d4f3606add04d86b296 485 PRINTS PR00131 Glycosyl hydrolase family 1 signature 422 439 1.4E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS07345 46d55af28ec71d4f3606add04d86b296 485 PRINTS PR00131 Glycosyl hydrolase family 1 signature 380 388 1.4E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS07345 46d55af28ec71d4f3606add04d86b296 485 PRINTS PR00131 Glycosyl hydrolase family 1 signature 447 459 1.4E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS07345 46d55af28ec71d4f3606add04d86b296 485 PRINTS PR00131 Glycosyl hydrolase family 1 signature 313 327 1.4E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS07345 46d55af28ec71d4f3606add04d86b296 485 Gene3D G3DSA:3.20.20.80 1 484 3.9E-151 T 28-03-2018 CDW54_RS07345 46d55af28ec71d4f3606add04d86b296 485 Pfam PF00232 Glycosyl hydrolase family 1 2 482 8.1E-133 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS12505 49927e0142cfb627063c7ab82789d2f1 227 Pfam PF01966 HD domain 25 125 1.8E-10 T 28-03-2018 IPR006674 HD domain CDW54_RS12505 49927e0142cfb627063c7ab82789d2f1 227 SMART SM00471 19 135 3.9E-8 T 28-03-2018 IPR003607 HD/PDEase domain CDW54_RS12505 49927e0142cfb627063c7ab82789d2f1 227 Gene3D G3DSA:1.10.3210.10 13 226 3.7E-15 T 28-03-2018 CDW54_RS12505 49927e0142cfb627063c7ab82789d2f1 227 SUPERFAMILY SSF109604 2 211 5.14E-62 T 28-03-2018 CDW54_RS05560 508c7568e04b0761afd2c7fb3cc27a44 366 SUPERFAMILY SSF52540 3 304 4.91E-91 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS05560 508c7568e04b0761afd2c7fb3cc27a44 366 SUPERFAMILY SSF81271 282 363 6.32E-36 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CDW54_RS05560 508c7568e04b0761afd2c7fb3cc27a44 366 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 366 45.933 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CDW54_RS05560 508c7568e04b0761afd2c7fb3cc27a44 366 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 366 4.1E-161 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CDW54_RS05560 508c7568e04b0761afd2c7fb3cc27a44 366 PIRSF PIRSF006641 1 366 4.9E-165 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CDW54_RS05560 508c7568e04b0761afd2c7fb3cc27a44 366 Gene3D G3DSA:3.10.20.30 266 365 8.8E-47 T 28-03-2018 IPR012675 Beta-grasp domain CDW54_RS05560 508c7568e04b0761afd2c7fb3cc27a44 366 Gene3D G3DSA:3.40.50.300 1 80 2.0E-7 T 28-03-2018 CDW54_RS05560 508c7568e04b0761afd2c7fb3cc27a44 366 Pfam PF06071 Protein of unknown function (DUF933) 282 365 9.7E-40 T 28-03-2018 IPR013029 Domain of unknown function DUF933 Reactome: R-HSA-114608 CDW54_RS05560 508c7568e04b0761afd2c7fb3cc27a44 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 1.8E-36 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CDW54_RS05560 508c7568e04b0761afd2c7fb3cc27a44 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 1.8E-36 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CDW54_RS05560 508c7568e04b0761afd2c7fb3cc27a44 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 1.8E-36 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CDW54_RS05560 508c7568e04b0761afd2c7fb3cc27a44 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 1.8E-36 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CDW54_RS05560 508c7568e04b0761afd2c7fb3cc27a44 366 Gene3D G3DSA:1.10.150.300 110 200 2.4E-30 T 28-03-2018 IPR023192 TGS-like domain Reactome: R-HSA-114608 CDW54_RS05560 508c7568e04b0761afd2c7fb3cc27a44 366 Pfam PF01926 50S ribosome-binding GTPase 5 120 3.0E-24 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CDW54_RS03580 5832760bec8f70876bea33112b16acf8 298 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 282 2.0E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS03580 5832760bec8f70876bea33112b16acf8 298 SUPERFAMILY SSF160964 11 71 1.22E-5 T 28-03-2018 CDW54_RS03580 5832760bec8f70876bea33112b16acf8 298 Gene3D G3DSA:1.10.3720.10 65 294 1.3E-42 T 28-03-2018 CDW54_RS03580 5832760bec8f70876bea33112b16acf8 298 SUPERFAMILY SSF161098 57 282 5.1E-55 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS03580 5832760bec8f70876bea33112b16acf8 298 Gene3D G3DSA:1.20.58.370 3 45 1.1E-7 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CDW54_RS04400 f6f0a911b4ce8ddfd60031e9e616a49c 900 SUPERFAMILY SSF74650 641 889 2.2E-66 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CDW54_RS04400 f6f0a911b4ce8ddfd60031e9e616a49c 900 SUPERFAMILY SSF74650 396 606 2.2E-66 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CDW54_RS04400 f6f0a911b4ce8ddfd60031e9e616a49c 900 Gene3D G3DSA:2.60.40.1180 383 541 4.1E-16 T 28-03-2018 CDW54_RS04400 f6f0a911b4ce8ddfd60031e9e616a49c 900 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 4 270 1.1E-28 T 28-03-2018 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0006013 CDW54_RS04400 f6f0a911b4ce8ddfd60031e9e616a49c 900 Gene3D G3DSA:1.20.1270.50 294 382 1.5E-21 T 28-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 CDW54_RS04400 f6f0a911b4ce8ddfd60031e9e616a49c 900 Pfam PF09261 Alpha mannosidase middle domain 298 368 5.7E-9 T 28-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 CDW54_RS04400 f6f0a911b4ce8ddfd60031e9e616a49c 900 SUPERFAMILY SSF88688 297 392 6.54E-15 T 28-03-2018 IPR028995 Glycoside hydrolase families 57/38, central domain CDW54_RS04400 f6f0a911b4ce8ddfd60031e9e616a49c 900 SMART SM00872 296 369 2.1E-19 T 28-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 CDW54_RS04400 f6f0a911b4ce8ddfd60031e9e616a49c 900 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 449 889 1.1E-36 T 28-03-2018 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0004559|GO:0006013 CDW54_RS04400 f6f0a911b4ce8ddfd60031e9e616a49c 900 SUPERFAMILY SSF88713 2 271 5.86E-63 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CDW54_RS04400 f6f0a911b4ce8ddfd60031e9e616a49c 900 Gene3D G3DSA:3.20.110.10 1 213 3.1E-46 T 28-03-2018 IPR027291 Glycoside hydrolase 38/57, N-terminal domain CDW54_RS04400 f6f0a911b4ce8ddfd60031e9e616a49c 900 Gene3D G3DSA:3.20.110.10 214 289 0.1 T 28-03-2018 IPR027291 Glycoside hydrolase 38/57, N-terminal domain CDW54_RS07650 00f62b50e69d730b31280e235b00029d 778 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS07650 00f62b50e69d730b31280e235b00029d 778 Gene3D G3DSA:3.40.50.300 1 241 1.6E-66 T 28-03-2018 CDW54_RS07650 00f62b50e69d730b31280e235b00029d 778 Pfam PF02687 FtsX-like permease family 678 770 7.1E-11 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CDW54_RS07650 00f62b50e69d730b31280e235b00029d 778 Pfam PF00005 ABC transporter 21 169 6.2E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS07650 00f62b50e69d730b31280e235b00029d 778 SUPERFAMILY SSF52540 1 224 3.33E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS07650 00f62b50e69d730b31280e235b00029d 778 SMART SM00382 30 217 8.0E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS03275 7412742a950f9bd779b7c83a12003775 211 Pfam PF00005 ABC transporter 18 163 1.3E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS03275 7412742a950f9bd779b7c83a12003775 211 SUPERFAMILY SSF52540 1 205 2.6E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS03275 7412742a950f9bd779b7c83a12003775 211 SMART SM00382 26 211 4.5E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS03275 7412742a950f9bd779b7c83a12003775 211 Gene3D G3DSA:3.40.50.300 1 209 5.6E-63 T 28-03-2018 CDW54_RS03275 7412742a950f9bd779b7c83a12003775 211 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS08255 592cb7daf923557a3437eee56df9c10f 186 Pfam PF13305 WHG domain 86 159 1.5E-8 T 28-03-2018 IPR025996 WHG domain CDW54_RS08255 592cb7daf923557a3437eee56df9c10f 186 Gene3D G3DSA:1.10.357.10 61 186 1.5E-14 T 28-03-2018 CDW54_RS08255 592cb7daf923557a3437eee56df9c10f 186 Gene3D G3DSA:1.10.10.60 1 60 3.1E-10 T 28-03-2018 CDW54_RS08255 592cb7daf923557a3437eee56df9c10f 186 SUPERFAMILY SSF46689 5 72 8.72E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDW54_RS08255 592cb7daf923557a3437eee56df9c10f 186 SUPERFAMILY SSF48498 76 185 6.45E-18 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CDW54_RS08275 834075ae582bf782d436680a4c1701fd 154 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 2 150 35.811 T 28-03-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 CDW54_RS08275 834075ae582bf782d436680a4c1701fd 154 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 116 122 - T 28-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CDW54_RS08275 834075ae582bf782d436680a4c1701fd 154 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 67 150 1.7E-30 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CDW54_RS08275 834075ae582bf782d436680a4c1701fd 154 Gene3D G3DSA:1.10.10.10 63 152 1.5E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS08275 834075ae582bf782d436680a4c1701fd 154 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 66 149 2.6E-33 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CDW54_RS08275 834075ae582bf782d436680a4c1701fd 154 SUPERFAMILY SSF46767 65 151 5.62E-30 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CDW54_RS08275 834075ae582bf782d436680a4c1701fd 154 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 2 62 1.6E-7 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CDW54_RS08275 834075ae582bf782d436680a4c1701fd 154 Gene3D G3DSA:3.30.160.70 1 62 3.1E-17 T 28-03-2018 CDW54_RS08275 834075ae582bf782d436680a4c1701fd 154 SUPERFAMILY SSF53155 3 70 2.55E-13 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CDW54_RS12260 22db05812c23a0a20382f7431065cef1 314 PIRSF PIRSF000102 2 314 1.5E-114 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CDW54_RS12260 22db05812c23a0a20382f7431065cef1 314 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 145 2.3E-45 T 28-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 CDW54_RS12260 22db05812c23a0a20382f7431065cef1 314 Hamap MF_00488 L-lactate dehydrogenase [ldh]. 5 314 45.86 T 28-03-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 CDW54_RS12260 22db05812c23a0a20382f7431065cef1 314 SUPERFAMILY SSF51735 4 145 1.84E-54 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS12260 22db05812c23a0a20382f7431065cef1 314 PRINTS PR00086 L-lactate dehydrogenase signature 7 31 3.9E-43 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CDW54_RS12260 22db05812c23a0a20382f7431065cef1 314 PRINTS PR00086 L-lactate dehydrogenase signature 32 56 3.9E-43 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CDW54_RS12260 22db05812c23a0a20382f7431065cef1 314 PRINTS PR00086 L-lactate dehydrogenase signature 143 161 3.9E-43 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CDW54_RS12260 22db05812c23a0a20382f7431065cef1 314 PRINTS PR00086 L-lactate dehydrogenase signature 173 186 3.9E-43 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CDW54_RS12260 22db05812c23a0a20382f7431065cef1 314 PRINTS PR00086 L-lactate dehydrogenase signature 119 139 3.9E-43 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CDW54_RS12260 22db05812c23a0a20382f7431065cef1 314 SUPERFAMILY SSF56327 146 313 3.75E-56 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CDW54_RS12260 22db05812c23a0a20382f7431065cef1 314 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 148 312 3.2E-36 T 28-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 CDW54_RS12260 22db05812c23a0a20382f7431065cef1 314 Gene3D G3DSA:3.40.50.720 7 146 3.9E-39 T 28-03-2018 CDW54_RS12260 22db05812c23a0a20382f7431065cef1 314 TIGRFAM TIGR01771 L-LDH-NAD: L-lactate dehydrogenase 10 307 1.5E-126 T 28-03-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 CDW54_RS12260 22db05812c23a0a20382f7431065cef1 314 ProSitePatterns PS00064 L-lactate dehydrogenase active site. 175 181 - T 28-03-2018 IPR018177 L-lactate dehydrogenase, active site GO:0004459|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 CDW54_RS12260 22db05812c23a0a20382f7431065cef1 314 Gene3D G3DSA:3.90.110.10 147 314 1.2E-50 T 28-03-2018 CDW54_RS07620 807e4bb8ea8ff8ca2a34b86831a0b691 94 Pfam PF08922 Domain of unknown function (DUF1905) 7 91 1.8E-21 T 28-03-2018 IPR015018 Protein of unknown function DUF1905 CDW54_RS07620 807e4bb8ea8ff8ca2a34b86831a0b691 94 SUPERFAMILY SSF141694 4 93 2.88E-23 T 28-03-2018 CDW54_RS07620 807e4bb8ea8ff8ca2a34b86831a0b691 94 Gene3D G3DSA:2.40.30.100 5 92 1.2E-23 T 28-03-2018 IPR015018 Protein of unknown function DUF1905 CDW54_RS01825 8114e2c7ff2472b09cee8df8fc75414e 346 SUPERFAMILY SSF53448 4 236 5.34E-46 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDW54_RS01825 8114e2c7ff2472b09cee8df8fc75414e 346 Pfam PF00535 Glycosyl transferase family 2 7 114 1.0E-28 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CDW54_RS01825 8114e2c7ff2472b09cee8df8fc75414e 346 Gene3D G3DSA:3.90.550.10 1 314 2.0E-43 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDW54_RS07910 beb57a1870a4447144f45d46ce12a44d 293 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 1 287 59.147 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CDW54_RS07910 beb57a1870a4447144f45d46ce12a44d 293 Gene3D G3DSA:3.20.20.70 1 292 9.9E-100 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDW54_RS07910 beb57a1870a4447144f45d46ce12a44d 293 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 4 285 6.9E-101 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CDW54_RS07910 beb57a1870a4447144f45d46ce12a44d 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 71 89 1.2E-31 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CDW54_RS07910 beb57a1870a4447144f45d46ce12a44d 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 128 145 1.2E-31 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CDW54_RS07910 beb57a1870a4447144f45d46ce12a44d 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 103 119 1.2E-31 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CDW54_RS07910 beb57a1870a4447144f45d46ce12a44d 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 35 56 1.2E-31 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CDW54_RS07910 beb57a1870a4447144f45d46ce12a44d 293 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 133 163 - T 28-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 CDW54_RS07910 beb57a1870a4447144f45d46ce12a44d 293 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 38 55 - T 28-03-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CDW54_RS07910 beb57a1870a4447144f45d46ce12a44d 293 PIRSF PIRSF001365 1 291 1.2E-92 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CDW54_RS07910 beb57a1870a4447144f45d46ce12a44d 293 SUPERFAMILY SSF51569 1 285 7.33E-100 T 28-03-2018 CDW54_RS07910 beb57a1870a4447144f45d46ce12a44d 293 SMART SM01130 1 289 3.7E-127 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CDW54_RS07910 beb57a1870a4447144f45d46ce12a44d 293 Pfam PF00701 Dihydrodipicolinate synthetase family 2 285 3.3E-97 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CDW54_RS09620 4c5cb755aedf10f2665ea4e19ed7d9dd 785 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 56 718 5.0E-203 T 28-03-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 CDW54_RS09620 4c5cb755aedf10f2665ea4e19ed7d9dd 785 SMART SM00955 260 590 1.3E-179 T 28-03-2018 CDW54_RS09620 4c5cb755aedf10f2665ea4e19ed7d9dd 785 SMART SM00316 636 718 2.1E-16 T 28-03-2018 IPR022967 RNA-binding domain, S1 CDW54_RS09620 4c5cb755aedf10f2665ea4e19ed7d9dd 785 SUPERFAMILY SSF50249 128 237 2.63E-7 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDW54_RS09620 4c5cb755aedf10f2665ea4e19ed7d9dd 785 ProSitePatterns PS01175 Ribonuclease II family signature. 557 581 - T 28-03-2018 IPR022966 Ribonuclease II/R, conserved site CDW54_RS09620 4c5cb755aedf10f2665ea4e19ed7d9dd 785 TIGRFAM TIGR02063 RNase_R: ribonuclease R 6 719 1.8E-267 T 28-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 CDW54_RS09620 4c5cb755aedf10f2665ea4e19ed7d9dd 785 SUPERFAMILY SSF50249 636 719 8.58E-22 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDW54_RS09620 4c5cb755aedf10f2665ea4e19ed7d9dd 785 Pfam PF00773 RNB domain 260 587 3.0E-115 T 28-03-2018 CDW54_RS09620 4c5cb755aedf10f2665ea4e19ed7d9dd 785 Hamap MF_01895 Ribonuclease R [rnr]. 25 718 56.984 T 28-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 CDW54_RS09620 4c5cb755aedf10f2665ea4e19ed7d9dd 785 Gene3D G3DSA:2.40.50.140 638 772 2.3E-22 T 28-03-2018 CDW54_RS09620 4c5cb755aedf10f2665ea4e19ed7d9dd 785 Gene3D G3DSA:2.40.50.140 74 295 0.011 T 28-03-2018 CDW54_RS09620 4c5cb755aedf10f2665ea4e19ed7d9dd 785 Pfam PF08206 Ribonuclease B OB domain 74 132 5.4E-16 T 28-03-2018 IPR013223 Ribonuclease B, N-terminal OB domain CDW54_RS09620 4c5cb755aedf10f2665ea4e19ed7d9dd 785 SUPERFAMILY SSF50249 55 137 3.74E-13 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDW54_RS09620 4c5cb755aedf10f2665ea4e19ed7d9dd 785 SUPERFAMILY SSF50249 220 635 3.37E-145 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDW54_RS09620 4c5cb755aedf10f2665ea4e19ed7d9dd 785 Pfam PF00575 S1 RNA binding domain 635 716 7.8E-15 T 28-03-2018 IPR003029 S1 domain GO:0003676 CDW54_RS08555 b7d24c7babfd8a8bf7166e82e48ad306 276 SUPERFAMILY SSF63817 91 231 8.76E-41 T 28-03-2018 IPR023365 Sortase domain CDW54_RS08555 b7d24c7babfd8a8bf7166e82e48ad306 276 Pfam PF04203 Sortase family 105 229 6.6E-24 T 28-03-2018 IPR005754 Sortase family CDW54_RS08555 b7d24c7babfd8a8bf7166e82e48ad306 276 Gene3D G3DSA:2.40.260.10 37 248 3.0E-43 T 28-03-2018 IPR023365 Sortase domain CDW54_RS08555 b7d24c7babfd8a8bf7166e82e48ad306 276 TIGRFAM TIGR01076 sortase_fam: sortase 103 235 1.8E-46 T 28-03-2018 IPR005754 Sortase family CDW54_RS08715 2d95d52d3d6e266e94717ebd58a7c21d 294 Pfam PF00781 Diacylglycerol kinase catalytic domain 3 127 3.4E-30 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CDW54_RS08715 2d95d52d3d6e266e94717ebd58a7c21d 294 SUPERFAMILY SSF111331 1 294 4.36E-73 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CDW54_RS08715 2d95d52d3d6e266e94717ebd58a7c21d 294 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 1 292 1.2E-60 T 28-03-2018 IPR005218 Diacylglycerol/lipid kinase CDW54_RS08715 2d95d52d3d6e266e94717ebd58a7c21d 294 Gene3D G3DSA:3.40.50.10330 1 131 2.5E-31 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CDW54_RS08715 2d95d52d3d6e266e94717ebd58a7c21d 294 SMART SM00046 3 131 4.5E-11 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CDW54_RS12205 216c75ee7ff554ca5c8cdcfe57023028 197 SUPERFAMILY SSF63817 45 149 1.07E-30 T 28-03-2018 IPR023365 Sortase domain CDW54_RS12205 216c75ee7ff554ca5c8cdcfe57023028 197 Gene3D G3DSA:2.40.260.10 27 165 9.4E-31 T 28-03-2018 IPR023365 Sortase domain CDW54_RS12205 216c75ee7ff554ca5c8cdcfe57023028 197 TIGRFAM TIGR01076 sortase_fam: sortase 48 154 1.2E-39 T 28-03-2018 IPR005754 Sortase family CDW54_RS12205 216c75ee7ff554ca5c8cdcfe57023028 197 Pfam PF04203 Sortase family 49 147 5.1E-16 T 28-03-2018 IPR005754 Sortase family CDW54_RS08370 76e81389c9444b9856dc600ef3a33aaa 74 SUPERFAMILY SSF47413 10 69 1.15E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDW54_RS08370 76e81389c9444b9856dc600ef3a33aaa 74 Gene3D G3DSA:1.10.260.40 6 74 5.7E-13 T 28-03-2018 CDW54_RS08370 76e81389c9444b9856dc600ef3a33aaa 74 Pfam PF01381 Helix-turn-helix 14 64 2.8E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDW54_RS08370 76e81389c9444b9856dc600ef3a33aaa 74 SMART SM00530 2 64 2.8E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDW54_RS05655 3a4ccf8b3a1d75147778b56ef4a7c95a 118 Pfam PF00825 Ribonuclease P 1 106 5.5E-31 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CDW54_RS05655 3a4ccf8b3a1d75147778b56ef4a7c95a 118 SUPERFAMILY SSF54211 1 112 3.03E-31 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CDW54_RS05655 3a4ccf8b3a1d75147778b56ef4a7c95a 118 Gene3D G3DSA:3.30.230.10 1 117 2.3E-31 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CDW54_RS05655 3a4ccf8b3a1d75147778b56ef4a7c95a 118 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 8 106 2.0E-30 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CDW54_RS05655 3a4ccf8b3a1d75147778b56ef4a7c95a 118 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 2 110 1.2E-25 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CDW54_RS05655 3a4ccf8b3a1d75147778b56ef4a7c95a 118 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 1 111 18.565 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CDW54_RS03670 914ddd52954572d41f353cbfa6811f38 438 Pfam PF07435 YycH protein 11 423 5.9E-35 T 28-03-2018 IPR009996 Regulatory protein YycH CDW54_RS08900 77fc197bc5c9165af020192d4d6c4e91 147 Pfam PF03713 Domain of unknown function (DUF305) 88 142 2.3E-11 T 28-03-2018 IPR005183 Domain of unknown function DUF305 CDW54_RS08900 77fc197bc5c9165af020192d4d6c4e91 147 Gene3D G3DSA:1.20.1260.10 18 146 3.2E-20 T 28-03-2018 IPR012347 Ferritin-related CDW54_RS00380 2c5b378bd69645cff7814b17724b02ff 424 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 329 415 1.5E-20 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CDW54_RS00380 2c5b378bd69645cff7814b17724b02ff 424 SMART SM01210 327 417 1.3E-27 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CDW54_RS00380 2c5b378bd69645cff7814b17724b02ff 424 SUPERFAMILY SSF56059 103 321 1.1E-58 T 28-03-2018 CDW54_RS00380 2c5b378bd69645cff7814b17724b02ff 424 SUPERFAMILY SSF52440 1 102 6.76E-32 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CDW54_RS00380 2c5b378bd69645cff7814b17724b02ff 424 SUPERFAMILY SSF51246 326 416 2.9E-22 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CDW54_RS00380 2c5b378bd69645cff7814b17724b02ff 424 Gene3D G3DSA:3.90.600.10 327 418 1.5E-23 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CDW54_RS00380 2c5b378bd69645cff7814b17724b02ff 424 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 417 40.207 T 28-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CDW54_RS00380 2c5b378bd69645cff7814b17724b02ff 424 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 102 294 1.5E-76 T 28-03-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CDW54_RS00380 2c5b378bd69645cff7814b17724b02ff 424 Gene3D G3DSA:3.30.470.20 190 325 1.1E-54 T 28-03-2018 CDW54_RS00380 2c5b378bd69645cff7814b17724b02ff 424 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 417 9.2E-151 T 28-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CDW54_RS00380 2c5b378bd69645cff7814b17724b02ff 424 SMART SM01209 102 294 1.9E-120 T 28-03-2018 CDW54_RS00380 2c5b378bd69645cff7814b17724b02ff 424 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 288 295 - T 28-03-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CDW54_RS00380 2c5b378bd69645cff7814b17724b02ff 424 Gene3D G3DSA:3.40.50.20 2 85 8.4E-34 T 28-03-2018 CDW54_RS00380 2c5b378bd69645cff7814b17724b02ff 424 Gene3D G3DSA:3.30.1490.20 86 188 2.5E-21 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CDW54_RS00380 2c5b378bd69645cff7814b17724b02ff 424 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 101 9.3E-32 T 28-03-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CDW54_RS06520 8a91cfb04f73cc024391e20afd25f13a 238 Gene3D G3DSA:3.30.70.1560 141 212 4.0E-19 T 28-03-2018 CDW54_RS06520 8a91cfb04f73cc024391e20afd25f13a 238 Gene3D G3DSA:3.10.290.10 1 57 6.4E-6 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDW54_RS06520 8a91cfb04f73cc024391e20afd25f13a 238 Gene3D G3DSA:3.30.70.580 58 140 5.5E-14 T 28-03-2018 CDW54_RS06520 8a91cfb04f73cc024391e20afd25f13a 238 Pfam PF00849 RNA pseudouridylate synthase 61 194 3.3E-16 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDW54_RS06520 8a91cfb04f73cc024391e20afd25f13a 238 SUPERFAMILY SSF55120 60 230 2.72E-35 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDW54_RS06520 8a91cfb04f73cc024391e20afd25f13a 238 SUPERFAMILY SSF55174 1 55 8.95E-5 T 28-03-2018 CDW54_RS06520 8a91cfb04f73cc024391e20afd25f13a 238 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 65 226 9.5E-40 T 28-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 CDW54_RS06520 8a91cfb04f73cc024391e20afd25f13a 238 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 99 113 - T 28-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 CDW54_RS07760 224b72094063863faca911068151f584 233 Gene3D G3DSA:3.40.50.300 1 224 4.6E-62 T 28-03-2018 CDW54_RS07760 224b72094063863faca911068151f584 233 Pfam PF00005 ABC transporter 24 166 9.8E-37 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS07760 224b72094063863faca911068151f584 233 SMART SM00382 32 215 7.0E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS07760 224b72094063863faca911068151f584 233 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS07760 224b72094063863faca911068151f584 233 SUPERFAMILY SSF52540 4 219 1.57E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS11475 127dfb4cddde94fcbdbcb310f86184e9 302 Pfam PF00781 Diacylglycerol kinase catalytic domain 3 129 2.3E-27 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CDW54_RS11475 127dfb4cddde94fcbdbcb310f86184e9 302 SMART SM00046 3 133 6.0E-7 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CDW54_RS11475 127dfb4cddde94fcbdbcb310f86184e9 302 SUPERFAMILY SSF111331 1 298 3.49E-64 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CDW54_RS11475 127dfb4cddde94fcbdbcb310f86184e9 302 Gene3D G3DSA:3.40.50.10330 1 133 3.9E-28 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CDW54_RS11475 127dfb4cddde94fcbdbcb310f86184e9 302 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 1 297 1.0E-45 T 28-03-2018 IPR005218 Diacylglycerol/lipid kinase CDW54_RS05690 9c414363c9f956923909708b8b04f2f9 648 Gene3D G3DSA:3.30.230.10 235 402 8.6E-66 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CDW54_RS05690 9c414363c9f956923909708b8b04f2f9 648 ProSitePatterns PS00177 DNA topoisomerase II signature. 432 440 - T 28-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDW54_RS05690 9c414363c9f956923909708b8b04f2f9 648 PRINTS PR01159 DNA gyrase subunit B signature 480 489 6.3E-75 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CDW54_RS05690 9c414363c9f956923909708b8b04f2f9 648 PRINTS PR01159 DNA gyrase subunit B signature 230 252 6.3E-75 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CDW54_RS05690 9c414363c9f956923909708b8b04f2f9 648 PRINTS PR01159 DNA gyrase subunit B signature 322 338 6.3E-75 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CDW54_RS05690 9c414363c9f956923909708b8b04f2f9 648 PRINTS PR01159 DNA gyrase subunit B signature 370 384 6.3E-75 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CDW54_RS05690 9c414363c9f956923909708b8b04f2f9 648 PRINTS PR01159 DNA gyrase subunit B signature 601 613 6.3E-75 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CDW54_RS05690 9c414363c9f956923909708b8b04f2f9 648 PRINTS PR01159 DNA gyrase subunit B signature 14 24 6.3E-75 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CDW54_RS05690 9c414363c9f956923909708b8b04f2f9 648 PRINTS PR01159 DNA gyrase subunit B signature 617 633 6.3E-75 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CDW54_RS05690 9c414363c9f956923909708b8b04f2f9 648 PRINTS PR01159 DNA gyrase subunit B signature 189 204 6.3E-75 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CDW54_RS05690 9c414363c9f956923909708b8b04f2f9 648 PRINTS PR01159 DNA gyrase subunit B signature 384 404 6.3E-75 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CDW54_RS05690 9c414363c9f956923909708b8b04f2f9 648 PRINTS PR01159 DNA gyrase subunit B signature 204 217 6.3E-75 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CDW54_RS05690 9c414363c9f956923909708b8b04f2f9 648 Gene3D G3DSA:3.40.50.670 409 645 4.8E-102 T 28-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDW54_RS05690 9c414363c9f956923909708b8b04f2f9 648 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 41 182 9.4E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS05690 9c414363c9f956923909708b8b04f2f9 648 SUPERFAMILY SSF54211 231 401 7.78E-63 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CDW54_RS05690 9c414363c9f956923909708b8b04f2f9 648 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 11 648 92.016 T 28-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CDW54_RS05690 9c414363c9f956923909708b8b04f2f9 648 SUPERFAMILY SSF55874 13 226 2.62E-71 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS05690 9c414363c9f956923909708b8b04f2f9 648 SMART SM00387 39 183 1.6E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS05690 9c414363c9f956923909708b8b04f2f9 648 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 14 648 3.2E-304 T 28-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CDW54_RS05690 9c414363c9f956923909708b8b04f2f9 648 Gene3D G3DSA:3.30.565.10 24 234 1.7E-73 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS05690 9c414363c9f956923909708b8b04f2f9 648 Pfam PF00204 DNA gyrase B 231 400 2.8E-65 T 28-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDW54_RS05690 9c414363c9f956923909708b8b04f2f9 648 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 577 637 2.4E-28 T 28-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 CDW54_RS05690 9c414363c9f956923909708b8b04f2f9 648 Pfam PF01751 Toprim domain 429 540 3.8E-18 T 28-03-2018 IPR006171 TOPRIM domain CDW54_RS05690 9c414363c9f956923909708b8b04f2f9 648 SMART SM00433 43 641 0.0 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDW54_RS05690 9c414363c9f956923909708b8b04f2f9 648 PRINTS PR00418 DNA topoisomerase II family signature 121 135 5.7E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDW54_RS05690 9c414363c9f956923909708b8b04f2f9 648 PRINTS PR00418 DNA topoisomerase II family signature 514 531 5.7E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDW54_RS05690 9c414363c9f956923909708b8b04f2f9 648 PRINTS PR00418 DNA topoisomerase II family signature 43 58 5.7E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDW54_RS05690 9c414363c9f956923909708b8b04f2f9 648 PRINTS PR00418 DNA topoisomerase II family signature 496 512 5.7E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDW54_RS05690 9c414363c9f956923909708b8b04f2f9 648 PRINTS PR00418 DNA topoisomerase II family signature 580 596 5.7E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDW54_RS05690 9c414363c9f956923909708b8b04f2f9 648 PRINTS PR00418 DNA topoisomerase II family signature 534 546 5.7E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDW54_RS05690 9c414363c9f956923909708b8b04f2f9 648 PRINTS PR00418 DNA topoisomerase II family signature 278 291 5.7E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDW54_RS05690 9c414363c9f956923909708b8b04f2f9 648 PRINTS PR00418 DNA topoisomerase II family signature 78 91 5.7E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDW54_RS05690 9c414363c9f956923909708b8b04f2f9 648 PRINTS PR00418 DNA topoisomerase II family signature 430 444 5.7E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDW54_RS05690 9c414363c9f956923909708b8b04f2f9 648 SUPERFAMILY SSF56719 404 639 2.88E-87 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CDW54_RS00760 5a02cad1f904aa45d0504e03ec1d5f87 458 Hamap MF_01037 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO [trmFO]. 21 449 36.22 T 28-03-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 CDW54_RS00760 5a02cad1f904aa45d0504e03ec1d5f87 458 SUPERFAMILY SSF51905 23 381 2.02E-29 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS00760 5a02cad1f904aa45d0504e03ec1d5f87 458 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 352 375 - T 28-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 CDW54_RS00760 5a02cad1f904aa45d0504e03ec1d5f87 458 Gene3D G3DSA:3.50.50.60 19 396 6.4E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS00760 5a02cad1f904aa45d0504e03ec1d5f87 458 Pfam PF01134 Glucose inhibited division protein A 21 382 8.8E-115 T 28-03-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 CDW54_RS00760 5a02cad1f904aa45d0504e03ec1d5f87 458 TIGRFAM TIGR00137 gid_trmFO: tRNA:m(5)U-54 methyltransferase 20 448 8.9E-223 T 28-03-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 CDW54_RS02210 8698f5c2e8abc9c506071021da4e8d03 213 Gene3D G3DSA:3.40.470.10 3 213 5.9E-37 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CDW54_RS02210 8698f5c2e8abc9c506071021da4e8d03 213 SMART SM00987 25 204 1.0E-18 T 28-03-2018 CDW54_RS02210 8698f5c2e8abc9c506071021da4e8d03 213 SMART SM00986 25 204 1.0E-18 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CDW54_RS02210 8698f5c2e8abc9c506071021da4e8d03 213 SUPERFAMILY SSF52141 18 211 3.2E-40 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CDW54_RS02210 8698f5c2e8abc9c506071021da4e8d03 213 Pfam PF03167 Uracil DNA glycosylase superfamily 26 192 1.7E-35 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CDW54_RS11010 4c2d7ca9b98be4419d435fc7af309a3f 664 SMART SM00487 14 429 4.5E-25 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CDW54_RS11010 4c2d7ca9b98be4419d435fc7af309a3f 664 Gene3D G3DSA:4.10.860.10 603 663 1.5E-12 T 28-03-2018 IPR001943 UVR domain GO:0005515 CDW54_RS11010 4c2d7ca9b98be4419d435fc7af309a3f 664 Gene3D G3DSA:3.40.50.300 419 593 2.9E-32 T 28-03-2018 CDW54_RS11010 4c2d7ca9b98be4419d435fc7af309a3f 664 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 9 661 0.0 T 28-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 CDW54_RS11010 4c2d7ca9b98be4419d435fc7af309a3f 664 Pfam PF12344 Ultra-violet resistance protein B 556 598 3.3E-23 T 28-03-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain CDW54_RS11010 4c2d7ca9b98be4419d435fc7af309a3f 664 Hamap MF_00204 UvrABC system protein B [uvrB]. 8 663 44.304 T 28-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 CDW54_RS11010 4c2d7ca9b98be4419d435fc7af309a3f 664 SMART SM00490 464 550 1.3E-21 T 28-03-2018 IPR001650 Helicase, C-terminal CDW54_RS11010 4c2d7ca9b98be4419d435fc7af309a3f 664 Pfam PF02151 UvrB/uvrC motif 631 662 7.8E-9 T 28-03-2018 IPR001943 UVR domain GO:0005515 CDW54_RS11010 4c2d7ca9b98be4419d435fc7af309a3f 664 Gene3D G3DSA:3.40.50.300 15 416 9.9E-32 T 28-03-2018 CDW54_RS11010 4c2d7ca9b98be4419d435fc7af309a3f 664 Pfam PF04851 Type III restriction enzyme, res subunit 18 143 1.5E-10 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CDW54_RS11010 4c2d7ca9b98be4419d435fc7af309a3f 664 SUPERFAMILY SSF52540 10 419 7.92E-140 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS11010 4c2d7ca9b98be4419d435fc7af309a3f 664 SUPERFAMILY SSF46600 620 662 2.09E-9 T 28-03-2018 IPR001943 UVR domain GO:0005515 CDW54_RS11010 4c2d7ca9b98be4419d435fc7af309a3f 664 SUPERFAMILY SSF52540 38 72 5.66E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS11010 4c2d7ca9b98be4419d435fc7af309a3f 664 SUPERFAMILY SSF52540 461 590 5.66E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS11010 4c2d7ca9b98be4419d435fc7af309a3f 664 Pfam PF00271 Helicase conserved C-terminal domain 442 549 4.0E-18 T 28-03-2018 IPR001650 Helicase, C-terminal CDW54_RS10095 fe5d46539a336207c9a60634afe128d6 376 Gene3D G3DSA:3.40.50.2000 203 348 7.0E-38 T 28-03-2018 CDW54_RS10095 fe5d46539a336207c9a60634afe128d6 376 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 22 361 1.5E-121 T 28-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 CDW54_RS10095 fe5d46539a336207c9a60634afe128d6 376 Gene3D G3DSA:3.40.50.2000 2 202 7.7E-80 T 28-03-2018 CDW54_RS10095 fe5d46539a336207c9a60634afe128d6 376 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 2 364 3.2E-164 T 28-03-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 CDW54_RS10095 fe5d46539a336207c9a60634afe128d6 376 SUPERFAMILY SSF53756 1 365 5.76E-139 T 28-03-2018 CDW54_RS06875 3d62b12d5fad6ae5edeb1365b7337c72 165 SUPERFAMILY SSF55729 4 159 5.16E-26 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDW54_RS06875 3d62b12d5fad6ae5edeb1365b7337c72 165 Gene3D G3DSA:3.40.630.30 2 164 4.6E-25 T 28-03-2018 CDW54_RS06875 3d62b12d5fad6ae5edeb1365b7337c72 165 Pfam PF13673 Acetyltransferase (GNAT) domain 44 145 3.8E-17 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CDW54_RS07640 f8c176abf63a273b898bd74a01b815bf 491 Gene3D G3DSA:3.40.1670.10 324 479 6.1E-32 T 28-03-2018 CDW54_RS07640 f8c176abf63a273b898bd74a01b815bf 491 SUPERFAMILY SSF143968 326 482 1.44E-32 T 28-03-2018 CDW54_RS07640 f8c176abf63a273b898bd74a01b815bf 491 SUPERFAMILY SSF50475 7 322 3.14E-58 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CDW54_RS07640 f8c176abf63a273b898bd74a01b815bf 491 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 20 434 7.7E-96 T 28-03-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 CDW54_RS04180 07fa51c893de721b24104586d0b69be3 309 Gene3D G3DSA:3.40.50.300 126 307 1.6E-23 T 28-03-2018 CDW54_RS04180 07fa51c893de721b24104586d0b69be3 309 Gene3D G3DSA:3.30.450.90 1 109 3.8E-20 T 28-03-2018 CDW54_RS04180 07fa51c893de721b24104586d0b69be3 309 SMART SM00382 133 268 0.0012 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS04180 07fa51c893de721b24104586d0b69be3 309 Pfam PF00437 Type II/IV secretion system protein 10 267 7.1E-44 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CDW54_RS04180 07fa51c893de721b24104586d0b69be3 309 SUPERFAMILY SSF52540 4 278 2.22E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS04180 07fa51c893de721b24104586d0b69be3 309 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 197 211 - T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CDW54_RS04300 e1f93096a9366d769adb3d90be6b4761 292 Pfam PF00326 Prolyl oligopeptidase family 92 185 9.0E-6 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CDW54_RS04300 e1f93096a9366d769adb3d90be6b4761 292 SUPERFAMILY SSF53474 42 292 1.33E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CDW54_RS04300 e1f93096a9366d769adb3d90be6b4761 292 Gene3D G3DSA:3.40.50.1820 37 292 1.3E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CDW54_RS00970 ec0aef7569c36d5a109adbfc7fa4841b 238 SUPERFAMILY SSF55120 46 235 8.22E-48 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDW54_RS00970 ec0aef7569c36d5a109adbfc7fa4841b 238 Gene3D G3DSA:3.10.290.10 1 69 3.2E-18 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDW54_RS00970 ec0aef7569c36d5a109adbfc7fa4841b 238 Gene3D G3DSA:3.30.2350.10 70 238 3.2E-43 T 28-03-2018 CDW54_RS00970 ec0aef7569c36d5a109adbfc7fa4841b 238 SMART SM00363 2 59 1.7E-13 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDW54_RS00970 ec0aef7569c36d5a109adbfc7fa4841b 238 SUPERFAMILY SSF55174 2 67 5.1E-15 T 28-03-2018 CDW54_RS00970 ec0aef7569c36d5a109adbfc7fa4841b 238 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 226 6.6E-51 T 28-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 CDW54_RS00970 ec0aef7569c36d5a109adbfc7fa4841b 238 Pfam PF01479 S4 domain 2 48 2.4E-12 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDW54_RS00970 ec0aef7569c36d5a109adbfc7fa4841b 238 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 99 113 - T 28-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 CDW54_RS00970 ec0aef7569c36d5a109adbfc7fa4841b 238 Pfam PF00849 RNA pseudouridylate synthase 62 196 4.8E-24 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDW54_RS00835 6ac88e7576c6b011a9f0600c06ce95d8 280 Pfam PF02645 Uncharacterised protein, DegV family COG1307 4 278 1.4E-88 T 28-03-2018 IPR003797 DegV CDW54_RS00835 6ac88e7576c6b011a9f0600c06ce95d8 280 Gene3D G3DSA:2.20.28.50 29 54 1.6E-15 T 28-03-2018 CDW54_RS00835 6ac88e7576c6b011a9f0600c06ce95d8 280 Gene3D G3DSA:3.30.1180.10 153 280 9.1E-31 T 28-03-2018 CDW54_RS00835 6ac88e7576c6b011a9f0600c06ce95d8 280 SUPERFAMILY SSF82549 1 279 1.62E-88 T 28-03-2018 CDW54_RS00835 6ac88e7576c6b011a9f0600c06ce95d8 280 Gene3D G3DSA:3.40.50.10440 55 150 1.4E-33 T 28-03-2018 CDW54_RS00835 6ac88e7576c6b011a9f0600c06ce95d8 280 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 4 278 1.2E-95 T 28-03-2018 IPR003797 DegV CDW54_RS06330 cefd8fba478da61ffc3b4277161e8d58 203 SUPERFAMILY SSF55174 3 200 4.19E-66 T 28-03-2018 CDW54_RS06330 cefd8fba478da61ffc3b4277161e8d58 203 Gene3D G3DSA:1.10.1050.10 143 201 1.3E-11 T 28-03-2018 CDW54_RS06330 cefd8fba478da61ffc3b4277161e8d58 203 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 201 35.247 T 28-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CDW54_RS06330 cefd8fba478da61ffc3b4277161e8d58 203 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 92 1.9E-27 T 28-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CDW54_RS06330 cefd8fba478da61ffc3b4277161e8d58 203 ProSitePatterns PS00632 Ribosomal protein S4 signature. 91 115 - T 28-03-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS06330 cefd8fba478da61ffc3b4277161e8d58 203 SMART SM01390 3 92 9.8E-45 T 28-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CDW54_RS06330 cefd8fba478da61ffc3b4277161e8d58 203 SMART SM00363 93 157 2.6E-20 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDW54_RS06330 cefd8fba478da61ffc3b4277161e8d58 203 Pfam PF01479 S4 domain 93 140 1.1E-21 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDW54_RS06330 cefd8fba478da61ffc3b4277161e8d58 203 Gene3D G3DSA:1.10.1050.10 1 98 2.3E-39 T 28-03-2018 CDW54_RS06330 cefd8fba478da61ffc3b4277161e8d58 203 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 200 4.4E-79 T 28-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CDW54_RS06330 cefd8fba478da61ffc3b4277161e8d58 203 Gene3D G3DSA:3.10.290.10 99 142 1.7E-18 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDW54_RS12285 9c186fd0c1ff15dad2196f0a37e5a030 136 SUPERFAMILY SSF54593 3 136 1.32E-29 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDW54_RS12285 9c186fd0c1ff15dad2196f0a37e5a030 136 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 4 133 3.6E-13 T 28-03-2018 IPR028973 PhnB-like CDW54_RS12285 9c186fd0c1ff15dad2196f0a37e5a030 136 Gene3D G3DSA:3.10.180.10 1 136 1.1E-21 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDW54_RS07465 2308ecf7c5e787223b12d5843bf89c8f 106 SUPERFAMILY SSF117782 1 105 2.09E-37 T 28-03-2018 IPR002765 Uncharacterised protein family UPF0145 CDW54_RS07465 2308ecf7c5e787223b12d5843bf89c8f 106 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 1 105 23.795 T 28-03-2018 IPR002765 Uncharacterised protein family UPF0145 CDW54_RS07465 2308ecf7c5e787223b12d5843bf89c8f 106 Gene3D G3DSA:3.30.110.70 1 104 8.7E-35 T 28-03-2018 IPR035439 Uncharacterised protein family UPF0145/C2CD5 Reactome: R-HSA-1445148 CDW54_RS07465 2308ecf7c5e787223b12d5843bf89c8f 106 Pfam PF01906 Putative heavy-metal-binding 1 104 1.8E-38 T 28-03-2018 IPR002765 Uncharacterised protein family UPF0145 CDW54_RS02460 2075401e2f36b886aba77fbe8a359c3c 289 PIRSF PIRSF001359 1 289 5.1E-111 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CDW54_RS02460 2075401e2f36b886aba77fbe8a359c3c 289 SUPERFAMILY SSF51569 1 289 1.34E-96 T 28-03-2018 CDW54_RS02460 2075401e2f36b886aba77fbe8a359c3c 289 Pfam PF01116 Fructose-bisphosphate aldolase class-II 7 288 9.8E-96 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CDW54_RS02460 2075401e2f36b886aba77fbe8a359c3c 289 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 133 144 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CDW54_RS02460 2075401e2f36b886aba77fbe8a359c3c 289 Gene3D G3DSA:3.20.20.70 1 289 1.5E-97 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDW54_RS02460 2075401e2f36b886aba77fbe8a359c3c 289 TIGRFAM TIGR01859 fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II 4 289 4.9E-118 T 28-03-2018 IPR011289 Fructose-1,6-bisphosphate aldolase, class 2 GO:0004332|GO:0006096|GO:0008270|GO:0030388 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 CDW54_RS02460 2075401e2f36b886aba77fbe8a359c3c 289 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 2 289 1.7E-92 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CDW54_RS02460 2075401e2f36b886aba77fbe8a359c3c 289 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 74 87 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CDW54_RS05265 e05c8473e7e4759f748e163c89125ced 155 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 28 44 3.1E-13 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CDW54_RS05265 e05c8473e7e4759f748e163c89125ced 155 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 125 143 3.1E-13 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CDW54_RS05265 e05c8473e7e4759f748e163c89125ced 155 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 52 68 3.1E-13 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CDW54_RS05265 e05c8473e7e4759f748e163c89125ced 155 Gene3D G3DSA:1.20.1260.10 2 154 6.0E-45 T 28-03-2018 IPR012347 Ferritin-related CDW54_RS05265 e05c8473e7e4759f748e163c89125ced 155 PIRSF PIRSF005900 1 152 1.3E-44 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CDW54_RS05265 e05c8473e7e4759f748e163c89125ced 155 SUPERFAMILY SSF47240 4 148 1.12E-43 T 28-03-2018 IPR009078 Ferritin-like superfamily CDW54_RS05265 e05c8473e7e4759f748e163c89125ced 155 ProSitePatterns PS00818 Dps protein family signature 1. 28 44 - T 28-03-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 CDW54_RS05265 e05c8473e7e4759f748e163c89125ced 155 Pfam PF00210 Ferritin-like domain 8 151 7.8E-32 T 28-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 CDW54_RS06485 e060a8a809104a232e7c6419e954cbd6 708 Gene3D G3DSA:2.40.50.140 619 702 9.4E-25 T 28-03-2018 CDW54_RS06485 e060a8a809104a232e7c6419e954cbd6 708 SUPERFAMILY SSF54791 559 644 1.14E-22 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CDW54_RS06485 e060a8a809104a232e7c6419e954cbd6 708 Pfam PF00013 KH domain 562 618 3.5E-8 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CDW54_RS06485 e060a8a809104a232e7c6419e954cbd6 708 SMART SM00322 556 621 2.4E-10 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CDW54_RS06485 e060a8a809104a232e7c6419e954cbd6 708 Gene3D G3DSA:1.10.10.400 249 315 2.6E-16 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CDW54_RS06485 e060a8a809104a232e7c6419e954cbd6 708 Gene3D G3DSA:3.30.230.70 316 553 2.2E-60 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CDW54_RS06485 e060a8a809104a232e7c6419e954cbd6 708 Gene3D G3DSA:3.30.1370.10 554 618 1.0E-12 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CDW54_RS06485 e060a8a809104a232e7c6419e954cbd6 708 SUPERFAMILY SSF54211 7 143 1.01E-46 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CDW54_RS06485 e060a8a809104a232e7c6419e954cbd6 708 PIRSF PIRSF005499 1 708 2.2E-291 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CDW54_RS06485 e060a8a809104a232e7c6419e954cbd6 708 Pfam PF01138 3' exoribonuclease family, domain 1 14 143 1.2E-20 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CDW54_RS06485 e060a8a809104a232e7c6419e954cbd6 708 Pfam PF01138 3' exoribonuclease family, domain 1 327 460 4.7E-18 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CDW54_RS06485 e060a8a809104a232e7c6419e954cbd6 708 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 3 697 30.393 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CDW54_RS06485 e060a8a809104a232e7c6419e954cbd6 708 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 11 695 0.0 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CDW54_RS06485 e060a8a809104a232e7c6419e954cbd6 708 Pfam PF03725 3' exoribonuclease family, domain 2 146 209 5.4E-12 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CDW54_RS06485 e060a8a809104a232e7c6419e954cbd6 708 Pfam PF03725 3' exoribonuclease family, domain 2 463 532 1.1E-8 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CDW54_RS06485 e060a8a809104a232e7c6419e954cbd6 708 SMART SM00316 624 694 1.5E-24 T 28-03-2018 IPR022967 RNA-binding domain, S1 CDW54_RS06485 e060a8a809104a232e7c6419e954cbd6 708 Pfam PF00575 S1 RNA binding domain 623 694 8.0E-20 T 28-03-2018 IPR003029 S1 domain GO:0003676 CDW54_RS06485 e060a8a809104a232e7c6419e954cbd6 708 Gene3D G3DSA:3.30.230.70 12 248 1.3E-55 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CDW54_RS06485 e060a8a809104a232e7c6419e954cbd6 708 SUPERFAMILY SSF55666 144 234 7.2E-28 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CDW54_RS06485 e060a8a809104a232e7c6419e954cbd6 708 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 241 324 7.1E-11 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CDW54_RS06485 e060a8a809104a232e7c6419e954cbd6 708 SUPERFAMILY SSF54211 297 492 4.66E-46 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CDW54_RS06485 e060a8a809104a232e7c6419e954cbd6 708 SUPERFAMILY SSF50249 624 705 2.39E-21 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDW54_RS06485 e060a8a809104a232e7c6419e954cbd6 708 SUPERFAMILY SSF55666 454 553 8.55E-30 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CDW54_RS06485 e060a8a809104a232e7c6419e954cbd6 708 SUPERFAMILY SSF46915 237 325 3.92E-14 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CDW54_RS04010 56b3de683304c2538dd3b6c7858c0913 1042 Pfam PF13558 Putative exonuclease SbcCD, C subunit 921 999 4.0E-14 T 28-03-2018 CDW54_RS04010 56b3de683304c2538dd3b6c7858c0913 1042 Gene3D G3DSA:1.10.287.620 607 749 2.0E-5 T 28-03-2018 CDW54_RS04010 56b3de683304c2538dd3b6c7858c0913 1042 Gene3D G3DSA:3.40.50.300 750 1036 6.4E-9 T 28-03-2018 CDW54_RS04010 56b3de683304c2538dd3b6c7858c0913 1042 Pfam PF13476 AAA domain 5 266 2.9E-31 T 28-03-2018 CDW54_RS04010 56b3de683304c2538dd3b6c7858c0913 1042 Gene3D G3DSA:3.40.50.300 1 195 1.2E-27 T 28-03-2018 CDW54_RS04010 56b3de683304c2538dd3b6c7858c0913 1042 Gene3D G3DSA:1.20.120.330 427 605 4.8E-4 T 28-03-2018 CDW54_RS04010 56b3de683304c2538dd3b6c7858c0913 1042 SUPERFAMILY SSF52540 1 229 4.4E-24 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS04010 56b3de683304c2538dd3b6c7858c0913 1042 SUPERFAMILY SSF52540 933 1025 4.4E-24 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS10810 7be32c3ac229238a2679ac1a0b24cb33 363 Pfam PF00266 Aminotransferase class-V 29 298 8.9E-26 T 28-03-2018 IPR000192 Aminotransferase class V domain CDW54_RS10810 7be32c3ac229238a2679ac1a0b24cb33 363 Hamap MF_01376 2-aminoethylphosphonate--pyruvate transaminase [phnW]. 1 363 165.294 T 28-03-2018 IPR012703 2-aminoethylphosphonate--pyruvate transaminase GO:0019700|GO:0047304 KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832 CDW54_RS10810 7be32c3ac229238a2679ac1a0b24cb33 363 TIGRFAM TIGR02326 transamin_PhnW: 2-aminoethylphosphonate--pyruvate transaminase 2 358 2.0E-154 T 28-03-2018 IPR012703 2-aminoethylphosphonate--pyruvate transaminase GO:0019700|GO:0047304 KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832 CDW54_RS10810 7be32c3ac229238a2679ac1a0b24cb33 363 TIGRFAM TIGR03301 PhnW-AepZ: 2-aminoethylphosphonate aminotransferase 4 357 2.9E-136 T 28-03-2018 IPR012703 2-aminoethylphosphonate--pyruvate transaminase GO:0019700|GO:0047304 KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832 CDW54_RS10810 7be32c3ac229238a2679ac1a0b24cb33 363 PIRSF PIRSF000524 1 361 5.1E-61 T 28-03-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661 CDW54_RS10810 7be32c3ac229238a2679ac1a0b24cb33 363 SUPERFAMILY SSF53383 2 358 4.52E-82 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDW54_RS10810 7be32c3ac229238a2679ac1a0b24cb33 363 Gene3D G3DSA:3.40.640.10 13 251 1.3E-27 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDW54_RS10810 7be32c3ac229238a2679ac1a0b24cb33 363 Gene3D G3DSA:3.90.1150.10 252 360 3.1E-26 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDW54_RS06005 f9810308c1357c9d24727dd884a922b1 166 SUPERFAMILY SSF54768 8 76 2.62E-25 T 28-03-2018 CDW54_RS06005 f9810308c1357c9d24727dd884a922b1 166 ProSitePatterns PS00585 Ribosomal protein S5 signature. 28 60 - T 28-03-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site CDW54_RS06005 f9810308c1357c9d24727dd884a922b1 166 SUPERFAMILY SSF54211 79 159 1.24E-24 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CDW54_RS06005 f9810308c1357c9d24727dd884a922b1 166 Gene3D G3DSA:3.30.230.10 76 166 3.6E-30 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CDW54_RS06005 f9810308c1357c9d24727dd884a922b1 166 Gene3D G3DSA:3.30.160.20 10 72 7.7E-32 T 28-03-2018 CDW54_RS06005 f9810308c1357c9d24727dd884a922b1 166 Pfam PF03719 Ribosomal protein S5, C-terminal domain 87 157 4.3E-28 T 28-03-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 CDW54_RS06005 f9810308c1357c9d24727dd884a922b1 166 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 163 35.565 T 28-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 CDW54_RS06005 f9810308c1357c9d24727dd884a922b1 166 Pfam PF00333 Ribosomal protein S5, N-terminal domain 11 75 4.4E-33 T 28-03-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 CDW54_RS06005 f9810308c1357c9d24727dd884a922b1 166 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 10 163 6.0E-69 T 28-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 CDW54_RS07925 cefe494f75f71f00ff777af1f23b82fc 333 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 7 116 7.7E-28 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CDW54_RS07925 cefe494f75f71f00ff777af1f23b82fc 333 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 3 325 32.97 T 28-03-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CDW54_RS07925 cefe494f75f71f00ff777af1f23b82fc 333 SUPERFAMILY SSF51735 4 154 1.25E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS07925 cefe494f75f71f00ff777af1f23b82fc 333 Gene3D G3DSA:3.40.50.720 1 138 1.5E-30 T 28-03-2018 CDW54_RS07925 cefe494f75f71f00ff777af1f23b82fc 333 SMART SM00859 5 120 4.2E-28 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CDW54_RS07925 cefe494f75f71f00ff777af1f23b82fc 333 SUPERFAMILY SSF55347 127 312 5.76E-63 T 28-03-2018 CDW54_RS07925 cefe494f75f71f00ff777af1f23b82fc 333 PIRSF PIRSF000148 3 329 1.9E-117 T 28-03-2018 CDW54_RS07925 cefe494f75f71f00ff777af1f23b82fc 333 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 137 311 5.0E-43 T 28-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CDW54_RS07925 cefe494f75f71f00ff777af1f23b82fc 333 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 7 326 2.7E-118 T 28-03-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CDW54_RS07925 cefe494f75f71f00ff777af1f23b82fc 333 Gene3D G3DSA:3.30.360.10 139 308 4.1E-58 T 28-03-2018 CDW54_RS08855 b3eed8a69b0bf4178be5fa09307c32f8 892 Pfam PF00122 E1-E2 ATPase 140 332 8.4E-47 T 28-03-2018 CDW54_RS08855 b3eed8a69b0bf4178be5fa09307c32f8 892 PRINTS PR01836 Magnesium-transporting ATPase signature 265 281 2.1E-69 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CDW54_RS08855 b3eed8a69b0bf4178be5fa09307c32f8 892 PRINTS PR01836 Magnesium-transporting ATPase signature 386 399 2.1E-69 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CDW54_RS08855 b3eed8a69b0bf4178be5fa09307c32f8 892 PRINTS PR01836 Magnesium-transporting ATPase signature 727 740 2.1E-69 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CDW54_RS08855 b3eed8a69b0bf4178be5fa09307c32f8 892 PRINTS PR01836 Magnesium-transporting ATPase signature 747 763 2.1E-69 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CDW54_RS08855 b3eed8a69b0bf4178be5fa09307c32f8 892 PRINTS PR01836 Magnesium-transporting ATPase signature 695 706 2.1E-69 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CDW54_RS08855 b3eed8a69b0bf4178be5fa09307c32f8 892 PRINTS PR01836 Magnesium-transporting ATPase signature 795 816 2.1E-69 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CDW54_RS08855 b3eed8a69b0bf4178be5fa09307c32f8 892 PRINTS PR01836 Magnesium-transporting ATPase signature 845 866 2.1E-69 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CDW54_RS08855 b3eed8a69b0bf4178be5fa09307c32f8 892 PRINTS PR01836 Magnesium-transporting ATPase signature 677 692 2.1E-69 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CDW54_RS08855 b3eed8a69b0bf4178be5fa09307c32f8 892 PRINTS PR01836 Magnesium-transporting ATPase signature 282 301 2.1E-69 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CDW54_RS08855 b3eed8a69b0bf4178be5fa09307c32f8 892 Pfam PF00690 Cation transporter/ATPase, N-terminus 27 91 7.5E-14 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CDW54_RS08855 b3eed8a69b0bf4178be5fa09307c32f8 892 SUPERFAMILY SSF81653 143 251 1.83E-29 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CDW54_RS08855 b3eed8a69b0bf4178be5fa09307c32f8 892 SMART SM00831 23 96 3.9E-9 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CDW54_RS08855 b3eed8a69b0bf4178be5fa09307c32f8 892 SUPERFAMILY SSF81665 27 143 5.49E-94 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CDW54_RS08855 b3eed8a69b0bf4178be5fa09307c32f8 892 SUPERFAMILY SSF81665 668 888 5.49E-94 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CDW54_RS08855 b3eed8a69b0bf4178be5fa09307c32f8 892 SUPERFAMILY SSF81665 253 346 5.49E-94 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CDW54_RS08855 b3eed8a69b0bf4178be5fa09307c32f8 892 Pfam PF00702 haloacid dehalogenase-like hydrolase 348 633 5.4E-16 T 28-03-2018 CDW54_RS08855 b3eed8a69b0bf4178be5fa09307c32f8 892 Pfam PF00689 Cation transporting ATPase, C-terminus 702 883 6.3E-13 T 28-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 CDW54_RS08855 b3eed8a69b0bf4178be5fa09307c32f8 892 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 112 370 1.8E-34 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDW54_RS08855 b3eed8a69b0bf4178be5fa09307c32f8 892 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 586 708 6.6E-27 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDW54_RS08855 b3eed8a69b0bf4178be5fa09307c32f8 892 SUPERFAMILY SSF81660 319 521 4.97E-39 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CDW54_RS08855 b3eed8a69b0bf4178be5fa09307c32f8 892 Gene3D G3DSA:1.20.1110.10 530 887 3.5E-51 T 28-03-2018 CDW54_RS08855 b3eed8a69b0bf4178be5fa09307c32f8 892 TIGRFAM TIGR01524 ATPase-IIIB_Mg: magnesium-translocating P-type ATPase 15 890 0.0 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CDW54_RS08855 b3eed8a69b0bf4178be5fa09307c32f8 892 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 354 360 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CDW54_RS08855 b3eed8a69b0bf4178be5fa09307c32f8 892 Gene3D G3DSA:2.70.150.10 32 254 4.3E-42 T 28-03-2018 CDW54_RS08855 b3eed8a69b0bf4178be5fa09307c32f8 892 SUPERFAMILY SSF56784 512 659 1.81E-37 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS08855 b3eed8a69b0bf4178be5fa09307c32f8 892 Gene3D G3DSA:3.40.1110.10 310 526 9.6E-36 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CDW54_RS02420 58c2c8579b6120f112f825c66a3803d9 149 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 6 148 8.0E-33 T 28-03-2018 IPR002178 PTS EIIA type-2 domain CDW54_RS02420 58c2c8579b6120f112f825c66a3803d9 149 SUPERFAMILY SSF55804 1 148 3.14E-34 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CDW54_RS02420 58c2c8579b6120f112f825c66a3803d9 149 Gene3D G3DSA:3.40.930.10 1 149 1.7E-33 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CDW54_RS02420 58c2c8579b6120f112f825c66a3803d9 149 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 7 132 1.1E-30 T 28-03-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 CDW54_RS05450 aa3b97e8da8dbd55cadc80b7621a6226 830 Gene3D G3DSA:1.10.1780.10 1 76 1.8E-16 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CDW54_RS05450 aa3b97e8da8dbd55cadc80b7621a6226 830 Gene3D G3DSA:1.10.8.60 728 828 2.1E-24 T 28-03-2018 CDW54_RS05450 aa3b97e8da8dbd55cadc80b7621a6226 830 SUPERFAMILY SSF52540 500 796 7.16E-78 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS05450 aa3b97e8da8dbd55cadc80b7621a6226 830 SUPERFAMILY SSF52540 175 499 2.39E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS05450 aa3b97e8da8dbd55cadc80b7621a6226 830 Pfam PF02151 UvrB/uvrC motif 433 466 5.7E-6 T 28-03-2018 IPR001943 UVR domain GO:0005515 CDW54_RS05450 aa3b97e8da8dbd55cadc80b7621a6226 830 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 309 321 - T 28-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 CDW54_RS05450 aa3b97e8da8dbd55cadc80b7621a6226 830 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 728 808 6.2E-25 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CDW54_RS05450 aa3b97e8da8dbd55cadc80b7621a6226 830 SMART SM01086 728 817 3.4E-35 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CDW54_RS05450 aa3b97e8da8dbd55cadc80b7621a6226 830 Gene3D G3DSA:1.10.8.60 359 501 1.2E-37 T 28-03-2018 CDW54_RS05450 aa3b97e8da8dbd55cadc80b7621a6226 830 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 585 603 - T 28-03-2018 IPR028299 ClpA/B, conserved site 2 CDW54_RS05450 aa3b97e8da8dbd55cadc80b7621a6226 830 Gene3D G3DSA:1.10.1780.10 77 207 1.2E-20 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CDW54_RS05450 aa3b97e8da8dbd55cadc80b7621a6226 830 SUPERFAMILY SSF81923 4 145 4.61E-26 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CDW54_RS05450 aa3b97e8da8dbd55cadc80b7621a6226 830 Pfam PF07724 AAA domain (Cdc48 subfamily) 550 721 2.3E-55 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CDW54_RS05450 aa3b97e8da8dbd55cadc80b7621a6226 830 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 629 647 2.9E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CDW54_RS05450 aa3b97e8da8dbd55cadc80b7621a6226 830 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 600 618 2.9E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CDW54_RS05450 aa3b97e8da8dbd55cadc80b7621a6226 830 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 555 573 2.9E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CDW54_RS05450 aa3b97e8da8dbd55cadc80b7621a6226 830 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 662 676 2.9E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CDW54_RS05450 aa3b97e8da8dbd55cadc80b7621a6226 830 SMART SM00382 551 696 2.2E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS05450 aa3b97e8da8dbd55cadc80b7621a6226 830 SMART SM00382 214 359 1.1E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS05450 aa3b97e8da8dbd55cadc80b7621a6226 830 Gene3D G3DSA:3.40.50.300 506 727 4.0E-53 T 28-03-2018 CDW54_RS05450 aa3b97e8da8dbd55cadc80b7621a6226 830 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 219 337 2.3E-13 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CDW54_RS05450 aa3b97e8da8dbd55cadc80b7621a6226 830 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 16 68 9.3E-14 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CDW54_RS05450 aa3b97e8da8dbd55cadc80b7621a6226 830 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 96 145 1.0E-6 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CDW54_RS05450 aa3b97e8da8dbd55cadc80b7621a6226 830 Gene3D G3DSA:3.40.50.300 208 356 1.0E-19 T 28-03-2018 CDW54_RS09635 51a312ba51fc79eaa85a4d9b900a492f 71 PRINTS PR00124 ATP synthase C subunit signature 43 68 7.2E-17 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS09635 51a312ba51fc79eaa85a4d9b900a492f 71 PRINTS PR00124 ATP synthase C subunit signature 26 41 7.2E-17 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS09635 51a312ba51fc79eaa85a4d9b900a492f 71 PRINTS PR00124 ATP synthase C subunit signature 5 24 7.2E-17 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS09635 51a312ba51fc79eaa85a4d9b900a492f 71 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 13 70 9.3E-31 T 28-03-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CDW54_RS09635 51a312ba51fc79eaa85a4d9b900a492f 71 Pfam PF00137 ATP synthase subunit C 4 67 4.2E-15 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CDW54_RS09635 51a312ba51fc79eaa85a4d9b900a492f 71 Hamap MF_01396 ATP synthase subunit c [atpH]. 3 68 14.907 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS09635 51a312ba51fc79eaa85a4d9b900a492f 71 Gene3D G3DSA:1.20.20.10 1 70 1.9E-20 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CDW54_RS09635 51a312ba51fc79eaa85a4d9b900a492f 71 ProSitePatterns PS00605 ATP synthase c subunit signature. 33 54 - T 28-03-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS09635 51a312ba51fc79eaa85a4d9b900a492f 71 SUPERFAMILY SSF81333 2 70 1.18E-19 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CDW54_RS12450 c9e00152a7b11839abef728fdb503095 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 227 240 6.3E-31 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CDW54_RS12450 c9e00152a7b11839abef728fdb503095 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 200 211 6.3E-31 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CDW54_RS12450 c9e00152a7b11839abef728fdb503095 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 278 294 6.3E-31 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CDW54_RS12450 c9e00152a7b11839abef728fdb503095 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 73 84 6.3E-31 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CDW54_RS12450 c9e00152a7b11839abef728fdb503095 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 302 315 6.3E-31 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CDW54_RS12450 c9e00152a7b11839abef728fdb503095 880 SUPERFAMILY SSF55186 556 715 6.02E-52 T 28-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CDW54_RS12450 c9e00152a7b11839abef728fdb503095 880 SMART SM00863 657 700 1.5E-21 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CDW54_RS12450 c9e00152a7b11839abef728fdb503095 880 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 880 179.64 T 28-03-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 CDW54_RS12450 c9e00152a7b11839abef728fdb503095 880 SUPERFAMILY SSF50447 457 553 9.53E-16 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CDW54_RS12450 c9e00152a7b11839abef728fdb503095 880 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 657 700 5.7E-19 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CDW54_RS12450 c9e00152a7b11839abef728fdb503095 880 Pfam PF02272 DHHA1 domain 738 877 4.0E-27 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CDW54_RS12450 c9e00152a7b11839abef728fdb503095 880 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 8 860 0.0 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CDW54_RS12450 c9e00152a7b11839abef728fdb503095 880 Gene3D G3DSA:3.30.980.10 557 717 6.3E-46 T 28-03-2018 CDW54_RS12450 c9e00152a7b11839abef728fdb503095 880 Gene3D G3DSA:3.30.930.10 3 243 2.0E-99 T 28-03-2018 CDW54_RS12450 c9e00152a7b11839abef728fdb503095 880 SUPERFAMILY SSF101353 247 445 9.81E-67 T 28-03-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 CDW54_RS12450 c9e00152a7b11839abef728fdb503095 880 SUPERFAMILY SSF55681 5 246 1.76E-89 T 28-03-2018 CDW54_RS12450 c9e00152a7b11839abef728fdb503095 880 Pfam PF01411 tRNA synthetases class II (A) 8 559 2.2E-202 T 28-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 CDW54_RS11835 ba8805c3d6d29dbcc912b3a2a1d3e8b2 185 Pfam PF03780 Asp23 family, cell envelope-related function 25 131 5.8E-32 T 28-03-2018 IPR005531 Alkaline shock protein Asp23 CDW54_RS03495 188f397990b868e935ff098b3ac820bb 206 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 203 28.527 T 28-03-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 CDW54_RS03495 188f397990b868e935ff098b3ac820bb 206 Pfam PF02525 Flavodoxin-like fold 3 201 8.5E-42 T 28-03-2018 IPR003680 Flavodoxin-like fold CDW54_RS03495 188f397990b868e935ff098b3ac820bb 206 Gene3D G3DSA:3.40.50.360 3 206 2.0E-35 T 28-03-2018 IPR029039 Flavoprotein-like domain CDW54_RS03495 188f397990b868e935ff098b3ac820bb 206 SUPERFAMILY SSF52218 1 205 5.82E-48 T 28-03-2018 IPR029039 Flavoprotein-like domain CDW54_RS04855 3da8b24e881c2b3b43a8ddf243007d79 525 SUPERFAMILY SSF90257 29 110 6.54E-5 T 28-03-2018 CDW54_RS04855 3da8b24e881c2b3b43a8ddf243007d79 525 Pfam PF00877 NlpC/P60 family 423 514 1.2E-24 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CDW54_RS04855 3da8b24e881c2b3b43a8ddf243007d79 525 Gene3D G3DSA:1.10.287.510 69 204 0.12 T 28-03-2018 CDW54_RS04855 3da8b24e881c2b3b43a8ddf243007d79 525 Gene3D G3DSA:1.10.287.510 7 68 1.9E-4 T 28-03-2018 CDW54_RS04855 3da8b24e881c2b3b43a8ddf243007d79 525 Gene3D G3DSA:3.90.1720.10 403 522 6.4E-33 T 28-03-2018 CDW54_RS04855 3da8b24e881c2b3b43a8ddf243007d79 525 SUPERFAMILY SSF54001 402 516 7.85E-38 T 28-03-2018 CDW54_RS03270 9ac18f33a21d94336e38e938ceed6a20 271 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 39 265 1.5E-61 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CDW54_RS03270 9ac18f33a21d94336e38e938ceed6a20 271 SMART SM00062 38 266 5.5E-68 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CDW54_RS03270 9ac18f33a21d94336e38e938ceed6a20 271 SMART SM00079 38 265 9.7E-4 T 28-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 CDW54_RS03270 9ac18f33a21d94336e38e938ceed6a20 271 Gene3D G3DSA:3.40.190.10 12 155 3.9E-35 T 28-03-2018 CDW54_RS03270 9ac18f33a21d94336e38e938ceed6a20 271 SUPERFAMILY SSF53850 1 267 2.08E-69 T 28-03-2018 CDW54_RS03270 9ac18f33a21d94336e38e938ceed6a20 271 Gene3D G3DSA:3.40.190.10 156 271 3.9E-18 T 28-03-2018 CDW54_RS06920 3a1bfd02c82e1c861e7c2f966f7d06e4 312 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 151 4.9E-41 T 28-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CDW54_RS06920 3a1bfd02c82e1c861e7c2f966f7d06e4 312 SUPERFAMILY SSF48179 179 306 2.18E-28 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CDW54_RS06920 3a1bfd02c82e1c861e7c2f966f7d06e4 312 Gene3D G3DSA:1.10.1040.10 179 312 4.9E-30 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CDW54_RS06920 3a1bfd02c82e1c861e7c2f966f7d06e4 312 SUPERFAMILY SSF51735 1 144 4.39E-20 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS06920 3a1bfd02c82e1c861e7c2f966f7d06e4 312 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 307 1.6E-77 T 28-03-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CDW54_RS06920 3a1bfd02c82e1c861e7c2f966f7d06e4 312 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 180 306 3.0E-26 T 28-03-2018 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CDW54_RS06920 3a1bfd02c82e1c861e7c2f966f7d06e4 312 Gene3D G3DSA:3.40.50.720 1 178 2.0E-28 T 28-03-2018 CDW54_RS10525 88880ef024efb388e98765306d9be453 257 Gene3D G3DSA:3.40.50.1000 1 256 2.7E-36 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS10525 88880ef024efb388e98765306d9be453 257 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 8 251 5.3E-50 T 28-03-2018 IPR000150 Cof family GO:0016787 CDW54_RS10525 88880ef024efb388e98765306d9be453 257 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 9 224 7.3E-25 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CDW54_RS10525 88880ef024efb388e98765306d9be453 257 Pfam PF08282 haloacid dehalogenase-like hydrolase 9 251 2.6E-51 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS10525 88880ef024efb388e98765306d9be453 257 SUPERFAMILY SSF56784 9 253 7.57E-55 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS06210 ecb8100b536f18b5411c60dde2346cd2 332 SMART SM00382 124 302 5.7E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS06210 ecb8100b536f18b5411c60dde2346cd2 332 Gene3D G3DSA:1.20.120.140 4 108 1.1E-22 T 28-03-2018 CDW54_RS06210 ecb8100b536f18b5411c60dde2346cd2 332 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 51 325 2.9E-112 T 28-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 CDW54_RS06210 ecb8100b536f18b5411c60dde2346cd2 332 SMART SM00963 26 107 2.3E-23 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CDW54_RS06210 ecb8100b536f18b5411c60dde2346cd2 332 SMART SM00962 125 326 2.1E-119 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CDW54_RS06210 ecb8100b536f18b5411c60dde2346cd2 332 Pfam PF00448 SRP54-type protein, GTPase domain 126 325 5.3E-80 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CDW54_RS06210 ecb8100b536f18b5411c60dde2346cd2 332 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 50 326 63.181 T 28-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 CDW54_RS06210 ecb8100b536f18b5411c60dde2346cd2 332 Gene3D G3DSA:3.40.50.300 118 236 1.1E-19 T 28-03-2018 CDW54_RS06210 ecb8100b536f18b5411c60dde2346cd2 332 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 299 312 - T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CDW54_RS06210 ecb8100b536f18b5411c60dde2346cd2 332 Gene3D G3DSA:1.20.120.140 237 328 9.9E-23 T 28-03-2018 CDW54_RS06210 ecb8100b536f18b5411c60dde2346cd2 332 SUPERFAMILY SSF47364 22 101 1.44E-20 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CDW54_RS06210 ecb8100b536f18b5411c60dde2346cd2 332 Pfam PF02881 SRP54-type protein, helical bundle domain 37 103 1.0E-13 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CDW54_RS06210 ecb8100b536f18b5411c60dde2346cd2 332 SUPERFAMILY SSF52540 126 321 1.01E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS05930 ba3c3d273bd138771eeaba165a31a981 96 ProSitePatterns PS00050 Ribosomal protein L23 signature. 76 91 - T 28-03-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS05930 ba3c3d273bd138771eeaba165a31a981 96 SUPERFAMILY SSF54189 1 89 2.05E-30 T 28-03-2018 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS05930 ba3c3d273bd138771eeaba165a31a981 96 Gene3D G3DSA:3.30.70.330 1 96 2.2E-29 T 28-03-2018 CDW54_RS05930 ba3c3d273bd138771eeaba165a31a981 96 Pfam PF00276 Ribosomal protein L23 5 87 2.5E-30 T 28-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CDW54_RS05930 ba3c3d273bd138771eeaba165a31a981 96 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 4 94 21.649 T 28-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CDW54_RS09795 a37364bad75b4b3c2a5be385b4546777 252 SMART SM00382 30 231 2.7E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS09795 a37364bad75b4b3c2a5be385b4546777 252 Gene3D G3DSA:3.40.50.300 1 250 1.7E-60 T 28-03-2018 CDW54_RS09795 a37364bad75b4b3c2a5be385b4546777 252 SUPERFAMILY SSF52540 5 239 5.21E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS09795 a37364bad75b4b3c2a5be385b4546777 252 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS09795 a37364bad75b4b3c2a5be385b4546777 252 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 6 252 2.1E-124 T 28-03-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 CDW54_RS09795 a37364bad75b4b3c2a5be385b4546777 252 Pfam PF00005 ABC transporter 21 177 8.6E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS01790 1f6fa291a0b426b4733746fd59719aa3 324 SUPERFAMILY SSF53448 8 226 5.06E-42 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDW54_RS01790 1f6fa291a0b426b4733746fd59719aa3 324 Pfam PF00535 Glycosyl transferase family 2 8 125 7.6E-27 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CDW54_RS01790 1f6fa291a0b426b4733746fd59719aa3 324 Gene3D G3DSA:3.90.550.10 2 301 8.4E-34 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDW54_RS03445 30fd3b57e4d2eb3dcfb2a34e19d99f90 677 Gene3D G3DSA:3.40.930.10 480 673 7.3E-11 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CDW54_RS03445 30fd3b57e4d2eb3dcfb2a34e19d99f90 677 Gene3D G3DSA:1.10.10.10 70 150 9.2E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS03445 30fd3b57e4d2eb3dcfb2a34e19d99f90 677 SUPERFAMILY SSF63520 297 399 2.09E-17 T 28-03-2018 IPR011608 PRD domain GO:0006355 CDW54_RS03445 30fd3b57e4d2eb3dcfb2a34e19d99f90 677 Pfam PF08279 HTH domain 6 47 6.3E-6 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CDW54_RS03445 30fd3b57e4d2eb3dcfb2a34e19d99f90 677 Gene3D G3DSA:1.10.10.10 1 65 1.3E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS03445 30fd3b57e4d2eb3dcfb2a34e19d99f90 677 SUPERFAMILY SSF55804 521 668 1.57E-16 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CDW54_RS03445 30fd3b57e4d2eb3dcfb2a34e19d99f90 677 Pfam PF00874 PRD domain 306 394 9.8E-16 T 28-03-2018 IPR011608 PRD domain GO:0006355 CDW54_RS03445 30fd3b57e4d2eb3dcfb2a34e19d99f90 677 Pfam PF05043 Mga helix-turn-helix domain 89 158 7.9E-9 T 28-03-2018 IPR007737 Mga helix-turn-helix domain CDW54_RS03445 30fd3b57e4d2eb3dcfb2a34e19d99f90 677 Gene3D G3DSA:1.10.1790.10 284 399 1.6E-17 T 28-03-2018 IPR011608 PRD domain GO:0006355 CDW54_RS03445 30fd3b57e4d2eb3dcfb2a34e19d99f90 677 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 550 669 1.2E-9 T 28-03-2018 IPR002178 PTS EIIA type-2 domain CDW54_RS03445 30fd3b57e4d2eb3dcfb2a34e19d99f90 677 Gene3D G3DSA:1.10.1790.10 188 283 2.7E-5 T 28-03-2018 IPR011608 PRD domain GO:0006355 CDW54_RS03445 30fd3b57e4d2eb3dcfb2a34e19d99f90 677 Gene3D G3DSA:3.40.50.2300 403 479 1.0E-10 T 28-03-2018 CDW54_RS02280 9608a4df21d745c8ce95c58d578edee6 504 Gene3D G3DSA:3.40.50.980 154 307 1.2E-34 T 28-03-2018 CDW54_RS02280 9608a4df21d745c8ce95c58d578edee6 504 Gene3D G3DSA:3.30.300.30 397 503 1.3E-27 T 28-03-2018 CDW54_RS02280 9608a4df21d745c8ce95c58d578edee6 504 Hamap MF_00593 D-alanine--poly(phosphoribitol) ligase subunit 1 [dltA]. 1 503 221.651 T 28-03-2018 IPR010072 D-alanine--poly(phosphoribitol) ligase subunit 1 GO:0005524|GO:0047473|GO:0070395 KEGG: 00473+6.1.1.13 CDW54_RS02280 9608a4df21d745c8ce95c58d578edee6 504 Pfam PF13193 AMP-binding enzyme C-terminal domain 413 491 2.2E-10 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CDW54_RS02280 9608a4df21d745c8ce95c58d578edee6 504 ProSitePatterns PS00455 Putative AMP-binding domain signature. 148 159 - T 28-03-2018 IPR020845 AMP-binding, conserved site CDW54_RS02280 9608a4df21d745c8ce95c58d578edee6 504 TIGRFAM TIGR01734 D-ala-DACP-lig: D-alanine--poly(phosphoribitol) ligase, subunit 1 6 502 1.6E-206 T 28-03-2018 IPR010072 D-alanine--poly(phosphoribitol) ligase subunit 1 GO:0005524|GO:0047473|GO:0070395 KEGG: 00473+6.1.1.13 CDW54_RS02280 9608a4df21d745c8ce95c58d578edee6 504 Pfam PF00501 AMP-binding enzyme 16 403 2.1E-78 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CDW54_RS02280 9608a4df21d745c8ce95c58d578edee6 504 Gene3D G3DSA:2.30.38.10 308 396 5.6E-20 T 28-03-2018 CDW54_RS02280 9608a4df21d745c8ce95c58d578edee6 504 Gene3D G3DSA:3.40.50.980 2 153 1.4E-26 T 28-03-2018 CDW54_RS02280 9608a4df21d745c8ce95c58d578edee6 504 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 30 428 2.4E-104 T 28-03-2018 IPR010071 Amino acid adenylation domain CDW54_RS02280 9608a4df21d745c8ce95c58d578edee6 504 SUPERFAMILY SSF56801 4 502 1.7E-118 T 28-03-2018 CDW54_RS04435 824b7b189150f070f0905b634f3b70dc 204 Pfam PF04854 Protein of unknown function, DUF624 17 91 2.7E-12 T 28-03-2018 IPR006938 Protein of unknown function DUF624 CDW54_RS04830 7354472c8062c20af1e59d8c20e952bd 324 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 152 319 7.0E-41 T 28-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 CDW54_RS04830 7354472c8062c20af1e59d8c20e952bd 324 Gene3D G3DSA:3.40.50.720 12 150 4.0E-33 T 28-03-2018 CDW54_RS04830 7354472c8062c20af1e59d8c20e952bd 324 SUPERFAMILY SSF51735 6 151 1.72E-53 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS04830 7354472c8062c20af1e59d8c20e952bd 324 Gene3D G3DSA:3.90.110.10 151 322 3.0E-51 T 28-03-2018 CDW54_RS04830 7354472c8062c20af1e59d8c20e952bd 324 Hamap MF_00488 L-lactate dehydrogenase [ldh]. 10 318 45.875 T 28-03-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 CDW54_RS04830 7354472c8062c20af1e59d8c20e952bd 324 TIGRFAM TIGR01771 L-LDH-NAD: L-lactate dehydrogenase 15 312 1.9E-126 T 28-03-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 CDW54_RS04830 7354472c8062c20af1e59d8c20e952bd 324 SUPERFAMILY SSF56327 150 317 2.88E-56 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CDW54_RS04830 7354472c8062c20af1e59d8c20e952bd 324 PIRSF PIRSF000102 7 323 1.1E-106 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CDW54_RS04830 7354472c8062c20af1e59d8c20e952bd 324 PRINTS PR00086 L-lactate dehydrogenase signature 37 61 2.8E-48 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CDW54_RS04830 7354472c8062c20af1e59d8c20e952bd 324 PRINTS PR00086 L-lactate dehydrogenase signature 123 143 2.8E-48 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CDW54_RS04830 7354472c8062c20af1e59d8c20e952bd 324 PRINTS PR00086 L-lactate dehydrogenase signature 177 190 2.8E-48 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CDW54_RS04830 7354472c8062c20af1e59d8c20e952bd 324 PRINTS PR00086 L-lactate dehydrogenase signature 12 36 2.8E-48 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CDW54_RS04830 7354472c8062c20af1e59d8c20e952bd 324 PRINTS PR00086 L-lactate dehydrogenase signature 147 165 2.8E-48 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CDW54_RS04830 7354472c8062c20af1e59d8c20e952bd 324 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 12 149 1.7E-47 T 28-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 CDW54_RS04830 7354472c8062c20af1e59d8c20e952bd 324 ProSitePatterns PS00064 L-lactate dehydrogenase active site. 179 185 - T 28-03-2018 IPR018177 L-lactate dehydrogenase, active site GO:0004459|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 CDW54_RS01390 d4cd47a2db359e69be23a76a3cc84424 59 SUPERFAMILY SSF57829 1 55 1.4E-22 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CDW54_RS01390 d4cd47a2db359e69be23a76a3cc84424 59 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 56 4.0E-28 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS01390 d4cd47a2db359e69be23a76a3cc84424 59 Gene3D G3DSA:2.20.28.20 24 49 4.9E-4 T 28-03-2018 CDW54_RS01390 d4cd47a2db359e69be23a76a3cc84424 59 Pfam PF01783 Ribosomal L32p protein family 2 56 1.3E-26 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS01390 d4cd47a2db359e69be23a76a3cc84424 59 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 55 21.199 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS02620 fbfa793cbddbde475066b1d31110542f 277 SUPERFAMILY SSF56112 16 274 5.58E-49 T 28-03-2018 IPR011009 Protein kinase-like domain CDW54_RS02620 fbfa793cbddbde475066b1d31110542f 277 Pfam PF03881 Fructosamine kinase 15 276 1.7E-84 T 28-03-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 CDW54_RS02620 fbfa793cbddbde475066b1d31110542f 277 PIRSF PIRSF006221 3 277 4.6E-86 T 28-03-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 CDW54_RS02620 fbfa793cbddbde475066b1d31110542f 277 Gene3D G3DSA:3.90.1200.10 90 267 2.6E-19 T 28-03-2018 CDW54_RS02620 fbfa793cbddbde475066b1d31110542f 277 Gene3D G3DSA:3.30.200.20 1 84 4.2E-19 T 28-03-2018 CDW54_RS09750 f7e9c54496285a48599da07db7f11c67 844 Gene3D G3DSA:3.40.50.300 397 585 1.9E-52 T 28-03-2018 CDW54_RS09750 f7e9c54496285a48599da07db7f11c67 844 SMART SM00957 5 382 8.3E-285 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CDW54_RS09750 f7e9c54496285a48599da07db7f11c67 844 SUPERFAMILY SSF81767 225 348 1.7E-48 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CDW54_RS09750 f7e9c54496285a48599da07db7f11c67 844 SMART SM00958 226 338 3.0E-70 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CDW54_RS09750 f7e9c54496285a48599da07db7f11c67 844 SUPERFAMILY SSF52540 348 395 8.38E-82 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS09750 f7e9c54496285a48599da07db7f11c67 844 SUPERFAMILY SSF52540 11 226 8.38E-82 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS09750 f7e9c54496285a48599da07db7f11c67 844 PRINTS PR00906 SecA protein signature 168 188 2.9E-73 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CDW54_RS09750 f7e9c54496285a48599da07db7f11c67 844 PRINTS PR00906 SecA protein signature 61 85 2.9E-73 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CDW54_RS09750 f7e9c54496285a48599da07db7f11c67 844 PRINTS PR00906 SecA protein signature 115 125 2.9E-73 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CDW54_RS09750 f7e9c54496285a48599da07db7f11c67 844 PRINTS PR00906 SecA protein signature 393 406 2.9E-73 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CDW54_RS09750 f7e9c54496285a48599da07db7f11c67 844 PRINTS PR00906 SecA protein signature 99 113 2.9E-73 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CDW54_RS09750 f7e9c54496285a48599da07db7f11c67 844 PRINTS PR00906 SecA protein signature 319 341 2.9E-73 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CDW54_RS09750 f7e9c54496285a48599da07db7f11c67 844 PRINTS PR00906 SecA protein signature 356 373 2.9E-73 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CDW54_RS09750 f7e9c54496285a48599da07db7f11c67 844 Hamap MF_01382 Protein translocase subunit SecA [secA]. 3 782 19.637 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CDW54_RS09750 f7e9c54496285a48599da07db7f11c67 844 Pfam PF07516 SecA Wing and Scaffold domain 570 779 1.6E-62 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CDW54_RS09750 f7e9c54496285a48599da07db7f11c67 844 SUPERFAMILY SSF81886 819 831 1.26E-79 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CDW54_RS09750 f7e9c54496285a48599da07db7f11c67 844 SUPERFAMILY SSF81886 572 790 1.26E-79 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CDW54_RS09750 f7e9c54496285a48599da07db7f11c67 844 Pfam PF07517 SecA DEAD-like domain 10 382 7.5E-130 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CDW54_RS09750 f7e9c54496285a48599da07db7f11c67 844 Gene3D G3DSA:3.40.50.300 7 269 6.1E-55 T 28-03-2018 CDW54_RS09750 f7e9c54496285a48599da07db7f11c67 844 Gene3D G3DSA:3.40.50.300 292 396 1.1E-8 T 28-03-2018 CDW54_RS09750 f7e9c54496285a48599da07db7f11c67 844 Pfam PF01043 SecA preprotein cross-linking domain 230 338 2.5E-41 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CDW54_RS09750 f7e9c54496285a48599da07db7f11c67 844 Gene3D G3DSA:3.10.450.50 675 843 1.1E-46 T 28-03-2018 CDW54_RS09750 f7e9c54496285a48599da07db7f11c67 844 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 26 496 6.8E-242 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CDW54_RS09750 f7e9c54496285a48599da07db7f11c67 844 ProSitePatterns PS01312 SecA family signature. 480 495 - T 28-03-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 CDW54_RS09750 f7e9c54496285a48599da07db7f11c67 844 Gene3D G3DSA:1.10.3060.10 586 674 9.9E-27 T 28-03-2018 CDW54_RS09750 f7e9c54496285a48599da07db7f11c67 844 Pfam PF02810 SEC-C motif 823 841 3.9E-10 T 28-03-2018 IPR004027 SEC-C motif CDW54_RS09750 f7e9c54496285a48599da07db7f11c67 844 SUPERFAMILY SSF52540 396 566 5.52E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS11985 8ccf3457f6a434fe634738013bd2fb00 588 Pfam PF02903 Alpha amylase, N-terminal ig-like domain 1 124 4.9E-40 T 28-03-2018 IPR004185 Glycoside hydrolase, family 13, N-terminal Ig-like domain GO:0004553|GO:0005975 CDW54_RS11985 8ccf3457f6a434fe634738013bd2fb00 588 Pfam PF00128 Alpha amylase, catalytic domain 176 481 1.2E-81 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CDW54_RS11985 8ccf3457f6a434fe634738013bd2fb00 588 PIRSF PIRSF001024 116 579 4.9E-55 T 28-03-2018 CDW54_RS11985 8ccf3457f6a434fe634738013bd2fb00 588 SMART SM00642 142 509 4.5E-121 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CDW54_RS11985 8ccf3457f6a434fe634738013bd2fb00 588 SUPERFAMILY SSF51011 519 572 4.93E-5 T 28-03-2018 CDW54_RS11985 8ccf3457f6a434fe634738013bd2fb00 588 Gene3D G3DSA:2.60.40.10 1 128 1.6E-36 T 28-03-2018 IPR013783 Immunoglobulin-like fold CDW54_RS11985 8ccf3457f6a434fe634738013bd2fb00 588 SUPERFAMILY SSF51445 65 512 2.11E-125 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CDW54_RS11985 8ccf3457f6a434fe634738013bd2fb00 588 Gene3D G3DSA:3.20.20.80 129 511 1.7E-113 T 28-03-2018 CDW54_RS10835 d65ad33e5c0484c3c3a1ddce0768658f 185 Gene3D G3DSA:1.10.132.20 73 184 1.8E-38 T 28-03-2018 CDW54_RS10835 d65ad33e5c0484c3c3a1ddce0768658f 185 Gene3D G3DSA:1.10.132.20 2 72 2.4E-11 T 28-03-2018 CDW54_RS10835 d65ad33e5c0484c3c3a1ddce0768658f 185 Pfam PF01765 Ribosome recycling factor 20 183 2.2E-64 T 28-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CDW54_RS10835 d65ad33e5c0484c3c3a1ddce0768658f 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 27.615 T 28-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 CDW54_RS10835 d65ad33e5c0484c3c3a1ddce0768658f 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 10 185 2.5E-71 T 28-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 CDW54_RS10835 d65ad33e5c0484c3c3a1ddce0768658f 185 SUPERFAMILY SSF55194 3 184 2.88E-71 T 28-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CDW54_RS05300 bb4e49f2aacdcaee4eb48f2c4eb4f584 341 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 3 123 2.8E-30 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CDW54_RS05300 bb4e49f2aacdcaee4eb48f2c4eb4f584 341 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 139 227 1.0E-7 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CDW54_RS05300 bb4e49f2aacdcaee4eb48f2c4eb4f584 341 Gene3D G3DSA:3.30.360.10 147 341 5.1E-23 T 28-03-2018 CDW54_RS05300 bb4e49f2aacdcaee4eb48f2c4eb4f584 341 SUPERFAMILY SSF55347 135 302 1.18E-22 T 28-03-2018 CDW54_RS05300 bb4e49f2aacdcaee4eb48f2c4eb4f584 341 Gene3D G3DSA:3.40.50.720 1 146 1.7E-39 T 28-03-2018 CDW54_RS05300 bb4e49f2aacdcaee4eb48f2c4eb4f584 341 SUPERFAMILY SSF51735 3 151 2.12E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS06000 ab0e8fe5e4a5004d64283cc0a4ed06f5 118 Gene3D G3DSA:3.30.420.100 2 118 1.1E-45 T 28-03-2018 CDW54_RS06000 ab0e8fe5e4a5004d64283cc0a4ed06f5 118 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 6 118 30.273 T 28-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS06000 ab0e8fe5e4a5004d64283cc0a4ed06f5 118 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 7 118 1.5E-47 T 28-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS06000 ab0e8fe5e4a5004d64283cc0a4ed06f5 118 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 6 118 1.5E-50 T 28-03-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS06000 ab0e8fe5e4a5004d64283cc0a4ed06f5 118 SUPERFAMILY SSF53137 7 116 3.05E-55 T 28-03-2018 CDW54_RS12710 bc8b71cca97417ffc595b00731f1bd16 273 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 74 82 - T 28-03-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDW54_RS12710 bc8b71cca97417ffc595b00731f1bd16 273 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 184 194 - T 28-03-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDW54_RS12710 bc8b71cca97417ffc595b00731f1bd16 273 Hamap MF_00258 Glutamate racemase [murI]. 8 261 41.026 T 28-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDW54_RS12710 bc8b71cca97417ffc595b00731f1bd16 273 Gene3D G3DSA:3.40.50.1860 119 272 6.6E-42 T 28-03-2018 CDW54_RS12710 bc8b71cca97417ffc595b00731f1bd16 273 Gene3D G3DSA:3.40.50.1860 6 118 1.3E-27 T 28-03-2018 CDW54_RS12710 bc8b71cca97417ffc595b00731f1bd16 273 Pfam PF01177 Asp/Glu/Hydantoin racemase 10 218 1.7E-38 T 28-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDW54_RS12710 bc8b71cca97417ffc595b00731f1bd16 273 SUPERFAMILY SSF53681 113 268 4.41E-40 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDW54_RS12710 bc8b71cca97417ffc595b00731f1bd16 273 TIGRFAM TIGR00067 glut_race: glutamate racemase 10 259 3.5E-84 T 28-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDW54_RS12710 bc8b71cca97417ffc595b00731f1bd16 273 SUPERFAMILY SSF53681 9 111 7.52E-36 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDW54_RS09735 0504ca5c95a76ea81c5d26590c8eb582 358 SMART SM00490 239 322 8.9E-6 T 28-03-2018 IPR001650 Helicase, C-terminal CDW54_RS09735 0504ca5c95a76ea81c5d26590c8eb582 358 Gene3D G3DSA:3.40.50.300 198 358 7.9E-22 T 28-03-2018 CDW54_RS09735 0504ca5c95a76ea81c5d26590c8eb582 358 SMART SM00487 16 198 2.4E-18 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CDW54_RS09735 0504ca5c95a76ea81c5d26590c8eb582 358 Gene3D G3DSA:3.40.50.300 8 184 2.5E-23 T 28-03-2018 CDW54_RS09735 0504ca5c95a76ea81c5d26590c8eb582 358 Pfam PF04851 Type III restriction enzyme, res subunit 19 166 5.1E-9 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CDW54_RS09735 0504ca5c95a76ea81c5d26590c8eb582 358 SUPERFAMILY SSF52540 36 336 4.31E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS09735 0504ca5c95a76ea81c5d26590c8eb582 358 Pfam PF00271 Helicase conserved C-terminal domain 211 322 6.9E-11 T 28-03-2018 IPR001650 Helicase, C-terminal CDW54_RS07995 dbab0d273f21c6f25e065fab6c3f8868 298 Gene3D G3DSA:3.10.350.10 229 298 3.1E-5 T 28-03-2018 CDW54_RS09285 291cbd76f8ca2b4db0ed84ae164ab690 440 PIRSF PIRSF005348 2 440 1.8E-150 T 28-03-2018 IPR004679 2-hydroxycarboxylate transporter GO:0008514|GO:0015711|GO:0016021 CDW54_RS09285 291cbd76f8ca2b4db0ed84ae164ab690 440 Pfam PF03390 2-hydroxycarboxylate transporter family 24 433 7.8E-146 T 28-03-2018 IPR004679 2-hydroxycarboxylate transporter GO:0008514|GO:0015711|GO:0016021 CDW54_RS09760 f152968be5e241d4e4e1de21ffddf4df 228 Pfam PF00005 ABC transporter 19 165 3.9E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS09760 f152968be5e241d4e4e1de21ffddf4df 228 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS09760 f152968be5e241d4e4e1de21ffddf4df 228 Gene3D G3DSA:3.40.50.300 1 225 4.3E-64 T 28-03-2018 CDW54_RS09760 f152968be5e241d4e4e1de21ffddf4df 228 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 214 3.5E-90 T 28-03-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 CDW54_RS09760 f152968be5e241d4e4e1de21ffddf4df 228 SUPERFAMILY SSF52540 1 220 3.19E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS09760 f152968be5e241d4e4e1de21ffddf4df 228 SMART SM00382 27 221 3.1E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS02605 8a213e0c0027da7c53abe5c597700bd7 277 Pfam PF01904 Protein of unknown function DUF72 18 260 5.4E-52 T 28-03-2018 IPR002763 Protein of unknown function DUF72 CDW54_RS02605 8a213e0c0027da7c53abe5c597700bd7 277 Gene3D G3DSA:3.20.20.410 1 277 7.7E-68 T 28-03-2018 IPR002763 Protein of unknown function DUF72 CDW54_RS02605 8a213e0c0027da7c53abe5c597700bd7 277 SUPERFAMILY SSF117396 1 264 2.49E-75 T 28-03-2018 IPR002763 Protein of unknown function DUF72 CDW54_RS07255 2b28ccab157a65a724220aa34b8cda51 697 SUPERFAMILY SSF52794 406 479 3.92E-9 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CDW54_RS07255 2b28ccab157a65a724220aa34b8cda51 697 SUPERFAMILY SSF55804 547 693 6.8E-38 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CDW54_RS07255 2b28ccab157a65a724220aa34b8cda51 697 Pfam PF00874 PRD domain 304 392 7.2E-15 T 28-03-2018 IPR011608 PRD domain GO:0006355 CDW54_RS07255 2b28ccab157a65a724220aa34b8cda51 697 Gene3D G3DSA:1.10.1790.10 291 398 2.0E-15 T 28-03-2018 IPR011608 PRD domain GO:0006355 CDW54_RS07255 2b28ccab157a65a724220aa34b8cda51 697 Pfam PF08279 HTH domain 4 39 3.1E-5 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CDW54_RS07255 2b28ccab157a65a724220aa34b8cda51 697 Gene3D G3DSA:3.40.50.2300 405 491 9.0E-15 T 28-03-2018 CDW54_RS07255 2b28ccab157a65a724220aa34b8cda51 697 Gene3D G3DSA:1.10.10.10 1 67 1.0E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS07255 2b28ccab157a65a724220aa34b8cda51 697 Gene3D G3DSA:1.10.10.10 86 152 1.2E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS07255 2b28ccab157a65a724220aa34b8cda51 697 SUPERFAMILY SSF63520 299 392 2.09E-15 T 28-03-2018 IPR011608 PRD domain GO:0006355 CDW54_RS07255 2b28ccab157a65a724220aa34b8cda51 697 Pfam PF05043 Mga helix-turn-helix domain 112 164 4.7E-6 T 28-03-2018 IPR007737 Mga helix-turn-helix domain CDW54_RS07255 2b28ccab157a65a724220aa34b8cda51 697 Gene3D G3DSA:3.40.930.10 547 693 1.2E-34 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CDW54_RS07255 2b28ccab157a65a724220aa34b8cda51 697 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 552 691 4.7E-32 T 28-03-2018 IPR002178 PTS EIIA type-2 domain CDW54_RS00115 8d91a37ed96b71a45c9215e6eaa21a7e 317 Gene3D G3DSA:3.30.420.10 156 314 9.3E-18 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS00115 8d91a37ed96b71a45c9215e6eaa21a7e 317 SUPERFAMILY SSF53098 160 309 5.5E-17 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS00115 8d91a37ed96b71a45c9215e6eaa21a7e 317 Gene3D G3DSA:1.10.10.60 7 68 3.1E-4 T 28-03-2018 CDW54_RS00800 8d91a37ed96b71a45c9215e6eaa21a7e 317 Gene3D G3DSA:3.30.420.10 156 314 9.3E-18 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS00800 8d91a37ed96b71a45c9215e6eaa21a7e 317 SUPERFAMILY SSF53098 160 309 5.5E-17 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS00800 8d91a37ed96b71a45c9215e6eaa21a7e 317 Gene3D G3DSA:1.10.10.60 7 68 3.1E-4 T 28-03-2018 CDW54_RS03120 8d91a37ed96b71a45c9215e6eaa21a7e 317 Gene3D G3DSA:3.30.420.10 156 314 9.3E-18 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS03120 8d91a37ed96b71a45c9215e6eaa21a7e 317 SUPERFAMILY SSF53098 160 309 5.5E-17 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS03120 8d91a37ed96b71a45c9215e6eaa21a7e 317 Gene3D G3DSA:1.10.10.60 7 68 3.1E-4 T 28-03-2018 CDW54_RS12245 4d4e8cb54c9e7690e69e1acf605d4db6 601 Gene3D G3DSA:1.50.10.10 250 592 8.9E-41 T 28-03-2018 CDW54_RS12245 4d4e8cb54c9e7690e69e1acf605d4db6 601 Pfam PF17389 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain 253 589 3.7E-19 T 28-03-2018 IPR035396 Alpha-L-rhamnosidase, six-hairpin glycosidase domain CDW54_RS12245 4d4e8cb54c9e7690e69e1acf605d4db6 601 Gene3D G3DSA:2.60.120.260 9 157 1.1E-52 T 28-03-2018 IPR008979 Galactose-binding domain-like CDW54_RS12245 4d4e8cb54c9e7690e69e1acf605d4db6 601 Gene3D G3DSA:2.60.120.260 158 248 8.1E-18 T 28-03-2018 IPR008979 Galactose-binding domain-like CDW54_RS12245 4d4e8cb54c9e7690e69e1acf605d4db6 601 SUPERFAMILY SSF48208 243 599 5.03E-34 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CDW54_RS00605 c1c95782a96840b7e2ea458f7f9bc34a 240 Pfam PF01026 TatD related DNase 4 236 2.2E-37 T 28-03-2018 IPR001130 TatD family GO:0016788 CDW54_RS00605 c1c95782a96840b7e2ea458f7f9bc34a 240 PIRSF PIRSF005902 1 240 9.8E-38 T 28-03-2018 IPR001130 TatD family GO:0016788 CDW54_RS00605 c1c95782a96840b7e2ea458f7f9bc34a 240 Gene3D G3DSA:3.20.20.140 1 240 1.1E-44 T 28-03-2018 CDW54_RS00605 c1c95782a96840b7e2ea458f7f9bc34a 240 SUPERFAMILY SSF51556 3 238 4.95E-42 T 28-03-2018 IPR032466 Metal-dependent hydrolase CDW54_RS06600 2f8fc6ebcbbc90cc349db4f992b25be9 89 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 89 23.458 T 28-03-2018 IPR023036 Ribosomal protein S14, bacterial/plastid CDW54_RS06600 2f8fc6ebcbbc90cc349db4f992b25be9 89 SUPERFAMILY SSF57716 2 89 2.14E-28 T 28-03-2018 CDW54_RS06600 2f8fc6ebcbbc90cc349db4f992b25be9 89 Pfam PF00253 Ribosomal protein S14p/S29e 36 88 9.4E-25 T 28-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS06600 2f8fc6ebcbbc90cc349db4f992b25be9 89 Gene3D G3DSA:4.10.830.10 1 89 1.9E-32 T 28-03-2018 CDW54_RS11925 a525da517fc6f01815d3f68ce7927c4b 509 Gene3D G3DSA:3.40.30.10 1 92 1.1E-23 T 28-03-2018 CDW54_RS11925 a525da517fc6f01815d3f68ce7927c4b 509 Gene3D G3DSA:3.50.50.60 337 425 3.8E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS11925 a525da517fc6f01815d3f68ce7927c4b 509 TIGRFAM TIGR03140 AhpF: alkyl hydroperoxide reductase subunit F 1 508 1.1E-220 T 28-03-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0016651|GO:0050660|GO:0051287|GO:0055114 CDW54_RS11925 a525da517fc6f01815d3f68ce7927c4b 509 PIRSF PIRSF000238 1 509 3.8E-233 T 28-03-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0016651|GO:0050660|GO:0051287|GO:0055114 CDW54_RS11925 a525da517fc6f01815d3f68ce7927c4b 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 261 271 1.2E-66 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDW54_RS11925 a525da517fc6f01815d3f68ce7927c4b 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 345 369 1.2E-66 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDW54_RS11925 a525da517fc6f01815d3f68ce7927c4b 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 435 456 1.2E-66 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDW54_RS11925 a525da517fc6f01815d3f68ce7927c4b 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 209 231 1.2E-66 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDW54_RS11925 a525da517fc6f01815d3f68ce7927c4b 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 330 342 1.2E-66 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDW54_RS11925 a525da517fc6f01815d3f68ce7927c4b 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 469 487 1.2E-66 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDW54_RS11925 a525da517fc6f01815d3f68ce7927c4b 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 241 256 1.2E-66 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDW54_RS11925 a525da517fc6f01815d3f68ce7927c4b 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 308 316 1.2E-66 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDW54_RS11925 a525da517fc6f01815d3f68ce7927c4b 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 397 413 1.2E-66 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDW54_RS11925 a525da517fc6f01815d3f68ce7927c4b 509 SUPERFAMILY SSF52833 104 193 1.22E-20 T 28-03-2018 IPR012336 Thioredoxin-like fold CDW54_RS11925 a525da517fc6f01815d3f68ce7927c4b 509 Gene3D G3DSA:3.50.50.60 426 503 3.0E-5 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS11925 a525da517fc6f01815d3f68ce7927c4b 509 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 208 492 4.7E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS11925 a525da517fc6f01815d3f68ce7927c4b 509 Gene3D G3DSA:3.40.30.10 101 195 4.4E-6 T 28-03-2018 CDW54_RS11925 a525da517fc6f01815d3f68ce7927c4b 509 Pfam PF13192 Thioredoxin domain 123 193 1.0E-9 T 28-03-2018 IPR012336 Thioredoxin-like fold CDW54_RS11925 a525da517fc6f01815d3f68ce7927c4b 509 SUPERFAMILY SSF52833 1 99 2.86E-26 T 28-03-2018 IPR012336 Thioredoxin-like fold CDW54_RS11925 a525da517fc6f01815d3f68ce7927c4b 509 Gene3D G3DSA:3.50.50.60 202 336 3.9E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS11925 a525da517fc6f01815d3f68ce7927c4b 509 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 349 367 1.5E-36 T 28-03-2018 CDW54_RS11925 a525da517fc6f01815d3f68ce7927c4b 509 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 459 481 1.5E-36 T 28-03-2018 CDW54_RS11925 a525da517fc6f01815d3f68ce7927c4b 509 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 210 229 1.5E-36 T 28-03-2018 CDW54_RS11925 a525da517fc6f01815d3f68ce7927c4b 509 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 433 449 1.5E-36 T 28-03-2018 CDW54_RS11925 a525da517fc6f01815d3f68ce7927c4b 509 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 307 325 1.5E-36 T 28-03-2018 CDW54_RS11925 a525da517fc6f01815d3f68ce7927c4b 509 SUPERFAMILY SSF51905 205 506 5.83E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS11925 a525da517fc6f01815d3f68ce7927c4b 509 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 337 357 - T 28-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 CDW54_RS04100 d762f0c6004b4a6132018339c6b88a64 223 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 8 196 30.78 T 28-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CDW54_RS04100 d762f0c6004b4a6132018339c6b88a64 223 TIGRFAM TIGR00567 3mg: DNA-3-methyladenine glycosylase 9 196 4.8E-49 T 28-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CDW54_RS04100 d762f0c6004b4a6132018339c6b88a64 223 SUPERFAMILY SSF50486 6 203 2.67E-60 T 28-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 CDW54_RS04100 d762f0c6004b4a6132018339c6b88a64 223 Gene3D G3DSA:3.10.300.10 3 204 3.8E-61 T 28-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CDW54_RS04100 d762f0c6004b4a6132018339c6b88a64 223 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 11 193 2.1E-53 T 28-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CDW54_RS07010 8aafc1306b6a22d51dc4c06f32f465d3 626 Gene3D G3DSA:3.40.1110.10 332 437 1.5E-23 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CDW54_RS07010 8aafc1306b6a22d51dc4c06f32f465d3 626 Gene3D G3DSA:1.20.1110.10 62 331 6.1E-31 T 28-03-2018 CDW54_RS07010 8aafc1306b6a22d51dc4c06f32f465d3 626 PRINTS PR00941 Cadmium-transporting ATPase signature 203 217 1.2E-7 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CDW54_RS07010 8aafc1306b6a22d51dc4c06f32f465d3 626 PRINTS PR00941 Cadmium-transporting ATPase signature 102 122 1.2E-7 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CDW54_RS07010 8aafc1306b6a22d51dc4c06f32f465d3 626 PRINTS PR00941 Cadmium-transporting ATPase signature 184 200 1.2E-7 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CDW54_RS07010 8aafc1306b6a22d51dc4c06f32f465d3 626 SUPERFAMILY SSF56784 308 328 1.33E-50 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS07010 8aafc1306b6a22d51dc4c06f32f465d3 626 SUPERFAMILY SSF56784 368 612 1.33E-50 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS07010 8aafc1306b6a22d51dc4c06f32f465d3 626 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 312 318 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CDW54_RS07010 8aafc1306b6a22d51dc4c06f32f465d3 626 Pfam PF00122 E1-E2 ATPase 118 290 8.4E-47 T 28-03-2018 CDW54_RS07010 8aafc1306b6a22d51dc4c06f32f465d3 626 SUPERFAMILY SSF81653 125 218 1.11E-25 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CDW54_RS07010 8aafc1306b6a22d51dc4c06f32f465d3 626 ProSitePatterns PS01229 Hypothetical cof family signature 2. 512 534 - T 28-03-2018 CDW54_RS07010 8aafc1306b6a22d51dc4c06f32f465d3 626 Pfam PF00702 haloacid dehalogenase-like hydrolase 306 526 3.0E-41 T 28-03-2018 CDW54_RS07010 8aafc1306b6a22d51dc4c06f32f465d3 626 SUPERFAMILY SSF81665 219 304 3.01E-11 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CDW54_RS07010 8aafc1306b6a22d51dc4c06f32f465d3 626 SUPERFAMILY SSF81665 70 121 3.01E-11 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CDW54_RS07010 8aafc1306b6a22d51dc4c06f32f465d3 626 SUPERFAMILY SSF81665 561 575 3.01E-11 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CDW54_RS07010 8aafc1306b6a22d51dc4c06f32f465d3 626 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 535 547 1.2E-24 T 28-03-2018 CDW54_RS07010 8aafc1306b6a22d51dc4c06f32f465d3 626 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 459 469 1.2E-24 T 28-03-2018 CDW54_RS07010 8aafc1306b6a22d51dc4c06f32f465d3 626 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 512 531 1.2E-24 T 28-03-2018 CDW54_RS07010 8aafc1306b6a22d51dc4c06f32f465d3 626 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 168 182 1.2E-24 T 28-03-2018 CDW54_RS07010 8aafc1306b6a22d51dc4c06f32f465d3 626 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 436 447 1.2E-24 T 28-03-2018 CDW54_RS07010 8aafc1306b6a22d51dc4c06f32f465d3 626 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 310 324 1.2E-24 T 28-03-2018 CDW54_RS07010 8aafc1306b6a22d51dc4c06f32f465d3 626 Gene3D G3DSA:3.40.50.1000 438 578 4.2E-41 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS07010 8aafc1306b6a22d51dc4c06f32f465d3 626 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 52 614 6.7E-122 T 28-03-2018 CDW54_RS07010 8aafc1306b6a22d51dc4c06f32f465d3 626 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 90 594 1.6E-73 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDW54_RS07010 8aafc1306b6a22d51dc4c06f32f465d3 626 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 67 614 2.1E-173 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CDW54_RS11260 af1019b47c410c4df88626bb47530a0b 324 SUPERFAMILY SSF74650 11 323 3.61E-73 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CDW54_RS11260 af1019b47c410c4df88626bb47530a0b 324 Gene3D G3DSA:2.70.98.10 8 324 2.5E-68 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CDW54_RS11260 af1019b47c410c4df88626bb47530a0b 324 SMART SM01038 25 324 2.9E-94 T 28-03-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CDW54_RS11260 af1019b47c410c4df88626bb47530a0b 324 Pfam PF02929 Beta galactosidase small chain 28 323 1.3E-56 T 28-03-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CDW54_RS06795 3d5e3f74fc95f09cdf82c4eed6f91f8a 146 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 13 113 6.8E-24 T 28-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 CDW54_RS06795 3d5e3f74fc95f09cdf82c4eed6f91f8a 146 Gene3D G3DSA:3.10.129.10 3 145 3.4E-29 T 28-03-2018 CDW54_RS06795 3d5e3f74fc95f09cdf82c4eed6f91f8a 146 PIRSF PIRSF003230 7 141 1.0E-27 T 28-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 CDW54_RS06795 3d5e3f74fc95f09cdf82c4eed6f91f8a 146 SUPERFAMILY SSF54637 9 130 3.61E-31 T 28-03-2018 IPR029069 HotDog domain CDW54_RS06795 3d5e3f74fc95f09cdf82c4eed6f91f8a 146 Pfam PF03061 Thioesterase superfamily 19 101 2.4E-12 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CDW54_RS00055 0e974ab0a4eed6689eaf7294283cf240 488 ProSitePatterns PS01022 PTR2 family proton/oligopeptide symporters signature 1. 75 99 - T 28-03-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 CDW54_RS00055 0e974ab0a4eed6689eaf7294283cf240 488 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 6 484 3.0E-134 T 28-03-2018 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 CDW54_RS00055 0e974ab0a4eed6689eaf7294283cf240 488 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 149 161 - T 28-03-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 CDW54_RS00055 0e974ab0a4eed6689eaf7294283cf240 488 SUPERFAMILY SSF103473 274 479 7.59E-30 T 28-03-2018 IPR020846 Major facilitator superfamily domain CDW54_RS00055 0e974ab0a4eed6689eaf7294283cf240 488 SUPERFAMILY SSF103473 9 205 7.59E-30 T 28-03-2018 IPR020846 Major facilitator superfamily domain CDW54_RS00055 0e974ab0a4eed6689eaf7294283cf240 488 Pfam PF00854 POT family 87 456 5.0E-74 T 28-03-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 CDW54_RS00055 0e974ab0a4eed6689eaf7294283cf240 488 Gene3D G3DSA:1.20.1250.20 209 487 1.5E-9 T 28-03-2018 CDW54_RS00055 0e974ab0a4eed6689eaf7294283cf240 488 Gene3D G3DSA:1.20.1250.20 7 201 2.0E-19 T 28-03-2018 CDW54_RS04195 6927737333931659bfae76a16229950a 259 Pfam PF01636 Phosphotransferase enzyme family 40 196 6.4E-16 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CDW54_RS04195 6927737333931659bfae76a16229950a 259 SUPERFAMILY SSF56112 4 231 2.04E-29 T 28-03-2018 IPR011009 Protein kinase-like domain CDW54_RS04195 6927737333931659bfae76a16229950a 259 Gene3D G3DSA:3.90.1200.10 28 255 9.4E-20 T 28-03-2018 CDW54_RS00295 04ca9d352f8edd8e9318c7c5a4d0c1f9 255 Gene3D G3DSA:3.40.190.80 141 255 4.7E-18 T 28-03-2018 CDW54_RS00295 04ca9d352f8edd8e9318c7c5a4d0c1f9 255 Pfam PF00459 Inositol monophosphatase family 2 239 1.6E-39 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CDW54_RS00295 04ca9d352f8edd8e9318c7c5a4d0c1f9 255 Gene3D G3DSA:3.30.540.10 1 140 9.6E-33 T 28-03-2018 CDW54_RS00295 04ca9d352f8edd8e9318c7c5a4d0c1f9 255 PRINTS PR00377 Inositol monophosphatase superfamily signature 80 96 1.5E-25 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CDW54_RS00295 04ca9d352f8edd8e9318c7c5a4d0c1f9 255 PRINTS PR00377 Inositol monophosphatase superfamily signature 36 56 1.5E-25 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CDW54_RS00295 04ca9d352f8edd8e9318c7c5a4d0c1f9 255 PRINTS PR00377 Inositol monophosphatase superfamily signature 129 152 1.5E-25 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CDW54_RS00295 04ca9d352f8edd8e9318c7c5a4d0c1f9 255 PRINTS PR00377 Inositol monophosphatase superfamily signature 201 225 1.5E-25 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CDW54_RS00295 04ca9d352f8edd8e9318c7c5a4d0c1f9 255 PRINTS PR00377 Inositol monophosphatase superfamily signature 171 192 1.5E-25 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CDW54_RS00295 04ca9d352f8edd8e9318c7c5a4d0c1f9 255 PRINTS PR00377 Inositol monophosphatase superfamily signature 58 74 1.5E-25 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CDW54_RS00295 04ca9d352f8edd8e9318c7c5a4d0c1f9 255 SUPERFAMILY SSF56655 1 253 1.7E-58 T 28-03-2018 CDW54_RS08245 a05751c330d6bc22cedbab11b2fcc08a 372 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 219 232 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CDW54_RS08245 a05751c330d6bc22cedbab11b2fcc08a 372 Gene3D G3DSA:3.40.640.10 63 271 2.7E-49 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDW54_RS08245 a05751c330d6bc22cedbab11b2fcc08a 372 Pfam PF00155 Aminotransferase class I and II 56 359 3.7E-46 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CDW54_RS08245 a05751c330d6bc22cedbab11b2fcc08a 372 Gene3D G3DSA:3.90.1150.10 272 372 9.0E-14 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDW54_RS08245 a05751c330d6bc22cedbab11b2fcc08a 372 SUPERFAMILY SSF53383 54 370 4.39E-80 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDW54_RS05685 9e3c6bd151d491ad100b146c2f59c3cb 374 SUPERFAMILY SSF52540 1 217 6.88E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS05685 9e3c6bd151d491ad100b146c2f59c3cb 374 SUPERFAMILY SSF52540 244 351 6.88E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS05685 9e3c6bd151d491ad100b146c2f59c3cb 374 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 365 2.0E-13 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CDW54_RS05685 9e3c6bd151d491ad100b146c2f59c3cb 374 ProSitePatterns PS00618 RecF protein signature 2. 312 330 - T 28-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 CDW54_RS05685 9e3c6bd151d491ad100b146c2f59c3cb 374 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 366 4.7E-130 T 28-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 CDW54_RS05685 9e3c6bd151d491ad100b146c2f59c3cb 374 ProSitePatterns PS00617 RecF protein signature 1. 116 136 - T 28-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 CDW54_RS05685 9e3c6bd151d491ad100b146c2f59c3cb 374 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 374 102.127 T 28-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 CDW54_RS05685 9e3c6bd151d491ad100b146c2f59c3cb 374 Gene3D G3DSA:3.40.50.300 1 371 1.6E-31 T 28-03-2018 CDW54_RS06025 a5e689e1cca80ab46fc7667305534d5a 215 Hamap MF_00235 Adenylate kinase [adk]. 1 214 53.295 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CDW54_RS06025 a5e689e1cca80ab46fc7667305534d5a 215 TIGRFAM TIGR01351 adk: adenylate kinase 2 213 7.3E-81 T 28-03-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 CDW54_RS06025 a5e689e1cca80ab46fc7667305534d5a 215 Pfam PF05191 Adenylate kinase, active site lid 127 163 7.3E-14 T 28-03-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 CDW54_RS06025 a5e689e1cca80ab46fc7667305534d5a 215 Gene3D G3DSA:3.40.50.300 1 215 2.4E-60 T 28-03-2018 CDW54_RS06025 a5e689e1cca80ab46fc7667305534d5a 215 SUPERFAMILY SSF52540 1 214 6.13E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS06025 a5e689e1cca80ab46fc7667305534d5a 215 Pfam PF00406 Adenylate kinase 5 191 1.9E-58 T 28-03-2018 CDW54_RS06025 a5e689e1cca80ab46fc7667305534d5a 215 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 28-03-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CDW54_RS06025 a5e689e1cca80ab46fc7667305534d5a 215 PRINTS PR00094 Adenylate kinase signature 178 192 1.9E-31 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CDW54_RS06025 a5e689e1cca80ab46fc7667305534d5a 215 PRINTS PR00094 Adenylate kinase signature 32 46 1.9E-31 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CDW54_RS06025 a5e689e1cca80ab46fc7667305534d5a 215 PRINTS PR00094 Adenylate kinase signature 81 97 1.9E-31 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CDW54_RS06025 a5e689e1cca80ab46fc7667305534d5a 215 PRINTS PR00094 Adenylate kinase signature 4 17 1.9E-31 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CDW54_RS06025 a5e689e1cca80ab46fc7667305534d5a 215 PRINTS PR00094 Adenylate kinase signature 161 176 1.9E-31 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CDW54_RS04385 1628a19170cc836ef0783ea645271e8f 723 Pfam PF00905 Penicillin binding protein transpeptidase domain 363 633 1.5E-39 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CDW54_RS04385 1628a19170cc836ef0783ea645271e8f 723 Gene3D G3DSA:1.10.3810.10 79 279 1.7E-75 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CDW54_RS04385 1628a19170cc836ef0783ea645271e8f 723 SUPERFAMILY SSF56601 244 266 1.5E-101 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CDW54_RS04385 1628a19170cc836ef0783ea645271e8f 723 SUPERFAMILY SSF56601 299 651 1.5E-101 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CDW54_RS04385 1628a19170cc836ef0783ea645271e8f 723 Gene3D G3DSA:3.40.710.10 293 644 4.3E-95 T 28-03-2018 CDW54_RS04385 1628a19170cc836ef0783ea645271e8f 723 Pfam PF00912 Transglycosylase 91 262 3.8E-62 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CDW54_RS04385 1628a19170cc836ef0783ea645271e8f 723 SUPERFAMILY SSF53955 76 284 7.31E-71 T 28-03-2018 IPR023346 Lysozyme-like domain CDW54_RS04385 1628a19170cc836ef0783ea645271e8f 723 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 98 638 1.3E-181 T 28-03-2018 CDW54_RS01910 1d7bf1e46fc6432364642c714a13d7c0 254 Hamap MF_01974 Methionine aminopeptidase [map]. 2 248 37.44 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CDW54_RS01910 1d7bf1e46fc6432364642c714a13d7c0 254 Gene3D G3DSA:3.90.230.10 1 253 1.1E-77 T 28-03-2018 CDW54_RS01910 1d7bf1e46fc6432364642c714a13d7c0 254 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 247 2.5E-85 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CDW54_RS01910 1d7bf1e46fc6432364642c714a13d7c0 254 Pfam PF00557 Metallopeptidase family M24 11 239 5.2E-49 T 28-03-2018 IPR000994 Peptidase M24 CDW54_RS01910 1d7bf1e46fc6432364642c714a13d7c0 254 SUPERFAMILY SSF55920 1 247 1.44E-80 T 28-03-2018 IPR000994 Peptidase M24 CDW54_RS01910 1d7bf1e46fc6432364642c714a13d7c0 254 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 165 183 - T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CDW54_RS01910 1d7bf1e46fc6432364642c714a13d7c0 254 PRINTS PR00599 Methionine aminopeptidase-1 signature 190 202 1.9E-17 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CDW54_RS01910 1d7bf1e46fc6432364642c714a13d7c0 254 PRINTS PR00599 Methionine aminopeptidase-1 signature 159 171 1.9E-17 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CDW54_RS01910 1d7bf1e46fc6432364642c714a13d7c0 254 PRINTS PR00599 Methionine aminopeptidase-1 signature 67 80 1.9E-17 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CDW54_RS01910 1d7bf1e46fc6432364642c714a13d7c0 254 PRINTS PR00599 Methionine aminopeptidase-1 signature 89 105 1.9E-17 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CDW54_RS04995 957b7756043fac422a4bbe326295da90 283 PIRSF PIRSF010376 1 283 5.9E-94 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CDW54_RS04995 957b7756043fac422a4bbe326295da90 283 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 2 282 2.4E-90 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CDW54_RS04995 957b7756043fac422a4bbe326295da90 283 SUPERFAMILY SSF54211 3 156 1.06E-44 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CDW54_RS04995 957b7756043fac422a4bbe326295da90 283 Pfam PF08544 GHMP kinases C terminal 198 270 9.4E-11 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CDW54_RS04995 957b7756043fac422a4bbe326295da90 283 Gene3D G3DSA:3.30.70.890 160 283 1.5E-28 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CDW54_RS04995 957b7756043fac422a4bbe326295da90 283 Pfam PF00288 GHMP kinases N terminal domain 86 144 1.2E-11 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CDW54_RS04995 957b7756043fac422a4bbe326295da90 283 SUPERFAMILY SSF55060 162 281 4.68E-33 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CDW54_RS04995 957b7756043fac422a4bbe326295da90 283 Gene3D G3DSA:3.30.230.10 4 159 3.4E-43 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CDW54_RS04995 957b7756043fac422a4bbe326295da90 283 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 3 279 34.839 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CDW54_RS06740 013ec76c27a7e1b0fc3e067ec8239783 314 Pfam PF00288 GHMP kinases N terminal domain 89 150 9.4E-15 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CDW54_RS06740 013ec76c27a7e1b0fc3e067ec8239783 314 PRINTS PR00959 Mevalonate kinase family signature 93 115 5.4E-20 T 28-03-2018 CDW54_RS06740 013ec76c27a7e1b0fc3e067ec8239783 314 PRINTS PR00959 Mevalonate kinase family signature 9 33 5.4E-20 T 28-03-2018 CDW54_RS06740 013ec76c27a7e1b0fc3e067ec8239783 314 PRINTS PR00959 Mevalonate kinase family signature 136 155 5.4E-20 T 28-03-2018 CDW54_RS06740 013ec76c27a7e1b0fc3e067ec8239783 314 PRINTS PR00959 Mevalonate kinase family signature 266 283 5.4E-20 T 28-03-2018 CDW54_RS06740 013ec76c27a7e1b0fc3e067ec8239783 314 Gene3D G3DSA:3.30.230.10 6 40 1.1E-4 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CDW54_RS06740 013ec76c27a7e1b0fc3e067ec8239783 314 Gene3D G3DSA:3.30.230.10 41 181 1.6E-24 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CDW54_RS06740 013ec76c27a7e1b0fc3e067ec8239783 314 Pfam PF08544 GHMP kinases C terminal 220 298 1.5E-11 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CDW54_RS06740 013ec76c27a7e1b0fc3e067ec8239783 314 SUPERFAMILY SSF55060 172 306 2.88E-32 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CDW54_RS06740 013ec76c27a7e1b0fc3e067ec8239783 314 Gene3D G3DSA:3.30.70.890 182 309 2.8E-27 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CDW54_RS06740 013ec76c27a7e1b0fc3e067ec8239783 314 SUPERFAMILY SSF54211 9 187 4.86E-34 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CDW54_RS06740 013ec76c27a7e1b0fc3e067ec8239783 314 TIGRFAM TIGR00549 mevalon_kin: mevalonate kinase 10 281 3.0E-81 T 28-03-2018 IPR006205 Mevalonate kinase GO:0004496|GO:0005524|GO:0005737|GO:0008299 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168 CDW54_RS11535 67714c4dd25ca472840b0dfcf7cf85a3 47 SUPERFAMILY SSF56349 2 38 9.42E-5 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CDW54_RS11535 67714c4dd25ca472840b0dfcf7cf85a3 47 Gene3D G3DSA:1.10.443.10 2 45 3.1E-5 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CDW54_RS12630 4e2c4294919d3dfc57bc6d62f65a84f7 262 SUPERFAMILY SSF51735 1 250 4.93E-66 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS12630 4e2c4294919d3dfc57bc6d62f65a84f7 262 Gene3D G3DSA:3.40.50.720 1 261 3.7E-55 T 28-03-2018 CDW54_RS12630 4e2c4294919d3dfc57bc6d62f65a84f7 262 Pfam PF00106 short chain dehydrogenase 6 196 7.7E-57 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS12630 4e2c4294919d3dfc57bc6d62f65a84f7 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 5.1E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS12630 4e2c4294919d3dfc57bc6d62f65a84f7 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 5.1E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS12630 4e2c4294919d3dfc57bc6d62f65a84f7 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 5.1E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS12630 4e2c4294919d3dfc57bc6d62f65a84f7 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 5.1E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS12630 4e2c4294919d3dfc57bc6d62f65a84f7 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 5.1E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS12630 4e2c4294919d3dfc57bc6d62f65a84f7 262 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CDW54_RS12630 4e2c4294919d3dfc57bc6d62f65a84f7 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 5.0E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS12630 4e2c4294919d3dfc57bc6d62f65a84f7 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 5.0E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS12630 4e2c4294919d3dfc57bc6d62f65a84f7 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 5.0E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS04470 e784f4aca4007c0347bc7fe015d1ce94 196 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 10 187 7.3E-32 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT CDW54_RS06720 af24499d0c6dd067ddd90c9a3eee32fe 267 Gene3D G3DSA:3.40.50.720 5 48 6.3E-9 T 28-03-2018 CDW54_RS06720 af24499d0c6dd067ddd90c9a3eee32fe 267 Gene3D G3DSA:3.40.50.720 49 266 9.0E-58 T 28-03-2018 CDW54_RS06720 af24499d0c6dd067ddd90c9a3eee32fe 267 SUPERFAMILY SSF51735 7 261 1.21E-77 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS06720 af24499d0c6dd067ddd90c9a3eee32fe 267 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CDW54_RS06720 af24499d0c6dd067ddd90c9a3eee32fe 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 2.2E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS06720 af24499d0c6dd067ddd90c9a3eee32fe 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 2.2E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS06720 af24499d0c6dd067ddd90c9a3eee32fe 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 2.2E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS06720 af24499d0c6dd067ddd90c9a3eee32fe 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 2.2E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS06720 af24499d0c6dd067ddd90c9a3eee32fe 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 2.2E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS06720 af24499d0c6dd067ddd90c9a3eee32fe 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 2.2E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS06720 af24499d0c6dd067ddd90c9a3eee32fe 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 1.2E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS06720 af24499d0c6dd067ddd90c9a3eee32fe 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 1.2E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS06720 af24499d0c6dd067ddd90c9a3eee32fe 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 1.2E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS06720 af24499d0c6dd067ddd90c9a3eee32fe 267 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 259 1.4E-62 T 28-03-2018 CDW54_RS06755 a4dcce5c59d10f1c026c56421f798bc7 210 SUPERFAMILY SSF141571 35 208 1.14E-33 T 28-03-2018 CDW54_RS06755 a4dcce5c59d10f1c026c56421f798bc7 210 Pfam PF13599 Pentapeptide repeats (9 copies) 86 172 2.1E-20 T 28-03-2018 IPR001646 Pentapeptide repeat CDW54_RS06755 a4dcce5c59d10f1c026c56421f798bc7 210 Gene3D G3DSA:2.160.20.80 22 210 2.0E-26 T 28-03-2018 CDW54_RS01010 40a2ad7474b456d9df3846a49c13fd8b 369 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 132 368 1.3E-125 T 28-03-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 CDW54_RS01010 40a2ad7474b456d9df3846a49c13fd8b 369 SUPERFAMILY SSF88946 97 206 3.79E-55 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDW54_RS01010 40a2ad7474b456d9df3846a49c13fd8b 369 Pfam PF03979 Sigma-70 factor, region 1.1 9 86 4.8E-13 T 28-03-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 CDW54_RS01010 40a2ad7474b456d9df3846a49c13fd8b 369 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 9 369 34.409 T 28-03-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 CDW54_RS01010 40a2ad7474b456d9df3846a49c13fd8b 369 Pfam PF04542 Sigma-70 region 2 136 205 1.5E-22 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDW54_RS01010 40a2ad7474b456d9df3846a49c13fd8b 369 PRINTS PR00046 Major sigma-70 factor signature 160 173 2.7E-32 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDW54_RS01010 40a2ad7474b456d9df3846a49c13fd8b 369 PRINTS PR00046 Major sigma-70 factor signature 308 320 2.7E-32 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDW54_RS01010 40a2ad7474b456d9df3846a49c13fd8b 369 PRINTS PR00046 Major sigma-70 factor signature 329 344 2.7E-32 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDW54_RS01010 40a2ad7474b456d9df3846a49c13fd8b 369 PRINTS PR00046 Major sigma-70 factor signature 184 192 2.7E-32 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDW54_RS01010 40a2ad7474b456d9df3846a49c13fd8b 369 PRINTS PR00046 Major sigma-70 factor signature 344 355 2.7E-32 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDW54_RS01010 40a2ad7474b456d9df3846a49c13fd8b 369 Pfam PF04545 Sigma-70, region 4 304 357 5.1E-20 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDW54_RS01010 40a2ad7474b456d9df3846a49c13fd8b 369 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 132 357 5.7E-40 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDW54_RS01010 40a2ad7474b456d9df3846a49c13fd8b 369 Pfam PF00140 Sigma-70 factor, region 1.2 98 131 3.7E-17 T 28-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDW54_RS01010 40a2ad7474b456d9df3846a49c13fd8b 369 SUPERFAMILY SSF88659 209 282 9.53E-23 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDW54_RS01010 40a2ad7474b456d9df3846a49c13fd8b 369 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 329 355 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDW54_RS01010 40a2ad7474b456d9df3846a49c13fd8b 369 Gene3D G3DSA:1.10.601.10 2 205 9.9E-78 T 28-03-2018 CDW54_RS01010 40a2ad7474b456d9df3846a49c13fd8b 369 Gene3D G3DSA:1.10.10.10 298 369 3.5E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS01010 40a2ad7474b456d9df3846a49c13fd8b 369 Gene3D G3DSA:1.10.10.10 206 256 2.3E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS01010 40a2ad7474b456d9df3846a49c13fd8b 369 Pfam PF04539 Sigma-70 region 3 215 291 1.3E-31 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDW54_RS01010 40a2ad7474b456d9df3846a49c13fd8b 369 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 160 173 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDW54_RS01010 40a2ad7474b456d9df3846a49c13fd8b 369 SUPERFAMILY SSF88659 266 367 5.23E-30 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDW54_RS00700 c8dd2c96621bb60f1eb13693ee8e9d30 308 SMART SM01131 181 307 2.3E-58 T 28-03-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CDW54_RS00700 c8dd2c96621bb60f1eb13693ee8e9d30 308 Pfam PF02833 DHHA2 domain 183 305 8.5E-22 T 28-03-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CDW54_RS00700 c8dd2c96621bb60f1eb13693ee8e9d30 308 SUPERFAMILY SSF64182 2 305 1.83E-84 T 28-03-2018 CDW54_RS00700 c8dd2c96621bb60f1eb13693ee8e9d30 308 Hamap MF_00207 Probable manganese-dependent inorganic pyrophosphatase [ppaC]. 3 308 44.082 T 28-03-2018 IPR022934 Manganese-dependent inorganic pyrophosphatase, probable GO:0004427 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CDW54_RS00700 c8dd2c96621bb60f1eb13693ee8e9d30 308 Pfam PF01368 DHH family 3 146 2.8E-29 T 28-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CDW54_RS00700 c8dd2c96621bb60f1eb13693ee8e9d30 308 Gene3D G3DSA:3.90.1640.10 1 188 4.5E-68 T 28-03-2018 CDW54_RS02075 b9a4c85eb3edc00f1b348658051f89d3 730 Pfam PF00905 Penicillin binding protein transpeptidase domain 289 597 1.7E-80 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CDW54_RS02075 b9a4c85eb3edc00f1b348658051f89d3 730 Gene3D G3DSA:3.40.710.10 263 627 3.9E-72 T 28-03-2018 CDW54_RS02075 b9a4c85eb3edc00f1b348658051f89d3 730 Pfam PF03717 Penicillin-binding Protein dimerisation domain 73 242 2.1E-25 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CDW54_RS02075 b9a4c85eb3edc00f1b348658051f89d3 730 Gene3D G3DSA:3.90.1310.10 38 261 5.6E-33 T 28-03-2018 CDW54_RS02075 b9a4c85eb3edc00f1b348658051f89d3 730 SUPERFAMILY SSF56601 213 605 6.66E-86 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CDW54_RS02075 b9a4c85eb3edc00f1b348658051f89d3 730 SMART SM00740 614 674 1.5E-6 T 28-03-2018 IPR005543 PASTA domain CDW54_RS02075 b9a4c85eb3edc00f1b348658051f89d3 730 SMART SM00740 675 730 5.7E-6 T 28-03-2018 IPR005543 PASTA domain CDW54_RS02075 b9a4c85eb3edc00f1b348658051f89d3 730 SUPERFAMILY SSF56519 70 262 4.58E-42 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CDW54_RS02075 b9a4c85eb3edc00f1b348658051f89d3 730 Pfam PF03793 PASTA domain 678 724 3.7E-5 T 28-03-2018 IPR005543 PASTA domain CDW54_RS02075 b9a4c85eb3edc00f1b348658051f89d3 730 SUPERFAMILY SSF54184 677 723 3.27E-9 T 28-03-2018 CDW54_RS02075 b9a4c85eb3edc00f1b348658051f89d3 730 SUPERFAMILY SSF54184 615 674 1.83E-10 T 28-03-2018 CDW54_RS10115 92c2957976c1001789bea3629865917b 152 SUPERFAMILY SSF55804 3 146 2.62E-37 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CDW54_RS10115 92c2957976c1001789bea3629865917b 152 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 3 146 2.1E-38 T 28-03-2018 IPR002178 PTS EIIA type-2 domain CDW54_RS10115 92c2957976c1001789bea3629865917b 152 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 4 131 8.5E-42 T 28-03-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 CDW54_RS10115 92c2957976c1001789bea3629865917b 152 Gene3D G3DSA:3.40.930.10 1 148 2.2E-37 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CDW54_RS11360 6f10767feb139a4dd486f460820f902b 207 SUPERFAMILY SSF56784 1 200 2.44E-38 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS11360 6f10767feb139a4dd486f460820f902b 207 Gene3D G3DSA:3.40.50.1000 67 207 8.3E-24 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS11360 6f10767feb139a4dd486f460820f902b 207 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 175 2.0E-31 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS11360 6f10767feb139a4dd486f460820f902b 207 Gene3D G3DSA:1.10.150.240 14 66 2.0E-19 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CDW54_RS11360 6f10767feb139a4dd486f460820f902b 207 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 4 171 8.0E-10 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDW54_RS06130 09486e59cd17de24bb86c78e0ecb2d58 62 Pfam PF00830 Ribosomal L28 family 3 58 3.3E-22 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS06130 09486e59cd17de24bb86c78e0ecb2d58 62 Gene3D G3DSA:2.30.170.40 2 62 7.8E-21 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS06130 09486e59cd17de24bb86c78e0ecb2d58 62 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 62 18.777 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS06130 09486e59cd17de24bb86c78e0ecb2d58 62 SUPERFAMILY SSF143800 1 60 9.42E-25 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS06130 09486e59cd17de24bb86c78e0ecb2d58 62 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 56 2.7E-22 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS09130 d04ce5bb091f28ce740f25b8398e366e 504 SUPERFAMILY SSF51905 441 502 2.71E-61 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS09130 d04ce5bb091f28ce740f25b8398e366e 504 SUPERFAMILY SSF51905 48 313 2.71E-61 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS09130 d04ce5bb091f28ce740f25b8398e366e 504 SUPERFAMILY SSF56425 291 437 6.28E-45 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CDW54_RS09130 d04ce5bb091f28ce740f25b8398e366e 504 Gene3D G3DSA:3.90.700.10 321 433 1.9E-33 T 28-03-2018 CDW54_RS09130 d04ce5bb091f28ce740f25b8398e366e 504 TIGRFAM TIGR01813 flavo_cyto_c: flavocytochrome c 60 493 2.0E-164 T 28-03-2018 IPR010960 Flavocytochrome c GO:0000104|GO:0055114 CDW54_RS09130 d04ce5bb091f28ce740f25b8398e366e 504 Pfam PF00890 FAD binding domain 60 482 4.6E-95 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CDW54_RS09130 d04ce5bb091f28ce740f25b8398e366e 504 Gene3D G3DSA:3.50.50.60 42 320 3.3E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS09130 d04ce5bb091f28ce740f25b8398e366e 504 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 446 468 5.1E-6 T 28-03-2018 CDW54_RS09130 d04ce5bb091f28ce740f25b8398e366e 504 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 61 80 5.1E-6 T 28-03-2018 CDW54_RS00785 96dd765c0398b5091e85e3d9ae7b7250 286 Gene3D G3DSA:1.10.1580.10 180 269 1.7E-17 T 28-03-2018 IPR023179 GTP-binding protein, orthogonal bundle domain CDW54_RS00785 96dd765c0398b5091e85e3d9ae7b7250 286 TIGRFAM TIGR03596 GTPase_YlqF: ribosome biogenesis GTP-binding protein YlqF 3 275 6.4E-110 T 28-03-2018 IPR019991 GTP-binding protein, ribosome biogenesis CDW54_RS00785 96dd765c0398b5091e85e3d9ae7b7250 286 Pfam PF01926 50S ribosome-binding GTPase 123 204 8.3E-17 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CDW54_RS00785 96dd765c0398b5091e85e3d9ae7b7250 286 Gene3D G3DSA:3.40.50.300 12 179 9.4E-33 T 28-03-2018 CDW54_RS00785 96dd765c0398b5091e85e3d9ae7b7250 286 PIRSF PIRSF006230 1 280 1.5E-98 T 28-03-2018 IPR016478 GTPase, MTG1 CDW54_RS00785 96dd765c0398b5091e85e3d9ae7b7250 286 SUPERFAMILY SSF52540 9 195 2.63E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS00785 96dd765c0398b5091e85e3d9ae7b7250 286 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 123 143 7.7E-5 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CDW54_RS00785 96dd765c0398b5091e85e3d9ae7b7250 286 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 169 184 7.7E-5 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CDW54_RS03835 42013b76c80a78b849726ccec927321b 229 SUPERFAMILY SSF56808 6 225 1.11E-86 T 28-03-2018 IPR023674 Ribosomal protein L1-like CDW54_RS03835 42013b76c80a78b849726ccec927321b 229 PIRSF PIRSF002155 1 227 2.0E-82 T 28-03-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS03835 42013b76c80a78b849726ccec927321b 229 Pfam PF00687 Ribosomal protein L1p/L10e family 33 220 1.1E-55 T 28-03-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein CDW54_RS03835 42013b76c80a78b849726ccec927321b 229 Gene3D G3DSA:3.40.50.790 68 144 8.3E-39 T 28-03-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich CDW54_RS03835 42013b76c80a78b849726ccec927321b 229 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 28-03-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS03835 42013b76c80a78b849726ccec927321b 229 Gene3D G3DSA:3.30.190.20 145 224 2.6E-19 T 28-03-2018 CDW54_RS03835 42013b76c80a78b849726ccec927321b 229 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 44.702 T 28-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 CDW54_RS03835 42013b76c80a78b849726ccec927321b 229 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 228 5.7E-106 T 28-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 CDW54_RS06665 cec5e69bca443bc855f5bf514c26fb30 343 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 3 342 3.6E-140 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CDW54_RS06665 cec5e69bca443bc855f5bf514c26fb30 343 Gene3D G3DSA:3.40.1780.10 174 342 2.7E-65 T 28-03-2018 CDW54_RS06665 cec5e69bca443bc855f5bf514c26fb30 343 Gene3D G3DSA:3.40.1780.10 1 145 8.2E-43 T 28-03-2018 CDW54_RS06665 cec5e69bca443bc855f5bf514c26fb30 343 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 2 343 46.634 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CDW54_RS06665 cec5e69bca443bc855f5bf514c26fb30 343 SUPERFAMILY SSF111337 3 342 3.53E-138 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CDW54_RS06665 cec5e69bca443bc855f5bf514c26fb30 343 Pfam PF02547 Queuosine biosynthesis protein 5 342 9.1E-141 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CDW54_RS10995 0716d02b74399a8683f1255f3cf6954a 388 ProSitePatterns PS00636 Nt-dnaJ domain signature. 47 66 - T 28-03-2018 IPR018253 DnaJ domain, conserved site CDW54_RS10995 0716d02b74399a8683f1255f3cf6954a 388 Pfam PF00684 DnaJ central domain 154 218 1.9E-13 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CDW54_RS10995 0716d02b74399a8683f1255f3cf6954a 388 Pfam PF00226 DnaJ domain 6 67 5.8E-29 T 28-03-2018 IPR001623 DnaJ domain CDW54_RS10995 0716d02b74399a8683f1255f3cf6954a 388 SUPERFAMILY SSF46565 2 108 8.24E-39 T 28-03-2018 IPR001623 DnaJ domain CDW54_RS10995 0716d02b74399a8683f1255f3cf6954a 388 SUPERFAMILY SSF49493 121 145 5.49E-20 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CDW54_RS10995 0716d02b74399a8683f1255f3cf6954a 388 SUPERFAMILY SSF49493 211 277 5.49E-20 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CDW54_RS10995 0716d02b74399a8683f1255f3cf6954a 388 Gene3D G3DSA:2.60.260.20 120 187 3.4E-14 T 28-03-2018 CDW54_RS10995 0716d02b74399a8683f1255f3cf6954a 388 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 6 361 7.5E-143 T 28-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CDW54_RS10995 0716d02b74399a8683f1255f3cf6954a 388 Pfam PF01556 DnaJ C terminal domain 127 344 4.8E-41 T 28-03-2018 IPR002939 Chaperone DnaJ, C-terminal CDW54_RS10995 0716d02b74399a8683f1255f3cf6954a 388 Gene3D G3DSA:1.10.287.110 2 119 2.2E-38 T 28-03-2018 IPR001623 DnaJ domain CDW54_RS10995 0716d02b74399a8683f1255f3cf6954a 388 Gene3D G3DSA:2.60.260.20 266 376 1.4E-27 T 28-03-2018 CDW54_RS10995 0716d02b74399a8683f1255f3cf6954a 388 PRINTS PR00625 DnaJ domain signature 26 41 1.1E-33 T 28-03-2018 IPR001623 DnaJ domain CDW54_RS10995 0716d02b74399a8683f1255f3cf6954a 388 PRINTS PR00625 DnaJ domain signature 42 62 1.1E-33 T 28-03-2018 IPR001623 DnaJ domain CDW54_RS10995 0716d02b74399a8683f1255f3cf6954a 388 PRINTS PR00625 DnaJ domain signature 62 81 1.1E-33 T 28-03-2018 IPR001623 DnaJ domain CDW54_RS10995 0716d02b74399a8683f1255f3cf6954a 388 PRINTS PR00625 DnaJ domain signature 8 26 1.1E-33 T 28-03-2018 IPR001623 DnaJ domain CDW54_RS10995 0716d02b74399a8683f1255f3cf6954a 388 SUPERFAMILY SSF57938 141 221 1.44E-19 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CDW54_RS10995 0716d02b74399a8683f1255f3cf6954a 388 SMART SM00271 5 62 2.0E-33 T 28-03-2018 IPR001623 DnaJ domain CDW54_RS10995 0716d02b74399a8683f1255f3cf6954a 388 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 3 381 41.87 T 28-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CDW54_RS10995 0716d02b74399a8683f1255f3cf6954a 388 Gene3D G3DSA:2.60.260.20 188 265 3.0E-19 T 28-03-2018 CDW54_RS10995 0716d02b74399a8683f1255f3cf6954a 388 SUPERFAMILY SSF49493 270 355 5.36E-23 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CDW54_RS06180 be73b5894c14d20ceabca60de1713b88 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 295 2.9E-28 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS06180 be73b5894c14d20ceabca60de1713b88 304 SUPERFAMILY SSF161098 93 285 1.44E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS06180 be73b5894c14d20ceabca60de1713b88 304 Gene3D G3DSA:1.10.3720.10 20 291 9.7E-38 T 28-03-2018 CDW54_RS06180 be73b5894c14d20ceabca60de1713b88 304 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 21 69 1.5E-5 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CDW54_RS10870 10f61055c4ad1ade31540cf56ec06b75 391 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 389 29.745 T 28-03-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 CDW54_RS10870 10f61055c4ad1ade31540cf56ec06b75 391 Pfam PF00575 S1 RNA binding domain 135 193 9.4E-6 T 28-03-2018 IPR003029 S1 domain GO:0003676 CDW54_RS10870 10f61055c4ad1ade31540cf56ec06b75 391 SUPERFAMILY SSF50249 133 198 2.98E-17 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDW54_RS10870 10f61055c4ad1ade31540cf56ec06b75 391 Gene3D G3DSA:3.30.1480.10 1 129 4.6E-52 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CDW54_RS10870 10f61055c4ad1ade31540cf56ec06b75 391 SUPERFAMILY SSF54814 278 343 9.16E-16 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CDW54_RS10870 10f61055c4ad1ade31540cf56ec06b75 391 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 4 342 8.9E-132 T 28-03-2018 IPR010213 Transcription termination factor NusA GO:0003723 CDW54_RS10870 10f61055c4ad1ade31540cf56ec06b75 391 Gene3D G3DSA:2.40.50.140 136 197 6.5E-12 T 28-03-2018 CDW54_RS10870 10f61055c4ad1ade31540cf56ec06b75 391 SMART SM00322 302 366 4.3 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CDW54_RS10870 10f61055c4ad1ade31540cf56ec06b75 391 SMART SM00322 229 301 0.09 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CDW54_RS10870 10f61055c4ad1ade31540cf56ec06b75 391 Gene3D G3DSA:3.30.300.20 198 272 1.1E-35 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CDW54_RS10870 10f61055c4ad1ade31540cf56ec06b75 391 SMART SM00316 133 199 1.6E-7 T 28-03-2018 IPR022967 RNA-binding domain, S1 CDW54_RS10870 10f61055c4ad1ade31540cf56ec06b75 391 SUPERFAMILY SSF54814 199 277 2.03E-30 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CDW54_RS10870 10f61055c4ad1ade31540cf56ec06b75 391 Pfam PF08529 NusA N-terminal domain 4 123 3.7E-44 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CDW54_RS10870 10f61055c4ad1ade31540cf56ec06b75 391 Gene3D G3DSA:3.30.300.20 273 342 8.4E-15 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CDW54_RS10870 10f61055c4ad1ade31540cf56ec06b75 391 SUPERFAMILY SSF69705 1 126 1.02E-44 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CDW54_RS10870 10f61055c4ad1ade31540cf56ec06b75 391 Pfam PF13184 NusA-like KH domain 229 296 1.4E-30 T 28-03-2018 IPR025249 KH domain, NusA-like GO:0003723 CDW54_RS03990 57b0901857af1942dc9bc9ba01998f8f 217 PIRSF PIRSF029008 1 217 1.8E-60 T 28-03-2018 IPR008681 Negative regulator of genetic competence, MecA CDW54_RS03990 57b0901857af1942dc9bc9ba01998f8f 217 Hamap MF_01124 Adapter protein MecA [mecA]. 1 216 23.337 T 28-03-2018 IPR008681 Negative regulator of genetic competence, MecA CDW54_RS03990 57b0901857af1942dc9bc9ba01998f8f 217 Pfam PF05389 Negative regulator of genetic competence (MecA) 1 211 1.9E-46 T 28-03-2018 IPR008681 Negative regulator of genetic competence, MecA CDW54_RS03340 da502a04d8a3b2e7b62c2bc36d6acc44 414 Pfam PF00464 Serine hydroxymethyltransferase 6 381 1.7E-176 T 28-03-2018 CDW54_RS03340 da502a04d8a3b2e7b62c2bc36d6acc44 414 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 3 413 53.771 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CDW54_RS03340 da502a04d8a3b2e7b62c2bc36d6acc44 414 PIRSF PIRSF000412 2 413 1.2E-166 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CDW54_RS03340 da502a04d8a3b2e7b62c2bc36d6acc44 414 SUPERFAMILY SSF53383 4 412 9.39E-178 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDW54_RS03340 da502a04d8a3b2e7b62c2bc36d6acc44 414 Gene3D G3DSA:3.40.640.10 33 269 6.2E-51 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDW54_RS03340 da502a04d8a3b2e7b62c2bc36d6acc44 414 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 218 234 - T 28-03-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CDW54_RS03340 da502a04d8a3b2e7b62c2bc36d6acc44 414 Gene3D G3DSA:3.90.1150.10 270 412 4.3E-57 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDW54_RS09955 bdbb27a1d6ec6e39675eb70a7b61fb93 575 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 486 564 2.6E-10 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDW54_RS09955 bdbb27a1d6ec6e39675eb70a7b61fb93 575 Gene3D G3DSA:3.40.120.10 339 457 9.3E-39 T 28-03-2018 CDW54_RS09955 bdbb27a1d6ec6e39675eb70a7b61fb93 575 Gene3D G3DSA:3.30.310.50 469 575 4.2E-25 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDW54_RS09955 bdbb27a1d6ec6e39675eb70a7b61fb93 575 SUPERFAMILY SSF53738 306 456 1.37E-32 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDW54_RS09955 bdbb27a1d6ec6e39675eb70a7b61fb93 575 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 139 153 3.3E-5 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDW54_RS09955 bdbb27a1d6ec6e39675eb70a7b61fb93 575 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 298 313 3.3E-5 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDW54_RS09955 bdbb27a1d6ec6e39675eb70a7b61fb93 575 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 43 180 3.2E-38 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDW54_RS09955 bdbb27a1d6ec6e39675eb70a7b61fb93 575 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 140 149 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDW54_RS09955 bdbb27a1d6ec6e39675eb70a7b61fb93 575 SUPERFAMILY SSF53738 31 238 4.47E-46 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDW54_RS09955 bdbb27a1d6ec6e39675eb70a7b61fb93 575 Gene3D G3DSA:3.40.120.10 214 338 3.7E-29 T 28-03-2018 CDW54_RS09955 bdbb27a1d6ec6e39675eb70a7b61fb93 575 Gene3D G3DSA:3.40.120.10 13 213 4.0E-53 T 28-03-2018 CDW54_RS09955 bdbb27a1d6ec6e39675eb70a7b61fb93 575 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 326 453 1.4E-22 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDW54_RS09955 bdbb27a1d6ec6e39675eb70a7b61fb93 575 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 210 314 8.0E-24 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDW54_RS09955 bdbb27a1d6ec6e39675eb70a7b61fb93 575 SUPERFAMILY SSF53738 210 314 9.03E-20 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDW54_RS09955 bdbb27a1d6ec6e39675eb70a7b61fb93 575 SUPERFAMILY SSF55957 446 483 2.88E-15 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDW54_RS09955 bdbb27a1d6ec6e39675eb70a7b61fb93 575 SUPERFAMILY SSF55957 514 573 2.88E-15 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDW54_RS07390 79364bfc54ef537d7058112ba8f4d9da 607 Gene3D G3DSA:3.30.9.10 220 349 3.4E-38 T 28-03-2018 CDW54_RS07390 79364bfc54ef537d7058112ba8f4d9da 607 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 24 41 - T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CDW54_RS07390 79364bfc54ef537d7058112ba8f4d9da 607 Gene3D G3DSA:3.50.50.60 4 219 1.1E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS07390 79364bfc54ef537d7058112ba8f4d9da 607 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 462 584 3.3E-15 T 28-03-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CDW54_RS07390 79364bfc54ef537d7058112ba8f4d9da 607 SUPERFAMILY SSF54373 252 348 1.83E-11 T 28-03-2018 CDW54_RS07390 79364bfc54ef537d7058112ba8f4d9da 607 Pfam PF01266 FAD dependent oxidoreductase 20 348 2.6E-52 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CDW54_RS07390 79364bfc54ef537d7058112ba8f4d9da 607 SUPERFAMILY SSF51905 160 243 8.29E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS07390 79364bfc54ef537d7058112ba8f4d9da 607 SUPERFAMILY SSF51905 5 96 8.29E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS07390 79364bfc54ef537d7058112ba8f4d9da 607 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 93 105 6.2E-29 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CDW54_RS07390 79364bfc54ef537d7058112ba8f4d9da 607 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 342 348 6.2E-29 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CDW54_RS07390 79364bfc54ef537d7058112ba8f4d9da 607 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 48 60 6.2E-29 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CDW54_RS07390 79364bfc54ef537d7058112ba8f4d9da 607 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 19 31 6.2E-29 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CDW54_RS07390 79364bfc54ef537d7058112ba8f4d9da 607 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 422 434 6.2E-29 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CDW54_RS07390 79364bfc54ef537d7058112ba8f4d9da 607 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 32 42 6.2E-29 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CDW54_RS01015 c84f376f879f1f53789e3ca529a7408e 613 Pfam PF08275 DNA primase catalytic core, N-terminal domain 129 261 1.7E-41 T 28-03-2018 IPR013264 DNA primase, catalytic core, N-terminal CDW54_RS01015 c84f376f879f1f53789e3ca529a7408e 613 SUPERFAMILY SSF56731 118 431 1.46E-96 T 28-03-2018 CDW54_RS01015 c84f376f879f1f53789e3ca529a7408e 613 Pfam PF01807 CHC2 zinc finger 6 99 6.4E-38 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CDW54_RS01015 c84f376f879f1f53789e3ca529a7408e 613 SMART SM00400 36 90 1.1E-33 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CDW54_RS01015 c84f376f879f1f53789e3ca529a7408e 613 SUPERFAMILY SSF57783 4 98 1.6E-36 T 28-03-2018 CDW54_RS01015 c84f376f879f1f53789e3ca529a7408e 613 SMART SM00493 268 339 3.5E-9 T 28-03-2018 IPR006171 TOPRIM domain CDW54_RS01015 c84f376f879f1f53789e3ca529a7408e 613 Gene3D G3DSA:3.40.1360.10 250 373 4.9E-31 T 28-03-2018 CDW54_RS01015 c84f376f879f1f53789e3ca529a7408e 613 Hamap MF_00974 DNA primase [dnaG]. 4 600 28.251 T 28-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 CDW54_RS01015 c84f376f879f1f53789e3ca529a7408e 613 TIGRFAM TIGR01391 dnaG: DNA primase 4 426 6.4E-148 T 28-03-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 CDW54_RS01015 c84f376f879f1f53789e3ca529a7408e 613 Pfam PF10410 DnaB-helicase binding domain of primase 377 432 2.8E-10 T 28-03-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 CDW54_RS01015 c84f376f879f1f53789e3ca529a7408e 613 PIRSF PIRSF002811 2 610 1.4E-187 T 28-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 CDW54_RS01015 c84f376f879f1f53789e3ca529a7408e 613 Pfam PF13155 Toprim-like 272 357 1.4E-17 T 28-03-2018 CDW54_RS01015 c84f376f879f1f53789e3ca529a7408e 613 Gene3D G3DSA:3.90.980.10 111 249 3.5E-41 T 28-03-2018 IPR013264 DNA primase, catalytic core, N-terminal CDW54_RS01015 c84f376f879f1f53789e3ca529a7408e 613 Gene3D G3DSA:3.90.580.10 1 101 2.9E-36 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CDW54_RS05610 ad9ada7a76c7b08ee475dff85b482445 111 SUPERFAMILY SSF47413 5 68 2.09E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDW54_RS05610 ad9ada7a76c7b08ee475dff85b482445 111 SMART SM00530 9 64 1.6E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDW54_RS05610 ad9ada7a76c7b08ee475dff85b482445 111 Pfam PF01381 Helix-turn-helix 10 62 1.8E-16 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDW54_RS05610 ad9ada7a76c7b08ee475dff85b482445 111 Gene3D G3DSA:1.10.260.40 1 109 4.4E-22 T 28-03-2018 CDW54_RS08045 884b58470b9634d9f9c369260a690be7 457 Gene3D G3DSA:1.20.1250.20 1 195 2.6E-25 T 28-03-2018 CDW54_RS08045 884b58470b9634d9f9c369260a690be7 457 SUPERFAMILY SSF103473 9 195 2.49E-56 T 28-03-2018 IPR020846 Major facilitator superfamily domain CDW54_RS08045 884b58470b9634d9f9c369260a690be7 457 SUPERFAMILY SSF103473 241 445 2.49E-56 T 28-03-2018 IPR020846 Major facilitator superfamily domain CDW54_RS08045 884b58470b9634d9f9c369260a690be7 457 Pfam PF07690 Major Facilitator Superfamily 20 402 4.4E-41 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDW54_RS08045 884b58470b9634d9f9c369260a690be7 457 Gene3D G3DSA:1.20.1250.20 252 456 6.8E-26 T 28-03-2018 CDW54_RS11040 46c90bd68cffabbb45846af73a641ed0 311 Pfam PF14527 WhiA LAGLIDADG-like domain 124 216 2.6E-34 T 28-03-2018 CDW54_RS11040 46c90bd68cffabbb45846af73a641ed0 311 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 3 306 34.8 T 28-03-2018 IPR003802 Sporulation regulator WhiA GO:0043937 CDW54_RS11040 46c90bd68cffabbb45846af73a641ed0 311 SUPERFAMILY SSF55608 119 220 7.94E-20 T 28-03-2018 IPR027434 Homing endonuclease GO:0004519 CDW54_RS11040 46c90bd68cffabbb45846af73a641ed0 311 Gene3D G3DSA:3.10.28.10 122 202 1.6E-17 T 28-03-2018 IPR027434 Homing endonuclease GO:0004519 CDW54_RS11040 46c90bd68cffabbb45846af73a641ed0 311 Pfam PF02650 WhiA C-terminal HTH domain 219 303 4.3E-37 T 28-03-2018 IPR023054 Sporulation regulator WhiA, C-terminal CDW54_RS11040 46c90bd68cffabbb45846af73a641ed0 311 Gene3D G3DSA:3.10.28.10 14 98 3.8E-11 T 28-03-2018 IPR027434 Homing endonuclease GO:0004519 CDW54_RS11040 46c90bd68cffabbb45846af73a641ed0 311 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 19 102 2.9E-35 T 28-03-2018 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain CDW54_RS11040 46c90bd68cffabbb45846af73a641ed0 311 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 4 304 2.2E-122 T 28-03-2018 IPR033981 Sporulation regulator WhiA-like CDW54_RS10855 73bd4998210e3b970c9e4ebefda575d7 569 Gene3D G3DSA:3.30.930.10 11 457 6.6E-100 T 28-03-2018 CDW54_RS10855 73bd4998210e3b970c9e4ebefda575d7 569 Pfam PF04073 Aminoacyl-tRNA editing domain 257 374 2.3E-26 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CDW54_RS10855 73bd4998210e3b970c9e4ebefda575d7 569 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 566 40.591 T 28-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 CDW54_RS10855 73bd4998210e3b970c9e4ebefda575d7 569 SUPERFAMILY SSF55826 218 386 4.45E-36 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CDW54_RS10855 73bd4998210e3b970c9e4ebefda575d7 569 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 1.2E-17 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CDW54_RS10855 73bd4998210e3b970c9e4ebefda575d7 569 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 1.2E-17 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CDW54_RS10855 73bd4998210e3b970c9e4ebefda575d7 569 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 1.2E-17 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CDW54_RS10855 73bd4998210e3b970c9e4ebefda575d7 569 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 1.2E-17 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CDW54_RS10855 73bd4998210e3b970c9e4ebefda575d7 569 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 94 456 1.5E-70 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDW54_RS10855 73bd4998210e3b970c9e4ebefda575d7 569 SUPERFAMILY SSF55681 9 237 1.62E-98 T 28-03-2018 CDW54_RS10855 73bd4998210e3b970c9e4ebefda575d7 569 SUPERFAMILY SSF55681 404 475 1.62E-98 T 28-03-2018 CDW54_RS10855 73bd4998210e3b970c9e4ebefda575d7 569 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 560 2.1E-230 T 28-03-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 CDW54_RS10855 73bd4998210e3b970c9e4ebefda575d7 569 Gene3D G3DSA:3.40.50.800 458 569 3.0E-27 T 28-03-2018 IPR004154 Anticodon-binding CDW54_RS10855 73bd4998210e3b970c9e4ebefda575d7 569 Pfam PF03129 Anticodon binding domain 478 561 1.4E-14 T 28-03-2018 IPR004154 Anticodon-binding CDW54_RS10855 73bd4998210e3b970c9e4ebefda575d7 569 SUPERFAMILY SSF52954 461 566 3.27E-24 T 28-03-2018 IPR004154 Anticodon-binding CDW54_RS05825 e4d41018c6bc7dceffafd05a2913a86f 433 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 345 417 2.2E-27 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CDW54_RS05825 e4d41018c6bc7dceffafd05a2913a86f 433 SUPERFAMILY SSF54680 332 431 1.83E-28 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CDW54_RS05825 e4d41018c6bc7dceffafd05a2913a86f 433 Gene3D G3DSA:3.90.1170.30 338 423 6.0E-29 T 28-03-2018 CDW54_RS05825 e4d41018c6bc7dceffafd05a2913a86f 433 SUPERFAMILY SSF52418 69 329 3.92E-93 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CDW54_RS05825 e4d41018c6bc7dceffafd05a2913a86f 433 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 3 417 3.8E-179 T 28-03-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 CDW54_RS05825 e4d41018c6bc7dceffafd05a2913a86f 433 Gene3D G3DSA:1.20.970.10 1 66 7.3E-25 T 28-03-2018 CDW54_RS05825 e4d41018c6bc7dceffafd05a2913a86f 433 Gene3D G3DSA:3.40.1030.10 68 337 7.1E-94 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CDW54_RS05825 e4d41018c6bc7dceffafd05a2913a86f 433 PIRSF PIRSF000478 1 432 2.0E-168 T 28-03-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CDW54_RS05825 e4d41018c6bc7dceffafd05a2913a86f 433 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 110 125 - T 28-03-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CDW54_RS05825 e4d41018c6bc7dceffafd05a2913a86f 433 Pfam PF00591 Glycosyl transferase family, a/b domain 78 306 1.6E-44 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CDW54_RS05825 e4d41018c6bc7dceffafd05a2913a86f 433 SUPERFAMILY SSF47648 1 69 1.57E-22 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CDW54_RS05825 e4d41018c6bc7dceffafd05a2913a86f 433 Pfam PF02885 Glycosyl transferase family, helical bundle domain 4 66 7.8E-21 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CDW54_RS05825 e4d41018c6bc7dceffafd05a2913a86f 433 SMART SM00941 345 418 1.4E-30 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CDW54_RS12255 f2fd196903e08f31c9d44a32b541a393 314 Pfam PF12833 Helix-turn-helix domain 235 312 1.7E-12 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CDW54_RS12255 f2fd196903e08f31c9d44a32b541a393 314 Gene3D G3DSA:1.10.10.60 261 314 2.8E-9 T 28-03-2018 CDW54_RS12255 f2fd196903e08f31c9d44a32b541a393 314 SUPERFAMILY SSF51182 46 113 8.89E-8 T 28-03-2018 IPR011051 RmlC-like cupin domain CDW54_RS12255 f2fd196903e08f31c9d44a32b541a393 314 SUPERFAMILY SSF46689 265 313 1.88E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDW54_RS12255 f2fd196903e08f31c9d44a32b541a393 314 Gene3D G3DSA:1.10.10.60 211 260 1.2E-5 T 28-03-2018 CDW54_RS12255 f2fd196903e08f31c9d44a32b541a393 314 Pfam PF02311 AraC-like ligand binding domain 47 108 7.0E-6 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CDW54_RS12255 f2fd196903e08f31c9d44a32b541a393 314 SMART SM00342 228 311 2.9E-11 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CDW54_RS12255 f2fd196903e08f31c9d44a32b541a393 314 Gene3D G3DSA:2.60.120.280 27 202 3.6E-15 T 28-03-2018 CDW54_RS04035 a81e0b7fc6aa7b01c2095ed5e49b4e42 627 Pfam PF01757 Acyltransferase family 15 342 5.1E-23 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CDW54_RS04035 a81e0b7fc6aa7b01c2095ed5e49b4e42 627 Gene3D G3DSA:3.40.50.1110 408 613 6.1E-21 T 28-03-2018 CDW54_RS04035 a81e0b7fc6aa7b01c2095ed5e49b4e42 627 SUPERFAMILY SSF52266 456 611 3.66E-13 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CDW54_RS01710 1af35cc1b8cd8d12b6026ec9456ece2b 66 Gene3D G3DSA:2.40.50.140 1 66 3.7E-29 T 28-03-2018 CDW54_RS01710 1af35cc1b8cd8d12b6026ec9456ece2b 66 SUPERFAMILY SSF50249 1 65 4.52E-25 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDW54_RS01710 1af35cc1b8cd8d12b6026ec9456ece2b 66 PRINTS PR00050 Cold shock protein signature 39 57 2.2E-19 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CDW54_RS01710 1af35cc1b8cd8d12b6026ec9456ece2b 66 PRINTS PR00050 Cold shock protein signature 4 19 2.2E-19 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CDW54_RS01710 1af35cc1b8cd8d12b6026ec9456ece2b 66 PRINTS PR00050 Cold shock protein signature 24 33 2.2E-19 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CDW54_RS01710 1af35cc1b8cd8d12b6026ec9456ece2b 66 PIRSF PIRSF002599 1 66 4.2E-24 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 CDW54_RS01710 1af35cc1b8cd8d12b6026ec9456ece2b 66 SMART SM00357 3 66 1.3E-29 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CDW54_RS01710 1af35cc1b8cd8d12b6026ec9456ece2b 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 28-03-2018 IPR019844 Cold-shock conserved site CDW54_RS01710 1af35cc1b8cd8d12b6026ec9456ece2b 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 1.3E-30 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CDW54_RS09720 fd7f2a44813a150db4c483c7eb24691d 214 Pfam PF09186 Domain of unknown function (DUF1949) 142 195 6.4E-12 T 28-03-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal CDW54_RS09720 fd7f2a44813a150db4c483c7eb24691d 214 Gene3D G3DSA:3.30.70.240 135 198 4.6E-14 T 28-03-2018 CDW54_RS09720 fd7f2a44813a150db4c483c7eb24691d 214 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 1 200 4.8E-70 T 28-03-2018 IPR015796 Impact family, bacterial/archaeal CDW54_RS09720 fd7f2a44813a150db4c483c7eb24691d 214 SUPERFAMILY SSF54980 135 200 2.16E-10 T 28-03-2018 IPR035647 EF-G domain III/V-like CDW54_RS09720 fd7f2a44813a150db4c483c7eb24691d 214 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 79 108 - T 28-03-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site CDW54_RS09720 fd7f2a44813a150db4c483c7eb24691d 214 Gene3D G3DSA:3.30.230.30 4 133 1.8E-49 T 28-03-2018 IPR001498 Impact, N-terminal CDW54_RS09720 fd7f2a44813a150db4c483c7eb24691d 214 Pfam PF01205 Uncharacterized protein family UPF0029 19 124 9.0E-34 T 28-03-2018 IPR001498 Impact, N-terminal CDW54_RS09720 fd7f2a44813a150db4c483c7eb24691d 214 SUPERFAMILY SSF54211 2 131 9.1E-46 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CDW54_RS02070 006fc3b905c81d6fd83743c993a9616f 320 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 19 319 1.2E-93 T 28-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CDW54_RS02070 006fc3b905c81d6fd83743c993a9616f 320 ProSitePatterns PS01347 MraY family signature 1. 48 60 - T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CDW54_RS02070 006fc3b905c81d6fd83743c993a9616f 320 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 48 60 6.9E-6 T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CDW54_RS02070 006fc3b905c81d6fd83743c993a9616f 320 ProSitePatterns PS01348 MraY family signature 2. 166 177 - T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CDW54_RS02070 006fc3b905c81d6fd83743c993a9616f 320 Pfam PF00953 Glycosyl transferase family 4 82 246 1.3E-38 T 28-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CDW54_RS02070 006fc3b905c81d6fd83743c993a9616f 320 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 5 320 22.958 T 28-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CDW54_RS05005 94eefae71d94c00d372a8f587e18afe8 268 PIRSF PIRSF000193 1 267 9.7E-72 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CDW54_RS05005 94eefae71d94c00d372a8f587e18afe8 268 SUPERFAMILY SSF51735 1 156 4.97E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS05005 94eefae71d94c00d372a8f587e18afe8 268 Gene3D G3DSA:1.10.3730.10 159 268 3.0E-29 T 28-03-2018 CDW54_RS05005 94eefae71d94c00d372a8f587e18afe8 268 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 1 264 24.751 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CDW54_RS05005 94eefae71d94c00d372a8f587e18afe8 268 SUPERFAMILY SSF48179 160 264 4.93E-27 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CDW54_RS05005 94eefae71d94c00d372a8f587e18afe8 268 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 160 264 1.5E-28 T 28-03-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 CDW54_RS05005 94eefae71d94c00d372a8f587e18afe8 268 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 3 263 5.3E-79 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CDW54_RS05005 94eefae71d94c00d372a8f587e18afe8 268 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 96 7.5E-24 T 28-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CDW54_RS05005 94eefae71d94c00d372a8f587e18afe8 268 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 220 242 - T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CDW54_RS05005 94eefae71d94c00d372a8f587e18afe8 268 Gene3D G3DSA:3.40.50.720 1 158 1.6E-28 T 28-03-2018 CDW54_RS12015 705e6f28e1bef266cd8793572b5e6d24 215 Gene3D G3DSA:3.10.450.40 71 125 3.4E-10 T 28-03-2018 CDW54_RS12015 705e6f28e1bef266cd8793572b5e6d24 215 Gene3D G3DSA:3.10.450.40 154 213 6.0E-16 T 28-03-2018 CDW54_RS12015 705e6f28e1bef266cd8793572b5e6d24 215 Pfam PF03413 Peptidase propeptide and YPEB domain 154 212 5.7E-9 T 28-03-2018 IPR025711 PepSY domain CDW54_RS12015 705e6f28e1bef266cd8793572b5e6d24 215 Pfam PF03413 Peptidase propeptide and YPEB domain 70 122 7.6E-6 T 28-03-2018 IPR025711 PepSY domain CDW54_RS11035 d2549e852190f74cbc47f8c18be3661b 332 SUPERFAMILY SSF142338 10 324 1.83E-102 T 28-03-2018 CDW54_RS11035 d2549e852190f74cbc47f8c18be3661b 332 Gene3D G3DSA:3.40.50.10680 90 331 1.6E-58 T 28-03-2018 CDW54_RS11035 d2549e852190f74cbc47f8c18be3661b 332 Pfam PF01933 Uncharacterised protein family UPF0052 13 304 8.4E-99 T 28-03-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 CDW54_RS11035 d2549e852190f74cbc47f8c18be3661b 332 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 13 326 3.2E-116 T 28-03-2018 IPR010119 Gluconeogenesis factor CDW54_RS11035 d2549e852190f74cbc47f8c18be3661b 332 Hamap MF_00973 Gluconeogenesis factor. 9 329 34.165 T 28-03-2018 IPR010119 Gluconeogenesis factor CDW54_RS03540 cab0aec1bd23197c8e330716c3a855a0 232 SUPERFAMILY SSF53639 1 222 5.49E-74 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CDW54_RS03540 cab0aec1bd23197c8e330716c3a855a0 232 Gene3D G3DSA:3.40.225.10 1 230 1.2E-63 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CDW54_RS03540 cab0aec1bd23197c8e330716c3a855a0 232 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 8 196 6.8E-49 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CDW54_RS03540 cab0aec1bd23197c8e330716c3a855a0 232 SMART SM01007 7 197 5.8E-71 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CDW54_RS00435 cb4bae5914fc59e756613998e86b715a 377 SUPERFAMILY SSF56059 109 306 1.57E-65 T 28-03-2018 CDW54_RS00435 cb4bae5914fc59e756613998e86b715a 377 Gene3D G3DSA:3.40.50.20 12 96 5.6E-26 T 28-03-2018 CDW54_RS00435 cb4bae5914fc59e756613998e86b715a 377 SUPERFAMILY SSF52440 7 91 6.76E-26 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CDW54_RS00435 cb4bae5914fc59e756613998e86b715a 377 Gene3D G3DSA:3.30.470.20 188 373 2.1E-41 T 28-03-2018 CDW54_RS00435 cb4bae5914fc59e756613998e86b715a 377 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 13 363 44.273 T 28-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 CDW54_RS00435 cb4bae5914fc59e756613998e86b715a 377 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 13 366 1.0E-121 T 28-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 CDW54_RS00435 cb4bae5914fc59e756613998e86b715a 377 Pfam PF02222 ATP-grasp domain 118 287 2.4E-56 T 28-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type CDW54_RS00435 cb4bae5914fc59e756613998e86b715a 377 Gene3D G3DSA:3.30.1490.20 125 187 1.8E-19 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CDW54_RS00435 cb4bae5914fc59e756613998e86b715a 377 SUPERFAMILY SSF51246 312 376 2.12E-16 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CDW54_RS05860 fb1d47543269fa8c79e7dcb2d9e4c292 388 TIGRFAM TIGR01696 deoB: phosphopentomutase 4 382 1.8E-186 T 28-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CDW54_RS05860 fb1d47543269fa8c79e7dcb2d9e4c292 388 SUPERFAMILY SSF53649 215 387 7.42E-76 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CDW54_RS05860 fb1d47543269fa8c79e7dcb2d9e4c292 388 SUPERFAMILY SSF53649 1 98 7.42E-76 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CDW54_RS05860 fb1d47543269fa8c79e7dcb2d9e4c292 388 Gene3D G3DSA:3.40.720.10 201 388 4.4E-13 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CDW54_RS05860 fb1d47543269fa8c79e7dcb2d9e4c292 388 Pfam PF01676 Metalloenzyme superfamily 3 374 3.2E-43 T 28-03-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 CDW54_RS05860 fb1d47543269fa8c79e7dcb2d9e4c292 388 Gene3D G3DSA:3.30.70.1250 97 200 1.5E-54 T 28-03-2018 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CDW54_RS05860 fb1d47543269fa8c79e7dcb2d9e4c292 388 PIRSF PIRSF001491 1 388 4.2E-164 T 28-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CDW54_RS05860 fb1d47543269fa8c79e7dcb2d9e4c292 388 SUPERFAMILY SSF143856 98 214 1.44E-50 T 28-03-2018 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CDW54_RS05860 fb1d47543269fa8c79e7dcb2d9e4c292 388 Hamap MF_00740 Phosphopentomutase [deoB]. 2 384 54.987 T 28-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CDW54_RS11105 225cf2db802cfe8bf5e215385f51f6b6 601 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 601 37.693 T 28-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CDW54_RS11105 225cf2db802cfe8bf5e215385f51f6b6 601 Pfam PF01380 SIS domain 286 413 3.2E-31 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CDW54_RS11105 225cf2db802cfe8bf5e215385f51f6b6 601 Pfam PF01380 SIS domain 458 582 2.4E-17 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CDW54_RS11105 225cf2db802cfe8bf5e215385f51f6b6 601 Pfam PF13522 Glutamine amidotransferase domain 59 190 4.4E-21 T 28-03-2018 CDW54_RS11105 225cf2db802cfe8bf5e215385f51f6b6 601 SUPERFAMILY SSF56235 2 231 1.08E-66 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CDW54_RS11105 225cf2db802cfe8bf5e215385f51f6b6 601 Gene3D G3DSA:3.60.20.10 2 237 7.5E-60 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CDW54_RS11105 225cf2db802cfe8bf5e215385f51f6b6 601 Gene3D G3DSA:3.40.50.10490 238 452 6.0E-51 T 28-03-2018 CDW54_RS11105 225cf2db802cfe8bf5e215385f51f6b6 601 Gene3D G3DSA:3.40.50.10490 453 599 1.7E-42 T 28-03-2018 CDW54_RS11105 225cf2db802cfe8bf5e215385f51f6b6 601 SUPERFAMILY SSF53697 243 601 1.78E-91 T 28-03-2018 CDW54_RS11105 225cf2db802cfe8bf5e215385f51f6b6 601 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 601 5.7E-215 T 28-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CDW54_RS09680 356144922f41f8c1f6c4344206be5771 58 Pfam PF11772 DNA-directed RNA polymerase subunit beta 14 57 1.3E-20 T 28-03-2018 IPR024596 DNA-directed RNA polymerase subunit beta/EpuA CDW54_RS09680 356144922f41f8c1f6c4344206be5771 58 ProDom PD053619 EPUA PRECURSOR SIGNAL PEPTIDE YFDG EXTRACELLULAR OB2955 BH3736 GBS0884 SMU.1524C 1 57 1.0E-6 T 28-03-2018 IPR024596 DNA-directed RNA polymerase subunit beta/EpuA CDW54_RS02195 7a8440988d91ee2a9e72cf2c40d43d39 97 ProSitePatterns PS00831 Ribosomal protein L27 signature. 43 57 - T 28-03-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS02195 7a8440988d91ee2a9e72cf2c40d43d39 97 TIGRFAM TIGR00062 L27: ribosomal protein bL27 10 90 8.4E-40 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS02195 7a8440988d91ee2a9e72cf2c40d43d39 97 Pfam PF01016 Ribosomal L27 protein 11 90 7.0E-35 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS02195 7a8440988d91ee2a9e72cf2c40d43d39 97 PRINTS PR00063 Ribosomal protein L27 signature 38 62 1.3E-38 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS02195 7a8440988d91ee2a9e72cf2c40d43d39 97 PRINTS PR00063 Ribosomal protein L27 signature 63 87 1.3E-38 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS02195 7a8440988d91ee2a9e72cf2c40d43d39 97 PRINTS PR00063 Ribosomal protein L27 signature 13 37 1.3E-38 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS02195 7a8440988d91ee2a9e72cf2c40d43d39 97 Gene3D G3DSA:2.40.50.100 29 93 3.0E-29 T 28-03-2018 CDW54_RS02195 7a8440988d91ee2a9e72cf2c40d43d39 97 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 37 78 3.0E-17 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS02195 7a8440988d91ee2a9e72cf2c40d43d39 97 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 10 93 27.509 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS02195 7a8440988d91ee2a9e72cf2c40d43d39 97 SUPERFAMILY SSF110324 11 92 9.07E-33 T 28-03-2018 CDW54_RS02830 ac25a4c9857cc5e900cd953f09c73c14 274 Gene3D G3DSA:3.60.10.10 1 274 8.6E-32 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CDW54_RS02830 ac25a4c9857cc5e900cd953f09c73c14 274 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 5 266 2.9E-12 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CDW54_RS02830 ac25a4c9857cc5e900cd953f09c73c14 274 SUPERFAMILY SSF56219 1 273 5.63E-30 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CDW54_RS12360 c21d487ff7773331bdd6cafc7a876621 310 Pfam PF01180 Dihydroorotate dehydrogenase 6 289 5.1E-99 T 28-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CDW54_RS12360 c21d487ff7773331bdd6cafc7a876621 310 PIRSF PIRSF000164 1 302 8.5E-82 T 28-03-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 CDW54_RS12360 c21d487ff7773331bdd6cafc7a876621 310 SUPERFAMILY SSF51395 5 301 9.99E-84 T 28-03-2018 CDW54_RS12360 c21d487ff7773331bdd6cafc7a876621 310 Gene3D G3DSA:3.20.20.70 1 310 7.1E-63 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDW54_RS12360 c21d487ff7773331bdd6cafc7a876621 310 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 242 262 - T 28-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CDW54_RS12360 c21d487ff7773331bdd6cafc7a876621 310 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 42 61 - T 28-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CDW54_RS12360 c21d487ff7773331bdd6cafc7a876621 310 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 6 304 40.548 T 28-03-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 CDW54_RS12360 c21d487ff7773331bdd6cafc7a876621 310 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 6 301 3.6E-115 T 28-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CDW54_RS09085 501e19a6c68c38b3a89fe5fe539bb48d 250 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 248 8.5E-90 T 28-03-2018 CDW54_RS09085 501e19a6c68c38b3a89fe5fe539bb48d 250 SUPERFAMILY SSF56219 1 250 6.54E-84 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CDW54_RS09085 501e19a6c68c38b3a89fe5fe539bb48d 250 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 5 242 9.2E-24 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CDW54_RS09085 501e19a6c68c38b3a89fe5fe539bb48d 250 ProSitePatterns PS00728 AP endonucleases family 1 signature 3. 210 221 - T 28-03-2018 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 Reactome: R-HSA-110357|Reactome: R-HSA-110362|Reactome: R-HSA-110373|Reactome: R-HSA-5651801|Reactome: R-HSA-73930|Reactome: R-HSA-73933 CDW54_RS09085 501e19a6c68c38b3a89fe5fe539bb48d 250 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 28 37 - T 28-03-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 CDW54_RS09085 501e19a6c68c38b3a89fe5fe539bb48d 250 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 250 2.5E-93 T 28-03-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 CDW54_RS09085 501e19a6c68c38b3a89fe5fe539bb48d 250 Gene3D G3DSA:3.60.10.10 1 250 1.8E-58 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CDW54_RS10080 686f0874fff3bb4074acb07e16eb5a75 388 PIRSF PIRSF500134 1 345 1.3E-111 T 28-03-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 CDW54_RS10080 686f0874fff3bb4074acb07e16eb5a75 388 PIRSF PIRSF500134 338 388 0.24 T 28-03-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 CDW54_RS10080 686f0874fff3bb4074acb07e16eb5a75 388 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2 168 3.6E-28 T 28-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CDW54_RS10080 686f0874fff3bb4074acb07e16eb5a75 388 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 2 377 1.2E-99 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CDW54_RS10080 686f0874fff3bb4074acb07e16eb5a75 388 SUPERFAMILY SSF52413 283 388 5.62E-28 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CDW54_RS10080 686f0874fff3bb4074acb07e16eb5a75 388 SUPERFAMILY SSF48179 191 287 2.89E-30 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CDW54_RS10080 686f0874fff3bb4074acb07e16eb5a75 388 Gene3D G3DSA:3.40.50.720 288 388 4.1E-18 T 28-03-2018 CDW54_RS10080 686f0874fff3bb4074acb07e16eb5a75 388 SMART SM00984 300 387 6.1E-16 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CDW54_RS10080 686f0874fff3bb4074acb07e16eb5a75 388 Gene3D G3DSA:3.40.50.720 1 193 3.8E-42 T 28-03-2018 CDW54_RS10080 686f0874fff3bb4074acb07e16eb5a75 388 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 192 281 1.7E-26 T 28-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CDW54_RS10080 686f0874fff3bb4074acb07e16eb5a75 388 Gene3D G3DSA:1.20.5.100 194 211 5.6E-14 T 28-03-2018 CDW54_RS10080 686f0874fff3bb4074acb07e16eb5a75 388 Gene3D G3DSA:1.10.1040.10 212 287 2.7E-27 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CDW54_RS10080 686f0874fff3bb4074acb07e16eb5a75 388 PIRSF PIRSF000124 1 388 2.8E-131 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CDW54_RS10080 686f0874fff3bb4074acb07e16eb5a75 388 SUPERFAMILY SSF51735 2 194 5.16E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS10080 686f0874fff3bb4074acb07e16eb5a75 388 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 301 366 1.9E-8 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CDW54_RS05225 b0bb9b1ad6ab7dbd3fa335a5132ff3b8 549 SUPERFAMILY SSF52540 321 538 7.93E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS05225 b0bb9b1ad6ab7dbd3fa335a5132ff3b8 549 SMART SM00534 351 537 6.1E-10 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CDW54_RS05225 b0bb9b1ad6ab7dbd3fa335a5132ff3b8 549 Pfam PF00488 MutS domain V 355 538 2.4E-26 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CDW54_RS05225 b0bb9b1ad6ab7dbd3fa335a5132ff3b8 549 Gene3D G3DSA:3.40.50.300 320 542 9.7E-14 T 28-03-2018 CDW54_RS05225 b0bb9b1ad6ab7dbd3fa335a5132ff3b8 549 Gene3D G3DSA:1.10.1420.10 66 317 2.0E-6 T 28-03-2018 CDW54_RS06565 08a0b6d14690c413bc4d9cd1c321f945 358 SUPERFAMILY SSF52440 2 130 1.44E-35 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CDW54_RS06565 08a0b6d14690c413bc4d9cd1c321f945 358 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 2 341 3.1E-104 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDW54_RS06565 08a0b6d14690c413bc4d9cd1c321f945 358 Pfam PF01820 D-ala D-ala ligase N-terminus 2 120 1.1E-28 T 28-03-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDW54_RS06565 08a0b6d14690c413bc4d9cd1c321f945 358 PIRSF PIRSF039102 1 352 1.0E-106 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDW54_RS06565 08a0b6d14690c413bc4d9cd1c321f945 358 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 286 314 - T 28-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDW54_RS06565 08a0b6d14690c413bc4d9cd1c321f945 358 Pfam PF07478 D-ala D-ala ligase C-terminus 138 341 4.7E-80 T 28-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDW54_RS06565 08a0b6d14690c413bc4d9cd1c321f945 358 Gene3D G3DSA:3.30.470.20 207 353 2.2E-38 T 28-03-2018 CDW54_RS06565 08a0b6d14690c413bc4d9cd1c321f945 358 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 1 344 40.309 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDW54_RS06565 08a0b6d14690c413bc4d9cd1c321f945 358 SUPERFAMILY SSF56059 131 349 4.07E-56 T 28-03-2018 CDW54_RS06565 08a0b6d14690c413bc4d9cd1c321f945 358 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 98 109 - T 28-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDW54_RS06565 08a0b6d14690c413bc4d9cd1c321f945 358 Gene3D G3DSA:3.30.1490.20 133 206 3.3E-18 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CDW54_RS06565 08a0b6d14690c413bc4d9cd1c321f945 358 Gene3D G3DSA:3.40.50.20 1 132 4.0E-40 T 28-03-2018 CDW54_RS02560 3b781dfc66bf0c36de36be47042e21a2 217 SUPERFAMILY SSF56784 1 216 2.07E-46 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS02560 3b781dfc66bf0c36de36be47042e21a2 217 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 1.5E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDW54_RS02560 3b781dfc66bf0c36de36be47042e21a2 217 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 132 148 1.5E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDW54_RS02560 3b781dfc66bf0c36de36be47042e21a2 217 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 150 170 1.5E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDW54_RS02560 3b781dfc66bf0c36de36be47042e21a2 217 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 93 181 1.2E-5 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDW54_RS02560 3b781dfc66bf0c36de36be47042e21a2 217 Gene3D G3DSA:3.40.50.1000 78 217 1.2E-24 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS02560 3b781dfc66bf0c36de36be47042e21a2 217 Gene3D G3DSA:1.10.150.240 27 77 1.6E-8 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CDW54_RS02560 3b781dfc66bf0c36de36be47042e21a2 217 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 58 188 1.7E-14 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDW54_RS02560 3b781dfc66bf0c36de36be47042e21a2 217 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 188 8.0E-32 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS02560 3b781dfc66bf0c36de36be47042e21a2 217 Gene3D G3DSA:3.40.50.1000 1 26 0.11 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS12680 5ddc7fa3e045732aebad4f2c54e4cbfc 337 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 28 334 1.5E-138 T 28-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 CDW54_RS12680 5ddc7fa3e045732aebad4f2c54e4cbfc 337 SUPERFAMILY SSF56752 2 333 6.93E-104 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CDW54_RS12680 5ddc7fa3e045732aebad4f2c54e4cbfc 337 Pfam PF01063 Amino-transferase class IV 53 290 3.0E-36 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CDW54_RS12680 5ddc7fa3e045732aebad4f2c54e4cbfc 337 Gene3D G3DSA:3.30.470.10 1 165 3.7E-56 T 28-03-2018 CDW54_RS12680 5ddc7fa3e045732aebad4f2c54e4cbfc 337 Gene3D G3DSA:3.20.10.10 166 319 2.6E-39 T 28-03-2018 CDW54_RS12680 5ddc7fa3e045732aebad4f2c54e4cbfc 337 ProSitePatterns PS00770 Aminotransferases class-IV signature. 217 246 - T 28-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 CDW54_RS12680 5ddc7fa3e045732aebad4f2c54e4cbfc 337 PIRSF PIRSF006468 1 337 4.7E-120 T 28-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 CDW54_RS02115 e7b042aae61ec1345ebfd0dac0d29286 149 Gene3D G3DSA:1.10.10.10 3 66 1.4E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS02115 e7b042aae61ec1345ebfd0dac0d29286 149 SUPERFAMILY SSF55252 80 148 3.53E-16 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CDW54_RS02115 e7b042aae61ec1345ebfd0dac0d29286 149 Pfam PF02863 Arginine repressor, C-terminal domain 80 144 1.5E-16 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CDW54_RS02115 e7b042aae61ec1345ebfd0dac0d29286 149 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 87 149 5.0E-8 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CDW54_RS02115 e7b042aae61ec1345ebfd0dac0d29286 149 Hamap MF_00173 Arginine repressor [argR]. 1 149 53.935 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CDW54_RS02115 e7b042aae61ec1345ebfd0dac0d29286 149 Gene3D G3DSA:3.30.1360.40 74 146 5.1E-19 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CDW54_RS02115 e7b042aae61ec1345ebfd0dac0d29286 149 PRINTS PR01467 Bacterial arginine repressor signature 37 52 4.8E-16 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CDW54_RS02115 e7b042aae61ec1345ebfd0dac0d29286 149 PRINTS PR01467 Bacterial arginine repressor signature 118 133 4.8E-16 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CDW54_RS02115 e7b042aae61ec1345ebfd0dac0d29286 149 PRINTS PR01467 Bacterial arginine repressor signature 21 34 4.8E-16 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CDW54_RS02115 e7b042aae61ec1345ebfd0dac0d29286 149 PRINTS PR01467 Bacterial arginine repressor signature 88 101 4.8E-16 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CDW54_RS02115 e7b042aae61ec1345ebfd0dac0d29286 149 SUPERFAMILY SSF46785 3 76 2.68E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS02115 e7b042aae61ec1345ebfd0dac0d29286 149 Pfam PF01316 Arginine repressor, DNA binding domain 1 69 6.4E-25 T 28-03-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 CDW54_RS09625 bb923a4733abfa049730db6d369c1847 154 SUPERFAMILY SSF74982 4 132 8.37E-53 T 28-03-2018 IPR023620 Small protein B CDW54_RS09625 bb923a4733abfa049730db6d369c1847 154 ProSitePatterns PS01317 SsrA-binding protein. 27 39 - T 28-03-2018 IPR020081 SsrA-binding protein, conserved site CDW54_RS09625 bb923a4733abfa049730db6d369c1847 154 Hamap MF_00023 SsrA-binding protein [smpB]. 1 154 73.24 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 CDW54_RS09625 bb923a4733abfa049730db6d369c1847 154 Gene3D G3DSA:2.40.280.10 9 127 2.0E-51 T 28-03-2018 IPR023620 Small protein B CDW54_RS09625 bb923a4733abfa049730db6d369c1847 154 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 9 132 6.0E-67 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 CDW54_RS09625 bb923a4733abfa049730db6d369c1847 154 TIGRFAM TIGR00086 smpB: SsrA-binding protein 9 150 2.2E-59 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 CDW54_RS09625 bb923a4733abfa049730db6d369c1847 154 Pfam PF01668 SmpB protein 9 151 2.5E-62 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 CDW54_RS10390 5ec4b1c2a552d512d3fbd16d8dfaf011 184 Pfam PF03358 NADPH-dependent FMN reductase 4 149 1.6E-35 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CDW54_RS10390 5ec4b1c2a552d512d3fbd16d8dfaf011 184 Gene3D G3DSA:3.40.50.360 1 184 4.6E-35 T 28-03-2018 IPR029039 Flavoprotein-like domain CDW54_RS10390 5ec4b1c2a552d512d3fbd16d8dfaf011 184 SUPERFAMILY SSF52218 3 162 1.55E-44 T 28-03-2018 IPR029039 Flavoprotein-like domain CDW54_RS05805 a51d24885a6f873072f133c394753865 521 Gene3D G3DSA:3.40.50.620 218 396 5.3E-36 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDW54_RS05805 a51d24885a6f873072f133c394753865 521 PRINTS PR00097 Anthranilate synthase component II signature 84 95 6.4E-5 T 28-03-2018 CDW54_RS05805 a51d24885a6f873072f133c394753865 521 PRINTS PR00097 Anthranilate synthase component II signature 57 66 6.4E-5 T 28-03-2018 CDW54_RS05805 a51d24885a6f873072f133c394753865 521 PRINTS PR00097 Anthranilate synthase component II signature 173 186 6.4E-5 T 28-03-2018 CDW54_RS05805 a51d24885a6f873072f133c394753865 521 PRINTS PR00096 Glutamine amidotransferase superfamily signature 173 186 1.5E-6 T 28-03-2018 CDW54_RS05805 a51d24885a6f873072f133c394753865 521 PRINTS PR00096 Glutamine amidotransferase superfamily signature 57 66 1.5E-6 T 28-03-2018 CDW54_RS05805 a51d24885a6f873072f133c394753865 521 PRINTS PR00096 Glutamine amidotransferase superfamily signature 84 95 1.5E-6 T 28-03-2018 CDW54_RS05805 a51d24885a6f873072f133c394753865 521 Pfam PF00117 Glutamine amidotransferase class-I 15 195 3.5E-41 T 28-03-2018 IPR017926 Glutamine amidotransferase CDW54_RS05805 a51d24885a6f873072f133c394753865 521 Gene3D G3DSA:3.40.50.880 8 217 5.0E-48 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CDW54_RS05805 a51d24885a6f873072f133c394753865 521 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 13 201 5.8E-77 T 28-03-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CDW54_RS05805 a51d24885a6f873072f133c394753865 521 SUPERFAMILY SSF52317 10 233 9.01E-56 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CDW54_RS05805 a51d24885a6f873072f133c394753865 521 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 208 521 5.9E-152 T 28-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CDW54_RS05805 a51d24885a6f873072f133c394753865 521 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 84 100 7.8E-7 T 28-03-2018 CDW54_RS05805 a51d24885a6f873072f133c394753865 521 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 54 68 7.8E-7 T 28-03-2018 CDW54_RS05805 a51d24885a6f873072f133c394753865 521 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 13 27 7.8E-7 T 28-03-2018 CDW54_RS05805 a51d24885a6f873072f133c394753865 521 Pfam PF02540 NAD synthase 216 257 5.1E-8 T 28-03-2018 IPR022310 NAD/GMP synthase CDW54_RS05805 a51d24885a6f873072f133c394753865 521 Gene3D G3DSA:3.30.300.10 397 521 6.5E-52 T 28-03-2018 CDW54_RS05805 a51d24885a6f873072f133c394753865 521 Pfam PF00958 GMP synthase C terminal domain 429 520 2.4E-43 T 28-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CDW54_RS05805 a51d24885a6f873072f133c394753865 521 SUPERFAMILY SSF52402 190 443 1.99E-62 T 28-03-2018 CDW54_RS05805 a51d24885a6f873072f133c394753865 521 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 10 521 54.19 T 28-03-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 CDW54_RS00150 457ca24f1a1694d3df9b020f8cfe181b 166 Gene3D G3DSA:3.40.630.30 2 164 2.3E-15 T 28-03-2018 CDW54_RS00150 457ca24f1a1694d3df9b020f8cfe181b 166 SUPERFAMILY SSF55729 3 160 4.03E-18 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDW54_RS00150 457ca24f1a1694d3df9b020f8cfe181b 166 Pfam PF13302 Acetyltransferase (GNAT) domain 66 149 5.4E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CDW54_RS06505 5f55628efb3ed6f35871c28b77c81b37 456 TIGRFAM TIGR00797 matE: MATE efflux family protein 19 393 5.8E-72 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CDW54_RS06505 5f55628efb3ed6f35871c28b77c81b37 456 Pfam PF01554 MatE 241 394 7.5E-21 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CDW54_RS06505 5f55628efb3ed6f35871c28b77c81b37 456 Pfam PF01554 MatE 19 179 1.2E-37 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CDW54_RS06505 5f55628efb3ed6f35871c28b77c81b37 456 PIRSF PIRSF006603 1 409 2.8E-100 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CDW54_RS06505 5f55628efb3ed6f35871c28b77c81b37 456 PIRSF PIRSF006603 401 452 0.039 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CDW54_RS07215 c05e8a70dd24cd92291ba41ad2a0b720 548 SUPERFAMILY SSF100950 224 478 1.81E-19 T 28-03-2018 CDW54_RS07215 c05e8a70dd24cd92291ba41ad2a0b720 548 Pfam PF16957 Malonate decarboxylase, alpha subunit, transporter 7 547 3.7E-294 T 28-03-2018 IPR005777 Acetyl-S-ACP:malonate ACP transferase MetaCyc: PWY-5794|MetaCyc: PWY-6060 CDW54_RS07215 c05e8a70dd24cd92291ba41ad2a0b720 548 TIGRFAM TIGR01110 mdcA: malonate decarboxylase, alpha subunit 8 547 8.0E-277 T 28-03-2018 IPR005777 Acetyl-S-ACP:malonate ACP transferase MetaCyc: PWY-5794|MetaCyc: PWY-6060 CDW54_RS07215 c05e8a70dd24cd92291ba41ad2a0b720 548 SUPERFAMILY SSF100950 37 276 6.8E-33 T 28-03-2018 CDW54_RS07215 c05e8a70dd24cd92291ba41ad2a0b720 548 Gene3D G3DSA:3.40.1080.10 1 219 1.2E-31 T 28-03-2018 CDW54_RS07215 c05e8a70dd24cd92291ba41ad2a0b720 548 Gene3D G3DSA:3.40.1080.10 229 530 1.7E-40 T 28-03-2018 CDW54_RS11065 5dfb47d95663e9ef9ab150de313a1e86 1230 Gene3D G3DSA:4.10.780.10 635 671 2.6E-8 T 28-03-2018 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 CDW54_RS11065 5dfb47d95663e9ef9ab150de313a1e86 1230 SUPERFAMILY SSF52922 259 413 3.14E-44 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CDW54_RS11065 5dfb47d95663e9ef9ab150de313a1e86 1230 Gene3D G3DSA:3.40.920.10 417 626 7.5E-57 T 28-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CDW54_RS11065 5dfb47d95663e9ef9ab150de313a1e86 1230 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 960 1068 4.1E-10 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CDW54_RS11065 5dfb47d95663e9ef9ab150de313a1e86 1230 SMART SM00890 622 682 4.7E-12 T 28-03-2018 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 CDW54_RS11065 5dfb47d95663e9ef9ab150de313a1e86 1230 Pfam PF13484 4Fe-4S double cluster binding domain 691 758 2.6E-9 T 28-03-2018 CDW54_RS11065 5dfb47d95663e9ef9ab150de313a1e86 1230 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 426 607 4.3E-31 T 28-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CDW54_RS11065 5dfb47d95663e9ef9ab150de313a1e86 1230 Gene3D G3DSA:3.40.50.970 1 257 6.4E-49 T 28-03-2018 CDW54_RS11065 5dfb47d95663e9ef9ab150de313a1e86 1230 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 268 373 3.3E-19 T 28-03-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II CDW54_RS11065 5dfb47d95663e9ef9ab150de313a1e86 1230 Gene3D G3DSA:3.30.70.20 672 785 9.1E-27 T 28-03-2018 CDW54_RS11065 5dfb47d95663e9ef9ab150de313a1e86 1230 PIRSF PIRSF000159 1 1179 0.0 T 28-03-2018 IPR011895 Pyruvate-flavodoxin oxidoreductase GO:0005506|GO:0016903|GO:0022900|GO:0055114 CDW54_RS11065 5dfb47d95663e9ef9ab150de313a1e86 1230 Gene3D G3DSA:3.40.50.970 786 1174 1.3E-108 T 28-03-2018 CDW54_RS11065 5dfb47d95663e9ef9ab150de313a1e86 1230 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 21 247 3.9E-77 T 28-03-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 CDW54_RS11065 5dfb47d95663e9ef9ab150de313a1e86 1230 Pfam PF10371 Domain of unknown function 625 681 1.1E-11 T 28-03-2018 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 CDW54_RS11065 5dfb47d95663e9ef9ab150de313a1e86 1230 SUPERFAMILY SSF53323 417 662 2.48E-81 T 28-03-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CDW54_RS11065 5dfb47d95663e9ef9ab150de313a1e86 1230 TIGRFAM TIGR02176 pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase 4 1170 0.0 T 28-03-2018 IPR011895 Pyruvate-flavodoxin oxidoreductase GO:0005506|GO:0016903|GO:0022900|GO:0055114 CDW54_RS11065 5dfb47d95663e9ef9ab150de313a1e86 1230 Gene3D G3DSA:3.40.50.920 258 416 2.2E-41 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CDW54_RS11065 5dfb47d95663e9ef9ab150de313a1e86 1230 SUPERFAMILY SSF52518 3 257 1.15E-72 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CDW54_RS11065 5dfb47d95663e9ef9ab150de313a1e86 1230 SUPERFAMILY SSF54862 669 833 4.77E-23 T 28-03-2018 CDW54_RS11065 5dfb47d95663e9ef9ab150de313a1e86 1230 SUPERFAMILY SSF52518 792 1170 2.85E-123 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CDW54_RS11065 5dfb47d95663e9ef9ab150de313a1e86 1230 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 746 757 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CDW54_RS03680 734a39801a17f90e31093f03a552f59c 234 SUPERFAMILY SSF46894 129 229 1.16E-32 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDW54_RS03680 734a39801a17f90e31093f03a552f59c 234 Gene3D G3DSA:3.40.50.2300 1 124 1.2E-38 T 28-03-2018 CDW54_RS03680 734a39801a17f90e31093f03a552f59c 234 SMART SM00862 152 228 7.7E-28 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDW54_RS03680 734a39801a17f90e31093f03a552f59c 234 SUPERFAMILY SSF52172 1 124 2.28E-43 T 28-03-2018 IPR011006 CheY-like superfamily CDW54_RS03680 734a39801a17f90e31093f03a552f59c 234 Pfam PF00072 Response regulator receiver domain 4 113 1.4E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDW54_RS03680 734a39801a17f90e31093f03a552f59c 234 SMART SM00448 2 112 5.7E-47 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDW54_RS03680 734a39801a17f90e31093f03a552f59c 234 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 228 6.9E-27 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDW54_RS03680 734a39801a17f90e31093f03a552f59c 234 Gene3D G3DSA:1.10.10.10 125 234 1.6E-34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS12425 8d83f78514f32cdab3cce8b9a5250eda 77 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 2.5E-27 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CDW54_RS12425 8d83f78514f32cdab3cce8b9a5250eda 77 PRINTS PR00050 Cold shock protein signature 39 57 1.4E-16 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CDW54_RS12425 8d83f78514f32cdab3cce8b9a5250eda 77 PRINTS PR00050 Cold shock protein signature 24 33 1.4E-16 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CDW54_RS12425 8d83f78514f32cdab3cce8b9a5250eda 77 PRINTS PR00050 Cold shock protein signature 4 19 1.4E-16 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CDW54_RS12425 8d83f78514f32cdab3cce8b9a5250eda 77 SUPERFAMILY SSF50249 2 64 7.24E-22 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDW54_RS12425 8d83f78514f32cdab3cce8b9a5250eda 77 SMART SM00357 3 66 5.4E-24 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CDW54_RS12425 8d83f78514f32cdab3cce8b9a5250eda 77 PIRSF PIRSF002599 1 76 5.2E-21 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 CDW54_RS12425 8d83f78514f32cdab3cce8b9a5250eda 77 Gene3D G3DSA:2.40.50.140 1 66 1.5E-23 T 28-03-2018 CDW54_RS12425 8d83f78514f32cdab3cce8b9a5250eda 77 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 28-03-2018 IPR019844 Cold-shock conserved site CDW54_RS10470 53a7af8bf51a98e28d35e9058c368f9a 236 Gene3D G3DSA:3.30.1330.80 3 92 6.7E-33 T 28-03-2018 CDW54_RS10470 53a7af8bf51a98e28d35e9058c368f9a 236 PIRSF PIRSF001332 1 236 1.2E-90 T 28-03-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 CDW54_RS10470 53a7af8bf51a98e28d35e9058c368f9a 236 Pfam PF03306 Alpha-acetolactate decarboxylase 6 223 9.0E-80 T 28-03-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 CDW54_RS10470 53a7af8bf51a98e28d35e9058c368f9a 236 TIGRFAM TIGR01252 acetolac_decarb: alpha-acetolactate decarboxylase 6 236 3.4E-81 T 28-03-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 CDW54_RS10470 53a7af8bf51a98e28d35e9058c368f9a 236 SUPERFAMILY SSF117856 5 236 1.29E-78 T 28-03-2018 CDW54_RS10470 53a7af8bf51a98e28d35e9058c368f9a 236 Gene3D G3DSA:3.30.1330.80 93 200 3.4E-41 T 28-03-2018 CDW54_RS06645 d478fc58764a94677a84fdfbadf6c3ef 223 SUPERFAMILY SSF161098 22 208 2.35E-34 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS06645 d478fc58764a94677a84fdfbadf6c3ef 223 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 46 215 1.1E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS06645 d478fc58764a94677a84fdfbadf6c3ef 223 Gene3D G3DSA:1.10.3720.10 2 221 2.9E-29 T 28-03-2018 CDW54_RS08250 f9453bb42daf93dc1bcf0f751c337429 430 PRINTS PR01035 Tetracycline resistance protein signature 291 312 4.6E-9 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CDW54_RS08250 f9453bb42daf93dc1bcf0f751c337429 430 PRINTS PR01035 Tetracycline resistance protein signature 91 115 4.6E-9 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CDW54_RS08250 f9453bb42daf93dc1bcf0f751c337429 430 PRINTS PR01035 Tetracycline resistance protein signature 29 45 4.6E-9 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CDW54_RS08250 f9453bb42daf93dc1bcf0f751c337429 430 PRINTS PR01035 Tetracycline resistance protein signature 148 170 4.6E-9 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CDW54_RS08250 f9453bb42daf93dc1bcf0f751c337429 430 PRINTS PR01035 Tetracycline resistance protein signature 118 139 4.6E-9 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CDW54_RS08250 f9453bb42daf93dc1bcf0f751c337429 430 Pfam PF07690 Major Facilitator Superfamily 23 311 3.4E-38 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDW54_RS08250 f9453bb42daf93dc1bcf0f751c337429 430 Gene3D G3DSA:1.20.1250.20 6 202 1.6E-30 T 28-03-2018 CDW54_RS08250 f9453bb42daf93dc1bcf0f751c337429 430 Gene3D G3DSA:1.20.1250.20 212 416 2.7E-34 T 28-03-2018 CDW54_RS08250 f9453bb42daf93dc1bcf0f751c337429 430 SUPERFAMILY SSF103473 13 400 1.83E-71 T 28-03-2018 IPR020846 Major facilitator superfamily domain CDW54_RS04125 d7e52bc5309613b8a24857d4ad435f9a 319 SUPERFAMILY SSF53098 160 309 4.17E-21 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS04125 d7e52bc5309613b8a24857d4ad435f9a 319 Pfam PF00665 Integrase core domain 167 265 7.8E-10 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CDW54_RS04125 d7e52bc5309613b8a24857d4ad435f9a 319 Gene3D G3DSA:3.30.420.10 155 317 1.3E-21 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS04125 d7e52bc5309613b8a24857d4ad435f9a 319 Gene3D G3DSA:1.10.10.60 6 68 1.1E-4 T 28-03-2018 CDW54_RS02100 1e5345a2a7db436e47997e220f5696f6 318 Gene3D G3DSA:1.20.58.340 136 251 7.2E-13 T 28-03-2018 CDW54_RS02100 1e5345a2a7db436e47997e220f5696f6 318 Gene3D G3DSA:1.20.58.340 252 318 1.1E-12 T 28-03-2018 CDW54_RS02100 1e5345a2a7db436e47997e220f5696f6 318 Pfam PF01544 CorA-like Mg2+ transporter protein 20 314 4.3E-57 T 28-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 CDW54_RS02100 1e5345a2a7db436e47997e220f5696f6 318 SUPERFAMILY SSF143865 5 253 1.31E-29 T 28-03-2018 CDW54_RS02100 1e5345a2a7db436e47997e220f5696f6 318 SUPERFAMILY SSF144083 254 314 3.79E-15 T 28-03-2018 CDW54_RS02100 1e5345a2a7db436e47997e220f5696f6 318 Gene3D G3DSA:3.30.460.20 2 126 3.7E-14 T 28-03-2018 CDW54_RS09715 d0be97ac63ef1f3aad6e88c19b089cd6 235 SMART SM00866 91 230 2.2E-40 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CDW54_RS09715 d0be97ac63ef1f3aad6e88c19b089cd6 235 Gene3D G3DSA:1.10.10.10 1 69 1.8E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS09715 d0be97ac63ef1f3aad6e88c19b089cd6 235 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 70 2.1E-23 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDW54_RS09715 d0be97ac63ef1f3aad6e88c19b089cd6 235 SUPERFAMILY SSF64288 58 233 6.44E-48 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CDW54_RS09715 d0be97ac63ef1f3aad6e88c19b089cd6 235 Gene3D G3DSA:3.40.1410.10 70 234 1.0E-41 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CDW54_RS09715 d0be97ac63ef1f3aad6e88c19b089cd6 235 SUPERFAMILY SSF46785 3 74 3.03E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS09715 d0be97ac63ef1f3aad6e88c19b089cd6 235 SMART SM00345 11 70 4.1E-25 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDW54_RS09715 d0be97ac63ef1f3aad6e88c19b089cd6 235 Pfam PF07702 UTRA domain 91 230 8.0E-39 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CDW54_RS09715 d0be97ac63ef1f3aad6e88c19b089cd6 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 30 44 2.1E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDW54_RS09715 d0be97ac63ef1f3aad6e88c19b089cd6 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 60 2.1E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDW54_RS02345 9b371eb5b41a632e5b06044704fdefa6 214 Pfam PF02223 Thymidylate kinase 8 198 2.7E-53 T 28-03-2018 CDW54_RS02345 9b371eb5b41a632e5b06044704fdefa6 214 ProSitePatterns PS01331 Thymidylate kinase signature. 94 106 - T 28-03-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CDW54_RS02345 9b371eb5b41a632e5b06044704fdefa6 214 Hamap MF_00165 Thymidylate kinase [tmk]. 4 208 31.354 T 28-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CDW54_RS02345 9b371eb5b41a632e5b06044704fdefa6 214 SUPERFAMILY SSF52540 2 207 4.55E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS02345 9b371eb5b41a632e5b06044704fdefa6 214 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 2 198 2.1E-61 T 28-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CDW54_RS02345 9b371eb5b41a632e5b06044704fdefa6 214 Gene3D G3DSA:3.40.50.300 1 207 2.2E-55 T 28-03-2018 CDW54_RS06770 5a2b96f416776f428c086242c92f5e7d 119 PRINTS PR00062 Ribosomal protein L20 signature 75 101 3.5E-41 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS06770 5a2b96f416776f428c086242c92f5e7d 119 PRINTS PR00062 Ribosomal protein L20 signature 12 41 3.5E-41 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS06770 5a2b96f416776f428c086242c92f5e7d 119 PRINTS PR00062 Ribosomal protein L20 signature 42 71 3.5E-41 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS06770 5a2b96f416776f428c086242c92f5e7d 119 Pfam PF00453 Ribosomal protein L20 3 109 6.2E-49 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS06770 5a2b96f416776f428c086242c92f5e7d 119 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 4.5E-51 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS06770 5a2b96f416776f428c086242c92f5e7d 119 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS06770 5a2b96f416776f428c086242c92f5e7d 119 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 30.282 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS06770 5a2b96f416776f428c086242c92f5e7d 119 Gene3D G3DSA:1.10.1900.20 55 116 5.5E-29 T 28-03-2018 IPR035566 Ribosomal protein L20 C-terminal domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS06770 5a2b96f416776f428c086242c92f5e7d 119 SUPERFAMILY SSF74731 3 117 2.49E-49 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS06770 5a2b96f416776f428c086242c92f5e7d 119 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 24 70 5.0E-13 T 28-03-2018 CDW54_RS06125 17cfcf76e33b5ce9a775962818c96326 889 Gene3D G3DSA:2.60.120.260 627 848 1.6E-4 T 28-03-2018 IPR008979 Galactose-binding domain-like CDW54_RS06125 17cfcf76e33b5ce9a775962818c96326 889 Pfam PF09586 Bacterial membrane protein YfhO 19 846 3.9E-251 T 28-03-2018 IPR018580 Uncharacterised protein family YfhO CDW54_RS07395 14cb3f3fe6a250d38e2e9de0f2320ae2 238 Gene3D G3DSA:1.20.1080.10 2 238 8.4E-79 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CDW54_RS07395 14cb3f3fe6a250d38e2e9de0f2320ae2 238 TIGRFAM TIGR00861 MIP: MIP family channel proteins 10 234 7.4E-52 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CDW54_RS07395 14cb3f3fe6a250d38e2e9de0f2320ae2 238 PRINTS PR00783 Major intrinsic protein family signature 140 158 6.7E-46 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CDW54_RS07395 14cb3f3fe6a250d38e2e9de0f2320ae2 238 PRINTS PR00783 Major intrinsic protein family signature 170 192 6.7E-46 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CDW54_RS07395 14cb3f3fe6a250d38e2e9de0f2320ae2 238 PRINTS PR00783 Major intrinsic protein family signature 6 25 6.7E-46 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CDW54_RS07395 14cb3f3fe6a250d38e2e9de0f2320ae2 238 PRINTS PR00783 Major intrinsic protein family signature 85 104 6.7E-46 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CDW54_RS07395 14cb3f3fe6a250d38e2e9de0f2320ae2 238 PRINTS PR00783 Major intrinsic protein family signature 48 72 6.7E-46 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CDW54_RS07395 14cb3f3fe6a250d38e2e9de0f2320ae2 238 PRINTS PR00783 Major intrinsic protein family signature 217 237 6.7E-46 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CDW54_RS07395 14cb3f3fe6a250d38e2e9de0f2320ae2 238 Pfam PF00230 Major intrinsic protein 5 234 2.0E-41 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CDW54_RS07395 14cb3f3fe6a250d38e2e9de0f2320ae2 238 SUPERFAMILY SSF81338 5 237 4.06E-68 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CDW54_RS07395 14cb3f3fe6a250d38e2e9de0f2320ae2 238 ProSitePatterns PS00221 MIP family signature. 66 74 - T 28-03-2018 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CDW54_RS02615 99d571087808af4b03e22a030274a800 245 Gene3D G3DSA:3.10.129.10 1 135 6.0E-16 T 28-03-2018 CDW54_RS02615 99d571087808af4b03e22a030274a800 245 SUPERFAMILY SSF54637 151 242 2.38E-22 T 28-03-2018 IPR029069 HotDog domain CDW54_RS02615 99d571087808af4b03e22a030274a800 245 Gene3D G3DSA:3.10.129.10 143 243 4.7E-18 T 28-03-2018 CDW54_RS02615 99d571087808af4b03e22a030274a800 245 SUPERFAMILY SSF54637 3 145 8.02E-42 T 28-03-2018 IPR029069 HotDog domain CDW54_RS02615 99d571087808af4b03e22a030274a800 245 Pfam PF01643 Acyl-ACP thioesterase 3 244 9.9E-77 T 28-03-2018 IPR002864 Acyl-ACP thioesterase GO:0006633|GO:0016790 CDW54_RS01740 f6b98839d659a16c12672344100cd143 97 PIRSF PIRSF034852 1 96 3.0E-32 T 28-03-2018 IPR008326 Uncharacterised conserved protein UCP034852 CDW54_RS01740 f6b98839d659a16c12672344100cd143 97 Gene3D G3DSA:2.60.300.12 1 97 9.8E-8 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CDW54_RS01740 f6b98839d659a16c12672344100cd143 97 SUPERFAMILY SSF89360 1 95 1.61E-7 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CDW54_RS03330 705b81d95a0a349ef15c3ba1b6ec04c3 209 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 4 209 4.7E-92 T 28-03-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CDW54_RS03330 705b81d95a0a349ef15c3ba1b6ec04c3 209 SUPERFAMILY SSF53271 5 207 1.27E-74 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CDW54_RS03330 705b81d95a0a349ef15c3ba1b6ec04c3 209 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 3 209 48.948 T 28-03-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CDW54_RS03330 705b81d95a0a349ef15c3ba1b6ec04c3 209 Pfam PF14681 Uracil phosphoribosyltransferase 6 208 1.2E-76 T 28-03-2018 CDW54_RS03330 705b81d95a0a349ef15c3ba1b6ec04c3 209 Gene3D G3DSA:3.40.50.2020 3 207 2.0E-68 T 28-03-2018 CDW54_RS02045 9ba7918908a071a1eb6bdf331fde0dbd 413 Gene3D G3DSA:3.30.1330.20 216 325 9.4E-46 T 28-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 CDW54_RS02045 9ba7918908a071a1eb6bdf331fde0dbd 413 PRINTS PR00423 Cell division protein FtsZ signature 99 119 1.2E-51 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CDW54_RS02045 9ba7918908a071a1eb6bdf331fde0dbd 413 PRINTS PR00423 Cell division protein FtsZ signature 190 212 1.2E-51 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CDW54_RS02045 9ba7918908a071a1eb6bdf331fde0dbd 413 PRINTS PR00423 Cell division protein FtsZ signature 213 234 1.2E-51 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CDW54_RS02045 9ba7918908a071a1eb6bdf331fde0dbd 413 PRINTS PR00423 Cell division protein FtsZ signature 127 148 1.2E-51 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CDW54_RS02045 9ba7918908a071a1eb6bdf331fde0dbd 413 SUPERFAMILY SSF52490 14 209 2.35E-69 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CDW54_RS02045 9ba7918908a071a1eb6bdf331fde0dbd 413 Pfam PF12327 FtsZ family, C-terminal domain 223 317 4.9E-32 T 28-03-2018 IPR024757 Cell division protein FtsZ, C-terminal CDW54_RS02045 9ba7918908a071a1eb6bdf331fde0dbd 413 Gene3D G3DSA:3.40.50.1440 9 215 1.1E-42 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CDW54_RS02045 9ba7918908a071a1eb6bdf331fde0dbd 413 SMART SM00864 14 206 7.3E-116 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CDW54_RS02045 9ba7918908a071a1eb6bdf331fde0dbd 413 SUPERFAMILY SSF55307 205 319 1.4E-43 T 28-03-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 CDW54_RS02045 9ba7918908a071a1eb6bdf331fde0dbd 413 ProSitePatterns PS01134 FtsZ protein signature 1. 45 79 - T 28-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 CDW54_RS02045 9ba7918908a071a1eb6bdf331fde0dbd 413 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 15 174 2.4E-40 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CDW54_RS02045 9ba7918908a071a1eb6bdf331fde0dbd 413 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 10 333 3.2E-131 T 28-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 CDW54_RS02045 9ba7918908a071a1eb6bdf331fde0dbd 413 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 10 404 38.692 T 28-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 CDW54_RS02045 9ba7918908a071a1eb6bdf331fde0dbd 413 ProSitePatterns PS01135 FtsZ protein signature 2. 98 119 - T 28-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 CDW54_RS02045 9ba7918908a071a1eb6bdf331fde0dbd 413 SMART SM00865 208 325 2.9E-54 T 28-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 CDW54_RS05230 a0a68cac3d1920b1712376a3c8ada309 298 Gene3D G3DSA:3.30.565.10 140 296 8.9E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS05230 a0a68cac3d1920b1712376a3c8ada309 298 PRINTS PR01780 Lantibiotic regulatory protein signature 89 105 2.8E-6 T 28-03-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 CDW54_RS05230 a0a68cac3d1920b1712376a3c8ada309 298 PRINTS PR01780 Lantibiotic regulatory protein signature 249 264 2.8E-6 T 28-03-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 CDW54_RS05230 a0a68cac3d1920b1712376a3c8ada309 298 PRINTS PR01780 Lantibiotic regulatory protein signature 187 202 2.8E-6 T 28-03-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 CDW54_RS05230 a0a68cac3d1920b1712376a3c8ada309 298 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 192 291 2.5E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS05230 a0a68cac3d1920b1712376a3c8ada309 298 SUPERFAMILY SSF55874 155 282 7.53E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS05230 a0a68cac3d1920b1712376a3c8ada309 298 SMART SM00388 80 145 3.5E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDW54_RS05230 a0a68cac3d1920b1712376a3c8ada309 298 Gene3D G3DSA:1.10.287.130 59 139 1.2E-14 T 28-03-2018 CDW54_RS05230 a0a68cac3d1920b1712376a3c8ada309 298 Pfam PF00512 His Kinase A (phospho-acceptor) domain 87 144 1.1E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDW54_RS05230 a0a68cac3d1920b1712376a3c8ada309 298 SUPERFAMILY SSF47384 74 145 5.3E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDW54_RS05230 a0a68cac3d1920b1712376a3c8ada309 298 SMART SM00387 191 297 9.0E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS03060 1a72b8e93f302d9042163bb3603d8d5c 204 Gene3D G3DSA:3.40.50.10490 4 203 1.2E-19 T 28-03-2018 CDW54_RS03060 1a72b8e93f302d9042163bb3603d8d5c 204 Pfam PF13580 SIS domain 5 129 3.6E-10 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CDW54_RS03060 1a72b8e93f302d9042163bb3603d8d5c 204 SUPERFAMILY SSF53697 8 188 5.34E-12 T 28-03-2018 CDW54_RS00045 3b224322135a78d369fd28a104f3e493 1240 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1045 1225 3.8E-6 T 28-03-2018 CDW54_RS00045 3b224322135a78d369fd28a104f3e493 1240 Pfam PF13361 UvrD-like helicase C-terminal domain 471 881 2.7E-31 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CDW54_RS00045 3b224322135a78d369fd28a104f3e493 1240 Gene3D G3DSA:1.10.486.10 622 774 1.2E-37 T 28-03-2018 CDW54_RS00045 3b224322135a78d369fd28a104f3e493 1240 Hamap MF_01451 ATP-dependent helicase/nuclease subunit A [addA]. 10 1238 18.791 T 28-03-2018 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 CDW54_RS00045 3b224322135a78d369fd28a104f3e493 1240 TIGRFAM TIGR02785 addA_Gpos: helicase-exonuclease AddAB, AddA subunit 13 1237 0.0 T 28-03-2018 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 CDW54_RS00045 3b224322135a78d369fd28a104f3e493 1240 Gene3D G3DSA:3.90.320.10 998 1236 1.3E-33 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CDW54_RS00045 3b224322135a78d369fd28a104f3e493 1240 Gene3D G3DSA:3.40.50.300 475 621 1.6E-16 T 28-03-2018 CDW54_RS00045 3b224322135a78d369fd28a104f3e493 1240 SUPERFAMILY SSF52540 344 550 8.38E-115 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS00045 3b224322135a78d369fd28a104f3e493 1240 SUPERFAMILY SSF52540 6 203 8.38E-115 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS00045 3b224322135a78d369fd28a104f3e493 1240 SUPERFAMILY SSF52540 579 815 8.38E-115 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS00045 3b224322135a78d369fd28a104f3e493 1240 SUPERFAMILY SSF52540 860 886 8.38E-115 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS00045 3b224322135a78d369fd28a104f3e493 1240 SUPERFAMILY SSF52980 1008 1225 1.07E-23 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CDW54_RS00045 3b224322135a78d369fd28a104f3e493 1240 Pfam PF00580 UvrD/REP helicase N-terminal domain 14 462 1.2E-74 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CDW54_RS00045 3b224322135a78d369fd28a104f3e493 1240 Gene3D G3DSA:3.40.50.300 6 474 1.3E-52 T 28-03-2018 CDW54_RS06560 a6d79a0788afa5cb06366bd3b19a8895 581 Pfam PF03109 ABC1 family 90 207 9.2E-32 T 28-03-2018 IPR004147 UbiB domain CDW54_RS06560 a6d79a0788afa5cb06366bd3b19a8895 581 Gene3D G3DSA:3.30.200.20 79 219 1.9E-19 T 28-03-2018 CDW54_RS06560 a6d79a0788afa5cb06366bd3b19a8895 581 Gene3D G3DSA:1.10.510.10 220 393 1.1E-4 T 28-03-2018 CDW54_RS06560 a6d79a0788afa5cb06366bd3b19a8895 581 SUPERFAMILY SSF56112 170 281 4.65E-25 T 28-03-2018 IPR011009 Protein kinase-like domain CDW54_RS06560 a6d79a0788afa5cb06366bd3b19a8895 581 SUPERFAMILY SSF56112 72 135 4.65E-25 T 28-03-2018 IPR011009 Protein kinase-like domain CDW54_RS06560 a6d79a0788afa5cb06366bd3b19a8895 581 SUPERFAMILY SSF56112 315 453 4.65E-25 T 28-03-2018 IPR011009 Protein kinase-like domain CDW54_RS12695 4c1c43b6a8a83d5108445a9cb3edf403 166 SMART SM00116 23 71 5.1 T 28-03-2018 IPR000644 CBS domain CDW54_RS12695 4c1c43b6a8a83d5108445a9cb3edf403 166 SMART SM00116 93 139 0.067 T 28-03-2018 IPR000644 CBS domain CDW54_RS12695 4c1c43b6a8a83d5108445a9cb3edf403 166 SUPERFAMILY SSF54631 17 138 2.44E-28 T 28-03-2018 CDW54_RS12695 4c1c43b6a8a83d5108445a9cb3edf403 166 Gene3D G3DSA:3.10.580.10 6 153 1.7E-19 T 28-03-2018 CDW54_RS12695 4c1c43b6a8a83d5108445a9cb3edf403 166 Pfam PF00571 CBS domain 44 70 0.0019 T 28-03-2018 IPR000644 CBS domain CDW54_RS12695 4c1c43b6a8a83d5108445a9cb3edf403 166 Pfam PF00571 CBS domain 86 138 1.8E-8 T 28-03-2018 IPR000644 CBS domain CDW54_RS09855 17c5ee045e15d49071aae355f5b9746e 312 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 3 263 4.4E-114 T 28-03-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 CDW54_RS09855 17c5ee045e15d49071aae355f5b9746e 312 SUPERFAMILY SSF53448 1 275 7.93E-67 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDW54_RS09855 17c5ee045e15d49071aae355f5b9746e 312 Gene3D G3DSA:3.90.550.10 1 276 2.4E-60 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDW54_RS09855 17c5ee045e15d49071aae355f5b9746e 312 Pfam PF00483 Nucleotidyl transferase 5 257 1.5E-34 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CDW54_RS10190 199df1a7bd416bdad6806342a01f5993 929 SUPERFAMILY SSF53098 3 207 5.43E-56 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS10190 199df1a7bd416bdad6806342a01f5993 929 Gene3D G3DSA:3.40.50.300 253 678 4.4E-17 T 28-03-2018 CDW54_RS10190 199df1a7bd416bdad6806342a01f5993 929 SMART SM00491 756 889 6.3E-35 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CDW54_RS10190 199df1a7bd416bdad6806342a01f5993 929 Gene3D G3DSA:3.40.50.300 718 928 2.7E-10 T 28-03-2018 CDW54_RS10190 199df1a7bd416bdad6806342a01f5993 929 Pfam PF00929 Exonuclease 8 161 9.4E-29 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CDW54_RS10190 199df1a7bd416bdad6806342a01f5993 929 SUPERFAMILY SSF52540 859 880 1.06E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS10190 199df1a7bd416bdad6806342a01f5993 929 SUPERFAMILY SSF52540 730 828 1.06E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS10190 199df1a7bd416bdad6806342a01f5993 929 SUPERFAMILY SSF52540 409 508 1.06E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS10190 199df1a7bd416bdad6806342a01f5993 929 SUPERFAMILY SSF52540 249 349 3.02E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS10190 199df1a7bd416bdad6806342a01f5993 929 SUPERFAMILY SSF52540 425 480 3.02E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS10190 199df1a7bd416bdad6806342a01f5993 929 SUPERFAMILY SSF52540 848 884 3.02E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS10190 199df1a7bd416bdad6806342a01f5993 929 TIGRFAM TIGR01407 dinG_rel: putative DnaQ family exonuclease/DinG family helicase 5 922 4.0E-285 T 28-03-2018 IPR006310 DnaQ exonuclease/DinG helicase, predicted CDW54_RS10190 199df1a7bd416bdad6806342a01f5993 929 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 4 176 4.1E-28 T 28-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDW54_RS10190 199df1a7bd416bdad6806342a01f5993 929 Gene3D G3DSA:3.30.420.10 2 174 3.5E-40 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS10190 199df1a7bd416bdad6806342a01f5993 929 Pfam PF04851 Type III restriction enzyme, res subunit 256 471 2.1E-6 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CDW54_RS10190 199df1a7bd416bdad6806342a01f5993 929 Pfam PF13307 Helicase C-terminal domain 742 902 7.3E-36 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CDW54_RS10190 199df1a7bd416bdad6806342a01f5993 929 SMART SM00479 5 171 5.2E-37 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CDW54_RS00965 bef10fd596069556e61636be69f172a6 203 PIRSF PIRSF037778 2 193 1.1E-62 T 28-03-2018 IPR025720 ECF transporter, Riboflavin transporter RibU GO:0005886|GO:0032217|GO:0032218 CDW54_RS00965 bef10fd596069556e61636be69f172a6 203 Pfam PF12822 ECF transporter, substrate-specific component 7 180 5.1E-26 T 28-03-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 CDW54_RS01080 e19ecdc157b07d9d346ea9d7c3779851 384 SUPERFAMILY SSF53901 2 166 3.74E-40 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDW54_RS01080 e19ecdc157b07d9d346ea9d7c3779851 384 SUPERFAMILY SSF53901 169 383 2.27E-64 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDW54_RS01080 e19ecdc157b07d9d346ea9d7c3779851 384 Gene3D G3DSA:3.40.47.10 20 169 9.4E-13 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDW54_RS01080 e19ecdc157b07d9d346ea9d7c3779851 384 Pfam PF08540 Hydroxymethylglutaryl-coenzyme A synthase C terminal 256 352 4.0E-14 T 28-03-2018 IPR013746 Hydroxymethylglutaryl-coenzyme A synthase C-terminal domain GO:0004421|GO:0008299 KEGG: 00072+2.3.3.10|KEGG: 00280+2.3.3.10|KEGG: 00650+2.3.3.10|KEGG: 00900+2.3.3.10|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7571|MetaCyc: PWY-922|Reactome: R-HSA-1989781 CDW54_RS01080 e19ecdc157b07d9d346ea9d7c3779851 384 Pfam PF08540 Hydroxymethylglutaryl-coenzyme A synthase C terminal 180 252 2.9E-11 T 28-03-2018 IPR013746 Hydroxymethylglutaryl-coenzyme A synthase C-terminal domain GO:0004421|GO:0008299 KEGG: 00072+2.3.3.10|KEGG: 00280+2.3.3.10|KEGG: 00650+2.3.3.10|KEGG: 00900+2.3.3.10|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7571|MetaCyc: PWY-922|Reactome: R-HSA-1989781 CDW54_RS01080 e19ecdc157b07d9d346ea9d7c3779851 384 Pfam PF01154 Hydroxymethylglutaryl-coenzyme A synthase N terminal 2 164 1.8E-22 T 28-03-2018 IPR013528 Hydroxymethylglutaryl-coenzyme A synthase, N-terminal GO:0004421|GO:0008299 Reactome: R-HSA-1989781 CDW54_RS01080 e19ecdc157b07d9d346ea9d7c3779851 384 Gene3D G3DSA:3.40.47.10 175 319 8.7E-48 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDW54_RS01080 e19ecdc157b07d9d346ea9d7c3779851 384 TIGRFAM TIGR01835 HMG-CoA-S_prok: hydroxymethylglutaryl-CoA synthase 3 382 3.7E-160 T 28-03-2018 IPR011554 Hydroxymethylglutaryl-CoA synthase, prokaryotic KEGG: 00072+2.3.3.10|KEGG: 00280+2.3.3.10|KEGG: 00650+2.3.3.10|KEGG: 00900+2.3.3.10|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7571|MetaCyc: PWY-922 CDW54_RS06685 31f19e5a6ace3876a437cb6bf84077e1 126 PRINTS PR01853 Bacterial YajC preprotein translocase signature 41 59 4.3E-6 T 28-03-2018 IPR003849 Preprotein translocase YajC CDW54_RS06685 31f19e5a6ace3876a437cb6bf84077e1 126 PRINTS PR01853 Bacterial YajC preprotein translocase signature 3 23 4.3E-6 T 28-03-2018 IPR003849 Preprotein translocase YajC CDW54_RS06685 31f19e5a6ace3876a437cb6bf84077e1 126 Pfam PF02699 Preprotein translocase subunit 6 81 8.1E-23 T 28-03-2018 IPR003849 Preprotein translocase YajC CDW54_RS06685 31f19e5a6ace3876a437cb6bf84077e1 126 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 6 83 3.3E-18 T 28-03-2018 IPR003849 Preprotein translocase YajC CDW54_RS06685 31f19e5a6ace3876a437cb6bf84077e1 126 SMART SM01323 2 84 1.0E-29 T 28-03-2018 IPR003849 Preprotein translocase YajC CDW54_RS10355 0a793a73f4149ef47216e0d8b5dde515 578 SMART SM00387 468 578 5.2E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS10355 0a793a73f4149ef47216e0d8b5dde515 578 Pfam PF00512 His Kinase A (phospho-acceptor) domain 360 425 3.6E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDW54_RS10355 0a793a73f4149ef47216e0d8b5dde515 578 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 470 577 3.7E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS10355 0a793a73f4149ef47216e0d8b5dde515 578 SMART SM00388 359 426 2.9E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDW54_RS10355 0a793a73f4149ef47216e0d8b5dde515 578 SUPERFAMILY SSF55874 420 577 1.03E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS10355 0a793a73f4149ef47216e0d8b5dde515 578 PRINTS PR00344 Bacterial sensor protein C-terminal signature 504 518 1.6E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDW54_RS10355 0a793a73f4149ef47216e0d8b5dde515 578 PRINTS PR00344 Bacterial sensor protein C-terminal signature 539 557 1.6E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDW54_RS10355 0a793a73f4149ef47216e0d8b5dde515 578 PRINTS PR00344 Bacterial sensor protein C-terminal signature 563 576 1.6E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDW54_RS10355 0a793a73f4149ef47216e0d8b5dde515 578 PRINTS PR00344 Bacterial sensor protein C-terminal signature 522 532 1.6E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDW54_RS10355 0a793a73f4149ef47216e0d8b5dde515 578 Gene3D G3DSA:3.30.450.20 231 356 5.0E-6 T 28-03-2018 CDW54_RS10355 0a793a73f4149ef47216e0d8b5dde515 578 SUPERFAMILY SSF47384 348 424 9.81E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDW54_RS10355 0a793a73f4149ef47216e0d8b5dde515 578 Gene3D G3DSA:3.30.565.10 428 578 1.8E-39 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS10355 0a793a73f4149ef47216e0d8b5dde515 578 Gene3D G3DSA:3.30.450.20 29 159 2.4E-22 T 28-03-2018 CDW54_RS10355 0a793a73f4149ef47216e0d8b5dde515 578 Pfam PF16736 Single Cache-like 34 152 1.2E-33 T 28-03-2018 IPR031967 PhoR, single Cache-like domain CDW54_RS10355 0a793a73f4149ef47216e0d8b5dde515 578 Gene3D G3DSA:1.10.287.130 357 422 9.7E-15 T 28-03-2018 CDW54_RS01840 526f5f4fb42810a0acdf769529bb09d6 528 Pfam PF13489 Methyltransferase domain 18 172 1.7E-16 T 28-03-2018 CDW54_RS01840 526f5f4fb42810a0acdf769529bb09d6 528 SUPERFAMILY SSF53335 15 180 1.49E-25 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDW54_RS01840 526f5f4fb42810a0acdf769529bb09d6 528 Gene3D G3DSA:3.40.50.150 15 494 8.2E-24 T 28-03-2018 CDW54_RS05575 3f7723555bd31651e5fb06344896cf82 255 PIRSF PIRSF009320 2 72 8.6E-16 T 28-03-2018 CDW54_RS05575 3f7723555bd31651e5fb06344896cf82 255 PIRSF PIRSF009320 90 255 2.4E-6 T 28-03-2018 CDW54_RS05575 3f7723555bd31651e5fb06344896cf82 255 Gene3D G3DSA:3.40.50.300 1 255 2.8E-65 T 28-03-2018 CDW54_RS05575 3f7723555bd31651e5fb06344896cf82 255 SUPERFAMILY SSF52540 1 253 1.15E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS05575 3f7723555bd31651e5fb06344896cf82 255 Pfam PF13614 AAA domain 3 178 7.8E-69 T 28-03-2018 IPR025669 AAA domain CDW54_RS06060 233bb1d23c773d6626abf34d98b50ec8 279 TIGRFAM TIGR04520 ECF_ATPase_1: energy-coupling factor transporter ATPase 5 273 2.1E-119 T 28-03-2018 IPR030947 Energy-coupling factor transporter ATP-binding protein EcfA1 CDW54_RS06060 233bb1d23c773d6626abf34d98b50ec8 279 SUPERFAMILY SSF52540 3 230 2.59E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS06060 233bb1d23c773d6626abf34d98b50ec8 279 Gene3D G3DSA:3.40.50.300 1 265 4.6E-69 T 28-03-2018 CDW54_RS06060 233bb1d23c773d6626abf34d98b50ec8 279 Pfam PF00005 ABC transporter 23 169 6.1E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS06060 233bb1d23c773d6626abf34d98b50ec8 279 SMART SM00382 32 217 3.4E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS05160 17e8cdaf18a9f29d227c5804dfb6b7c5 492 SUPERFAMILY SSF52540 302 484 9.55E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS05160 17e8cdaf18a9f29d227c5804dfb6b7c5 492 Pfam PF12848 ABC transporter 170 235 1.8E-5 T 28-03-2018 IPR032781 ABC-transporter extension domain CDW54_RS05160 17e8cdaf18a9f29d227c5804dfb6b7c5 492 Pfam PF00005 ABC transporter 25 65 5.8E-10 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS05160 17e8cdaf18a9f29d227c5804dfb6b7c5 492 Pfam PF00005 ABC transporter 315 438 1.1E-16 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS05160 17e8cdaf18a9f29d227c5804dfb6b7c5 492 ProSitePatterns PS00211 ABC transporters family signature. 410 424 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS05160 17e8cdaf18a9f29d227c5804dfb6b7c5 492 SUPERFAMILY SSF52540 4 201 5.27E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS05160 17e8cdaf18a9f29d227c5804dfb6b7c5 492 Gene3D G3DSA:3.40.50.300 260 490 2.2E-37 T 28-03-2018 CDW54_RS05160 17e8cdaf18a9f29d227c5804dfb6b7c5 492 SMART SM00382 30 176 5.7E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS05160 17e8cdaf18a9f29d227c5804dfb6b7c5 492 SMART SM00382 322 482 8.5E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS05160 17e8cdaf18a9f29d227c5804dfb6b7c5 492 Gene3D G3DSA:3.40.50.300 2 259 1.4E-42 T 28-03-2018 CDW54_RS00310 01296152b7977bf25b7ca3e0394a4853 547 Pfam PF02817 e3 binding domain 233 268 7.2E-15 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CDW54_RS00310 01296152b7977bf25b7ca3e0394a4853 547 Gene3D G3DSA:2.40.50.100 149 197 5.6E-9 T 28-03-2018 CDW54_RS00310 01296152b7977bf25b7ca3e0394a4853 547 Gene3D G3DSA:3.30.559.10 303 545 1.0E-87 T 28-03-2018 CDW54_RS00310 01296152b7977bf25b7ca3e0394a4853 547 Gene3D G3DSA:4.10.320.10 224 302 1.1E-20 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CDW54_RS00310 01296152b7977bf25b7ca3e0394a4853 547 SUPERFAMILY SSF51230 118 211 1.44E-26 T 28-03-2018 IPR011053 Single hybrid motif CDW54_RS00310 01296152b7977bf25b7ca3e0394a4853 547 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CDW54_RS00310 01296152b7977bf25b7ca3e0394a4853 547 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 316 545 1.7E-86 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CDW54_RS00310 01296152b7977bf25b7ca3e0394a4853 547 SUPERFAMILY SSF51230 1 93 4.97E-26 T 28-03-2018 IPR011053 Single hybrid motif CDW54_RS00310 01296152b7977bf25b7ca3e0394a4853 547 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 143 172 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CDW54_RS00310 01296152b7977bf25b7ca3e0394a4853 547 Pfam PF00364 Biotin-requiring enzyme 4 76 3.3E-23 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CDW54_RS00310 01296152b7977bf25b7ca3e0394a4853 547 Pfam PF00364 Biotin-requiring enzyme 120 192 3.4E-23 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CDW54_RS00310 01296152b7977bf25b7ca3e0394a4853 547 SUPERFAMILY SSF47005 227 272 1.83E-13 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CDW54_RS00310 01296152b7977bf25b7ca3e0394a4853 547 Gene3D G3DSA:3.90.1170.30 2 45 4.5E-12 T 28-03-2018 CDW54_RS00310 01296152b7977bf25b7ca3e0394a4853 547 Gene3D G3DSA:3.90.1170.30 46 148 1.2E-22 T 28-03-2018 CDW54_RS00310 01296152b7977bf25b7ca3e0394a4853 547 SUPERFAMILY SSF52777 310 545 3.47E-85 T 28-03-2018 CDW54_RS03875 f10c9526c50a29ed2eadb0968e0bd50c 50 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 2 50 15.793 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS03875 f10c9526c50a29ed2eadb0968e0bd50c 50 Pfam PF00471 Ribosomal protein L33 5 50 1.4E-16 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS03875 f10c9526c50a29ed2eadb0968e0bd50c 50 SUPERFAMILY SSF57829 4 50 3.66E-14 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CDW54_RS03875 f10c9526c50a29ed2eadb0968e0bd50c 50 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 50 7.5E-15 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS05895 055abd53bf98011213a466cc643727af 137 Pfam PF00164 Ribosomal protein S12/S23 32 136 3.4E-36 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS05895 055abd53bf98011213a466cc643727af 137 ProSitePatterns PS00055 Ribosomal protein S12 signature. 56 63 - T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS05895 055abd53bf98011213a466cc643727af 137 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 137 2.2E-67 T 28-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS05895 055abd53bf98011213a466cc643727af 137 SUPERFAMILY SSF50249 2 136 7.45E-47 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDW54_RS05895 055abd53bf98011213a466cc643727af 137 Gene3D G3DSA:2.40.50.140 1 137 5.1E-62 T 28-03-2018 CDW54_RS05895 055abd53bf98011213a466cc643727af 137 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 136 39.327 T 28-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS05895 055abd53bf98011213a466cc643727af 137 PIRSF PIRSF002133 1 137 1.9E-47 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS05895 055abd53bf98011213a466cc643727af 137 PRINTS PR01034 Ribosomal protein S12 signature 40 55 6.5E-57 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS05895 055abd53bf98011213a466cc643727af 137 PRINTS PR01034 Ribosomal protein S12 signature 107 123 6.5E-57 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS05895 055abd53bf98011213a466cc643727af 137 PRINTS PR01034 Ribosomal protein S12 signature 90 107 6.5E-57 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS05895 055abd53bf98011213a466cc643727af 137 PRINTS PR01034 Ribosomal protein S12 signature 71 90 6.5E-57 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS05895 055abd53bf98011213a466cc643727af 137 PRINTS PR01034 Ribosomal protein S12 signature 55 70 6.5E-57 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS05895 055abd53bf98011213a466cc643727af 137 PRINTS PR01034 Ribosomal protein S12 signature 123 135 6.5E-57 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS04415 d9555c0107f64642a75240b0419172d3 717 Pfam PF07971 Glycosyl hydrolase family 92 205 696 4.0E-141 T 28-03-2018 IPR012939 Glycosyl hydrolase family 92 CDW54_RS04415 d9555c0107f64642a75240b0419172d3 717 Gene3D G3DSA:1.20.1050.60 310 404 3.7E-22 T 28-03-2018 CDW54_RS04415 d9555c0107f64642a75240b0419172d3 717 Gene3D G3DSA:2.70.98.10 3 285 4.0E-44 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CDW54_RS04415 d9555c0107f64642a75240b0419172d3 717 SUPERFAMILY SSF48208 225 653 7.65E-30 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CDW54_RS04415 d9555c0107f64642a75240b0419172d3 717 Gene3D G3DSA:1.20.1610.10 405 575 2.8E-52 T 28-03-2018 CDW54_RS04415 d9555c0107f64642a75240b0419172d3 717 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 19 696 2.2E-143 T 28-03-2018 IPR005887 Alpha-1,2-mannosidase, putative CDW54_RS00265 856f52c29842045d3e335fc645df0711 374 Pfam PF14504 CAP-associated N-terminal 60 202 9.6E-41 T 28-03-2018 IPR029410 CAP-associated domain CDW54_RS12270 224f5af8cdc8cb6e8e54ee3de2deed99 78 Gene3D G3DSA:2.10.260.10 1 77 2.6E-9 T 28-03-2018 CDW54_RS12270 224f5af8cdc8cb6e8e54ee3de2deed99 78 SUPERFAMILY SSF89447 7 55 5.06E-6 T 28-03-2018 CDW54_RS12270 224f5af8cdc8cb6e8e54ee3de2deed99 78 TIGRFAM TIGR02609 doc_partner: putative addiction module antidote 7 77 5.1E-26 T 28-03-2018 IPR013432 Putative addiction module antidote CDW54_RS03745 5ead70c39f5cd4c0fbdf54fb5a57a45d 575 Gene3D G3DSA:1.10.3720.10 19 285 7.1E-35 T 28-03-2018 CDW54_RS03745 5ead70c39f5cd4c0fbdf54fb5a57a45d 575 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 323 565 5.0E-62 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CDW54_RS03745 5ead70c39f5cd4c0fbdf54fb5a57a45d 575 Gene3D G3DSA:3.40.190.10 322 412 1.0E-13 T 28-03-2018 CDW54_RS03745 5ead70c39f5cd4c0fbdf54fb5a57a45d 575 SUPERFAMILY SSF161098 88 274 2.09E-40 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS03745 5ead70c39f5cd4c0fbdf54fb5a57a45d 575 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 277 3.4E-25 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS03745 5ead70c39f5cd4c0fbdf54fb5a57a45d 575 SUPERFAMILY SSF53850 318 574 8.31E-82 T 28-03-2018 CDW54_RS03745 5ead70c39f5cd4c0fbdf54fb5a57a45d 575 Gene3D G3DSA:3.40.190.100 413 526 2.3E-36 T 28-03-2018 CDW54_RS02400 128d9f27d5bb71c9f64ad8fc57b963e0 121 Pfam PF10710 Protein of unknown function (DUF2512) 1 111 7.9E-27 T 28-03-2018 IPR019649 Protein of unknown function DUF2512 CDW54_RS10765 609f02cc2537cc31e1217d79ca06b571 154 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 15 144 8.9E-37 T 28-03-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 CDW54_RS10765 609f02cc2537cc31e1217d79ca06b571 154 Gene3D G3DSA:3.40.630.30 3 154 2.0E-24 T 28-03-2018 CDW54_RS10765 609f02cc2537cc31e1217d79ca06b571 154 SUPERFAMILY SSF55729 22 149 1.24E-22 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDW54_RS10765 609f02cc2537cc31e1217d79ca06b571 154 Pfam PF00583 Acetyltransferase (GNAT) family 26 120 4.6E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CDW54_RS07600 1c05866c49a34f9ee92376f22904b9f3 157 Gene3D G3DSA:1.10.1660.10 5 155 5.5E-15 T 28-03-2018 CDW54_RS07600 1c05866c49a34f9ee92376f22904b9f3 157 ProSitePatterns PS00552 MerR-type HTH domain signature. 20 42 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CDW54_RS07600 1c05866c49a34f9ee92376f22904b9f3 157 Pfam PF13411 MerR HTH family regulatory protein 19 81 9.2E-11 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CDW54_RS07600 1c05866c49a34f9ee92376f22904b9f3 157 SUPERFAMILY SSF46955 19 115 3.57E-16 T 28-03-2018 IPR009061 Putative DNA-binding domain CDW54_RS07600 1c05866c49a34f9ee92376f22904b9f3 157 SMART SM00422 19 86 8.8E-5 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CDW54_RS01075 65a41647c6e5222566c66de22e48ce54 813 Pfam PF00108 Thiolase, N-terminal domain 4 256 7.9E-91 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CDW54_RS01075 65a41647c6e5222566c66de22e48ce54 813 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 84 102 - T 28-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CDW54_RS01075 65a41647c6e5222566c66de22e48ce54 813 Pfam PF00368 Hydroxymethylglutaryl-coenzyme A reductase 407 771 3.2E-107 T 28-03-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CDW54_RS01075 65a41647c6e5222566c66de22e48ce54 813 Pfam PF02803 Thiolase, C-terminal domain 266 385 9.5E-45 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CDW54_RS01075 65a41647c6e5222566c66de22e48ce54 813 ProSitePatterns PS00737 Thiolases signature 2. 333 349 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CDW54_RS01075 65a41647c6e5222566c66de22e48ce54 813 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 385 3.0E-142 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CDW54_RS01075 65a41647c6e5222566c66de22e48ce54 813 SUPERFAMILY SSF55035 497 606 3.79E-30 T 28-03-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CDW54_RS01075 65a41647c6e5222566c66de22e48ce54 813 SUPERFAMILY SSF53901 3 264 1.9E-75 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDW54_RS01075 65a41647c6e5222566c66de22e48ce54 813 ProSitePatterns PS00099 Thiolases active site. 368 381 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CDW54_RS01075 65a41647c6e5222566c66de22e48ce54 813 TIGRFAM TIGR00532 HMG_CoA_R_NAD: hydroxymethylglutaryl-CoA reductase, degradative 396 770 1.1E-98 T 28-03-2018 IPR004553 Hydroxymethylglutaryl-CoA reductase, bacterial-type GO:0015936|GO:0016616|GO:0050662 CDW54_RS01075 65a41647c6e5222566c66de22e48ce54 813 Gene3D G3DSA:3.90.770.10 394 509 1.8E-21 T 28-03-2018 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CDW54_RS01075 65a41647c6e5222566c66de22e48ce54 813 SUPERFAMILY SSF53901 266 385 1.62E-37 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDW54_RS01075 65a41647c6e5222566c66de22e48ce54 813 SUPERFAMILY SSF56542 615 812 1.7E-96 T 28-03-2018 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CDW54_RS01075 65a41647c6e5222566c66de22e48ce54 813 SUPERFAMILY SSF56542 398 505 1.7E-96 T 28-03-2018 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CDW54_RS01075 65a41647c6e5222566c66de22e48ce54 813 ProSitePatterns PS01192 Hydroxymethylglutaryl-coenzyme A reductases signature 3. 756 769 - T 28-03-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CDW54_RS01075 65a41647c6e5222566c66de22e48ce54 813 Gene3D G3DSA:3.40.47.10 261 384 6.3E-27 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDW54_RS01075 65a41647c6e5222566c66de22e48ce54 813 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 559 577 2.7E-10 T 28-03-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CDW54_RS01075 65a41647c6e5222566c66de22e48ce54 813 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 439 460 2.7E-10 T 28-03-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CDW54_RS01075 65a41647c6e5222566c66de22e48ce54 813 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 698 719 2.7E-10 T 28-03-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CDW54_RS01075 65a41647c6e5222566c66de22e48ce54 813 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 466 486 2.7E-10 T 28-03-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CDW54_RS01075 65a41647c6e5222566c66de22e48ce54 813 Gene3D G3DSA:3.90.770.10 604 775 6.9E-34 T 28-03-2018 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CDW54_RS01075 65a41647c6e5222566c66de22e48ce54 813 Gene3D G3DSA:3.40.47.10 1 260 7.2E-56 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDW54_RS01075 65a41647c6e5222566c66de22e48ce54 813 Gene3D G3DSA:3.30.70.420 510 603 2.2E-29 T 28-03-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CDW54_RS04225 c4bdd584b2407b2757b0a148f24f7bca 314 Pfam PF01966 HD domain 160 279 3.5E-10 T 28-03-2018 IPR006674 HD domain CDW54_RS04225 c4bdd584b2407b2757b0a148f24f7bca 314 SMART SM00471 155 289 2.5E-4 T 28-03-2018 IPR003607 HD/PDEase domain CDW54_RS04225 c4bdd584b2407b2757b0a148f24f7bca 314 Pfam PF01336 OB-fold nucleic acid binding domain 25 87 1.1E-6 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CDW54_RS04225 c4bdd584b2407b2757b0a148f24f7bca 314 SUPERFAMILY SSF109604 138 280 1.95E-12 T 28-03-2018 CDW54_RS04225 c4bdd584b2407b2757b0a148f24f7bca 314 Gene3D G3DSA:1.10.3210.10 132 301 2.5E-13 T 28-03-2018 CDW54_RS04225 c4bdd584b2407b2757b0a148f24f7bca 314 Gene3D G3DSA:2.40.50.140 1 96 1.0E-10 T 28-03-2018 CDW54_RS11530 436ff17a42cad9ea717753ea0173d924 611 Pfam PF00009 Elongation factor Tu GTP binding domain 12 190 4.9E-53 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDW54_RS11530 436ff17a42cad9ea717753ea0173d924 611 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CDW54_RS11530 436ff17a42cad9ea717753ea0173d924 611 PRINTS PR00315 GTP-binding elongation factor signature 83 93 4.6E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDW54_RS11530 436ff17a42cad9ea717753ea0173d924 611 PRINTS PR00315 GTP-binding elongation factor signature 99 110 4.6E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDW54_RS11530 436ff17a42cad9ea717753ea0173d924 611 PRINTS PR00315 GTP-binding elongation factor signature 58 66 4.6E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDW54_RS11530 436ff17a42cad9ea717753ea0173d924 611 PRINTS PR00315 GTP-binding elongation factor signature 135 144 4.6E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDW54_RS11530 436ff17a42cad9ea717753ea0173d924 611 PRINTS PR00315 GTP-binding elongation factor signature 15 28 4.6E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDW54_RS11530 436ff17a42cad9ea717753ea0173d924 611 Gene3D G3DSA:3.30.70.870 297 376 1.1E-28 T 28-03-2018 CDW54_RS11530 436ff17a42cad9ea717753ea0173d924 611 SUPERFAMILY SSF54980 408 503 2.69E-25 T 28-03-2018 IPR035647 EF-G domain III/V-like CDW54_RS11530 436ff17a42cad9ea717753ea0173d924 611 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 183 8.3E-18 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CDW54_RS11530 436ff17a42cad9ea717753ea0173d924 611 SUPERFAMILY SSF50447 175 297 1.36E-31 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CDW54_RS11530 436ff17a42cad9ea717753ea0173d924 611 Gene3D G3DSA:3.30.70.240 403 559 1.4E-28 T 28-03-2018 CDW54_RS11530 436ff17a42cad9ea717753ea0173d924 611 Gene3D G3DSA:3.40.50.300 8 194 8.3E-36 T 28-03-2018 CDW54_RS11530 436ff17a42cad9ea717753ea0173d924 611 Pfam PF06421 GTP-binding protein LepA C-terminus 497 603 2.0E-52 T 28-03-2018 IPR013842 GTP-binding protein LepA, C-terminal CDW54_RS11530 436ff17a42cad9ea717753ea0173d924 611 Hamap MF_00071 Elongation factor 4 [lepA]. 1 607 311.552 T 28-03-2018 IPR006297 Elongation factor 4 GO:0005525 CDW54_RS11530 436ff17a42cad9ea717753ea0173d924 611 SUPERFAMILY SSF52540 10 214 2.11E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS11530 436ff17a42cad9ea717753ea0173d924 611 SMART SM00838 410 495 0.0011 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CDW54_RS11530 436ff17a42cad9ea717753ea0173d924 611 SUPERFAMILY SSF54980 301 379 2.01E-19 T 28-03-2018 IPR035647 EF-G domain III/V-like CDW54_RS11530 436ff17a42cad9ea717753ea0173d924 611 Gene3D G3DSA:2.40.30.10 197 296 1.7E-25 T 28-03-2018 CDW54_RS11530 436ff17a42cad9ea717753ea0173d924 611 TIGRFAM TIGR01393 lepA: elongation factor 4 12 605 0.0 T 28-03-2018 IPR006297 Elongation factor 4 GO:0005525 CDW54_RS11530 436ff17a42cad9ea717753ea0173d924 611 Pfam PF03144 Elongation factor Tu domain 2 214 284 4.8E-8 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CDW54_RS11530 436ff17a42cad9ea717753ea0173d924 611 Pfam PF00679 Elongation factor G C-terminus 409 495 1.1E-23 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CDW54_RS04365 c7372ce79bc71254690e0c091aab51f0 227 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 7 202 2.0E-15 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CDW54_RS04365 c7372ce79bc71254690e0c091aab51f0 227 Gene3D G3DSA:3.40.50.1110 2 218 2.4E-27 T 28-03-2018 CDW54_RS04365 c7372ce79bc71254690e0c091aab51f0 227 SUPERFAMILY SSF52266 2 223 1.67E-49 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CDW54_RS05240 8e862ec4b4933281860c1a730cb77ddd 260 Pfam PF12730 ABC-2 family transporter protein 4 191 2.2E-13 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CDW54_RS09020 920e3374823252a88e4f1520fcaa1c3c 188 Pfam PF00583 Acetyltransferase (GNAT) family 51 167 7.1E-14 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CDW54_RS09020 920e3374823252a88e4f1520fcaa1c3c 188 SUPERFAMILY SSF55729 2 185 1.08E-28 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDW54_RS09020 920e3374823252a88e4f1520fcaa1c3c 188 Gene3D G3DSA:3.40.630.30 1 188 1.1E-27 T 28-03-2018 CDW54_RS05810 f4fec798b8a85ca037b04d9ba4cb9039 307 Gene3D G3DSA:3.40.50.300 4 306 1.9E-52 T 28-03-2018 CDW54_RS05810 f4fec798b8a85ca037b04d9ba4cb9039 307 PIRSF PIRSF000545 1 307 2.8E-141 T 28-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CDW54_RS05810 f4fec798b8a85ca037b04d9ba4cb9039 307 SUPERFAMILY SSF52540 1 305 5.67E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS05810 f4fec798b8a85ca037b04d9ba4cb9039 307 Hamap MF_00215 Pantothenate kinase [coaA]. 1 307 153.102 T 28-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CDW54_RS05810 f4fec798b8a85ca037b04d9ba4cb9039 307 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 85 226 3.7E-16 T 28-03-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Reactome: R-HSA-73614 CDW54_RS05810 f4fec798b8a85ca037b04d9ba4cb9039 307 TIGRFAM TIGR00554 panK_bact: pantothenate kinase 7 306 6.9E-110 T 28-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CDW54_RS07470 c33918b32bbcd3d356f86b25d35aa614 131 SUPERFAMILY SSF53062 2 128 1.05E-30 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CDW54_RS07470 c33918b32bbcd3d356f86b25d35aa614 131 Pfam PF03610 PTS system fructose IIA component 5 118 1.7E-20 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CDW54_RS07470 c33918b32bbcd3d356f86b25d35aa614 131 Gene3D G3DSA:3.40.50.510 1 131 8.3E-28 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CDW54_RS07470 c33918b32bbcd3d356f86b25d35aa614 131 TIGRFAM TIGR02364 dha_pts: dihydroxyacetone kinase, phosphotransfer subunit 4 125 1.5E-41 T 28-03-2018 IPR012844 Dihydroxyacetone kinase phosphotransferase subunit, N-terminal domain CDW54_RS11505 cd141dca297fbf2e4b16da3b4223365c 71 Gene3D G3DSA:1.20.120.330 10 70 0.0014 T 28-03-2018 CDW54_RS07955 4fc467c5e4be81131028fe2243e2b549 222 Gene3D G3DSA:3.30.240.20 152 212 5.7E-13 T 28-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain CDW54_RS07955 4fc467c5e4be81131028fe2243e2b549 222 Gene3D G3DSA:3.30.240.20 80 149 4.2E-19 T 28-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain CDW54_RS07955 4fc467c5e4be81131028fe2243e2b549 222 Pfam PF04239 Protein of unknown function (DUF421) 86 189 1.7E-25 T 28-03-2018 IPR007353 Protein of unknown function DUF421 CDW54_RS01830 c6a5d18e62a37b1f36530c47de08aa28 463 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 18 436 3.8E-115 T 28-03-2018 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase CDW54_RS01830 c6a5d18e62a37b1f36530c47de08aa28 463 Pfam PF02397 Bacterial sugar transferase 254 434 1.7E-65 T 28-03-2018 IPR003362 Bacterial sugar transferase CDW54_RS03770 a9aa7c50183be8025e2a476f444ff546 710 Pfam PF07664 Ferrous iron transport protein B C terminus 453 505 5.4E-17 T 28-03-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 CDW54_RS03770 a9aa7c50183be8025e2a476f444ff546 710 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 7 635 2.1E-176 T 28-03-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 CDW54_RS03770 a9aa7c50183be8025e2a476f444ff546 710 Pfam PF07670 Nucleoside recognition 510 638 7.1E-28 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CDW54_RS03770 a9aa7c50183be8025e2a476f444ff546 710 Pfam PF07670 Nucleoside recognition 349 443 2.4E-11 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CDW54_RS03770 a9aa7c50183be8025e2a476f444ff546 710 Pfam PF02421 Ferrous iron transport protein B 2 155 1.3E-66 T 28-03-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 CDW54_RS03770 a9aa7c50183be8025e2a476f444ff546 710 Gene3D G3DSA:3.40.50.300 1 251 4.5E-33 T 28-03-2018 CDW54_RS03770 a9aa7c50183be8025e2a476f444ff546 710 SUPERFAMILY SSF52540 1 163 1.93E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS03770 a9aa7c50183be8025e2a476f444ff546 710 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 3 23 7.7E-5 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CDW54_RS03770 a9aa7c50183be8025e2a476f444ff546 710 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 24 42 7.7E-5 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CDW54_RS10740 e8ea2cf0f15cda0dba940110e247d52b 329 SUPERFAMILY SSF51735 1 328 1.81E-102 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS10740 e8ea2cf0f15cda0dba940110e247d52b 329 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 307 5.2E-63 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS10740 e8ea2cf0f15cda0dba940110e247d52b 329 Gene3D G3DSA:3.90.25.10 165 329 2.1E-43 T 28-03-2018 CDW54_RS10740 e8ea2cf0f15cda0dba940110e247d52b 329 Gene3D G3DSA:3.40.50.720 1 164 2.2E-35 T 28-03-2018 CDW54_RS10740 e8ea2cf0f15cda0dba940110e247d52b 329 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 3 326 4.3E-134 T 28-03-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-70370 CDW54_RS04000 9750dc46a7f8160a9e033ed4851eec6f 235 SUPERFAMILY SSF56784 2 231 1.55E-39 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS04000 9750dc46a7f8160a9e033ed4851eec6f 235 Gene3D G3DSA:3.40.50.1000 1 226 1.5E-32 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS04000 9750dc46a7f8160a9e033ed4851eec6f 235 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 113 126 4.2E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDW54_RS04000 9750dc46a7f8160a9e033ed4851eec6f 235 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 164 184 4.2E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDW54_RS04000 9750dc46a7f8160a9e033ed4851eec6f 235 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 4.2E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDW54_RS04000 9750dc46a7f8160a9e033ed4851eec6f 235 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 65 196 2.5E-17 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDW54_RS04000 9750dc46a7f8160a9e033ed4851eec6f 235 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 202 1.8E-25 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS00040 6f869d1b31497eb9c9604d5d6643faf5 113 Pfam PF01638 HxlR-like helix-turn-helix 20 110 7.3E-25 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type CDW54_RS00040 6f869d1b31497eb9c9604d5d6643faf5 113 Gene3D G3DSA:1.10.10.10 4 112 2.2E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS00040 6f869d1b31497eb9c9604d5d6643faf5 113 SUPERFAMILY SSF46785 10 109 2.36E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS01385 9416ae031a753949153580195a831e2a 473 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 66 95 7.8E-90 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CDW54_RS01385 9416ae031a753949153580195a831e2a 473 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 168 196 7.8E-90 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CDW54_RS01385 9416ae031a753949153580195a831e2a 473 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 251 278 7.8E-90 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CDW54_RS01385 9416ae031a753949153580195a831e2a 473 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 4 27 7.8E-90 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CDW54_RS01385 9416ae031a753949153580195a831e2a 473 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 119 144 7.8E-90 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CDW54_RS01385 9416ae031a753949153580195a831e2a 473 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 359 381 7.8E-90 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CDW54_RS01385 9416ae031a753949153580195a831e2a 473 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 5 470 1.9E-223 T 28-03-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CDW54_RS01385 9416ae031a753949153580195a831e2a 473 PIRSF PIRSF000109 1 473 9.8E-240 T 28-03-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CDW54_RS01385 9416ae031a753949153580195a831e2a 473 SUPERFAMILY SSF48179 177 472 4.42E-135 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CDW54_RS01385 9416ae031a753949153580195a831e2a 473 Gene3D G3DSA:1.20.5.320 438 471 2.1E-18 T 28-03-2018 CDW54_RS01385 9416ae031a753949153580195a831e2a 473 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 174 2.6E-51 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CDW54_RS01385 9416ae031a753949153580195a831e2a 473 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 255 267 - T 28-03-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CDW54_RS01385 9416ae031a753949153580195a831e2a 473 SMART SM01350 179 470 4.8E-229 T 28-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CDW54_RS01385 9416ae031a753949153580195a831e2a 473 Gene3D G3DSA:1.10.1040.10 181 437 8.2E-115 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CDW54_RS01385 9416ae031a753949153580195a831e2a 473 Gene3D G3DSA:3.40.50.720 1 180 6.3E-37 T 28-03-2018 CDW54_RS01385 9416ae031a753949153580195a831e2a 473 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 179 469 2.8E-136 T 28-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CDW54_RS01385 9416ae031a753949153580195a831e2a 473 SUPERFAMILY SSF51735 4 173 7.49E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS02270 6ad2795eb05d7bedf2c1f2cd910acbe3 77 SUPERFAMILY SSF47336 2 70 2.75E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDW54_RS02270 6ad2795eb05d7bedf2c1f2cd910acbe3 77 Pfam PF00550 Phosphopantetheine attachment site 3 70 1.3E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDW54_RS02270 6ad2795eb05d7bedf2c1f2cd910acbe3 77 Gene3D G3DSA:1.10.1200.10 1 76 6.3E-12 T 28-03-2018 CDW54_RS02270 6ad2795eb05d7bedf2c1f2cd910acbe3 77 TIGRFAM TIGR01688 dltC: D-alanine--poly(phosphoribitol) ligase, subunit 2 3 71 2.0E-28 T 28-03-2018 IPR003230 D-alanine--poly(phosphoribitol) ligase subunit 2 GO:0019350|GO:0036370 KEGG: 00473+6.1.1.13 CDW54_RS02270 6ad2795eb05d7bedf2c1f2cd910acbe3 77 Hamap MF_00565 D-alanine--poly(phosphoribitol) ligase subunit 2 [dltC]. 1 76 45.143 T 28-03-2018 IPR003230 D-alanine--poly(phosphoribitol) ligase subunit 2 GO:0019350|GO:0036370 KEGG: 00473+6.1.1.13 CDW54_RS07840 0db73b13d3bf173d117ae9d90c2b1421 118 Gene3D G3DSA:3.40.30.10 2 116 7.1E-20 T 28-03-2018 CDW54_RS07840 0db73b13d3bf173d117ae9d90c2b1421 118 Pfam PF03960 ArsC family 40 110 5.4E-7 T 28-03-2018 IPR006660 Arsenate reductase-like CDW54_RS07840 0db73b13d3bf173d117ae9d90c2b1421 118 SUPERFAMILY SSF52833 3 115 1.21E-23 T 28-03-2018 IPR012336 Thioredoxin-like fold CDW54_RS06035 270cb6ccb2f4ba9a123b86b08d79df26 38 Pfam PF00444 Ribosomal protein L36 1 38 5.0E-23 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS06035 270cb6ccb2f4ba9a123b86b08d79df26 38 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 37 - T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS06035 270cb6ccb2f4ba9a123b86b08d79df26 38 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 10 38 6.0E-10 T 28-03-2018 CDW54_RS06035 270cb6ccb2f4ba9a123b86b08d79df26 38 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 38 18.92 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS06035 270cb6ccb2f4ba9a123b86b08d79df26 38 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 38 3.9E-23 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS06035 270cb6ccb2f4ba9a123b86b08d79df26 38 SUPERFAMILY SSF57840 1 38 8.24E-18 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS05185 d815ef4cbc9e732cde07516236d9132a 345 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 38 98 4.8E-8 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CDW54_RS05185 d815ef4cbc9e732cde07516236d9132a 345 Pfam PF13602 Zinc-binding dehydrogenase 199 339 1.2E-12 T 28-03-2018 CDW54_RS05185 d815ef4cbc9e732cde07516236d9132a 345 Gene3D G3DSA:3.40.50.720 159 275 2.8E-10 T 28-03-2018 CDW54_RS05185 d815ef4cbc9e732cde07516236d9132a 345 SUPERFAMILY SSF51735 122 285 2.37E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS05185 d815ef4cbc9e732cde07516236d9132a 345 Gene3D G3DSA:3.90.180.10 276 341 0.058 T 28-03-2018 CDW54_RS05185 d815ef4cbc9e732cde07516236d9132a 345 TIGRFAM TIGR02817 adh_fam_1: zinc-binding alcohol dehydrogenase family protein 8 341 1.4E-93 T 28-03-2018 IPR014182 Alcohol dehydrogenase, zinc-binding type 1 GO:0008270 CDW54_RS05185 d815ef4cbc9e732cde07516236d9132a 345 SMART SM00829 15 339 8.5E-10 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CDW54_RS05185 d815ef4cbc9e732cde07516236d9132a 345 SUPERFAMILY SSF50129 21 149 5.45E-31 T 28-03-2018 IPR011032 GroES-like CDW54_RS05185 d815ef4cbc9e732cde07516236d9132a 345 Gene3D G3DSA:3.90.180.10 14 158 2.2E-36 T 28-03-2018 CDW54_RS03805 6fcc582cde224f2f1f2af28657c8c6c8 233 SUPERFAMILY SSF100950 1 233 1.26E-82 T 28-03-2018 CDW54_RS03805 6fcc582cde224f2f1f2af28657c8c6c8 233 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 22 222 6.7E-15 T 28-03-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 CDW54_RS03805 6fcc582cde224f2f1f2af28657c8c6c8 233 Hamap MF_01241 Glucosamine-6-phosphate deaminase [nagB]. 1 233 41.563 T 28-03-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 CDW54_RS03805 6fcc582cde224f2f1f2af28657c8c6c8 233 Gene3D G3DSA:3.40.50.1360 1 233 1.6E-64 T 28-03-2018 CDW54_RS03805 6fcc582cde224f2f1f2af28657c8c6c8 233 ProSitePatterns PS01161 Glucosamine/galactosamine-6-phosphate isomerases signature. 112 130 - T 28-03-2018 IPR018321 Glucosamine-6-phosphate isomerase, conserved site GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 CDW54_RS03805 6fcc582cde224f2f1f2af28657c8c6c8 233 TIGRFAM TIGR00502 nagB: glucosamine-6-phosphate deaminase 1 233 2.0E-74 T 28-03-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 CDW54_RS02845 cc3ef5e848218d2c36b2c7a24532624b 221 SUPERFAMILY SSF56784 1 208 1.79E-44 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS02845 cc3ef5e848218d2c36b2c7a24532624b 221 TIGRFAM TIGR01990 bPGM: beta-phosphoglucomutase 2 190 1.1E-81 T 28-03-2018 IPR010972 Beta-phosphoglucomutase GO:0000287|GO:0005975|GO:0008801 KEGG: 00500+5.4.2.6|MetaCyc: PWY-2721|MetaCyc: PWY-2722|MetaCyc: PWY-7459 CDW54_RS02845 cc3ef5e848218d2c36b2c7a24532624b 221 Gene3D G3DSA:1.10.150.240 15 79 5.2E-23 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CDW54_RS02845 cc3ef5e848218d2c36b2c7a24532624b 221 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 83 189 6.2E-16 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDW54_RS02845 cc3ef5e848218d2c36b2c7a24532624b 221 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 4.7E-5 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDW54_RS02845 cc3ef5e848218d2c36b2c7a24532624b 221 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 133 149 4.7E-5 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDW54_RS02845 cc3ef5e848218d2c36b2c7a24532624b 221 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 151 171 4.7E-5 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDW54_RS02845 cc3ef5e848218d2c36b2c7a24532624b 221 Gene3D G3DSA:3.40.50.1000 80 216 5.5E-21 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS02845 cc3ef5e848218d2c36b2c7a24532624b 221 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 189 1.1E-21 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS02845 cc3ef5e848218d2c36b2c7a24532624b 221 TIGRFAM TIGR02009 PGMB-YQAB-SF: beta-phosphoglucomutase family hydrolase 2 189 2.3E-61 T 28-03-2018 IPR010976 Beta-phosphoglucomutase hydrolase CDW54_RS04520 e400c20d4cdfda4ff3e645e921ab981f 249 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 216 248 6.2E-5 T 28-03-2018 CDW54_RS04520 e400c20d4cdfda4ff3e645e921ab981f 249 Gene3D G3DSA:2.60.40.810 101 224 1.6E-30 T 28-03-2018 CDW54_RS04520 e400c20d4cdfda4ff3e645e921ab981f 249 Gene3D G3DSA:2.60.40.810 1 100 1.2E-30 T 28-03-2018 CDW54_RS04520 e400c20d4cdfda4ff3e645e921ab981f 249 SUPERFAMILY SSF49478 112 181 4.71E-10 T 28-03-2018 CDW54_RS04520 e400c20d4cdfda4ff3e645e921ab981f 249 SUPERFAMILY SSF49478 19 87 1.06E-9 T 28-03-2018 CDW54_RS04800 03f631ff1ade316b8aa99848e6fdcc69 156 SUPERFAMILY SSF50249 4 85 1.93E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDW54_RS04800 03f631ff1ade316b8aa99848e6fdcc69 156 Gene3D G3DSA:2.40.50.140 7 121 1.7E-28 T 28-03-2018 CDW54_RS04800 03f631ff1ade316b8aa99848e6fdcc69 156 SMART SM00316 4 74 1.6E-25 T 28-03-2018 IPR022967 RNA-binding domain, S1 CDW54_RS04800 03f631ff1ade316b8aa99848e6fdcc69 156 Pfam PF00575 S1 RNA binding domain 4 74 1.2E-20 T 28-03-2018 IPR003029 S1 domain GO:0003676 CDW54_RS07895 3b8dde436a89e52796363d7342ca5146 187 TIGRFAM TIGR00038 efp: translation elongation factor P 2 185 1.8E-69 T 28-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 CDW54_RS07895 3b8dde436a89e52796363d7342ca5146 187 Gene3D G3DSA:2.40.50.140 64 127 4.4E-21 T 28-03-2018 CDW54_RS07895 3b8dde436a89e52796363d7342ca5146 187 Pfam PF09285 Elongation factor P, C-terminal 129 184 1.0E-21 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 CDW54_RS07895 3b8dde436a89e52796363d7342ca5146 187 PIRSF PIRSF005901 1 186 1.0E-65 T 28-03-2018 IPR020599 Translation elongation factor P/YeiP CDW54_RS07895 3b8dde436a89e52796363d7342ca5146 187 Gene3D G3DSA:2.40.50.140 129 184 1.8E-22 T 28-03-2018 CDW54_RS07895 3b8dde436a89e52796363d7342ca5146 187 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 8.3E-24 T 28-03-2018 IPR013185 Translation elongation factor, KOW-like CDW54_RS07895 3b8dde436a89e52796363d7342ca5146 187 Hamap MF_00141 Elongation factor P [efp]. 1 185 46.977 T 28-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 CDW54_RS07895 3b8dde436a89e52796363d7342ca5146 187 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 121 3.3E-18 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 CDW54_RS07895 3b8dde436a89e52796363d7342ca5146 187 SUPERFAMILY SSF50104 1 63 1.02E-19 T 28-03-2018 IPR008991 Translation protein SH3-like domain CDW54_RS07895 3b8dde436a89e52796363d7342ca5146 187 SUPERFAMILY SSF50249 65 129 1.24E-19 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDW54_RS07895 3b8dde436a89e52796363d7342ca5146 187 ProSitePatterns PS01275 Elongation factor P signature. 150 169 - T 28-03-2018 IPR013852 Translation elongation factor P/YeiP, conserved site CDW54_RS07895 3b8dde436a89e52796363d7342ca5146 187 Gene3D G3DSA:2.30.30.30 2 61 2.0E-23 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 CDW54_RS07895 3b8dde436a89e52796363d7342ca5146 187 SMART SM00841 129 184 4.7E-28 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 CDW54_RS07895 3b8dde436a89e52796363d7342ca5146 187 SUPERFAMILY SSF50249 128 185 3.94E-16 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDW54_RS07895 3b8dde436a89e52796363d7342ca5146 187 SMART SM01185 67 121 3.4E-21 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 CDW54_RS00090 52e7995c793286ead4d0c79860b41202 123 Pfam PF06486 Protein of unknown function (DUF1093) 42 111 6.2E-15 T 28-03-2018 IPR006542 Protein of unknown function DUF1093 CDW54_RS00090 52e7995c793286ead4d0c79860b41202 123 SUPERFAMILY SSF159121 40 121 2.09E-18 T 28-03-2018 IPR006542 Protein of unknown function DUF1093 CDW54_RS00090 52e7995c793286ead4d0c79860b41202 123 TIGRFAM TIGR01655 yxeA_fam: conserved hypothetical protein 6 119 3.5E-11 T 28-03-2018 IPR006542 Protein of unknown function DUF1093 CDW54_RS11140 1357ac6ce50bd57387c597202af42cff 416 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 3 410 52.196 T 28-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 CDW54_RS11140 1357ac6ce50bd57387c597202af42cff 416 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 312 390 7.0E-18 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CDW54_RS11140 1357ac6ce50bd57387c597202af42cff 416 Gene3D G3DSA:3.40.50.300 54 310 3.2E-70 T 28-03-2018 CDW54_RS11140 1357ac6ce50bd57387c597202af42cff 416 Gene3D G3DSA:1.10.8.60 312 401 6.0E-34 T 28-03-2018 CDW54_RS11140 1357ac6ce50bd57387c597202af42cff 416 SUPERFAMILY SSF52540 59 397 2.89E-76 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS11140 1357ac6ce50bd57387c597202af42cff 416 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 8 404 2.6E-201 T 28-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 CDW54_RS11140 1357ac6ce50bd57387c597202af42cff 416 SMART SM00382 110 267 9.3E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS11140 1357ac6ce50bd57387c597202af42cff 416 SMART SM00994 10 49 9.4E-22 T 28-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CDW54_RS11140 1357ac6ce50bd57387c597202af42cff 416 SUPERFAMILY SSF57716 11 46 7.98E-11 T 28-03-2018 CDW54_RS11140 1357ac6ce50bd57387c597202af42cff 416 SMART SM01086 312 406 6.5E-35 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CDW54_RS11140 1357ac6ce50bd57387c597202af42cff 416 Pfam PF07724 AAA domain (Cdc48 subfamily) 110 305 1.5E-49 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CDW54_RS11140 1357ac6ce50bd57387c597202af42cff 416 Pfam PF06689 ClpX C4-type zinc finger 12 48 6.8E-19 T 28-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CDW54_RS02140 beceaae3298203fbbe6c8563a22baeba 284 SUPERFAMILY SSF53223 1 120 1.82E-41 T 28-03-2018 CDW54_RS02140 beceaae3298203fbbe6c8563a22baeba 284 Hamap MF_01576 Bifunctional protein FolD [folD]. 2 281 38.703 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CDW54_RS02140 beceaae3298203fbbe6c8563a22baeba 284 Gene3D G3DSA:3.40.50.720 138 262 1.2E-41 T 28-03-2018 CDW54_RS02140 beceaae3298203fbbe6c8563a22baeba 284 SUPERFAMILY SSF51735 121 278 6.86E-53 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS02140 beceaae3298203fbbe6c8563a22baeba 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 32 54 1.4E-82 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CDW54_RS02140 beceaae3298203fbbe6c8563a22baeba 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 237 253 1.4E-82 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CDW54_RS02140 beceaae3298203fbbe6c8563a22baeba 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 202 231 1.4E-82 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CDW54_RS02140 beceaae3298203fbbe6c8563a22baeba 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 108 129 1.4E-82 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CDW54_RS02140 beceaae3298203fbbe6c8563a22baeba 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 153 173 1.4E-82 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CDW54_RS02140 beceaae3298203fbbe6c8563a22baeba 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 254 272 1.4E-82 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CDW54_RS02140 beceaae3298203fbbe6c8563a22baeba 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 73 100 1.4E-82 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CDW54_RS02140 beceaae3298203fbbe6c8563a22baeba 284 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 258 266 - T 28-03-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CDW54_RS02140 beceaae3298203fbbe6c8563a22baeba 284 Gene3D G3DSA:3.40.50.10860 10 137 1.5E-48 T 28-03-2018 CDW54_RS02140 beceaae3298203fbbe6c8563a22baeba 284 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 122 278 2.3E-69 T 28-03-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CDW54_RS02140 beceaae3298203fbbe6c8563a22baeba 284 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 4 119 8.7E-42 T 28-03-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CDW54_RS02140 beceaae3298203fbbe6c8563a22baeba 284 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 74 99 - T 28-03-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CDW54_RS10685 df7dedb9a8ec1412839e68f764423e6e 268 Pfam PF00005 ABC transporter 20 167 9.6E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS10685 df7dedb9a8ec1412839e68f764423e6e 268 Gene3D G3DSA:3.40.50.300 2 240 1.5E-59 T 28-03-2018 CDW54_RS10685 df7dedb9a8ec1412839e68f764423e6e 268 SMART SM00382 28 217 1.4E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS10685 df7dedb9a8ec1412839e68f764423e6e 268 SUPERFAMILY SSF52540 4 230 7.48E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS05340 d4888ce875ccb416f28ee7babedc4ecf 341 Gene3D G3DSA:3.40.50.2300 173 339 5.6E-35 T 28-03-2018 CDW54_RS05340 d4888ce875ccb416f28ee7babedc4ecf 341 SMART SM00354 2 72 1.0E-27 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS05340 d4888ce875ccb416f28ee7babedc4ecf 341 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 5.6E-19 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS05340 d4888ce875ccb416f28ee7babedc4ecf 341 Pfam PF13377 Periplasmic binding protein-like domain 175 335 5.6E-26 T 28-03-2018 CDW54_RS05340 d4888ce875ccb416f28ee7babedc4ecf 341 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 28-03-2018 CDW54_RS05340 d4888ce875ccb416f28ee7babedc4ecf 341 SUPERFAMILY SSF53822 74 337 1.86E-67 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CDW54_RS05340 d4888ce875ccb416f28ee7babedc4ecf 341 Gene3D G3DSA:3.40.50.2300 59 172 8.0E-17 T 28-03-2018 CDW54_RS05340 d4888ce875ccb416f28ee7babedc4ecf 341 SUPERFAMILY SSF47413 2 57 3.48E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDW54_RS05340 d4888ce875ccb416f28ee7babedc4ecf 341 Gene3D G3DSA:1.10.260.40 19 58 2.0E-19 T 28-03-2018 CDW54_RS05340 d4888ce875ccb416f28ee7babedc4ecf 341 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 1.5E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS05340 d4888ce875ccb416f28ee7babedc4ecf 341 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 1.5E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS05340 d4888ce875ccb416f28ee7babedc4ecf 341 Gene3D G3DSA:1.10.10.10 2 18 0.0021 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS01755 4ad77ff6d71b32668dfac5ba3f67a1af 355 Pfam PF07730 Histidine kinase 155 223 2.0E-18 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CDW54_RS01755 4ad77ff6d71b32668dfac5ba3f67a1af 355 SUPERFAMILY SSF55874 232 351 1.44E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS01755 4ad77ff6d71b32668dfac5ba3f67a1af 355 PIRSF PIRSF037431 6 355 3.6E-137 T 28-03-2018 IPR017202 Sensor histidine kinase LiaS/VraS GO:0000155|GO:0000160|GO:0004673|GO:0016021 CDW54_RS01755 4ad77ff6d71b32668dfac5ba3f67a1af 355 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 262 351 3.2E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS01755 4ad77ff6d71b32668dfac5ba3f67a1af 355 SMART SM00387 260 353 9.3E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS01755 4ad77ff6d71b32668dfac5ba3f67a1af 355 Gene3D G3DSA:3.30.565.10 221 355 6.4E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS05065 64ec0151fb4a30c183c34884657ca52b 192 Pfam PF04542 Sigma-70 region 2 20 88 2.8E-11 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDW54_RS05065 64ec0151fb4a30c183c34884657ca52b 192 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 15 186 5.6E-15 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDW54_RS05065 64ec0151fb4a30c183c34884657ca52b 192 Gene3D G3DSA:1.10.1740.10 1 104 7.7E-19 T 28-03-2018 CDW54_RS05065 64ec0151fb4a30c183c34884657ca52b 192 SUPERFAMILY SSF88946 3 102 2.51E-20 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDW54_RS12320 aae5ce42e4c750e4f25af086db253330 568 Gene3D G3DSA:3.40.970.40 238 287 4.6E-10 T 28-03-2018 CDW54_RS12320 aae5ce42e4c750e4f25af086db253330 568 Pfam PF05670 Domain of unknown function (DUF814) 451 535 8.0E-27 T 28-03-2018 IPR008532 Domain of unknown function DUF814 CDW54_RS12320 aae5ce42e4c750e4f25af086db253330 568 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 4 443 3.0E-153 T 28-03-2018 CDW54_RS12320 aae5ce42e4c750e4f25af086db253330 568 Gene3D G3DSA:1.20.5.340 288 442 2.4E-4 T 28-03-2018 CDW54_RS12320 aae5ce42e4c750e4f25af086db253330 568 Gene3D G3DSA:1.10.8.50 168 235 6.0E-6 T 28-03-2018 CDW54_RS12320 aae5ce42e4c750e4f25af086db253330 568 Gene3D G3DSA:2.30.310.10 1 167 1.0E-50 T 28-03-2018 CDW54_RS05270 80bdd8a3eaebf95ceca5b9050aec722e 512 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 363 383 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CDW54_RS05270 80bdd8a3eaebf95ceca5b9050aec722e 512 SUPERFAMILY SSF53067 248 495 2.28E-56 T 28-03-2018 CDW54_RS05270 80bdd8a3eaebf95ceca5b9050aec722e 512 Gene3D G3DSA:3.30.420.40 244 509 4.4E-56 T 28-03-2018 CDW54_RS05270 80bdd8a3eaebf95ceca5b9050aec722e 512 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 246 1.7E-63 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CDW54_RS05270 80bdd8a3eaebf95ceca5b9050aec722e 512 SUPERFAMILY SSF53067 5 249 9.39E-64 T 28-03-2018 CDW54_RS05270 80bdd8a3eaebf95ceca5b9050aec722e 512 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 255 446 4.6E-34 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CDW54_RS05270 80bdd8a3eaebf95ceca5b9050aec722e 512 PIRSF PIRSF000538 1 502 1.5E-133 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CDW54_RS05270 80bdd8a3eaebf95ceca5b9050aec722e 512 Gene3D G3DSA:3.30.420.40 1 243 9.1E-65 T 28-03-2018 CDW54_RS02415 c2b940dd7ba0de6547f4cc624023d5e2 472 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 5 93 4.2E-15 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CDW54_RS02415 c2b940dd7ba0de6547f4cc624023d5e2 472 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 107 449 2.3E-113 T 28-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 CDW54_RS02415 c2b940dd7ba0de6547f4cc624023d5e2 472 Pfam PF02378 Phosphotransferase system, EIIC 125 393 7.2E-16 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CDW54_RS02415 c2b940dd7ba0de6547f4cc624023d5e2 472 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 4 86 3.0E-28 T 28-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 CDW54_RS02415 c2b940dd7ba0de6547f4cc624023d5e2 472 SUPERFAMILY SSF52794 2 98 7.32E-30 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CDW54_RS02415 c2b940dd7ba0de6547f4cc624023d5e2 472 Gene3D G3DSA:3.40.50.2300 2 97 4.9E-33 T 28-03-2018 CDW54_RS09055 540a49920396f51102c6c486a23c59f3 326 SUPERFAMILY SSF53659 10 322 1.36E-89 T 28-03-2018 CDW54_RS09055 540a49920396f51102c6c486a23c59f3 326 Pfam PF01515 Phosphate acetyl/butaryl transferase 14 320 9.2E-117 T 28-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CDW54_RS09055 540a49920396f51102c6c486a23c59f3 326 PIRSF PIRSF000428 2 325 4.2E-105 T 28-03-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CDW54_RS09055 540a49920396f51102c6c486a23c59f3 326 Gene3D G3DSA:3.40.50.10750 141 296 6.8E-63 T 28-03-2018 CDW54_RS09055 540a49920396f51102c6c486a23c59f3 326 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 18 320 8.5E-115 T 28-03-2018 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CDW54_RS07575 5b466f6e5722db06b2d43730180e0c84 386 Gene3D G3DSA:2.40.260.10 39 249 1.2E-41 T 28-03-2018 IPR023365 Sortase domain CDW54_RS07575 5b466f6e5722db06b2d43730180e0c84 386 Pfam PF04203 Sortase family 106 230 2.7E-21 T 28-03-2018 IPR005754 Sortase family CDW54_RS07575 5b466f6e5722db06b2d43730180e0c84 386 SUPERFAMILY SSF63817 101 234 5.23E-39 T 28-03-2018 IPR023365 Sortase domain CDW54_RS07575 5b466f6e5722db06b2d43730180e0c84 386 TIGRFAM TIGR01076 sortase_fam: sortase 104 236 7.0E-43 T 28-03-2018 IPR005754 Sortase family CDW54_RS07575 5b466f6e5722db06b2d43730180e0c84 386 Gene3D G3DSA:2.60.40.10 281 364 1.6E-5 T 28-03-2018 IPR013783 Immunoglobulin-like fold CDW54_RS08805 450dba3321be33872f20597ce61e5628 191 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 3 177 2.2E-39 T 28-03-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG CDW54_RS08805 450dba3321be33872f20597ce61e5628 191 Pfam PF03641 Possible lysine decarboxylase 45 175 1.6E-30 T 28-03-2018 IPR031100 LOG family CDW54_RS08805 450dba3321be33872f20597ce61e5628 191 Gene3D G3DSA:3.40.50.450 2 184 1.1E-40 T 28-03-2018 CDW54_RS08805 450dba3321be33872f20597ce61e5628 191 SUPERFAMILY SSF102405 2 177 8.85E-49 T 28-03-2018 CDW54_RS12480 e980285e6f2811c94979a4a7f61fd7cc 449 PIRSF PIRSF006060 5 448 3.7E-79 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CDW54_RS12480 e980285e6f2811c94979a4a7f61fd7cc 449 Pfam PF13520 Amino acid permease 23 421 5.5E-54 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CDW54_RS02515 5c9a8732935bbdfefbbfa80201da66d1 161 Gene3D G3DSA:2.160.10.10 2 158 9.3E-40 T 28-03-2018 CDW54_RS02515 5c9a8732935bbdfefbbfa80201da66d1 161 SUPERFAMILY SSF51161 4 155 3.33E-45 T 28-03-2018 IPR011004 Trimeric LpxA-like CDW54_RS02515 5c9a8732935bbdfefbbfa80201da66d1 161 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 74 108 1.6E-8 T 28-03-2018 IPR001451 Hexapeptide repeat CDW54_RS11870 6e14d53316c288c30b772e2508e751fc 587 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 202 246 2.1E-5 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CDW54_RS11870 6e14d53316c288c30b772e2508e751fc 587 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 8 199 2.3E-76 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CDW54_RS11870 6e14d53316c288c30b772e2508e751fc 587 Pfam PF02780 Transketolase, C-terminal domain 461 576 2.4E-14 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CDW54_RS11870 6e14d53316c288c30b772e2508e751fc 587 Gene3D G3DSA:3.40.50.920 458 586 4.6E-23 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CDW54_RS11870 6e14d53316c288c30b772e2508e751fc 587 SUPERFAMILY SSF52922 458 585 5.23E-20 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CDW54_RS11870 6e14d53316c288c30b772e2508e751fc 587 SUPERFAMILY SSF52518 4 345 1.84E-64 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CDW54_RS11870 6e14d53316c288c30b772e2508e751fc 587 SUPERFAMILY SSF52518 301 444 2.94E-34 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CDW54_RS11870 6e14d53316c288c30b772e2508e751fc 587 Gene3D G3DSA:3.40.50.970 292 452 2.5E-33 T 28-03-2018 CDW54_RS11870 6e14d53316c288c30b772e2508e751fc 587 Pfam PF02779 Transketolase, pyrimidine binding domain 312 442 2.6E-21 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CDW54_RS11870 6e14d53316c288c30b772e2508e751fc 587 ProSitePatterns PS00801 Transketolase signature 1. 33 52 - T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CDW54_RS11870 6e14d53316c288c30b772e2508e751fc 587 Gene3D G3DSA:3.40.50.970 1 277 3.5E-67 T 28-03-2018 CDW54_RS11870 6e14d53316c288c30b772e2508e751fc 587 SMART SM00861 282 446 3.3E-31 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CDW54_RS10165 9e4137a04de1e1cb2cec1644c19a7354 399 Gene3D G3DSA:3.40.50.620 210 356 8.5E-30 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDW54_RS10165 9e4137a04de1e1cb2cec1644c19a7354 399 Pfam PF02698 DUF218 domain 219 369 1.0E-31 T 28-03-2018 IPR003848 Domain of unknown function DUF218 CDW54_RS07940 bfbfcaac51cbc2fdee5e366cc455d24f 389 SUPERFAMILY SSF53383 7 387 7.58E-110 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDW54_RS07940 bfbfcaac51cbc2fdee5e366cc455d24f 389 Gene3D G3DSA:3.40.640.10 46 298 2.7E-58 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDW54_RS07940 bfbfcaac51cbc2fdee5e366cc455d24f 389 Pfam PF00155 Aminotransferase class I and II 32 382 7.3E-71 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CDW54_RS07940 bfbfcaac51cbc2fdee5e366cc455d24f 389 Gene3D G3DSA:3.90.1150.10 299 389 1.5E-25 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDW54_RS07940 bfbfcaac51cbc2fdee5e366cc455d24f 389 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 234 247 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CDW54_RS03190 fd1d9b5e51a666fd984d68a384c4ef3e 273 SUPERFAMILY SSF46785 205 268 5.71E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS03190 fd1d9b5e51a666fd984d68a384c4ef3e 273 Gene3D G3DSA:1.10.10.10 203 269 1.2E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS03190 fd1d9b5e51a666fd984d68a384c4ef3e 273 Pfam PF00293 NUDIX domain 47 154 4.6E-17 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CDW54_RS03190 fd1d9b5e51a666fd984d68a384c4ef3e 273 Gene3D G3DSA:1.10.287.1030 3 34 9.0E-16 T 28-03-2018 CDW54_RS03190 fd1d9b5e51a666fd984d68a384c4ef3e 273 SUPERFAMILY SSF55811 3 202 4.46E-35 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CDW54_RS03190 fd1d9b5e51a666fd984d68a384c4ef3e 273 Gene3D G3DSA:3.90.79.10 35 202 1.1E-39 T 28-03-2018 CDW54_RS10570 c6f81195aeafda27c73255b661e4c691 252 Gene3D G3DSA:3.20.20.70 1 251 4.1E-76 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDW54_RS10570 c6f81195aeafda27c73255b661e4c691 252 TIGRFAM TIGR01093 aroD: 3-dehydroquinate dehydratase, type I 15 244 3.6E-62 T 28-03-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CDW54_RS10570 c6f81195aeafda27c73255b661e4c691 252 Hamap MF_00214 3-dehydroquinate dehydratase [aroD]. 15 248 35.523 T 28-03-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CDW54_RS10570 c6f81195aeafda27c73255b661e4c691 252 SUPERFAMILY SSF51569 2 249 4.76E-73 T 28-03-2018 CDW54_RS10570 c6f81195aeafda27c73255b661e4c691 252 Pfam PF01487 Type I 3-dehydroquinase 17 244 4.4E-66 T 28-03-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CDW54_RS00875 e94cbb2e596fde36373bf61291fae8eb 402 Pfam PF13735 tRNA nucleotidyltransferase domain 2 putative 250 395 3.9E-48 T 28-03-2018 IPR032810 CCA-adding enzyme, C-terminal CDW54_RS00875 e94cbb2e596fde36373bf61291fae8eb 402 Hamap MF_01263 CCA-adding enzyme [cca]. 7 400 41.26 T 28-03-2018 IPR023068 CCA-adding enzyme, firmicutes GO:0001680|GO:0004810|GO:0016437 CDW54_RS00875 e94cbb2e596fde36373bf61291fae8eb 402 SUPERFAMILY SSF81301 10 143 1.2E-43 T 28-03-2018 CDW54_RS00875 e94cbb2e596fde36373bf61291fae8eb 402 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 174 223 3.9E-12 T 28-03-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CDW54_RS00875 e94cbb2e596fde36373bf61291fae8eb 402 Gene3D G3DSA:3.30.460.10 8 146 8.5E-48 T 28-03-2018 CDW54_RS00875 e94cbb2e596fde36373bf61291fae8eb 402 SUPERFAMILY SSF81891 145 397 9.16E-52 T 28-03-2018 CDW54_RS00875 e94cbb2e596fde36373bf61291fae8eb 402 Gene3D G3DSA:1.10.3090.10 147 391 3.8E-38 T 28-03-2018 CDW54_RS00875 e94cbb2e596fde36373bf61291fae8eb 402 Pfam PF01743 Poly A polymerase head domain 27 147 1.9E-38 T 28-03-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CDW54_RS06010 234be115aa9ca151aaf7b08860d9c7f3 59 Pfam PF00327 Ribosomal protein L30p/L7e 4 54 9.0E-21 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CDW54_RS06010 234be115aa9ca151aaf7b08860d9c7f3 59 Gene3D G3DSA:3.30.1390.20 4 58 1.9E-24 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CDW54_RS06010 234be115aa9ca151aaf7b08860d9c7f3 59 SUPERFAMILY SSF55129 1 59 7.33E-20 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CDW54_RS06010 234be115aa9ca151aaf7b08860d9c7f3 59 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 18.453 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS06010 234be115aa9ca151aaf7b08860d9c7f3 59 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 58 1.0E-26 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS06010 234be115aa9ca151aaf7b08860d9c7f3 59 PIRSF PIRSF002211 1 59 8.3E-28 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS06010 234be115aa9ca151aaf7b08860d9c7f3 59 ProSitePatterns PS00634 Ribosomal protein L30 signature. 22 54 - T 28-03-2018 IPR018038 Ribosomal protein L30, conserved site CDW54_RS07765 2d8c1da1ed004944d0023837458f6792 903 Pfam PF02687 FtsX-like permease family 803 893 4.6E-6 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CDW54_RS07765 2d8c1da1ed004944d0023837458f6792 903 Pfam PF02687 FtsX-like permease family 401 491 1.5E-7 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CDW54_RS07765 2d8c1da1ed004944d0023837458f6792 903 Gene3D G3DSA:1.20.1600.10 168 453 5.4E-6 T 28-03-2018 CDW54_RS07765 2d8c1da1ed004944d0023837458f6792 903 Gene3D G3DSA:1.20.1250.20 517 892 0.015 T 28-03-2018 CDW54_RS07765 2d8c1da1ed004944d0023837458f6792 903 Pfam PF12704 MacB-like periplasmic core domain 24 203 1.9E-6 T 28-03-2018 IPR025857 MacB-like periplasmic core domain CDW54_RS02775 d87aef2efb6297dd8ca3911650de9235 348 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 47 3.3E-18 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS02775 d87aef2efb6297dd8ca3911650de9235 348 SUPERFAMILY SSF53822 82 345 6.56E-64 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CDW54_RS02775 d87aef2efb6297dd8ca3911650de9235 348 Gene3D G3DSA:3.40.50.2300 183 346 2.0E-49 T 28-03-2018 CDW54_RS02775 d87aef2efb6297dd8ca3911650de9235 348 SUPERFAMILY SSF47413 2 58 7.5E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDW54_RS02775 d87aef2efb6297dd8ca3911650de9235 348 SMART SM00354 1 71 5.2E-26 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS02775 d87aef2efb6297dd8ca3911650de9235 348 Gene3D G3DSA:1.10.260.40 2 57 7.2E-20 T 28-03-2018 CDW54_RS02775 d87aef2efb6297dd8ca3911650de9235 348 Gene3D G3DSA:3.40.50.2300 58 182 1.8E-15 T 28-03-2018 CDW54_RS02775 d87aef2efb6297dd8ca3911650de9235 348 Pfam PF13377 Periplasmic binding protein-like domain 185 344 7.6E-35 T 28-03-2018 CDW54_RS08240 1421fe2ad296c3d4094e7614af47dddc 473 TIGRFAM TIGR03810 arg_ornith_anti: arginine-ornithine antiporter 11 473 1.4E-183 T 28-03-2018 IPR022461 Arginine/ornithine antiporter GO:0005887|GO:0006527|GO:0043858 CDW54_RS08240 1421fe2ad296c3d4094e7614af47dddc 473 Pfam PF13520 Amino acid permease 8 422 1.9E-59 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CDW54_RS08240 1421fe2ad296c3d4094e7614af47dddc 473 TIGRFAM TIGR00905 2A0302: transporter, basic amino acid/polyamine antiporter (APA) family 2 473 1.0E-156 T 28-03-2018 IPR004754 Amino acid antiporter GO:0006865|GO:0016021 CDW54_RS08240 1421fe2ad296c3d4094e7614af47dddc 473 PIRSF PIRSF006060 1 473 5.0E-52 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CDW54_RS00285 ecbfc4c402047bdca329f82422fc04df 590 Pfam PF09382 RQC domain 396 505 9.0E-32 T 28-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 CDW54_RS00285 ecbfc4c402047bdca329f82422fc04df 590 Gene3D G3DSA:1.10.10.10 344 502 2.7E-45 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS00285 ecbfc4c402047bdca329f82422fc04df 590 Pfam PF00570 HRDC domain 516 578 8.9E-22 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CDW54_RS00285 ecbfc4c402047bdca329f82422fc04df 590 SUPERFAMILY SSF47819 512 582 7.41E-24 T 28-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 CDW54_RS00285 ecbfc4c402047bdca329f82422fc04df 590 Pfam PF16124 RecQ zinc-binding 331 393 3.2E-16 T 28-03-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain CDW54_RS00285 ecbfc4c402047bdca329f82422fc04df 590 Gene3D G3DSA:1.10.150.80 503 588 6.9E-26 T 28-03-2018 CDW54_RS00285 ecbfc4c402047bdca329f82422fc04df 590 Pfam PF00270 DEAD/DEAH box helicase 16 176 2.5E-21 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CDW54_RS00285 ecbfc4c402047bdca329f82422fc04df 590 Gene3D G3DSA:3.40.50.300 1 197 5.1E-34 T 28-03-2018 CDW54_RS00285 ecbfc4c402047bdca329f82422fc04df 590 SUPERFAMILY SSF46785 391 536 1.32E-35 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS00285 ecbfc4c402047bdca329f82422fc04df 590 SMART SM00956 400 503 1.0E-36 T 28-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 CDW54_RS00285 ecbfc4c402047bdca329f82422fc04df 590 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 2 582 2.1E-239 T 28-03-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 CDW54_RS00285 ecbfc4c402047bdca329f82422fc04df 590 SUPERFAMILY SSF52540 54 342 1.41E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS00285 ecbfc4c402047bdca329f82422fc04df 590 SMART SM00487 10 207 4.4E-30 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CDW54_RS00285 ecbfc4c402047bdca329f82422fc04df 590 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 4 452 3.8E-140 T 28-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 CDW54_RS00285 ecbfc4c402047bdca329f82422fc04df 590 SMART SM00490 239 320 1.8E-27 T 28-03-2018 IPR001650 Helicase, C-terminal CDW54_RS00285 ecbfc4c402047bdca329f82422fc04df 590 SMART SM00341 510 590 1.4E-17 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CDW54_RS00285 ecbfc4c402047bdca329f82422fc04df 590 Gene3D G3DSA:3.40.50.300 199 343 1.6E-33 T 28-03-2018 CDW54_RS00285 ecbfc4c402047bdca329f82422fc04df 590 Pfam PF00271 Helicase conserved C-terminal domain 212 319 1.5E-19 T 28-03-2018 IPR001650 Helicase, C-terminal CDW54_RS01965 64ed1873c23d693b9640ba89352cb5f1 486 Pfam PF02378 Phosphotransferase system, EIIC 29 410 2.3E-55 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CDW54_RS01965 64ed1873c23d693b9640ba89352cb5f1 486 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 12 479 2.0E-94 T 28-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 CDW54_RS01965 64ed1873c23d693b9640ba89352cb5f1 486 PIRSF PIRSF006351 1 486 2.5E-126 T 28-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 CDW54_RS05990 fed4f674409a29c061b2c81672ddeaf9 132 Pfam PF00410 Ribosomal protein S8 5 132 1.3E-53 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS05990 fed4f674409a29c061b2c81672ddeaf9 132 Gene3D G3DSA:3.30.1490.10 76 131 2.2E-23 T 28-03-2018 CDW54_RS05990 fed4f674409a29c061b2c81672ddeaf9 132 SUPERFAMILY SSF56047 2 132 7.72E-49 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS05990 fed4f674409a29c061b2c81672ddeaf9 132 ProSitePatterns PS00053 Ribosomal protein S8 signature. 102 119 - T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS05990 fed4f674409a29c061b2c81672ddeaf9 132 Gene3D G3DSA:3.30.1370.30 1 66 1.2E-26 T 28-03-2018 CDW54_RS05990 fed4f674409a29c061b2c81672ddeaf9 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 32.671 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS07965 a27dfdb3585ddaf22e86c9f2075aa329 460 Pfam PF11799 impB/mucB/samB family C-terminal domain 269 380 3.2E-17 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CDW54_RS07965 a27dfdb3585ddaf22e86c9f2075aa329 460 Pfam PF11798 IMS family HHH motif 197 229 1.1E-10 T 28-03-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CDW54_RS07965 a27dfdb3585ddaf22e86c9f2075aa329 460 Pfam PF00817 impB/mucB/samB family 22 181 1.0E-26 T 28-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CDW54_RS07965 a27dfdb3585ddaf22e86c9f2075aa329 460 Gene3D G3DSA:3.30.1490.100 278 392 3.8E-21 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CDW54_RS07965 a27dfdb3585ddaf22e86c9f2075aa329 460 Gene3D G3DSA:1.10.150.20 202 277 7.5E-18 T 28-03-2018 CDW54_RS07965 a27dfdb3585ddaf22e86c9f2075aa329 460 SUPERFAMILY SSF100879 274 378 1.53E-10 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CDW54_RS07965 a27dfdb3585ddaf22e86c9f2075aa329 460 Gene3D G3DSA:3.30.70.270 142 201 3.1E-7 T 28-03-2018 CDW54_RS07965 a27dfdb3585ddaf22e86c9f2075aa329 460 Gene3D G3DSA:3.30.70.270 63 141 1.6E-10 T 28-03-2018 CDW54_RS07965 a27dfdb3585ddaf22e86c9f2075aa329 460 SUPERFAMILY SSF56672 9 265 2.4E-55 T 28-03-2018 CDW54_RS07745 e1715b6e1f147363ea5a3bb822ad9e85 305 TIGRFAM TIGR02152 D_ribokin_bact: ribokinase 4 301 2.8E-111 T 28-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 CDW54_RS07745 e1715b6e1f147363ea5a3bb822ad9e85 305 Hamap MF_01987 Ribokinase [rbsK]. 2 303 25.39 T 28-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 CDW54_RS07745 e1715b6e1f147363ea5a3bb822ad9e85 305 PRINTS PR00990 Ribokinase signature 105 118 5.4E-32 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CDW54_RS07745 e1715b6e1f147363ea5a3bb822ad9e85 305 PRINTS PR00990 Ribokinase signature 6 27 5.4E-32 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CDW54_RS07745 e1715b6e1f147363ea5a3bb822ad9e85 305 PRINTS PR00990 Ribokinase signature 218 229 5.4E-32 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CDW54_RS07745 e1715b6e1f147363ea5a3bb822ad9e85 305 PRINTS PR00990 Ribokinase signature 174 189 5.4E-32 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CDW54_RS07745 e1715b6e1f147363ea5a3bb822ad9e85 305 PRINTS PR00990 Ribokinase signature 33 52 5.4E-32 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CDW54_RS07745 e1715b6e1f147363ea5a3bb822ad9e85 305 Gene3D G3DSA:3.40.1190.20 2 304 8.6E-75 T 28-03-2018 IPR029056 Ribokinase-like CDW54_RS07745 e1715b6e1f147363ea5a3bb822ad9e85 305 Pfam PF00294 pfkB family carbohydrate kinase 1 295 3.8E-67 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CDW54_RS07745 e1715b6e1f147363ea5a3bb822ad9e85 305 SUPERFAMILY SSF53613 1 302 7.17E-82 T 28-03-2018 IPR029056 Ribokinase-like CDW54_RS07745 e1715b6e1f147363ea5a3bb822ad9e85 305 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 247 260 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CDW54_RS00190 8114b1bd188b20ed44f0af69c34cf09b 642 Gene3D G3DSA:3.40.1110.10 334 438 5.9E-16 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CDW54_RS00190 8114b1bd188b20ed44f0af69c34cf09b 642 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 86 592 1.2E-75 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDW54_RS00190 8114b1bd188b20ed44f0af69c34cf09b 642 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 63 614 2.1E-172 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CDW54_RS00190 8114b1bd188b20ed44f0af69c34cf09b 642 SUPERFAMILY SSF81665 65 117 6.15E-14 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CDW54_RS00190 8114b1bd188b20ed44f0af69c34cf09b 642 SUPERFAMILY SSF81665 557 577 6.15E-14 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CDW54_RS00190 8114b1bd188b20ed44f0af69c34cf09b 642 SUPERFAMILY SSF81665 215 309 6.15E-14 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CDW54_RS00190 8114b1bd188b20ed44f0af69c34cf09b 642 Pfam PF00122 E1-E2 ATPase 114 295 1.7E-42 T 28-03-2018 CDW54_RS00190 8114b1bd188b20ed44f0af69c34cf09b 642 Gene3D G3DSA:3.40.50.1000 439 571 1.3E-35 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS00190 8114b1bd188b20ed44f0af69c34cf09b 642 ProSitePatterns PS01229 Hypothetical cof family signature 2. 512 534 - T 28-03-2018 CDW54_RS00190 8114b1bd188b20ed44f0af69c34cf09b 642 SUPERFAMILY SSF56784 314 333 5.21E-53 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS00190 8114b1bd188b20ed44f0af69c34cf09b 642 SUPERFAMILY SSF56784 409 611 5.21E-53 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS00190 8114b1bd188b20ed44f0af69c34cf09b 642 PRINTS PR00941 Cadmium-transporting ATPase signature 26 43 1.8E-11 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CDW54_RS00190 8114b1bd188b20ed44f0af69c34cf09b 642 PRINTS PR00941 Cadmium-transporting ATPase signature 199 213 1.8E-11 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CDW54_RS00190 8114b1bd188b20ed44f0af69c34cf09b 642 PRINTS PR00941 Cadmium-transporting ATPase signature 98 118 1.8E-11 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CDW54_RS00190 8114b1bd188b20ed44f0af69c34cf09b 642 PRINTS PR00941 Cadmium-transporting ATPase signature 43 55 1.8E-11 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CDW54_RS00190 8114b1bd188b20ed44f0af69c34cf09b 642 PRINTS PR00941 Cadmium-transporting ATPase signature 180 196 1.8E-11 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CDW54_RS00190 8114b1bd188b20ed44f0af69c34cf09b 642 SUPERFAMILY SSF81653 122 214 2.88E-23 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CDW54_RS00190 8114b1bd188b20ed44f0af69c34cf09b 642 Pfam PF00702 haloacid dehalogenase-like hydrolase 312 525 1.4E-33 T 28-03-2018 CDW54_RS00190 8114b1bd188b20ed44f0af69c34cf09b 642 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 317 323 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CDW54_RS00190 8114b1bd188b20ed44f0af69c34cf09b 642 Gene3D G3DSA:1.20.1110.10 60 333 1.0E-31 T 28-03-2018 CDW54_RS00190 8114b1bd188b20ed44f0af69c34cf09b 642 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 459 469 1.9E-27 T 28-03-2018 CDW54_RS00190 8114b1bd188b20ed44f0af69c34cf09b 642 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 437 448 1.9E-27 T 28-03-2018 CDW54_RS00190 8114b1bd188b20ed44f0af69c34cf09b 642 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 164 178 1.9E-27 T 28-03-2018 CDW54_RS00190 8114b1bd188b20ed44f0af69c34cf09b 642 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 315 329 1.9E-27 T 28-03-2018 CDW54_RS00190 8114b1bd188b20ed44f0af69c34cf09b 642 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 512 531 1.9E-27 T 28-03-2018 CDW54_RS00190 8114b1bd188b20ed44f0af69c34cf09b 642 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 535 547 1.9E-27 T 28-03-2018 CDW54_RS01980 14be3acdc05381bd5bcb7d24a2f6e844 900 Gene3D G3DSA:3.40.50.300 65 365 1.1E-22 T 28-03-2018 CDW54_RS01980 14be3acdc05381bd5bcb7d24a2f6e844 900 Pfam PF03610 PTS system fructose IIA component 548 662 1.6E-9 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CDW54_RS01980 14be3acdc05381bd5bcb7d24a2f6e844 900 Gene3D G3DSA:3.40.50.510 531 685 5.8E-25 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CDW54_RS01980 14be3acdc05381bd5bcb7d24a2f6e844 900 SUPERFAMILY SSF63520 800 896 3.92E-13 T 28-03-2018 IPR011608 PRD domain GO:0006355 CDW54_RS01980 14be3acdc05381bd5bcb7d24a2f6e844 900 SMART SM00382 106 255 4.0E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS01980 14be3acdc05381bd5bcb7d24a2f6e844 900 Gene3D G3DSA:1.10.1790.10 383 530 4.1E-18 T 28-03-2018 IPR011608 PRD domain GO:0006355 CDW54_RS01980 14be3acdc05381bd5bcb7d24a2f6e844 900 Pfam PF09339 IclR helix-turn-helix domain 7 42 1.6E-5 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CDW54_RS01980 14be3acdc05381bd5bcb7d24a2f6e844 900 SUPERFAMILY SSF52540 66 322 8.04E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS01980 14be3acdc05381bd5bcb7d24a2f6e844 900 SUPERFAMILY SSF53062 546 663 3.49E-15 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CDW54_RS01980 14be3acdc05381bd5bcb7d24a2f6e844 900 SUPERFAMILY SSF63520 437 531 1.18E-17 T 28-03-2018 IPR011608 PRD domain GO:0006355 CDW54_RS01980 14be3acdc05381bd5bcb7d24a2f6e844 900 Gene3D G3DSA:3.40.50.2300 686 780 6.3E-4 T 28-03-2018 CDW54_RS01980 14be3acdc05381bd5bcb7d24a2f6e844 900 Gene3D G3DSA:1.10.10.10 1 64 1.4E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS01980 14be3acdc05381bd5bcb7d24a2f6e844 900 Pfam PF00158 Sigma-54 interaction domain 83 244 7.7E-44 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CDW54_RS01980 14be3acdc05381bd5bcb7d24a2f6e844 900 SUPERFAMILY SSF46785 3 65 1.53E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS01980 14be3acdc05381bd5bcb7d24a2f6e844 900 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 179 194 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CDW54_RS01980 14be3acdc05381bd5bcb7d24a2f6e844 900 Gene3D G3DSA:1.10.1790.10 795 897 9.4E-11 T 28-03-2018 IPR011608 PRD domain GO:0006355 CDW54_RS01980 14be3acdc05381bd5bcb7d24a2f6e844 900 Pfam PF00874 PRD domain 447 531 1.7E-14 T 28-03-2018 IPR011608 PRD domain GO:0006355 CDW54_RS01980 14be3acdc05381bd5bcb7d24a2f6e844 900 Pfam PF00874 PRD domain 808 894 5.1E-11 T 28-03-2018 IPR011608 PRD domain GO:0006355 CDW54_RS04040 07e7018fa1089b5e99615cf618add2a0 291 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 229 284 5.7E-17 T 28-03-2018 IPR019264 Domain of unknown function DUF2179 CDW54_RS04040 07e7018fa1089b5e99615cf618add2a0 291 PIRSF PIRSF006483 1 290 7.9E-95 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT CDW54_RS04040 07e7018fa1089b5e99615cf618add2a0 291 Gene3D G3DSA:3.40.50.720 116 257 8.7E-4 T 28-03-2018 CDW54_RS04040 07e7018fa1089b5e99615cf618add2a0 291 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 18 223 1.5E-58 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT CDW54_RS07275 d5f9d743bf8d9abdb438c8ff698d3457 289 PIRSF PIRSF001359 1 282 8.0E-85 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CDW54_RS07275 d5f9d743bf8d9abdb438c8ff698d3457 289 Gene3D G3DSA:3.20.20.70 1 282 2.7E-90 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDW54_RS07275 d5f9d743bf8d9abdb438c8ff698d3457 289 SUPERFAMILY SSF51569 4 278 1.23E-87 T 28-03-2018 CDW54_RS07275 d5f9d743bf8d9abdb438c8ff698d3457 289 Pfam PF01116 Fructose-bisphosphate aldolase class-II 4 278 2.5E-89 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CDW54_RS07275 d5f9d743bf8d9abdb438c8ff698d3457 289 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 3 279 8.2E-78 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CDW54_RS07275 d5f9d743bf8d9abdb438c8ff698d3457 289 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 130 141 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CDW54_RS07070 decb604379d07295f358618ce56499c1 329 Pfam PF00248 Aldo/keto reductase family 27 328 3.9E-69 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CDW54_RS07070 decb604379d07295f358618ce56499c1 329 Gene3D G3DSA:3.20.20.100 14 329 1.2E-85 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CDW54_RS07070 decb604379d07295f358618ce56499c1 329 SUPERFAMILY SSF51430 12 327 2.36E-87 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CDW54_RS05455 bb2b3a15b93d48dd736426fdd4e0033a 155 PIRSF PIRSF010607 1 153 3.5E-63 T 28-03-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355|GO:0006950 CDW54_RS05455 bb2b3a15b93d48dd736426fdd4e0033a 155 Pfam PF05848 Firmicute transcriptional repressor of class III stress genes (CtsR) 5 149 1.8E-53 T 28-03-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355|GO:0006950 CDW54_RS08635 ccb32926ad86f0f60dc99caa211db3a1 613 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 218 232 - T 28-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 CDW54_RS08635 ccb32926ad86f0f60dc99caa211db3a1 613 Gene3D G3DSA:3.30.65.10 510 570 5.9E-7 T 28-03-2018 CDW54_RS08635 ccb32926ad86f0f60dc99caa211db3a1 613 Gene3D G3DSA:1.10.460.10 73 255 4.7E-33 T 28-03-2018 CDW54_RS08635 ccb32926ad86f0f60dc99caa211db3a1 613 Gene3D G3DSA:1.10.460.10 376 509 9.3E-20 T 28-03-2018 CDW54_RS08635 ccb32926ad86f0f60dc99caa211db3a1 613 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 104 122 6.1E-23 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CDW54_RS08635 ccb32926ad86f0f60dc99caa211db3a1 613 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 223 232 6.1E-23 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CDW54_RS08635 ccb32926ad86f0f60dc99caa211db3a1 613 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 12 25 6.1E-23 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CDW54_RS08635 ccb32926ad86f0f60dc99caa211db3a1 613 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 417 431 6.1E-23 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CDW54_RS08635 ccb32926ad86f0f60dc99caa211db3a1 613 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 301 317 6.1E-23 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CDW54_RS08635 ccb32926ad86f0f60dc99caa211db3a1 613 SMART SM00437 181 454 6.5E-83 T 28-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 CDW54_RS08635 ccb32926ad86f0f60dc99caa211db3a1 613 Gene3D G3DSA:2.70.20.10 262 375 2.3E-22 T 28-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CDW54_RS08635 ccb32926ad86f0f60dc99caa211db3a1 613 SUPERFAMILY SSF56712 2 504 1.83E-142 T 28-03-2018 IPR023405 DNA topoisomerase, type IA, core domain CDW54_RS08635 ccb32926ad86f0f60dc99caa211db3a1 613 Pfam PF01751 Toprim domain 2 47 1.9E-7 T 28-03-2018 IPR006171 TOPRIM domain CDW54_RS08635 ccb32926ad86f0f60dc99caa211db3a1 613 Pfam PF13342 C-terminal repeat of topoisomerase 552 611 2.6E-20 T 28-03-2018 IPR025589 Topoisomerase C-terminal repeat CDW54_RS08635 ccb32926ad86f0f60dc99caa211db3a1 613 Pfam PF01131 DNA topoisomerase 68 490 3.0E-106 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CDW54_RS08635 ccb32926ad86f0f60dc99caa211db3a1 613 SMART SM00436 39 134 1.9E-35 T 28-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 CDW54_RS08635 ccb32926ad86f0f60dc99caa211db3a1 613 Gene3D G3DSA:3.40.50.140 1 64 1.2E-16 T 28-03-2018 CDW54_RS08635 ccb32926ad86f0f60dc99caa211db3a1 613 TIGRFAM TIGR01056 topB: DNA topoisomerase III 2 610 6.1E-158 T 28-03-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 CDW54_RS11170 c2555106b3bd929f0ab54d432e31b3ba 643 SUPERFAMILY SSF52794 177 276 1.74E-37 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CDW54_RS11170 c2555106b3bd929f0ab54d432e31b3ba 643 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 52 68 - T 28-03-2018 IPR002178 PTS EIIA type-2 domain CDW54_RS11170 c2555106b3bd929f0ab54d432e31b3ba 643 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 296 635 4.2E-118 T 28-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 CDW54_RS11170 c2555106b3bd929f0ab54d432e31b3ba 643 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 8 133 1.6E-39 T 28-03-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 CDW54_RS11170 c2555106b3bd929f0ab54d432e31b3ba 643 SUPERFAMILY SSF55804 1 147 1.44E-41 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CDW54_RS11170 c2555106b3bd929f0ab54d432e31b3ba 643 Gene3D G3DSA:3.40.930.10 1 162 2.0E-43 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CDW54_RS11170 c2555106b3bd929f0ab54d432e31b3ba 643 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 179 268 2.4E-17 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CDW54_RS11170 c2555106b3bd929f0ab54d432e31b3ba 643 Pfam PF02378 Phosphotransferase system, EIIC 306 582 2.2E-22 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CDW54_RS11170 c2555106b3bd929f0ab54d432e31b3ba 643 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 178 260 1.4E-32 T 28-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 CDW54_RS11170 c2555106b3bd929f0ab54d432e31b3ba 643 Gene3D G3DSA:3.40.50.2300 176 272 6.5E-40 T 28-03-2018 CDW54_RS11170 c2555106b3bd929f0ab54d432e31b3ba 643 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 9 147 1.5E-35 T 28-03-2018 IPR002178 PTS EIIA type-2 domain CDW54_RS02625 4ce52bab0b62b75af1e5d6560b506dbe 442 PIRSF PIRSF005700 1 442 3.5E-183 T 28-03-2018 IPR004134 Peptidase C1B, bleomycin hydrolase GO:0004197|GO:0006508 Reactome: R-HSA-983168 CDW54_RS02625 4ce52bab0b62b75af1e5d6560b506dbe 442 Pfam PF03051 Peptidase C1-like family 4 439 9.8E-204 T 28-03-2018 IPR004134 Peptidase C1B, bleomycin hydrolase GO:0004197|GO:0006508 Reactome: R-HSA-983168 CDW54_RS02625 4ce52bab0b62b75af1e5d6560b506dbe 442 ProSitePatterns PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 361 371 - T 28-03-2018 IPR025660 Cysteine peptidase, histidine active site Reactome: R-HSA-2132295 CDW54_RS02625 4ce52bab0b62b75af1e5d6560b506dbe 442 Gene3D G3DSA:3.90.70.10 52 442 9.3E-135 T 28-03-2018 CDW54_RS02625 4ce52bab0b62b75af1e5d6560b506dbe 442 SUPERFAMILY SSF54001 9 442 5.97E-138 T 28-03-2018 CDW54_RS02625 4ce52bab0b62b75af1e5d6560b506dbe 442 ProSitePatterns PS00139 Eukaryotic thiol (cysteine) proteases cysteine active site. 63 74 - T 28-03-2018 IPR000169 Cysteine peptidase, cysteine active site CDW54_RS06170 1a52825c8921f1fc746d2fd0b39dc018 314 Pfam PF00005 ABC transporter 32 182 2.8E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS06170 1a52825c8921f1fc746d2fd0b39dc018 314 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 276 7.1E-7 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CDW54_RS06170 1a52825c8921f1fc746d2fd0b39dc018 314 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS06170 1a52825c8921f1fc746d2fd0b39dc018 314 Gene3D G3DSA:3.40.50.300 1 306 2.9E-71 T 28-03-2018 CDW54_RS06170 1a52825c8921f1fc746d2fd0b39dc018 314 SMART SM00382 40 232 1.2E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS06170 1a52825c8921f1fc746d2fd0b39dc018 314 SUPERFAMILY SSF52540 4 254 1.57E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS11860 1361152903f87c165a21dfca837fe3da 308 TIGRFAM TIGR03814 Gln_ase: glutaminase A 6 307 2.0E-117 T 28-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 CDW54_RS11860 1361152903f87c165a21dfca837fe3da 308 Hamap MF_00313 Glutaminase [glsA]. 2 307 44.238 T 28-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 CDW54_RS11860 1361152903f87c165a21dfca837fe3da 308 SUPERFAMILY SSF56601 5 307 1.09E-109 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CDW54_RS11860 1361152903f87c165a21dfca837fe3da 308 Gene3D G3DSA:3.40.710.10 2 308 1.6E-113 T 28-03-2018 CDW54_RS11860 1361152903f87c165a21dfca837fe3da 308 Pfam PF04960 Glutaminase 20 307 3.1E-110 T 28-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 CDW54_RS07210 75a52bae01d5c6f996c677ffc2a72f37 303 SUPERFAMILY SSF55048 115 183 7.98E-7 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CDW54_RS07210 75a52bae01d5c6f996c677ffc2a72f37 303 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 6 291 6.5E-12 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CDW54_RS07210 75a52bae01d5c6f996c677ffc2a72f37 303 SUPERFAMILY SSF52151 4 115 2.88E-44 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CDW54_RS07210 75a52bae01d5c6f996c677ffc2a72f37 303 SUPERFAMILY SSF52151 185 275 2.88E-44 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CDW54_RS07210 75a52bae01d5c6f996c677ffc2a72f37 303 Gene3D G3DSA:3.30.70.250 129 170 8.6E-9 T 28-03-2018 CDW54_RS07210 75a52bae01d5c6f996c677ffc2a72f37 303 Gene3D G3DSA:3.40.366.10 171 284 2.4E-16 T 28-03-2018 CDW54_RS07210 75a52bae01d5c6f996c677ffc2a72f37 303 Gene3D G3DSA:3.40.366.10 1 128 2.5E-21 T 28-03-2018 CDW54_RS07210 75a52bae01d5c6f996c677ffc2a72f37 303 Pfam PF00698 Acyl transferase domain 5 274 1.1E-19 T 28-03-2018 IPR014043 Acyl transferase CDW54_RS11290 cf6675a520a85ba69fbc9f06544ad0d8 431 PIRSF PIRSF000505 1 430 3.6E-124 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CDW54_RS11290 cf6675a520a85ba69fbc9f06544ad0d8 431 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 8 426 34.809 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CDW54_RS11290 cf6675a520a85ba69fbc9f06544ad0d8 431 Gene3D G3DSA:3.65.10.10 19 218 2.1E-58 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CDW54_RS11290 cf6675a520a85ba69fbc9f06544ad0d8 431 ProSitePatterns PS00104 EPSP synthase signature 1. 86 100 - T 28-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CDW54_RS11290 cf6675a520a85ba69fbc9f06544ad0d8 431 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 5 420 1.0E-127 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CDW54_RS11290 cf6675a520a85ba69fbc9f06544ad0d8 431 Gene3D G3DSA:3.65.10.10 219 426 4.4E-56 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CDW54_RS11290 cf6675a520a85ba69fbc9f06544ad0d8 431 SUPERFAMILY SSF55205 3 423 2.94E-139 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CDW54_RS11290 cf6675a520a85ba69fbc9f06544ad0d8 431 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 12 424 6.6E-134 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CDW54_RS11290 cf6675a520a85ba69fbc9f06544ad0d8 431 ProSitePatterns PS00885 EPSP synthase signature 2. 337 355 - T 28-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CDW54_RS02535 8b63db0f437d7f8f4406c266a3d5eb89 70 Pfam PF07288 Protein of unknown function (DUF1447) 2 69 1.1E-31 T 28-03-2018 IPR009907 Protein of unknown function DUF1447 CDW54_RS02535 8b63db0f437d7f8f4406c266a3d5eb89 70 ProDom PD055417 UPF0356 TRANSCRIPTIONAL REGULATOR SP0122 SH1862 BLI01669/BL01628 MW0973 LMOF2365_1049 BCE33L3734 SPYM3_1619/SPS0248 1 69 1.0E-33 T 28-03-2018 IPR009907 Protein of unknown function DUF1447 CDW54_RS02535 8b63db0f437d7f8f4406c266a3d5eb89 70 Hamap MF_01553 UPF0356 protein . 1 70 23.742 T 28-03-2018 IPR009907 Protein of unknown function DUF1447 CDW54_RS09045 e56735edbe91701d715d2965220efdc1 289 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 281 2.8E-54 T 28-03-2018 IPR000150 Cof family GO:0016787 CDW54_RS09045 e56735edbe91701d715d2965220efdc1 289 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 281 9.8E-60 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS09045 e56735edbe91701d715d2965220efdc1 289 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 254 2.4E-28 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CDW54_RS09045 e56735edbe91701d715d2965220efdc1 289 Gene3D G3DSA:3.40.50.1000 16 90 3.1E-18 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS09045 e56735edbe91701d715d2965220efdc1 289 Gene3D G3DSA:3.40.50.1000 1 15 0.25 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS09045 e56735edbe91701d715d2965220efdc1 289 SUPERFAMILY SSF56784 1 284 5.37E-66 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS09045 e56735edbe91701d715d2965220efdc1 289 ProSitePatterns PS01229 Hypothetical cof family signature 2. 235 257 - T 28-03-2018 CDW54_RS09045 e56735edbe91701d715d2965220efdc1 289 Gene3D G3DSA:3.30.1240.10 91 196 4.6E-25 T 28-03-2018 CDW54_RS09045 e56735edbe91701d715d2965220efdc1 289 Gene3D G3DSA:3.40.50.1000 197 289 6.3E-19 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS01985 5b3a7e7f08f6f161bb2e980e3c9ea32a 425 SUPERFAMILY SSF52540 73 352 6.06E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS01985 5b3a7e7f08f6f161bb2e980e3c9ea32a 425 Gene3D G3DSA:3.40.50.300 217 425 7.7E-30 T 28-03-2018 CDW54_RS01985 5b3a7e7f08f6f161bb2e980e3c9ea32a 425 SMART SM00490 251 332 6.4E-21 T 28-03-2018 IPR001650 Helicase, C-terminal CDW54_RS01985 5b3a7e7f08f6f161bb2e980e3c9ea32a 425 Pfam PF00271 Helicase conserved C-terminal domain 239 332 1.0E-16 T 28-03-2018 IPR001650 Helicase, C-terminal CDW54_RS01985 5b3a7e7f08f6f161bb2e980e3c9ea32a 425 SMART SM00487 20 216 7.1E-37 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CDW54_RS01985 5b3a7e7f08f6f161bb2e980e3c9ea32a 425 Gene3D G3DSA:3.40.50.300 7 216 7.5E-41 T 28-03-2018 CDW54_RS01985 5b3a7e7f08f6f161bb2e980e3c9ea32a 425 Pfam PF00270 DEAD/DEAH box helicase 27 188 9.2E-35 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CDW54_RS07870 0d17e086f2da575ca7ff4015923501d4 152 ProDom PD013172 LYASE SYNTHESIS LUXS AUTOINDUCER-2 PRODUCTION AUTOINDUCER S-RIBOSYLHOMOCYSTEINE AI-2 QUORUM SENSING 9 142 2.0E-76 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CDW54_RS07870 0d17e086f2da575ca7ff4015923501d4 152 Gene3D G3DSA:3.30.1360.80 4 151 8.4E-60 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CDW54_RS07870 0d17e086f2da575ca7ff4015923501d4 152 Pfam PF02664 S-Ribosylhomocysteinase (LuxS) 4 148 2.1E-56 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CDW54_RS07870 0d17e086f2da575ca7ff4015923501d4 152 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 50 68 3.2E-44 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CDW54_RS07870 0d17e086f2da575ca7ff4015923501d4 152 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 74 92 3.2E-44 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CDW54_RS07870 0d17e086f2da575ca7ff4015923501d4 152 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 115 134 3.2E-44 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CDW54_RS07870 0d17e086f2da575ca7ff4015923501d4 152 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 29 47 3.2E-44 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CDW54_RS07870 0d17e086f2da575ca7ff4015923501d4 152 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 6 24 3.2E-44 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CDW54_RS07870 0d17e086f2da575ca7ff4015923501d4 152 SUPERFAMILY SSF63411 2 150 8.24E-63 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CDW54_RS07870 0d17e086f2da575ca7ff4015923501d4 152 Hamap MF_00091 S-ribosylhomocysteine lyase [luxS]. 2 152 35.851 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CDW54_RS07870 0d17e086f2da575ca7ff4015923501d4 152 PIRSF PIRSF006160 2 152 1.5E-65 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CDW54_RS10850 3de41c34eb04b7516c090263df10f696 422 Pfam PF13180 PDZ domain 199 270 2.6E-12 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CDW54_RS10850 3de41c34eb04b7516c090263df10f696 422 SMART SM00228 186 262 8.1E-5 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CDW54_RS10850 3de41c34eb04b7516c090263df10f696 422 Gene3D G3DSA:2.30.42.10 201 291 3.7E-21 T 28-03-2018 CDW54_RS10850 3de41c34eb04b7516c090263df10f696 422 SUPERFAMILY SSF50156 175 271 6.57E-20 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CDW54_RS10850 3de41c34eb04b7516c090263df10f696 422 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 4 421 5.1E-93 T 28-03-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 CDW54_RS10850 3de41c34eb04b7516c090263df10f696 422 Pfam PF02163 Peptidase family M50 6 408 1.4E-82 T 28-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 CDW54_RS03915 0b6babfd3624cd1d4f2106244b5cb473 209 SUPERFAMILY SSF46894 142 207 3.4E-17 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDW54_RS03915 0b6babfd3624cd1d4f2106244b5cb473 209 SMART SM00448 2 114 8.3E-18 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDW54_RS03915 0b6babfd3624cd1d4f2106244b5cb473 209 SUPERFAMILY SSF52172 1 131 1.99E-24 T 28-03-2018 IPR011006 CheY-like superfamily CDW54_RS03915 0b6babfd3624cd1d4f2106244b5cb473 209 SMART SM00421 147 204 1.3E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDW54_RS03915 0b6babfd3624cd1d4f2106244b5cb473 209 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 203 4.2E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDW54_RS03915 0b6babfd3624cd1d4f2106244b5cb473 209 Gene3D G3DSA:3.40.50.2300 1 141 2.3E-26 T 28-03-2018 CDW54_RS03915 0b6babfd3624cd1d4f2106244b5cb473 209 Gene3D G3DSA:1.10.10.10 142 208 6.5E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS03915 0b6babfd3624cd1d4f2106244b5cb473 209 Pfam PF00072 Response regulator receiver domain 4 109 3.1E-20 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDW54_RS03915 0b6babfd3624cd1d4f2106244b5cb473 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 1.6E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDW54_RS03915 0b6babfd3624cd1d4f2106244b5cb473 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 1.6E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDW54_RS03915 0b6babfd3624cd1d4f2106244b5cb473 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 1.6E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDW54_RS05935 f912d01387e1ae0c9d52377c399e814f 277 Gene3D G3DSA:2.40.50.140 1 114 5.9E-49 T 28-03-2018 CDW54_RS05935 f912d01387e1ae0c9d52377c399e814f 277 Gene3D G3DSA:4.10.950.10 197 275 1.1E-34 T 28-03-2018 IPR014726 Ribosomal protein L2, domain 3 CDW54_RS05935 f912d01387e1ae0c9d52377c399e814f 277 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 275 48.417 T 28-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 CDW54_RS05935 f912d01387e1ae0c9d52377c399e814f 277 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 251 6.2E-58 T 28-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 CDW54_RS05935 f912d01387e1ae0c9d52377c399e814f 277 SMART SM01382 124 253 7.6E-92 T 28-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 CDW54_RS05935 f912d01387e1ae0c9d52377c399e814f 277 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 117 3.3E-34 T 28-03-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS05935 f912d01387e1ae0c9d52377c399e814f 277 PIRSF PIRSF002158 4 276 4.2E-99 T 28-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS05935 f912d01387e1ae0c9d52377c399e814f 277 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 28-03-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS05935 f912d01387e1ae0c9d52377c399e814f 277 SUPERFAMILY SSF50249 2 125 1.78E-50 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDW54_RS05935 f912d01387e1ae0c9d52377c399e814f 277 Gene3D G3DSA:2.30.30.30 119 195 6.4E-35 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 CDW54_RS05935 f912d01387e1ae0c9d52377c399e814f 277 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 275 1.7E-138 T 28-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 CDW54_RS05935 f912d01387e1ae0c9d52377c399e814f 277 SUPERFAMILY SSF50104 126 273 1.87E-60 T 28-03-2018 IPR008991 Translation protein SH3-like domain CDW54_RS05935 f912d01387e1ae0c9d52377c399e814f 277 SMART SM01383 42 118 4.1E-47 T 28-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS07975 1e4defa3acbbb40266c8da4302093989 343 SUPERFAMILY SSF74650 8 338 1.95E-99 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CDW54_RS07975 1e4defa3acbbb40266c8da4302093989 343 Gene3D G3DSA:2.70.98.10 1 343 5.4E-91 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CDW54_RS07975 1e4defa3acbbb40266c8da4302093989 343 Pfam PF01263 Aldose 1-epimerase 14 336 7.2E-75 T 28-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 CDW54_RS07975 1e4defa3acbbb40266c8da4302093989 343 ProSitePatterns PS00545 Aldose 1-epimerase putative active site. 167 176 - T 28-03-2018 IPR018052 Aldose 1-epimerase, conserved site KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 CDW54_RS07975 1e4defa3acbbb40266c8da4302093989 343 PIRSF PIRSF005096 1 341 6.0E-100 T 28-03-2018 IPR015443 Aldose 1-epimerase GO:0016853|GO:0019318 KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 CDW54_RS02595 751be24f445626cac2ee72c6a9fafcd6 186 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 10 123 4.1E-29 T 28-03-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 CDW54_RS02595 751be24f445626cac2ee72c6a9fafcd6 186 Gene3D G3DSA:1.10.3420.10 1 170 5.7E-47 T 28-03-2018 CDW54_RS09460 dc3a8b84d6da2430f8d40c6147a5e0e1 593 Gene3D G3DSA:2.40.50.100 116 167 6.9E-24 T 28-03-2018 CDW54_RS09460 dc3a8b84d6da2430f8d40c6147a5e0e1 593 SUPERFAMILY SSF47917 448 531 1.81E-24 T 28-03-2018 CDW54_RS09460 dc3a8b84d6da2430f8d40c6147a5e0e1 593 Hamap MF_00309 V-type ATP synthase alpha chain [atpA]. 1 588 51.002 T 28-03-2018 IPR022878 V-type ATP synthase catalytic alpha chain GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CDW54_RS09460 dc3a8b84d6da2430f8d40c6147a5e0e1 593 Gene3D G3DSA:1.10.1140.10 446 537 1.1E-30 T 28-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CDW54_RS09460 dc3a8b84d6da2430f8d40c6147a5e0e1 593 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 212 435 1.1E-93 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CDW54_RS09460 dc3a8b84d6da2430f8d40c6147a5e0e1 593 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 68 3.5E-12 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CDW54_RS09460 dc3a8b84d6da2430f8d40c6147a5e0e1 593 SUPERFAMILY SSF50615 2 70 1.41E-11 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CDW54_RS09460 dc3a8b84d6da2430f8d40c6147a5e0e1 593 Gene3D G3DSA:3.40.50.300 168 435 7.7E-102 T 28-03-2018 CDW54_RS09460 dc3a8b84d6da2430f8d40c6147a5e0e1 593 SUPERFAMILY SSF52540 178 437 2.34E-83 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS09460 dc3a8b84d6da2430f8d40c6147a5e0e1 593 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 426 435 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CDW54_RS09460 dc3a8b84d6da2430f8d40c6147a5e0e1 593 Pfam PF16886 ATPsynthase alpha/beta subunit N-term extension 84 203 1.6E-45 T 28-03-2018 IPR031686 ATPsynthase alpha/beta subunit, N-terminal extension KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CDW54_RS11390 e0b7c98eb95475a3d933c6188006768e 726 SUPERFAMILY SSF53098 318 467 6.83E-46 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS11390 e0b7c98eb95475a3d933c6188006768e 726 Pfam PF09371 Tex-like protein N-terminal domain 14 198 9.3E-71 T 28-03-2018 IPR018974 Tex-like protein, N-terminal CDW54_RS11390 e0b7c98eb95475a3d933c6188006768e 726 Gene3D G3DSA:1.10.3500.10 353 496 1.9E-38 T 28-03-2018 IPR023323 Tex-like domain CDW54_RS11390 e0b7c98eb95475a3d933c6188006768e 726 Pfam PF12836 Helix-hairpin-helix motif 489 553 9.5E-27 T 28-03-2018 CDW54_RS11390 e0b7c98eb95475a3d933c6188006768e 726 SUPERFAMILY SSF158832 5 317 2.09E-114 T 28-03-2018 CDW54_RS11390 e0b7c98eb95475a3d933c6188006768e 726 SUPERFAMILY SSF47781 558 633 5.78E-15 T 28-03-2018 IPR010994 RuvA domain 2-like CDW54_RS11390 e0b7c98eb95475a3d933c6188006768e 726 Gene3D G3DSA:2.40.50.140 641 723 1.1E-23 T 28-03-2018 CDW54_RS11390 e0b7c98eb95475a3d933c6188006768e 726 SMART SM00316 650 721 9.3E-24 T 28-03-2018 IPR022967 RNA-binding domain, S1 CDW54_RS11390 e0b7c98eb95475a3d933c6188006768e 726 Gene3D G3DSA:1.10.150.310 497 631 3.2E-46 T 28-03-2018 CDW54_RS11390 e0b7c98eb95475a3d933c6188006768e 726 SUPERFAMILY SSF50249 637 722 1.22E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDW54_RS11390 e0b7c98eb95475a3d933c6188006768e 726 SMART SM00732 322 422 3.4E-36 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CDW54_RS11390 e0b7c98eb95475a3d933c6188006768e 726 SUPERFAMILY SSF47781 468 556 1.05E-27 T 28-03-2018 IPR010994 RuvA domain 2-like CDW54_RS11390 e0b7c98eb95475a3d933c6188006768e 726 Gene3D G3DSA:1.10.3500.10 107 352 2.6E-84 T 28-03-2018 IPR023323 Tex-like domain CDW54_RS11390 e0b7c98eb95475a3d933c6188006768e 726 Pfam PF00575 S1 RNA binding domain 650 720 8.3E-17 T 28-03-2018 IPR003029 S1 domain GO:0003676 CDW54_RS11390 e0b7c98eb95475a3d933c6188006768e 726 Pfam PF16921 Tex protein YqgF-like domain 322 449 2.5E-54 T 28-03-2018 IPR032639 Tex protein, YqgF-like domain CDW54_RS11390 e0b7c98eb95475a3d933c6188006768e 726 Gene3D G3DSA:1.10.10.650 6 106 8.1E-33 T 28-03-2018 IPR023319 Tex-like protein, HTH domain CDW54_RS07660 dd5298e1f8d0158899cf591be42e4ae8 346 SUPERFAMILY SSF158472 74 124 4.84E-7 T 28-03-2018 CDW54_RS07660 dd5298e1f8d0158899cf591be42e4ae8 346 SMART SM00388 128 194 6.5E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDW54_RS07660 dd5298e1f8d0158899cf591be42e4ae8 346 PRINTS PR00344 Bacterial sensor protein C-terminal signature 332 345 8.3E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDW54_RS07660 dd5298e1f8d0158899cf591be42e4ae8 346 PRINTS PR00344 Bacterial sensor protein C-terminal signature 308 326 8.3E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDW54_RS07660 dd5298e1f8d0158899cf591be42e4ae8 346 PRINTS PR00344 Bacterial sensor protein C-terminal signature 275 289 8.3E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDW54_RS07660 dd5298e1f8d0158899cf591be42e4ae8 346 PRINTS PR00344 Bacterial sensor protein C-terminal signature 293 303 8.3E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDW54_RS07660 dd5298e1f8d0158899cf591be42e4ae8 346 Gene3D G3DSA:3.30.565.10 189 345 3.5E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS07660 dd5298e1f8d0158899cf591be42e4ae8 346 SUPERFAMILY SSF47384 111 195 1.22E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDW54_RS07660 dd5298e1f8d0158899cf591be42e4ae8 346 SMART SM00387 238 346 8.4E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS07660 dd5298e1f8d0158899cf591be42e4ae8 346 Gene3D G3DSA:1.10.287.130 118 188 9.2E-14 T 28-03-2018 CDW54_RS07660 dd5298e1f8d0158899cf591be42e4ae8 346 SUPERFAMILY SSF55874 184 344 2.23E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS07660 dd5298e1f8d0158899cf591be42e4ae8 346 SMART SM00304 74 127 6.6E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDW54_RS07660 dd5298e1f8d0158899cf591be42e4ae8 346 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 238 344 8.0E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS07660 dd5298e1f8d0158899cf591be42e4ae8 346 Pfam PF00512 His Kinase A (phospho-acceptor) domain 129 193 1.0E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDW54_RS02135 462dc87308e31a30755822da894c9054 445 Gene3D G3DSA:2.40.50.140 14 102 2.3E-7 T 28-03-2018 CDW54_RS02135 462dc87308e31a30755822da894c9054 445 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 7 351 6.9E-134 T 28-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 CDW54_RS02135 462dc87308e31a30755822da894c9054 445 Pfam PF13742 OB-fold nucleic acid binding domain 6 101 7.6E-28 T 28-03-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 CDW54_RS02135 462dc87308e31a30755822da894c9054 445 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 3 439 28.632 T 28-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 CDW54_RS02135 462dc87308e31a30755822da894c9054 445 Pfam PF02601 Exonuclease VII, large subunit 128 435 1.0E-95 T 28-03-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 CDW54_RS02640 b3a1719bb79af9dcde17a98f7201644c 209 SUPERFAMILY SSF53474 3 206 7.42E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CDW54_RS02640 b3a1719bb79af9dcde17a98f7201644c 209 Gene3D G3DSA:3.40.50.1820 3 209 6.2E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CDW54_RS02640 b3a1719bb79af9dcde17a98f7201644c 209 Pfam PF12146 Serine aminopeptidase, S33 44 125 4.4E-8 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CDW54_RS02010 093fd225cdcfe0a00d5a5d95061f45fd 508 SUPERFAMILY SSF55347 183 495 1.44E-111 T 28-03-2018 CDW54_RS02010 093fd225cdcfe0a00d5a5d95061f45fd 508 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 329 355 3.8E-47 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CDW54_RS02010 093fd225cdcfe0a00d5a5d95061f45fd 508 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 220 237 3.8E-47 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CDW54_RS02010 093fd225cdcfe0a00d5a5d95061f45fd 508 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 144 157 3.8E-47 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CDW54_RS02010 093fd225cdcfe0a00d5a5d95061f45fd 508 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 168 196 3.8E-47 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CDW54_RS02010 093fd225cdcfe0a00d5a5d95061f45fd 508 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 238 254 3.8E-47 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CDW54_RS02010 093fd225cdcfe0a00d5a5d95061f45fd 508 PIRSF PIRSF000110 1 496 7.5E-185 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CDW54_RS02010 093fd225cdcfe0a00d5a5d95061f45fd 508 Gene3D G3DSA:3.40.50.720 4 189 9.1E-65 T 28-03-2018 CDW54_RS02010 093fd225cdcfe0a00d5a5d95061f45fd 508 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 191 492 3.9E-111 T 28-03-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CDW54_RS02010 093fd225cdcfe0a00d5a5d95061f45fd 508 SUPERFAMILY SSF51735 5 191 3.74E-61 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS02010 093fd225cdcfe0a00d5a5d95061f45fd 508 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 6 492 1.5E-185 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CDW54_RS02010 093fd225cdcfe0a00d5a5d95061f45fd 508 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 11 188 2.1E-60 T 28-03-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CDW54_RS02010 093fd225cdcfe0a00d5a5d95061f45fd 508 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 178 184 - T 28-03-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CDW54_RS02010 093fd225cdcfe0a00d5a5d95061f45fd 508 Gene3D G3DSA:3.30.360.10 190 495 5.5E-120 T 28-03-2018 CDW54_RS02010 093fd225cdcfe0a00d5a5d95061f45fd 508 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 6 494 84.153 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CDW54_RS10860 96c15d2ddc110a964a87491a11121600 1450 Gene3D G3DSA:3.20.20.150 325 420 2.3E-5 T 28-03-2018 CDW54_RS10860 96c15d2ddc110a964a87491a11121600 1450 Pfam PF11490 DNA polymerase III polC-type N-terminus II 94 208 9.8E-24 T 28-03-2018 IPR024754 DNA polymerase III polC-like, N-terminal domain II KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDW54_RS10860 96c15d2ddc110a964a87491a11121600 1450 Gene3D G3DSA:3.30.420.10 421 573 1.9E-42 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS10860 96c15d2ddc110a964a87491a11121600 1450 SUPERFAMILY SSF50249 239 316 2.74E-10 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDW54_RS10860 96c15d2ddc110a964a87491a11121600 1450 SMART SM00481 339 406 1.6E-27 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CDW54_RS10860 96c15d2ddc110a964a87491a11121600 1450 Gene3D G3DSA:3.20.20.140 606 800 1.0E-19 T 28-03-2018 CDW54_RS10860 96c15d2ddc110a964a87491a11121600 1450 Pfam PF00929 Exonuclease 426 577 9.0E-37 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CDW54_RS10860 96c15d2ddc110a964a87491a11121600 1450 Gene3D G3DSA:2.40.50.140 223 324 6.4E-17 T 28-03-2018 CDW54_RS10860 96c15d2ddc110a964a87491a11121600 1450 TIGRFAM TIGR01405 polC_Gram_pos: DNA polymerase III, alpha subunit, Gram-positive type 234 1447 0.0 T 28-03-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDW54_RS10860 96c15d2ddc110a964a87491a11121600 1450 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 829 1258 9.3E-101 T 28-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDW54_RS10860 96c15d2ddc110a964a87491a11121600 1450 Hamap MF_00356 DNA polymerase III PolC-type [polC]. 1 1450 442.378 T 28-03-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDW54_RS10860 96c15d2ddc110a964a87491a11121600 1450 SMART SM00479 424 590 3.1E-46 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CDW54_RS10860 96c15d2ddc110a964a87491a11121600 1450 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 419 638 3.2E-42 T 28-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDW54_RS10860 96c15d2ddc110a964a87491a11121600 1450 SUPERFAMILY SSF89550 350 432 4.32E-5 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CDW54_RS10860 96c15d2ddc110a964a87491a11121600 1450 Pfam PF02811 PHP domain 340 698 1.2E-52 T 28-03-2018 IPR004013 PHP domain GO:0003824 CDW54_RS10860 96c15d2ddc110a964a87491a11121600 1450 Pfam PF14579 Helix-hairpin-helix motif 1365 1439 8.3E-9 T 28-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDW54_RS10860 96c15d2ddc110a964a87491a11121600 1450 Gene3D G3DSA:1.20.5.140 574 594 1.8E-9 T 28-03-2018 CDW54_RS10860 96c15d2ddc110a964a87491a11121600 1450 SUPERFAMILY SSF53098 424 881 4.23E-105 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS10860 96c15d2ddc110a964a87491a11121600 1450 Gene3D G3DSA:1.10.150.280 1322 1435 0.0017 T 28-03-2018 CDW54_RS10860 96c15d2ddc110a964a87491a11121600 1450 Pfam PF14480 DNA polymerase III polC-type N-terminus I 7 80 1.5E-19 T 28-03-2018 IPR028112 DNA polymerase III polC-type, N-terminal domain I KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDW54_RS10860 96c15d2ddc110a964a87491a11121600 1450 SUPERFAMILY SSF160975 1388 1430 7.19E-5 T 28-03-2018 CDW54_RS03480 d0cf4afb4509dec2597aea1e4de9d890 575 SUPERFAMILY SSF52540 324 568 5.66E-83 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS03480 d0cf4afb4509dec2597aea1e4de9d890 575 SUPERFAMILY SSF90123 12 316 8.89E-71 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CDW54_RS03480 d0cf4afb4509dec2597aea1e4de9d890 575 Gene3D G3DSA:1.20.1560.10 1 311 9.7E-75 T 28-03-2018 CDW54_RS03480 d0cf4afb4509dec2597aea1e4de9d890 575 Pfam PF00005 ABC transporter 349 496 5.7E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS03480 d0cf4afb4509dec2597aea1e4de9d890 575 Gene3D G3DSA:3.40.50.300 318 574 8.1E-70 T 28-03-2018 CDW54_RS03480 d0cf4afb4509dec2597aea1e4de9d890 575 Pfam PF00664 ABC transporter transmembrane region 15 281 4.0E-40 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CDW54_RS03480 d0cf4afb4509dec2597aea1e4de9d890 575 SMART SM00382 358 550 2.0E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS03480 d0cf4afb4509dec2597aea1e4de9d890 575 ProSitePatterns PS00211 ABC transporters family signature. 470 484 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS11470 6cdb1769ff8507bced9c3e76c4db9dcf 410 TIGRFAM TIGR01882 peptidase-T: peptidase T 2 408 2.2E-204 T 28-03-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 CDW54_RS11470 6cdb1769ff8507bced9c3e76c4db9dcf 410 Gene3D G3DSA:3.40.630.10 2 409 1.8E-47 T 28-03-2018 CDW54_RS11470 6cdb1769ff8507bced9c3e76c4db9dcf 410 Pfam PF07687 Peptidase dimerisation domain 210 305 8.9E-12 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CDW54_RS11470 6cdb1769ff8507bced9c3e76c4db9dcf 410 PIRSF PIRSF037215 1 410 7.5E-190 T 28-03-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 CDW54_RS11470 6cdb1769ff8507bced9c3e76c4db9dcf 410 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 75 84 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CDW54_RS11470 6cdb1769ff8507bced9c3e76c4db9dcf 410 Pfam PF01546 Peptidase family M20/M25/M40 142 404 1.9E-14 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CDW54_RS11470 6cdb1769ff8507bced9c3e76c4db9dcf 410 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 141 180 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CDW54_RS11470 6cdb1769ff8507bced9c3e76c4db9dcf 410 SUPERFAMILY SSF53187 2 213 1.06E-74 T 28-03-2018 CDW54_RS11470 6cdb1769ff8507bced9c3e76c4db9dcf 410 SUPERFAMILY SSF53187 325 405 1.06E-74 T 28-03-2018 CDW54_RS11470 6cdb1769ff8507bced9c3e76c4db9dcf 410 Hamap MF_00550 Peptidase T [pepT]. 2 407 58.405 T 28-03-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 CDW54_RS11470 6cdb1769ff8507bced9c3e76c4db9dcf 410 SUPERFAMILY SSF55031 212 323 2.79E-42 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CDW54_RS09650 127918e3befc2425f4bbfbde4e896955 518 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 371 493 1.2E-48 T 28-03-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS09650 127918e3befc2425f4bbfbde4e896955 518 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 499 50.73 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS09650 127918e3befc2425f4bbfbde4e896955 518 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 355 364 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CDW54_RS09650 127918e3befc2425f4bbfbde4e896955 518 SUPERFAMILY SSF50615 10 94 5.76E-29 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CDW54_RS09650 127918e3befc2425f4bbfbde4e896955 518 Gene3D G3DSA:3.40.50.300 83 364 1.0E-115 T 28-03-2018 CDW54_RS09650 127918e3befc2425f4bbfbde4e896955 518 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 364 1.6E-70 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CDW54_RS09650 127918e3befc2425f4bbfbde4e896955 518 PIRSF PIRSF039088 1 501 2.1E-247 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS09650 127918e3befc2425f4bbfbde4e896955 518 SUPERFAMILY SSF52540 95 370 1.2E-96 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS09650 127918e3befc2425f4bbfbde4e896955 518 SUPERFAMILY SSF47917 372 499 9.16E-50 T 28-03-2018 CDW54_RS09650 127918e3befc2425f4bbfbde4e896955 518 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 25 92 4.9E-20 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CDW54_RS09650 127918e3befc2425f4bbfbde4e896955 518 Gene3D G3DSA:1.20.150.20 373 498 4.0E-51 T 28-03-2018 CDW54_RS09650 127918e3befc2425f4bbfbde4e896955 518 Gene3D G3DSA:2.40.30.20 3 82 1.3E-35 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS09650 127918e3befc2425f4bbfbde4e896955 518 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 498 5.6E-254 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS08825 61aac3fbde299e9360c33f9f2f12177f 323 SUPERFAMILY SSF47413 1 58 1.17E-12 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDW54_RS08825 61aac3fbde299e9360c33f9f2f12177f 323 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 60 314 5.3E-19 T 28-03-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain CDW54_RS08825 61aac3fbde299e9360c33f9f2f12177f 323 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 28-03-2018 CDW54_RS08825 61aac3fbde299e9360c33f9f2f12177f 323 SUPERFAMILY SSF53822 57 310 9.42E-51 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CDW54_RS08825 61aac3fbde299e9360c33f9f2f12177f 323 Gene3D G3DSA:3.40.50.2300 55 173 5.0E-27 T 28-03-2018 CDW54_RS08825 61aac3fbde299e9360c33f9f2f12177f 323 SMART SM00354 1 70 1.1E-18 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS08825 61aac3fbde299e9360c33f9f2f12177f 323 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 47 4.9E-11 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS08825 61aac3fbde299e9360c33f9f2f12177f 323 Gene3D G3DSA:3.40.50.2300 174 307 2.7E-29 T 28-03-2018 CDW54_RS08825 61aac3fbde299e9360c33f9f2f12177f 323 Gene3D G3DSA:1.10.260.40 3 54 1.9E-14 T 28-03-2018 CDW54_RS08825 61aac3fbde299e9360c33f9f2f12177f 323 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 5.3E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS08825 61aac3fbde299e9360c33f9f2f12177f 323 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 5.3E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS00915 c7bcac5114373a478741c76fd6cbcf81 436 Pfam PF01926 50S ribosome-binding GTPase 6 120 2.0E-25 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CDW54_RS00915 c7bcac5114373a478741c76fd6cbcf81 436 Pfam PF01926 50S ribosome-binding GTPase 178 295 3.1E-25 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CDW54_RS00915 c7bcac5114373a478741c76fd6cbcf81 436 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 6 26 1.4E-5 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CDW54_RS00915 c7bcac5114373a478741c76fd6cbcf81 436 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 73 91 1.4E-5 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CDW54_RS00915 c7bcac5114373a478741c76fd6cbcf81 436 Gene3D G3DSA:1.20.120.430 242 361 6.0E-17 T 28-03-2018 CDW54_RS00915 c7bcac5114373a478741c76fd6cbcf81 436 Gene3D G3DSA:1.20.120.430 1 71 1.3E-18 T 28-03-2018 CDW54_RS00915 c7bcac5114373a478741c76fd6cbcf81 436 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 353 433 3.0E-32 T 28-03-2018 IPR032859 GTPase Der, C-terminal KH-domain-like CDW54_RS00915 c7bcac5114373a478741c76fd6cbcf81 436 SUPERFAMILY SSF52540 138 434 7.46E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS00915 c7bcac5114373a478741c76fd6cbcf81 436 SUPERFAMILY SSF52540 4 169 4.86E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS00915 c7bcac5114373a478741c76fd6cbcf81 436 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 4 431 3.4E-175 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CDW54_RS00915 c7bcac5114373a478741c76fd6cbcf81 436 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 174 344 2.8E-29 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CDW54_RS00915 c7bcac5114373a478741c76fd6cbcf81 436 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 2 125 3.9E-24 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CDW54_RS00915 c7bcac5114373a478741c76fd6cbcf81 436 Hamap MF_00195 GTPase Der [der]. 3 436 40.483 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CDW54_RS00915 c7bcac5114373a478741c76fd6cbcf81 436 Gene3D G3DSA:1.20.120.430 72 241 9.4E-44 T 28-03-2018 CDW54_RS00915 c7bcac5114373a478741c76fd6cbcf81 436 Gene3D G3DSA:3.30.300.20 362 434 9.8E-34 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CDW54_RS00915 c7bcac5114373a478741c76fd6cbcf81 436 PIRSF PIRSF006485 2 436 1.2E-170 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CDW54_RS11955 ecf65a72a62fa4b018297c443e4fa965 429 Pfam PF00746 LPXTG cell wall anchor motif 386 422 2.2E-4 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CDW54_RS11955 ecf65a72a62fa4b018297c443e4fa965 429 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 392 424 1.8E-5 T 28-03-2018 CDW54_RS01020 2e95f1d7e9e7c49b6ebba459cb2efd7c 797 Pfam PF00122 E1-E2 ATPase 118 297 3.7E-42 T 28-03-2018 CDW54_RS01020 2e95f1d7e9e7c49b6ebba459cb2efd7c 797 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 90 498 3.8E-44 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDW54_RS01020 2e95f1d7e9e7c49b6ebba459cb2efd7c 797 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 516 639 6.4E-27 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDW54_RS01020 2e95f1d7e9e7c49b6ebba459cb2efd7c 797 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 83 103 7.8E-8 T 28-03-2018 CDW54_RS01020 2e95f1d7e9e7c49b6ebba459cb2efd7c 797 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 236 258 7.8E-8 T 28-03-2018 CDW54_RS01020 2e95f1d7e9e7c49b6ebba459cb2efd7c 797 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 756 776 7.8E-8 T 28-03-2018 CDW54_RS01020 2e95f1d7e9e7c49b6ebba459cb2efd7c 797 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 310 331 7.8E-8 T 28-03-2018 CDW54_RS01020 2e95f1d7e9e7c49b6ebba459cb2efd7c 797 SUPERFAMILY SSF81653 121 210 2.75E-23 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CDW54_RS01020 2e95f1d7e9e7c49b6ebba459cb2efd7c 797 Gene3D G3DSA:2.70.150.10 18 215 1.7E-33 T 28-03-2018 CDW54_RS01020 2e95f1d7e9e7c49b6ebba459cb2efd7c 797 Pfam PF00702 haloacid dehalogenase-like hydrolase 313 565 3.1E-28 T 28-03-2018 CDW54_RS01020 2e95f1d7e9e7c49b6ebba459cb2efd7c 797 Gene3D G3DSA:3.40.1110.10 274 462 6.4E-15 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CDW54_RS01020 2e95f1d7e9e7c49b6ebba459cb2efd7c 797 Gene3D G3DSA:1.20.1110.10 578 785 3.7E-18 T 28-03-2018 CDW54_RS01020 2e95f1d7e9e7c49b6ebba459cb2efd7c 797 Gene3D G3DSA:3.40.50.1000 463 577 1.3E-25 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS01020 2e95f1d7e9e7c49b6ebba459cb2efd7c 797 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 452 463 1.6E-20 T 28-03-2018 CDW54_RS01020 2e95f1d7e9e7c49b6ebba459cb2efd7c 797 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 574 586 1.6E-20 T 28-03-2018 CDW54_RS01020 2e95f1d7e9e7c49b6ebba459cb2efd7c 797 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 166 180 1.6E-20 T 28-03-2018 CDW54_RS01020 2e95f1d7e9e7c49b6ebba459cb2efd7c 797 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 317 331 1.6E-20 T 28-03-2018 CDW54_RS01020 2e95f1d7e9e7c49b6ebba459cb2efd7c 797 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 551 570 1.6E-20 T 28-03-2018 CDW54_RS01020 2e95f1d7e9e7c49b6ebba459cb2efd7c 797 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 474 484 1.6E-20 T 28-03-2018 CDW54_RS01020 2e95f1d7e9e7c49b6ebba459cb2efd7c 797 SUPERFAMILY SSF56784 315 335 1.37E-39 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS01020 2e95f1d7e9e7c49b6ebba459cb2efd7c 797 SUPERFAMILY SSF56784 412 642 1.37E-39 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS01020 2e95f1d7e9e7c49b6ebba459cb2efd7c 797 SUPERFAMILY SSF81665 600 779 7.98E-53 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CDW54_RS01020 2e95f1d7e9e7c49b6ebba459cb2efd7c 797 SUPERFAMILY SSF81665 25 120 7.98E-53 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CDW54_RS01020 2e95f1d7e9e7c49b6ebba459cb2efd7c 797 SUPERFAMILY SSF81665 217 311 7.98E-53 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CDW54_RS01020 2e95f1d7e9e7c49b6ebba459cb2efd7c 797 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 319 325 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CDW54_RS08025 faa1291d2d2a990043922fd052609fb1 383 SUPERFAMILY SSF54862 167 276 1.51E-13 T 28-03-2018 CDW54_RS08025 faa1291d2d2a990043922fd052609fb1 383 Gene3D G3DSA:3.30.70.20 47 193 0.0012 T 28-03-2018 CDW54_RS08025 faa1291d2d2a990043922fd052609fb1 383 SUPERFAMILY SSF48371 291 367 8.06E-9 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CDW54_RS08025 faa1291d2d2a990043922fd052609fb1 383 Gene3D G3DSA:3.30.70.20 194 239 2.5E-7 T 28-03-2018 CDW54_RS08025 faa1291d2d2a990043922fd052609fb1 383 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 189 200 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CDW54_RS08025 faa1291d2d2a990043922fd052609fb1 383 Pfam PF13484 4Fe-4S double cluster binding domain 189 251 1.8E-16 T 28-03-2018 CDW54_RS08025 faa1291d2d2a990043922fd052609fb1 383 Gene3D G3DSA:1.25.10.10 240 372 2.0E-10 T 28-03-2018 IPR011989 Armadillo-like helical CDW54_RS08025 faa1291d2d2a990043922fd052609fb1 383 Pfam PF13646 HEAT repeats 301 371 6.3E-9 T 28-03-2018 CDW54_RS08025 faa1291d2d2a990043922fd052609fb1 383 SMART SM00567 E-Z type HEAT repeats 330 362 65.0 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CDW54_RS08025 faa1291d2d2a990043922fd052609fb1 383 SMART SM00567 E-Z type HEAT repeats 299 328 2.8 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CDW54_RS08025 faa1291d2d2a990043922fd052609fb1 383 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 7 342 5.4E-115 T 28-03-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 CDW54_RS08025 faa1291d2d2a990043922fd052609fb1 383 Pfam PF08331 Domain of unknown function (DUF1730) 54 136 3.3E-16 T 28-03-2018 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 CDW54_RS00020 313955d447bc00539e012dbaf4c034b9 245 Gene3D G3DSA:3.40.50.300 1 243 8.1E-74 T 28-03-2018 CDW54_RS00020 313955d447bc00539e012dbaf4c034b9 245 SUPERFAMILY SSF52540 3 237 2.23E-76 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS00020 313955d447bc00539e012dbaf4c034b9 245 PIRSF PIRSF039085 1 244 4.5E-106 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CDW54_RS00020 313955d447bc00539e012dbaf4c034b9 245 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS00020 313955d447bc00539e012dbaf4c034b9 245 Pfam PF00005 ABC transporter 19 167 1.0E-37 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS00020 313955d447bc00539e012dbaf4c034b9 245 SMART SM00382 28 215 7.3E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS04405 ad17e5c3c28b1915e90bec3be4f6d9ee 429 Pfam PF06824 Metal-independent alpha-mannosidase (GH125) 27 420 4.6E-149 T 28-03-2018 IPR008313 Metal-independent alpha-mannosidase CDW54_RS04405 ad17e5c3c28b1915e90bec3be4f6d9ee 429 SMART SM01149 25 421 1.8E-265 T 28-03-2018 IPR008313 Metal-independent alpha-mannosidase CDW54_RS04405 ad17e5c3c28b1915e90bec3be4f6d9ee 429 Gene3D G3DSA:1.50.10.10 7 428 4.9E-157 T 28-03-2018 CDW54_RS04405 ad17e5c3c28b1915e90bec3be4f6d9ee 429 SUPERFAMILY SSF48208 4 426 2.78E-177 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CDW54_RS04405 ad17e5c3c28b1915e90bec3be4f6d9ee 429 PIRSF PIRSF028846 1 429 7.8E-213 T 28-03-2018 IPR008313 Metal-independent alpha-mannosidase CDW54_RS03475 61b81aaf1dd4715a0b208ca1b8c3d102 630 SUPERFAMILY SSF90123 40 370 1.44E-84 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CDW54_RS03475 61b81aaf1dd4715a0b208ca1b8c3d102 630 Pfam PF00005 ABC transporter 406 553 4.0E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS03475 61b81aaf1dd4715a0b208ca1b8c3d102 630 SUPERFAMILY SSF52540 382 624 1.15E-91 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS03475 61b81aaf1dd4715a0b208ca1b8c3d102 630 Gene3D G3DSA:1.20.1560.10 23 372 8.2E-89 T 28-03-2018 CDW54_RS03475 61b81aaf1dd4715a0b208ca1b8c3d102 630 Pfam PF00664 ABC transporter transmembrane region 53 341 6.9E-55 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CDW54_RS03475 61b81aaf1dd4715a0b208ca1b8c3d102 630 ProSitePatterns PS00211 ABC transporters family signature. 525 539 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS03475 61b81aaf1dd4715a0b208ca1b8c3d102 630 Gene3D G3DSA:3.40.50.300 373 629 9.8E-76 T 28-03-2018 CDW54_RS03475 61b81aaf1dd4715a0b208ca1b8c3d102 630 SMART SM00382 413 599 2.1E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS06215 562af6f63f22fe5b7110ece7dc5e7b4f 755 Pfam PF02655 ATP-grasp domain 487 708 3.1E-7 T 28-03-2018 IPR003806 ATP-grasp fold, DUF201-type GO:0005524|GO:0046872 CDW54_RS06215 562af6f63f22fe5b7110ece7dc5e7b4f 755 SUPERFAMILY SSF55931 2 458 1.18E-139 T 28-03-2018 CDW54_RS06215 562af6f63f22fe5b7110ece7dc5e7b4f 755 Pfam PF04262 Glutamate-cysteine ligase 11 324 2.7E-79 T 28-03-2018 IPR007370 Glutamate--cysteine ligase GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CDW54_RS06215 562af6f63f22fe5b7110ece7dc5e7b4f 755 Gene3D G3DSA:3.30.1490.20 484 560 8.7E-10 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CDW54_RS06215 562af6f63f22fe5b7110ece7dc5e7b4f 755 TIGRFAM TIGR01435 glu_cys_lig_rel: glutamate--cysteine ligase/glutathione synthase 14 751 0.0 T 28-03-2018 IPR006335 Glutathione biosynthesis bifunctional protein GshAB GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2+6.3.2.3|KEGG: 00480+6.3.2.2+6.3.2.3|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CDW54_RS06215 562af6f63f22fe5b7110ece7dc5e7b4f 755 Hamap MF_00782 Glutathione biosynthesis bifunctional protein GshAB [gshAB]. 1 755 373.407 T 28-03-2018 IPR006335 Glutathione biosynthesis bifunctional protein GshAB GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2+6.3.2.3|KEGG: 00480+6.3.2.2+6.3.2.3|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CDW54_RS06215 562af6f63f22fe5b7110ece7dc5e7b4f 755 Gene3D G3DSA:3.30.470.20 561 748 3.8E-22 T 28-03-2018 CDW54_RS06215 562af6f63f22fe5b7110ece7dc5e7b4f 755 SUPERFAMILY SSF56059 488 621 3.21E-28 T 28-03-2018 CDW54_RS06215 562af6f63f22fe5b7110ece7dc5e7b4f 755 SUPERFAMILY SSF56059 657 751 3.21E-28 T 28-03-2018 CDW54_RS06725 aa6cc66147406269c18bcc8316fca102 354 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 2 326 2.2E-114 T 28-03-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 CDW54_RS06725 aa6cc66147406269c18bcc8316fca102 354 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 1 327 35.448 T 28-03-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 CDW54_RS06725 aa6cc66147406269c18bcc8316fca102 354 Pfam PF01070 FMN-dependent dehydrogenase 160 323 7.5E-21 T 28-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 CDW54_RS06725 aa6cc66147406269c18bcc8316fca102 354 Gene3D G3DSA:3.20.20.70 1 339 8.1E-68 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDW54_RS06725 aa6cc66147406269c18bcc8316fca102 354 SUPERFAMILY SSF51395 20 344 1.83E-80 T 28-03-2018 CDW54_RS06725 aa6cc66147406269c18bcc8316fca102 354 PIRSF PIRSF003314 1 337 1.9E-120 T 28-03-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 CDW54_RS03640 5bf719ea0a9b18c22a48739cd00bbbe7 94 ProSitePatterns PS00681 Chaperonins cpn10 signature. 2 26 - T 28-03-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 CDW54_RS03640 5bf719ea0a9b18c22a48739cd00bbbe7 94 Gene3D G3DSA:2.30.33.40 1 94 1.0E-36 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CDW54_RS03640 5bf719ea0a9b18c22a48739cd00bbbe7 94 Hamap MF_00580 10 kDa chaperonin [groS]. 1 94 25.377 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CDW54_RS03640 5bf719ea0a9b18c22a48739cd00bbbe7 94 SUPERFAMILY SSF50129 2 94 2.64E-33 T 28-03-2018 IPR011032 GroES-like CDW54_RS03640 5bf719ea0a9b18c22a48739cd00bbbe7 94 Pfam PF00166 Chaperonin 10 Kd subunit 2 93 5.2E-35 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CDW54_RS03640 5bf719ea0a9b18c22a48739cd00bbbe7 94 PRINTS PR00297 10kDa chaperonin signature 24 45 3.1E-27 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CDW54_RS03640 5bf719ea0a9b18c22a48739cd00bbbe7 94 PRINTS PR00297 10kDa chaperonin signature 2 17 3.1E-27 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CDW54_RS03640 5bf719ea0a9b18c22a48739cd00bbbe7 94 PRINTS PR00297 10kDa chaperonin signature 59 71 3.1E-27 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CDW54_RS03640 5bf719ea0a9b18c22a48739cd00bbbe7 94 PRINTS PR00297 10kDa chaperonin signature 80 93 3.1E-27 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CDW54_RS03640 5bf719ea0a9b18c22a48739cd00bbbe7 94 SMART SM00883 1 93 1.8E-48 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CDW54_RS11030 66033f7f80d9720d79f7393f341c6108 294 Gene3D G3DSA:3.40.50.300 2 164 1.4E-9 T 28-03-2018 CDW54_RS11030 66033f7f80d9720d79f7393f341c6108 294 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 5 286 41.992 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 CDW54_RS11030 66033f7f80d9720d79f7393f341c6108 294 SUPERFAMILY SSF52540 7 160 1.09E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS11030 66033f7f80d9720d79f7393f341c6108 294 Pfam PF03668 P-loop ATPase protein family 5 287 4.5E-112 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 CDW54_RS11030 66033f7f80d9720d79f7393f341c6108 294 PIRSF PIRSF005052 5 289 9.2E-112 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 CDW54_RS00415 7cac26dfcc78ef29841014997d6368c7 84 SUPERFAMILY SSF82697 1 79 3.31E-28 T 28-03-2018 CDW54_RS00415 7cac26dfcc78ef29841014997d6368c7 84 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 11 81 5.0E-35 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CDW54_RS00415 7cac26dfcc78ef29841014997d6368c7 84 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 4 78 1.2E-29 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CDW54_RS00415 7cac26dfcc78ef29841014997d6368c7 84 Gene3D G3DSA:3.30.1280.10 2 79 2.0E-27 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CDW54_RS00415 7cac26dfcc78ef29841014997d6368c7 84 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 2 78 20.01 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CDW54_RS00415 7cac26dfcc78ef29841014997d6368c7 84 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 2 80 4.5E-25 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CDW54_RS11520 4280dbe343878dd6f0ff5de6f9bf39a6 164 Gene3D G3DSA:3.40.50.450 1 158 6.4E-38 T 28-03-2018 CDW54_RS11520 4280dbe343878dd6f0ff5de6f9bf39a6 164 Pfam PF05014 Nucleoside 2-deoxyribosyltransferase 3 105 3.6E-23 T 28-03-2018 IPR007710 Nucleoside 2-deoxyribosyltransferase GO:0009159|GO:0050144|GO:0070694 Reactome: R-HSA-74259 CDW54_RS11520 4280dbe343878dd6f0ff5de6f9bf39a6 164 SUPERFAMILY SSF52309 1 142 5.49E-33 T 28-03-2018 CDW54_RS04315 df81599676d4666396c737797a13a952 502 SUPERFAMILY SSF53850 20 500 5.38E-89 T 28-03-2018 CDW54_RS04315 df81599676d4666396c737797a13a952 502 Pfam PF13416 Bacterial extracellular solute-binding protein 61 289 1.7E-15 T 28-03-2018 CDW54_RS04315 df81599676d4666396c737797a13a952 502 Gene3D G3DSA:3.40.190.10 155 502 2.4E-47 T 28-03-2018 CDW54_RS11775 4efc4fb36df7e4b03221939d4231c471 312 SUPERFAMILY SSF143865 13 245 2.62E-24 T 28-03-2018 CDW54_RS11775 4efc4fb36df7e4b03221939d4231c471 312 SUPERFAMILY SSF144083 246 308 5.75E-12 T 28-03-2018 CDW54_RS11775 4efc4fb36df7e4b03221939d4231c471 312 Gene3D G3DSA:1.20.58.340 128 243 7.1E-8 T 28-03-2018 CDW54_RS11775 4efc4fb36df7e4b03221939d4231c471 312 Gene3D G3DSA:1.20.58.340 244 311 9.2E-9 T 28-03-2018 CDW54_RS11775 4efc4fb36df7e4b03221939d4231c471 312 Gene3D G3DSA:3.30.460.20 5 121 1.0E-8 T 28-03-2018 CDW54_RS11775 4efc4fb36df7e4b03221939d4231c471 312 Pfam PF01544 CorA-like Mg2+ transporter protein 18 306 8.2E-48 T 28-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 CDW54_RS09475 2cc918ebb50fd1dee7695c317ed456ef 451 Pfam PF02386 Cation transport protein 42 429 3.3E-58 T 28-03-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 CDW54_RS09475 2cc918ebb50fd1dee7695c317ed456ef 451 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 32 420 1.1E-120 T 28-03-2018 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 CDW54_RS01770 af4d1de231aee5ee32121f1aac80ee75 391 Gene3D G3DSA:3.30.160.60 359 391 1.5E-10 T 28-03-2018 CDW54_RS01770 af4d1de231aee5ee32121f1aac80ee75 391 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 41 390 7.1E-84 T 28-03-2018 IPR003770 Endolytic murein transglycosylase CDW54_RS01770 af4d1de231aee5ee32121f1aac80ee75 391 Gene3D G3DSA:3.30.160.60 114 144 1.2E-6 T 28-03-2018 CDW54_RS01770 af4d1de231aee5ee32121f1aac80ee75 391 Pfam PF02618 YceG-like family 81 386 7.9E-75 T 28-03-2018 IPR003770 Endolytic murein transglycosylase CDW54_RS01770 af4d1de231aee5ee32121f1aac80ee75 391 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 41 390 32.631 T 28-03-2018 IPR003770 Endolytic murein transglycosylase CDW54_RS01405 740b6d9f62e2277f18b110e0fdd0d1d2 594 SUPERFAMILY SSF52935 354 554 5.04E-49 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CDW54_RS01405 740b6d9f62e2277f18b110e0fdd0d1d2 594 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 481 1.0E-172 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CDW54_RS01405 740b6d9f62e2277f18b110e0fdd0d1d2 594 Gene3D G3DSA:3.20.20.60 174 330 1.4E-64 T 28-03-2018 CDW54_RS01405 740b6d9f62e2277f18b110e0fdd0d1d2 594 Pfam PF00391 PEP-utilising enzyme, mobile domain 513 584 2.4E-19 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CDW54_RS01405 740b6d9f62e2277f18b110e0fdd0d1d2 594 Gene3D G3DSA:3.20.20.60 1 81 7.5E-16 T 28-03-2018 CDW54_RS01405 740b6d9f62e2277f18b110e0fdd0d1d2 594 SUPERFAMILY SSF50800 87 176 6.63E-22 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain CDW54_RS01405 740b6d9f62e2277f18b110e0fdd0d1d2 594 Gene3D G3DSA:2.40.33.10 82 173 5.1E-22 T 28-03-2018 CDW54_RS01405 740b6d9f62e2277f18b110e0fdd0d1d2 594 SUPERFAMILY SSF51621 165 348 6.28E-99 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CDW54_RS01405 740b6d9f62e2277f18b110e0fdd0d1d2 594 SUPERFAMILY SSF51621 1 74 6.28E-99 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CDW54_RS01405 740b6d9f62e2277f18b110e0fdd0d1d2 594 Gene3D G3DSA:3.40.1380.20 331 482 3.2E-53 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CDW54_RS01405 740b6d9f62e2277f18b110e0fdd0d1d2 594 Gene3D G3DSA:3.50.30.10 483 594 8.6E-25 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CDW54_RS01405 740b6d9f62e2277f18b110e0fdd0d1d2 594 Pfam PF02887 Pyruvate kinase, alpha/beta domain 366 478 2.4E-35 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CDW54_RS01405 740b6d9f62e2277f18b110e0fdd0d1d2 594 PRINTS PR01050 Pyruvate kinase family signature 322 338 3.3E-74 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CDW54_RS01405 740b6d9f62e2277f18b110e0fdd0d1d2 594 PRINTS PR01050 Pyruvate kinase family signature 226 252 3.3E-74 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CDW54_RS01405 740b6d9f62e2277f18b110e0fdd0d1d2 594 PRINTS PR01050 Pyruvate kinase family signature 59 75 3.3E-74 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CDW54_RS01405 740b6d9f62e2277f18b110e0fdd0d1d2 594 PRINTS PR01050 Pyruvate kinase family signature 303 321 3.3E-74 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CDW54_RS01405 740b6d9f62e2277f18b110e0fdd0d1d2 594 PRINTS PR01050 Pyruvate kinase family signature 195 209 3.3E-74 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CDW54_RS01405 740b6d9f62e2277f18b110e0fdd0d1d2 594 PRINTS PR01050 Pyruvate kinase family signature 253 277 3.3E-74 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CDW54_RS01405 740b6d9f62e2277f18b110e0fdd0d1d2 594 PRINTS PR01050 Pyruvate kinase family signature 278 302 3.3E-74 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CDW54_RS01405 740b6d9f62e2277f18b110e0fdd0d1d2 594 Pfam PF00224 Pyruvate kinase, barrel domain 1 352 2.2E-149 T 28-03-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CDW54_RS09400 264ce75f0bccb0c105dfe37aad322a14 299 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS09400 264ce75f0bccb0c105dfe37aad322a14 299 Gene3D G3DSA:3.40.50.300 1 266 1.3E-60 T 28-03-2018 CDW54_RS09400 264ce75f0bccb0c105dfe37aad322a14 299 Pfam PF00005 ABC transporter 18 157 8.1E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS09400 264ce75f0bccb0c105dfe37aad322a14 299 Pfam PF13732 Domain of unknown function (DUF4162) 211 291 6.1E-16 T 28-03-2018 IPR025302 Domain of unknown function DUF4162 CDW54_RS09400 264ce75f0bccb0c105dfe37aad322a14 299 SMART SM00382 26 205 3.2E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS09400 264ce75f0bccb0c105dfe37aad322a14 299 SUPERFAMILY SSF52540 1 225 8.38E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS02015 c34b6c1f5fc102377ff6ca6c651e42df 932 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 228 251 3.6E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CDW54_RS02015 c34b6c1f5fc102377ff6ca6c651e42df 932 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 50 61 3.6E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CDW54_RS02015 c34b6c1f5fc102377ff6ca6c651e42df 932 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 390 405 3.6E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CDW54_RS02015 c34b6c1f5fc102377ff6ca6c651e42df 932 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 552 561 3.6E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CDW54_RS02015 c34b6c1f5fc102377ff6ca6c651e42df 932 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 518 531 3.6E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CDW54_RS02015 c34b6c1f5fc102377ff6ca6c651e42df 932 Gene3D G3DSA:3.40.50.620 391 590 2.0E-52 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDW54_RS02015 c34b6c1f5fc102377ff6ca6c651e42df 932 Gene3D G3DSA:1.10.730.10 591 804 6.9E-57 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDW54_RS02015 c34b6c1f5fc102377ff6ca6c651e42df 932 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 57 68 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDW54_RS02015 c34b6c1f5fc102377ff6ca6c651e42df 932 Gene3D G3DSA:3.30.2320.20 805 885 2.6E-23 T 28-03-2018 CDW54_RS02015 c34b6c1f5fc102377ff6ca6c651e42df 932 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 13 832 5.0E-304 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CDW54_RS02015 c34b6c1f5fc102377ff6ca6c651e42df 932 Gene3D G3DSA:3.40.50.620 46 199 4.4E-37 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDW54_RS02015 c34b6c1f5fc102377ff6ca6c651e42df 932 Pfam PF06827 Zinc finger found in FPG and IleRS 887 916 2.1E-7 T 28-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 CDW54_RS02015 c34b6c1f5fc102377ff6ca6c651e42df 932 Gene3D G3DSA:3.90.740.10 200 390 5.8E-70 T 28-03-2018 CDW54_RS02015 c34b6c1f5fc102377ff6ca6c651e42df 932 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 27 632 4.9E-222 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDW54_RS02015 c34b6c1f5fc102377ff6ca6c651e42df 932 SUPERFAMILY SSF52374 1 200 2.01E-151 T 28-03-2018 CDW54_RS02015 c34b6c1f5fc102377ff6ca6c651e42df 932 SUPERFAMILY SSF52374 392 638 2.01E-151 T 28-03-2018 CDW54_RS02015 c34b6c1f5fc102377ff6ca6c651e42df 932 Pfam PF08264 Anticodon-binding domain of tRNA 676 829 6.1E-27 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CDW54_RS02015 c34b6c1f5fc102377ff6ca6c651e42df 932 SUPERFAMILY SSF47323 643 918 2.24E-73 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDW54_RS02015 c34b6c1f5fc102377ff6ca6c651e42df 932 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 1 918 20.53 T 28-03-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 CDW54_RS02015 c34b6c1f5fc102377ff6ca6c651e42df 932 SUPERFAMILY SSF50677 201 392 1.31E-60 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CDW54_RS06185 c34ecd924fae69e79f6624c91ae1cdef 593 Gene3D G3DSA:3.90.76.10 92 275 6.8E-33 T 28-03-2018 CDW54_RS06185 c34ecd924fae69e79f6624c91ae1cdef 593 PIRSF PIRSF002741 4 585 2.2E-65 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CDW54_RS06185 c34ecd924fae69e79f6624c91ae1cdef 593 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 113 507 1.7E-69 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CDW54_RS06185 c34ecd924fae69e79f6624c91ae1cdef 593 SUPERFAMILY SSF53850 72 585 9.59E-97 T 28-03-2018 CDW54_RS06185 c34ecd924fae69e79f6624c91ae1cdef 593 Gene3D G3DSA:3.10.105.10 314 556 3.8E-45 T 28-03-2018 CDW54_RS04050 2812f69d82ceded92237be7fcb6f3656 430 Pfam PF03129 Anticodon binding domain 332 419 4.9E-12 T 28-03-2018 IPR004154 Anticodon-binding CDW54_RS04050 2812f69d82ceded92237be7fcb6f3656 430 SUPERFAMILY SSF52954 329 419 7.7E-23 T 28-03-2018 IPR004154 Anticodon-binding CDW54_RS04050 2812f69d82ceded92237be7fcb6f3656 430 Gene3D G3DSA:3.40.50.800 328 427 6.3E-19 T 28-03-2018 IPR004154 Anticodon-binding CDW54_RS04050 2812f69d82ceded92237be7fcb6f3656 430 Pfam PF13393 Histidyl-tRNA synthetase 8 314 7.9E-42 T 28-03-2018 CDW54_RS04050 2812f69d82ceded92237be7fcb6f3656 430 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 1 421 33.833 T 28-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CDW54_RS04050 2812f69d82ceded92237be7fcb6f3656 430 PIRSF PIRSF001549 1 422 5.0E-119 T 28-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 CDW54_RS04050 2812f69d82ceded92237be7fcb6f3656 430 SUPERFAMILY SSF55681 3 319 1.9E-96 T 28-03-2018 CDW54_RS04050 2812f69d82ceded92237be7fcb6f3656 430 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 4 411 1.0E-156 T 28-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CDW54_RS04050 2812f69d82ceded92237be7fcb6f3656 430 Gene3D G3DSA:3.30.930.10 1 324 3.3E-73 T 28-03-2018 CDW54_RS06660 db738cfc5abf2c80de19c1162e2bf152 391 Gene3D G3DSA:3.40.50.300 1 247 1.3E-78 T 28-03-2018 CDW54_RS06660 db738cfc5abf2c80de19c1162e2bf152 391 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS06660 db738cfc5abf2c80de19c1162e2bf152 391 SMART SM00116 258 306 4.2E-5 T 28-03-2018 IPR000644 CBS domain CDW54_RS06660 db738cfc5abf2c80de19c1162e2bf152 391 SMART SM00116 318 366 1.4E-7 T 28-03-2018 IPR000644 CBS domain CDW54_RS06660 db738cfc5abf2c80de19c1162e2bf152 391 SUPERFAMILY SSF54631 249 372 6.47E-26 T 28-03-2018 CDW54_RS06660 db738cfc5abf2c80de19c1162e2bf152 391 Gene3D G3DSA:3.10.580.10 248 391 5.0E-25 T 28-03-2018 CDW54_RS06660 db738cfc5abf2c80de19c1162e2bf152 391 SUPERFAMILY SSF52540 1 240 2.16E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS06660 db738cfc5abf2c80de19c1162e2bf152 391 Pfam PF00005 ABC transporter 19 163 1.4E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS06660 db738cfc5abf2c80de19c1162e2bf152 391 Pfam PF00571 CBS domain 311 363 4.0E-10 T 28-03-2018 IPR000644 CBS domain CDW54_RS06660 db738cfc5abf2c80de19c1162e2bf152 391 Pfam PF00571 CBS domain 251 298 1.7E-6 T 28-03-2018 IPR000644 CBS domain CDW54_RS06660 db738cfc5abf2c80de19c1162e2bf152 391 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 13 371 1.3E-143 T 28-03-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 CDW54_RS06660 db738cfc5abf2c80de19c1162e2bf152 391 SMART SM00382 27 221 4.9E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS06780 4fe206889c3c98238967f113bac1425b 709 Gene3D G3DSA:3.30.420.40 2 105 1.1E-12 T 28-03-2018 CDW54_RS06780 4fe206889c3c98238967f113bac1425b 709 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 6 173 4.2E-17 T 28-03-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403 CDW54_RS06780 4fe206889c3c98238967f113bac1425b 709 Gene3D G3DSA:3.30.420.150 254 533 3.7E-11 T 28-03-2018 CDW54_RS06780 4fe206889c3c98238967f113bac1425b 709 Pfam PF01968 Hydantoinase/oxoprolinase 195 501 1.5E-63 T 28-03-2018 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Reactome: R-HSA-174403 CDW54_RS06780 4fe206889c3c98238967f113bac1425b 709 SUPERFAMILY SSF53067 253 360 2.93E-16 T 28-03-2018 CDW54_RS06780 4fe206889c3c98238967f113bac1425b 709 SUPERFAMILY SSF53067 7 86 2.93E-16 T 28-03-2018 CDW54_RS06780 4fe206889c3c98238967f113bac1425b 709 SUPERFAMILY SSF53067 401 497 2.93E-16 T 28-03-2018 CDW54_RS09490 4f0bb135b4581c4d5f6ffede067e6d82 260 PIRSF PIRSF016184 1 260 1.6E-67 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CDW54_RS09490 4f0bb135b4581c4d5f6ffede067e6d82 260 Pfam PF02567 Phenazine biosynthesis-like protein 8 256 1.7E-61 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CDW54_RS09490 4f0bb135b4581c4d5f6ffede067e6d82 260 Gene3D G3DSA:3.10.310.10 121 248 1.3E-33 T 28-03-2018 CDW54_RS09490 4f0bb135b4581c4d5f6ffede067e6d82 260 Gene3D G3DSA:3.10.310.10 1 120 3.4E-31 T 28-03-2018 CDW54_RS09490 4f0bb135b4581c4d5f6ffede067e6d82 260 SUPERFAMILY SSF54506 1 259 4.89E-83 T 28-03-2018 CDW54_RS09490 4f0bb135b4581c4d5f6ffede067e6d82 260 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 1 240 3.5E-38 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CDW54_RS02245 db7b1b3d1243631a28727ea309182d9d 334 SUPERFAMILY SSF82649 248 334 8.37E-27 T 28-03-2018 CDW54_RS02245 db7b1b3d1243631a28727ea309182d9d 334 TIGRFAM TIGR00545 lipoyltrans: lipoyltransferase and lipoate-protein ligase 6 327 3.9E-122 T 28-03-2018 IPR004562 Lipoyltransferase/lipoate-protein ligase GO:0009249 KEGG: 00785+6.3.1.20|Reactome: R-HSA-389661 CDW54_RS02245 db7b1b3d1243631a28727ea309182d9d 334 SUPERFAMILY SSF55681 1 246 1.35E-81 T 28-03-2018 CDW54_RS02245 db7b1b3d1243631a28727ea309182d9d 334 Gene3D G3DSA:3.30.930.10 1 249 1.1E-69 T 28-03-2018 CDW54_RS02245 db7b1b3d1243631a28727ea309182d9d 334 Gene3D G3DSA:3.30.390.50 250 334 2.5E-27 T 28-03-2018 CDW54_RS02245 db7b1b3d1243631a28727ea309182d9d 334 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 249 333 1.5E-31 T 28-03-2018 IPR019491 Lipoate protein ligase, C-terminal KEGG: 00785+6.3.1.20 CDW54_RS02245 db7b1b3d1243631a28727ea309182d9d 334 Pfam PF03099 Biotin/lipoate A/B protein ligase family 46 153 4.7E-12 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CDW54_RS01605 aeffa56796eaaf19d3ff23e7d9ccb325 575 Gene3D G3DSA:3.20.20.60 257 575 1.5E-100 T 28-03-2018 CDW54_RS01605 aeffa56796eaaf19d3ff23e7d9ccb325 575 Pfam PF05524 PEP-utilising enzyme, N-terminal 6 128 5.7E-33 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CDW54_RS01605 aeffa56796eaaf19d3ff23e7d9ccb325 575 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 504 516 7.5E-32 T 28-03-2018 CDW54_RS01605 aeffa56796eaaf19d3ff23e7d9ccb325 575 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 295 314 7.5E-32 T 28-03-2018 CDW54_RS01605 aeffa56796eaaf19d3ff23e7d9ccb325 575 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 451 466 7.5E-32 T 28-03-2018 CDW54_RS01605 aeffa56796eaaf19d3ff23e7d9ccb325 575 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 468 483 7.5E-32 T 28-03-2018 CDW54_RS01605 aeffa56796eaaf19d3ff23e7d9ccb325 575 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 5 570 9.6E-234 T 28-03-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 CDW54_RS01605 aeffa56796eaaf19d3ff23e7d9ccb325 575 SUPERFAMILY SSF52009 127 243 8.63E-37 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CDW54_RS01605 aeffa56796eaaf19d3ff23e7d9ccb325 575 Gene3D G3DSA:3.50.30.10 137 256 5.3E-30 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CDW54_RS01605 aeffa56796eaaf19d3ff23e7d9ccb325 575 Pfam PF00391 PEP-utilising enzyme, mobile domain 155 227 7.3E-24 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CDW54_RS01605 aeffa56796eaaf19d3ff23e7d9ccb325 575 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 451 469 - T 28-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 CDW54_RS01605 aeffa56796eaaf19d3ff23e7d9ccb325 575 Gene3D G3DSA:1.10.274.10 26 136 1.1E-37 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CDW54_RS01605 aeffa56796eaaf19d3ff23e7d9ccb325 575 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 186 197 - T 28-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 CDW54_RS01605 aeffa56796eaaf19d3ff23e7d9ccb325 575 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 252 545 7.2E-126 T 28-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 CDW54_RS01605 aeffa56796eaaf19d3ff23e7d9ccb325 575 SUPERFAMILY SSF51621 251 553 1.6E-109 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CDW54_RS01605 aeffa56796eaaf19d3ff23e7d9ccb325 575 PIRSF PIRSF000732 1 575 6.4E-216 T 28-03-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 CDW54_RS01605 aeffa56796eaaf19d3ff23e7d9ccb325 575 SUPERFAMILY SSF47831 24 145 5.75E-36 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CDW54_RS07165 4a770843ab54ce7c6508fa4550257962 611 ProSitePatterns PS00392 DDC / GAD / HDC / TyrDC pyridoxal-phosphate attachment site. 378 399 - T 28-03-2018 IPR021115 Pyridoxal-phosphate binding site GO:0016831 CDW54_RS07165 4a770843ab54ce7c6508fa4550257962 611 Gene3D G3DSA:3.40.640.10 99 439 3.2E-39 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDW54_RS07165 4a770843ab54ce7c6508fa4550257962 611 Gene3D G3DSA:3.90.1150.10 440 604 1.7E-6 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDW54_RS07165 4a770843ab54ce7c6508fa4550257962 611 TIGRFAM TIGR03811 tyr_de_CO2_Ent: tyrosine decarboxylase 3 609 1.4E-298 T 28-03-2018 IPR022397 Tyrosine decarboxylase, bacteria CDW54_RS07165 4a770843ab54ce7c6508fa4550257962 611 SUPERFAMILY SSF53383 370 548 2.82E-74 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDW54_RS07165 4a770843ab54ce7c6508fa4550257962 611 SUPERFAMILY SSF53383 214 330 2.82E-74 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDW54_RS07165 4a770843ab54ce7c6508fa4550257962 611 SUPERFAMILY SSF53383 19 166 2.82E-74 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDW54_RS07165 4a770843ab54ce7c6508fa4550257962 611 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 232 328 2.0E-14 T 28-03-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 CDW54_RS07165 4a770843ab54ce7c6508fa4550257962 611 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 364 475 7.9E-6 T 28-03-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 CDW54_RS09560 e7e98c96a4feed667dd2fcfa39effb23 345 Gene3D G3DSA:3.40.50.1360 95 345 1.6E-37 T 28-03-2018 CDW54_RS09560 e7e98c96a4feed667dd2fcfa39effb23 345 SUPERFAMILY SSF46785 20 84 3.84E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS09560 e7e98c96a4feed667dd2fcfa39effb23 345 Pfam PF04198 Putative sugar-binding domain 91 341 2.4E-62 T 28-03-2018 IPR007324 Sugar-binding domain, putative GO:0030246 CDW54_RS09560 e7e98c96a4feed667dd2fcfa39effb23 345 Gene3D G3DSA:1.10.10.10 17 87 4.0E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS09560 e7e98c96a4feed667dd2fcfa39effb23 345 SUPERFAMILY SSF100950 96 341 1.26E-66 T 28-03-2018 CDW54_RS10590 96d4d94d3637c2badc915a24ca5fae79 448 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 408 425 - T 28-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDW54_RS10590 96d4d94d3637c2badc915a24ca5fae79 448 Gene3D G3DSA:3.40.50.10490 62 207 8.9E-44 T 28-03-2018 CDW54_RS10590 96d4d94d3637c2badc915a24ca5fae79 448 PRINTS PR00662 Glucose-6-phosphate isomerase signature 198 216 5.0E-26 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDW54_RS10590 96d4d94d3637c2badc915a24ca5fae79 448 PRINTS PR00662 Glucose-6-phosphate isomerase signature 394 408 5.0E-26 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDW54_RS10590 96d4d94d3637c2badc915a24ca5fae79 448 PRINTS PR00662 Glucose-6-phosphate isomerase signature 376 394 5.0E-26 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDW54_RS10590 96d4d94d3637c2badc915a24ca5fae79 448 PRINTS PR00662 Glucose-6-phosphate isomerase signature 76 95 5.0E-26 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDW54_RS10590 96d4d94d3637c2badc915a24ca5fae79 448 PRINTS PR00662 Glucose-6-phosphate isomerase signature 408 421 5.0E-26 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDW54_RS10590 96d4d94d3637c2badc915a24ca5fae79 448 PRINTS PR00662 Glucose-6-phosphate isomerase signature 273 294 5.0E-26 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDW54_RS10590 96d4d94d3637c2badc915a24ca5fae79 448 Gene3D G3DSA:3.40.50.10490 1 61 2.6E-11 T 28-03-2018 CDW54_RS10590 96d4d94d3637c2badc915a24ca5fae79 448 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 202 215 - T 28-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDW54_RS10590 96d4d94d3637c2badc915a24ca5fae79 448 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 1 435 25.1 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDW54_RS10590 96d4d94d3637c2badc915a24ca5fae79 448 Gene3D G3DSA:3.40.50.10490 208 434 2.4E-73 T 28-03-2018 CDW54_RS10590 96d4d94d3637c2badc915a24ca5fae79 448 Pfam PF00342 Phosphoglucose isomerase 76 296 1.9E-18 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDW54_RS10590 96d4d94d3637c2badc915a24ca5fae79 448 SUPERFAMILY SSF53697 5 447 8.9E-140 T 28-03-2018 CDW54_RS07510 eaf8af117bb8d6d87d472add7ad2e1f8 199 SUPERFAMILY SSF46689 4 87 3.54E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDW54_RS07510 eaf8af117bb8d6d87d472add7ad2e1f8 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 5.3E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDW54_RS07510 eaf8af117bb8d6d87d472add7ad2e1f8 199 Gene3D G3DSA:1.10.357.10 64 194 3.7E-8 T 28-03-2018 CDW54_RS07510 eaf8af117bb8d6d87d472add7ad2e1f8 199 Gene3D G3DSA:1.10.10.60 5 63 6.9E-15 T 28-03-2018 CDW54_RS03305 2decfa93742bbfa438fa0af8e5c4c311 99 Pfam PF08951 Enterocin A Immunity 8 75 7.4E-17 T 28-03-2018 IPR015046 Enterocin A Immunity CDW54_RS03305 2decfa93742bbfa438fa0af8e5c4c311 99 Gene3D G3DSA:1.20.1440.50 4 86 4.8E-12 T 28-03-2018 IPR023130 Ta0600-like domain CDW54_RS00495 4481fe30d1d8d615124b466eeeb18984 274 SUPERFAMILY SSF55166 105 259 1.6E-29 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CDW54_RS00495 4481fe30d1d8d615124b466eeeb18984 274 Gene3D G3DSA:3.30.1380.10 73 263 7.2E-35 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CDW54_RS00495 4481fe30d1d8d615124b466eeeb18984 274 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 109 251 9.3E-38 T 28-03-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 CDW54_RS03585 00230ad3b9a571dc8e6c4f5ceb077199 423 Gene3D G3DSA:3.40.190.10 36 218 7.4E-43 T 28-03-2018 CDW54_RS03585 00230ad3b9a571dc8e6c4f5ceb077199 423 SUPERFAMILY SSF53850 21 421 4.67E-80 T 28-03-2018 CDW54_RS03585 00230ad3b9a571dc8e6c4f5ceb077199 423 Pfam PF13416 Bacterial extracellular solute-binding protein 54 364 4.3E-43 T 28-03-2018 CDW54_RS03585 00230ad3b9a571dc8e6c4f5ceb077199 423 Gene3D G3DSA:3.40.190.10 219 378 6.2E-11 T 28-03-2018 CDW54_RS08035 e738774acdd757235adee6a51a9adeb9 545 Gene3D G3DSA:3.40.449.10 75 232 7.1E-30 T 28-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CDW54_RS08035 e738774acdd757235adee6a51a9adeb9 545 SUPERFAMILY SSF68923 53 230 1.71E-27 T 28-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CDW54_RS08035 e738774acdd757235adee6a51a9adeb9 545 Pfam PF01293 Phosphoenolpyruvate carboxykinase 100 477 3.7E-21 T 28-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 CDW54_RS08035 e738774acdd757235adee6a51a9adeb9 545 SUPERFAMILY SSF53795 234 538 2.52E-56 T 28-03-2018 CDW54_RS08035 e738774acdd757235adee6a51a9adeb9 545 Gene3D G3DSA:3.90.228.20 234 326 3.3E-11 T 28-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CDW54_RS08035 e738774acdd757235adee6a51a9adeb9 545 Gene3D G3DSA:3.90.228.20 327 506 3.5E-33 T 28-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CDW54_RS09215 46cd0c5841d581a6d584de525b806689 218 SUPERFAMILY SSF51735 82 205 4.33E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS09215 46cd0c5841d581a6d584de525b806689 218 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 1 209 40.031 T 28-03-2018 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 CDW54_RS09215 46cd0c5841d581a6d584de525b806689 218 Gene3D G3DSA:1.10.10.10 4 70 2.9E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS09215 46cd0c5841d581a6d584de525b806689 218 SUPERFAMILY SSF46785 7 78 4.63E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS09215 46cd0c5841d581a6d584de525b806689 218 Gene3D G3DSA:3.40.50.720 71 186 5.1E-21 T 28-03-2018 CDW54_RS09215 46cd0c5841d581a6d584de525b806689 218 Pfam PF06971 Putative DNA-binding protein N-terminus 6 53 1.3E-19 T 28-03-2018 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 CDW54_RS09215 46cd0c5841d581a6d584de525b806689 218 SMART SM00881 79 180 3.9E-22 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CDW54_RS09215 46cd0c5841d581a6d584de525b806689 218 Pfam PF02629 CoA binding domain 81 178 7.9E-28 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CDW54_RS09265 553616c263e849c18004a3ac5c8d3a4d 143 Gene3D G3DSA:3.30.420.140 1 142 9.1E-44 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CDW54_RS09265 553616c263e849c18004a3ac5c8d3a4d 143 SUPERFAMILY SSF53098 1 137 4.4E-42 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS09265 553616c263e849c18004a3ac5c8d3a4d 143 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 1 139 26.786 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CDW54_RS09265 553616c263e849c18004a3ac5c8d3a4d 143 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 4 136 1.2E-44 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CDW54_RS09265 553616c263e849c18004a3ac5c8d3a4d 143 SMART SM00732 1 103 2.6E-39 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CDW54_RS09265 553616c263e849c18004a3ac5c8d3a4d 143 Pfam PF03652 Holliday junction resolvase 1 136 2.6E-42 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CDW54_RS06585 8853cc8deae6dfdd549c2b36112d50fa 373 SMART SM01005 247 372 9.5E-66 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CDW54_RS06585 8853cc8deae6dfdd549c2b36112d50fa 373 SUPERFAMILY SSF51419 13 248 1.89E-63 T 28-03-2018 IPR029066 PLP-binding barrel CDW54_RS06585 8853cc8deae6dfdd549c2b36112d50fa 373 TIGRFAM TIGR00492 alr: alanine racemase 8 371 6.9E-110 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CDW54_RS06585 8853cc8deae6dfdd549c2b36112d50fa 373 SUPERFAMILY SSF50621 242 372 1.53E-48 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CDW54_RS06585 8853cc8deae6dfdd549c2b36112d50fa 373 Pfam PF01168 Alanine racemase, N-terminal domain 13 233 4.9E-64 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CDW54_RS06585 8853cc8deae6dfdd549c2b36112d50fa 373 Pfam PF00842 Alanine racemase, C-terminal domain 247 371 3.2E-43 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CDW54_RS06585 8853cc8deae6dfdd549c2b36112d50fa 373 Hamap MF_01201 Alanine racemase. 6 372 33.676 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CDW54_RS06585 8853cc8deae6dfdd549c2b36112d50fa 373 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 37 47 - T 28-03-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CDW54_RS06585 8853cc8deae6dfdd549c2b36112d50fa 373 Gene3D G3DSA:3.20.20.10 1 231 1.0E-43 T 28-03-2018 IPR029066 PLP-binding barrel CDW54_RS06585 8853cc8deae6dfdd549c2b36112d50fa 373 Gene3D G3DSA:2.40.37.10 232 373 8.5E-55 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CDW54_RS06585 8853cc8deae6dfdd549c2b36112d50fa 373 PRINTS PR00992 Alanine racemase signature 166 177 4.7E-66 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CDW54_RS06585 8853cc8deae6dfdd549c2b36112d50fa 373 PRINTS PR00992 Alanine racemase signature 263 278 4.7E-66 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CDW54_RS06585 8853cc8deae6dfdd549c2b36112d50fa 373 PRINTS PR00992 Alanine racemase signature 300 317 4.7E-66 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CDW54_RS06585 8853cc8deae6dfdd549c2b36112d50fa 373 PRINTS PR00992 Alanine racemase signature 131 143 4.7E-66 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CDW54_RS06585 8853cc8deae6dfdd549c2b36112d50fa 373 PRINTS PR00992 Alanine racemase signature 354 367 4.7E-66 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CDW54_RS06585 8853cc8deae6dfdd549c2b36112d50fa 373 PRINTS PR00992 Alanine racemase signature 32 48 4.7E-66 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CDW54_RS06585 8853cc8deae6dfdd549c2b36112d50fa 373 PRINTS PR00992 Alanine racemase signature 206 233 4.7E-66 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CDW54_RS06585 8853cc8deae6dfdd549c2b36112d50fa 373 PRINTS PR00992 Alanine racemase signature 68 86 4.7E-66 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CDW54_RS06585 8853cc8deae6dfdd549c2b36112d50fa 373 PRINTS PR00992 Alanine racemase signature 280 295 4.7E-66 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CDW54_RS09580 b11bd84d2bfdf4c8ee79ffd6984d2ec0 432 SMART SM01193 4 134 1.2E-97 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CDW54_RS09580 b11bd84d2bfdf4c8ee79ffd6984d2ec0 432 ProSitePatterns PS00164 Enolase signature. 337 350 - T 28-03-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDW54_RS09580 b11bd84d2bfdf4c8ee79ffd6984d2ec0 432 SUPERFAMILY SSF54826 3 138 1.77E-59 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CDW54_RS09580 b11bd84d2bfdf4c8ee79ffd6984d2ec0 432 Gene3D G3DSA:3.20.20.120 128 432 1.7E-106 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CDW54_RS09580 b11bd84d2bfdf4c8ee79ffd6984d2ec0 432 SMART SM01192 139 428 9.2E-226 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CDW54_RS09580 b11bd84d2bfdf4c8ee79ffd6984d2ec0 432 PIRSF PIRSF001400 1 428 1.4E-197 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CDW54_RS09580 b11bd84d2bfdf4c8ee79ffd6984d2ec0 432 SUPERFAMILY SSF51604 139 429 2.97E-132 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CDW54_RS09580 b11bd84d2bfdf4c8ee79ffd6984d2ec0 432 PRINTS PR00148 Enolase signature 366 383 1.1E-46 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CDW54_RS09580 b11bd84d2bfdf4c8ee79ffd6984d2ec0 432 PRINTS PR00148 Enolase signature 314 325 1.1E-46 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CDW54_RS09580 b11bd84d2bfdf4c8ee79ffd6984d2ec0 432 PRINTS PR00148 Enolase signature 107 123 1.1E-46 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CDW54_RS09580 b11bd84d2bfdf4c8ee79ffd6984d2ec0 432 PRINTS PR00148 Enolase signature 337 351 1.1E-46 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CDW54_RS09580 b11bd84d2bfdf4c8ee79ffd6984d2ec0 432 PRINTS PR00148 Enolase signature 161 174 1.1E-46 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CDW54_RS09580 b11bd84d2bfdf4c8ee79ffd6984d2ec0 432 PRINTS PR00148 Enolase signature 37 51 1.1E-46 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CDW54_RS09580 b11bd84d2bfdf4c8ee79ffd6984d2ec0 432 Pfam PF03952 Enolase, N-terminal domain 4 134 2.5E-62 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CDW54_RS09580 b11bd84d2bfdf4c8ee79ffd6984d2ec0 432 Hamap MF_00318 Enolase [eno]. 2 414 46.152 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CDW54_RS09580 b11bd84d2bfdf4c8ee79ffd6984d2ec0 432 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 426 5.5E-139 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CDW54_RS09580 b11bd84d2bfdf4c8ee79ffd6984d2ec0 432 Gene3D G3DSA:3.30.390.10 3 127 2.9E-55 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CDW54_RS09580 b11bd84d2bfdf4c8ee79ffd6984d2ec0 432 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 428 2.0E-218 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CDW54_RS09235 9bc54a55345c4940046ef60448ce03a2 258 SUPERFAMILY SSF52172 4 129 9.68E-10 T 28-03-2018 IPR011006 CheY-like superfamily CDW54_RS09235 9bc54a55345c4940046ef60448ce03a2 258 Pfam PF04397 LytTr DNA-binding domain 156 249 6.0E-10 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CDW54_RS09235 9bc54a55345c4940046ef60448ce03a2 258 Gene3D G3DSA:3.40.50.2300 2 142 1.1E-12 T 28-03-2018 CDW54_RS09235 9bc54a55345c4940046ef60448ce03a2 258 Gene3D G3DSA:2.40.50.40 143 216 2.2E-6 T 28-03-2018 CDW54_RS09235 9bc54a55345c4940046ef60448ce03a2 258 Pfam PF00072 Response regulator receiver domain 5 123 2.0E-8 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDW54_RS09235 9bc54a55345c4940046ef60448ce03a2 258 SMART SM00850 153 250 0.0021 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CDW54_RS02335 18083ce476c609790a808f058f42d5ed 312 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 15 196 9.3E-68 T 28-03-2018 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDW54_RS02335 18083ce476c609790a808f058f42d5ed 312 Gene3D G3DSA:1.10.8.60 157 202 1.0E-6 T 28-03-2018 CDW54_RS02335 18083ce476c609790a808f058f42d5ed 312 SUPERFAMILY SSF52540 10 193 5.78E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS02335 18083ce476c609790a808f058f42d5ed 312 Pfam PF13177 DNA polymerase III, delta subunit 11 169 8.7E-61 T 28-03-2018 CDW54_RS02335 18083ce476c609790a808f058f42d5ed 312 Gene3D G3DSA:3.40.50.300 10 156 8.7E-30 T 28-03-2018 CDW54_RS08945 dd894d00d4b9f5717d8c2f238dcc4bc5 660 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 24 41 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CDW54_RS08945 dd894d00d4b9f5717d8c2f238dcc4bc5 660 Pfam PF00367 phosphotransferase system, EIIB 13 46 7.5E-9 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CDW54_RS08945 dd894d00d4b9f5717d8c2f238dcc4bc5 660 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 514 637 2.1E-43 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CDW54_RS08945 dd894d00d4b9f5717d8c2f238dcc4bc5 660 Gene3D G3DSA:1.20.1250.20 116 502 9.5E-4 T 28-03-2018 CDW54_RS08945 dd894d00d4b9f5717d8c2f238dcc4bc5 660 SUPERFAMILY SSF55604 10 86 7.72E-17 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CDW54_RS08945 dd894d00d4b9f5717d8c2f238dcc4bc5 660 Gene3D G3DSA:2.70.70.10 503 660 3.9E-51 T 28-03-2018 CDW54_RS08945 dd894d00d4b9f5717d8c2f238dcc4bc5 660 SUPERFAMILY SSF51261 509 655 7.32E-46 T 28-03-2018 IPR011055 Duplicated hybrid motif CDW54_RS08945 dd894d00d4b9f5717d8c2f238dcc4bc5 660 Pfam PF02378 Phosphotransferase system, EIIC 139 421 3.0E-34 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CDW54_RS08945 dd894d00d4b9f5717d8c2f238dcc4bc5 660 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 516 634 1.8E-34 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CDW54_RS08945 dd894d00d4b9f5717d8c2f238dcc4bc5 660 Gene3D G3DSA:3.30.1360.60 9 85 3.0E-22 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CDW54_RS08945 dd894d00d4b9f5717d8c2f238dcc4bc5 660 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 576 588 - T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CDW54_RS04005 943c5dd970774e2977b992a7ae993de0 1064 Pfam PF04434 SWIM zinc finger 57 78 8.8E-4 T 28-03-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 CDW54_RS04005 943c5dd970774e2977b992a7ae993de0 1064 Pfam PF08455 Bacterial SNF2 helicase associated 231 605 1.4E-76 T 28-03-2018 IPR013663 Helicase, SWF/SNF/SWI type, bacterial CDW54_RS04005 943c5dd970774e2977b992a7ae993de0 1064 SUPERFAMILY SSF52540 596 810 3.46E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS04005 943c5dd970774e2977b992a7ae993de0 1064 Pfam PF00271 Helicase conserved C-terminal domain 892 1003 4.3E-21 T 28-03-2018 IPR001650 Helicase, C-terminal CDW54_RS04005 943c5dd970774e2977b992a7ae993de0 1064 Gene3D G3DSA:3.40.50.300 882 1041 2.7E-40 T 28-03-2018 CDW54_RS04005 943c5dd970774e2977b992a7ae993de0 1064 SUPERFAMILY SSF52540 812 1059 1.9E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS04005 943c5dd970774e2977b992a7ae993de0 1064 Gene3D G3DSA:3.40.50.10810 582 805 4.9E-51 T 28-03-2018 CDW54_RS04005 943c5dd970774e2977b992a7ae993de0 1064 Pfam PF00176 SNF2 family N-terminal domain 627 881 2.1E-56 T 28-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 CDW54_RS04005 943c5dd970774e2977b992a7ae993de0 1064 SMART SM00490 921 1003 2.4E-26 T 28-03-2018 IPR001650 Helicase, C-terminal CDW54_RS04005 943c5dd970774e2977b992a7ae993de0 1064 SMART SM00487 608 794 1.4E-36 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CDW54_RS02490 f9abbba008a1fa6b948e9b99300558b2 409 Gene3D G3DSA:3.40.50.300 162 227 3.9E-11 T 28-03-2018 CDW54_RS02490 f9abbba008a1fa6b948e9b99300558b2 409 PIRSF PIRSF006809 1 409 4.1E-144 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 CDW54_RS02490 f9abbba008a1fa6b948e9b99300558b2 409 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 263 281 4.9E-8 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CDW54_RS02490 f9abbba008a1fa6b948e9b99300558b2 409 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 196 216 4.9E-8 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CDW54_RS02490 f9abbba008a1fa6b948e9b99300558b2 409 SUPERFAMILY SSF52540 194 380 1.41E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS02490 f9abbba008a1fa6b948e9b99300558b2 409 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 4 352 9.6E-139 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 CDW54_RS02490 f9abbba008a1fa6b948e9b99300558b2 409 Pfam PF16360 GTP-binding GTPase Middle Region 110 188 1.8E-32 T 28-03-2018 IPR032305 GTP-binding protein, middle domain CDW54_RS02490 f9abbba008a1fa6b948e9b99300558b2 409 Hamap MF_00900 GTPase HflX [hflX]. 23 381 42.92 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 CDW54_RS02490 f9abbba008a1fa6b948e9b99300558b2 409 Gene3D G3DSA:3.40.50.300 228 376 3.7E-15 T 28-03-2018 CDW54_RS02490 f9abbba008a1fa6b948e9b99300558b2 409 Pfam PF01926 50S ribosome-binding GTPase 195 314 8.5E-19 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CDW54_RS02490 f9abbba008a1fa6b948e9b99300558b2 409 Pfam PF13167 GTP-binding GTPase N-terminal 21 108 1.0E-29 T 28-03-2018 IPR025121 GTPase HflX, N-terminal CDW54_RS07930 4bc9d299dd53bfc4e2562a580d6df1b7 453 PIRSF PIRSF000726 3 445 2.8E-69 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CDW54_RS07930 4bc9d299dd53bfc4e2562a580d6df1b7 453 SUPERFAMILY SSF55021 287 381 1.26E-14 T 28-03-2018 CDW54_RS07930 4bc9d299dd53bfc4e2562a580d6df1b7 453 SUPERFAMILY SSF55021 362 438 7.2E-9 T 28-03-2018 CDW54_RS07930 4bc9d299dd53bfc4e2562a580d6df1b7 453 Gene3D G3DSA:3.30.70.260 362 445 2.4E-7 T 28-03-2018 CDW54_RS07930 4bc9d299dd53bfc4e2562a580d6df1b7 453 SUPERFAMILY SSF53633 6 280 6.68E-58 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CDW54_RS07930 4bc9d299dd53bfc4e2562a580d6df1b7 453 Gene3D G3DSA:3.30.70.260 275 361 1.7E-16 T 28-03-2018 CDW54_RS07930 4bc9d299dd53bfc4e2562a580d6df1b7 453 ProSitePatterns PS00324 Aspartokinase signature. 7 15 - T 28-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CDW54_RS07930 4bc9d299dd53bfc4e2562a580d6df1b7 453 Pfam PF00696 Amino acid kinase family 6 267 1.3E-43 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CDW54_RS07930 4bc9d299dd53bfc4e2562a580d6df1b7 453 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 7 436 4.4E-71 T 28-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CDW54_RS07930 4bc9d299dd53bfc4e2562a580d6df1b7 453 Gene3D G3DSA:3.40.1160.10 5 274 1.9E-46 T 28-03-2018 CDW54_RS04905 30ace3bcf05ea5b88cab72c6b75d2431 163 Pfam PF01327 Polypeptide deformylase 4 146 1.0E-47 T 28-03-2018 IPR023635 Peptide deformylase CDW54_RS04905 30ace3bcf05ea5b88cab72c6b75d2431 163 Hamap MF_00163 Peptide deformylase [def]. 1 159 28.046 T 28-03-2018 IPR023635 Peptide deformylase CDW54_RS04905 30ace3bcf05ea5b88cab72c6b75d2431 163 PIRSF PIRSF004749 1 163 1.5E-48 T 28-03-2018 IPR023635 Peptide deformylase CDW54_RS04905 30ace3bcf05ea5b88cab72c6b75d2431 163 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 5 157 1.2E-48 T 28-03-2018 IPR023635 Peptide deformylase CDW54_RS04905 30ace3bcf05ea5b88cab72c6b75d2431 163 PRINTS PR01576 Peptide deformylase signature 98 116 5.3E-36 T 28-03-2018 IPR023635 Peptide deformylase CDW54_RS04905 30ace3bcf05ea5b88cab72c6b75d2431 163 PRINTS PR01576 Peptide deformylase signature 117 146 5.3E-36 T 28-03-2018 IPR023635 Peptide deformylase CDW54_RS04905 30ace3bcf05ea5b88cab72c6b75d2431 163 PRINTS PR01576 Peptide deformylase signature 86 97 5.3E-36 T 28-03-2018 IPR023635 Peptide deformylase CDW54_RS04905 30ace3bcf05ea5b88cab72c6b75d2431 163 PRINTS PR01576 Peptide deformylase signature 32 61 5.3E-36 T 28-03-2018 IPR023635 Peptide deformylase CDW54_RS04905 30ace3bcf05ea5b88cab72c6b75d2431 163 Gene3D G3DSA:3.90.45.10 2 162 9.6E-54 T 28-03-2018 IPR023635 Peptide deformylase CDW54_RS04905 30ace3bcf05ea5b88cab72c6b75d2431 163 SUPERFAMILY SSF56420 1 158 7.85E-55 T 28-03-2018 IPR023635 Peptide deformylase CDW54_RS04900 4322ea304a0655b9f59004b04eb6ac65 312 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 3 305 1.2E-100 T 28-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 CDW54_RS04900 4322ea304a0655b9f59004b04eb6ac65 312 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 133 156 - T 28-03-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CDW54_RS04900 4322ea304a0655b9f59004b04eb6ac65 312 SUPERFAMILY SSF53328 3 202 1.07E-64 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CDW54_RS04900 4322ea304a0655b9f59004b04eb6ac65 312 Gene3D G3DSA:3.10.25.10 206 311 1.4E-31 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CDW54_RS04900 4322ea304a0655b9f59004b04eb6ac65 312 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 2 304 35.101 T 28-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 CDW54_RS04900 4322ea304a0655b9f59004b04eb6ac65 312 Gene3D G3DSA:3.40.50.170 1 205 7.8E-66 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CDW54_RS04900 4322ea304a0655b9f59004b04eb6ac65 312 SUPERFAMILY SSF50486 204 306 4.24E-31 T 28-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 CDW54_RS04900 4322ea304a0655b9f59004b04eb6ac65 312 Pfam PF00551 Formyl transferase 3 180 2.4E-37 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CDW54_RS04900 4322ea304a0655b9f59004b04eb6ac65 312 Pfam PF02911 Formyl transferase, C-terminal domain 203 301 1.2E-28 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CDW54_RS00990 e6a3d3e3725e167d349bb8a5f5f80003 295 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 5 87 2.8E-23 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CDW54_RS00990 e6a3d3e3725e167d349bb8a5f5f80003 295 Pfam PF00589 Phage integrase family 111 281 4.1E-54 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CDW54_RS00990 e6a3d3e3725e167d349bb8a5f5f80003 295 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 3 295 57.613 T 28-03-2018 IPR023009 Tyrosine recombinase XerC/XerD CDW54_RS00990 e6a3d3e3725e167d349bb8a5f5f80003 295 Gene3D G3DSA:1.10.150.130 1 109 6.2E-27 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CDW54_RS00990 e6a3d3e3725e167d349bb8a5f5f80003 295 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 7 295 7.0E-122 T 28-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 CDW54_RS00990 e6a3d3e3725e167d349bb8a5f5f80003 295 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 7 295 1.1E-101 T 28-03-2018 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007049|GO:0007059|GO:0015074|GO:0051301 CDW54_RS00990 e6a3d3e3725e167d349bb8a5f5f80003 295 Gene3D G3DSA:1.10.443.10 110 289 2.2E-52 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CDW54_RS00990 e6a3d3e3725e167d349bb8a5f5f80003 295 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 1 295 59.019 T 28-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 CDW54_RS00990 e6a3d3e3725e167d349bb8a5f5f80003 295 SUPERFAMILY SSF56349 3 286 1.24E-61 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CDW54_RS09940 2b4830e3774b8f4975eb63f93bee1a61 467 SUPERFAMILY SSF51735 4 168 8.02E-54 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS09940 2b4830e3774b8f4975eb63f93bee1a61 467 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 197 411 9.3E-49 T 28-03-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 CDW54_RS09940 2b4830e3774b8f4975eb63f93bee1a61 467 PRINTS PR00732 Glycosyl hydrolase family 4 signature 112 132 3.4E-45 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CDW54_RS09940 2b4830e3774b8f4975eb63f93bee1a61 467 PRINTS PR00732 Glycosyl hydrolase family 4 signature 141 158 3.4E-45 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CDW54_RS09940 2b4830e3774b8f4975eb63f93bee1a61 467 PRINTS PR00732 Glycosyl hydrolase family 4 signature 167 178 3.4E-45 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CDW54_RS09940 2b4830e3774b8f4975eb63f93bee1a61 467 PRINTS PR00732 Glycosyl hydrolase family 4 signature 77 93 3.4E-45 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CDW54_RS09940 2b4830e3774b8f4975eb63f93bee1a61 467 PRINTS PR00732 Glycosyl hydrolase family 4 signature 6 21 3.4E-45 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CDW54_RS09940 2b4830e3774b8f4975eb63f93bee1a61 467 PRINTS PR00732 Glycosyl hydrolase family 4 signature 98 111 3.4E-45 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CDW54_RS09940 2b4830e3774b8f4975eb63f93bee1a61 467 PRINTS PR00732 Glycosyl hydrolase family 4 signature 193 205 3.4E-45 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CDW54_RS09940 2b4830e3774b8f4975eb63f93bee1a61 467 Pfam PF02056 Family 4 glycosyl hydrolase 6 180 1.5E-64 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CDW54_RS09940 2b4830e3774b8f4975eb63f93bee1a61 467 Gene3D G3DSA:3.90.110.10 160 435 8.4E-86 T 28-03-2018 CDW54_RS09940 2b4830e3774b8f4975eb63f93bee1a61 467 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 141 172 - T 28-03-2018 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 CDW54_RS09940 2b4830e3774b8f4975eb63f93bee1a61 467 Gene3D G3DSA:3.40.50.720 2 159 1.0E-26 T 28-03-2018 CDW54_RS09940 2b4830e3774b8f4975eb63f93bee1a61 467 SUPERFAMILY SSF56327 173 439 2.25E-88 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CDW54_RS04605 ad9989d31aa242507a3d7594cddb38bf 490 Gene3D G3DSA:1.20.1250.20 247 490 2.0E-34 T 28-03-2018 CDW54_RS04605 ad9989d31aa242507a3d7594cddb38bf 490 Pfam PF07690 Major Facilitator Superfamily 14 402 2.1E-58 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDW54_RS04605 ad9989d31aa242507a3d7594cddb38bf 490 SUPERFAMILY SSF103473 243 414 4.05E-72 T 28-03-2018 IPR020846 Major facilitator superfamily domain CDW54_RS04605 ad9989d31aa242507a3d7594cddb38bf 490 SUPERFAMILY SSF103473 8 192 4.05E-72 T 28-03-2018 IPR020846 Major facilitator superfamily domain CDW54_RS04605 ad9989d31aa242507a3d7594cddb38bf 490 SUPERFAMILY SSF103473 458 482 4.05E-72 T 28-03-2018 IPR020846 Major facilitator superfamily domain CDW54_RS04605 ad9989d31aa242507a3d7594cddb38bf 490 Gene3D G3DSA:1.20.1250.20 3 194 2.0E-38 T 28-03-2018 CDW54_RS06145 b8220016e52de71997b3e969a2a4e3f4 560 TIGRFAM TIGR03599 YloV: DAK2 domain fusion protein YloV 11 560 9.4E-218 T 28-03-2018 IPR019986 DAK2 domain-containing protein YloV CDW54_RS06145 b8220016e52de71997b3e969a2a4e3f4 560 Gene3D G3DSA:3.40.50.2300 347 455 0.0016 T 28-03-2018 CDW54_RS06145 b8220016e52de71997b3e969a2a4e3f4 560 SUPERFAMILY SSF101473 4 202 2.75E-47 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CDW54_RS06145 b8220016e52de71997b3e969a2a4e3f4 560 Pfam PF13684 Dihydroxyacetone kinase family 243 560 5.4E-128 T 28-03-2018 IPR033470 Uncharacterised protein, DhaK domain CDW54_RS06145 b8220016e52de71997b3e969a2a4e3f4 560 SMART SM01120 36 201 5.0E-71 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CDW54_RS06145 b8220016e52de71997b3e969a2a4e3f4 560 SMART SM01121 242 560 1.4E-193 T 28-03-2018 IPR033470 Uncharacterised protein, DhaK domain CDW54_RS06145 b8220016e52de71997b3e969a2a4e3f4 560 Pfam PF02734 DAK2 domain 36 200 3.1E-40 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CDW54_RS05695 9e6cdbf807dfe28b02008cb151d18810 823 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 33 472 3.5E-163 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDW54_RS05695 9e6cdbf807dfe28b02008cb151d18810 823 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 9 807 0.0 T 28-03-2018 CDW54_RS05695 9e6cdbf807dfe28b02008cb151d18810 823 SUPERFAMILY SSF56719 32 487 8.11E-183 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CDW54_RS05695 9e6cdbf807dfe28b02008cb151d18810 823 Gene3D G3DSA:1.10.268.10 345 487 9.4E-55 T 28-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDW54_RS05695 9e6cdbf807dfe28b02008cb151d18810 823 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 555 589 1.8E-10 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CDW54_RS05695 9e6cdbf807dfe28b02008cb151d18810 823 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 710 757 7.9E-13 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CDW54_RS05695 9e6cdbf807dfe28b02008cb151d18810 823 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 661 704 1.1E-12 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CDW54_RS05695 9e6cdbf807dfe28b02008cb151d18810 823 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 761 807 4.1E-11 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CDW54_RS05695 9e6cdbf807dfe28b02008cb151d18810 823 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 506 551 1.4E-11 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CDW54_RS05695 9e6cdbf807dfe28b02008cb151d18810 823 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 613 656 3.6E-10 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CDW54_RS05695 9e6cdbf807dfe28b02008cb151d18810 823 Gene3D G3DSA:3.90.199.10 35 214 1.6E-86 T 28-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 CDW54_RS05695 9e6cdbf807dfe28b02008cb151d18810 823 Gene3D G3DSA:3.30.1360.40 237 333 1.1E-35 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CDW54_RS05695 9e6cdbf807dfe28b02008cb151d18810 823 Gene3D G3DSA:2.120.10.90 498 808 1.3E-121 T 28-03-2018 CDW54_RS05695 9e6cdbf807dfe28b02008cb151d18810 823 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 3 810 24.748 T 28-03-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CDW54_RS05695 9e6cdbf807dfe28b02008cb151d18810 823 SUPERFAMILY SSF101904 500 819 4.32E-109 T 28-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal CDW54_RS05695 9e6cdbf807dfe28b02008cb151d18810 823 SMART SM00434 12 465 4.8E-288 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDW54_RS02585 1908d1af5cfe9f801e1f2632fc22e544 380 Gene3D G3DSA:3.90.1150.10 251 365 6.3E-26 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDW54_RS02585 1908d1af5cfe9f801e1f2632fc22e544 380 Gene3D G3DSA:3.40.640.10 10 250 2.1E-53 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDW54_RS02585 1908d1af5cfe9f801e1f2632fc22e544 380 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 193 212 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CDW54_RS02585 1908d1af5cfe9f801e1f2632fc22e544 380 Pfam PF00266 Aminotransferase class-V 2 365 5.9E-72 T 28-03-2018 IPR000192 Aminotransferase class V domain CDW54_RS02585 1908d1af5cfe9f801e1f2632fc22e544 380 SUPERFAMILY SSF53383 1 375 1.16E-96 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDW54_RS02585 1908d1af5cfe9f801e1f2632fc22e544 380 PIRSF PIRSF005572 1 379 3.1E-119 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CDW54_RS02765 80d420fe3e7c0e4168bff9acc10f27b8 1049 Gene3D G3DSA:3.40.50.300 549 953 7.8E-4 T 28-03-2018 CDW54_RS02765 80d420fe3e7c0e4168bff9acc10f27b8 1049 Pfam PF04851 Type III restriction enzyme, res subunit 266 451 3.2E-34 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CDW54_RS02765 80d420fe3e7c0e4168bff9acc10f27b8 1049 SUPERFAMILY SSF52540 287 341 1.59E-9 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS02765 80d420fe3e7c0e4168bff9acc10f27b8 1049 SUPERFAMILY SSF52540 656 759 1.59E-9 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS02765 80d420fe3e7c0e4168bff9acc10f27b8 1049 Gene3D G3DSA:3.40.50.300 261 467 7.3E-23 T 28-03-2018 CDW54_RS02765 80d420fe3e7c0e4168bff9acc10f27b8 1049 Pfam PF12008 Type I restriction and modification enzyme - subunit R C terminal 777 1035 2.0E-33 T 28-03-2018 IPR022625 Type-1 restriction enzyme R protein, C-terminal CDW54_RS02765 80d420fe3e7c0e4168bff9acc10f27b8 1049 SUPERFAMILY SSF52540 227 454 3.84E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS02765 80d420fe3e7c0e4168bff9acc10f27b8 1049 SMART SM00487 264 481 1.0E-16 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CDW54_RS02765 80d420fe3e7c0e4168bff9acc10f27b8 1049 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 91 771 2.1E-101 T 28-03-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 CDW54_RS02765 80d420fe3e7c0e4168bff9acc10f27b8 1049 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 8 209 2.2E-19 T 28-03-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 CDW54_RS05530 9f76c236998566b2ccd4abe03a134ffa 229 SMART SM00448 1 112 5.7E-41 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDW54_RS05530 9f76c236998566b2ccd4abe03a134ffa 229 Gene3D G3DSA:1.10.10.10 120 229 2.7E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS05530 9f76c236998566b2ccd4abe03a134ffa 229 SUPERFAMILY SSF52172 1 122 6.83E-39 T 28-03-2018 IPR011006 CheY-like superfamily CDW54_RS05530 9f76c236998566b2ccd4abe03a134ffa 229 Gene3D G3DSA:3.40.50.2300 1 119 2.5E-35 T 28-03-2018 CDW54_RS05530 9f76c236998566b2ccd4abe03a134ffa 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 226 4.3E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDW54_RS05530 9f76c236998566b2ccd4abe03a134ffa 229 SMART SM00862 150 226 6.4E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDW54_RS05530 9f76c236998566b2ccd4abe03a134ffa 229 Pfam PF00072 Response regulator receiver domain 3 112 6.0E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDW54_RS05530 9f76c236998566b2ccd4abe03a134ffa 229 SUPERFAMILY SSF46894 126 226 3.68E-27 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDW54_RS00390 e1d13d0352555aef7cefffdef67e3af1 192 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 1 187 2.0E-72 T 28-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 CDW54_RS00390 e1d13d0352555aef7cefffdef67e3af1 192 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 2 187 31.851 T 28-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 CDW54_RS00390 e1d13d0352555aef7cefffdef67e3af1 192 Gene3D G3DSA:3.40.50.170 1 186 4.1E-67 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CDW54_RS00390 e1d13d0352555aef7cefffdef67e3af1 192 SUPERFAMILY SSF53328 1 187 2.62E-61 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CDW54_RS00390 e1d13d0352555aef7cefffdef67e3af1 192 Pfam PF00551 Formyl transferase 1 181 4.4E-59 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CDW54_RS11405 d9df5aa5db6af34c0991e80d7c198775 444 Gene3D G3DSA:3.90.190.20 300 444 1.7E-26 T 28-03-2018 CDW54_RS11405 d9df5aa5db6af34c0991e80d7c198775 444 Gene3D G3DSA:3.40.1190.10 94 299 7.5E-36 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CDW54_RS11405 d9df5aa5db6af34c0991e80d7c198775 444 SUPERFAMILY SSF53244 298 435 5.13E-37 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CDW54_RS11405 d9df5aa5db6af34c0991e80d7c198775 444 SUPERFAMILY SSF51984 7 92 2.09E-20 T 28-03-2018 CDW54_RS11405 d9df5aa5db6af34c0991e80d7c198775 444 Pfam PF08245 Mur ligase middle domain 110 279 1.1E-21 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CDW54_RS11405 d9df5aa5db6af34c0991e80d7c198775 444 Pfam PF02875 Mur ligase family, glutamate ligase domain 299 381 8.1E-18 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CDW54_RS11405 d9df5aa5db6af34c0991e80d7c198775 444 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 5 438 34.221 T 28-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDW54_RS11405 d9df5aa5db6af34c0991e80d7c198775 444 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 8 430 5.2E-123 T 28-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDW54_RS11405 d9df5aa5db6af34c0991e80d7c198775 444 Pfam PF01225 Mur ligase family, catalytic domain 8 105 7.1E-22 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CDW54_RS11405 d9df5aa5db6af34c0991e80d7c198775 444 Gene3D G3DSA:3.40.50.720 1 93 3.7E-5 T 28-03-2018 CDW54_RS11405 d9df5aa5db6af34c0991e80d7c198775 444 SUPERFAMILY SSF53623 91 296 4.58E-54 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CDW54_RS07915 31375178960fb9071bc8bc8f7214a455 238 PIRSF PIRSF000161 1 236 6.0E-70 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CDW54_RS07915 31375178960fb9071bc8bc8f7214a455 238 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 30 233 1.7E-54 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CDW54_RS07915 31375178960fb9071bc8bc8f7214a455 238 Gene3D G3DSA:3.40.50.720 1 116 4.1E-15 T 28-03-2018 CDW54_RS07915 31375178960fb9071bc8bc8f7214a455 238 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 125 142 - T 28-03-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CDW54_RS07915 31375178960fb9071bc8bc8f7214a455 238 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 1 234 27.779 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CDW54_RS07915 31375178960fb9071bc8bc8f7214a455 238 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 1 101 9.4E-17 T 28-03-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CDW54_RS07915 31375178960fb9071bc8bc8f7214a455 238 SUPERFAMILY SSF55347 103 204 1.68E-26 T 28-03-2018 CDW54_RS07915 31375178960fb9071bc8bc8f7214a455 238 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 104 233 1.2E-41 T 28-03-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CDW54_RS07915 31375178960fb9071bc8bc8f7214a455 238 Gene3D G3DSA:3.30.360.10 117 203 7.6E-30 T 28-03-2018 CDW54_RS07915 31375178960fb9071bc8bc8f7214a455 238 SUPERFAMILY SSF51735 204 233 6.67E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS07915 31375178960fb9071bc8bc8f7214a455 238 SUPERFAMILY SSF51735 1 100 6.67E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS10825 7d52ac9cee6653354ca2e44bd2bb0218 293 SUPERFAMILY SSF54713 56 145 5.76E-22 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CDW54_RS10825 7d52ac9cee6653354ca2e44bd2bb0218 293 Hamap MF_00050 Elongation factor Ts [tsf]. 1 291 78.444 T 28-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CDW54_RS10825 7d52ac9cee6653354ca2e44bd2bb0218 293 Gene3D G3DSA:3.30.479.20 158 290 2.1E-50 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CDW54_RS10825 7d52ac9cee6653354ca2e44bd2bb0218 293 Gene3D G3DSA:1.10.8.10 1 56 3.1E-22 T 28-03-2018 CDW54_RS10825 7d52ac9cee6653354ca2e44bd2bb0218 293 SUPERFAMILY SSF54713 152 292 3.01E-51 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CDW54_RS10825 7d52ac9cee6653354ca2e44bd2bb0218 293 SUPERFAMILY SSF46934 4 55 1.44E-18 T 28-03-2018 IPR009060 UBA-like GO:0005515 CDW54_RS10825 7d52ac9cee6653354ca2e44bd2bb0218 293 Gene3D G3DSA:3.30.479.20 58 157 2.0E-22 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CDW54_RS10825 7d52ac9cee6653354ca2e44bd2bb0218 293 ProSitePatterns PS01126 Elongation factor Ts signature 1. 12 27 - T 28-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CDW54_RS10825 7d52ac9cee6653354ca2e44bd2bb0218 293 ProSitePatterns PS01127 Elongation factor Ts signature 2. 75 85 - T 28-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CDW54_RS10825 7d52ac9cee6653354ca2e44bd2bb0218 293 Pfam PF00889 Elongation factor TS 71 274 6.0E-73 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CDW54_RS10825 7d52ac9cee6653354ca2e44bd2bb0218 293 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 293 1.7E-102 T 28-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CDW54_RS08935 d6e587db9b597c89bc4c090218a25569 353 Gene3D G3DSA:3.20.20.70 1 233 6.1E-83 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDW54_RS08935 d6e587db9b597c89bc4c090218a25569 353 SUPERFAMILY SSF50891 239 348 8.72E-33 T 28-03-2018 IPR029000 Cyclophilin-like domain CDW54_RS08935 d6e587db9b597c89bc4c090218a25569 353 Gene3D G3DSA:2.40.100.10 240 349 4.7E-32 T 28-03-2018 IPR029000 Cyclophilin-like domain CDW54_RS08935 d6e587db9b597c89bc4c090218a25569 353 Pfam PF05913 Bacterial protein of unknown function (DUF871) 1 347 5.7E-123 T 28-03-2018 IPR008589 Protein of unknown function DUF871, prokaryotic CDW54_RS08935 d6e587db9b597c89bc4c090218a25569 353 SUPERFAMILY SSF51445 1 235 5.69E-76 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CDW54_RS09095 100e4836e961d0975d4f58a59967773e 311 Gene3D G3DSA:3.30.43.10 9 83 5.5E-20 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CDW54_RS09095 100e4836e961d0975d4f58a59967773e 311 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 311 93.527 T 28-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDW54_RS09095 100e4836e961d0975d4f58a59967773e 311 SUPERFAMILY SSF56194 193 298 4.58E-39 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDW54_RS09095 100e4836e961d0975d4f58a59967773e 311 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 198 296 9.4E-30 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDW54_RS09095 100e4836e961d0975d4f58a59967773e 311 Pfam PF01565 FAD binding domain 34 162 9.6E-26 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CDW54_RS09095 100e4836e961d0975d4f58a59967773e 311 Gene3D G3DSA:3.90.78.10 205 296 4.3E-29 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDW54_RS09095 100e4836e961d0975d4f58a59967773e 311 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 21 297 3.5E-75 T 28-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDW54_RS09095 100e4836e961d0975d4f58a59967773e 311 SUPERFAMILY SSF56176 5 190 4.3E-47 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CDW54_RS09095 100e4836e961d0975d4f58a59967773e 311 Gene3D G3DSA:3.30.465.10 84 204 5.3E-39 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CDW54_RS03675 b352ca0b7adfdc2159297c692397813b 611 Gene3D G3DSA:3.30.450.20 247 373 3.2E-21 T 28-03-2018 CDW54_RS03675 b352ca0b7adfdc2159297c692397813b 611 SUPERFAMILY SSF158472 202 251 5.75E-11 T 28-03-2018 CDW54_RS03675 b352ca0b7adfdc2159297c692397813b 611 PRINTS PR00344 Bacterial sensor protein C-terminal signature 588 601 9.7E-20 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDW54_RS03675 b352ca0b7adfdc2159297c692397813b 611 PRINTS PR00344 Bacterial sensor protein C-terminal signature 529 543 9.7E-20 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDW54_RS03675 b352ca0b7adfdc2159297c692397813b 611 PRINTS PR00344 Bacterial sensor protein C-terminal signature 547 557 9.7E-20 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDW54_RS03675 b352ca0b7adfdc2159297c692397813b 611 PRINTS PR00344 Bacterial sensor protein C-terminal signature 564 582 9.7E-20 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDW54_RS03675 b352ca0b7adfdc2159297c692397813b 611 SMART SM00388 377 444 6.5E-22 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDW54_RS03675 b352ca0b7adfdc2159297c692397813b 611 Pfam PF00672 HAMP domain 202 250 4.2E-14 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDW54_RS03675 b352ca0b7adfdc2159297c692397813b 611 Pfam PF00512 His Kinase A (phospho-acceptor) domain 378 444 5.8E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDW54_RS03675 b352ca0b7adfdc2159297c692397813b 611 SUPERFAMILY SSF55874 433 605 5.89E-49 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS03675 b352ca0b7adfdc2159297c692397813b 611 SMART SM00091 261 327 4.6E-10 T 28-03-2018 IPR000014 PAS domain CDW54_RS03675 b352ca0b7adfdc2159297c692397813b 611 Gene3D G3DSA:1.10.287.130 374 438 3.9E-18 T 28-03-2018 CDW54_RS03675 b352ca0b7adfdc2159297c692397813b 611 SMART SM00387 492 604 9.4E-40 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS03675 b352ca0b7adfdc2159297c692397813b 611 Pfam PF00989 PAS fold 262 323 1.2E-8 T 28-03-2018 IPR013767 PAS fold GO:0006355 CDW54_RS03675 b352ca0b7adfdc2159297c692397813b 611 Gene3D G3DSA:3.30.565.10 439 604 8.6E-43 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS03675 b352ca0b7adfdc2159297c692397813b 611 SUPERFAMILY SSF55785 250 369 1.35E-12 T 28-03-2018 IPR000014 PAS domain CDW54_RS03675 b352ca0b7adfdc2159297c692397813b 611 Gene3D G3DSA:3.30.450.20 36 176 1.5E-7 T 28-03-2018 CDW54_RS03675 b352ca0b7adfdc2159297c692397813b 611 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 258 377 1.1E-8 T 28-03-2018 IPR000014 PAS domain CDW54_RS03675 b352ca0b7adfdc2159297c692397813b 611 SUPERFAMILY SSF47384 363 445 3.34E-21 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDW54_RS03675 b352ca0b7adfdc2159297c692397813b 611 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 493 603 9.8E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS03675 b352ca0b7adfdc2159297c692397813b 611 SMART SM00304 202 254 2.7E-16 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDW54_RS12330 3eaa4606ff11024a68815deb2253dfbd 300 Pfam PF03466 LysR substrate binding domain 99 294 6.3E-12 T 28-03-2018 IPR005119 LysR, substrate-binding CDW54_RS12330 3eaa4606ff11024a68815deb2253dfbd 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 9.2E-21 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDW54_RS12330 3eaa4606ff11024a68815deb2253dfbd 300 SUPERFAMILY SSF46785 1 81 8.26E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS12330 3eaa4606ff11024a68815deb2253dfbd 300 Gene3D G3DSA:3.40.190.10 93 186 6.0E-6 T 28-03-2018 CDW54_RS12330 3eaa4606ff11024a68815deb2253dfbd 300 Gene3D G3DSA:3.40.190.10 187 255 0.0015 T 28-03-2018 CDW54_RS12330 3eaa4606ff11024a68815deb2253dfbd 300 SUPERFAMILY SSF53850 90 293 1.28E-17 T 28-03-2018 CDW54_RS12330 3eaa4606ff11024a68815deb2253dfbd 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.1E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDW54_RS12330 3eaa4606ff11024a68815deb2253dfbd 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.1E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDW54_RS12330 3eaa4606ff11024a68815deb2253dfbd 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.1E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDW54_RS12330 3eaa4606ff11024a68815deb2253dfbd 300 Gene3D G3DSA:1.10.10.10 1 92 1.1E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS11250 9f60271b8f7cef6e03c251cc61eda5e7 741 Gene3D G3DSA:3.20.20.70 323 645 2.3E-54 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDW54_RS11250 9f60271b8f7cef6e03c251cc61eda5e7 741 Gene3D G3DSA:2.70.98.60 12 322 4.0E-92 T 28-03-2018 CDW54_RS11250 9f60271b8f7cef6e03c251cc61eda5e7 741 PIRSF PIRSF005536 11 741 8.9E-286 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 CDW54_RS11250 9f60271b8f7cef6e03c251cc61eda5e7 741 Gene3D G3DSA:2.60.40.1180 646 741 2.8E-27 T 28-03-2018 CDW54_RS11250 9f60271b8f7cef6e03c251cc61eda5e7 741 SUPERFAMILY SSF51445 341 677 1.52E-104 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CDW54_RS11250 9f60271b8f7cef6e03c251cc61eda5e7 741 ProSitePatterns PS00512 Alpha-galactosidase signature. 372 387 - T 28-03-2018 IPR000111 Glycoside hydrolase family 27/36, conserved site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CDW54_RS11250 9f60271b8f7cef6e03c251cc61eda5e7 741 Pfam PF16875 Glycosyl hydrolase family 36 N-terminal domain 40 298 4.5E-80 T 28-03-2018 IPR031704 Glycosyl hydrolase family 36, N-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CDW54_RS11250 9f60271b8f7cef6e03c251cc61eda5e7 741 Pfam PF02065 Melibiase 302 648 1.5E-157 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 CDW54_RS11250 9f60271b8f7cef6e03c251cc61eda5e7 741 PRINTS PR00743 Glycosyl hydrolase family 36 signature 343 357 6.9E-61 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 CDW54_RS11250 9f60271b8f7cef6e03c251cc61eda5e7 741 PRINTS PR00743 Glycosyl hydrolase family 36 signature 479 494 6.9E-61 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 CDW54_RS11250 9f60271b8f7cef6e03c251cc61eda5e7 741 PRINTS PR00743 Glycosyl hydrolase family 36 signature 558 574 6.9E-61 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 CDW54_RS11250 9f60271b8f7cef6e03c251cc61eda5e7 741 PRINTS PR00743 Glycosyl hydrolase family 36 signature 371 386 6.9E-61 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 CDW54_RS11250 9f60271b8f7cef6e03c251cc61eda5e7 741 PRINTS PR00743 Glycosyl hydrolase family 36 signature 254 269 6.9E-61 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 CDW54_RS11250 9f60271b8f7cef6e03c251cc61eda5e7 741 PRINTS PR00743 Glycosyl hydrolase family 36 signature 533 549 6.9E-61 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 CDW54_RS11250 9f60271b8f7cef6e03c251cc61eda5e7 741 PRINTS PR00743 Glycosyl hydrolase family 36 signature 421 443 6.9E-61 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 CDW54_RS11250 9f60271b8f7cef6e03c251cc61eda5e7 741 PRINTS PR00743 Glycosyl hydrolase family 36 signature 305 325 6.9E-61 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 CDW54_RS11250 9f60271b8f7cef6e03c251cc61eda5e7 741 Pfam PF16874 Glycosyl hydrolase family 36 C-terminal domain 662 738 1.0E-20 T 28-03-2018 IPR031705 Glycosyl hydrolase family 36, C-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CDW54_RS08830 df8bbb80ad152b82ac72225f5c50aa66 465 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 362 370 - T 28-03-2018 IPR018120 Glycoside hydrolase family 1, active site CDW54_RS08830 df8bbb80ad152b82ac72225f5c50aa66 465 SUPERFAMILY SSF51445 4 464 2.8E-162 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CDW54_RS08830 df8bbb80ad152b82ac72225f5c50aa66 465 PRINTS PR00131 Glycosyl hydrolase family 1 signature 386 397 1.1E-15 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS08830 df8bbb80ad152b82ac72225f5c50aa66 465 PRINTS PR00131 Glycosyl hydrolase family 1 signature 290 304 1.1E-15 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS08830 df8bbb80ad152b82ac72225f5c50aa66 465 PRINTS PR00131 Glycosyl hydrolase family 1 signature 407 424 1.1E-15 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS08830 df8bbb80ad152b82ac72225f5c50aa66 465 PRINTS PR00131 Glycosyl hydrolase family 1 signature 362 370 1.1E-15 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS08830 df8bbb80ad152b82ac72225f5c50aa66 465 PRINTS PR00131 Glycosyl hydrolase family 1 signature 431 443 1.1E-15 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS08830 df8bbb80ad152b82ac72225f5c50aa66 465 Pfam PF00232 Glycosyl hydrolase family 1 4 463 3.7E-130 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS08830 df8bbb80ad152b82ac72225f5c50aa66 465 Gene3D G3DSA:3.20.20.80 4 463 3.4E-145 T 28-03-2018 CDW54_RS01945 c8922c04f9b44402c6aaf0fb84441497 393 SUPERFAMILY SSF55718 286 393 7.85E-22 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CDW54_RS01945 c8922c04f9b44402c6aaf0fb84441497 393 Gene3D G3DSA:3.30.1050.10 281 387 1.0E-24 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CDW54_RS01945 c8922c04f9b44402c6aaf0fb84441497 393 SUPERFAMILY SSF55729 5 285 1.62E-63 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDW54_RS01945 c8922c04f9b44402c6aaf0fb84441497 393 Pfam PF13527 Acetyltransferase (GNAT) domain 5 129 2.0E-35 T 28-03-2018 CDW54_RS01945 c8922c04f9b44402c6aaf0fb84441497 393 Gene3D G3DSA:3.40.630.30 2 132 2.1E-11 T 28-03-2018 CDW54_RS01945 c8922c04f9b44402c6aaf0fb84441497 393 Pfam PF13530 Sterol carrier protein domain 179 389 1.1E-43 T 28-03-2018 IPR025559 Enhanced intracellular survival protein domain CDW54_RS01945 c8922c04f9b44402c6aaf0fb84441497 393 Gene3D G3DSA:3.40.630.30 133 280 6.0E-28 T 28-03-2018 CDW54_RS06370 6982dee7d71bb2e1b68268a21b6e2888 702 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 94 100 - T 28-03-2018 IPR014762 DNA mismatch repair, conserved site CDW54_RS06370 6982dee7d71bb2e1b68268a21b6e2888 702 SUPERFAMILY SSF55874 2 214 6.02E-54 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS06370 6982dee7d71bb2e1b68268a21b6e2888 702 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 209 326 1.8E-35 T 28-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 CDW54_RS06370 6982dee7d71bb2e1b68268a21b6e2888 702 Gene3D G3DSA:3.30.565.10 2 200 8.2E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS06370 6982dee7d71bb2e1b68268a21b6e2888 702 Gene3D G3DSA:3.30.230.10 201 326 8.8E-28 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CDW54_RS06370 6982dee7d71bb2e1b68268a21b6e2888 702 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 3 307 7.2E-98 T 28-03-2018 IPR002099 DNA mismatch repair protein family GO:0005524|GO:0006298|GO:0030983 CDW54_RS06370 6982dee7d71bb2e1b68268a21b6e2888 702 SMART SM01340 209 327 7.1E-51 T 28-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 CDW54_RS06370 6982dee7d71bb2e1b68268a21b6e2888 702 SMART SM00853 513 655 1.7E-52 T 28-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 CDW54_RS06370 6982dee7d71bb2e1b68268a21b6e2888 702 SUPERFAMILY SSF118116 508 697 1.83E-55 T 28-03-2018 CDW54_RS06370 6982dee7d71bb2e1b68268a21b6e2888 702 Pfam PF08676 MutL C terminal dimerisation domain 512 655 2.7E-44 T 28-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 CDW54_RS06370 6982dee7d71bb2e1b68268a21b6e2888 702 SUPERFAMILY SSF54211 191 327 1.29E-35 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CDW54_RS06370 6982dee7d71bb2e1b68268a21b6e2888 702 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 25 125 7.0E-12 T 28-03-2018 CDW54_RS06370 6982dee7d71bb2e1b68268a21b6e2888 702 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 2 695 27.758 T 28-03-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 CDW54_RS10585 79ab09967190a77dfd98c90bd449f928 449 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 204 447 2.0E-89 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CDW54_RS10585 79ab09967190a77dfd98c90bd449f928 449 SUPERFAMILY SSF51735 204 448 5.76E-73 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS10585 79ab09967190a77dfd98c90bd449f928 449 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 115 129 1.6E-29 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CDW54_RS10585 79ab09967190a77dfd98c90bd449f928 449 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 236 256 1.6E-29 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CDW54_RS10585 79ab09967190a77dfd98c90bd449f928 449 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 194 216 1.6E-29 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CDW54_RS10585 79ab09967190a77dfd98c90bd449f928 449 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 373 384 1.6E-29 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CDW54_RS10585 79ab09967190a77dfd98c90bd449f928 449 Gene3D G3DSA:1.10.285.10 375 449 4.7E-25 T 28-03-2018 CDW54_RS10585 79ab09967190a77dfd98c90bd449f928 449 Gene3D G3DSA:1.10.285.10 7 64 0.0099 T 28-03-2018 CDW54_RS10585 79ab09967190a77dfd98c90bd449f928 449 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 123 136 - T 28-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CDW54_RS10585 79ab09967190a77dfd98c90bd449f928 449 SMART SM00839 205 447 3.0E-104 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CDW54_RS10585 79ab09967190a77dfd98c90bd449f928 449 Gene3D G3DSA:3.40.50.720 210 374 2.8E-46 T 28-03-2018 CDW54_RS10585 79ab09967190a77dfd98c90bd449f928 449 PIRSF PIRSF000185 21 449 6.5E-129 T 28-03-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 CDW54_RS10585 79ab09967190a77dfd98c90bd449f928 449 Gene3D G3DSA:3.40.50.10860 65 202 1.9E-56 T 28-03-2018 CDW54_RS10585 79ab09967190a77dfd98c90bd449f928 449 SUPERFAMILY SSF53223 7 197 1.38E-74 T 28-03-2018 CDW54_RS10585 79ab09967190a77dfd98c90bd449f928 449 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 58 186 4.1E-54 T 28-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CDW54_RS06525 27952b34c64dee56d2a9771b3fd12ccf 231 Gene3D G3DSA:1.10.150.240 29 88 5.9E-20 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CDW54_RS06525 27952b34c64dee56d2a9771b3fd12ccf 231 Gene3D G3DSA:3.40.50.1000 1 28 0.37 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS06525 27952b34c64dee56d2a9771b3fd12ccf 231 TIGRFAM TIGR02254 YjjG/YfnB: noncanonical pyrimidine nucleotidase, YjjG family 3 225 2.9E-75 T 28-03-2018 IPR011951 HAD-superfamily hydrolase, subfamily IA, YjjG/YfnB GO:0016787 CDW54_RS06525 27952b34c64dee56d2a9771b3fd12ccf 231 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 113 193 2.2E-11 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDW54_RS06525 27952b34c64dee56d2a9771b3fd12ccf 231 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 198 8.0E-24 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS06525 27952b34c64dee56d2a9771b3fd12ccf 231 Gene3D G3DSA:3.40.50.1000 89 230 9.5E-31 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS06525 27952b34c64dee56d2a9771b3fd12ccf 231 SUPERFAMILY SSF56784 2 226 2.13E-46 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS10780 e49712c87893b890ee3ed0c498af4b51 409 Gene3D G3DSA:3.75.10.10 4 406 8.0E-100 T 28-03-2018 CDW54_RS10780 e49712c87893b890ee3ed0c498af4b51 409 Pfam PF02274 Amidinotransferase 19 405 3.5E-110 T 28-03-2018 CDW54_RS10780 e49712c87893b890ee3ed0c498af4b51 409 SUPERFAMILY SSF55909 3 408 5.1E-138 T 28-03-2018 CDW54_RS10780 e49712c87893b890ee3ed0c498af4b51 409 PIRSF PIRSF006356 1 408 3.2E-161 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CDW54_RS10780 e49712c87893b890ee3ed0c498af4b51 409 Hamap MF_00242 Arginine deiminase [arcA]. 2 408 47.085 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CDW54_RS10780 e49712c87893b890ee3ed0c498af4b51 409 TIGRFAM TIGR01078 arcA: arginine deiminase 5 407 3.7E-172 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CDW54_RS10780 e49712c87893b890ee3ed0c498af4b51 409 PRINTS PR01466 Bacterial arginine deiminase signature 364 378 6.0E-58 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CDW54_RS10780 e49712c87893b890ee3ed0c498af4b51 409 PRINTS PR01466 Bacterial arginine deiminase signature 152 170 6.0E-58 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CDW54_RS10780 e49712c87893b890ee3ed0c498af4b51 409 PRINTS PR01466 Bacterial arginine deiminase signature 180 195 6.0E-58 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CDW54_RS10780 e49712c87893b890ee3ed0c498af4b51 409 PRINTS PR01466 Bacterial arginine deiminase signature 344 361 6.0E-58 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CDW54_RS10780 e49712c87893b890ee3ed0c498af4b51 409 PRINTS PR01466 Bacterial arginine deiminase signature 3 23 6.0E-58 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CDW54_RS10780 e49712c87893b890ee3ed0c498af4b51 409 PRINTS PR01466 Bacterial arginine deiminase signature 387 405 6.0E-58 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CDW54_RS12645 2a23875e8813fa6877ae915b5f6879de 437 Pfam PF09269 Domain of unknown function (DUF1967) 367 435 4.3E-27 T 28-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CDW54_RS12645 2a23875e8813fa6877ae915b5f6879de 437 Hamap MF_01454 GTPase Obg [obg]. 3 339 47.139 T 28-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 CDW54_RS12645 2a23875e8813fa6877ae915b5f6879de 437 Pfam PF01018 GTP1/OBG 6 159 2.6E-58 T 28-03-2018 IPR006169 GTP1/OBG domain CDW54_RS12645 2a23875e8813fa6877ae915b5f6879de 437 Gene3D G3DSA:3.40.50.300 160 343 3.0E-31 T 28-03-2018 CDW54_RS12645 2a23875e8813fa6877ae915b5f6879de 437 SUPERFAMILY SSF82051 3 159 9.16E-55 T 28-03-2018 IPR006169 GTP1/OBG domain CDW54_RS12645 2a23875e8813fa6877ae915b5f6879de 437 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 212 227 1.7E-33 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CDW54_RS12645 2a23875e8813fa6877ae915b5f6879de 437 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 163 183 1.7E-33 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CDW54_RS12645 2a23875e8813fa6877ae915b5f6879de 437 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 184 202 1.7E-33 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CDW54_RS12645 2a23875e8813fa6877ae915b5f6879de 437 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 229 247 1.7E-33 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CDW54_RS12645 2a23875e8813fa6877ae915b5f6879de 437 SUPERFAMILY SSF102741 366 437 4.84E-25 T 28-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CDW54_RS12645 2a23875e8813fa6877ae915b5f6879de 437 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 4 338 6.9E-139 T 28-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 CDW54_RS12645 2a23875e8813fa6877ae915b5f6879de 437 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 162 332 8.9E-12 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CDW54_RS12645 2a23875e8813fa6877ae915b5f6879de 437 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 367 436 1.6E-28 T 28-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CDW54_RS12645 2a23875e8813fa6877ae915b5f6879de 437 Gene3D G3DSA:2.70.210.12 3 157 6.8E-57 T 28-03-2018 IPR006169 GTP1/OBG domain CDW54_RS12645 2a23875e8813fa6877ae915b5f6879de 437 PIRSF PIRSF002401 1 385 3.0E-137 T 28-03-2018 IPR035101 GTP-binding protein, Obg-type CDW54_RS12645 2a23875e8813fa6877ae915b5f6879de 437 SUPERFAMILY SSF52540 152 351 1.12E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS12645 2a23875e8813fa6877ae915b5f6879de 437 ProSitePatterns PS00905 GTP1/OBG family signature. 214 227 - T 28-03-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 CDW54_RS12645 2a23875e8813fa6877ae915b5f6879de 437 Pfam PF01926 50S ribosome-binding GTPase 162 285 6.6E-22 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CDW54_RS00015 92416d92f8ca6325cf66737191b4215e 271 Gene3D G3DSA:3.40.190.10 147 230 1.5E-20 T 28-03-2018 CDW54_RS00015 92416d92f8ca6325cf66737191b4215e 271 SMART SM00079 42 264 2.0E-4 T 28-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 CDW54_RS00015 92416d92f8ca6325cf66737191b4215e 271 SUPERFAMILY SSF53850 5 264 7.62E-72 T 28-03-2018 CDW54_RS00015 92416d92f8ca6325cf66737191b4215e 271 SMART SM00062 42 265 2.9E-73 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CDW54_RS00015 92416d92f8ca6325cf66737191b4215e 271 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 43 263 6.8E-61 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CDW54_RS00015 92416d92f8ca6325cf66737191b4215e 271 Gene3D G3DSA:3.40.190.10 33 146 6.3E-29 T 28-03-2018 CDW54_RS01560 11bf3ad626a3a401df5363bd5ffa9a52 305 SUPERFAMILY SSF55048 124 193 2.35E-17 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CDW54_RS01560 11bf3ad626a3a401df5363bd5ffa9a52 305 SUPERFAMILY SSF52151 186 302 2.62E-73 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CDW54_RS01560 11bf3ad626a3a401df5363bd5ffa9a52 305 SUPERFAMILY SSF52151 3 118 2.62E-73 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CDW54_RS01560 11bf3ad626a3a401df5363bd5ffa9a52 305 Pfam PF00698 Acyl transferase domain 5 276 1.1E-41 T 28-03-2018 IPR014043 Acyl transferase CDW54_RS01560 11bf3ad626a3a401df5363bd5ffa9a52 305 Gene3D G3DSA:3.40.366.10 1 135 3.1E-45 T 28-03-2018 CDW54_RS01560 11bf3ad626a3a401df5363bd5ffa9a52 305 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 6 292 7.5E-48 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CDW54_RS01560 11bf3ad626a3a401df5363bd5ffa9a52 305 Gene3D G3DSA:3.30.70.250 136 185 4.8E-18 T 28-03-2018 CDW54_RS01560 11bf3ad626a3a401df5363bd5ffa9a52 305 PIRSF PIRSF000446 1 305 9.6E-98 T 28-03-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 CDW54_RS01560 11bf3ad626a3a401df5363bd5ffa9a52 305 Gene3D G3DSA:3.40.366.10 186 305 7.1E-24 T 28-03-2018 CDW54_RS01560 11bf3ad626a3a401df5363bd5ffa9a52 305 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 1 285 9.2E-99 T 28-03-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 CDW54_RS07170 e610023bee358c7d0364274b7da508b8 492 PIRSF PIRSF006060 1 482 8.6E-45 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CDW54_RS07170 e610023bee358c7d0364274b7da508b8 492 Pfam PF13520 Amino acid permease 11 441 1.4E-39 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CDW54_RS12590 cf2d1daae4ab38ea0575bcd4e1ca3826 295 Gene3D G3DSA:1.10.530.10 57 213 2.5E-38 T 28-03-2018 CDW54_RS12590 cf2d1daae4ab38ea0575bcd4e1ca3826 295 Gene3D G3DSA:3.10.350.10 236 295 5.2E-15 T 28-03-2018 CDW54_RS12590 cf2d1daae4ab38ea0575bcd4e1ca3826 295 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 71 209 1.7E-20 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CDW54_RS12590 cf2d1daae4ab38ea0575bcd4e1ca3826 295 SUPERFAMILY SSF54106 249 295 6.41E-11 T 28-03-2018 IPR018392 LysM domain CDW54_RS12590 cf2d1daae4ab38ea0575bcd4e1ca3826 295 Pfam PF01476 LysM domain 252 295 3.2E-13 T 28-03-2018 IPR018392 LysM domain CDW54_RS12590 cf2d1daae4ab38ea0575bcd4e1ca3826 295 SMART SM00257 251 295 6.0E-11 T 28-03-2018 IPR018392 LysM domain CDW54_RS12590 cf2d1daae4ab38ea0575bcd4e1ca3826 295 SMART SM00047 50 213 5.7E-52 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CDW54_RS07590 51017f415d4d51efca28f37f30ca536e 176 Gene3D G3DSA:2.40.128.20 8 160 2.6E-62 T 28-03-2018 IPR012674 Calycin CDW54_RS07590 51017f415d4d51efca28f37f30ca536e 176 Pfam PF05870 Phenolic acid decarboxylase (PAD) 7 164 1.3E-77 T 28-03-2018 IPR008729 Phenolic acid decarboxylase, bacterial GO:0016831 CDW54_RS07590 51017f415d4d51efca28f37f30ca536e 176 PIRSF PIRSF011561 1 176 1.5E-101 T 28-03-2018 IPR008729 Phenolic acid decarboxylase, bacterial GO:0016831 CDW54_RS07590 51017f415d4d51efca28f37f30ca536e 176 SUPERFAMILY SSF50814 3 175 5.23E-77 T 28-03-2018 IPR012674 Calycin CDW54_RS07590 51017f415d4d51efca28f37f30ca536e 176 ProDom PD022010 DECARBOXYLASE ACID PHENOLIC P-COUMARIC LYASE 4.1.1.- PAD PADC FERULATE PROBABLE 7 166 2.0E-90 T 28-03-2018 IPR008729 Phenolic acid decarboxylase, bacterial GO:0016831 CDW54_RS06270 04fc87e28f65232e36ad33054c7cfb1a 365 Gene3D G3DSA:2.60.40.1710 27 175 5.1E-6 T 28-03-2018 CDW54_RS06270 04fc87e28f65232e36ad33054c7cfb1a 365 Pfam PF06030 Bacterial protein of unknown function (DUF916) 38 157 9.3E-40 T 28-03-2018 IPR010317 Protein of unknown function DUF916, cell surface putative CDW54_RS06270 04fc87e28f65232e36ad33054c7cfb1a 365 Pfam PF11797 Protein of unknown function C-terminal (DUF3324) 170 323 3.0E-47 T 28-03-2018 IPR021759 Domain of unknown function DUF3324, C-terminal CDW54_RS12010 4a2a9304399385887f38474361f44791 388 Pfam PF02353 Mycolic acid cyclopropane synthetase 107 372 9.8E-100 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDW54_RS12010 4a2a9304399385887f38474361f44791 388 Gene3D G3DSA:3.40.50.150 104 377 4.1E-64 T 28-03-2018 CDW54_RS12010 4a2a9304399385887f38474361f44791 388 PIRSF PIRSF003085 5 387 2.7E-126 T 28-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 CDW54_RS12010 4a2a9304399385887f38474361f44791 388 SUPERFAMILY SSF53335 2 332 4.93E-81 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDW54_RS11850 0ec9a5db6b0f2d83a959d26d64396479 404 TIGRFAM TIGR00836 amt: ammonium transporter 10 397 3.7E-104 T 28-03-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 CDW54_RS11850 0ec9a5db6b0f2d83a959d26d64396479 404 Gene3D G3DSA:1.10.3430.10 3 383 7.8E-107 T 28-03-2018 CDW54_RS11850 0ec9a5db6b0f2d83a959d26d64396479 404 SUPERFAMILY SSF111352 6 375 2.09E-103 T 28-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 CDW54_RS11850 0ec9a5db6b0f2d83a959d26d64396479 404 Pfam PF00909 Ammonium Transporter Family 12 399 4.1E-96 T 28-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 CDW54_RS02985 7583175cff85bf7f77100954cc7ce062 493 Gene3D G3DSA:1.10.10.10 1 71 7.4E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS02985 7583175cff85bf7f77100954cc7ce062 493 Gene3D G3DSA:1.10.10.10 88 152 0.0016 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS02985 7583175cff85bf7f77100954cc7ce062 493 Pfam PF05043 Mga helix-turn-helix domain 88 166 1.5E-8 T 28-03-2018 IPR007737 Mga helix-turn-helix domain CDW54_RS00010 0c7e722417fcbabf806fc39f743fba61 215 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 10 106 3.8E-26 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CDW54_RS00010 0c7e722417fcbabf806fc39f743fba61 215 SUPERFAMILY SSF161098 10 198 1.2E-47 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS00010 0c7e722417fcbabf806fc39f743fba61 215 Gene3D G3DSA:1.10.3720.10 2 215 2.3E-49 T 28-03-2018 CDW54_RS00010 0c7e722417fcbabf806fc39f743fba61 215 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 31 211 2.6E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS03860 6a20de0eaa53daa1793d07e845f8afef 295 Pfam PF06028 Alpha/beta hydrolase of unknown function (DUF915) 49 295 9.9E-78 T 28-03-2018 IPR010315 Protein of unknown function DUF915, hydrolase-like CDW54_RS03860 6a20de0eaa53daa1793d07e845f8afef 295 SUPERFAMILY SSF53474 57 96 2.96E-19 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CDW54_RS03860 6a20de0eaa53daa1793d07e845f8afef 295 SUPERFAMILY SSF53474 123 291 2.96E-19 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CDW54_RS03860 6a20de0eaa53daa1793d07e845f8afef 295 Gene3D G3DSA:3.40.50.1820 52 295 5.0E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CDW54_RS12675 6ee73f55c289308b431cdb0d641fd933 251 PIRSF PIRSF000094 1 251 2.5E-90 T 28-03-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CDW54_RS12675 6ee73f55c289308b431cdb0d641fd933 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 5.6E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS12675 6ee73f55c289308b431cdb0d641fd933 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 5.6E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS12675 6ee73f55c289308b431cdb0d641fd933 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 5.6E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS12675 6ee73f55c289308b431cdb0d641fd933 251 SUPERFAMILY SSF51735 5 250 2.05E-60 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS12675 6ee73f55c289308b431cdb0d641fd933 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 249 5.6E-74 T 28-03-2018 CDW54_RS12675 6ee73f55c289308b431cdb0d641fd933 251 Gene3D G3DSA:3.40.50.720 1 251 7.6E-39 T 28-03-2018 CDW54_RS01805 d9e0032cca603b18ef099f7031d6592b 325 Gene3D G3DSA:3.90.550.10 3 306 1.0E-54 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDW54_RS01805 d9e0032cca603b18ef099f7031d6592b 325 Pfam PF00535 Glycosyl transferase family 2 5 168 3.0E-35 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CDW54_RS01805 d9e0032cca603b18ef099f7031d6592b 325 SUPERFAMILY SSF53448 4 231 7.31E-53 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDW54_RS09840 6bbb028676fcb44c1bb67cee89a10334 312 Gene3D G3DSA:3.40.1390.20 4 134 1.7E-41 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CDW54_RS09840 6bbb028676fcb44c1bb67cee89a10334 312 Pfam PF07475 HPr Serine kinase C-terminal domain 132 300 2.5E-74 T 28-03-2018 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 CDW54_RS09840 6bbb028676fcb44c1bb67cee89a10334 312 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 5 303 4.4E-112 T 28-03-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 CDW54_RS09840 6bbb028676fcb44c1bb67cee89a10334 312 Gene3D G3DSA:3.40.50.300 137 309 1.3E-42 T 28-03-2018 CDW54_RS09840 6bbb028676fcb44c1bb67cee89a10334 312 Hamap MF_01249 HPr kinase/phosphorylase [hprK]. 4 308 41.809 T 28-03-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 CDW54_RS09840 6bbb028676fcb44c1bb67cee89a10334 312 SUPERFAMILY SSF53795 134 300 1.07E-39 T 28-03-2018 CDW54_RS09840 6bbb028676fcb44c1bb67cee89a10334 312 Pfam PF02603 HPr Serine kinase N terminus 5 129 1.1E-39 T 28-03-2018 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 CDW54_RS09840 6bbb028676fcb44c1bb67cee89a10334 312 SUPERFAMILY SSF75138 5 133 1.83E-38 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CDW54_RS04190 5c1ce9972bfc015c8d9c9c491da01117 220 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 26 209 3.2E-57 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CDW54_RS04190 5c1ce9972bfc015c8d9c9c491da01117 220 Pfam PF02390 Putative methyltransferase 39 206 1.4E-46 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CDW54_RS04190 5c1ce9972bfc015c8d9c9c491da01117 220 SUPERFAMILY SSF53335 31 209 1.0E-29 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDW54_RS04190 5c1ce9972bfc015c8d9c9c491da01117 220 Gene3D G3DSA:3.40.50.150 1 211 1.8E-32 T 28-03-2018 CDW54_RS04190 5c1ce9972bfc015c8d9c9c491da01117 220 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 1 212 29.718 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CDW54_RS10385 6113f83b5c0e517e56d21e3188d1aebc 173 SUPERFAMILY SSF53597 2 171 5.76E-35 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CDW54_RS10385 6113f83b5c0e517e56d21e3188d1aebc 173 Pfam PF01872 RibD C-terminal domain 2 164 1.3E-19 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CDW54_RS10385 6113f83b5c0e517e56d21e3188d1aebc 173 Gene3D G3DSA:3.40.430.10 1 173 1.3E-36 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CDW54_RS01375 41b4c97fe8d1c766ff2c81b36b9e608b 501 Gene3D G3DSA:1.10.287.130 263 336 1.1E-14 T 28-03-2018 CDW54_RS01375 41b4c97fe8d1c766ff2c81b36b9e608b 501 Gene3D G3DSA:3.30.565.10 344 501 1.1E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS01375 41b4c97fe8d1c766ff2c81b36b9e608b 501 SUPERFAMILY SSF158472 220 268 5.1E-5 T 28-03-2018 CDW54_RS01375 41b4c97fe8d1c766ff2c81b36b9e608b 501 SUPERFAMILY SSF55874 330 496 1.76E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS01375 41b4c97fe8d1c766ff2c81b36b9e608b 501 Pfam PF00672 HAMP domain 220 267 1.6E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDW54_RS01375 41b4c97fe8d1c766ff2c81b36b9e608b 501 SMART SM00388 273 340 3.0E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDW54_RS01375 41b4c97fe8d1c766ff2c81b36b9e608b 501 SUPERFAMILY SSF47384 256 338 3.34E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDW54_RS01375 41b4c97fe8d1c766ff2c81b36b9e608b 501 Pfam PF00512 His Kinase A (phospho-acceptor) domain 274 339 6.3E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDW54_RS01375 41b4c97fe8d1c766ff2c81b36b9e608b 501 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 388 495 2.4E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS01375 41b4c97fe8d1c766ff2c81b36b9e608b 501 PRINTS PR00344 Bacterial sensor protein C-terminal signature 440 450 1.7E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDW54_RS01375 41b4c97fe8d1c766ff2c81b36b9e608b 501 PRINTS PR00344 Bacterial sensor protein C-terminal signature 481 494 1.7E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDW54_RS01375 41b4c97fe8d1c766ff2c81b36b9e608b 501 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 436 1.7E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDW54_RS01375 41b4c97fe8d1c766ff2c81b36b9e608b 501 PRINTS PR00344 Bacterial sensor protein C-terminal signature 457 475 1.7E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDW54_RS01375 41b4c97fe8d1c766ff2c81b36b9e608b 501 SMART SM00387 385 497 1.7E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS01375 41b4c97fe8d1c766ff2c81b36b9e608b 501 SMART SM00304 218 272 3.1E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDW54_RS03705 3bba0fcee99791c8ed2ac98a97c1cfe5 324 Gene3D G3DSA:3.60.60.10 2 324 5.7E-88 T 28-03-2018 CDW54_RS03705 3bba0fcee99791c8ed2ac98a97c1cfe5 324 Pfam PF02275 Linear amide C-N hydrolases, choloylglycine hydrolase family 2 312 3.0E-111 T 28-03-2018 IPR029132 Choloylglycine hydrolase/NAAA C-terminal CDW54_RS03705 3bba0fcee99791c8ed2ac98a97c1cfe5 324 SUPERFAMILY SSF56235 2 324 4.24E-110 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CDW54_RS10320 3bba0fcee99791c8ed2ac98a97c1cfe5 324 Gene3D G3DSA:3.60.60.10 2 324 5.7E-88 T 28-03-2018 CDW54_RS10320 3bba0fcee99791c8ed2ac98a97c1cfe5 324 Pfam PF02275 Linear amide C-N hydrolases, choloylglycine hydrolase family 2 312 3.0E-111 T 28-03-2018 IPR029132 Choloylglycine hydrolase/NAAA C-terminal CDW54_RS10320 3bba0fcee99791c8ed2ac98a97c1cfe5 324 SUPERFAMILY SSF56235 2 324 4.24E-110 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CDW54_RS08090 8d63cb0fa9aeb6be5ee72ef2901215d0 191 Gene3D G3DSA:3.90.1680.10 1 190 2.1E-40 T 28-03-2018 IPR003738 SOS response associated peptidase (SRAP) CDW54_RS08090 8d63cb0fa9aeb6be5ee72ef2901215d0 191 SUPERFAMILY SSF143081 2 170 2.62E-39 T 28-03-2018 IPR003738 SOS response associated peptidase (SRAP) CDW54_RS08090 8d63cb0fa9aeb6be5ee72ef2901215d0 191 Pfam PF02586 SOS response associated peptidase (SRAP) 1 171 1.3E-32 T 28-03-2018 IPR003738 SOS response associated peptidase (SRAP) CDW54_RS04120 42bc3ef11d24e6acdba170bc9a8cd714 159 PRINTS PR01438 Universal stress protein signature 104 116 2.9E-20 T 28-03-2018 IPR006015 Universal stress protein A CDW54_RS04120 42bc3ef11d24e6acdba170bc9a8cd714 159 PRINTS PR01438 Universal stress protein signature 122 144 2.9E-20 T 28-03-2018 IPR006015 Universal stress protein A CDW54_RS04120 42bc3ef11d24e6acdba170bc9a8cd714 159 PRINTS PR01438 Universal stress protein signature 5 23 2.9E-20 T 28-03-2018 IPR006015 Universal stress protein A CDW54_RS04120 42bc3ef11d24e6acdba170bc9a8cd714 159 PIRSF PIRSF006276 1 146 4.9E-20 T 28-03-2018 IPR006015 Universal stress protein A CDW54_RS04120 42bc3ef11d24e6acdba170bc9a8cd714 159 SUPERFAMILY SSF52402 5 146 1.84E-35 T 28-03-2018 CDW54_RS04120 42bc3ef11d24e6acdba170bc9a8cd714 159 Pfam PF00582 Universal stress protein family 5 144 2.1E-39 T 28-03-2018 IPR006016 UspA GO:0006950 CDW54_RS04120 42bc3ef11d24e6acdba170bc9a8cd714 159 Gene3D G3DSA:3.40.50.620 1 147 2.8E-37 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDW54_RS09565 7d76d32f1831deacf1f9310a06ec2f8a 333 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 325 3.4E-135 T 28-03-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDW54_RS09565 7d76d32f1831deacf1f9310a06ec2f8a 333 SUPERFAMILY SSF55347 150 313 1.9E-65 T 28-03-2018 CDW54_RS09565 7d76d32f1831deacf1f9310a06ec2f8a 333 Gene3D G3DSA:3.30.360.10 161 315 3.3E-61 T 28-03-2018 CDW54_RS09565 7d76d32f1831deacf1f9310a06ec2f8a 333 PIRSF PIRSF000149 1 333 1.6E-120 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDW54_RS09565 7d76d32f1831deacf1f9310a06ec2f8a 333 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 103 6.3E-40 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDW54_RS09565 7d76d32f1831deacf1f9310a06ec2f8a 333 SUPERFAMILY SSF51735 3 167 6.68E-63 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS09565 7d76d32f1831deacf1f9310a06ec2f8a 333 SMART SM00846 3 151 1.4E-91 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDW54_RS09565 7d76d32f1831deacf1f9310a06ec2f8a 333 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 149 156 - T 28-03-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDW54_RS09565 7d76d32f1831deacf1f9310a06ec2f8a 333 Gene3D G3DSA:3.40.50.720 1 160 5.5E-77 T 28-03-2018 CDW54_RS09565 7d76d32f1831deacf1f9310a06ec2f8a 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 266 281 6.1E-32 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDW54_RS09565 7d76d32f1831deacf1f9310a06ec2f8a 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 145 163 6.1E-32 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDW54_RS09565 7d76d32f1831deacf1f9310a06ec2f8a 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 172 188 6.1E-32 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDW54_RS09565 7d76d32f1831deacf1f9310a06ec2f8a 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 230 247 6.1E-32 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDW54_RS09565 7d76d32f1831deacf1f9310a06ec2f8a 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 109 122 6.1E-32 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDW54_RS09565 7d76d32f1831deacf1f9310a06ec2f8a 333 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 156 313 4.4E-63 T 28-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDW54_RS11410 787b2dbb736898f38a0d2a8c2f9530fb 161 SUPERFAMILY SSF54637 14 142 6.39E-26 T 28-03-2018 IPR029069 HotDog domain CDW54_RS11410 787b2dbb736898f38a0d2a8c2f9530fb 161 Pfam PF01575 MaoC like domain 24 127 6.3E-13 T 28-03-2018 IPR002539 MaoC-like domain CDW54_RS11410 787b2dbb736898f38a0d2a8c2f9530fb 161 Gene3D G3DSA:3.10.129.10 11 144 3.0E-24 T 28-03-2018 CDW54_RS06475 c7a2e7a20113ce0df27b4ed4bc589c5b 187 PRINTS PR01576 Peptide deformylase signature 144 173 5.7E-29 T 28-03-2018 IPR023635 Peptide deformylase CDW54_RS06475 c7a2e7a20113ce0df27b4ed4bc589c5b 187 PRINTS PR01576 Peptide deformylase signature 47 76 5.7E-29 T 28-03-2018 IPR023635 Peptide deformylase CDW54_RS06475 c7a2e7a20113ce0df27b4ed4bc589c5b 187 PRINTS PR01576 Peptide deformylase signature 125 143 5.7E-29 T 28-03-2018 IPR023635 Peptide deformylase CDW54_RS06475 c7a2e7a20113ce0df27b4ed4bc589c5b 187 PRINTS PR01576 Peptide deformylase signature 112 123 5.7E-29 T 28-03-2018 IPR023635 Peptide deformylase CDW54_RS06475 c7a2e7a20113ce0df27b4ed4bc589c5b 187 Hamap MF_00163 Peptide deformylase [def]. 3 186 26.284 T 28-03-2018 IPR023635 Peptide deformylase CDW54_RS06475 c7a2e7a20113ce0df27b4ed4bc589c5b 187 Pfam PF01327 Polypeptide deformylase 5 175 4.5E-44 T 28-03-2018 IPR023635 Peptide deformylase CDW54_RS06475 c7a2e7a20113ce0df27b4ed4bc589c5b 187 PIRSF PIRSF004749 2 187 1.9E-43 T 28-03-2018 IPR023635 Peptide deformylase CDW54_RS06475 c7a2e7a20113ce0df27b4ed4bc589c5b 187 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 6 181 1.6E-41 T 28-03-2018 IPR023635 Peptide deformylase CDW54_RS06475 c7a2e7a20113ce0df27b4ed4bc589c5b 187 SUPERFAMILY SSF56420 2 183 1.02E-55 T 28-03-2018 IPR023635 Peptide deformylase CDW54_RS06475 c7a2e7a20113ce0df27b4ed4bc589c5b 187 Gene3D G3DSA:3.90.45.10 3 187 1.7E-50 T 28-03-2018 IPR023635 Peptide deformylase CDW54_RS10985 9e503db1d660aed0f26923caacf79be7 187 SUPERFAMILY SSF51064 131 187 8.24E-18 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CDW54_RS10985 9e503db1d660aed0f26923caacf79be7 187 ProSitePatterns PS01071 grpE protein signature. 141 185 - T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CDW54_RS10985 9e503db1d660aed0f26923caacf79be7 187 Hamap MF_01151 Protein GrpE [grpE]. 3 187 20.804 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CDW54_RS10985 9e503db1d660aed0f26923caacf79be7 187 Gene3D G3DSA:3.90.20.20 24 128 1.2E-23 T 28-03-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 CDW54_RS10985 9e503db1d660aed0f26923caacf79be7 187 PRINTS PR00773 GrpE protein signature 138 153 3.0E-26 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CDW54_RS10985 9e503db1d660aed0f26923caacf79be7 187 PRINTS PR00773 GrpE protein signature 56 72 3.0E-26 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CDW54_RS10985 9e503db1d660aed0f26923caacf79be7 187 PRINTS PR00773 GrpE protein signature 84 99 3.0E-26 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CDW54_RS10985 9e503db1d660aed0f26923caacf79be7 187 PRINTS PR00773 GrpE protein signature 166 185 3.0E-26 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CDW54_RS10985 9e503db1d660aed0f26923caacf79be7 187 SUPERFAMILY SSF58014 36 130 2.09E-22 T 28-03-2018 CDW54_RS10985 9e503db1d660aed0f26923caacf79be7 187 Pfam PF01025 GrpE 32 187 1.2E-52 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CDW54_RS10985 9e503db1d660aed0f26923caacf79be7 187 Gene3D G3DSA:2.30.22.10 130 187 3.7E-24 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CDW54_RS09075 8d9f2603d245e75192bf8cbc0ebeecad 177 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 4 163 4.1E-22 T 28-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDW54_RS09075 8d9f2603d245e75192bf8cbc0ebeecad 177 SMART SM00479 2 167 6.5E-25 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CDW54_RS09075 8d9f2603d245e75192bf8cbc0ebeecad 177 Gene3D G3DSA:3.30.420.10 1 173 2.0E-35 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS09075 8d9f2603d245e75192bf8cbc0ebeecad 177 Pfam PF00929 Exonuclease 4 158 6.8E-24 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CDW54_RS09075 8d9f2603d245e75192bf8cbc0ebeecad 177 SUPERFAMILY SSF53098 1 166 8.81E-44 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS00930 3b25f956af3d360a9b3bd797482d202e 211 SUPERFAMILY SSF54106 168 210 2.62E-6 T 28-03-2018 IPR018392 LysM domain CDW54_RS00930 3b25f956af3d360a9b3bd797482d202e 211 Pfam PF01476 LysM domain 168 210 1.4E-7 T 28-03-2018 IPR018392 LysM domain CDW54_RS00930 3b25f956af3d360a9b3bd797482d202e 211 Gene3D G3DSA:3.10.350.10 153 211 6.7E-11 T 28-03-2018 CDW54_RS00930 3b25f956af3d360a9b3bd797482d202e 211 SMART SM00257 166 211 5.9E-5 T 28-03-2018 IPR018392 LysM domain CDW54_RS01410 efed58a4825bea6e146c88800c2775a7 320 PIRSF PIRSF000532 1 319 1.7E-116 T 28-03-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CDW54_RS01410 efed58a4825bea6e146c88800c2775a7 320 Gene3D G3DSA:3.40.50.450 200 300 4.7E-15 T 28-03-2018 CDW54_RS01410 efed58a4825bea6e146c88800c2775a7 320 Hamap MF_00339 ATP-dependent 6-phosphofructokinase [pfkA]. 1 319 48.431 T 28-03-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CDW54_RS01410 efed58a4825bea6e146c88800c2775a7 320 SUPERFAMILY SSF53784 1 307 7.19E-111 T 28-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CDW54_RS01410 efed58a4825bea6e146c88800c2775a7 320 Gene3D G3DSA:3.40.50.450 1 199 2.7E-82 T 28-03-2018 CDW54_RS01410 efed58a4825bea6e146c88800c2775a7 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 212 224 1.0E-83 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CDW54_RS01410 efed58a4825bea6e146c88800c2775a7 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 1.0E-83 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CDW54_RS01410 efed58a4825bea6e146c88800c2775a7 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 239 261 1.0E-83 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CDW54_RS01410 efed58a4825bea6e146c88800c2775a7 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 1.0E-83 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CDW54_RS01410 efed58a4825bea6e146c88800c2775a7 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 1.0E-83 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CDW54_RS01410 efed58a4825bea6e146c88800c2775a7 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 1.0E-83 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CDW54_RS01410 efed58a4825bea6e146c88800c2775a7 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 1.0E-83 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CDW54_RS01410 efed58a4825bea6e146c88800c2775a7 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 6 25 1.0E-83 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CDW54_RS01410 efed58a4825bea6e146c88800c2775a7 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 1.0E-83 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CDW54_RS01410 efed58a4825bea6e146c88800c2775a7 320 TIGRFAM TIGR02482 PFKA_ATP: 6-phosphofructokinase 3 299 2.1E-126 T 28-03-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CDW54_RS01410 efed58a4825bea6e146c88800c2775a7 320 Pfam PF00365 Phosphofructokinase 3 275 1.7E-107 T 28-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CDW54_RS11450 8be49df46540548c687d9046e770428f 308 Pfam PF07319 Primosomal protein DnaI N-terminus 1 94 2.9E-32 T 28-03-2018 IPR009928 Primosomal DnaI, N-terminal CDW54_RS11450 8be49df46540548c687d9046e770428f 308 Gene3D G3DSA:3.40.50.300 104 300 9.7E-18 T 28-03-2018 CDW54_RS11450 8be49df46540548c687d9046e770428f 308 Pfam PF01695 IstB-like ATP binding protein 108 271 8.9E-14 T 28-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 CDW54_RS11450 8be49df46540548c687d9046e770428f 308 SUPERFAMILY SSF52540 122 271 3.03E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS05975 96e8d54c290bfd27950a897f163b0a60 102 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 99 4.0E-28 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS05975 96e8d54c290bfd27950a897f163b0a60 102 SUPERFAMILY SSF50104 2 99 2.41E-33 T 28-03-2018 IPR008991 Translation protein SH3-like domain CDW54_RS05975 96e8d54c290bfd27950a897f163b0a60 102 ProSitePatterns PS01108 Ribosomal protein L24 signature. 6 23 - T 28-03-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS05975 96e8d54c290bfd27950a897f163b0a60 102 Gene3D G3DSA:2.30.30.30 1 90 5.4E-32 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 CDW54_RS05975 96e8d54c290bfd27950a897f163b0a60 102 Pfam PF00467 KOW motif 5 36 8.1E-7 T 28-03-2018 IPR005824 KOW CDW54_RS05975 96e8d54c290bfd27950a897f163b0a60 102 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 94 21.807 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS05975 96e8d54c290bfd27950a897f163b0a60 102 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 3 99 2.7E-35 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS05975 96e8d54c290bfd27950a897f163b0a60 102 SMART SM00739 2 29 8.4E-5 T 28-03-2018 IPR005824 KOW CDW54_RS08890 a02442b7adc2de7b5b5d83d599a7f36f 472 Pfam PF03553 Na+/H+ antiporter family 159 451 8.5E-46 T 28-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 CDW54_RS08890 a02442b7adc2de7b5b5d83d599a7f36f 472 TIGRFAM TIGR00931 antiport_nhaC: Na+/H+ antiporter NhaC 7 455 1.2E-117 T 28-03-2018 IPR004770 Na+/H+ antiporter NhaC GO:0015297|GO:0016021 CDW54_RS03045 c2868269b83ef4638666c017a8f08b01 394 Gene3D G3DSA:3.20.20.140 70 327 5.3E-119 T 28-03-2018 CDW54_RS03045 c2868269b83ef4638666c017a8f08b01 394 Gene3D G3DSA:2.30.40.10 328 387 2.0E-11 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CDW54_RS03045 c2868269b83ef4638666c017a8f08b01 394 SUPERFAMILY SSF51556 56 348 3.13E-77 T 28-03-2018 IPR032466 Metal-dependent hydrolase CDW54_RS03045 c2868269b83ef4638666c017a8f08b01 394 PIRSF PIRSF001238 1 392 2.0E-156 T 28-03-2018 IPR010229 Peptidase M38, beta-aspartyl dipeptidase GO:0008798 CDW54_RS03045 c2868269b83ef4638666c017a8f08b01 394 TIGRFAM TIGR01975 isoAsp_dipep: beta-aspartyl peptidase 2 391 2.1E-158 T 28-03-2018 IPR010229 Peptidase M38, beta-aspartyl dipeptidase GO:0008798 CDW54_RS03045 c2868269b83ef4638666c017a8f08b01 394 SUPERFAMILY SSF51338 2 55 1.36E-17 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CDW54_RS03045 c2868269b83ef4638666c017a8f08b01 394 SUPERFAMILY SSF51338 348 391 1.36E-17 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CDW54_RS03045 c2868269b83ef4638666c017a8f08b01 394 Gene3D G3DSA:2.30.40.10 2 69 1.2E-12 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CDW54_RS03045 c2868269b83ef4638666c017a8f08b01 394 Pfam PF01979 Amidohydrolase family 52 377 1.3E-14 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CDW54_RS03260 9a3ae434142bdfbc9cfc9e72909640da 810 SUPERFAMILY SSF46785 734 799 1.26E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS03260 9a3ae434142bdfbc9cfc9e72909640da 810 Pfam PF01580 FtsK/SpoIIIE family 444 635 2.6E-59 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CDW54_RS03260 9a3ae434142bdfbc9cfc9e72909640da 810 SUPERFAMILY SSF52540 413 707 3.32E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS03260 9a3ae434142bdfbc9cfc9e72909640da 810 SMART SM00382 474 656 8.7E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS03260 9a3ae434142bdfbc9cfc9e72909640da 810 Gene3D G3DSA:3.40.50.300 210 734 1.6E-52 T 28-03-2018 CDW54_RS03260 9a3ae434142bdfbc9cfc9e72909640da 810 SMART SM00843 733 798 1.4E-39 T 28-03-2018 IPR018541 FtsK gamma domain CDW54_RS03260 9a3ae434142bdfbc9cfc9e72909640da 810 Gene3D G3DSA:1.10.10.10 735 789 5.3E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS03260 9a3ae434142bdfbc9cfc9e72909640da 810 Pfam PF09397 Ftsk gamma domain 736 795 1.4E-29 T 28-03-2018 IPR018541 FtsK gamma domain CDW54_RS00920 55f59f18216552d9fdd06684250b2c45 409 Gene3D G3DSA:2.40.50.140 289 407 1.6E-26 T 28-03-2018 CDW54_RS00920 55f59f18216552d9fdd06684250b2c45 409 Gene3D G3DSA:2.40.50.140 204 288 1.2E-24 T 28-03-2018 CDW54_RS00920 55f59f18216552d9fdd06684250b2c45 409 Pfam PF00575 S1 RNA binding domain 203 272 6.1E-21 T 28-03-2018 IPR003029 S1 domain GO:0003676 CDW54_RS00920 55f59f18216552d9fdd06684250b2c45 409 Pfam PF00575 S1 RNA binding domain 24 85 2.4E-10 T 28-03-2018 IPR003029 S1 domain GO:0003676 CDW54_RS00920 55f59f18216552d9fdd06684250b2c45 409 Pfam PF00575 S1 RNA binding domain 286 358 4.5E-22 T 28-03-2018 IPR003029 S1 domain GO:0003676 CDW54_RS00920 55f59f18216552d9fdd06684250b2c45 409 Pfam PF00575 S1 RNA binding domain 115 183 2.1E-13 T 28-03-2018 IPR003029 S1 domain GO:0003676 CDW54_RS00920 55f59f18216552d9fdd06684250b2c45 409 SMART SM00316 202 272 4.0E-25 T 28-03-2018 IPR022967 RNA-binding domain, S1 CDW54_RS00920 55f59f18216552d9fdd06684250b2c45 409 SMART SM00316 287 358 5.8E-27 T 28-03-2018 IPR022967 RNA-binding domain, S1 CDW54_RS00920 55f59f18216552d9fdd06684250b2c45 409 SMART SM00316 116 183 4.5E-11 T 28-03-2018 IPR022967 RNA-binding domain, S1 CDW54_RS00920 55f59f18216552d9fdd06684250b2c45 409 SMART SM00316 25 100 2.7E-11 T 28-03-2018 IPR022967 RNA-binding domain, S1 CDW54_RS00920 55f59f18216552d9fdd06684250b2c45 409 Gene3D G3DSA:2.40.50.140 17 106 2.8E-14 T 28-03-2018 CDW54_RS00920 55f59f18216552d9fdd06684250b2c45 409 SUPERFAMILY SSF50249 202 285 2.98E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDW54_RS00920 55f59f18216552d9fdd06684250b2c45 409 SUPERFAMILY SSF50249 103 188 6.39E-17 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDW54_RS00920 55f59f18216552d9fdd06684250b2c45 409 Gene3D G3DSA:2.40.50.140 107 191 2.7E-13 T 28-03-2018 CDW54_RS00920 55f59f18216552d9fdd06684250b2c45 409 SUPERFAMILY SSF50249 11 125 9.53E-21 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDW54_RS00920 55f59f18216552d9fdd06684250b2c45 409 SUPERFAMILY SSF50249 272 369 2.14E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDW54_RS00920 55f59f18216552d9fdd06684250b2c45 409 PRINTS PR00681 Ribosomal protein S1 signature 97 116 7.6E-47 T 28-03-2018 CDW54_RS00920 55f59f18216552d9fdd06684250b2c45 409 PRINTS PR00681 Ribosomal protein S1 signature 121 137 7.6E-47 T 28-03-2018 CDW54_RS00920 55f59f18216552d9fdd06684250b2c45 409 PRINTS PR00681 Ribosomal protein S1 signature 302 321 7.6E-47 T 28-03-2018 CDW54_RS00920 55f59f18216552d9fdd06684250b2c45 409 PRINTS PR00681 Ribosomal protein S1 signature 167 187 7.6E-47 T 28-03-2018 CDW54_RS00920 55f59f18216552d9fdd06684250b2c45 409 PRINTS PR00681 Ribosomal protein S1 signature 27 45 7.6E-47 T 28-03-2018 CDW54_RS00920 55f59f18216552d9fdd06684250b2c45 409 PRINTS PR00681 Ribosomal protein S1 signature 224 245 7.6E-47 T 28-03-2018 CDW54_RS00920 55f59f18216552d9fdd06684250b2c45 409 PRINTS PR00681 Ribosomal protein S1 signature 138 155 7.6E-47 T 28-03-2018 CDW54_RS00920 55f59f18216552d9fdd06684250b2c45 409 PRINTS PR00681 Ribosomal protein S1 signature 341 359 7.6E-47 T 28-03-2018 CDW54_RS11200 80bcd0dc5e02f4a79d34fcd85637a410 476 Gene3D G3DSA:1.10.10.410 413 474 2.1E-22 T 28-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal CDW54_RS11200 80bcd0dc5e02f4a79d34fcd85637a410 476 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 2 474 38.487 T 28-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 CDW54_RS11200 80bcd0dc5e02f4a79d34fcd85637a410 476 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 142 156 - T 28-03-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 CDW54_RS11200 80bcd0dc5e02f4a79d34fcd85637a410 476 SMART SM00845 326 473 1.5E-80 T 28-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 CDW54_RS11200 80bcd0dc5e02f4a79d34fcd85637a410 476 SUPERFAMILY SSF55931 4 294 1.44E-120 T 28-03-2018 CDW54_RS11200 80bcd0dc5e02f4a79d34fcd85637a410 476 SUPERFAMILY SSF89095 295 400 4.32E-36 T 28-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 CDW54_RS11200 80bcd0dc5e02f4a79d34fcd85637a410 476 Pfam PF02934 GatB/GatE catalytic domain 5 287 5.1E-111 T 28-03-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 CDW54_RS11200 80bcd0dc5e02f4a79d34fcd85637a410 476 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 1 473 5.2E-177 T 28-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 CDW54_RS11200 80bcd0dc5e02f4a79d34fcd85637a410 476 Pfam PF02637 GatB domain 326 473 1.1E-55 T 28-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 CDW54_RS06900 5dfa2bceb2f44a7472670da5b16d2166 503 TIGRFAM TIGR00910 2A0307_GadC: glutamate:gamma-aminobutyrate antiporter 1 498 5.7E-277 T 28-03-2018 IPR004759 Glutamate:g-aminobutyrate antiporter GO:0006865|GO:0016021 CDW54_RS06900 5dfa2bceb2f44a7472670da5b16d2166 503 Pfam PF13520 Amino acid permease 6 445 5.9E-61 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CDW54_RS06900 5dfa2bceb2f44a7472670da5b16d2166 503 PIRSF PIRSF006060 1 480 1.1E-56 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CDW54_RS11875 0ed93c029e583286d21cb68b7c4604be 152 Pfam PF04266 ASCH domain 35 151 1.5E-23 T 28-03-2018 IPR007374 ASCH domain CDW54_RS11875 0ed93c029e583286d21cb68b7c4604be 152 Gene3D G3DSA:3.10.400.10 3 151 3.0E-52 T 28-03-2018 CDW54_RS11875 0ed93c029e583286d21cb68b7c4604be 152 SUPERFAMILY SSF88697 1 151 1.44E-49 T 28-03-2018 IPR015947 PUA-like domain CDW54_RS11875 0ed93c029e583286d21cb68b7c4604be 152 PIRSF PIRSF021320 1 151 6.2E-50 T 28-03-2018 IPR009326 Protein of unknown function DUF984 CDW54_RS11875 0ed93c029e583286d21cb68b7c4604be 152 SMART SM01022 27 151 9.0E-42 T 28-03-2018 IPR007374 ASCH domain CDW54_RS02145 6c5d1a565df6111639ff1aa4830519c4 149 Pfam PF01029 NusB family 9 143 9.5E-38 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CDW54_RS02145 6c5d1a565df6111639ff1aa4830519c4 149 Gene3D G3DSA:1.10.940.10 2 149 3.0E-42 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CDW54_RS02145 6c5d1a565df6111639ff1aa4830519c4 149 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 5 146 22.7 T 28-03-2018 IPR011605 NusB antitermination factor GO:0006353 CDW54_RS02145 6c5d1a565df6111639ff1aa4830519c4 149 SUPERFAMILY SSF48013 6 141 5.1E-37 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CDW54_RS02145 6c5d1a565df6111639ff1aa4830519c4 149 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 7 144 1.3E-40 T 28-03-2018 IPR011605 NusB antitermination factor GO:0006353 CDW54_RS01045 ba2c00920e9362b08d2c9d1d67a062a0 395 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CDW54_RS01045 ba2c00920e9362b08d2c9d1d67a062a0 395 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 148 6.4E-16 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CDW54_RS01045 ba2c00920e9362b08d2c9d1d67a062a0 395 Pfam PF03144 Elongation factor Tu domain 2 225 294 6.5E-16 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CDW54_RS01045 ba2c00920e9362b08d2c9d1d67a062a0 395 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 393 3.2E-225 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CDW54_RS01045 ba2c00920e9362b08d2c9d1d67a062a0 395 Pfam PF00009 Elongation factor Tu GTP binding domain 10 201 5.6E-61 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDW54_RS01045 ba2c00920e9362b08d2c9d1d67a062a0 395 Gene3D G3DSA:3.40.50.300 1 74 1.3E-10 T 28-03-2018 CDW54_RS01045 ba2c00920e9362b08d2c9d1d67a062a0 395 Pfam PF03143 Elongation factor Tu C-terminal domain 299 393 6.2E-33 T 28-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal CDW54_RS01045 ba2c00920e9362b08d2c9d1d67a062a0 395 Gene3D G3DSA:2.40.30.10 301 393 2.9E-32 T 28-03-2018 CDW54_RS01045 ba2c00920e9362b08d2c9d1d67a062a0 395 PRINTS PR00315 GTP-binding elongation factor signature 94 105 1.4E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDW54_RS01045 ba2c00920e9362b08d2c9d1d67a062a0 395 PRINTS PR00315 GTP-binding elongation factor signature 78 88 1.4E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDW54_RS01045 ba2c00920e9362b08d2c9d1d67a062a0 395 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.4E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDW54_RS01045 ba2c00920e9362b08d2c9d1d67a062a0 395 PRINTS PR00315 GTP-binding elongation factor signature 131 140 1.4E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDW54_RS01045 ba2c00920e9362b08d2c9d1d67a062a0 395 PRINTS PR00315 GTP-binding elongation factor signature 14 27 1.4E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDW54_RS01045 ba2c00920e9362b08d2c9d1d67a062a0 395 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 395 59.92 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CDW54_RS01045 ba2c00920e9362b08d2c9d1d67a062a0 395 Gene3D G3DSA:2.40.30.10 191 299 1.5E-30 T 28-03-2018 CDW54_RS01045 ba2c00920e9362b08d2c9d1d67a062a0 395 Gene3D G3DSA:3.40.50.300 75 190 2.7E-33 T 28-03-2018 CDW54_RS01045 ba2c00920e9362b08d2c9d1d67a062a0 395 SUPERFAMILY SSF50447 205 302 3.33E-30 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CDW54_RS01045 ba2c00920e9362b08d2c9d1d67a062a0 395 SUPERFAMILY SSF52540 9 226 6.04E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS01045 ba2c00920e9362b08d2c9d1d67a062a0 395 SUPERFAMILY SSF50465 303 394 5.76E-36 T 28-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CDW54_RS07880 7623a368cbfa58c6d29ddc9af8a4d451 305 SUPERFAMILY SSF53686 2 302 5.89E-85 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CDW54_RS07880 7623a368cbfa58c6d29ddc9af8a4d451 305 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 6 293 1.2E-61 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CDW54_RS07880 7623a368cbfa58c6d29ddc9af8a4d451 305 Gene3D G3DSA:3.40.50.1100 42 140 4.3E-27 T 28-03-2018 CDW54_RS07880 7623a368cbfa58c6d29ddc9af8a4d451 305 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 34 52 - T 28-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 CDW54_RS07880 7623a368cbfa58c6d29ddc9af8a4d451 305 Gene3D G3DSA:3.40.50.1100 141 305 3.5E-49 T 28-03-2018 CDW54_RS02720 058dcae8541c79b709779963eb1f859f 320 Gene3D G3DSA:3.40.50.2300 195 315 8.3E-19 T 28-03-2018 CDW54_RS02720 058dcae8541c79b709779963eb1f859f 320 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 28-03-2018 CDW54_RS02720 058dcae8541c79b709779963eb1f859f 320 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 49 1.8E-21 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS02720 058dcae8541c79b709779963eb1f859f 320 SUPERFAMILY SSF53822 62 313 1.72E-59 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CDW54_RS02720 058dcae8541c79b709779963eb1f859f 320 Gene3D G3DSA:1.10.260.40 4 53 3.2E-21 T 28-03-2018 CDW54_RS02720 058dcae8541c79b709779963eb1f859f 320 Gene3D G3DSA:3.40.50.2300 54 168 1.5E-26 T 28-03-2018 CDW54_RS02720 058dcae8541c79b709779963eb1f859f 320 SUPERFAMILY SSF47413 3 57 9.48E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDW54_RS02720 058dcae8541c79b709779963eb1f859f 320 Gene3D G3DSA:3.40.50.2300 169 194 0.0018 T 28-03-2018 CDW54_RS02720 058dcae8541c79b709779963eb1f859f 320 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 5.6E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS02720 058dcae8541c79b709779963eb1f859f 320 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 5.6E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS02720 058dcae8541c79b709779963eb1f859f 320 Pfam PF13377 Periplasmic binding protein-like domain 167 310 2.6E-19 T 28-03-2018 CDW54_RS02720 058dcae8541c79b709779963eb1f859f 320 SMART SM00354 2 72 6.9E-38 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS12130 2b58f9e8d459b1eabf8997d770317dd2 742 SUPERFAMILY SSF52540 160 302 5.94E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS12130 2b58f9e8d459b1eabf8997d770317dd2 742 SUPERFAMILY SSF52540 50 103 5.94E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS12130 2b58f9e8d459b1eabf8997d770317dd2 742 SMART SM00327 557 739 3.2E-5 T 28-03-2018 IPR002035 von Willebrand factor, type A CDW54_RS12130 2b58f9e8d459b1eabf8997d770317dd2 742 Gene3D G3DSA:3.40.50.410 542 741 7.7E-16 T 28-03-2018 IPR002035 von Willebrand factor, type A CDW54_RS12130 2b58f9e8d459b1eabf8997d770317dd2 742 Gene3D G3DSA:3.40.50.300 25 247 3.5E-19 T 28-03-2018 CDW54_RS12130 2b58f9e8d459b1eabf8997d770317dd2 742 SUPERFAMILY SSF53300 556 740 1.56E-14 T 28-03-2018 IPR002035 von Willebrand factor, type A CDW54_RS12130 2b58f9e8d459b1eabf8997d770317dd2 742 Pfam PF00092 von Willebrand factor type A domain 563 728 5.9E-7 T 28-03-2018 IPR002035 von Willebrand factor, type A CDW54_RS12130 2b58f9e8d459b1eabf8997d770317dd2 742 Pfam PF07728 AAA domain (dynein-related subfamily) 53 114 3.2E-6 T 28-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 CDW54_RS12130 2b58f9e8d459b1eabf8997d770317dd2 742 Pfam PF07728 AAA domain (dynein-related subfamily) 124 241 5.2E-5 T 28-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 CDW54_RS08705 a3035db96a4edba33230cd7f4a7abf53 303 SUPERFAMILY SSF54534 140 235 2.35E-13 T 28-03-2018 CDW54_RS08705 a3035db96a4edba33230cd7f4a7abf53 303 Gene3D G3DSA:3.10.50.40 125 261 5.0E-17 T 28-03-2018 CDW54_RS08705 a3035db96a4edba33230cd7f4a7abf53 303 SUPERFAMILY SSF109998 26 169 1.53E-18 T 28-03-2018 IPR027304 Trigger factor/SurA domain CDW54_RS08705 a3035db96a4edba33230cd7f4a7abf53 303 Gene3D G3DSA:1.10.4030.10 20 124 7.6E-9 T 28-03-2018 CDW54_RS08705 a3035db96a4edba33230cd7f4a7abf53 303 Pfam PF13145 PPIC-type PPIASE domain 127 236 4.2E-11 T 28-03-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 CDW54_RS08705 a3035db96a4edba33230cd7f4a7abf53 303 Hamap MF_01145 Foldase protein PrsA [prsA]. 2 294 20.586 T 28-03-2018 IPR023059 Foldase protein PrsA GO:0003755 CDW54_RS03825 07f4c36038e849f57229a1a626eadaee 122 Gene3D G3DSA:1.20.5.710 3 51 1.5E-16 T 28-03-2018 CDW54_RS03825 07f4c36038e849f57229a1a626eadaee 122 SUPERFAMILY SSF54736 51 122 5.93E-24 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CDW54_RS03825 07f4c36038e849f57229a1a626eadaee 122 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 122 3.1E-48 T 28-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS03825 07f4c36038e849f57229a1a626eadaee 122 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 56 122 1.4E-29 T 28-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS03825 07f4c36038e849f57229a1a626eadaee 122 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 2 122 24.5 T 28-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS03825 07f4c36038e849f57229a1a626eadaee 122 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 58 100 2.0E-15 T 28-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS03825 07f4c36038e849f57229a1a626eadaee 122 SUPERFAMILY SSF48300 4 58 1.44E-15 T 28-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS03825 07f4c36038e849f57229a1a626eadaee 122 Gene3D G3DSA:3.30.1390.10 52 122 3.8E-30 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CDW54_RS03825 07f4c36038e849f57229a1a626eadaee 122 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 5 50 5.7E-19 T 28-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS10785 0a590393c2655e26177e035418885534 339 SUPERFAMILY SSF53671 6 333 3.37E-99 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CDW54_RS10785 0a590393c2655e26177e035418885534 339 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 54 61 - T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CDW54_RS10785 0a590393c2655e26177e035418885534 339 Gene3D G3DSA:3.40.50.1370 7 162 6.6E-56 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CDW54_RS10785 0a590393c2655e26177e035418885534 339 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 9 149 1.9E-44 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CDW54_RS10785 0a590393c2655e26177e035418885534 339 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 8 332 80.562 T 28-03-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 CDW54_RS10785 0a590393c2655e26177e035418885534 339 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 9 331 2.4E-123 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CDW54_RS10785 0a590393c2655e26177e035418885534 339 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 296 319 2.8E-22 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CDW54_RS10785 0a590393c2655e26177e035418885534 339 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 267 276 2.8E-22 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CDW54_RS10785 0a590393c2655e26177e035418885534 339 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 136 147 2.8E-22 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CDW54_RS10785 0a590393c2655e26177e035418885534 339 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 54 73 2.8E-22 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CDW54_RS10785 0a590393c2655e26177e035418885534 339 PRINTS PR00102 Ornithine carbamoyltransferase signature 310 321 2.4E-27 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CDW54_RS10785 0a590393c2655e26177e035418885534 339 PRINTS PR00102 Ornithine carbamoyltransferase signature 85 98 2.4E-27 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CDW54_RS10785 0a590393c2655e26177e035418885534 339 PRINTS PR00102 Ornithine carbamoyltransferase signature 229 239 2.4E-27 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CDW54_RS10785 0a590393c2655e26177e035418885534 339 PRINTS PR00102 Ornithine carbamoyltransferase signature 52 66 2.4E-27 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CDW54_RS10785 0a590393c2655e26177e035418885534 339 PRINTS PR00102 Ornithine carbamoyltransferase signature 125 139 2.4E-27 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CDW54_RS10785 0a590393c2655e26177e035418885534 339 Gene3D G3DSA:3.40.50.1370 163 333 1.3E-50 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CDW54_RS10785 0a590393c2655e26177e035418885534 339 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 155 329 4.1E-54 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CDW54_RS10905 7a4ada2382c0efad9e93dc0bb982717d 307 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 1 217 5.6E-72 T 28-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDW54_RS10905 7a4ada2382c0efad9e93dc0bb982717d 307 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 1 303 17.956 T 28-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDW54_RS10905 7a4ada2382c0efad9e93dc0bb982717d 307 Gene3D G3DSA:3.30.2350.10 1 228 1.2E-76 T 28-03-2018 CDW54_RS10905 7a4ada2382c0efad9e93dc0bb982717d 307 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 23 179 1.2E-53 T 28-03-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 CDW54_RS10905 7a4ada2382c0efad9e93dc0bb982717d 307 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 180 238 5.3E-14 T 28-03-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 CDW54_RS10905 7a4ada2382c0efad9e93dc0bb982717d 307 SUPERFAMILY SSF55120 1 236 1.01E-75 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDW54_RS09210 c19b05f332abcc79b30fa0df2f721640 644 SMART SM00382 28 245 1.2E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS09210 c19b05f332abcc79b30fa0df2f721640 644 SMART SM00382 353 520 6.4E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS09210 c19b05f332abcc79b30fa0df2f721640 644 Pfam PF12848 ABC transporter 232 315 1.2E-25 T 28-03-2018 IPR032781 ABC-transporter extension domain CDW54_RS09210 c19b05f332abcc79b30fa0df2f721640 644 SUPERFAMILY SSF52540 6 246 2.08E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS09210 c19b05f332abcc79b30fa0df2f721640 644 Gene3D G3DSA:3.40.50.300 293 554 7.2E-50 T 28-03-2018 CDW54_RS09210 c19b05f332abcc79b30fa0df2f721640 644 ProSitePatterns PS00211 ABC transporters family signature. 446 460 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS09210 c19b05f332abcc79b30fa0df2f721640 644 Gene3D G3DSA:3.40.50.300 4 292 8.4E-55 T 28-03-2018 CDW54_RS09210 c19b05f332abcc79b30fa0df2f721640 644 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS09210 c19b05f332abcc79b30fa0df2f721640 644 SUPERFAMILY SSF52540 310 535 2.28E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS09210 c19b05f332abcc79b30fa0df2f721640 644 Pfam PF00005 ABC transporter 20 193 1.3E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS09210 c19b05f332abcc79b30fa0df2f721640 644 Pfam PF00005 ABC transporter 346 474 7.1E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS09210 c19b05f332abcc79b30fa0df2f721640 644 Pfam PF16326 ABC transporter C-terminal domain 569 636 3.0E-9 T 28-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 CDW54_RS03950 2ddbe51f20a0a91b989b4826c451abce 453 Gene3D G3DSA:1.25.60.10 1 127 2.1E-25 T 28-03-2018 CDW54_RS03950 2ddbe51f20a0a91b989b4826c451abce 453 SUPERFAMILY SSF158791 8 135 2.22E-29 T 28-03-2018 CDW54_RS03950 2ddbe51f20a0a91b989b4826c451abce 453 SMART SM00924 33 138 3.5E-24 T 28-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain CDW54_RS03950 2ddbe51f20a0a91b989b4826c451abce 453 Pfam PF03448 MgtE intracellular N domain 33 136 1.2E-21 T 28-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain CDW54_RS03950 2ddbe51f20a0a91b989b4826c451abce 453 SUPERFAMILY SSF161093 278 449 1.44E-46 T 28-03-2018 CDW54_RS03950 2ddbe51f20a0a91b989b4826c451abce 453 Gene3D G3DSA:3.10.580.10 128 267 4.7E-23 T 28-03-2018 CDW54_RS03950 2ddbe51f20a0a91b989b4826c451abce 453 Gene3D G3DSA:1.10.357.20 278 452 2.8E-36 T 28-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 CDW54_RS03950 2ddbe51f20a0a91b989b4826c451abce 453 SMART SM00116 209 257 7.7E-7 T 28-03-2018 IPR000644 CBS domain CDW54_RS03950 2ddbe51f20a0a91b989b4826c451abce 453 SMART SM00116 145 198 0.0014 T 28-03-2018 IPR000644 CBS domain CDW54_RS03950 2ddbe51f20a0a91b989b4826c451abce 453 SUPERFAMILY SSF54631 137 270 1.39E-31 T 28-03-2018 CDW54_RS03950 2ddbe51f20a0a91b989b4826c451abce 453 Pfam PF01769 Divalent cation transporter 322 442 2.3E-27 T 28-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 CDW54_RS03950 2ddbe51f20a0a91b989b4826c451abce 453 Pfam PF00571 CBS domain 138 194 3.3E-8 T 28-03-2018 IPR000644 CBS domain CDW54_RS03950 2ddbe51f20a0a91b989b4826c451abce 453 Pfam PF00571 CBS domain 202 257 1.2E-9 T 28-03-2018 IPR000644 CBS domain CDW54_RS03950 2ddbe51f20a0a91b989b4826c451abce 453 TIGRFAM TIGR00400 mgtE: magnesium transporter 13 450 3.1E-117 T 28-03-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 CDW54_RS10545 72ecc7fd07c26b7c2ccfcc1a97f930ba 169 Gene3D G3DSA:3.40.50.300 19 165 6.9E-7 T 28-03-2018 CDW54_RS10545 72ecc7fd07c26b7c2ccfcc1a97f930ba 169 SUPERFAMILY SSF52540 38 158 1.25E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS12000 abafc02dbdb9a2dafcfa82449c5eb1ec 283 SUPERFAMILY SSF161098 12 283 1.23E-61 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS12000 abafc02dbdb9a2dafcfa82449c5eb1ec 283 Gene3D G3DSA:1.10.3720.10 4 270 3.8E-38 T 28-03-2018 CDW54_RS12000 abafc02dbdb9a2dafcfa82449c5eb1ec 283 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 274 2.1E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS07665 374b2bf4dcbc58a2d9f28978ce4b60fd 293 Pfam PF03466 LysR substrate binding domain 93 290 5.5E-27 T 28-03-2018 IPR005119 LysR, substrate-binding CDW54_RS07665 374b2bf4dcbc58a2d9f28978ce4b60fd 293 Gene3D G3DSA:1.10.10.10 1 83 1.9E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS07665 374b2bf4dcbc58a2d9f28978ce4b60fd 293 SUPERFAMILY SSF53850 92 290 6.05E-24 T 28-03-2018 CDW54_RS07665 374b2bf4dcbc58a2d9f28978ce4b60fd 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 1.9E-15 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDW54_RS07665 374b2bf4dcbc58a2d9f28978ce4b60fd 293 Gene3D G3DSA:3.40.190.10 182 264 1.1E-21 T 28-03-2018 CDW54_RS07665 374b2bf4dcbc58a2d9f28978ce4b60fd 293 Gene3D G3DSA:3.40.190.10 92 181 5.6E-10 T 28-03-2018 CDW54_RS07665 374b2bf4dcbc58a2d9f28978ce4b60fd 293 SUPERFAMILY SSF46785 1 85 1.31E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS04490 f6fb39cc6f412e17270b80f1df85127e 108 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 13 105 8.6E-33 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CDW54_RS04490 f6fb39cc6f412e17270b80f1df85127e 108 SUPERFAMILY SSF46973 6 106 8.89E-33 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CDW54_RS04490 f6fb39cc6f412e17270b80f1df85127e 108 PIRSF PIRSF000699 3 108 1.8E-34 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CDW54_RS04490 f6fb39cc6f412e17270b80f1df85127e 108 Gene3D G3DSA:1.20.58.80 8 106 6.3E-33 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CDW54_RS00625 94329264cadc6c3142199667a15c7f26 440 PIRSF PIRSF000350 1 439 1.2E-67 T 28-03-2018 CDW54_RS00625 94329264cadc6c3142199667a15c7f26 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 250 264 2.1E-50 T 28-03-2018 CDW54_RS00625 94329264cadc6c3142199667a15c7f26 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 166 191 2.1E-50 T 28-03-2018 CDW54_RS00625 94329264cadc6c3142199667a15c7f26 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 37 52 2.1E-50 T 28-03-2018 CDW54_RS00625 94329264cadc6c3142199667a15c7f26 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 413 433 2.1E-50 T 28-03-2018 CDW54_RS00625 94329264cadc6c3142199667a15c7f26 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 2.1E-50 T 28-03-2018 CDW54_RS00625 94329264cadc6c3142199667a15c7f26 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 132 141 2.1E-50 T 28-03-2018 CDW54_RS00625 94329264cadc6c3142199667a15c7f26 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 330 351 2.1E-50 T 28-03-2018 CDW54_RS00625 94329264cadc6c3142199667a15c7f26 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 391 406 2.1E-50 T 28-03-2018 CDW54_RS00625 94329264cadc6c3142199667a15c7f26 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 292 299 2.1E-50 T 28-03-2018 CDW54_RS00625 94329264cadc6c3142199667a15c7f26 440 SUPERFAMILY SSF55424 331 437 1.03E-18 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CDW54_RS00625 94329264cadc6c3142199667a15c7f26 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 249 265 5.3E-28 T 28-03-2018 CDW54_RS00625 94329264cadc6c3142199667a15c7f26 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 277 299 5.3E-28 T 28-03-2018 CDW54_RS00625 94329264cadc6c3142199667a15c7f26 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 166 184 5.3E-28 T 28-03-2018 CDW54_RS00625 94329264cadc6c3142199667a15c7f26 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 129 147 5.3E-28 T 28-03-2018 CDW54_RS00625 94329264cadc6c3142199667a15c7f26 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 5.3E-28 T 28-03-2018 CDW54_RS00625 94329264cadc6c3142199667a15c7f26 440 Gene3D G3DSA:3.50.50.60 1 159 2.3E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS00625 94329264cadc6c3142199667a15c7f26 440 SUPERFAMILY SSF51905 1 323 1.18E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS00625 94329264cadc6c3142199667a15c7f26 440 Gene3D G3DSA:3.40.50.720 160 326 6.4E-30 T 28-03-2018 CDW54_RS00625 94329264cadc6c3142199667a15c7f26 440 Gene3D G3DSA:3.30.390.30 327 440 2.0E-16 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CDW54_RS00625 94329264cadc6c3142199667a15c7f26 440 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 334 433 8.3E-11 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CDW54_RS00625 94329264cadc6c3142199667a15c7f26 440 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 314 3.3E-55 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS10450 08c87277f33070bd0d1d2966647872a6 298 Gene3D G3DSA:1.10.3720.10 68 298 2.2E-54 T 28-03-2018 CDW54_RS10450 08c87277f33070bd0d1d2966647872a6 298 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 287 4.7E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS10450 08c87277f33070bd0d1d2966647872a6 298 SUPERFAMILY SSF161098 62 288 2.22E-70 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS10450 08c87277f33070bd0d1d2966647872a6 298 Gene3D G3DSA:1.20.58.370 8 52 1.8E-7 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CDW54_RS03210 76ee482342b564866a9ae863f12359aa 356 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 317 1.8E-20 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CDW54_RS03210 76ee482342b564866a9ae863f12359aa 356 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS03210 76ee482342b564866a9ae863f12359aa 356 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 296 2.3E-14 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CDW54_RS03210 76ee482342b564866a9ae863f12359aa 356 SMART SM00382 33 240 1.3E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS03210 76ee482342b564866a9ae863f12359aa 356 SUPERFAMILY SSF52540 32 312 4.95E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS03210 76ee482342b564866a9ae863f12359aa 356 Gene3D G3DSA:3.40.50.300 1 332 1.1E-81 T 28-03-2018 CDW54_RS03210 76ee482342b564866a9ae863f12359aa 356 Pfam PF00005 ABC transporter 25 182 1.6E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS07405 43e6c27f5eaa678fe7af05d6276bb73e 184 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 55 77 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CDW54_RS07405 43e6c27f5eaa678fe7af05d6276bb73e 184 Pfam PF01066 CDP-alcohol phosphatidyltransferase 14 77 2.6E-16 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CDW54_RS07405 43e6c27f5eaa678fe7af05d6276bb73e 184 PIRSF PIRSF000847 9 184 1.7E-37 T 28-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CDW54_RS10770 18c5babab6d7048a7d14e34e59f55236 338 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 6 318 1.8E-133 T 28-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CDW54_RS10770 18c5babab6d7048a7d14e34e59f55236 338 Gene3D G3DSA:3.30.420.40 4 146 1.5E-43 T 28-03-2018 CDW54_RS10770 18c5babab6d7048a7d14e34e59f55236 338 SUPERFAMILY SSF53067 5 125 5.24E-31 T 28-03-2018 CDW54_RS10770 18c5babab6d7048a7d14e34e59f55236 338 SUPERFAMILY SSF53067 104 312 5.57E-44 T 28-03-2018 CDW54_RS10770 18c5babab6d7048a7d14e34e59f55236 338 Pfam PF00814 Glycoprotease family 26 311 5.0E-106 T 28-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CDW54_RS10770 18c5babab6d7048a7d14e34e59f55236 338 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 4 338 61.951 T 28-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CDW54_RS10770 18c5babab6d7048a7d14e34e59f55236 338 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 7 311 1.3E-108 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CDW54_RS10770 18c5babab6d7048a7d14e34e59f55236 338 ProSitePatterns PS01016 Glycoprotease family signature. 99 119 - T 28-03-2018 IPR017860 Peptidase M22, conserved site KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618|Reactome: R-HSA-6782315 CDW54_RS10770 18c5babab6d7048a7d14e34e59f55236 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 156 177 1.7E-48 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CDW54_RS10770 18c5babab6d7048a7d14e34e59f55236 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 266 275 1.7E-48 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CDW54_RS10770 18c5babab6d7048a7d14e34e59f55236 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 7 20 1.7E-48 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CDW54_RS10770 18c5babab6d7048a7d14e34e59f55236 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 100 119 1.7E-48 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CDW54_RS10770 18c5babab6d7048a7d14e34e59f55236 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 133 145 1.7E-48 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CDW54_RS10770 18c5babab6d7048a7d14e34e59f55236 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 79 99 1.7E-48 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CDW54_RS10770 18c5babab6d7048a7d14e34e59f55236 338 Gene3D G3DSA:3.30.420.40 147 292 3.9E-19 T 28-03-2018 CDW54_RS12140 cd1004cca656371e783ed44f1aa7604b 181 SUPERFAMILY SSF110710 6 181 7.06E-77 T 28-03-2018 CDW54_RS12140 cd1004cca656371e783ed44f1aa7604b 181 ProDom PD102102 UPF0340 3D-STRUCTURE YWLG SMU.87 STU1894 BT9727_4999 TRANSFERASE TTE0860 SPY1898/M5005_SPY1614 TT1679 28 181 2.0E-86 T 28-03-2018 IPR006340 Protein of unknown function DUF436 CDW54_RS12140 cd1004cca656371e783ed44f1aa7604b 181 Hamap MF_00800 UPF0340 protein . 1 181 90.505 T 28-03-2018 IPR006340 Protein of unknown function DUF436 CDW54_RS12140 cd1004cca656371e783ed44f1aa7604b 181 PIRSF PIRSF007510 3 181 5.3E-83 T 28-03-2018 IPR006340 Protein of unknown function DUF436 CDW54_RS12140 cd1004cca656371e783ed44f1aa7604b 181 Pfam PF04260 Protein of unknown function (DUF436) 11 181 3.3E-75 T 28-03-2018 IPR006340 Protein of unknown function DUF436 CDW54_RS12140 cd1004cca656371e783ed44f1aa7604b 181 TIGRFAM TIGR01440 TIGR01440: TIGR01440 family protein 11 181 9.4E-84 T 28-03-2018 IPR006340 Protein of unknown function DUF436 CDW54_RS12140 cd1004cca656371e783ed44f1aa7604b 181 Gene3D G3DSA:3.40.50.10360 7 181 2.3E-78 T 28-03-2018 IPR006340 Protein of unknown function DUF436 CDW54_RS03010 f88f6c35b0931de250ee1752c0426e24 226 Hamap MF_00457 UPF0173 metal-dependent hydrolase . 1 226 36.58 T 28-03-2018 IPR022877 Protein of unknown funcion UPF0173 CDW54_RS03010 f88f6c35b0931de250ee1752c0426e24 226 SUPERFAMILY SSF56281 1 213 4.32E-37 T 28-03-2018 IPR001279 Metallo-beta-lactamase CDW54_RS03010 f88f6c35b0931de250ee1752c0426e24 226 SMART SM00849 7 192 4.7E-9 T 28-03-2018 IPR001279 Metallo-beta-lactamase CDW54_RS03010 f88f6c35b0931de250ee1752c0426e24 226 Pfam PF13483 Beta-lactamase superfamily domain 2 192 4.5E-27 T 28-03-2018 CDW54_RS03010 f88f6c35b0931de250ee1752c0426e24 226 Gene3D G3DSA:3.60.15.10 1 223 1.5E-34 T 28-03-2018 IPR001279 Metallo-beta-lactamase CDW54_RS05940 cfcb469d3281a8fb32f7025d85d99149 92 SUPERFAMILY SSF54570 3 84 1.26E-34 T 28-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS05940 cfcb469d3281a8fb32f7025d85d99149 92 PIRSF PIRSF002144 1 92 1.7E-31 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS05940 cfcb469d3281a8fb32f7025d85d99149 92 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 2.8E-23 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS05940 cfcb469d3281a8fb32f7025d85d99149 92 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 2.8E-23 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS05940 cfcb469d3281a8fb32f7025d85d99149 92 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 2.8E-23 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS05940 cfcb469d3281a8fb32f7025d85d99149 92 Pfam PF00203 Ribosomal protein S19 3 83 4.1E-36 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS05940 cfcb469d3281a8fb32f7025d85d99149 92 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 3.3E-46 T 28-03-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 CDW54_RS05940 cfcb469d3281a8fb32f7025d85d99149 92 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 28-03-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS05940 cfcb469d3281a8fb32f7025d85d99149 92 Gene3D G3DSA:3.30.860.10 1 92 2.2E-39 T 28-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS05940 cfcb469d3281a8fb32f7025d85d99149 92 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.221 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS00245 fff31d0edd04dd34c77663f66372bdb4 163 Gene3D G3DSA:3.40.50.620 1 158 1.5E-34 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDW54_RS00245 fff31d0edd04dd34c77663f66372bdb4 163 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 2 159 33.296 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CDW54_RS00245 fff31d0edd04dd34c77663f66372bdb4 163 SUPERFAMILY SSF52374 2 156 5.9E-43 T 28-03-2018 CDW54_RS00245 fff31d0edd04dd34c77663f66372bdb4 163 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 11 73 2.0E-7 T 28-03-2018 CDW54_RS00245 fff31d0edd04dd34c77663f66372bdb4 163 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 63 7.5E-19 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CDW54_RS00245 fff31d0edd04dd34c77663f66372bdb4 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 2 20 3.8E-43 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CDW54_RS00245 fff31d0edd04dd34c77663f66372bdb4 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 20 41 3.8E-43 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CDW54_RS00245 fff31d0edd04dd34c77663f66372bdb4 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 113 135 3.8E-43 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CDW54_RS00245 fff31d0edd04dd34c77663f66372bdb4 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 49 73 3.8E-43 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CDW54_RS00245 fff31d0edd04dd34c77663f66372bdb4 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 86 102 3.8E-43 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CDW54_RS00245 fff31d0edd04dd34c77663f66372bdb4 163 Pfam PF01467 Cytidylyltransferase-like 5 134 6.1E-20 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CDW54_RS00245 fff31d0edd04dd34c77663f66372bdb4 163 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 3 156 4.7E-61 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CDW54_RS03005 fe5dfdeceab05946b92a67d17e29325f 443 SMART SM00116 259 307 21.0 T 28-03-2018 IPR000644 CBS domain CDW54_RS03005 fe5dfdeceab05946b92a67d17e29325f 443 SMART SM00116 200 248 0.0058 T 28-03-2018 IPR000644 CBS domain CDW54_RS03005 fe5dfdeceab05946b92a67d17e29325f 443 Gene3D G3DSA:3.10.129.10 302 443 9.0E-17 T 28-03-2018 CDW54_RS03005 fe5dfdeceab05946b92a67d17e29325f 443 SUPERFAMILY SSF54631 182 307 2.4E-26 T 28-03-2018 CDW54_RS03005 fe5dfdeceab05946b92a67d17e29325f 443 Pfam PF07085 DRTGG domain 76 178 3.4E-29 T 28-03-2018 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CDW54_RS03005 fe5dfdeceab05946b92a67d17e29325f 443 Gene3D G3DSA:1.10.10.10 3 68 1.8E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS03005 fe5dfdeceab05946b92a67d17e29325f 443 Pfam PF00571 CBS domain 254 306 4.3E-5 T 28-03-2018 IPR000644 CBS domain CDW54_RS03005 fe5dfdeceab05946b92a67d17e29325f 443 Pfam PF00571 CBS domain 204 246 7.7E-5 T 28-03-2018 IPR000644 CBS domain CDW54_RS03005 fe5dfdeceab05946b92a67d17e29325f 443 Pfam PF03061 Thioesterase superfamily 378 427 1.1E-4 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CDW54_RS03005 fe5dfdeceab05946b92a67d17e29325f 443 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 58 4.1E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDW54_RS03005 fe5dfdeceab05946b92a67d17e29325f 443 SUPERFAMILY SSF46785 8 64 5.99E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS03005 fe5dfdeceab05946b92a67d17e29325f 443 SUPERFAMILY SSF54637 344 440 1.97E-12 T 28-03-2018 IPR029069 HotDog domain CDW54_RS03005 fe5dfdeceab05946b92a67d17e29325f 443 SUPERFAMILY SSF75138 72 185 2.49E-28 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CDW54_RS03005 fe5dfdeceab05946b92a67d17e29325f 443 Gene3D G3DSA:3.10.580.10 181 301 7.2E-22 T 28-03-2018 CDW54_RS03005 fe5dfdeceab05946b92a67d17e29325f 443 Gene3D G3DSA:3.40.1390.20 69 180 6.7E-24 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CDW54_RS10465 8feb6a2a4d5613d0f08b022026b6b98e 554 Gene3D G3DSA:3.40.50.970 1 187 3.2E-47 T 28-03-2018 CDW54_RS10465 8feb6a2a4d5613d0f08b022026b6b98e 554 SUPERFAMILY SSF52518 5 175 4.31E-49 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CDW54_RS10465 8feb6a2a4d5613d0f08b022026b6b98e 554 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 193 327 1.2E-26 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CDW54_RS10465 8feb6a2a4d5613d0f08b022026b6b98e 554 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 8 172 5.1E-49 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CDW54_RS10465 8feb6a2a4d5613d0f08b022026b6b98e 554 TIGRFAM TIGR02418 acolac_catab: acetolactate synthase, catabolic 10 545 3.8E-275 T 28-03-2018 IPR012782 Acetolactate synthase, catabolic GO:0000287|GO:0003984|GO:0030976|GO:0034077 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CDW54_RS10465 8feb6a2a4d5613d0f08b022026b6b98e 554 SUPERFAMILY SSF52467 186 351 4.8E-36 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CDW54_RS10465 8feb6a2a4d5613d0f08b022026b6b98e 554 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 425 444 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CDW54_RS10465 8feb6a2a4d5613d0f08b022026b6b98e 554 SUPERFAMILY SSF52518 364 543 1.39E-58 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CDW54_RS10465 8feb6a2a4d5613d0f08b022026b6b98e 554 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 388 534 2.9E-43 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CDW54_RS10465 8feb6a2a4d5613d0f08b022026b6b98e 554 Gene3D G3DSA:3.40.50.1220 188 347 8.7E-31 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CDW54_RS10465 8feb6a2a4d5613d0f08b022026b6b98e 554 Gene3D G3DSA:3.40.50.970 348 543 1.3E-40 T 28-03-2018 CDW54_RS00355 7f28afc7a0eb13c4838629fc6bc8a6a9 362 Gene3D G3DSA:3.40.50.2300 33 192 1.1E-28 T 28-03-2018 CDW54_RS00355 7f28afc7a0eb13c4838629fc6bc8a6a9 362 Gene3D G3DSA:3.40.50.2300 204 335 1.3E-12 T 28-03-2018 CDW54_RS00355 7f28afc7a0eb13c4838629fc6bc8a6a9 362 SUPERFAMILY SSF53822 36 347 1.36E-66 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CDW54_RS00355 7f28afc7a0eb13c4838629fc6bc8a6a9 362 Pfam PF13407 Periplasmic binding protein domain 37 314 4.1E-62 T 28-03-2018 IPR025997 Periplasmic binding protein CDW54_RS06750 185e9ce5854f2ab4db3422192e1b41aa 301 SUPERFAMILY SSF144083 238 298 1.57E-14 T 28-03-2018 CDW54_RS06750 185e9ce5854f2ab4db3422192e1b41aa 301 Gene3D G3DSA:3.30.460.20 4 115 2.3E-15 T 28-03-2018 CDW54_RS06750 185e9ce5854f2ab4db3422192e1b41aa 301 Gene3D G3DSA:1.20.58.340 236 300 5.0E-12 T 28-03-2018 CDW54_RS06750 185e9ce5854f2ab4db3422192e1b41aa 301 SUPERFAMILY SSF143865 6 237 7.85E-31 T 28-03-2018 CDW54_RS06750 185e9ce5854f2ab4db3422192e1b41aa 301 Gene3D G3DSA:1.20.58.340 117 235 1.3E-9 T 28-03-2018 CDW54_RS06750 185e9ce5854f2ab4db3422192e1b41aa 301 Pfam PF01544 CorA-like Mg2+ transporter protein 12 297 3.0E-61 T 28-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 CDW54_RS07060 ca6d79997a738a79808a4724e9a9dbfb 544 Pfam PF10131 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein 68 392 7.9E-12 T 28-03-2018 IPR018776 Membrane protein, 6-pyruvoyl-tetrahydropterin synthase-related domain CDW54_RS07385 b3924f14be35ca7f387cb8b504aaa3c1 498 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 6 495 5.5E-220 T 28-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CDW54_RS07385 b3924f14be35ca7f387cb8b504aaa3c1 498 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 363 383 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CDW54_RS07385 b3924f14be35ca7f387cb8b504aaa3c1 498 Gene3D G3DSA:3.30.420.40 250 498 1.9E-74 T 28-03-2018 CDW54_RS07385 b3924f14be35ca7f387cb8b504aaa3c1 498 SUPERFAMILY SSF53067 6 255 6.13E-94 T 28-03-2018 CDW54_RS07385 b3924f14be35ca7f387cb8b504aaa3c1 498 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 136 148 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CDW54_RS07385 b3924f14be35ca7f387cb8b504aaa3c1 498 Gene3D G3DSA:3.30.420.40 1 249 2.9E-86 T 28-03-2018 CDW54_RS07385 b3924f14be35ca7f387cb8b504aaa3c1 498 SUPERFAMILY SSF53067 255 495 1.24E-80 T 28-03-2018 CDW54_RS07385 b3924f14be35ca7f387cb8b504aaa3c1 498 PIRSF PIRSF000538 4 498 7.3E-168 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CDW54_RS07385 b3924f14be35ca7f387cb8b504aaa3c1 498 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 263 451 3.1E-58 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CDW54_RS07385 b3924f14be35ca7f387cb8b504aaa3c1 498 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 6 253 1.6E-86 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CDW54_RS07385 b3924f14be35ca7f387cb8b504aaa3c1 498 Hamap MF_00186 Glycerol kinase [glpK]. 4 498 56.439 T 28-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CDW54_RS07720 67fdb65b5099b1a245c795499d680931 716 Pfam PF00877 NlpC/P60 family 323 416 3.5E-25 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CDW54_RS07720 67fdb65b5099b1a245c795499d680931 716 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 468 607 1.9E-21 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CDW54_RS07720 67fdb65b5099b1a245c795499d680931 716 SMART SM00047 452 612 1.2E-44 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CDW54_RS07720 67fdb65b5099b1a245c795499d680931 716 Gene3D G3DSA:1.10.530.10 456 612 1.4E-38 T 28-03-2018 CDW54_RS07720 67fdb65b5099b1a245c795499d680931 716 Gene3D G3DSA:3.90.1720.10 304 426 1.1E-36 T 28-03-2018 CDW54_RS07720 67fdb65b5099b1a245c795499d680931 716 SUPERFAMILY SSF54001 303 421 3.92E-40 T 28-03-2018 CDW54_RS08775 75ca071f5922bc505144add6d1b6c9da 480 PRINTS PR00131 Glycosyl hydrolase family 1 signature 375 383 3.6E-18 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS08775 75ca071f5922bc505144add6d1b6c9da 480 PRINTS PR00131 Glycosyl hydrolase family 1 signature 396 407 3.6E-18 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS08775 75ca071f5922bc505144add6d1b6c9da 480 PRINTS PR00131 Glycosyl hydrolase family 1 signature 442 454 3.6E-18 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS08775 75ca071f5922bc505144add6d1b6c9da 480 PRINTS PR00131 Glycosyl hydrolase family 1 signature 417 434 3.6E-18 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS08775 75ca071f5922bc505144add6d1b6c9da 480 PRINTS PR00131 Glycosyl hydrolase family 1 signature 309 323 3.6E-18 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS08775 75ca071f5922bc505144add6d1b6c9da 480 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 9 23 - T 28-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site CDW54_RS08775 75ca071f5922bc505144add6d1b6c9da 480 SUPERFAMILY SSF51445 2 478 1.12E-156 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CDW54_RS08775 75ca071f5922bc505144add6d1b6c9da 480 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 375 383 - T 28-03-2018 IPR018120 Glycoside hydrolase family 1, active site CDW54_RS08775 75ca071f5922bc505144add6d1b6c9da 480 Gene3D G3DSA:3.20.20.80 2 480 5.7E-145 T 28-03-2018 CDW54_RS08775 75ca071f5922bc505144add6d1b6c9da 480 Pfam PF00232 Glycosyl hydrolase family 1 2 477 7.7E-131 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS12575 0c2fa89602445f12a5e48d7dfeee6409 450 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 331 429 7.0E-16 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CDW54_RS12575 0c2fa89602445f12a5e48d7dfeee6409 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 149 174 7.6E-15 T 28-03-2018 CDW54_RS12575 0c2fa89602445f12a5e48d7dfeee6409 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 236 250 7.6E-15 T 28-03-2018 CDW54_RS12575 0c2fa89602445f12a5e48d7dfeee6409 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 7.6E-15 T 28-03-2018 CDW54_RS12575 0c2fa89602445f12a5e48d7dfeee6409 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 276 283 7.6E-15 T 28-03-2018 CDW54_RS12575 0c2fa89602445f12a5e48d7dfeee6409 450 SUPERFAMILY SSF55424 322 445 8.93E-33 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CDW54_RS12575 0c2fa89602445f12a5e48d7dfeee6409 450 Gene3D G3DSA:3.50.50.60 1 114 1.4E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS12575 0c2fa89602445f12a5e48d7dfeee6409 450 Gene3D G3DSA:3.50.50.60 193 318 1.5E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS12575 0c2fa89602445f12a5e48d7dfeee6409 450 Gene3D G3DSA:3.30.390.30 334 446 1.0E-20 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CDW54_RS12575 0c2fa89602445f12a5e48d7dfeee6409 450 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 1 306 1.1E-68 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS12575 0c2fa89602445f12a5e48d7dfeee6409 450 SUPERFAMILY SSF51905 1 315 1.81E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS12575 0c2fa89602445f12a5e48d7dfeee6409 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 3.4E-22 T 28-03-2018 CDW54_RS12575 0c2fa89602445f12a5e48d7dfeee6409 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 3.4E-22 T 28-03-2018 CDW54_RS12575 0c2fa89602445f12a5e48d7dfeee6409 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 3.4E-22 T 28-03-2018 CDW54_RS12575 0c2fa89602445f12a5e48d7dfeee6409 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 235 251 3.4E-22 T 28-03-2018 CDW54_RS12575 0c2fa89602445f12a5e48d7dfeee6409 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 283 3.4E-22 T 28-03-2018 CDW54_RS12575 0c2fa89602445f12a5e48d7dfeee6409 450 Gene3D G3DSA:3.50.50.60 115 192 2.1E-14 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS02055 93be258379e292bb626f8aaffd9d5f23 406 Gene3D G3DSA:2.130.10.10 2 405 0.0041 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CDW54_RS02055 93be258379e292bb626f8aaffd9d5f23 406 Pfam PF03799 Cell division protein FtsQ 210 323 1.5E-12 T 28-03-2018 IPR005548 Cell division protein FtsQ/DivIB CDW54_RS02055 93be258379e292bb626f8aaffd9d5f23 406 Hamap MF_00912 Cell division protein DivIB [divIB]. 54 337 29.638 T 28-03-2018 IPR026580 Cell division protein DivIB CDW54_RS02055 93be258379e292bb626f8aaffd9d5f23 406 Pfam PF08478 POTRA domain, FtsQ-type 135 206 5.2E-12 T 28-03-2018 IPR013685 POTRA domain, FtsQ-type CDW54_RS08955 d227d3a522772b4d460165a0fb4e4afe 474 Pfam PF13520 Amino acid permease 10 439 1.5E-57 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CDW54_RS08955 d227d3a522772b4d460165a0fb4e4afe 474 TIGRFAM TIGR00905 2A0302: transporter, basic amino acid/polyamine antiporter (APA) family 4 473 4.0E-133 T 28-03-2018 IPR004754 Amino acid antiporter GO:0006865|GO:0016021 CDW54_RS08955 d227d3a522772b4d460165a0fb4e4afe 474 PIRSF PIRSF006060 1 472 2.5E-54 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CDW54_RS03625 ecac070b6ccfab6d9cd0212bc56264f2 307 SMART SM00354 1 71 1.4E-26 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS03625 ecac070b6ccfab6d9cd0212bc56264f2 307 Gene3D G3DSA:3.40.50.2300 180 301 1.4E-5 T 28-03-2018 CDW54_RS03625 ecac070b6ccfab6d9cd0212bc56264f2 307 Gene3D G3DSA:1.10.260.40 3 54 1.5E-18 T 28-03-2018 CDW54_RS03625 ecac070b6ccfab6d9cd0212bc56264f2 307 SUPERFAMILY SSF47413 2 59 2.03E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDW54_RS03625 ecac070b6ccfab6d9cd0212bc56264f2 307 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 59 176 2.2E-22 T 28-03-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain CDW54_RS03625 ecac070b6ccfab6d9cd0212bc56264f2 307 Gene3D G3DSA:3.40.50.2300 55 179 6.4E-23 T 28-03-2018 CDW54_RS03625 ecac070b6ccfab6d9cd0212bc56264f2 307 SUPERFAMILY SSF53822 58 297 2.1E-32 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CDW54_RS03625 ecac070b6ccfab6d9cd0212bc56264f2 307 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 48 9.2E-16 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS06515 7e7ce089bc1966e74618c22cdaa57403 202 Gene3D G3DSA:2.170.120.20 98 186 4.6E-24 T 28-03-2018 IPR020057 Ribosomal protein L25, beta domain CDW54_RS06515 7e7ce089bc1966e74618c22cdaa57403 202 Pfam PF01386 Ribosomal L25p family 5 91 5.5E-18 T 28-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 CDW54_RS06515 7e7ce089bc1966e74618c22cdaa57403 202 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 21 94 9.0E-38 T 28-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 CDW54_RS06515 7e7ce089bc1966e74618c22cdaa57403 202 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 101 181 1.3E-22 T 28-03-2018 IPR020057 Ribosomal protein L25, beta domain CDW54_RS06515 7e7ce089bc1966e74618c22cdaa57403 202 Gene3D G3DSA:2.40.240.10 2 93 2.8E-22 T 28-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CDW54_RS06515 7e7ce089bc1966e74618c22cdaa57403 202 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 3 182 23.874 T 28-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 CDW54_RS06515 7e7ce089bc1966e74618c22cdaa57403 202 SUPERFAMILY SSF50715 1 187 1.36E-51 T 28-03-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CDW54_RS06515 7e7ce089bc1966e74618c22cdaa57403 202 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 5 179 2.8E-45 T 28-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 CDW54_RS12690 79e21807be4ced4986e513597b1507d9 306 SUPERFAMILY SSF82689 206 298 2.75E-5 T 28-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 CDW54_RS12690 79e21807be4ced4986e513597b1507d9 306 Gene3D G3DSA:2.30.30.60 155 205 1.2E-10 T 28-03-2018 CDW54_RS12690 79e21807be4ced4986e513597b1507d9 306 SUPERFAMILY SSF82861 52 138 7.85E-15 T 28-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 CDW54_RS12690 79e21807be4ced4986e513597b1507d9 306 SUPERFAMILY SSF50182 140 203 6.21E-11 T 28-03-2018 IPR010920 LSM domain CDW54_RS12690 79e21807be4ced4986e513597b1507d9 306 Gene3D G3DSA:3.30.70.100 206 300 8.9E-6 T 28-03-2018 CDW54_RS12690 79e21807be4ced4986e513597b1507d9 306 Pfam PF00924 Mechanosensitive ion channel 96 292 8.6E-37 T 28-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CDW54_RS01595 dd617404cba9c1fbb534e770f34e8e13 407 SUPERFAMILY SSF53756 1 378 1.81E-77 T 28-03-2018 CDW54_RS01595 dd617404cba9c1fbb534e770f34e8e13 407 Gene3D G3DSA:3.40.50.2000 191 368 2.1E-38 T 28-03-2018 CDW54_RS01595 dd617404cba9c1fbb534e770f34e8e13 407 Gene3D G3DSA:3.40.50.2000 1 190 6.9E-24 T 28-03-2018 CDW54_RS01595 dd617404cba9c1fbb534e770f34e8e13 407 Pfam PF00534 Glycosyl transferases group 1 192 321 3.1E-28 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CDW54_RS01595 dd617404cba9c1fbb534e770f34e8e13 407 Pfam PF13439 Glycosyltransferase Family 4 15 181 2.6E-35 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CDW54_RS04205 fdddb0508cfc66e16fa8a972846a16ba 245 SMART SM00382 27 223 7.3E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS04205 fdddb0508cfc66e16fa8a972846a16ba 245 Gene3D G3DSA:3.40.50.300 2 243 7.0E-61 T 28-03-2018 CDW54_RS04205 fdddb0508cfc66e16fa8a972846a16ba 245 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS04205 fdddb0508cfc66e16fa8a972846a16ba 245 SUPERFAMILY SSF52540 3 226 6.46E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS04205 fdddb0508cfc66e16fa8a972846a16ba 245 Pfam PF00005 ABC transporter 18 161 2.3E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS09770 b52da4dbbc8201b5dd33d96097c86616 482 Hamap MF_01916 Cardiolipin synthase. 10 482 42.489 T 28-03-2018 IPR030874 Cardiolipin synthase, Firmicutes-type GO:0008808|GO:0032049 CDW54_RS09770 b52da4dbbc8201b5dd33d96097c86616 482 Pfam PF13091 PLD-like domain 135 278 2.5E-18 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CDW54_RS09770 b52da4dbbc8201b5dd33d96097c86616 482 Pfam PF13091 PLD-like domain 324 447 3.2E-21 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CDW54_RS09770 b52da4dbbc8201b5dd33d96097c86616 482 PIRSF PIRSF000850 382 478 0.019 T 28-03-2018 CDW54_RS09770 b52da4dbbc8201b5dd33d96097c86616 482 PIRSF PIRSF000850 284 373 0.036 T 28-03-2018 CDW54_RS09770 b52da4dbbc8201b5dd33d96097c86616 482 PIRSF PIRSF000850 112 291 0.016 T 28-03-2018 CDW54_RS09770 b52da4dbbc8201b5dd33d96097c86616 482 SUPERFAMILY SSF56024 110 312 2.01E-60 T 28-03-2018 CDW54_RS09770 b52da4dbbc8201b5dd33d96097c86616 482 SMART SM00155 218 245 1.3E-5 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CDW54_RS09770 b52da4dbbc8201b5dd33d96097c86616 482 SMART SM00155 395 422 1.5E-6 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CDW54_RS09770 b52da4dbbc8201b5dd33d96097c86616 482 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 4 482 5.7E-166 T 28-03-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 CDW54_RS09770 b52da4dbbc8201b5dd33d96097c86616 482 Pfam PF13396 Phospholipase_D-nuclease N-terminal 15 57 1.3E-11 T 28-03-2018 IPR027379 Cardiolipin synthase N-terminal CDW54_RS09770 b52da4dbbc8201b5dd33d96097c86616 482 Gene3D G3DSA:3.30.870.10 301 470 9.6E-27 T 28-03-2018 CDW54_RS09770 b52da4dbbc8201b5dd33d96097c86616 482 SUPERFAMILY SSF56024 270 467 5.61E-47 T 28-03-2018 CDW54_RS09770 b52da4dbbc8201b5dd33d96097c86616 482 Gene3D G3DSA:3.30.870.10 98 288 2.5E-38 T 28-03-2018 CDW54_RS05885 d36bd7fe8e61dc21ad84bbb675f01bb0 193 Gene3D G3DSA:1.10.10.60 134 183 1.3E-7 T 28-03-2018 CDW54_RS05885 d36bd7fe8e61dc21ad84bbb675f01bb0 193 Pfam PF00239 Resolvase, N terminal domain 3 137 8.1E-24 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CDW54_RS05885 d36bd7fe8e61dc21ad84bbb675f01bb0 193 Gene3D G3DSA:3.40.50.1390 1 106 2.7E-16 T 28-03-2018 CDW54_RS05885 d36bd7fe8e61dc21ad84bbb675f01bb0 193 SUPERFAMILY SSF53041 1 138 1.7E-24 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CDW54_RS05885 d36bd7fe8e61dc21ad84bbb675f01bb0 193 SMART SM00857 3 138 5.9E-20 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CDW54_RS05885 d36bd7fe8e61dc21ad84bbb675f01bb0 193 Gene3D G3DSA:1.20.5.40 107 133 2.2E-8 T 28-03-2018 CDW54_RS01615 9c8b71fa619c2b97f2b95a170e082455 744 SUPERFAMILY SSF46600 350 394 2.22E-7 T 28-03-2018 IPR001943 UVR domain GO:0005515 CDW54_RS01615 9c8b71fa619c2b97f2b95a170e082455 744 SUPERFAMILY SSF52540 418 721 3.34E-76 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS01615 9c8b71fa619c2b97f2b95a170e082455 744 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 639 710 2.9E-21 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CDW54_RS01615 9c8b71fa619c2b97f2b95a170e082455 744 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 547 565 1.0E-37 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CDW54_RS01615 9c8b71fa619c2b97f2b95a170e082455 744 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 473 491 1.0E-37 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CDW54_RS01615 9c8b71fa619c2b97f2b95a170e082455 744 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 580 594 1.0E-37 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CDW54_RS01615 9c8b71fa619c2b97f2b95a170e082455 744 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 518 536 1.0E-37 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CDW54_RS01615 9c8b71fa619c2b97f2b95a170e082455 744 Pfam PF07724 AAA domain (Cdc48 subfamily) 468 631 4.8E-51 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CDW54_RS01615 9c8b71fa619c2b97f2b95a170e082455 744 Gene3D G3DSA:3.40.50.300 102 283 3.2E-26 T 28-03-2018 CDW54_RS01615 9c8b71fa619c2b97f2b95a170e082455 744 Gene3D G3DSA:1.10.8.60 284 419 2.8E-36 T 28-03-2018 CDW54_RS01615 9c8b71fa619c2b97f2b95a170e082455 744 SMART SM01086 639 727 1.5E-25 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CDW54_RS01615 9c8b71fa619c2b97f2b95a170e082455 744 Gene3D G3DSA:3.40.50.300 424 638 2.8E-49 T 28-03-2018 CDW54_RS01615 9c8b71fa619c2b97f2b95a170e082455 744 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 503 521 - T 28-03-2018 IPR028299 ClpA/B, conserved site 2 CDW54_RS01615 9c8b71fa619c2b97f2b95a170e082455 744 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 145 264 3.9E-13 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CDW54_RS01615 9c8b71fa619c2b97f2b95a170e082455 744 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 236 248 - T 28-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 CDW54_RS01615 9c8b71fa619c2b97f2b95a170e082455 744 Gene3D G3DSA:1.10.8.60 639 741 1.6E-19 T 28-03-2018 CDW54_RS01615 9c8b71fa619c2b97f2b95a170e082455 744 SUPERFAMILY SSF52540 102 354 2.09E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS01615 9c8b71fa619c2b97f2b95a170e082455 744 SMART SM00382 469 640 1.4E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS01615 9c8b71fa619c2b97f2b95a170e082455 744 SMART SM00382 140 280 1.1E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS01615 9c8b71fa619c2b97f2b95a170e082455 744 Pfam PF02151 UvrB/uvrC motif 355 389 4.5E-8 T 28-03-2018 IPR001943 UVR domain GO:0005515 CDW54_RS04375 16b392a10133196a16aa08c83d912436 584 SUPERFAMILY SSF90123 20 314 1.83E-48 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CDW54_RS04375 16b392a10133196a16aa08c83d912436 584 Gene3D G3DSA:1.20.1560.10 1 330 2.9E-42 T 28-03-2018 CDW54_RS04375 16b392a10133196a16aa08c83d912436 584 Pfam PF00664 ABC transporter transmembrane region 33 304 2.2E-29 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CDW54_RS04375 16b392a10133196a16aa08c83d912436 584 SUPERFAMILY SSF52540 340 582 2.89E-86 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS04375 16b392a10133196a16aa08c83d912436 584 Gene3D G3DSA:3.40.50.300 332 584 1.3E-76 T 28-03-2018 CDW54_RS04375 16b392a10133196a16aa08c83d912436 584 SMART SM00382 375 569 2.0E-19 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS04375 16b392a10133196a16aa08c83d912436 584 ProSitePatterns PS00211 ABC transporters family signature. 487 501 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS04375 16b392a10133196a16aa08c83d912436 584 Pfam PF00005 ABC transporter 367 515 6.0E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS06840 06eb9123e20f24274f4ed648e7510da1 428 SUPERFAMILY SSF50156 315 413 1.97E-18 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CDW54_RS06840 06eb9123e20f24274f4ed648e7510da1 428 PRINTS PR00834 HtrA/DegQ protease family signature 138 150 5.0E-36 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CDW54_RS06840 06eb9123e20f24274f4ed648e7510da1 428 PRINTS PR00834 HtrA/DegQ protease family signature 362 374 5.0E-36 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CDW54_RS06840 06eb9123e20f24274f4ed648e7510da1 428 PRINTS PR00834 HtrA/DegQ protease family signature 264 281 5.0E-36 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CDW54_RS06840 06eb9123e20f24274f4ed648e7510da1 428 PRINTS PR00834 HtrA/DegQ protease family signature 159 179 5.0E-36 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CDW54_RS06840 06eb9123e20f24274f4ed648e7510da1 428 PRINTS PR00834 HtrA/DegQ protease family signature 200 224 5.0E-36 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CDW54_RS06840 06eb9123e20f24274f4ed648e7510da1 428 PRINTS PR00834 HtrA/DegQ protease family signature 242 259 5.0E-36 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CDW54_RS06840 06eb9123e20f24274f4ed648e7510da1 428 SUPERFAMILY SSF50494 75 313 2.94E-57 T 28-03-2018 IPR009003 Peptidase S1, PA clan CDW54_RS06840 06eb9123e20f24274f4ed648e7510da1 428 Pfam PF13180 PDZ domain 316 413 3.3E-23 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CDW54_RS06840 06eb9123e20f24274f4ed648e7510da1 428 Gene3D G3DSA:2.30.42.10 316 423 2.6E-24 T 28-03-2018 CDW54_RS06840 06eb9123e20f24274f4ed648e7510da1 428 Gene3D G3DSA:2.40.10.10 201 315 6.6E-35 T 28-03-2018 CDW54_RS06840 06eb9123e20f24274f4ed648e7510da1 428 Gene3D G3DSA:2.40.10.10 71 200 1.6E-29 T 28-03-2018 CDW54_RS06840 06eb9123e20f24274f4ed648e7510da1 428 SMART SM00228 316 404 4.1E-9 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CDW54_RS06840 06eb9123e20f24274f4ed648e7510da1 428 Pfam PF13365 Trypsin-like peptidase domain 126 271 3.5E-33 T 28-03-2018 CDW54_RS02005 23d28cd99d2a58a572244edc4873fafd 215 SMART SM00899 142 214 4.9E-4 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CDW54_RS02005 23d28cd99d2a58a572244edc4873fafd 215 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 62 130 2.4E-28 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CDW54_RS02005 23d28cd99d2a58a572244edc4873fafd 215 SUPERFAMILY SSF46785 1 61 3.24E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS02005 23d28cd99d2a58a572244edc4873fafd 215 SUPERFAMILY SSF47979 62 139 1.96E-26 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CDW54_RS02005 23d28cd99d2a58a572244edc4873fafd 215 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 2 59 8.3E-16 T 28-03-2018 IPR022687 DTXR-type HTH domain GO:0003677 CDW54_RS02005 23d28cd99d2a58a572244edc4873fafd 215 SUPERFAMILY SSF50037 146 214 3.2E-5 T 28-03-2018 IPR008988 Transcriptional repressor, C-terminal CDW54_RS02005 23d28cd99d2a58a572244edc4873fafd 215 Gene3D G3DSA:1.10.10.10 1 71 7.7E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS02005 23d28cd99d2a58a572244edc4873fafd 215 Pfam PF04023 FeoA domain 143 213 2.5E-8 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CDW54_RS02005 23d28cd99d2a58a572244edc4873fafd 215 Gene3D G3DSA:1.10.60.10 72 126 1.5E-22 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CDW54_RS02005 23d28cd99d2a58a572244edc4873fafd 215 Gene3D G3DSA:2.30.30.90 140 215 1.6E-10 T 28-03-2018 CDW54_RS02005 23d28cd99d2a58a572244edc4873fafd 215 SMART SM00529 23 122 5.8E-38 T 28-03-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 CDW54_RS04560 65493ef787538df5bf0520cd4a246133 804 SUPERFAMILY SSF52374 411 624 8.45E-144 T 28-03-2018 CDW54_RS04560 65493ef787538df5bf0520cd4a246133 804 SUPERFAMILY SSF52374 1 224 8.45E-144 T 28-03-2018 CDW54_RS04560 65493ef787538df5bf0520cd4a246133 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 184 197 1.8E-56 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CDW54_RS04560 65493ef787538df5bf0520cd4a246133 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 213 232 1.8E-56 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CDW54_RS04560 65493ef787538df5bf0520cd4a246133 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 557 567 1.8E-56 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CDW54_RS04560 65493ef787538df5bf0520cd4a246133 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 524 546 1.8E-56 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CDW54_RS04560 65493ef787538df5bf0520cd4a246133 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 126 143 1.8E-56 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CDW54_RS04560 65493ef787538df5bf0520cd4a246133 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 152 168 1.8E-56 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CDW54_RS04560 65493ef787538df5bf0520cd4a246133 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 485 503 1.8E-56 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CDW54_RS04560 65493ef787538df5bf0520cd4a246133 804 Gene3D G3DSA:3.40.50.620 358 604 5.8E-77 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDW54_RS04560 65493ef787538df5bf0520cd4a246133 804 Pfam PF08264 Anticodon-binding domain of tRNA 656 764 9.0E-20 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CDW54_RS04560 65493ef787538df5bf0520cd4a246133 804 Gene3D G3DSA:1.10.730.10 605 740 1.2E-31 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDW54_RS04560 65493ef787538df5bf0520cd4a246133 804 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 3 803 0.0 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CDW54_RS04560 65493ef787538df5bf0520cd4a246133 804 Gene3D G3DSA:3.40.50.620 1 310 2.3E-97 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDW54_RS04560 65493ef787538df5bf0520cd4a246133 804 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 413 603 8.8E-20 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDW54_RS04560 65493ef787538df5bf0520cd4a246133 804 SUPERFAMILY SSF50677 224 410 2.3E-56 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CDW54_RS04560 65493ef787538df5bf0520cd4a246133 804 SUPERFAMILY SSF47323 618 803 2.06E-42 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDW54_RS04560 65493ef787538df5bf0520cd4a246133 804 Pfam PF09334 tRNA synthetases class I (M) 39 160 5.6E-16 T 28-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDW54_RS04560 65493ef787538df5bf0520cd4a246133 804 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 2 803 23.103 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CDW54_RS04560 65493ef787538df5bf0520cd4a246133 804 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 219 399 1.6E-67 T 28-03-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 CDW54_RS04560 65493ef787538df5bf0520cd4a246133 804 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 52 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDW54_RS02485 99c3975cacd101cd1b674c232fd5869e 130 SUPERFAMILY SSF46955 13 89 5.95E-19 T 28-03-2018 IPR009061 Putative DNA-binding domain CDW54_RS02485 99c3975cacd101cd1b674c232fd5869e 130 ProSitePatterns PS00552 MerR-type HTH domain signature. 16 38 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CDW54_RS02485 99c3975cacd101cd1b674c232fd5869e 130 Gene3D G3DSA:1.10.1660.10 2 115 3.6E-21 T 28-03-2018 CDW54_RS02485 99c3975cacd101cd1b674c232fd5869e 130 SMART SM00422 13 81 7.9E-20 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CDW54_RS02485 99c3975cacd101cd1b674c232fd5869e 130 Pfam PF13411 MerR HTH family regulatory protein 14 78 7.5E-18 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CDW54_RS00665 278c1b15991dfa4c8607ed1bc4d38b52 315 SUPERFAMILY SSF53822 58 300 4.93E-45 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CDW54_RS00665 278c1b15991dfa4c8607ed1bc4d38b52 315 Gene3D G3DSA:3.40.50.2300 155 315 2.7E-31 T 28-03-2018 CDW54_RS00665 278c1b15991dfa4c8607ed1bc4d38b52 315 SMART SM00354 1 72 1.3E-28 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS00665 278c1b15991dfa4c8607ed1bc4d38b52 315 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 1.5E-19 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS00665 278c1b15991dfa4c8607ed1bc4d38b52 315 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 28-03-2018 CDW54_RS00665 278c1b15991dfa4c8607ed1bc4d38b52 315 SUPERFAMILY SSF47413 1 59 6.28E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDW54_RS00665 278c1b15991dfa4c8607ed1bc4d38b52 315 Pfam PF13377 Periplasmic binding protein-like domain 157 314 1.3E-23 T 28-03-2018 CDW54_RS00665 278c1b15991dfa4c8607ed1bc4d38b52 315 Gene3D G3DSA:1.10.260.40 3 57 1.6E-19 T 28-03-2018 CDW54_RS00665 278c1b15991dfa4c8607ed1bc4d38b52 315 Gene3D G3DSA:3.40.50.2300 58 154 2.5E-8 T 28-03-2018 CDW54_RS00665 278c1b15991dfa4c8607ed1bc4d38b52 315 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 3.2E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS00665 278c1b15991dfa4c8607ed1bc4d38b52 315 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 3.2E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS05075 90297e9179e41af3bd8f2eab74c8b3d6 286 SUPERFAMILY SSF55315 46 118 1.71E-16 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CDW54_RS05075 90297e9179e41af3bd8f2eab74c8b3d6 286 Gene3D G3DSA:3.40.1280.10 122 286 5.8E-46 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CDW54_RS05075 90297e9179e41af3bd8f2eab74c8b3d6 286 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 46 283 2.7E-80 T 28-03-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 CDW54_RS05075 90297e9179e41af3bd8f2eab74c8b3d6 286 Gene3D G3DSA:3.30.1330.30 34 117 2.8E-17 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CDW54_RS05075 90297e9179e41af3bd8f2eab74c8b3d6 286 SMART SM00967 47 121 1.2E-17 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CDW54_RS05075 90297e9179e41af3bd8f2eab74c8b3d6 286 SUPERFAMILY SSF75217 109 284 3.6E-47 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CDW54_RS05075 90297e9179e41af3bd8f2eab74c8b3d6 286 Pfam PF00588 SpoU rRNA Methylase family 138 277 8.6E-40 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CDW54_RS05075 90297e9179e41af3bd8f2eab74c8b3d6 286 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 47 120 3.4E-19 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CDW54_RS06235 b4c7f5400fc0f622379d3578ffa92589 251 SMART SM00382 26 213 1.4E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS06235 b4c7f5400fc0f622379d3578ffa92589 251 Pfam PF00005 ABC transporter 17 164 3.0E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS06235 b4c7f5400fc0f622379d3578ffa92589 251 SUPERFAMILY SSF52540 2 226 1.05E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS06235 b4c7f5400fc0f622379d3578ffa92589 251 Gene3D G3DSA:3.40.50.300 1 235 1.1E-59 T 28-03-2018 CDW54_RS07045 d59384533426b5f871537f6cc2dc4507 246 Gene3D G3DSA:3.30.70.660 107 244 2.1E-40 T 28-03-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDW54_RS07045 d59384533426b5f871537f6cc2dc4507 246 Gene3D G3DSA:3.30.70.580 1 106 2.1E-30 T 28-03-2018 CDW54_RS07045 d59384533426b5f871537f6cc2dc4507 246 PIRSF PIRSF001430 1 246 1.8E-77 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDW54_RS07045 d59384533426b5f871537f6cc2dc4507 246 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 245 34.596 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDW54_RS07045 d59384533426b5f871537f6cc2dc4507 246 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 2 240 7.8E-62 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDW54_RS07045 d59384533426b5f871537f6cc2dc4507 246 SUPERFAMILY SSF55120 1 245 8.2E-80 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDW54_RS07045 d59384533426b5f871537f6cc2dc4507 246 Pfam PF01416 tRNA pseudouridine synthase 144 245 1.7E-27 T 28-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDW54_RS07045 d59384533426b5f871537f6cc2dc4507 246 Pfam PF01416 tRNA pseudouridine synthase 8 105 2.7E-7 T 28-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDW54_RS10365 7697b1a29cc6838fe81199865798a410 167 Pfam PF04463 Protein of unknown function (DUF523) 2 146 7.5E-42 T 28-03-2018 IPR007553 Domain of unknown function DUF523 CDW54_RS05605 29526536a866aff6e9ca4a2a64aacca4 70 Pfam PF01381 Helix-turn-helix 8 61 1.2E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDW54_RS05605 29526536a866aff6e9ca4a2a64aacca4 70 SUPERFAMILY SSF47413 5 65 1.97E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDW54_RS05605 29526536a866aff6e9ca4a2a64aacca4 70 SMART SM00530 6 61 3.4E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDW54_RS05605 29526536a866aff6e9ca4a2a64aacca4 70 Gene3D G3DSA:1.10.260.40 4 66 4.8E-19 T 28-03-2018 CDW54_RS10750 8de0f2c955dc5f912c8e7414ae0e0bf4 326 Gene3D G3DSA:1.10.260.40 17 64 1.2E-16 T 28-03-2018 CDW54_RS10750 8de0f2c955dc5f912c8e7414ae0e0bf4 326 Gene3D G3DSA:3.40.50.2300 70 167 5.8E-6 T 28-03-2018 CDW54_RS10750 8de0f2c955dc5f912c8e7414ae0e0bf4 326 SUPERFAMILY SSF53822 72 326 3.53E-46 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CDW54_RS10750 8de0f2c955dc5f912c8e7414ae0e0bf4 326 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 28-03-2018 CDW54_RS10750 8de0f2c955dc5f912c8e7414ae0e0bf4 326 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 1.1E-6 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS10750 8de0f2c955dc5f912c8e7414ae0e0bf4 326 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 1.1E-6 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS10750 8de0f2c955dc5f912c8e7414ae0e0bf4 326 Gene3D G3DSA:3.40.50.2300 168 326 6.2E-37 T 28-03-2018 CDW54_RS10750 8de0f2c955dc5f912c8e7414ae0e0bf4 326 SUPERFAMILY SSF47413 3 51 7.69E-12 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDW54_RS10750 8de0f2c955dc5f912c8e7414ae0e0bf4 326 Gene3D G3DSA:1.10.10.60 1 16 0.096 T 28-03-2018 CDW54_RS10750 8de0f2c955dc5f912c8e7414ae0e0bf4 326 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 2.5E-15 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS10750 8de0f2c955dc5f912c8e7414ae0e0bf4 326 SMART SM00354 1 70 1.7E-12 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS10750 8de0f2c955dc5f912c8e7414ae0e0bf4 326 Pfam PF13377 Periplasmic binding protein-like domain 160 325 1.6E-34 T 28-03-2018 CDW54_RS12295 2c603c034aaefca24768e359519d7092 284 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 7 279 5.0E-67 T 28-03-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CDW54_RS12295 2c603c034aaefca24768e359519d7092 284 Gene3D G3DSA:3.40.50.10860 1 116 1.3E-42 T 28-03-2018 CDW54_RS12295 2c603c034aaefca24768e359519d7092 284 Gene3D G3DSA:3.40.50.720 117 284 1.2E-28 T 28-03-2018 CDW54_RS12295 2c603c034aaefca24768e359519d7092 284 SUPERFAMILY SSF51735 106 282 2.5E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS12295 2c603c034aaefca24768e359519d7092 284 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 11 93 2.3E-27 T 28-03-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CDW54_RS12295 2c603c034aaefca24768e359519d7092 284 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 6 284 32.006 T 28-03-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CDW54_RS12295 2c603c034aaefca24768e359519d7092 284 SUPERFAMILY SSF53223 1 105 1.09E-33 T 28-03-2018 CDW54_RS06255 bec687370f2cb3daf9228d597937d349 299 Gene3D G3DSA:3.60.21.10 1 244 7.3E-20 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CDW54_RS06255 bec687370f2cb3daf9228d597937d349 299 TIGRFAM TIGR03729 acc_ester: putative phosphoesterase 3 242 5.3E-82 T 28-03-2018 IPR022302 Phosphoesterase, putative CDW54_RS06255 bec687370f2cb3daf9228d597937d349 299 SUPERFAMILY SSF56300 3 117 1.44E-19 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CDW54_RS06255 bec687370f2cb3daf9228d597937d349 299 SUPERFAMILY SSF56300 149 247 1.44E-19 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CDW54_RS06255 bec687370f2cb3daf9228d597937d349 299 Pfam PF00149 Calcineurin-like phosphoesterase 3 223 5.5E-6 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CDW54_RS01550 02857ad05d0a637de633f910e238a347 411 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 252 366 1.8E-40 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CDW54_RS01550 02857ad05d0a637de633f910e238a347 411 SUPERFAMILY SSF53901 1 249 1.82E-72 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDW54_RS01550 02857ad05d0a637de633f910e238a347 411 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 153 169 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CDW54_RS01550 02857ad05d0a637de633f910e238a347 411 Gene3D G3DSA:3.40.47.10 4 257 2.0E-75 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDW54_RS01550 02857ad05d0a637de633f910e238a347 411 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 2 407 2.1E-187 T 28-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 CDW54_RS01550 02857ad05d0a637de633f910e238a347 411 SMART SM00825 Beta-ketoacyl synthase 4 411 2.2E-16 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CDW54_RS01550 02857ad05d0a637de633f910e238a347 411 Gene3D G3DSA:3.40.47.10 260 411 6.8E-54 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDW54_RS01550 02857ad05d0a637de633f910e238a347 411 PIRSF PIRSF000447 1 411 2.5E-178 T 28-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 CDW54_RS01550 02857ad05d0a637de633f910e238a347 411 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1 244 1.6E-56 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CDW54_RS01550 02857ad05d0a637de633f910e238a347 411 SUPERFAMILY SSF53901 212 409 1.21E-73 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDW54_RS05730 549dbbb1bf6327d0d1cc6ccaba9cbbd9 430 SUPERFAMILY SSF52540 1 427 2.23E-176 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS05730 549dbbb1bf6327d0d1cc6ccaba9cbbd9 430 Gene3D G3DSA:3.40.440.10 1 149 6.9E-53 T 28-03-2018 CDW54_RS05730 549dbbb1bf6327d0d1cc6ccaba9cbbd9 430 Gene3D G3DSA:3.40.440.10 150 264 1.1E-28 T 28-03-2018 CDW54_RS05730 549dbbb1bf6327d0d1cc6ccaba9cbbd9 430 SMART SM00788 3 422 1.7E-295 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CDW54_RS05730 549dbbb1bf6327d0d1cc6ccaba9cbbd9 430 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 430 213.469 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CDW54_RS05730 549dbbb1bf6327d0d1cc6ccaba9cbbd9 430 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 28-03-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CDW54_RS05730 549dbbb1bf6327d0d1cc6ccaba9cbbd9 430 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 425 1.8E-188 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CDW54_RS05730 549dbbb1bf6327d0d1cc6ccaba9cbbd9 430 Gene3D G3DSA:3.90.170.10 265 429 2.1E-68 T 28-03-2018 CDW54_RS05730 549dbbb1bf6327d0d1cc6ccaba9cbbd9 430 Pfam PF00709 Adenylosuccinate synthetase 4 420 7.5E-184 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CDW54_RS05730 549dbbb1bf6327d0d1cc6ccaba9cbbd9 430 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 131 142 - T 28-03-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CDW54_RS04545 0a4a76dd6c02ddeee6f4d520d5ebe5cc 594 Pfam PF00664 ABC transporter transmembrane region 29 308 5.9E-43 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CDW54_RS04545 0a4a76dd6c02ddeee6f4d520d5ebe5cc 594 SMART SM00382 380 566 1.7E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS04545 0a4a76dd6c02ddeee6f4d520d5ebe5cc 594 Gene3D G3DSA:3.40.50.300 343 593 3.1E-72 T 28-03-2018 CDW54_RS04545 0a4a76dd6c02ddeee6f4d520d5ebe5cc 594 Gene3D G3DSA:1.20.1560.10 1 342 9.8E-68 T 28-03-2018 CDW54_RS04545 0a4a76dd6c02ddeee6f4d520d5ebe5cc 594 Pfam PF00005 ABC transporter 372 520 1.6E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS04545 0a4a76dd6c02ddeee6f4d520d5ebe5cc 594 ProSitePatterns PS00211 ABC transporters family signature. 492 506 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS04545 0a4a76dd6c02ddeee6f4d520d5ebe5cc 594 SUPERFAMILY SSF90123 14 340 2.49E-71 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CDW54_RS04545 0a4a76dd6c02ddeee6f4d520d5ebe5cc 594 SUPERFAMILY SSF52540 346 591 7.1E-88 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS03555 351b078a2678a185da92a3ad50831670 359 SUPERFAMILY SSF53822 79 354 5.15E-58 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CDW54_RS03555 351b078a2678a185da92a3ad50831670 359 Pfam PF13377 Periplasmic binding protein-like domain 194 354 7.6E-28 T 28-03-2018 CDW54_RS03555 351b078a2678a185da92a3ad50831670 359 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 6.6E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDW54_RS03555 351b078a2678a185da92a3ad50831670 359 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 6.6E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDW54_RS03555 351b078a2678a185da92a3ad50831670 359 Gene3D G3DSA:3.40.50.2300 193 357 1.3E-36 T 28-03-2018 CDW54_RS03555 351b078a2678a185da92a3ad50831670 359 SMART SM00345 7 66 1.3E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDW54_RS03555 351b078a2678a185da92a3ad50831670 359 Gene3D G3DSA:1.10.10.10 1 68 1.4E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS03555 351b078a2678a185da92a3ad50831670 359 Gene3D G3DSA:3.40.50.2300 77 192 1.4E-29 T 28-03-2018 CDW54_RS03555 351b078a2678a185da92a3ad50831670 359 Pfam PF00392 Bacterial regulatory proteins, gntR family 3 66 8.4E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDW54_RS03555 351b078a2678a185da92a3ad50831670 359 SUPERFAMILY SSF46785 2 75 1.46E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS01535 924031292b5044d8afd980e9d0859c8a 459 SMART SM00878 336 443 9.3E-54 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CDW54_RS01535 924031292b5044d8afd980e9d0859c8a 459 Gene3D G3DSA:3.30.1490.20 129 201 2.6E-22 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CDW54_RS01535 924031292b5044d8afd980e9d0859c8a 459 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CDW54_RS01535 924031292b5044d8afd980e9d0859c8a 459 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 444 8.8E-208 T 28-03-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 CDW54_RS01535 924031292b5044d8afd980e9d0859c8a 459 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 322 3.0E-77 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CDW54_RS01535 924031292b5044d8afd980e9d0859c8a 459 Gene3D G3DSA:3.40.50.20 1 128 2.3E-54 T 28-03-2018 CDW54_RS01535 924031292b5044d8afd980e9d0859c8a 459 SUPERFAMILY SSF51246 331 445 7.85E-40 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CDW54_RS01535 924031292b5044d8afd980e9d0859c8a 459 Pfam PF02785 Biotin carboxylase C-terminal domain 336 443 3.2E-36 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CDW54_RS01535 924031292b5044d8afd980e9d0859c8a 459 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CDW54_RS01535 924031292b5044d8afd980e9d0859c8a 459 Gene3D G3DSA:3.30.470.20 204 446 1.2E-95 T 28-03-2018 CDW54_RS01535 924031292b5044d8afd980e9d0859c8a 459 SUPERFAMILY SSF56059 83 352 1.77E-73 T 28-03-2018 CDW54_RS01535 924031292b5044d8afd980e9d0859c8a 459 SUPERFAMILY SSF52440 1 113 2.66E-48 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CDW54_RS01535 924031292b5044d8afd980e9d0859c8a 459 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 2.3E-45 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CDW54_RS00900 8515e4da0e1a027049905ed83818ae41 348 SUPERFAMILY SSF56796 7 319 3.92E-7 T 28-03-2018 CDW54_RS00900 8515e4da0e1a027049905ed83818ae41 348 Gene3D G3DSA:3.40.50.1970 1 160 7.3E-5 T 28-03-2018 CDW54_RS09905 0e251117f97ff16a6338a116208d0030 74 Hamap MF_00363 UPF0154 protein . 3 73 22.043 T 28-03-2018 IPR005359 Protein with unknown function UPF0154 CDW54_RS09905 0e251117f97ff16a6338a116208d0030 74 ProDom PD048972 UPF0154 TRANSMEMBRANE MEMBRANE UNCHARACTERIZED FAMILY YNEF SUPERFAMILY MG335.1 EXPORTED MYCGA5700 23 62 3.0E-14 T 28-03-2018 IPR005359 Protein with unknown function UPF0154 CDW54_RS09905 0e251117f97ff16a6338a116208d0030 74 Pfam PF03672 Uncharacterised protein family (UPF0154) 12 70 3.0E-32 T 28-03-2018 IPR005359 Protein with unknown function UPF0154 CDW54_RS09905 0e251117f97ff16a6338a116208d0030 74 Gene3D G3DSA:1.10.238.10 29 74 7.0E-4 T 28-03-2018 CDW54_RS04380 99df8213a45e1d9c3abeff041a989025 113 SUPERFAMILY SSF158622 3 112 1.57E-37 T 28-03-2018 IPR023378 YheA/YmcA-like domain CDW54_RS04380 99df8213a45e1d9c3abeff041a989025 113 Gene3D G3DSA:1.20.1500.10 3 108 1.6E-28 T 28-03-2018 IPR023378 YheA/YmcA-like domain CDW54_RS04380 99df8213a45e1d9c3abeff041a989025 113 Hamap MF_01526 UPF0342 protein . 1 112 20.005 T 28-03-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA CDW54_RS04380 99df8213a45e1d9c3abeff041a989025 113 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 4 107 7.8E-26 T 28-03-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA CDW54_RS11855 1a592d52b3fd4fddb8a1416dfd67dc13 475 PIRSF PIRSF006060 1 475 1.5E-57 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CDW54_RS11855 1a592d52b3fd4fddb8a1416dfd67dc13 475 Pfam PF13520 Amino acid permease 13 451 8.5E-61 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CDW54_RS07505 2fdf20743836db9ccf3de8044978c8b2 293 Pfam PF13732 Domain of unknown function (DUF4162) 212 289 2.8E-8 T 28-03-2018 IPR025302 Domain of unknown function DUF4162 CDW54_RS07505 2fdf20743836db9ccf3de8044978c8b2 293 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS07505 2fdf20743836db9ccf3de8044978c8b2 293 Gene3D G3DSA:3.40.50.300 1 257 8.2E-60 T 28-03-2018 CDW54_RS07505 2fdf20743836db9ccf3de8044978c8b2 293 Pfam PF00005 ABC transporter 20 159 1.6E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS07505 2fdf20743836db9ccf3de8044978c8b2 293 SUPERFAMILY SSF52540 4 226 2.71E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS07505 2fdf20743836db9ccf3de8044978c8b2 293 SMART SM00382 29 207 1.4E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS05980 ecb2caefc6dfad4f4d9d4ba1fac4aa4f 179 ProSitePatterns PS00358 Ribosomal protein L5 signature. 57 73 - T 28-03-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS05980 ecb2caefc6dfad4f4d9d4ba1fac4aa4f 179 Pfam PF00281 Ribosomal protein L5 24 80 1.3E-27 T 28-03-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS05980 ecb2caefc6dfad4f4d9d4ba1fac4aa4f 179 Gene3D G3DSA:3.30.1440.10 1 179 5.0E-81 T 28-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS05980 ecb2caefc6dfad4f4d9d4ba1fac4aa4f 179 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 1 179 44.904 T 28-03-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS05980 ecb2caefc6dfad4f4d9d4ba1fac4aa4f 179 PIRSF PIRSF002161 1 179 3.2E-69 T 28-03-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS05980 ecb2caefc6dfad4f4d9d4ba1fac4aa4f 179 Pfam PF00673 ribosomal L5P family C-terminus 84 177 9.8E-41 T 28-03-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS05980 ecb2caefc6dfad4f4d9d4ba1fac4aa4f 179 SUPERFAMILY SSF55282 3 178 5.89E-78 T 28-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS12595 e0906f90a9c194edc2ce3112f9f01c76 665 SUPERFAMILY SSF52518 341 527 5.52E-64 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CDW54_RS12595 e0906f90a9c194edc2ce3112f9f01c76 665 SUPERFAMILY SSF52922 535 663 1.7E-40 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CDW54_RS12595 e0906f90a9c194edc2ce3112f9f01c76 665 ProSitePatterns PS00801 Transketolase signature 1. 14 34 - T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CDW54_RS12595 e0906f90a9c194edc2ce3112f9f01c76 665 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 6 338 3.3E-152 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CDW54_RS12595 e0906f90a9c194edc2ce3112f9f01c76 665 SMART SM00861 354 525 1.4E-60 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CDW54_RS12595 e0906f90a9c194edc2ce3112f9f01c76 665 Pfam PF02779 Transketolase, pyrimidine binding domain 357 524 7.4E-41 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CDW54_RS12595 e0906f90a9c194edc2ce3112f9f01c76 665 Pfam PF02780 Transketolase, C-terminal domain 553 657 5.0E-11 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CDW54_RS12595 e0906f90a9c194edc2ce3112f9f01c76 665 Gene3D G3DSA:3.40.50.970 359 534 1.3E-43 T 28-03-2018 CDW54_RS12595 e0906f90a9c194edc2ce3112f9f01c76 665 SUPERFAMILY SSF52518 6 325 3.3E-118 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CDW54_RS12595 e0906f90a9c194edc2ce3112f9f01c76 665 TIGRFAM TIGR00232 tktlase_bact: transketolase 10 664 1.9E-289 T 28-03-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 CDW54_RS12595 e0906f90a9c194edc2ce3112f9f01c76 665 Gene3D G3DSA:3.40.50.970 4 358 1.4E-112 T 28-03-2018 CDW54_RS12595 e0906f90a9c194edc2ce3112f9f01c76 665 ProSitePatterns PS00802 Transketolase signature 2. 467 483 - T 28-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CDW54_RS12595 e0906f90a9c194edc2ce3112f9f01c76 665 Gene3D G3DSA:3.40.50.920 539 664 1.1E-31 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CDW54_RS09605 d99ca654e9875d2a01d8629c042e7e7a 92 Pfam PF14542 GCN5-related N-acetyl-transferase 14 88 5.3E-24 T 28-03-2018 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase CDW54_RS09605 d99ca654e9875d2a01d8629c042e7e7a 92 Gene3D G3DSA:3.40.630.30 1 92 2.3E-21 T 28-03-2018 CDW54_RS09605 d99ca654e9875d2a01d8629c042e7e7a 92 SUPERFAMILY SSF55729 4 89 2.84E-24 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDW54_RS09925 1229a1b867a5bf7138ae776ee5859da3 626 Gene3D G3DSA:2.70.70.10 467 625 9.2E-53 T 28-03-2018 CDW54_RS09925 1229a1b867a5bf7138ae776ee5859da3 626 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 480 603 6.3E-47 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CDW54_RS09925 1229a1b867a5bf7138ae776ee5859da3 626 SUPERFAMILY SSF51261 472 622 3.31E-51 T 28-03-2018 IPR011055 Duplicated hybrid motif CDW54_RS09925 1229a1b867a5bf7138ae776ee5859da3 626 Gene3D G3DSA:3.30.1360.60 3 77 1.6E-28 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CDW54_RS09925 1229a1b867a5bf7138ae776ee5859da3 626 SUPERFAMILY SSF55604 6 81 4.05E-22 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CDW54_RS09925 1229a1b867a5bf7138ae776ee5859da3 626 Pfam PF02378 Phosphotransferase system, EIIC 108 402 1.1E-26 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CDW54_RS09925 1229a1b867a5bf7138ae776ee5859da3 626 TIGRFAM TIGR01995 PTS-II-ABC-beta: PTS system, beta-glucoside-specific IIABC component 4 624 2.4E-207 T 28-03-2018 IPR011297 Phosphotransferase system, beta-glucoside-specific IIABC component GO:0005886|GO:0008982|GO:0009401 CDW54_RS09925 1229a1b867a5bf7138ae776ee5859da3 626 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 542 554 - T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CDW54_RS09925 1229a1b867a5bf7138ae776ee5859da3 626 Pfam PF00367 phosphotransferase system, EIIB 10 40 1.4E-13 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CDW54_RS09925 1229a1b867a5bf7138ae776ee5859da3 626 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 20 37 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CDW54_RS09925 1229a1b867a5bf7138ae776ee5859da3 626 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 482 600 4.2E-42 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CDW54_RS12510 2ccecc21e71a8a51c0137d9a738df5db 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 399 420 2.2E-64 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CDW54_RS12510 2ccecc21e71a8a51c0137d9a738df5db 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 289 305 2.2E-64 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CDW54_RS12510 2ccecc21e71a8a51c0137d9a738df5db 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 443 461 2.2E-64 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CDW54_RS12510 2ccecc21e71a8a51c0137d9a738df5db 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 330 349 2.2E-64 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CDW54_RS12510 2ccecc21e71a8a51c0137d9a738df5db 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 376 393 2.2E-64 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CDW54_RS12510 2ccecc21e71a8a51c0137d9a738df5db 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 242 261 2.2E-64 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CDW54_RS12510 2ccecc21e71a8a51c0137d9a738df5db 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 145 165 2.2E-64 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CDW54_RS12510 2ccecc21e71a8a51c0137d9a738df5db 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 262 281 2.2E-64 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CDW54_RS12510 2ccecc21e71a8a51c0137d9a738df5db 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 225 241 2.2E-64 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CDW54_RS12510 2ccecc21e71a8a51c0137d9a738df5db 498 PIRSF PIRSF006615 1 497 5.8E-185 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CDW54_RS12510 2ccecc21e71a8a51c0137d9a738df5db 498 SUPERFAMILY SSF55486 4 488 5.78E-107 T 28-03-2018 CDW54_RS12510 2ccecc21e71a8a51c0137d9a738df5db 498 Gene3D G3DSA:1.10.1370.10 61 490 7.7E-39 T 28-03-2018 CDW54_RS12510 2ccecc21e71a8a51c0137d9a738df5db 498 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 3 491 3.8E-146 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CDW54_RS11935 1c91da306c82b1d023d78eb79381c595 220 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 67 6.4E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDW54_RS11935 1c91da306c82b1d023d78eb79381c595 220 SMART SM00345 9 67 1.8E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDW54_RS11935 1c91da306c82b1d023d78eb79381c595 220 Pfam PF07729 FCD domain 81 201 7.4E-17 T 28-03-2018 IPR011711 GntR, C-terminal CDW54_RS11935 1c91da306c82b1d023d78eb79381c595 220 SUPERFAMILY SSF46785 4 71 4.94E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS11935 1c91da306c82b1d023d78eb79381c595 220 SMART SM00895 77 202 3.7E-8 T 28-03-2018 IPR011711 GntR, C-terminal CDW54_RS11935 1c91da306c82b1d023d78eb79381c595 220 SUPERFAMILY SSF48008 79 203 1.78E-15 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CDW54_RS11935 1c91da306c82b1d023d78eb79381c595 220 Gene3D G3DSA:1.10.10.10 1 63 4.0E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS11935 1c91da306c82b1d023d78eb79381c595 220 Gene3D G3DSA:1.20.120.530 64 217 1.3E-18 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CDW54_RS05910 c42a1322d66787c9bd2d7d5093f79996 395 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 146 1.6E-15 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CDW54_RS05910 c42a1322d66787c9bd2d7d5093f79996 395 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CDW54_RS05910 c42a1322d66787c9bd2d7d5093f79996 395 PRINTS PR00315 GTP-binding elongation factor signature 94 105 1.6E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDW54_RS05910 c42a1322d66787c9bd2d7d5093f79996 395 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.6E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDW54_RS05910 c42a1322d66787c9bd2d7d5093f79996 395 PRINTS PR00315 GTP-binding elongation factor signature 131 140 1.6E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDW54_RS05910 c42a1322d66787c9bd2d7d5093f79996 395 PRINTS PR00315 GTP-binding elongation factor signature 78 88 1.6E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDW54_RS05910 c42a1322d66787c9bd2d7d5093f79996 395 PRINTS PR00315 GTP-binding elongation factor signature 14 27 1.6E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDW54_RS05910 c42a1322d66787c9bd2d7d5093f79996 395 Gene3D G3DSA:3.40.50.300 1 74 4.7E-11 T 28-03-2018 CDW54_RS05910 c42a1322d66787c9bd2d7d5093f79996 395 SUPERFAMILY SSF50447 203 302 1.08E-31 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CDW54_RS05910 c42a1322d66787c9bd2d7d5093f79996 395 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 393 3.0E-234 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CDW54_RS05910 c42a1322d66787c9bd2d7d5093f79996 395 Pfam PF00009 Elongation factor Tu GTP binding domain 10 201 3.0E-61 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDW54_RS05910 c42a1322d66787c9bd2d7d5093f79996 395 Gene3D G3DSA:3.40.50.300 75 191 1.9E-32 T 28-03-2018 CDW54_RS05910 c42a1322d66787c9bd2d7d5093f79996 395 SUPERFAMILY SSF52540 9 226 7.77E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS05910 c42a1322d66787c9bd2d7d5093f79996 395 Pfam PF03143 Elongation factor Tu C-terminal domain 299 393 4.8E-35 T 28-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal CDW54_RS05910 c42a1322d66787c9bd2d7d5093f79996 395 SUPERFAMILY SSF50465 299 393 2.19E-36 T 28-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CDW54_RS05910 c42a1322d66787c9bd2d7d5093f79996 395 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 395 60.831 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CDW54_RS05910 c42a1322d66787c9bd2d7d5093f79996 395 Gene3D G3DSA:2.40.30.10 301 393 4.8E-33 T 28-03-2018 CDW54_RS05910 c42a1322d66787c9bd2d7d5093f79996 395 Gene3D G3DSA:2.40.30.10 192 299 2.3E-32 T 28-03-2018 CDW54_RS05910 c42a1322d66787c9bd2d7d5093f79996 395 Pfam PF03144 Elongation factor Tu domain 2 225 294 4.1E-18 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CDW54_RS08170 b85d771d615a2564117e776b5d3a8121 187 Gene3D G3DSA:3.90.79.10 2 187 1.9E-42 T 28-03-2018 CDW54_RS08170 b85d771d615a2564117e776b5d3a8121 187 SUPERFAMILY SSF55811 10 183 1.23E-50 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CDW54_RS08170 b85d771d615a2564117e776b5d3a8121 187 Pfam PF00293 NUDIX domain 48 163 1.3E-19 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CDW54_RS03015 28c52cbbf5e4ac493120a45b032ebd4c 159 Pfam PF04073 Aminoacyl-tRNA editing domain 32 148 1.1E-23 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CDW54_RS03015 28c52cbbf5e4ac493120a45b032ebd4c 159 Gene3D G3DSA:3.90.960.10 1 159 5.4E-28 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CDW54_RS03015 28c52cbbf5e4ac493120a45b032ebd4c 159 SUPERFAMILY SSF55826 5 157 1.7E-31 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CDW54_RS03015 28c52cbbf5e4ac493120a45b032ebd4c 159 PIRSF PIRSF006181 1 159 3.0E-35 T 28-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC CDW54_RS05050 a6d73db0e51f2f27ec707b600f325694 153 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 84 92 2.4E-8 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CDW54_RS05050 a6d73db0e51f2f27ec707b600f325694 153 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 93 102 2.4E-8 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CDW54_RS05050 a6d73db0e51f2f27ec707b600f325694 153 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 4 18 2.4E-8 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CDW54_RS05050 a6d73db0e51f2f27ec707b600f325694 153 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 1 134 1.8E-32 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CDW54_RS05050 a6d73db0e51f2f27ec707b600f325694 153 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 1 131 1.7E-37 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CDW54_RS05050 a6d73db0e51f2f27ec707b600f325694 153 SUPERFAMILY SSF81330 10 127 4.45E-26 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CDW54_RS01685 489700163e2829acdca7200a63cc641b 460 SUPERFAMILY SSF53335 70 457 1.42E-81 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDW54_RS01685 489700163e2829acdca7200a63cc641b 460 Gene3D G3DSA:3.40.50.150 78 152 1.2E-10 T 28-03-2018 CDW54_RS01685 489700163e2829acdca7200a63cc641b 460 Gene3D G3DSA:3.40.50.150 209 456 6.8E-42 T 28-03-2018 CDW54_RS01685 489700163e2829acdca7200a63cc641b 460 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 92 456 1.1E-17 T 28-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 CDW54_RS01685 489700163e2829acdca7200a63cc641b 460 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 389 420 - T 28-03-2018 IPR030390 RNA methyltransferase TrmA, active site CDW54_RS01685 489700163e2829acdca7200a63cc641b 460 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 19 450 3.0E-157 T 28-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 CDW54_RS01685 489700163e2829acdca7200a63cc641b 460 SUPERFAMILY SSF50249 2 63 1.48E-14 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDW54_RS01685 489700163e2829acdca7200a63cc641b 460 Pfam PF01938 TRAM domain 7 62 1.9E-11 T 28-03-2018 IPR002792 TRAM domain CDW54_RS01685 489700163e2829acdca7200a63cc641b 460 Gene3D G3DSA:2.40.50.140 1 77 9.6E-22 T 28-03-2018 CDW54_RS06555 3f7ac62f9c06b5a92008269f94e0d961 155 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 1 147 26.679 T 28-03-2018 IPR003791 Protein of unknown function UPF0178 CDW54_RS06555 3f7ac62f9c06b5a92008269f94e0d961 155 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 16 145 1.6E-40 T 28-03-2018 IPR003791 Protein of unknown function UPF0178 CDW54_RS01060 6930652b103270e6de53215a7eb6c598 283 SUPERFAMILY SSF51430 5 268 1.26E-96 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CDW54_RS01060 6930652b103270e6de53215a7eb6c598 283 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 43 60 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CDW54_RS01060 6930652b103270e6de53215a7eb6c598 283 PIRSF PIRSF000097 1 282 1.6E-86 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CDW54_RS01060 6930652b103270e6de53215a7eb6c598 283 Gene3D G3DSA:3.20.20.100 1 282 1.9E-100 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CDW54_RS01060 6930652b103270e6de53215a7eb6c598 283 PRINTS PR00069 Aldo-keto reductase signature 167 196 1.1E-43 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CDW54_RS01060 6930652b103270e6de53215a7eb6c598 283 PRINTS PR00069 Aldo-keto reductase signature 95 113 1.1E-43 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CDW54_RS01060 6930652b103270e6de53215a7eb6c598 283 PRINTS PR00069 Aldo-keto reductase signature 204 228 1.1E-43 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CDW54_RS01060 6930652b103270e6de53215a7eb6c598 283 PRINTS PR00069 Aldo-keto reductase signature 133 150 1.1E-43 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CDW54_RS01060 6930652b103270e6de53215a7eb6c598 283 PRINTS PR00069 Aldo-keto reductase signature 39 63 1.1E-43 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CDW54_RS01060 6930652b103270e6de53215a7eb6c598 283 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 133 150 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CDW54_RS01060 6930652b103270e6de53215a7eb6c598 283 Pfam PF00248 Aldo/keto reductase family 19 268 5.6E-55 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CDW54_RS01060 6930652b103270e6de53215a7eb6c598 283 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 237 252 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CDW54_RS12625 806aa68525579ee22447ad3d92781be6 144 Pfam PF06305 Lipopolysaccharide assembly protein A domain 24 85 2.0E-16 T 28-03-2018 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 CDW54_RS12625 806aa68525579ee22447ad3d92781be6 144 Gene3D G3DSA:1.20.1000.10 21 141 3.2E-6 T 28-03-2018 CDW54_RS09630 87eccabd75628f100ddc3428a254d693 239 Hamap MF_01393 ATP synthase subunit a [atpB]. 6 238 13.36 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS09630 87eccabd75628f100ddc3428a254d693 239 Pfam PF00119 ATP synthase A chain 21 232 4.9E-54 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS09630 87eccabd75628f100ddc3428a254d693 239 PRINTS PR00123 ATP synthase A subunit signature 218 233 8.1E-16 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS09630 87eccabd75628f100ddc3428a254d693 239 PRINTS PR00123 ATP synthase A subunit signature 78 94 8.1E-16 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS09630 87eccabd75628f100ddc3428a254d693 239 PRINTS PR00123 ATP synthase A subunit signature 164 186 8.1E-16 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS09630 87eccabd75628f100ddc3428a254d693 239 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 17 234 6.9E-46 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS09630 87eccabd75628f100ddc3428a254d693 239 ProSitePatterns PS00449 ATP synthase a subunit signature. 167 176 - T 28-03-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS09630 87eccabd75628f100ddc3428a254d693 239 SUPERFAMILY SSF81336 70 232 6.28E-39 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS09630 87eccabd75628f100ddc3428a254d693 239 Gene3D G3DSA:1.20.120.220 69 237 1.3E-37 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS00515 0d3d74014362464543b7e38fd30e8c3c 318 Pfam PF11728 Putative aromatic acid exporter C-terminal domain 146 308 2.0E-47 T 28-03-2018 IPR021062 Putative aromatic acid exporter, C-terminal CDW54_RS00515 0d3d74014362464543b7e38fd30e8c3c 318 Pfam PF06081 Aromatic acid exporter family member 1 1 141 3.8E-39 T 28-03-2018 IPR010343 Aromatic acid exporter family member 1 CDW54_RS00820 5a69b5e3d73dcbd1b747ab5baf947130 172 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 1 160 35.851 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CDW54_RS00820 5a69b5e3d73dcbd1b747ab5baf947130 172 Gene3D G3DSA:3.30.1060.10 1 169 6.1E-64 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CDW54_RS00820 5a69b5e3d73dcbd1b747ab5baf947130 172 Pfam PF01625 Peptide methionine sulfoxide reductase 4 154 6.8E-59 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CDW54_RS00820 5a69b5e3d73dcbd1b747ab5baf947130 172 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 2 152 3.8E-58 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CDW54_RS00820 5a69b5e3d73dcbd1b747ab5baf947130 172 SUPERFAMILY SSF55068 1 157 1.44E-68 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CDW54_RS06395 0edc29f91f21d50b6770bb8e46c165ef 200 Gene3D G3DSA:1.10.340.30 50 80 0.37 T 28-03-2018 CDW54_RS06395 0edc29f91f21d50b6770bb8e46c165ef 200 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 198 1.9E-54 T 28-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 CDW54_RS06395 0edc29f91f21d50b6770bb8e46c165ef 200 Gene3D G3DSA:1.10.150.20 81 138 1.4E-13 T 28-03-2018 CDW54_RS06395 0edc29f91f21d50b6770bb8e46c165ef 200 Pfam PF07499 RuvA, C-terminal domain 153 198 1.5E-13 T 28-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 CDW54_RS06395 0edc29f91f21d50b6770bb8e46c165ef 200 Gene3D G3DSA:1.10.8.10 151 197 1.2E-10 T 28-03-2018 CDW54_RS06395 0edc29f91f21d50b6770bb8e46c165ef 200 SMART SM00278 107 126 2.7 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CDW54_RS06395 0edc29f91f21d50b6770bb8e46c165ef 200 SMART SM00278 72 91 1.1 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CDW54_RS06395 0edc29f91f21d50b6770bb8e46c165ef 200 SUPERFAMILY SSF50249 1 62 1.6E-16 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDW54_RS06395 0edc29f91f21d50b6770bb8e46c165ef 200 Pfam PF14520 Helix-hairpin-helix domain 71 128 2.1E-13 T 28-03-2018 CDW54_RS06395 0edc29f91f21d50b6770bb8e46c165ef 200 SUPERFAMILY SSF47781 65 136 1.49E-21 T 28-03-2018 IPR010994 RuvA domain 2-like CDW54_RS06395 0edc29f91f21d50b6770bb8e46c165ef 200 SUPERFAMILY SSF46929 152 198 2.22E-9 T 28-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 CDW54_RS06395 0edc29f91f21d50b6770bb8e46c165ef 200 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 198 30.931 T 28-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 CDW54_RS06395 0edc29f91f21d50b6770bb8e46c165ef 200 Gene3D G3DSA:2.40.50.140 1 49 5.2E-20 T 28-03-2018 CDW54_RS06395 0edc29f91f21d50b6770bb8e46c165ef 200 Pfam PF01330 RuvA N terminal domain 1 61 4.3E-19 T 28-03-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 CDW54_RS01025 fbaff109933699c44bd3fb7f2147820c 286 Pfam PF04018 Domain of unknown function (DUF368) 29 252 5.7E-32 T 28-03-2018 IPR007163 Protein of unknown function DUF368 CDW54_RS11270 1e142e51f58ede7b6a28d71aee89b48f 340 Gene3D G3DSA:3.30.70.1140 1 70 6.5E-23 T 28-03-2018 CDW54_RS11270 1e142e51f58ede7b6a28d71aee89b48f 340 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 71 328 8.1E-122 T 28-03-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CDW54_RS11270 1e142e51f58ede7b6a28d71aee89b48f 340 Pfam PF00793 DAHP synthetase I family 86 327 1.5E-70 T 28-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 CDW54_RS11270 1e142e51f58ede7b6a28d71aee89b48f 340 SUPERFAMILY SSF51569 1 334 5.86E-114 T 28-03-2018 CDW54_RS11270 1e142e51f58ede7b6a28d71aee89b48f 340 Gene3D G3DSA:3.20.20.70 71 333 8.2E-78 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDW54_RS00395 53776a6cf2364e0c5c248eb5ed8ada61 347 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 3 343 46.934 T 28-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CDW54_RS00395 53776a6cf2364e0c5c248eb5ed8ada61 347 Gene3D G3DSA:3.30.1330.10 29 158 1.8E-52 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CDW54_RS00395 53776a6cf2364e0c5c248eb5ed8ada61 347 SUPERFAMILY SSF55326 3 166 1.79E-47 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CDW54_RS00395 53776a6cf2364e0c5c248eb5ed8ada61 347 Gene3D G3DSA:3.90.650.10 168 343 5.6E-63 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CDW54_RS00395 53776a6cf2364e0c5c248eb5ed8ada61 347 Pfam PF02769 AIR synthase related protein, C-terminal domain 174 341 7.7E-36 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CDW54_RS00395 53776a6cf2364e0c5c248eb5ed8ada61 347 SUPERFAMILY SSF56042 169 341 1.36E-59 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CDW54_RS00395 53776a6cf2364e0c5c248eb5ed8ada61 347 Pfam PF00586 AIR synthase related protein, N-terminal domain 58 160 6.4E-16 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CDW54_RS00395 53776a6cf2364e0c5c248eb5ed8ada61 347 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 4 334 8.4E-140 T 28-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CDW54_RS03415 8ac0cb5326dc446555c16f94d317a4c5 383 PRINTS PR00084 Mannitol dehydrogenase signature 150 163 1.0E-19 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CDW54_RS03415 8ac0cb5326dc446555c16f94d317a4c5 383 PRINTS PR00084 Mannitol dehydrogenase signature 3 13 1.0E-19 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CDW54_RS03415 8ac0cb5326dc446555c16f94d317a4c5 383 PRINTS PR00084 Mannitol dehydrogenase signature 168 183 1.0E-19 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CDW54_RS03415 8ac0cb5326dc446555c16f94d317a4c5 383 PRINTS PR00084 Mannitol dehydrogenase signature 116 129 1.0E-19 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CDW54_RS03415 8ac0cb5326dc446555c16f94d317a4c5 383 Hamap MF_00196 Mannitol-1-phosphate 5-dehydrogenase [mtlD]. 1 376 39.927 T 28-03-2018 IPR023028 Mannitol-1-phosphate 5-dehydrogenase GO:0008926|GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CDW54_RS03415 8ac0cb5326dc446555c16f94d317a4c5 383 SUPERFAMILY SSF51735 1 201 2.14E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS03415 8ac0cb5326dc446555c16f94d317a4c5 383 Gene3D G3DSA:1.10.1040.10 201 383 3.6E-41 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CDW54_RS03415 8ac0cb5326dc446555c16f94d317a4c5 383 Gene3D G3DSA:3.40.50.720 1 76 4.1E-7 T 28-03-2018 CDW54_RS03415 8ac0cb5326dc446555c16f94d317a4c5 383 Gene3D G3DSA:3.40.50.720 77 197 1.6E-24 T 28-03-2018 CDW54_RS03415 8ac0cb5326dc446555c16f94d317a4c5 383 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 149 366 9.7E-66 T 28-03-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 CDW54_RS03415 8ac0cb5326dc446555c16f94d317a4c5 383 SUPERFAMILY SSF48179 202 365 2.58E-41 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CDW54_RS03415 8ac0cb5326dc446555c16f94d317a4c5 383 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 1 125 6.5E-29 T 28-03-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 CDW54_RS03415 8ac0cb5326dc446555c16f94d317a4c5 383 ProSitePatterns PS00974 Mannitol dehydrogenases signature. 150 162 - T 28-03-2018 IPR023027 Mannitol dehydrogenase, conserved site GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CDW54_RS06040 0901c1764537a182338a421953c4ddb1 121 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 7.6E-53 T 28-03-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS06040 0901c1764537a182338a421953c4ddb1 121 Pfam PF00416 Ribosomal protein S13/S18 3 108 4.7E-33 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS06040 0901c1764537a182338a421953c4ddb1 121 SUPERFAMILY SSF46946 2 113 4.58E-45 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CDW54_RS06040 0901c1764537a182338a421953c4ddb1 121 Gene3D G3DSA:4.10.910.10 67 85 1.1E-18 T 28-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS06040 0901c1764537a182338a421953c4ddb1 121 Gene3D G3DSA:1.10.8.50 1 66 4.1E-24 T 28-03-2018 CDW54_RS06040 0901c1764537a182338a421953c4ddb1 121 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 119 27.998 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS06040 0901c1764537a182338a421953c4ddb1 121 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 28-03-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS06040 0901c1764537a182338a421953c4ddb1 121 Gene3D G3DSA:4.10.910.10 86 121 1.0E-26 T 28-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS06040 0901c1764537a182338a421953c4ddb1 121 PIRSF PIRSF002134 1 121 7.8E-44 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS12370 9344e7a8cfaf78b8c81efd68366102b0 1061 SUPERFAMILY SSF56059 128 399 1.77E-106 T 28-03-2018 CDW54_RS12370 9344e7a8cfaf78b8c81efd68366102b0 1061 Gene3D G3DSA:3.40.50.20 4 117 8.9E-38 T 28-03-2018 CDW54_RS12370 9344e7a8cfaf78b8c81efd68366102b0 1061 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CDW54_RS12370 9344e7a8cfaf78b8c81efd68366102b0 1061 Pfam PF02142 MGS-like domain 950 1039 9.1E-18 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CDW54_RS12370 9344e7a8cfaf78b8c81efd68366102b0 1061 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1061 13.453 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDW54_RS12370 9344e7a8cfaf78b8c81efd68366102b0 1061 Gene3D G3DSA:1.10.1030.10 402 531 2.4E-50 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDW54_RS12370 9344e7a8cfaf78b8c81efd68366102b0 1061 SUPERFAMILY SSF52335 930 1050 5.49E-28 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CDW54_RS12370 9344e7a8cfaf78b8c81efd68366102b0 1061 Gene3D G3DSA:3.30.1490.20 648 737 2.9E-21 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CDW54_RS12370 9344e7a8cfaf78b8c81efd68366102b0 1061 SUPERFAMILY SSF52440 550 668 1.87E-46 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CDW54_RS12370 9344e7a8cfaf78b8c81efd68366102b0 1061 Gene3D G3DSA:3.30.470.20 120 401 2.6E-64 T 28-03-2018 CDW54_RS12370 9344e7a8cfaf78b8c81efd68366102b0 1061 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 830 837 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CDW54_RS12370 9344e7a8cfaf78b8c81efd68366102b0 1061 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1050 0.0 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDW54_RS12370 9344e7a8cfaf78b8c81efd68366102b0 1061 SUPERFAMILY SSF48108 395 546 2.88E-51 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDW54_RS12370 9344e7a8cfaf78b8c81efd68366102b0 1061 Gene3D G3DSA:3.40.50.1380 928 1059 3.2E-33 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CDW54_RS12370 9344e7a8cfaf78b8c81efd68366102b0 1061 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1060 13.212 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDW54_RS12370 9344e7a8cfaf78b8c81efd68366102b0 1061 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 296 303 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CDW54_RS12370 9344e7a8cfaf78b8c81efd68366102b0 1061 SMART SM00851 949 1039 9.6E-23 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CDW54_RS12370 9344e7a8cfaf78b8c81efd68366102b0 1061 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 702 716 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CDW54_RS12370 9344e7a8cfaf78b8c81efd68366102b0 1061 SMART SM01096 420 540 4.4E-68 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDW54_RS12370 9344e7a8cfaf78b8c81efd68366102b0 1061 SUPERFAMILY SSF52440 1 127 2.73E-49 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CDW54_RS12370 9344e7a8cfaf78b8c81efd68366102b0 1061 Gene3D G3DSA:3.30.470.20 738 927 9.5E-40 T 28-03-2018 CDW54_RS12370 9344e7a8cfaf78b8c81efd68366102b0 1061 SUPERFAMILY SSF56059 666 927 4.95E-103 T 28-03-2018 CDW54_RS12370 9344e7a8cfaf78b8c81efd68366102b0 1061 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 423 540 4.7E-43 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDW54_RS12370 9344e7a8cfaf78b8c81efd68366102b0 1061 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 333 3.7E-80 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CDW54_RS12370 9344e7a8cfaf78b8c81efd68366102b0 1061 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 667 867 1.2E-36 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CDW54_RS12370 9344e7a8cfaf78b8c81efd68366102b0 1061 SMART SM01209 674 837 0.0078 T 28-03-2018 CDW54_RS12370 9344e7a8cfaf78b8c81efd68366102b0 1061 Gene3D G3DSA:3.40.50.20 532 647 1.3E-58 T 28-03-2018 CDW54_RS12370 9344e7a8cfaf78b8c81efd68366102b0 1061 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 8.7E-63 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDW54_RS12370 9344e7a8cfaf78b8c81efd68366102b0 1061 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 296 325 8.7E-63 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDW54_RS12370 9344e7a8cfaf78b8c81efd68366102b0 1061 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 378 396 8.7E-63 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDW54_RS12370 9344e7a8cfaf78b8c81efd68366102b0 1061 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 8.7E-63 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDW54_RS12370 9344e7a8cfaf78b8c81efd68366102b0 1061 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 8.7E-63 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDW54_RS12370 9344e7a8cfaf78b8c81efd68366102b0 1061 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 8.7E-63 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDW54_RS12370 9344e7a8cfaf78b8c81efd68366102b0 1061 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 8.7E-63 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDW54_RS09730 c7e62b4e8f2206ee590fa539fdec6e28 106 SUPERFAMILY SSF52794 4 105 3.92E-37 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CDW54_RS09730 c7e62b4e8f2206ee590fa539fdec6e28 106 Gene3D G3DSA:3.40.50.2300 5 106 1.3E-38 T 28-03-2018 CDW54_RS09730 c7e62b4e8f2206ee590fa539fdec6e28 106 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 6 99 5.6E-23 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CDW54_RS07310 219fff9ca6c10375e1a6e0c1d1e20b67 122 Gene3D G3DSA:3.10.180.10 5 121 1.5E-5 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDW54_RS07310 219fff9ca6c10375e1a6e0c1d1e20b67 122 SUPERFAMILY SSF54593 6 116 2.23E-10 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDW54_RS08190 68f25ed07f73f7d84cd9f295724b523b 1088 SUPERFAMILY SSF51126 470 775 1.46E-49 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CDW54_RS08190 68f25ed07f73f7d84cd9f295724b523b 1088 Pfam PF07602 Protein of unknown function (DUF1565) 478 612 1.4E-8 T 28-03-2018 IPR011459 Domain of unknown function DUF1565 CDW54_RS08190 68f25ed07f73f7d84cd9f295724b523b 1088 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 1056 1088 2.3E-4 T 28-03-2018 CDW54_RS08190 68f25ed07f73f7d84cd9f295724b523b 1088 Gene3D G3DSA:2.160.20.10 457 890 2.5E-46 T 28-03-2018 IPR012334 Pectin lyase fold CDW54_RS08190 68f25ed07f73f7d84cd9f295724b523b 1088 SMART SM00710 735 757 1700.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CDW54_RS08190 68f25ed07f73f7d84cd9f295724b523b 1088 SMART SM00710 616 644 7500.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CDW54_RS08190 68f25ed07f73f7d84cd9f295724b523b 1088 SMART SM00710 647 669 1100.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CDW54_RS08190 68f25ed07f73f7d84cd9f295724b523b 1088 SMART SM00710 584 606 130.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CDW54_RS08190 68f25ed07f73f7d84cd9f295724b523b 1088 SMART SM00710 676 708 4700.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CDW54_RS11430 51d102453cf3bb344397c162622fe4e4 209 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 15 200 6.3E-58 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CDW54_RS11430 51d102453cf3bb344397c162622fe4e4 209 SUPERFAMILY SSF52540 15 202 6.45E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS11430 51d102453cf3bb344397c162622fe4e4 209 Pfam PF01121 Dephospho-CoA kinase 15 192 2.6E-60 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CDW54_RS11430 51d102453cf3bb344397c162622fe4e4 209 Gene3D G3DSA:3.40.50.300 3 205 1.6E-42 T 28-03-2018 CDW54_RS11430 51d102453cf3bb344397c162622fe4e4 209 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 13 209 27.009 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CDW54_RS02065 e7bd65b61d890713f8ccdc1a93705c37 453 SUPERFAMILY SSF51984 10 100 7.85E-19 T 28-03-2018 CDW54_RS02065 e7bd65b61d890713f8ccdc1a93705c37 453 Pfam PF08245 Mur ligase middle domain 117 293 3.1E-36 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CDW54_RS02065 e7bd65b61d890713f8ccdc1a93705c37 453 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 10 452 36.311 T 28-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDW54_RS02065 e7bd65b61d890713f8ccdc1a93705c37 453 SUPERFAMILY SSF53623 103 310 1.44E-51 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CDW54_RS02065 e7bd65b61d890713f8ccdc1a93705c37 453 Pfam PF02875 Mur ligase family, glutamate ligase domain 313 381 1.3E-9 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CDW54_RS02065 e7bd65b61d890713f8ccdc1a93705c37 453 Gene3D G3DSA:3.40.1190.10 102 310 3.2E-53 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CDW54_RS02065 e7bd65b61d890713f8ccdc1a93705c37 453 SUPERFAMILY SSF53244 312 452 1.88E-40 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CDW54_RS02065 e7bd65b61d890713f8ccdc1a93705c37 453 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 11 450 3.4E-127 T 28-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDW54_RS02065 e7bd65b61d890713f8ccdc1a93705c37 453 Gene3D G3DSA:3.90.190.20 317 451 5.2E-33 T 28-03-2018 CDW54_RS02065 e7bd65b61d890713f8ccdc1a93705c37 453 Gene3D G3DSA:3.40.50.720 1 101 9.7E-18 T 28-03-2018 CDW54_RS12385 79e3e56e38c3b094b827af1835739ef2 308 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 11 304 3.9E-90 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CDW54_RS12385 79e3e56e38c3b094b827af1835739ef2 308 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 53 60 - T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CDW54_RS12385 79e3e56e38c3b094b827af1835739ef2 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 43 65 3.7E-30 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CDW54_RS12385 79e3e56e38c3b094b827af1835739ef2 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 138 155 3.7E-30 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CDW54_RS12385 79e3e56e38c3b094b827af1835739ef2 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 261 266 3.7E-30 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CDW54_RS12385 79e3e56e38c3b094b827af1835739ef2 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 285 299 3.7E-30 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CDW54_RS12385 79e3e56e38c3b094b827af1835739ef2 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 81 90 3.7E-30 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CDW54_RS12385 79e3e56e38c3b094b827af1835739ef2 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 220 229 3.7E-30 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CDW54_RS12385 79e3e56e38c3b094b827af1835739ef2 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 269 292 7.4E-18 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CDW54_RS12385 79e3e56e38c3b094b827af1835739ef2 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 257 266 7.4E-18 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CDW54_RS12385 79e3e56e38c3b094b827af1835739ef2 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 53 72 7.4E-18 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CDW54_RS12385 79e3e56e38c3b094b827af1835739ef2 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 139 150 7.4E-18 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CDW54_RS12385 79e3e56e38c3b094b827af1835739ef2 308 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 10 306 38.806 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CDW54_RS12385 79e3e56e38c3b094b827af1835739ef2 308 Gene3D G3DSA:3.40.50.1370 3 165 3.9E-54 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CDW54_RS12385 79e3e56e38c3b094b827af1835739ef2 308 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 11 152 1.9E-36 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CDW54_RS12385 79e3e56e38c3b094b827af1835739ef2 308 SUPERFAMILY SSF53671 9 306 4.06E-88 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CDW54_RS12385 79e3e56e38c3b094b827af1835739ef2 308 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 158 302 2.1E-20 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CDW54_RS12385 79e3e56e38c3b094b827af1835739ef2 308 Gene3D G3DSA:3.40.50.1370 166 308 1.2E-40 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CDW54_RS01145 d883b31600f5e501e5e9985a30a61d56 423 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 12 417 4.4E-149 T 28-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 CDW54_RS01145 d883b31600f5e501e5e9985a30a61d56 423 PIRSF PIRSF006351 1 420 6.8E-140 T 28-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 CDW54_RS01145 d883b31600f5e501e5e9985a30a61d56 423 Pfam PF02378 Phosphotransferase system, EIIC 29 349 1.4E-72 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CDW54_RS01145 d883b31600f5e501e5e9985a30a61d56 423 TIGRFAM TIGR00359 cello_pts_IIC: PTS system, cellobiose-specific IIC component 12 417 4.4E-149 T 28-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 CDW54_RS00945 681d2debf4142bb1a83dcf74f2838b91 73 Gene3D G3DSA:3.30.70.20 5 72 8.2E-9 T 28-03-2018 CDW54_RS00945 681d2debf4142bb1a83dcf74f2838b91 73 SUPERFAMILY SSF54862 7 71 2.96E-12 T 28-03-2018 CDW54_RS00945 681d2debf4142bb1a83dcf74f2838b91 73 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 10 67 2.6E-14 T 28-03-2018 CDW54_RS00945 681d2debf4142bb1a83dcf74f2838b91 73 PRINTS PR00352 3Fe-4S ferredoxin signature 18 28 5.2E-5 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CDW54_RS00945 681d2debf4142bb1a83dcf74f2838b91 73 PRINTS PR00352 3Fe-4S ferredoxin signature 7 18 5.2E-5 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CDW54_RS00945 681d2debf4142bb1a83dcf74f2838b91 73 PRINTS PR00352 3Fe-4S ferredoxin signature 55 67 5.2E-5 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CDW54_RS02200 686b787897edb4e67c85d515c3efea0d 114 Pfam PF04327 Cysteine protease Prp 1 107 2.7E-26 T 28-03-2018 IPR007422 Cysteine protease Prp CDW54_RS02200 686b787897edb4e67c85d515c3efea0d 114 Gene3D G3DSA:3.30.70.1490 2 112 3.3E-31 T 28-03-2018 IPR007422 Cysteine protease Prp CDW54_RS02200 686b787897edb4e67c85d515c3efea0d 114 SUPERFAMILY SSF118010 1 109 1.31E-32 T 28-03-2018 IPR007422 Cysteine protease Prp CDW54_RS07605 f5702bbd7bdc81605ed31c977151200c 490 PRINTS PR01036 Tetracycline resistance protein TetB signature 113 133 2.5E-5 T 28-03-2018 CDW54_RS07605 f5702bbd7bdc81605ed31c977151200c 490 PRINTS PR01036 Tetracycline resistance protein TetB signature 143 167 2.5E-5 T 28-03-2018 CDW54_RS07605 f5702bbd7bdc81605ed31c977151200c 490 PRINTS PR01036 Tetracycline resistance protein TetB signature 22 46 2.5E-5 T 28-03-2018 CDW54_RS07605 f5702bbd7bdc81605ed31c977151200c 490 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 18 430 3.6E-108 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CDW54_RS07605 f5702bbd7bdc81605ed31c977151200c 490 Pfam PF07690 Major Facilitator Superfamily 23 414 4.2E-54 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDW54_RS07605 f5702bbd7bdc81605ed31c977151200c 490 Gene3D G3DSA:1.20.1250.20 264 490 3.0E-30 T 28-03-2018 CDW54_RS07605 f5702bbd7bdc81605ed31c977151200c 490 Gene3D G3DSA:1.20.1250.20 1 196 5.8E-36 T 28-03-2018 CDW54_RS07605 f5702bbd7bdc81605ed31c977151200c 490 SUPERFAMILY SSF103473 12 200 5.1E-67 T 28-03-2018 IPR020846 Major facilitator superfamily domain CDW54_RS07605 f5702bbd7bdc81605ed31c977151200c 490 SUPERFAMILY SSF103473 253 425 5.1E-67 T 28-03-2018 IPR020846 Major facilitator superfamily domain CDW54_RS07605 f5702bbd7bdc81605ed31c977151200c 490 SUPERFAMILY SSF103473 454 479 5.1E-67 T 28-03-2018 IPR020846 Major facilitator superfamily domain CDW54_RS07905 62e826573a04a7d74515d76ce161983f 266 SUPERFAMILY SSF54506 3 121 1.36E-27 T 28-03-2018 CDW54_RS07905 62e826573a04a7d74515d76ce161983f 266 Pfam PF01678 Diaminopimelate epimerase 5 115 3.4E-23 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CDW54_RS07905 62e826573a04a7d74515d76ce161983f 266 Pfam PF01678 Diaminopimelate epimerase 150 256 5.9E-20 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CDW54_RS07905 62e826573a04a7d74515d76ce161983f 266 Gene3D G3DSA:3.10.310.10 119 252 2.6E-32 T 28-03-2018 CDW54_RS07905 62e826573a04a7d74515d76ce161983f 266 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 2 258 2.9E-66 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CDW54_RS07905 62e826573a04a7d74515d76ce161983f 266 SUPERFAMILY SSF54506 133 262 1.41E-33 T 28-03-2018 CDW54_RS07905 62e826573a04a7d74515d76ce161983f 266 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 56 70 - T 28-03-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CDW54_RS07905 62e826573a04a7d74515d76ce161983f 266 Gene3D G3DSA:3.10.310.10 1 118 1.1E-31 T 28-03-2018 CDW54_RS07905 62e826573a04a7d74515d76ce161983f 266 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 1 266 28.617 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CDW54_RS03255 1e83bc48ee51ee8f26aabb2970e91be9 355 Pfam PF04055 Radical SAM superfamily 106 278 7.8E-20 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CDW54_RS03255 1e83bc48ee51ee8f26aabb2970e91be9 355 PIRSF PIRSF006004 2 355 3.7E-139 T 28-03-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CDW54_RS03255 1e83bc48ee51ee8f26aabb2970e91be9 355 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 2 352 1.2E-135 T 28-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CDW54_RS03255 1e83bc48ee51ee8f26aabb2970e91be9 355 SUPERFAMILY SSF102114 100 307 2.75E-16 T 28-03-2018 CDW54_RS03255 1e83bc48ee51ee8f26aabb2970e91be9 355 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 3 350 71.524 T 28-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CDW54_RS03255 1e83bc48ee51ee8f26aabb2970e91be9 355 Pfam PF13394 4Fe-4S single cluster domain 111 206 5.9E-7 T 28-03-2018 CDW54_RS03255 1e83bc48ee51ee8f26aabb2970e91be9 355 Gene3D G3DSA:3.20.20.70 10 348 1.7E-39 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDW54_RS11135 f7e76d3af78fc4d2a7f192415be3a5a6 429 Pfam PF05697 Bacterial trigger factor protein (TF) 1 144 1.8E-41 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CDW54_RS11135 f7e76d3af78fc4d2a7f192415be3a5a6 429 SUPERFAMILY SSF54534 89 243 7.07E-41 T 28-03-2018 CDW54_RS11135 f7e76d3af78fc4d2a7f192415be3a5a6 429 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 159 239 3.6E-15 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain CDW54_RS11135 f7e76d3af78fc4d2a7f192415be3a5a6 429 PIRSF PIRSF003095 1 429 2.4E-130 T 28-03-2018 IPR005215 Trigger factor GO:0015031 CDW54_RS11135 f7e76d3af78fc4d2a7f192415be3a5a6 429 SUPERFAMILY SSF102735 1 128 2.09E-35 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CDW54_RS11135 f7e76d3af78fc4d2a7f192415be3a5a6 429 SUPERFAMILY SSF109998 250 425 4.45E-37 T 28-03-2018 IPR027304 Trigger factor/SurA domain CDW54_RS11135 f7e76d3af78fc4d2a7f192415be3a5a6 429 Gene3D G3DSA:1.10.3120.10 213 400 1.4E-52 T 28-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 CDW54_RS11135 f7e76d3af78fc4d2a7f192415be3a5a6 429 TIGRFAM TIGR00115 tig: trigger factor 14 420 5.2E-135 T 28-03-2018 IPR005215 Trigger factor GO:0015031 CDW54_RS11135 f7e76d3af78fc4d2a7f192415be3a5a6 429 Hamap MF_00303 Trigger factor [tig]. 1 428 22.783 T 28-03-2018 IPR005215 Trigger factor GO:0015031 CDW54_RS11135 f7e76d3af78fc4d2a7f192415be3a5a6 429 Gene3D G3DSA:3.30.70.1050 1 119 9.4E-35 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CDW54_RS11135 f7e76d3af78fc4d2a7f192415be3a5a6 429 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 264 421 5.4E-42 T 28-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 CDW54_RS12560 859d965aad2eb951263307bf24669d78 394 PRINTS PR01035 Tetracycline resistance protein signature 19 35 7.6E-42 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CDW54_RS12560 859d965aad2eb951263307bf24669d78 394 PRINTS PR01035 Tetracycline resistance protein signature 49 68 7.6E-42 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CDW54_RS12560 859d965aad2eb951263307bf24669d78 394 PRINTS PR01035 Tetracycline resistance protein signature 165 185 7.6E-42 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CDW54_RS12560 859d965aad2eb951263307bf24669d78 394 PRINTS PR01035 Tetracycline resistance protein signature 107 128 7.6E-42 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CDW54_RS12560 859d965aad2eb951263307bf24669d78 394 PRINTS PR01035 Tetracycline resistance protein signature 80 104 7.6E-42 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CDW54_RS12560 859d965aad2eb951263307bf24669d78 394 PRINTS PR01035 Tetracycline resistance protein signature 254 274 7.6E-42 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CDW54_RS12560 859d965aad2eb951263307bf24669d78 394 PRINTS PR01035 Tetracycline resistance protein signature 137 159 7.6E-42 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CDW54_RS12560 859d965aad2eb951263307bf24669d78 394 PRINTS PR01035 Tetracycline resistance protein signature 346 369 7.6E-42 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CDW54_RS12560 859d965aad2eb951263307bf24669d78 394 Gene3D G3DSA:1.20.1250.20 203 392 5.2E-16 T 28-03-2018 CDW54_RS12560 859d965aad2eb951263307bf24669d78 394 Gene3D G3DSA:1.20.1250.20 3 195 1.7E-31 T 28-03-2018 CDW54_RS12560 859d965aad2eb951263307bf24669d78 394 SUPERFAMILY SSF103473 12 385 6.15E-58 T 28-03-2018 IPR020846 Major facilitator superfamily domain CDW54_RS12560 859d965aad2eb951263307bf24669d78 394 Pfam PF07690 Major Facilitator Superfamily 16 362 1.8E-45 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDW54_RS11940 bea60f65e80f8d8637aaa05b331f1aee 548 Gene3D G3DSA:1.10.1040.10 317 542 9.1E-56 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CDW54_RS11940 bea60f65e80f8d8637aaa05b331f1aee 548 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 240 509 1.6E-27 T 28-03-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 CDW54_RS11940 bea60f65e80f8d8637aaa05b331f1aee 548 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 39 201 1.4E-8 T 28-03-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 CDW54_RS11940 bea60f65e80f8d8637aaa05b331f1aee 548 Gene3D G3DSA:3.40.50.720 8 314 4.9E-61 T 28-03-2018 CDW54_RS11940 bea60f65e80f8d8637aaa05b331f1aee 548 SUPERFAMILY SSF48179 321 539 1.5E-38 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CDW54_RS11940 bea60f65e80f8d8637aaa05b331f1aee 548 SUPERFAMILY SSF51735 9 315 6.3E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS02295 17bc3177a959c1903316ac38b5d8881a 680 PIRSF PIRSF018968 1 680 2.9E-77 T 28-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 CDW54_RS02295 17bc3177a959c1903316ac38b5d8881a 680 Pfam PF02687 FtsX-like permease family 84 178 3.5E-12 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CDW54_RS11495 f27e3911f1905925a1b1608648769f5c 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 115 135 1.8E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDW54_RS11495 f27e3911f1905925a1b1608648769f5c 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 66 81 1.8E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDW54_RS11495 f27e3911f1905925a1b1608648769f5c 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 49 65 1.8E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDW54_RS11495 f27e3911f1905925a1b1608648769f5c 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 85 101 1.8E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDW54_RS11495 f27e3911f1905925a1b1608648769f5c 139 SMART SM00347 25 125 1.3E-22 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDW54_RS11495 f27e3911f1905925a1b1608648769f5c 139 SUPERFAMILY SSF46785 11 137 8.19E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS11495 f27e3911f1905925a1b1608648769f5c 139 Gene3D G3DSA:1.10.10.10 1 139 4.3E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS11495 f27e3911f1905925a1b1608648769f5c 139 Pfam PF01047 MarR family 32 89 1.1E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDW54_RS03465 7ffae3b0d922e767be54f7f0fef8b4fb 289 Gene3D G3DSA:3.10.180.10 8 153 1.3E-15 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDW54_RS03465 7ffae3b0d922e767be54f7f0fef8b4fb 289 Pfam PF14507 CppA C-terminal 164 273 9.0E-23 T 28-03-2018 IPR032703 CppA, C-terminal CDW54_RS03465 7ffae3b0d922e767be54f7f0fef8b4fb 289 SUPERFAMILY SSF54593 10 137 1.06E-15 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDW54_RS03465 7ffae3b0d922e767be54f7f0fef8b4fb 289 Gene3D G3DSA:3.10.180.10 166 286 4.1E-7 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDW54_RS03465 7ffae3b0d922e767be54f7f0fef8b4fb 289 SUPERFAMILY SSF54593 167 274 3.24E-8 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDW54_RS03465 7ffae3b0d922e767be54f7f0fef8b4fb 289 Pfam PF14506 CppA N-terminal 16 98 1.4E-11 T 28-03-2018 IPR032702 CppA, N-terminal CDW54_RS03785 b02718081e2a8ba12815f8c8b44d0a39 719 PRINTS PR01183 Ribonucleotide reductase large chain signature 245 264 1.8E-24 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CDW54_RS03785 b02718081e2a8ba12815f8c8b44d0a39 719 PRINTS PR01183 Ribonucleotide reductase large chain signature 459 481 1.8E-24 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CDW54_RS03785 b02718081e2a8ba12815f8c8b44d0a39 719 PRINTS PR01183 Ribonucleotide reductase large chain signature 569 596 1.8E-24 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CDW54_RS03785 b02718081e2a8ba12815f8c8b44d0a39 719 PRINTS PR01183 Ribonucleotide reductase large chain signature 376 387 1.8E-24 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CDW54_RS03785 b02718081e2a8ba12815f8c8b44d0a39 719 PRINTS PR01183 Ribonucleotide reductase large chain signature 420 443 1.8E-24 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CDW54_RS03785 b02718081e2a8ba12815f8c8b44d0a39 719 PRINTS PR01183 Ribonucleotide reductase large chain signature 487 510 1.8E-24 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CDW54_RS03785 b02718081e2a8ba12815f8c8b44d0a39 719 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 558 580 - T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CDW54_RS03785 b02718081e2a8ba12815f8c8b44d0a39 719 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 95 165 3.2E-12 T 28-03-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CDW54_RS03785 b02718081e2a8ba12815f8c8b44d0a39 719 TIGRFAM TIGR04170 RNR_1b_NrdE: ribonucleoside-diphosphate reductase, class 1b, alpha subunit 11 719 0.0 T 28-03-2018 IPR026459 Ribonucleotide reductase, class 1b, subunit NrdE KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CDW54_RS03785 b02718081e2a8ba12815f8c8b44d0a39 719 SUPERFAMILY SSF48168 14 168 2.22E-40 T 28-03-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CDW54_RS03785 b02718081e2a8ba12815f8c8b44d0a39 719 SUPERFAMILY SSF51998 169 701 7.32E-172 T 28-03-2018 CDW54_RS03785 b02718081e2a8ba12815f8c8b44d0a39 719 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 96 701 4.5E-151 T 28-03-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CDW54_RS03785 b02718081e2a8ba12815f8c8b44d0a39 719 Pfam PF08343 Ribonucleotide reductase N-terminal 11 91 1.9E-28 T 28-03-2018 IPR013554 Ribonucleotide reductase N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CDW54_RS03785 b02718081e2a8ba12815f8c8b44d0a39 719 Pfam PF02867 Ribonucleotide reductase, barrel domain 170 698 7.0E-139 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CDW54_RS03785 b02718081e2a8ba12815f8c8b44d0a39 719 Gene3D G3DSA:3.20.70.20 74 706 1.4E-154 T 28-03-2018 CDW54_RS10430 2e48634ca67650ff6bf795d3604f29da 97 Pfam PF09860 Uncharacterized protein conserved in bacteria (DUF2087) 23 91 3.0E-21 T 28-03-2018 IPR018656 Domain of unknown function DUF2087 CDW54_RS12555 3036fd807c1fe313149bddda96b83e36 232 Gene3D G3DSA:1.10.10.10 3 122 8.9E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS12555 3036fd807c1fe313149bddda96b83e36 232 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 127 198 1.6E-23 T 28-03-2018 IPR006343 DnaD domain CDW54_RS12555 3036fd807c1fe313149bddda96b83e36 232 SUPERFAMILY SSF158499 127 192 2.09E-19 T 28-03-2018 IPR006343 DnaD domain CDW54_RS12555 3036fd807c1fe313149bddda96b83e36 232 Gene3D G3DSA:1.10.10.630 123 198 1.2E-24 T 28-03-2018 IPR034829 DnaD-like domain CDW54_RS12555 3036fd807c1fe313149bddda96b83e36 232 Pfam PF07261 Replication initiation and membrane attachment 127 199 2.1E-24 T 28-03-2018 IPR006343 DnaD domain CDW54_RS10535 b1c0129b078796d30b95bda7950846ea 238 SMART SM00862 157 232 6.3E-29 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDW54_RS10535 b1c0129b078796d30b95bda7950846ea 238 Gene3D G3DSA:1.10.10.10 129 238 4.3E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS10535 b1c0129b078796d30b95bda7950846ea 238 Pfam PF00486 Transcriptional regulatory protein, C terminal 163 232 7.2E-27 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDW54_RS10535 b1c0129b078796d30b95bda7950846ea 238 SMART SM00448 1 114 8.9E-35 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDW54_RS10535 b1c0129b078796d30b95bda7950846ea 238 SUPERFAMILY SSF46894 139 233 1.16E-27 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDW54_RS10535 b1c0129b078796d30b95bda7950846ea 238 Pfam PF00072 Response regulator receiver domain 3 114 1.8E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDW54_RS10535 b1c0129b078796d30b95bda7950846ea 238 Gene3D G3DSA:3.40.50.2300 1 128 1.2E-29 T 28-03-2018 CDW54_RS10535 b1c0129b078796d30b95bda7950846ea 238 SUPERFAMILY SSF52172 1 120 2.42E-33 T 28-03-2018 IPR011006 CheY-like superfamily CDW54_RS06220 8279961404f1e18889aefa596940f046 150 SUPERFAMILY SSF160515 3 129 7.06E-41 T 28-03-2018 CDW54_RS06220 8279961404f1e18889aefa596940f046 150 PIRSF PIRSF034303 1 150 8.4E-50 T 28-03-2018 IPR012543 Protein of unknown function DUF1694 CDW54_RS06220 8279961404f1e18889aefa596940f046 150 Gene3D G3DSA:3.30.1330.30 4 125 1.0E-39 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CDW54_RS06220 8279961404f1e18889aefa596940f046 150 Pfam PF07997 Protein of unknown function (DUF1694) 4 121 6.0E-41 T 28-03-2018 IPR012543 Protein of unknown function DUF1694 CDW54_RS02355 0c48b274c013a142541e6cff9eab1154 104 Gene3D G3DSA:3.30.1310.10 1 104 6.5E-31 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CDW54_RS02355 0c48b274c013a142541e6cff9eab1154 104 SUPERFAMILY SSF82607 8 100 6.54E-28 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CDW54_RS02355 0c48b274c013a142541e6cff9eab1154 104 Pfam PF02575 YbaB/EbfC DNA-binding family 12 101 2.6E-29 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CDW54_RS02355 0c48b274c013a142541e6cff9eab1154 104 PIRSF PIRSF004555 4 104 3.0E-31 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CDW54_RS02355 0c48b274c013a142541e6cff9eab1154 104 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 1 102 8.5E-26 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CDW54_RS02355 0c48b274c013a142541e6cff9eab1154 104 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 6 100 20.814 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CDW54_RS12020 3d60466965e06c4a8427fe395382c981 314 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 3 310 29.685 T 28-03-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 CDW54_RS12020 3d60466965e06c4a8427fe395382c981 314 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 247 267 - T 28-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CDW54_RS12020 3d60466965e06c4a8427fe395382c981 314 SUPERFAMILY SSF51395 2 310 1.16E-73 T 28-03-2018 CDW54_RS12020 3d60466965e06c4a8427fe395382c981 314 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 3 308 1.8E-54 T 28-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CDW54_RS12020 3d60466965e06c4a8427fe395382c981 314 PIRSF PIRSF000164 1 312 8.4E-73 T 28-03-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 CDW54_RS12020 3d60466965e06c4a8427fe395382c981 314 Pfam PF01180 Dihydroorotate dehydrogenase 3 295 1.1E-91 T 28-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CDW54_RS12020 3d60466965e06c4a8427fe395382c981 314 Gene3D G3DSA:3.20.20.70 1 313 1.0E-51 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDW54_RS08215 eb6c1be6a6e8f8e12014a93aa8b7ca8d 378 PIRSF PIRSF005572 1 378 1.9E-117 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CDW54_RS08215 eb6c1be6a6e8f8e12014a93aa8b7ca8d 378 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 193 212 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CDW54_RS08215 eb6c1be6a6e8f8e12014a93aa8b7ca8d 378 Gene3D G3DSA:3.40.640.10 12 241 1.6E-52 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDW54_RS08215 eb6c1be6a6e8f8e12014a93aa8b7ca8d 378 Pfam PF00266 Aminotransferase class-V 4 368 1.5E-77 T 28-03-2018 IPR000192 Aminotransferase class V domain CDW54_RS08215 eb6c1be6a6e8f8e12014a93aa8b7ca8d 378 Gene3D G3DSA:3.90.1150.10 242 378 1.7E-27 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDW54_RS08215 eb6c1be6a6e8f8e12014a93aa8b7ca8d 378 SUPERFAMILY SSF53383 3 377 1.9E-99 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDW54_RS12705 4e5564de9a33148b0dd5724008efc9ed 451 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 253 443 7.6E-60 T 28-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 CDW54_RS12705 4e5564de9a33148b0dd5724008efc9ed 451 Hamap MF_00564 Ribonuclease PH [rph]. 1 238 44.954 T 28-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 CDW54_RS12705 4e5564de9a33148b0dd5724008efc9ed 451 SUPERFAMILY SSF52972 247 444 9.42E-69 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CDW54_RS12705 4e5564de9a33148b0dd5724008efc9ed 451 ProSitePatterns PS01277 Ribonuclease PH signature. 116 128 - T 28-03-2018 IPR018336 Ribonuclease PH, conserved site CDW54_RS12705 4e5564de9a33148b0dd5724008efc9ed 451 SUPERFAMILY SSF55666 152 237 2.52E-21 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CDW54_RS12705 4e5564de9a33148b0dd5724008efc9ed 451 SUPERFAMILY SSF54211 1 182 2.08E-42 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CDW54_RS12705 4e5564de9a33148b0dd5724008efc9ed 451 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 2 237 7.3E-108 T 28-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 CDW54_RS12705 4e5564de9a33148b0dd5724008efc9ed 451 Pfam PF01138 3' exoribonuclease family, domain 1 10 139 2.5E-23 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CDW54_RS12705 4e5564de9a33148b0dd5724008efc9ed 451 Pfam PF03725 3' exoribonuclease family, domain 2 160 224 1.7E-9 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CDW54_RS12705 4e5564de9a33148b0dd5724008efc9ed 451 Gene3D G3DSA:3.90.950.10 244 447 6.4E-80 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CDW54_RS12705 4e5564de9a33148b0dd5724008efc9ed 451 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 252 445 50.278 T 28-03-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 CDW54_RS12705 4e5564de9a33148b0dd5724008efc9ed 451 Pfam PF01725 Ham1 family 254 440 7.2E-59 T 28-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 CDW54_RS12705 4e5564de9a33148b0dd5724008efc9ed 451 Gene3D G3DSA:3.30.230.70 1 243 2.2E-54 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CDW54_RS03460 9c6be13ea2f6b197915087d874aa88d9 341 SUPERFAMILY SSF56601 4 320 1.04E-69 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CDW54_RS03460 9c6be13ea2f6b197915087d874aa88d9 341 Pfam PF00144 Beta-lactamase 7 319 3.7E-49 T 28-03-2018 IPR001466 Beta-lactamase-related CDW54_RS03460 9c6be13ea2f6b197915087d874aa88d9 341 Gene3D G3DSA:3.40.710.10 1 333 3.5E-67 T 28-03-2018 CDW54_RS10255 de6a6ed4773d67e84d48f4ecd96e9de4 146 Gene3D G3DSA:1.10.4040.10 75 124 8.4E-4 T 28-03-2018 CDW54_RS10255 de6a6ed4773d67e84d48f4ecd96e9de4 146 Gene3D G3DSA:1.10.10.10 11 74 1.3E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS10255 de6a6ed4773d67e84d48f4ecd96e9de4 146 TIGRFAM TIGR02698 CopY_TcrY: copper transport repressor, CopY/TcrY family 9 136 2.2E-53 T 28-03-2018 IPR014071 Copper transport repressor CopY/TcrY CDW54_RS10255 de6a6ed4773d67e84d48f4ecd96e9de4 146 Pfam PF03965 Penicillinase repressor 10 124 2.5E-36 T 28-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CDW54_RS10255 de6a6ed4773d67e84d48f4ecd96e9de4 146 PIRSF PIRSF019455 2 135 6.4E-42 T 28-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CDW54_RS10255 de6a6ed4773d67e84d48f4ecd96e9de4 146 SUPERFAMILY SSF46785 8 125 1.14E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS07240 b171225db4dc856fc80d72fb749fdf5c 289 TIGRFAM TIGR03132 malonate_mdcB: triphosphoribosyl-dephospho-CoA synthase MdcB 12 273 3.2E-93 T 28-03-2018 IPR017555 Triphosphoribosyl-dephospho-CoA synthase GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 CDW54_RS07240 b171225db4dc856fc80d72fb749fdf5c 289 Hamap MF_01883 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase [mdcB]. 1 289 111.263 T 28-03-2018 IPR017555 Triphosphoribosyl-dephospho-CoA synthase GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 CDW54_RS07240 b171225db4dc856fc80d72fb749fdf5c 289 Pfam PF01874 ATP:dephospho-CoA triphosphoribosyl transferase 15 269 1.1E-66 T 28-03-2018 IPR002736 Triphosphoribosyl-dephospho-CoA protein GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 CDW54_RS11885 fa985ccd76cc4f57b4d4f4d26bb20974 204 SUPERFAMILY SSF50475 4 199 4.22E-42 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CDW54_RS11885 fa985ccd76cc4f57b4d4f4d26bb20974 204 Gene3D G3DSA:2.30.110.10 2 201 6.7E-45 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CDW54_RS11885 fa985ccd76cc4f57b4d4f4d26bb20974 204 SMART SM00903 20 170 1.5E-17 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CDW54_RS11885 fa985ccd76cc4f57b4d4f4d26bb20974 204 Pfam PF01613 Flavin reductase like domain 23 167 8.8E-19 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CDW54_RS10865 8f50f203a72222483629f9b33fc881f8 157 SUPERFAMILY SSF75420 3 85 2.75E-28 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CDW54_RS10865 8f50f203a72222483629f9b33fc881f8 157 Pfam PF17384 RimP C-terminal SH3 domain 88 157 4.0E-20 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal CDW54_RS10865 8f50f203a72222483629f9b33fc881f8 157 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 6 157 24.611 T 28-03-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 CDW54_RS10865 8f50f203a72222483629f9b33fc881f8 157 Gene3D G3DSA:2.30.30.180 89 155 1.1E-22 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal CDW54_RS10865 8f50f203a72222483629f9b33fc881f8 157 Pfam PF02576 RimP N-terminal domain 11 85 5.3E-28 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CDW54_RS10865 8f50f203a72222483629f9b33fc881f8 157 SUPERFAMILY SSF74942 86 157 3.14E-21 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal CDW54_RS10865 8f50f203a72222483629f9b33fc881f8 157 Gene3D G3DSA:3.30.300.70 1 82 4.1E-26 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CDW54_RS07735 3fdfebbd861a03bbf7ac571b9768e0fc 457 Pfam PF02378 Phosphotransferase system, EIIC 110 392 1.2E-32 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CDW54_RS07735 3fdfebbd861a03bbf7ac571b9768e0fc 457 Gene3D G3DSA:3.30.1360.60 13 90 1.1E-12 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CDW54_RS07735 3fdfebbd861a03bbf7ac571b9768e0fc 457 Pfam PF00367 phosphotransferase system, EIIB 19 44 1.1E-9 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CDW54_RS07735 3fdfebbd861a03bbf7ac571b9768e0fc 457 SUPERFAMILY SSF55604 15 90 5.75E-12 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CDW54_RS07110 5537815ba5afa59e906a38dcc3384c20 106 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 24 99 2.0E-5 T 28-03-2018 CDW54_RS07110 5537815ba5afa59e906a38dcc3384c20 106 Pfam PF14145 YrhK-like protein 32 88 1.2E-14 T 28-03-2018 IPR025424 YrhK domain CDW54_RS10025 0ffb94b18e7b72741d71746b24dfa4bc 691 SUPERFAMILY SSF109604 337 492 2.3E-19 T 28-03-2018 CDW54_RS10025 0ffb94b18e7b72741d71746b24dfa4bc 691 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 3 688 8.0E-239 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CDW54_RS10025 0ffb94b18e7b72741d71746b24dfa4bc 691 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 5 554 4.3E-210 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CDW54_RS10025 0ffb94b18e7b72741d71746b24dfa4bc 691 Gene3D G3DSA:1.10.730.10 583 682 1.8E-6 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDW54_RS10025 0ffb94b18e7b72741d71746b24dfa4bc 691 Gene3D G3DSA:1.10.3210.10 307 465 0.0071 T 28-03-2018 CDW54_RS10025 0ffb94b18e7b72741d71746b24dfa4bc 691 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 2 688 27.522 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CDW54_RS10025 0ffb94b18e7b72741d71746b24dfa4bc 691 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 242 257 7.2E-35 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CDW54_RS10025 0ffb94b18e7b72741d71746b24dfa4bc 691 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 6 19 7.2E-35 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CDW54_RS10025 0ffb94b18e7b72741d71746b24dfa4bc 691 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 393 412 7.2E-35 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CDW54_RS10025 0ffb94b18e7b72741d71746b24dfa4bc 691 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 49 61 7.2E-35 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CDW54_RS10025 0ffb94b18e7b72741d71746b24dfa4bc 691 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 314 330 7.2E-35 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CDW54_RS04565 0457a80cbe7d176d12027ea30ce1eedd 672 SUPERFAMILY SSF54106 488 532 4.19E-12 T 28-03-2018 IPR018392 LysM domain CDW54_RS04565 0457a80cbe7d176d12027ea30ce1eedd 672 Gene3D G3DSA:3.10.350.10 625 672 9.3E-16 T 28-03-2018 CDW54_RS04565 0457a80cbe7d176d12027ea30ce1eedd 672 SUPERFAMILY SSF54106 333 376 7.46E-12 T 28-03-2018 IPR018392 LysM domain CDW54_RS04565 0457a80cbe7d176d12027ea30ce1eedd 672 SUPERFAMILY SSF54106 255 299 1.57E-13 T 28-03-2018 IPR018392 LysM domain CDW54_RS04565 0457a80cbe7d176d12027ea30ce1eedd 672 SUPERFAMILY SSF54106 566 610 8.37E-12 T 28-03-2018 IPR018392 LysM domain CDW54_RS04565 0457a80cbe7d176d12027ea30ce1eedd 672 SMART SM00257 628 671 1.3E-15 T 28-03-2018 IPR018392 LysM domain CDW54_RS04565 0457a80cbe7d176d12027ea30ce1eedd 672 SMART SM00257 568 611 9.9E-14 T 28-03-2018 IPR018392 LysM domain CDW54_RS04565 0457a80cbe7d176d12027ea30ce1eedd 672 SMART SM00257 256 299 1.1E-17 T 28-03-2018 IPR018392 LysM domain CDW54_RS04565 0457a80cbe7d176d12027ea30ce1eedd 672 SMART SM00257 489 532 5.6E-16 T 28-03-2018 IPR018392 LysM domain CDW54_RS04565 0457a80cbe7d176d12027ea30ce1eedd 672 SMART SM00257 333 376 1.0E-15 T 28-03-2018 IPR018392 LysM domain CDW54_RS04565 0457a80cbe7d176d12027ea30ce1eedd 672 SMART SM00257 412 455 3.6E-16 T 28-03-2018 IPR018392 LysM domain CDW54_RS04565 0457a80cbe7d176d12027ea30ce1eedd 672 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 72 209 2.8E-18 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CDW54_RS04565 0457a80cbe7d176d12027ea30ce1eedd 672 Gene3D G3DSA:3.10.350.10 249 317 5.1E-19 T 28-03-2018 CDW54_RS04565 0457a80cbe7d176d12027ea30ce1eedd 672 Gene3D G3DSA:3.10.350.10 326 406 2.6E-16 T 28-03-2018 CDW54_RS04565 0457a80cbe7d176d12027ea30ce1eedd 672 Gene3D G3DSA:3.10.350.10 482 562 9.2E-18 T 28-03-2018 CDW54_RS04565 0457a80cbe7d176d12027ea30ce1eedd 672 Gene3D G3DSA:3.10.350.10 563 624 4.3E-17 T 28-03-2018 CDW54_RS04565 0457a80cbe7d176d12027ea30ce1eedd 672 Gene3D G3DSA:3.10.350.10 407 477 9.9E-18 T 28-03-2018 CDW54_RS04565 0457a80cbe7d176d12027ea30ce1eedd 672 SUPERFAMILY SSF54106 411 455 1.44E-12 T 28-03-2018 IPR018392 LysM domain CDW54_RS04565 0457a80cbe7d176d12027ea30ce1eedd 672 SMART SM00047 55 214 5.3E-80 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CDW54_RS04565 0457a80cbe7d176d12027ea30ce1eedd 672 Gene3D G3DSA:1.10.530.10 59 214 2.8E-36 T 28-03-2018 CDW54_RS04565 0457a80cbe7d176d12027ea30ce1eedd 672 Pfam PF01476 LysM domain 413 454 4.5E-16 T 28-03-2018 IPR018392 LysM domain CDW54_RS04565 0457a80cbe7d176d12027ea30ce1eedd 672 Pfam PF01476 LysM domain 629 670 3.2E-15 T 28-03-2018 IPR018392 LysM domain CDW54_RS04565 0457a80cbe7d176d12027ea30ce1eedd 672 Pfam PF01476 LysM domain 334 375 4.7E-15 T 28-03-2018 IPR018392 LysM domain CDW54_RS04565 0457a80cbe7d176d12027ea30ce1eedd 672 Pfam PF01476 LysM domain 257 298 1.7E-17 T 28-03-2018 IPR018392 LysM domain CDW54_RS04565 0457a80cbe7d176d12027ea30ce1eedd 672 Pfam PF01476 LysM domain 569 610 1.8E-14 T 28-03-2018 IPR018392 LysM domain CDW54_RS04565 0457a80cbe7d176d12027ea30ce1eedd 672 Pfam PF01476 LysM domain 490 531 1.7E-15 T 28-03-2018 IPR018392 LysM domain CDW54_RS04565 0457a80cbe7d176d12027ea30ce1eedd 672 SUPERFAMILY SSF54106 627 670 3.01E-12 T 28-03-2018 IPR018392 LysM domain CDW54_RS09170 2db811fcf4b2d0e2c60de0ed30183efd 361 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 36 321 2.6E-110 T 28-03-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 CDW54_RS09170 2db811fcf4b2d0e2c60de0ed30183efd 361 Pfam PF08402 TOBE domain 274 343 7.4E-8 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CDW54_RS09170 2db811fcf4b2d0e2c60de0ed30183efd 361 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS09170 2db811fcf4b2d0e2c60de0ed30183efd 361 Pfam PF00005 ABC transporter 21 163 6.0E-37 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS09170 2db811fcf4b2d0e2c60de0ed30183efd 361 Gene3D G3DSA:3.40.50.300 1 244 4.5E-77 T 28-03-2018 CDW54_RS09170 2db811fcf4b2d0e2c60de0ed30183efd 361 SUPERFAMILY SSF50331 238 343 4.7E-11 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CDW54_RS09170 2db811fcf4b2d0e2c60de0ed30183efd 361 SMART SM00382 30 213 4.2E-19 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS09170 2db811fcf4b2d0e2c60de0ed30183efd 361 Gene3D G3DSA:2.40.50.100 291 351 0.31 T 28-03-2018 CDW54_RS09170 2db811fcf4b2d0e2c60de0ed30183efd 361 SUPERFAMILY SSF52540 5 243 6.1E-86 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS03290 2fa92c3c0dbbe77f9465dbc20171235b 386 SUPERFAMILY SSF49478 11 96 1.33E-30 T 28-03-2018 CDW54_RS03290 2fa92c3c0dbbe77f9465dbc20171235b 386 Gene3D G3DSA:2.60.120.170 266 312 0.029 T 28-03-2018 CDW54_RS03290 2fa92c3c0dbbe77f9465dbc20171235b 386 Gene3D G3DSA:2.60.40.10 181 265 2.1E-32 T 28-03-2018 IPR013783 Immunoglobulin-like fold CDW54_RS03290 2fa92c3c0dbbe77f9465dbc20171235b 386 Gene3D G3DSA:2.60.40.10 1 89 4.9E-31 T 28-03-2018 IPR013783 Immunoglobulin-like fold CDW54_RS03290 2fa92c3c0dbbe77f9465dbc20171235b 386 Gene3D G3DSA:2.60.40.10 90 180 6.1E-28 T 28-03-2018 IPR013783 Immunoglobulin-like fold CDW54_RS03290 2fa92c3c0dbbe77f9465dbc20171235b 386 SUPERFAMILY SSF49478 99 191 1.24E-23 T 28-03-2018 CDW54_RS03290 2fa92c3c0dbbe77f9465dbc20171235b 386 Pfam PF05738 Cna protein B-type domain 103 191 1.3E-24 T 28-03-2018 IPR008454 Collagen-binding surface protein Cna-like, B-type domain CDW54_RS03290 2fa92c3c0dbbe77f9465dbc20171235b 386 Pfam PF05738 Cna protein B-type domain 199 280 2.4E-26 T 28-03-2018 IPR008454 Collagen-binding surface protein Cna-like, B-type domain CDW54_RS03290 2fa92c3c0dbbe77f9465dbc20171235b 386 Pfam PF05738 Cna protein B-type domain 12 93 2.4E-26 T 28-03-2018 IPR008454 Collagen-binding surface protein Cna-like, B-type domain CDW54_RS03290 2fa92c3c0dbbe77f9465dbc20171235b 386 SUPERFAMILY SSF49478 198 283 1.33E-30 T 28-03-2018 CDW54_RS03290 2fa92c3c0dbbe77f9465dbc20171235b 386 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 353 385 2.0E-5 T 28-03-2018 CDW54_RS00400 c43249af3c6f63f6119f087f1f8457bf 479 Pfam PF13537 Glutamine amidotransferase domain 92 211 1.9E-20 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain CDW54_RS00400 c43249af3c6f63f6119f087f1f8457bf 479 Pfam PF00156 Phosphoribosyl transferase domain 282 383 4.5E-10 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CDW54_RS00400 c43249af3c6f63f6119f087f1f8457bf 479 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 12 458 1.6E-159 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CDW54_RS00400 c43249af3c6f63f6119f087f1f8457bf 479 Gene3D G3DSA:3.40.50.2020 224 391 7.1E-38 T 28-03-2018 CDW54_RS00400 c43249af3c6f63f6119f087f1f8457bf 479 Gene3D G3DSA:3.60.20.10 12 223 1.3E-54 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CDW54_RS00400 c43249af3c6f63f6119f087f1f8457bf 479 PIRSF PIRSF000485 8 475 5.7E-179 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CDW54_RS00400 c43249af3c6f63f6119f087f1f8457bf 479 SUPERFAMILY SSF56235 12 265 3.0E-67 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CDW54_RS00400 c43249af3c6f63f6119f087f1f8457bf 479 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 11 457 46.677 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CDW54_RS00400 c43249af3c6f63f6119f087f1f8457bf 479 SUPERFAMILY SSF53271 248 465 7.47E-75 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CDW54_RS01565 b536d9f4f46139fe891504a80627d9e8 74 Pfam PF00550 Phosphopantetheine attachment site 4 69 7.9E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDW54_RS01565 b536d9f4f46139fe891504a80627d9e8 74 Hamap MF_01217 Acyl carrier protein [acpP]. 1 73 17.338 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CDW54_RS01565 b536d9f4f46139fe891504a80627d9e8 74 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 33 72 7.0E-15 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CDW54_RS01565 b536d9f4f46139fe891504a80627d9e8 74 Gene3D G3DSA:1.10.1200.10 1 74 8.2E-20 T 28-03-2018 CDW54_RS01565 b536d9f4f46139fe891504a80627d9e8 74 SUPERFAMILY SSF47336 2 72 8.24E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDW54_RS12300 eaca653a2bbe5b7ae977cd1fb9ca30cc 256 Pfam PF00005 ABC transporter 25 180 1.9E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS12300 eaca653a2bbe5b7ae977cd1fb9ca30cc 256 SMART SM00382 34 229 2.5E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS12300 eaca653a2bbe5b7ae977cd1fb9ca30cc 256 Gene3D G3DSA:3.40.50.300 1 243 9.7E-52 T 28-03-2018 CDW54_RS12300 eaca653a2bbe5b7ae977cd1fb9ca30cc 256 SUPERFAMILY SSF52540 5 236 1.07E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS12300 eaca653a2bbe5b7ae977cd1fb9ca30cc 256 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS04480 caee0b8d6c54e993a123bc7a73ba062c 450 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 13 439 4.2E-94 T 28-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 CDW54_RS04480 caee0b8d6c54e993a123bc7a73ba062c 450 Pfam PF02378 Phosphotransferase system, EIIC 30 364 5.3E-53 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CDW54_RS04480 caee0b8d6c54e993a123bc7a73ba062c 450 PIRSF PIRSF006351 1 447 1.5E-126 T 28-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 CDW54_RS12030 47807a10b0ab251d4a738b3c036e4ebd 278 SUPERFAMILY SSF53850 1 263 1.11E-55 T 28-03-2018 CDW54_RS12030 47807a10b0ab251d4a738b3c036e4ebd 278 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 63 76 - T 28-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 CDW54_RS12030 47807a10b0ab251d4a738b3c036e4ebd 278 Gene3D G3DSA:3.40.190.10 1 162 7.8E-32 T 28-03-2018 CDW54_RS12030 47807a10b0ab251d4a738b3c036e4ebd 278 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 41 261 8.3E-52 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CDW54_RS12030 47807a10b0ab251d4a738b3c036e4ebd 278 SMART SM00062 40 263 1.3E-59 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CDW54_RS12030 47807a10b0ab251d4a738b3c036e4ebd 278 Gene3D G3DSA:3.40.190.10 163 268 2.2E-14 T 28-03-2018 CDW54_RS05635 1aeab480bfa783e71ac40557530fbe76 465 Pfam PF12631 MnmE helical domain 133 462 3.2E-58 T 28-03-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 CDW54_RS05635 1aeab480bfa783e71ac40557530fbe76 465 Pfam PF10396 GTP-binding protein TrmE N-terminus 10 130 1.8E-42 T 28-03-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 CDW54_RS05635 1aeab480bfa783e71ac40557530fbe76 465 SUPERFAMILY SSF52540 208 381 3.56E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS05635 1aeab480bfa783e71ac40557530fbe76 465 SUPERFAMILY SSF52540 84 173 3.56E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS05635 1aeab480bfa783e71ac40557530fbe76 465 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 16 465 1.3E-134 T 28-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 CDW54_RS05635 1aeab480bfa783e71ac40557530fbe76 465 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 9 465 34.475 T 28-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 CDW54_RS05635 1aeab480bfa783e71ac40557530fbe76 465 Gene3D G3DSA:3.30.1360.120 1 131 4.8E-46 T 28-03-2018 CDW54_RS05635 1aeab480bfa783e71ac40557530fbe76 465 Gene3D G3DSA:1.20.120.430 132 292 1.2E-30 T 28-03-2018 CDW54_RS05635 1aeab480bfa783e71ac40557530fbe76 465 Pfam PF01926 50S ribosome-binding GTPase 231 342 3.3E-25 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CDW54_RS05635 1aeab480bfa783e71ac40557530fbe76 465 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 231 377 1.5E-27 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CDW54_RS05635 1aeab480bfa783e71ac40557530fbe76 465 Gene3D G3DSA:1.20.120.430 293 465 4.4E-32 T 28-03-2018 CDW54_RS09920 73751059f2b465e31971df41511f94bc 283 SUPERFAMILY SSF63520 172 276 1.44E-23 T 28-03-2018 IPR011608 PRD domain GO:0006355 CDW54_RS09920 73751059f2b465e31971df41511f94bc 283 Pfam PF03123 CAT RNA binding domain 1 53 2.1E-21 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CDW54_RS09920 73751059f2b465e31971df41511f94bc 283 Pfam PF00874 PRD domain 181 273 5.0E-18 T 28-03-2018 IPR011608 PRD domain GO:0006355 CDW54_RS09920 73751059f2b465e31971df41511f94bc 283 Pfam PF00874 PRD domain 76 163 1.4E-24 T 28-03-2018 IPR011608 PRD domain GO:0006355 CDW54_RS09920 73751059f2b465e31971df41511f94bc 283 SUPERFAMILY SSF63520 60 164 1.44E-29 T 28-03-2018 IPR011608 PRD domain GO:0006355 CDW54_RS09920 73751059f2b465e31971df41511f94bc 283 Gene3D G3DSA:1.10.1790.10 165 279 4.8E-23 T 28-03-2018 IPR011608 PRD domain GO:0006355 CDW54_RS09920 73751059f2b465e31971df41511f94bc 283 Gene3D G3DSA:1.10.1790.10 54 164 4.7E-27 T 28-03-2018 IPR011608 PRD domain GO:0006355 CDW54_RS09920 73751059f2b465e31971df41511f94bc 283 Gene3D G3DSA:2.30.24.10 1 53 8.7E-22 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CDW54_RS09920 73751059f2b465e31971df41511f94bc 283 SMART SM01061 1 59 2.4E-24 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CDW54_RS09920 73751059f2b465e31971df41511f94bc 283 SUPERFAMILY SSF50151 1 53 4.05E-16 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CDW54_RS10900 8a39434788d6483c39e1406ec066bd55 787 SUPERFAMILY SSF52518 374 589 2.16E-31 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CDW54_RS10900 8a39434788d6483c39e1406ec066bd55 787 Pfam PF03894 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 397 573 2.8E-82 T 28-03-2018 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 CDW54_RS10900 8a39434788d6483c39e1406ec066bd55 787 Pfam PF09364 XFP N-terminal domain 5 382 9.5E-180 T 28-03-2018 IPR018970 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, N-terminal CDW54_RS10900 8a39434788d6483c39e1406ec066bd55 787 Gene3D G3DSA:3.40.50.920 605 784 1.7E-67 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CDW54_RS10900 8a39434788d6483c39e1406ec066bd55 787 ProSitePatterns PS60002 Phosphoketolase signature 1. 140 146 - T 28-03-2018 IPR019790 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, conserved site GO:0005975|GO:0016832 CDW54_RS10900 8a39434788d6483c39e1406ec066bd55 787 Gene3D G3DSA:3.40.50.970 1 376 5.2E-80 T 28-03-2018 CDW54_RS10900 8a39434788d6483c39e1406ec066bd55 787 Hamap MF_01403 Probable phosphoketolase. 1 784 37.943 T 28-03-2018 IPR023962 Probable phosphoketolase CDW54_RS10900 8a39434788d6483c39e1406ec066bd55 787 SUPERFAMILY SSF52518 2 366 2.05E-71 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CDW54_RS10900 8a39434788d6483c39e1406ec066bd55 787 Pfam PF09363 XFP C-terminal domain 584 782 1.0E-77 T 28-03-2018 IPR018969 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, C-terminal GO:0005975|GO:0016832 CDW54_RS10900 8a39434788d6483c39e1406ec066bd55 787 PIRSF PIRSF017245 1 784 0.0 T 28-03-2018 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 CDW54_RS10900 8a39434788d6483c39e1406ec066bd55 787 Gene3D G3DSA:3.40.50.970 385 599 2.9E-31 T 28-03-2018 CDW54_RS10900 8a39434788d6483c39e1406ec066bd55 787 ProSitePatterns PS60003 Phosphoketolase signature 2. 153 171 - T 28-03-2018 IPR019789 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, thiamine diphosphate binding site GO:0005975|GO:0016832 CDW54_RS06760 1a9cc8db01cbcfbbffb91fe889caa818 174 Gene3D G3DSA:3.10.20.80 4 80 4.9E-29 T 28-03-2018 CDW54_RS06760 1a9cc8db01cbcfbbffb91fe889caa818 174 Gene3D G3DSA:3.30.110.10 81 174 1.3E-34 T 28-03-2018 CDW54_RS06760 1a9cc8db01cbcfbbffb91fe889caa818 174 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 9 171 5.7E-71 T 28-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CDW54_RS06760 1a9cc8db01cbcfbbffb91fe889caa818 174 ProSitePatterns PS00938 Initiation factor 3 signature. 60 73 - T 28-03-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 CDW54_RS06760 1a9cc8db01cbcfbbffb91fe889caa818 174 SUPERFAMILY SSF55200 84 172 2.49E-32 T 28-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CDW54_RS06760 1a9cc8db01cbcfbbffb91fe889caa818 174 SUPERFAMILY SSF54364 7 80 4.45E-28 T 28-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CDW54_RS06760 1a9cc8db01cbcfbbffb91fe889caa818 174 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 85 170 3.4E-37 T 28-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CDW54_RS06760 1a9cc8db01cbcfbbffb91fe889caa818 174 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 9 78 5.7E-30 T 28-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CDW54_RS06760 1a9cc8db01cbcfbbffb91fe889caa818 174 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 3 172 30.298 T 28-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CDW54_RS05420 407c692b8aa05c3aa97a7e7acc0d9120 367 PIRSF PIRSF006268 13 355 1.9E-111 T 28-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 CDW54_RS05420 407c692b8aa05c3aa97a7e7acc0d9120 367 Gene3D G3DSA:3.10.520.10 30 350 3.3E-54 T 28-03-2018 CDW54_RS05420 407c692b8aa05c3aa97a7e7acc0d9120 367 Pfam PF02424 ApbE family 52 333 7.2E-84 T 28-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 CDW54_RS05420 407c692b8aa05c3aa97a7e7acc0d9120 367 SUPERFAMILY SSF143631 44 350 2.88E-92 T 28-03-2018 IPR003374 ApbE-like domain CDW54_RS07830 5c637da7808d6d35fc40590c07a9d450 728 Gene3D G3DSA:3.40.50.300 356 728 4.9E-46 T 28-03-2018 CDW54_RS07830 5c637da7808d6d35fc40590c07a9d450 728 Gene3D G3DSA:3.40.50.300 73 355 1.7E-52 T 28-03-2018 CDW54_RS07830 5c637da7808d6d35fc40590c07a9d450 728 SUPERFAMILY SSF52540 524 720 3.73E-102 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS07830 5c637da7808d6d35fc40590c07a9d450 728 SUPERFAMILY SSF52540 72 494 3.73E-102 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS07830 5c637da7808d6d35fc40590c07a9d450 728 Pfam PF13361 UvrD-like helicase C-terminal domain 492 701 2.4E-20 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CDW54_RS07830 5c637da7808d6d35fc40590c07a9d450 728 Pfam PF13361 UvrD-like helicase C-terminal domain 362 459 4.3E-11 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CDW54_RS07830 5c637da7808d6d35fc40590c07a9d450 728 Pfam PF00580 UvrD/REP helicase N-terminal domain 76 355 5.9E-52 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CDW54_RS02805 77bd71a2555148a3bd3f6a63a8f84a23 317 Gene3D G3DSA:1.10.10.60 3 48 1.2E-4 T 28-03-2018 CDW54_RS02805 77bd71a2555148a3bd3f6a63a8f84a23 317 Gene3D G3DSA:1.10.10.60 62 119 0.16 T 28-03-2018 CDW54_RS02805 77bd71a2555148a3bd3f6a63a8f84a23 317 SUPERFAMILY SSF53098 160 309 1.04E-16 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS02805 77bd71a2555148a3bd3f6a63a8f84a23 317 Gene3D G3DSA:3.30.420.10 156 314 9.8E-18 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS00955 6383dd23728df32e4fcc97e0f56230af 446 Gene3D G3DSA:3.30.70.360 259 351 9.0E-18 T 28-03-2018 CDW54_RS00955 6383dd23728df32e4fcc97e0f56230af 446 TIGRFAM TIGR01887 dipeptidaselike: putative dipeptidase 12 440 6.9E-133 T 28-03-2018 IPR010964 Peptidase M20A, peptidase V-related GO:0008270|GO:0016805 CDW54_RS00955 6383dd23728df32e4fcc97e0f56230af 446 Gene3D G3DSA:3.40.630.10 3 192 7.4E-28 T 28-03-2018 CDW54_RS00955 6383dd23728df32e4fcc97e0f56230af 446 Pfam PF07687 Peptidase dimerisation domain 244 350 1.7E-4 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CDW54_RS00955 6383dd23728df32e4fcc97e0f56230af 446 Pfam PF01546 Peptidase family M20/M25/M40 84 441 2.7E-32 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CDW54_RS00955 6383dd23728df32e4fcc97e0f56230af 446 SUPERFAMILY SSF53187 362 444 3.83E-64 T 28-03-2018 CDW54_RS00955 6383dd23728df32e4fcc97e0f56230af 446 SUPERFAMILY SSF53187 7 186 3.83E-64 T 28-03-2018 CDW54_RS00955 6383dd23728df32e4fcc97e0f56230af 446 SUPERFAMILY SSF55031 186 358 1.97E-33 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CDW54_RS03600 969a7ba83c90503f8874b274764dc254 274 Gene3D G3DSA:3.40.50.620 2 274 1.0E-59 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDW54_RS03600 969a7ba83c90503f8874b274764dc254 274 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 17 268 30.246 T 28-03-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 CDW54_RS03600 969a7ba83c90503f8874b274764dc254 274 TIGRFAM TIGR00552 nadE: NAD+ synthetase 17 274 9.1E-74 T 28-03-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 CDW54_RS03600 969a7ba83c90503f8874b274764dc254 274 SUPERFAMILY SSF52402 3 273 1.37E-82 T 28-03-2018 CDW54_RS03600 969a7ba83c90503f8874b274764dc254 274 Pfam PF02540 NAD synthase 23 265 1.2E-68 T 28-03-2018 IPR022310 NAD/GMP synthase CDW54_RS10795 c6d554f2574db469d395be05790e177d 563 Hamap MF_00123 Arginine--tRNA ligase [argS]. 5 563 25.808 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CDW54_RS10795 c6d554f2574db469d395be05790e177d 563 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 11 563 1.4E-145 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CDW54_RS10795 c6d554f2574db469d395be05790e177d 563 Gene3D G3DSA:1.10.730.10 431 563 1.1E-39 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDW54_RS10795 c6d554f2574db469d395be05790e177d 563 SUPERFAMILY SSF52374 108 444 2.96E-95 T 28-03-2018 CDW54_RS10795 c6d554f2574db469d395be05790e177d 563 SMART SM00836 450 563 1.3E-32 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CDW54_RS10795 c6d554f2574db469d395be05790e177d 563 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 5 84 4.5E-18 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CDW54_RS10795 c6d554f2574db469d395be05790e177d 563 SUPERFAMILY SSF55190 1 105 5.89E-27 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CDW54_RS10795 c6d554f2574db469d395be05790e177d 563 SUPERFAMILY SSF47323 444 563 3.14E-30 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDW54_RS10795 c6d554f2574db469d395be05790e177d 563 Gene3D G3DSA:3.30.1360.70 2 105 9.6E-27 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CDW54_RS10795 c6d554f2574db469d395be05790e177d 563 Pfam PF05746 DALR anticodon binding domain 450 563 2.7E-27 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CDW54_RS10795 c6d554f2574db469d395be05790e177d 563 SMART SM01016 5 84 1.2E-25 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CDW54_RS10795 c6d554f2574db469d395be05790e177d 563 Gene3D G3DSA:3.40.50.620 106 430 1.3E-56 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDW54_RS10795 c6d554f2574db469d395be05790e177d 563 Pfam PF00750 tRNA synthetases class I (R) 95 435 1.4E-96 T 28-03-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 CDW54_RS10795 c6d554f2574db469d395be05790e177d 563 PRINTS PR01038 Arginyl-tRNA synthetase signature 297 318 7.4E-19 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CDW54_RS10795 c6d554f2574db469d395be05790e177d 563 PRINTS PR01038 Arginyl-tRNA synthetase signature 114 129 7.4E-19 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CDW54_RS10795 c6d554f2574db469d395be05790e177d 563 PRINTS PR01038 Arginyl-tRNA synthetase signature 153 166 7.4E-19 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CDW54_RS10795 c6d554f2574db469d395be05790e177d 563 PRINTS PR01038 Arginyl-tRNA synthetase signature 129 145 7.4E-19 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CDW54_RS11920 21c1b24a630deb398f378812d0fc07ec 116 PIRSF PIRSF033199 1 116 2.7E-57 T 28-03-2018 IPR014580 Uncharacterised conserved protein UCP033199 CDW54_RS11920 21c1b24a630deb398f378812d0fc07ec 116 Gene3D G3DSA:1.10.8.290 3 116 9.2E-56 T 28-03-2018 IPR023204 SP1917 domain CDW54_RS11920 21c1b24a630deb398f378812d0fc07ec 116 Pfam PF09966 Uncharacterized protein conserved in bacteria (DUF2200) 5 115 7.9E-54 T 28-03-2018 IPR014580 Uncharacterised conserved protein UCP033199 CDW54_RS10610 e6846d97b4bf2bf5b6119356e0f25f52 599 SUPERFAMILY SSF51695 347 576 3.66E-55 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CDW54_RS10610 e6846d97b4bf2bf5b6119356e0f25f52 599 Gene3D G3DSA:3.20.20.190 334 595 1.5E-49 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CDW54_RS10610 e6846d97b4bf2bf5b6119356e0f25f52 599 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 353 572 5.9E-27 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CDW54_RS10610 e6846d97b4bf2bf5b6119356e0f25f52 599 Pfam PF10110 Membrane domain of glycerophosphoryl diester phosphodiesterase 10 328 8.1E-97 T 28-03-2018 IPR018476 Glycerophosphoryl diester phosphodiesterase, membrane domain CDW54_RS11780 827d6c6f0816356dba6ec700eacc1833 297 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 61 292 3.2E-51 T 28-03-2018 CDW54_RS11780 827d6c6f0816356dba6ec700eacc1833 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 191 1.5E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS11780 827d6c6f0816356dba6ec700eacc1833 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 239 1.5E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS11780 827d6c6f0816356dba6ec700eacc1833 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 140 1.5E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS11780 827d6c6f0816356dba6ec700eacc1833 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 220 1.5E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS11780 827d6c6f0816356dba6ec700eacc1833 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 53 70 1.5E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS11780 827d6c6f0816356dba6ec700eacc1833 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 257 277 1.5E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS11780 827d6c6f0816356dba6ec700eacc1833 297 SUPERFAMILY SSF51735 50 293 2.22E-68 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS11780 827d6c6f0816356dba6ec700eacc1833 297 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 201 220 1.8E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS11780 827d6c6f0816356dba6ec700eacc1833 297 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 140 1.8E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS11780 827d6c6f0816356dba6ec700eacc1833 297 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 181 189 1.8E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS11780 827d6c6f0816356dba6ec700eacc1833 297 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 188 216 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CDW54_RS11780 827d6c6f0816356dba6ec700eacc1833 297 Gene3D G3DSA:3.40.50.720 4 296 4.9E-66 T 28-03-2018 CDW54_RS11375 dbb92534fb6321e9d008040d8e7a81e4 122 Gene3D G3DSA:3.10.180.10 6 122 3.9E-12 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDW54_RS11375 dbb92534fb6321e9d008040d8e7a81e4 122 SUPERFAMILY SSF54593 8 120 5.23E-14 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDW54_RS09685 b712dcb18e42b4fe38cdf75a4b0ffe75 98 SMART SM01234 1 68 5.6E-45 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CDW54_RS09685 b712dcb18e42b4fe38cdf75a4b0ffe75 98 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 5 71 1.3E-31 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CDW54_RS09685 b712dcb18e42b4fe38cdf75a4b0ffe75 98 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 1 69 24.84 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CDW54_RS09685 b712dcb18e42b4fe38cdf75a4b0ffe75 98 Pfam PF01809 Haemolytic domain 2 68 5.6E-30 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CDW54_RS09685 b712dcb18e42b4fe38cdf75a4b0ffe75 98 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 16 68 1.0E-25 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CDW54_RS05350 c8a9d129c700a5de0b6d27835bacbdcf 1208 Gene3D G3DSA:2.40.50.100 679 750 2.5E-26 T 28-03-2018 CDW54_RS05350 c8a9d129c700a5de0b6d27835bacbdcf 1208 SUPERFAMILY SSF64484 376 1156 0.0 T 28-03-2018 CDW54_RS05350 c8a9d129c700a5de0b6d27835bacbdcf 1208 SUPERFAMILY SSF64484 16 296 0.0 T 28-03-2018 CDW54_RS05350 c8a9d129c700a5de0b6d27835bacbdcf 1208 Pfam PF10385 RNA polymerase beta subunit external 1 domain 554 621 1.6E-24 T 28-03-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDW54_RS05350 c8a9d129c700a5de0b6d27835bacbdcf 1208 Pfam PF04563 RNA polymerase beta subunit 31 461 9.2E-28 T 28-03-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDW54_RS05350 c8a9d129c700a5de0b6d27835bacbdcf 1208 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 18 1146 12.504 T 28-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDW54_RS05350 c8a9d129c700a5de0b6d27835bacbdcf 1208 Gene3D G3DSA:3.90.1100.10 611 678 2.8E-13 T 28-03-2018 CDW54_RS05350 c8a9d129c700a5de0b6d27835bacbdcf 1208 Gene3D G3DSA:3.90.1100.10 23 252 9.1E-59 T 28-03-2018 CDW54_RS05350 c8a9d129c700a5de0b6d27835bacbdcf 1208 Gene3D G3DSA:3.90.1100.10 306 610 5.6E-81 T 28-03-2018 CDW54_RS05350 c8a9d129c700a5de0b6d27835bacbdcf 1208 Pfam PF04560 RNA polymerase Rpb2, domain 7 1070 1144 2.1E-26 T 28-03-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDW54_RS05350 c8a9d129c700a5de0b6d27835bacbdcf 1208 Pfam PF00562 RNA polymerase Rpb2, domain 6 683 1068 2.5E-163 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDW54_RS05350 c8a9d129c700a5de0b6d27835bacbdcf 1208 Gene3D G3DSA:2.40.270.10 751 847 2.6E-11 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDW54_RS05350 c8a9d129c700a5de0b6d27835bacbdcf 1208 ProSitePatterns PS01166 RNA polymerases beta chain signature. 921 933 - T 28-03-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDW54_RS05350 c8a9d129c700a5de0b6d27835bacbdcf 1208 Gene3D G3DSA:3.90.1800.10 1071 1116 1.2E-11 T 28-03-2018 CDW54_RS05350 c8a9d129c700a5de0b6d27835bacbdcf 1208 Pfam PF04565 RNA polymerase Rpb2, domain 3 476 544 1.3E-29 T 28-03-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDW54_RS05350 c8a9d129c700a5de0b6d27835bacbdcf 1208 Pfam PF04561 RNA polymerase Rpb2, domain 2 143 291 8.5E-21 T 28-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDW54_RS05350 c8a9d129c700a5de0b6d27835bacbdcf 1208 Pfam PF04561 RNA polymerase Rpb2, domain 2 383 417 8.3E-7 T 28-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDW54_RS05350 c8a9d129c700a5de0b6d27835bacbdcf 1208 Gene3D G3DSA:2.40.270.10 848 1054 4.8E-76 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDW54_RS05350 c8a9d129c700a5de0b6d27835bacbdcf 1208 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 223 895 0.0 T 28-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDW54_RS08220 73408dedb308ca60a90d69c086642274 114 Gene3D G3DSA:3.30.1820.10 2 111 6.6E-44 T 28-03-2018 IPR014965 Putative amino acid metabolism CDW54_RS08220 73408dedb308ca60a90d69c086642274 114 Pfam PF08866 Putative amino acid metabolism 1 111 1.1E-43 T 28-03-2018 IPR014965 Putative amino acid metabolism CDW54_RS08220 73408dedb308ca60a90d69c086642274 114 SUPERFAMILY SSF160800 1 112 7.98E-42 T 28-03-2018 IPR014965 Putative amino acid metabolism CDW54_RS01090 0c754400d260e2b60340bf688b9a1514 888 Pfam PF00702 haloacid dehalogenase-like hydrolase 338 641 1.1E-23 T 28-03-2018 CDW54_RS01090 0c754400d260e2b60340bf688b9a1514 888 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 594 715 2.4E-34 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDW54_RS01090 0c754400d260e2b60340bf688b9a1514 888 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 89 361 1.1E-39 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDW54_RS01090 0c754400d260e2b60340bf688b9a1514 888 SUPERFAMILY SSF81665 12 121 8.24E-112 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CDW54_RS01090 0c754400d260e2b60340bf688b9a1514 888 SUPERFAMILY SSF81665 231 334 8.24E-112 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CDW54_RS01090 0c754400d260e2b60340bf688b9a1514 888 SUPERFAMILY SSF81665 676 885 8.24E-112 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CDW54_RS01090 0c754400d260e2b60340bf688b9a1514 888 SUPERFAMILY SSF56784 483 731 1.9E-61 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS01090 0c754400d260e2b60340bf688b9a1514 888 SUPERFAMILY SSF56784 338 358 1.9E-61 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS01090 0c754400d260e2b60340bf688b9a1514 888 Pfam PF00689 Cation transporting ATPase, C-terminus 711 880 1.6E-37 T 28-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 CDW54_RS01090 0c754400d260e2b60340bf688b9a1514 888 Pfam PF00690 Cation transporter/ATPase, N-terminus 13 77 1.3E-16 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CDW54_RS01090 0c754400d260e2b60340bf688b9a1514 888 SUPERFAMILY SSF81660 346 537 3.92E-53 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CDW54_RS01090 0c754400d260e2b60340bf688b9a1514 888 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 658 683 1.3E-16 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDW54_RS01090 0c754400d260e2b60340bf688b9a1514 888 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 599 615 1.3E-16 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDW54_RS01090 0c754400d260e2b60340bf688b9a1514 888 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 627 643 1.3E-16 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDW54_RS01090 0c754400d260e2b60340bf688b9a1514 888 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 486 504 1.3E-16 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDW54_RS01090 0c754400d260e2b60340bf688b9a1514 888 Gene3D G3DSA:2.70.150.10 18 231 9.4E-49 T 28-03-2018 CDW54_RS01090 0c754400d260e2b60340bf688b9a1514 888 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 650 662 4.3E-40 T 28-03-2018 CDW54_RS01090 0c754400d260e2b60340bf688b9a1514 888 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 168 182 4.3E-40 T 28-03-2018 CDW54_RS01090 0c754400d260e2b60340bf688b9a1514 888 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 627 646 4.3E-40 T 28-03-2018 CDW54_RS01090 0c754400d260e2b60340bf688b9a1514 888 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 525 536 4.3E-40 T 28-03-2018 CDW54_RS01090 0c754400d260e2b60340bf688b9a1514 888 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 547 557 4.3E-40 T 28-03-2018 CDW54_RS01090 0c754400d260e2b60340bf688b9a1514 888 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 340 354 4.3E-40 T 28-03-2018 CDW54_RS01090 0c754400d260e2b60340bf688b9a1514 888 Gene3D G3DSA:1.20.1110.10 525 884 8.1E-86 T 28-03-2018 CDW54_RS01090 0c754400d260e2b60340bf688b9a1514 888 SUPERFAMILY SSF81653 122 229 1.23E-31 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CDW54_RS01090 0c754400d260e2b60340bf688b9a1514 888 Gene3D G3DSA:3.40.1110.10 302 524 3.0E-51 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CDW54_RS01090 0c754400d260e2b60340bf688b9a1514 888 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 342 348 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CDW54_RS01090 0c754400d260e2b60340bf688b9a1514 888 SMART SM00831 10 83 1.9E-19 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CDW54_RS01090 0c754400d260e2b60340bf688b9a1514 888 Pfam PF00122 E1-E2 ATPase 118 320 3.3E-54 T 28-03-2018 CDW54_RS10305 268b045c3f6adcecf9e6d7f59c0c7d45 230 SUPERFAMILY SSF55846 2 72 3.6E-8 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CDW54_RS10305 268b045c3f6adcecf9e6d7f59c0c7d45 230 Gene3D G3DSA:3.40.80.10 1 100 2.3E-6 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CDW54_RS10125 9dcc4e72d7409a1d9717a0486a226564 316 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 60 249 4.5E-48 T 28-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal CDW54_RS10125 9dcc4e72d7409a1d9717a0486a226564 316 Hamap MF_01811 Membrane protein insertase YidC [yidC]. 4 253 28.258 T 28-03-2018 IPR023060 Membrane insertase YidC/YidC1/YidC2, Firmicutes CDW54_RS10125 9dcc4e72d7409a1d9717a0486a226564 316 Pfam PF02096 60Kd inner membrane protein 61 249 3.5E-44 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CDW54_RS10125 9dcc4e72d7409a1d9717a0486a226564 316 PRINTS PR00701 60kDa inner membrane protein signature 216 239 8.8E-9 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CDW54_RS10125 9dcc4e72d7409a1d9717a0486a226564 316 PRINTS PR00701 60kDa inner membrane protein signature 133 156 8.8E-9 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CDW54_RS11245 e37e509cc63de49b4c4c1a1ee75d1735 344 Gene3D G3DSA:1.10.260.40 16 48 1.1E-12 T 28-03-2018 CDW54_RS11245 e37e509cc63de49b4c4c1a1ee75d1735 344 SUPERFAMILY SSF53822 73 317 1.91E-39 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CDW54_RS11245 e37e509cc63de49b4c4c1a1ee75d1735 344 Gene3D G3DSA:3.40.50.2300 174 317 2.5E-33 T 28-03-2018 CDW54_RS11245 e37e509cc63de49b4c4c1a1ee75d1735 344 Gene3D G3DSA:3.40.50.2300 55 173 2.1E-12 T 28-03-2018 CDW54_RS11245 e37e509cc63de49b4c4c1a1ee75d1735 344 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 28-03-2018 CDW54_RS11245 e37e509cc63de49b4c4c1a1ee75d1735 344 SUPERFAMILY SSF47413 3 49 3.09E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDW54_RS11245 e37e509cc63de49b4c4c1a1ee75d1735 344 Gene3D G3DSA:1.10.10.60 2 15 0.11 T 28-03-2018 CDW54_RS11245 e37e509cc63de49b4c4c1a1ee75d1735 344 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 7.4E-15 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS11245 e37e509cc63de49b4c4c1a1ee75d1735 344 SMART SM00354 1 71 2.0E-11 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS11245 e37e509cc63de49b4c4c1a1ee75d1735 344 Pfam PF13377 Periplasmic binding protein-like domain 169 336 4.9E-31 T 28-03-2018 CDW54_RS11245 e37e509cc63de49b4c4c1a1ee75d1735 344 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 9.9E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS11245 e37e509cc63de49b4c4c1a1ee75d1735 344 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 9.9E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS00765 b1def13bbd6b6c7efaa1442dd39a45bb 692 SUPERFAMILY SSF57783 574 614 2.04E-13 T 28-03-2018 CDW54_RS00765 b1def13bbd6b6c7efaa1442dd39a45bb 692 SMART SM00436 105 193 8.1E-49 T 28-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 CDW54_RS00765 b1def13bbd6b6c7efaa1442dd39a45bb 692 Gene3D G3DSA:3.30.65.10 559 615 2.8E-17 T 28-03-2018 CDW54_RS00765 b1def13bbd6b6c7efaa1442dd39a45bb 692 Gene3D G3DSA:3.30.65.10 616 654 1.7E-9 T 28-03-2018 CDW54_RS00765 b1def13bbd6b6c7efaa1442dd39a45bb 692 Gene3D G3DSA:3.30.65.10 655 685 0.0043 T 28-03-2018 CDW54_RS00765 b1def13bbd6b6c7efaa1442dd39a45bb 692 SMART SM00493 4 104 3.2E-29 T 28-03-2018 IPR006171 TOPRIM domain CDW54_RS00765 b1def13bbd6b6c7efaa1442dd39a45bb 692 Pfam PF01131 DNA topoisomerase 129 549 1.9E-131 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CDW54_RS00765 b1def13bbd6b6c7efaa1442dd39a45bb 692 Pfam PF01751 Toprim domain 6 114 4.3E-30 T 28-03-2018 IPR006171 TOPRIM domain CDW54_RS00765 b1def13bbd6b6c7efaa1442dd39a45bb 692 Gene3D G3DSA:3.40.50.140 3 130 2.7E-40 T 28-03-2018 CDW54_RS00765 b1def13bbd6b6c7efaa1442dd39a45bb 692 Gene3D G3DSA:1.10.460.10 136 328 9.4E-47 T 28-03-2018 CDW54_RS00765 b1def13bbd6b6c7efaa1442dd39a45bb 692 Gene3D G3DSA:2.70.20.10 329 457 1.3E-41 T 28-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CDW54_RS00765 b1def13bbd6b6c7efaa1442dd39a45bb 692 SUPERFAMILY SSF56712 4 590 1.02E-195 T 28-03-2018 IPR023405 DNA topoisomerase, type IA, core domain CDW54_RS00765 b1def13bbd6b6c7efaa1442dd39a45bb 692 SMART SM00437 243 511 1.1E-117 T 28-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 CDW54_RS00765 b1def13bbd6b6c7efaa1442dd39a45bb 692 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 280 303 - T 28-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 CDW54_RS00765 b1def13bbd6b6c7efaa1442dd39a45bb 692 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 579 614 3.0E-14 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CDW54_RS00765 b1def13bbd6b6c7efaa1442dd39a45bb 692 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 659 683 0.12 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CDW54_RS00765 b1def13bbd6b6c7efaa1442dd39a45bb 692 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 618 656 9.9E-13 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CDW54_RS00765 b1def13bbd6b6c7efaa1442dd39a45bb 692 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 6 612 2.2E-254 T 28-03-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 CDW54_RS00765 b1def13bbd6b6c7efaa1442dd39a45bb 692 Hamap MF_00952 DNA topoisomerase 1 [topA]. 4 634 56.82 T 28-03-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 CDW54_RS00765 b1def13bbd6b6c7efaa1442dd39a45bb 692 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 371 387 1.4E-36 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CDW54_RS00765 b1def13bbd6b6c7efaa1442dd39a45bb 692 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 474 488 1.4E-36 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CDW54_RS00765 b1def13bbd6b6c7efaa1442dd39a45bb 692 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 78 91 1.4E-36 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CDW54_RS00765 b1def13bbd6b6c7efaa1442dd39a45bb 692 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 163 181 1.4E-36 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CDW54_RS00765 b1def13bbd6b6c7efaa1442dd39a45bb 692 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 294 303 1.4E-36 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CDW54_RS09185 024a17c6ab8c3749e9fe7b5e32cdbf3f 357 Gene3D G3DSA:3.40.190.10 152 307 6.0E-38 T 28-03-2018 CDW54_RS09185 024a17c6ab8c3749e9fe7b5e32cdbf3f 357 SUPERFAMILY SSF53850 35 353 2.07E-94 T 28-03-2018 CDW54_RS09185 024a17c6ab8c3749e9fe7b5e32cdbf3f 357 Pfam PF13416 Bacterial extracellular solute-binding protein 50 321 1.1E-36 T 28-03-2018 CDW54_RS09185 024a17c6ab8c3749e9fe7b5e32cdbf3f 357 PIRSF PIRSF019574 1 356 2.0E-134 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CDW54_RS09185 024a17c6ab8c3749e9fe7b5e32cdbf3f 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 56 77 7.6E-58 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CDW54_RS09185 024a17c6ab8c3749e9fe7b5e32cdbf3f 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 83 97 7.6E-58 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CDW54_RS09185 024a17c6ab8c3749e9fe7b5e32cdbf3f 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 211 230 7.6E-58 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CDW54_RS09185 024a17c6ab8c3749e9fe7b5e32cdbf3f 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 40 56 7.6E-58 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CDW54_RS09185 024a17c6ab8c3749e9fe7b5e32cdbf3f 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 300 326 7.6E-58 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CDW54_RS09185 024a17c6ab8c3749e9fe7b5e32cdbf3f 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 255 274 7.6E-58 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CDW54_RS09185 024a17c6ab8c3749e9fe7b5e32cdbf3f 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 156 170 7.6E-58 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CDW54_RS09185 024a17c6ab8c3749e9fe7b5e32cdbf3f 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 130 146 7.6E-58 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CDW54_RS09185 024a17c6ab8c3749e9fe7b5e32cdbf3f 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 174 193 7.6E-58 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CDW54_RS09185 024a17c6ab8c3749e9fe7b5e32cdbf3f 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 99 112 7.6E-58 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CDW54_RS09185 024a17c6ab8c3749e9fe7b5e32cdbf3f 357 Gene3D G3DSA:3.40.190.10 24 151 2.4E-30 T 28-03-2018 CDW54_RS11060 5d9dbeb50fbd68fef6e89d3c800da45d 173 SUPERFAMILY SSF52833 2 171 7.41E-30 T 28-03-2018 IPR012336 Thioredoxin-like fold CDW54_RS11060 5d9dbeb50fbd68fef6e89d3c800da45d 173 Gene3D G3DSA:1.10.1200.90 69 121 3.5E-26 T 28-03-2018 CDW54_RS11060 5d9dbeb50fbd68fef6e89d3c800da45d 173 Gene3D G3DSA:3.40.30.10 122 173 0.0065 T 28-03-2018 CDW54_RS11060 5d9dbeb50fbd68fef6e89d3c800da45d 173 Pfam PF13462 Thioredoxin 13 171 1.6E-40 T 28-03-2018 IPR012336 Thioredoxin-like fold CDW54_RS06790 3e3aff31770206c5b49d8da5643668f4 228 Gene3D G3DSA:1.20.120.530 65 209 1.1E-17 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CDW54_RS06790 3e3aff31770206c5b49d8da5643668f4 228 SUPERFAMILY SSF48008 82 205 1.57E-16 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CDW54_RS06790 3e3aff31770206c5b49d8da5643668f4 228 SUPERFAMILY SSF46785 5 78 2.38E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS06790 3e3aff31770206c5b49d8da5643668f4 228 SMART SM00345 10 68 4.3E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDW54_RS06790 3e3aff31770206c5b49d8da5643668f4 228 SMART SM00895 78 203 2.3E-4 T 28-03-2018 IPR011711 GntR, C-terminal CDW54_RS06790 3e3aff31770206c5b49d8da5643668f4 228 Gene3D G3DSA:1.10.10.10 4 64 5.1E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS06790 3e3aff31770206c5b49d8da5643668f4 228 Pfam PF07729 FCD domain 83 202 7.3E-21 T 28-03-2018 IPR011711 GntR, C-terminal CDW54_RS06790 3e3aff31770206c5b49d8da5643668f4 228 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 68 6.4E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDW54_RS01195 2dbd46e45f560f08702ce8dee87f6af7 99 SUPERFAMILY SSF52794 1 93 2.09E-17 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CDW54_RS01195 2dbd46e45f560f08702ce8dee87f6af7 99 Gene3D G3DSA:3.40.50.2300 1 93 1.1E-16 T 28-03-2018 CDW54_RS01195 2dbd46e45f560f08702ce8dee87f6af7 99 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 2 89 9.7E-15 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CDW54_RS12265 3224b6471f32a98127b4e6a76687148e 132 Pfam PF02661 Fic/DOC family 3 87 3.1E-14 T 28-03-2018 IPR003812 Fido domain CDW54_RS12265 3224b6471f32a98127b4e6a76687148e 132 Gene3D G3DSA:1.10.3290.10 6 128 4.3E-10 T 28-03-2018 IPR003812 Fido domain CDW54_RS12265 3224b6471f32a98127b4e6a76687148e 132 TIGRFAM TIGR01550 DOC_P1: death-on-curing family protein 4 122 3.3E-22 T 28-03-2018 IPR006440 Death on curing protein GO:0016301 CDW54_RS12265 3224b6471f32a98127b4e6a76687148e 132 SUPERFAMILY SSF140931 47 99 3.27E-8 T 28-03-2018 IPR003812 Fido domain CDW54_RS00735 3c38c33bfd4d543e4e6ff4b661728c84 291 Pfam PF01263 Aldose 1-epimerase 3 266 8.3E-36 T 28-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 CDW54_RS00735 3c38c33bfd4d543e4e6ff4b661728c84 291 Gene3D G3DSA:2.70.98.10 1 291 1.5E-64 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CDW54_RS00735 3c38c33bfd4d543e4e6ff4b661728c84 291 SUPERFAMILY SSF74650 3 290 5.65E-58 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CDW54_RS02020 1ef132f896456c4d1b8a7e26c6db5b44 235 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 36 1.4E-18 T 28-03-2018 IPR019933 DivIVA domain CDW54_RS02020 1ef132f896456c4d1b8a7e26c6db5b44 235 Pfam PF05103 DivIVA protein 3 116 1.9E-40 T 28-03-2018 IPR007793 DivIVA family CDW54_RS02020 1ef132f896456c4d1b8a7e26c6db5b44 235 Pfam PF05103 DivIVA protein 95 154 9.1E-11 T 28-03-2018 IPR007793 DivIVA family CDW54_RS02020 1ef132f896456c4d1b8a7e26c6db5b44 235 Gene3D G3DSA:1.20.120.20 21 198 5.5E-5 T 28-03-2018 CDW54_RS01005 11a4c9904f3b99de00636ee0b14445e9 699 Gene3D G3DSA:2.20.25.10 1 34 6.4E-5 T 28-03-2018 CDW54_RS07785 df15f51d713070f9225bc40af91ed8d0 507 PRINTS PR00691 Adhesin B signature 76 95 1.6E-15 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CDW54_RS07785 df15f51d713070f9225bc40af91ed8d0 507 PRINTS PR00691 Adhesin B signature 32 53 1.6E-15 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CDW54_RS07785 df15f51d713070f9225bc40af91ed8d0 507 PRINTS PR00691 Adhesin B signature 198 215 1.6E-15 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CDW54_RS07785 df15f51d713070f9225bc40af91ed8d0 507 PRINTS PR00691 Adhesin B signature 57 75 1.6E-15 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CDW54_RS07785 df15f51d713070f9225bc40af91ed8d0 507 PRINTS PR00691 Adhesin B signature 291 309 1.6E-15 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CDW54_RS07785 df15f51d713070f9225bc40af91ed8d0 507 Gene3D G3DSA:2.40.128.20 319 507 1.8E-65 T 28-03-2018 IPR012674 Calycin CDW54_RS07785 df15f51d713070f9225bc40af91ed8d0 507 Pfam PF01297 Zinc-uptake complex component A periplasmic 35 310 7.4E-79 T 28-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 CDW54_RS07785 df15f51d713070f9225bc40af91ed8d0 507 Pfam PF09223 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment 327 507 1.6E-81 T 28-03-2018 IPR015304 ZinT domain GO:0008270 CDW54_RS07785 df15f51d713070f9225bc40af91ed8d0 507 PRINTS PR00690 Adhesin family signature 76 93 1.3E-12 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CDW54_RS07785 df15f51d713070f9225bc40af91ed8d0 507 PRINTS PR00690 Adhesin family signature 32 50 1.3E-12 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CDW54_RS07785 df15f51d713070f9225bc40af91ed8d0 507 PRINTS PR00690 Adhesin family signature 198 219 1.3E-12 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CDW54_RS07785 df15f51d713070f9225bc40af91ed8d0 507 PRINTS PR00690 Adhesin family signature 63 76 1.3E-12 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CDW54_RS07785 df15f51d713070f9225bc40af91ed8d0 507 SUPERFAMILY SSF50814 326 507 1.44E-74 T 28-03-2018 IPR012674 Calycin CDW54_RS07785 df15f51d713070f9225bc40af91ed8d0 507 Gene3D G3DSA:3.40.50.1980 193 311 4.5E-36 T 28-03-2018 CDW54_RS07785 df15f51d713070f9225bc40af91ed8d0 507 Gene3D G3DSA:3.40.50.1980 32 192 9.0E-56 T 28-03-2018 CDW54_RS07785 df15f51d713070f9225bc40af91ed8d0 507 SUPERFAMILY SSF53807 31 310 1.96E-84 T 28-03-2018 CDW54_RS00855 f2be9c69d399d0f1f28f3757a4398ce6 628 SMART SM00382 347 519 5.6E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS00855 f2be9c69d399d0f1f28f3757a4398ce6 628 SMART SM00382 29 242 7.6E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS00855 f2be9c69d399d0f1f28f3757a4398ce6 628 Pfam PF12848 ABC transporter 229 298 2.1E-9 T 28-03-2018 IPR032781 ABC-transporter extension domain CDW54_RS00855 f2be9c69d399d0f1f28f3757a4398ce6 628 Pfam PF16326 ABC transporter C-terminal domain 558 624 5.2E-18 T 28-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 CDW54_RS00855 f2be9c69d399d0f1f28f3757a4398ce6 628 ProSitePatterns PS00211 ABC transporters family signature. 445 459 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS00855 f2be9c69d399d0f1f28f3757a4398ce6 628 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS00855 f2be9c69d399d0f1f28f3757a4398ce6 628 SUPERFAMILY SSF52540 10 244 5.1E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS00855 f2be9c69d399d0f1f28f3757a4398ce6 628 Gene3D G3DSA:3.40.50.300 2 271 4.7E-52 T 28-03-2018 CDW54_RS00855 f2be9c69d399d0f1f28f3757a4398ce6 628 Gene3D G3DSA:3.40.50.300 285 558 1.6E-51 T 28-03-2018 CDW54_RS00855 f2be9c69d399d0f1f28f3757a4398ce6 628 SUPERFAMILY SSF52540 314 529 8.54E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS00855 f2be9c69d399d0f1f28f3757a4398ce6 628 Pfam PF00005 ABC transporter 339 473 2.2E-20 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS00855 f2be9c69d399d0f1f28f3757a4398ce6 628 Pfam PF00005 ABC transporter 21 190 2.4E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS06610 65d4cbcba866b05e4426c71eb3c46610 901 Pfam PF01061 ABC-2 type transporter 735 848 9.1E-8 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CDW54_RS06610 65d4cbcba866b05e4426c71eb3c46610 901 Gene3D G3DSA:1.20.1480.30 340 430 0.0022 T 28-03-2018 CDW54_RS06610 65d4cbcba866b05e4426c71eb3c46610 901 Gene3D G3DSA:1.20.58.60 222 339 0.036 T 28-03-2018 CDW54_RS06610 65d4cbcba866b05e4426c71eb3c46610 901 Gene3D G3DSA:1.20.120.20 431 655 2.3E-11 T 28-03-2018 CDW54_RS06610 65d4cbcba866b05e4426c71eb3c46610 901 Gene3D G3DSA:3.40.1710.10 51 221 5.4E-26 T 28-03-2018 CDW54_RS06610 65d4cbcba866b05e4426c71eb3c46610 901 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 677 880 3.3E-45 T 28-03-2018 IPR017501 Phage infection protein, YhgE, C-terminal CDW54_RS06610 65d4cbcba866b05e4426c71eb3c46610 901 Pfam PF12698 ABC-2 family transporter protein 26 173 2.4E-11 T 28-03-2018 CDW54_RS06610 65d4cbcba866b05e4426c71eb3c46610 901 SUPERFAMILY SSF58104 246 428 4.45E-5 T 28-03-2018 CDW54_RS06610 65d4cbcba866b05e4426c71eb3c46610 901 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 14 176 2.2E-46 T 28-03-2018 IPR017500 Phage infection protein, YhgE, N-terminal CDW54_RS12515 bd7442670109c076a292ef8030e4c215 388 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 201 212 - T 28-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CDW54_RS12515 bd7442670109c076a292ef8030e4c215 388 Pfam PF02926 THUMP domain 29 157 2.6E-8 T 28-03-2018 IPR004114 THUMP domain GO:0003723 CDW54_RS12515 bd7442670109c076a292ef8030e4c215 388 SUPERFAMILY SSF53335 260 374 2.69E-38 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDW54_RS12515 bd7442670109c076a292ef8030e4c215 388 SUPERFAMILY SSF53335 149 223 2.69E-38 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDW54_RS12515 bd7442670109c076a292ef8030e4c215 388 Gene3D G3DSA:3.40.50.150 166 387 8.3E-34 T 28-03-2018 CDW54_RS12515 bd7442670109c076a292ef8030e4c215 388 Pfam PF01170 Putative RNA methylase family UPF0020 168 370 1.3E-58 T 28-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CDW54_RS12515 bd7442670109c076a292ef8030e4c215 388 SMART SM00981 60 160 2.0E-8 T 28-03-2018 IPR004114 THUMP domain GO:0003723 CDW54_RS12515 bd7442670109c076a292ef8030e4c215 388 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 305 311 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CDW54_RS04475 03423aec4b0b3c4d2b34a144871e2b4c 501 Pfam PF08245 Mur ligase middle domain 119 325 4.7E-34 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CDW54_RS04475 03423aec4b0b3c4d2b34a144871e2b4c 501 Pfam PF02875 Mur ligase family, glutamate ligase domain 344 430 2.1E-17 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CDW54_RS04475 03423aec4b0b3c4d2b34a144871e2b4c 501 Gene3D G3DSA:3.40.1390.10 11 108 8.1E-13 T 28-03-2018 CDW54_RS04475 03423aec4b0b3c4d2b34a144871e2b4c 501 SUPERFAMILY SSF53623 109 340 1.03E-44 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CDW54_RS04475 03423aec4b0b3c4d2b34a144871e2b4c 501 Gene3D G3DSA:3.90.190.20 351 501 4.5E-34 T 28-03-2018 CDW54_RS04475 03423aec4b0b3c4d2b34a144871e2b4c 501 SUPERFAMILY SSF63418 18 109 7.32E-14 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CDW54_RS04475 03423aec4b0b3c4d2b34a144871e2b4c 501 Gene3D G3DSA:3.40.1190.10 109 348 4.1E-43 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CDW54_RS04475 03423aec4b0b3c4d2b34a144871e2b4c 501 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 37 497 2.0E-93 T 28-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 CDW54_RS04475 03423aec4b0b3c4d2b34a144871e2b4c 501 SUPERFAMILY SSF53244 344 499 2.29E-35 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CDW54_RS04475 03423aec4b0b3c4d2b34a144871e2b4c 501 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 6 499 27.519 T 28-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 CDW54_RS08395 74812bf654c4810633af142a67e381d4 463 Gene3D G3DSA:3.40.50.300 137 363 5.6E-14 T 28-03-2018 CDW54_RS08395 74812bf654c4810633af142a67e381d4 463 SUPERFAMILY SSF52540 198 343 2.12E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS08395 74812bf654c4810633af142a67e381d4 463 TIGRFAM TIGR01613 primase_Cterm: phage/plasmid primase, P4 family, C-terminal domain 125 429 2.2E-58 T 28-03-2018 IPR006500 DNA primase, phage/plasmid CDW54_RS08395 74812bf654c4810633af142a67e381d4 463 Pfam PF08706 D5 N terminal like 119 174 1.8E-8 T 28-03-2018 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal CDW54_RS08395 74812bf654c4810633af142a67e381d4 463 Pfam PF03288 Poxvirus D5 protein-like 381 438 1.4E-4 T 28-03-2018 IPR004968 DNA primase/nucleoside triphosphatase, C-terminal CDW54_RS09875 e3f4f5fdb62f367630033ab1492b1286 333 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 52 2.8E-19 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS09875 e3f4f5fdb62f367630033ab1492b1286 333 Gene3D G3DSA:3.40.50.2300 179 315 3.0E-32 T 28-03-2018 CDW54_RS09875 e3f4f5fdb62f367630033ab1492b1286 333 ProSitePatterns PS00356 LacI-type HTH domain signature. 8 26 - T 28-03-2018 CDW54_RS09875 e3f4f5fdb62f367630033ab1492b1286 333 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 7 17 4.4E-6 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS09875 e3f4f5fdb62f367630033ab1492b1286 333 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 17 27 4.4E-6 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS09875 e3f4f5fdb62f367630033ab1492b1286 333 Pfam PF13377 Periplasmic binding protein-like domain 172 332 3.5E-25 T 28-03-2018 CDW54_RS09875 e3f4f5fdb62f367630033ab1492b1286 333 TIGRFAM TIGR01481 ccpA: catabolite control protein A 4 333 8.8E-165 T 28-03-2018 IPR006377 Catabolite control protein A GO:0006355 CDW54_RS09875 e3f4f5fdb62f367630033ab1492b1286 333 SUPERFAMILY SSF47413 5 63 1.91E-19 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDW54_RS09875 e3f4f5fdb62f367630033ab1492b1286 333 Gene3D G3DSA:1.10.260.40 6 58 6.4E-25 T 28-03-2018 CDW54_RS09875 e3f4f5fdb62f367630033ab1492b1286 333 SUPERFAMILY SSF53822 65 333 1.73E-71 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CDW54_RS09875 e3f4f5fdb62f367630033ab1492b1286 333 Gene3D G3DSA:3.40.50.2300 59 178 3.6E-32 T 28-03-2018 CDW54_RS09875 e3f4f5fdb62f367630033ab1492b1286 333 SMART SM00354 5 75 3.1E-36 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS10420 06a46784c6b5f5f60b83b7fc6e4329ba 115 PIRSF PIRSF002191 1 115 2.0E-50 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS10420 06a46784c6b5f5f60b83b7fc6e4329ba 115 Pfam PF01245 Ribosomal protein L19 4 112 2.3E-52 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS10420 06a46784c6b5f5f60b83b7fc6e4329ba 115 ProSitePatterns PS01015 Ribosomal protein L19 signature. 86 101 - T 28-03-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS10420 06a46784c6b5f5f60b83b7fc6e4329ba 115 PRINTS PR00061 Ribosomal protein L19 signature 4 33 1.1E-42 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS10420 06a46784c6b5f5f60b83b7fc6e4329ba 115 PRINTS PR00061 Ribosomal protein L19 signature 34 63 1.1E-42 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS10420 06a46784c6b5f5f60b83b7fc6e4329ba 115 PRINTS PR00061 Ribosomal protein L19 signature 88 113 1.1E-42 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS10420 06a46784c6b5f5f60b83b7fc6e4329ba 115 SUPERFAMILY SSF50104 1 114 7.92E-48 T 28-03-2018 IPR008991 Translation protein SH3-like domain CDW54_RS10420 06a46784c6b5f5f60b83b7fc6e4329ba 115 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 4 113 8.7E-51 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS10420 06a46784c6b5f5f60b83b7fc6e4329ba 115 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 2 114 32.078 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS05120 55ed3931317fe042dab69b883dabba1f 415 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 321 342 - T 28-03-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CDW54_RS05120 55ed3931317fe042dab69b883dabba1f 415 PIRSF PIRSF000151 1 415 6.9E-178 T 28-03-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 CDW54_RS05120 55ed3931317fe042dab69b883dabba1f 415 SUPERFAMILY SSF53720 3 414 1.83E-117 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CDW54_RS05120 55ed3931317fe042dab69b883dabba1f 415 Pfam PF00171 Aldehyde dehydrogenase family 9 278 9.1E-16 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CDW54_RS05120 55ed3931317fe042dab69b883dabba1f 415 Pfam PF00171 Aldehyde dehydrogenase family 315 404 5.9E-6 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CDW54_RS05120 55ed3931317fe042dab69b883dabba1f 415 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 11 404 4.0E-151 T 28-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CDW54_RS05120 55ed3931317fe042dab69b883dabba1f 415 Gene3D G3DSA:3.40.605.10 1 238 1.2E-41 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CDW54_RS05120 55ed3931317fe042dab69b883dabba1f 415 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 3 414 41.673 T 28-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CDW54_RS05120 55ed3931317fe042dab69b883dabba1f 415 Gene3D G3DSA:3.40.605.10 239 415 8.5E-42 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CDW54_RS09675 a5a4584f7fd24590e767573a6cc69502 433 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 418 42.765 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDW54_RS09675 a5a4584f7fd24590e767573a6cc69502 433 SUPERFAMILY SSF55205 1 419 1.44E-135 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CDW54_RS09675 a5a4584f7fd24590e767573a6cc69502 433 Gene3D G3DSA:3.65.10.10 220 421 3.6E-42 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CDW54_RS09675 a5a4584f7fd24590e767573a6cc69502 433 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 408 1.7E-106 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CDW54_RS09675 a5a4584f7fd24590e767573a6cc69502 433 Gene3D G3DSA:3.65.10.10 21 219 2.8E-46 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CDW54_RS09675 a5a4584f7fd24590e767573a6cc69502 433 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 417 6.0E-167 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDW54_RS11570 c77c42e57aa449f774ce3c990744819d 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 54 69 1.1E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CDW54_RS11570 c77c42e57aa449f774ce3c990744819d 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 18 33 1.1E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CDW54_RS11570 c77c42e57aa449f774ce3c990744819d 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 69 84 1.1E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CDW54_RS11570 c77c42e57aa449f774ce3c990744819d 117 Gene3D G3DSA:1.10.10.10 1 98 1.5E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS11570 c77c42e57aa449f774ce3c990744819d 117 SUPERFAMILY SSF46785 10 104 1.04E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS11570 c77c42e57aa449f774ce3c990744819d 117 SMART SM00418 16 103 3.8E-19 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CDW54_RS11570 c77c42e57aa449f774ce3c990744819d 117 Pfam PF01022 Bacterial regulatory protein, arsR family 26 72 5.2E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CDW54_RS00135 c09e15083869211cc36ea496177808c4 144 Pfam PF00582 Universal stress protein family 5 144 7.2E-33 T 28-03-2018 IPR006016 UspA GO:0006950 CDW54_RS00135 c09e15083869211cc36ea496177808c4 144 SUPERFAMILY SSF52402 5 144 2.26E-31 T 28-03-2018 CDW54_RS00135 c09e15083869211cc36ea496177808c4 144 PRINTS PR01438 Universal stress protein signature 5 23 4.7E-18 T 28-03-2018 IPR006015 Universal stress protein A CDW54_RS00135 c09e15083869211cc36ea496177808c4 144 PRINTS PR01438 Universal stress protein signature 122 144 4.7E-18 T 28-03-2018 IPR006015 Universal stress protein A CDW54_RS00135 c09e15083869211cc36ea496177808c4 144 PRINTS PR01438 Universal stress protein signature 104 116 4.7E-18 T 28-03-2018 IPR006015 Universal stress protein A CDW54_RS00135 c09e15083869211cc36ea496177808c4 144 Gene3D G3DSA:3.40.50.620 1 144 2.2E-33 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDW54_RS00135 c09e15083869211cc36ea496177808c4 144 PIRSF PIRSF006276 1 144 2.2E-20 T 28-03-2018 IPR006015 Universal stress protein A CDW54_RS02050 f379de19972bf322895308c4b13c422e 441 Gene3D G3DSA:3.30.1490.110 104 163 3.1E-25 T 28-03-2018 CDW54_RS02050 f379de19972bf322895308c4b13c422e 441 SUPERFAMILY SSF53067 197 364 2.01E-38 T 28-03-2018 CDW54_RS02050 f379de19972bf322895308c4b13c422e 441 SUPERFAMILY SSF53067 5 195 6.82E-59 T 28-03-2018 CDW54_RS02050 f379de19972bf322895308c4b13c422e 441 Gene3D G3DSA:3.30.420.40 195 247 3.1E-4 T 28-03-2018 CDW54_RS02050 f379de19972bf322895308c4b13c422e 441 Hamap MF_02033 Cell division protein FtsA [ftsA]. 3 440 28.67 T 28-03-2018 IPR020823 Cell division protein FtsA GO:0007049 CDW54_RS02050 f379de19972bf322895308c4b13c422e 441 PIRSF PIRSF003101 1 440 1.1E-140 T 28-03-2018 IPR020823 Cell division protein FtsA GO:0007049 CDW54_RS02050 f379de19972bf322895308c4b13c422e 441 Gene3D G3DSA:3.30.420.40 1 103 1.9E-8 T 28-03-2018 CDW54_RS02050 f379de19972bf322895308c4b13c422e 441 Gene3D G3DSA:3.90.640.10 248 298 4.9E-19 T 28-03-2018 CDW54_RS02050 f379de19972bf322895308c4b13c422e 441 SMART SM00842 7 194 4.7E-91 T 28-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 CDW54_RS02050 f379de19972bf322895308c4b13c422e 441 Pfam PF02491 SHS2 domain inserted in FTSA 84 157 3.3E-24 T 28-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 CDW54_RS02050 f379de19972bf322895308c4b13c422e 441 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 7 368 1.8E-102 T 28-03-2018 IPR020823 Cell division protein FtsA GO:0007049 CDW54_RS02050 f379de19972bf322895308c4b13c422e 441 Pfam PF14450 Cell division protein FtsA 205 365 2.8E-17 T 28-03-2018 CDW54_RS02050 f379de19972bf322895308c4b13c422e 441 Pfam PF14450 Cell division protein FtsA 8 180 8.6E-9 T 28-03-2018 CDW54_RS02050 f379de19972bf322895308c4b13c422e 441 Pfam PF11983 Membrane-attachment and polymerisation-promoting switch 377 441 2.4E-15 T 28-03-2018 IPR021873 Cell division protein FtsA, C-terminal CDW54_RS06605 5b5fe5e3ff6d1684994d687556a86369 315 SMART SM00829 10 311 2.0E-12 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CDW54_RS06605 5b5fe5e3ff6d1684994d687556a86369 315 Gene3D G3DSA:3.90.180.10 2 155 5.1E-44 T 28-03-2018 CDW54_RS06605 5b5fe5e3ff6d1684994d687556a86369 315 SUPERFAMILY SSF50129 1 143 1.05E-32 T 28-03-2018 IPR011032 GroES-like CDW54_RS06605 5b5fe5e3ff6d1684994d687556a86369 315 SUPERFAMILY SSF51735 115 241 1.13E-24 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS06605 5b5fe5e3ff6d1684994d687556a86369 315 Pfam PF13602 Zinc-binding dehydrogenase 185 311 4.1E-8 T 28-03-2018 CDW54_RS06605 5b5fe5e3ff6d1684994d687556a86369 315 Gene3D G3DSA:3.40.50.720 156 239 4.9E-9 T 28-03-2018 CDW54_RS06605 5b5fe5e3ff6d1684994d687556a86369 315 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 93 1.8E-9 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CDW54_RS01760 490b711f6ace78030a982b4327c74b65 243 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 128 240 7.4E-35 T 28-03-2018 IPR024425 Cell wall-active antibiotics response 4TMS YvqF CDW54_RS01760 490b711f6ace78030a982b4327c74b65 243 PIRSF PIRSF031509 1 243 2.9E-82 T 28-03-2018 IPR016975 Cell wall-active antibiotic response protein GO:0016021 CDW54_RS06805 b0d82368f04e9823eb16fc8eeab99b1a 472 Gene3D G3DSA:3.40.630.10 5 195 1.4E-28 T 28-03-2018 CDW54_RS06805 b0d82368f04e9823eb16fc8eeab99b1a 472 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 116 155 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CDW54_RS06805 b0d82368f04e9823eb16fc8eeab99b1a 472 TIGRFAM TIGR01886 dipeptidase: dipeptidase PepV 2 472 9.3E-228 T 28-03-2018 IPR011291 Peptidase M20A, peptidase V CDW54_RS06805 b0d82368f04e9823eb16fc8eeab99b1a 472 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 82 91 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CDW54_RS06805 b0d82368f04e9823eb16fc8eeab99b1a 472 SUPERFAMILY SSF55031 186 379 2.44E-49 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CDW54_RS06805 b0d82368f04e9823eb16fc8eeab99b1a 472 TIGRFAM TIGR01887 dipeptidaselike: putative dipeptidase 13 467 5.0E-175 T 28-03-2018 IPR010964 Peptidase M20A, peptidase V-related GO:0008270|GO:0016805 CDW54_RS06805 b0d82368f04e9823eb16fc8eeab99b1a 472 Gene3D G3DSA:3.30.70.360 286 376 1.6E-29 T 28-03-2018 CDW54_RS06805 b0d82368f04e9823eb16fc8eeab99b1a 472 Pfam PF01546 Peptidase family M20/M25/M40 86 468 6.3E-32 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CDW54_RS06805 b0d82368f04e9823eb16fc8eeab99b1a 472 Gene3D G3DSA:3.30.70.360 203 285 9.6E-11 T 28-03-2018 CDW54_RS06805 b0d82368f04e9823eb16fc8eeab99b1a 472 SUPERFAMILY SSF53187 1 186 3.55E-73 T 28-03-2018 CDW54_RS06805 b0d82368f04e9823eb16fc8eeab99b1a 472 SUPERFAMILY SSF53187 389 471 3.55E-73 T 28-03-2018 CDW54_RS00460 f2ac383f3f9b8ff582bf209e8e354b2b 430 SUPERFAMILY SSF55347 277 330 2.62E-29 T 28-03-2018 CDW54_RS00460 f2ac383f3f9b8ff582bf209e8e354b2b 430 SUPERFAMILY SSF55347 138 222 2.62E-29 T 28-03-2018 CDW54_RS00460 f2ac383f3f9b8ff582bf209e8e354b2b 430 SUPERFAMILY SSF51735 4 164 1.34E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS00460 f2ac383f3f9b8ff582bf209e8e354b2b 430 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 132 1.1E-15 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CDW54_RS00460 f2ac383f3f9b8ff582bf209e8e354b2b 430 Gene3D G3DSA:3.30.360.10 147 430 3.7E-45 T 28-03-2018 CDW54_RS00460 f2ac383f3f9b8ff582bf209e8e354b2b 430 Gene3D G3DSA:3.40.50.720 2 146 1.4E-24 T 28-03-2018 CDW54_RS00460 f2ac383f3f9b8ff582bf209e8e354b2b 430 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 144 224 1.4E-18 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CDW54_RS00595 d5e58ad2a1d7d72adc63de9aa4064b8a 230 SUPERFAMILY SSF57997 38 218 2.29E-7 T 28-03-2018 CDW54_RS00595 d5e58ad2a1d7d72adc63de9aa4064b8a 230 Gene3D G3DSA:1.20.5.1000 165 227 8.1E-5 T 28-03-2018 CDW54_RS00595 d5e58ad2a1d7d72adc63de9aa4064b8a 230 Gene3D G3DSA:1.20.5.50 92 164 5.6E-6 T 28-03-2018 CDW54_RS00595 d5e58ad2a1d7d72adc63de9aa4064b8a 230 Gene3D G3DSA:1.20.5.730 33 91 1.0E-7 T 28-03-2018 CDW54_RS09350 5c6227d141819e3da72e33d11845923b 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 6.0E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDW54_RS09350 5c6227d141819e3da72e33d11845923b 192 Gene3D G3DSA:1.10.10.60 48 139 2.3E-10 T 28-03-2018 CDW54_RS09350 5c6227d141819e3da72e33d11845923b 192 SUPERFAMILY SSF46689 4 79 9.23E-20 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDW54_RS09350 5c6227d141819e3da72e33d11845923b 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 5.9E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDW54_RS09350 5c6227d141819e3da72e33d11845923b 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 5.9E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDW54_RS09350 5c6227d141819e3da72e33d11845923b 192 ProSitePatterns PS01081 TetR-type HTH domain signature. 25 55 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CDW54_RS09350 5c6227d141819e3da72e33d11845923b 192 Gene3D G3DSA:1.10.10.60 3 47 3.7E-16 T 28-03-2018 CDW54_RS06835 260be910074a7f792eb06430b8ac149b 201 SUPERFAMILY SSF50249 91 199 4.16E-29 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDW54_RS06835 260be910074a7f792eb06430b8ac149b 201 Pfam PF14794 Domain of unknown function (DUF4479) 22 90 2.2E-27 T 28-03-2018 IPR027855 Domain of unknown function DUF4479 CDW54_RS06835 260be910074a7f792eb06430b8ac149b 201 Gene3D G3DSA:3.30.1940.10 23 89 4.2E-27 T 28-03-2018 IPR027855 Domain of unknown function DUF4479 CDW54_RS06835 260be910074a7f792eb06430b8ac149b 201 Pfam PF01588 Putative tRNA binding domain 95 197 2.9E-19 T 28-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CDW54_RS06835 260be910074a7f792eb06430b8ac149b 201 Gene3D G3DSA:2.40.50.140 90 201 9.9E-35 T 28-03-2018 CDW54_RS00620 6f4d6e43001a4a9ebf293c7616f923d4 247 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 69 234 7.6E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS00620 6f4d6e43001a4a9ebf293c7616f923d4 247 SUPERFAMILY SSF161098 48 230 6.8E-26 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS00620 6f4d6e43001a4a9ebf293c7616f923d4 247 Gene3D G3DSA:1.10.3720.10 43 243 8.8E-19 T 28-03-2018 CDW54_RS06075 df541f7c7c31dead0d443cd5af96ba98 248 PIRSF PIRSF001430 1 248 1.8E-79 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDW54_RS06075 df541f7c7c31dead0d443cd5af96ba98 248 Gene3D G3DSA:3.30.70.660 107 246 3.1E-39 T 28-03-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDW54_RS06075 df541f7c7c31dead0d443cd5af96ba98 248 Gene3D G3DSA:3.30.70.580 1 105 1.3E-33 T 28-03-2018 CDW54_RS06075 df541f7c7c31dead0d443cd5af96ba98 248 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 247 36.038 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDW54_RS06075 df541f7c7c31dead0d443cd5af96ba98 248 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 5 242 3.5E-63 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDW54_RS06075 df541f7c7c31dead0d443cd5af96ba98 248 SUPERFAMILY SSF55120 1 248 5.18E-82 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDW54_RS06075 df541f7c7c31dead0d443cd5af96ba98 248 Pfam PF01416 tRNA pseudouridine synthase 6 104 2.6E-14 T 28-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDW54_RS06075 df541f7c7c31dead0d443cd5af96ba98 248 Pfam PF01416 tRNA pseudouridine synthase 147 248 2.9E-29 T 28-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDW54_RS06800 014c2551e248027aa3c572e61f226d57 281 SUPERFAMILY SSF53613 2 270 8.29E-66 T 28-03-2018 IPR029056 Ribokinase-like CDW54_RS06800 014c2551e248027aa3c572e61f226d57 281 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 211 221 - T 28-03-2018 IPR017953 Carbohydrate kinase, predicted, conserved site CDW54_RS06800 014c2551e248027aa3c572e61f226d57 281 Pfam PF01256 Carbohydrate kinase 28 267 7.8E-60 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CDW54_RS06800 014c2551e248027aa3c572e61f226d57 281 Gene3D G3DSA:3.40.1190.20 1 281 3.2E-50 T 28-03-2018 IPR029056 Ribokinase-like CDW54_RS06800 014c2551e248027aa3c572e61f226d57 281 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 8 269 1.7E-57 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CDW54_RS06800 014c2551e248027aa3c572e61f226d57 281 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 4 274 23.343 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CDW54_RS12175 640b2de7dab77548e3f7ed213eac160c 446 Pfam PF00512 His Kinase A (phospho-acceptor) domain 221 286 6.3E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDW54_RS12175 640b2de7dab77548e3f7ed213eac160c 446 SMART SM00388 220 287 2.0E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDW54_RS12175 640b2de7dab77548e3f7ed213eac160c 446 Gene3D G3DSA:3.30.565.10 282 444 1.8E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS12175 640b2de7dab77548e3f7ed213eac160c 446 Gene3D G3DSA:1.10.287.130 215 281 9.1E-12 T 28-03-2018 CDW54_RS12175 640b2de7dab77548e3f7ed213eac160c 446 PRINTS PR00344 Bacterial sensor protein C-terminal signature 404 422 2.9E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDW54_RS12175 640b2de7dab77548e3f7ed213eac160c 446 PRINTS PR00344 Bacterial sensor protein C-terminal signature 428 441 2.9E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDW54_RS12175 640b2de7dab77548e3f7ed213eac160c 446 PRINTS PR00344 Bacterial sensor protein C-terminal signature 387 397 2.9E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDW54_RS12175 640b2de7dab77548e3f7ed213eac160c 446 PRINTS PR00344 Bacterial sensor protein C-terminal signature 369 383 2.9E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDW54_RS12175 640b2de7dab77548e3f7ed213eac160c 446 SUPERFAMILY SSF55874 276 442 3.8E-40 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS12175 640b2de7dab77548e3f7ed213eac160c 446 SUPERFAMILY SSF47384 217 287 9.22E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDW54_RS12175 640b2de7dab77548e3f7ed213eac160c 446 SMART SM00387 332 444 1.6E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS12175 640b2de7dab77548e3f7ed213eac160c 446 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 333 443 2.5E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS10930 43f0b3e95d9c0940763d5bce4e017893 122 SUPERFAMILY SSF159888 1 122 1.83E-32 T 28-03-2018 CDW54_RS10930 43f0b3e95d9c0940763d5bce4e017893 122 Pfam PF08818 Domain of unknown function (DU1801) 17 109 5.0E-9 T 28-03-2018 IPR014922 Domain of unknown function DUF1801 CDW54_RS04390 51dc3afd57a5927fd3400292f84dc0c1 285 Gene3D G3DSA:3.30.2350.10 80 282 6.9E-61 T 28-03-2018 CDW54_RS04390 51dc3afd57a5927fd3400292f84dc0c1 285 SUPERFAMILY SSF55120 80 276 2.56E-64 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDW54_RS04390 51dc3afd57a5927fd3400292f84dc0c1 285 Pfam PF00849 RNA pseudouridylate synthase 89 238 6.7E-31 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDW54_RS04390 51dc3afd57a5927fd3400292f84dc0c1 285 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 130 144 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDW54_RS04390 51dc3afd57a5927fd3400292f84dc0c1 285 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 38 275 1.3E-59 T 28-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDW54_RS04020 24846c3a4f8b031aded0bd316ab61b1f 207 SMART SM00563 35 145 2.9E-25 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CDW54_RS04020 24846c3a4f8b031aded0bd316ab61b1f 207 Gene3D G3DSA:3.40.1130.10 1 207 1.6E-37 T 28-03-2018 CDW54_RS04020 24846c3a4f8b031aded0bd316ab61b1f 207 Pfam PF01553 Acyltransferase 22 142 3.6E-19 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CDW54_RS04020 24846c3a4f8b031aded0bd316ab61b1f 207 SUPERFAMILY SSF69593 2 196 3.53E-48 T 28-03-2018 CDW54_RS02610 feb1bcd2d92f0b159d8468c1a030cb4f 322 SUPERFAMILY SSF53774 1 321 6.54E-97 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CDW54_RS02610 feb1bcd2d92f0b159d8468c1a030cb4f 322 Gene3D G3DSA:3.40.50.1170 1 205 3.6E-52 T 28-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 CDW54_RS02610 feb1bcd2d92f0b159d8468c1a030cb4f 322 PRINTS PR00139 Asparaginase/glutaminase family signature 4 15 1.8E-15 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CDW54_RS02610 feb1bcd2d92f0b159d8468c1a030cb4f 322 PRINTS PR00139 Asparaginase/glutaminase family signature 139 157 1.8E-15 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CDW54_RS02610 feb1bcd2d92f0b159d8468c1a030cb4f 322 PRINTS PR00139 Asparaginase/glutaminase family signature 79 97 1.8E-15 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CDW54_RS02610 feb1bcd2d92f0b159d8468c1a030cb4f 322 Gene3D G3DSA:3.40.50.40 206 322 1.4E-27 T 28-03-2018 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 CDW54_RS02610 feb1bcd2d92f0b159d8468c1a030cb4f 322 PIRSF PIRSF001220 1 322 2.6E-93 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CDW54_RS02610 feb1bcd2d92f0b159d8468c1a030cb4f 322 SMART SM00870 3 317 7.9E-133 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CDW54_RS02610 feb1bcd2d92f0b159d8468c1a030cb4f 322 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 6 14 - T 28-03-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 CDW54_RS02610 feb1bcd2d92f0b159d8468c1a030cb4f 322 PIRSF PIRSF500176 1 322 7.9E-89 T 28-03-2018 CDW54_RS02610 feb1bcd2d92f0b159d8468c1a030cb4f 322 Pfam PF00710 Asparaginase, N-terminal 3 190 2.9E-56 T 28-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 CDW54_RS02610 feb1bcd2d92f0b159d8468c1a030cb4f 322 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 80 90 - T 28-03-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 CDW54_RS02190 62cb797ae38a51d6b643ec4cb4ef17c5 944 Gene3D G3DSA:1.10.1790.10 812 938 2.4E-8 T 28-03-2018 IPR011608 PRD domain GO:0006355 CDW54_RS02190 62cb797ae38a51d6b643ec4cb4ef17c5 944 Gene3D G3DSA:1.10.1790.10 436 561 1.7E-18 T 28-03-2018 IPR011608 PRD domain GO:0006355 CDW54_RS02190 62cb797ae38a51d6b643ec4cb4ef17c5 944 Gene3D G3DSA:3.40.50.510 562 712 3.2E-28 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CDW54_RS02190 62cb797ae38a51d6b643ec4cb4ef17c5 944 Pfam PF03610 PTS system fructose IIA component 575 675 4.1E-14 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CDW54_RS02190 62cb797ae38a51d6b643ec4cb4ef17c5 944 Gene3D G3DSA:3.40.50.300 87 321 1.7E-23 T 28-03-2018 CDW54_RS02190 62cb797ae38a51d6b643ec4cb4ef17c5 944 SUPERFAMILY SSF52540 93 370 1.03E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS02190 62cb797ae38a51d6b643ec4cb4ef17c5 944 SUPERFAMILY SSF52794 712 793 1.05E-5 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CDW54_RS02190 62cb797ae38a51d6b643ec4cb4ef17c5 944 SUPERFAMILY SSF46785 20 67 7.74E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS02190 62cb797ae38a51d6b643ec4cb4ef17c5 944 Gene3D G3DSA:3.40.50.2300 713 808 3.5E-9 T 28-03-2018 CDW54_RS02190 62cb797ae38a51d6b643ec4cb4ef17c5 944 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 205 220 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CDW54_RS02190 62cb797ae38a51d6b643ec4cb4ef17c5 944 SMART SM00382 132 282 1.1E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS02190 62cb797ae38a51d6b643ec4cb4ef17c5 944 SUPERFAMILY SSF63520 464 568 1.19E-18 T 28-03-2018 IPR011608 PRD domain GO:0006355 CDW54_RS02190 62cb797ae38a51d6b643ec4cb4ef17c5 944 Pfam PF00158 Sigma-54 interaction domain 109 275 4.2E-48 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CDW54_RS02190 62cb797ae38a51d6b643ec4cb4ef17c5 944 Gene3D G3DSA:1.10.10.10 1 73 3.1E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS02190 62cb797ae38a51d6b643ec4cb4ef17c5 944 SUPERFAMILY SSF53062 573 692 5.62E-21 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CDW54_RS02190 62cb797ae38a51d6b643ec4cb4ef17c5 944 SUPERFAMILY SSF63520 827 938 8.5E-13 T 28-03-2018 IPR011608 PRD domain GO:0006355 CDW54_RS02190 62cb797ae38a51d6b643ec4cb4ef17c5 944 Pfam PF00874 PRD domain 478 564 5.5E-12 T 28-03-2018 IPR011608 PRD domain GO:0006355 CDW54_RS02190 62cb797ae38a51d6b643ec4cb4ef17c5 944 Pfam PF00874 PRD domain 853 933 3.2E-6 T 28-03-2018 IPR011608 PRD domain GO:0006355 CDW54_RS00810 7b202f2b9783fb9bb9dea993f971e7bd 183 Pfam PF00717 Peptidase S24-like 38 101 2.4E-20 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CDW54_RS00810 7b202f2b9783fb9bb9dea993f971e7bd 183 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 15 177 2.5E-49 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CDW54_RS00810 7b202f2b9783fb9bb9dea993f971e7bd 183 Gene3D G3DSA:2.10.109.10 27 183 3.4E-39 T 28-03-2018 CDW54_RS00810 7b202f2b9783fb9bb9dea993f971e7bd 183 ProSitePatterns PS00761 Signal peptidases I signature 3. 141 154 - T 28-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 CDW54_RS00810 7b202f2b9783fb9bb9dea993f971e7bd 183 SUPERFAMILY SSF51306 29 182 6.45E-49 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CDW54_RS00810 7b202f2b9783fb9bb9dea993f971e7bd 183 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 77 89 1.9E-17 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CDW54_RS00810 7b202f2b9783fb9bb9dea993f971e7bd 183 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 31 47 1.9E-17 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CDW54_RS00810 7b202f2b9783fb9bb9dea993f971e7bd 183 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 136 155 1.9E-17 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CDW54_RS00810 7b202f2b9783fb9bb9dea993f971e7bd 183 ProSitePatterns PS00760 Signal peptidases I lysine active site. 79 91 - T 28-03-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 CDW54_RS03855 f500f188a4c213b1b16a6be4feb064e7 366 SUPERFAMILY SSF51395 14 362 6.8E-90 T 28-03-2018 CDW54_RS03855 f500f188a4c213b1b16a6be4feb064e7 366 Pfam PF01070 FMN-dependent dehydrogenase 25 363 1.9E-112 T 28-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 CDW54_RS03855 f500f188a4c213b1b16a6be4feb064e7 366 PIRSF PIRSF000138 1 366 3.3E-128 T 28-03-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 CDW54_RS03855 f500f188a4c213b1b16a6be4feb064e7 366 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 262 268 - T 28-03-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 CDW54_RS03855 f500f188a4c213b1b16a6be4feb064e7 366 Gene3D G3DSA:3.20.20.70 13 365 4.3E-98 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDW54_RS10820 ee8fb532989a660445b9ba113814d75b 260 Gene3D G3DSA:3.40.50.10490 5 257 2.5E-99 T 28-03-2018 CDW54_RS10820 ee8fb532989a660445b9ba113814d75b 260 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 226 2.3E-107 T 28-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS10820 ee8fb532989a660445b9ba113814d75b 260 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 225 42.622 T 28-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS10820 ee8fb532989a660445b9ba113814d75b 260 PRINTS PR00395 Ribosomal protein S2 signature 6 24 6.8E-42 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS10820 ee8fb532989a660445b9ba113814d75b 260 PRINTS PR00395 Ribosomal protein S2 signature 158 175 6.8E-42 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS10820 ee8fb532989a660445b9ba113814d75b 260 PRINTS PR00395 Ribosomal protein S2 signature 37 46 6.8E-42 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS10820 ee8fb532989a660445b9ba113814d75b 260 PRINTS PR00395 Ribosomal protein S2 signature 196 210 6.8E-42 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS10820 ee8fb532989a660445b9ba113814d75b 260 PRINTS PR00395 Ribosomal protein S2 signature 175 186 6.8E-42 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS10820 ee8fb532989a660445b9ba113814d75b 260 PRINTS PR00395 Ribosomal protein S2 signature 87 104 6.8E-42 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS10820 ee8fb532989a660445b9ba113814d75b 260 SUPERFAMILY SSF52313 6 237 4.05E-97 T 28-03-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain CDW54_RS10820 ee8fb532989a660445b9ba113814d75b 260 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 28-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 CDW54_RS10820 ee8fb532989a660445b9ba113814d75b 260 Pfam PF00318 Ribosomal protein S2 9 224 1.5E-97 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS04785 6a49c3c3ef4e20bac373a6346d73c2ac 703 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 13 647 37.594 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 CDW54_RS04785 6a49c3c3ef4e20bac373a6346d73c2ac 703 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 133 626 1.6E-232 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 CDW54_RS04785 6a49c3c3ef4e20bac373a6346d73c2ac 703 Pfam PF01434 Peptidase family M41 419 625 1.1E-80 T 28-03-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 CDW54_RS04785 6a49c3c3ef4e20bac373a6346d73c2ac 703 Pfam PF06480 FtsH Extracellular 13 125 2.7E-10 T 28-03-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 CDW54_RS04785 6a49c3c3ef4e20bac373a6346d73c2ac 703 SMART SM00382 220 359 4.8E-24 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS04785 6a49c3c3ef4e20bac373a6346d73c2ac 703 SUPERFAMILY SSF140990 438 630 7.46E-69 T 28-03-2018 CDW54_RS04785 6a49c3c3ef4e20bac373a6346d73c2ac 703 ProSitePatterns PS00674 AAA-protein family signature. 327 345 - T 28-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CDW54_RS04785 6a49c3c3ef4e20bac373a6346d73c2ac 703 Gene3D G3DSA:3.40.50.300 165 370 1.4E-62 T 28-03-2018 CDW54_RS04785 6a49c3c3ef4e20bac373a6346d73c2ac 703 SUPERFAMILY SSF52540 181 427 6.4E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS04785 6a49c3c3ef4e20bac373a6346d73c2ac 703 Gene3D G3DSA:1.10.8.60 371 445 1.4E-23 T 28-03-2018 CDW54_RS04785 6a49c3c3ef4e20bac373a6346d73c2ac 703 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 224 356 3.3E-45 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CDW54_RS02855 3f2a97f573b852a195d888405a07137a 226 Pfam PF13610 DDE domain 72 203 7.4E-41 T 28-03-2018 IPR032874 DDE domain CDW54_RS02855 3f2a97f573b852a195d888405a07137a 226 SUPERFAMILY SSF53098 69 183 1.56E-9 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS02855 3f2a97f573b852a195d888405a07137a 226 Gene3D G3DSA:3.30.420.10 60 205 1.5E-14 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS02730 227837a4740b93c6c162ade187067d95 648 Pfam PF00367 phosphotransferase system, EIIB 9 40 3.7E-12 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CDW54_RS02730 227837a4740b93c6c162ade187067d95 648 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 18 35 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CDW54_RS02730 227837a4740b93c6c162ade187067d95 648 Gene3D G3DSA:2.70.70.10 489 648 3.1E-58 T 28-03-2018 CDW54_RS02730 227837a4740b93c6c162ade187067d95 648 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 27 108 5.3E-14 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CDW54_RS02730 227837a4740b93c6c162ade187067d95 648 Pfam PF02378 Phosphotransferase system, EIIC 111 400 8.3E-57 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CDW54_RS02730 227837a4740b93c6c162ade187067d95 648 SUPERFAMILY SSF51261 496 645 1.57E-53 T 28-03-2018 IPR011055 Duplicated hybrid motif CDW54_RS02730 227837a4740b93c6c162ade187067d95 648 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 503 623 4.5E-45 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CDW54_RS02730 227837a4740b93c6c162ade187067d95 648 TIGRFAM TIGR01996 PTS-II-BC-sucr: PTS system, sucrose-specific IIBC component 2 456 5.7E-181 T 28-03-2018 IPR010973 Phosphotransferase system, sucrose-specific IIBC component GO:0008982|GO:0009401|GO:0016021 CDW54_RS02730 227837a4740b93c6c162ade187067d95 648 Gene3D G3DSA:3.30.1360.60 4 80 2.6E-23 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CDW54_RS02730 227837a4740b93c6c162ade187067d95 648 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 502 626 2.8E-49 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CDW54_RS02730 227837a4740b93c6c162ade187067d95 648 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 565 577 - T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CDW54_RS02730 227837a4740b93c6c162ade187067d95 648 SUPERFAMILY SSF55604 7 81 1.7E-17 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CDW54_RS12100 49d428063f30473fbbc5eb7b569e83a5 259 Pfam PF03591 AzlC protein 18 158 4.7E-30 T 28-03-2018 IPR011606 Branched-chain amino acid transport, permease CDW54_RS12100 49d428063f30473fbbc5eb7b569e83a5 259 Gene3D G3DSA:1.20.1640.10 121 243 4.4E-4 T 28-03-2018 CDW54_RS06015 a296ea9379d545783b0423d7e17f1714 146 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 144 9.6E-39 T 28-03-2018 IPR021131 Ribosomal protein L18e/L15P CDW54_RS06015 a296ea9379d545783b0423d7e17f1714 146 SUPERFAMILY SSF52080 4 144 1.44E-49 T 28-03-2018 IPR021131 Ribosomal protein L18e/L15P CDW54_RS06015 a296ea9379d545783b0423d7e17f1714 146 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 144 9.1E-56 T 28-03-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS06015 a296ea9379d545783b0423d7e17f1714 146 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 146 22.552 T 28-03-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 CDW54_RS06015 a296ea9379d545783b0423d7e17f1714 146 Gene3D G3DSA:3.100.10.10 42 146 3.3E-33 T 28-03-2018 CDW54_RS06015 a296ea9379d545783b0423d7e17f1714 146 ProSitePatterns PS00475 Ribosomal protein L15 signature. 110 140 - T 28-03-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS10270 6660c22b60bce5e163e5aa8ce4c3961b 723 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 612 631 2.5E-23 T 28-03-2018 CDW54_RS10270 6660c22b60bce5e163e5aa8ce4c3961b 723 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 635 647 2.5E-23 T 28-03-2018 CDW54_RS10270 6660c22b60bce5e163e5aa8ce4c3961b 723 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 265 279 2.5E-23 T 28-03-2018 CDW54_RS10270 6660c22b60bce5e163e5aa8ce4c3961b 723 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 414 428 2.5E-23 T 28-03-2018 CDW54_RS10270 6660c22b60bce5e163e5aa8ce4c3961b 723 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 559 569 2.5E-23 T 28-03-2018 CDW54_RS10270 6660c22b60bce5e163e5aa8ce4c3961b 723 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 416 422 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CDW54_RS10270 6660c22b60bce5e163e5aa8ce4c3961b 723 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 584 600 2.1E-6 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDW54_RS10270 6660c22b60bce5e163e5aa8ce4c3961b 723 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 612 628 2.1E-6 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDW54_RS10270 6660c22b60bce5e163e5aa8ce4c3961b 723 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 643 668 2.1E-6 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDW54_RS10270 6660c22b60bce5e163e5aa8ce4c3961b 723 SUPERFAMILY SSF81665 161 218 8.11E-14 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CDW54_RS10270 6660c22b60bce5e163e5aa8ce4c3961b 723 SUPERFAMILY SSF81665 316 405 8.11E-14 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CDW54_RS10270 6660c22b60bce5e163e5aa8ce4c3961b 723 Gene3D G3DSA:3.40.50.1000 379 669 7.8E-48 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS10270 6660c22b60bce5e163e5aa8ce4c3961b 723 Pfam PF00122 E1-E2 ATPase 215 394 1.9E-48 T 28-03-2018 CDW54_RS10270 6660c22b60bce5e163e5aa8ce4c3961b 723 SUPERFAMILY SSF56784 412 432 9.82E-52 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS10270 6660c22b60bce5e163e5aa8ce4c3961b 723 SUPERFAMILY SSF56784 472 718 9.82E-52 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS10270 6660c22b60bce5e163e5aa8ce4c3961b 723 SUPERFAMILY SSF81653 222 315 2.75E-22 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CDW54_RS10270 6660c22b60bce5e163e5aa8ce4c3961b 723 Pfam PF00702 haloacid dehalogenase-like hydrolase 411 625 2.5E-34 T 28-03-2018 CDW54_RS10270 6660c22b60bce5e163e5aa8ce4c3961b 723 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 129 721 6.7E-195 T 28-03-2018 CDW54_RS10270 6660c22b60bce5e163e5aa8ce4c3961b 723 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 187 691 1.6E-79 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDW54_RS10270 6660c22b60bce5e163e5aa8ce4c3961b 723 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 147 720 7.1E-185 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CDW54_RS10270 6660c22b60bce5e163e5aa8ce4c3961b 723 Gene3D G3DSA:2.70.150.10 3 316 2.8E-29 T 28-03-2018 CDW54_RS05870 01910ac1d241616993bf94a36cab5bb7 235 SUPERFAMILY SSF53167 2 233 1.44E-87 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CDW54_RS05870 01910ac1d241616993bf94a36cab5bb7 235 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 61 76 - T 28-03-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 CDW54_RS05870 01910ac1d241616993bf94a36cab5bb7 235 TIGRFAM TIGR00107 deoD: purine nucleoside phosphorylase 4 232 3.9E-95 T 28-03-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 CDW54_RS05870 01910ac1d241616993bf94a36cab5bb7 235 Hamap MF_01627 Purine nucleoside phosphorylase DeoD-type [deoD]. 1 234 45.101 T 28-03-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 CDW54_RS05870 01910ac1d241616993bf94a36cab5bb7 235 Pfam PF01048 Phosphorylase superfamily 16 220 3.6E-38 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CDW54_RS05870 01910ac1d241616993bf94a36cab5bb7 235 Gene3D G3DSA:3.40.50.1580 8 235 2.2E-54 T 28-03-2018 CDW54_RS10205 ae0df1109c708004d615d4cfd1adf5ff 432 SUPERFAMILY SSF55681 97 431 1.39E-97 T 28-03-2018 CDW54_RS10205 ae0df1109c708004d615d4cfd1adf5ff 432 SUPERFAMILY SSF50249 9 103 7.81E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDW54_RS10205 ae0df1109c708004d615d4cfd1adf5ff 432 Pfam PF01336 OB-fold nucleic acid binding domain 17 95 4.6E-14 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CDW54_RS10205 ae0df1109c708004d615d4cfd1adf5ff 432 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 2 432 41.611 T 28-03-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 CDW54_RS10205 ae0df1109c708004d615d4cfd1adf5ff 432 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 7 431 7.8E-160 T 28-03-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 CDW54_RS10205 ae0df1109c708004d615d4cfd1adf5ff 432 Gene3D G3DSA:2.40.50.140 12 101 1.4E-19 T 28-03-2018 CDW54_RS10205 ae0df1109c708004d615d4cfd1adf5ff 432 PRINTS PR01042 Aspartyl-tRNA synthetase signature 387 401 2.0E-15 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDW54_RS10205 ae0df1109c708004d615d4cfd1adf5ff 432 PRINTS PR01042 Aspartyl-tRNA synthetase signature 197 210 2.0E-15 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDW54_RS10205 ae0df1109c708004d615d4cfd1adf5ff 432 PRINTS PR01042 Aspartyl-tRNA synthetase signature 181 193 2.0E-15 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDW54_RS10205 ae0df1109c708004d615d4cfd1adf5ff 432 PRINTS PR01042 Aspartyl-tRNA synthetase signature 347 363 2.0E-15 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDW54_RS10205 ae0df1109c708004d615d4cfd1adf5ff 432 Gene3D G3DSA:3.30.930.10 102 432 5.6E-92 T 28-03-2018 CDW54_RS10205 ae0df1109c708004d615d4cfd1adf5ff 432 Pfam PF00152 tRNA synthetases class II (D, K and N) 112 426 1.7E-80 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDW54_RS02315 0783701172da84e7aae1e630f751bfe7 373 Gene3D G3DSA:3.30.70.270 56 127 1.1E-23 T 28-03-2018 CDW54_RS02315 0783701172da84e7aae1e630f751bfe7 373 Gene3D G3DSA:3.30.70.270 128 185 3.3E-17 T 28-03-2018 CDW54_RS02315 0783701172da84e7aae1e630f751bfe7 373 SUPERFAMILY SSF100879 253 354 8.79E-25 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CDW54_RS02315 0783701172da84e7aae1e630f751bfe7 373 Pfam PF11798 IMS family HHH motif 181 212 6.4E-6 T 28-03-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CDW54_RS02315 0783701172da84e7aae1e630f751bfe7 373 SUPERFAMILY SSF56672 3 249 3.47E-93 T 28-03-2018 CDW54_RS02315 0783701172da84e7aae1e630f751bfe7 373 Gene3D G3DSA:3.30.1490.100 259 364 1.1E-27 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CDW54_RS02315 0783701172da84e7aae1e630f751bfe7 373 Hamap MF_01113 DNA polymerase IV [dinB]. 13 365 37.211 T 28-03-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CDW54_RS02315 0783701172da84e7aae1e630f751bfe7 373 Pfam PF11799 impB/mucB/samB family C-terminal domain 249 356 2.9E-17 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CDW54_RS02315 0783701172da84e7aae1e630f751bfe7 373 Gene3D G3DSA:1.10.150.20 186 258 2.0E-17 T 28-03-2018 CDW54_RS02315 0783701172da84e7aae1e630f751bfe7 373 Pfam PF00817 impB/mucB/samB family 19 169 4.8E-48 T 28-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CDW54_RS07595 217a56511cf9d4636b73ec69ee8bfd49 183 Pfam PF03551 Transcriptional regulator PadR-like family 11 85 1.3E-19 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CDW54_RS07595 217a56511cf9d4636b73ec69ee8bfd49 183 Gene3D G3DSA:1.10.10.10 1 95 2.4E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS07595 217a56511cf9d4636b73ec69ee8bfd49 183 SUPERFAMILY SSF46785 7 179 6.49E-41 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS07595 217a56511cf9d4636b73ec69ee8bfd49 183 Pfam PF10400 Virulence activator alpha C-term 98 178 1.5E-17 T 28-03-2018 IPR018309 Transcription regulator PadR, C-terminal CDW54_RS02125 5cd341b8d09a8f504be270d9c8802b20 296 SUPERFAMILY SSF48576 10 271 6.48E-79 T 28-03-2018 IPR008949 Isoprenoid synthase domain CDW54_RS02125 5cd341b8d09a8f504be270d9c8802b20 296 Pfam PF00348 Polyprenyl synthetase 31 258 1.4E-54 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 CDW54_RS02125 5cd341b8d09a8f504be270d9c8802b20 296 Gene3D G3DSA:1.10.600.10 8 291 3.3E-79 T 28-03-2018 IPR008949 Isoprenoid synthase domain CDW54_RS02125 5cd341b8d09a8f504be270d9c8802b20 296 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 211 223 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CDW54_RS02125 5cd341b8d09a8f504be270d9c8802b20 296 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 81 97 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CDW54_RS10265 57355ca7b2a5ce97caffe884c1950648 728 Pfam PF00702 haloacid dehalogenase-like hydrolase 422 634 5.8E-42 T 28-03-2018 CDW54_RS10265 57355ca7b2a5ce97caffe884c1950648 728 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 620 636 4.3E-9 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDW54_RS10265 57355ca7b2a5ce97caffe884c1950648 728 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 592 608 4.3E-9 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDW54_RS10265 57355ca7b2a5ce97caffe884c1950648 728 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 651 676 4.3E-9 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDW54_RS10265 57355ca7b2a5ce97caffe884c1950648 728 Gene3D G3DSA:3.40.50.1000 545 685 3.2E-46 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS10265 57355ca7b2a5ce97caffe884c1950648 728 SUPERFAMILY SSF81653 228 324 2.35E-32 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CDW54_RS10265 57355ca7b2a5ce97caffe884c1950648 728 SUPERFAMILY SSF55008 4 74 2.09E-19 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CDW54_RS10265 57355ca7b2a5ce97caffe884c1950648 728 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 143 722 2.0E-184 T 28-03-2018 CDW54_RS10265 57355ca7b2a5ce97caffe884c1950648 728 SUPERFAMILY SSF56784 476 720 3.92E-58 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS10265 57355ca7b2a5ce97caffe884c1950648 728 SUPERFAMILY SSF56784 423 442 3.92E-58 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS10265 57355ca7b2a5ce97caffe884c1950648 728 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 161 722 9.5E-196 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CDW54_RS10265 57355ca7b2a5ce97caffe884c1950648 728 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 426 432 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CDW54_RS10265 57355ca7b2a5ce97caffe884c1950648 728 Pfam PF00122 E1-E2 ATPase 225 404 1.9E-61 T 28-03-2018 CDW54_RS10265 57355ca7b2a5ce97caffe884c1950648 728 Pfam PF00403 Heavy-metal-associated domain 11 68 1.8E-15 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CDW54_RS10265 57355ca7b2a5ce97caffe884c1950648 728 Gene3D G3DSA:3.40.1110.10 439 544 7.4E-27 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CDW54_RS10265 57355ca7b2a5ce97caffe884c1950648 728 Gene3D G3DSA:3.30.70.100 6 82 2.7E-20 T 28-03-2018 CDW54_RS10265 57355ca7b2a5ce97caffe884c1950648 728 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 543 554 1.0E-27 T 28-03-2018 CDW54_RS10265 57355ca7b2a5ce97caffe884c1950648 728 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 274 288 1.0E-27 T 28-03-2018 CDW54_RS10265 57355ca7b2a5ce97caffe884c1950648 728 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 424 438 1.0E-27 T 28-03-2018 CDW54_RS10265 57355ca7b2a5ce97caffe884c1950648 728 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 643 655 1.0E-27 T 28-03-2018 CDW54_RS10265 57355ca7b2a5ce97caffe884c1950648 728 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 565 575 1.0E-27 T 28-03-2018 CDW54_RS10265 57355ca7b2a5ce97caffe884c1950648 728 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 620 639 1.0E-27 T 28-03-2018 CDW54_RS10265 57355ca7b2a5ce97caffe884c1950648 728 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 196 700 3.5E-102 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDW54_RS10265 57355ca7b2a5ce97caffe884c1950648 728 ProSitePatterns PS01047 Heavy-metal-associated domain. 13 42 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CDW54_RS10265 57355ca7b2a5ce97caffe884c1950648 728 SUPERFAMILY SSF81665 173 228 2.22E-16 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CDW54_RS10265 57355ca7b2a5ce97caffe884c1950648 728 SUPERFAMILY SSF81665 325 418 2.22E-16 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CDW54_RS10265 57355ca7b2a5ce97caffe884c1950648 728 SUPERFAMILY SSF81665 669 699 2.22E-16 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CDW54_RS10265 57355ca7b2a5ce97caffe884c1950648 728 Gene3D G3DSA:1.20.1110.10 191 438 9.9E-54 T 28-03-2018 CDW54_RS08780 8d6c9772b6d660a6cc0cc34bacfcd236 233 Pfam PF07702 UTRA domain 96 223 2.6E-16 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CDW54_RS08780 8d6c9772b6d660a6cc0cc34bacfcd236 233 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 30 44 2.3E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDW54_RS08780 8d6c9772b6d660a6cc0cc34bacfcd236 233 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 60 2.3E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDW54_RS08780 8d6c9772b6d660a6cc0cc34bacfcd236 233 SUPERFAMILY SSF64288 59 231 9.42E-25 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CDW54_RS08780 8d6c9772b6d660a6cc0cc34bacfcd236 233 SMART SM00345 11 70 3.8E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDW54_RS08780 8d6c9772b6d660a6cc0cc34bacfcd236 233 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 70 3.2E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDW54_RS08780 8d6c9772b6d660a6cc0cc34bacfcd236 233 SUPERFAMILY SSF46785 5 79 2.5E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS08780 8d6c9772b6d660a6cc0cc34bacfcd236 233 Gene3D G3DSA:1.10.10.10 1 72 6.4E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS08780 8d6c9772b6d660a6cc0cc34bacfcd236 233 Gene3D G3DSA:3.40.1410.10 77 231 2.2E-19 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CDW54_RS08780 8d6c9772b6d660a6cc0cc34bacfcd236 233 SMART SM00866 91 226 7.7E-7 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CDW54_RS01265 53bbf7b7790ad30656765418c1b96524 291 SUPERFAMILY SSF63520 73 182 1.16E-25 T 28-03-2018 IPR011608 PRD domain GO:0006355 CDW54_RS01265 53bbf7b7790ad30656765418c1b96524 291 SUPERFAMILY SSF63520 190 290 6.15E-20 T 28-03-2018 IPR011608 PRD domain GO:0006355 CDW54_RS01265 53bbf7b7790ad30656765418c1b96524 291 Gene3D G3DSA:1.10.1790.10 82 184 9.0E-22 T 28-03-2018 IPR011608 PRD domain GO:0006355 CDW54_RS01265 53bbf7b7790ad30656765418c1b96524 291 Pfam PF00874 PRD domain 199 289 4.4E-15 T 28-03-2018 IPR011608 PRD domain GO:0006355 CDW54_RS01265 53bbf7b7790ad30656765418c1b96524 291 Pfam PF00874 PRD domain 92 179 2.0E-17 T 28-03-2018 IPR011608 PRD domain GO:0006355 CDW54_RS01265 53bbf7b7790ad30656765418c1b96524 291 Pfam PF03123 CAT RNA binding domain 21 72 4.3E-15 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CDW54_RS01265 53bbf7b7790ad30656765418c1b96524 291 SMART SM01061 19 76 1.8E-9 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CDW54_RS01265 53bbf7b7790ad30656765418c1b96524 291 Gene3D G3DSA:2.30.24.10 17 81 8.2E-17 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CDW54_RS01265 53bbf7b7790ad30656765418c1b96524 291 SUPERFAMILY SSF50151 20 71 1.05E-12 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CDW54_RS01265 53bbf7b7790ad30656765418c1b96524 291 Gene3D G3DSA:1.10.1790.10 186 291 3.7E-17 T 28-03-2018 IPR011608 PRD domain GO:0006355 CDW54_RS05260 c82d3c9e8be7deb0292a2c6f23e5c43a 147 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 5 143 5.2E-62 T 28-03-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS05260 c82d3c9e8be7deb0292a2c6f23e5c43a 147 Pfam PF00572 Ribosomal protein L13 15 139 8.3E-56 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CDW54_RS05260 c82d3c9e8be7deb0292a2c6f23e5c43a 147 SUPERFAMILY SSF52161 5 144 1.07E-58 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CDW54_RS05260 c82d3c9e8be7deb0292a2c6f23e5c43a 147 Gene3D G3DSA:3.90.1180.10 1 146 4.3E-60 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CDW54_RS05260 c82d3c9e8be7deb0292a2c6f23e5c43a 147 PIRSF PIRSF002181 1 146 2.3E-48 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CDW54_RS05260 c82d3c9e8be7deb0292a2c6f23e5c43a 147 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 16 142 26.922 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CDW54_RS05260 c82d3c9e8be7deb0292a2c6f23e5c43a 147 ProSitePatterns PS00783 Ribosomal protein L13 signature. 106 128 - T 28-03-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 CDW54_RS01995 237cb9918af60dd8dc61ee2d77574ae0 242 Pfam PF03749 Sugar fermentation stimulation protein 12 224 4.6E-63 T 28-03-2018 IPR005224 Sugar fermentation stimulation protein CDW54_RS01995 237cb9918af60dd8dc61ee2d77574ae0 242 Hamap MF_00095 Sugar fermentation stimulation protein A [sfsA]. 1 233 43.003 T 28-03-2018 IPR005224 Sugar fermentation stimulation protein CDW54_RS01995 237cb9918af60dd8dc61ee2d77574ae0 242 TIGRFAM TIGR00230 sfsA: sugar fermentation stimulation protein 7 226 1.3E-48 T 28-03-2018 IPR005224 Sugar fermentation stimulation protein CDW54_RS03590 0c91feced4061b53f9fce26017e10d1d 505 Gene3D G3DSA:3.20.20.80 17 371 1.8E-113 T 28-03-2018 CDW54_RS03590 0c91feced4061b53f9fce26017e10d1d 505 Gene3D G3DSA:2.60.40.1180 372 495 3.4E-29 T 28-03-2018 CDW54_RS03590 0c91feced4061b53f9fce26017e10d1d 505 Pfam PF06964 Alpha-L-arabinofuranosidase C-terminal domain 290 487 3.5E-38 T 28-03-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 CDW54_RS03590 0c91feced4061b53f9fce26017e10d1d 505 SUPERFAMILY SSF51445 16 379 9.46E-112 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CDW54_RS03590 0c91feced4061b53f9fce26017e10d1d 505 SMART SM00813 290 487 3.3E-79 T 28-03-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 CDW54_RS03590 0c91feced4061b53f9fce26017e10d1d 505 SUPERFAMILY SSF51011 369 493 8.99E-35 T 28-03-2018 CDW54_RS00050 07312c928df93a8513445be566713f41 1175 Gene3D G3DSA:3.40.50.300 1 140 1.4E-22 T 28-03-2018 CDW54_RS00050 07312c928df93a8513445be566713f41 1175 Gene3D G3DSA:3.40.50.300 141 274 3.4E-23 T 28-03-2018 CDW54_RS00050 07312c928df93a8513445be566713f41 1175 SUPERFAMILY SSF52540 306 719 5.71E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS00050 07312c928df93a8513445be566713f41 1175 Pfam PF12705 PD-(D/E)XK nuclease superfamily 797 1142 7.9E-43 T 28-03-2018 CDW54_RS00050 07312c928df93a8513445be566713f41 1175 Hamap MF_01453 ATP-dependent helicase/deoxyribonuclease subunit B [rexB]. 3 1174 37.558 T 28-03-2018 IPR014141 DNA helicase subunit RexB GO:0016788|GO:0016817 CDW54_RS00050 07312c928df93a8513445be566713f41 1175 Gene3D G3DSA:3.40.50.300 280 791 3.7E-31 T 28-03-2018 CDW54_RS11370 a1844f3ec25c4b7f5b7b9992b818de86 463 Gene3D G3DSA:1.10.3860.10 19 450 4.0E-85 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDW54_RS11370 a1844f3ec25c4b7f5b7b9992b818de86 463 PRINTS PR00173 Glutamate-aspartate symporter signature 370 389 8.8E-20 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDW54_RS11370 a1844f3ec25c4b7f5b7b9992b818de86 463 PRINTS PR00173 Glutamate-aspartate symporter signature 76 96 8.8E-20 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDW54_RS11370 a1844f3ec25c4b7f5b7b9992b818de86 463 PRINTS PR00173 Glutamate-aspartate symporter signature 106 131 8.8E-20 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDW54_RS11370 a1844f3ec25c4b7f5b7b9992b818de86 463 PRINTS PR00173 Glutamate-aspartate symporter signature 182 204 8.8E-20 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDW54_RS11370 a1844f3ec25c4b7f5b7b9992b818de86 463 PRINTS PR00173 Glutamate-aspartate symporter signature 28 48 8.8E-20 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDW54_RS11370 a1844f3ec25c4b7f5b7b9992b818de86 463 PRINTS PR00173 Glutamate-aspartate symporter signature 397 417 8.8E-20 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDW54_RS11370 a1844f3ec25c4b7f5b7b9992b818de86 463 Pfam PF00375 Sodium:dicarboxylate symporter family 31 441 2.1E-98 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDW54_RS11370 a1844f3ec25c4b7f5b7b9992b818de86 463 SUPERFAMILY SSF118215 30 441 1.02E-89 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDW54_RS10375 bd752952b03ed5d6ee4d90ee27f9978d 472 Pfam PF02881 SRP54-type protein, helical bundle domain 6 83 6.0E-22 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CDW54_RS10375 bd752952b03ed5d6ee4d90ee27f9978d 472 SUPERFAMILY SSF52540 43 354 7.36E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS10375 bd752952b03ed5d6ee4d90ee27f9978d 472 Gene3D G3DSA:3.40.50.300 101 298 8.9E-41 T 28-03-2018 CDW54_RS10375 bd752952b03ed5d6ee4d90ee27f9978d 472 TIGRFAM TIGR00959 ffh: signal recognition particle protein 3 429 2.4E-190 T 28-03-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 CDW54_RS10375 bd752952b03ed5d6ee4d90ee27f9978d 472 Gene3D G3DSA:1.20.120.140 1 92 1.6E-27 T 28-03-2018 CDW54_RS10375 bd752952b03ed5d6ee4d90ee27f9978d 472 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 6 461 35.015 T 28-03-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 CDW54_RS10375 bd752952b03ed5d6ee4d90ee27f9978d 472 SMART SM00963 2 87 1.5E-29 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CDW54_RS10375 bd752952b03ed5d6ee4d90ee27f9978d 472 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 270 283 - T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CDW54_RS10375 bd752952b03ed5d6ee4d90ee27f9978d 472 SMART SM00382 100 302 5.9E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS10375 bd752952b03ed5d6ee4d90ee27f9978d 472 Pfam PF02978 Signal peptide binding domain 329 427 4.6E-31 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CDW54_RS10375 bd752952b03ed5d6ee4d90ee27f9978d 472 SMART SM00962 101 297 6.7E-122 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CDW54_RS10375 bd752952b03ed5d6ee4d90ee27f9978d 472 Gene3D G3DSA:1.10.260.30 328 432 5.5E-37 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CDW54_RS10375 bd752952b03ed5d6ee4d90ee27f9978d 472 Pfam PF00448 SRP54-type protein, GTPase domain 101 297 8.5E-79 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CDW54_RS10375 bd752952b03ed5d6ee4d90ee27f9978d 472 SUPERFAMILY SSF47446 329 431 8.01E-36 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CDW54_RS08885 427b74b108b439ced4d043b1c5d4b1c1 407 Gene3D G3DSA:3.40.630.10 2 254 1.9E-42 T 28-03-2018 CDW54_RS08885 427b74b108b439ced4d043b1c5d4b1c1 407 SUPERFAMILY SSF55031 176 280 4.32E-23 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CDW54_RS08885 427b74b108b439ced4d043b1c5d4b1c1 407 Pfam PF07687 Peptidase dimerisation domain 177 268 1.2E-11 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CDW54_RS08885 427b74b108b439ced4d043b1c5d4b1c1 407 PIRSF PIRSF037226 1 403 1.8E-142 T 28-03-2018 IPR017144 Peptidase M20A, amidohydrolase, predicted CDW54_RS08885 427b74b108b439ced4d043b1c5d4b1c1 407 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 24 357 4.9E-65 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CDW54_RS08885 427b74b108b439ced4d043b1c5d4b1c1 407 Gene3D G3DSA:3.40.630.10 255 396 3.9E-17 T 28-03-2018 CDW54_RS08885 427b74b108b439ced4d043b1c5d4b1c1 407 SUPERFAMILY SSF53187 287 384 5.09E-53 T 28-03-2018 CDW54_RS08885 427b74b108b439ced4d043b1c5d4b1c1 407 SUPERFAMILY SSF53187 9 187 5.09E-53 T 28-03-2018 CDW54_RS12055 d64502aae9e8daf22347d1b2cc569523 182 Gene3D G3DSA:3.40.50.300 2 33 7.2E-5 T 28-03-2018 CDW54_RS12055 d64502aae9e8daf22347d1b2cc569523 182 Gene3D G3DSA:3.30.63.10 34 74 7.8E-20 T 28-03-2018 CDW54_RS12055 d64502aae9e8daf22347d1b2cc569523 182 Pfam PF00625 Guanylate kinase 4 150 5.5E-23 T 28-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CDW54_RS12055 d64502aae9e8daf22347d1b2cc569523 182 Gene3D G3DSA:3.40.50.300 75 180 2.2E-8 T 28-03-2018 CDW54_RS12055 d64502aae9e8daf22347d1b2cc569523 182 SUPERFAMILY SSF52540 4 178 1.86E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS12055 d64502aae9e8daf22347d1b2cc569523 182 SMART SM00072 1 180 4.1E-6 T 28-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CDW54_RS09975 60df3b534e1f2ed6a67e88eff2b52c78 58 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 22.076 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS09975 60df3b534e1f2ed6a67e88eff2b52c78 58 Pfam PF01165 Ribosomal protein S21 5 56 5.2E-20 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS09975 60df3b534e1f2ed6a67e88eff2b52c78 58 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 2.2E-15 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS09975 60df3b534e1f2ed6a67e88eff2b52c78 58 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 2.2E-15 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS09975 60df3b534e1f2ed6a67e88eff2b52c78 58 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 2.2E-15 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS09975 60df3b534e1f2ed6a67e88eff2b52c78 58 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 2.2E-15 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS09975 60df3b534e1f2ed6a67e88eff2b52c78 58 Gene3D G3DSA:1.20.5.1150 16 52 1.2E-17 T 28-03-2018 CDW54_RS09975 60df3b534e1f2ed6a67e88eff2b52c78 58 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 3 56 7.0E-22 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS09975 60df3b534e1f2ed6a67e88eff2b52c78 58 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 28-03-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS09975 60df3b534e1f2ed6a67e88eff2b52c78 58 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 16 43 9.0E-9 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS02820 4414886883600df3ef34f3adab57bfb9 103 Gene3D G3DSA:1.10.10.10 2 94 3.7E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS02820 4414886883600df3ef34f3adab57bfb9 103 Pfam PF03551 Transcriptional regulator PadR-like family 16 85 7.3E-12 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CDW54_RS02820 4414886883600df3ef34f3adab57bfb9 103 SUPERFAMILY SSF46785 8 95 1.22E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS05645 6b6316f5c7e34d75d09f3b36e6cd9ecb 252 Pfam PF01424 R3H domain 188 246 5.2E-16 T 28-03-2018 IPR001374 R3H domain GO:0003676 CDW54_RS05645 6b6316f5c7e34d75d09f3b36e6cd9ecb 252 SMART SM00393 169 248 2.9E-17 T 28-03-2018 IPR001374 R3H domain GO:0003676 CDW54_RS05645 6b6316f5c7e34d75d09f3b36e6cd9ecb 252 Gene3D G3DSA:3.30.300.20 100 183 4.2E-16 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CDW54_RS05645 6b6316f5c7e34d75d09f3b36e6cd9ecb 252 Pfam PF13083 KH domain 115 175 7.9E-12 T 28-03-2018 CDW54_RS05645 6b6316f5c7e34d75d09f3b36e6cd9ecb 252 SMART SM01245 3 54 1.2E-17 T 28-03-2018 IPR032782 Jag, N-terminal CDW54_RS05645 6b6316f5c7e34d75d09f3b36e6cd9ecb 252 SUPERFAMILY SSF82708 199 247 3.73E-8 T 28-03-2018 IPR001374 R3H domain GO:0003676 CDW54_RS05645 6b6316f5c7e34d75d09f3b36e6cd9ecb 252 Gene3D G3DSA:3.30.30.80 3 51 9.0E-18 T 28-03-2018 CDW54_RS05645 6b6316f5c7e34d75d09f3b36e6cd9ecb 252 Pfam PF14804 Jag N-terminus 4 49 2.4E-17 T 28-03-2018 IPR032782 Jag, N-terminal CDW54_RS05645 6b6316f5c7e34d75d09f3b36e6cd9ecb 252 SMART SM00322 129 197 0.0062 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CDW54_RS05645 6b6316f5c7e34d75d09f3b36e6cd9ecb 252 Gene3D G3DSA:3.30.1370.50 184 251 1.3E-19 T 28-03-2018 IPR001374 R3H domain GO:0003676 CDW54_RS00705 19042685781f4dcac10c7b59d2330343 253 ProSitePatterns PS01087 Radical activating enzymes signature. 20 41 - T 28-03-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 CDW54_RS00705 19042685781f4dcac10c7b59d2330343 253 Pfam PF04055 Radical SAM superfamily 26 185 2.1E-29 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CDW54_RS00705 19042685781f4dcac10c7b59d2330343 253 Pfam PF13353 4Fe-4S single cluster domain 18 146 1.9E-22 T 28-03-2018 CDW54_RS00705 19042685781f4dcac10c7b59d2330343 253 SUPERFAMILY SSF102114 25 226 3.14E-29 T 28-03-2018 CDW54_RS00705 19042685781f4dcac10c7b59d2330343 253 TIGRFAM TIGR02493 PFLA: pyruvate formate-lyase 1-activating enzyme 8 243 2.1E-96 T 28-03-2018 IPR012838 Pyruvate formate-lyase activating enzyme GO:0043365|GO:0055114 CDW54_RS00705 19042685781f4dcac10c7b59d2330343 253 PIRSF PIRSF000371 1 49 1.1E-14 T 28-03-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 CDW54_RS00705 19042685781f4dcac10c7b59d2330343 253 PIRSF PIRSF000371 47 253 1.7E-42 T 28-03-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 CDW54_RS00705 19042685781f4dcac10c7b59d2330343 253 Gene3D G3DSA:3.80.30.10 70 252 1.8E-39 T 28-03-2018 CDW54_RS11575 e076fb10a4bd812eadd168ac9235f5a3 227 Gene3D G3DSA:3.40.50.880 1 226 3.3E-37 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CDW54_RS11575 e076fb10a4bd812eadd168ac9235f5a3 227 SUPERFAMILY SSF52317 2 224 4.58E-56 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CDW54_RS11575 e076fb10a4bd812eadd168ac9235f5a3 227 Pfam PF01965 DJ-1/PfpI family 86 224 2.5E-8 T 28-03-2018 IPR002818 DJ-1/PfpI CDW54_RS02180 9d31c864541112976aadb16bafd8346c 329 Pfam PF03830 PTS system sorbose subfamily IIB component 166 311 2.0E-51 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 CDW54_RS02180 9d31c864541112976aadb16bafd8346c 329 SUPERFAMILY SSF52728 164 322 8.37E-55 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 CDW54_RS02180 9d31c864541112976aadb16bafd8346c 329 Gene3D G3DSA:3.40.35.10 164 320 1.9E-56 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 CDW54_RS02180 9d31c864541112976aadb16bafd8346c 329 Pfam PF03610 PTS system fructose IIA component 3 118 4.5E-35 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CDW54_RS02180 9d31c864541112976aadb16bafd8346c 329 Gene3D G3DSA:3.40.50.510 1 146 5.5E-41 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CDW54_RS02180 9d31c864541112976aadb16bafd8346c 329 TIGRFAM TIGR00854 pts-sorbose: PTS system, mannose/fructose/sorbose family, IIB component 166 312 6.3E-49 T 28-03-2018 IPR018455 Phosphotransferase system, sorbose subfamily IIB component, subgroup GO:0005737|GO:0008982|GO:0009401 CDW54_RS02180 9d31c864541112976aadb16bafd8346c 329 SUPERFAMILY SSF53062 1 128 6.8E-39 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CDW54_RS02180 9d31c864541112976aadb16bafd8346c 329 TIGRFAM TIGR00824 EIIA-man: PTS system, mannose/fructose/sorbose family, IIA component 1 114 1.1E-30 T 28-03-2018 IPR013789 Phosphotransferase system, mannose family IIA component GO:0005737|GO:0008643|GO:0016773 CDW54_RS04915 5d9fdc0239966cb52d9d346d35ed00f4 101 SMART SM01409 9 62 2.7E-12 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CDW54_RS04915 5d9fdc0239966cb52d9d346d35ed00f4 101 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 2 63 14.507 T 28-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDW54_RS04915 5d9fdc0239966cb52d9d346d35ed00f4 101 Pfam PF01192 RNA polymerase Rpb6 10 59 1.6E-10 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CDW54_RS04915 5d9fdc0239966cb52d9d346d35ed00f4 101 Gene3D G3DSA:3.90.940.10 2 101 7.5E-28 T 28-03-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CDW54_RS04915 5d9fdc0239966cb52d9d346d35ed00f4 101 SUPERFAMILY SSF63562 2 83 1.29E-23 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CDW54_RS04915 5d9fdc0239966cb52d9d346d35ed00f4 101 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 2 60 7.9E-16 T 28-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDW54_RS04460 6bf5f9eb95340e23561939e06b9a4dab 239 Gene3D G3DSA:3.30.2350.10 70 239 1.3E-39 T 28-03-2018 CDW54_RS04460 6bf5f9eb95340e23561939e06b9a4dab 239 SUPERFAMILY SSF55174 1 58 3.53E-12 T 28-03-2018 CDW54_RS04460 6bf5f9eb95340e23561939e06b9a4dab 239 Pfam PF01479 S4 domain 1 42 1.2E-10 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDW54_RS04460 6bf5f9eb95340e23561939e06b9a4dab 239 Gene3D G3DSA:3.10.290.10 1 69 8.1E-17 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDW54_RS04460 6bf5f9eb95340e23561939e06b9a4dab 239 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 100 114 - T 28-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 CDW54_RS04460 6bf5f9eb95340e23561939e06b9a4dab 239 SUPERFAMILY SSF55120 46 236 2.88E-45 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDW54_RS04460 6bf5f9eb95340e23561939e06b9a4dab 239 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 230 2.2E-44 T 28-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 CDW54_RS04460 6bf5f9eb95340e23561939e06b9a4dab 239 SMART SM00363 1 59 1.3E-7 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDW54_RS04460 6bf5f9eb95340e23561939e06b9a4dab 239 Pfam PF00849 RNA pseudouridylate synthase 62 197 2.3E-20 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDW54_RS05085 9bb43e6e7ace1645fdc27ff6b1a235de 470 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 193 211 1.2E-29 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CDW54_RS05085 9bb43e6e7ace1645fdc27ff6b1a235de 470 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 25 36 1.2E-29 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CDW54_RS05085 9bb43e6e7ace1645fdc27ff6b1a235de 470 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 61 70 1.2E-29 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CDW54_RS05085 9bb43e6e7ace1645fdc27ff6b1a235de 470 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 224 245 1.2E-29 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CDW54_RS05085 9bb43e6e7ace1645fdc27ff6b1a235de 470 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 17 316 1.6E-132 T 28-03-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 CDW54_RS05085 9bb43e6e7ace1645fdc27ff6b1a235de 470 SUPERFAMILY SSF52374 2 316 4.35E-103 T 28-03-2018 CDW54_RS05085 9bb43e6e7ace1645fdc27ff6b1a235de 470 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 2 468 1.6E-177 T 28-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 CDW54_RS05085 9bb43e6e7ace1645fdc27ff6b1a235de 470 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 2 469 38.809 T 28-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 CDW54_RS05085 9bb43e6e7ace1645fdc27ff6b1a235de 470 SMART SM00840 357 420 5.4E-17 T 28-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 CDW54_RS05085 9bb43e6e7ace1645fdc27ff6b1a235de 470 Pfam PF09190 DALR domain 357 418 6.4E-16 T 28-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 CDW54_RS05085 9bb43e6e7ace1645fdc27ff6b1a235de 470 SUPERFAMILY SSF47323 342 468 3.27E-33 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDW54_RS05085 9bb43e6e7ace1645fdc27ff6b1a235de 470 Gene3D G3DSA:1.20.120.640 310 411 5.7E-17 T 28-03-2018 CDW54_RS05085 9bb43e6e7ace1645fdc27ff6b1a235de 470 Gene3D G3DSA:3.40.50.620 1 309 1.0E-94 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDW54_RS12050 aa3c8bdd243bd49c7069094c3f85987b 170 SUPERFAMILY SSF55729 3 155 4.43E-19 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDW54_RS12050 aa3c8bdd243bd49c7069094c3f85987b 170 Gene3D G3DSA:3.40.630.30 1 170 5.9E-21 T 28-03-2018 CDW54_RS12050 aa3c8bdd243bd49c7069094c3f85987b 170 Pfam PF00583 Acetyltransferase (GNAT) family 33 147 2.2E-6 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CDW54_RS04145 70af36dda181e1300fa6231ebeebf47c 335 Pfam PF02384 N-6 DNA Methylase 99 317 2.4E-13 T 28-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 CDW54_RS04145 70af36dda181e1300fa6231ebeebf47c 335 PIRSF PIRSF026567 1 335 2.5E-135 T 28-03-2018 IPR016843 S-adenosyl-L-methionine dependent adenine methyltransferase, bacteria, predicted CDW54_RS04145 70af36dda181e1300fa6231ebeebf47c 335 Gene3D G3DSA:3.40.50.150 92 335 3.9E-34 T 28-03-2018 CDW54_RS04145 70af36dda181e1300fa6231ebeebf47c 335 SUPERFAMILY SSF53335 27 324 1.4E-43 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDW54_RS01470 156eb8ee514048c4d08c5c0bbbf37c2a 759 Pfam PF13538 UvrD-like helicase C-terminal domain 696 736 1.2E-7 T 28-03-2018 IPR027785 UvrD-like helicase C-terminal domain CDW54_RS01470 156eb8ee514048c4d08c5c0bbbf37c2a 759 SUPERFAMILY SSF52540 197 348 1.1E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS01470 156eb8ee514048c4d08c5c0bbbf37c2a 759 SUPERFAMILY SSF52540 475 741 1.1E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS01470 156eb8ee514048c4d08c5c0bbbf37c2a 759 Gene3D G3DSA:3.40.50.300 203 566 8.0E-28 T 28-03-2018 CDW54_RS01470 156eb8ee514048c4d08c5c0bbbf37c2a 759 Pfam PF13361 UvrD-like helicase C-terminal domain 583 689 2.9E-6 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CDW54_RS01470 156eb8ee514048c4d08c5c0bbbf37c2a 759 Gene3D G3DSA:3.40.50.300 584 758 5.4E-26 T 28-03-2018 CDW54_RS01470 156eb8ee514048c4d08c5c0bbbf37c2a 759 Pfam PF13245 AAA domain 209 561 5.8E-12 T 28-03-2018 CDW54_RS02205 b0fd1966ea8ccee9c37090787e0a2fcb 102 SUPERFAMILY SSF141091 1 101 5.89E-38 T 28-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS02205 b0fd1966ea8ccee9c37090787e0a2fcb 102 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 100 1.6E-38 T 28-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS02205 b0fd1966ea8ccee9c37090787e0a2fcb 102 ProSitePatterns PS01169 Ribosomal protein L21 signature. 71 93 - T 28-03-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS02205 b0fd1966ea8ccee9c37090787e0a2fcb 102 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 102 25.763 T 28-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS02205 b0fd1966ea8ccee9c37090787e0a2fcb 102 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 100 2.0E-37 T 28-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS00035 b939b00c01754fc8b20c33d07a5d08d7 347 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 42 345 1.0E-110 T 28-03-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CDW54_RS00035 b939b00c01754fc8b20c33d07a5d08d7 347 SUPERFAMILY SSF55681 95 345 3.04E-82 T 28-03-2018 CDW54_RS00035 b939b00c01754fc8b20c33d07a5d08d7 347 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 22 90 1.1E-24 T 28-03-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CDW54_RS00035 b939b00c01754fc8b20c33d07a5d08d7 347 Gene3D G3DSA:3.30.930.10 10 347 2.0E-96 T 28-03-2018 CDW54_RS00035 b939b00c01754fc8b20c33d07a5d08d7 347 SUPERFAMILY SSF46589 15 102 3.24E-22 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 CDW54_RS00035 b939b00c01754fc8b20c33d07a5d08d7 347 Pfam PF01409 tRNA synthetases class II core domain (F) 95 344 7.2E-109 T 28-03-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 CDW54_RS00035 b939b00c01754fc8b20c33d07a5d08d7 347 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 11 344 47.957 T 28-03-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 CDW54_RS04360 c77f350293c868817b9c1ffcb798ff4d 464 Gene3D G3DSA:3.20.20.140 88 462 2.3E-141 T 28-03-2018 CDW54_RS04360 c77f350293c868817b9c1ffcb798ff4d 464 Hamap MF_00675 Uronate isomerase [uxaC]. 1 462 46.226 T 28-03-2018 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 CDW54_RS04360 c77f350293c868817b9c1ffcb798ff4d 464 Pfam PF02614 Glucuronate isomerase 2 460 3.6E-207 T 28-03-2018 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 CDW54_RS04360 c77f350293c868817b9c1ffcb798ff4d 464 SUPERFAMILY SSF51556 1 461 1.7E-176 T 28-03-2018 IPR032466 Metal-dependent hydrolase CDW54_RS04360 c77f350293c868817b9c1ffcb798ff4d 464 Gene3D G3DSA:3.20.20.140 1 87 1.0E-27 T 28-03-2018 CDW54_RS10665 4103ba98ffb63133571480c9036d58ac 148 Pfam PF09954 Uncharacterized protein conserved in bacteria (DUF2188) 93 148 4.0E-14 T 28-03-2018 IPR018691 Protein of unknown function DUF2188 CDW54_RS05765 69f5c51b73bbf9c4226f2d2073340895 576 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 196 322 4.0E-31 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CDW54_RS05765 69f5c51b73bbf9c4226f2d2073340895 576 Gene3D G3DSA:3.40.50.1220 191 344 2.1E-31 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CDW54_RS05765 69f5c51b73bbf9c4226f2d2073340895 576 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 6 173 1.4E-42 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CDW54_RS05765 69f5c51b73bbf9c4226f2d2073340895 576 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 382 528 3.9E-32 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CDW54_RS05765 69f5c51b73bbf9c4226f2d2073340895 576 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 419 438 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CDW54_RS05765 69f5c51b73bbf9c4226f2d2073340895 576 Gene3D G3DSA:3.40.50.970 1 190 1.8E-43 T 28-03-2018 CDW54_RS05765 69f5c51b73bbf9c4226f2d2073340895 576 Gene3D G3DSA:3.40.50.970 345 540 3.7E-34 T 28-03-2018 CDW54_RS05765 69f5c51b73bbf9c4226f2d2073340895 576 SUPERFAMILY SSF52518 358 573 3.86E-53 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CDW54_RS05765 69f5c51b73bbf9c4226f2d2073340895 576 SUPERFAMILY SSF52467 186 353 4.3E-40 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CDW54_RS05765 69f5c51b73bbf9c4226f2d2073340895 576 SUPERFAMILY SSF52518 4 175 1.77E-45 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CDW54_RS05765 69f5c51b73bbf9c4226f2d2073340895 576 TIGRFAM TIGR02720 pyruv_oxi_spxB: pyruvate oxidase 6 569 4.3E-241 T 28-03-2018 IPR014092 Pyruvate oxidase GO:0047112|GO:0055114 KEGG: 00620+1.2.3.3 CDW54_RS06435 9f880522afc731d05d66a94a67392f42 246 SMART SM00382 30 217 7.5E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS06435 9f880522afc731d05d66a94a67392f42 246 PIRSF PIRSF039085 2 245 8.1E-113 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CDW54_RS06435 9f880522afc731d05d66a94a67392f42 246 Gene3D G3DSA:3.40.50.300 1 245 9.8E-78 T 28-03-2018 CDW54_RS06435 9f880522afc731d05d66a94a67392f42 246 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS06435 9f880522afc731d05d66a94a67392f42 246 Pfam PF00005 ABC transporter 21 169 7.0E-37 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS06435 9f880522afc731d05d66a94a67392f42 246 SUPERFAMILY SSF52540 5 239 2.72E-79 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS05245 1fef2b86c0ac286746293ad11047162f 305 SUPERFAMILY SSF52540 7 223 2.37E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS05245 1fef2b86c0ac286746293ad11047162f 305 SMART SM00382 33 211 7.0E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS05245 1fef2b86c0ac286746293ad11047162f 305 Gene3D G3DSA:3.40.50.300 5 277 2.2E-56 T 28-03-2018 CDW54_RS05245 1fef2b86c0ac286746293ad11047162f 305 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS05245 1fef2b86c0ac286746293ad11047162f 305 Pfam PF00005 ABC transporter 24 161 7.0E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS08330 7e207c26ff11d6a03fb276907a4a6534 282 Gene3D G3DSA:3.40.190.10 38 150 3.4E-38 T 28-03-2018 CDW54_RS08330 7e207c26ff11d6a03fb276907a4a6534 282 Gene3D G3DSA:3.40.190.10 151 282 6.5E-38 T 28-03-2018 CDW54_RS08330 7e207c26ff11d6a03fb276907a4a6534 282 SUPERFAMILY SSF53850 38 278 3.75E-79 T 28-03-2018 CDW54_RS08330 7e207c26ff11d6a03fb276907a4a6534 282 Pfam PF03180 NLPA lipoprotein 39 277 1.5E-83 T 28-03-2018 IPR004872 Lipoprotein NlpA family CDW54_RS08330 7e207c26ff11d6a03fb276907a4a6534 282 PIRSF PIRSF002854 1 278 6.0E-99 T 28-03-2018 IPR004872 Lipoprotein NlpA family CDW54_RS05670 f53d25a66d2dc040ba25bd05916370e2 444 Pfam PF11638 DnaA N-terminal domain 6 62 6.0E-8 T 28-03-2018 IPR024633 DnaA N-terminal domain CDW54_RS05670 f53d25a66d2dc040ba25bd05916370e2 444 ProSitePatterns PS01008 DnaA protein signature. 402 421 - T 28-03-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CDW54_RS05670 f53d25a66d2dc040ba25bd05916370e2 444 SMART SM00382 140 271 2.1E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS05670 f53d25a66d2dc040ba25bd05916370e2 444 Gene3D G3DSA:1.10.8.60 274 345 2.1E-24 T 28-03-2018 CDW54_RS05670 f53d25a66d2dc040ba25bd05916370e2 444 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 8 441 9.9E-176 T 28-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CDW54_RS05670 f53d25a66d2dc040ba25bd05916370e2 444 Gene3D G3DSA:1.10.1750.10 346 442 6.0E-34 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CDW54_RS05670 f53d25a66d2dc040ba25bd05916370e2 444 Pfam PF00308 Bacterial dnaA protein 108 324 1.4E-98 T 28-03-2018 IPR013317 Chromosomal replication initiator protein DnaA CDW54_RS05670 f53d25a66d2dc040ba25bd05916370e2 444 SMART SM00760 352 421 6.0E-42 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CDW54_RS05670 f53d25a66d2dc040ba25bd05916370e2 444 SUPERFAMILY SSF48295 349 443 1.44E-34 T 28-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 CDW54_RS05670 f53d25a66d2dc040ba25bd05916370e2 444 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 355 421 1.2E-31 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CDW54_RS05670 f53d25a66d2dc040ba25bd05916370e2 444 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 5 443 32.968 T 28-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CDW54_RS05670 f53d25a66d2dc040ba25bd05916370e2 444 SUPERFAMILY SSF52540 108 318 3.25E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS05670 f53d25a66d2dc040ba25bd05916370e2 444 Gene3D G3DSA:3.40.50.300 105 272 3.0E-22 T 28-03-2018 CDW54_RS05670 f53d25a66d2dc040ba25bd05916370e2 444 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 173 187 6.0E-51 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CDW54_RS05670 f53d25a66d2dc040ba25bd05916370e2 444 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 141 161 6.0E-51 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CDW54_RS05670 f53d25a66d2dc040ba25bd05916370e2 444 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 402 421 6.0E-51 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CDW54_RS05670 f53d25a66d2dc040ba25bd05916370e2 444 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 205 219 6.0E-51 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CDW54_RS05670 f53d25a66d2dc040ba25bd05916370e2 444 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 239 266 6.0E-51 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CDW54_RS01590 cb53bd367482065708b5adfd077b99de 295 SUPERFAMILY SSF51735 1 162 1.07E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS01590 cb53bd367482065708b5adfd077b99de 295 PIRSF PIRSF000103 1 289 5.3E-69 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CDW54_RS01590 cb53bd367482065708b5adfd077b99de 295 Gene3D G3DSA:3.40.50.720 1 162 1.3E-31 T 28-03-2018 CDW54_RS01590 cb53bd367482065708b5adfd077b99de 295 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 160 6.7E-49 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CDW54_RS01590 cb53bd367482065708b5adfd077b99de 295 Gene3D G3DSA:1.10.1040.10 163 288 2.8E-32 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CDW54_RS01590 cb53bd367482065708b5adfd077b99de 295 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 164 283 2.5E-33 T 28-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CDW54_RS01590 cb53bd367482065708b5adfd077b99de 295 SUPERFAMILY SSF48179 163 284 2.49E-37 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CDW54_RS11355 d3256c38dc2693e6d27ce728527b6c38 222 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 207 7.7E-35 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CDW54_RS11355 d3256c38dc2693e6d27ce728527b6c38 222 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 1 220 3.1E-81 T 28-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 CDW54_RS11355 d3256c38dc2693e6d27ce728527b6c38 222 Gene3D G3DSA:3.40.50.1240 1 222 1.7E-57 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CDW54_RS11355 d3256c38dc2693e6d27ce728527b6c38 222 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 1 222 36.625 T 28-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 CDW54_RS11355 d3256c38dc2693e6d27ce728527b6c38 222 SUPERFAMILY SSF53254 1 214 1.44E-64 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CDW54_RS11355 d3256c38dc2693e6d27ce728527b6c38 222 PIRSF PIRSF000709 2 210 1.1E-8 T 28-03-2018 CDW54_RS11355 d3256c38dc2693e6d27ce728527b6c38 222 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 5 14 - T 28-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CDW54_RS11355 d3256c38dc2693e6d27ce728527b6c38 222 SMART SM00855 2 183 4.2E-23 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CDW54_RS01510 f2a9d57b404df7bb8121321596d903d7 103 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 9 94 7.0E-43 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CDW54_RS01510 f2a9d57b404df7bb8121321596d903d7 103 Pfam PF01985 CRS1 / YhbY (CRM) domain 3 86 8.3E-22 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CDW54_RS01510 f2a9d57b404df7bb8121321596d903d7 103 TIGRFAM TIGR00253 RNA_bind_YhbY: putative RNA-binding protein, YhbY family 3 94 6.4E-32 T 28-03-2018 IPR017924 RNA-binding protein YhbY GO:0003723 CDW54_RS01510 f2a9d57b404df7bb8121321596d903d7 103 SUPERFAMILY SSF75471 1 95 9.16E-30 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CDW54_RS01510 f2a9d57b404df7bb8121321596d903d7 103 SMART SM01103 3 86 4.7E-39 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CDW54_RS01510 f2a9d57b404df7bb8121321596d903d7 103 Gene3D G3DSA:3.30.110.60 2 98 3.2E-27 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CDW54_RS10950 a77cb48bfa4801e16dc99002995a91de 196 Gene3D G3DSA:3.40.50.880 1 180 2.2E-19 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CDW54_RS10950 a77cb48bfa4801e16dc99002995a91de 196 Pfam PF01965 DJ-1/PfpI family 4 163 3.8E-23 T 28-03-2018 IPR002818 DJ-1/PfpI CDW54_RS10950 a77cb48bfa4801e16dc99002995a91de 196 SUPERFAMILY SSF52317 1 166 7.64E-26 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CDW54_RS08010 cc423ee59bac6f4427243ec2cac0f769 279 SUPERFAMILY SSF81345 6 262 2.62E-46 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CDW54_RS08010 cc423ee59bac6f4427243ec2cac0f769 279 Gene3D G3DSA:1.10.3470.10 5 274 7.2E-37 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CDW54_RS08010 cc423ee59bac6f4427243ec2cac0f769 279 Pfam PF00950 ABC 3 transport family 11 266 3.4E-82 T 28-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 CDW54_RS06575 c542502452fff5e11bfcff01e10728fa 505 SMART SM00487 22 219 3.1E-63 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CDW54_RS06575 c542502452fff5e11bfcff01e10728fa 505 SMART SM00490 255 336 1.1E-35 T 28-03-2018 IPR001650 Helicase, C-terminal CDW54_RS06575 c542502452fff5e11bfcff01e10728fa 505 Pfam PF00271 Helicase conserved C-terminal domain 228 336 7.3E-30 T 28-03-2018 IPR001650 Helicase, C-terminal CDW54_RS06575 c542502452fff5e11bfcff01e10728fa 505 SUPERFAMILY SSF52540 72 357 1.11E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS06575 c542502452fff5e11bfcff01e10728fa 505 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 150 158 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site CDW54_RS06575 c542502452fff5e11bfcff01e10728fa 505 Hamap MF_01493 DEAD-box ATP-dependent RNA helicase CshA [cshA]. 3 501 46.015 T 28-03-2018 IPR030880 DEAD-box ATP-dependent RNA helicase CshA GO:0004004|GO:0005524|GO:0010501 CDW54_RS06575 c542502452fff5e11bfcff01e10728fa 505 Pfam PF00270 DEAD/DEAH box helicase 27 192 1.3E-49 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CDW54_RS06575 c542502452fff5e11bfcff01e10728fa 505 Gene3D G3DSA:3.40.50.300 219 500 5.9E-47 T 28-03-2018 CDW54_RS06575 c542502452fff5e11bfcff01e10728fa 505 Gene3D G3DSA:3.40.50.300 4 218 1.2E-60 T 28-03-2018 CDW54_RS02060 88a577abed42082c3627347435cc0795 362 Gene3D G3DSA:3.40.50.2000 178 343 9.2E-30 T 28-03-2018 CDW54_RS02060 88a577abed42082c3627347435cc0795 362 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 3 360 34.092 T 28-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CDW54_RS02060 88a577abed42082c3627347435cc0795 362 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 1 355 5.7E-99 T 28-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CDW54_RS02060 88a577abed42082c3627347435cc0795 362 Gene3D G3DSA:3.40.50.2000 1 177 2.8E-37 T 28-03-2018 CDW54_RS02060 88a577abed42082c3627347435cc0795 362 SUPERFAMILY SSF53756 1 361 1.26E-110 T 28-03-2018 CDW54_RS02060 88a577abed42082c3627347435cc0795 362 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 188 352 2.7E-44 T 28-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CDW54_RS02060 88a577abed42082c3627347435cc0795 362 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 142 1.5E-47 T 28-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CDW54_RS08210 0f9e09832823184cf67b224278313053 324 SUPERFAMILY SSF53271 8 163 5.27E-54 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CDW54_RS08210 0f9e09832823184cf67b224278313053 324 Gene3D G3DSA:3.40.50.2020 160 318 9.8E-34 T 28-03-2018 CDW54_RS08210 0f9e09832823184cf67b224278313053 324 SMART SM01400 10 126 2.6E-74 T 28-03-2018 CDW54_RS08210 0f9e09832823184cf67b224278313053 324 Pfam PF14572 Phosphoribosyl synthetase-associated domain 211 317 4.4E-25 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CDW54_RS08210 0f9e09832823184cf67b224278313053 324 Gene3D G3DSA:3.40.50.2020 8 159 3.6E-64 T 28-03-2018 CDW54_RS08210 0f9e09832823184cf67b224278313053 324 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 134 149 - T 28-03-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 CDW54_RS08210 0f9e09832823184cf67b224278313053 324 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 10 126 6.8E-48 T 28-03-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CDW54_RS08210 0f9e09832823184cf67b224278313053 324 SUPERFAMILY SSF53271 112 308 5.92E-43 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CDW54_RS08210 0f9e09832823184cf67b224278313053 324 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 10 317 44.229 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CDW54_RS08210 0f9e09832823184cf67b224278313053 324 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 11 316 2.9E-104 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CDW54_RS05550 b0c6829daeb69f82b674bbfb85640545 494 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 12 492 84.834 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CDW54_RS05550 b0c6829daeb69f82b674bbfb85640545 494 Pfam PF00571 CBS domain 156 206 2.4E-9 T 28-03-2018 IPR000644 CBS domain CDW54_RS05550 b0c6829daeb69f82b674bbfb85640545 494 Pfam PF00571 CBS domain 100 146 2.6E-6 T 28-03-2018 IPR000644 CBS domain CDW54_RS05550 b0c6829daeb69f82b674bbfb85640545 494 SUPERFAMILY SSF51412 7 94 1.96E-122 T 28-03-2018 CDW54_RS05550 b0c6829daeb69f82b674bbfb85640545 494 SUPERFAMILY SSF51412 222 483 1.96E-122 T 28-03-2018 CDW54_RS05550 b0c6829daeb69f82b674bbfb85640545 494 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 12 460 5.4E-200 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CDW54_RS05550 b0c6829daeb69f82b674bbfb85640545 494 SMART SM00116 163 211 1.7E-9 T 28-03-2018 IPR000644 CBS domain CDW54_RS05550 b0c6829daeb69f82b674bbfb85640545 494 SMART SM00116 100 150 2.1E-7 T 28-03-2018 IPR000644 CBS domain CDW54_RS05550 b0c6829daeb69f82b674bbfb85640545 494 PIRSF PIRSF000130 1 494 8.2E-211 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CDW54_RS05550 b0c6829daeb69f82b674bbfb85640545 494 Gene3D G3DSA:3.20.20.70 2 488 1.3E-111 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDW54_RS05550 b0c6829daeb69f82b674bbfb85640545 494 SMART SM01240 11 479 0.0 T 28-03-2018 CDW54_RS05550 b0c6829daeb69f82b674bbfb85640545 494 SUPERFAMILY SSF54631 68 210 5.05E-31 T 28-03-2018 CDW54_RS05550 b0c6829daeb69f82b674bbfb85640545 494 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 12 479 7.6E-163 T 28-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 CDW54_RS05550 b0c6829daeb69f82b674bbfb85640545 494 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 300 312 - T 28-03-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 CDW54_RS12405 a5ee50d7d86bcd2ca83c0788597a89bb 154 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 92 107 9.8E-16 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CDW54_RS12405 a5ee50d7d86bcd2ca83c0788597a89bb 154 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 47 55 9.8E-16 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CDW54_RS12405 a5ee50d7d86bcd2ca83c0788597a89bb 154 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 126 142 9.8E-16 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CDW54_RS12405 a5ee50d7d86bcd2ca83c0788597a89bb 154 ProSitePatterns PS00855 Signal peptidases II signature. 95 107 - T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CDW54_RS12405 a5ee50d7d86bcd2ca83c0788597a89bb 154 Pfam PF01252 Signal peptidase (SPase) II 10 145 5.1E-40 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CDW54_RS12405 a5ee50d7d86bcd2ca83c0788597a89bb 154 TIGRFAM TIGR00077 lspA: signal peptidase II 3 153 2.8E-37 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CDW54_RS12405 a5ee50d7d86bcd2ca83c0788597a89bb 154 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 1 151 16.613 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CDW54_RS06100 03ec9bc14b1a902eaa6940229f580558 142 Gene3D G3DSA:3.30.70.920 59 142 3.3E-7 T 28-03-2018 CDW54_RS06100 03ec9bc14b1a902eaa6940229f580558 142 SMART SM00344 12 116 1.4E-19 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CDW54_RS06100 03ec9bc14b1a902eaa6940229f580558 142 Gene3D G3DSA:1.10.10.10 11 58 8.0E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS06100 03ec9bc14b1a902eaa6940229f580558 142 SUPERFAMILY SSF46785 13 69 6.04E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS06100 03ec9bc14b1a902eaa6940229f580558 142 SUPERFAMILY SSF54909 71 141 3.65E-5 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CDW54_RS06100 03ec9bc14b1a902eaa6940229f580558 142 Pfam PF13412 Winged helix-turn-helix DNA-binding 14 56 3.1E-13 T 28-03-2018 CDW54_RS06100 03ec9bc14b1a902eaa6940229f580558 142 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 25 36 3.5E-7 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CDW54_RS06100 03ec9bc14b1a902eaa6940229f580558 142 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 9 25 3.5E-7 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CDW54_RS06100 03ec9bc14b1a902eaa6940229f580558 142 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 36 55 3.5E-7 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CDW54_RS07550 6d6082afd50159f9180d1885089ab199 221 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 77 189 1.7E-15 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDW54_RS07550 6d6082afd50159f9180d1885089ab199 221 TIGRFAM TIGR02009 PGMB-YQAB-SF: beta-phosphoglucomutase family hydrolase 2 189 9.5E-61 T 28-03-2018 IPR010976 Beta-phosphoglucomutase hydrolase CDW54_RS07550 6d6082afd50159f9180d1885089ab199 221 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 188 1.2E-22 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS07550 6d6082afd50159f9180d1885089ab199 221 Gene3D G3DSA:3.40.50.1000 78 217 5.2E-22 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS07550 6d6082afd50159f9180d1885089ab199 221 TIGRFAM TIGR01990 bPGM: beta-phosphoglucomutase 2 190 6.6E-80 T 28-03-2018 IPR010972 Beta-phosphoglucomutase GO:0000287|GO:0005975|GO:0008801 KEGG: 00500+5.4.2.6|MetaCyc: PWY-2721|MetaCyc: PWY-2722|MetaCyc: PWY-7459 CDW54_RS07550 6d6082afd50159f9180d1885089ab199 221 SUPERFAMILY SSF56784 1 207 3.25E-47 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS07550 6d6082afd50159f9180d1885089ab199 221 Gene3D G3DSA:1.10.150.240 15 77 4.0E-23 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CDW54_RS05950 9d1c1bcd3f7f9987e233ba5cde644b71 218 SMART SM00322 59 124 2.5E-9 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CDW54_RS05950 9d1c1bcd3f7f9987e233ba5cde644b71 218 Pfam PF07650 KH domain 38 109 1.4E-20 T 28-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS05950 9d1c1bcd3f7f9987e233ba5cde644b71 218 ProSitePatterns PS00548 Ribosomal protein S3 signature. 162 196 - T 28-03-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS05950 9d1c1bcd3f7f9987e233ba5cde644b71 218 SUPERFAMILY SSF54821 106 205 8.24E-37 T 28-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS05950 9d1c1bcd3f7f9987e233ba5cde644b71 218 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 201 3.1E-39 T 28-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS05950 9d1c1bcd3f7f9987e233ba5cde644b71 218 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 208 1.6E-93 T 28-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 CDW54_RS05950 9d1c1bcd3f7f9987e233ba5cde644b71 218 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 205 38.504 T 28-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 CDW54_RS05950 9d1c1bcd3f7f9987e233ba5cde644b71 218 Gene3D G3DSA:3.30.1140.32 107 206 1.4E-35 T 28-03-2018 CDW54_RS05950 9d1c1bcd3f7f9987e233ba5cde644b71 218 SUPERFAMILY SSF54814 2 105 3.92E-37 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CDW54_RS05950 9d1c1bcd3f7f9987e233ba5cde644b71 218 Gene3D G3DSA:3.30.300.20 17 106 1.6E-30 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CDW54_RS04590 c5b8dd522de4c10758e1a9877691310a 570 Gene3D G3DSA:1.20.1560.10 1 314 1.5E-58 T 28-03-2018 CDW54_RS04590 c5b8dd522de4c10758e1a9877691310a 570 SUPERFAMILY SSF52540 324 565 3.74E-80 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS04590 c5b8dd522de4c10758e1a9877691310a 570 Gene3D G3DSA:3.40.50.300 317 570 6.7E-69 T 28-03-2018 CDW54_RS04590 c5b8dd522de4c10758e1a9877691310a 570 SUPERFAMILY SSF90123 4 319 1.96E-60 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CDW54_RS04590 c5b8dd522de4c10758e1a9877691310a 570 SMART SM00382 355 541 7.2E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS04590 c5b8dd522de4c10758e1a9877691310a 570 Pfam PF00664 ABC transporter transmembrane region 15 284 5.8E-33 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CDW54_RS04590 c5b8dd522de4c10758e1a9877691310a 570 Pfam PF00005 ABC transporter 346 495 2.8E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS10840 c8f932b92e9044c5156a85e20806d731 270 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 26 257 4.2E-87 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CDW54_RS10840 c8f932b92e9044c5156a85e20806d731 270 Gene3D G3DSA:3.40.1180.10 12 261 6.3E-95 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CDW54_RS10840 c8f932b92e9044c5156a85e20806d731 270 SUPERFAMILY SSF64005 24 253 1.44E-87 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CDW54_RS10840 c8f932b92e9044c5156a85e20806d731 270 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 26 258 40.304 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CDW54_RS10840 c8f932b92e9044c5156a85e20806d731 270 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 203 220 - T 28-03-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199 CDW54_RS10840 c8f932b92e9044c5156a85e20806d731 270 Pfam PF01255 Putative undecaprenyl diphosphate synthase 33 257 1.1E-83 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CDW54_RS09890 86115725f6ae12cf670acd9ef3976150 300 Hamap MF_00152 Probable endonuclease 4 [nfo]. 1 284 40.377 T 28-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 CDW54_RS09890 86115725f6ae12cf670acd9ef3976150 300 ProSitePatterns PS00731 AP endonucleases family 2 signature 3. 212 228 - T 28-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 CDW54_RS09890 86115725f6ae12cf670acd9ef3976150 300 SMART SM00518 2 284 6.1E-119 T 28-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 CDW54_RS09890 86115725f6ae12cf670acd9ef3976150 300 TIGRFAM TIGR00587 nfo: apurinic endonuclease (APN1) 2 281 3.4E-94 T 28-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 CDW54_RS09890 86115725f6ae12cf670acd9ef3976150 300 Gene3D G3DSA:3.20.20.150 1 297 5.5E-57 T 28-03-2018 CDW54_RS09890 86115725f6ae12cf670acd9ef3976150 300 SUPERFAMILY SSF51658 1 290 7.86E-99 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CDW54_RS09890 86115725f6ae12cf670acd9ef3976150 300 Pfam PF01261 Xylose isomerase-like TIM barrel 20 236 2.2E-36 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CDW54_RS09890 86115725f6ae12cf670acd9ef3976150 300 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 174 181 - T 28-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 CDW54_RS09890 86115725f6ae12cf670acd9ef3976150 300 ProSitePatterns PS00729 AP endonucleases family 2 signature 1. 68 76 - T 28-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 CDW54_RS10640 4a9ab45eca0abb8bb1388c97ede6a70c 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 53 2.4E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDW54_RS10640 4a9ab45eca0abb8bb1388c97ede6a70c 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 5.5E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDW54_RS10640 4a9ab45eca0abb8bb1388c97ede6a70c 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 5.5E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDW54_RS10640 4a9ab45eca0abb8bb1388c97ede6a70c 188 SUPERFAMILY SSF48498 76 179 3.11E-12 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CDW54_RS10640 4a9ab45eca0abb8bb1388c97ede6a70c 188 Pfam PF13305 WHG domain 82 158 1.7E-9 T 28-03-2018 IPR025996 WHG domain CDW54_RS10640 4a9ab45eca0abb8bb1388c97ede6a70c 188 Gene3D G3DSA:1.10.357.10 1 182 5.3E-19 T 28-03-2018 CDW54_RS10640 4a9ab45eca0abb8bb1388c97ede6a70c 188 SUPERFAMILY SSF46689 2 70 5.13E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDW54_RS00745 2c3b9f276466e57e73e6f4e53cdccb30 466 Gene3D G3DSA:1.10.8.60 358 454 9.2E-32 T 28-03-2018 CDW54_RS00745 2c3b9f276466e57e73e6f4e53cdccb30 466 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 358 433 3.7E-8 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CDW54_RS00745 2c3b9f276466e57e73e6f4e53cdccb30 466 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 3 466 41.619 T 28-03-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 CDW54_RS00745 2c3b9f276466e57e73e6f4e53cdccb30 466 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 55 147 5.7E-8 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CDW54_RS00745 2c3b9f276466e57e73e6f4e53cdccb30 466 Gene3D G3DSA:3.40.50.300 3 355 4.3E-48 T 28-03-2018 CDW54_RS00745 2c3b9f276466e57e73e6f4e53cdccb30 466 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 7 466 1.0E-191 T 28-03-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 CDW54_RS00745 2c3b9f276466e57e73e6f4e53cdccb30 466 Pfam PF07724 AAA domain (Cdc48 subfamily) 222 352 9.0E-38 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CDW54_RS00745 2c3b9f276466e57e73e6f4e53cdccb30 466 SMART SM00382 51 359 8.7E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS00745 2c3b9f276466e57e73e6f4e53cdccb30 466 SUPERFAMILY SSF52540 180 464 8.61E-84 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS00745 2c3b9f276466e57e73e6f4e53cdccb30 466 SUPERFAMILY SSF52540 7 141 8.61E-84 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS00745 2c3b9f276466e57e73e6f4e53cdccb30 466 SMART SM01086 358 457 6.9E-26 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CDW54_RS12565 84a3b6ef4a09efb7afa9bc1321fb4068 147 Pfam PF01047 MarR family 33 91 6.2E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDW54_RS12565 84a3b6ef4a09efb7afa9bc1321fb4068 147 Gene3D G3DSA:1.10.10.10 1 133 3.2E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS12565 84a3b6ef4a09efb7afa9bc1321fb4068 147 SUPERFAMILY SSF46785 12 143 3.42E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS12565 84a3b6ef4a09efb7afa9bc1321fb4068 147 SMART SM00347 26 129 1.2E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDW54_RS09160 e9d4ec741acc7abacb8cbe9454d9fe12 329 SMART SM00829 17 323 4.2E-5 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CDW54_RS09160 e9d4ec741acc7abacb8cbe9454d9fe12 329 Gene3D G3DSA:3.90.180.10 6 149 9.9E-31 T 28-03-2018 CDW54_RS09160 e9d4ec741acc7abacb8cbe9454d9fe12 329 SUPERFAMILY SSF50129 16 145 1.17E-36 T 28-03-2018 IPR011032 GroES-like CDW54_RS09160 e9d4ec741acc7abacb8cbe9454d9fe12 329 Pfam PF00107 Zinc-binding dehydrogenase 159 273 6.4E-17 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CDW54_RS09160 e9d4ec741acc7abacb8cbe9454d9fe12 329 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 8 325 9.4E-127 T 28-03-2018 IPR014188 Acrylyl-CoA reductase AcuI CDW54_RS09160 e9d4ec741acc7abacb8cbe9454d9fe12 329 SUPERFAMILY SSF51735 117 290 1.04E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS09160 e9d4ec741acc7abacb8cbe9454d9fe12 329 Gene3D G3DSA:3.40.50.720 150 270 6.3E-20 T 28-03-2018 CDW54_RS01135 1dd521c15dabc7d1ce637f71fbc5fddb 146 Gene3D G3DSA:3.40.50.620 1 146 6.0E-34 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDW54_RS01135 1dd521c15dabc7d1ce637f71fbc5fddb 146 SUPERFAMILY SSF52402 5 146 1.76E-34 T 28-03-2018 CDW54_RS01135 1dd521c15dabc7d1ce637f71fbc5fddb 146 PRINTS PR01438 Universal stress protein signature 106 118 3.5E-18 T 28-03-2018 IPR006015 Universal stress protein A CDW54_RS01135 1dd521c15dabc7d1ce637f71fbc5fddb 146 PRINTS PR01438 Universal stress protein signature 5 23 3.5E-18 T 28-03-2018 IPR006015 Universal stress protein A CDW54_RS01135 1dd521c15dabc7d1ce637f71fbc5fddb 146 PRINTS PR01438 Universal stress protein signature 124 146 3.5E-18 T 28-03-2018 IPR006015 Universal stress protein A CDW54_RS01135 1dd521c15dabc7d1ce637f71fbc5fddb 146 PIRSF PIRSF006276 1 146 1.2E-19 T 28-03-2018 IPR006015 Universal stress protein A CDW54_RS01135 1dd521c15dabc7d1ce637f71fbc5fddb 146 Pfam PF00582 Universal stress protein family 5 146 4.0E-33 T 28-03-2018 IPR006016 UspA GO:0006950 CDW54_RS02480 a6132d29d8dc65bd523866651927fe5a 446 Gene3D G3DSA:3.10.20.70 4 106 1.4E-38 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CDW54_RS02480 a6132d29d8dc65bd523866651927fe5a 446 SUPERFAMILY SSF54368 8 106 7.19E-35 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CDW54_RS02480 a6132d29d8dc65bd523866651927fe5a 446 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 9 443 2.2E-177 T 28-03-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CDW54_RS02480 a6132d29d8dc65bd523866651927fe5a 446 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 236 251 - T 28-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CDW54_RS02480 a6132d29d8dc65bd523866651927fe5a 446 Pfam PF00120 Glutamine synthetase, catalytic domain 108 442 3.4E-140 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CDW54_RS02480 a6132d29d8dc65bd523866651927fe5a 446 Gene3D G3DSA:3.30.590.10 107 446 1.3E-128 T 28-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CDW54_RS02480 a6132d29d8dc65bd523866651927fe5a 446 SUPERFAMILY SSF55931 108 444 8.63E-128 T 28-03-2018 CDW54_RS02480 a6132d29d8dc65bd523866651927fe5a 446 ProSitePatterns PS00180 Glutamine synthetase signature 1. 54 72 - T 28-03-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CDW54_RS02480 a6132d29d8dc65bd523866651927fe5a 446 SMART SM01230 107 356 5.8E-140 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CDW54_RS02480 a6132d29d8dc65bd523866651927fe5a 446 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 19 101 1.6E-32 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CDW54_RS05840 e901fdd5e8969d4875382426cbf2b972 360 Gene3D G3DSA:3.40.50.2300 39 160 3.1E-37 T 28-03-2018 CDW54_RS05840 e901fdd5e8969d4875382426cbf2b972 360 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 45 355 2.2E-66 T 28-03-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 CDW54_RS05840 e901fdd5e8969d4875382426cbf2b972 360 Gene3D G3DSA:3.40.50.2300 161 357 9.0E-44 T 28-03-2018 CDW54_RS05840 e901fdd5e8969d4875382426cbf2b972 360 SUPERFAMILY SSF53822 56 271 4.71E-14 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CDW54_RS06935 701e8bb27de23a7b79db8ff813ae179b 263 Pfam PF08951 Enterocin A Immunity 5 70 2.6E-11 T 28-03-2018 IPR015046 Enterocin A Immunity CDW54_RS06935 701e8bb27de23a7b79db8ff813ae179b 263 SUPERFAMILY SSF55068 93 255 8.89E-66 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CDW54_RS06935 701e8bb27de23a7b79db8ff813ae179b 263 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 95 246 8.8E-55 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CDW54_RS06935 701e8bb27de23a7b79db8ff813ae179b 263 Pfam PF01625 Peptide methionine sulfoxide reductase 97 247 2.3E-57 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CDW54_RS06935 701e8bb27de23a7b79db8ff813ae179b 263 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 94 253 34.607 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CDW54_RS06935 701e8bb27de23a7b79db8ff813ae179b 263 Gene3D G3DSA:3.30.1060.10 93 262 1.1E-61 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CDW54_RS02530 67e0d22b3681ea2603bb019148bc568e 576 SUPERFAMILY SSF90123 4 318 9.94E-71 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CDW54_RS02530 67e0d22b3681ea2603bb019148bc568e 576 Pfam PF00664 ABC transporter transmembrane region 15 280 1.0E-44 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CDW54_RS02530 67e0d22b3681ea2603bb019148bc568e 576 Pfam PF00005 ABC transporter 351 497 7.5E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS02530 67e0d22b3681ea2603bb019148bc568e 576 SMART SM00382 359 545 3.7E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS02530 67e0d22b3681ea2603bb019148bc568e 576 SUPERFAMILY SSF52540 325 569 4.19E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS02530 67e0d22b3681ea2603bb019148bc568e 576 Gene3D G3DSA:1.20.1560.10 1 315 1.4E-69 T 28-03-2018 CDW54_RS02530 67e0d22b3681ea2603bb019148bc568e 576 ProSitePatterns PS00211 ABC transporters family signature. 471 485 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS02530 67e0d22b3681ea2603bb019148bc568e 576 Gene3D G3DSA:3.40.50.300 316 575 3.8E-71 T 28-03-2018 CDW54_RS02085 685301f2e331732cb9204b8083190afb 319 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 2 313 7.1E-126 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CDW54_RS02085 685301f2e331732cb9204b8083190afb 319 SUPERFAMILY SSF81799 117 218 4.45E-36 T 28-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CDW54_RS02085 685301f2e331732cb9204b8083190afb 319 PIRSF PIRSF004486 1 315 1.3E-111 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CDW54_RS02085 685301f2e331732cb9204b8083190afb 319 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 7 314 39.479 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CDW54_RS02085 685301f2e331732cb9204b8083190afb 319 Gene3D G3DSA:3.40.50.150 2 115 0.0021 T 28-03-2018 CDW54_RS02085 685301f2e331732cb9204b8083190afb 319 SUPERFAMILY SSF53335 218 314 2.91E-49 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDW54_RS02085 685301f2e331732cb9204b8083190afb 319 SUPERFAMILY SSF53335 7 116 2.91E-49 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDW54_RS02085 685301f2e331732cb9204b8083190afb 319 Pfam PF01795 MraW methylase family 5 314 1.2E-136 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CDW54_RS02085 685301f2e331732cb9204b8083190afb 319 Gene3D G3DSA:1.10.150.170 116 220 9.9E-39 T 28-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CDW54_RS04895 e234bdf83bfc9fc9a59b4146145a3247 452 SUPERFAMILY SSF53335 145 452 2.46E-67 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDW54_RS04895 e234bdf83bfc9fc9a59b4146145a3247 452 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 233 247 1.1E-29 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CDW54_RS04895 e234bdf83bfc9fc9a59b4146145a3247 452 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 383 399 1.1E-29 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CDW54_RS04895 e234bdf83bfc9fc9a59b4146145a3247 452 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 262 272 1.1E-29 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CDW54_RS04895 e234bdf83bfc9fc9a59b4146145a3247 452 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 333 345 1.1E-29 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CDW54_RS04895 e234bdf83bfc9fc9a59b4146145a3247 452 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 434 451 1.1E-29 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CDW54_RS04895 e234bdf83bfc9fc9a59b4146145a3247 452 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 13 452 1.7E-125 T 28-03-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CDW54_RS04895 e234bdf83bfc9fc9a59b4146145a3247 452 Pfam PF01029 NusB family 11 134 4.3E-29 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CDW54_RS04895 e234bdf83bfc9fc9a59b4146145a3247 452 Gene3D G3DSA:1.10.940.10 7 148 8.1E-29 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CDW54_RS04895 e234bdf83bfc9fc9a59b4146145a3247 452 Gene3D G3DSA:3.40.50.150 242 452 2.1E-59 T 28-03-2018 CDW54_RS04895 e234bdf83bfc9fc9a59b4146145a3247 452 SUPERFAMILY SSF48013 8 136 4.19E-35 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CDW54_RS04895 e234bdf83bfc9fc9a59b4146145a3247 452 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 332 343 - T 28-03-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CDW54_RS04895 e234bdf83bfc9fc9a59b4146145a3247 452 Pfam PF01189 16S rRNA methyltransferase RsmB/F 254 449 6.2E-58 T 28-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CDW54_RS04895 e234bdf83bfc9fc9a59b4146145a3247 452 Gene3D G3DSA:3.30.70.1170 187 241 2.8E-7 T 28-03-2018 CDW54_RS00975 c6c9ff59acd4bde4a75bd1211acaad00 189 Hamap MF_01804 Segregation and condensation protein B [scpB]. 1 181 32.516 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CDW54_RS00975 c6c9ff59acd4bde4a75bd1211acaad00 189 Gene3D G3DSA:1.10.10.10 83 173 4.5E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS00975 c6c9ff59acd4bde4a75bd1211acaad00 189 SUPERFAMILY SSF46785 83 156 3.3E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS00975 c6c9ff59acd4bde4a75bd1211acaad00 189 Pfam PF04079 Segregation and condensation complex subunit ScpB 6 164 5.4E-55 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CDW54_RS00975 c6c9ff59acd4bde4a75bd1211acaad00 189 SUPERFAMILY SSF46785 5 79 4.36E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS00975 c6c9ff59acd4bde4a75bd1211acaad00 189 Gene3D G3DSA:1.10.10.10 2 82 9.9E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS00975 c6c9ff59acd4bde4a75bd1211acaad00 189 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 7 187 6.2E-48 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CDW54_RS00975 c6c9ff59acd4bde4a75bd1211acaad00 189 PIRSF PIRSF019345 1 188 8.5E-52 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CDW54_RS10140 373a645c3b5ba8d202f9a3bd204302f1 254 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 31 97 1.4E-9 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CDW54_RS10140 373a645c3b5ba8d202f9a3bd204302f1 254 SMART SM00967 31 103 8.7E-10 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CDW54_RS10140 373a645c3b5ba8d202f9a3bd204302f1 254 Gene3D G3DSA:3.40.1280.10 108 254 1.4E-43 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CDW54_RS10140 373a645c3b5ba8d202f9a3bd204302f1 254 SUPERFAMILY SSF55315 2 98 6.83E-24 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CDW54_RS10140 373a645c3b5ba8d202f9a3bd204302f1 254 SUPERFAMILY SSF75217 102 252 1.88E-42 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CDW54_RS10140 373a645c3b5ba8d202f9a3bd204302f1 254 Gene3D G3DSA:3.30.1330.30 3 102 3.2E-26 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CDW54_RS10140 373a645c3b5ba8d202f9a3bd204302f1 254 Pfam PF00588 SpoU rRNA Methylase family 112 250 6.9E-37 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CDW54_RS07420 6faea7c1df71552aa50a4f99fd2f5862 86 Pfam PF02583 Metal-sensitive transcriptional repressor 5 83 1.1E-27 T 28-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 CDW54_RS11905 036cb8366b91f1f616f255853db163f9 678 SUPERFAMILY SSF56601 347 674 3.76E-75 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CDW54_RS11905 036cb8366b91f1f616f255853db163f9 678 Pfam PF03717 Penicillin-binding Protein dimerisation domain 169 330 4.0E-26 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CDW54_RS11905 036cb8366b91f1f616f255853db163f9 678 SUPERFAMILY SSF54427 46 159 6.13E-28 T 28-03-2018 IPR032710 NTF2-like domain CDW54_RS11905 036cb8366b91f1f616f255853db163f9 678 Gene3D G3DSA:3.90.1310.10 247 345 2.6E-20 T 28-03-2018 CDW54_RS11905 036cb8366b91f1f616f255853db163f9 678 SUPERFAMILY SSF56519 163 346 2.62E-33 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CDW54_RS11905 036cb8366b91f1f616f255853db163f9 678 Gene3D G3DSA:3.40.710.10 346 677 1.8E-58 T 28-03-2018 CDW54_RS11905 036cb8366b91f1f616f255853db163f9 678 Gene3D G3DSA:3.30.1390.30 191 246 3.3E-17 T 28-03-2018 CDW54_RS11905 036cb8366b91f1f616f255853db163f9 678 Pfam PF00905 Penicillin binding protein transpeptidase domain 364 663 2.4E-72 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CDW54_RS11905 036cb8366b91f1f616f255853db163f9 678 Gene3D G3DSA:3.10.450.100 42 157 1.5E-25 T 28-03-2018 CDW54_RS11905 036cb8366b91f1f616f255853db163f9 678 Pfam PF05223 NTF2-like N-terminal transpeptidase domain 45 162 3.2E-39 T 28-03-2018 IPR007887 NTF2-like N-terminal transpeptidase GO:0046677 CDW54_RS09065 4e33a92ec5453e3a601a86bdb3b077ca 174 SUPERFAMILY SSF55729 7 173 6.62E-30 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDW54_RS09065 4e33a92ec5453e3a601a86bdb3b077ca 174 Pfam PF00583 Acetyltransferase (GNAT) family 45 146 4.3E-18 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CDW54_RS09065 4e33a92ec5453e3a601a86bdb3b077ca 174 Gene3D G3DSA:3.40.630.30 4 174 3.7E-28 T 28-03-2018 CDW54_RS11425 76e583cc7daea47cc02f4da306c97376 278 SMART SM00898 2 117 3.1E-52 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CDW54_RS11425 76e583cc7daea47cc02f4da306c97376 278 Gene3D G3DSA:3.20.190.10 2 132 1.1E-41 T 28-03-2018 CDW54_RS11425 76e583cc7daea47cc02f4da306c97376 278 Pfam PF06827 Zinc finger found in FPG and IleRS 245 272 1.8E-11 T 28-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 CDW54_RS11425 76e583cc7daea47cc02f4da306c97376 278 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 133 222 1.8E-30 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CDW54_RS11425 76e583cc7daea47cc02f4da306c97376 278 SUPERFAMILY SSF57716 221 272 1.28E-17 T 28-03-2018 CDW54_RS11425 76e583cc7daea47cc02f4da306c97376 278 SMART SM01232 133 225 1.0E-42 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CDW54_RS11425 76e583cc7daea47cc02f4da306c97376 278 ProSitePatterns PS01242 Zinc finger FPG-type signature. 248 272 - T 28-03-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 CDW54_RS11425 76e583cc7daea47cc02f4da306c97376 278 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 116 8.1E-36 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CDW54_RS11425 76e583cc7daea47cc02f4da306c97376 278 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 272 4.7E-107 T 28-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 CDW54_RS11425 76e583cc7daea47cc02f4da306c97376 278 Gene3D G3DSA:1.10.8.50 134 278 7.3E-48 T 28-03-2018 CDW54_RS11425 76e583cc7daea47cc02f4da306c97376 278 SUPERFAMILY SSF81624 2 138 4.97E-42 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CDW54_RS11425 76e583cc7daea47cc02f4da306c97376 278 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 273 44.22 T 28-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 CDW54_RS11425 76e583cc7daea47cc02f4da306c97376 278 SUPERFAMILY SSF46946 132 222 1.91E-28 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CDW54_RS05285 1e9937ae98a44d1e486ef6da23a13769 225 Gene3D G3DSA:1.10.150.240 27 80 2.5E-19 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CDW54_RS05285 1e9937ae98a44d1e486ef6da23a13769 225 Gene3D G3DSA:3.40.50.1000 81 215 3.9E-22 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS05285 1e9937ae98a44d1e486ef6da23a13769 225 TIGRFAM TIGR02009 PGMB-YQAB-SF: beta-phosphoglucomutase family hydrolase 3 190 2.3E-58 T 28-03-2018 IPR010976 Beta-phosphoglucomutase hydrolase CDW54_RS05285 1e9937ae98a44d1e486ef6da23a13769 225 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 134 150 5.7E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDW54_RS05285 1e9937ae98a44d1e486ef6da23a13769 225 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 5.7E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDW54_RS05285 1e9937ae98a44d1e486ef6da23a13769 225 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 152 172 5.7E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDW54_RS05285 1e9937ae98a44d1e486ef6da23a13769 225 TIGRFAM TIGR01990 bPGM: beta-phosphoglucomutase 3 191 1.0E-69 T 28-03-2018 IPR010972 Beta-phosphoglucomutase GO:0000287|GO:0005975|GO:0008801 KEGG: 00500+5.4.2.6|MetaCyc: PWY-2721|MetaCyc: PWY-2722|MetaCyc: PWY-7459 CDW54_RS05285 1e9937ae98a44d1e486ef6da23a13769 225 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 55 189 3.4E-17 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDW54_RS05285 1e9937ae98a44d1e486ef6da23a13769 225 SUPERFAMILY SSF56784 2 207 5.7E-48 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS05285 1e9937ae98a44d1e486ef6da23a13769 225 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 189 2.3E-29 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS05285 1e9937ae98a44d1e486ef6da23a13769 225 Gene3D G3DSA:3.40.50.1000 1 26 0.0064 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS01635 b9083b654e0706ea60c449fa43f7cf70 526 Gene3D G3DSA:2.40.30.10 278 392 1.3E-22 T 28-03-2018 CDW54_RS01635 b9083b654e0706ea60c449fa43f7cf70 526 SUPERFAMILY SSF54980 395 466 4.68E-16 T 28-03-2018 IPR035647 EF-G domain III/V-like CDW54_RS01635 b9083b654e0706ea60c449fa43f7cf70 526 Pfam PF00009 Elongation factor Tu GTP binding domain 12 277 8.0E-52 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDW54_RS01635 b9083b654e0706ea60c449fa43f7cf70 526 Pfam PF03144 Elongation factor Tu domain 2 315 380 5.5E-13 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CDW54_RS01635 b9083b654e0706ea60c449fa43f7cf70 526 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 4 526 49.098 T 28-03-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 CDW54_RS01635 b9083b654e0706ea60c449fa43f7cf70 526 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 7 524 7.3E-197 T 28-03-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 CDW54_RS01635 b9083b654e0706ea60c449fa43f7cf70 526 Gene3D G3DSA:3.40.50.300 6 277 2.3E-44 T 28-03-2018 CDW54_RS01635 b9083b654e0706ea60c449fa43f7cf70 526 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 58 73 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CDW54_RS01635 b9083b654e0706ea60c449fa43f7cf70 526 Pfam PF16658 Class II release factor RF3, C-terminal domain 389 513 3.8E-42 T 28-03-2018 IPR032090 Peptide chain release factor 3, C-terminal CDW54_RS01635 b9083b654e0706ea60c449fa43f7cf70 526 Gene3D G3DSA:3.30.70.870 395 467 2.9E-11 T 28-03-2018 CDW54_RS01635 b9083b654e0706ea60c449fa43f7cf70 526 PRINTS PR00315 GTP-binding elongation factor signature 15 28 3.9E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDW54_RS01635 b9083b654e0706ea60c449fa43f7cf70 526 PRINTS PR00315 GTP-binding elongation factor signature 85 95 3.9E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDW54_RS01635 b9083b654e0706ea60c449fa43f7cf70 526 PRINTS PR00315 GTP-binding elongation factor signature 137 146 3.9E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDW54_RS01635 b9083b654e0706ea60c449fa43f7cf70 526 PRINTS PR00315 GTP-binding elongation factor signature 101 112 3.9E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDW54_RS01635 b9083b654e0706ea60c449fa43f7cf70 526 PRINTS PR00315 GTP-binding elongation factor signature 65 73 3.9E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDW54_RS01635 b9083b654e0706ea60c449fa43f7cf70 526 SUPERFAMILY SSF50447 261 389 6.19E-30 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CDW54_RS01635 b9083b654e0706ea60c449fa43f7cf70 526 SUPERFAMILY SSF52540 10 277 9.38E-87 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS01635 b9083b654e0706ea60c449fa43f7cf70 526 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 16 164 4.9E-22 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CDW54_RS09450 2ae6a2ecefd4bb7d10e572f2d97b3afc 328 Pfam PF01992 ATP synthase (C/AC39) subunit 6 321 4.7E-49 T 28-03-2018 IPR002843 ATPase, V0 complex, c/d subunit Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CDW54_RS09450 2ae6a2ecefd4bb7d10e572f2d97b3afc 328 SUPERFAMILY SSF103486 3 324 1.44E-79 T 28-03-2018 IPR002843 ATPase, V0 complex, c/d subunit Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CDW54_RS09450 2ae6a2ecefd4bb7d10e572f2d97b3afc 328 Gene3D G3DSA:1.20.1690.10 177 275 6.1E-9 T 28-03-2018 IPR035067 V-type ATPase subunit c domain Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CDW54_RS09450 2ae6a2ecefd4bb7d10e572f2d97b3afc 328 Gene3D G3DSA:1.20.1690.10 2 69 0.018 T 28-03-2018 IPR035067 V-type ATPase subunit c domain Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CDW54_RS09450 2ae6a2ecefd4bb7d10e572f2d97b3afc 328 Gene3D G3DSA:1.20.1690.10 76 170 9.5E-13 T 28-03-2018 IPR035067 V-type ATPase subunit c domain Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CDW54_RS06335 894663b76debd9569ab9a62adc22a2fa 265 Pfam PF01226 Formate/nitrite transporter 8 255 8.0E-50 T 28-03-2018 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 CDW54_RS06335 894663b76debd9569ab9a62adc22a2fa 265 Gene3D G3DSA:1.20.1080.10 5 264 1.3E-55 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CDW54_RS06570 66f8050546209e1b7d861a03c89b54bb 450 Pfam PF08245 Mur ligase middle domain 105 284 3.7E-43 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CDW54_RS06570 66f8050546209e1b7d861a03c89b54bb 450 SUPERFAMILY SSF63418 5 96 6.54E-21 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CDW54_RS06570 66f8050546209e1b7d861a03c89b54bb 450 Gene3D G3DSA:3.40.1390.10 1 89 3.3E-24 T 28-03-2018 CDW54_RS06570 66f8050546209e1b7d861a03c89b54bb 450 Pfam PF02875 Mur ligase family, glutamate ligase domain 308 376 2.9E-10 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CDW54_RS06570 66f8050546209e1b7d861a03c89b54bb 450 Gene3D G3DSA:3.40.1190.10 90 302 1.1E-53 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CDW54_RS06570 66f8050546209e1b7d861a03c89b54bb 450 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 27 446 8.0E-123 T 28-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDW54_RS06570 66f8050546209e1b7d861a03c89b54bb 450 Gene3D G3DSA:3.90.190.20 305 450 4.8E-36 T 28-03-2018 CDW54_RS06570 66f8050546209e1b7d861a03c89b54bb 450 SUPERFAMILY SSF53623 101 303 1.26E-48 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CDW54_RS06570 66f8050546209e1b7d861a03c89b54bb 450 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 3 447 32.844 T 28-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDW54_RS06570 66f8050546209e1b7d861a03c89b54bb 450 Pfam PF01225 Mur ligase family, catalytic domain 21 93 2.4E-8 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CDW54_RS06570 66f8050546209e1b7d861a03c89b54bb 450 SUPERFAMILY SSF53244 307 446 2.01E-33 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CDW54_RS00345 7c5aa7b0d6428faf262322f8ca02f18d 401 Gene3D G3DSA:1.10.3470.10 29 397 2.0E-25 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CDW54_RS00345 7c5aa7b0d6428faf262322f8ca02f18d 401 Pfam PF02653 Branched-chain amino acid transport system / permease component 54 389 1.7E-39 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CDW54_RS07300 382948ca5b2fc65434dc9c7bd960d2bf 165 SUPERFAMILY SSF55729 1 154 3.27E-31 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDW54_RS07300 382948ca5b2fc65434dc9c7bd960d2bf 165 Pfam PF00583 Acetyltransferase (GNAT) family 47 140 4.2E-16 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CDW54_RS07300 382948ca5b2fc65434dc9c7bd960d2bf 165 Gene3D G3DSA:3.40.630.30 3 163 7.5E-30 T 28-03-2018 CDW54_RS03660 ae9394823bcfdf46f39e62c93f7c99ee 269 Gene3D G3DSA:3.60.15.10 1 267 2.2E-34 T 28-03-2018 IPR001279 Metallo-beta-lactamase CDW54_RS03660 ae9394823bcfdf46f39e62c93f7c99ee 269 SUPERFAMILY SSF56281 13 244 8.52E-43 T 28-03-2018 IPR001279 Metallo-beta-lactamase CDW54_RS03660 ae9394823bcfdf46f39e62c93f7c99ee 269 SMART SM00849 18 196 2.3E-11 T 28-03-2018 IPR001279 Metallo-beta-lactamase CDW54_RS03660 ae9394823bcfdf46f39e62c93f7c99ee 269 Pfam PF00753 Metallo-beta-lactamase superfamily 17 223 1.6E-18 T 28-03-2018 IPR001279 Metallo-beta-lactamase CDW54_RS10700 f3260b3031c2b6f89adc042db83292b5 180 SUPERFAMILY SSF100950 5 178 1.35E-41 T 28-03-2018 CDW54_RS10700 f3260b3031c2b6f89adc042db83292b5 180 PIRSF PIRSF006806 3 180 1.3E-38 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CDW54_RS10700 f3260b3031c2b6f89adc042db83292b5 180 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 5 177 3.2E-30 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CDW54_RS10700 f3260b3031c2b6f89adc042db83292b5 180 Gene3D G3DSA:3.40.50.10420 1 179 4.6E-43 T 28-03-2018 CDW54_RS10700 f3260b3031c2b6f89adc042db83292b5 180 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 5 179 3.2E-44 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CDW54_RS01835 5bf90cd0f846bf614b618ab851e925d7 712 SUPERFAMILY SSF53448 178 390 2.72E-53 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDW54_RS01835 5bf90cd0f846bf614b618ab851e925d7 712 SUPERFAMILY SSF53448 436 689 1.03E-45 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDW54_RS01835 5bf90cd0f846bf614b618ab851e925d7 712 Gene3D G3DSA:3.90.550.10 431 696 1.5E-39 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDW54_RS01835 5bf90cd0f846bf614b618ab851e925d7 712 Gene3D G3DSA:3.90.550.10 148 413 4.2E-48 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDW54_RS01835 5bf90cd0f846bf614b618ab851e925d7 712 Pfam PF00535 Glycosyl transferase family 2 439 572 4.9E-19 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CDW54_RS01835 5bf90cd0f846bf614b618ab851e925d7 712 Pfam PF00535 Glycosyl transferase family 2 181 296 2.5E-24 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CDW54_RS09910 49c381e7abe860d0bdbdc48baeab6d53 583 SUPERFAMILY SSF52540 330 573 1.81E-84 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS09910 49c381e7abe860d0bdbdc48baeab6d53 583 ProSitePatterns PS00211 ABC transporters family signature. 474 488 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS09910 49c381e7abe860d0bdbdc48baeab6d53 583 SUPERFAMILY SSF90123 5 317 4.71E-75 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CDW54_RS09910 49c381e7abe860d0bdbdc48baeab6d53 583 Gene3D G3DSA:3.40.50.300 324 578 1.1E-68 T 28-03-2018 CDW54_RS09910 49c381e7abe860d0bdbdc48baeab6d53 583 Pfam PF00005 ABC transporter 353 501 4.8E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS09910 49c381e7abe860d0bdbdc48baeab6d53 583 SMART SM00382 362 548 2.0E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS09910 49c381e7abe860d0bdbdc48baeab6d53 583 Gene3D G3DSA:1.20.1560.10 1 323 4.7E-66 T 28-03-2018 CDW54_RS09910 49c381e7abe860d0bdbdc48baeab6d53 583 Pfam PF00664 ABC transporter transmembrane region 19 291 4.4E-48 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CDW54_RS01095 cf1776c5589baa05c6a7ff970a39d972 483 SUPERFAMILY SSF56024 264 468 9.87E-46 T 28-03-2018 CDW54_RS01095 cf1776c5589baa05c6a7ff970a39d972 483 Gene3D G3DSA:3.30.870.10 82 278 3.7E-29 T 28-03-2018 CDW54_RS01095 cf1776c5589baa05c6a7ff970a39d972 483 SUPERFAMILY SSF56024 92 312 3.45E-47 T 28-03-2018 CDW54_RS01095 cf1776c5589baa05c6a7ff970a39d972 483 Hamap MF_01916 Cardiolipin synthase. 7 483 39.14 T 28-03-2018 IPR030874 Cardiolipin synthase, Firmicutes-type GO:0008808|GO:0032049 CDW54_RS01095 cf1776c5589baa05c6a7ff970a39d972 483 SMART SM00155 396 423 5.2E-4 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CDW54_RS01095 cf1776c5589baa05c6a7ff970a39d972 483 SMART SM00155 212 239 0.0031 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CDW54_RS01095 cf1776c5589baa05c6a7ff970a39d972 483 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 2 483 5.6E-148 T 28-03-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 CDW54_RS01095 cf1776c5589baa05c6a7ff970a39d972 483 Pfam PF13091 PLD-like domain 324 450 6.8E-29 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CDW54_RS01095 cf1776c5589baa05c6a7ff970a39d972 483 Pfam PF13091 PLD-like domain 129 242 4.1E-15 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CDW54_RS01095 cf1776c5589baa05c6a7ff970a39d972 483 Pfam PF13396 Phospholipase_D-nuclease N-terminal 14 54 6.1E-9 T 28-03-2018 IPR027379 Cardiolipin synthase N-terminal CDW54_RS01095 cf1776c5589baa05c6a7ff970a39d972 483 Gene3D G3DSA:3.30.870.10 309 477 2.8E-29 T 28-03-2018 CDW54_RS09410 f2f81c10ec713512ef25c855a1210a2b 632 SUPERFAMILY SSF56300 371 408 5.32E-12 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CDW54_RS09410 f2f81c10ec713512ef25c855a1210a2b 632 SUPERFAMILY SSF56300 263 270 5.32E-12 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CDW54_RS09410 f2f81c10ec713512ef25c855a1210a2b 632 SUPERFAMILY SSF56300 442 552 5.32E-12 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CDW54_RS09410 f2f81c10ec713512ef25c855a1210a2b 632 SUPERFAMILY SSF56300 181 228 5.32E-12 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CDW54_RS09410 f2f81c10ec713512ef25c855a1210a2b 632 Hamap MF_01854 Fructose-1,6-bisphosphatase class 3 [fbp]. 1 632 34.026 T 28-03-2018 IPR009164 Fructose-1,6-bisphosphatase class 3 GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CDW54_RS09410 f2f81c10ec713512ef25c855a1210a2b 632 Gene3D G3DSA:3.60.21.10 16 559 1.9E-41 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CDW54_RS09410 f2f81c10ec713512ef25c855a1210a2b 632 Pfam PF06874 Firmicute fructose-1,6-bisphosphatase 3 629 1.0E-249 T 28-03-2018 IPR009164 Fructose-1,6-bisphosphatase class 3 GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CDW54_RS05380 7ad42bbb42a848f7df393c687c7a2fbe 322 SUPERFAMILY SSF55681 67 257 1.66E-45 T 28-03-2018 CDW54_RS05380 7ad42bbb42a848f7df393c687c7a2fbe 322 Pfam PF03099 Biotin/lipoate A/B protein ligase family 106 211 8.6E-12 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CDW54_RS05380 7ad42bbb42a848f7df393c687c7a2fbe 322 Gene3D G3DSA:2.30.30.100 272 318 2.0E-9 T 28-03-2018 CDW54_RS05380 7ad42bbb42a848f7df393c687c7a2fbe 322 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 87 316 4.3E-38 T 28-03-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 CDW54_RS05380 7ad42bbb42a848f7df393c687c7a2fbe 322 Gene3D G3DSA:1.10.10.10 2 58 3.6E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS05380 7ad42bbb42a848f7df393c687c7a2fbe 322 Pfam PF08279 HTH domain 6 56 4.0E-14 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CDW54_RS05380 7ad42bbb42a848f7df393c687c7a2fbe 322 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 6 317 29.02 T 28-03-2018 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 CDW54_RS05380 7ad42bbb42a848f7df393c687c7a2fbe 322 Gene3D G3DSA:3.30.930.10 61 268 3.6E-48 T 28-03-2018 CDW54_RS05380 7ad42bbb42a848f7df393c687c7a2fbe 322 SUPERFAMILY SSF50037 272 316 5.95E-6 T 28-03-2018 IPR008988 Transcriptional repressor, C-terminal CDW54_RS05380 7ad42bbb42a848f7df393c687c7a2fbe 322 Pfam PF02237 Biotin protein ligase C terminal domain 272 316 2.8E-5 T 28-03-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 CDW54_RS05380 7ad42bbb42a848f7df393c687c7a2fbe 322 SUPERFAMILY SSF46785 5 58 2.6E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS06315 2426fc20443d7e8f3d78d4e934d68abc 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 1.1E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS06315 2426fc20443d7e8f3d78d4e934d68abc 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.1E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS06315 2426fc20443d7e8f3d78d4e934d68abc 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 1.1E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS06315 2426fc20443d7e8f3d78d4e934d68abc 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.1E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS06315 2426fc20443d7e8f3d78d4e934d68abc 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 1.1E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS06315 2426fc20443d7e8f3d78d4e934d68abc 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 1.1E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS06315 2426fc20443d7e8f3d78d4e934d68abc 253 Gene3D G3DSA:3.40.50.720 1 251 6.6E-65 T 28-03-2018 CDW54_RS06315 2426fc20443d7e8f3d78d4e934d68abc 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CDW54_RS06315 2426fc20443d7e8f3d78d4e934d68abc 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 250 2.8E-59 T 28-03-2018 CDW54_RS06315 2426fc20443d7e8f3d78d4e934d68abc 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 6.2E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS06315 2426fc20443d7e8f3d78d4e934d68abc 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 6.2E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS06315 2426fc20443d7e8f3d78d4e934d68abc 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 6.2E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS06315 2426fc20443d7e8f3d78d4e934d68abc 253 SUPERFAMILY SSF51735 11 252 6.28E-72 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS02185 3ab9b97173479f189b3340b0aeec7439 163 SUPERFAMILY SSF52728 1 160 4.71E-54 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 CDW54_RS02185 3ab9b97173479f189b3340b0aeec7439 163 TIGRFAM TIGR00854 pts-sorbose: PTS system, mannose/fructose/sorbose family, IIB component 3 150 2.7E-53 T 28-03-2018 IPR018455 Phosphotransferase system, sorbose subfamily IIB component, subgroup GO:0005737|GO:0008982|GO:0009401 CDW54_RS02185 3ab9b97173479f189b3340b0aeec7439 163 Pfam PF03830 PTS system sorbose subfamily IIB component 3 150 2.7E-51 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 CDW54_RS02185 3ab9b97173479f189b3340b0aeec7439 163 Gene3D G3DSA:3.40.35.10 2 158 5.6E-55 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 CDW54_RS12585 a06486eba0ca828c8e96b86a402f8cd8 308 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 294 4.0E-68 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CDW54_RS12585 a06486eba0ca828c8e96b86a402f8cd8 308 Gene3D G3DSA:3.40.50.1100 42 139 4.7E-36 T 28-03-2018 CDW54_RS12585 a06486eba0ca828c8e96b86a402f8cd8 308 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 34 52 - T 28-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 CDW54_RS12585 a06486eba0ca828c8e96b86a402f8cd8 308 SUPERFAMILY SSF53686 4 306 3.01E-100 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CDW54_RS12585 a06486eba0ca828c8e96b86a402f8cd8 308 Gene3D G3DSA:3.40.50.1100 140 308 1.9E-55 T 28-03-2018 CDW54_RS12585 a06486eba0ca828c8e96b86a402f8cd8 308 TIGRFAM TIGR01139 cysK: cysteine synthase A 9 305 6.4E-132 T 28-03-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CDW54_RS12585 a06486eba0ca828c8e96b86a402f8cd8 308 TIGRFAM TIGR01136 cysKM: cysteine synthase 9 305 5.9E-126 T 28-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CDW54_RS00720 badc618878a21921f3b0201af80f8ffe 681 Gene3D G3DSA:3.30.565.10 21 225 8.1E-74 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS00720 badc618878a21921f3b0201af80f8ffe 681 ProSitePatterns PS00177 DNA topoisomerase II signature. 430 438 - T 28-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDW54_RS00720 badc618878a21921f3b0201af80f8ffe 681 PRINTS PR00418 DNA topoisomerase II family signature 73 86 3.6E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDW54_RS00720 badc618878a21921f3b0201af80f8ffe 681 PRINTS PR00418 DNA topoisomerase II family signature 532 544 3.6E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDW54_RS00720 badc618878a21921f3b0201af80f8ffe 681 PRINTS PR00418 DNA topoisomerase II family signature 494 510 3.6E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDW54_RS00720 badc618878a21921f3b0201af80f8ffe 681 PRINTS PR00418 DNA topoisomerase II family signature 38 53 3.6E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDW54_RS00720 badc618878a21921f3b0201af80f8ffe 681 PRINTS PR00418 DNA topoisomerase II family signature 512 529 3.6E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDW54_RS00720 badc618878a21921f3b0201af80f8ffe 681 PRINTS PR00418 DNA topoisomerase II family signature 272 285 3.6E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDW54_RS00720 badc618878a21921f3b0201af80f8ffe 681 PRINTS PR00418 DNA topoisomerase II family signature 115 129 3.6E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDW54_RS00720 badc618878a21921f3b0201af80f8ffe 681 PRINTS PR00418 DNA topoisomerase II family signature 428 442 3.6E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDW54_RS00720 badc618878a21921f3b0201af80f8ffe 681 PRINTS PR00418 DNA topoisomerase II family signature 576 592 3.6E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDW54_RS00720 badc618878a21921f3b0201af80f8ffe 681 SMART SM00433 38 637 0.0 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDW54_RS00720 badc618878a21921f3b0201af80f8ffe 681 Pfam PF01751 Toprim domain 427 536 1.0E-17 T 28-03-2018 IPR006171 TOPRIM domain CDW54_RS00720 badc618878a21921f3b0201af80f8ffe 681 SUPERFAMILY SSF56719 402 642 2.3E-86 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CDW54_RS00720 badc618878a21921f3b0201af80f8ffe 681 Pfam PF00204 DNA gyrase B 226 396 4.5E-57 T 28-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDW54_RS00720 badc618878a21921f3b0201af80f8ffe 681 PRINTS PR01159 DNA gyrase subunit B signature 184 199 5.8E-57 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CDW54_RS00720 badc618878a21921f3b0201af80f8ffe 681 PRINTS PR01159 DNA gyrase subunit B signature 316 332 5.8E-57 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CDW54_RS00720 badc618878a21921f3b0201af80f8ffe 681 PRINTS PR01159 DNA gyrase subunit B signature 199 212 5.8E-57 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CDW54_RS00720 badc618878a21921f3b0201af80f8ffe 681 PRINTS PR01159 DNA gyrase subunit B signature 597 609 5.8E-57 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CDW54_RS00720 badc618878a21921f3b0201af80f8ffe 681 PRINTS PR01159 DNA gyrase subunit B signature 246 264 5.8E-57 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CDW54_RS00720 badc618878a21921f3b0201af80f8ffe 681 PRINTS PR01159 DNA gyrase subunit B signature 380 400 5.8E-57 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CDW54_RS00720 badc618878a21921f3b0201af80f8ffe 681 PRINTS PR01159 DNA gyrase subunit B signature 478 487 5.8E-57 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CDW54_RS00720 badc618878a21921f3b0201af80f8ffe 681 PRINTS PR01159 DNA gyrase subunit B signature 366 380 5.8E-57 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CDW54_RS00720 badc618878a21921f3b0201af80f8ffe 681 PRINTS PR01159 DNA gyrase subunit B signature 613 629 5.8E-57 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CDW54_RS00720 badc618878a21921f3b0201af80f8ffe 681 PRINTS PR01159 DNA gyrase subunit B signature 9 19 5.8E-57 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CDW54_RS00720 badc618878a21921f3b0201af80f8ffe 681 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 34 178 2.9E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS00720 badc618878a21921f3b0201af80f8ffe 681 TIGRFAM TIGR01058 parE_Gpos: DNA topoisomerase IV, B subunit 6 644 0.0 T 28-03-2018 IPR005740 DNA topoisomerase 4 subunit B, Firmicutes/Mollicutes GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CDW54_RS00720 badc618878a21921f3b0201af80f8ffe 681 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 572 633 2.5E-29 T 28-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 CDW54_RS00720 badc618878a21921f3b0201af80f8ffe 681 SMART SM00387 34 179 2.8E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS00720 badc618878a21921f3b0201af80f8ffe 681 Gene3D G3DSA:3.30.230.10 226 398 1.5E-55 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CDW54_RS00720 badc618878a21921f3b0201af80f8ffe 681 Gene3D G3DSA:3.40.50.670 409 640 8.0E-95 T 28-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDW54_RS00720 badc618878a21921f3b0201af80f8ffe 681 Hamap MF_00939 DNA topoisomerase 4 subunit B [parE]. 7 642 49.224 T 28-03-2018 IPR005740 DNA topoisomerase 4 subunit B, Firmicutes/Mollicutes GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CDW54_RS00720 badc618878a21921f3b0201af80f8ffe 681 SUPERFAMILY SSF55874 8 216 1.44E-67 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS00720 badc618878a21921f3b0201af80f8ffe 681 SUPERFAMILY SSF54211 226 396 5.31E-53 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CDW54_RS09200 6076c3ae1171eb7801f616741c25b7ce 537 Gene3D G3DSA:3.40.50.720 134 313 2.6E-36 T 28-03-2018 CDW54_RS09200 6076c3ae1171eb7801f616741c25b7ce 537 SUPERFAMILY SSF55424 323 448 1.2E-28 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CDW54_RS09200 6076c3ae1171eb7801f616741c25b7ce 537 Gene3D G3DSA:3.30.390.30 327 454 2.3E-22 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CDW54_RS09200 6076c3ae1171eb7801f616741c25b7ce 537 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 1 292 2.0E-66 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS09200 6076c3ae1171eb7801f616741c25b7ce 537 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 332 431 6.4E-13 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CDW54_RS09200 6076c3ae1171eb7801f616741c25b7ce 537 Gene3D G3DSA:3.50.50.60 1 133 3.5E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS09200 6076c3ae1171eb7801f616741c25b7ce 537 SUPERFAMILY SSF51905 1 315 8.03E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS09200 6076c3ae1171eb7801f616741c25b7ce 537 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 235 251 6.7E-26 T 28-03-2018 CDW54_RS09200 6076c3ae1171eb7801f616741c25b7ce 537 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 6.7E-26 T 28-03-2018 CDW54_RS09200 6076c3ae1171eb7801f616741c25b7ce 537 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 105 123 6.7E-26 T 28-03-2018 CDW54_RS09200 6076c3ae1171eb7801f616741c25b7ce 537 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 284 6.7E-26 T 28-03-2018 CDW54_RS09200 6076c3ae1171eb7801f616741c25b7ce 537 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 153 171 6.7E-26 T 28-03-2018 CDW54_RS09200 6076c3ae1171eb7801f616741c25b7ce 537 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 153 178 4.8E-16 T 28-03-2018 CDW54_RS09200 6076c3ae1171eb7801f616741c25b7ce 537 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 277 284 4.8E-16 T 28-03-2018 CDW54_RS09200 6076c3ae1171eb7801f616741c25b7ce 537 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 236 250 4.8E-16 T 28-03-2018 CDW54_RS09200 6076c3ae1171eb7801f616741c25b7ce 537 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 4.8E-16 T 28-03-2018 CDW54_RS09200 6076c3ae1171eb7801f616741c25b7ce 537 SUPERFAMILY SSF52821 452 532 2.7E-10 T 28-03-2018 IPR001763 Rhodanese-like domain CDW54_RS09200 6076c3ae1171eb7801f616741c25b7ce 537 Gene3D G3DSA:3.40.250.10 455 537 4.2E-8 T 28-03-2018 IPR001763 Rhodanese-like domain CDW54_RS08990 7dfd0d3e3ca94fbf991a2ac17e05b8b0 214 ProSitePatterns PS01334 Pyrrolidone-carboxylate peptidase cysteine active site. 128 142 - T 28-03-2018 IPR033694 Pyroglutamyl peptidase I, Cys active site CDW54_RS08990 7dfd0d3e3ca94fbf991a2ac17e05b8b0 214 SUPERFAMILY SSF53182 1 212 4.84E-72 T 28-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like CDW54_RS08990 7dfd0d3e3ca94fbf991a2ac17e05b8b0 214 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 78 98 8.5E-48 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CDW54_RS08990 7dfd0d3e3ca94fbf991a2ac17e05b8b0 214 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 160 172 8.5E-48 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CDW54_RS08990 7dfd0d3e3ca94fbf991a2ac17e05b8b0 214 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 3 26 8.5E-48 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CDW54_RS08990 7dfd0d3e3ca94fbf991a2ac17e05b8b0 214 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 60 72 8.5E-48 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CDW54_RS08990 7dfd0d3e3ca94fbf991a2ac17e05b8b0 214 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 130 146 8.5E-48 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CDW54_RS08990 7dfd0d3e3ca94fbf991a2ac17e05b8b0 214 ProSitePatterns PS01333 Pyrrolidone-carboxylate peptidase glutamic acid active site. 67 83 - T 28-03-2018 IPR033693 Pyroglutamyl peptidase I, Glu active site CDW54_RS08990 7dfd0d3e3ca94fbf991a2ac17e05b8b0 214 PIRSF PIRSF015592 1 212 1.2E-83 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CDW54_RS08990 7dfd0d3e3ca94fbf991a2ac17e05b8b0 214 Hamap MF_00417 Pyrrolidone-carboxylate peptidase [pcp]. 1 200 39.521 T 28-03-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 CDW54_RS08990 7dfd0d3e3ca94fbf991a2ac17e05b8b0 214 TIGRFAM TIGR00504 pyro_pdase: pyroglutamyl-peptidase I 2 212 7.8E-81 T 28-03-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 CDW54_RS08990 7dfd0d3e3ca94fbf991a2ac17e05b8b0 214 Pfam PF01470 Pyroglutamyl peptidase 1 202 2.0E-86 T 28-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like CDW54_RS08990 7dfd0d3e3ca94fbf991a2ac17e05b8b0 214 Gene3D G3DSA:3.40.630.20 1 214 2.3E-67 T 28-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like CDW54_RS02565 db5e90cbfc6103fcb2427be7d6c37076 437 Pfam PF08245 Mur ligase middle domain 44 271 2.9E-15 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CDW54_RS02565 db5e90cbfc6103fcb2427be7d6c37076 437 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 42 65 - T 28-03-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 CDW54_RS02565 db5e90cbfc6103fcb2427be7d6c37076 437 Gene3D G3DSA:3.40.1190.10 1 299 4.7E-81 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CDW54_RS02565 db5e90cbfc6103fcb2427be7d6c37076 437 SUPERFAMILY SSF53244 298 428 9.89E-25 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CDW54_RS02565 db5e90cbfc6103fcb2427be7d6c37076 437 PIRSF PIRSF001563 1 432 6.4E-146 T 28-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 CDW54_RS02565 db5e90cbfc6103fcb2427be7d6c37076 437 Pfam PF02875 Mur ligase family, glutamate ligase domain 298 369 1.6E-7 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CDW54_RS02565 db5e90cbfc6103fcb2427be7d6c37076 437 SUPERFAMILY SSF53623 1 298 8.24E-94 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CDW54_RS02565 db5e90cbfc6103fcb2427be7d6c37076 437 TIGRFAM TIGR01499 folC: bifunctional protein FolC 22 427 6.1E-132 T 28-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 CDW54_RS02565 db5e90cbfc6103fcb2427be7d6c37076 437 Gene3D G3DSA:3.90.190.20 300 431 1.2E-21 T 28-03-2018 CDW54_RS08135 d5c71ae0337162529601ad57a5af8ac7 297 TIGRFAM TIGR01076 sortase_fam: sortase 116 249 2.1E-39 T 28-03-2018 IPR005754 Sortase family CDW54_RS08135 d5c71ae0337162529601ad57a5af8ac7 297 Gene3D G3DSA:2.40.260.10 45 261 1.2E-41 T 28-03-2018 IPR023365 Sortase domain CDW54_RS08135 d5c71ae0337162529601ad57a5af8ac7 297 Pfam PF04203 Sortase family 118 243 2.4E-21 T 28-03-2018 IPR005754 Sortase family CDW54_RS08135 d5c71ae0337162529601ad57a5af8ac7 297 SUPERFAMILY SSF63817 107 246 6.28E-39 T 28-03-2018 IPR023365 Sortase domain CDW54_RS05320 fc0b9efcbff9e2fb5d64446e144a31f2 289 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 279 1.4E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS05320 fc0b9efcbff9e2fb5d64446e144a31f2 289 SUPERFAMILY SSF161098 56 281 1.14E-56 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS05320 fc0b9efcbff9e2fb5d64446e144a31f2 289 Gene3D G3DSA:1.10.3720.10 13 285 7.1E-50 T 28-03-2018 CDW54_RS12350 e4dba5c91327a35813290e8cab47b2a2 209 SUPERFAMILY SSF53271 11 208 1.97E-54 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CDW54_RS12350 e4dba5c91327a35813290e8cab47b2a2 209 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 11 177 7.3E-48 T 28-03-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CDW54_RS12350 e4dba5c91327a35813290e8cab47b2a2 209 Pfam PF00156 Phosphoribosyl transferase domain 46 155 3.8E-19 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CDW54_RS12350 e4dba5c91327a35813290e8cab47b2a2 209 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 209 31.324 T 28-03-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CDW54_RS12350 e4dba5c91327a35813290e8cab47b2a2 209 Gene3D G3DSA:3.40.50.2020 2 209 7.6E-41 T 28-03-2018 CDW54_RS08040 75198e42b89dbcff9c4ec4e0ef665493 370 SUPERFAMILY SSF51905 307 353 4.01E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS08040 75198e42b89dbcff9c4ec4e0ef665493 370 SUPERFAMILY SSF51905 3 214 4.01E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS08040 75198e42b89dbcff9c4ec4e0ef665493 370 SUPERFAMILY SSF54373 214 306 5.76E-9 T 28-03-2018 CDW54_RS08040 75198e42b89dbcff9c4ec4e0ef665493 370 Gene3D G3DSA:3.50.50.60 2 359 1.3E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS08040 75198e42b89dbcff9c4ec4e0ef665493 370 Pfam PF01266 FAD dependent oxidoreductase 3 345 5.3E-40 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CDW54_RS03620 c253f1b4fb200daaf727e1f83bc67c2b 250 SMART SM00422 3 72 2.4E-20 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CDW54_RS03620 c253f1b4fb200daaf727e1f83bc67c2b 250 Pfam PF07739 TipAS antibiotic-recognition domain 135 247 1.0E-24 T 28-03-2018 IPR012925 TipAS antibiotic-recognition domain CDW54_RS03620 c253f1b4fb200daaf727e1f83bc67c2b 250 SUPERFAMILY SSF89082 155 249 3.4E-21 T 28-03-2018 IPR012925 TipAS antibiotic-recognition domain CDW54_RS03620 c253f1b4fb200daaf727e1f83bc67c2b 250 SUPERFAMILY SSF46955 3 109 4.76E-29 T 28-03-2018 IPR009061 Putative DNA-binding domain CDW54_RS03620 c253f1b4fb200daaf727e1f83bc67c2b 250 Pfam PF13411 MerR HTH family regulatory protein 3 70 2.4E-17 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CDW54_RS03620 c253f1b4fb200daaf727e1f83bc67c2b 250 Gene3D G3DSA:1.10.1660.10 1 144 1.5E-37 T 28-03-2018 CDW54_RS03620 c253f1b4fb200daaf727e1f83bc67c2b 250 Gene3D G3DSA:1.10.490.50 163 250 1.6E-18 T 28-03-2018 CDW54_RS03890 f2ef5d88a03e45c44e25db667bc7dcf7 321 SMART SM00046 4 158 2.4E-5 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CDW54_RS03890 f2ef5d88a03e45c44e25db667bc7dcf7 321 Pfam PF00781 Diacylglycerol kinase catalytic domain 4 134 1.3E-26 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CDW54_RS03890 f2ef5d88a03e45c44e25db667bc7dcf7 321 SUPERFAMILY SSF111331 3 314 3.92E-60 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CDW54_RS03890 f2ef5d88a03e45c44e25db667bc7dcf7 321 Gene3D G3DSA:3.40.50.10330 1 146 4.0E-28 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CDW54_RS00160 b282b887e31a8896b67ddd742dc01bde 306 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 225 279 4.7E-19 T 28-03-2018 IPR019264 Domain of unknown function DUF2179 CDW54_RS00160 b282b887e31a8896b67ddd742dc01bde 306 PIRSF PIRSF006483 1 287 6.8E-88 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT CDW54_RS00160 b282b887e31a8896b67ddd742dc01bde 306 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 13 219 1.2E-56 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT CDW54_RS07175 85ba5f4bd17891772f0508c65e9180da 443 Pfam PF00324 Amino acid permease 15 434 7.9E-80 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CDW54_RS07175 85ba5f4bd17891772f0508c65e9180da 443 PIRSF PIRSF006060 1 440 9.8E-63 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CDW54_RS00540 502efdd78ca1498abbd17ac6bb5b481d 238 Pfam PF00072 Response regulator receiver domain 5 116 7.8E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDW54_RS00540 502efdd78ca1498abbd17ac6bb5b481d 238 Gene3D G3DSA:1.10.10.10 134 237 8.7E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS00540 502efdd78ca1498abbd17ac6bb5b481d 238 Gene3D G3DSA:3.40.50.2300 2 133 2.2E-30 T 28-03-2018 CDW54_RS00540 502efdd78ca1498abbd17ac6bb5b481d 238 SMART SM00448 3 116 7.1E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDW54_RS00540 502efdd78ca1498abbd17ac6bb5b481d 238 SUPERFAMILY SSF46785 173 234 6.17E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS00540 502efdd78ca1498abbd17ac6bb5b481d 238 SUPERFAMILY SSF52172 2 153 7.68E-34 T 28-03-2018 IPR011006 CheY-like superfamily CDW54_RS00540 502efdd78ca1498abbd17ac6bb5b481d 238 PIRSF PIRSF006171 1 230 7.8E-71 T 28-03-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 CDW54_RS06240 48410605bf624a11bdec4ca337044009 317 Pfam PF01497 Periplasmic binding protein 60 293 7.4E-39 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CDW54_RS06240 48410605bf624a11bdec4ca337044009 317 Gene3D G3DSA:3.40.50.1980 158 317 3.2E-37 T 28-03-2018 CDW54_RS06240 48410605bf624a11bdec4ca337044009 317 SUPERFAMILY SSF53807 37 302 1.61E-72 T 28-03-2018 CDW54_RS06240 48410605bf624a11bdec4ca337044009 317 Gene3D G3DSA:3.40.50.1980 39 157 9.0E-33 T 28-03-2018 CDW54_RS02035 1449b04715169231bbeea22b52632d0d 199 Pfam PF04472 Cell division protein SepF 112 183 1.0E-23 T 28-03-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 CDW54_RS02035 1449b04715169231bbeea22b52632d0d 199 Hamap MF_01197 Cell division protein SepF [sepF]. 1 191 18.928 T 28-03-2018 IPR023052 Cell division protein SepF GO:0090529 CDW54_RS05010 59585a2e7547ba6681089b4203304c12 518 TIGRFAM TIGR00277 HDIG: HDIG domain 330 407 1.2E-25 T 28-03-2018 IPR006675 HDIG domain CDW54_RS05010 59585a2e7547ba6681089b4203304c12 518 Gene3D G3DSA:1.10.3210.10 243 453 7.0E-38 T 28-03-2018 CDW54_RS05010 59585a2e7547ba6681089b4203304c12 518 Pfam PF12072 Domain of unknown function (DUF3552) 5 203 3.2E-71 T 28-03-2018 IPR022711 Ribonuclease Y, N-terminal CDW54_RS05010 59585a2e7547ba6681089b4203304c12 518 Hamap MF_00335 Ribonuclease Y [rny]. 3 518 25.729 T 28-03-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 CDW54_RS05010 59585a2e7547ba6681089b4203304c12 518 TIGRFAM TIGR03319 RNase_Y: ribonuclease Y 6 518 3.2E-241 T 28-03-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 CDW54_RS05010 59585a2e7547ba6681089b4203304c12 518 SUPERFAMILY SSF109604 314 465 6.73E-30 T 28-03-2018 CDW54_RS05010 59585a2e7547ba6681089b4203304c12 518 Gene3D G3DSA:3.30.300.20 129 242 1.8E-11 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CDW54_RS05010 59585a2e7547ba6681089b4203304c12 518 SMART SM00322 206 273 2.5E-7 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CDW54_RS05010 59585a2e7547ba6681089b4203304c12 518 SUPERFAMILY SSF54791 207 302 5.35E-17 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CDW54_RS05010 59585a2e7547ba6681089b4203304c12 518 SMART SM00471 330 436 4.8E-13 T 28-03-2018 IPR003607 HD/PDEase domain CDW54_RS05010 59585a2e7547ba6681089b4203304c12 518 Pfam PF01966 HD domain 335 426 1.9E-19 T 28-03-2018 IPR006674 HD domain CDW54_RS05010 59585a2e7547ba6681089b4203304c12 518 Pfam PF00013 KH domain 211 267 8.9E-7 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CDW54_RS12180 8768c19525bea0f77af693a7fa6f71c5 224 Gene3D G3DSA:1.10.10.10 117 224 2.1E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS12180 8768c19525bea0f77af693a7fa6f71c5 224 Pfam PF00072 Response regulator receiver domain 5 112 1.1E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDW54_RS12180 8768c19525bea0f77af693a7fa6f71c5 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 221 3.1E-19 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDW54_RS12180 8768c19525bea0f77af693a7fa6f71c5 224 SMART SM00448 2 112 1.9E-38 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDW54_RS12180 8768c19525bea0f77af693a7fa6f71c5 224 SMART SM00862 146 221 1.7E-18 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDW54_RS12180 8768c19525bea0f77af693a7fa6f71c5 224 SUPERFAMILY SSF52172 1 123 3.84E-37 T 28-03-2018 IPR011006 CheY-like superfamily CDW54_RS12180 8768c19525bea0f77af693a7fa6f71c5 224 SUPERFAMILY SSF46894 123 221 2.41E-24 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDW54_RS12180 8768c19525bea0f77af693a7fa6f71c5 224 Gene3D G3DSA:3.40.50.2300 1 116 3.2E-32 T 28-03-2018 CDW54_RS04140 87518f2ab8dea8e2bae94564ca4c9a3e 394 SUPERFAMILY SSF53067 1 196 1.36E-69 T 28-03-2018 CDW54_RS04140 87518f2ab8dea8e2bae94564ca4c9a3e 394 PIRSF PIRSF000722 1 394 3.1E-155 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CDW54_RS04140 87518f2ab8dea8e2bae94564ca4c9a3e 394 Gene3D G3DSA:3.30.420.40 196 393 1.8E-82 T 28-03-2018 CDW54_RS04140 87518f2ab8dea8e2bae94564ca4c9a3e 394 Pfam PF00871 Acetokinase family 4 387 8.8E-156 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CDW54_RS04140 87518f2ab8dea8e2bae94564ca4c9a3e 394 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 203 220 - T 28-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CDW54_RS04140 87518f2ab8dea8e2bae94564ca4c9a3e 394 PRINTS PR00471 Acetate kinase family signature 203 224 7.4E-46 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CDW54_RS04140 87518f2ab8dea8e2bae94564ca4c9a3e 394 PRINTS PR00471 Acetate kinase family signature 320 336 7.4E-46 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CDW54_RS04140 87518f2ab8dea8e2bae94564ca4c9a3e 394 PRINTS PR00471 Acetate kinase family signature 4 15 7.4E-46 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CDW54_RS04140 87518f2ab8dea8e2bae94564ca4c9a3e 394 PRINTS PR00471 Acetate kinase family signature 173 186 7.4E-46 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CDW54_RS04140 87518f2ab8dea8e2bae94564ca4c9a3e 394 PRINTS PR00471 Acetate kinase family signature 298 311 7.4E-46 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CDW54_RS04140 87518f2ab8dea8e2bae94564ca4c9a3e 394 PRINTS PR00471 Acetate kinase family signature 374 386 7.4E-46 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CDW54_RS04140 87518f2ab8dea8e2bae94564ca4c9a3e 394 Hamap MF_00020 Acetate kinase [ackA]. 1 394 187.789 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CDW54_RS04140 87518f2ab8dea8e2bae94564ca4c9a3e 394 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 4 15 - T 28-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CDW54_RS04140 87518f2ab8dea8e2bae94564ca4c9a3e 394 Gene3D G3DSA:3.30.420.40 3 195 4.0E-74 T 28-03-2018 CDW54_RS04140 87518f2ab8dea8e2bae94564ca4c9a3e 394 SUPERFAMILY SSF53067 157 392 9.81E-93 T 28-03-2018 CDW54_RS04140 87518f2ab8dea8e2bae94564ca4c9a3e 394 TIGRFAM TIGR00016 ackA: acetate kinase 2 392 6.1E-163 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CDW54_RS11120 56335be6b209042e1dbc104ff591fb8d 341 Pfam PF01343 Peptidase family S49 131 281 1.4E-51 T 28-03-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 CDW54_RS11120 56335be6b209042e1dbc104ff591fb8d 341 SUPERFAMILY SSF52096 209 269 1.31E-38 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CDW54_RS11120 56335be6b209042e1dbc104ff591fb8d 341 SUPERFAMILY SSF52096 60 178 1.31E-38 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CDW54_RS11120 56335be6b209042e1dbc104ff591fb8d 341 Gene3D G3DSA:3.90.226.10 52 340 1.2E-42 T 28-03-2018 CDW54_RS11120 56335be6b209042e1dbc104ff591fb8d 341 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 60 279 2.6E-72 T 28-03-2018 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 CDW54_RS10975 7e47eab0de1c25059edbd176f44b1494 388 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 13 375 5.1E-115 T 28-03-2018 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 CDW54_RS10975 7e47eab0de1c25059edbd176f44b1494 388 Gene3D G3DSA:3.20.20.70 4 342 7.8E-50 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDW54_RS10975 7e47eab0de1c25059edbd176f44b1494 388 SUPERFAMILY SSF102114 6 385 3.79E-120 T 28-03-2018 CDW54_RS10975 7e47eab0de1c25059edbd176f44b1494 388 Pfam PF06969 HemN C-terminal domain 310 373 4.5E-16 T 28-03-2018 IPR010723 HemN, C-terminal CDW54_RS10975 7e47eab0de1c25059edbd176f44b1494 388 Pfam PF04055 Radical SAM superfamily 16 185 6.3E-24 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CDW54_RS10975 7e47eab0de1c25059edbd176f44b1494 388 SMART SM00729 11 231 1.1E-59 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CDW54_RS11420 4e38979b9ba06005852cc54373e20749 881 SUPERFAMILY SSF56672 475 881 1.22E-156 T 28-03-2018 CDW54_RS11420 4e38979b9ba06005852cc54373e20749 881 SUPERFAMILY SSF47807 177 293 1.29E-35 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CDW54_RS11420 4e38979b9ba06005852cc54373e20749 881 SMART SM00279 179 214 4.3E-15 T 28-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 CDW54_RS11420 4e38979b9ba06005852cc54373e20749 881 PRINTS PR00868 DNA-polymerase family A (pol I) signature 682 695 2.4E-82 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDW54_RS11420 4e38979b9ba06005852cc54373e20749 881 PRINTS PR00868 DNA-polymerase family A (pol I) signature 652 675 2.4E-82 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDW54_RS11420 4e38979b9ba06005852cc54373e20749 881 PRINTS PR00868 DNA-polymerase family A (pol I) signature 828 841 2.4E-82 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDW54_RS11420 4e38979b9ba06005852cc54373e20749 881 PRINTS PR00868 DNA-polymerase family A (pol I) signature 766 777 2.4E-82 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDW54_RS11420 4e38979b9ba06005852cc54373e20749 881 PRINTS PR00868 DNA-polymerase family A (pol I) signature 707 732 2.4E-82 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDW54_RS11420 4e38979b9ba06005852cc54373e20749 881 PRINTS PR00868 DNA-polymerase family A (pol I) signature 798 814 2.4E-82 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDW54_RS11420 4e38979b9ba06005852cc54373e20749 881 PRINTS PR00868 DNA-polymerase family A (pol I) signature 606 628 2.4E-82 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDW54_RS11420 4e38979b9ba06005852cc54373e20749 881 PRINTS PR00868 DNA-polymerase family A (pol I) signature 744 755 2.4E-82 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDW54_RS11420 4e38979b9ba06005852cc54373e20749 881 PRINTS PR00868 DNA-polymerase family A (pol I) signature 629 644 2.4E-82 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDW54_RS11420 4e38979b9ba06005852cc54373e20749 881 SMART SM00475 4 268 4.5E-144 T 28-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 CDW54_RS11420 4e38979b9ba06005852cc54373e20749 881 SMART SM00474 304 471 4.2E-8 T 28-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 CDW54_RS11420 4e38979b9ba06005852cc54373e20749 881 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 178 270 2.8E-35 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CDW54_RS11420 4e38979b9ba06005852cc54373e20749 881 ProSitePatterns PS00447 DNA polymerase family A signature. 707 726 - T 28-03-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDW54_RS11420 4e38979b9ba06005852cc54373e20749 881 Gene3D G3DSA:3.30.70.370 608 695 1.1E-13 T 28-03-2018 CDW54_RS11420 4e38979b9ba06005852cc54373e20749 881 Gene3D G3DSA:3.30.70.370 707 881 2.9E-54 T 28-03-2018 CDW54_RS11420 4e38979b9ba06005852cc54373e20749 881 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 5 174 1.1E-50 T 28-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 CDW54_RS11420 4e38979b9ba06005852cc54373e20749 881 SMART SM00482 637 845 1.9E-120 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDW54_RS11420 4e38979b9ba06005852cc54373e20749 881 Gene3D G3DSA:3.30.420.10 292 495 4.8E-22 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS11420 4e38979b9ba06005852cc54373e20749 881 TIGRFAM TIGR00593 pola: DNA polymerase I 6 881 0.0 T 28-03-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDW54_RS11420 4e38979b9ba06005852cc54373e20749 881 Gene3D G3DSA:1.10.150.20 191 269 4.9E-32 T 28-03-2018 CDW54_RS11420 4e38979b9ba06005852cc54373e20749 881 Gene3D G3DSA:3.40.50.1010 4 190 8.7E-63 T 28-03-2018 IPR029060 PIN domain-like CDW54_RS11420 4e38979b9ba06005852cc54373e20749 881 Pfam PF00476 DNA polymerase family A 504 879 5.2E-159 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDW54_RS11420 4e38979b9ba06005852cc54373e20749 881 SUPERFAMILY SSF88723 3 175 8.41E-50 T 28-03-2018 IPR029060 PIN domain-like CDW54_RS11420 4e38979b9ba06005852cc54373e20749 881 SUPERFAMILY SSF53098 306 471 6.53E-39 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS11420 4e38979b9ba06005852cc54373e20749 881 Gene3D G3DSA:1.20.1060.10 496 607 3.6E-34 T 28-03-2018 CDW54_RS06020 80f91fc892c8d2afb035cfa75e239a81 431 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 426 6.3E-141 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CDW54_RS06020 80f91fc892c8d2afb035cfa75e239a81 431 ProSitePatterns PS00755 Protein secY signature 1. 68 87 - T 28-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CDW54_RS06020 80f91fc892c8d2afb035cfa75e239a81 431 Pfam PF00344 SecY translocase 68 413 7.4E-107 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CDW54_RS06020 80f91fc892c8d2afb035cfa75e239a81 431 SUPERFAMILY SSF103491 3 420 8.76E-126 T 28-03-2018 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CDW54_RS06020 80f91fc892c8d2afb035cfa75e239a81 431 PIRSF PIRSF004557 1 429 3.2E-123 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CDW54_RS06020 80f91fc892c8d2afb035cfa75e239a81 431 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 430 28.235 T 28-03-2018 IPR026593 Protein translocase subunit SecY CDW54_RS06020 80f91fc892c8d2afb035cfa75e239a81 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 365 383 7.0E-94 T 28-03-2018 CDW54_RS06020 80f91fc892c8d2afb035cfa75e239a81 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 266 285 7.0E-94 T 28-03-2018 CDW54_RS06020 80f91fc892c8d2afb035cfa75e239a81 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 67 87 7.0E-94 T 28-03-2018 CDW54_RS06020 80f91fc892c8d2afb035cfa75e239a81 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 399 417 7.0E-94 T 28-03-2018 CDW54_RS06020 80f91fc892c8d2afb035cfa75e239a81 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 310 332 7.0E-94 T 28-03-2018 CDW54_RS06020 80f91fc892c8d2afb035cfa75e239a81 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 7.0E-94 T 28-03-2018 CDW54_RS06020 80f91fc892c8d2afb035cfa75e239a81 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 172 195 7.0E-94 T 28-03-2018 CDW54_RS06020 80f91fc892c8d2afb035cfa75e239a81 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 146 171 7.0E-94 T 28-03-2018 CDW54_RS06020 80f91fc892c8d2afb035cfa75e239a81 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 109 132 7.0E-94 T 28-03-2018 CDW54_RS06020 80f91fc892c8d2afb035cfa75e239a81 431 Gene3D G3DSA:1.10.3370.10 1 431 2.6E-143 T 28-03-2018 CDW54_RS12615 7c9604cc64b400f491b1dfce5d4dcc97 170 Gene3D G3DSA:3.40.50.2020 1 168 3.4E-41 T 28-03-2018 CDW54_RS12615 7c9604cc64b400f491b1dfce5d4dcc97 170 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 3 170 38.072 T 28-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 CDW54_RS12615 7c9604cc64b400f491b1dfce5d4dcc97 170 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 3 170 6.9E-71 T 28-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 CDW54_RS12615 7c9604cc64b400f491b1dfce5d4dcc97 170 SUPERFAMILY SSF53271 2 163 4.12E-51 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CDW54_RS12615 7c9604cc64b400f491b1dfce5d4dcc97 170 Pfam PF00156 Phosphoribosyl transferase domain 31 150 2.9E-20 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CDW54_RS03035 487c2f6d4355192785f5ed9bc99f67b0 220 SUPERFAMILY SSF52540 1 214 1.47E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS03035 487c2f6d4355192785f5ed9bc99f67b0 220 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS03035 487c2f6d4355192785f5ed9bc99f67b0 220 SMART SM00382 28 213 3.1E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS03035 487c2f6d4355192785f5ed9bc99f67b0 220 Pfam PF00005 ABC transporter 19 165 8.0E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS03035 487c2f6d4355192785f5ed9bc99f67b0 220 Gene3D G3DSA:3.40.50.300 1 219 7.8E-56 T 28-03-2018 CDW54_RS05200 22acdcb155c3e5b3a77e265c93b3ae23 327 Pfam PF01207 Dihydrouridine synthase (Dus) 15 317 3.1E-50 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CDW54_RS05200 22acdcb155c3e5b3a77e265c93b3ae23 327 Gene3D G3DSA:3.20.20.70 10 248 3.5E-36 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDW54_RS05200 22acdcb155c3e5b3a77e265c93b3ae23 327 SUPERFAMILY SSF51395 13 319 4.3E-59 T 28-03-2018 CDW54_RS05200 22acdcb155c3e5b3a77e265c93b3ae23 327 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 99 117 - T 28-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 CDW54_RS05200 22acdcb155c3e5b3a77e265c93b3ae23 327 PIRSF PIRSF006621 1 326 2.1E-81 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CDW54_RS05200 22acdcb155c3e5b3a77e265c93b3ae23 327 Gene3D G3DSA:1.10.1200.80 250 325 2.4E-11 T 28-03-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 CDW54_RS06855 33e839d19cf1b8c69e7e52b6d34cce80 319 Gene3D G3DSA:1.10.10.60 6 68 1.1E-4 T 28-03-2018 CDW54_RS06855 33e839d19cf1b8c69e7e52b6d34cce80 319 Pfam PF00665 Integrase core domain 167 265 7.8E-10 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CDW54_RS06855 33e839d19cf1b8c69e7e52b6d34cce80 319 SUPERFAMILY SSF53098 160 309 4.17E-21 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS06855 33e839d19cf1b8c69e7e52b6d34cce80 319 Gene3D G3DSA:3.30.420.10 155 317 1.3E-21 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS00240 6a4e945b7ac1996b6c39020c6705ba36 347 Gene3D G3DSA:3.30.230.10 56 347 6.0E-38 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CDW54_RS00240 6a4e945b7ac1996b6c39020c6705ba36 347 Pfam PF13180 PDZ domain 130 194 1.2E-11 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CDW54_RS00240 6a4e945b7ac1996b6c39020c6705ba36 347 SUPERFAMILY SSF54211 159 343 1.82E-22 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CDW54_RS00240 6a4e945b7ac1996b6c39020c6705ba36 347 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 220 305 6.6E-9 T 28-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 CDW54_RS03130 8305b37e0f415a8f5ca8d2a9e0660f99 587 SUPERFAMILY SSF52540 340 584 1.78E-89 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS03130 8305b37e0f415a8f5ca8d2a9e0660f99 587 Pfam PF00005 ABC transporter 365 513 3.0E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS03130 8305b37e0f415a8f5ca8d2a9e0660f99 587 Gene3D G3DSA:1.20.1560.10 1 333 9.3E-69 T 28-03-2018 CDW54_RS03130 8305b37e0f415a8f5ca8d2a9e0660f99 587 Pfam PF00664 ABC transporter transmembrane region 26 300 4.5E-46 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CDW54_RS03130 8305b37e0f415a8f5ca8d2a9e0660f99 587 Gene3D G3DSA:3.40.50.300 335 587 7.8E-75 T 28-03-2018 CDW54_RS03130 8305b37e0f415a8f5ca8d2a9e0660f99 587 SMART SM00382 373 559 1.9E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS03130 8305b37e0f415a8f5ca8d2a9e0660f99 587 SUPERFAMILY SSF90123 12 331 8.37E-73 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CDW54_RS11945 03449202683ab06a4b093162cc6c8db9 360 Hamap MF_00106 Mannonate dehydratase [uxuA]. 1 360 162.636 T 28-03-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 CDW54_RS11945 03449202683ab06a4b093162cc6c8db9 360 TIGRFAM TIGR00695 uxuA: mannonate dehydratase 1 357 5.4E-117 T 28-03-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 CDW54_RS11945 03449202683ab06a4b093162cc6c8db9 360 Gene3D G3DSA:3.20.20.150 1 360 4.5E-104 T 28-03-2018 CDW54_RS11945 03449202683ab06a4b093162cc6c8db9 360 SUPERFAMILY SSF51658 1 351 2.76E-88 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CDW54_RS11945 03449202683ab06a4b093162cc6c8db9 360 PIRSF PIRSF016049 1 167 3.0E-47 T 28-03-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 CDW54_RS11945 03449202683ab06a4b093162cc6c8db9 360 PIRSF PIRSF016049 154 358 9.0E-73 T 28-03-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 CDW54_RS11945 03449202683ab06a4b093162cc6c8db9 360 Pfam PF03786 D-mannonate dehydratase (UxuA) 1 353 6.7E-156 T 28-03-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 CDW54_RS02130 656f6badafd56af1610b6aaead7298d7 74 Gene3D G3DSA:1.10.287.1040 3 68 1.3E-24 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CDW54_RS02130 656f6badafd56af1610b6aaead7298d7 74 Pfam PF02609 Exonuclease VII small subunit 6 57 3.2E-21 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CDW54_RS02130 656f6badafd56af1610b6aaead7298d7 74 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 2 47 2.0E-20 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CDW54_RS02130 656f6badafd56af1610b6aaead7298d7 74 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 5 65 15.767 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CDW54_RS02130 656f6badafd56af1610b6aaead7298d7 74 PIRSF PIRSF006488 1 74 4.8E-22 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CDW54_RS02130 656f6badafd56af1610b6aaead7298d7 74 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 5 61 1.1E-23 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CDW54_RS02130 656f6badafd56af1610b6aaead7298d7 74 SUPERFAMILY SSF116842 2 69 4.05E-21 T 28-03-2018 CDW54_RS01555 4835a41d02450e682bbe58b219055c93 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CDW54_RS01555 4835a41d02450e682bbe58b219055c93 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 241 2.1E-65 T 28-03-2018 CDW54_RS01555 4835a41d02450e682bbe58b219055c93 245 Gene3D G3DSA:3.40.50.720 45 245 3.1E-67 T 28-03-2018 CDW54_RS01555 4835a41d02450e682bbe58b219055c93 245 Gene3D G3DSA:3.40.50.720 1 44 1.3E-9 T 28-03-2018 CDW54_RS01555 4835a41d02450e682bbe58b219055c93 245 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 8 242 3.5E-96 T 28-03-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CDW54_RS01555 4835a41d02450e682bbe58b219055c93 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 3.1E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS01555 4835a41d02450e682bbe58b219055c93 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 3.1E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS01555 4835a41d02450e682bbe58b219055c93 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 3.1E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS01555 4835a41d02450e682bbe58b219055c93 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 3.1E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS01555 4835a41d02450e682bbe58b219055c93 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 3.1E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS01555 4835a41d02450e682bbe58b219055c93 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 3.1E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS01555 4835a41d02450e682bbe58b219055c93 245 SUPERFAMILY SSF51735 4 244 1.36E-83 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS01555 4835a41d02450e682bbe58b219055c93 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 2.5E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS01555 4835a41d02450e682bbe58b219055c93 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 2.5E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS01555 4835a41d02450e682bbe58b219055c93 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 2.5E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS01555 4835a41d02450e682bbe58b219055c93 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 184 5.5E-7 T 28-03-2018 CDW54_RS10170 da6bdc777fde66230f5afa37a098d5e2 435 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 121 138 3.3E-8 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CDW54_RS10170 da6bdc777fde66230f5afa37a098d5e2 435 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 64 75 3.3E-8 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CDW54_RS10170 da6bdc777fde66230f5afa37a098d5e2 435 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 148 161 3.3E-8 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CDW54_RS10170 da6bdc777fde66230f5afa37a098d5e2 435 SUPERFAMILY SSF56601 5 308 7.57E-72 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CDW54_RS10170 da6bdc777fde66230f5afa37a098d5e2 435 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 29 284 5.2E-72 T 28-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CDW54_RS10170 da6bdc777fde66230f5afa37a098d5e2 435 Gene3D G3DSA:2.60.410.10 311 416 3.7E-17 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CDW54_RS10170 da6bdc777fde66230f5afa37a098d5e2 435 SMART SM00936 308 416 2.3E-12 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CDW54_RS10170 da6bdc777fde66230f5afa37a098d5e2 435 Gene3D G3DSA:3.40.710.10 25 308 4.6E-50 T 28-03-2018 CDW54_RS10170 da6bdc777fde66230f5afa37a098d5e2 435 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 309 416 2.1E-12 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CDW54_RS10170 da6bdc777fde66230f5afa37a098d5e2 435 SUPERFAMILY SSF69189 300 396 1.08E-10 T 28-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CDW54_RS11015 23e989ba0ea0dc921c5f2f21298adfd6 938 Gene3D G3DSA:1.10.8.280 284 403 2.8E-38 T 28-03-2018 CDW54_RS11015 23e989ba0ea0dc921c5f2f21298adfd6 938 ProSitePatterns PS00211 ABC transporters family signature. 486 500 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS11015 23e989ba0ea0dc921c5f2f21298adfd6 938 SMART SM00382 630 905 4.3E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS11015 23e989ba0ea0dc921c5f2f21298adfd6 938 Gene3D G3DSA:3.40.50.300 429 616 5.5E-21 T 28-03-2018 CDW54_RS11015 23e989ba0ea0dc921c5f2f21298adfd6 938 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 5 922 0.0 T 28-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CDW54_RS11015 23e989ba0ea0dc921c5f2f21298adfd6 938 Gene3D G3DSA:3.40.50.300 37 137 3.0E-4 T 28-03-2018 CDW54_RS11015 23e989ba0ea0dc921c5f2f21298adfd6 938 Gene3D G3DSA:3.40.50.300 617 937 2.1E-58 T 28-03-2018 CDW54_RS11015 23e989ba0ea0dc921c5f2f21298adfd6 938 Hamap MF_00205 UvrABC system protein A [uvrA]. 3 937 23.046 T 28-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CDW54_RS11015 23e989ba0ea0dc921c5f2f21298adfd6 938 SUPERFAMILY SSF52540 429 568 7.93E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS11015 23e989ba0ea0dc921c5f2f21298adfd6 938 SUPERFAMILY SSF52540 6 206 7.93E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS11015 23e989ba0ea0dc921c5f2f21298adfd6 938 Pfam PF00005 ABC transporter 621 857 4.9E-12 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS11015 23e989ba0ea0dc921c5f2f21298adfd6 938 SUPERFAMILY SSF52540 611 911 1.86E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS11015 23e989ba0ea0dc921c5f2f21298adfd6 938 ProSitePatterns PS00211 ABC transporters family signature. 827 841 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS11015 23e989ba0ea0dc921c5f2f21298adfd6 938 Gene3D G3DSA:3.40.50.300 2 36 0.0075 T 28-03-2018 CDW54_RS11015 23e989ba0ea0dc921c5f2f21298adfd6 938 Gene3D G3DSA:3.30.190.20 138 247 2.3E-44 T 28-03-2018 CDW54_RS11130 d5887fe00c79d3625ebeae2201c0edc3 310 Gene3D G3DSA:1.25.40.10 4 256 7.6E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDW54_RS06340 09f11c5ea3bc17f3a282ddd4e1ba2fcc 211 SUPERFAMILY SSF48371 8 211 6.91E-45 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CDW54_RS06340 09f11c5ea3bc17f3a282ddd4e1ba2fcc 211 Pfam PF08713 DNA alkylation repair enzyme 8 211 7.4E-48 T 28-03-2018 IPR014825 DNA alkylation repair enzyme CDW54_RS06340 09f11c5ea3bc17f3a282ddd4e1ba2fcc 211 Gene3D G3DSA:1.20.1660.10 4 118 2.5E-19 T 28-03-2018 CDW54_RS06340 09f11c5ea3bc17f3a282ddd4e1ba2fcc 211 Gene3D G3DSA:1.25.40.290 119 211 3.9E-18 T 28-03-2018 CDW54_RS11565 ed11c79b29c4228dd6a7c840ff92c868 65 Gene3D G3DSA:2.40.50.140 1 65 5.7E-27 T 28-03-2018 CDW54_RS11565 ed11c79b29c4228dd6a7c840ff92c868 65 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 2.2E-29 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CDW54_RS11565 ed11c79b29c4228dd6a7c840ff92c868 65 SMART SM00357 3 65 6.2E-27 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CDW54_RS11565 ed11c79b29c4228dd6a7c840ff92c868 65 PIRSF PIRSF002599 1 65 6.9E-23 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 CDW54_RS11565 ed11c79b29c4228dd6a7c840ff92c868 65 SUPERFAMILY SSF50249 1 64 3.86E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDW54_RS11565 ed11c79b29c4228dd6a7c840ff92c868 65 PRINTS PR00050 Cold shock protein signature 4 19 4.5E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CDW54_RS11565 ed11c79b29c4228dd6a7c840ff92c868 65 PRINTS PR00050 Cold shock protein signature 39 57 4.5E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CDW54_RS11565 ed11c79b29c4228dd6a7c840ff92c868 65 PRINTS PR00050 Cold shock protein signature 24 33 4.5E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CDW54_RS11565 ed11c79b29c4228dd6a7c840ff92c868 65 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 28-03-2018 IPR019844 Cold-shock conserved site CDW54_RS03720 ed11c79b29c4228dd6a7c840ff92c868 65 Gene3D G3DSA:2.40.50.140 1 65 5.7E-27 T 28-03-2018 CDW54_RS03720 ed11c79b29c4228dd6a7c840ff92c868 65 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 2.2E-29 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CDW54_RS03720 ed11c79b29c4228dd6a7c840ff92c868 65 SMART SM00357 3 65 6.2E-27 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CDW54_RS03720 ed11c79b29c4228dd6a7c840ff92c868 65 PIRSF PIRSF002599 1 65 6.9E-23 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 CDW54_RS03720 ed11c79b29c4228dd6a7c840ff92c868 65 SUPERFAMILY SSF50249 1 64 3.86E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDW54_RS03720 ed11c79b29c4228dd6a7c840ff92c868 65 PRINTS PR00050 Cold shock protein signature 4 19 4.5E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CDW54_RS03720 ed11c79b29c4228dd6a7c840ff92c868 65 PRINTS PR00050 Cold shock protein signature 39 57 4.5E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CDW54_RS03720 ed11c79b29c4228dd6a7c840ff92c868 65 PRINTS PR00050 Cold shock protein signature 24 33 4.5E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CDW54_RS03720 ed11c79b29c4228dd6a7c840ff92c868 65 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 28-03-2018 IPR019844 Cold-shock conserved site CDW54_RS03205 4c6b62b405d6004a6f05498f3c231083 317 Gene3D G3DSA:3.40.50.300 2 314 1.2E-77 T 28-03-2018 CDW54_RS03205 4c6b62b405d6004a6f05498f3c231083 317 Pfam PF00005 ABC transporter 27 179 2.9E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS03205 4c6b62b405d6004a6f05498f3c231083 317 SUPERFAMILY SSF52540 5 250 5.2E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS03205 4c6b62b405d6004a6f05498f3c231083 317 SMART SM00382 35 229 7.4E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS03205 4c6b62b405d6004a6f05498f3c231083 317 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS00075 2442d5eb0009c11383ae72577c1658f9 252 Gene3D G3DSA:3.90.70.10 70 252 6.1E-21 T 28-03-2018 CDW54_RS00075 2442d5eb0009c11383ae72577c1658f9 252 PIRSF PIRSF032442 1 251 1.9E-77 T 28-03-2018 IPR016997 Uncharacterised conserved protein UCP032442 CDW54_RS00075 2442d5eb0009c11383ae72577c1658f9 252 SUPERFAMILY SSF54001 143 226 8.07E-5 T 28-03-2018 CDW54_RS00075 2442d5eb0009c11383ae72577c1658f9 252 Pfam PF13529 Peptidase_C39 like family 58 223 3.9E-36 T 28-03-2018 CDW54_RS03960 c6ffb65802a41c4c28493456d0ec0158 265 Hamap MF_00361 NAD kinase [nadK]. 1 263 25.302 T 28-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CDW54_RS03960 c6ffb65802a41c4c28493456d0ec0158 265 SUPERFAMILY SSF111331 22 261 4.19E-63 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CDW54_RS03960 c6ffb65802a41c4c28493456d0ec0158 265 Gene3D G3DSA:3.40.50.10330 1 123 2.9E-28 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CDW54_RS03960 c6ffb65802a41c4c28493456d0ec0158 265 Gene3D G3DSA:2.60.200.30 124 237 4.9E-26 T 28-03-2018 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CDW54_RS03960 c6ffb65802a41c4c28493456d0ec0158 265 Pfam PF01513 ATP-NAD kinase 23 222 1.6E-27 T 28-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CDW54_RS01520 0fb710af30d8c31f32a085ae716a6d54 175 Gene3D G3DSA:3.40.50.1000 15 148 2.1E-22 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS01520 0fb710af30d8c31f32a085ae716a6d54 175 TIGRFAM TIGR01668 YqeG_hyp_ppase: HAD phosphatase, family IIIA 6 164 6.5E-39 T 28-03-2018 IPR010021 HAD-superfamily phosphatase, YqeG-like CDW54_RS01520 0fb710af30d8c31f32a085ae716a6d54 175 SUPERFAMILY SSF56784 2 150 8.14E-27 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS01520 0fb710af30d8c31f32a085ae716a6d54 175 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 28 138 3.6E-19 T 28-03-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 CDW54_RS01520 0fb710af30d8c31f32a085ae716a6d54 175 Pfam PF13242 HAD-hyrolase-like 92 137 4.6E-11 T 28-03-2018 CDW54_RS01520 0fb710af30d8c31f32a085ae716a6d54 175 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 58 130 4.6E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDW54_RS10395 9212232b7ad722da291841e3d8206bd2 91 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 80 1.6E-36 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS10395 9212232b7ad722da291841e3d8206bd2 91 Pfam PF00886 Ribosomal protein S16 9 67 6.0E-26 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS10395 9212232b7ad722da291841e3d8206bd2 91 Gene3D G3DSA:3.30.1320.10 2 85 1.6E-35 T 28-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS10395 9212232b7ad722da291841e3d8206bd2 91 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 25.464 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS10395 9212232b7ad722da291841e3d8206bd2 91 SUPERFAMILY SSF54565 2 87 7.06E-36 T 28-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS09300 3bbaec767d6e323a13d2674728b037de 367 Pfam PF01070 FMN-dependent dehydrogenase 26 358 7.8E-106 T 28-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 CDW54_RS09300 3bbaec767d6e323a13d2674728b037de 367 PIRSF PIRSF000138 1 366 1.4E-125 T 28-03-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 CDW54_RS09300 3bbaec767d6e323a13d2674728b037de 367 Gene3D G3DSA:3.20.20.70 15 366 5.0E-91 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDW54_RS09300 3bbaec767d6e323a13d2674728b037de 367 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 259 265 - T 28-03-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 CDW54_RS09300 3bbaec767d6e323a13d2674728b037de 367 SUPERFAMILY SSF51395 16 358 1.04E-84 T 28-03-2018 CDW54_RS09385 653dc25a95af322abc2e9c93c79957ea 786 Gene3D G3DSA:3.40.50.300 291 555 1.0E-35 T 28-03-2018 CDW54_RS09385 653dc25a95af322abc2e9c93c79957ea 786 TIGRFAM TIGR01069 mutS2: MutS2 family protein 1 785 3.0E-242 T 28-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 CDW54_RS09385 653dc25a95af322abc2e9c93c79957ea 786 PIRSF PIRSF005814 1 786 4.1E-266 T 28-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 CDW54_RS09385 653dc25a95af322abc2e9c93c79957ea 786 Hamap MF_00092 Endonuclease MutS2 [mutS2]. 2 785 21.876 T 28-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 CDW54_RS09385 653dc25a95af322abc2e9c93c79957ea 786 SUPERFAMILY SSF48334 23 285 1.18E-25 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CDW54_RS09385 653dc25a95af322abc2e9c93c79957ea 786 SUPERFAMILY SSF52540 292 514 5.63E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS09385 653dc25a95af322abc2e9c93c79957ea 786 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 409 425 - T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CDW54_RS09385 653dc25a95af322abc2e9c93c79957ea 786 SMART SM00463 708 786 3.6E-22 T 28-03-2018 IPR002625 Smr domain CDW54_RS09385 653dc25a95af322abc2e9c93c79957ea 786 Pfam PF01713 Smr domain 711 786 2.0E-21 T 28-03-2018 IPR002625 Smr domain CDW54_RS09385 653dc25a95af322abc2e9c93c79957ea 786 Gene3D G3DSA:1.10.1420.10 21 289 0.0052 T 28-03-2018 CDW54_RS09385 653dc25a95af322abc2e9c93c79957ea 786 SUPERFAMILY SSF160443 709 785 2.22E-10 T 28-03-2018 IPR002625 Smr domain CDW54_RS09385 653dc25a95af322abc2e9c93c79957ea 786 SMART SM00534 327 512 4.7E-77 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CDW54_RS09385 653dc25a95af322abc2e9c93c79957ea 786 SMART SM00533 9 314 2.3E-13 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CDW54_RS09385 653dc25a95af322abc2e9c93c79957ea 786 Pfam PF00488 MutS domain V 330 512 1.5E-33 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CDW54_RS08325 5d98b40f61a7ebcdacfc3712cd94b6fb 228 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 42 226 2.1E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS08325 5d98b40f61a7ebcdacfc3712cd94b6fb 228 SUPERFAMILY SSF161098 20 213 2.75E-42 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS08325 5d98b40f61a7ebcdacfc3712cd94b6fb 228 Gene3D G3DSA:1.10.3720.10 13 228 1.4E-38 T 28-03-2018 CDW54_RS09645 88abd75ad785cfa5693f6e50427e1642 180 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 140 159 - T 28-03-2018 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS09645 88abd75ad785cfa5693f6e50427e1642 180 SUPERFAMILY SSF47928 5 107 1.44E-23 T 28-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS09645 88abd75ad785cfa5693f6e50427e1642 180 Hamap MF_01416 ATP synthase subunit delta [atpD]. 4 180 18.983 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS09645 88abd75ad785cfa5693f6e50427e1642 180 PRINTS PR00125 ATP synthase delta subunit signature 153 171 4.2E-21 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS09645 88abd75ad785cfa5693f6e50427e1642 180 PRINTS PR00125 ATP synthase delta subunit signature 87 101 4.2E-21 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS09645 88abd75ad785cfa5693f6e50427e1642 180 PRINTS PR00125 ATP synthase delta subunit signature 76 87 4.2E-21 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS09645 88abd75ad785cfa5693f6e50427e1642 180 PRINTS PR00125 ATP synthase delta subunit signature 8 27 4.2E-21 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS09645 88abd75ad785cfa5693f6e50427e1642 180 PRINTS PR00125 ATP synthase delta subunit signature 138 153 4.2E-21 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS09645 88abd75ad785cfa5693f6e50427e1642 180 Gene3D G3DSA:1.10.520.20 4 108 1.1E-20 T 28-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS09645 88abd75ad785cfa5693f6e50427e1642 180 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 8 178 7.8E-34 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS09645 88abd75ad785cfa5693f6e50427e1642 180 Pfam PF00213 ATP synthase delta (OSCP) subunit 8 178 7.7E-48 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS06810 b40be80adad7f83d6e1b8ef1c7a2f035 315 SUPERFAMILY SSF53448 4 260 3.58E-36 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDW54_RS06810 b40be80adad7f83d6e1b8ef1c7a2f035 315 Pfam PF00535 Glycosyl transferase family 2 9 161 1.1E-17 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CDW54_RS06810 b40be80adad7f83d6e1b8ef1c7a2f035 315 Gene3D G3DSA:3.90.550.10 1 235 6.7E-25 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDW54_RS08770 3be4cd3a478ea012554a88faabe5717c 621 Pfam PF02378 Phosphotransferase system, EIIC 104 386 6.1E-31 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CDW54_RS08770 3be4cd3a478ea012554a88faabe5717c 621 SUPERFAMILY SSF51261 471 619 1.38E-55 T 28-03-2018 IPR011055 Duplicated hybrid motif CDW54_RS08770 3be4cd3a478ea012554a88faabe5717c 621 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 476 595 6.8E-45 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CDW54_RS08770 3be4cd3a478ea012554a88faabe5717c 621 Gene3D G3DSA:2.70.70.10 462 621 4.7E-60 T 28-03-2018 CDW54_RS08770 3be4cd3a478ea012554a88faabe5717c 621 SUPERFAMILY SSF55604 9 79 4.97E-20 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CDW54_RS08770 3be4cd3a478ea012554a88faabe5717c 621 TIGRFAM TIGR01995 PTS-II-ABC-beta: PTS system, beta-glucoside-specific IIABC component 5 619 3.2E-233 T 28-03-2018 IPR011297 Phosphotransferase system, beta-glucoside-specific IIABC component GO:0005886|GO:0008982|GO:0009401 CDW54_RS08770 3be4cd3a478ea012554a88faabe5717c 621 Gene3D G3DSA:3.30.1360.60 4 79 2.1E-25 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CDW54_RS08770 3be4cd3a478ea012554a88faabe5717c 621 Pfam PF00367 phosphotransferase system, EIIB 10 41 8.8E-13 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CDW54_RS08770 3be4cd3a478ea012554a88faabe5717c 621 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 474 598 1.8E-52 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CDW54_RS08770 3be4cd3a478ea012554a88faabe5717c 621 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 19 36 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CDW54_RS08770 3be4cd3a478ea012554a88faabe5717c 621 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 537 549 - T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CDW54_RS05965 6e68301ab44d00fe0d1e4dacf52a11f2 88 ProSitePatterns PS00056 Ribosomal protein S17 signature. 59 71 - T 28-03-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS05965 6e68301ab44d00fe0d1e4dacf52a11f2 88 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 8 76 3.0E-34 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS05965 6e68301ab44d00fe0d1e4dacf52a11f2 88 Gene3D G3DSA:2.40.50.140 8 85 2.3E-32 T 28-03-2018 CDW54_RS05965 6e68301ab44d00fe0d1e4dacf52a11f2 88 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 8 83 24.27 T 28-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS05965 6e68301ab44d00fe0d1e4dacf52a11f2 88 PRINTS PR00973 Ribosomal protein S17 family signature 69 76 2.0E-11 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS05965 6e68301ab44d00fe0d1e4dacf52a11f2 88 PRINTS PR00973 Ribosomal protein S17 family signature 27 50 2.0E-11 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS05965 6e68301ab44d00fe0d1e4dacf52a11f2 88 PRINTS PR00973 Ribosomal protein S17 family signature 59 69 2.0E-11 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS05965 6e68301ab44d00fe0d1e4dacf52a11f2 88 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 8 78 5.1E-36 T 28-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS05965 6e68301ab44d00fe0d1e4dacf52a11f2 88 SUPERFAMILY SSF50249 8 85 4.2E-32 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDW54_RS05965 6e68301ab44d00fe0d1e4dacf52a11f2 88 Pfam PF00366 Ribosomal protein S17 13 80 2.3E-33 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS06055 a43444ab4ae55d8d3a082dadcec92048 126 ProSitePatterns PS01167 Ribosomal protein L17 signature. 30 52 - T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS06055 a43444ab4ae55d8d3a082dadcec92048 126 Gene3D G3DSA:3.90.1030.10 1 126 3.4E-47 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS06055 a43444ab4ae55d8d3a082dadcec92048 126 TIGRFAM TIGR00059 L17: ribosomal protein bL17 2 126 5.3E-47 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS06055 a43444ab4ae55d8d3a082dadcec92048 126 Pfam PF01196 Ribosomal protein L17 16 126 3.7E-39 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS06055 a43444ab4ae55d8d3a082dadcec92048 126 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 1 126 27.602 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS06055 a43444ab4ae55d8d3a082dadcec92048 126 SUPERFAMILY SSF64263 2 126 3.79E-43 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS11180 36c61d24097ed6304cbaf82a9c8eed5c 745 Pfam PF13361 UvrD-like helicase C-terminal domain 279 622 3.7E-74 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CDW54_RS11180 36c61d24097ed6304cbaf82a9c8eed5c 745 Gene3D G3DSA:1.10.10.160 130 189 2.8E-23 T 28-03-2018 CDW54_RS11180 36c61d24097ed6304cbaf82a9c8eed5c 745 Pfam PF00580 UvrD/REP helicase N-terminal domain 11 274 7.8E-82 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CDW54_RS11180 36c61d24097ed6304cbaf82a9c8eed5c 745 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 7 743 0.0 T 28-03-2018 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 CDW54_RS11180 36c61d24097ed6304cbaf82a9c8eed5c 745 SUPERFAMILY SSF52540 7 651 8.33E-182 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS11180 36c61d24097ed6304cbaf82a9c8eed5c 745 Gene3D G3DSA:3.40.50.300 203 687 5.9E-96 T 28-03-2018 CDW54_RS11180 36c61d24097ed6304cbaf82a9c8eed5c 745 Gene3D G3DSA:3.40.50.300 2 129 1.1E-27 T 28-03-2018 CDW54_RS02360 37cc2d40d7727556ffe4ebf33c44c2f8 581 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 356 5.3E-142 T 28-03-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 CDW54_RS02360 37cc2d40d7727556ffe4ebf33c44c2f8 581 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 233 363 2.3E-13 T 28-03-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 CDW54_RS02360 37cc2d40d7727556ffe4ebf33c44c2f8 581 Gene3D G3DSA:3.40.50.300 1 166 1.7E-40 T 28-03-2018 CDW54_RS02360 37cc2d40d7727556ffe4ebf33c44c2f8 581 SUPERFAMILY SSF52540 32 223 2.25E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS02360 37cc2d40d7727556ffe4ebf33c44c2f8 581 SMART SM00382 37 179 3.7E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS02360 37cc2d40d7727556ffe4ebf33c44c2f8 581 Gene3D G3DSA:1.20.272.10 243 363 9.4E-16 T 28-03-2018 CDW54_RS02360 37cc2d40d7727556ffe4ebf33c44c2f8 581 SUPERFAMILY SSF48019 244 365 1.13E-27 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CDW54_RS02360 37cc2d40d7727556ffe4ebf33c44c2f8 581 Gene3D G3DSA:1.10.8.60 167 242 2.6E-21 T 28-03-2018 CDW54_RS02360 37cc2d40d7727556ffe4ebf33c44c2f8 581 Pfam PF13177 DNA polymerase III, delta subunit 20 178 2.8E-44 T 28-03-2018 CDW54_RS02360 37cc2d40d7727556ffe4ebf33c44c2f8 581 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 41 59 1.5E-5 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CDW54_RS02360 37cc2d40d7727556ffe4ebf33c44c2f8 581 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 124 142 1.5E-5 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CDW54_RS10400 09230ad4b15e89d19da8381ade7b444d 83 Gene3D G3DSA:3.30.300.20 1 79 4.3E-13 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CDW54_RS10400 09230ad4b15e89d19da8381ade7b444d 83 SUPERFAMILY SSF54814 18 61 5.75E-6 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CDW54_RS10400 09230ad4b15e89d19da8381ade7b444d 83 Hamap MF_00088 UPF0109 protein . 4 78 19.681 T 28-03-2018 IPR020627 Uncharacterised protein family UPF0109 CDW54_RS10400 09230ad4b15e89d19da8381ade7b444d 83 Pfam PF13083 KH domain 6 77 2.9E-19 T 28-03-2018 CDW54_RS06985 b95bb28d19b3020ae2aca41380002227 187 SUPERFAMILY SSF116734 20 182 4.09E-32 T 28-03-2018 CDW54_RS06985 b95bb28d19b3020ae2aca41380002227 187 Pfam PF01420 Type I restriction modification DNA specificity domain 37 176 2.2E-13 T 28-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 CDW54_RS06985 b95bb28d19b3020ae2aca41380002227 187 Gene3D G3DSA:3.90.220.20 8 187 7.7E-31 T 28-03-2018 CDW54_RS03500 6440095751cfb23a07d3ecf6aa160064 388 Pfam PF01594 AI-2E family transporter 35 366 1.6E-79 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like CDW54_RS07520 269a6215bdd51c43d364de763d364aa9 418 Gene3D G3DSA:3.10.290.10 315 418 1.6E-21 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDW54_RS07520 269a6215bdd51c43d364de763d364aa9 418 Pfam PF00579 tRNA synthetases class I (W and Y) 28 321 4.2E-81 T 28-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDW54_RS07520 269a6215bdd51c43d364de763d364aa9 418 Gene3D G3DSA:1.10.240.10 222 314 4.5E-37 T 28-03-2018 CDW54_RS07520 269a6215bdd51c43d364de763d364aa9 418 SMART SM00363 350 408 0.0015 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDW54_RS07520 269a6215bdd51c43d364de763d364aa9 418 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 1 416 43.894 T 28-03-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 CDW54_RS07520 269a6215bdd51c43d364de763d364aa9 418 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 39 49 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDW54_RS07520 269a6215bdd51c43d364de763d364aa9 418 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 2 413 2.9E-131 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CDW54_RS07520 269a6215bdd51c43d364de763d364aa9 418 Gene3D G3DSA:3.40.50.620 3 221 5.6E-69 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDW54_RS07520 269a6215bdd51c43d364de763d364aa9 418 SUPERFAMILY SSF52374 1 321 9.65E-106 T 28-03-2018 CDW54_RS07520 269a6215bdd51c43d364de763d364aa9 418 Pfam PF01479 S4 domain 355 396 3.0E-7 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDW54_RS07520 269a6215bdd51c43d364de763d364aa9 418 SUPERFAMILY SSF55174 319 413 1.31E-23 T 28-03-2018 CDW54_RS07520 269a6215bdd51c43d364de763d364aa9 418 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 179 201 3.6E-29 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CDW54_RS07520 269a6215bdd51c43d364de763d364aa9 418 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 43 65 3.6E-29 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CDW54_RS07520 269a6215bdd51c43d364de763d364aa9 418 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 214 226 3.6E-29 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CDW54_RS07520 269a6215bdd51c43d364de763d364aa9 418 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 158 173 3.6E-29 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CDW54_RS05700 ba0ff15ae09b938bbb68caa776bcb7be 99 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 3 99 21.539 T 28-03-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 CDW54_RS05700 ba0ff15ae09b938bbb68caa776bcb7be 99 TIGRFAM TIGR00166 S6: ribosomal protein bS6 5 98 1.7E-26 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS05700 ba0ff15ae09b938bbb68caa776bcb7be 99 Gene3D G3DSA:3.30.70.60 4 99 2.0E-29 T 28-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 CDW54_RS05700 ba0ff15ae09b938bbb68caa776bcb7be 99 SUPERFAMILY SSF54995 5 98 2.22E-29 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS05700 ba0ff15ae09b938bbb68caa776bcb7be 99 Pfam PF01250 Ribosomal protein S6 5 96 1.6E-27 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS08880 702401f906ed9710e48770ca37281607 279 Gene3D G3DSA:3.40.190.10 131 273 5.5E-51 T 28-03-2018 CDW54_RS08880 702401f906ed9710e48770ca37281607 279 Pfam PF03180 NLPA lipoprotein 36 273 9.2E-88 T 28-03-2018 IPR004872 Lipoprotein NlpA family CDW54_RS08880 702401f906ed9710e48770ca37281607 279 PIRSF PIRSF002854 1 274 6.9E-93 T 28-03-2018 IPR004872 Lipoprotein NlpA family CDW54_RS08880 702401f906ed9710e48770ca37281607 279 Gene3D G3DSA:3.40.190.10 35 130 7.5E-19 T 28-03-2018 CDW54_RS08880 702401f906ed9710e48770ca37281607 279 SUPERFAMILY SSF53850 35 273 2.47E-84 T 28-03-2018 CDW54_RS03790 08f90bf528eb59cf43441d3bced6f4de 321 PIRSF PIRSF000355 1 315 4.5E-75 T 28-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CDW54_RS03790 08f90bf528eb59cf43441d3bced6f4de 321 Pfam PF00268 Ribonucleotide reductase, small chain 9 279 1.2E-88 T 28-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CDW54_RS03790 08f90bf528eb59cf43441d3bced6f4de 321 TIGRFAM TIGR04171 RNR_1b_NrdF: ribonucleoside-diphosphate reductase, class 1b, beta subunit 6 317 1.4E-151 T 28-03-2018 IPR026494 Ribonucleoside reductase subunit beta, NrdF GO:0005971|GO:0009263 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CDW54_RS03790 08f90bf528eb59cf43441d3bced6f4de 321 Gene3D G3DSA:1.10.620.20 4 292 2.0E-79 T 28-03-2018 CDW54_RS03790 08f90bf528eb59cf43441d3bced6f4de 321 SUPERFAMILY SSF47240 4 316 1.7E-101 T 28-03-2018 IPR009078 Ferritin-like superfamily CDW54_RS10300 feb6be4a018688ef59f7eb476bef2827 88 Gene3D G3DSA:1.10.443.10 14 82 4.8E-10 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CDW54_RS10300 feb6be4a018688ef59f7eb476bef2827 88 Pfam PF00589 Phage integrase family 31 64 1.1E-6 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CDW54_RS10300 feb6be4a018688ef59f7eb476bef2827 88 SUPERFAMILY SSF56349 34 75 2.35E-10 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CDW54_RS10090 b9e256d4cc10e80b31d52614e9e615a3 127 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 48 122 4.2E-8 T 28-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CDW54_RS00300 4a1669fdf04009ff935348e40a659be3 91 ProDom PD062738 UPF0223 FAMILY UNCHARACTERISED CYTOSOLIC SUPERFAMILY YKTA LMO1058/LIN1050 INOSITOL MW0980 M6_SPY0948 4 89 2.0E-31 T 28-03-2018 IPR007920 Protein of unknown function UPF0223 CDW54_RS00300 4a1669fdf04009ff935348e40a659be3 91 SUPERFAMILY SSF158504 5 88 4.45E-32 T 28-03-2018 IPR023324 BH2638-like domain CDW54_RS00300 4a1669fdf04009ff935348e40a659be3 91 Pfam PF05256 Uncharacterised protein family (UPF0223) 3 87 8.6E-36 T 28-03-2018 IPR007920 Protein of unknown function UPF0223 CDW54_RS00300 4a1669fdf04009ff935348e40a659be3 91 Gene3D G3DSA:1.10.220.80 13 89 3.7E-30 T 28-03-2018 IPR023324 BH2638-like domain CDW54_RS00300 4a1669fdf04009ff935348e40a659be3 91 PIRSF PIRSF037260 1 91 3.9E-37 T 28-03-2018 IPR007920 Protein of unknown function UPF0223 CDW54_RS00300 4a1669fdf04009ff935348e40a659be3 91 Hamap MF_01041 UPF0223 protein . 2 89 24.027 T 28-03-2018 IPR007920 Protein of unknown function UPF0223 CDW54_RS05720 cdce20e3301075a2fc91692e25d6a272 150 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 150 25.505 T 28-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS05720 cdce20e3301075a2fc91692e25d6a272 150 Gene3D G3DSA:3.40.5.10 1 49 3.6E-22 T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS05720 cdce20e3301075a2fc91692e25d6a272 150 Pfam PF03948 Ribosomal protein L9, C-terminal domain 63 148 7.5E-30 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal CDW54_RS05720 cdce20e3301075a2fc91692e25d6a272 150 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 150 1.1E-45 T 28-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS05720 cdce20e3301075a2fc91692e25d6a272 150 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 47 7.2E-22 T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS05720 cdce20e3301075a2fc91692e25d6a272 150 SUPERFAMILY SSF55653 57 149 5.1E-28 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal CDW54_RS05720 cdce20e3301075a2fc91692e25d6a272 150 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS05720 cdce20e3301075a2fc91692e25d6a272 150 SUPERFAMILY SSF55658 1 56 6.98E-17 T 28-03-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal CDW54_RS05720 cdce20e3301075a2fc91692e25d6a272 150 Gene3D G3DSA:3.10.430.100 63 149 7.7E-30 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal CDW54_RS11965 db33aaa2d276acf3ba3cf59be2a61ea1 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 51 67 2.2E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDW54_RS11965 db33aaa2d276acf3ba3cf59be2a61ea1 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 2.2E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDW54_RS11965 db33aaa2d276acf3ba3cf59be2a61ea1 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 2.2E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDW54_RS11965 db33aaa2d276acf3ba3cf59be2a61ea1 146 SUPERFAMILY SSF46785 3 141 6.94E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS11965 db33aaa2d276acf3ba3cf59be2a61ea1 146 Gene3D G3DSA:1.10.10.10 6 146 1.0E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS11965 db33aaa2d276acf3ba3cf59be2a61ea1 146 Pfam PF01047 MarR family 34 92 2.5E-15 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDW54_RS11965 db33aaa2d276acf3ba3cf59be2a61ea1 146 SMART SM00347 27 122 9.6E-22 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDW54_RS10940 f1ab43b434afdb569e84a9e5b200b538 336 Pfam PF02016 LD-carboxypeptidase 13 322 4.4E-72 T 28-03-2018 IPR003507 Peptidase family S66 CDW54_RS10940 f1ab43b434afdb569e84a9e5b200b538 336 PIRSF PIRSF028757 1 336 4.0E-65 T 28-03-2018 IPR003507 Peptidase family S66 CDW54_RS10940 f1ab43b434afdb569e84a9e5b200b538 336 Gene3D G3DSA:3.50.30.60 163 335 7.0E-41 T 28-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain CDW54_RS10940 f1ab43b434afdb569e84a9e5b200b538 336 SUPERFAMILY SSF141986 180 326 1.57E-26 T 28-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain CDW54_RS10940 f1ab43b434afdb569e84a9e5b200b538 336 Gene3D G3DSA:3.40.50.10740 1 162 4.1E-40 T 28-03-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal domain CDW54_RS10940 f1ab43b434afdb569e84a9e5b200b538 336 SUPERFAMILY SSF52317 1 162 5.04E-39 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CDW54_RS09280 1f30a31ee2e398e188b7a2f62daa59e9 151 Gene3D G3DSA:3.40.630.30 1 141 2.1E-19 T 28-03-2018 CDW54_RS09280 1f30a31ee2e398e188b7a2f62daa59e9 151 SUPERFAMILY SSF55729 1 145 5.23E-19 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDW54_RS09280 1f30a31ee2e398e188b7a2f62daa59e9 151 Pfam PF13673 Acetyltransferase (GNAT) domain 30 142 3.5E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CDW54_RS04105 35c462e23169616d960baaf8e0174bbf 428 Gene3D G3DSA:1.10.8.60 139 228 1.1E-18 T 28-03-2018 CDW54_RS04105 35c462e23169616d960baaf8e0174bbf 428 SMART SM00382 38 150 3.1E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS04105 35c462e23169616d960baaf8e0174bbf 428 Pfam PF16193 AAA C-terminal domain 172 252 2.9E-26 T 28-03-2018 IPR032423 AAA C-terminal domain CDW54_RS04105 35c462e23169616d960baaf8e0174bbf 428 SUPERFAMILY SSF52540 3 233 1.49E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS04105 35c462e23169616d960baaf8e0174bbf 428 SUPERFAMILY SSF48019 238 423 2.32E-71 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CDW54_RS04105 35c462e23169616d960baaf8e0174bbf 428 Gene3D G3DSA:3.40.50.300 1 138 1.2E-28 T 28-03-2018 CDW54_RS04105 35c462e23169616d960baaf8e0174bbf 428 Gene3D G3DSA:1.20.272.10 237 330 2.6E-34 T 28-03-2018 CDW54_RS04105 35c462e23169616d960baaf8e0174bbf 428 Gene3D G3DSA:1.10.3710.10 333 428 3.4E-33 T 28-03-2018 CDW54_RS04105 35c462e23169616d960baaf8e0174bbf 428 Pfam PF12002 MgsA AAA+ ATPase C terminal 253 418 2.1E-64 T 28-03-2018 IPR021886 MgsA AAA+ ATPase C-terminal CDW54_RS04105 35c462e23169616d960baaf8e0174bbf 428 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 42 144 1.0E-15 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CDW54_RS09375 084ee3bf3b735425b05c11b718ea2633 145 Pfam PF05164 Cell division protein ZapA 12 89 3.3E-7 T 28-03-2018 IPR007838 Cell division protein ZapA-like CDW54_RS09375 084ee3bf3b735425b05c11b718ea2633 145 SUPERFAMILY SSF102829 9 92 2.35E-14 T 28-03-2018 IPR007838 Cell division protein ZapA-like CDW54_RS12120 a88bdeb40f37852174a991df174db039 282 Gene3D G3DSA:3.40.50.10170 1 152 1.3E-42 T 28-03-2018 CDW54_RS12120 a88bdeb40f37852174a991df174db039 282 Pfam PF02645 Uncharacterised protein, DegV family COG1307 2 281 1.0E-86 T 28-03-2018 IPR003797 DegV CDW54_RS12120 a88bdeb40f37852174a991df174db039 282 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 4 279 2.8E-95 T 28-03-2018 IPR003797 DegV CDW54_RS12120 a88bdeb40f37852174a991df174db039 282 SUPERFAMILY SSF82549 1 280 3.14E-91 T 28-03-2018 CDW54_RS12120 a88bdeb40f37852174a991df174db039 282 Gene3D G3DSA:3.30.1180.10 154 281 5.0E-38 T 28-03-2018 CDW54_RS01725 cbda0db5ca2ca75b8f05ba48db2e117c 304 Pfam PF01545 Cation efflux family 20 207 1.8E-46 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CDW54_RS01725 cbda0db5ca2ca75b8f05ba48db2e117c 304 SUPERFAMILY SSF160240 211 286 6.67E-11 T 28-03-2018 CDW54_RS01725 cbda0db5ca2ca75b8f05ba48db2e117c 304 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 14 288 5.5E-80 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CDW54_RS01725 cbda0db5ca2ca75b8f05ba48db2e117c 304 Gene3D G3DSA:3.30.70.1350 209 290 7.3E-13 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CDW54_RS01725 cbda0db5ca2ca75b8f05ba48db2e117c 304 SUPERFAMILY SSF161111 11 209 5.75E-54 T 28-03-2018 CDW54_RS01725 cbda0db5ca2ca75b8f05ba48db2e117c 304 Gene3D G3DSA:1.20.1510.10 12 208 2.7E-55 T 28-03-2018 CDW54_RS12390 b9151b0c969502928762718960a44180 427 Pfam PF00860 Permease family 25 391 1.1E-96 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CDW54_RS12390 b9151b0c969502928762718960a44180 427 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 20 417 1.1E-133 T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CDW54_RS07330 8ba72d5de0267ff11ebc14932c225cbf 498 SUPERFAMILY SSF51445 6 493 5.36E-141 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CDW54_RS07330 8ba72d5de0267ff11ebc14932c225cbf 498 Pfam PF00232 Glycosyl hydrolase family 1 3 488 3.0E-122 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS07330 8ba72d5de0267ff11ebc14932c225cbf 498 Gene3D G3DSA:3.20.20.80 4 496 3.3E-136 T 28-03-2018 CDW54_RS07330 8ba72d5de0267ff11ebc14932c225cbf 498 PRINTS PR00131 Glycosyl hydrolase family 1 signature 407 418 2.7E-13 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS07330 8ba72d5de0267ff11ebc14932c225cbf 498 PRINTS PR00131 Glycosyl hydrolase family 1 signature 386 394 2.7E-13 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS07330 8ba72d5de0267ff11ebc14932c225cbf 498 PRINTS PR00131 Glycosyl hydrolase family 1 signature 453 465 2.7E-13 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS07330 8ba72d5de0267ff11ebc14932c225cbf 498 PRINTS PR00131 Glycosyl hydrolase family 1 signature 319 333 2.7E-13 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS07330 8ba72d5de0267ff11ebc14932c225cbf 498 PRINTS PR00131 Glycosyl hydrolase family 1 signature 428 445 2.7E-13 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS07330 8ba72d5de0267ff11ebc14932c225cbf 498 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 10 24 - T 28-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site CDW54_RS07330 8ba72d5de0267ff11ebc14932c225cbf 498 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 386 394 - T 28-03-2018 IPR018120 Glycoside hydrolase family 1, active site CDW54_RS12190 26ac11f59a8f408e0b83a977a9ce7129 228 Gene3D G3DSA:3.40.50.300 1 228 2.9E-61 T 28-03-2018 CDW54_RS12190 26ac11f59a8f408e0b83a977a9ce7129 228 Pfam PF00005 ABC transporter 24 171 2.9E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS12190 26ac11f59a8f408e0b83a977a9ce7129 228 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS12190 26ac11f59a8f408e0b83a977a9ce7129 228 SUPERFAMILY SSF52540 4 225 2.46E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS12190 26ac11f59a8f408e0b83a977a9ce7129 228 SMART SM00382 33 222 1.9E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS02915 16222d4f3d4beacda3d425e6963f55b4 194 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 17 191 1.5E-51 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CDW54_RS02915 16222d4f3d4beacda3d425e6963f55b4 194 PIRSF PIRSF001467 8 126 3.6E-45 T 28-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 CDW54_RS02915 16222d4f3d4beacda3d425e6963f55b4 194 PIRSF PIRSF001467 143 194 9.2E-11 T 28-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 CDW54_RS02915 16222d4f3d4beacda3d425e6963f55b4 194 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 50 67 - T 28-03-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 CDW54_RS02915 16222d4f3d4beacda3d425e6963f55b4 194 SUPERFAMILY SSF50891 15 116 1.61E-62 T 28-03-2018 IPR029000 Cyclophilin-like domain CDW54_RS02915 16222d4f3d4beacda3d425e6963f55b4 194 SUPERFAMILY SSF50891 144 192 1.61E-62 T 28-03-2018 IPR029000 Cyclophilin-like domain CDW54_RS02915 16222d4f3d4beacda3d425e6963f55b4 194 Gene3D G3DSA:2.40.100.10 4 194 9.6E-70 T 28-03-2018 IPR029000 Cyclophilin-like domain CDW54_RS02915 16222d4f3d4beacda3d425e6963f55b4 194 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 55 67 7.3E-21 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CDW54_RS02915 16222d4f3d4beacda3d425e6963f55b4 194 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 29 44 7.3E-21 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CDW54_RS02915 16222d4f3d4beacda3d425e6963f55b4 194 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 97 112 7.3E-21 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CDW54_RS01585 80c7fee5950040a00e1677e60bf13f2e 76 PIRSF PIRSF037356 1 76 6.5E-33 T 28-03-2018 IPR014904 Protein of unknown function DUF1797 CDW54_RS01585 80c7fee5950040a00e1677e60bf13f2e 76 Pfam PF08796 Protein of unknown function (DUF1797) 9 75 1.1E-31 T 28-03-2018 IPR014904 Protein of unknown function DUF1797 CDW54_RS01585 80c7fee5950040a00e1677e60bf13f2e 76 SUPERFAMILY SSF143567 4 76 5.36E-28 T 28-03-2018 CDW54_RS11770 ac3f16991fa9f1b3839260625aa23bd0 116 Gene3D G3DSA:2.60.300.12 1 113 5.7E-22 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CDW54_RS11770 ac3f16991fa9f1b3839260625aa23bd0 116 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 111 4.7E-21 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CDW54_RS11770 ac3f16991fa9f1b3839260625aa23bd0 116 SUPERFAMILY SSF89360 1 112 3.22E-19 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CDW54_RS00910 4328aa59060cfe725c5941e2d53d3344 91 SMART SM00411 2 91 7.7E-53 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CDW54_RS00910 4328aa59060cfe725c5941e2d53d3344 91 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 2.1E-22 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CDW54_RS00910 4328aa59060cfe725c5941e2d53d3344 91 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 2.1E-22 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CDW54_RS00910 4328aa59060cfe725c5941e2d53d3344 91 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 2.1E-22 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CDW54_RS00910 4328aa59060cfe725c5941e2d53d3344 91 SUPERFAMILY SSF47729 3 91 1.05E-35 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CDW54_RS00910 4328aa59060cfe725c5941e2d53d3344 91 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 47 66 - T 28-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 CDW54_RS00910 4328aa59060cfe725c5941e2d53d3344 91 Pfam PF00216 Bacterial DNA-binding protein 3 91 6.6E-38 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CDW54_RS00910 4328aa59060cfe725c5941e2d53d3344 91 Gene3D G3DSA:4.10.520.10 2 91 4.9E-39 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CDW54_RS10715 a6851bb874aa3115f819245f08728446 320 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 6 316 4.3E-103 T 28-03-2018 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 CDW54_RS10715 a6851bb874aa3115f819245f08728446 320 Gene3D G3DSA:3.30.420.40 124 320 5.4E-63 T 28-03-2018 CDW54_RS10715 a6851bb874aa3115f819245f08728446 320 SUPERFAMILY SSF53067 4 318 7.6E-72 T 28-03-2018 CDW54_RS10715 a6851bb874aa3115f819245f08728446 320 ProSitePatterns PS01125 ROK family signature. 139 166 - T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CDW54_RS10715 a6851bb874aa3115f819245f08728446 320 Pfam PF00480 ROK family 6 317 1.1E-72 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CDW54_RS10715 a6851bb874aa3115f819245f08728446 320 Gene3D G3DSA:3.30.420.40 2 123 2.1E-25 T 28-03-2018 CDW54_RS00060 9ee98fd4fb2df704ac6c5b15df734048 198 Gene3D G3DSA:3.40.109.10 2 197 3.5E-26 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CDW54_RS00060 9ee98fd4fb2df704ac6c5b15df734048 198 SUPERFAMILY SSF55469 4 198 2.22E-70 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CDW54_RS00060 9ee98fd4fb2df704ac6c5b15df734048 198 Pfam PF00881 Nitroreductase family 9 176 1.0E-16 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CDW54_RS02590 c918f8349b62162b66682fb1bac519b5 573 Gene3D G3DSA:1.10.287.1060 460 557 0.081 T 28-03-2018 CDW54_RS02590 c918f8349b62162b66682fb1bac519b5 573 Gene3D G3DSA:3.90.20.10 28 200 0.0033 T 28-03-2018 CDW54_RS02590 c918f8349b62162b66682fb1bac519b5 573 Hamap MF_00728 Septation ring formation regulator EzrA [ezrA]. 7 569 23.674 T 28-03-2018 IPR010379 Septation ring formation regulator EzrA GO:0000921|GO:0005940|GO:0016021 CDW54_RS02590 c918f8349b62162b66682fb1bac519b5 573 Pfam PF06160 Septation ring formation regulator, EzrA 9 566 1.2E-187 T 28-03-2018 IPR010379 Septation ring formation regulator EzrA GO:0000921|GO:0005940|GO:0016021 CDW54_RS02590 c918f8349b62162b66682fb1bac519b5 573 Gene3D G3DSA:1.20.120.570 201 436 0.13 T 28-03-2018 CDW54_RS00475 957d396089438b1a9d23683bf52ba0c3 295 Gene3D G3DSA:1.10.3720.10 63 294 7.4E-45 T 28-03-2018 CDW54_RS00475 957d396089438b1a9d23683bf52ba0c3 295 Gene3D G3DSA:1.20.58.370 7 48 2.5E-7 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CDW54_RS00475 957d396089438b1a9d23683bf52ba0c3 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 284 1.2E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS00475 957d396089438b1a9d23683bf52ba0c3 295 SUPERFAMILY SSF161098 58 284 2.09E-59 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS01670 b36c6e2ac89046c38f2acb0dddcbd5bb 177 SUPERFAMILY SSF159234 3 170 1.44E-34 T 28-03-2018 IPR007295 Domain of unknown function DUF402 CDW54_RS01670 b36c6e2ac89046c38f2acb0dddcbd5bb 177 Gene3D G3DSA:2.40.380.10 14 170 7.7E-33 T 28-03-2018 IPR007295 Domain of unknown function DUF402 CDW54_RS01670 b36c6e2ac89046c38f2acb0dddcbd5bb 177 Pfam PF04167 Protein of unknown function (DUF402) 60 124 5.4E-17 T 28-03-2018 IPR007295 Domain of unknown function DUF402 CDW54_RS01670 b36c6e2ac89046c38f2acb0dddcbd5bb 177 PIRSF PIRSF028345 1 177 1.9E-77 T 28-03-2018 IPR016882 Uncharacterised protein family UPF0374 CDW54_RS01670 b36c6e2ac89046c38f2acb0dddcbd5bb 177 Hamap MF_01568 UPF0374 protein . 1 175 48.965 T 28-03-2018 IPR016882 Uncharacterised protein family UPF0374 CDW54_RS06735 32479724a11bad4d09885c325791f764 325 SUPERFAMILY SSF54211 1 167 2.13E-41 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CDW54_RS06735 32479724a11bad4d09885c325791f764 325 PIRSF PIRSF015950 1 325 2.5E-127 T 28-03-2018 IPR005935 Diphosphomevalonate/phosphomevalonate decarboxylase GO:0008299|GO:0016831 KEGG: 00900+4.1.1.33|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168|Reactome: R-HSA-446199 CDW54_RS06735 32479724a11bad4d09885c325791f764 325 SUPERFAMILY SSF55060 175 321 3.6E-47 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CDW54_RS06735 32479724a11bad4d09885c325791f764 325 Gene3D G3DSA:3.30.70.890 172 319 9.3E-47 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CDW54_RS06735 32479724a11bad4d09885c325791f764 325 Gene3D G3DSA:3.30.230.10 2 171 6.3E-58 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CDW54_RS06735 32479724a11bad4d09885c325791f764 325 TIGRFAM TIGR01240 mevDPdecarb: diphosphomevalonate decarboxylase 5 308 1.0E-160 T 28-03-2018 IPR029765 Diphosphomevalonate decarboxylase GO:0004163|GO:0005829|GO:0019287 KEGG: 00900+4.1.1.33|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168|Reactome: R-HSA-446199 CDW54_RS12460 aa66848d9bbf2a7c065648cd595c8b67 143 Gene3D G3DSA:3.40.630.30 3 142 2.4E-28 T 28-03-2018 CDW54_RS12460 aa66848d9bbf2a7c065648cd595c8b67 143 SUPERFAMILY SSF55729 11 142 3.16E-31 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDW54_RS12460 aa66848d9bbf2a7c065648cd595c8b67 143 Pfam PF13673 Acetyltransferase (GNAT) domain 41 142 1.9E-17 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CDW54_RS06930 6d901941112161842bfd7aeb9f81a588 211 Pfam PF06197 Protein of unknown function (DUF998) 14 204 5.8E-14 T 28-03-2018 IPR009339 Protein of unknown function DUF998 CDW54_RS06930 6d901941112161842bfd7aeb9f81a588 211 Gene3D G3DSA:1.20.5.930 117 192 0.0089 T 28-03-2018 CDW54_RS11185 77470efb6e6e1a39d8c671675dd9478b 678 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 407 433 3.2E-11 T 28-03-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 CDW54_RS11185 77470efb6e6e1a39d8c671675dd9478b 678 Gene3D G3DSA:3.30.1490.70 221 321 1.2E-25 T 28-03-2018 CDW54_RS11185 77470efb6e6e1a39d8c671675dd9478b 678 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 119 148 - T 28-03-2018 IPR018239 NAD-dependent DNA ligase, active site CDW54_RS11185 77470efb6e6e1a39d8c671675dd9478b 678 Pfam PF14520 Helix-hairpin-helix domain 447 498 2.4E-4 T 28-03-2018 CDW54_RS11185 77470efb6e6e1a39d8c671675dd9478b 678 SUPERFAMILY SSF56091 8 318 1.26E-121 T 28-03-2018 CDW54_RS11185 77470efb6e6e1a39d8c671675dd9478b 678 Gene3D G3DSA:3.40.50.10190 571 674 3.9E-24 T 28-03-2018 IPR001357 BRCT domain CDW54_RS11185 77470efb6e6e1a39d8c671675dd9478b 678 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 17 666 6.1E-261 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CDW54_RS11185 77470efb6e6e1a39d8c671675dd9478b 678 Gene3D G3DSA:1.10.287.610 1 73 2.6E-24 T 28-03-2018 CDW54_RS11185 77470efb6e6e1a39d8c671675dd9478b 678 Pfam PF12826 Helix-hairpin-helix motif 509 571 8.6E-23 T 28-03-2018 CDW54_RS11185 77470efb6e6e1a39d8c671675dd9478b 678 PIRSF PIRSF001604 1 675 3.2E-255 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CDW54_RS11185 77470efb6e6e1a39d8c671675dd9478b 678 Gene3D G3DSA:2.40.50.140 322 390 3.2E-30 T 28-03-2018 CDW54_RS11185 77470efb6e6e1a39d8c671675dd9478b 678 SUPERFAMILY SSF47781 404 584 5.93E-62 T 28-03-2018 IPR010994 RuvA domain 2-like CDW54_RS11185 77470efb6e6e1a39d8c671675dd9478b 678 Gene3D G3DSA:3.30.1490.70 87 173 2.7E-22 T 28-03-2018 CDW54_RS11185 77470efb6e6e1a39d8c671675dd9478b 678 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 9 318 2.8E-125 T 28-03-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 CDW54_RS11185 77470efb6e6e1a39d8c671675dd9478b 678 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 596 667 2.8E-16 T 28-03-2018 IPR001357 BRCT domain CDW54_RS11185 77470efb6e6e1a39d8c671675dd9478b 678 Gene3D G3DSA:1.10.150.20 506 570 3.7E-21 T 28-03-2018 CDW54_RS11185 77470efb6e6e1a39d8c671675dd9478b 678 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 331 346 - T 28-03-2018 IPR033136 NAD-dependent DNA ligase, conserved site CDW54_RS11185 77470efb6e6e1a39d8c671675dd9478b 678 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 322 398 1.8E-32 T 28-03-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 CDW54_RS11185 77470efb6e6e1a39d8c671675dd9478b 678 SUPERFAMILY SSF50249 318 399 1.4E-26 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDW54_RS11185 77470efb6e6e1a39d8c671675dd9478b 678 SUPERFAMILY SSF52113 597 672 4.42E-20 T 28-03-2018 IPR001357 BRCT domain CDW54_RS11185 77470efb6e6e1a39d8c671675dd9478b 678 Hamap MF_01588 DNA ligase [ligA]. 8 670 51.489 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CDW54_RS11185 77470efb6e6e1a39d8c671675dd9478b 678 SMART SM00532 9 447 5.7E-264 T 28-03-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 CDW54_RS11185 77470efb6e6e1a39d8c671675dd9478b 678 Gene3D G3DSA:1.10.150.20 431 504 6.4E-26 T 28-03-2018 CDW54_RS11185 77470efb6e6e1a39d8c671675dd9478b 678 SMART SM00292 596 673 7.5E-16 T 28-03-2018 IPR001357 BRCT domain CDW54_RS05830 91ed4209b3edf25dd3e01b469c1c105f 220 Pfam PF01791 DeoC/LacD family aldolase 7 211 1.6E-21 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CDW54_RS05830 91ed4209b3edf25dd3e01b469c1c105f 220 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 1 216 37.187 T 28-03-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 CDW54_RS05830 91ed4209b3edf25dd3e01b469c1c105f 220 PIRSF PIRSF001357 1 219 9.8E-79 T 28-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CDW54_RS05830 91ed4209b3edf25dd3e01b469c1c105f 220 Gene3D G3DSA:3.20.20.70 1 217 6.5E-97 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDW54_RS05830 91ed4209b3edf25dd3e01b469c1c105f 220 SUPERFAMILY SSF51569 1 214 5.44E-84 T 28-03-2018 CDW54_RS05830 91ed4209b3edf25dd3e01b469c1c105f 220 SMART SM01133 2 214 1.4E-106 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CDW54_RS05830 91ed4209b3edf25dd3e01b469c1c105f 220 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 2 212 5.5E-90 T 28-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CDW54_RS10285 6be2c7981890469f83ae4efe70669eb6 282 SUPERFAMILY SSF52540 4 253 7.09E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS10285 6be2c7981890469f83ae4efe70669eb6 282 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 10 140 1.4E-62 T 28-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 CDW54_RS10285 6be2c7981890469f83ae4efe70669eb6 282 Gene3D G3DSA:3.40.50.300 1 157 9.7E-24 T 28-03-2018 CDW54_RS10285 6be2c7981890469f83ae4efe70669eb6 282 Gene3D G3DSA:1.10.8.300 170 277 7.5E-28 T 28-03-2018 CDW54_RS10285 6be2c7981890469f83ae4efe70669eb6 282 PIRSF PIRSF002849 1 282 7.1E-118 T 28-03-2018 CDW54_RS01750 66913633bc66ff0a034cea36f61fca00 210 Pfam PF00072 Response regulator receiver domain 4 115 2.9E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDW54_RS01750 66913633bc66ff0a034cea36f61fca00 210 SMART SM00421 146 203 4.3E-26 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDW54_RS01750 66913633bc66ff0a034cea36f61fca00 210 SMART SM00448 2 115 5.7E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDW54_RS01750 66913633bc66ff0a034cea36f61fca00 210 SUPERFAMILY SSF52172 1 134 3.27E-33 T 28-03-2018 IPR011006 CheY-like superfamily CDW54_RS01750 66913633bc66ff0a034cea36f61fca00 210 Gene3D G3DSA:1.10.10.10 127 210 2.6E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS01750 66913633bc66ff0a034cea36f61fca00 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 203 6.2E-21 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDW54_RS01750 66913633bc66ff0a034cea36f61fca00 210 Gene3D G3DSA:3.40.50.2300 1 126 1.4E-32 T 28-03-2018 CDW54_RS01750 66913633bc66ff0a034cea36f61fca00 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 7.2E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDW54_RS01750 66913633bc66ff0a034cea36f61fca00 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 7.2E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDW54_RS01750 66913633bc66ff0a034cea36f61fca00 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 7.2E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDW54_RS01750 66913633bc66ff0a034cea36f61fca00 210 ProSitePatterns PS00622 LuxR-type HTH domain signature. 163 190 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDW54_RS01750 66913633bc66ff0a034cea36f61fca00 210 SUPERFAMILY SSF46894 139 209 1.39E-23 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDW54_RS01680 9d802f877468e0364f7fd4298b1f932b 265 Pfam PF02631 RecX family 82 202 1.3E-28 T 28-03-2018 IPR003783 Regulatory protein RecX GO:0006282 CDW54_RS01680 9d802f877468e0364f7fd4298b1f932b 265 Gene3D G3DSA:1.10.10.10 216 263 8.3E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS01680 9d802f877468e0364f7fd4298b1f932b 265 Gene3D G3DSA:1.10.10.10 106 151 3.6E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS01680 9d802f877468e0364f7fd4298b1f932b 265 Gene3D G3DSA:1.10.10.10 41 105 1.3E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS01680 9d802f877468e0364f7fd4298b1f932b 265 Hamap MF_01114 Regulatory protein RecX [recX]. 40 207 16.611 T 28-03-2018 IPR003783 Regulatory protein RecX GO:0006282 CDW54_RS01680 9d802f877468e0364f7fd4298b1f932b 265 Gene3D G3DSA:1.10.10.10 154 204 7.3E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS10010 afe6616df22be5333006d24b56e43406 299 TIGRFAM TIGR00436 era: GTP-binding protein Era 7 277 6.9E-109 T 28-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS10010 afe6616df22be5333006d24b56e43406 299 Hamap MF_00367 GTPase Era [era]. 4 294 39.381 T 28-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS10010 afe6616df22be5333006d24b56e43406 299 Pfam PF01926 50S ribosome-binding GTPase 9 123 1.3E-24 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CDW54_RS10010 afe6616df22be5333006d24b56e43406 299 SUPERFAMILY SSF54814 179 295 8.37E-46 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CDW54_RS10010 afe6616df22be5333006d24b56e43406 299 Gene3D G3DSA:3.30.300.20 196 297 4.0E-49 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CDW54_RS10010 afe6616df22be5333006d24b56e43406 299 Gene3D G3DSA:3.40.50.300 8 195 2.3E-35 T 28-03-2018 CDW54_RS10010 afe6616df22be5333006d24b56e43406 299 SUPERFAMILY SSF52540 9 203 3.21E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS10010 afe6616df22be5333006d24b56e43406 299 Pfam PF07650 KH domain 206 283 6.8E-24 T 28-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS10010 afe6616df22be5333006d24b56e43406 299 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 6 166 1.1E-29 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CDW54_RS10350 ce6c488cd55ea97f1dd9e7c14f4bec3f 824 SUPERFAMILY SSF56784 319 339 3.86E-40 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS10350 ce6c488cd55ea97f1dd9e7c14f4bec3f 824 SUPERFAMILY SSF56784 421 661 3.86E-40 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS10350 ce6c488cd55ea97f1dd9e7c14f4bec3f 824 Gene3D G3DSA:3.40.1110.10 271 460 4.4E-24 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CDW54_RS10350 ce6c488cd55ea97f1dd9e7c14f4bec3f 824 Gene3D G3DSA:2.70.150.10 22 218 2.4E-32 T 28-03-2018 CDW54_RS10350 ce6c488cd55ea97f1dd9e7c14f4bec3f 824 SUPERFAMILY SSF81665 21 123 6.93E-60 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CDW54_RS10350 ce6c488cd55ea97f1dd9e7c14f4bec3f 824 SUPERFAMILY SSF81665 221 315 6.93E-60 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CDW54_RS10350 ce6c488cd55ea97f1dd9e7c14f4bec3f 824 SUPERFAMILY SSF81665 608 779 6.93E-60 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CDW54_RS10350 ce6c488cd55ea97f1dd9e7c14f4bec3f 824 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 559 575 2.6E-6 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDW54_RS10350 ce6c488cd55ea97f1dd9e7c14f4bec3f 824 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 590 615 2.6E-6 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDW54_RS10350 ce6c488cd55ea97f1dd9e7c14f4bec3f 824 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 424 442 2.6E-6 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDW54_RS10350 ce6c488cd55ea97f1dd9e7c14f4bec3f 824 Pfam PF00122 E1-E2 ATPase 121 301 2.0E-44 T 28-03-2018 CDW54_RS10350 ce6c488cd55ea97f1dd9e7c14f4bec3f 824 Pfam PF00702 haloacid dehalogenase-like hydrolase 317 573 2.3E-24 T 28-03-2018 CDW54_RS10350 ce6c488cd55ea97f1dd9e7c14f4bec3f 824 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 323 329 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CDW54_RS10350 ce6c488cd55ea97f1dd9e7c14f4bec3f 824 Gene3D G3DSA:1.20.1110.10 522 809 1.3E-42 T 28-03-2018 CDW54_RS10350 ce6c488cd55ea97f1dd9e7c14f4bec3f 824 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 95 346 1.3E-37 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDW54_RS10350 ce6c488cd55ea97f1dd9e7c14f4bec3f 824 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 529 644 7.5E-25 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDW54_RS10350 ce6c488cd55ea97f1dd9e7c14f4bec3f 824 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 559 578 1.5E-22 T 28-03-2018 CDW54_RS10350 ce6c488cd55ea97f1dd9e7c14f4bec3f 824 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 169 183 1.5E-22 T 28-03-2018 CDW54_RS10350 ce6c488cd55ea97f1dd9e7c14f4bec3f 824 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 483 493 1.5E-22 T 28-03-2018 CDW54_RS10350 ce6c488cd55ea97f1dd9e7c14f4bec3f 824 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 321 335 1.5E-22 T 28-03-2018 CDW54_RS10350 ce6c488cd55ea97f1dd9e7c14f4bec3f 824 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 461 472 1.5E-22 T 28-03-2018 CDW54_RS10350 ce6c488cd55ea97f1dd9e7c14f4bec3f 824 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 582 594 1.5E-22 T 28-03-2018 CDW54_RS10350 ce6c488cd55ea97f1dd9e7c14f4bec3f 824 SUPERFAMILY SSF81653 124 215 4.45E-23 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CDW54_RS01570 018bf7a27360a4b8935f09d2d5c37a6c 320 SUPERFAMILY SSF53901 7 319 4.24E-54 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDW54_RS01570 018bf7a27360a4b8935f09d2d5c37a6c 320 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 3 320 63.568 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CDW54_RS01570 018bf7a27360a4b8935f09d2d5c37a6c 320 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 107 183 6.0E-28 T 28-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CDW54_RS01570 018bf7a27360a4b8935f09d2d5c37a6c 320 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 7 318 2.3E-104 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CDW54_RS01570 018bf7a27360a4b8935f09d2d5c37a6c 320 Gene3D G3DSA:3.40.47.10 161 320 4.1E-38 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDW54_RS01570 018bf7a27360a4b8935f09d2d5c37a6c 320 Gene3D G3DSA:3.40.47.10 6 160 1.0E-30 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDW54_RS01570 018bf7a27360a4b8935f09d2d5c37a6c 320 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 234 319 6.7E-30 T 28-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CDW54_RS03730 ce9374a68172e7c793f5b314b1cf4db8 339 SMART SM00644 36 174 2.6E-28 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CDW54_RS03730 ce9374a68172e7c793f5b314b1cf4db8 339 Gene3D G3DSA:3.40.80.10 26 208 6.0E-21 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CDW54_RS03730 ce9374a68172e7c793f5b314b1cf4db8 339 SUPERFAMILY SSF55846 44 181 3.6E-24 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CDW54_RS03730 ce9374a68172e7c793f5b314b1cf4db8 339 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 47 174 3.4E-13 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CDW54_RS00410 6cee5ad90a181f3ce4086eeb8e96d145 223 SUPERFAMILY SSF52317 1 218 2.72E-74 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CDW54_RS00410 6cee5ad90a181f3ce4086eeb8e96d145 223 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 201 2.7E-43 T 28-03-2018 CDW54_RS00410 6cee5ad90a181f3ce4086eeb8e96d145 223 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 1 216 5.0E-91 T 28-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CDW54_RS00410 6cee5ad90a181f3ce4086eeb8e96d145 223 Gene3D G3DSA:3.40.50.880 1 220 5.4E-39 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CDW54_RS00410 6cee5ad90a181f3ce4086eeb8e96d145 223 PIRSF PIRSF001586 1 221 8.5E-86 T 28-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CDW54_RS00410 6cee5ad90a181f3ce4086eeb8e96d145 223 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 1 216 44.065 T 28-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CDW54_RS00410 6cee5ad90a181f3ce4086eeb8e96d145 223 SMART SM01211 1 218 2.2E-134 T 28-03-2018 CDW54_RS09495 df6fc051b38e9dea9d50f779da79b91e 123 Gene3D G3DSA:3.10.180.10 1 123 7.4E-30 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDW54_RS09495 df6fc051b38e9dea9d50f779da79b91e 123 ProSitePatterns PS00934 Glyoxalase I signature 1. 5 26 - T 28-03-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 CDW54_RS09495 df6fc051b38e9dea9d50f779da79b91e 123 SUPERFAMILY SSF54593 1 121 1.06E-31 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDW54_RS09495 df6fc051b38e9dea9d50f779da79b91e 123 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3 120 1.8E-18 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CDW54_RS09970 fceeb37dd89825ed9304f962683056a0 142 Gene3D G3DSA:1.10.10.10 10 98 3.4E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS09970 fceeb37dd89825ed9304f962683056a0 142 SUPERFAMILY SSF46785 9 140 2.5E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS09970 fceeb37dd89825ed9304f962683056a0 142 Pfam PF01475 Ferric uptake regulator family 17 133 4.9E-25 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CDW54_RS09445 e688f4a78ee2de7427dd2524d587f9b1 194 SUPERFAMILY SSF160527 81 193 3.92E-9 T 28-03-2018 CDW54_RS04885 a01ea02ef0b5e9243c4f19d97e68ee81 689 SMART SM00740 432 502 2.9E-20 T 28-03-2018 IPR005543 PASTA domain CDW54_RS04885 a01ea02ef0b5e9243c4f19d97e68ee81 689 SMART SM00740 364 431 6.5E-15 T 28-03-2018 IPR005543 PASTA domain CDW54_RS04885 a01ea02ef0b5e9243c4f19d97e68ee81 689 SMART SM00740 503 572 2.4E-6 T 28-03-2018 IPR005543 PASTA domain CDW54_RS04885 a01ea02ef0b5e9243c4f19d97e68ee81 689 SMART SM00740 573 640 7.7E-7 T 28-03-2018 IPR005543 PASTA domain CDW54_RS04885 a01ea02ef0b5e9243c4f19d97e68ee81 689 Pfam PF00069 Protein kinase domain 12 258 1.2E-55 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CDW54_RS04885 a01ea02ef0b5e9243c4f19d97e68ee81 689 SUPERFAMILY SSF56112 8 270 1.35E-82 T 28-03-2018 IPR011009 Protein kinase-like domain CDW54_RS04885 a01ea02ef0b5e9243c4f19d97e68ee81 689 Pfam PF03793 PASTA domain 437 502 1.1E-16 T 28-03-2018 IPR005543 PASTA domain CDW54_RS04885 a01ea02ef0b5e9243c4f19d97e68ee81 689 Pfam PF03793 PASTA domain 367 430 4.1E-14 T 28-03-2018 IPR005543 PASTA domain CDW54_RS04885 a01ea02ef0b5e9243c4f19d97e68ee81 689 Pfam PF03793 PASTA domain 579 640 5.0E-10 T 28-03-2018 IPR005543 PASTA domain CDW54_RS04885 a01ea02ef0b5e9243c4f19d97e68ee81 689 Pfam PF03793 PASTA domain 513 572 4.6E-9 T 28-03-2018 IPR005543 PASTA domain CDW54_RS04885 a01ea02ef0b5e9243c4f19d97e68ee81 689 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 131 143 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CDW54_RS04885 a01ea02ef0b5e9243c4f19d97e68ee81 689 Gene3D G3DSA:1.10.510.10 81 688 6.4E-57 T 28-03-2018 CDW54_RS04885 a01ea02ef0b5e9243c4f19d97e68ee81 689 Gene3D G3DSA:3.30.200.20 1 80 2.6E-21 T 28-03-2018 CDW54_RS04885 a01ea02ef0b5e9243c4f19d97e68ee81 689 SMART SM00220 12 269 2.8E-70 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CDW54_RS04885 a01ea02ef0b5e9243c4f19d97e68ee81 689 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 18 41 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CDW54_RS12465 3826382fa55017d8eeae594920b070c7 449 Pfam PF00270 DEAD/DEAH box helicase 26 191 1.1E-41 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CDW54_RS12465 3826382fa55017d8eeae594920b070c7 449 Gene3D G3DSA:3.40.50.300 12 216 3.5E-49 T 28-03-2018 CDW54_RS12465 3826382fa55017d8eeae594920b070c7 449 SUPERFAMILY SSF52540 70 358 7.12E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS12465 3826382fa55017d8eeae594920b070c7 449 Pfam PF00271 Helicase conserved C-terminal domain 232 338 3.1E-26 T 28-03-2018 IPR001650 Helicase, C-terminal CDW54_RS12465 3826382fa55017d8eeae594920b070c7 449 SMART SM00490 257 338 3.5E-29 T 28-03-2018 IPR001650 Helicase, C-terminal CDW54_RS12465 3826382fa55017d8eeae594920b070c7 449 Gene3D G3DSA:3.40.50.300 217 449 6.4E-44 T 28-03-2018 CDW54_RS12465 3826382fa55017d8eeae594920b070c7 449 Hamap MF_01494 DEAD-box ATP-dependent RNA helicase CshB [cshB]. 2 436 52.791 T 28-03-2018 IPR030881 DEAD-box ATP-dependent RNA helicase CshB GO:0004386|GO:0009409 CDW54_RS12465 3826382fa55017d8eeae594920b070c7 449 SMART SM00487 21 221 1.5E-50 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CDW54_RS01205 f2aa5eb6204d17f6e891ae43a2989d1b 153 Gene3D G3DSA:3.40.930.10 2 152 4.8E-27 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CDW54_RS01205 f2aa5eb6204d17f6e891ae43a2989d1b 153 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 5 144 1.1E-28 T 28-03-2018 IPR002178 PTS EIIA type-2 domain CDW54_RS01205 f2aa5eb6204d17f6e891ae43a2989d1b 153 SUPERFAMILY SSF55804 5 149 1.31E-31 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CDW54_RS11070 c6f4d9f8678fbfd03c05d4d5ac896ba2 295 Gene3D G3DSA:3.40.1700.10 126 253 8.0E-35 T 28-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CDW54_RS11070 c6f4d9f8678fbfd03c05d4d5ac896ba2 295 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 133 250 4.6E-43 T 28-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CDW54_RS11070 c6f4d9f8678fbfd03c05d4d5ac896ba2 295 SUPERFAMILY SSF143597 56 252 9.94E-71 T 28-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CDW54_RS11070 c6f4d9f8678fbfd03c05d4d5ac896ba2 295 PIRSF PIRSF004793 18 284 2.9E-90 T 28-03-2018 IPR014046 Diadenylate cyclase GO:0004016|GO:0006171 CDW54_RS11070 c6f4d9f8678fbfd03c05d4d5ac896ba2 295 Hamap MF_01499 Diadenylate cyclase [dacA]. 21 269 33.01 T 28-03-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 CDW54_RS11070 c6f4d9f8678fbfd03c05d4d5ac896ba2 295 TIGRFAM TIGR00159 TIGR00159: TIGR00159 family protein 21 269 5.5E-88 T 28-03-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 CDW54_RS02405 a398d72d5397c486e1d1b77f28450240 257 Pfam PF08220 DeoR-like helix-turn-helix domain 8 62 8.6E-17 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CDW54_RS02405 a398d72d5397c486e1d1b77f28450240 257 SUPERFAMILY SSF46785 5 81 8.49E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS02405 a398d72d5397c486e1d1b77f28450240 257 SMART SM01134 77 238 7.8E-42 T 28-03-2018 CDW54_RS02405 a398d72d5397c486e1d1b77f28450240 257 Gene3D G3DSA:3.40.50.1360 72 241 5.8E-29 T 28-03-2018 CDW54_RS02405 a398d72d5397c486e1d1b77f28450240 257 Pfam PF00455 DeoR C terminal sensor domain 79 236 4.3E-39 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain CDW54_RS02405 a398d72d5397c486e1d1b77f28450240 257 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 26 40 9.3E-6 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CDW54_RS02405 a398d72d5397c486e1d1b77f28450240 257 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 40 58 9.3E-6 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CDW54_RS02405 a398d72d5397c486e1d1b77f28450240 257 SUPERFAMILY SSF100950 80 237 8.16E-27 T 28-03-2018 CDW54_RS02405 a398d72d5397c486e1d1b77f28450240 257 SMART SM00420 8 60 2.6E-17 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CDW54_RS02405 a398d72d5397c486e1d1b77f28450240 257 Gene3D G3DSA:1.10.10.10 1 60 4.5E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS04220 de9b34047ee01f90ffffb5dcb160356a 336 SUPERFAMILY SSF54534 142 237 1.18E-13 T 28-03-2018 CDW54_RS04220 de9b34047ee01f90ffffb5dcb160356a 336 SUPERFAMILY SSF109998 27 170 5.1E-20 T 28-03-2018 IPR027304 Trigger factor/SurA domain CDW54_RS04220 de9b34047ee01f90ffffb5dcb160356a 336 Gene3D G3DSA:3.10.50.40 135 263 1.8E-17 T 28-03-2018 CDW54_RS04220 de9b34047ee01f90ffffb5dcb160356a 336 Pfam PF00639 PPIC-type PPIASE domain 153 222 5.9E-11 T 28-03-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 CDW54_RS04220 de9b34047ee01f90ffffb5dcb160356a 336 Hamap MF_01145 Foldase protein PrsA [prsA]. 4 296 21.021 T 28-03-2018 IPR023059 Foldase protein PrsA GO:0003755 CDW54_RS04220 de9b34047ee01f90ffffb5dcb160356a 336 Gene3D G3DSA:1.10.4030.10 23 127 4.4E-10 T 28-03-2018 CDW54_RS06390 e28d4ffa2094c3d5905999116da6172b 148 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 5 132 37.766 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CDW54_RS06390 e28d4ffa2094c3d5905999116da6172b 148 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 8 140 9.1E-63 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CDW54_RS06390 e28d4ffa2094c3d5905999116da6172b 148 Pfam PF01641 SelR domain 11 131 3.3E-50 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CDW54_RS06390 e28d4ffa2094c3d5905999116da6172b 148 SUPERFAMILY SSF51316 6 145 6.28E-60 T 28-03-2018 IPR011057 Mss4-like CDW54_RS06390 e28d4ffa2094c3d5905999116da6172b 148 Gene3D G3DSA:2.170.150.20 1 148 4.8E-57 T 28-03-2018 CDW54_RS00925 52fb5c35b001c8e3fc62c0c692e220ec 226 TIGRFAM TIGR00017 cmk: cytidylate kinase 3 214 1.4E-81 T 28-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CDW54_RS00925 52fb5c35b001c8e3fc62c0c692e220ec 226 SUPERFAMILY SSF52540 1 217 1.86E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS00925 52fb5c35b001c8e3fc62c0c692e220ec 226 Gene3D G3DSA:3.40.50.300 1 221 1.1E-49 T 28-03-2018 CDW54_RS00925 52fb5c35b001c8e3fc62c0c692e220ec 226 Pfam PF02224 Cytidylate kinase 6 215 4.7E-76 T 28-03-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CDW54_RS00925 52fb5c35b001c8e3fc62c0c692e220ec 226 Hamap MF_00238 Cytidylate kinase [cmk]. 4 222 33.177 T 28-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CDW54_RS04610 4139320abe373bb3674a57fe79b8fb0c 397 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 245 383 2.5E-69 T 28-03-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CDW54_RS04610 4139320abe373bb3674a57fe79b8fb0c 397 Pfam PF02772 S-adenosylmethionine synthetase, central domain 125 243 4.2E-49 T 28-03-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CDW54_RS04610 4139320abe373bb3674a57fe79b8fb0c 397 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 3 395 58.471 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CDW54_RS04610 4139320abe373bb3674a57fe79b8fb0c 397 SUPERFAMILY SSF55973 124 244 6.08E-52 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CDW54_RS04610 4139320abe373bb3674a57fe79b8fb0c 397 Gene3D G3DSA:3.30.300.10 144 245 1.0E-48 T 28-03-2018 CDW54_RS04610 4139320abe373bb3674a57fe79b8fb0c 397 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 6 393 4.9E-186 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CDW54_RS04610 4139320abe373bb3674a57fe79b8fb0c 397 SUPERFAMILY SSF55973 245 393 3.92E-69 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CDW54_RS04610 4139320abe373bb3674a57fe79b8fb0c 397 PIRSF PIRSF000497 1 396 4.1E-179 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CDW54_RS04610 4139320abe373bb3674a57fe79b8fb0c 397 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 127 137 - T 28-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CDW54_RS04610 4139320abe373bb3674a57fe79b8fb0c 397 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 5 102 5.1E-44 T 28-03-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CDW54_RS04610 4139320abe373bb3674a57fe79b8fb0c 397 Gene3D G3DSA:3.30.300.10 12 143 6.6E-45 T 28-03-2018 CDW54_RS04610 4139320abe373bb3674a57fe79b8fb0c 397 SUPERFAMILY SSF55973 4 110 2.2E-48 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CDW54_RS04610 4139320abe373bb3674a57fe79b8fb0c 397 Gene3D G3DSA:3.30.300.10 258 397 6.6E-49 T 28-03-2018 CDW54_RS04610 4139320abe373bb3674a57fe79b8fb0c 397 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 271 279 - T 28-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CDW54_RS11025 64281396205a0138cca86dae8445d664 243 Gene3D G3DSA:3.40.50.1860 121 217 4.8E-19 T 28-03-2018 CDW54_RS11025 64281396205a0138cca86dae8445d664 243 TIGRFAM TIGR00035 asp_race: aspartate racemase 1 238 3.1E-112 T 28-03-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 CDW54_RS11025 64281396205a0138cca86dae8445d664 243 Gene3D G3DSA:3.40.50.1860 1 120 3.8E-31 T 28-03-2018 CDW54_RS11025 64281396205a0138cca86dae8445d664 243 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 81 89 - T 28-03-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDW54_RS11025 64281396205a0138cca86dae8445d664 243 Pfam PF01177 Asp/Glu/Hydantoin racemase 8 225 1.8E-66 T 28-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDW54_RS11025 64281396205a0138cca86dae8445d664 243 SUPERFAMILY SSF53681 5 115 8.24E-29 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDW54_RS11025 64281396205a0138cca86dae8445d664 243 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 193 203 - T 28-03-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDW54_RS11025 64281396205a0138cca86dae8445d664 243 SUPERFAMILY SSF53681 120 230 7.19E-24 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDW54_RS11655 2bd7f2bac6e502eb4cdfccb52a56b339 132 Gene3D G3DSA:2.40.33.40 2 117 1.9E-37 T 28-03-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 CDW54_RS11655 2bd7f2bac6e502eb4cdfccb52a56b339 132 SUPERFAMILY SSF141530 3 117 2.48E-37 T 28-03-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 CDW54_RS11655 2bd7f2bac6e502eb4cdfccb52a56b339 132 ProDom PD015842 PTS IIA COMPONENT GLUCITOL/SORBITOL-SPECIFIC SYSTEM ENZYME TRANSFERASE SYSTEM PHOSPHOTRANSFERASE EIIA 8 116 2.0E-58 T 28-03-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 CDW54_RS11655 2bd7f2bac6e502eb4cdfccb52a56b339 132 Pfam PF03829 PTS system glucitol/sorbitol-specific IIA component 3 115 2.0E-38 T 28-03-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 CDW54_RS02395 ab03aee21a8aadf4ec890f340a9f746a 402 ProSitePatterns PS00216 Sugar transport proteins signature 1. 64 81 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CDW54_RS02395 ab03aee21a8aadf4ec890f340a9f746a 402 SUPERFAMILY SSF103473 4 387 2.09E-57 T 28-03-2018 IPR020846 Major facilitator superfamily domain CDW54_RS02395 ab03aee21a8aadf4ec890f340a9f746a 402 Pfam PF07690 Major Facilitator Superfamily 14 295 1.3E-32 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDW54_RS02395 ab03aee21a8aadf4ec890f340a9f746a 402 Gene3D G3DSA:1.20.1250.20 3 199 3.3E-30 T 28-03-2018 CDW54_RS02395 ab03aee21a8aadf4ec890f340a9f746a 402 Gene3D G3DSA:1.20.1250.20 203 397 3.8E-23 T 28-03-2018 CDW54_RS09615 304d7809d3d5293ab1d66f644f42a66f 248 Pfam PF12146 Serine aminopeptidase, S33 14 142 3.3E-12 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CDW54_RS09615 304d7809d3d5293ab1d66f644f42a66f 248 Gene3D G3DSA:3.40.50.1820 2 245 6.5E-32 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CDW54_RS09615 304d7809d3d5293ab1d66f644f42a66f 248 SUPERFAMILY SSF53474 11 244 1.68E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CDW54_RS09615 304d7809d3d5293ab1d66f644f42a66f 248 PIRSF PIRSF017388 2 245 8.5E-68 T 28-03-2018 IPR012354 Esterase/lipase GO:0052689 CDW54_RS00980 5553e8ce03a387bddbdf34e6303ed965 265 Pfam PF02616 Segregation and condensation protein ScpA 33 250 6.8E-44 T 28-03-2018 IPR003768 Segregation and condensation protein A CDW54_RS00980 5553e8ce03a387bddbdf34e6303ed965 265 Hamap MF_01805 Segregation and condensation protein A [scpA]. 16 256 24.805 T 28-03-2018 IPR003768 Segregation and condensation protein A CDW54_RS00980 5553e8ce03a387bddbdf34e6303ed965 265 Gene3D G3DSA:1.10.10.580 188 255 4.3E-13 T 28-03-2018 CDW54_RS07770 f860a70a1be4d669a5f4976408155bea 542 Pfam PF00128 Alpha amylase, catalytic domain 25 364 2.4E-105 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CDW54_RS07770 f860a70a1be4d669a5f4976408155bea 542 SUPERFAMILY SSF51011 467 540 6.09E-15 T 28-03-2018 CDW54_RS07770 f860a70a1be4d669a5f4976408155bea 542 Gene3D G3DSA:2.60.40.1180 468 542 1.6E-17 T 28-03-2018 CDW54_RS07770 f860a70a1be4d669a5f4976408155bea 542 SMART SM00642 10 406 4.8E-130 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CDW54_RS07770 f860a70a1be4d669a5f4976408155bea 542 SUPERFAMILY SSF51445 3 463 1.22E-142 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CDW54_RS07770 f860a70a1be4d669a5f4976408155bea 542 TIGRFAM TIGR02403 trehalose_treC: alpha,alpha-phosphotrehalase 3 539 1.5E-256 T 28-03-2018 IPR012769 Trehalose-6-phosphate hydrolase GO:0005737|GO:0005993|GO:0008788 KEGG: 00500+3.2.1.93 CDW54_RS07770 f860a70a1be4d669a5f4976408155bea 542 Gene3D G3DSA:3.20.20.80 2 467 2.8E-116 T 28-03-2018 CDW54_RS07945 7a35ec62386271a024921704e9cc1048 459 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 336 438 2.6E-6 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CDW54_RS07945 7a35ec62386271a024921704e9cc1048 459 Gene3D G3DSA:3.50.50.60 249 328 8.4E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS07945 7a35ec62386271a024921704e9cc1048 459 SUPERFAMILY SSF55424 328 453 5.84E-26 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CDW54_RS07945 7a35ec62386271a024921704e9cc1048 459 Gene3D G3DSA:3.30.390.30 331 455 3.0E-15 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CDW54_RS07945 7a35ec62386271a024921704e9cc1048 459 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 310 2.2E-64 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS07945 7a35ec62386271a024921704e9cc1048 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 2.0E-23 T 28-03-2018 CDW54_RS07945 7a35ec62386271a024921704e9cc1048 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 265 287 2.0E-23 T 28-03-2018 CDW54_RS07945 7a35ec62386271a024921704e9cc1048 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 108 126 2.0E-23 T 28-03-2018 CDW54_RS07945 7a35ec62386271a024921704e9cc1048 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 239 255 2.0E-23 T 28-03-2018 CDW54_RS07945 7a35ec62386271a024921704e9cc1048 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 2.0E-23 T 28-03-2018 CDW54_RS07945 7a35ec62386271a024921704e9cc1048 459 Gene3D G3DSA:3.50.50.60 108 248 4.3E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS07945 7a35ec62386271a024921704e9cc1048 459 SUPERFAMILY SSF51905 1 319 2.51E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS07945 7a35ec62386271a024921704e9cc1048 459 Gene3D G3DSA:3.50.50.60 2 107 1.5E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS07945 7a35ec62386271a024921704e9cc1048 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 8.7E-14 T 28-03-2018 CDW54_RS07945 7a35ec62386271a024921704e9cc1048 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 240 254 8.7E-14 T 28-03-2018 CDW54_RS07945 7a35ec62386271a024921704e9cc1048 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 280 287 8.7E-14 T 28-03-2018 CDW54_RS07945 7a35ec62386271a024921704e9cc1048 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 155 180 8.7E-14 T 28-03-2018 CDW54_RS04025 6186113af6758bff410b42f50f362b3c 244 Gene3D G3DSA:3.40.50.150 26 209 6.4E-35 T 28-03-2018 CDW54_RS04025 6186113af6758bff410b42f50f362b3c 244 SUPERFAMILY SSF53335 14 199 2.69E-30 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDW54_RS04025 6186113af6758bff410b42f50f362b3c 244 Pfam PF05175 Methyltransferase small domain 18 139 6.2E-14 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CDW54_RS04025 6186113af6758bff410b42f50f362b3c 244 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 116 122 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CDW54_RS03980 49775be071a865db42e3b8ba74ae9f96 602 Gene3D G3DSA:1.10.1370.10 79 596 4.3E-41 T 28-03-2018 CDW54_RS03980 49775be071a865db42e3b8ba74ae9f96 602 SUPERFAMILY SSF55486 57 601 3.09E-137 T 28-03-2018 CDW54_RS03980 49775be071a865db42e3b8ba74ae9f96 602 Pfam PF01432 Peptidase family M3 206 586 2.7E-80 T 28-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 CDW54_RS03980 49775be071a865db42e3b8ba74ae9f96 602 TIGRFAM TIGR00181 pepF: oligoendopeptidase F 9 597 5.2E-192 T 28-03-2018 IPR004438 Peptidase M3B, oligoendopeptidase F GO:0004222|GO:0006508 CDW54_RS03980 49775be071a865db42e3b8ba74ae9f96 602 Pfam PF08439 Oligopeptidase F 116 185 3.0E-22 T 28-03-2018 IPR013647 Oligopeptidase F, N-terminal domain CDW54_RS06715 d386faf44d528f2afbe358749283fe03 429 SUPERFAMILY SSF51182 216 413 8.01E-81 T 28-03-2018 IPR011051 RmlC-like cupin domain CDW54_RS06715 d386faf44d528f2afbe358749283fe03 429 Gene3D G3DSA:2.60.120.10 282 429 6.0E-48 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CDW54_RS06715 d386faf44d528f2afbe358749283fe03 429 Pfam PF04962 KduI/IolB family 231 420 2.8E-28 T 28-03-2018 IPR021120 KduI/IolB isomerase GO:0016861 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 CDW54_RS06715 d386faf44d528f2afbe358749283fe03 429 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 10 234 7.2E-55 T 28-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CDW54_RS06715 d386faf44d528f2afbe358749283fe03 429 Gene3D G3DSA:2.60.120.520 221 281 1.5E-22 T 28-03-2018 IPR027449 5-keto-4-deoxyuronate isomerase, N-terminal domain KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 CDW54_RS12135 5bfbd24872f7d00f1f07aa1b8278b8a1 547 Gene3D G3DSA:2.60.40.1180 471 547 7.0E-17 T 28-03-2018 CDW54_RS12135 5bfbd24872f7d00f1f07aa1b8278b8a1 547 PRINTS PR00110 Alpha-amylase signature 195 206 4.9E-5 T 28-03-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 CDW54_RS12135 5bfbd24872f7d00f1f07aa1b8278b8a1 547 PRINTS PR00110 Alpha-amylase signature 94 105 4.9E-5 T 28-03-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 CDW54_RS12135 5bfbd24872f7d00f1f07aa1b8278b8a1 547 PRINTS PR00110 Alpha-amylase signature 309 321 4.9E-5 T 28-03-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 CDW54_RS12135 5bfbd24872f7d00f1f07aa1b8278b8a1 547 Gene3D G3DSA:3.90.400.10 105 169 3.7E-30 T 28-03-2018 CDW54_RS12135 5bfbd24872f7d00f1f07aa1b8278b8a1 547 Gene3D G3DSA:3.20.20.470 2 97 3.9E-35 T 28-03-2018 CDW54_RS12135 5bfbd24872f7d00f1f07aa1b8278b8a1 547 Gene3D G3DSA:3.20.20.80 334 468 1.3E-20 T 28-03-2018 CDW54_RS12135 5bfbd24872f7d00f1f07aa1b8278b8a1 547 SUPERFAMILY SSF51011 470 544 1.26E-13 T 28-03-2018 CDW54_RS12135 5bfbd24872f7d00f1f07aa1b8278b8a1 547 SMART SM00642 15 409 4.1E-137 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CDW54_RS12135 5bfbd24872f7d00f1f07aa1b8278b8a1 547 Gene3D G3DSA:3.20.20.470 170 333 1.3E-31 T 28-03-2018 CDW54_RS12135 5bfbd24872f7d00f1f07aa1b8278b8a1 547 Pfam PF00128 Alpha amylase, catalytic domain 30 366 3.9E-106 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CDW54_RS12135 5bfbd24872f7d00f1f07aa1b8278b8a1 547 SUPERFAMILY SSF51445 5 467 1.82E-144 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CDW54_RS06195 11bb54e50240b5cfe07b4994b9380246 228 Gene3D G3DSA:3.30.160.20 149 225 1.6E-21 T 28-03-2018 CDW54_RS06195 11bb54e50240b5cfe07b4994b9380246 228 SUPERFAMILY SSF69065 6 154 2.62E-50 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CDW54_RS06195 11bb54e50240b5cfe07b4994b9380246 228 Hamap MF_00104 Ribonuclease 3 [rnc]. 9 225 31.121 T 28-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 CDW54_RS06195 11bb54e50240b5cfe07b4994b9380246 228 SMART SM00535 21 156 1.2E-58 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CDW54_RS06195 11bb54e50240b5cfe07b4994b9380246 228 ProSitePatterns PS00517 Ribonuclease III family signature. 45 53 - T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CDW54_RS06195 11bb54e50240b5cfe07b4994b9380246 228 Pfam PF14622 Ribonuclease-III-like 21 150 4.6E-38 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CDW54_RS06195 11bb54e50240b5cfe07b4994b9380246 228 SMART SM00358 162 228 3.2E-19 T 28-03-2018 IPR014720 Double-stranded RNA-binding domain CDW54_RS06195 11bb54e50240b5cfe07b4994b9380246 228 Pfam PF00035 Double-stranded RNA binding motif 163 228 1.9E-17 T 28-03-2018 IPR014720 Double-stranded RNA-binding domain CDW54_RS06195 11bb54e50240b5cfe07b4994b9380246 228 Gene3D G3DSA:1.10.1520.10 5 148 2.2E-45 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CDW54_RS06195 11bb54e50240b5cfe07b4994b9380246 228 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 10 227 5.0E-82 T 28-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 CDW54_RS06195 11bb54e50240b5cfe07b4994b9380246 228 SUPERFAMILY SSF54768 157 228 2.04E-23 T 28-03-2018 CDW54_RS01925 ef818ffc05e8fb4b36fcba14b8bfde17 410 Gene3D G3DSA:3.40.1830.10 6 176 2.6E-54 T 28-03-2018 IPR035097 Peptidase M29, N-terminal CDW54_RS01925 ef818ffc05e8fb4b36fcba14b8bfde17 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 246 265 2.9E-63 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CDW54_RS01925 ef818ffc05e8fb4b36fcba14b8bfde17 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 157 179 2.9E-63 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CDW54_RS01925 ef818ffc05e8fb4b36fcba14b8bfde17 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 325 346 2.9E-63 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CDW54_RS01925 ef818ffc05e8fb4b36fcba14b8bfde17 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 302 322 2.9E-63 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CDW54_RS01925 ef818ffc05e8fb4b36fcba14b8bfde17 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 364 386 2.9E-63 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CDW54_RS01925 ef818ffc05e8fb4b36fcba14b8bfde17 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 390 409 2.9E-63 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CDW54_RS01925 ef818ffc05e8fb4b36fcba14b8bfde17 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 16 33 2.9E-63 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CDW54_RS01925 ef818ffc05e8fb4b36fcba14b8bfde17 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 81 100 2.9E-63 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CDW54_RS01925 ef818ffc05e8fb4b36fcba14b8bfde17 410 SUPERFAMILY SSF144052 5 410 2.88E-144 T 28-03-2018 CDW54_RS01925 ef818ffc05e8fb4b36fcba14b8bfde17 410 Pfam PF02073 Thermophilic metalloprotease (M29) 6 409 5.1E-170 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CDW54_RS08265 abe63cca93c9bb6969af5cd49bb71d07 690 Pfam PF01751 Toprim domain 3 132 1.2E-14 T 28-03-2018 IPR006171 TOPRIM domain CDW54_RS08265 abe63cca93c9bb6969af5cd49bb71d07 690 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 185 203 1.9E-24 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CDW54_RS08265 abe63cca93c9bb6969af5cd49bb71d07 690 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 302 311 1.9E-24 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CDW54_RS08265 abe63cca93c9bb6969af5cd49bb71d07 690 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 476 490 1.9E-24 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CDW54_RS08265 abe63cca93c9bb6969af5cd49bb71d07 690 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 99 112 1.9E-24 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CDW54_RS08265 abe63cca93c9bb6969af5cd49bb71d07 690 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 383 399 1.9E-24 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CDW54_RS08265 abe63cca93c9bb6969af5cd49bb71d07 690 SMART SM00493 2 125 2.2E-17 T 28-03-2018 IPR006171 TOPRIM domain CDW54_RS08265 abe63cca93c9bb6969af5cd49bb71d07 690 Gene3D G3DSA:3.40.50.140 2 153 1.1E-41 T 28-03-2018 CDW54_RS08265 abe63cca93c9bb6969af5cd49bb71d07 690 SMART SM00436 125 215 7.9E-36 T 28-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 CDW54_RS08265 abe63cca93c9bb6969af5cd49bb71d07 690 Gene3D G3DSA:2.70.20.10 340 455 1.2E-16 T 28-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CDW54_RS08265 abe63cca93c9bb6969af5cd49bb71d07 690 Gene3D G3DSA:1.10.460.10 456 564 1.6E-16 T 28-03-2018 CDW54_RS08265 abe63cca93c9bb6969af5cd49bb71d07 690 Gene3D G3DSA:1.10.460.10 158 339 7.4E-41 T 28-03-2018 CDW54_RS08265 abe63cca93c9bb6969af5cd49bb71d07 690 TIGRFAM TIGR01056 topB: DNA topoisomerase III 1 674 3.5E-171 T 28-03-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 CDW54_RS08265 abe63cca93c9bb6969af5cd49bb71d07 690 Pfam PF01131 DNA topoisomerase 151 547 1.1E-110 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CDW54_RS08265 abe63cca93c9bb6969af5cd49bb71d07 690 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 296 311 - T 28-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 CDW54_RS08265 abe63cca93c9bb6969af5cd49bb71d07 690 SUPERFAMILY SSF56712 2 562 7.19E-158 T 28-03-2018 IPR023405 DNA topoisomerase, type IA, core domain CDW54_RS08265 abe63cca93c9bb6969af5cd49bb71d07 690 SMART SM00437 259 513 1.5E-48 T 28-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 CDW54_RS08265 abe63cca93c9bb6969af5cd49bb71d07 690 Gene3D G3DSA:3.30.65.10 565 610 8.0E-8 T 28-03-2018 CDW54_RS08265 abe63cca93c9bb6969af5cd49bb71d07 690 Gene3D G3DSA:3.30.65.10 611 660 3.4E-4 T 28-03-2018 CDW54_RS02965 6262dfcb2f356c29e15f09a33142218e 285 Gene3D G3DSA:1.10.10.60 214 262 7.3E-8 T 28-03-2018 CDW54_RS02965 6262dfcb2f356c29e15f09a33142218e 285 Pfam PF13556 PucR C-terminal helix-turn-helix domain 236 280 3.4E-12 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CDW54_RS02965 6262dfcb2f356c29e15f09a33142218e 285 SUPERFAMILY SSF46689 197 259 6.72E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDW54_RS05110 227530b8408908cba549569e997d8147 175 SUPERFAMILY SSF51283 69 173 4.8E-32 T 28-03-2018 IPR029054 dUTPase-like CDW54_RS05110 227530b8408908cba549569e997d8147 175 SUPERFAMILY SSF51283 4 41 4.8E-32 T 28-03-2018 IPR029054 dUTPase-like CDW54_RS05110 227530b8408908cba549569e997d8147 175 Gene3D G3DSA:2.70.40.10 5 127 6.4E-27 T 28-03-2018 CDW54_RS05110 227530b8408908cba549569e997d8147 175 Gene3D G3DSA:2.70.40.10 128 174 7.8E-8 T 28-03-2018 CDW54_RS05110 227530b8408908cba549569e997d8147 175 Pfam PF00692 dUTPase 72 173 3.8E-11 T 28-03-2018 IPR029054 dUTPase-like CDW54_RS09555 fe905a6ecc165da3fbe3fd683e5c6bc8 444 PIRSF PIRSF000774 3 443 5.2E-123 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CDW54_RS09555 fe905a6ecc165da3fbe3fd683e5c6bc8 444 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 8 53 1.0E-14 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CDW54_RS09555 fe905a6ecc165da3fbe3fd683e5c6bc8 444 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 327 346 - T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CDW54_RS09555 fe905a6ecc165da3fbe3fd683e5c6bc8 444 Pfam PF04963 Sigma-54 factor, core binding domain 80 266 2.8E-43 T 28-03-2018 IPR007046 RNA polymerase sigma factor 54, core-binding GO:0003677|GO:0006352 CDW54_RS09555 fe905a6ecc165da3fbe3fd683e5c6bc8 444 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 13 440 4.7E-135 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CDW54_RS09555 fe905a6ecc165da3fbe3fd683e5c6bc8 444 PRINTS PR00045 Sigma-54 factor signature 416 434 4.8E-23 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CDW54_RS09555 fe905a6ecc165da3fbe3fd683e5c6bc8 444 PRINTS PR00045 Sigma-54 factor signature 355 366 4.8E-23 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CDW54_RS09555 fe905a6ecc165da3fbe3fd683e5c6bc8 444 PRINTS PR00045 Sigma-54 factor signature 339 351 4.8E-23 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CDW54_RS09555 fe905a6ecc165da3fbe3fd683e5c6bc8 444 PRINTS PR00045 Sigma-54 factor signature 151 168 4.8E-23 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CDW54_RS09555 fe905a6ecc165da3fbe3fd683e5c6bc8 444 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 421 428 - T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CDW54_RS09555 fe905a6ecc165da3fbe3fd683e5c6bc8 444 Pfam PF04552 Sigma-54, DNA binding domain 280 441 4.6E-61 T 28-03-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding CDW54_RS09555 fe905a6ecc165da3fbe3fd683e5c6bc8 444 Gene3D G3DSA:1.10.10.10 285 378 5.3E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS10915 14eacbc95144ab53ad357c4c2ee7e408 261 SUPERFAMILY SSF51735 6 253 8.49E-88 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS10915 14eacbc95144ab53ad357c4c2ee7e408 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CDW54_RS10915 14eacbc95144ab53ad357c4c2ee7e408 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 251 9.3E-71 T 28-03-2018 CDW54_RS10915 14eacbc95144ab53ad357c4c2ee7e408 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 1.6E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS10915 14eacbc95144ab53ad357c4c2ee7e408 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.6E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS10915 14eacbc95144ab53ad357c4c2ee7e408 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.6E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS10915 14eacbc95144ab53ad357c4c2ee7e408 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.6E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS10915 14eacbc95144ab53ad357c4c2ee7e408 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.6E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS10915 14eacbc95144ab53ad357c4c2ee7e408 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.6E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS10915 14eacbc95144ab53ad357c4c2ee7e408 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 1.6E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS10915 14eacbc95144ab53ad357c4c2ee7e408 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 1.6E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS10915 14eacbc95144ab53ad357c4c2ee7e408 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.6E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS10915 14eacbc95144ab53ad357c4c2ee7e408 261 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 194 0.0065 T 28-03-2018 CDW54_RS10915 14eacbc95144ab53ad357c4c2ee7e408 261 Gene3D G3DSA:3.40.50.720 43 258 8.0E-70 T 28-03-2018 CDW54_RS10915 14eacbc95144ab53ad357c4c2ee7e408 261 Gene3D G3DSA:3.40.50.720 1 42 3.7E-9 T 28-03-2018 CDW54_RS08015 89a43f3c29ba73b9ec5a9e11383ae495 316 SUPERFAMILY SSF53807 15 311 1.96E-87 T 28-03-2018 CDW54_RS08015 89a43f3c29ba73b9ec5a9e11383ae495 316 Gene3D G3DSA:3.40.50.1980 190 311 3.7E-37 T 28-03-2018 CDW54_RS08015 89a43f3c29ba73b9ec5a9e11383ae495 316 PRINTS PR00691 Adhesin B signature 61 79 7.9E-83 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CDW54_RS08015 89a43f3c29ba73b9ec5a9e11383ae495 316 PRINTS PR00691 Adhesin B signature 246 263 7.9E-83 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CDW54_RS08015 89a43f3c29ba73b9ec5a9e11383ae495 316 PRINTS PR00691 Adhesin B signature 268 286 7.9E-83 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CDW54_RS08015 89a43f3c29ba73b9ec5a9e11383ae495 316 PRINTS PR00691 Adhesin B signature 139 158 7.9E-83 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CDW54_RS08015 89a43f3c29ba73b9ec5a9e11383ae495 316 PRINTS PR00691 Adhesin B signature 80 99 7.9E-83 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CDW54_RS08015 89a43f3c29ba73b9ec5a9e11383ae495 316 PRINTS PR00691 Adhesin B signature 36 57 7.9E-83 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CDW54_RS08015 89a43f3c29ba73b9ec5a9e11383ae495 316 PRINTS PR00691 Adhesin B signature 197 214 7.9E-83 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CDW54_RS08015 89a43f3c29ba73b9ec5a9e11383ae495 316 PRINTS PR00691 Adhesin B signature 289 307 7.9E-83 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CDW54_RS08015 89a43f3c29ba73b9ec5a9e11383ae495 316 PRINTS PR00691 Adhesin B signature 223 241 7.9E-83 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CDW54_RS08015 89a43f3c29ba73b9ec5a9e11383ae495 316 Gene3D G3DSA:3.40.50.1980 25 189 1.1E-44 T 28-03-2018 CDW54_RS08015 89a43f3c29ba73b9ec5a9e11383ae495 316 PRINTS PR00690 Adhesin family signature 36 54 9.3E-53 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CDW54_RS08015 89a43f3c29ba73b9ec5a9e11383ae495 316 PRINTS PR00690 Adhesin family signature 276 295 9.3E-53 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CDW54_RS08015 89a43f3c29ba73b9ec5a9e11383ae495 316 PRINTS PR00690 Adhesin family signature 80 97 9.3E-53 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CDW54_RS08015 89a43f3c29ba73b9ec5a9e11383ae495 316 PRINTS PR00690 Adhesin family signature 197 218 9.3E-53 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CDW54_RS08015 89a43f3c29ba73b9ec5a9e11383ae495 316 PRINTS PR00690 Adhesin family signature 67 80 9.3E-53 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CDW54_RS08015 89a43f3c29ba73b9ec5a9e11383ae495 316 PRINTS PR00690 Adhesin family signature 250 268 9.3E-53 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CDW54_RS08015 89a43f3c29ba73b9ec5a9e11383ae495 316 Pfam PF01297 Zinc-uptake complex component A periplasmic 39 308 6.0E-75 T 28-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 CDW54_RS00535 d82ace8d8140b4317f5bb52cb8b056d1 549 Gene3D G3DSA:1.10.287.130 325 380 1.2E-18 T 28-03-2018 CDW54_RS00535 d82ace8d8140b4317f5bb52cb8b056d1 549 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 326 385 7.3E-18 T 28-03-2018 CDW54_RS00535 d82ace8d8140b4317f5bb52cb8b056d1 549 Gene3D G3DSA:3.30.565.10 398 548 7.2E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS00535 d82ace8d8140b4317f5bb52cb8b056d1 549 Pfam PF17203 Single cache domain 3 52 173 3.3E-17 T 28-03-2018 IPR033463 Single cache domain 3 CDW54_RS00535 d82ace8d8140b4317f5bb52cb8b056d1 549 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 429 536 3.7E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS00535 d82ace8d8140b4317f5bb52cb8b056d1 549 SMART SM00387 425 537 1.4E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS00535 d82ace8d8140b4317f5bb52cb8b056d1 549 SUPERFAMILY SSF55874 427 534 6.02E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS00535 d82ace8d8140b4317f5bb52cb8b056d1 549 Gene3D G3DSA:3.30.450.20 39 176 1.9E-21 T 28-03-2018 CDW54_RS00535 d82ace8d8140b4317f5bb52cb8b056d1 549 Gene3D G3DSA:3.30.450.20 197 324 2.1E-4 T 28-03-2018 CDW54_RS00535 d82ace8d8140b4317f5bb52cb8b056d1 549 SUPERFAMILY SSF55890 328 448 4.45E-20 T 28-03-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 CDW54_RS00535 d82ace8d8140b4317f5bb52cb8b056d1 549 SUPERFAMILY SSF103190 42 173 1.37E-32 T 28-03-2018 IPR029151 Periplasmic sensor domain-like CDW54_RS00535 d82ace8d8140b4317f5bb52cb8b056d1 549 PRINTS PR00344 Bacterial sensor protein C-terminal signature 468 482 1.7E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDW54_RS00535 d82ace8d8140b4317f5bb52cb8b056d1 549 PRINTS PR00344 Bacterial sensor protein C-terminal signature 497 515 1.7E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDW54_RS00535 d82ace8d8140b4317f5bb52cb8b056d1 549 PRINTS PR00344 Bacterial sensor protein C-terminal signature 521 534 1.7E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDW54_RS06160 80b9527ec71e645a6926abe0d1563e73 80 Gene3D G3DSA:1.10.1200.10 1 80 1.1E-21 T 28-03-2018 CDW54_RS06160 80b9527ec71e645a6926abe0d1563e73 80 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 4 78 5.9E-24 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CDW54_RS06160 80b9527ec71e645a6926abe0d1563e73 80 SUPERFAMILY SSF47336 2 79 7.46E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDW54_RS06160 80b9527ec71e645a6926abe0d1563e73 80 Hamap MF_01217 Acyl carrier protein [acpP]. 5 79 18.083 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CDW54_RS06160 80b9527ec71e645a6926abe0d1563e73 80 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 44 79 4.0E-13 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CDW54_RS06160 80b9527ec71e645a6926abe0d1563e73 80 Pfam PF00550 Phosphopantetheine attachment site 9 75 2.7E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDW54_RS07540 01fcd294be91d37f062ce5ec5231a816 339 SUPERFAMILY SSF53822 63 333 2.57E-53 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CDW54_RS07540 01fcd294be91d37f062ce5ec5231a816 339 Gene3D G3DSA:1.10.260.40 3 56 2.7E-21 T 28-03-2018 CDW54_RS07540 01fcd294be91d37f062ce5ec5231a816 339 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 2.9E-6 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS07540 01fcd294be91d37f062ce5ec5231a816 339 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 2.9E-6 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS07540 01fcd294be91d37f062ce5ec5231a816 339 SMART SM00354 2 72 4.9E-27 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS07540 01fcd294be91d37f062ce5ec5231a816 339 Gene3D G3DSA:3.40.50.2300 185 339 4.7E-24 T 28-03-2018 CDW54_RS07540 01fcd294be91d37f062ce5ec5231a816 339 Gene3D G3DSA:3.40.50.2300 57 184 2.5E-24 T 28-03-2018 CDW54_RS07540 01fcd294be91d37f062ce5ec5231a816 339 Pfam PF13377 Periplasmic binding protein-like domain 176 332 1.7E-27 T 28-03-2018 CDW54_RS07540 01fcd294be91d37f062ce5ec5231a816 339 SUPERFAMILY SSF47413 3 57 3.75E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDW54_RS07540 01fcd294be91d37f062ce5ec5231a816 339 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 2.8E-20 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS04305 f14c6ef84610812bde03fa656b8de3c6 445 SUPERFAMILY SSF51126 2 367 5.57E-102 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CDW54_RS04305 f14c6ef84610812bde03fa656b8de3c6 445 Pfam PF00295 Glycosyl hydrolases family 28 34 300 3.2E-51 T 28-03-2018 IPR000743 Glycoside hydrolase, family 28 GO:0004650|GO:0005975 CDW54_RS04305 f14c6ef84610812bde03fa656b8de3c6 445 ProSitePatterns PS00502 Polygalacturonase active site. 226 240 - T 28-03-2018 IPR000743 Glycoside hydrolase, family 28 GO:0004650|GO:0005975 CDW54_RS04305 f14c6ef84610812bde03fa656b8de3c6 445 SMART SM00710 246 267 9.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CDW54_RS04305 f14c6ef84610812bde03fa656b8de3c6 445 SMART SM00710 219 240 1.6 T 28-03-2018 IPR006626 Parallel beta-helix repeat CDW54_RS04305 f14c6ef84610812bde03fa656b8de3c6 445 SMART SM00710 160 186 85.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CDW54_RS04305 f14c6ef84610812bde03fa656b8de3c6 445 SMART SM00710 187 208 4.1 T 28-03-2018 IPR006626 Parallel beta-helix repeat CDW54_RS04305 f14c6ef84610812bde03fa656b8de3c6 445 Gene3D G3DSA:2.160.20.10 9 378 2.4E-107 T 28-03-2018 IPR012334 Pectin lyase fold CDW54_RS05890 cf48223270ca0a4991359037d5e2c9dd 227 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 4 218 1.1E-83 T 28-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CDW54_RS05890 cf48223270ca0a4991359037d5e2c9dd 227 Gene3D G3DSA:3.30.70.260 137 201 9.1E-23 T 28-03-2018 CDW54_RS05890 cf48223270ca0a4991359037d5e2c9dd 227 SUPERFAMILY SSF100950 2 141 2.55E-45 T 28-03-2018 CDW54_RS05890 cf48223270ca0a4991359037d5e2c9dd 227 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 1 221 32.584 T 28-03-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CDW54_RS05890 cf48223270ca0a4991359037d5e2c9dd 227 SUPERFAMILY SSF75445 126 204 5.23E-22 T 28-03-2018 CDW54_RS05890 cf48223270ca0a4991359037d5e2c9dd 227 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 49 217 1.1E-61 T 28-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CDW54_RS05890 cf48223270ca0a4991359037d5e2c9dd 227 Gene3D G3DSA:3.40.50.1360 1 136 8.4E-42 T 28-03-2018 CDW54_RS03925 1c53c7d686a57cbdab09fefdea769c35 862 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 9 743 8.2E-264 T 28-03-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 CDW54_RS03925 1c53c7d686a57cbdab09fefdea769c35 862 Gene3D G3DSA:1.10.150.20 106 149 1.3E-5 T 28-03-2018 CDW54_RS03925 1c53c7d686a57cbdab09fefdea769c35 862 Gene3D G3DSA:1.10.150.20 161 214 0.015 T 28-03-2018 CDW54_RS03925 1c53c7d686a57cbdab09fefdea769c35 862 Pfam PF13604 AAA domain 336 531 2.7E-48 T 28-03-2018 CDW54_RS03925 1c53c7d686a57cbdab09fefdea769c35 862 Pfam PF13538 UvrD-like helicase C-terminal domain 671 717 8.8E-17 T 28-03-2018 IPR027785 UvrD-like helicase C-terminal domain CDW54_RS03925 1c53c7d686a57cbdab09fefdea769c35 862 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 6 747 29.44 T 28-03-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 CDW54_RS03925 1c53c7d686a57cbdab09fefdea769c35 862 SUPERFAMILY SSF52540 190 506 2.24E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS03925 1c53c7d686a57cbdab09fefdea769c35 862 Gene3D G3DSA:3.40.50.300 293 519 2.8E-32 T 28-03-2018 CDW54_RS03925 1c53c7d686a57cbdab09fefdea769c35 862 Gene3D G3DSA:3.40.50.300 520 731 1.2E-28 T 28-03-2018 CDW54_RS03925 1c53c7d686a57cbdab09fefdea769c35 862 Gene3D G3DSA:1.10.150.20 49 105 0.22 T 28-03-2018 CDW54_RS03925 1c53c7d686a57cbdab09fefdea769c35 862 SMART SM00382 349 500 7.4E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS03925 1c53c7d686a57cbdab09fefdea769c35 862 SUPERFAMILY SSF52540 563 740 7.59E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS03925 1c53c7d686a57cbdab09fefdea769c35 862 SUPERFAMILY SSF52540 459 524 7.59E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS03925 1c53c7d686a57cbdab09fefdea769c35 862 Pfam PF14490 Helix-hairpin-helix containing domain 152 241 3.3E-30 T 28-03-2018 IPR029493 RecD helicase-like helix-hairpin-helix domain CDW54_RS04910 ecae2d3b45d76b50ad97986cb6b6c314 802 Gene3D G3DSA:3.40.50.300 559 686 2.5E-15 T 28-03-2018 CDW54_RS04910 ecae2d3b45d76b50ad97986cb6b6c314 802 SUPERFAMILY SSF52540 185 447 3.22E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS04910 ecae2d3b45d76b50ad97986cb6b6c314 802 Pfam PF00271 Helicase conserved C-terminal domain 576 660 9.9E-9 T 28-03-2018 IPR001650 Helicase, C-terminal CDW54_RS04910 ecae2d3b45d76b50ad97986cb6b6c314 802 Pfam PF04851 Type III restriction enzyme, res subunit 263 428 1.7E-18 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CDW54_RS04910 ecae2d3b45d76b50ad97986cb6b6c314 802 SMART SM00487 261 461 3.1E-25 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CDW54_RS04910 ecae2d3b45d76b50ad97986cb6b6c314 802 TIGRFAM TIGR00595 priA: primosomal protein N' 289 799 1.5E-210 T 28-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 CDW54_RS04910 ecae2d3b45d76b50ad97986cb6b6c314 802 Gene3D G3DSA:3.90.820.10 513 547 2.4E-5 T 28-03-2018 CDW54_RS04910 ecae2d3b45d76b50ad97986cb6b6c314 802 Gene3D G3DSA:3.40.50.300 181 500 1.2E-30 T 28-03-2018 CDW54_RS04910 ecae2d3b45d76b50ad97986cb6b6c314 802 SMART SM00490 564 661 1.8E-10 T 28-03-2018 IPR001650 Helicase, C-terminal CDW54_RS04910 ecae2d3b45d76b50ad97986cb6b6c314 802 Hamap MF_00983 Probable primosomal protein N' [priA]. 10 801 24.83 T 28-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 CDW54_RS04910 ecae2d3b45d76b50ad97986cb6b6c314 802 SUPERFAMILY SSF52540 530 708 1.15E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS01000 c03489f7bcba02fc537e2d1d4faa4f3e 287 Gene3D G3DSA:1.10.10.10 222 282 5.9E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS01000 c03489f7bcba02fc537e2d1d4faa4f3e 287 PIRSF PIRSF012524 1 284 6.7E-95 T 28-03-2018 IPR014464 Conserved virulence factor B CDW54_RS01000 c03489f7bcba02fc537e2d1d4faa4f3e 287 Gene3D G3DSA:2.40.50.140 65 221 6.2E-12 T 28-03-2018 CDW54_RS01000 c03489f7bcba02fc537e2d1d4faa4f3e 287 Pfam PF13509 S1 domain 10 62 2.9E-8 T 28-03-2018 CDW54_RS06915 71087f062c1129821545072ee2630ac8 319 Gene3D G3DSA:3.30.420.10 155 317 4.9E-22 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS06915 71087f062c1129821545072ee2630ac8 319 Pfam PF00665 Integrase core domain 170 265 7.8E-10 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CDW54_RS06915 71087f062c1129821545072ee2630ac8 319 SUPERFAMILY SSF53098 160 309 3.04E-21 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS06915 71087f062c1129821545072ee2630ac8 319 Gene3D G3DSA:1.10.10.60 6 68 1.1E-4 T 28-03-2018 CDW54_RS12365 5d8cec720ff5d2c8f25053f0a8e9b1b5 258 Gene3D G3DSA:2.40.30.10 1 96 1.3E-15 T 28-03-2018 CDW54_RS12365 5d8cec720ff5d2c8f25053f0a8e9b1b5 258 PIRSF PIRSF006816 1 258 4.0E-67 T 28-03-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 CDW54_RS12365 5d8cec720ff5d2c8f25053f0a8e9b1b5 258 Gene3D G3DSA:2.10.240.10 215 257 5.3E-15 T 28-03-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain CDW54_RS12365 5d8cec720ff5d2c8f25053f0a8e9b1b5 258 Gene3D G3DSA:3.40.50.80 100 214 5.4E-13 T 28-03-2018 CDW54_RS12365 5d8cec720ff5d2c8f25053f0a8e9b1b5 258 SUPERFAMILY SSF63380 2 98 3.23E-24 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CDW54_RS12365 5d8cec720ff5d2c8f25053f0a8e9b1b5 258 SUPERFAMILY SSF52343 93 257 7.07E-29 T 28-03-2018 CDW54_RS12365 5d8cec720ff5d2c8f25053f0a8e9b1b5 258 Hamap MF_01211 Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit [pyrK]. 3 258 35.238 T 28-03-2018 IPR023455 Dihydroorotate dehydrogenase electron transfer subunit CDW54_RS12365 5d8cec720ff5d2c8f25053f0a8e9b1b5 258 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 215 256 1.5E-15 T 28-03-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain CDW54_RS02910 96b07464a870e94e2e35a6a8b1dd3c2a 391 Pfam PF00155 Aminotransferase class I and II 58 383 1.5E-40 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CDW54_RS02910 96b07464a870e94e2e35a6a8b1dd3c2a 391 Gene3D G3DSA:3.90.1150.10 1 97 4.9E-14 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDW54_RS02910 96b07464a870e94e2e35a6a8b1dd3c2a 391 SUPERFAMILY SSF53383 2 388 9.84E-98 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDW54_RS02910 96b07464a870e94e2e35a6a8b1dd3c2a 391 Gene3D G3DSA:3.90.1150.10 276 391 5.3E-22 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDW54_RS02910 96b07464a870e94e2e35a6a8b1dd3c2a 391 TIGRFAM TIGR04350 C_S_lyase_PatB: putative C-S lyase 4 387 1.7E-132 T 28-03-2018 IPR027619 Putative C-S lyase KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 CDW54_RS02910 96b07464a870e94e2e35a6a8b1dd3c2a 391 Gene3D G3DSA:3.40.640.10 98 275 7.7E-29 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDW54_RS12580 5f7dbb8c48ae914769559cf885ce3c01 148 Gene3D G3DSA:1.10.10.10 1 87 3.3E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS12580 5f7dbb8c48ae914769559cf885ce3c01 148 Pfam PF01475 Ferric uptake regulator family 16 133 4.6E-38 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CDW54_RS12580 5f7dbb8c48ae914769559cf885ce3c01 148 SUPERFAMILY SSF46785 7 138 3.02E-42 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS08660 38579be561c09b7d64c9afcd8a664fa3 254 TIGRFAM TIGR00245 TIGR00245: TIGR00245 family protein 8 252 1.3E-77 T 28-03-2018 IPR005226 UPF0014 family CDW54_RS08660 38579be561c09b7d64c9afcd8a664fa3 254 Pfam PF03649 Uncharacterised protein family (UPF0014) 11 246 1.4E-76 T 28-03-2018 IPR005226 UPF0014 family CDW54_RS00385 8f6660f678132efca2cf74adf7541a56 511 SUPERFAMILY SSF52335 2 193 9.16E-68 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CDW54_RS00385 8f6660f678132efca2cf74adf7541a56 511 PIRSF PIRSF000414 1 511 7.9E-212 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CDW54_RS00385 8f6660f678132efca2cf74adf7541a56 511 SMART SM00851 13 128 1.4E-52 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CDW54_RS00385 8f6660f678132efca2cf74adf7541a56 511 Gene3D G3DSA:3.40.140.20 360 501 1.5E-50 T 28-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CDW54_RS00385 8f6660f678132efca2cf74adf7541a56 511 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 3 511 2.1E-224 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CDW54_RS00385 8f6660f678132efca2cf74adf7541a56 511 Pfam PF02142 MGS-like domain 13 127 6.4E-26 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CDW54_RS00385 8f6660f678132efca2cf74adf7541a56 511 SMART SM00798 133 446 1.9E-202 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CDW54_RS00385 8f6660f678132efca2cf74adf7541a56 511 Pfam PF01808 AICARFT/IMPCHase bienzyme 133 445 2.0E-121 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CDW54_RS00385 8f6660f678132efca2cf74adf7541a56 511 SUPERFAMILY SSF53927 206 511 2.11E-129 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CDW54_RS00385 8f6660f678132efca2cf74adf7541a56 511 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 1 511 44.2 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CDW54_RS00385 8f6660f678132efca2cf74adf7541a56 511 Gene3D G3DSA:3.40.50.1380 1 191 1.9E-72 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CDW54_RS00385 8f6660f678132efca2cf74adf7541a56 511 Gene3D G3DSA:3.40.140.20 211 359 5.9E-55 T 28-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CDW54_RS11480 7548570ab9e1c48a07488ee9f7861e6f 90 Pfam PF06961 Protein of unknown function (DUF1294) 17 71 1.2E-22 T 28-03-2018 IPR010718 Protein of unknown function DUF1294 CDW54_RS11480 7548570ab9e1c48a07488ee9f7861e6f 90 PIRSF PIRSF002599 3 88 2.1E-9 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 CDW54_RS00170 fafcfe1dd29e039374e5e8c81af6917d 791 SUPERFAMILY SSF52540 150 292 1.87E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS00170 fafcfe1dd29e039374e5e8c81af6917d 791 SUPERFAMILY SSF52540 344 396 1.87E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS00170 fafcfe1dd29e039374e5e8c81af6917d 791 Pfam PF13307 Helicase C-terminal domain 601 760 3.5E-37 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CDW54_RS00170 fafcfe1dd29e039374e5e8c81af6917d 791 SUPERFAMILY SSF52540 527 741 1.1E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS00170 fafcfe1dd29e039374e5e8c81af6917d 791 SUPERFAMILY SSF52540 208 259 1.1E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS00170 fafcfe1dd29e039374e5e8c81af6917d 791 SUPERFAMILY SSF52540 344 400 1.1E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS00170 fafcfe1dd29e039374e5e8c81af6917d 791 SMART SM00491 611 748 2.9E-10 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CDW54_RS00170 fafcfe1dd29e039374e5e8c81af6917d 791 Gene3D G3DSA:3.40.50.300 188 423 1.2E-22 T 28-03-2018 CDW54_RS00170 fafcfe1dd29e039374e5e8c81af6917d 791 Gene3D G3DSA:3.40.50.300 571 767 2.6E-8 T 28-03-2018 CDW54_RS00170 fafcfe1dd29e039374e5e8c81af6917d 791 Pfam PF00270 DEAD/DEAH box helicase 202 272 1.5E-5 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CDW54_RS00170 fafcfe1dd29e039374e5e8c81af6917d 791 SMART SM00488 182 429 1.5E-6 T 28-03-2018 IPR006554 Helicase-like, DEXD box c2 type GO:0004003|GO:0016818 CDW54_RS00170 fafcfe1dd29e039374e5e8c81af6917d 791 SMART SM00487 187 425 0.0053 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CDW54_RS00170 fafcfe1dd29e039374e5e8c81af6917d 791 Pfam PF06733 DEAD_2 278 398 1.2E-12 T 28-03-2018 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 CDW54_RS11210 b86e79b586123792d9848f5385f2251c 457 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 438 448 - T 28-03-2018 IPR030391 RNA methyltransferase TrmA, conserved site CDW54_RS11210 b86e79b586123792d9848f5385f2251c 457 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 386 417 - T 28-03-2018 IPR030390 RNA methyltransferase TrmA, active site CDW54_RS11210 b86e79b586123792d9848f5385f2251c 457 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 92 448 5.3E-27 T 28-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 CDW54_RS11210 b86e79b586123792d9848f5385f2251c 457 Gene3D G3DSA:3.40.50.150 79 454 1.4E-50 T 28-03-2018 CDW54_RS11210 b86e79b586123792d9848f5385f2251c 457 Gene3D G3DSA:2.40.50.140 1 78 1.4E-18 T 28-03-2018 CDW54_RS11210 b86e79b586123792d9848f5385f2251c 457 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 20 448 1.2E-138 T 28-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 CDW54_RS11210 b86e79b586123792d9848f5385f2251c 457 SUPERFAMILY SSF50249 4 62 6.85E-15 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDW54_RS11210 b86e79b586123792d9848f5385f2251c 457 Pfam PF01938 TRAM domain 9 62 2.0E-9 T 28-03-2018 IPR002792 TRAM domain CDW54_RS11210 b86e79b586123792d9848f5385f2251c 457 SUPERFAMILY SSF53335 82 455 1.29E-77 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDW54_RS03030 eb1c289b5a6386ac4e6ce35ad2052211 500 Pfam PF02687 FtsX-like permease family 358 494 8.0E-12 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CDW54_RS03530 413e9bc2aca4b52950d648c0ebc5c86a 386 SUPERFAMILY SSF51735 82 265 2.9E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS03530 413e9bc2aca4b52950d648c0ebc5c86a 386 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 19 296 9.2E-16 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CDW54_RS03530 413e9bc2aca4b52950d648c0ebc5c86a 386 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 98 263 9.4E-40 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CDW54_RS03530 413e9bc2aca4b52950d648c0ebc5c86a 386 Gene3D G3DSA:3.40.50.720 2 97 1.5E-16 T 28-03-2018 CDW54_RS03530 413e9bc2aca4b52950d648c0ebc5c86a 386 SUPERFAMILY SSF52283 2 109 8.72E-16 T 28-03-2018 CDW54_RS03530 413e9bc2aca4b52950d648c0ebc5c86a 386 Gene3D G3DSA:3.40.50.720 98 267 5.4E-38 T 28-03-2018 CDW54_RS03530 413e9bc2aca4b52950d648c0ebc5c86a 386 Gene3D G3DSA:3.30.70.260 308 385 5.6E-9 T 28-03-2018 CDW54_RS03530 413e9bc2aca4b52950d648c0ebc5c86a 386 SUPERFAMILY SSF55021 302 380 1.34E-8 T 28-03-2018 CDW54_RS03530 413e9bc2aca4b52950d648c0ebc5c86a 386 Pfam PF13291 ACT domain 309 378 1.3E-7 T 28-03-2018 IPR002912 ACT domain CDW54_RS12485 23429f6cf9f02deee4690178cc24de7b 317 SUPERFAMILY SSF51735 1 312 9.61E-57 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS12485 23429f6cf9f02deee4690178cc24de7b 317 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 239 3.7E-28 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CDW54_RS12485 23429f6cf9f02deee4690178cc24de7b 317 Gene3D G3DSA:3.40.50.720 1 316 3.1E-40 T 28-03-2018 CDW54_RS06375 741c4e852fdd4c19c5eaf6d963a7efd8 186 Hamap MF_00528 Septum formation protein Maf [maf]. 2 186 28.384 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 CDW54_RS06375 741c4e852fdd4c19c5eaf6d963a7efd8 186 Gene3D G3DSA:3.90.950.10 1 186 4.6E-65 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CDW54_RS06375 741c4e852fdd4c19c5eaf6d963a7efd8 186 SUPERFAMILY SSF52972 1 183 2.62E-59 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CDW54_RS06375 741c4e852fdd4c19c5eaf6d963a7efd8 186 Pfam PF02545 Maf-like protein 2 184 6.5E-55 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 CDW54_RS06375 741c4e852fdd4c19c5eaf6d963a7efd8 186 PIRSF PIRSF006305 1 186 1.0E-56 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 CDW54_RS06375 741c4e852fdd4c19c5eaf6d963a7efd8 186 TIGRFAM TIGR00172 maf: septum formation protein Maf 2 183 1.3E-50 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 CDW54_RS02430 93aa85c4f1d6775631a6fa21b8bc70f7 87 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 81 28.481 T 28-03-2018 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS02430 93aa85c4f1d6775631a6fa21b8bc70f7 87 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 80 1.6E-19 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS02430 93aa85c4f1d6775631a6fa21b8bc70f7 87 SUPERFAMILY SSF143800 1 80 6.28E-24 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS02430 93aa85c4f1d6775631a6fa21b8bc70f7 87 PRINTS PR01249 Ribosomal protein L31 signature 45 60 1.5E-19 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS02430 93aa85c4f1d6775631a6fa21b8bc70f7 87 PRINTS PR01249 Ribosomal protein L31 signature 60 78 1.5E-19 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS02430 93aa85c4f1d6775631a6fa21b8bc70f7 87 PRINTS PR01249 Ribosomal protein L31 signature 2 19 1.5E-19 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS02430 93aa85c4f1d6775631a6fa21b8bc70f7 87 Pfam PF01197 Ribosomal protein L31 1 79 6.7E-29 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS02430 93aa85c4f1d6775631a6fa21b8bc70f7 87 ProSitePatterns PS01143 Ribosomal protein L31 signature. 49 70 - T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS00730 231c4534f623b33d15cd8fce5da37f8e 212 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 4 201 1.3E-56 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CDW54_RS00730 231c4534f623b33d15cd8fce5da37f8e 212 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 5 202 19.839 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CDW54_RS00730 231c4534f623b33d15cd8fce5da37f8e 212 SMART SM01207 8 194 7.1E-83 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CDW54_RS00730 231c4534f623b33d15cd8fce5da37f8e 212 Pfam PF02660 Glycerol-3-phosphate acyltransferase 9 193 3.4E-53 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CDW54_RS09290 79e2b08cedb9268fe23e54cc8306b29a 546 PRINTS PR00072 Malic enzyme signature 287 303 6.9E-68 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CDW54_RS09290 79e2b08cedb9268fe23e54cc8306b29a 546 PRINTS PR00072 Malic enzyme signature 74 98 6.9E-68 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CDW54_RS09290 79e2b08cedb9268fe23e54cc8306b29a 546 PRINTS PR00072 Malic enzyme signature 231 249 6.9E-68 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CDW54_RS09290 79e2b08cedb9268fe23e54cc8306b29a 546 PRINTS PR00072 Malic enzyme signature 394 410 6.9E-68 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CDW54_RS09290 79e2b08cedb9268fe23e54cc8306b29a 546 PRINTS PR00072 Malic enzyme signature 172 194 6.9E-68 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CDW54_RS09290 79e2b08cedb9268fe23e54cc8306b29a 546 PRINTS PR00072 Malic enzyme signature 136 165 6.9E-68 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CDW54_RS09290 79e2b08cedb9268fe23e54cc8306b29a 546 PRINTS PR00072 Malic enzyme signature 256 272 6.9E-68 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CDW54_RS09290 79e2b08cedb9268fe23e54cc8306b29a 546 Pfam PF03949 Malic enzyme, NAD binding domain 260 515 9.3E-95 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CDW54_RS09290 79e2b08cedb9268fe23e54cc8306b29a 546 PIRSF PIRSF000106 1 546 5.6E-207 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CDW54_RS09290 79e2b08cedb9268fe23e54cc8306b29a 546 Gene3D G3DSA:3.40.50.10380 2 257 4.5E-96 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CDW54_RS09290 79e2b08cedb9268fe23e54cc8306b29a 546 SUPERFAMILY SSF51735 260 543 2.02E-83 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS09290 79e2b08cedb9268fe23e54cc8306b29a 546 Gene3D G3DSA:3.40.50.720 258 545 2.4E-95 T 28-03-2018 CDW54_RS09290 79e2b08cedb9268fe23e54cc8306b29a 546 ProSitePatterns PS00331 Malic enzymes signature. 256 272 - T 28-03-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 CDW54_RS09290 79e2b08cedb9268fe23e54cc8306b29a 546 Pfam PF00390 Malic enzyme, N-terminal domain 69 249 5.0E-66 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CDW54_RS09290 79e2b08cedb9268fe23e54cc8306b29a 546 SMART SM01274 68 250 2.8E-84 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CDW54_RS09290 79e2b08cedb9268fe23e54cc8306b29a 546 SMART SM00919 260 516 2.2E-108 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CDW54_RS09290 79e2b08cedb9268fe23e54cc8306b29a 546 SUPERFAMILY SSF53223 2 259 2.23E-96 T 28-03-2018 CDW54_RS06695 4a351afc149d7b86d9cdb85cde9ddf1d 865 Gene3D G3DSA:3.40.50.1970 438 649 2.3E-52 T 28-03-2018 CDW54_RS06695 4a351afc149d7b86d9cdb85cde9ddf1d 865 Gene3D G3DSA:3.40.309.10 242 413 2.1E-27 T 28-03-2018 CDW54_RS06695 4a351afc149d7b86d9cdb85cde9ddf1d 865 PIRSF PIRSF000111 2 865 0.0 T 28-03-2018 IPR012079 Bifunctional aldehyde-alcohol dehydrogenase GO:0004022|GO:0006066|GO:0008774|GO:0015976|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 CDW54_RS06695 4a351afc149d7b86d9cdb85cde9ddf1d 865 Gene3D G3DSA:1.20.1090.10 650 865 1.2E-62 T 28-03-2018 CDW54_RS06695 4a351afc149d7b86d9cdb85cde9ddf1d 865 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 724 744 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CDW54_RS06695 4a351afc149d7b86d9cdb85cde9ddf1d 865 SUPERFAMILY SSF56796 456 865 7.46E-119 T 28-03-2018 CDW54_RS06695 4a351afc149d7b86d9cdb85cde9ddf1d 865 Gene3D G3DSA:3.40.605.10 8 241 1.7E-29 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CDW54_RS06695 4a351afc149d7b86d9cdb85cde9ddf1d 865 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 638 666 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CDW54_RS06695 4a351afc149d7b86d9cdb85cde9ddf1d 865 SUPERFAMILY SSF53720 17 461 2.36E-82 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CDW54_RS06695 4a351afc149d7b86d9cdb85cde9ddf1d 865 Pfam PF00171 Aldehyde dehydrogenase family 17 410 8.6E-25 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CDW54_RS06695 4a351afc149d7b86d9cdb85cde9ddf1d 865 Pfam PF00465 Iron-containing alcohol dehydrogenase 465 852 3.4E-118 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CDW54_RS04440 83649c99b793fb39cbb6fb24f94e8c96 485 Pfam PF13416 Bacterial extracellular solute-binding protein 63 342 4.1E-15 T 28-03-2018 CDW54_RS04440 83649c99b793fb39cbb6fb24f94e8c96 485 Gene3D G3DSA:3.40.190.10 28 271 9.1E-25 T 28-03-2018 CDW54_RS04440 83649c99b793fb39cbb6fb24f94e8c96 485 Gene3D G3DSA:3.40.190.10 279 406 3.5E-5 T 28-03-2018 CDW54_RS04440 83649c99b793fb39cbb6fb24f94e8c96 485 SUPERFAMILY SSF53850 21 484 4.56E-88 T 28-03-2018 CDW54_RS04440 83649c99b793fb39cbb6fb24f94e8c96 485 Pfam PF12010 Domain of unknown function (DUF3502) 352 483 2.7E-39 T 28-03-2018 IPR022627 Domain of unknown function DUF3502 CDW54_RS09535 308be6f16d05e3de454772dd40b548c2 168 SUPERFAMILY SSF88659 105 168 2.24E-13 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDW54_RS09535 308be6f16d05e3de454772dd40b548c2 168 SUPERFAMILY SSF88946 17 102 3.22E-16 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDW54_RS09535 308be6f16d05e3de454772dd40b548c2 168 Pfam PF08281 Sigma-70, region 4 112 163 3.5E-11 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDW54_RS09535 308be6f16d05e3de454772dd40b548c2 168 Gene3D G3DSA:1.10.1740.10 8 107 1.4E-16 T 28-03-2018 CDW54_RS09535 308be6f16d05e3de454772dd40b548c2 168 Pfam PF04542 Sigma-70 region 2 22 90 2.6E-10 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDW54_RS09535 308be6f16d05e3de454772dd40b548c2 168 Gene3D G3DSA:1.10.10.10 108 168 1.6E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS09535 308be6f16d05e3de454772dd40b548c2 168 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 18 167 6.9E-23 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDW54_RS11305 06101b19fc52b11207374031941c3519 576 SUPERFAMILY SSF55874 430 568 9.3E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS11305 06101b19fc52b11207374031941c3519 576 Gene3D G3DSA:3.30.565.10 310 569 1.9E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS11305 06101b19fc52b11207374031941c3519 576 PRINTS PR00344 Bacterial sensor protein C-terminal signature 554 567 8.9E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDW54_RS11305 06101b19fc52b11207374031941c3519 576 PRINTS PR00344 Bacterial sensor protein C-terminal signature 527 545 8.9E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDW54_RS11305 06101b19fc52b11207374031941c3519 576 PRINTS PR00344 Bacterial sensor protein C-terminal signature 505 519 8.9E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDW54_RS11305 06101b19fc52b11207374031941c3519 576 Gene3D G3DSA:3.30.450.20 49 213 0.0032 T 28-03-2018 CDW54_RS11305 06101b19fc52b11207374031941c3519 576 Pfam PF06580 Histidine kinase 376 454 1.1E-21 T 28-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 CDW54_RS02090 f71a51d92b79b3b5e6cfbe26f5248b55 143 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 143 58.357 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 CDW54_RS02090 f71a51d92b79b3b5e6cfbe26f5248b55 143 SUPERFAMILY SSF89447 1 136 6.7E-52 T 28-03-2018 CDW54_RS02090 f71a51d92b79b3b5e6cfbe26f5248b55 143 Pfam PF02381 MraZ protein, putative antitoxin-like 1 70 6.1E-24 T 28-03-2018 IPR020603 MraZ domain CDW54_RS02090 f71a51d92b79b3b5e6cfbe26f5248b55 143 Pfam PF02381 MraZ protein, putative antitoxin-like 72 141 4.0E-27 T 28-03-2018 IPR020603 MraZ domain CDW54_RS02090 f71a51d92b79b3b5e6cfbe26f5248b55 143 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 1 142 1.2E-55 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 CDW54_RS02090 f71a51d92b79b3b5e6cfbe26f5248b55 143 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 138 9.0E-78 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 CDW54_RS02090 f71a51d92b79b3b5e6cfbe26f5248b55 143 Gene3D G3DSA:2.10.260.10 73 122 1.8E-7 T 28-03-2018 CDW54_RS02090 f71a51d92b79b3b5e6cfbe26f5248b55 143 Gene3D G3DSA:2.10.260.10 1 64 1.7E-6 T 28-03-2018 CDW54_RS12155 7648157027af0f83b06145ff776a07f2 510 Gene3D G3DSA:3.40.50.980 11 172 8.0E-18 T 28-03-2018 CDW54_RS12155 7648157027af0f83b06145ff776a07f2 510 ProSitePatterns PS00455 Putative AMP-binding domain signature. 167 178 - T 28-03-2018 IPR020845 AMP-binding, conserved site CDW54_RS12155 7648157027af0f83b06145ff776a07f2 510 Gene3D G3DSA:3.40.50.980 173 328 3.3E-14 T 28-03-2018 CDW54_RS12155 7648157027af0f83b06145ff776a07f2 510 Gene3D G3DSA:2.30.38.10 329 412 1.6E-9 T 28-03-2018 CDW54_RS12155 7648157027af0f83b06145ff776a07f2 510 SUPERFAMILY SSF56801 6 506 5.49E-58 T 28-03-2018 CDW54_RS12155 7648157027af0f83b06145ff776a07f2 510 Pfam PF00501 AMP-binding enzyme 17 418 1.0E-35 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CDW54_RS07115 1e88dd751fad02a83ebca741ccba3268 377 SUPERFAMILY SSF51735 155 338 6.62E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS07115 1e88dd751fad02a83ebca741ccba3268 377 Pfam PF00107 Zinc-binding dehydrogenase 188 255 6.2E-10 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CDW54_RS07115 1e88dd751fad02a83ebca741ccba3268 377 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CDW54_RS07115 1e88dd751fad02a83ebca741ccba3268 377 Pfam PF13823 Alcohol dehydrogenase GroES-associated 1 23 7.2E-11 T 28-03-2018 IPR027399 Alcohol dehydrogenase GroES-associated CDW54_RS07115 1e88dd751fad02a83ebca741ccba3268 377 Gene3D G3DSA:3.90.180.10 1 177 2.5E-48 T 28-03-2018 CDW54_RS07115 1e88dd751fad02a83ebca741ccba3268 377 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 138 1.8E-28 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CDW54_RS07115 1e88dd751fad02a83ebca741ccba3268 377 SUPERFAMILY SSF50129 1 176 1.73E-60 T 28-03-2018 IPR011032 GroES-like CDW54_RS07115 1e88dd751fad02a83ebca741ccba3268 377 Gene3D G3DSA:3.40.50.720 178 332 4.9E-23 T 28-03-2018 CDW54_RS09180 aafefda4a97cf88a6c9faaa3c16df823 275 Gene3D G3DSA:1.10.3720.10 2 254 8.4E-39 T 28-03-2018 CDW54_RS09180 aafefda4a97cf88a6c9faaa3c16df823 275 SUPERFAMILY SSF161098 4 252 6.8E-50 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS09180 aafefda4a97cf88a6c9faaa3c16df823 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 77 247 2.8E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS08510 468557ed55c2d9fc7fc67ec56da7a6d4 81 SUPERFAMILY SSF47413 12 80 4.5E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDW54_RS08510 468557ed55c2d9fc7fc67ec56da7a6d4 81 Pfam PF12844 Helix-turn-helix domain 17 81 1.4E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDW54_RS08510 468557ed55c2d9fc7fc67ec56da7a6d4 81 SMART SM00530 19 79 6.5E-4 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDW54_RS08510 468557ed55c2d9fc7fc67ec56da7a6d4 81 Gene3D G3DSA:1.10.260.40 5 81 7.9E-14 T 28-03-2018 CDW54_RS01170 bebb1f8b0bf4995f965aabcde23dd613 250 Gene3D G3DSA:3.40.225.10 8 219 7.3E-38 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CDW54_RS01170 bebb1f8b0bf4995f965aabcde23dd613 250 SMART SM01007 13 206 1.2E-17 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CDW54_RS01170 bebb1f8b0bf4995f965aabcde23dd613 250 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 13 205 2.2E-25 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CDW54_RS01170 bebb1f8b0bf4995f965aabcde23dd613 250 SUPERFAMILY SSF53639 7 207 9.03E-33 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CDW54_RS08310 6d4d5cb90d47b35a8226b1651a881dff 118 Gene3D G3DSA:3.40.30.10 1 117 1.1E-34 T 28-03-2018 CDW54_RS08310 6d4d5cb90d47b35a8226b1651a881dff 118 SUPERFAMILY SSF52833 3 115 2.31E-30 T 28-03-2018 IPR012336 Thioredoxin-like fold CDW54_RS08310 6d4d5cb90d47b35a8226b1651a881dff 118 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 3 114 7.1E-31 T 28-03-2018 IPR006504 Transcriptional regulator Spx/MgsR CDW54_RS08310 6d4d5cb90d47b35a8226b1651a881dff 118 Pfam PF03960 ArsC family 5 114 7.5E-12 T 28-03-2018 IPR006660 Arsenate reductase-like CDW54_RS04345 5329f1275d2adb3b4b0623514e4c03b8 330 Gene3D G3DSA:3.40.50.2300 173 310 6.9E-42 T 28-03-2018 CDW54_RS04345 5329f1275d2adb3b4b0623514e4c03b8 330 Gene3D G3DSA:3.40.50.2300 54 172 8.5E-20 T 28-03-2018 CDW54_RS04345 5329f1275d2adb3b4b0623514e4c03b8 330 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 6.2E-6 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS04345 5329f1275d2adb3b4b0623514e4c03b8 330 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 6.2E-6 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS04345 5329f1275d2adb3b4b0623514e4c03b8 330 SUPERFAMILY SSF53822 108 328 1.77E-63 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CDW54_RS04345 5329f1275d2adb3b4b0623514e4c03b8 330 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 28-03-2018 CDW54_RS04345 5329f1275d2adb3b4b0623514e4c03b8 330 SUPERFAMILY SSF47413 1 58 3.66E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDW54_RS04345 5329f1275d2adb3b4b0623514e4c03b8 330 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 1.0E-18 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS04345 5329f1275d2adb3b4b0623514e4c03b8 330 Pfam PF13377 Periplasmic binding protein-like domain 167 326 4.8E-38 T 28-03-2018 CDW54_RS04345 5329f1275d2adb3b4b0623514e4c03b8 330 Gene3D G3DSA:1.10.260.40 2 53 6.3E-21 T 28-03-2018 CDW54_RS04345 5329f1275d2adb3b4b0623514e4c03b8 330 SMART SM00354 1 71 7.1E-25 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS08155 0ea5f969ae326f03a15377fa93d31842 458 PIRSF PIRSF006060 10 458 3.6E-90 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CDW54_RS08155 0ea5f969ae326f03a15377fa93d31842 458 Pfam PF13520 Amino acid permease 22 424 2.1E-58 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CDW54_RS04340 fe8ed7d9cf6ef05708260a4446ba1451 732 Gene3D G3DSA:1.10.10.60 684 731 6.0E-13 T 28-03-2018 CDW54_RS04340 fe8ed7d9cf6ef05708260a4446ba1451 732 SUPERFAMILY SSF46689 682 731 9.86E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDW54_RS04340 fe8ed7d9cf6ef05708260a4446ba1451 732 Gene3D G3DSA:2.60.120.10 347 683 3.8E-12 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CDW54_RS04340 fe8ed7d9cf6ef05708260a4446ba1451 732 SUPERFAMILY SSF46689 633 679 2.33E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDW54_RS04340 fe8ed7d9cf6ef05708260a4446ba1451 732 SMART SM00342 645 728 4.8E-31 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CDW54_RS04340 fe8ed7d9cf6ef05708260a4446ba1451 732 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 682 724 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CDW54_RS04340 fe8ed7d9cf6ef05708260a4446ba1451 732 Pfam PF12833 Helix-turn-helix domain 651 729 6.8E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CDW54_RS12605 d50ab64609c006a8e5afea7050a8be0a 210 Pfam PF01726 LexA DNA binding domain 10 69 1.4E-24 T 28-03-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 CDW54_RS12605 d50ab64609c006a8e5afea7050a8be0a 210 Gene3D G3DSA:1.10.10.10 4 83 8.4E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS12605 d50ab64609c006a8e5afea7050a8be0a 210 SUPERFAMILY SSF46785 10 74 9.62E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS12605 d50ab64609c006a8e5afea7050a8be0a 210 Hamap MF_00015 LexA repressor [lexA]. 7 208 32.343 T 28-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 CDW54_RS12605 d50ab64609c006a8e5afea7050a8be0a 210 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 134 145 6.3E-8 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CDW54_RS12605 d50ab64609c006a8e5afea7050a8be0a 210 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 163 175 6.3E-8 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CDW54_RS12605 d50ab64609c006a8e5afea7050a8be0a 210 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 123 133 6.3E-8 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CDW54_RS12605 d50ab64609c006a8e5afea7050a8be0a 210 Pfam PF00717 Peptidase S24-like 126 190 3.3E-15 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CDW54_RS12605 d50ab64609c006a8e5afea7050a8be0a 210 Gene3D G3DSA:2.10.109.10 91 208 2.4E-24 T 28-03-2018 CDW54_RS12605 d50ab64609c006a8e5afea7050a8be0a 210 SUPERFAMILY SSF51306 85 206 5.76E-34 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CDW54_RS12605 d50ab64609c006a8e5afea7050a8be0a 210 TIGRFAM TIGR00498 lexA: repressor LexA 10 207 4.1E-68 T 28-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 CDW54_RS03380 ac47642a36fff29521ab6f3ebd9893e0 189 Gene3D G3DSA:2.10.109.10 20 189 1.9E-41 T 28-03-2018 CDW54_RS03380 ac47642a36fff29521ab6f3ebd9893e0 189 ProSitePatterns PS00761 Signal peptidases I signature 3. 148 161 - T 28-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 CDW54_RS03380 ac47642a36fff29521ab6f3ebd9893e0 189 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 24 40 3.2E-20 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CDW54_RS03380 ac47642a36fff29521ab6f3ebd9893e0 189 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 72 84 3.2E-20 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CDW54_RS03380 ac47642a36fff29521ab6f3ebd9893e0 189 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 143 162 3.2E-20 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CDW54_RS03380 ac47642a36fff29521ab6f3ebd9893e0 189 Pfam PF00717 Peptidase S24-like 30 96 1.0E-16 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CDW54_RS03380 ac47642a36fff29521ab6f3ebd9893e0 189 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 10 183 8.6E-49 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CDW54_RS03380 ac47642a36fff29521ab6f3ebd9893e0 189 ProSitePatterns PS00760 Signal peptidases I lysine active site. 74 86 - T 28-03-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 CDW54_RS03380 ac47642a36fff29521ab6f3ebd9893e0 189 SUPERFAMILY SSF51306 22 188 2.62E-51 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CDW54_RS03380 ac47642a36fff29521ab6f3ebd9893e0 189 ProSitePatterns PS00501 Signal peptidases I serine active site. 33 40 - T 28-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 CDW54_RS02835 6ecd39dd69f3936112dd987f249dc683 720 Gene3D G3DSA:2.70.70.10 557 720 4.8E-49 T 28-03-2018 CDW54_RS02835 6ecd39dd69f3936112dd987f249dc683 720 SUPERFAMILY SSF55604 470 543 1.96E-18 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CDW54_RS02835 6ecd39dd69f3936112dd987f249dc683 720 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 482 499 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CDW54_RS02835 6ecd39dd69f3936112dd987f249dc683 720 Gene3D G3DSA:3.30.1360.60 467 543 5.3E-23 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CDW54_RS02835 6ecd39dd69f3936112dd987f249dc683 720 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 577 694 1.2E-38 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CDW54_RS02835 6ecd39dd69f3936112dd987f249dc683 720 Pfam PF02378 Phosphotransferase system, EIIC 14 378 6.1E-54 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CDW54_RS02835 6ecd39dd69f3936112dd987f249dc683 720 Pfam PF00367 phosphotransferase system, EIIB 472 503 3.6E-14 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CDW54_RS02835 6ecd39dd69f3936112dd987f249dc683 720 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 574 696 1.0E-45 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CDW54_RS02835 6ecd39dd69f3936112dd987f249dc683 720 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 637 649 - T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CDW54_RS02835 6ecd39dd69f3936112dd987f249dc683 720 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 438 529 1.0E-16 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CDW54_RS02835 6ecd39dd69f3936112dd987f249dc683 720 SUPERFAMILY SSF51261 573 708 8.72E-46 T 28-03-2018 IPR011055 Duplicated hybrid motif CDW54_RS02835 6ecd39dd69f3936112dd987f249dc683 720 TIGRFAM TIGR02003 PTS-II-BC-unk1: PTS system, IIBC component 3 545 6.2E-290 T 28-03-2018 IPR011300 Phosphotransferase system, IIBC component KEGG: 00010+2.7.1.199|KEGG: 00520+2.7.1.199|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 CDW54_RS04200 6653ed97b586f209045766056145f044 403 PIRSF PIRSF037259 1 403 2.5E-113 T 28-03-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 CDW54_RS04200 6653ed97b586f209045766056145f044 403 Pfam PF05975 Bacterial ABC transporter protein EcsB 3 383 3.7E-126 T 28-03-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 CDW54_RS07320 e156b9062ce0820f3af04d8f55431e84 437 Pfam PF00860 Permease family 21 394 1.6E-40 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CDW54_RS07320 e156b9062ce0820f3af04d8f55431e84 437 PIRSF PIRSF005353 1 436 2.5E-161 T 28-03-2018 IPR026033 Purine permease PbuG-like CDW54_RS08185 8718abeb25b948319b50413f0b2c71fa 181 SUPERFAMILY SSF52499 3 179 6.28E-49 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CDW54_RS08185 8718abeb25b948319b50413f0b2c71fa 181 Pfam PF00857 Isochorismatase family 3 174 1.9E-34 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CDW54_RS08185 8718abeb25b948319b50413f0b2c71fa 181 Gene3D G3DSA:3.40.50.850 1 181 4.2E-46 T 28-03-2018 CDW54_RS08960 1072afed6805467b1545252b8629cb03 257 Pfam PF12679 ABC-2 family transporter protein 4 256 1.4E-15 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CDW54_RS00195 96372d1f67db7645222bd47f6e5c2716 151 Pfam PF04284 Protein of unknown function (DUF441) 5 144 1.4E-49 T 28-03-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame CDW54_RS00195 96372d1f67db7645222bd47f6e5c2716 151 Hamap MF_01874 UPF0756 membrane protein YeaL [yeaL]. 1 147 19.325 T 28-03-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame CDW54_RS00195 96372d1f67db7645222bd47f6e5c2716 151 ProDom PD021096 MEMBRANE YEAL PRECURSOR SIGNAL PROTEIN TRANSMEMBRANE YTWI HI1074 INTEGRAL SPANNING 5 129 4.0E-54 T 28-03-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame CDW54_RS08060 b0cfc229ed6c50371bcf02eaa8cf853c 500 Gene3D G3DSA:3.40.120.10 3 171 7.1E-34 T 28-03-2018 CDW54_RS08060 b0cfc229ed6c50371bcf02eaa8cf853c 500 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 167 273 3.1E-21 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDW54_RS08060 b0cfc229ed6c50371bcf02eaa8cf853c 500 SUPERFAMILY SSF53738 278 391 5.49E-18 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDW54_RS08060 b0cfc229ed6c50371bcf02eaa8cf853c 500 SUPERFAMILY SSF53738 12 196 1.77E-28 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDW54_RS08060 b0cfc229ed6c50371bcf02eaa8cf853c 500 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 110 124 6.0E-19 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDW54_RS08060 b0cfc229ed6c50371bcf02eaa8cf853c 500 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 224 237 6.0E-19 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDW54_RS08060 b0cfc229ed6c50371bcf02eaa8cf853c 500 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 189 208 6.0E-19 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDW54_RS08060 b0cfc229ed6c50371bcf02eaa8cf853c 500 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 253 268 6.0E-19 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDW54_RS08060 b0cfc229ed6c50371bcf02eaa8cf853c 500 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 278 392 6.8E-13 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDW54_RS08060 b0cfc229ed6c50371bcf02eaa8cf853c 500 SUPERFAMILY SSF53738 165 276 2.75E-24 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDW54_RS08060 b0cfc229ed6c50371bcf02eaa8cf853c 500 Gene3D G3DSA:3.30.310.50 396 497 2.3E-9 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDW54_RS08060 b0cfc229ed6c50371bcf02eaa8cf853c 500 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 7 145 2.7E-30 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDW54_RS08060 b0cfc229ed6c50371bcf02eaa8cf853c 500 Gene3D G3DSA:3.40.120.10 172 279 3.4E-26 T 28-03-2018 CDW54_RS08060 b0cfc229ed6c50371bcf02eaa8cf853c 500 Gene3D G3DSA:3.40.120.10 280 392 3.0E-20 T 28-03-2018 CDW54_RS07680 c35f783e656c7fe5a9d0df136744b2f0 202 Pfam PF08006 Protein of unknown function (DUF1700) 2 187 4.4E-14 T 28-03-2018 IPR012963 Protein of unknown function DUF1700 CDW54_RS07835 9195471555c662917ad691394e3c03b1 136 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 2 114 2.0E-37 T 28-03-2018 IPR006504 Transcriptional regulator Spx/MgsR CDW54_RS07835 9195471555c662917ad691394e3c03b1 136 Gene3D G3DSA:3.40.30.10 1 125 5.9E-35 T 28-03-2018 CDW54_RS07835 9195471555c662917ad691394e3c03b1 136 SUPERFAMILY SSF52833 1 119 3.21E-35 T 28-03-2018 IPR012336 Thioredoxin-like fold CDW54_RS07835 9195471555c662917ad691394e3c03b1 136 Pfam PF03960 ArsC family 5 113 1.9E-21 T 28-03-2018 IPR006660 Arsenate reductase-like CDW54_RS09455 b0f5d31a9dd4875d0d61c661f2a6cba7 103 Hamap MF_00312 V-type ATP synthase subunit F [atpF]. 3 103 17.702 T 28-03-2018 IPR022944 ATPase, V1 complex, subunit F, bacterial/archaeal CDW54_RS09455 b0f5d31a9dd4875d0d61c661f2a6cba7 103 SUPERFAMILY SSF159468 5 102 1.57E-25 T 28-03-2018 IPR008218 ATPase, V1 complex, subunit F GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CDW54_RS09455 b0f5d31a9dd4875d0d61c661f2a6cba7 103 Pfam PF01990 ATP synthase (F/14-kDa) subunit 5 94 2.5E-24 T 28-03-2018 IPR008218 ATPase, V1 complex, subunit F GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CDW54_RS09455 b0f5d31a9dd4875d0d61c661f2a6cba7 103 Gene3D G3DSA:3.40.50.10580 2 103 5.7E-27 T 28-03-2018 IPR008218 ATPase, V1 complex, subunit F GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CDW54_RS08930 0f9c298924d764185fa4985a21403db2 175 SMART SM00855 1 149 7.0E-22 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CDW54_RS08930 0f9c298924d764185fa4985a21403db2 175 PIRSF PIRSF000709 1 169 4.1E-19 T 28-03-2018 CDW54_RS08930 0f9c298924d764185fa4985a21403db2 175 SUPERFAMILY SSF53254 2 175 1.96E-50 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CDW54_RS08930 0f9c298924d764185fa4985a21403db2 175 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 2 173 2.9E-47 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CDW54_RS08930 0f9c298924d764185fa4985a21403db2 175 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 4 13 - T 28-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CDW54_RS08930 0f9c298924d764185fa4985a21403db2 175 Gene3D G3DSA:3.40.50.1240 1 175 4.9E-48 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CDW54_RS12550 739e7c2aa7d1cc1de99d15c66749b524 225 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 189 205 3.9E-7 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CDW54_RS12550 739e7c2aa7d1cc1de99d15c66749b524 225 Pfam PF00633 Helix-hairpin-helix motif 100 127 1.1E-10 T 28-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 CDW54_RS12550 739e7c2aa7d1cc1de99d15c66749b524 225 SMART SM00478 39 187 1.5E-61 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CDW54_RS12550 739e7c2aa7d1cc1de99d15c66749b524 225 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 189 205 - T 28-03-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CDW54_RS12550 739e7c2aa7d1cc1de99d15c66749b524 225 SMART SM00525 188 208 6.2E-4 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CDW54_RS12550 739e7c2aa7d1cc1de99d15c66749b524 225 Gene3D G3DSA:1.10.1670.10 119 223 3.9E-33 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CDW54_RS12550 739e7c2aa7d1cc1de99d15c66749b524 225 Gene3D G3DSA:1.10.340.30 3 118 7.0E-28 T 28-03-2018 CDW54_RS12550 739e7c2aa7d1cc1de99d15c66749b524 225 SUPERFAMILY SSF48150 1 207 1.54E-74 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CDW54_RS12550 739e7c2aa7d1cc1de99d15c66749b524 225 PIRSF PIRSF001435 1 213 1.6E-58 T 28-03-2018 CDW54_RS12550 739e7c2aa7d1cc1de99d15c66749b524 225 ProSitePatterns PS01155 Endonuclease III family signature. 103 132 - T 28-03-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 CDW54_RS12550 739e7c2aa7d1cc1de99d15c66749b524 225 Hamap MF_00942 Endonuclease III [nth]. 1 211 39.454 T 28-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 CDW54_RS12550 739e7c2aa7d1cc1de99d15c66749b524 225 TIGRFAM TIGR01083 nth: endonuclease III 4 196 1.7E-82 T 28-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 CDW54_RS12550 739e7c2aa7d1cc1de99d15c66749b524 225 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 35 170 3.1E-23 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CDW54_RS05090 0cefa55223ac2f18ec4727c6bed0655a 178 SUPERFAMILY SSF51161 9 170 7.49E-56 T 28-03-2018 IPR011004 Trimeric LpxA-like CDW54_RS05090 0cefa55223ac2f18ec4727c6bed0655a 178 Gene3D G3DSA:2.160.10.10 52 178 3.5E-35 T 28-03-2018 CDW54_RS05090 0cefa55223ac2f18ec4727c6bed0655a 178 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 7 165 5.5E-72 T 28-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 CDW54_RS05090 0cefa55223ac2f18ec4727c6bed0655a 178 Gene3D G3DSA:1.10.3130.10 3 51 9.7E-20 T 28-03-2018 CDW54_RS05090 0cefa55223ac2f18ec4727c6bed0655a 178 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 117 150 8.4E-8 T 28-03-2018 IPR001451 Hexapeptide repeat CDW54_RS05090 0cefa55223ac2f18ec4727c6bed0655a 178 PIRSF PIRSF000441 2 178 3.0E-74 T 28-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 CDW54_RS07885 8d206ca27f611f0a9668b4e080636b49 62 Gene3D G3DSA:3.30.310.130 6 58 0.001 T 28-03-2018 CDW54_RS00995 6775086e322773b8c34a0b5c3851c67c 157 Gene3D G3DSA:1.10.10.10 12 101 4.4E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS00995 6775086e322773b8c34a0b5c3851c67c 157 Pfam PF01475 Ferric uptake regulator family 18 140 2.0E-35 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CDW54_RS00995 6775086e322773b8c34a0b5c3851c67c 157 SUPERFAMILY SSF46785 11 145 3.68E-37 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS01180 8663225a0a6a3b289329621f7d3f19f4 236 Gene3D G3DSA:3.40.225.10 6 236 1.4E-49 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CDW54_RS01180 8663225a0a6a3b289329621f7d3f19f4 236 SMART SM01007 12 203 3.1E-54 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CDW54_RS01180 8663225a0a6a3b289329621f7d3f19f4 236 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 13 201 5.4E-41 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CDW54_RS01180 8663225a0a6a3b289329621f7d3f19f4 236 SUPERFAMILY SSF53639 9 228 4.12E-66 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CDW54_RS03965 dd3debfcc49559e310c290a0f4124833 234 Gene3D G3DSA:3.30.460.10 1 146 4.3E-36 T 28-03-2018 CDW54_RS03965 dd3debfcc49559e310c290a0f4124833 234 Gene3D G3DSA:1.10.287.860 148 196 2.6E-21 T 28-03-2018 CDW54_RS03965 dd3debfcc49559e310c290a0f4124833 234 SUPERFAMILY SSF81301 1 198 5.01E-60 T 28-03-2018 CDW54_RS03965 dd3debfcc49559e310c290a0f4124833 234 SMART SM00954 44 165 1.1E-40 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 CDW54_RS03965 dd3debfcc49559e310c290a0f4124833 234 Pfam PF04607 Region found in RelA / SpoT proteins 44 162 1.8E-36 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 CDW54_RS04395 830bb2adc9334571729e0a8f621d1979 285 SUPERFAMILY SSF53067 2 282 8.3E-48 T 28-03-2018 CDW54_RS04395 830bb2adc9334571729e0a8f621d1979 285 ProSitePatterns PS01125 ROK family signature. 127 152 - T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CDW54_RS04395 830bb2adc9334571729e0a8f621d1979 285 Gene3D G3DSA:3.30.420.40 1 112 4.6E-18 T 28-03-2018 CDW54_RS04395 830bb2adc9334571729e0a8f621d1979 285 Pfam PF00480 ROK family 2 281 1.0E-74 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CDW54_RS04395 830bb2adc9334571729e0a8f621d1979 285 Gene3D G3DSA:3.30.420.40 113 285 4.9E-37 T 28-03-2018 CDW54_RS03405 3e948c1f561c48c9873831ce5b8c4f98 450 Gene3D G3DSA:3.40.1190.10 40 298 8.5E-40 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CDW54_RS03405 3e948c1f561c48c9873831ce5b8c4f98 450 Pfam PF08353 Domain of unknown function (DUF1727) 320 429 3.0E-34 T 28-03-2018 IPR013564 Domain of unknown function DUF1727 CDW54_RS03405 3e948c1f561c48c9873831ce5b8c4f98 450 Pfam PF08245 Mur ligase middle domain 54 282 1.6E-13 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CDW54_RS03405 3e948c1f561c48c9873831ce5b8c4f98 450 SUPERFAMILY SSF53623 239 296 3.77E-35 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CDW54_RS03405 3e948c1f561c48c9873831ce5b8c4f98 450 SUPERFAMILY SSF53623 40 193 3.77E-35 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CDW54_RS08095 5d401878cc115bb56c37cf7173f1bbef 112 SUPERFAMILY SSF50475 14 95 8.41E-12 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CDW54_RS08095 5d401878cc115bb56c37cf7173f1bbef 112 Gene3D G3DSA:2.30.110.10 4 111 1.3E-13 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CDW54_RS03845 0df9dfc7c8b3b75c282fb1fe51263c10 222 Pfam PF01842 ACT domain 152 213 4.0E-12 T 28-03-2018 IPR002912 ACT domain CDW54_RS03845 0df9dfc7c8b3b75c282fb1fe51263c10 222 Gene3D G3DSA:3.30.70.260 143 221 1.5E-17 T 28-03-2018 CDW54_RS03845 0df9dfc7c8b3b75c282fb1fe51263c10 222 Gene3D G3DSA:3.30.1330.90 16 83 6.2E-20 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CDW54_RS03845 0df9dfc7c8b3b75c282fb1fe51263c10 222 Gene3D G3DSA:3.30.1330.90 84 139 8.6E-5 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CDW54_RS03845 0df9dfc7c8b3b75c282fb1fe51263c10 222 TIGRFAM TIGR00719 sda_beta: L-serine dehydratase, iron-sulfur-dependent, beta subunit 5 204 2.0E-69 T 28-03-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CDW54_RS03845 0df9dfc7c8b3b75c282fb1fe51263c10 222 Pfam PF03315 Serine dehydratase beta chain 8 78 1.5E-12 T 28-03-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CDW54_RS03845 0df9dfc7c8b3b75c282fb1fe51263c10 222 SUPERFAMILY SSF143548 22 140 2.62E-30 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CDW54_RS03845 0df9dfc7c8b3b75c282fb1fe51263c10 222 SUPERFAMILY SSF55021 139 219 4.58E-20 T 28-03-2018 CDW54_RS03845 0df9dfc7c8b3b75c282fb1fe51263c10 222 PIRSF PIRSF036692 4 222 5.7E-102 T 28-03-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CDW54_RS06065 25f4cb9022765a4ef2c136efd2ce3bdb 289 SUPERFAMILY SSF52540 3 237 1.78E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS06065 25f4cb9022765a4ef2c136efd2ce3bdb 289 Gene3D G3DSA:3.40.50.300 1 260 2.0E-67 T 28-03-2018 CDW54_RS06065 25f4cb9022765a4ef2c136efd2ce3bdb 289 Pfam PF00005 ABC transporter 25 174 9.3E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS06065 25f4cb9022765a4ef2c136efd2ce3bdb 289 SMART SM00382 32 223 8.7E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS06065 25f4cb9022765a4ef2c136efd2ce3bdb 289 TIGRFAM TIGR04521 ECF_ATPase_2: energy-coupling factor transporter ATPase 3 279 2.1E-125 T 28-03-2018 IPR030946 Energy-coupling factor transporter ATP-binding protein EcfA2 CDW54_RS06065 25f4cb9022765a4ef2c136efd2ce3bdb 289 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS05330 0e6f1f56beab49eed65a908ddac2a27e 561 Gene3D G3DSA:3.20.20.80 57 486 8.3E-62 T 28-03-2018 CDW54_RS05330 0e6f1f56beab49eed65a908ddac2a27e 561 Pfam PF00128 Alpha amylase, catalytic domain 79 336 1.8E-24 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CDW54_RS05330 0e6f1f56beab49eed65a908ddac2a27e 561 SUPERFAMILY SSF51445 395 535 2.93E-93 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CDW54_RS05330 0e6f1f56beab49eed65a908ddac2a27e 561 SUPERFAMILY SSF51445 42 355 2.93E-93 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CDW54_RS05330 0e6f1f56beab49eed65a908ddac2a27e 561 PIRSF PIRSF003059 1 559 1.9E-203 T 28-03-2018 IPR016377 Sucrose phosphorylase-related GO:0005985|GO:0009018 KEGG: 00500+2.4.1.7|MetaCyc: PWY-5384 CDW54_RS05330 0e6f1f56beab49eed65a908ddac2a27e 561 SMART SM00642 61 463 8.9E-8 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CDW54_RS05330 0e6f1f56beab49eed65a908ddac2a27e 561 Gene3D G3DSA:2.60.40.1180 488 561 9.0E-10 T 28-03-2018 CDW54_RS09655 4084d29e5b4d325dd359125197091cec 300 Gene3D G3DSA:1.10.287.80 253 294 1.5E-12 T 28-03-2018 CDW54_RS09655 4084d29e5b4d325dd359125197091cec 300 Gene3D G3DSA:1.10.287.80 171 252 1.9E-18 T 28-03-2018 CDW54_RS09655 4084d29e5b4d325dd359125197091cec 300 Pfam PF00231 ATP synthase 4 299 8.9E-88 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS09655 4084d29e5b4d325dd359125197091cec 300 Gene3D G3DSA:1.10.287.80 6 170 1.4E-44 T 28-03-2018 CDW54_RS09655 4084d29e5b4d325dd359125197091cec 300 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 285 298 - T 28-03-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS09655 4084d29e5b4d325dd359125197091cec 300 Hamap MF_00815 ATP synthase gamma chain [atpG]. 2 299 32.653 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS09655 4084d29e5b4d325dd359125197091cec 300 SUPERFAMILY SSF52943 3 299 3.53E-83 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS09655 4084d29e5b4d325dd359125197091cec 300 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 3 299 6.1E-104 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS09655 4084d29e5b4d325dd359125197091cec 300 PRINTS PR00126 ATP synthase gamma subunit signature 277 298 3.5E-33 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS09655 4084d29e5b4d325dd359125197091cec 300 PRINTS PR00126 ATP synthase gamma subunit signature 178 195 3.5E-33 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS09655 4084d29e5b4d325dd359125197091cec 300 PRINTS PR00126 ATP synthase gamma subunit signature 85 104 3.5E-33 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS09655 4084d29e5b4d325dd359125197091cec 300 PRINTS PR00126 ATP synthase gamma subunit signature 246 265 3.5E-33 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDW54_RS01190 47090871d13ebb04088f0dd61b820486 212 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 4 202 5.7E-26 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CDW54_RS01190 47090871d13ebb04088f0dd61b820486 212 SMART SM00934 5 203 3.9E-35 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CDW54_RS01190 47090871d13ebb04088f0dd61b820486 212 SUPERFAMILY SSF51366 2 211 4.71E-40 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CDW54_RS01190 47090871d13ebb04088f0dd61b820486 212 Gene3D G3DSA:3.20.20.70 1 211 1.4E-25 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDW54_RS01600 017e49812b60be59492724f69eec2b41 359 Gene3D G3DSA:3.40.50.2000 24 159 2.2E-7 T 28-03-2018 CDW54_RS01600 017e49812b60be59492724f69eec2b41 359 Pfam PF00534 Glycosyl transferases group 1 162 314 1.5E-14 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CDW54_RS01600 017e49812b60be59492724f69eec2b41 359 Gene3D G3DSA:3.40.50.2000 160 326 1.5E-25 T 28-03-2018 CDW54_RS01600 017e49812b60be59492724f69eec2b41 359 SUPERFAMILY SSF53756 34 345 6.28E-49 T 28-03-2018 CDW54_RS01600 017e49812b60be59492724f69eec2b41 359 Pfam PF13439 Glycosyltransferase Family 4 51 151 2.0E-15 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CDW54_RS06440 c7bc04a3661e831a1d0f4e6247966aa8 530 Gene3D G3DSA:3.40.190.10 22 152 6.9E-30 T 28-03-2018 CDW54_RS06440 c7bc04a3661e831a1d0f4e6247966aa8 530 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 37 266 1.2E-37 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CDW54_RS06440 c7bc04a3661e831a1d0f4e6247966aa8 530 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 300 406 1.7E-18 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CDW54_RS06440 c7bc04a3661e831a1d0f4e6247966aa8 530 SMART SM00062 35 274 7.4E-36 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CDW54_RS06440 c7bc04a3661e831a1d0f4e6247966aa8 530 SUPERFAMILY SSF161098 299 500 8.76E-44 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS06440 c7bc04a3661e831a1d0f4e6247966aa8 530 SUPERFAMILY SSF53850 1 264 1.82E-47 T 28-03-2018 CDW54_RS06440 c7bc04a3661e831a1d0f4e6247966aa8 530 Gene3D G3DSA:3.40.190.10 153 223 1.3E-8 T 28-03-2018 CDW54_RS06440 c7bc04a3661e831a1d0f4e6247966aa8 530 Gene3D G3DSA:1.10.3720.10 293 513 6.0E-41 T 28-03-2018 CDW54_RS06440 c7bc04a3661e831a1d0f4e6247966aa8 530 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 341 511 4.0E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS01745 ba4657313f35b28ffb9fffdf3a297bbf 221 Gene3D G3DSA:3.40.50.720 2 137 1.6E-21 T 28-03-2018 CDW54_RS01745 ba4657313f35b28ffb9fffdf3a297bbf 221 SUPERFAMILY SSF116726 135 217 1.14E-18 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CDW54_RS01745 ba4657313f35b28ffb9fffdf3a297bbf 221 SUPERFAMILY SSF51735 4 134 2.29E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS01745 ba4657313f35b28ffb9fffdf3a297bbf 221 Pfam PF02080 TrkA-C domain 149 213 1.2E-11 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CDW54_RS01745 ba4657313f35b28ffb9fffdf3a297bbf 221 Pfam PF02254 TrkA-N domain 5 120 1.2E-30 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CDW54_RS01745 ba4657313f35b28ffb9fffdf3a297bbf 221 Gene3D G3DSA:3.30.70.1450 138 219 3.7E-17 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CDW54_RS07225 3ccc1e91cddb1357c088f11bad67dd8d 558 Gene3D G3DSA:3.90.226.10 3 272 1.9E-31 T 28-03-2018 CDW54_RS07225 3ccc1e91cddb1357c088f11bad67dd8d 558 Pfam PF01039 Carboxyl transferase domain 7 190 3.8E-14 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CDW54_RS07225 3ccc1e91cddb1357c088f11bad67dd8d 558 SUPERFAMILY SSF52096 343 509 1.19E-14 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CDW54_RS07225 3ccc1e91cddb1357c088f11bad67dd8d 558 TIGRFAM TIGR03134 malonate_gamma: biotin-independent malonate decarboxylase, gamma subunit 292 556 1.3E-93 T 28-03-2018 IPR009648 Biotin-dependent malonate decarboxylase, gamma subunit GO:0044262 MetaCyc: PWY-6060 CDW54_RS07225 3ccc1e91cddb1357c088f11bad67dd8d 558 TIGRFAM TIGR03133 malonate_beta: biotin-independent malonate decarboxylase, beta subunit 3 271 5.6E-107 T 28-03-2018 IPR017556 Biotin-independent malonate decarboxylase, beta subunit GO:0016831|GO:0044262 MetaCyc: PWY-6060 CDW54_RS07225 3ccc1e91cddb1357c088f11bad67dd8d 558 Gene3D G3DSA:3.90.226.10 362 555 1.3E-16 T 28-03-2018 CDW54_RS07225 3ccc1e91cddb1357c088f11bad67dd8d 558 SUPERFAMILY SSF52096 3 230 3.59E-29 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CDW54_RS07225 3ccc1e91cddb1357c088f11bad67dd8d 558 Pfam PF06833 Malonate decarboxylase gamma subunit (MdcE) 294 531 1.1E-55 T 28-03-2018 CDW54_RS03975 218e821eea7efbbb44ca7498be2ecd47 225 SUPERFAMILY SSF52833 3 165 1.32E-8 T 28-03-2018 IPR012336 Thioredoxin-like fold CDW54_RS03975 218e821eea7efbbb44ca7498be2ecd47 225 Gene3D G3DSA:3.40.30.10 1 185 8.4E-11 T 28-03-2018 CDW54_RS03975 218e821eea7efbbb44ca7498be2ecd47 225 Pfam PF13743 Thioredoxin 5 181 2.2E-60 T 28-03-2018 CDW54_RS07750 336d9ee5008e63020bb4757286fb2b35 337 ProSitePatterns PS00356 LacI-type HTH domain signature. 8 26 - T 28-03-2018 CDW54_RS07750 336d9ee5008e63020bb4757286fb2b35 337 SMART SM00354 5 76 1.2E-30 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS07750 336d9ee5008e63020bb4757286fb2b35 337 Pfam PF13377 Periplasmic binding protein-like domain 176 333 1.5E-33 T 28-03-2018 CDW54_RS07750 336d9ee5008e63020bb4757286fb2b35 337 Gene3D G3DSA:3.40.50.2300 59 178 7.6E-33 T 28-03-2018 CDW54_RS07750 336d9ee5008e63020bb4757286fb2b35 337 SUPERFAMILY SSF47413 4 64 1.33E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDW54_RS07750 336d9ee5008e63020bb4757286fb2b35 337 Gene3D G3DSA:1.10.260.40 6 58 1.3E-18 T 28-03-2018 CDW54_RS07750 336d9ee5008e63020bb4757286fb2b35 337 Gene3D G3DSA:3.40.50.2300 179 312 1.4E-39 T 28-03-2018 CDW54_RS07750 336d9ee5008e63020bb4757286fb2b35 337 SUPERFAMILY SSF53822 65 335 4.56E-78 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CDW54_RS07750 336d9ee5008e63020bb4757286fb2b35 337 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 53 4.5E-16 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS07455 7cf5d2fbba2278dffd9fb5143beac89f 434 Gene3D G3DSA:3.90.550.10 46 313 2.2E-52 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDW54_RS07455 7cf5d2fbba2278dffd9fb5143beac89f 434 SUPERFAMILY SSF53448 58 329 3.14E-51 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDW54_RS07455 7cf5d2fbba2278dffd9fb5143beac89f 434 Pfam PF00535 Glycosyl transferase family 2 64 235 1.1E-31 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CDW54_RS01185 8a96c33a20e855dfcc0658a7403fd887 286 TIGRFAM TIGR00542 hxl6Piso_put: putative hexulose-6-phosphate isomerase 3 283 3.0E-115 T 28-03-2018 IPR004560 L-ribulose-5-phosphate 3-epimerase GO:0005975|GO:0016861 KEGG: 00053+5.1.3.22|MetaCyc: PWY-6961 CDW54_RS01185 8a96c33a20e855dfcc0658a7403fd887 286 SUPERFAMILY SSF51658 12 278 3.01E-49 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CDW54_RS01185 8a96c33a20e855dfcc0658a7403fd887 286 Gene3D G3DSA:3.20.20.150 2 285 1.0E-52 T 28-03-2018 CDW54_RS01185 8a96c33a20e855dfcc0658a7403fd887 286 Pfam PF01261 Xylose isomerase-like TIM barrel 21 233 7.2E-36 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CDW54_RS01255 5c2812654406440f8d299eff4070d2e9 470 Pfam PF00367 phosphotransferase system, EIIB 397 428 1.7E-9 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CDW54_RS01255 5c2812654406440f8d299eff4070d2e9 470 Pfam PF02378 Phosphotransferase system, EIIC 12 301 1.7E-58 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CDW54_RS01255 5c2812654406440f8d299eff4070d2e9 470 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 407 424 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CDW54_RS01255 5c2812654406440f8d299eff4070d2e9 470 Gene3D G3DSA:3.30.1360.60 392 468 5.5E-22 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CDW54_RS01255 5c2812654406440f8d299eff4070d2e9 470 SUPERFAMILY SSF55604 394 468 1.96E-17 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CDW54_RS07305 6e32dc95dd2ed7935541f40a6988c5f7 236 Pfam PF03483 B3/4 domain 68 208 3.2E-23 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CDW54_RS07305 6e32dc95dd2ed7935541f40a6988c5f7 236 SMART SM00873 66 212 1.0E-8 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CDW54_RS07305 6e32dc95dd2ed7935541f40a6988c5f7 236 SUPERFAMILY SSF56037 52 228 7.06E-34 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CDW54_RS07305 6e32dc95dd2ed7935541f40a6988c5f7 236 Gene3D G3DSA:3.50.40.10 60 218 2.9E-25 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CDW54_RS06225 c7486d77c3d9f2a5c22f3ec0c31e716f 316 Gene3D G3DSA:1.10.3470.10 2 316 6.1E-44 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CDW54_RS06225 c7486d77c3d9f2a5c22f3ec0c31e716f 316 SUPERFAMILY SSF81345 5 311 4.71E-67 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CDW54_RS06225 c7486d77c3d9f2a5c22f3ec0c31e716f 316 Pfam PF01032 FecCD transport family 9 311 9.3E-65 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CDW54_RS03820 30830afa3c3c73a9171da570c0a63e46 229 Pfam PF09335 SNARE associated Golgi protein 74 187 4.8E-14 T 28-03-2018 IPR032816 SNARE associated Golgi protein CDW54_RS10705 2e6cb511304548765b9b5d0d126d5099 232 SUPERFAMILY SSF144091 12 194 1.57E-40 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CDW54_RS10705 2e6cb511304548765b9b5d0d126d5099 232 Gene3D G3DSA:1.20.1540.10 13 193 1.6E-38 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CDW54_RS10705 2e6cb511304548765b9b5d0d126d5099 232 Pfam PF01694 Rhomboid family 55 193 2.0E-33 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CDW54_RS07205 55c1b5be480f9be5b4f4cc2feda6b6bb 285 Pfam PF03466 LysR substrate binding domain 99 261 9.3E-24 T 28-03-2018 IPR005119 LysR, substrate-binding CDW54_RS07205 55c1b5be480f9be5b4f4cc2feda6b6bb 285 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 61 2.2E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDW54_RS07205 55c1b5be480f9be5b4f4cc2feda6b6bb 285 Gene3D G3DSA:1.10.10.10 1 82 1.2E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS07205 55c1b5be480f9be5b4f4cc2feda6b6bb 285 SUPERFAMILY SSF46785 1 87 2.18E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS07205 55c1b5be480f9be5b4f4cc2feda6b6bb 285 SUPERFAMILY SSF53850 100 280 4.81E-23 T 28-03-2018 CDW54_RS07205 55c1b5be480f9be5b4f4cc2feda6b6bb 285 Gene3D G3DSA:3.40.190.10 93 166 1.3E-8 T 28-03-2018 CDW54_RS07205 55c1b5be480f9be5b4f4cc2feda6b6bb 285 Gene3D G3DSA:3.40.190.10 167 253 3.8E-18 T 28-03-2018 CDW54_RS07205 55c1b5be480f9be5b4f4cc2feda6b6bb 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.5E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDW54_RS07205 55c1b5be480f9be5b4f4cc2feda6b6bb 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.5E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDW54_RS07205 55c1b5be480f9be5b4f4cc2feda6b6bb 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.5E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDW54_RS09425 c09cbb134223f1393b21909252315f5c 239 Pfam PF07722 Peptidase C26 3 219 8.5E-65 T 28-03-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 CDW54_RS09425 c09cbb134223f1393b21909252315f5c 239 SUPERFAMILY SSF52317 24 237 5.66E-36 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CDW54_RS09425 c09cbb134223f1393b21909252315f5c 239 Gene3D G3DSA:3.40.50.880 1 239 7.8E-44 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CDW54_RS10720 ee88400c33644b2fc572fcfa351196d2 131 Gene3D G3DSA:3.40.250.10 21 128 1.0E-23 T 28-03-2018 IPR001763 Rhodanese-like domain CDW54_RS10720 ee88400c33644b2fc572fcfa351196d2 131 Pfam PF00581 Rhodanese-like domain 38 124 6.9E-16 T 28-03-2018 IPR001763 Rhodanese-like domain CDW54_RS10720 ee88400c33644b2fc572fcfa351196d2 131 SUPERFAMILY SSF52821 12 124 4.58E-28 T 28-03-2018 IPR001763 Rhodanese-like domain CDW54_RS10720 ee88400c33644b2fc572fcfa351196d2 131 SMART SM00450 33 128 1.3E-22 T 28-03-2018 IPR001763 Rhodanese-like domain CDW54_RS09390 0d8642a1e7580a6be455a0b177b3ae4f 104 PRINTS PR00421 Thioredoxin family signature 68 79 3.3E-7 T 28-03-2018 CDW54_RS09390 0d8642a1e7580a6be455a0b177b3ae4f 104 PRINTS PR00421 Thioredoxin family signature 27 36 3.3E-7 T 28-03-2018 CDW54_RS09390 0d8642a1e7580a6be455a0b177b3ae4f 104 PRINTS PR00421 Thioredoxin family signature 19 27 3.3E-7 T 28-03-2018 CDW54_RS09390 0d8642a1e7580a6be455a0b177b3ae4f 104 PIRSF PIRSF000077 1 104 1.0E-39 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CDW54_RS09390 0d8642a1e7580a6be455a0b177b3ae4f 104 Pfam PF00085 Thioredoxin 4 102 3.5E-30 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 CDW54_RS09390 0d8642a1e7580a6be455a0b177b3ae4f 104 SUPERFAMILY SSF52833 3 104 3.36E-37 T 28-03-2018 IPR012336 Thioredoxin-like fold CDW54_RS09390 0d8642a1e7580a6be455a0b177b3ae4f 104 Gene3D G3DSA:3.40.30.10 1 104 6.4E-34 T 28-03-2018 CDW54_RS09390 0d8642a1e7580a6be455a0b177b3ae4f 104 TIGRFAM TIGR01068 thioredoxin: thioredoxin 6 103 9.4E-36 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CDW54_RS09390 0d8642a1e7580a6be455a0b177b3ae4f 104 ProSitePatterns PS00194 Thioredoxin family active site. 20 38 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CDW54_RS05600 561fd042167e26b7664ee1dc97814f47 119 Pfam PF13240 zinc-ribbon domain 2 22 1.4E-6 T 28-03-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 CDW54_RS04430 157dea240dbabe6b0e68e432da82a5de 574 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 472 573 1.1E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS04430 157dea240dbabe6b0e68e432da82a5de 574 Gene3D G3DSA:3.30.565.10 331 571 2.1E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS04430 157dea240dbabe6b0e68e432da82a5de 574 SUPERFAMILY SSF158472 314 358 6.8E-5 T 28-03-2018 CDW54_RS04430 157dea240dbabe6b0e68e432da82a5de 574 SMART SM00304 307 360 6.5E-5 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDW54_RS04430 157dea240dbabe6b0e68e432da82a5de 574 SUPERFAMILY SSF55874 428 571 3.01E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS04430 157dea240dbabe6b0e68e432da82a5de 574 Pfam PF06580 Histidine kinase 373 449 3.0E-24 T 28-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 CDW54_RS08295 eecba063f00cb190c4b06b023c6aac1c 281 Gene3D G3DSA:1.10.10.10 1 83 6.1E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS08295 eecba063f00cb190c4b06b023c6aac1c 281 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 60 1.5E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDW54_RS08295 eecba063f00cb190c4b06b023c6aac1c 281 SUPERFAMILY SSF53850 86 264 3.98E-22 T 28-03-2018 CDW54_RS08295 eecba063f00cb190c4b06b023c6aac1c 281 Gene3D G3DSA:3.40.190.10 85 212 1.4E-16 T 28-03-2018 CDW54_RS08295 eecba063f00cb190c4b06b023c6aac1c 281 Pfam PF03466 LysR substrate binding domain 87 230 1.3E-19 T 28-03-2018 IPR005119 LysR, substrate-binding CDW54_RS08295 eecba063f00cb190c4b06b023c6aac1c 281 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 49 2.0E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDW54_RS08295 eecba063f00cb190c4b06b023c6aac1c 281 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 28 38 2.0E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDW54_RS08295 eecba063f00cb190c4b06b023c6aac1c 281 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 17 28 2.0E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDW54_RS08295 eecba063f00cb190c4b06b023c6aac1c 281 SUPERFAMILY SSF46785 3 110 8.65E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS06630 be2d235b3d4c7c7acbbb2c49085c4b7e 87 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 5 69 5.0E-11 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CDW54_RS06630 be2d235b3d4c7c7acbbb2c49085c4b7e 87 Gene3D G3DSA:3.40.1620.10 4 43 5.0E-13 T 28-03-2018 CDW54_RS06630 be2d235b3d4c7c7acbbb2c49085c4b7e 87 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 9 57 1.2E-9 T 28-03-2018 CDW54_RS06630 be2d235b3d4c7c7acbbb2c49085c4b7e 87 SUPERFAMILY SSF143120 5 59 2.09E-11 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CDW54_RS12490 702d239cd5d0f799b3e9970d0d8b3c42 396 Gene3D G3DSA:3.40.640.10 53 287 1.3E-56 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDW54_RS12490 702d239cd5d0f799b3e9970d0d8b3c42 396 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 241 250 - T 28-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CDW54_RS12490 702d239cd5d0f799b3e9970d0d8b3c42 396 TIGRFAM TIGR01825 gly_Cac_T_rel: putative pyridoxal phosphate-dependent acyltransferase 10 396 6.5E-187 T 28-03-2018 IPR010962 Putative 8-amino-7-oxononanoate synthase, Archaea/Firmicutes type CDW54_RS12490 702d239cd5d0f799b3e9970d0d8b3c42 396 SUPERFAMILY SSF53383 8 394 2.06E-113 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDW54_RS12490 702d239cd5d0f799b3e9970d0d8b3c42 396 Gene3D G3DSA:3.90.1150.10 288 396 1.8E-29 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDW54_RS12490 702d239cd5d0f799b3e9970d0d8b3c42 396 Pfam PF00155 Aminotransferase class I and II 42 384 1.5E-69 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CDW54_RS02600 b4deb632476721e26d0fa1726d95e0c1 279 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 271 1.1E-56 T 28-03-2018 IPR000150 Cof family GO:0016787 CDW54_RS02600 b4deb632476721e26d0fa1726d95e0c1 279 Gene3D G3DSA:3.40.50.1000 1 277 1.6E-42 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS02600 b4deb632476721e26d0fa1726d95e0c1 279 SUPERFAMILY SSF56784 1 276 3.95E-63 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS02600 b4deb632476721e26d0fa1726d95e0c1 279 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 270 1.0E-60 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS02600 b4deb632476721e26d0fa1726d95e0c1 279 ProSitePatterns PS01228 Hypothetical cof family signature 1. 4 15 - T 28-03-2018 CDW54_RS02600 b4deb632476721e26d0fa1726d95e0c1 279 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 245 9.4E-24 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CDW54_RS07985 a91e8415e7c9ee283e3b6fa307ed5977 301 SUPERFAMILY SSF46689 224 275 3.9E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDW54_RS07985 a91e8415e7c9ee283e3b6fa307ed5977 301 Gene3D G3DSA:1.10.10.60 225 286 5.4E-11 T 28-03-2018 CDW54_RS07985 a91e8415e7c9ee283e3b6fa307ed5977 301 Gene3D G3DSA:2.60.120.280 7 161 6.8E-18 T 28-03-2018 CDW54_RS07985 a91e8415e7c9ee283e3b6fa307ed5977 301 Pfam PF12833 Helix-turn-helix domain 194 273 3.6E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CDW54_RS07985 a91e8415e7c9ee283e3b6fa307ed5977 301 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 225 267 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CDW54_RS07985 a91e8415e7c9ee283e3b6fa307ed5977 301 SMART SM00342 188 271 2.6E-27 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CDW54_RS07985 a91e8415e7c9ee283e3b6fa307ed5977 301 Gene3D G3DSA:1.10.10.60 166 224 9.8E-15 T 28-03-2018 CDW54_RS07985 a91e8415e7c9ee283e3b6fa307ed5977 301 SUPERFAMILY SSF46689 176 221 8.87E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDW54_RS07985 a91e8415e7c9ee283e3b6fa307ed5977 301 Pfam PF02311 AraC-like ligand binding domain 20 152 7.2E-24 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CDW54_RS07985 a91e8415e7c9ee283e3b6fa307ed5977 301 SUPERFAMILY SSF51215 6 157 2.35E-29 T 28-03-2018 CDW54_RS08585 b58fe27b7c465d0b3294005c9d9b0f29 299 Gene3D G3DSA:2.70.98.10 1 298 7.6E-51 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CDW54_RS08585 b58fe27b7c465d0b3294005c9d9b0f29 299 Pfam PF01263 Aldose 1-epimerase 2 275 2.8E-39 T 28-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 CDW54_RS08585 b58fe27b7c465d0b3294005c9d9b0f29 299 SUPERFAMILY SSF74650 2 297 7.53E-46 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CDW54_RS00440 78f483058a85cb6f576d562d5aee4320 162 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 5 161 9.0E-67 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CDW54_RS00440 78f483058a85cb6f576d562d5aee4320 162 PIRSF PIRSF001338 1 162 2.7E-70 T 28-03-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 CDW54_RS00440 78f483058a85cb6f576d562d5aee4320 162 Gene3D G3DSA:3.40.50.7700 1 162 8.9E-68 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CDW54_RS00440 78f483058a85cb6f576d562d5aee4320 162 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 5 158 33.634 T 28-03-2018 IPR033747 Class I PurE CDW54_RS00440 78f483058a85cb6f576d562d5aee4320 162 Pfam PF00731 AIR carboxylase 4 150 2.4E-65 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CDW54_RS00440 78f483058a85cb6f576d562d5aee4320 162 SMART SM01001 3 154 3.2E-105 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CDW54_RS00440 78f483058a85cb6f576d562d5aee4320 162 SUPERFAMILY SSF52255 4 160 6.67E-68 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CDW54_RS04185 f0e5b77016b06e79b86e0aa4d8fd59f2 584 SUPERFAMILY SSF51338 317 354 4.0E-16 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CDW54_RS04185 f0e5b77016b06e79b86e0aa4d8fd59f2 584 SUPERFAMILY SSF51338 10 69 4.0E-16 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CDW54_RS04185 f0e5b77016b06e79b86e0aa4d8fd59f2 584 Gene3D G3DSA:3.20.20.140 74 239 2.5E-13 T 28-03-2018 CDW54_RS04185 f0e5b77016b06e79b86e0aa4d8fd59f2 584 Pfam PF01979 Amidohydrolase family 65 342 1.1E-32 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CDW54_RS04185 f0e5b77016b06e79b86e0aa4d8fd59f2 584 SUPERFAMILY SSF51556 69 317 2.92E-45 T 28-03-2018 IPR032466 Metal-dependent hydrolase CDW54_RS04185 f0e5b77016b06e79b86e0aa4d8fd59f2 584 Gene3D G3DSA:2.30.40.10 255 357 2.9E-16 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CDW54_RS04185 f0e5b77016b06e79b86e0aa4d8fd59f2 584 Gene3D G3DSA:2.30.40.10 15 73 6.5E-15 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CDW54_RS04185 f0e5b77016b06e79b86e0aa4d8fd59f2 584 Pfam PF13382 Adenine deaminase C-terminal domain 402 570 6.9E-64 T 28-03-2018 IPR026912 Adenine deaminase C-terminal domain KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 CDW54_RS04185 f0e5b77016b06e79b86e0aa4d8fd59f2 584 Hamap MF_01518 Adenine deaminase [ade]. 19 573 38.641 T 28-03-2018 IPR006679 Adenine deaminase GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 CDW54_RS04185 f0e5b77016b06e79b86e0aa4d8fd59f2 584 TIGRFAM TIGR01178 ade: adenine deaminase 19 572 1.6E-196 T 28-03-2018 IPR006679 Adenine deaminase GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 CDW54_RS03220 84d6bc6dc6c3813c23e4ae1e16a4e902 313 SUPERFAMILY SSF161098 94 294 3.43E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS03220 84d6bc6dc6c3813c23e4ae1e16a4e902 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 306 4.6E-41 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS03220 84d6bc6dc6c3813c23e4ae1e16a4e902 313 Gene3D G3DSA:1.10.3720.10 2 295 2.4E-38 T 28-03-2018 CDW54_RS01380 d032291606edb0ae25d15c43fd1404b6 228 SUPERFAMILY SSF46894 128 226 7.29E-30 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDW54_RS01380 d032291606edb0ae25d15c43fd1404b6 228 Pfam PF00072 Response regulator receiver domain 4 112 1.2E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDW54_RS01380 d032291606edb0ae25d15c43fd1404b6 228 SMART SM00862 151 226 1.1E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDW54_RS01380 d032291606edb0ae25d15c43fd1404b6 228 SMART SM00448 2 112 2.0E-40 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDW54_RS01380 d032291606edb0ae25d15c43fd1404b6 228 Gene3D G3DSA:1.10.10.10 130 228 1.2E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS01380 d032291606edb0ae25d15c43fd1404b6 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 226 1.1E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDW54_RS01380 d032291606edb0ae25d15c43fd1404b6 228 SUPERFAMILY SSF52172 2 123 2.42E-39 T 28-03-2018 IPR011006 CheY-like superfamily CDW54_RS01380 d032291606edb0ae25d15c43fd1404b6 228 Gene3D G3DSA:3.40.50.2300 1 129 1.0E-32 T 28-03-2018 CDW54_RS08965 0748a75e1d69e91c43b7f9c9efad6855 301 Pfam PF00005 ABC transporter 19 157 1.5E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS08965 0748a75e1d69e91c43b7f9c9efad6855 301 SUPERFAMILY SSF52540 4 222 1.59E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS08965 0748a75e1d69e91c43b7f9c9efad6855 301 Gene3D G3DSA:3.40.50.300 2 283 1.3E-55 T 28-03-2018 CDW54_RS08965 0748a75e1d69e91c43b7f9c9efad6855 301 SMART SM00382 28 205 1.4E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS08965 0748a75e1d69e91c43b7f9c9efad6855 301 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS08755 d03a9166b7743614b10839ce46214a91 108 Pfam PF12643 MazG-like family 27 108 5.5E-26 T 28-03-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 CDW54_RS08755 d03a9166b7743614b10839ce46214a91 108 SUPERFAMILY SSF101386 5 107 1.18E-35 T 28-03-2018 CDW54_RS08755 d03a9166b7743614b10839ce46214a91 108 Gene3D G3DSA:1.10.4010.10 1 106 5.3E-21 T 28-03-2018 CDW54_RS08755 d03a9166b7743614b10839ce46214a91 108 PIRSF PIRSF029826 2 108 1.0E-38 T 28-03-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 CDW54_RS00935 0ab6832e9cda5a680911de150eeca0b5 467 Pfam PF00270 DEAD/DEAH box helicase 17 174 7.2E-20 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CDW54_RS00935 0ab6832e9cda5a680911de150eeca0b5 467 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 6 333 8.1E-107 T 28-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 CDW54_RS00935 0ab6832e9cda5a680911de150eeca0b5 467 Gene3D G3DSA:1.10.10.10 340 437 8.1E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS00935 0ab6832e9cda5a680911de150eeca0b5 467 Gene3D G3DSA:3.40.50.300 197 339 8.4E-34 T 28-03-2018 CDW54_RS00935 0ab6832e9cda5a680911de150eeca0b5 467 Gene3D G3DSA:3.40.50.300 1 196 3.7E-35 T 28-03-2018 CDW54_RS00935 0ab6832e9cda5a680911de150eeca0b5 467 Pfam PF00271 Helicase conserved C-terminal domain 218 315 1.5E-22 T 28-03-2018 IPR001650 Helicase, C-terminal CDW54_RS00935 0ab6832e9cda5a680911de150eeca0b5 467 SUPERFAMILY SSF52540 55 337 1.16E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS00935 0ab6832e9cda5a680911de150eeca0b5 467 SMART SM00490 237 317 2.5E-28 T 28-03-2018 IPR001650 Helicase, C-terminal CDW54_RS00935 0ab6832e9cda5a680911de150eeca0b5 467 SMART SM00487 11 202 1.3E-27 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CDW54_RS00935 0ab6832e9cda5a680911de150eeca0b5 467 Pfam PF16124 RecQ zinc-binding 385 430 1.3E-9 T 28-03-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain CDW54_RS08110 4d40c84590383f97e505bb14a7ab2688 113 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 10 113 9.3E-24 T 28-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 CDW54_RS08110 4d40c84590383f97e505bb14a7ab2688 113 Gene3D G3DSA:2.30.30.110 4 113 1.1E-27 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CDW54_RS08110 4d40c84590383f97e505bb14a7ab2688 113 SUPERFAMILY SSF50118 7 113 1.24E-29 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CDW54_RS07555 fe3c4b1bbd6ec9d36bcbdb5024dcfecc 764 PIRSF PIRSF036289 1 761 7.4E-279 T 28-03-2018 IPR017045 Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase CDW54_RS07555 fe3c4b1bbd6ec9d36bcbdb5024dcfecc 764 Gene3D G3DSA:1.50.10.10 318 680 9.1E-120 T 28-03-2018 CDW54_RS07555 fe3c4b1bbd6ec9d36bcbdb5024dcfecc 764 Gene3D G3DSA:2.60.420.10 681 752 4.9E-21 T 28-03-2018 CDW54_RS07555 fe3c4b1bbd6ec9d36bcbdb5024dcfecc 764 SUPERFAMILY SSF74650 5 270 2.26E-88 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CDW54_RS07555 fe3c4b1bbd6ec9d36bcbdb5024dcfecc 764 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 324 695 1.7E-154 T 28-03-2018 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 CDW54_RS07555 fe3c4b1bbd6ec9d36bcbdb5024dcfecc 764 Gene3D G3DSA:2.70.98.40 4 272 1.2E-67 T 28-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 CDW54_RS07555 fe3c4b1bbd6ec9d36bcbdb5024dcfecc 764 SUPERFAMILY SSF48208 276 747 3.67E-139 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CDW54_RS07555 fe3c4b1bbd6ec9d36bcbdb5024dcfecc 764 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 17 269 7.3E-58 T 28-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 CDW54_RS07555 fe3c4b1bbd6ec9d36bcbdb5024dcfecc 764 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 699 749 1.1E-17 T 28-03-2018 IPR005194 Glycoside hydrolase family 65, C-terminal CDW54_RS00505 a0dd35ac6cc961f9d087fc68d7aa5012 318 SUPERFAMILY SSF51735 3 153 3.48E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS00505 a0dd35ac6cc961f9d087fc68d7aa5012 318 Gene3D G3DSA:3.40.50.720 1 144 7.0E-39 T 28-03-2018 CDW54_RS00505 a0dd35ac6cc961f9d087fc68d7aa5012 318 Gene3D G3DSA:3.30.360.10 145 315 2.2E-23 T 28-03-2018 CDW54_RS00505 a0dd35ac6cc961f9d087fc68d7aa5012 318 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 119 8.6E-26 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CDW54_RS00505 a0dd35ac6cc961f9d087fc68d7aa5012 318 SUPERFAMILY SSF55347 127 290 2.45E-35 T 28-03-2018 CDW54_RS04015 9a934abc58ec53ae31fd7723ddcd088c 373 SUPERFAMILY SSF56300 1 314 4.1E-53 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CDW54_RS04015 9a934abc58ec53ae31fd7723ddcd088c 373 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 241 9.0E-50 T 28-03-2018 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 CDW54_RS04015 9a934abc58ec53ae31fd7723ddcd088c 373 Gene3D G3DSA:3.60.21.10 71 262 5.4E-26 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CDW54_RS04015 9a934abc58ec53ae31fd7723ddcd088c 373 Gene3D G3DSA:3.60.21.10 1 70 2.1E-14 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CDW54_RS04015 9a934abc58ec53ae31fd7723ddcd088c 373 Pfam PF00149 Calcineurin-like phosphoesterase 1 212 3.8E-15 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CDW54_RS04015 9a934abc58ec53ae31fd7723ddcd088c 373 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 260 349 1.1E-12 T 28-03-2018 IPR026843 Nuclease SbcCD subunit D, C-terminal domain CDW54_RS00405 cac382c149cd76cfd48ff0a56d96b483 740 Pfam PF02769 AIR synthase related protein, C-terminal domain 208 362 6.2E-34 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CDW54_RS00405 cac382c149cd76cfd48ff0a56d96b483 740 Pfam PF02769 AIR synthase related protein, C-terminal domain 580 709 6.6E-12 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CDW54_RS00405 cac382c149cd76cfd48ff0a56d96b483 740 Gene3D G3DSA:3.30.1330.10 422 570 1.8E-49 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CDW54_RS00405 cac382c149cd76cfd48ff0a56d96b483 740 Pfam PF00586 AIR synthase related protein, N-terminal domain 448 565 3.0E-23 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CDW54_RS00405 cac382c149cd76cfd48ff0a56d96b483 740 Pfam PF00586 AIR synthase related protein, N-terminal domain 93 195 4.1E-25 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CDW54_RS00405 cac382c149cd76cfd48ff0a56d96b483 740 Gene3D G3DSA:3.90.650.10 572 740 2.6E-28 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CDW54_RS00405 cac382c149cd76cfd48ff0a56d96b483 740 Gene3D G3DSA:3.90.650.10 201 381 3.7E-28 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CDW54_RS00405 cac382c149cd76cfd48ff0a56d96b483 740 SUPERFAMILY SSF55326 406 572 5.63E-55 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CDW54_RS00405 cac382c149cd76cfd48ff0a56d96b483 740 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 740 317.206 T 28-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CDW54_RS00405 cac382c149cd76cfd48ff0a56d96b483 740 SUPERFAMILY SSF55326 18 203 1.94E-52 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CDW54_RS00405 cac382c149cd76cfd48ff0a56d96b483 740 SUPERFAMILY SSF56042 205 433 4.78E-54 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CDW54_RS00405 cac382c149cd76cfd48ff0a56d96b483 740 SUPERFAMILY SSF56042 574 739 6.88E-35 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CDW54_RS00405 cac382c149cd76cfd48ff0a56d96b483 740 PIRSF PIRSF001587 5 740 0.0 T 28-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CDW54_RS00405 cac382c149cd76cfd48ff0a56d96b483 740 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 23 738 8.8E-295 T 28-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CDW54_RS00405 cac382c149cd76cfd48ff0a56d96b483 740 Gene3D G3DSA:3.30.1330.10 23 200 3.8E-57 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CDW54_RS02995 f86a6bf054ea2acb5b9f52165ab8c94b 112 Gene3D G3DSA:2.30.30.40 44 111 4.5E-36 T 28-03-2018 CDW54_RS02995 f86a6bf054ea2acb5b9f52165ab8c94b 112 SUPERFAMILY SSF82057 40 111 5.04E-28 T 28-03-2018 CDW54_RS02995 f86a6bf054ea2acb5b9f52165ab8c94b 112 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 3 112 7.5E-50 T 28-03-2018 IPR004624 PhnA protein CDW54_RS02995 f86a6bf054ea2acb5b9f52165ab8c94b 112 SUPERFAMILY SSF57783 1 36 3.23E-14 T 28-03-2018 CDW54_RS02995 f86a6bf054ea2acb5b9f52165ab8c94b 112 Gene3D G3DSA:2.20.25.10 1 38 1.1E-16 T 28-03-2018 CDW54_RS02995 f86a6bf054ea2acb5b9f52165ab8c94b 112 Pfam PF08274 PhnA Zinc-Ribbon 2 30 1.0E-15 T 28-03-2018 IPR013987 PhnA protein, N-terminal CDW54_RS02995 f86a6bf054ea2acb5b9f52165ab8c94b 112 Pfam PF03831 PhnA domain 45 112 1.0E-33 T 28-03-2018 IPR013988 PhnA protein, C-terminal CDW54_RS06250 8c18c65efd95feae225b82f66cbfde0b 118 SUPERFAMILY SSF89360 1 116 4.71E-26 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CDW54_RS06250 8c18c65efd95feae225b82f66cbfde0b 118 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 115 9.0E-22 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CDW54_RS06250 8c18c65efd95feae225b82f66cbfde0b 118 Gene3D G3DSA:2.60.300.12 1 118 9.5E-27 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CDW54_RS07800 e97598969c1bb13cefd24413be8189ad 200 Pfam PF04647 Accessory gene regulator B 4 179 3.4E-28 T 28-03-2018 IPR006741 Accessory gene regulator B GO:0008233|GO:0009372|GO:0009405|GO:0016021 CDW54_RS07800 e97598969c1bb13cefd24413be8189ad 200 SMART SM00793 4 189 3.0E-31 T 28-03-2018 IPR006741 Accessory gene regulator B GO:0008233|GO:0009372|GO:0009405|GO:0016021 CDW54_RS03360 eb8e7f6dc67918eefe8ff3a613c78894 357 Gene3D G3DSA:1.20.58.410 1 99 3.8E-16 T 28-03-2018 CDW54_RS03360 eb8e7f6dc67918eefe8ff3a613c78894 357 SUPERFAMILY SSF75620 8 351 7.19E-134 T 28-03-2018 CDW54_RS03360 eb8e7f6dc67918eefe8ff3a613c78894 357 Gene3D G3DSA:3.30.160.20 207 290 1.9E-31 T 28-03-2018 CDW54_RS03360 eb8e7f6dc67918eefe8ff3a613c78894 357 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 3 355 3.7E-166 T 28-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 CDW54_RS03360 eb8e7f6dc67918eefe8ff3a613c78894 357 Pfam PF00472 RF-1 domain 210 319 8.2E-41 T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CDW54_RS03360 eb8e7f6dc67918eefe8ff3a613c78894 357 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 1 355 40.742 T 28-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 CDW54_RS03360 eb8e7f6dc67918eefe8ff3a613c78894 357 Pfam PF03462 PCRF domain 8 202 1.9E-73 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 CDW54_RS03360 eb8e7f6dc67918eefe8ff3a613c78894 357 SMART SM00937 63 177 1.4E-63 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 CDW54_RS03360 eb8e7f6dc67918eefe8ff3a613c78894 357 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 226 242 - T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CDW54_RS03560 e41df038c1549825f7d54eb7b184e90d 319 SUPERFAMILY SSF75005 6 316 6.64E-65 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CDW54_RS03560 e41df038c1549825f7d54eb7b184e90d 319 PIRSF PIRSF025414 1 319 3.8E-148 T 28-03-2018 IPR016828 Alpha-L-arabinofuranosidase KEGG: 00520+3.2.1.55 CDW54_RS03560 e41df038c1549825f7d54eb7b184e90d 319 Pfam PF04616 Glycosyl hydrolases family 43 6 309 1.9E-63 T 28-03-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 CDW54_RS03560 e41df038c1549825f7d54eb7b184e90d 319 Gene3D G3DSA:2.115.10.20 2 316 2.5E-58 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CDW54_RS08230 d12b924e34ad4298b8df65d542be15f1 199 Pfam PF00149 Calcineurin-like phosphoesterase 4 173 2.2E-7 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CDW54_RS08230 d12b924e34ad4298b8df65d542be15f1 199 SUPERFAMILY SSF56300 4 161 4.86E-17 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CDW54_RS08230 d12b924e34ad4298b8df65d542be15f1 199 Gene3D G3DSA:3.60.21.10 3 197 3.5E-18 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CDW54_RS10600 9865826794f319b8d13b9de3bd4ba186 319 Gene3D G3DSA:3.30.420.10 155 317 4.9E-22 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS10600 9865826794f319b8d13b9de3bd4ba186 319 Pfam PF00665 Integrase core domain 170 265 7.8E-10 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CDW54_RS10600 9865826794f319b8d13b9de3bd4ba186 319 SUPERFAMILY SSF53098 160 309 3.04E-21 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS10600 9865826794f319b8d13b9de3bd4ba186 319 Gene3D G3DSA:1.10.10.60 6 68 1.1E-4 T 28-03-2018 CDW54_RS11525 5dcd0addb0a5b7fa93d316d9e158e109 406 Pfam PF13530 Sterol carrier protein domain 191 402 2.3E-57 T 28-03-2018 IPR025559 Enhanced intracellular survival protein domain CDW54_RS11525 5dcd0addb0a5b7fa93d316d9e158e109 406 Gene3D G3DSA:3.40.630.30 149 293 8.5E-41 T 28-03-2018 CDW54_RS11525 5dcd0addb0a5b7fa93d316d9e158e109 406 Gene3D G3DSA:3.30.1050.10 294 400 1.7E-25 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CDW54_RS11525 5dcd0addb0a5b7fa93d316d9e158e109 406 SUPERFAMILY SSF55718 301 406 7.06E-31 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CDW54_RS11525 5dcd0addb0a5b7fa93d316d9e158e109 406 SUPERFAMILY SSF55729 10 300 4.43E-81 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDW54_RS11525 5dcd0addb0a5b7fa93d316d9e158e109 406 Gene3D G3DSA:3.40.630.30 1 148 8.4E-12 T 28-03-2018 CDW54_RS11525 5dcd0addb0a5b7fa93d316d9e158e109 406 Pfam PF13527 Acetyltransferase (GNAT) domain 12 145 4.3E-41 T 28-03-2018 CDW54_RS01845 cb373c98f80720ac3e376afb6650d0e5 406 Pfam PF00005 ABC transporter 43 175 1.7E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS01845 cb373c98f80720ac3e376afb6650d0e5 406 Pfam PF14524 Wzt C-terminal domain 267 367 1.1E-15 T 28-03-2018 IPR029439 Wzt, C-terminal CDW54_RS01845 cb373c98f80720ac3e376afb6650d0e5 406 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS01845 cb373c98f80720ac3e376afb6650d0e5 406 Gene3D G3DSA:3.40.50.300 2 257 1.3E-50 T 28-03-2018 CDW54_RS01845 cb373c98f80720ac3e376afb6650d0e5 406 Gene3D G3DSA:2.70.50.60 258 391 7.1E-24 T 28-03-2018 CDW54_RS01845 cb373c98f80720ac3e376afb6650d0e5 406 SUPERFAMILY SSF52540 30 254 1.66E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS01845 cb373c98f80720ac3e376afb6650d0e5 406 SMART SM00382 52 223 3.0E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS08075 feb449320878a779c22088ded7643cf5 442 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 332 438 2.7E-24 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CDW54_RS08075 feb449320878a779c22088ded7643cf5 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 160 185 1.6E-49 T 28-03-2018 CDW54_RS08075 feb449320878a779c22088ded7643cf5 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 328 349 1.6E-49 T 28-03-2018 CDW54_RS08075 feb449320878a779c22088ded7643cf5 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 415 435 1.6E-49 T 28-03-2018 CDW54_RS08075 feb449320878a779c22088ded7643cf5 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 291 298 1.6E-49 T 28-03-2018 CDW54_RS08075 feb449320878a779c22088ded7643cf5 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 1.6E-49 T 28-03-2018 CDW54_RS08075 feb449320878a779c22088ded7643cf5 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 123 132 1.6E-49 T 28-03-2018 CDW54_RS08075 feb449320878a779c22088ded7643cf5 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 248 262 1.6E-49 T 28-03-2018 CDW54_RS08075 feb449320878a779c22088ded7643cf5 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 1.6E-49 T 28-03-2018 CDW54_RS08075 feb449320878a779c22088ded7643cf5 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 393 408 1.6E-49 T 28-03-2018 CDW54_RS08075 feb449320878a779c22088ded7643cf5 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 160 178 1.3E-25 T 28-03-2018 CDW54_RS08075 feb449320878a779c22088ded7643cf5 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 247 263 1.3E-25 T 28-03-2018 CDW54_RS08075 feb449320878a779c22088ded7643cf5 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.3E-25 T 28-03-2018 CDW54_RS08075 feb449320878a779c22088ded7643cf5 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 276 298 1.3E-25 T 28-03-2018 CDW54_RS08075 feb449320878a779c22088ded7643cf5 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 120 138 1.3E-25 T 28-03-2018 CDW54_RS08075 feb449320878a779c22088ded7643cf5 442 SUPERFAMILY SSF55424 328 440 3.09E-31 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CDW54_RS08075 feb449320878a779c22088ded7643cf5 442 SUPERFAMILY SSF51905 2 355 3.56E-49 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS08075 feb449320878a779c22088ded7643cf5 442 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 300 5.0E-57 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS08075 feb449320878a779c22088ded7643cf5 442 Gene3D G3DSA:3.40.50.720 147 314 7.2E-37 T 28-03-2018 CDW54_RS08075 feb449320878a779c22088ded7643cf5 442 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 40 50 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CDW54_RS08075 feb449320878a779c22088ded7643cf5 442 PIRSF PIRSF000350 1 441 2.1E-79 T 28-03-2018 CDW54_RS08075 feb449320878a779c22088ded7643cf5 442 Gene3D G3DSA:3.50.50.60 3 146 3.9E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS08075 feb449320878a779c22088ded7643cf5 442 Gene3D G3DSA:3.30.390.30 316 442 5.0E-29 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CDW54_RS02000 10442af293427e5054afb6fbf939f46a 109 Pfam PF16110 Domain of unknown function (DUF4828) 32 105 7.2E-26 T 28-03-2018 IPR032254 Protein of unknown function DUF4828 CDW54_RS11690 e7083dcaebbf0397e2aca72ee92707e1 333 Pfam PF07859 alpha/beta hydrolase fold 95 301 4.2E-19 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CDW54_RS11690 e7083dcaebbf0397e2aca72ee92707e1 333 SUPERFAMILY SSF53474 61 333 1.41E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CDW54_RS11690 e7083dcaebbf0397e2aca72ee92707e1 333 Gene3D G3DSA:3.40.50.1820 30 296 8.3E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CDW54_RS10790 a4c5c3866e8a4b3fee8a9bb777902bf3 315 Pfam PF00696 Amino acid kinase family 5 294 1.9E-32 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CDW54_RS10790 a4c5c3866e8a4b3fee8a9bb777902bf3 315 TIGRFAM TIGR00746 arcC: carbamate kinase 4 313 4.8E-133 T 28-03-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 CDW54_RS10790 a4c5c3866e8a4b3fee8a9bb777902bf3 315 PRINTS PR01469 Bacterial carbamate kinase signature 183 201 1.3E-63 T 28-03-2018 CDW54_RS10790 a4c5c3866e8a4b3fee8a9bb777902bf3 315 PRINTS PR01469 Bacterial carbamate kinase signature 110 129 1.3E-63 T 28-03-2018 CDW54_RS10790 a4c5c3866e8a4b3fee8a9bb777902bf3 315 PRINTS PR01469 Bacterial carbamate kinase signature 43 62 1.3E-63 T 28-03-2018 CDW54_RS10790 a4c5c3866e8a4b3fee8a9bb777902bf3 315 PRINTS PR01469 Bacterial carbamate kinase signature 160 179 1.3E-63 T 28-03-2018 CDW54_RS10790 a4c5c3866e8a4b3fee8a9bb777902bf3 315 PRINTS PR01469 Bacterial carbamate kinase signature 213 228 1.3E-63 T 28-03-2018 CDW54_RS10790 a4c5c3866e8a4b3fee8a9bb777902bf3 315 PRINTS PR01469 Bacterial carbamate kinase signature 75 93 1.3E-63 T 28-03-2018 CDW54_RS10790 a4c5c3866e8a4b3fee8a9bb777902bf3 315 PRINTS PR01469 Bacterial carbamate kinase signature 268 283 1.3E-63 T 28-03-2018 CDW54_RS10790 a4c5c3866e8a4b3fee8a9bb777902bf3 315 SUPERFAMILY SSF53633 4 312 7.72E-87 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CDW54_RS10790 a4c5c3866e8a4b3fee8a9bb777902bf3 315 PIRSF PIRSF000723 2 314 3.5E-121 T 28-03-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 CDW54_RS10790 a4c5c3866e8a4b3fee8a9bb777902bf3 315 Gene3D G3DSA:3.40.1160.10 1 314 2.9E-55 T 28-03-2018 CDW54_RS09765 b2e740b5d75c5ec705fc11d4297c6dd3 297 PIRSF PIRSF003097 2 297 7.5E-78 T 28-03-2018 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 CDW54_RS09765 b2e740b5d75c5ec705fc11d4297c6dd3 297 Pfam PF02687 FtsX-like permease family 200 296 4.6E-7 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CDW54_RS09765 b2e740b5d75c5ec705fc11d4297c6dd3 297 Gene3D G3DSA:1.10.287.70 10 293 0.18 T 28-03-2018 CDW54_RS00210 45da343216409558a1231afe5fd819c3 348 Gene3D G3DSA:3.40.50.300 3 149 1.1E-25 T 28-03-2018 CDW54_RS00210 45da343216409558a1231afe5fd819c3 348 Pfam PF06144 DNA polymerase III, delta subunit 23 199 3.9E-43 T 28-03-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 CDW54_RS00210 45da343216409558a1231afe5fd819c3 348 Gene3D G3DSA:1.10.8.60 152 230 1.6E-18 T 28-03-2018 CDW54_RS00210 45da343216409558a1231afe5fd819c3 348 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 19 340 1.8E-79 T 28-03-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 CDW54_RS00210 45da343216409558a1231afe5fd819c3 348 SUPERFAMILY SSF52540 10 218 5.31E-21 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS00210 45da343216409558a1231afe5fd819c3 348 Gene3D G3DSA:1.20.272.10 231 345 5.5E-28 T 28-03-2018 CDW54_RS00210 45da343216409558a1231afe5fd819c3 348 SUPERFAMILY SSF48019 223 340 3.57E-23 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CDW54_RS04595 00384178a4a67f9c50c83a142c44f628 222 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 55 5.5E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDW54_RS04595 00384178a4a67f9c50c83a142c44f628 222 SUPERFAMILY SSF46689 7 64 9.48E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDW54_RS04595 00384178a4a67f9c50c83a142c44f628 222 Gene3D G3DSA:1.10.10.60 5 62 3.5E-11 T 28-03-2018 CDW54_RS04595 00384178a4a67f9c50c83a142c44f628 222 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 67 211 2.4E-11 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 CDW54_RS04595 00384178a4a67f9c50c83a142c44f628 222 Gene3D G3DSA:1.10.357.10 63 218 2.2E-13 T 28-03-2018 CDW54_RS04595 00384178a4a67f9c50c83a142c44f628 222 SUPERFAMILY SSF48498 73 218 2.89E-32 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CDW54_RS09255 b8acbdfccc0db344caedff5250aec97b 241 Pfam PF13930 DNA/RNA non-specific endonuclease 79 208 5.8E-37 T 28-03-2018 CDW54_RS05210 903582d3323c5885d886aad8963195e9 256 PIRSF PIRSF006648 7 252 2.2E-23 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CDW54_RS05210 903582d3323c5885d886aad8963195e9 256 PRINTS PR00164 ABC-2 type transport system membrane protein signature 138 162 2.9E-7 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CDW54_RS05210 903582d3323c5885d886aad8963195e9 256 PRINTS PR00164 ABC-2 type transport system membrane protein signature 176 195 2.9E-7 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CDW54_RS05210 903582d3323c5885d886aad8963195e9 256 PRINTS PR00164 ABC-2 type transport system membrane protein signature 196 215 2.9E-7 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CDW54_RS05210 903582d3323c5885d886aad8963195e9 256 PRINTS PR00164 ABC-2 type transport system membrane protein signature 58 80 2.9E-7 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CDW54_RS05210 903582d3323c5885d886aad8963195e9 256 Pfam PF01061 ABC-2 type transporter 8 218 3.6E-37 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CDW54_RS01780 5a884605e592083c4c5a55604b1e566b 315 SUPERFAMILY SSF51735 3 312 3.94E-84 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS01780 5a884605e592083c4c5a55604b1e566b 315 Gene3D G3DSA:3.90.25.10 175 314 3.8E-37 T 28-03-2018 CDW54_RS01780 5a884605e592083c4c5a55604b1e566b 315 Gene3D G3DSA:3.40.50.720 3 174 9.1E-34 T 28-03-2018 CDW54_RS01780 5a884605e592083c4c5a55604b1e566b 315 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 247 1.7E-61 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CDW54_RS03245 c36d920299d95d632b5cb88049874af6 367 SUPERFAMILY SSF56796 6 352 3.01E-53 T 28-03-2018 CDW54_RS03245 c36d920299d95d632b5cb88049874af6 367 PIRSF PIRSF000112 2 356 1.0E-74 T 28-03-2018 CDW54_RS03245 c36d920299d95d632b5cb88049874af6 367 Gene3D G3DSA:1.20.1090.10 160 358 2.1E-27 T 28-03-2018 CDW54_RS03245 c36d920299d95d632b5cb88049874af6 367 Gene3D G3DSA:3.40.50.1970 2 159 9.6E-23 T 28-03-2018 CDW54_RS03245 c36d920299d95d632b5cb88049874af6 367 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 342 4.3E-40 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CDW54_RS06045 3b390f12830f4ff1cd8d56761930ee35 129 ProSitePatterns PS00054 Ribosomal protein S11 signature. 97 119 - T 28-03-2018 IPR018102 Ribosomal S11, conserved site CDW54_RS06045 3b390f12830f4ff1cd8d56761930ee35 129 Pfam PF00411 Ribosomal protein S11 19 128 8.5E-50 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CDW54_RS06045 3b390f12830f4ff1cd8d56761930ee35 129 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 4 129 33.193 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CDW54_RS06045 3b390f12830f4ff1cd8d56761930ee35 129 Gene3D G3DSA:3.30.420.80 3 129 5.6E-43 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CDW54_RS06045 3b390f12830f4ff1cd8d56761930ee35 129 PIRSF PIRSF002131 1 129 6.2E-51 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CDW54_RS06045 3b390f12830f4ff1cd8d56761930ee35 129 SUPERFAMILY SSF53137 14 129 1.05E-47 T 28-03-2018 CDW54_RS06045 3b390f12830f4ff1cd8d56761930ee35 129 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 10 126 6.0E-58 T 28-03-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS06730 42640ebec836c400b1b51754d57bac3b 361 SUPERFAMILY SSF55060 211 352 3.84E-35 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CDW54_RS06730 42640ebec836c400b1b51754d57bac3b 361 Gene3D G3DSA:3.30.70.890 218 359 1.8E-27 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CDW54_RS06730 42640ebec836c400b1b51754d57bac3b 361 SUPERFAMILY SSF54211 1 227 1.75E-50 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CDW54_RS06730 42640ebec836c400b1b51754d57bac3b 361 Pfam PF08544 GHMP kinases C terminal 259 331 5.9E-9 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CDW54_RS06730 42640ebec836c400b1b51754d57bac3b 361 PRINTS PR00959 Mevalonate kinase family signature 109 131 2.0E-8 T 28-03-2018 CDW54_RS06730 42640ebec836c400b1b51754d57bac3b 361 PRINTS PR00959 Mevalonate kinase family signature 311 328 2.0E-8 T 28-03-2018 CDW54_RS06730 42640ebec836c400b1b51754d57bac3b 361 PRINTS PR00959 Mevalonate kinase family signature 6 30 2.0E-8 T 28-03-2018 CDW54_RS06730 42640ebec836c400b1b51754d57bac3b 361 Gene3D G3DSA:3.30.230.10 1 217 1.0E-44 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CDW54_RS06730 42640ebec836c400b1b51754d57bac3b 361 TIGRFAM TIGR01220 Pmev_kin_Gr_pos: phosphomevalonate kinase 2 355 5.4E-164 T 28-03-2018 IPR005917 Phosphomevalonate kinase KEGG: 00900+2.7.4.2|MetaCyc: PWY-7391|MetaCyc: PWY-922 CDW54_RS06730 42640ebec836c400b1b51754d57bac3b 361 Pfam PF00288 GHMP kinases N terminal domain 102 171 1.2E-13 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CDW54_RS11000 7b85d31dde7405bf60541ae2ff102703 245 SMART SM00382 29 216 1.1E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS11000 7b85d31dde7405bf60541ae2ff102703 245 PIRSF PIRSF039085 1 244 6.5E-117 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CDW54_RS11000 7b85d31dde7405bf60541ae2ff102703 245 Gene3D G3DSA:3.40.50.300 1 243 6.3E-78 T 28-03-2018 CDW54_RS11000 7b85d31dde7405bf60541ae2ff102703 245 Pfam PF00005 ABC transporter 20 168 1.7E-38 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS11000 7b85d31dde7405bf60541ae2ff102703 245 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS11000 7b85d31dde7405bf60541ae2ff102703 245 SUPERFAMILY SSF52540 6 238 6.55E-82 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS09465 40a22d6ecdbbd8fa4e7db57c0463c8f0 458 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 10 74 4.6E-12 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CDW54_RS09465 40a22d6ecdbbd8fa4e7db57c0463c8f0 458 SUPERFAMILY SSF47917 362 425 1.28E-5 T 28-03-2018 CDW54_RS09465 40a22d6ecdbbd8fa4e7db57c0463c8f0 458 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 340 349 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CDW54_RS09465 40a22d6ecdbbd8fa4e7db57c0463c8f0 458 Hamap MF_00310 V-type ATP synthase beta chain [atpB]. 2 458 61.07 T 28-03-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CDW54_RS09465 40a22d6ecdbbd8fa4e7db57c0463c8f0 458 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 131 349 8.6E-67 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CDW54_RS09465 40a22d6ecdbbd8fa4e7db57c0463c8f0 458 Gene3D G3DSA:1.10.1140.10 358 458 2.3E-18 T 28-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CDW54_RS09465 40a22d6ecdbbd8fa4e7db57c0463c8f0 458 SUPERFAMILY SSF52540 78 353 3.56E-82 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS09465 40a22d6ecdbbd8fa4e7db57c0463c8f0 458 Gene3D G3DSA:3.40.50.300 28 349 3.8E-83 T 28-03-2018 CDW54_RS09465 40a22d6ecdbbd8fa4e7db57c0463c8f0 458 PIRSF PIRSF039114 1 458 2.0E-243 T 28-03-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CDW54_RS03565 ae2b9a469a98c7facce67c5c7b1a62e3 507 SUPERFAMILY SSF51011 379 506 6.83E-34 T 28-03-2018 CDW54_RS03565 ae2b9a469a98c7facce67c5c7b1a62e3 507 Pfam PF06964 Alpha-L-arabinofuranosidase C-terminal domain 304 498 1.7E-27 T 28-03-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 CDW54_RS03565 ae2b9a469a98c7facce67c5c7b1a62e3 507 SUPERFAMILY SSF51445 18 390 7.42E-95 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CDW54_RS03565 ae2b9a469a98c7facce67c5c7b1a62e3 507 Gene3D G3DSA:3.20.20.80 19 382 2.8E-96 T 28-03-2018 CDW54_RS03565 ae2b9a469a98c7facce67c5c7b1a62e3 507 SMART SM00813 304 498 9.3E-61 T 28-03-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 CDW54_RS03565 ae2b9a469a98c7facce67c5c7b1a62e3 507 Gene3D G3DSA:2.60.40.1180 383 507 1.6E-27 T 28-03-2018 CDW54_RS05920 602018acfaa85785ae29fe6d73c80983 209 SUPERFAMILY SSF50447 1 207 1.59E-81 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CDW54_RS05920 602018acfaa85785ae29fe6d73c80983 209 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 206 39.504 T 28-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS05920 602018acfaa85785ae29fe6d73c80983 209 ProSitePatterns PS00474 Ribosomal protein L3 signature. 102 125 - T 28-03-2018 IPR019926 Ribosomal protein L3, conserved site CDW54_RS05920 602018acfaa85785ae29fe6d73c80983 209 Pfam PF00297 Ribosomal protein L3 99 181 4.1E-17 T 28-03-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS05920 602018acfaa85785ae29fe6d73c80983 209 Gene3D G3DSA:4.10.960.10 59 164 4.3E-34 T 28-03-2018 CDW54_RS05920 602018acfaa85785ae29fe6d73c80983 209 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 4 203 5.4E-86 T 28-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS11455 2100e1818003d8e94f76203443f900f2 146 Gene3D G3DSA:2.40.50.140 41 140 1.2E-5 T 28-03-2018 CDW54_RS10565 415997c6b57e2c63bc91f739b104d678 392 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 163 357 1.0E-30 T 28-03-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 CDW54_RS10565 415997c6b57e2c63bc91f739b104d678 392 SUPERFAMILY SSF88697 1 66 5.47E-20 T 28-03-2018 IPR015947 PUA-like domain CDW54_RS10565 415997c6b57e2c63bc91f739b104d678 392 SUPERFAMILY SSF53335 75 385 2.79E-65 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDW54_RS10565 415997c6b57e2c63bc91f739b104d678 392 Gene3D G3DSA:3.30.750.80 67 163 3.4E-21 T 28-03-2018 CDW54_RS10565 415997c6b57e2c63bc91f739b104d678 392 Gene3D G3DSA:3.40.50.150 164 388 3.5E-26 T 28-03-2018 CDW54_RS10565 415997c6b57e2c63bc91f739b104d678 392 Gene3D G3DSA:2.30.130.10 2 63 2.3E-19 T 28-03-2018 IPR002478 PUA domain GO:0003723 CDW54_RS12375 f2faab49a332ca5f4376d1196ac604f3 358 Gene3D G3DSA:3.40.50.880 141 357 2.9E-54 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CDW54_RS12375 f2faab49a332ca5f4376d1196ac604f3 358 Gene3D G3DSA:3.50.30.20 1 140 2.3E-59 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDW54_RS12375 f2faab49a332ca5f4376d1196ac604f3 358 PRINTS PR00096 Glutamine amidotransferase superfamily signature 214 223 1.0E-11 T 28-03-2018 CDW54_RS12375 f2faab49a332ca5f4376d1196ac604f3 358 PRINTS PR00096 Glutamine amidotransferase superfamily signature 241 252 1.0E-11 T 28-03-2018 CDW54_RS12375 f2faab49a332ca5f4376d1196ac604f3 358 PRINTS PR00096 Glutamine amidotransferase superfamily signature 327 340 1.0E-11 T 28-03-2018 CDW54_RS12375 f2faab49a332ca5f4376d1196ac604f3 358 PRINTS PR00097 Anthranilate synthase component II signature 214 223 9.8E-7 T 28-03-2018 CDW54_RS12375 f2faab49a332ca5f4376d1196ac604f3 358 PRINTS PR00097 Anthranilate synthase component II signature 241 252 9.8E-7 T 28-03-2018 CDW54_RS12375 f2faab49a332ca5f4376d1196ac604f3 358 PRINTS PR00097 Anthranilate synthase component II signature 327 340 9.8E-7 T 28-03-2018 CDW54_RS12375 f2faab49a332ca5f4376d1196ac604f3 358 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 4 353 2.7E-151 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDW54_RS12375 f2faab49a332ca5f4376d1196ac604f3 358 SMART SM01097 1 131 1.6E-90 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDW54_RS12375 f2faab49a332ca5f4376d1196ac604f3 358 SUPERFAMILY SSF52021 1 144 2.35E-57 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDW54_RS12375 f2faab49a332ca5f4376d1196ac604f3 358 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 1 356 48.985 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDW54_RS12375 f2faab49a332ca5f4376d1196ac604f3 358 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 172 186 4.5E-38 T 28-03-2018 CDW54_RS12375 f2faab49a332ca5f4376d1196ac604f3 358 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 258 275 4.5E-38 T 28-03-2018 CDW54_RS12375 f2faab49a332ca5f4376d1196ac604f3 358 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 241 257 4.5E-38 T 28-03-2018 CDW54_RS12375 f2faab49a332ca5f4376d1196ac604f3 358 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 283 294 4.5E-38 T 28-03-2018 CDW54_RS12375 f2faab49a332ca5f4376d1196ac604f3 358 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 211 225 4.5E-38 T 28-03-2018 CDW54_RS12375 f2faab49a332ca5f4376d1196ac604f3 358 Pfam PF00117 Glutamine amidotransferase class-I 174 350 6.7E-47 T 28-03-2018 IPR017926 Glutamine amidotransferase CDW54_RS12375 f2faab49a332ca5f4376d1196ac604f3 358 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 3 130 2.2E-53 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDW54_RS12375 f2faab49a332ca5f4376d1196ac604f3 358 SUPERFAMILY SSF52317 140 353 3.48E-59 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CDW54_RS06530 4f5e454e03d331680900db91f981b8ba 209 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 8 193 8.1E-47 T 28-03-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Reactome: R-HSA-73614 CDW54_RS06530 4f5e454e03d331680900db91f981b8ba 209 TIGRFAM TIGR00235 udk: uridine kinase 1 206 1.0E-92 T 28-03-2018 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|Reactome: R-HSA-73614 CDW54_RS06530 4f5e454e03d331680900db91f981b8ba 209 Hamap MF_00551 Uridine kinase [udk]. 3 207 41.852 T 28-03-2018 IPR026008 Uridine kinase GO:0004849|GO:0005524|GO:0016773 KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 CDW54_RS06530 4f5e454e03d331680900db91f981b8ba 209 Gene3D G3DSA:3.40.50.300 1 209 9.5E-63 T 28-03-2018 CDW54_RS06530 4f5e454e03d331680900db91f981b8ba 209 PRINTS PR00988 Uridine kinase signature 151 162 1.0E-38 T 28-03-2018 CDW54_RS06530 4f5e454e03d331680900db91f981b8ba 209 PRINTS PR00988 Uridine kinase signature 137 147 1.0E-38 T 28-03-2018 CDW54_RS06530 4f5e454e03d331680900db91f981b8ba 209 PRINTS PR00988 Uridine kinase signature 81 96 1.0E-38 T 28-03-2018 CDW54_RS06530 4f5e454e03d331680900db91f981b8ba 209 PRINTS PR00988 Uridine kinase signature 6 23 1.0E-38 T 28-03-2018 CDW54_RS06530 4f5e454e03d331680900db91f981b8ba 209 PRINTS PR00988 Uridine kinase signature 36 47 1.0E-38 T 28-03-2018 CDW54_RS06530 4f5e454e03d331680900db91f981b8ba 209 PRINTS PR00988 Uridine kinase signature 173 186 1.0E-38 T 28-03-2018 CDW54_RS06530 4f5e454e03d331680900db91f981b8ba 209 SUPERFAMILY SSF52540 3 198 3.06E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS07085 fcc65babd27d2abd8d4913f3a233e209 471 Gene3D G3DSA:3.20.20.80 3 463 1.7E-114 T 28-03-2018 CDW54_RS07085 fcc65babd27d2abd8d4913f3a233e209 471 PRINTS PR00131 Glycosyl hydrolase family 1 signature 386 397 8.0E-12 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS07085 fcc65babd27d2abd8d4913f3a233e209 471 PRINTS PR00131 Glycosyl hydrolase family 1 signature 407 424 8.0E-12 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS07085 fcc65babd27d2abd8d4913f3a233e209 471 PRINTS PR00131 Glycosyl hydrolase family 1 signature 290 304 8.0E-12 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS07085 fcc65babd27d2abd8d4913f3a233e209 471 PRINTS PR00131 Glycosyl hydrolase family 1 signature 431 443 8.0E-12 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS07085 fcc65babd27d2abd8d4913f3a233e209 471 PRINTS PR00131 Glycosyl hydrolase family 1 signature 362 370 8.0E-12 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS07085 fcc65babd27d2abd8d4913f3a233e209 471 SUPERFAMILY SSF51445 2 458 5.64E-133 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CDW54_RS07085 fcc65babd27d2abd8d4913f3a233e209 471 Pfam PF00232 Glycosyl hydrolase family 1 3 461 4.1E-98 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS07655 19d8cfff9eab91ee45ef33a137cd42dd 222 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 219 2.4E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDW54_RS07655 19d8cfff9eab91ee45ef33a137cd42dd 222 Gene3D G3DSA:1.10.10.10 120 221 5.6E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS07655 19d8cfff9eab91ee45ef33a137cd42dd 222 SMART SM00862 146 220 3.8E-17 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDW54_RS07655 19d8cfff9eab91ee45ef33a137cd42dd 222 SUPERFAMILY SSF52172 2 174 9.39E-44 T 28-03-2018 IPR011006 CheY-like superfamily CDW54_RS07655 19d8cfff9eab91ee45ef33a137cd42dd 222 SMART SM00448 2 113 3.7E-40 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDW54_RS07655 19d8cfff9eab91ee45ef33a137cd42dd 222 Pfam PF00072 Response regulator receiver domain 4 113 3.0E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDW54_RS07655 19d8cfff9eab91ee45ef33a137cd42dd 222 Gene3D G3DSA:3.40.50.2300 2 119 3.2E-37 T 28-03-2018 CDW54_RS10360 c9cfbd91868a4a413498a3942c667a8b 234 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 229 2.1E-26 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDW54_RS10360 c9cfbd91868a4a413498a3942c667a8b 234 SMART SM00862 153 229 1.9E-27 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDW54_RS10360 c9cfbd91868a4a413498a3942c667a8b 234 SMART SM00448 2 113 8.1E-46 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDW54_RS10360 c9cfbd91868a4a413498a3942c667a8b 234 Pfam PF00072 Response regulator receiver domain 4 113 5.4E-32 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDW54_RS10360 c9cfbd91868a4a413498a3942c667a8b 234 SUPERFAMILY SSF46894 129 230 7.09E-32 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDW54_RS10360 c9cfbd91868a4a413498a3942c667a8b 234 Gene3D G3DSA:1.10.10.10 131 234 4.6E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS10360 c9cfbd91868a4a413498a3942c667a8b 234 Gene3D G3DSA:3.40.50.2300 1 130 3.3E-39 T 28-03-2018 CDW54_RS10360 c9cfbd91868a4a413498a3942c667a8b 234 SUPERFAMILY SSF52172 1 127 4.13E-43 T 28-03-2018 IPR011006 CheY-like superfamily CDW54_RS04505 64e4facb49b260e0f8009dcbdf16795e 97 SUPERFAMILY SSF54909 3 94 1.86E-18 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CDW54_RS04505 64e4facb49b260e0f8009dcbdf16795e 97 Gene3D G3DSA:3.30.70.100 3 97 6.4E-14 T 28-03-2018 CDW54_RS04505 64e4facb49b260e0f8009dcbdf16795e 97 Pfam PF03992 Antibiotic biosynthesis monooxygenase 3 79 7.7E-13 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CDW54_RS11680 76f1f060235092551bc0c47082073815 168 SUPERFAMILY SSF52499 7 164 1.01E-35 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CDW54_RS11680 76f1f060235092551bc0c47082073815 168 Gene3D G3DSA:3.40.50.850 2 168 5.8E-27 T 28-03-2018 CDW54_RS11680 76f1f060235092551bc0c47082073815 168 Pfam PF00857 Isochorismatase family 7 144 6.2E-23 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CDW54_RS07040 c649dcc635fb20ce8f563a1655b16bf5 211 Pfam PF06197 Protein of unknown function (DUF998) 14 204 8.2E-13 T 28-03-2018 IPR009339 Protein of unknown function DUF998 CDW54_RS01480 f86aec5fe9f99d957b245cb40f747873 239 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 1 237 30.925 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDW54_RS01480 f86aec5fe9f99d957b245cb40f747873 239 Pfam PF01709 Transcriptional regulator 4 235 5.2E-80 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDW54_RS01480 f86aec5fe9f99d957b245cb40f747873 239 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 235 9.6E-70 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDW54_RS01480 f86aec5fe9f99d957b245cb40f747873 239 Hamap MF_00918 Probable transcriptional regulatory protein YeeN [yeeN]. 1 238 55.574 T 28-03-2018 IPR026562 Probable transcriptional regulatory protein YeeN CDW54_RS01480 f86aec5fe9f99d957b245cb40f747873 239 Gene3D G3DSA:3.30.70.980 175 239 2.9E-10 T 28-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDW54_RS01480 f86aec5fe9f99d957b245cb40f747873 239 SUPERFAMILY SSF75625 1 238 4.71E-80 T 28-03-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDW54_RS01480 f86aec5fe9f99d957b245cb40f747873 239 Gene3D G3DSA:1.10.10.200 2 76 3.1E-24 T 28-03-2018 IPR017856 Integrase, N-terminal zinc-binding domain-like CDW54_RS01480 f86aec5fe9f99d957b245cb40f747873 239 Gene3D G3DSA:3.30.70.980 80 174 9.3E-26 T 28-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDW54_RS01220 434d6f42854025f02c3f56fe3439264a 275 Gene3D G3DSA:1.25.40.10 107 265 2.1E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDW54_RS01220 434d6f42854025f02c3f56fe3439264a 275 SMART SM00530 8 62 1.2E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDW54_RS01220 434d6f42854025f02c3f56fe3439264a 275 SUPERFAMILY SSF48452 86 252 6.75E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDW54_RS01220 434d6f42854025f02c3f56fe3439264a 275 Pfam PF01381 Helix-turn-helix 9 61 1.9E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDW54_RS01220 434d6f42854025f02c3f56fe3439264a 275 SUPERFAMILY SSF47413 6 63 5.91E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDW54_RS01220 434d6f42854025f02c3f56fe3439264a 275 Pfam PF13181 Tetratricopeptide repeat 191 222 2.6E-4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDW54_RS01220 434d6f42854025f02c3f56fe3439264a 275 SMART SM00028 148 181 70.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDW54_RS01220 434d6f42854025f02c3f56fe3439264a 275 SMART SM00028 189 222 2.4E-4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDW54_RS01220 434d6f42854025f02c3f56fe3439264a 275 Gene3D G3DSA:1.10.3100.10 2 106 1.5E-18 T 28-03-2018 IPR027910 YdiL-like domain CDW54_RS02540 bf86a736f026809c42f5349e6ed61e9e 559 SMART SM00849 22 216 2.0E-21 T 28-03-2018 IPR001279 Metallo-beta-lactamase CDW54_RS02540 bf86a736f026809c42f5349e6ed61e9e 559 Hamap MF_01491 Ribonuclease J [rnj]. 5 556 45.636 T 28-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CDW54_RS02540 bf86a736f026809c42f5349e6ed61e9e 559 PIRSF PIRSF004803 1 556 3.8E-227 T 28-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CDW54_RS02540 bf86a736f026809c42f5349e6ed61e9e 559 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 365 393 - T 28-03-2018 IPR001587 Ribonuclease J, conserved site CDW54_RS02540 bf86a736f026809c42f5349e6ed61e9e 559 Pfam PF00753 Metallo-beta-lactamase superfamily 21 168 4.0E-16 T 28-03-2018 IPR001279 Metallo-beta-lactamase CDW54_RS02540 bf86a736f026809c42f5349e6ed61e9e 559 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 359 409 3.9E-12 T 28-03-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain CDW54_RS02540 bf86a736f026809c42f5349e6ed61e9e 559 SUPERFAMILY SSF56281 13 424 1.41E-90 T 28-03-2018 IPR001279 Metallo-beta-lactamase CDW54_RS02540 bf86a736f026809c42f5349e6ed61e9e 559 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 12 554 3.7E-204 T 28-03-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 CDW54_RS02540 bf86a736f026809c42f5349e6ed61e9e 559 Gene3D G3DSA:3.60.15.10 4 449 1.2E-61 T 28-03-2018 IPR001279 Metallo-beta-lactamase CDW54_RS08905 f5b572dd38bf8c4df6f66101458efe83 446 PIRSF PIRSF006060 1 444 2.8E-48 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CDW54_RS08905 f5b572dd38bf8c4df6f66101458efe83 446 Pfam PF00324 Amino acid permease 14 429 3.3E-72 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CDW54_RS05215 7dc1d271cb5293d9e009a845e8e3909e 311 SMART SM00382 30 212 2.8E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS05215 7dc1d271cb5293d9e009a845e8e3909e 311 Pfam PF00005 ABC transporter 21 165 4.3E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS05215 7dc1d271cb5293d9e009a845e8e3909e 311 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS05215 7dc1d271cb5293d9e009a845e8e3909e 311 SUPERFAMILY SSF52540 4 233 2.24E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS05215 7dc1d271cb5293d9e009a845e8e3909e 311 Gene3D G3DSA:3.40.50.300 1 310 4.3E-63 T 28-03-2018 CDW54_RS00315 1dbcd9795e2e5f1664deeb92a68d80ec 325 SUPERFAMILY SSF52518 2 204 1.06E-66 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CDW54_RS00315 1dbcd9795e2e5f1664deeb92a68d80ec 325 Pfam PF02780 Transketolase, C-terminal domain 195 315 6.8E-38 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CDW54_RS00315 1dbcd9795e2e5f1664deeb92a68d80ec 325 Gene3D G3DSA:3.40.50.920 195 324 3.0E-34 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CDW54_RS00315 1dbcd9795e2e5f1664deeb92a68d80ec 325 SUPERFAMILY SSF52922 189 323 2.36E-40 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CDW54_RS00315 1dbcd9795e2e5f1664deeb92a68d80ec 325 Gene3D G3DSA:3.40.50.970 1 194 4.7E-62 T 28-03-2018 CDW54_RS00315 1dbcd9795e2e5f1664deeb92a68d80ec 325 Pfam PF02779 Transketolase, pyrimidine binding domain 4 178 7.2E-41 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CDW54_RS00315 1dbcd9795e2e5f1664deeb92a68d80ec 325 SMART SM00861 4 179 2.3E-64 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CDW54_RS07425 14e39a820184dc848606ab5484fcb6f8 104 SMART SM00450 11 102 6.2E-22 T 28-03-2018 IPR001763 Rhodanese-like domain CDW54_RS07425 14e39a820184dc848606ab5484fcb6f8 104 SUPERFAMILY SSF52821 3 99 9.56E-31 T 28-03-2018 IPR001763 Rhodanese-like domain CDW54_RS07425 14e39a820184dc848606ab5484fcb6f8 104 Pfam PF00581 Rhodanese-like domain 15 96 2.0E-18 T 28-03-2018 IPR001763 Rhodanese-like domain CDW54_RS07425 14e39a820184dc848606ab5484fcb6f8 104 Gene3D G3DSA:3.40.250.10 4 101 2.3E-28 T 28-03-2018 IPR001763 Rhodanese-like domain CDW54_RS07565 1ef7c6d29b3d95c8c85a67b2d563996f 277 SUPERFAMILY SSF56219 1 276 3.01E-26 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CDW54_RS07565 1ef7c6d29b3d95c8c85a67b2d563996f 277 Gene3D G3DSA:3.60.10.10 1 274 7.5E-29 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CDW54_RS07565 1ef7c6d29b3d95c8c85a67b2d563996f 277 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 19 266 2.7E-10 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CDW54_RS01445 39b90bdd802537cce655f1f178780897 282 SUPERFAMILY SSF53697 96 266 1.71E-32 T 28-03-2018 CDW54_RS01445 39b90bdd802537cce655f1f178780897 282 Pfam PF01380 SIS domain 125 252 3.3E-13 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CDW54_RS01445 39b90bdd802537cce655f1f178780897 282 Gene3D G3DSA:1.10.10.10 1 77 3.4E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS01445 39b90bdd802537cce655f1f178780897 282 Pfam PF01418 Helix-turn-helix domain, rpiR family 1 76 1.1E-15 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CDW54_RS01445 39b90bdd802537cce655f1f178780897 282 Gene3D G3DSA:3.40.50.10490 87 279 5.5E-31 T 28-03-2018 CDW54_RS01445 39b90bdd802537cce655f1f178780897 282 SUPERFAMILY SSF46689 1 77 8.24E-20 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDW54_RS10760 97ffa2f79ab7ba0920a12f719469e1e6 180 SUPERFAMILY SSF55729 27 178 2.0E-32 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDW54_RS10760 97ffa2f79ab7ba0920a12f719469e1e6 180 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 40 173 1.2E-36 T 28-03-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 CDW54_RS10760 97ffa2f79ab7ba0920a12f719469e1e6 180 Pfam PF00583 Acetyltransferase (GNAT) family 58 153 8.0E-18 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CDW54_RS10760 97ffa2f79ab7ba0920a12f719469e1e6 180 Gene3D G3DSA:3.40.630.30 19 177 5.6E-32 T 28-03-2018 CDW54_RS07005 ef43b79f53837cfe8d38f69efde4035c 204 Gene3D G3DSA:3.40.630.30 1 191 4.2E-12 T 28-03-2018 CDW54_RS07005 ef43b79f53837cfe8d38f69efde4035c 204 Pfam PF00583 Acetyltransferase (GNAT) family 61 175 8.1E-6 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CDW54_RS07005 ef43b79f53837cfe8d38f69efde4035c 204 SUPERFAMILY SSF55729 1 82 3.87E-11 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDW54_RS07005 ef43b79f53837cfe8d38f69efde4035c 204 SUPERFAMILY SSF55729 115 181 3.87E-11 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDW54_RS11755 ddde984aeea600a789f2b7a5d5e70b40 269 Gene3D G3DSA:3.40.50.1000 1 269 5.4E-39 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS11755 ddde984aeea600a789f2b7a5d5e70b40 269 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 265 5.9E-55 T 28-03-2018 IPR000150 Cof family GO:0016787 CDW54_RS11755 ddde984aeea600a789f2b7a5d5e70b40 269 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 265 6.5E-62 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS11755 ddde984aeea600a789f2b7a5d5e70b40 269 SUPERFAMILY SSF56784 2 268 1.09E-60 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS11755 ddde984aeea600a789f2b7a5d5e70b40 269 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 238 6.0E-26 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CDW54_RS04045 ffe5983ab77de3f87b7b2d94380c57a2 589 Pfam PF00152 tRNA synthetases class II (D, K and N) 123 558 2.0E-109 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDW54_RS04045 ffe5983ab77de3f87b7b2d94380c57a2 589 Pfam PF01336 OB-fold nucleic acid binding domain 20 105 1.1E-17 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CDW54_RS04045 ffe5983ab77de3f87b7b2d94380c57a2 589 Gene3D G3DSA:3.30.930.10 136 587 1.8E-100 T 28-03-2018 CDW54_RS04045 ffe5983ab77de3f87b7b2d94380c57a2 589 PRINTS PR01042 Aspartyl-tRNA synthetase signature 195 207 1.5E-24 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDW54_RS04045 ffe5983ab77de3f87b7b2d94380c57a2 589 PRINTS PR01042 Aspartyl-tRNA synthetase signature 475 491 1.5E-24 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDW54_RS04045 ffe5983ab77de3f87b7b2d94380c57a2 589 PRINTS PR01042 Aspartyl-tRNA synthetase signature 519 533 1.5E-24 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDW54_RS04045 ffe5983ab77de3f87b7b2d94380c57a2 589 PRINTS PR01042 Aspartyl-tRNA synthetase signature 212 225 1.5E-24 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDW54_RS04045 ffe5983ab77de3f87b7b2d94380c57a2 589 SUPERFAMILY SSF50249 4 108 1.85E-32 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDW54_RS04045 ffe5983ab77de3f87b7b2d94380c57a2 589 SUPERFAMILY SSF55261 294 420 1.64E-41 T 28-03-2018 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 CDW54_RS04045 ffe5983ab77de3f87b7b2d94380c57a2 589 Pfam PF02938 GAD domain 313 406 6.7E-29 T 28-03-2018 IPR029351 GAD domain Reactome: R-HSA-379726 CDW54_RS04045 ffe5983ab77de3f87b7b2d94380c57a2 589 SUPERFAMILY SSF55681 115 297 1.61E-102 T 28-03-2018 CDW54_RS04045 ffe5983ab77de3f87b7b2d94380c57a2 589 SUPERFAMILY SSF55681 425 585 1.61E-102 T 28-03-2018 CDW54_RS04045 ffe5983ab77de3f87b7b2d94380c57a2 589 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 3 585 34.473 T 28-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 CDW54_RS04045 ffe5983ab77de3f87b7b2d94380c57a2 589 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 3 584 8.1E-248 T 28-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 CDW54_RS04045 ffe5983ab77de3f87b7b2d94380c57a2 589 Gene3D G3DSA:2.40.50.140 1 111 1.1E-26 T 28-03-2018 CDW54_RS06845 db79ea54c456a005a5d935978d3a01c7 159 Gene3D G3DSA:3.40.1280.10 1 159 1.3E-61 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CDW54_RS06845 db79ea54c456a005a5d935978d3a01c7 159 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 2 159 7.1E-61 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CDW54_RS06845 db79ea54c456a005a5d935978d3a01c7 159 SUPERFAMILY SSF75217 1 157 7.19E-60 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CDW54_RS06845 db79ea54c456a005a5d935978d3a01c7 159 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 159 30.315 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CDW54_RS06845 db79ea54c456a005a5d935978d3a01c7 159 Pfam PF02590 Predicted SPOUT methyltransferase 1 158 5.2E-59 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CDW54_RS06845 db79ea54c456a005a5d935978d3a01c7 159 PIRSF PIRSF004505 1 159 5.2E-54 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CDW54_RS03850 d99a1dffe0a1dec24c8d7d9e58a6547c 290 Gene3D G3DSA:1.10.4100.10 86 270 9.1E-30 T 28-03-2018 CDW54_RS03850 d99a1dffe0a1dec24c8d7d9e58a6547c 290 Pfam PF03313 Serine dehydratase alpha chain 17 273 7.4E-74 T 28-03-2018 IPR005130 Serine dehydratase-like, alpha subunit CDW54_RS03850 d99a1dffe0a1dec24c8d7d9e58a6547c 290 TIGRFAM TIGR00718 sda_alpha: L-serine dehydratase, iron-sulfur-dependent, alpha subunit 1 287 1.3E-110 T 28-03-2018 IPR004642 Serine dehydratase, alpha subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CDW54_RS01150 1db3cbc16f97a113649eb3aa459bc819 259 Gene3D G3DSA:1.10.10.10 11 87 1.6E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS01150 1db3cbc16f97a113649eb3aa459bc819 259 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 60 2.9E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDW54_RS01150 1db3cbc16f97a113649eb3aa459bc819 259 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 60 76 2.9E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDW54_RS01150 1db3cbc16f97a113649eb3aa459bc819 259 SUPERFAMILY SSF46785 18 90 2.57E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS01150 1db3cbc16f97a113649eb3aa459bc819 259 Pfam PF00392 Bacterial regulatory proteins, gntR family 23 86 1.4E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDW54_RS01150 1db3cbc16f97a113649eb3aa459bc819 259 SMART SM00345 27 86 1.3E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDW54_RS01150 1db3cbc16f97a113649eb3aa459bc819 259 SUPERFAMILY SSF64288 98 252 3.93E-41 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CDW54_RS01150 1db3cbc16f97a113649eb3aa459bc819 259 SMART SM00866 111 250 8.4E-34 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CDW54_RS01150 1db3cbc16f97a113649eb3aa459bc819 259 Gene3D G3DSA:3.40.1410.10 93 255 2.9E-34 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CDW54_RS01150 1db3cbc16f97a113649eb3aa459bc819 259 Pfam PF07702 UTRA domain 112 247 5.5E-33 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CDW54_RS03160 c82d56500d45061ec0051ee7adc28a37 189 TIGRFAM TIGR00334 5S_RNA_mat_M5: ribonuclease M5 5 181 7.5E-57 T 28-03-2018 IPR004466 Ribonuclease M5 GO:0043822 CDW54_RS03160 c82d56500d45061ec0051ee7adc28a37 189 SMART SM00493 7 80 9.1E-6 T 28-03-2018 IPR006171 TOPRIM domain CDW54_RS03160 c82d56500d45061ec0051ee7adc28a37 189 Pfam PF01751 Toprim domain 8 76 3.8E-5 T 28-03-2018 IPR006171 TOPRIM domain CDW54_RS03160 c82d56500d45061ec0051ee7adc28a37 189 Gene3D G3DSA:3.40.1360.20 3 128 3.4E-20 T 28-03-2018 CDW54_RS03160 c82d56500d45061ec0051ee7adc28a37 189 Hamap MF_01469 Ribonuclease M5 [rnmV]. 5 183 30.834 T 28-03-2018 IPR004466 Ribonuclease M5 GO:0043822 CDW54_RS03160 c82d56500d45061ec0051ee7adc28a37 189 Pfam PF13331 Domain of unknown function (DUF4093) 95 181 4.3E-29 T 28-03-2018 IPR025156 Ribonuclease M5, C-terminal domain CDW54_RS03160 c82d56500d45061ec0051ee7adc28a37 189 SUPERFAMILY SSF110455 4 119 1.28E-35 T 28-03-2018 CDW54_RS02410 6602e4d5be61dedb593f583e0dcdf425 286 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 283 1.0E-85 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CDW54_RS02410 6602e4d5be61dedb593f583e0dcdf425 286 Gene3D G3DSA:3.20.20.70 1 285 1.2E-95 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDW54_RS02410 6602e4d5be61dedb593f583e0dcdf425 286 SUPERFAMILY SSF51569 4 283 1.3E-94 T 28-03-2018 CDW54_RS02410 6602e4d5be61dedb593f583e0dcdf425 286 PIRSF PIRSF001359 1 283 1.4E-102 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CDW54_RS02410 6602e4d5be61dedb593f583e0dcdf425 286 Pfam PF01116 Fructose-bisphosphate aldolase class-II 4 282 1.1E-90 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CDW54_RS02410 6602e4d5be61dedb593f583e0dcdf425 286 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 69 82 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CDW54_RS07295 ccad57923a22ec0048cd0712c9d2feff 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 81 97 1.6E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDW54_RS07295 ccad57923a22ec0048cd0712c9d2feff 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 62 77 1.6E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDW54_RS07295 ccad57923a22ec0048cd0712c9d2feff 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 45 61 1.6E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDW54_RS07295 ccad57923a22ec0048cd0712c9d2feff 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 111 131 1.6E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDW54_RS07295 ccad57923a22ec0048cd0712c9d2feff 150 SUPERFAMILY SSF46785 4 143 4.09E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS07295 ccad57923a22ec0048cd0712c9d2feff 150 SMART SM00347 21 121 3.7E-20 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDW54_RS07295 ccad57923a22ec0048cd0712c9d2feff 150 Gene3D G3DSA:1.10.10.10 16 114 3.8E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS07295 ccad57923a22ec0048cd0712c9d2feff 150 Pfam PF01047 MarR family 28 85 5.5E-15 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDW54_RS08335 1e826bab68070d924ec0d8026b734a33 257 Pfam PF00005 ABC transporter 19 171 9.0E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS08335 1e826bab68070d924ec0d8026b734a33 257 SMART SM00382 28 254 2.0E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS08335 1e826bab68070d924ec0d8026b734a33 257 Gene3D G3DSA:3.40.50.300 1 249 2.1E-43 T 28-03-2018 CDW54_RS08335 1e826bab68070d924ec0d8026b734a33 257 SUPERFAMILY SSF52540 4 230 3.0E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS08335 1e826bab68070d924ec0d8026b734a33 257 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 4 242 5.6E-112 T 28-03-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524|GO:0006810 CDW54_RS08335 1e826bab68070d924ec0d8026b734a33 257 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS09785 1465d41a68ef59fa71489cd731dc9854 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 292 1.8E-35 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS09785 1465d41a68ef59fa71489cd731dc9854 294 SUPERFAMILY SSF161098 14 278 6.67E-37 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS09785 1465d41a68ef59fa71489cd731dc9854 294 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 7 287 4.7E-80 T 28-03-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 CDW54_RS09785 1465d41a68ef59fa71489cd731dc9854 294 Gene3D G3DSA:1.10.3720.10 1 281 6.6E-38 T 28-03-2018 CDW54_RS02175 8525bf6c7e2c49eb1be7b6c40f4b5a67 267 Pfam PF03609 PTS system sorbose-specific iic component 3 237 1.8E-73 T 28-03-2018 IPR004700 Phosphotransferase system, mannose/fructose/sorbose family, IIC subunit GO:0009401|GO:0016021 CDW54_RS11970 6286e85f5f5531866103c4dae9b3f3d5 136 SUPERFAMILY SSF82784 4 132 6.81E-32 T 28-03-2018 IPR003718 OsmC/Ohr family CDW54_RS11970 6286e85f5f5531866103c4dae9b3f3d5 136 Pfam PF02566 OsmC-like protein 39 131 7.7E-15 T 28-03-2018 IPR003718 OsmC/Ohr family CDW54_RS11970 6286e85f5f5531866103c4dae9b3f3d5 136 Gene3D G3DSA:3.30.300.20 1 136 5.7E-30 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CDW54_RS11970 6286e85f5f5531866103c4dae9b3f3d5 136 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 4 132 1.7E-45 T 28-03-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 CDW54_RS04880 75627e6390efddb43fd87ae97262f50e 299 Gene3D G3DSA:3.40.50.300 64 223 1.9E-21 T 28-03-2018 CDW54_RS04880 75627e6390efddb43fd87ae97262f50e 299 Pfam PF16745 RsgA N-terminal domain 5 58 6.1E-23 T 28-03-2018 IPR031944 Ribosome biogenesis GTPase RsgA, N-terminal CDW54_RS04880 75627e6390efddb43fd87ae97262f50e 299 Gene3D G3DSA:2.40.50.140 1 63 3.3E-19 T 28-03-2018 CDW54_RS04880 75627e6390efddb43fd87ae97262f50e 299 Pfam PF03193 RsgA GTPase 61 223 1.2E-57 T 28-03-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 CDW54_RS04880 75627e6390efddb43fd87ae97262f50e 299 Gene3D G3DSA:1.10.40.50 225 293 2.2E-21 T 28-03-2018 CDW54_RS04880 75627e6390efddb43fd87ae97262f50e 299 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 4 288 38.132 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 CDW54_RS04880 75627e6390efddb43fd87ae97262f50e 299 SUPERFAMILY SSF50249 4 65 3.31E-14 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDW54_RS04880 75627e6390efddb43fd87ae97262f50e 299 SUPERFAMILY SSF52540 66 288 1.03E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS04880 75627e6390efddb43fd87ae97262f50e 299 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 41 281 1.7E-75 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 CDW54_RS00205 5c4bbc8bec127e2add4ab3d196ff3390 84 Pfam PF01649 Ribosomal protein S20 2 82 1.3E-27 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS00205 5c4bbc8bec127e2add4ab3d196ff3390 84 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 84 16.204 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS00205 5c4bbc8bec127e2add4ab3d196ff3390 84 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 12 80 3.0E-27 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS00205 5c4bbc8bec127e2add4ab3d196ff3390 84 Gene3D G3DSA:1.20.58.110 1 84 5.4E-27 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS00205 5c4bbc8bec127e2add4ab3d196ff3390 84 SUPERFAMILY SSF46992 3 83 3.53E-26 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS00205 5c4bbc8bec127e2add4ab3d196ff3390 84 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 84 3.8E-23 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS11660 fda6a182f256d34577509698f59af4bf 231 SUPERFAMILY SSF51569 1 216 6.49E-56 T 28-03-2018 CDW54_RS11660 fda6a182f256d34577509698f59af4bf 231 Gene3D G3DSA:3.20.20.70 1 221 2.6E-47 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDW54_RS11660 fda6a182f256d34577509698f59af4bf 231 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 28-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CDW54_RS11660 fda6a182f256d34577509698f59af4bf 231 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 3 210 1.6E-40 T 28-03-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CDW54_RS01915 4f2ed656b34a6ffd12d073b1a986c964 146 SUPERFAMILY SSF52218 4 145 2.25E-37 T 28-03-2018 IPR029039 Flavoprotein-like domain CDW54_RS01915 4f2ed656b34a6ffd12d073b1a986c964 146 ProSitePatterns PS00201 Flavodoxin signature. 6 22 - T 28-03-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 CDW54_RS01915 4f2ed656b34a6ffd12d073b1a986c964 146 TIGRFAM TIGR01753 flav_short: flavodoxin 5 143 2.0E-43 T 28-03-2018 IPR010087 Flavodoxin, short chain GO:0010181 CDW54_RS01915 4f2ed656b34a6ffd12d073b1a986c964 146 Pfam PF00258 Flavodoxin 6 131 2.4E-22 T 28-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 CDW54_RS01915 4f2ed656b34a6ffd12d073b1a986c964 146 Gene3D G3DSA:3.40.50.360 3 146 1.6E-33 T 28-03-2018 IPR029039 Flavoprotein-like domain CDW54_RS04920 d25bb440800388651a3f7f2d53128ea4 204 SUPERFAMILY SSF52540 4 189 3.81E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS04920 d25bb440800388651a3f7f2d53128ea4 204 Pfam PF00625 Guanylate kinase 7 185 5.9E-51 T 28-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CDW54_RS04920 d25bb440800388651a3f7f2d53128ea4 204 Gene3D G3DSA:3.40.50.300 1 51 5.8E-10 T 28-03-2018 CDW54_RS04920 d25bb440800388651a3f7f2d53128ea4 204 SMART SM00072 4 187 5.0E-69 T 28-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CDW54_RS04920 d25bb440800388651a3f7f2d53128ea4 204 Gene3D G3DSA:3.40.50.300 84 187 7.9E-29 T 28-03-2018 CDW54_RS04920 d25bb440800388651a3f7f2d53128ea4 204 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 5 184 9.8E-74 T 28-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 CDW54_RS04920 d25bb440800388651a3f7f2d53128ea4 204 Hamap MF_00328 Guanylate kinase [gmk]. 3 187 36.922 T 28-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 CDW54_RS04920 d25bb440800388651a3f7f2d53128ea4 204 Gene3D G3DSA:3.30.63.10 52 83 2.9E-25 T 28-03-2018 CDW54_RS04920 d25bb440800388651a3f7f2d53128ea4 204 ProSitePatterns PS00856 Guanylate kinase-like signature. 40 57 - T 28-03-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 CDW54_RS07670 90223cea8ec43d9f818d093311e5289c 242 Pfam PF04474 Protein of unknown function (DUF554) 3 232 3.7E-65 T 28-03-2018 IPR007563 Protein of unknown function DUF554 CDW54_RS07335 428805f3de785764ad853f3637ff6ed8 591 SUPERFAMILY SSF46785 4 55 2.66E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS07335 428805f3de785764ad853f3637ff6ed8 591 Pfam PF08279 HTH domain 16 73 3.0E-7 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CDW54_RS07335 428805f3de785764ad853f3637ff6ed8 591 Gene3D G3DSA:1.10.10.10 80 173 1.6E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS07335 428805f3de785764ad853f3637ff6ed8 591 Gene3D G3DSA:1.10.10.10 4 76 1.6E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS08605 0a9931b1887ad25a80f3cbc0d29e0dbc 704 SMART SM01086 614 701 3.5E-30 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CDW54_RS08605 0a9931b1887ad25a80f3cbc0d29e0dbc 704 Gene3D G3DSA:3.40.50.300 77 263 2.4E-27 T 28-03-2018 CDW54_RS08605 0a9931b1887ad25a80f3cbc0d29e0dbc 704 SUPERFAMILY SSF52540 79 334 3.58E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS08605 0a9931b1887ad25a80f3cbc0d29e0dbc 704 Gene3D G3DSA:3.40.50.300 414 615 5.0E-34 T 28-03-2018 CDW54_RS08605 0a9931b1887ad25a80f3cbc0d29e0dbc 704 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 482 500 - T 28-03-2018 IPR028299 ClpA/B, conserved site 2 CDW54_RS08605 0a9931b1887ad25a80f3cbc0d29e0dbc 704 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 122 254 4.9E-13 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CDW54_RS08605 0a9931b1887ad25a80f3cbc0d29e0dbc 704 Gene3D G3DSA:1.10.8.60 264 398 3.1E-30 T 28-03-2018 CDW54_RS08605 0a9931b1887ad25a80f3cbc0d29e0dbc 704 SUPERFAMILY SSF52540 397 682 2.68E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS08605 0a9931b1887ad25a80f3cbc0d29e0dbc 704 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 614 684 1.1E-23 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CDW54_RS08605 0a9931b1887ad25a80f3cbc0d29e0dbc 704 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 497 515 3.1E-28 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CDW54_RS08605 0a9931b1887ad25a80f3cbc0d29e0dbc 704 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 527 545 3.1E-28 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CDW54_RS08605 0a9931b1887ad25a80f3cbc0d29e0dbc 704 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 560 574 3.1E-28 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CDW54_RS08605 0a9931b1887ad25a80f3cbc0d29e0dbc 704 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 452 470 3.1E-28 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CDW54_RS08605 0a9931b1887ad25a80f3cbc0d29e0dbc 704 Gene3D G3DSA:1.10.8.60 616 700 5.1E-22 T 28-03-2018 CDW54_RS08605 0a9931b1887ad25a80f3cbc0d29e0dbc 704 Pfam PF07724 AAA domain (Cdc48 subfamily) 448 606 1.1E-42 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CDW54_RS08605 0a9931b1887ad25a80f3cbc0d29e0dbc 704 SMART SM00382 117 264 1.2E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS08605 0a9931b1887ad25a80f3cbc0d29e0dbc 704 SMART SM00382 448 615 7.1E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS03100 9bc2eccaf8cde5c6b49f1f5311af391e 156 Pfam PF03830 PTS system sorbose subfamily IIB component 2 149 7.2E-50 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 CDW54_RS03100 9bc2eccaf8cde5c6b49f1f5311af391e 156 SUPERFAMILY SSF52728 1 155 6.02E-49 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 CDW54_RS03100 9bc2eccaf8cde5c6b49f1f5311af391e 156 Gene3D G3DSA:3.40.35.10 1 156 7.6E-52 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 CDW54_RS05925 dbd3d441e5849a5e23faf92de40a3b0a 207 Pfam PF00573 Ribosomal protein L4/L1 family 17 204 1.3E-68 T 28-03-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 CDW54_RS05925 dbd3d441e5849a5e23faf92de40a3b0a 207 SUPERFAMILY SSF52166 1 206 1.31E-79 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CDW54_RS05925 dbd3d441e5849a5e23faf92de40a3b0a 207 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 17 204 7.5E-80 T 28-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS05925 dbd3d441e5849a5e23faf92de40a3b0a 207 Gene3D G3DSA:3.40.1370.10 144 205 1.2E-10 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CDW54_RS05925 dbd3d441e5849a5e23faf92de40a3b0a 207 Gene3D G3DSA:3.40.1370.10 2 143 1.8E-58 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CDW54_RS05925 dbd3d441e5849a5e23faf92de40a3b0a 207 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 9 207 36.332 T 28-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS02645 cc4e041de967919c4b98002f5a889054 124 Gene3D G3DSA:2.60.300.12 1 115 4.6E-36 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CDW54_RS02645 cc4e041de967919c4b98002f5a889054 124 SUPERFAMILY SSF89360 1 114 3.14E-35 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CDW54_RS02645 cc4e041de967919c4b98002f5a889054 124 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 113 1.0E-33 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CDW54_RS10670 13f303a22c06d0a7a9b020a423de2654 49 Pfam PF00471 Ribosomal protein L33 3 49 1.0E-21 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS10670 13f303a22c06d0a7a9b020a423de2654 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 49 1.4E-20 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS10670 13f303a22c06d0a7a9b020a423de2654 49 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 28-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS10670 13f303a22c06d0a7a9b020a423de2654 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 18.535 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS10670 13f303a22c06d0a7a9b020a423de2654 49 SUPERFAMILY SSF57829 1 49 3.11E-18 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CDW54_RS07160 6784d9f996dbb649e9560f569e9f6713 475 Gene3D G3DSA:1.10.10.10 4 70 7.9E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS07160 6784d9f996dbb649e9560f569e9f6713 475 Pfam PF08280 M protein trans-acting positive regulator (MGA) HTH domain 7 57 1.3E-5 T 28-03-2018 IPR013199 M protein trans-acting positive regulator (MGA) HTH domain CDW54_RS03535 69f7dda0f52c568543597a81ef5b9d6f 474 Pfam PF02610 L-arabinose isomerase 6 357 4.4E-171 T 28-03-2018 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 CDW54_RS03535 69f7dda0f52c568543597a81ef5b9d6f 474 Pfam PF11762 L-arabinose isomerase C-terminal domain 360 473 1.2E-44 T 28-03-2018 IPR024664 L-arabinose isomerase, C-terminal KEGG: 00040+5.3.1.4 CDW54_RS03535 69f7dda0f52c568543597a81ef5b9d6f 474 SUPERFAMILY SSF50443 327 474 4.18E-57 T 28-03-2018 IPR004216 L-fucose/L-arabinose isomerase, C-terminal CDW54_RS03535 69f7dda0f52c568543597a81ef5b9d6f 474 ProDom PD018364 ISOMERASE L-ARABINOSE ARABINOSE METABOLISM CARBOHYDRATE CATABOLISM ARAA 6 303 1.0E-174 T 28-03-2018 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 CDW54_RS03535 69f7dda0f52c568543597a81ef5b9d6f 474 PIRSF PIRSF001478 1 474 2.1E-239 T 28-03-2018 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 CDW54_RS03535 69f7dda0f52c568543597a81ef5b9d6f 474 Hamap MF_00519 L-arabinose isomerase [araA]. 1 474 61.16 T 28-03-2018 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 CDW54_RS03535 69f7dda0f52c568543597a81ef5b9d6f 474 SUPERFAMILY SSF53743 1 326 4.45E-124 T 28-03-2018 IPR009015 L-fucose isomerase, N-terminal/central domain GO:0005737|GO:0005996|GO:0016861 CDW54_RS03595 e9b9676bcc3454f3be298b5d55c4e885 296 SMART SM00418 11 89 5.7E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CDW54_RS03595 e9b9676bcc3454f3be298b5d55c4e885 296 Gene3D G3DSA:1.10.10.10 3 99 9.2E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS03595 e9b9676bcc3454f3be298b5d55c4e885 296 Pfam PF01022 Bacterial regulatory protein, arsR family 19 63 7.3E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CDW54_RS03595 e9b9676bcc3454f3be298b5d55c4e885 296 PIRSF PIRSF030050 1 296 1.1E-141 T 28-03-2018 IPR016943 Uncharacterised conserved protein UCP030050, HTH transcriptional regulator, BH1869 CDW54_RS03595 e9b9676bcc3454f3be298b5d55c4e885 296 SUPERFAMILY SSF46785 6 206 3.4E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS00360 2c9bf9c59110d74a3a73b5556afcafcc 338 Gene3D G3DSA:3.40.50.2300 150 305 6.1E-19 T 28-03-2018 CDW54_RS00360 2c9bf9c59110d74a3a73b5556afcafcc 338 SUPERFAMILY SSF53822 30 330 6.09E-50 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CDW54_RS00360 2c9bf9c59110d74a3a73b5556afcafcc 338 Gene3D G3DSA:3.40.50.2300 29 149 2.1E-17 T 28-03-2018 CDW54_RS00360 2c9bf9c59110d74a3a73b5556afcafcc 338 Pfam PF13407 Periplasmic binding protein domain 33 304 8.9E-34 T 28-03-2018 IPR025997 Periplasmic binding protein CDW54_RS10990 c52f78786d19ea37a02f364def8f0f78 609 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 604 36.793 T 28-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 CDW54_RS10990 c52f78786d19ea37a02f364def8f0f78 609 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 574 8.1E-286 T 28-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 CDW54_RS10990 c52f78786d19ea37a02f364def8f0f78 609 SUPERFAMILY SSF53067 1 158 4.05E-57 T 28-03-2018 CDW54_RS10990 c52f78786d19ea37a02f364def8f0f78 609 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 167 180 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CDW54_RS10990 c52f78786d19ea37a02f364def8f0f78 609 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 308 322 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CDW54_RS10990 c52f78786d19ea37a02f364def8f0f78 609 Gene3D G3DSA:2.60.34.10 361 502 4.5E-66 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CDW54_RS10990 c52f78786d19ea37a02f364def8f0f78 609 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CDW54_RS10990 c52f78786d19ea37a02f364def8f0f78 609 Gene3D G3DSA:1.20.1270.10 503 588 2.9E-19 T 28-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain CDW54_RS10990 c52f78786d19ea37a02f364def8f0f78 609 PRINTS PR00301 70kDa heat shock protein signature 31 43 1.7E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDW54_RS10990 c52f78786d19ea37a02f364def8f0f78 609 PRINTS PR00301 70kDa heat shock protein signature 53 61 1.7E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDW54_RS10990 c52f78786d19ea37a02f364def8f0f78 609 PRINTS PR00301 70kDa heat shock protein signature 359 378 1.7E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDW54_RS10990 c52f78786d19ea37a02f364def8f0f78 609 PRINTS PR00301 70kDa heat shock protein signature 336 356 1.7E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDW54_RS10990 c52f78786d19ea37a02f364def8f0f78 609 PRINTS PR00301 70kDa heat shock protein signature 3 16 1.7E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDW54_RS10990 c52f78786d19ea37a02f364def8f0f78 609 PRINTS PR00301 70kDa heat shock protein signature 113 133 1.7E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDW54_RS10990 c52f78786d19ea37a02f364def8f0f78 609 PRINTS PR00301 70kDa heat shock protein signature 305 321 1.7E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDW54_RS10990 c52f78786d19ea37a02f364def8f0f78 609 PRINTS PR00301 70kDa heat shock protein signature 173 183 1.7E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDW54_RS10990 c52f78786d19ea37a02f364def8f0f78 609 PRINTS PR00301 70kDa heat shock protein signature 440 456 1.7E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDW54_RS10990 c52f78786d19ea37a02f364def8f0f78 609 SUPERFAMILY SSF100934 478 579 1.83E-12 T 28-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain CDW54_RS10990 c52f78786d19ea37a02f364def8f0f78 609 SUPERFAMILY SSF53067 162 352 1.36E-66 T 28-03-2018 CDW54_RS10990 c52f78786d19ea37a02f364def8f0f78 609 Pfam PF00012 Hsp70 protein 75 574 2.3E-220 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDW54_RS10990 c52f78786d19ea37a02f364def8f0f78 609 Pfam PF00012 Hsp70 protein 4 73 9.6E-27 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDW54_RS10990 c52f78786d19ea37a02f364def8f0f78 609 Gene3D G3DSA:3.30.420.40 172 332 6.3E-48 T 28-03-2018 CDW54_RS10990 c52f78786d19ea37a02f364def8f0f78 609 Gene3D G3DSA:3.30.420.40 1 171 7.1E-67 T 28-03-2018 CDW54_RS10990 c52f78786d19ea37a02f364def8f0f78 609 SUPERFAMILY SSF100920 355 511 1.7E-61 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CDW54_RS08415 5bdb858dbdb0f2300bbeff8d860b917c 51 Pfam PF10055 Uncharacterized small protein (DUF2292) 27 50 1.8E-5 T 28-03-2018 IPR018743 Protein of unknown function DUF2292 CDW54_RS05105 ed089ea23f40754bd120f9a9d734d4e8 456 SUPERFAMILY SSF54211 254 268 1.29E-38 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CDW54_RS05105 ed089ea23f40754bd120f9a9d734d4e8 456 SUPERFAMILY SSF54211 302 455 1.29E-38 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CDW54_RS05105 ed089ea23f40754bd120f9a9d734d4e8 456 Pfam PF13481 AAA domain 70 221 5.4E-17 T 28-03-2018 CDW54_RS05105 ed089ea23f40754bd120f9a9d734d4e8 456 Gene3D G3DSA:3.30.230.10 287 456 1.8E-28 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CDW54_RS05105 ed089ea23f40754bd120f9a9d734d4e8 456 SMART SM00382 89 243 1.5E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS05105 ed089ea23f40754bd120f9a9d734d4e8 456 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 450 2.2E-197 T 28-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 CDW54_RS05105 ed089ea23f40754bd120f9a9d734d4e8 456 SUPERFAMILY SSF52540 67 290 8.15E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS05105 ed089ea23f40754bd120f9a9d734d4e8 456 PRINTS PR01874 DNA repair protein radA signature 11 35 1.9E-88 T 28-03-2018 CDW54_RS05105 ed089ea23f40754bd120f9a9d734d4e8 456 PRINTS PR01874 DNA repair protein radA signature 247 273 1.9E-88 T 28-03-2018 CDW54_RS05105 ed089ea23f40754bd120f9a9d734d4e8 456 PRINTS PR01874 DNA repair protein radA signature 81 109 1.9E-88 T 28-03-2018 CDW54_RS05105 ed089ea23f40754bd120f9a9d734d4e8 456 PRINTS PR01874 DNA repair protein radA signature 212 240 1.9E-88 T 28-03-2018 CDW54_RS05105 ed089ea23f40754bd120f9a9d734d4e8 456 PRINTS PR01874 DNA repair protein radA signature 321 344 1.9E-88 T 28-03-2018 CDW54_RS05105 ed089ea23f40754bd120f9a9d734d4e8 456 PRINTS PR01874 DNA repair protein radA signature 173 197 1.9E-88 T 28-03-2018 CDW54_RS05105 ed089ea23f40754bd120f9a9d734d4e8 456 PRINTS PR01874 DNA repair protein radA signature 123 140 1.9E-88 T 28-03-2018 CDW54_RS05105 ed089ea23f40754bd120f9a9d734d4e8 456 Gene3D G3DSA:3.40.50.300 70 283 3.4E-48 T 28-03-2018 CDW54_RS05105 ed089ea23f40754bd120f9a9d734d4e8 456 Hamap MF_01498 DNA repair protein RadA [radA]. 22 455 44.227 T 28-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 CDW54_RS05105 ed089ea23f40754bd120f9a9d734d4e8 456 Pfam PF13541 Subunit ChlI of Mg-chelatase 362 429 2.9E-9 T 28-03-2018 CDW54_RS03105 23098b90d803679d42d0e6169729c23d 139 Gene3D G3DSA:3.40.50.510 2 139 1.3E-32 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CDW54_RS03105 23098b90d803679d42d0e6169729c23d 139 Pfam PF03610 PTS system fructose IIA component 5 102 7.6E-18 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CDW54_RS03105 23098b90d803679d42d0e6169729c23d 139 SUPERFAMILY SSF53062 3 131 8.76E-32 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CDW54_RS01735 39913cc41c68a2b4f679eadd7d1f3b7c 315 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 35 305 1.3E-11 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CDW54_RS01735 39913cc41c68a2b4f679eadd7d1f3b7c 315 SUPERFAMILY SSF51735 96 278 5.1E-50 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS01735 39913cc41c68a2b4f679eadd7d1f3b7c 315 SUPERFAMILY SSF52283 6 106 1.47E-17 T 28-03-2018 CDW54_RS01735 39913cc41c68a2b4f679eadd7d1f3b7c 315 Gene3D G3DSA:3.40.50.720 3 107 4.4E-17 T 28-03-2018 CDW54_RS01735 39913cc41c68a2b4f679eadd7d1f3b7c 315 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 103 277 3.3E-53 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CDW54_RS01735 39913cc41c68a2b4f679eadd7d1f3b7c 315 Gene3D G3DSA:3.40.50.720 108 280 3.9E-50 T 28-03-2018 CDW54_RS12445 e3f48f10d6045e9ef164066ad89b6cf3 198 Pfam PF12822 ECF transporter, substrate-specific component 9 185 5.6E-29 T 28-03-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 CDW54_RS05745 f694b7cd999ae70480f39a3337decce2 540 Pfam PF12848 ABC transporter 224 302 7.0E-22 T 28-03-2018 IPR032781 ABC-transporter extension domain CDW54_RS05745 f694b7cd999ae70480f39a3337decce2 540 SUPERFAMILY SSF52540 296 516 5.82E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS05745 f694b7cd999ae70480f39a3337decce2 540 Gene3D G3DSA:3.40.50.300 1 283 4.9E-57 T 28-03-2018 CDW54_RS05745 f694b7cd999ae70480f39a3337decce2 540 SUPERFAMILY SSF52540 7 237 4.72E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS05745 f694b7cd999ae70480f39a3337decce2 540 Pfam PF00005 ABC transporter 18 184 4.9E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS05745 f694b7cd999ae70480f39a3337decce2 540 Pfam PF00005 ABC transporter 335 468 1.3E-13 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS05745 f694b7cd999ae70480f39a3337decce2 540 Gene3D G3DSA:3.40.50.300 284 538 3.6E-39 T 28-03-2018 CDW54_RS05745 f694b7cd999ae70480f39a3337decce2 540 SMART SM00382 26 228 1.6E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS05745 f694b7cd999ae70480f39a3337decce2 540 SMART SM00382 344 519 7.9 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS01905 60129389af8779141378f9e473b26865 307 Pfam PF03631 Virulence factor BrkB 27 277 7.5E-57 T 28-03-2018 IPR017039 Virulence factor BrkB CDW54_RS01905 60129389af8779141378f9e473b26865 307 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 16 278 3.8E-33 T 28-03-2018 IPR017039 Virulence factor BrkB CDW54_RS01905 60129389af8779141378f9e473b26865 307 PIRSF PIRSF035875 1 296 1.8E-71 T 28-03-2018 IPR017039 Virulence factor BrkB CDW54_RS03815 c8701ce8dce789abffff33619bfdebd2 400 Pfam PF07690 Major Facilitator Superfamily 23 355 3.9E-26 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDW54_RS03815 c8701ce8dce789abffff33619bfdebd2 400 SUPERFAMILY SSF103473 8 396 3.01E-48 T 28-03-2018 IPR020846 Major facilitator superfamily domain CDW54_RS03815 c8701ce8dce789abffff33619bfdebd2 400 Gene3D G3DSA:1.20.1250.20 2 207 1.4E-18 T 28-03-2018 CDW54_RS03815 c8701ce8dce789abffff33619bfdebd2 400 Gene3D G3DSA:1.20.1250.20 208 400 1.4E-16 T 28-03-2018 CDW54_RS09140 4db4982154e0c54c94e95eed31996e0b 215 SUPERFAMILY SSF51735 1 198 2.63E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS09140 4db4982154e0c54c94e95eed31996e0b 215 Pfam PF13460 NAD(P)H-binding 7 187 7.1E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS09140 4db4982154e0c54c94e95eed31996e0b 215 Gene3D G3DSA:3.40.50.720 1 213 2.4E-27 T 28-03-2018 CDW54_RS04070 a1edb574e4e12943c6dde9eb5d149e80 148 SUPERFAMILY SSF69500 1 145 1.44E-58 T 28-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain CDW54_RS04070 a1edb574e4e12943c6dde9eb5d149e80 148 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 146 1.5E-59 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CDW54_RS04070 a1edb574e4e12943c6dde9eb5d149e80 148 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 144 4.5E-58 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CDW54_RS04070 a1edb574e4e12943c6dde9eb5d149e80 148 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 145 36.463 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CDW54_RS04070 a1edb574e4e12943c6dde9eb5d149e80 148 Gene3D G3DSA:3.50.80.10 1 145 4.6E-60 T 28-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain CDW54_RS12665 5e5527c58eca795f1116ab6bd266cf8a 253 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 72 245 1.1E-53 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CDW54_RS12665 5e5527c58eca795f1116ab6bd266cf8a 253 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 106 123 - T 28-03-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 CDW54_RS12665 5e5527c58eca795f1116ab6bd266cf8a 253 SUPERFAMILY SSF50891 69 248 1.9E-60 T 28-03-2018 IPR029000 Cyclophilin-like domain CDW54_RS12665 5e5527c58eca795f1116ab6bd266cf8a 253 Gene3D G3DSA:2.40.100.10 51 253 1.8E-69 T 28-03-2018 IPR029000 Cyclophilin-like domain CDW54_RS12665 5e5527c58eca795f1116ab6bd266cf8a 253 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 85 100 1.4E-15 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CDW54_RS12665 5e5527c58eca795f1116ab6bd266cf8a 253 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 206 221 1.4E-15 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CDW54_RS12665 5e5527c58eca795f1116ab6bd266cf8a 253 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 111 123 1.4E-15 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CDW54_RS06360 bae68c6d3da50e9de691976022396c2e 137 PIRSF PIRSF021287 13 134 1.8E-31 T 28-03-2018 IPR016783 Biofilm formation YmcA CDW54_RS06360 bae68c6d3da50e9de691976022396c2e 137 SUPERFAMILY SSF158622 19 128 1.24E-21 T 28-03-2018 IPR023378 YheA/YmcA-like domain CDW54_RS06360 bae68c6d3da50e9de691976022396c2e 137 Gene3D G3DSA:1.20.1500.10 19 127 8.9E-18 T 28-03-2018 IPR023378 YheA/YmcA-like domain CDW54_RS06360 bae68c6d3da50e9de691976022396c2e 137 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 20 125 3.2E-14 T 28-03-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA CDW54_RS09585 334d2a607a04c21de2ebd4cba3bf4d40 379 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 66 75 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CDW54_RS09585 334d2a607a04c21de2ebd4cba3bf4d40 379 Pfam PF07687 Peptidase dimerisation domain 173 281 7.8E-22 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CDW54_RS09585 334d2a607a04c21de2ebd4cba3bf4d40 379 SUPERFAMILY SSF53187 3 175 2.54E-58 T 28-03-2018 CDW54_RS09585 334d2a607a04c21de2ebd4cba3bf4d40 379 SUPERFAMILY SSF53187 297 377 2.54E-58 T 28-03-2018 CDW54_RS09585 334d2a607a04c21de2ebd4cba3bf4d40 379 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 102 141 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CDW54_RS09585 334d2a607a04c21de2ebd4cba3bf4d40 379 SUPERFAMILY SSF55031 176 287 2.49E-22 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CDW54_RS09585 334d2a607a04c21de2ebd4cba3bf4d40 379 Gene3D G3DSA:3.40.630.10 2 280 4.9E-71 T 28-03-2018 CDW54_RS09585 334d2a607a04c21de2ebd4cba3bf4d40 379 Pfam PF01546 Peptidase family M20/M25/M40 68 374 5.4E-36 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CDW54_RS09585 334d2a607a04c21de2ebd4cba3bf4d40 379 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 7 367 5.6E-98 T 28-03-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase CDW54_RS01225 4a7177b1afcbff3463e17eafffaba76c 411 SUPERFAMILY SSF53756 3 405 1.81E-33 T 28-03-2018 CDW54_RS01225 4a7177b1afcbff3463e17eafffaba76c 411 Gene3D G3DSA:3.40.50.2000 4 250 2.4E-18 T 28-03-2018 CDW54_RS01225 4a7177b1afcbff3463e17eafffaba76c 411 Gene3D G3DSA:3.40.50.2000 251 390 1.3E-12 T 28-03-2018 CDW54_RS04770 e86941874f8b78e5b9189b04128cd9f7 498 Pfam PF00152 tRNA synthetases class II (D, K and N) 161 497 2.6E-84 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDW54_RS04770 e86941874f8b78e5b9189b04128cd9f7 498 PRINTS PR00982 Lysyl-tRNA synthetase signature 241 254 4.9E-40 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CDW54_RS04770 e86941874f8b78e5b9189b04128cd9f7 498 PRINTS PR00982 Lysyl-tRNA synthetase signature 382 398 4.9E-40 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CDW54_RS04770 e86941874f8b78e5b9189b04128cd9f7 498 PRINTS PR00982 Lysyl-tRNA synthetase signature 212 228 4.9E-40 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CDW54_RS04770 e86941874f8b78e5b9189b04128cd9f7 498 PRINTS PR00982 Lysyl-tRNA synthetase signature 259 276 4.9E-40 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CDW54_RS04770 e86941874f8b78e5b9189b04128cd9f7 498 PRINTS PR00982 Lysyl-tRNA synthetase signature 196 206 4.9E-40 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CDW54_RS04770 e86941874f8b78e5b9189b04128cd9f7 498 Pfam PF01336 OB-fold nucleic acid binding domain 67 143 4.4E-15 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CDW54_RS04770 e86941874f8b78e5b9189b04128cd9f7 498 PIRSF PIRSF039101 1 498 4.1E-197 T 28-03-2018 IPR034762 Bacterial/eukaryotic lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CDW54_RS04770 e86941874f8b78e5b9189b04128cd9f7 498 SUPERFAMILY SSF55681 159 497 1.47E-124 T 28-03-2018 CDW54_RS04770 e86941874f8b78e5b9189b04128cd9f7 498 Gene3D G3DSA:3.30.930.10 153 497 3.0E-109 T 28-03-2018 CDW54_RS04770 e86941874f8b78e5b9189b04128cd9f7 498 SUPERFAMILY SSF50249 11 152 9.3E-45 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDW54_RS04770 e86941874f8b78e5b9189b04128cd9f7 498 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 18 498 45.023 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CDW54_RS04770 e86941874f8b78e5b9189b04128cd9f7 498 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 11 498 1.1E-216 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CDW54_RS04770 e86941874f8b78e5b9189b04128cd9f7 498 Gene3D G3DSA:2.40.50.140 12 152 1.9E-41 T 28-03-2018 CDW54_RS04795 fc3d4f8ff24720a0030a01c48f90e3bf 481 SUPERFAMILY SSF52402 24 240 2.92E-57 T 28-03-2018 CDW54_RS04795 fc3d4f8ff24720a0030a01c48f90e3bf 481 SMART SM00977 396 470 1.5E-7 T 28-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CDW54_RS04795 fc3d4f8ff24720a0030a01c48f90e3bf 481 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 13 324 23.498 T 28-03-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CDW54_RS04795 fc3d4f8ff24720a0030a01c48f90e3bf 481 Pfam PF01171 PP-loop family 33 210 1.3E-57 T 28-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 CDW54_RS04795 fc3d4f8ff24720a0030a01c48f90e3bf 481 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 397 440 1.1E-8 T 28-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CDW54_RS04795 fc3d4f8ff24720a0030a01c48f90e3bf 481 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 32 214 8.0E-60 T 28-03-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CDW54_RS04795 fc3d4f8ff24720a0030a01c48f90e3bf 481 Gene3D G3DSA:3.40.50.620 29 272 3.9E-42 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDW54_RS04795 fc3d4f8ff24720a0030a01c48f90e3bf 481 SUPERFAMILY SSF56037 389 444 1.54E-5 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CDW54_RS03800 a2e866cb4aafcf9e4f41eb8d37439b6a 237 PRINTS PR01837 MgtC/SapB protein signature 37 55 5.7E-43 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CDW54_RS03800 a2e866cb4aafcf9e4f41eb8d37439b6a 237 PRINTS PR01837 MgtC/SapB protein signature 106 130 5.7E-43 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CDW54_RS03800 a2e866cb4aafcf9e4f41eb8d37439b6a 237 PRINTS PR01837 MgtC/SapB protein signature 18 37 5.7E-43 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CDW54_RS03800 a2e866cb4aafcf9e4f41eb8d37439b6a 237 PRINTS PR01837 MgtC/SapB protein signature 79 101 5.7E-43 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CDW54_RS03800 a2e866cb4aafcf9e4f41eb8d37439b6a 237 Pfam PF02308 MgtC family 15 150 9.0E-38 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CDW54_RS03945 af97ab482c65217784a07e835e99d134 213 SUPERFAMILY SSF110395 1 209 1.31E-62 T 28-03-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 CDW54_RS03945 af97ab482c65217784a07e835e99d134 213 Gene3D G3DSA:3.20.20.380 1 212 3.2E-76 T 28-03-2018 CDW54_RS03945 af97ab482c65217784a07e835e99d134 213 Pfam PF03932 CutC family 1 208 1.9E-72 T 28-03-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 CDW54_RS08845 09b97a47c65b45848dafcee3f7cce104 288 Gene3D G3DSA:1.10.3100.10 1 111 6.4E-9 T 28-03-2018 IPR027910 YdiL-like domain CDW54_RS08845 09b97a47c65b45848dafcee3f7cce104 288 TIGRFAM TIGR01716 RGG_Cterm: transcriptional activator, Rgg/GadR/MutR family, C-terminal domain 122 280 2.5E-12 T 28-03-2018 IPR010057 Transcription activator MutR, C-terminal CDW54_RS08845 09b97a47c65b45848dafcee3f7cce104 288 SMART SM00530 6 61 6.9E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDW54_RS08845 09b97a47c65b45848dafcee3f7cce104 288 SUPERFAMILY SSF47413 3 61 1.32E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDW54_RS07080 0f802fe235ad05b8b1a58a32969474d3 438 PIRSF PIRSF006351 6 437 2.0E-133 T 28-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 CDW54_RS07080 0f802fe235ad05b8b1a58a32969474d3 438 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 19 434 1.5E-108 T 28-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 CDW54_RS07080 0f802fe235ad05b8b1a58a32969474d3 438 Pfam PF02378 Phosphotransferase system, EIIC 34 365 2.8E-46 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CDW54_RS00320 f3c010abf3dec4554d1e4393663da86a 369 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 23 361 3.3E-142 T 28-03-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 CDW54_RS00320 f3c010abf3dec4554d1e4393663da86a 369 Pfam PF00676 Dehydrogenase E1 component 52 341 6.2E-94 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CDW54_RS00320 f3c010abf3dec4554d1e4393663da86a 369 Gene3D G3DSA:3.40.50.970 37 337 6.0E-83 T 28-03-2018 CDW54_RS00320 f3c010abf3dec4554d1e4393663da86a 369 SUPERFAMILY SSF52518 22 365 3.25E-101 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CDW54_RS11730 94fa304f0c7768e056ff4e2a32e426c6 81 SUPERFAMILY SSF47413 9 75 1.27E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDW54_RS11730 94fa304f0c7768e056ff4e2a32e426c6 81 Gene3D G3DSA:1.10.260.40 2 78 1.2E-11 T 28-03-2018 CDW54_RS05995 76cdff90459d84f46973e40c74897636 178 PIRSF PIRSF002162 1 177 1.5E-49 T 28-03-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS05995 76cdff90459d84f46973e40c74897636 178 Pfam PF00347 Ribosomal protein L6 11 82 3.0E-20 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS05995 76cdff90459d84f46973e40c74897636 178 Pfam PF00347 Ribosomal protein L6 90 164 2.1E-20 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS05995 76cdff90459d84f46973e40c74897636 178 PRINTS PR00059 Ribosomal protein L6 signature 71 96 1.1E-33 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CDW54_RS05995 76cdff90459d84f46973e40c74897636 178 PRINTS PR00059 Ribosomal protein L6 signature 99 115 1.1E-33 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CDW54_RS05995 76cdff90459d84f46973e40c74897636 178 PRINTS PR00059 Ribosomal protein L6 signature 141 162 1.1E-33 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CDW54_RS05995 76cdff90459d84f46973e40c74897636 178 SUPERFAMILY SSF56053 83 177 9.95E-37 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS05995 76cdff90459d84f46973e40c74897636 178 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 28-03-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS05995 76cdff90459d84f46973e40c74897636 178 SUPERFAMILY SSF56053 2 82 2.47E-26 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS05995 76cdff90459d84f46973e40c74897636 178 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 1.5E-76 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CDW54_RS05995 76cdff90459d84f46973e40c74897636 178 Gene3D G3DSA:3.90.930.12 83 178 1.1E-40 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS05995 76cdff90459d84f46973e40c74897636 178 Gene3D G3DSA:3.90.930.12 2 82 2.3E-29 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS05995 76cdff90459d84f46973e40c74897636 178 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 38.303 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CDW54_RS05315 8a13f66525f31161c57032243b9dfb35 278 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 265 2.7E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS05315 8a13f66525f31161c57032243b9dfb35 278 SUPERFAMILY SSF161098 2 278 9.03E-70 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS05315 8a13f66525f31161c57032243b9dfb35 278 Gene3D G3DSA:1.10.3720.10 8 269 7.7E-45 T 28-03-2018 CDW54_RS03775 1f0ddb481b9ada1d4b8cd4a5fdbb447c 157 SUPERFAMILY SSF50037 4 71 8.93E-8 T 28-03-2018 IPR008988 Transcriptional repressor, C-terminal CDW54_RS03775 1f0ddb481b9ada1d4b8cd4a5fdbb447c 157 SUPERFAMILY SSF50037 84 153 4.81E-20 T 28-03-2018 IPR008988 Transcriptional repressor, C-terminal CDW54_RS03775 1f0ddb481b9ada1d4b8cd4a5fdbb447c 157 Gene3D G3DSA:2.30.30.90 2 82 4.6E-11 T 28-03-2018 CDW54_RS03775 1f0ddb481b9ada1d4b8cd4a5fdbb447c 157 SMART SM00899 2 72 2.2E-6 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CDW54_RS03775 1f0ddb481b9ada1d4b8cd4a5fdbb447c 157 SMART SM00899 81 153 4.0E-20 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CDW54_RS03775 1f0ddb481b9ada1d4b8cd4a5fdbb447c 157 Gene3D G3DSA:2.30.30.90 84 157 7.9E-20 T 28-03-2018 CDW54_RS03775 1f0ddb481b9ada1d4b8cd4a5fdbb447c 157 Pfam PF04023 FeoA domain 82 152 2.8E-15 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CDW54_RS03775 1f0ddb481b9ada1d4b8cd4a5fdbb447c 157 Pfam PF04023 FeoA domain 3 71 1.3E-8 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CDW54_RS01530 c984a86459682cb40fa79ad8874d68e4 289 Gene3D G3DSA:3.90.226.10 17 285 1.4E-74 T 28-03-2018 CDW54_RS01530 c984a86459682cb40fa79ad8874d68e4 289 Pfam PF01039 Carboxyl transferase domain 63 241 8.7E-19 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CDW54_RS01530 c984a86459682cb40fa79ad8874d68e4 289 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 12 283 1.9E-113 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CDW54_RS01530 c984a86459682cb40fa79ad8874d68e4 289 SUPERFAMILY SSF52096 30 285 2.38E-79 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CDW54_RS01530 c984a86459682cb40fa79ad8874d68e4 289 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 1 282 39.94 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CDW54_RS01530 c984a86459682cb40fa79ad8874d68e4 289 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 201 218 2.9E-37 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CDW54_RS01530 c984a86459682cb40fa79ad8874d68e4 289 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 252 261 2.9E-37 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CDW54_RS01530 c984a86459682cb40fa79ad8874d68e4 289 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 230 241 2.9E-37 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CDW54_RS01530 c984a86459682cb40fa79ad8874d68e4 289 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 130 144 2.9E-37 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CDW54_RS01530 c984a86459682cb40fa79ad8874d68e4 289 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 164 182 2.9E-37 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CDW54_RS11340 7ddd55cf08d5893777772214af4657f3 132 SUPERFAMILY SSF54913 8 105 1.97E-17 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta CDW54_RS11340 7ddd55cf08d5893777772214af4657f3 132 Gene3D G3DSA:3.30.70.120 2 110 2.7E-15 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CDW54_RS11340 7ddd55cf08d5893777772214af4657f3 132 SMART SM00938 12 107 0.0094 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CDW54_RS00420 cd8632bc9eba0fe21d3af0fad409fe21 242 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 3 217 6.0E-72 T 28-03-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 CDW54_RS00420 cd8632bc9eba0fe21d3af0fad409fe21 242 SUPERFAMILY SSF56104 2 233 5.89E-83 T 28-03-2018 CDW54_RS00420 cd8632bc9eba0fe21d3af0fad409fe21 242 ProSitePatterns PS01058 SAICAR synthetase signature 2. 173 181 - T 28-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CDW54_RS00420 cd8632bc9eba0fe21d3af0fad409fe21 242 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 4 234 32.783 T 28-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CDW54_RS00420 cd8632bc9eba0fe21d3af0fad409fe21 242 ProSitePatterns PS01057 SAICAR synthetase signature 1. 86 100 - T 28-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CDW54_RS00420 cd8632bc9eba0fe21d3af0fad409fe21 242 Gene3D G3DSA:3.30.470.20 94 220 1.5E-49 T 28-03-2018 CDW54_RS00420 cd8632bc9eba0fe21d3af0fad409fe21 242 Gene3D G3DSA:3.30.200.20 1 93 5.2E-27 T 28-03-2018 CDW54_RS00420 cd8632bc9eba0fe21d3af0fad409fe21 242 Pfam PF01259 SAICAR synthetase 7 231 1.9E-66 T 28-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CDW54_RS01100 b05a36eb85991f54fefc03f8a3f8062c 271 Gene3D G3DSA:3.40.1190.20 3 271 1.7E-50 T 28-03-2018 IPR029056 Ribokinase-like CDW54_RS01100 b05a36eb85991f54fefc03f8a3f8062c 271 Pfam PF08543 Phosphomethylpyrimidine kinase 15 263 9.3E-81 T 28-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 CDW54_RS01100 b05a36eb85991f54fefc03f8a3f8062c 271 SUPERFAMILY SSF53613 8 265 4.37E-67 T 28-03-2018 IPR029056 Ribokinase-like CDW54_RS01100 b05a36eb85991f54fefc03f8a3f8062c 271 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 8 265 6.4E-85 T 28-03-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CDW54_RS05060 8c8fdf405d14d51817d524262c834575 81 PIRSF PIRSF037257 1 81 1.2E-34 T 28-03-2018 IPR009366 Protein Veg GO:0042710 CDW54_RS05060 8c8fdf405d14d51817d524262c834575 81 Pfam PF06257 Biofilm formation stimulator VEG 4 75 4.6E-29 T 28-03-2018 IPR009366 Protein Veg GO:0042710 CDW54_RS05060 8c8fdf405d14d51817d524262c834575 81 Gene3D G3DSA:2.30.30.100 2 76 1.8E-30 T 28-03-2018 CDW54_RS02235 9ce9059dcc9add841f1845321df06aad 172 Gene3D G3DSA:2.10.109.10 34 127 8.0E-5 T 28-03-2018 CDW54_RS02235 9ce9059dcc9add841f1845321df06aad 172 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 10 132 9.6E-18 T 28-03-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 CDW54_RS02235 9ce9059dcc9add841f1845321df06aad 172 SUPERFAMILY SSF51306 30 123 3.98E-6 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CDW54_RS03910 124f59106174245cddd34f539beed8f0 359 Pfam PF07730 Histidine kinase 172 235 3.0E-14 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CDW54_RS03910 124f59106174245cddd34f539beed8f0 359 SUPERFAMILY SSF55874 237 355 4.18E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS03910 124f59106174245cddd34f539beed8f0 359 Pfam PF14501 GHKL domain 306 354 4.2E-5 T 28-03-2018 IPR032834 Sensor histidine kinase NatK, C-terminal domain CDW54_RS03910 124f59106174245cddd34f539beed8f0 359 Gene3D G3DSA:3.30.565.10 206 359 1.6E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS03125 f9656bd4ebf1adc36d8545377bfa7754 571 SMART SM00382 359 544 6.8E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS03125 f9656bd4ebf1adc36d8545377bfa7754 571 Pfam PF00664 ABC transporter transmembrane region 15 284 4.3E-44 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CDW54_RS03125 f9656bd4ebf1adc36d8545377bfa7754 571 Gene3D G3DSA:1.20.1560.10 1 315 1.3E-68 T 28-03-2018 CDW54_RS03125 f9656bd4ebf1adc36d8545377bfa7754 571 SUPERFAMILY SSF90123 4 313 5.76E-72 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CDW54_RS03125 f9656bd4ebf1adc36d8545377bfa7754 571 Pfam PF00005 ABC transporter 350 497 2.5E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS03125 f9656bd4ebf1adc36d8545377bfa7754 571 Gene3D G3DSA:3.40.50.300 317 571 4.5E-69 T 28-03-2018 CDW54_RS03125 f9656bd4ebf1adc36d8545377bfa7754 571 SUPERFAMILY SSF52540 330 568 1.08E-78 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS03125 f9656bd4ebf1adc36d8545377bfa7754 571 ProSitePatterns PS00211 ABC transporters family signature. 471 485 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS00670 94c87211bfe1af18d74b8fdc408317eb 254 Gene3D G3DSA:3.40.50.1820 21 247 2.9E-27 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CDW54_RS00670 94c87211bfe1af18d74b8fdc408317eb 254 SUPERFAMILY SSF53474 25 248 4.53E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CDW54_RS00670 94c87211bfe1af18d74b8fdc408317eb 254 Pfam PF00561 alpha/beta hydrolase fold 29 143 1.3E-11 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDW54_RS11320 163bcd9c4373677288fa9e08e3a2f10d 289 SUPERFAMILY SSF161098 50 280 1.2E-63 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS11320 163bcd9c4373677288fa9e08e3a2f10d 289 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 65 282 7.2E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS11320 163bcd9c4373677288fa9e08e3a2f10d 289 Gene3D G3DSA:1.10.3720.10 11 285 2.0E-50 T 28-03-2018 CDW54_RS10075 15520a51b36dcff3c80692f2abf1a2b5 380 Gene3D G3DSA:3.40.50.2000 131 368 9.6E-9 T 28-03-2018 CDW54_RS10075 15520a51b36dcff3c80692f2abf1a2b5 380 SUPERFAMILY SSF53756 14 266 2.67E-10 T 28-03-2018 CDW54_RS10260 28c82b2ff618a64c573d43f255db4da7 69 PRINTS PR00944 Copper ion binding protein signature 27 40 1.8E-6 T 28-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CDW54_RS10260 28c82b2ff618a64c573d43f255db4da7 69 PRINTS PR00944 Copper ion binding protein signature 53 66 1.8E-6 T 28-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CDW54_RS10260 28c82b2ff618a64c573d43f255db4da7 69 PRINTS PR00944 Copper ion binding protein signature 14 27 1.8E-6 T 28-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CDW54_RS10260 28c82b2ff618a64c573d43f255db4da7 69 PRINTS PR00944 Copper ion binding protein signature 2 14 1.8E-6 T 28-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CDW54_RS10260 28c82b2ff618a64c573d43f255db4da7 69 Gene3D G3DSA:3.30.70.100 1 69 2.8E-22 T 28-03-2018 CDW54_RS10260 28c82b2ff618a64c573d43f255db4da7 69 SUPERFAMILY SSF55008 2 68 2.49E-21 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CDW54_RS10260 28c82b2ff618a64c573d43f255db4da7 69 Pfam PF00403 Heavy-metal-associated domain 5 65 2.1E-17 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CDW54_RS10260 28c82b2ff618a64c573d43f255db4da7 69 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 2 66 4.0E-26 T 28-03-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 CDW54_RS10260 28c82b2ff618a64c573d43f255db4da7 69 ProSitePatterns PS01047 Heavy-metal-associated domain. 7 36 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CDW54_RS03750 a32704bbdab9a20e2c8a2bb319bde455 397 Gene3D G3DSA:3.40.50.300 2 275 4.5E-76 T 28-03-2018 CDW54_RS03750 a32704bbdab9a20e2c8a2bb319bde455 397 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 35 390 2.8E-146 T 28-03-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 CDW54_RS03750 a32704bbdab9a20e2c8a2bb319bde455 397 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS03750 a32704bbdab9a20e2c8a2bb319bde455 397 SMART SM00382 52 241 2.0E-21 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS03750 a32704bbdab9a20e2c8a2bb319bde455 397 SUPERFAMILY SSF54631 273 389 3.17E-16 T 28-03-2018 CDW54_RS03750 a32704bbdab9a20e2c8a2bb319bde455 397 Pfam PF00005 ABC transporter 45 191 1.9E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS03750 a32704bbdab9a20e2c8a2bb319bde455 397 SUPERFAMILY SSF52540 39 269 5.66E-76 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS03750 a32704bbdab9a20e2c8a2bb319bde455 397 Gene3D G3DSA:3.10.580.10 276 397 1.5E-11 T 28-03-2018 CDW54_RS00560 7532aa9553587fa99ce1ec7ca0999319 278 Gene3D G3DSA:1.25.40.10 212 277 0.0015 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDW54_RS00560 7532aa9553587fa99ce1ec7ca0999319 278 SMART SM00530 11 65 1.5E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDW54_RS00560 7532aa9553587fa99ce1ec7ca0999319 278 SUPERFAMILY SSF47413 7 66 4.5E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDW54_RS00560 7532aa9553587fa99ce1ec7ca0999319 278 SUPERFAMILY SSF81901 117 244 7.85E-9 T 28-03-2018 CDW54_RS00560 7532aa9553587fa99ce1ec7ca0999319 278 Pfam PF01381 Helix-turn-helix 12 63 8.1E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDW54_RS00560 7532aa9553587fa99ce1ec7ca0999319 278 Gene3D G3DSA:1.10.260.40 4 100 3.4E-15 T 28-03-2018 CDW54_RS00560 7532aa9553587fa99ce1ec7ca0999319 278 Gene3D G3DSA:1.10.150.200 167 211 8.9E-6 T 28-03-2018 CDW54_RS00560 7532aa9553587fa99ce1ec7ca0999319 278 Gene3D G3DSA:1.10.150.200 101 166 0.23 T 28-03-2018 CDW54_RS02725 111bd856720f55282ae46159a5e939de 479 Gene3D G3DSA:2.60.120.560 350 475 4.9E-24 T 28-03-2018 CDW54_RS02725 111bd856720f55282ae46159a5e939de 479 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 37 340 2.6E-86 T 28-03-2018 IPR013148 Glycosyl hydrolase family 32, N-terminal CDW54_RS02725 111bd856720f55282ae46159a5e939de 479 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 358 468 2.5E-16 T 28-03-2018 IPR013189 Glycosyl hydrolase family 32, C-terminal CDW54_RS02725 111bd856720f55282ae46159a5e939de 479 Gene3D G3DSA:2.115.10.20 2 349 9.6E-70 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CDW54_RS02725 111bd856720f55282ae46159a5e939de 479 SUPERFAMILY SSF49899 342 478 3.72E-26 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CDW54_RS02725 111bd856720f55282ae46159a5e939de 479 SMART SM00640 37 446 4.1E-115 T 28-03-2018 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 CDW54_RS02725 111bd856720f55282ae46159a5e939de 479 ProSitePatterns PS00609 Glycosyl hydrolases family 32 active site. 37 50 - T 28-03-2018 IPR018053 Glycoside hydrolase, family 32, active site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 CDW54_RS02725 111bd856720f55282ae46159a5e939de 479 TIGRFAM TIGR01322 scrB_fam: sucrose-6-phosphate hydrolase 21 456 1.6E-163 T 28-03-2018 IPR006232 Sucrose-6-phosphate hydrolase GO:0004564|GO:0005737|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 CDW54_RS02725 111bd856720f55282ae46159a5e939de 479 SUPERFAMILY SSF75005 28 341 6.75E-83 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CDW54_RS04780 89c8d35b0f5b375036418553cb4843c2 295 Gene3D G3DSA:3.55.30.10 2 234 5.4E-80 T 28-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 CDW54_RS04780 89c8d35b0f5b375036418553cb4843c2 295 Pfam PF01430 Hsp33 protein 3 279 4.5E-92 T 28-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 CDW54_RS04780 89c8d35b0f5b375036418553cb4843c2 295 PIRSF PIRSF005261 1 291 6.4E-80 T 28-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 CDW54_RS04780 89c8d35b0f5b375036418553cb4843c2 295 Hamap MF_00117 33 kDa chaperonin [hslO]. 2 291 41.016 T 28-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 CDW54_RS04780 89c8d35b0f5b375036418553cb4843c2 295 SUPERFAMILY SSF118352 231 289 4.58E-20 T 28-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 CDW54_RS04780 89c8d35b0f5b375036418553cb4843c2 295 Gene3D G3DSA:3.90.1280.10 235 288 1.4E-22 T 28-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 CDW54_RS04780 89c8d35b0f5b375036418553cb4843c2 295 SUPERFAMILY SSF64397 2 241 1.06E-77 T 28-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 CDW54_RS11980 ed6c1742839f2ef3e746c3b7ea6ea47c 282 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 219 273 9.3E-20 T 28-03-2018 IPR019264 Domain of unknown function DUF2179 CDW54_RS11980 ed6c1742839f2ef3e746c3b7ea6ea47c 282 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 11 206 1.3E-51 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT CDW54_RS11980 ed6c1742839f2ef3e746c3b7ea6ea47c 282 PIRSF PIRSF006483 1 281 4.8E-79 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT CDW54_RS01495 d3f4e7d12bbf2145aacff09f17e816e5 119 Gene3D G3DSA:3.30.460.10 3 116 1.9E-33 T 28-03-2018 CDW54_RS01495 d3f4e7d12bbf2145aacff09f17e816e5 119 Pfam PF02410 Ribosomal silencing factor during starvation 12 106 4.2E-26 T 28-03-2018 CDW54_RS01495 d3f4e7d12bbf2145aacff09f17e816e5 119 SUPERFAMILY SSF81301 4 117 8.17E-41 T 28-03-2018 CDW54_RS01495 d3f4e7d12bbf2145aacff09f17e816e5 119 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 5 107 25.179 T 28-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS CDW54_RS01495 d3f4e7d12bbf2145aacff09f17e816e5 119 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 9 106 4.9E-36 T 28-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS CDW54_RS05345 b9d635b18790fc5354c4a17114c26934 1217 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1182 0.0 T 28-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDW54_RS05345 b9d635b18790fc5354c4a17114c26934 1217 Gene3D G3DSA:2.40.50.100 911 1030 7.8E-40 T 28-03-2018 CDW54_RS05345 b9d635b18790fc5354c4a17114c26934 1217 Pfam PF04997 RNA polymerase Rpb1, domain 1 5 331 1.1E-89 T 28-03-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDW54_RS05345 b9d635b18790fc5354c4a17114c26934 1217 Pfam PF04998 RNA polymerase Rpb1, domain 5 770 1130 2.4E-64 T 28-03-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDW54_RS05345 b9d635b18790fc5354c4a17114c26934 1217 Pfam PF04983 RNA polymerase Rpb1, domain 3 478 663 9.0E-36 T 28-03-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDW54_RS05345 b9d635b18790fc5354c4a17114c26934 1217 SUPERFAMILY SSF64484 5 1182 0.0 T 28-03-2018 CDW54_RS05345 b9d635b18790fc5354c4a17114c26934 1217 Pfam PF00623 RNA polymerase Rpb1, domain 2 333 389 3.2E-9 T 28-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDW54_RS05345 b9d635b18790fc5354c4a17114c26934 1217 Pfam PF00623 RNA polymerase Rpb1, domain 2 381 474 1.0E-29 T 28-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDW54_RS05345 b9d635b18790fc5354c4a17114c26934 1217 Pfam PF05000 RNA polymerase Rpb1, domain 4 692 759 3.5E-14 T 28-03-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDW54_RS05345 b9d635b18790fc5354c4a17114c26934 1217 SMART SM00663 224 503 6.0E-184 T 28-03-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDW54_RS05345 b9d635b18790fc5354c4a17114c26934 1217 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 4 1195 18.745 T 28-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDW54_RS05345 b9d635b18790fc5354c4a17114c26934 1217 Gene3D G3DSA:2.40.40.20 335 477 2.3E-39 T 28-03-2018 CDW54_RS01975 084ca4fa6a25f97f1642fb8df26eb5bb 105 SUPERFAMILY SSF52794 4 105 1.39E-37 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CDW54_RS01975 084ca4fa6a25f97f1642fb8df26eb5bb 105 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 6 99 6.2E-24 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CDW54_RS01975 084ca4fa6a25f97f1642fb8df26eb5bb 105 Gene3D G3DSA:3.40.50.2300 5 105 3.0E-39 T 28-03-2018 CDW54_RS00175 e4c6cd340468e12ee9e47bc4d56291a5 208 SUPERFAMILY SSF56281 1 207 4.19E-49 T 28-03-2018 IPR001279 Metallo-beta-lactamase CDW54_RS00175 e4c6cd340468e12ee9e47bc4d56291a5 208 SMART SM00849 12 190 2.6E-35 T 28-03-2018 IPR001279 Metallo-beta-lactamase CDW54_RS00175 e4c6cd340468e12ee9e47bc4d56291a5 208 Pfam PF00753 Metallo-beta-lactamase superfamily 14 190 3.5E-24 T 28-03-2018 IPR001279 Metallo-beta-lactamase CDW54_RS00175 e4c6cd340468e12ee9e47bc4d56291a5 208 Gene3D G3DSA:3.60.15.10 1 208 9.0E-42 T 28-03-2018 IPR001279 Metallo-beta-lactamase CDW54_RS05785 a451c2869d9d1c7aeedc344042e94914 167 Pfam PF04892 VanZ like family 11 129 5.2E-21 T 28-03-2018 IPR006976 VanZ-like CDW54_RS11020 593e814ff2ee4c4139cf384be302c22a 421 SUPERFAMILY SSF56059 125 325 5.4E-22 T 28-03-2018 CDW54_RS11020 593e814ff2ee4c4139cf384be302c22a 421 Gene3D G3DSA:3.30.470.20 119 391 3.0E-21 T 28-03-2018 CDW54_RS03995 457d02074484b7a7e3f59f8a95385de0 132 Hamap MF_01132 Regulatory protein Spx [spxA]. 1 131 37.656 T 28-03-2018 IPR023731 Regulatory protein Spx GO:0045892 CDW54_RS03995 457d02074484b7a7e3f59f8a95385de0 132 Gene3D G3DSA:3.40.30.10 1 131 6.5E-37 T 28-03-2018 CDW54_RS03995 457d02074484b7a7e3f59f8a95385de0 132 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 2 114 4.2E-38 T 28-03-2018 IPR006504 Transcriptional regulator Spx/MgsR CDW54_RS03995 457d02074484b7a7e3f59f8a95385de0 132 Pfam PF03960 ArsC family 5 113 3.9E-23 T 28-03-2018 IPR006660 Arsenate reductase-like CDW54_RS03995 457d02074484b7a7e3f59f8a95385de0 132 SUPERFAMILY SSF52833 2 125 7.49E-39 T 28-03-2018 IPR012336 Thioredoxin-like fold CDW54_RS02260 9953ac7a3fc47b9a19cd34de42fa00f2 360 SUPERFAMILY SSF101821 70 180 5.65E-33 T 28-03-2018 CDW54_RS02260 9953ac7a3fc47b9a19cd34de42fa00f2 360 Gene3D G3DSA:2.40.30.40 69 161 8.0E-35 T 28-03-2018 IPR023367 Peptidase M42, domain 2 CDW54_RS02260 9953ac7a3fc47b9a19cd34de42fa00f2 360 SUPERFAMILY SSF53187 7 80 6.79E-67 T 28-03-2018 CDW54_RS02260 9953ac7a3fc47b9a19cd34de42fa00f2 360 SUPERFAMILY SSF53187 172 356 6.79E-67 T 28-03-2018 CDW54_RS02260 9953ac7a3fc47b9a19cd34de42fa00f2 360 Pfam PF05343 M42 glutamyl aminopeptidase 46 340 4.1E-106 T 28-03-2018 IPR008007 Peptidase M42 CDW54_RS02260 9953ac7a3fc47b9a19cd34de42fa00f2 360 PIRSF PIRSF001123 2 359 4.0E-138 T 28-03-2018 IPR008007 Peptidase M42 CDW54_RS02260 9953ac7a3fc47b9a19cd34de42fa00f2 360 Gene3D G3DSA:3.40.630.10 174 357 7.0E-44 T 28-03-2018 CDW54_RS08145 abac78b0a791e8b005cfa5809dc76d9b 341 SUPERFAMILY SSF55874 169 333 2.23E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS08145 abac78b0a791e8b005cfa5809dc76d9b 341 SMART SM00387 223 335 1.2E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS08145 abac78b0a791e8b005cfa5809dc76d9b 341 Gene3D G3DSA:3.30.565.10 147 334 3.0E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS08145 abac78b0a791e8b005cfa5809dc76d9b 341 PRINTS PR00344 Bacterial sensor protein C-terminal signature 278 288 1.9E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDW54_RS08145 abac78b0a791e8b005cfa5809dc76d9b 341 PRINTS PR00344 Bacterial sensor protein C-terminal signature 260 274 1.9E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDW54_RS08145 abac78b0a791e8b005cfa5809dc76d9b 341 PRINTS PR00344 Bacterial sensor protein C-terminal signature 319 332 1.9E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDW54_RS08145 abac78b0a791e8b005cfa5809dc76d9b 341 PRINTS PR00344 Bacterial sensor protein C-terminal signature 295 313 1.9E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDW54_RS08145 abac78b0a791e8b005cfa5809dc76d9b 341 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 224 332 4.4E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS11645 88fc8dec0a61edbe32865eb6a37e3d88 184 PIRSF PIRSF038321 1 181 1.7E-86 T 28-03-2018 IPR004699 Phosphotransferase system, enzyme II sorbitol-specific factor GO:0009401|GO:0016021 CDW54_RS11645 88fc8dec0a61edbe32865eb6a37e3d88 184 TIGRFAM TIGR00821 EII-GUT: PTS system, glucitol/sorbitol-specific, IIC component 1 179 2.8E-80 T 28-03-2018 IPR004699 Phosphotransferase system, enzyme II sorbitol-specific factor GO:0009401|GO:0016021 CDW54_RS11645 88fc8dec0a61edbe32865eb6a37e3d88 184 Pfam PF03608 PTS system enzyme II sorbitol-specific factor 4 170 2.7E-77 T 28-03-2018 IPR004699 Phosphotransferase system, enzyme II sorbitol-specific factor GO:0009401|GO:0016021 CDW54_RS04810 486b7072bee95ed3a7c974845b3a48da 89 SUPERFAMILY SSF55174 1 82 2.49E-21 T 28-03-2018 CDW54_RS04810 486b7072bee95ed3a7c974845b3a48da 89 Pfam PF01479 S4 domain 1 46 1.0E-10 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDW54_RS04810 486b7072bee95ed3a7c974845b3a48da 89 PIRSF PIRSF038881 1 89 2.2E-38 T 28-03-2018 IPR025490 RNA-binding protein, HP1423 type CDW54_RS04810 486b7072bee95ed3a7c974845b3a48da 89 SMART SM00363 1 64 7.3E-10 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDW54_RS04810 486b7072bee95ed3a7c974845b3a48da 89 Gene3D G3DSA:3.10.290.10 1 89 1.7E-16 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDW54_RS08085 eb61f7086a718cb835a31c35f645ca69 193 Gene3D G3DSA:1.10.10.60 1 48 1.2E-13 T 28-03-2018 CDW54_RS08085 eb61f7086a718cb835a31c35f645ca69 193 SUPERFAMILY SSF48498 75 185 1.13E-20 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CDW54_RS08085 eb61f7086a718cb835a31c35f645ca69 193 Gene3D G3DSA:1.10.357.10 49 186 1.7E-16 T 28-03-2018 CDW54_RS08085 eb61f7086a718cb835a31c35f645ca69 193 SUPERFAMILY SSF46689 2 66 2.92E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDW54_RS08085 eb61f7086a718cb835a31c35f645ca69 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 4.3E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDW54_RS08085 eb61f7086a718cb835a31c35f645ca69 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 4.3E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDW54_RS08085 eb61f7086a718cb835a31c35f645ca69 193 Pfam PF16925 Bacterial transcriptional repressor C-terminal 76 179 3.6E-7 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CDW54_RS08085 eb61f7086a718cb835a31c35f645ca69 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 53 2.6E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDW54_RS07495 300038f586f7acced478e0518d09283f 219 SMART SM00419 164 212 1.3E-9 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CDW54_RS07495 300038f586f7acced478e0518d09283f 219 Gene3D G3DSA:2.60.120.10 5 145 4.4E-21 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CDW54_RS07495 300038f586f7acced478e0518d09283f 219 Pfam PF13545 Crp-like helix-turn-helix domain 150 219 2.5E-16 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CDW54_RS07495 300038f586f7acced478e0518d09283f 219 Gene3D G3DSA:1.10.10.10 146 219 6.0E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS07495 300038f586f7acced478e0518d09283f 219 Pfam PF00027 Cyclic nucleotide-binding domain 33 116 6.2E-12 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CDW54_RS07495 300038f586f7acced478e0518d09283f 219 SUPERFAMILY SSF51206 11 143 3.01E-23 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like CDW54_RS07495 300038f586f7acced478e0518d09283f 219 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 170 186 3.2E-5 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CDW54_RS07495 300038f586f7acced478e0518d09283f 219 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 186 201 3.2E-5 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CDW54_RS07495 300038f586f7acced478e0518d09283f 219 SMART SM00100 13 133 4.0E-8 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CDW54_RS07495 300038f586f7acced478e0518d09283f 219 SUPERFAMILY SSF46785 147 216 6.12E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS06965 4fefed1f5bdff663f3074f816e85a342 392 Gene3D G3DSA:3.30.420.10 156 387 5.3E-5 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS06965 4fefed1f5bdff663f3074f816e85a342 392 Pfam PF00872 Transposase, Mutator family 7 368 5.1E-107 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CDW54_RS06885 4fefed1f5bdff663f3074f816e85a342 392 Gene3D G3DSA:3.30.420.10 156 387 5.3E-5 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS06885 4fefed1f5bdff663f3074f816e85a342 392 Pfam PF00872 Transposase, Mutator family 7 368 5.1E-107 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CDW54_RS03655 d1b07dab6b9c5d5134116a0d7b39f0f1 209 Pfam PF13460 NAD(P)H-binding 7 193 6.1E-16 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS03655 d1b07dab6b9c5d5134116a0d7b39f0f1 209 Gene3D G3DSA:3.40.50.720 1 209 8.1E-13 T 28-03-2018 CDW54_RS03655 d1b07dab6b9c5d5134116a0d7b39f0f1 209 SUPERFAMILY SSF51735 1 208 6.09E-25 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS05570 0e6a7f2cc731a24980c6a9d954e9608c 296 SMART SM00470 32 122 1.2E-35 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CDW54_RS05570 0e6a7f2cc731a24980c6a9d954e9608c 296 Gene3D G3DSA:1.10.10.730 123 170 3.4E-21 T 28-03-2018 CDW54_RS05570 0e6a7f2cc731a24980c6a9d954e9608c 296 SUPERFAMILY SSF110849 32 124 3.4E-28 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CDW54_RS05570 0e6a7f2cc731a24980c6a9d954e9608c 296 Pfam PF08535 KorB domain 145 179 2.4E-5 T 28-03-2018 IPR013741 Repressor KorB domain CDW54_RS05570 0e6a7f2cc731a24980c6a9d954e9608c 296 Pfam PF02195 ParB-like nuclease domain 34 121 1.8E-27 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CDW54_RS05570 0e6a7f2cc731a24980c6a9d954e9608c 296 Gene3D G3DSA:3.90.1530.10 19 122 2.0E-36 T 28-03-2018 CDW54_RS05570 0e6a7f2cc731a24980c6a9d954e9608c 296 SUPERFAMILY SSF109709 115 224 4.18E-34 T 28-03-2018 CDW54_RS05570 0e6a7f2cc731a24980c6a9d954e9608c 296 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 30 198 8.8E-59 T 28-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 CDW54_RS11310 4b963aeef1f4e5ea763ab3bf7663aa2c 502 Pfam PF12833 Helix-turn-helix domain 420 497 8.2E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CDW54_RS11310 4b963aeef1f4e5ea763ab3bf7663aa2c 502 Gene3D G3DSA:3.90.1240.10 341 464 8.5E-21 T 28-03-2018 CDW54_RS11310 4b963aeef1f4e5ea763ab3bf7663aa2c 502 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 448 492 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CDW54_RS11310 4b963aeef1f4e5ea763ab3bf7663aa2c 502 SUPERFAMILY SSF52172 2 148 1.71E-27 T 28-03-2018 IPR011006 CheY-like superfamily CDW54_RS11310 4b963aeef1f4e5ea763ab3bf7663aa2c 502 SUPERFAMILY SSF46689 449 498 2.73E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDW54_RS11310 4b963aeef1f4e5ea763ab3bf7663aa2c 502 SMART SM00342 413 496 5.3E-26 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CDW54_RS11310 4b963aeef1f4e5ea763ab3bf7663aa2c 502 Pfam PF00072 Response regulator receiver domain 5 107 1.7E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDW54_RS11310 4b963aeef1f4e5ea763ab3bf7663aa2c 502 Gene3D G3DSA:3.40.50.2300 1 235 4.1E-28 T 28-03-2018 CDW54_RS11310 4b963aeef1f4e5ea763ab3bf7663aa2c 502 Gene3D G3DSA:1.10.10.60 465 499 9.5E-14 T 28-03-2018 CDW54_RS11310 4b963aeef1f4e5ea763ab3bf7663aa2c 502 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 480 496 6.7E-7 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CDW54_RS11310 4b963aeef1f4e5ea763ab3bf7663aa2c 502 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 465 480 6.7E-7 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CDW54_RS11310 4b963aeef1f4e5ea763ab3bf7663aa2c 502 SMART SM00448 3 118 2.8E-17 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDW54_RS02310 da73b8bdc0d8b6eadca5bbba94ad8b5f 200 Gene3D G3DSA:3.80.30.10 77 197 1.2E-12 T 28-03-2018 CDW54_RS02310 da73b8bdc0d8b6eadca5bbba94ad8b5f 200 Pfam PF13353 4Fe-4S single cluster domain 28 167 5.3E-51 T 28-03-2018 CDW54_RS02310 da73b8bdc0d8b6eadca5bbba94ad8b5f 200 TIGRFAM TIGR02491 NrdG: anaerobic ribonucleoside-triphosphate reductase activating protein 19 169 4.5E-56 T 28-03-2018 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 CDW54_RS02310 da73b8bdc0d8b6eadca5bbba94ad8b5f 200 PIRSF PIRSF000368 9 184 6.9E-71 T 28-03-2018 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 CDW54_RS02310 da73b8bdc0d8b6eadca5bbba94ad8b5f 200 SUPERFAMILY SSF102114 40 110 3.34E-9 T 28-03-2018 CDW54_RS09165 b78ace71861a091f18156b04762776bc 180 SMART SM00530 6 61 1.4E-16 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDW54_RS09165 b78ace71861a091f18156b04762776bc 180 Pfam PF07883 Cupin domain 124 174 7.8E-10 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CDW54_RS09165 b78ace71861a091f18156b04762776bc 180 Gene3D G3DSA:2.60.120.10 72 179 1.7E-12 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CDW54_RS09165 b78ace71861a091f18156b04762776bc 180 Gene3D G3DSA:1.10.260.40 1 71 2.4E-20 T 28-03-2018 CDW54_RS09165 b78ace71861a091f18156b04762776bc 180 SUPERFAMILY SSF47413 1 65 6.76E-19 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDW54_RS09165 b78ace71861a091f18156b04762776bc 180 SUPERFAMILY SSF51182 54 177 5.35E-23 T 28-03-2018 IPR011051 RmlC-like cupin domain CDW54_RS09165 b78ace71861a091f18156b04762776bc 180 Pfam PF01381 Helix-turn-helix 7 61 1.3E-16 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDW54_RS09995 81d3af72b038161e70733a8ea8c1ba89 730 SUPERFAMILY SSF109604 500 655 2.68E-14 T 28-03-2018 CDW54_RS09995 81d3af72b038161e70733a8ea8c1ba89 730 TIGRFAM TIGR00277 HDIG: HDIG domain 508 607 3.4E-22 T 28-03-2018 IPR006675 HDIG domain CDW54_RS09995 81d3af72b038161e70733a8ea8c1ba89 730 Gene3D G3DSA:1.10.3210.10 477 694 4.7E-27 T 28-03-2018 CDW54_RS09995 81d3af72b038161e70733a8ea8c1ba89 730 Pfam PF01966 HD domain 511 653 8.8E-19 T 28-03-2018 IPR006674 HD domain CDW54_RS09995 81d3af72b038161e70733a8ea8c1ba89 730 Pfam PF07698 7TM receptor with intracellular HD hydrolase 289 483 3.4E-31 T 28-03-2018 IPR011621 Metal-dependent phosphohydrolase, 7TM intracellular domain CDW54_RS09995 81d3af72b038161e70733a8ea8c1ba89 730 SMART SM00471 507 663 1.1E-9 T 28-03-2018 IPR003607 HD/PDEase domain CDW54_RS09995 81d3af72b038161e70733a8ea8c1ba89 730 Pfam PF07697 7TM-HD extracellular 46 282 2.5E-38 T 28-03-2018 IPR011624 Metal-dependent phosphohydrolase, 7TM extracellular domain CDW54_RS02435 4fb641787a1224f40b42f3dc12644c3d 431 SUPERFAMILY SSF52540 94 371 3.35E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS02435 4fb641787a1224f40b42f3dc12644c3d 431 Pfam PF07498 Rho termination factor, N-terminal domain 9 51 1.5E-11 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CDW54_RS02435 4fb641787a1224f40b42f3dc12644c3d 431 SUPERFAMILY SSF68912 6 51 8.24E-9 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CDW54_RS02435 4fb641787a1224f40b42f3dc12644c3d 431 TIGRFAM TIGR00767 rho: transcription termination factor Rho 7 415 1.9E-193 T 28-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 CDW54_RS02435 4fb641787a1224f40b42f3dc12644c3d 431 SUPERFAMILY SSF50249 54 128 4.28E-23 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDW54_RS02435 4fb641787a1224f40b42f3dc12644c3d 431 Pfam PF07497 Rho termination factor, RNA-binding domain 55 128 1.4E-30 T 28-03-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 CDW54_RS02435 4fb641787a1224f40b42f3dc12644c3d 431 Gene3D G3DSA:2.40.50.140 6 122 2.8E-41 T 28-03-2018 CDW54_RS02435 4fb641787a1224f40b42f3dc12644c3d 431 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 159 363 8.3E-17 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CDW54_RS02435 4fb641787a1224f40b42f3dc12644c3d 431 Gene3D G3DSA:3.40.50.300 123 367 4.0E-47 T 28-03-2018 CDW54_RS02435 4fb641787a1224f40b42f3dc12644c3d 431 SMART SM00959 9 51 1.6E-11 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CDW54_RS02435 4fb641787a1224f40b42f3dc12644c3d 431 SMART SM00357 56 121 7.4E-14 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CDW54_RS02435 4fb641787a1224f40b42f3dc12644c3d 431 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 419 212.329 T 28-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 CDW54_RS02435 4fb641787a1224f40b42f3dc12644c3d 431 SMART SM00382 170 349 6.3E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS12290 be1e902cda5d97871872300e9ba9a816 387 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 162 305 3.6E-49 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CDW54_RS12290 be1e902cda5d97871872300e9ba9a816 387 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 161 305 6.6E-31 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CDW54_RS08290 adbdf991144aea0a8c3c91125d364b67 321 Pfam PF03595 Voltage-dependent anion channel 12 297 2.6E-21 T 28-03-2018 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 CDW54_RS00565 dc172e230c326dcbf351bcba346b0d64 405 Gene3D G3DSA:3.40.640.10 53 280 6.5E-49 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDW54_RS00565 dc172e230c326dcbf351bcba346b0d64 405 SUPERFAMILY SSF53383 7 401 2.58E-93 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDW54_RS00565 dc172e230c326dcbf351bcba346b0d64 405 Gene3D G3DSA:3.90.1150.10 281 405 3.4E-22 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDW54_RS00565 dc172e230c326dcbf351bcba346b0d64 405 Pfam PF00155 Aminotransferase class I and II 36 387 2.9E-48 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CDW54_RS02155 86e32f29ef6537de3b33908a74309daf 354 Gene3D G3DSA:3.40.350.10 1 114 2.8E-30 T 28-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CDW54_RS02155 86e32f29ef6537de3b33908a74309daf 354 SUPERFAMILY SSF53092 1 126 8.37E-30 T 28-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal CDW54_RS02155 86e32f29ef6537de3b33908a74309daf 354 Gene3D G3DSA:3.90.230.10 115 353 3.9E-84 T 28-03-2018 CDW54_RS02155 86e32f29ef6537de3b33908a74309daf 354 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 284 296 - T 28-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site CDW54_RS02155 86e32f29ef6537de3b33908a74309daf 354 Pfam PF00557 Metallopeptidase family M24 137 338 9.8E-67 T 28-03-2018 IPR000994 Peptidase M24 CDW54_RS02155 86e32f29ef6537de3b33908a74309daf 354 SUPERFAMILY SSF55920 89 349 4.97E-86 T 28-03-2018 IPR000994 Peptidase M24 CDW54_RS02155 86e32f29ef6537de3b33908a74309daf 354 Pfam PF01321 Creatinase/Prolidase N-terminal domain 4 128 2.8E-28 T 28-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 CDW54_RS00635 9fab412495376f6b013d2882dc74a32b 512 Gene3D G3DSA:3.40.190.10 224 388 6.4E-33 T 28-03-2018 CDW54_RS00635 9fab412495376f6b013d2882dc74a32b 512 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 235 503 1.6E-65 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CDW54_RS00635 9fab412495376f6b013d2882dc74a32b 512 Gene3D G3DSA:3.40.190.10 389 508 1.6E-26 T 28-03-2018 CDW54_RS00635 9fab412495376f6b013d2882dc74a32b 512 SUPERFAMILY SSF161098 13 198 1.53E-37 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS00635 9fab412495376f6b013d2882dc74a32b 512 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 37 203 7.3E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS00635 9fab412495376f6b013d2882dc74a32b 512 SUPERFAMILY SSF53850 234 507 5.19E-74 T 28-03-2018 CDW54_RS00635 9fab412495376f6b013d2882dc74a32b 512 Gene3D G3DSA:1.10.3720.10 1 210 4.9E-29 T 28-03-2018 CDW54_RS00180 eef4f5239240f1123758e601847db9e0 234 SUPERFAMILY SSF53254 1 223 7.72E-53 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CDW54_RS00180 eef4f5239240f1123758e601847db9e0 234 Gene3D G3DSA:3.40.50.1240 1 231 1.9E-45 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CDW54_RS00180 eef4f5239240f1123758e601847db9e0 234 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 219 7.2E-37 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CDW54_RS00180 eef4f5239240f1123758e601847db9e0 234 PIRSF PIRSF000709 1 96 3.6E-4 T 28-03-2018 CDW54_RS00180 eef4f5239240f1123758e601847db9e0 234 SMART SM00855 5 182 1.8E-17 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CDW54_RS00755 b025e6774c33b9b7376d869d7dd0bfc9 301 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 5 301 52.819 T 28-03-2018 IPR023009 Tyrosine recombinase XerC/XerD CDW54_RS00755 b025e6774c33b9b7376d869d7dd0bfc9 301 Pfam PF00589 Phage integrase family 114 287 9.7E-51 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CDW54_RS00755 b025e6774c33b9b7376d869d7dd0bfc9 301 Gene3D G3DSA:1.10.150.130 4 111 7.0E-21 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CDW54_RS00755 b025e6774c33b9b7376d869d7dd0bfc9 301 Gene3D G3DSA:1.10.443.10 113 295 4.8E-49 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CDW54_RS00755 b025e6774c33b9b7376d869d7dd0bfc9 301 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 8 301 4.9E-108 T 28-03-2018 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007049|GO:0007059|GO:0015074|GO:0051301 CDW54_RS00755 b025e6774c33b9b7376d869d7dd0bfc9 301 SUPERFAMILY SSF56349 4 292 1.15E-56 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CDW54_RS00755 b025e6774c33b9b7376d869d7dd0bfc9 301 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 8 91 1.3E-18 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CDW54_RS00880 3adad427309071c3f1a289fc4494cd9e 110 PIRSF PIRSF029904 2 110 3.1E-51 T 28-03-2018 IPR012359 NTP pyrophosphohydrolase MazG-related, YpjD CDW54_RS00880 3adad427309071c3f1a289fc4494cd9e 110 SUPERFAMILY SSF101386 6 105 2.13E-28 T 28-03-2018 CDW54_RS00880 3adad427309071c3f1a289fc4494cd9e 110 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 27 105 1.1E-19 T 28-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core CDW54_RS00880 3adad427309071c3f1a289fc4494cd9e 110 Gene3D G3DSA:1.10.3420.10 2 110 1.0E-29 T 28-03-2018 CDW54_RS08160 52e1bf009c0f640ce1aa67cb3daa4f21 398 PIRSF PIRSF026508 27 398 3.8E-113 T 28-03-2018 IPR008863 Toxic anion resistance CDW54_RS08160 52e1bf009c0f640ce1aa67cb3daa4f21 398 Pfam PF05816 Toxic anion resistance protein (TelA) 66 394 1.6E-124 T 28-03-2018 IPR008863 Toxic anion resistance CDW54_RS01720 727d765bf9be14e36b7be88a3034dca9 156 Pfam PF04138 GtrA-like protein 22 139 1.7E-25 T 28-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 CDW54_RS06905 fcea23357eca531126238ebece3c6dca 466 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 54 381 2.9E-73 T 28-03-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 CDW54_RS06905 fcea23357eca531126238ebece3c6dca 466 SUPERFAMILY SSF53383 8 446 5.74E-134 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDW54_RS06905 fcea23357eca531126238ebece3c6dca 466 Gene3D G3DSA:3.40.640.10 66 323 1.2E-32 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDW54_RS06905 fcea23357eca531126238ebece3c6dca 466 Gene3D G3DSA:3.90.1150.10 324 448 1.3E-29 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDW54_RS06905 fcea23357eca531126238ebece3c6dca 466 TIGRFAM TIGR01788 Glu-decarb-GAD: glutamate decarboxylase 17 446 5.0E-204 T 28-03-2018 IPR010107 Glutamate decarboxylase GO:0004351|GO:0006536|GO:0030170 KEGG: 00250+4.1.1.15|KEGG: 00410+4.1.1.15|KEGG: 00430+4.1.1.15|KEGG: 00650+4.1.1.15|MetaCyc: PWY-4321 CDW54_RS06580 0e0e9a8f370ff823ebf7b6be9fa2ad6c 116 Gene3D G3DSA:3.90.470.20 1 116 1.2E-29 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CDW54_RS06580 0e0e9a8f370ff823ebf7b6be9fa2ad6c 116 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 116 22.003 T 28-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CDW54_RS06580 0e0e9a8f370ff823ebf7b6be9fa2ad6c 116 SUPERFAMILY SSF56214 1 115 1.7E-30 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CDW54_RS06580 0e0e9a8f370ff823ebf7b6be9fa2ad6c 116 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 1 115 3.8E-26 T 28-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CDW54_RS06580 0e0e9a8f370ff823ebf7b6be9fa2ad6c 116 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 70 2.0E-31 T 28-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CDW54_RS06580 0e0e9a8f370ff823ebf7b6be9fa2ad6c 116 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 1 115 8.3E-27 T 28-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CDW54_RS06580 0e0e9a8f370ff823ebf7b6be9fa2ad6c 116 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 4 98 1.8E-18 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CDW54_RS02740 2d0a569c5ebc98845946c4463a02cb09 60 Gene3D G3DSA:3.30.420.10 5 58 4.9E-4 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS02740 2d0a569c5ebc98845946c4463a02cb09 60 Pfam PF13333 Integrase core domain 25 55 8.6E-11 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CDW54_RS00775 4e70ae8cc686d4f2b6e2b3df30029b5c 319 Pfam PF00665 Integrase core domain 167 265 1.9E-9 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CDW54_RS00775 4e70ae8cc686d4f2b6e2b3df30029b5c 319 Gene3D G3DSA:3.30.420.10 155 317 7.4E-21 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS00775 4e70ae8cc686d4f2b6e2b3df30029b5c 319 SUPERFAMILY SSF53098 160 309 1.9E-20 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS00775 4e70ae8cc686d4f2b6e2b3df30029b5c 319 Gene3D G3DSA:1.10.10.60 6 68 1.1E-4 T 28-03-2018 CDW54_RS03155 db4a65b88cc403d68e93254cf20d267f 294 Pfam PF00398 Ribosomal RNA adenine dimethylase 22 280 1.6E-71 T 28-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm CDW54_RS03155 db4a65b88cc403d68e93254cf20d267f 294 SMART SM00650 38 214 5.9E-88 T 28-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 CDW54_RS03155 db4a65b88cc403d68e93254cf20d267f 294 SUPERFAMILY SSF53335 18 291 2.62E-79 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDW54_RS03155 db4a65b88cc403d68e93254cf20d267f 294 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 54 81 - T 28-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 CDW54_RS03155 db4a65b88cc403d68e93254cf20d267f 294 Gene3D G3DSA:1.10.8.100 228 291 3.1E-26 T 28-03-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 CDW54_RS03155 db4a65b88cc403d68e93254cf20d267f 294 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 22 288 8.9E-86 T 28-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CDW54_RS03155 db4a65b88cc403d68e93254cf20d267f 294 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 22 290 56.043 T 28-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CDW54_RS03155 db4a65b88cc403d68e93254cf20d267f 294 Gene3D G3DSA:3.40.50.150 3 227 2.9E-62 T 28-03-2018 CDW54_RS07230 565ba3081df5db9a521198d0bbf1034e 197 Pfam PF10620 Phosphoribosyl-dephospho-CoA transferase MdcG 4 194 4.8E-33 T 28-03-2018 IPR017557 Phosphoribosyl-dephospho-CoA transferase GO:0016779 MetaCyc: PWY-5796 CDW54_RS07230 565ba3081df5db9a521198d0bbf1034e 197 TIGRFAM TIGR03135 malonate_mdcG: malonate decarboxylase holo-[acyl-carrier-protein] synthase 4 194 1.1E-39 T 28-03-2018 IPR017557 Phosphoribosyl-dephospho-CoA transferase GO:0016779 MetaCyc: PWY-5796 CDW54_RS00555 a77832495bf8ff5ce85b39b2465a8493 382 Gene3D G3DSA:3.20.20.140 69 350 6.7E-101 T 28-03-2018 CDW54_RS00555 a77832495bf8ff5ce85b39b2465a8493 382 PIRSF PIRSF038994 6 382 1.2E-118 T 28-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 CDW54_RS00555 a77832495bf8ff5ce85b39b2465a8493 382 SUPERFAMILY SSF51556 54 350 5.76E-97 T 28-03-2018 IPR032466 Metal-dependent hydrolase CDW54_RS00555 a77832495bf8ff5ce85b39b2465a8493 382 Gene3D G3DSA:2.30.40.10 1 68 6.2E-10 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CDW54_RS00555 a77832495bf8ff5ce85b39b2465a8493 382 Pfam PF01979 Amidohydrolase family 51 376 1.9E-17 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CDW54_RS00555 a77832495bf8ff5ce85b39b2465a8493 382 SUPERFAMILY SSF51338 350 381 2.38E-13 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CDW54_RS00555 a77832495bf8ff5ce85b39b2465a8493 382 SUPERFAMILY SSF51338 2 53 2.38E-13 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CDW54_RS00555 a77832495bf8ff5ce85b39b2465a8493 382 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 34 376 1.2E-90 T 28-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 CDW54_RS07525 d07262f4afb25efdd12cb7ab7d25d896 625 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 370 480 2.0E-5 T 28-03-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 CDW54_RS07525 d07262f4afb25efdd12cb7ab7d25d896 625 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 211 331 9.1E-12 T 28-03-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 CDW54_RS07525 d07262f4afb25efdd12cb7ab7d25d896 625 Gene3D G3DSA:3.40.640.10 104 444 4.7E-37 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDW54_RS07525 d07262f4afb25efdd12cb7ab7d25d896 625 Gene3D G3DSA:3.90.1150.10 445 611 4.4E-4 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDW54_RS07525 d07262f4afb25efdd12cb7ab7d25d896 625 ProSitePatterns PS00392 DDC / GAD / HDC / TyrDC pyridoxal-phosphate attachment site. 383 404 - T 28-03-2018 IPR021115 Pyridoxal-phosphate binding site GO:0016831 CDW54_RS07525 d07262f4afb25efdd12cb7ab7d25d896 625 SUPERFAMILY SSF53383 23 171 3.75E-77 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDW54_RS07525 d07262f4afb25efdd12cb7ab7d25d896 625 SUPERFAMILY SSF53383 576 609 3.75E-77 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDW54_RS07525 d07262f4afb25efdd12cb7ab7d25d896 625 SUPERFAMILY SSF53383 367 538 3.75E-77 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDW54_RS07525 d07262f4afb25efdd12cb7ab7d25d896 625 SUPERFAMILY SSF53383 218 334 3.75E-77 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDW54_RS07525 d07262f4afb25efdd12cb7ab7d25d896 625 TIGRFAM TIGR03811 tyr_de_CO2_Ent: tyrosine decarboxylase 8 615 0.0 T 28-03-2018 IPR022397 Tyrosine decarboxylase, bacteria CDW54_RS10730 9cd9584d88a83897ab75241bd4323302 603 Pfam PF13454 FAD-NAD(P)-binding 5 178 2.2E-40 T 28-03-2018 CDW54_RS10730 9cd9584d88a83897ab75241bd4323302 603 Gene3D G3DSA:3.50.50.60 1 572 3.8E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS10730 9cd9584d88a83897ab75241bd4323302 603 SUPERFAMILY SSF51905 1 60 4.1E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS10730 9cd9584d88a83897ab75241bd4323302 603 SUPERFAMILY SSF51905 123 233 4.1E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS05835 fb96f95b3233ba7e196adb4ea2d295e9 132 SUPERFAMILY SSF53927 6 132 5.23E-49 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CDW54_RS05835 fb96f95b3233ba7e196adb4ea2d295e9 132 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 4 100 1.7E-16 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CDW54_RS05835 fb96f95b3233ba7e196adb4ea2d295e9 132 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 9 132 3.3E-46 T 28-03-2018 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-6798695|Reactome: R-HSA-73614 CDW54_RS05835 fb96f95b3233ba7e196adb4ea2d295e9 132 Gene3D G3DSA:3.40.140.10 1 132 2.3E-51 T 28-03-2018 CDW54_RS02810 f9701b0f31c9f2fef2ad94cf170b936c 396 Pfam PF00872 Transposase, Mutator family 7 368 2.9E-102 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CDW54_RS05290 e7b7e8009240f99e1b02e6eea03c24c3 376 SUPERFAMILY SSF110738 1 368 4.45E-124 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CDW54_RS05290 e7b7e8009240f99e1b02e6eea03c24c3 376 PIRSF PIRSF006078 1 370 6.8E-117 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CDW54_RS05290 e7b7e8009240f99e1b02e6eea03c24c3 376 Gene3D G3DSA:3.90.1510.10 42 270 1.5E-71 T 28-03-2018 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 CDW54_RS05290 e7b7e8009240f99e1b02e6eea03c24c3 376 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 2 368 1.1E-131 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CDW54_RS05290 e7b7e8009240f99e1b02e6eea03c24c3 376 Pfam PF02595 Glycerate kinase family 3 366 7.3E-125 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CDW54_RS07380 70844f3c3b248d02ce901742c2361c95 486 Pfam PF05043 Mga helix-turn-helix domain 78 161 1.4E-23 T 28-03-2018 IPR007737 Mga helix-turn-helix domain CDW54_RS07380 70844f3c3b248d02ce901742c2361c95 486 Gene3D G3DSA:1.10.10.10 81 155 5.4E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS05175 68a79c19e2d04ee856851c1a6d6027bb 154 Gene3D G3DSA:1.10.10.10 2 147 5.0E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS05175 68a79c19e2d04ee856851c1a6d6027bb 154 SMART SM00347 23 123 2.1E-19 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDW54_RS05175 68a79c19e2d04ee856851c1a6d6027bb 154 Pfam PF01047 MarR family 30 88 4.1E-16 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDW54_RS05175 68a79c19e2d04ee856851c1a6d6027bb 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 113 133 5.2E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDW54_RS05175 68a79c19e2d04ee856851c1a6d6027bb 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 47 63 5.2E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDW54_RS05175 68a79c19e2d04ee856851c1a6d6027bb 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 79 5.2E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDW54_RS05175 68a79c19e2d04ee856851c1a6d6027bb 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 83 99 5.2E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDW54_RS05175 68a79c19e2d04ee856851c1a6d6027bb 154 SUPERFAMILY SSF46785 5 137 3.46E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS04090 d4cc47cc7a8608b18d9a032f6bc1f6df 315 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 3 304 6.5E-82 T 28-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CDW54_RS04090 d4cc47cc7a8608b18d9a032f6bc1f6df 315 SUPERFAMILY SSF53335 61 310 3.65E-39 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDW54_RS04090 d4cc47cc7a8608b18d9a032f6bc1f6df 315 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 3 311 35.528 T 28-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CDW54_RS04090 d4cc47cc7a8608b18d9a032f6bc1f6df 315 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 2 311 3.8E-100 T 28-03-2018 CDW54_RS04090 d4cc47cc7a8608b18d9a032f6bc1f6df 315 Gene3D G3DSA:3.40.50.150 116 315 1.3E-36 T 28-03-2018 CDW54_RS04090 d4cc47cc7a8608b18d9a032f6bc1f6df 315 PIRSF PIRSF000401 1 313 2.2E-116 T 28-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CDW54_RS01815 4a4dac31019aeb641ab6cb16ec4e49d9 233 Gene3D G3DSA:3.90.550.10 1 233 2.5E-38 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDW54_RS01815 4a4dac31019aeb641ab6cb16ec4e49d9 233 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 2 230 1.9E-42 T 28-03-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CDW54_RS01815 4a4dac31019aeb641ab6cb16ec4e49d9 233 SUPERFAMILY SSF53448 1 229 2.5E-46 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDW54_RS10925 c5cb60fadea5132da3b3371ccb054172 150 SUPERFAMILY SSF46955 4 50 2.2E-8 T 28-03-2018 IPR009061 Putative DNA-binding domain CDW54_RS10925 c5cb60fadea5132da3b3371ccb054172 150 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 4 50 6.9E-10 T 28-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 CDW54_RS10925 c5cb60fadea5132da3b3371ccb054172 150 Pfam PF12728 Helix-turn-helix domain 4 50 1.5E-10 T 28-03-2018 CDW54_RS10925 c5cb60fadea5132da3b3371ccb054172 150 Gene3D G3DSA:1.10.1660.20 1 46 1.5E-8 T 28-03-2018 CDW54_RS06460 2d8d60f2070f190f55c13d316c71cb8a 280 SMART SM01266 8 60 6.1E-18 T 28-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 CDW54_RS06460 2d8d60f2070f190f55c13d316c71cb8a 280 TIGRFAM TIGR01805 CM_mono_grmpos: chorismate mutase 194 274 4.1E-28 T 28-03-2018 IPR011279 Chorismate mutase, Gram-positive CDW54_RS06460 2d8d60f2070f190f55c13d316c71cb8a 280 Gene3D G3DSA:2.160.10.10 2 191 3.0E-52 T 28-03-2018 CDW54_RS06460 2d8d60f2070f190f55c13d316c71cb8a 280 SUPERFAMILY SSF48600 190 276 4.88E-21 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CDW54_RS06460 2d8d60f2070f190f55c13d316c71cb8a 280 SUPERFAMILY SSF51161 5 188 6.65E-50 T 28-03-2018 IPR011004 Trimeric LpxA-like CDW54_RS06460 2d8d60f2070f190f55c13d316c71cb8a 280 SMART SM00830 198 277 1.2E-25 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CDW54_RS06460 2d8d60f2070f190f55c13d316c71cb8a 280 Pfam PF01817 Chorismate mutase type II 198 275 3.7E-21 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CDW54_RS06460 2d8d60f2070f190f55c13d316c71cb8a 280 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 131 166 8.9E-10 T 28-03-2018 IPR001451 Hexapeptide repeat CDW54_RS06460 2d8d60f2070f190f55c13d316c71cb8a 280 Pfam PF12464 Maltose acetyltransferase 10 59 3.6E-12 T 28-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 CDW54_RS06460 2d8d60f2070f190f55c13d316c71cb8a 280 Gene3D G3DSA:1.20.59.10 192 280 1.8E-24 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CDW54_RS00950 11d70f20e045ca898af6624250810c55 245 SUPERFAMILY SSF53474 58 211 1.05E-18 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CDW54_RS00950 11d70f20e045ca898af6624250810c55 245 Pfam PF12695 Alpha/beta hydrolase family 66 230 4.1E-64 T 28-03-2018 IPR029059 Alpha/beta hydrolase fold-5 CDW54_RS00950 11d70f20e045ca898af6624250810c55 245 Gene3D G3DSA:3.40.50.1820 26 245 1.3E-18 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CDW54_RS07245 907e63f37f76c32c97a1cbc17477a2dd 254 SUPERFAMILY SSF54427 128 235 1.05E-7 T 28-03-2018 IPR032710 NTF2-like domain CDW54_RS07245 907e63f37f76c32c97a1cbc17477a2dd 254 Pfam PF04280 Tim44-like domain 126 243 7.8E-9 T 28-03-2018 IPR007379 Tim44-like domain CDW54_RS08305 39f64449d553b8d67062194bb6d6fbd3 395 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 344 368 - T 28-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 CDW54_RS08305 39f64449d553b8d67062194bb6d6fbd3 395 Pfam PF01098 Cell cycle protein 19 386 1.2E-81 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CDW54_RS03970 97af35c4c8e7dddf4ce4012c6c6eccc2 191 SUPERFAMILY SSF55154 4 186 7.52E-27 T 28-03-2018 IPR033469 CYTH-like domain Reactome: R-HSA-196819 CDW54_RS03970 97af35c4c8e7dddf4ce4012c6c6eccc2 191 SMART SM01118 4 190 1.1E-19 T 28-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 CDW54_RS03970 97af35c4c8e7dddf4ce4012c6c6eccc2 191 Pfam PF01928 CYTH domain 4 186 7.8E-24 T 28-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 CDW54_RS03970 97af35c4c8e7dddf4ce4012c6c6eccc2 191 PIRSF PIRSF012526 1 191 1.2E-55 T 28-03-2018 IPR009195 Uncharacterised protein family YjbK CDW54_RS03970 97af35c4c8e7dddf4ce4012c6c6eccc2 191 Gene3D G3DSA:2.40.320.10 2 191 2.9E-28 T 28-03-2018 CDW54_RS09850 b0286c9021a6caf208f45e5c8f034f1e 341 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 182 321 8.1E-53 T 28-03-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CDW54_RS09850 b0286c9021a6caf208f45e5c8f034f1e 341 SUPERFAMILY SSF48179 182 333 1.55E-55 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CDW54_RS09850 b0286c9021a6caf208f45e5c8f034f1e 341 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 175 199 8.6E-50 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CDW54_RS09850 b0286c9021a6caf208f45e5c8f034f1e 341 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 7 24 8.6E-50 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CDW54_RS09850 b0286c9021a6caf208f45e5c8f034f1e 341 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 240 257 8.6E-50 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CDW54_RS09850 b0286c9021a6caf208f45e5c8f034f1e 341 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 200 224 8.6E-50 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CDW54_RS09850 b0286c9021a6caf208f45e5c8f034f1e 341 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 135 155 8.6E-50 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CDW54_RS09850 b0286c9021a6caf208f45e5c8f034f1e 341 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 57 84 8.6E-50 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CDW54_RS09850 b0286c9021a6caf208f45e5c8f034f1e 341 Gene3D G3DSA:3.40.50.720 2 180 1.3E-43 T 28-03-2018 CDW54_RS09850 b0286c9021a6caf208f45e5c8f034f1e 341 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 3 324 38.314 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CDW54_RS09850 b0286c9021a6caf208f45e5c8f034f1e 341 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 190 211 - T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CDW54_RS09850 b0286c9021a6caf208f45e5c8f034f1e 341 PIRSF PIRSF000114 1 334 2.7E-110 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CDW54_RS09850 b0286c9021a6caf208f45e5c8f034f1e 341 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 5 162 1.4E-58 T 28-03-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CDW54_RS09850 b0286c9021a6caf208f45e5c8f034f1e 341 SUPERFAMILY SSF51735 4 180 9.88E-61 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS09850 b0286c9021a6caf208f45e5c8f034f1e 341 Gene3D G3DSA:1.10.1040.10 191 339 1.4E-53 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CDW54_RS10625 5bc9e0fce3025796d790b58fcc4eeb5d 139 Pfam PF07883 Cupin domain 49 110 3.9E-8 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CDW54_RS10625 5bc9e0fce3025796d790b58fcc4eeb5d 139 SUPERFAMILY SSF51182 18 135 2.67E-27 T 28-03-2018 IPR011051 RmlC-like cupin domain CDW54_RS10625 5bc9e0fce3025796d790b58fcc4eeb5d 139 Gene3D G3DSA:2.60.120.10 13 139 2.3E-26 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CDW54_RS04085 5fa2ffdf84421113b045131b2c58b783 254 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 5 248 2.0E-58 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CDW54_RS04085 5fa2ffdf84421113b045131b2c58b783 254 Pfam PF04452 RNA methyltransferase 18 244 1.3E-69 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CDW54_RS04085 5fa2ffdf84421113b045131b2c58b783 254 Gene3D G3DSA:3.40.1280.10 1 252 6.0E-70 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CDW54_RS04085 5fa2ffdf84421113b045131b2c58b783 254 PIRSF PIRSF015601 1 249 1.0E-55 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CDW54_RS04085 5fa2ffdf84421113b045131b2c58b783 254 SUPERFAMILY SSF88697 1 68 3.73E-15 T 28-03-2018 IPR015947 PUA-like domain CDW54_RS04085 5fa2ffdf84421113b045131b2c58b783 254 SUPERFAMILY SSF75217 72 249 1.66E-50 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CDW54_RS09980 463fe6711f9fde8a754f94356129100e 148 Pfam PF09424 Yqey-like protein 5 146 2.0E-58 T 28-03-2018 IPR019004 Uncharacterised domain YOR215C, mitochondrial CDW54_RS09980 463fe6711f9fde8a754f94356129100e 148 SUPERFAMILY SSF89095 2 147 5.23E-47 T 28-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 CDW54_RS09980 463fe6711f9fde8a754f94356129100e 148 Gene3D G3DSA:1.10.1510.10 1 90 5.0E-29 T 28-03-2018 CDW54_RS09980 463fe6711f9fde8a754f94356129100e 148 Gene3D G3DSA:1.10.10.410 91 147 9.5E-23 T 28-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal CDW54_RS12670 878249c7b0b77ba763f3daa3a434622f 146 Pfam PF07977 FabA-like domain 14 136 2.5E-29 T 28-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CDW54_RS12670 878249c7b0b77ba763f3daa3a434622f 146 SUPERFAMILY SSF54637 4 142 1.19E-38 T 28-03-2018 IPR029069 HotDog domain CDW54_RS12670 878249c7b0b77ba763f3daa3a434622f 146 Gene3D G3DSA:3.10.129.10 1 144 5.3E-44 T 28-03-2018 CDW54_RS12670 878249c7b0b77ba763f3daa3a434622f 146 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 5 144 30.57 T 28-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CDW54_RS12670 878249c7b0b77ba763f3daa3a434622f 146 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 6 141 3.9E-48 T 28-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CDW54_RS05960 745fcfa64064a38d411d54862a7e2b4b 62 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 60 6.5E-24 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS05960 745fcfa64064a38d411d54862a7e2b4b 62 SUPERFAMILY SSF46561 1 60 9.03E-23 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS05960 745fcfa64064a38d411d54862a7e2b4b 62 Pfam PF00831 Ribosomal L29 protein 4 59 6.8E-26 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS05960 745fcfa64064a38d411d54862a7e2b4b 62 ProSitePatterns PS00579 Ribosomal protein L29 signature. 39 53 - T 28-03-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS05960 745fcfa64064a38d411d54862a7e2b4b 62 Gene3D G3DSA:1.10.287.310 1 62 8.0E-25 T 28-03-2018 CDW54_RS05960 745fcfa64064a38d411d54862a7e2b4b 62 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 18.978 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS12420 2fb629c1004b02f7354fa6c4edf9116e 556 Pfam PF01268 Formate--tetrahydrofolate ligase 3 556 1.1E-267 T 28-03-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CDW54_RS12420 2fb629c1004b02f7354fa6c4edf9116e 556 ProSitePatterns PS00722 Formate--tetrahydrofolate ligase signature 2. 328 339 - T 28-03-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CDW54_RS12420 2fb629c1004b02f7354fa6c4edf9116e 556 Hamap MF_01543 Formate--tetrahydrofolate ligase [fhs]. 1 556 48.716 T 28-03-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CDW54_RS12420 2fb629c1004b02f7354fa6c4edf9116e 556 Gene3D G3DSA:3.10.410.10 444 532 3.1E-39 T 28-03-2018 CDW54_RS12420 2fb629c1004b02f7354fa6c4edf9116e 556 Gene3D G3DSA:3.40.50.300 12 233 4.4E-94 T 28-03-2018 CDW54_RS12420 2fb629c1004b02f7354fa6c4edf9116e 556 Gene3D G3DSA:3.40.50.300 234 442 1.3E-69 T 28-03-2018 CDW54_RS12420 2fb629c1004b02f7354fa6c4edf9116e 556 ProSitePatterns PS00721 Formate--tetrahydrofolate ligase signature 1. 103 113 - T 28-03-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CDW54_RS12420 2fb629c1004b02f7354fa6c4edf9116e 556 SUPERFAMILY SSF52540 4 554 2.12E-243 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS05915 06e5f42bca0a118081da8129a877b37a 122 PRINTS PR00971 Ribosomal protein S10 family signature 60 75 4.0E-19 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS05915 06e5f42bca0a118081da8129a877b37a 122 PRINTS PR00971 Ribosomal protein S10 family signature 81 95 4.0E-19 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS05915 06e5f42bca0a118081da8129a877b37a 122 PRINTS PR00971 Ribosomal protein S10 family signature 25 38 4.0E-19 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS05915 06e5f42bca0a118081da8129a877b37a 122 Gene3D G3DSA:3.30.70.600 23 122 2.5E-36 T 28-03-2018 IPR027486 Ribosomal protein S10 domain CDW54_RS05915 06e5f42bca0a118081da8129a877b37a 122 Pfam PF00338 Ribosomal protein S10p/S20e 27 121 1.6E-35 T 28-03-2018 IPR027486 Ribosomal protein S10 domain CDW54_RS05915 06e5f42bca0a118081da8129a877b37a 122 ProSitePatterns PS00361 Ribosomal protein S10 signature. 49 64 - T 28-03-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS05915 06e5f42bca0a118081da8129a877b37a 122 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 23 122 27.759 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS05915 06e5f42bca0a118081da8129a877b37a 122 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 24 121 5.7E-46 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS05915 06e5f42bca0a118081da8129a877b37a 122 SUPERFAMILY SSF54999 25 122 4.05E-38 T 28-03-2018 IPR027486 Ribosomal protein S10 domain CDW54_RS05915 06e5f42bca0a118081da8129a877b37a 122 SMART SM01403 27 121 5.3E-59 T 28-03-2018 IPR027486 Ribosomal protein S10 domain CDW54_RS04865 375902c58412a0eebc44bc7f960efae7 284 PIRSF PIRSF038471 1 284 8.5E-65 T 28-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 CDW54_RS04865 375902c58412a0eebc44bc7f960efae7 284 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 4 280 4.5E-41 T 28-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 CDW54_RS04865 375902c58412a0eebc44bc7f960efae7 284 Pfam PF04085 rod shape-determining protein MreC 126 278 5.7E-40 T 28-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 CDW54_RS10000 5f29e9d36ae4cebd84906b06ef32f995 158 SUPERFAMILY SSF55486 3 157 8.79E-43 T 28-03-2018 CDW54_RS10000 5f29e9d36ae4cebd84906b06ef32f995 158 Gene3D G3DSA:3.40.390.30 1 158 2.4E-49 T 28-03-2018 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 CDW54_RS10000 5f29e9d36ae4cebd84906b06ef32f995 158 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 5 158 22.993 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CDW54_RS10000 5f29e9d36ae4cebd84906b06ef32f995 158 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 38 155 2.7E-41 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CDW54_RS10000 5f29e9d36ae4cebd84906b06ef32f995 158 Pfam PF02130 Uncharacterized protein family UPF0054 12 153 3.0E-46 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CDW54_RS10000 5f29e9d36ae4cebd84906b06ef32f995 158 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 124 134 - T 28-03-2018 IPR020549 Endoribonuclease YbeY, conserved site CDW54_RS02575 bd4797ebd29c55a6e3734c00dc4471dd 215 SUPERFAMILY SSF51735 84 206 1.08E-23 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS02575 bd4797ebd29c55a6e3734c00dc4471dd 215 SMART SM00881 81 182 6.0E-11 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CDW54_RS02575 bd4797ebd29c55a6e3734c00dc4471dd 215 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 3 211 34.337 T 28-03-2018 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 CDW54_RS02575 bd4797ebd29c55a6e3734c00dc4471dd 215 SUPERFAMILY SSF46785 9 81 9.98E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS02575 bd4797ebd29c55a6e3734c00dc4471dd 215 Gene3D G3DSA:1.10.10.10 6 72 1.4E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS02575 bd4797ebd29c55a6e3734c00dc4471dd 215 Pfam PF06971 Putative DNA-binding protein N-terminus 8 55 4.5E-17 T 28-03-2018 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 CDW54_RS02575 bd4797ebd29c55a6e3734c00dc4471dd 215 Pfam PF02629 CoA binding domain 84 180 2.9E-16 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CDW54_RS02575 bd4797ebd29c55a6e3734c00dc4471dd 215 Gene3D G3DSA:3.40.50.720 73 187 3.3E-17 T 28-03-2018 CDW54_RS09695 9034a9419ce5544155f1ae3cbcbf8fe3 294 SUPERFAMILY SSF53067 2 288 2.73E-51 T 28-03-2018 CDW54_RS09695 9034a9419ce5544155f1ae3cbcbf8fe3 294 Gene3D G3DSA:3.30.420.40 115 293 4.1E-38 T 28-03-2018 CDW54_RS09695 9034a9419ce5544155f1ae3cbcbf8fe3 294 Gene3D G3DSA:3.30.420.40 2 114 8.4E-20 T 28-03-2018 CDW54_RS09695 9034a9419ce5544155f1ae3cbcbf8fe3 294 Pfam PF00480 ROK family 8 284 1.7E-36 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CDW54_RS08225 894045670a64ef3cab528a59f13dfede 428 Gene3D G3DSA:1.20.1250.20 6 202 5.3E-19 T 28-03-2018 CDW54_RS08225 894045670a64ef3cab528a59f13dfede 428 Pfam PF07690 Major Facilitator Superfamily 20 370 1.5E-25 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDW54_RS08225 894045670a64ef3cab528a59f13dfede 428 Gene3D G3DSA:1.20.1250.20 212 421 3.7E-23 T 28-03-2018 CDW54_RS08225 894045670a64ef3cab528a59f13dfede 428 SUPERFAMILY SSF103473 12 405 7.72E-53 T 28-03-2018 IPR020846 Major facilitator superfamily domain CDW54_RS08745 08b591724670712868bbfc979457511e 417 Pfam PF14501 GHKL domain 311 408 2.6E-6 T 28-03-2018 IPR032834 Sensor histidine kinase NatK, C-terminal domain CDW54_RS08745 08b591724670712868bbfc979457511e 417 SUPERFAMILY SSF55874 272 386 1.14E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS08745 08b591724670712868bbfc979457511e 417 Gene3D G3DSA:3.30.565.10 259 409 4.1E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS11465 cc0dc2a38ef493b4d19e2f5012a98b60 373 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 9 350 9.7E-74 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CDW54_RS11465 cc0dc2a38ef493b4d19e2f5012a98b60 373 Gene3D G3DSA:3.40.1390.30 1 129 9.0E-34 T 28-03-2018 CDW54_RS11465 cc0dc2a38ef493b4d19e2f5012a98b60 373 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 5 369 1.9E-70 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CDW54_RS11465 cc0dc2a38ef493b4d19e2f5012a98b60 373 SUPERFAMILY SSF102705 6 372 1.83E-121 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CDW54_RS11465 cc0dc2a38ef493b4d19e2f5012a98b60 373 PIRSF PIRSF037489 1 373 6.2E-147 T 28-03-2018 IPR017221 GTP cyclohydrolase 1 type 2//Nif3, bacteria CDW54_RS11465 cc0dc2a38ef493b4d19e2f5012a98b60 373 Gene3D G3DSA:3.30.70.120 132 237 1.5E-36 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CDW54_RS11465 cc0dc2a38ef493b4d19e2f5012a98b60 373 Gene3D G3DSA:3.40.1390.30 245 366 9.3E-14 T 28-03-2018 CDW54_RS11280 a5fc491d75acebf46b1520a5e81b2951 388 ProSitePatterns PS00789 Chorismate synthase signature 3. 337 353 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CDW54_RS11280 a5fc491d75acebf46b1520a5e81b2951 388 Pfam PF01264 Chorismate synthase 1 363 1.5E-119 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CDW54_RS11280 a5fc491d75acebf46b1520a5e81b2951 388 Gene3D G3DSA:3.60.150.10 1 388 5.4E-135 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CDW54_RS11280 a5fc491d75acebf46b1520a5e81b2951 388 TIGRFAM TIGR00033 aroC: chorismate synthase 1 367 2.2E-128 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CDW54_RS11280 a5fc491d75acebf46b1520a5e81b2951 388 SUPERFAMILY SSF103263 1 387 5.1E-147 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CDW54_RS11280 a5fc491d75acebf46b1520a5e81b2951 388 Hamap MF_00300 Chorismate synthase [aroC]. 1 370 35.182 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CDW54_RS11280 a5fc491d75acebf46b1520a5e81b2951 388 ProSitePatterns PS00788 Chorismate synthase signature 2. 129 145 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CDW54_RS11280 a5fc491d75acebf46b1520a5e81b2951 388 ProSitePatterns PS00787 Chorismate synthase signature 1. 7 22 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CDW54_RS11280 a5fc491d75acebf46b1520a5e81b2951 388 PIRSF PIRSF001456 1 385 3.7E-126 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CDW54_RS12620 918ba0f3a065969b2a366192e6a92f53 765 Pfam PF10141 Single-strand DNA-specific exonuclease, C terminal domain 562 763 2.9E-63 T 28-03-2018 IPR018779 Single-stranded-DNA-specific exonuclease RecJ, C-terminal CDW54_RS12620 918ba0f3a065969b2a366192e6a92f53 765 Pfam PF02272 DHHA1 domain 315 435 1.3E-17 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CDW54_RS12620 918ba0f3a065969b2a366192e6a92f53 765 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 29 556 1.8E-181 T 28-03-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 CDW54_RS12620 918ba0f3a065969b2a366192e6a92f53 765 Gene3D G3DSA:3.90.1640.10 63 240 6.1E-27 T 28-03-2018 CDW54_RS12620 918ba0f3a065969b2a366192e6a92f53 765 SUPERFAMILY SSF64182 58 435 5.36E-113 T 28-03-2018 CDW54_RS12620 918ba0f3a065969b2a366192e6a92f53 765 Pfam PF01368 DHH family 83 226 4.0E-11 T 28-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CDW54_RS05440 9e14202c2926ab51fb0b678a32411869 413 Gene3D G3DSA:3.20.20.70 10 175 2.2E-7 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDW54_RS05440 9e14202c2926ab51fb0b678a32411869 413 Pfam PF01136 Peptidase family U32 85 314 1.3E-84 T 28-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 CDW54_RS05440 9e14202c2926ab51fb0b678a32411869 413 Pfam PF16325 Peptidase family U32 C-terminal domain 330 410 3.3E-27 T 28-03-2018 IPR032525 Peptidase family U32, C-terminal CDW54_RS05440 9e14202c2926ab51fb0b678a32411869 413 ProSitePatterns PS01276 Peptidase family U32 signature. 167 185 - T 28-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 CDW54_RS08450 f26ae1a8fe6e092c2b51c1a68292406f 111 Pfam PF05521 Phage head-tail joining protein 12 107 2.5E-18 T 28-03-2018 IPR008767 Bacteriophage SPP1, head-tail adaptor CDW54_RS08450 f26ae1a8fe6e092c2b51c1a68292406f 111 TIGRFAM TIGR01563 gp16_SPP1: putative phage head-tail adaptor 10 97 1.4E-11 T 28-03-2018 IPR008767 Bacteriophage SPP1, head-tail adaptor CDW54_RS01990 de9fb5154cd13dce72c06279450a2ec3 337 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 117 1.1E-20 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CDW54_RS01990 de9fb5154cd13dce72c06279450a2ec3 337 SUPERFAMILY SSF51735 2 135 2.33E-33 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS01990 de9fb5154cd13dce72c06279450a2ec3 337 SUPERFAMILY SSF55347 154 291 1.5E-14 T 28-03-2018 CDW54_RS01990 de9fb5154cd13dce72c06279450a2ec3 337 Gene3D G3DSA:3.30.360.10 151 333 4.2E-20 T 28-03-2018 CDW54_RS01990 de9fb5154cd13dce72c06279450a2ec3 337 Gene3D G3DSA:3.40.50.720 1 150 4.5E-31 T 28-03-2018 CDW54_RS05025 ba5480bb1035ba8b78a9fa623ad0d8f7 192 PIRSF PIRSF000847 1 192 8.9E-48 T 28-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CDW54_RS05025 ba5480bb1035ba8b78a9fa623ad0d8f7 192 Pfam PF01066 CDP-alcohol phosphatidyltransferase 2 81 6.0E-16 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CDW54_RS05025 ba5480bb1035ba8b78a9fa623ad0d8f7 192 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 59 81 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CDW54_RS05025 ba5480bb1035ba8b78a9fa623ad0d8f7 192 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 1 186 5.8E-52 T 28-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CDW54_RS08530 9bc04b87f1a469d38718dcd6c942c15b 141 SUPERFAMILY SSF53335 42 127 3.24E-5 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDW54_RS01655 ce643d5bd51dd68907008ad8f394202c 147 Pfam PF13673 Acetyltransferase (GNAT) domain 35 143 1.1E-21 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CDW54_RS01655 ce643d5bd51dd68907008ad8f394202c 147 Gene3D G3DSA:3.40.630.30 1 144 2.5E-39 T 28-03-2018 CDW54_RS01655 ce643d5bd51dd68907008ad8f394202c 147 SUPERFAMILY SSF55729 10 143 2.99E-38 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDW54_RS06260 dd7a68e1cbfefd8d678b338fda8a6a8d 243 Pfam PF13731 WxL domain surface cell wall-binding 32 241 1.7E-65 T 28-03-2018 IPR027994 WxL domain CDW54_RS03840 8818a4870288c250fce11abf7910395b 140 Pfam PF00298 Ribosomal protein L11, RNA binding domain 71 139 3.1E-27 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CDW54_RS03840 8818a4870288c250fce11abf7910395b 140 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 66 3.4E-30 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal CDW54_RS03840 8818a4870288c250fce11abf7910395b 140 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 140 31.105 T 28-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 CDW54_RS03840 8818a4870288c250fce11abf7910395b 140 ProSitePatterns PS00359 Ribosomal protein L11 signature. 126 140 - T 28-03-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS03840 8818a4870288c250fce11abf7910395b 140 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 70 8.0E-14 T 28-03-2018 CDW54_RS03840 8818a4870288c250fce11abf7910395b 140 Gene3D G3DSA:3.30.1550.10 3 71 1.1E-34 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal CDW54_RS03840 8818a4870288c250fce11abf7910395b 140 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 140 1.8E-65 T 28-03-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS03840 8818a4870288c250fce11abf7910395b 140 SUPERFAMILY SSF54747 3 72 2.75E-29 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal CDW54_RS03840 8818a4870288c250fce11abf7910395b 140 SMART SM00649 9 140 1.6E-87 T 28-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 CDW54_RS03840 8818a4870288c250fce11abf7910395b 140 SUPERFAMILY SSF46906 67 140 1.01E-28 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CDW54_RS03840 8818a4870288c250fce11abf7910395b 140 Gene3D G3DSA:1.10.10.250 72 140 6.6E-27 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CDW54_RS02780 5c60ea7c3a21791f54c583509c27df6c 104 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 7 99 6.8E-34 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CDW54_RS02780 5c60ea7c3a21791f54c583509c27df6c 104 SUPERFAMILY SSF46973 2 99 5.36E-33 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CDW54_RS02780 5c60ea7c3a21791f54c583509c27df6c 104 Gene3D G3DSA:1.20.58.80 2 100 6.8E-35 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CDW54_RS02780 5c60ea7c3a21791f54c583509c27df6c 104 PIRSF PIRSF000699 1 104 2.1E-35 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CDW54_RS03550 deb5f1e1f8c379820f1e15a8d15972a7 466 Gene3D G3DSA:1.20.1250.20 226 463 1.5E-38 T 28-03-2018 CDW54_RS03550 deb5f1e1f8c379820f1e15a8d15972a7 466 PRINTS PR00171 Sugar transporter signature 264 274 7.8E-28 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CDW54_RS03550 deb5f1e1f8c379820f1e15a8d15972a7 466 PRINTS PR00171 Sugar transporter signature 353 374 7.8E-28 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CDW54_RS03550 deb5f1e1f8c379820f1e15a8d15972a7 466 PRINTS PR00171 Sugar transporter signature 20 30 7.8E-28 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CDW54_RS03550 deb5f1e1f8c379820f1e15a8d15972a7 466 PRINTS PR00171 Sugar transporter signature 107 126 7.8E-28 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CDW54_RS03550 deb5f1e1f8c379820f1e15a8d15972a7 466 PRINTS PR00171 Sugar transporter signature 376 388 7.8E-28 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CDW54_RS03550 deb5f1e1f8c379820f1e15a8d15972a7 466 ProSitePatterns PS00217 Sugar transport proteins signature 2. 112 137 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CDW54_RS03550 deb5f1e1f8c379820f1e15a8d15972a7 466 ProSitePatterns PS00216 Sugar transport proteins signature 1. 68 85 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CDW54_RS03550 deb5f1e1f8c379820f1e15a8d15972a7 466 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 7 448 9.7E-107 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CDW54_RS03550 deb5f1e1f8c379820f1e15a8d15972a7 466 Pfam PF00083 Sugar (and other) transporter 14 450 4.7E-113 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CDW54_RS03550 deb5f1e1f8c379820f1e15a8d15972a7 466 Gene3D G3DSA:1.20.1250.20 2 210 5.0E-35 T 28-03-2018 CDW54_RS03550 deb5f1e1f8c379820f1e15a8d15972a7 466 SUPERFAMILY SSF103473 237 450 1.2E-78 T 28-03-2018 IPR020846 Major facilitator superfamily domain CDW54_RS03550 deb5f1e1f8c379820f1e15a8d15972a7 466 SUPERFAMILY SSF103473 1 207 1.2E-78 T 28-03-2018 IPR020846 Major facilitator superfamily domain CDW54_RS09275 98bd1f63950e40fe7f02d57c198c29cc 278 Gene3D G3DSA:1.20.120.540 62 188 1.1E-4 T 28-03-2018 IPR027378 Cyclic nucleotide-regulated ion channel, N-terminal domain Reactome: R-HSA-159418|Reactome: R-HSA-879518 CDW54_RS09275 98bd1f63950e40fe7f02d57c198c29cc 278 Pfam PF01925 Sulfite exporter TauE/SafE 7 247 1.0E-36 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CDW54_RS11650 d409b331364b63ed9969d0040a9f0fd4 331 Pfam PF03612 Sorbitol phosphotransferase enzyme II N-terminus 5 183 4.5E-76 T 28-03-2018 IPR011618 Sorbitol phosphotransferase enzyme II, N-terminal GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 CDW54_RS11650 d409b331364b63ed9969d0040a9f0fd4 331 Pfam PF07663 Sorbitol phosphotransferase enzyme II C-terminus 238 330 2.9E-45 T 28-03-2018 IPR011638 Sorbitol phosphotransferase enzyme II, C-terminal GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 CDW54_RS11650 d409b331364b63ed9969d0040a9f0fd4 331 TIGRFAM TIGR00825 EIIBC-GUT: PTS system, glucitol/sorbitol-specific, IIBC component 4 330 1.7E-148 T 28-03-2018 IPR004702 Phosphotransferease, sorbitol phosphotransferase enzyme II GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 CDW54_RS05580 ef007b58886e8cc62c026a3819d76e2d 237 SUPERFAMILY SSF53335 1 236 1.71E-46 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDW54_RS05580 ef007b58886e8cc62c026a3819d76e2d 237 Gene3D G3DSA:3.40.50.150 3 237 2.4E-38 T 28-03-2018 CDW54_RS05580 ef007b58886e8cc62c026a3819d76e2d 237 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 14 213 27.739 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CDW54_RS05580 ef007b58886e8cc62c026a3819d76e2d 237 Pfam PF02527 rRNA small subunit methyltransferase G 21 197 1.1E-51 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CDW54_RS05580 ef007b58886e8cc62c026a3819d76e2d 237 PIRSF PIRSF003078 1 219 6.9E-54 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CDW54_RS05580 ef007b58886e8cc62c026a3819d76e2d 237 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 26 216 5.1E-49 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CDW54_RS02160 0fb04aa3bd997acb3322ea41b5db2bb8 81 Pfam PF04226 Transglycosylase associated protein 33 77 1.5E-11 T 28-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 CDW54_RS02550 1b8fd4eebd9e65efccf164af9f2533f2 66 SMART SM00357 3 66 9.5E-32 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CDW54_RS02550 1b8fd4eebd9e65efccf164af9f2533f2 66 PIRSF PIRSF002599 1 66 3.6E-25 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 CDW54_RS02550 1b8fd4eebd9e65efccf164af9f2533f2 66 Gene3D G3DSA:2.40.50.140 1 66 4.4E-29 T 28-03-2018 CDW54_RS02550 1b8fd4eebd9e65efccf164af9f2533f2 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 5.9E-32 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CDW54_RS02550 1b8fd4eebd9e65efccf164af9f2533f2 66 PRINTS PR00050 Cold shock protein signature 4 19 3.8E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CDW54_RS02550 1b8fd4eebd9e65efccf164af9f2533f2 66 PRINTS PR00050 Cold shock protein signature 39 57 3.8E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CDW54_RS02550 1b8fd4eebd9e65efccf164af9f2533f2 66 PRINTS PR00050 Cold shock protein signature 24 33 3.8E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CDW54_RS02550 1b8fd4eebd9e65efccf164af9f2533f2 66 SUPERFAMILY SSF50249 1 64 1.92E-25 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDW54_RS02550 1b8fd4eebd9e65efccf164af9f2533f2 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 28-03-2018 IPR019844 Cold-shock conserved site CDW54_RS10160 1251a349145bcd32dc7fc22346da42e7 422 Gene3D G3DSA:1.10.3080.10 3 406 2.8E-55 T 28-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 CDW54_RS10160 1251a349145bcd32dc7fc22346da42e7 422 Pfam PF00654 Voltage gated chloride channel 61 390 2.8E-65 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CDW54_RS10160 1251a349145bcd32dc7fc22346da42e7 422 SUPERFAMILY SSF81340 8 401 8.76E-84 T 28-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 CDW54_RS10160 1251a349145bcd32dc7fc22346da42e7 422 PRINTS PR00762 Chloride channel signature 101 120 7.6E-5 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CDW54_RS10160 1251a349145bcd32dc7fc22346da42e7 422 PRINTS PR00762 Chloride channel signature 152 171 7.6E-5 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CDW54_RS03080 a691fb364d3fd08a0a24b61a1cecb2e6 334 Pfam PF01380 SIS domain 37 137 4.8E-11 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CDW54_RS03080 a691fb364d3fd08a0a24b61a1cecb2e6 334 PIRSF PIRSF009290 1 334 3.2E-84 T 28-03-2018 IPR024713 Fructosamine deglycase FrlB CDW54_RS03080 a691fb364d3fd08a0a24b61a1cecb2e6 334 Gene3D G3DSA:3.40.50.10490 157 322 2.4E-9 T 28-03-2018 CDW54_RS03080 a691fb364d3fd08a0a24b61a1cecb2e6 334 SUPERFAMILY SSF53697 8 334 1.24E-55 T 28-03-2018 CDW54_RS03080 a691fb364d3fd08a0a24b61a1cecb2e6 334 Gene3D G3DSA:3.40.50.10490 2 154 4.5E-25 T 28-03-2018 CDW54_RS06400 ce1d0e950412952e1cc885e161556e0f 333 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 7 237 2.9E-116 T 28-03-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 CDW54_RS06400 ce1d0e950412952e1cc885e161556e0f 333 SUPERFAMILY SSF46785 259 331 7.07E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS06400 ce1d0e950412952e1cc885e161556e0f 333 Gene3D G3DSA:1.10.8.60 201 256 2.0E-32 T 28-03-2018 CDW54_RS06400 ce1d0e950412952e1cc885e161556e0f 333 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 252 331 3.0E-40 T 28-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 CDW54_RS06400 ce1d0e950412952e1cc885e161556e0f 333 SUPERFAMILY SSF52540 22 254 1.54E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS06400 ce1d0e950412952e1cc885e161556e0f 333 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 333 168.912 T 28-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 CDW54_RS06400 ce1d0e950412952e1cc885e161556e0f 333 SMART SM00382 53 184 6.5E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS06400 ce1d0e950412952e1cc885e161556e0f 333 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 26 328 3.2E-143 T 28-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 CDW54_RS06400 ce1d0e950412952e1cc885e161556e0f 333 Gene3D G3DSA:3.40.50.300 11 200 4.6E-27 T 28-03-2018 CDW54_RS06400 ce1d0e950412952e1cc885e161556e0f 333 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 255 328 2.2E-32 T 28-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 CDW54_RS06400 ce1d0e950412952e1cc885e161556e0f 333 Gene3D G3DSA:1.10.10.10 259 329 1.4E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS05395 7c93b45a8a7639de1969faf7c707e244 328 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 208 220 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CDW54_RS05395 7c93b45a8a7639de1969faf7c707e244 328 Gene3D G3DSA:1.10.600.10 2 328 1.3E-86 T 28-03-2018 IPR008949 Isoprenoid synthase domain CDW54_RS05395 7c93b45a8a7639de1969faf7c707e244 328 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 85 99 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CDW54_RS05395 7c93b45a8a7639de1969faf7c707e244 328 Pfam PF00348 Polyprenyl synthetase 35 276 2.6E-64 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 CDW54_RS05395 7c93b45a8a7639de1969faf7c707e244 328 SUPERFAMILY SSF48576 4 327 4.75E-78 T 28-03-2018 IPR008949 Isoprenoid synthase domain CDW54_RS04890 758e1300d13f94956bae1e44486533b2 246 Gene3D G3DSA:3.60.40.10 1 241 2.3E-49 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CDW54_RS04890 758e1300d13f94956bae1e44486533b2 246 SMART SM00332 1 239 9.3E-26 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CDW54_RS04890 758e1300d13f94956bae1e44486533b2 246 SMART SM00331 4 241 4.2E-45 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CDW54_RS04890 758e1300d13f94956bae1e44486533b2 246 SUPERFAMILY SSF81606 2 240 3.79E-66 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CDW54_RS04890 758e1300d13f94956bae1e44486533b2 246 Pfam PF13672 Protein phosphatase 2C 11 231 8.1E-21 T 28-03-2018 CDW54_RS00780 33e7d48b59f9a6375bcd6748b2894dab 258 Hamap MF_00052_B Ribonuclease HII [rnhB]. 72 250 37.4 T 28-03-2018 IPR022898 Ribonuclease HII GO:0004523 CDW54_RS00780 33e7d48b59f9a6375bcd6748b2894dab 258 Pfam PF01351 Ribonuclease HII 74 249 2.4E-39 T 28-03-2018 IPR024567 Ribonuclease HII/HIII domain CDW54_RS00780 33e7d48b59f9a6375bcd6748b2894dab 258 SUPERFAMILY SSF53098 62 255 5.92E-71 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS00780 33e7d48b59f9a6375bcd6748b2894dab 258 Gene3D G3DSA:3.30.420.10 48 258 3.5E-72 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS02120 adb9d4a85ff88d43d24c4cfe615d2081 272 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 5 238 6.9E-82 T 28-03-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 CDW54_RS02120 adb9d4a85ff88d43d24c4cfe615d2081 272 PIRSF PIRSF005578 1 265 2.0E-97 T 28-03-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 CDW54_RS02120 adb9d4a85ff88d43d24c4cfe615d2081 272 Gene3D G3DSA:3.40.50.150 64 272 3.4E-61 T 28-03-2018 CDW54_RS02120 adb9d4a85ff88d43d24c4cfe615d2081 272 Pfam PF01728 FtsJ-like methyltransferase 61 243 7.2E-19 T 28-03-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 CDW54_RS02120 adb9d4a85ff88d43d24c4cfe615d2081 272 SUPERFAMILY SSF55174 2 70 1.77E-7 T 28-03-2018 CDW54_RS02120 adb9d4a85ff88d43d24c4cfe615d2081 272 Gene3D G3DSA:3.10.290.10 1 63 3.7E-12 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDW54_RS02120 adb9d4a85ff88d43d24c4cfe615d2081 272 SUPERFAMILY SSF53335 52 246 7.48E-23 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDW54_RS11630 c6a3a08a8fa651f5bd8eec46dcab6ee0 266 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CDW54_RS11630 c6a3a08a8fa651f5bd8eec46dcab6ee0 266 Pfam PF00106 short chain dehydrogenase 10 202 7.2E-50 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS11630 c6a3a08a8fa651f5bd8eec46dcab6ee0 266 SUPERFAMILY SSF51735 9 264 1.5E-63 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS11630 c6a3a08a8fa651f5bd8eec46dcab6ee0 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 227 247 3.3E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS11630 c6a3a08a8fa651f5bd8eec46dcab6ee0 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 3.3E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS11630 c6a3a08a8fa651f5bd8eec46dcab6ee0 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 3.3E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS11630 c6a3a08a8fa651f5bd8eec46dcab6ee0 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 3.3E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS11630 c6a3a08a8fa651f5bd8eec46dcab6ee0 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 3.3E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS11630 c6a3a08a8fa651f5bd8eec46dcab6ee0 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 3.3E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS11630 c6a3a08a8fa651f5bd8eec46dcab6ee0 266 Gene3D G3DSA:3.40.50.720 5 265 2.2E-56 T 28-03-2018 CDW54_RS11630 c6a3a08a8fa651f5bd8eec46dcab6ee0 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 4.3E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS11630 c6a3a08a8fa651f5bd8eec46dcab6ee0 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 4.3E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS11630 c6a3a08a8fa651f5bd8eec46dcab6ee0 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 4.3E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDW54_RS05080 4a6783491dfffa7fc12d494153b2f872 131 SUPERFAMILY SSF69065 3 126 3.14E-45 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CDW54_RS05080 4a6783491dfffa7fc12d494153b2f872 131 PIRSF PIRSF005520 1 131 7.0E-55 T 28-03-2018 IPR008226 Mini-ribonuclease 3 family CDW54_RS05080 4a6783491dfffa7fc12d494153b2f872 131 Gene3D G3DSA:1.10.1520.10 1 131 2.2E-22 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CDW54_RS05080 4a6783491dfffa7fc12d494153b2f872 131 Pfam PF00636 Ribonuclease III domain 11 110 3.5E-16 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CDW54_RS05080 4a6783491dfffa7fc12d494153b2f872 131 SMART SM00535 5 131 0.0053 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CDW54_RS05080 4a6783491dfffa7fc12d494153b2f872 131 Hamap MF_01468 Mini-ribonuclease 3 [mrnC]. 1 127 30.266 T 28-03-2018 IPR008226 Mini-ribonuclease 3 family CDW54_RS07415 d59108a7af1148c01f747ea1f669e6b8 104 Gene3D G3DSA:3.40.1260.10 1 104 7.3E-25 T 28-03-2018 CDW54_RS07415 d59108a7af1148c01f747ea1f669e6b8 104 Pfam PF02635 DsrE/DsrF-like family 51 104 2.1E-9 T 28-03-2018 IPR003787 Sulphur relay, DsrE/F-like protein CDW54_RS07415 d59108a7af1148c01f747ea1f669e6b8 104 SUPERFAMILY SSF75169 1 104 9.71E-20 T 28-03-2018 IPR027396 DsrEFH-like CDW54_RS11590 dcfdc27108d16a8071a3651132fc83bb 130 Gene3D G3DSA:3.10.180.10 1 130 1.1E-19 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDW54_RS11590 dcfdc27108d16a8071a3651132fc83bb 130 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 3 128 1.6E-23 T 28-03-2018 IPR028973 PhnB-like CDW54_RS11590 dcfdc27108d16a8071a3651132fc83bb 130 PIRSF PIRSF021700 1 130 1.2E-24 T 28-03-2018 IPR009725 Predicted 3-demethylubiquinone-9 3-methyltransferase CDW54_RS11590 dcfdc27108d16a8071a3651132fc83bb 130 SUPERFAMILY SSF54593 1 128 4.23E-27 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDW54_RS08390 7c982d10a352e20f43b4859040ab7e8c 301 Pfam PF08708 Primase C terminal 1 (PriCT-1) 236 297 1.8E-13 T 28-03-2018 IPR014820 Primase, C-terminal 1 CDW54_RS08390 7c982d10a352e20f43b4859040ab7e8c 301 SMART SM00942 234 299 7.2E-15 T 28-03-2018 IPR014820 Primase, C-terminal 1 CDW54_RS06175 8d8599d79c464427eed454f06897195f 320 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 318 2.4E-39 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS06175 8d8599d79c464427eed454f06897195f 320 Gene3D G3DSA:1.10.3720.10 1 307 2.5E-39 T 28-03-2018 CDW54_RS06175 8d8599d79c464427eed454f06897195f 320 SUPERFAMILY SSF161098 187 306 5.76E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS06175 8d8599d79c464427eed454f06897195f 320 SUPERFAMILY SSF161098 90 159 5.76E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS01875 b1dad8b3cdc71f519cc8697fd115bc1c 190 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 2 179 2.4E-69 T 28-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CDW54_RS01875 b1dad8b3cdc71f519cc8697fd115bc1c 190 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 178 1.0E-95 T 28-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CDW54_RS01875 b1dad8b3cdc71f519cc8697fd115bc1c 190 SUPERFAMILY SSF51182 1 181 8.45E-75 T 28-03-2018 IPR011051 RmlC-like cupin domain CDW54_RS01875 b1dad8b3cdc71f519cc8697fd115bc1c 190 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 178 1.2E-71 T 28-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CDW54_RS01875 b1dad8b3cdc71f519cc8697fd115bc1c 190 Gene3D G3DSA:2.60.120.10 1 186 3.8E-74 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CDW54_RS08345 1ea0368f71b44d315601540a3dc4b973 411 Gene3D G3DSA:3.90.1150.10 282 402 2.7E-44 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDW54_RS08345 1ea0368f71b44d315601540a3dc4b973 411 Pfam PF00266 Aminotransferase class-V 24 395 3.0E-158 T 28-03-2018 IPR000192 Aminotransferase class V domain CDW54_RS08345 1ea0368f71b44d315601540a3dc4b973 411 Gene3D G3DSA:3.40.640.10 32 281 1.4E-62 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDW54_RS08345 1ea0368f71b44d315601540a3dc4b973 411 PIRSF PIRSF005572 21 407 2.0E-49 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CDW54_RS08345 1ea0368f71b44d315601540a3dc4b973 411 SUPERFAMILY SSF53383 3 401 2.96E-130 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDW54_RS08345 1ea0368f71b44d315601540a3dc4b973 411 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 216 235 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CDW54_RS08345 1ea0368f71b44d315601540a3dc4b973 411 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 5 407 6.3E-189 T 28-03-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CDW54_RS07580 38353de0b08b74b2cde7bdb805874b90 147 Pfam PF13508 Acetyltransferase (GNAT) domain 49 122 2.2E-14 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CDW54_RS07580 38353de0b08b74b2cde7bdb805874b90 147 Gene3D G3DSA:3.40.630.30 2 146 3.2E-21 T 28-03-2018 CDW54_RS07580 38353de0b08b74b2cde7bdb805874b90 147 SUPERFAMILY SSF55729 8 132 8.8E-23 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDW54_RS01425 3832ec5e9065a462b19519c8f7fe669f 398 PRINTS PR01035 Tetracycline resistance protein signature 136 158 8.1E-11 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CDW54_RS01425 3832ec5e9065a462b19519c8f7fe669f 398 PRINTS PR01035 Tetracycline resistance protein signature 18 34 8.1E-11 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CDW54_RS01425 3832ec5e9065a462b19519c8f7fe669f 398 PRINTS PR01035 Tetracycline resistance protein signature 48 67 8.1E-11 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CDW54_RS01425 3832ec5e9065a462b19519c8f7fe669f 398 PRINTS PR01035 Tetracycline resistance protein signature 279 300 8.1E-11 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CDW54_RS01425 3832ec5e9065a462b19519c8f7fe669f 398 PRINTS PR01035 Tetracycline resistance protein signature 340 363 8.1E-11 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CDW54_RS01425 3832ec5e9065a462b19519c8f7fe669f 398 Pfam PF00083 Sugar (and other) transporter 250 388 4.0E-13 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CDW54_RS01425 3832ec5e9065a462b19519c8f7fe669f 398 Gene3D G3DSA:1.20.1250.20 207 397 1.9E-30 T 28-03-2018 CDW54_RS01425 3832ec5e9065a462b19519c8f7fe669f 398 Gene3D G3DSA:1.20.1250.20 2 206 7.8E-34 T 28-03-2018 CDW54_RS01425 3832ec5e9065a462b19519c8f7fe669f 398 Pfam PF07690 Major Facilitator Superfamily 13 248 4.0E-30 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDW54_RS01425 3832ec5e9065a462b19519c8f7fe669f 398 SUPERFAMILY SSF103473 6 394 9.59E-72 T 28-03-2018 IPR020846 Major facilitator superfamily domain CDW54_RS10980 ee3745c77c1489162258404f29d1c15f 347 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 1 328 28.686 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CDW54_RS10980 ee3745c77c1489162258404f29d1c15f 347 Gene3D G3DSA:3.30.450.40 190 341 3.7E-31 T 28-03-2018 IPR029016 GAF domain-like CDW54_RS10980 ee3745c77c1489162258404f29d1c15f 347 SUPERFAMILY SSF55781 70 339 2.55E-62 T 28-03-2018 IPR029016 GAF domain-like CDW54_RS10980 ee3745c77c1489162258404f29d1c15f 347 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 3 333 1.5E-90 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CDW54_RS10980 ee3745c77c1489162258404f29d1c15f 347 PIRSF PIRSF005485 1 339 2.7E-96 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CDW54_RS10980 ee3745c77c1489162258404f29d1c15f 347 SUPERFAMILY SSF46785 1 83 2.72E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS10980 ee3745c77c1489162258404f29d1c15f 347 Gene3D G3DSA:1.10.10.10 1 84 8.8E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS10980 ee3745c77c1489162258404f29d1c15f 347 Pfam PF01628 HrcA protein C terminal domain 104 320 4.7E-46 T 28-03-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 CDW54_RS06955 f94beb1b7b53a2bb8bc5d622d16f69ec 230 Gene3D G3DSA:1.20.5.50 88 163 1.1E-6 T 28-03-2018 CDW54_RS06955 f94beb1b7b53a2bb8bc5d622d16f69ec 230 Gene3D G3DSA:1.20.5.730 33 87 5.3E-5 T 28-03-2018 CDW54_RS06955 f94beb1b7b53a2bb8bc5d622d16f69ec 230 SUPERFAMILY SSF90257 115 220 1.2E-5 T 28-03-2018 CDW54_RS06955 f94beb1b7b53a2bb8bc5d622d16f69ec 230 Gene3D G3DSA:1.20.58.60 164 230 0.16 T 28-03-2018 CDW54_RS06955 f94beb1b7b53a2bb8bc5d622d16f69ec 230 ProDom PD936484 POLYPROTEIN GLYCOPROTEIN M G2 TRANSMEMBRANE NONSTRUCTURAL MEMBRANE CONTAINS: PRECURSOR SIGNAL 87 230 0.003 T 28-03-2018 CDW54_RS08235 7f1fedcffb58d1abb9ad765f497ca5ac 373 Gene3D G3DSA:3.40.50.620 1 213 2.1E-71 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDW54_RS08235 7f1fedcffb58d1abb9ad765f497ca5ac 373 Gene3D G3DSA:2.40.30.10 282 373 5.5E-30 T 28-03-2018 CDW54_RS08235 7f1fedcffb58d1abb9ad765f497ca5ac 373 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 8 360 7.0E-139 T 28-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 CDW54_RS08235 7f1fedcffb58d1abb9ad765f497ca5ac 373 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 7 361 41.844 T 28-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 CDW54_RS08235 7f1fedcffb58d1abb9ad765f497ca5ac 373 SUPERFAMILY SSF52402 5 245 4.19E-60 T 28-03-2018 CDW54_RS08235 7f1fedcffb58d1abb9ad765f497ca5ac 373 Gene3D G3DSA:2.30.30.280 214 280 2.2E-28 T 28-03-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 CDW54_RS08235 7f1fedcffb58d1abb9ad765f497ca5ac 373 Pfam PF03054 tRNA methyl transferase 8 360 1.6E-148 T 28-03-2018 CDW54_RS02660 e299c26fd4a9ec5d038c684deb558e5c 54 Gene3D G3DSA:1.20.5.130 14 54 6.3E-19 T 28-03-2018 IPR023388 Bacteriocin class IIa domain CDW54_RS02660 e299c26fd4a9ec5d038c684deb558e5c 54 Pfam PF01721 Class II bacteriocin 15 47 2.8E-16 T 28-03-2018 IPR002633 Bacteriocin, class IIa GO:0005576|GO:0042742 CDW54_RS02660 e299c26fd4a9ec5d038c684deb558e5c 54 ProDom PD004452 BACTERIOCIN PLASMID PRECURSOR ANTIMICROBIAL ANTIBIOTIC SEQUENCING DIRECT SIGNAL A ENTEROCIN 12 48 2.0E-14 T 28-03-2018 IPR002633 Bacteriocin, class IIa GO:0005576|GO:0042742 CDW54_RS02660 e299c26fd4a9ec5d038c684deb558e5c 54 ProSitePatterns PS60030 Bacteriocin class IIa family signature. 15 26 - T 28-03-2018 IPR023384 Bacteriocin, class IIa, conserved site CDW54_RS06495 836ba1d0fc03a340a9532d267121142b 663 Hamap MF_01522 Low affinity potassium transport system protein kup [kup]. 7 651 27.957 T 28-03-2018 IPR023051 Potassium uptake protein, low affinity, Kup CDW54_RS06495 836ba1d0fc03a340a9532d267121142b 663 Pfam PF02705 K+ potassium transporter 16 555 5.2E-168 T 28-03-2018 IPR003855 Potassium transporter GO:0015079|GO:0016020|GO:0071805 CDW54_RS07035 865537608a571f6d060000a01fb7a48f 413 SUPERFAMILY SSF118215 10 388 1.26E-83 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDW54_RS07035 865537608a571f6d060000a01fb7a48f 413 Pfam PF00375 Sodium:dicarboxylate symporter family 10 388 6.6E-60 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDW54_RS07035 865537608a571f6d060000a01fb7a48f 413 Gene3D G3DSA:1.10.3860.10 1 395 1.9E-69 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDW54_RS07035 865537608a571f6d060000a01fb7a48f 413 PRINTS PR00173 Glutamate-aspartate symporter signature 178 197 7.5E-13 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDW54_RS07035 865537608a571f6d060000a01fb7a48f 413 PRINTS PR00173 Glutamate-aspartate symporter signature 4 24 7.5E-13 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDW54_RS07035 865537608a571f6d060000a01fb7a48f 413 PRINTS PR00173 Glutamate-aspartate symporter signature 280 306 7.5E-13 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDW54_RS07035 865537608a571f6d060000a01fb7a48f 413 PRINTS PR00173 Glutamate-aspartate symporter signature 315 334 7.5E-13 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDW54_RS07035 865537608a571f6d060000a01fb7a48f 413 PRINTS PR00173 Glutamate-aspartate symporter signature 213 232 7.5E-13 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDW54_RS07035 865537608a571f6d060000a01fb7a48f 413 Hamap MF_01582 Serine/threonine transporter SstT [sstT]. 1 397 32.297 T 28-03-2018 IPR023025 Serine/threonine transporter SstT GO:0015293|GO:0015826|GO:0032329 CDW54_RS08340 d6a0dafc75b3ecc8a7231d95688f89f8 428 Pfam PF01458 Uncharacterized protein family (UPF0051) 175 401 1.6E-61 T 28-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 CDW54_RS08340 d6a0dafc75b3ecc8a7231d95688f89f8 428 SUPERFAMILY SSF101960 12 427 1.57E-120 T 28-03-2018 CDW54_RS08340 d6a0dafc75b3ecc8a7231d95688f89f8 428 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 141 418 8.2E-82 T 28-03-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 CDW54_RS02800 3fbae24ba4561d63fedb476335b2a836 297 Gene3D G3DSA:3.30.420.40 2 117 3.6E-19 T 28-03-2018 CDW54_RS02800 3fbae24ba4561d63fedb476335b2a836 297 Gene3D G3DSA:3.30.420.40 118 296 1.1E-26 T 28-03-2018 CDW54_RS02800 3fbae24ba4561d63fedb476335b2a836 297 SUPERFAMILY SSF53067 4 295 4.33E-44 T 28-03-2018 CDW54_RS02800 3fbae24ba4561d63fedb476335b2a836 297 Pfam PF00480 ROK family 6 293 1.5E-37 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CDW54_RS08535 2d473c424a07aad91624e9bb6cd3b4ae 498 Gene3D G3DSA:1.10.10.10 96 159 0.0018 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS08535 2d473c424a07aad91624e9bb6cd3b4ae 498 Pfam PF05043 Mga helix-turn-helix domain 86 164 1.3E-16 T 28-03-2018 IPR007737 Mga helix-turn-helix domain CDW54_RS10145 e3837ec58da4f9dcbffebd6694e649be 167 Gene3D G3DSA:1.10.3210.10 13 163 1.3E-16 T 28-03-2018 CDW54_RS10145 e3837ec58da4f9dcbffebd6694e649be 167 SMART SM00471 34 151 8.8E-4 T 28-03-2018 IPR003607 HD/PDEase domain CDW54_RS10145 e3837ec58da4f9dcbffebd6694e649be 167 Pfam PF01966 HD domain 38 137 3.5E-6 T 28-03-2018 IPR006674 HD domain CDW54_RS10145 e3837ec58da4f9dcbffebd6694e649be 167 SUPERFAMILY SSF109604 16 142 1.86E-22 T 28-03-2018 CDW54_RS07980 ee794c80b042555c6b17091787d2827e 484 Gene3D G3DSA:1.20.1250.20 236 460 2.4E-15 T 28-03-2018 CDW54_RS07980 ee794c80b042555c6b17091787d2827e 484 Gene3D G3DSA:1.20.1250.20 6 234 2.8E-8 T 28-03-2018 CDW54_RS07980 ee794c80b042555c6b17091787d2827e 484 SUPERFAMILY SSF103473 26 457 3.27E-25 T 28-03-2018 IPR020846 Major facilitator superfamily domain CDW54_RS07980 ee794c80b042555c6b17091787d2827e 484 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 8 465 7.8E-136 T 28-03-2018 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 CDW54_RS07980 ee794c80b042555c6b17091787d2827e 484 ProSitePatterns PS00872 Sodium:galactoside symporter family signature. 68 93 - T 28-03-2018 IPR018043 Sodium:galactoside symporter, conserved site GO:0005215|GO:0006814|GO:0016020 CDW54_RS07980 ee794c80b042555c6b17091787d2827e 484 Pfam PF13347 MFS/sugar transport protein 10 445 5.1E-84 T 28-03-2018 CDW54_RS05725 063e63f16234e9c005db2bc0ff5301cb 455 SUPERFAMILY SSF52540 183 441 2.16E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS05725 063e63f16234e9c005db2bc0ff5301cb 455 Pfam PF03796 DnaB-like helicase C terminal domain 185 447 3.8E-111 T 28-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 CDW54_RS05725 063e63f16234e9c005db2bc0ff5301cb 455 SUPERFAMILY SSF48024 8 119 5.1E-37 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CDW54_RS05725 063e63f16234e9c005db2bc0ff5301cb 455 Pfam PF00772 DnaB-like helicase N terminal domain 10 111 1.8E-35 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CDW54_RS05725 063e63f16234e9c005db2bc0ff5301cb 455 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 10 449 3.1E-177 T 28-03-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 CDW54_RS05725 063e63f16234e9c005db2bc0ff5301cb 455 Gene3D G3DSA:3.40.50.300 167 455 2.9E-72 T 28-03-2018 CDW54_RS05725 063e63f16234e9c005db2bc0ff5301cb 455 Gene3D G3DSA:1.10.860.10 2 151 1.9E-46 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CDW54_RS00525 b05d71adff3db4ab1562fc99c0da2516 499 SUPERFAMILY SSF117892 69 211 1.11E-34 T 28-03-2018 IPR001107 Band 7 domain CDW54_RS00525 b05d71adff3db4ab1562fc99c0da2516 499 Pfam PF15975 Flotillin 359 451 3.4E-13 T 28-03-2018 IPR031905 Flotillin, C-terminal domain Reactome: R-HSA-8849932 CDW54_RS00525 b05d71adff3db4ab1562fc99c0da2516 499 Pfam PF01145 SPFH domain / Band 7 family 31 220 1.4E-23 T 28-03-2018 IPR001107 Band 7 domain CDW54_RS00525 b05d71adff3db4ab1562fc99c0da2516 499 SMART SM00244 120 302 1.2E-9 T 28-03-2018 IPR001107 Band 7 domain CDW54_RS12600 e39b23ae4835b399f1365c1589a6abbb 83 Hamap MF_01103 UPF0291 protein . 2 60 16.402 T 28-03-2018 IPR009242 Protein of unknown function DUF896 CDW54_RS12600 e39b23ae4835b399f1365c1589a6abbb 83 Gene3D G3DSA:1.10.287.540 4 56 2.6E-24 T 28-03-2018 CDW54_RS12600 e39b23ae4835b399f1365c1589a6abbb 83 SUPERFAMILY SSF158221 1 42 2.88E-13 T 28-03-2018 CDW54_RS12600 e39b23ae4835b399f1365c1589a6abbb 83 Pfam PF05979 Bacterial protein of unknown function (DUF896) 5 68 3.1E-31 T 28-03-2018 IPR009242 Protein of unknown function DUF896 CDW54_RS10135 ed05e399fdde133d580cf3e803d3edc2 91 Gene3D G3DSA:3.30.70.100 1 91 1.2E-26 T 28-03-2018 CDW54_RS10135 ed05e399fdde133d580cf3e803d3edc2 91 ProSitePatterns PS00150 Acylphosphatase signature 1. 8 18 - T 28-03-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CDW54_RS10135 ed05e399fdde133d580cf3e803d3edc2 91 Pfam PF00708 Acylphosphatase 5 88 3.0E-24 T 28-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CDW54_RS10135 ed05e399fdde133d580cf3e803d3edc2 91 SUPERFAMILY SSF54975 2 89 5.01E-25 T 28-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CDW54_RS10135 ed05e399fdde133d580cf3e803d3edc2 91 PRINTS PR00112 Acylphosphatase signature 24 49 2.6E-6 T 28-03-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CDW54_RS10135 ed05e399fdde133d580cf3e803d3edc2 91 PRINTS PR00112 Acylphosphatase signature 3 18 2.6E-6 T 28-03-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CDW54_RS10135 ed05e399fdde133d580cf3e803d3edc2 91 PRINTS PR00112 Acylphosphatase signature 59 79 2.6E-6 T 28-03-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CDW54_RS09775 c2b64dbc18390493c8b2d93bda36ad6c 285 Pfam PF12849 PBP superfamily domain 29 255 1.1E-37 T 28-03-2018 IPR024370 PBP domain CDW54_RS09775 c2b64dbc18390493c8b2d93bda36ad6c 285 Gene3D G3DSA:3.40.190.10 160 281 2.0E-18 T 28-03-2018 CDW54_RS09775 c2b64dbc18390493c8b2d93bda36ad6c 285 Gene3D G3DSA:3.40.190.10 28 150 2.4E-30 T 28-03-2018 CDW54_RS09775 c2b64dbc18390493c8b2d93bda36ad6c 285 SUPERFAMILY SSF53850 30 277 7.61E-74 T 28-03-2018 CDW54_RS09775 c2b64dbc18390493c8b2d93bda36ad6c 285 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 1 269 4.4E-91 T 28-03-2018 IPR011862 Phosphate binding protein GO:0006810 CDW54_RS03935 cd480ef04b4f133d982d73ffb7c2f4a3 168 TIGRFAM TIGR00185 tRNA_yibK_trmL: tRNA (cytidine(34)-2'-O)-methyltransferase 3 156 4.4E-59 T 28-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CDW54_RS03935 cd480ef04b4f133d982d73ffb7c2f4a3 168 Gene3D G3DSA:3.40.1280.10 1 167 3.4E-36 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CDW54_RS03935 cd480ef04b4f133d982d73ffb7c2f4a3 168 Pfam PF00588 SpoU rRNA Methylase family 3 145 3.6E-29 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CDW54_RS03935 cd480ef04b4f133d982d73ffb7c2f4a3 168 PIRSF PIRSF029256 2 157 4.7E-62 T 28-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CDW54_RS03935 cd480ef04b4f133d982d73ffb7c2f4a3 168 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 3 154 33.733 T 28-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CDW54_RS03935 cd480ef04b4f133d982d73ffb7c2f4a3 168 SUPERFAMILY SSF75217 3 155 1.05E-38 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CDW54_RS10620 b972be15d2a5a5287cf2842314a2b0b1 114 Gene3D G3DSA:1.20.1290.10 1 114 6.5E-30 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CDW54_RS10620 b972be15d2a5a5287cf2842314a2b0b1 114 Pfam PF02627 Carboxymuconolactone decarboxylase family 17 101 9.3E-20 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CDW54_RS10620 b972be15d2a5a5287cf2842314a2b0b1 114 SUPERFAMILY SSF69118 9 103 1.14E-26 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CDW54_RS08760 3c93ac7d5b107e21fcc9fb43896da5ba 237 TIGRFAM TIGR01076 sortase_fam: sortase 92 215 9.2E-23 T 28-03-2018 IPR005754 Sortase family CDW54_RS08760 3c93ac7d5b107e21fcc9fb43896da5ba 237 Gene3D G3DSA:2.40.260.10 28 231 5.0E-34 T 28-03-2018 IPR023365 Sortase domain CDW54_RS08760 3c93ac7d5b107e21fcc9fb43896da5ba 237 Pfam PF04203 Sortase family 93 213 3.0E-25 T 28-03-2018 IPR005754 Sortase family CDW54_RS08760 3c93ac7d5b107e21fcc9fb43896da5ba 237 SUPERFAMILY SSF63817 24 214 1.31E-39 T 28-03-2018 IPR023365 Sortase domain CDW54_RS12090 e29fd6ddc81ce99fab02acf3c083aca0 130 Pfam PF14478 Domain of unknown function (DUF4430) 63 128 5.5E-15 T 28-03-2018 IPR027954 Domain of unknown function DUF4430 Reactome: R-HSA-196741 CDW54_RS03885 2127d7b9e408820048ea7cd02dc5401a 167 Pfam PF06177 QueT transporter 13 158 8.2E-33 T 28-03-2018 IPR010387 Queuosine precursor transporter QueT GO:0005886 CDW54_RS03885 2127d7b9e408820048ea7cd02dc5401a 167 PIRSF PIRSF031501 1 167 1.6E-56 T 28-03-2018 IPR010387 Queuosine precursor transporter QueT GO:0005886 CDW54_RS09870 bf2b0d27b6d1eb3997ba692e204a1472 368 Pfam PF00557 Metallopeptidase family M24 149 349 2.4E-61 T 28-03-2018 IPR000994 Peptidase M24 CDW54_RS09870 bf2b0d27b6d1eb3997ba692e204a1472 368 Gene3D G3DSA:3.90.230.10 139 366 4.8E-74 T 28-03-2018 CDW54_RS09870 bf2b0d27b6d1eb3997ba692e204a1472 368 PRINTS PR00599 Methionine aminopeptidase-1 signature 318 330 1.8E-5 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CDW54_RS09870 bf2b0d27b6d1eb3997ba692e204a1472 368 PRINTS PR00599 Methionine aminopeptidase-1 signature 220 236 1.8E-5 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CDW54_RS09870 bf2b0d27b6d1eb3997ba692e204a1472 368 PRINTS PR00599 Methionine aminopeptidase-1 signature 198 211 1.8E-5 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CDW54_RS09870 bf2b0d27b6d1eb3997ba692e204a1472 368 Gene3D G3DSA:3.40.350.10 3 137 9.5E-23 T 28-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CDW54_RS09870 bf2b0d27b6d1eb3997ba692e204a1472 368 SUPERFAMILY SSF55920 139 366 2.36E-77 T 28-03-2018 IPR000994 Peptidase M24 CDW54_RS09870 bf2b0d27b6d1eb3997ba692e204a1472 368 SUPERFAMILY SSF53092 5 137 5.23E-29 T 28-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal CDW54_RS09870 bf2b0d27b6d1eb3997ba692e204a1472 368 Pfam PF01321 Creatinase/Prolidase N-terminal domain 6 139 1.1E-21 T 28-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 CDW54_RS11615 2b9761453fa09932c7d03ed8244cc8e1 137 Gene3D G3DSA:2.60.40.790 2 137 1.2E-33 T 28-03-2018 IPR008978 HSP20-like chaperone CDW54_RS11615 2b9761453fa09932c7d03ed8244cc8e1 137 Pfam PF00011 Hsp20/alpha crystallin family 35 136 1.2E-24 T 28-03-2018 IPR002068 Alpha crystallin/Hsp20 domain CDW54_RS11615 2b9761453fa09932c7d03ed8244cc8e1 137 SUPERFAMILY SSF49764 9 136 5.23E-35 T 28-03-2018 IPR008978 HSP20-like chaperone CDW54_RS03200 c4fbafdf2bff4dd09a93f5393e8fff06 319 Pfam PF12323 Helix-turn-helix domain 1 45 3.5E-20 T 28-03-2018 IPR021027 Transposase, putative, helix-turn-helix domain CDW54_RS01525 c0134f5d0daa6ac634506d0dc4181a18 261 Gene3D G3DSA:3.90.226.10 3 258 3.5E-62 T 28-03-2018 CDW54_RS01525 c0134f5d0daa6ac634506d0dc4181a18 261 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 145 154 6.2E-42 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CDW54_RS01525 c0134f5d0daa6ac634506d0dc4181a18 261 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 101 114 6.2E-42 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CDW54_RS01525 c0134f5d0daa6ac634506d0dc4181a18 261 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 82 98 6.2E-42 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CDW54_RS01525 c0134f5d0daa6ac634506d0dc4181a18 261 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 61 79 6.2E-42 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CDW54_RS01525 c0134f5d0daa6ac634506d0dc4181a18 261 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 36 47 6.2E-42 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CDW54_RS01525 c0134f5d0daa6ac634506d0dc4181a18 261 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 117 130 6.2E-42 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CDW54_RS01525 c0134f5d0daa6ac634506d0dc4181a18 261 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 4 261 3.9E-112 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CDW54_RS01525 c0134f5d0daa6ac634506d0dc4181a18 261 SUPERFAMILY SSF52096 4 260 8.25E-86 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CDW54_RS01525 c0134f5d0daa6ac634506d0dc4181a18 261 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 1 261 36.048 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CDW54_RS01525 c0134f5d0daa6ac634506d0dc4181a18 261 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 4 96 3.2E-42 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CDW54_RS01820 fe762e49bb2d5c77446662960e411ab5 290 Pfam PF04991 LicD family 26 248 1.1E-53 T 28-03-2018 IPR007074 LicD family CDW54_RS00470 4dd856ec399809fd3cf46bbf864ed91a 285 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 278 5.7E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS00470 4dd856ec399809fd3cf46bbf864ed91a 285 SUPERFAMILY SSF161098 2 285 5.89E-66 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS00470 4dd856ec399809fd3cf46bbf864ed91a 285 Gene3D G3DSA:1.10.3720.10 1 272 1.7E-41 T 28-03-2018 CDW54_RS07825 4253283de3eaca11b9d67ea40fe8df3c 227 Pfam PF06912 Protein of unknown function (DUF1275) 12 210 2.3E-37 T 28-03-2018 IPR010699 Protein of unknown function DUF1275 CDW54_RS04155 45e58a1153df9a3fbdcc387c232e24ef 123 Pfam PF15980 Putative Competence protein ComGF 17 112 2.2E-23 T 28-03-2018 IPR016977 Competence operon G, ComGF CDW54_RS04870 909ec400df0317336d933ab0c9cc4aa1 212 Gene3D G3DSA:2.60.120.320 116 212 3.9E-9 T 28-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CDW54_RS04870 909ec400df0317336d933ab0c9cc4aa1 212 TIGRFAM TIGR01378 thi_PPkinase: thiamine pyrophosphokinase 4 208 1.7E-51 T 28-03-2018 IPR006282 Thiamin pyrophosphokinase GO:0004788|GO:0006772 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CDW54_RS04870 909ec400df0317336d933ab0c9cc4aa1 212 Pfam PF04265 Thiamin pyrophosphokinase, vitamin B1 binding domain 144 205 2.7E-11 T 28-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CDW54_RS04870 909ec400df0317336d933ab0c9cc4aa1 212 Gene3D G3DSA:3.40.50.10240 1 115 1.5E-22 T 28-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CDW54_RS04870 909ec400df0317336d933ab0c9cc4aa1 212 Pfam PF04263 Thiamin pyrophosphokinase, catalytic domain 16 116 2.3E-17 T 28-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CDW54_RS04870 909ec400df0317336d933ab0c9cc4aa1 212 SMART SM00983 142 206 1.8E-14 T 28-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CDW54_RS04870 909ec400df0317336d933ab0c9cc4aa1 212 SUPERFAMILY SSF63999 3 131 1.96E-33 T 28-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CDW54_RS04875 a05d99b4b5272b61c88d8133765adb53 216 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 132 154 - T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CDW54_RS04875 a05d99b4b5272b61c88d8133765adb53 216 Gene3D G3DSA:3.20.20.70 1 216 1.6E-86 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDW54_RS04875 a05d99b4b5272b61c88d8133765adb53 216 SUPERFAMILY SSF51366 1 213 1.18E-78 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CDW54_RS04875 a05d99b4b5272b61c88d8133765adb53 216 Pfam PF00834 Ribulose-phosphate 3 epimerase family 2 199 6.4E-81 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CDW54_RS04875 a05d99b4b5272b61c88d8133765adb53 216 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 30 44 - T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CDW54_RS04875 a05d99b4b5272b61c88d8133765adb53 216 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 2 212 1.4E-89 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CDW54_RS04875 a05d99b4b5272b61c88d8133765adb53 216 PIRSF PIRSF001461 1 216 5.1E-91 T 28-03-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CDW54_RS10845 4f66859450e609359b029a29954e700d 266 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 225 251 - T 28-03-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 CDW54_RS10845 4f66859450e609359b029a29954e700d 266 Pfam PF01148 Cytidylyltransferase family 2 263 7.3E-67 T 28-03-2018 CDW54_RS11175 b83d2712994bf1eb9f7f00832ed04c7b 519 Pfam PF02080 TrkA-C domain 441 505 1.9E-10 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CDW54_RS11175 b83d2712994bf1eb9f7f00832ed04c7b 519 Gene3D G3DSA:3.30.70.1450 431 513 3.1E-12 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CDW54_RS11175 b83d2712994bf1eb9f7f00832ed04c7b 519 Gene3D G3DSA:1.10.3080.10 2 430 5.7E-87 T 28-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 CDW54_RS11175 b83d2712994bf1eb9f7f00832ed04c7b 519 Pfam PF00654 Voltage gated chloride channel 70 409 2.3E-88 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CDW54_RS11175 b83d2712994bf1eb9f7f00832ed04c7b 519 PRINTS PR00762 Chloride channel signature 377 396 1.7E-24 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CDW54_RS11175 b83d2712994bf1eb9f7f00832ed04c7b 519 PRINTS PR00762 Chloride channel signature 325 345 1.7E-24 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CDW54_RS11175 b83d2712994bf1eb9f7f00832ed04c7b 519 PRINTS PR00762 Chloride channel signature 82 99 1.7E-24 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CDW54_RS11175 b83d2712994bf1eb9f7f00832ed04c7b 519 PRINTS PR00762 Chloride channel signature 162 181 1.7E-24 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CDW54_RS11175 b83d2712994bf1eb9f7f00832ed04c7b 519 SUPERFAMILY SSF81340 9 424 1.44E-105 T 28-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 CDW54_RS11175 b83d2712994bf1eb9f7f00832ed04c7b 519 SUPERFAMILY SSF116726 434 504 7.59E-12 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CDW54_RS06825 bf13d5097dbb21d27958ed9e06b32801 106 Gene3D G3DSA:3.40.30.10 68 106 0.0022 T 28-03-2018 CDW54_RS06825 bf13d5097dbb21d27958ed9e06b32801 106 SUPERFAMILY SSF52833 14 102 6.46E-23 T 28-03-2018 IPR012336 Thioredoxin-like fold CDW54_RS06825 bf13d5097dbb21d27958ed9e06b32801 106 Pfam PF00085 Thioredoxin 19 101 3.1E-16 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 CDW54_RS06825 bf13d5097dbb21d27958ed9e06b32801 106 Gene3D G3DSA:3.40.30.10 5 67 3.9E-14 T 28-03-2018 CDW54_RS04555 f5ddfe75f73613d3a9ba864fbe59877e 517 Gene3D G3DSA:2.130.10.10 177 513 6.5E-20 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CDW54_RS04555 f5ddfe75f73613d3a9ba864fbe59877e 517 Pfam PF02012 BNR/Asp-box repeat 495 505 0.11 T 28-03-2018 IPR002860 BNR repeat CDW54_RS04555 f5ddfe75f73613d3a9ba864fbe59877e 517 SUPERFAMILY SSF110296 273 509 2.62E-23 T 28-03-2018 CDW54_RS02905 75956722bc0e4690ae9eb5ceb2632e12 126 SMART SM00316 4 75 1.7E-24 T 28-03-2018 IPR022967 RNA-binding domain, S1 CDW54_RS02905 75956722bc0e4690ae9eb5ceb2632e12 126 SUPERFAMILY SSF50249 2 77 5.79E-22 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDW54_RS02905 75956722bc0e4690ae9eb5ceb2632e12 126 Gene3D G3DSA:2.40.50.140 1 83 8.3E-27 T 28-03-2018 CDW54_RS02905 75956722bc0e4690ae9eb5ceb2632e12 126 Pfam PF00575 S1 RNA binding domain 4 75 1.1E-18 T 28-03-2018 IPR003029 S1 domain GO:0003676 CDW54_RS02735 575adb8e302185dda8fc4d06f3579d87 290 ProSitePatterns PS01125 ROK family signature. 131 156 - T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CDW54_RS02735 575adb8e302185dda8fc4d06f3579d87 290 Gene3D G3DSA:3.30.420.40 117 290 1.9E-38 T 28-03-2018 CDW54_RS02735 575adb8e302185dda8fc4d06f3579d87 290 Gene3D G3DSA:3.30.420.40 2 116 6.1E-21 T 28-03-2018 CDW54_RS02735 575adb8e302185dda8fc4d06f3579d87 290 SUPERFAMILY SSF53067 1 286 2.28E-53 T 28-03-2018 CDW54_RS02735 575adb8e302185dda8fc4d06f3579d87 290 Pfam PF00480 ROK family 3 285 2.2E-78 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CDW54_RS01900 7a16187b123acc29757f359ea90a7ec9 379 ProSitePatterns PS01348 MraY family signature 2. 153 164 - T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CDW54_RS01900 7a16187b123acc29757f359ea90a7ec9 379 Pfam PF00953 Glycosyl transferase family 4 80 235 2.9E-39 T 28-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CDW54_RS09480 2a322aa9bad48c3484234c115e655a7c 464 Gene3D G3DSA:3.40.640.10 119 383 4.5E-31 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDW54_RS09480 2a322aa9bad48c3484234c115e655a7c 464 SMART SM00345 28 87 1.0E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDW54_RS09480 2a322aa9bad48c3484234c115e655a7c 464 Pfam PF00155 Aminotransferase class I and II 138 448 1.7E-18 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CDW54_RS09480 2a322aa9bad48c3484234c115e655a7c 464 SUPERFAMILY SSF46785 21 90 1.45E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS09480 2a322aa9bad48c3484234c115e655a7c 464 Pfam PF00392 Bacterial regulatory proteins, gntR family 25 87 3.0E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDW54_RS09480 2a322aa9bad48c3484234c115e655a7c 464 Gene3D G3DSA:1.10.10.10 5 89 8.8E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS09480 2a322aa9bad48c3484234c115e655a7c 464 SUPERFAMILY SSF53383 127 462 2.11E-52 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDW54_RS01115 0979db63e464e4e46fa96be31c0a11f4 151 Gene3D G3DSA:3.40.30.10 1 130 2.1E-18 T 28-03-2018 CDW54_RS01115 0979db63e464e4e46fa96be31c0a11f4 151 SUPERFAMILY SSF52833 13 133 5.26E-21 T 28-03-2018 IPR012336 Thioredoxin-like fold CDW54_RS01115 0979db63e464e4e46fa96be31c0a11f4 151 Pfam PF03960 ArsC family 34 111 8.2E-16 T 28-03-2018 IPR006660 Arsenate reductase-like CDW54_RS01115 0979db63e464e4e46fa96be31c0a11f4 151 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 10 114 1.7E-22 T 28-03-2018 IPR006504 Transcriptional regulator Spx/MgsR CDW54_RS01850 4be038f740d2b3c2531009e06f4266c9 268 Pfam PF01061 ABC-2 type transporter 25 226 3.0E-20 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CDW54_RS02925 16fa3ecc3374482ff0b20db286672c71 169 Gene3D G3DSA:1.10.3760.10 1 169 2.0E-61 T 28-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 CDW54_RS02925 16fa3ecc3374482ff0b20db286672c71 169 SUPERFAMILY SSF101307 9 159 1.44E-53 T 28-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 CDW54_RS02925 16fa3ecc3374482ff0b20db286672c71 169 PIRSF PIRSF019587 3 166 1.4E-75 T 28-03-2018 IPR026038 Putative phosphatidylglycerophosphatase CDW54_RS02925 16fa3ecc3374482ff0b20db286672c71 169 Pfam PF04608 Phosphatidylglycerophosphatase A 15 157 2.5E-20 T 28-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 CDW54_RS00790 8bbcaea980a245c284171f5feb93908b 132 SUPERFAMILY SSF54593 4 131 1.07E-19 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDW54_RS00790 8bbcaea980a245c284171f5feb93908b 132 Gene3D G3DSA:3.10.180.10 1 131 4.7E-14 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDW54_RS00790 8bbcaea980a245c284171f5feb93908b 132 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 126 4.9E-7 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CDW54_RS08030 804cd65d1178190fa0541467f2e6d923 202 Gene3D G3DSA:3.10.350.10 26 108 3.7E-15 T 28-03-2018 CDW54_RS08030 804cd65d1178190fa0541467f2e6d923 202 Pfam PF01476 LysM domain 33 79 4.3E-11 T 28-03-2018 IPR018392 LysM domain CDW54_RS08030 804cd65d1178190fa0541467f2e6d923 202 SMART SM00257 32 79 2.0E-11 T 28-03-2018 IPR018392 LysM domain CDW54_RS08030 804cd65d1178190fa0541467f2e6d923 202 SUPERFAMILY SSF54106 32 79 7.98E-8 T 28-03-2018 IPR018392 LysM domain CDW54_RS07015 06bcb3dea4eecbc52d9282a087524e6e 75 Pfam PF00403 Heavy-metal-associated domain 7 66 2.2E-10 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CDW54_RS07015 06bcb3dea4eecbc52d9282a087524e6e 75 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 37 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CDW54_RS07015 06bcb3dea4eecbc52d9282a087524e6e 75 Gene3D G3DSA:3.30.70.100 1 75 2.5E-16 T 28-03-2018 CDW54_RS07015 06bcb3dea4eecbc52d9282a087524e6e 75 SUPERFAMILY SSF55008 1 69 9.29E-16 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CDW54_RS09315 362d62638517d9eba76de0d30105a510 347 Pfam PF11797 Protein of unknown function C-terminal (DUF3324) 169 304 2.1E-34 T 28-03-2018 IPR021759 Domain of unknown function DUF3324, C-terminal CDW54_RS09315 362d62638517d9eba76de0d30105a510 347 Pfam PF06030 Bacterial protein of unknown function (DUF916) 38 157 8.2E-36 T 28-03-2018 IPR010317 Protein of unknown function DUF916, cell surface putative CDW54_RS09315 362d62638517d9eba76de0d30105a510 347 Gene3D G3DSA:2.60.40.1710 47 168 2.3E-8 T 28-03-2018 CDW54_RS09315 362d62638517d9eba76de0d30105a510 347 Gene3D G3DSA:2.60.40.10 193 303 0.049 T 28-03-2018 IPR013783 Immunoglobulin-like fold CDW54_RS05055 71504449b842258cd3acb8956be9e159 148 Pfam PF13673 Acetyltransferase (GNAT) domain 21 144 1.1E-18 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CDW54_RS05055 71504449b842258cd3acb8956be9e159 148 Gene3D G3DSA:3.40.630.30 1 146 1.6E-24 T 28-03-2018 CDW54_RS05055 71504449b842258cd3acb8956be9e159 148 SUPERFAMILY SSF55729 6 144 3.37E-31 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDW54_RS02815 78ebac7c6532cf0edcfc5f6cb06f6991 209 Pfam PF11193 Protein of unknown function (DUF2812) 10 119 1.1E-16 T 28-03-2018 IPR021359 Protein of unknown function DUF2812 CDW54_RS03240 c019f722d2ae013ea65dcbd1238debd1 182 SUPERFAMILY SSF55729 1 176 1.0E-22 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDW54_RS03240 c019f722d2ae013ea65dcbd1238debd1 182 Gene3D G3DSA:3.40.630.30 1 180 3.3E-26 T 28-03-2018 CDW54_RS03240 c019f722d2ae013ea65dcbd1238debd1 182 Pfam PF00583 Acetyltransferase (GNAT) family 16 117 3.4E-14 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CDW54_RS05675 4a963711aeb90b1567f76b479611e4fe 376 PIRSF PIRSF000804 1 376 4.8E-110 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDW54_RS05675 4a963711aeb90b1567f76b479611e4fe 376 SMART SM00480 17 371 1.9E-130 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDW54_RS05675 4a963711aeb90b1567f76b479611e4fe 376 Gene3D G3DSA:3.10.150.10 1 127 2.3E-27 T 28-03-2018 CDW54_RS05675 4a963711aeb90b1567f76b479611e4fe 376 SUPERFAMILY SSF55979 131 249 2.13E-27 T 28-03-2018 CDW54_RS05675 4a963711aeb90b1567f76b479611e4fe 376 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 252 373 5.3E-25 T 28-03-2018 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDW54_RS05675 4a963711aeb90b1567f76b479611e4fe 376 Gene3D G3DSA:3.10.150.10 128 254 3.3E-32 T 28-03-2018 CDW54_RS05675 4a963711aeb90b1567f76b479611e4fe 376 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 375 2.8E-101 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDW54_RS05675 4a963711aeb90b1567f76b479611e4fe 376 Pfam PF02767 DNA polymerase III beta subunit, central domain 136 249 7.8E-33 T 28-03-2018 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDW54_RS05675 4a963711aeb90b1567f76b479611e4fe 376 SUPERFAMILY SSF55979 251 375 1.1E-26 T 28-03-2018 CDW54_RS05675 4a963711aeb90b1567f76b479611e4fe 376 Gene3D G3DSA:3.10.150.10 255 376 6.9E-21 T 28-03-2018 CDW54_RS05675 4a963711aeb90b1567f76b479611e4fe 376 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 126 3.5E-31 T 28-03-2018 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDW54_RS05675 4a963711aeb90b1567f76b479611e4fe 376 SUPERFAMILY SSF55979 1 126 2.28E-24 T 28-03-2018 CDW54_RS04510 6b613753f71e449e9d47aa41b07f2e23 370 Pfam PF13515 Fusaric acid resistance protein-like 233 350 6.2E-6 T 28-03-2018 CDW54_RS09990 5dd230583999d3d147615eb73a68eeeb 323 SUPERFAMILY SSF52540 112 293 5.68E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS09990 5dd230583999d3d147615eb73a68eeeb 323 Gene3D G3DSA:3.30.1370.10 2 86 4.2E-4 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CDW54_RS09990 5dd230583999d3d147615eb73a68eeeb 323 Pfam PF02562 PhoH-like protein 113 316 1.0E-93 T 28-03-2018 IPR003714 PhoH-like protein GO:0005524 CDW54_RS09990 5dd230583999d3d147615eb73a68eeeb 323 SMART SM00322 4 68 0.0074 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CDW54_RS09990 5dd230583999d3d147615eb73a68eeeb 323 Gene3D G3DSA:3.40.50.300 110 316 4.3E-29 T 28-03-2018 CDW54_RS09990 5dd230583999d3d147615eb73a68eeeb 323 SUPERFAMILY SSF54791 15 67 4.24E-5 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CDW54_RS11300 38889fbba5fb8420a3a51e46e930c733 274 Gene3D G3DSA:3.30.70.260 180 273 1.6E-23 T 28-03-2018 CDW54_RS11300 38889fbba5fb8420a3a51e46e930c733 274 SUPERFAMILY SSF55021 172 269 1.06E-21 T 28-03-2018 CDW54_RS11300 38889fbba5fb8420a3a51e46e930c733 274 Pfam PF00800 Prephenate dehydratase 3 179 1.1E-58 T 28-03-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CDW54_RS11300 38889fbba5fb8420a3a51e46e930c733 274 Gene3D G3DSA:3.40.190.10 1 89 5.0E-28 T 28-03-2018 CDW54_RS11300 38889fbba5fb8420a3a51e46e930c733 274 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 218 225 - T 28-03-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CDW54_RS11300 38889fbba5fb8420a3a51e46e930c733 274 SUPERFAMILY SSF53850 1 181 1.74E-49 T 28-03-2018 CDW54_RS11300 38889fbba5fb8420a3a51e46e930c733 274 Gene3D G3DSA:3.40.190.10 90 166 2.7E-25 T 28-03-2018 CDW54_RS02690 d050be437abfc3007544857f99eada3b 198 Gene3D G3DSA:3.40.50.1390 2 107 2.7E-21 T 28-03-2018 CDW54_RS02690 d050be437abfc3007544857f99eada3b 198 Pfam PF00239 Resolvase, N terminal domain 7 136 5.7E-24 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CDW54_RS02690 d050be437abfc3007544857f99eada3b 198 Gene3D G3DSA:1.10.10.60 137 197 3.6E-12 T 28-03-2018 CDW54_RS02690 d050be437abfc3007544857f99eada3b 198 SMART SM00857 1 136 3.9E-23 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CDW54_RS02690 d050be437abfc3007544857f99eada3b 198 Gene3D G3DSA:1.20.5.40 108 134 3.3E-9 T 28-03-2018 CDW54_RS02690 d050be437abfc3007544857f99eada3b 198 SUPERFAMILY SSF53041 7 136 1.96E-26 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CDW54_RS02690 d050be437abfc3007544857f99eada3b 198 Pfam PF02796 Helix-turn-helix domain of resolvase 138 189 8.0E-14 T 28-03-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 CDW54_RS08150 49ed7e40c0bf54c0e577f108814c98bb 288 SUPERFAMILY SSF103481 37 137 2.48E-7 T 28-03-2018 CDW54_RS08150 49ed7e40c0bf54c0e577f108814c98bb 288 Pfam PF06800 Sugar transport protein 4 284 8.0E-99 T 28-03-2018 IPR010651 Sugar transport protein GO:0015144|GO:0016021|GO:0034219 CDW54_RS08150 49ed7e40c0bf54c0e577f108814c98bb 288 SUPERFAMILY SSF103481 203 283 3.14E-6 T 28-03-2018 CDW54_RS12115 d280d40454a921833616abf92af00087 536 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 373 514 3.4E-15 T 28-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CDW54_RS12115 d280d40454a921833616abf92af00087 536 Pfam PF01943 Polysaccharide biosynthesis protein 5 269 1.7E-18 T 28-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CDW54_RS08810 dddd43ae9e550ee3e66de97a383c9b2e 146 SUPERFAMILY SSF52309 1 145 5.8E-44 T 28-03-2018 CDW54_RS08810 dddd43ae9e550ee3e66de97a383c9b2e 146 Pfam PF05014 Nucleoside 2-deoxyribosyltransferase 4 111 9.0E-22 T 28-03-2018 IPR007710 Nucleoside 2-deoxyribosyltransferase GO:0009159|GO:0050144|GO:0070694 Reactome: R-HSA-74259 CDW54_RS08810 dddd43ae9e550ee3e66de97a383c9b2e 146 Gene3D G3DSA:3.40.50.450 1 146 1.2E-33 T 28-03-2018 CDW54_RS02340 68926689c7187a15de74c48023f89bfa 109 Gene3D G3DSA:3.30.70.120 1 109 5.0E-15 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CDW54_RS02340 68926689c7187a15de74c48023f89bfa 109 SUPERFAMILY SSF54913 1 107 4.67E-13 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta CDW54_RS02340 68926689c7187a15de74c48023f89bfa 109 Pfam PF06153 Cyclic-di-AMP receptor 1 109 4.2E-45 T 28-03-2018 IPR010375 Cyclic-di-AMP receptor CDW54_RS09950 d73aac84b018046397524e9ecf38b577 308 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 289 2.2E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS09950 d73aac84b018046397524e9ecf38b577 308 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 3.0E-38 T 28-03-2018 CDW54_RS09950 d73aac84b018046397524e9ecf38b577 308 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 142 160 3.0E-38 T 28-03-2018 CDW54_RS09950 d73aac84b018046397524e9ecf38b577 308 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 3.0E-38 T 28-03-2018 CDW54_RS09950 d73aac84b018046397524e9ecf38b577 308 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 275 3.0E-38 T 28-03-2018 CDW54_RS09950 d73aac84b018046397524e9ecf38b577 308 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 227 243 3.0E-38 T 28-03-2018 CDW54_RS09950 d73aac84b018046397524e9ecf38b577 308 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 101 109 3.9E-71 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDW54_RS09950 d73aac84b018046397524e9ecf38b577 308 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 229 250 3.9E-71 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDW54_RS09950 d73aac84b018046397524e9ecf38b577 308 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 36 51 3.9E-71 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDW54_RS09950 d73aac84b018046397524e9ecf38b577 308 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 3.9E-71 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDW54_RS09950 d73aac84b018046397524e9ecf38b577 308 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 56 66 3.9E-71 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDW54_RS09950 d73aac84b018046397524e9ecf38b577 308 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 138 162 3.9E-71 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDW54_RS09950 d73aac84b018046397524e9ecf38b577 308 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 263 281 3.9E-71 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDW54_RS09950 d73aac84b018046397524e9ecf38b577 308 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 190 206 3.9E-71 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDW54_RS09950 d73aac84b018046397524e9ecf38b577 308 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 123 135 3.9E-71 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDW54_RS09950 d73aac84b018046397524e9ecf38b577 308 SUPERFAMILY SSF51905 1 300 4.82E-55 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS09950 d73aac84b018046397524e9ecf38b577 308 Gene3D G3DSA:3.50.50.60 1 142 1.4E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS09950 d73aac84b018046397524e9ecf38b577 308 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 2 300 3.2E-117 T 28-03-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 CDW54_RS09950 d73aac84b018046397524e9ecf38b577 308 Gene3D G3DSA:3.50.50.60 254 307 0.003 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS09950 d73aac84b018046397524e9ecf38b577 308 Gene3D G3DSA:3.40.50.720 143 253 1.0E-20 T 28-03-2018 CDW54_RS09950 d73aac84b018046397524e9ecf38b577 308 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 130 150 - T 28-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 CDW54_RS08435 80fdd38b13fe4cd23d808a4a3b0c378e 391 TIGRFAM TIGR01537 portal_HK97: phage portal protein, HK97 family 35 360 2.0E-76 T 28-03-2018 IPR006427 Phage portal protein, HK97 CDW54_RS08435 80fdd38b13fe4cd23d808a4a3b0c378e 391 Pfam PF04860 Phage portal protein 40 354 8.0E-74 T 28-03-2018 IPR006944 Bacteriophage/Gene transfer agent portal protein CDW54_RS11395 8ae1717acd26b636fd80b5c7cc49cf23 156 Pfam PF10263 SprT-like family 7 107 2.7E-10 T 28-03-2018 IPR006640 SprT-like CDW54_RS11395 8ae1717acd26b636fd80b5c7cc49cf23 156 SMART SM00731 4 146 7.9E-42 T 28-03-2018 IPR006640 SprT-like CDW54_RS07935 c3d7dc33e5ec76b0f1f84b8c80269dc1 383 SUPERFAMILY SSF53187 3 184 1.68E-62 T 28-03-2018 CDW54_RS07935 c3d7dc33e5ec76b0f1f84b8c80269dc1 383 SUPERFAMILY SSF53187 282 356 1.68E-62 T 28-03-2018 CDW54_RS07935 c3d7dc33e5ec76b0f1f84b8c80269dc1 383 Pfam PF07687 Peptidase dimerisation domain 174 248 4.3E-5 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CDW54_RS07935 c3d7dc33e5ec76b0f1f84b8c80269dc1 383 PIRSF PIRSF005962 1 363 9.8E-120 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CDW54_RS07935 c3d7dc33e5ec76b0f1f84b8c80269dc1 383 SUPERFAMILY SSF55031 173 276 5.23E-14 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CDW54_RS07935 c3d7dc33e5ec76b0f1f84b8c80269dc1 383 Pfam PF01546 Peptidase family M20/M25/M40 58 356 2.3E-30 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CDW54_RS07935 c3d7dc33e5ec76b0f1f84b8c80269dc1 383 Gene3D G3DSA:3.40.630.10 1 211 1.6E-32 T 28-03-2018 CDW54_RS07935 c3d7dc33e5ec76b0f1f84b8c80269dc1 383 Gene3D G3DSA:3.40.630.10 217 372 1.5E-12 T 28-03-2018 CDW54_RS07935 c3d7dc33e5ec76b0f1f84b8c80269dc1 383 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 4 347 3.5E-75 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CDW54_RS09090 e629950e9e5ae40d2e069509a75b8c4f 306 Gene3D G3DSA:3.30.360.10 128 300 7.2E-17 T 28-03-2018 CDW54_RS09090 e629950e9e5ae40d2e069509a75b8c4f 306 SUPERFAMILY SSF55347 125 260 1.05E-36 T 28-03-2018 CDW54_RS09090 e629950e9e5ae40d2e069509a75b8c4f 306 SUPERFAMILY SSF51735 1 160 3.94E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS09090 e629950e9e5ae40d2e069509a75b8c4f 306 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 120 2.3E-19 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CDW54_RS09090 e629950e9e5ae40d2e069509a75b8c4f 306 Gene3D G3DSA:3.40.50.720 1 127 2.6E-26 T 28-03-2018 CDW54_RS10680 ed57e0aa9807fa4619266616409268b2 318 Gene3D G3DSA:3.40.50.1980 160 318 5.2E-30 T 28-03-2018 CDW54_RS10680 ed57e0aa9807fa4619266616409268b2 318 Pfam PF01497 Periplasmic binding protein 108 294 3.3E-26 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CDW54_RS10680 ed57e0aa9807fa4619266616409268b2 318 SUPERFAMILY SSF53807 46 313 7.85E-52 T 28-03-2018 CDW54_RS10680 ed57e0aa9807fa4619266616409268b2 318 Gene3D G3DSA:3.40.50.1980 31 159 2.0E-22 T 28-03-2018 CDW54_RS10380 2b1ad90d7c3c9c60924a942c7580439e 192 SUPERFAMILY SSF48150 1 185 3.61E-75 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CDW54_RS10380 2b1ad90d7c3c9c60924a942c7580439e 192 Pfam PF03352 Methyladenine glycosylase 5 180 2.1E-77 T 28-03-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 CDW54_RS10380 2b1ad90d7c3c9c60924a942c7580439e 192 Gene3D G3DSA:1.10.340.30 1 181 2.0E-77 T 28-03-2018 CDW54_RS09965 4f1303b6c773bb563da9aab12248293a 286 Gene3D G3DSA:3.40.50.300 19 277 1.6E-6 T 28-03-2018 CDW54_RS09965 4f1303b6c773bb563da9aab12248293a 286 Pfam PF03618 Kinase/pyrophosphorylase 12 266 9.6E-93 T 28-03-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 CDW54_RS09965 4f1303b6c773bb563da9aab12248293a 286 Hamap MF_00921 Putative pyruvate, phosphate dikinase regulatory protein. 9 271 57.603 T 28-03-2018 IPR026565 Putative pyruvate, phosphate dikinase regulatory protein CDW54_RS09965 4f1303b6c773bb563da9aab12248293a 286 SUPERFAMILY SSF52540 22 104 3.63E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS09965 4f1303b6c773bb563da9aab12248293a 286 SUPERFAMILY SSF52540 182 270 3.63E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS06165 6dab0146b2f81d8c8f0cc8194f96ebeb 334 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 293 2.6E-15 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CDW54_RS06165 6dab0146b2f81d8c8f0cc8194f96ebeb 334 SUPERFAMILY SSF52540 6 256 4.58E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS06165 6dab0146b2f81d8c8f0cc8194f96ebeb 334 Pfam PF00005 ABC transporter 27 184 2.1E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS06165 6dab0146b2f81d8c8f0cc8194f96ebeb 334 Gene3D G3DSA:3.40.50.300 3 333 7.0E-81 T 28-03-2018 CDW54_RS06165 6dab0146b2f81d8c8f0cc8194f96ebeb 334 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 235 320 2.0E-20 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CDW54_RS06165 6dab0146b2f81d8c8f0cc8194f96ebeb 334 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS06165 6dab0146b2f81d8c8f0cc8194f96ebeb 334 SMART SM00382 35 234 2.0E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS05880 acb8b96a1fac0a32abbf864688e3c932 228 SMART SM00855 3 189 1.8E-19 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CDW54_RS05880 acb8b96a1fac0a32abbf864688e3c932 228 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 3 228 8.8E-109 T 28-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 CDW54_RS05880 acb8b96a1fac0a32abbf864688e3c932 228 Gene3D G3DSA:3.40.50.1240 1 228 2.0E-58 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CDW54_RS05880 acb8b96a1fac0a32abbf864688e3c932 228 PIRSF PIRSF000709 173 225 3.1 T 28-03-2018 CDW54_RS05880 acb8b96a1fac0a32abbf864688e3c932 228 PIRSF PIRSF000709 2 116 7.3E-7 T 28-03-2018 CDW54_RS05880 acb8b96a1fac0a32abbf864688e3c932 228 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 1 228 43.906 T 28-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 CDW54_RS05880 acb8b96a1fac0a32abbf864688e3c932 228 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 127 2.3E-25 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CDW54_RS05880 acb8b96a1fac0a32abbf864688e3c932 228 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 135 220 1.1E-6 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CDW54_RS05880 acb8b96a1fac0a32abbf864688e3c932 228 SUPERFAMILY SSF53254 1 221 1.84E-71 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CDW54_RS04295 2df2d164877749a26cc47d11efd54425 307 SUPERFAMILY SSF51126 16 286 6.44E-59 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CDW54_RS04295 2df2d164877749a26cc47d11efd54425 307 ProSitePatterns PS00503 Pectinesterase signature 2. 179 188 - T 28-03-2018 IPR033131 Pectinesterase, Asp active site KEGG: 00040+3.1.1.11|MetaCyc: PWY-1081|MetaCyc: PWY-7246|MetaCyc: PWY-7248 CDW54_RS04295 2df2d164877749a26cc47d11efd54425 307 Gene3D G3DSA:2.160.20.10 2 302 1.0E-70 T 28-03-2018 IPR012334 Pectin lyase fold CDW54_RS04295 2df2d164877749a26cc47d11efd54425 307 Pfam PF01095 Pectinesterase 14 145 9.7E-20 T 28-03-2018 IPR000070 Pectinesterase, catalytic GO:0005618|GO:0030599|GO:0042545 KEGG: 00040+3.1.1.11|MetaCyc: PWY-1081|MetaCyc: PWY-7246|MetaCyc: PWY-7248 CDW54_RS04295 2df2d164877749a26cc47d11efd54425 307 Pfam PF01095 Pectinesterase 170 290 5.2E-28 T 28-03-2018 IPR000070 Pectinesterase, catalytic GO:0005618|GO:0030599|GO:0042545 KEGG: 00040+3.1.1.11|MetaCyc: PWY-1081|MetaCyc: PWY-7246|MetaCyc: PWY-7248 CDW54_RS04175 16ef340480f5d7dc8437dc1615414e77 349 Pfam PF00482 Type II secretion system (T2SS), protein F 228 339 2.4E-11 T 28-03-2018 IPR018076 Type II secretion system F domain CDW54_RS04175 16ef340480f5d7dc8437dc1615414e77 349 Pfam PF00482 Type II secretion system (T2SS), protein F 25 144 4.6E-11 T 28-03-2018 IPR018076 Type II secretion system F domain CDW54_RS05170 e222f6bb59d0950603aff947e3bf8d47 209 Pfam PF00881 Nitroreductase family 12 189 5.5E-29 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CDW54_RS05170 e222f6bb59d0950603aff947e3bf8d47 209 Gene3D G3DSA:3.40.109.10 1 209 3.8E-44 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CDW54_RS05170 e222f6bb59d0950603aff947e3bf8d47 209 SUPERFAMILY SSF55469 6 207 1.3E-55 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CDW54_RS07280 c3ec71e70e4a224afd99a4d2cae2189b 206 Gene3D G3DSA:3.40.50.300 1 170 1.3E-18 T 28-03-2018 CDW54_RS07280 c3ec71e70e4a224afd99a4d2cae2189b 206 SUPERFAMILY SSF52540 1 141 3.76E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS07280 c3ec71e70e4a224afd99a4d2cae2189b 206 Pfam PF06414 Zeta toxin 3 129 6.0E-10 T 28-03-2018 IPR010488 Zeta toxin domain GO:0005524|GO:0016301 CDW54_RS05555 0ff4e4943f361e870be21448ca3df90a 231 Gene3D G3DSA:1.10.1900.10 11 83 2.6E-7 T 28-03-2018 CDW54_RS05555 0ff4e4943f361e870be21448ca3df90a 231 SUPERFAMILY SSF158560 8 72 1.83E-6 T 28-03-2018 CDW54_RS05555 0ff4e4943f361e870be21448ca3df90a 231 PIRSF PIRSF033111 3 231 2.5E-76 T 28-03-2018 IPR009214 Protein of unknown function DUF1129 CDW54_RS05555 0ff4e4943f361e870be21448ca3df90a 231 Pfam PF06570 Protein of unknown function (DUF1129) 19 224 1.4E-75 T 28-03-2018 IPR009214 Protein of unknown function DUF1129 CDW54_RS07460 0c376ce737c3ad910959e3e12b030198 289 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 256 289 1.7E-4 T 28-03-2018 CDW54_RS07460 0c376ce737c3ad910959e3e12b030198 289 Gene3D G3DSA:1.20.5.50 131 268 5.4E-4 T 28-03-2018 CDW54_RS07460 0c376ce737c3ad910959e3e12b030198 289 Gene3D G3DSA:1.20.5.50 64 130 0.036 T 28-03-2018 CDW54_RS05585 e157c016f8aea9fcd882b8b3fa15838f 561 Pfam PF09848 Uncharacterized conserved protein (DUF2075) 196 548 5.7E-43 T 28-03-2018 IPR018647 Domain of unknown function DUF2075 CDW54_RS05585 e157c016f8aea9fcd882b8b3fa15838f 561 Pfam PF01541 GIY-YIG catalytic domain 40 103 7.1E-8 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CDW54_RS05585 e157c016f8aea9fcd882b8b3fa15838f 561 Gene3D G3DSA:3.40.1440.10 24 116 3.4E-8 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CDW54_RS05585 e157c016f8aea9fcd882b8b3fa15838f 561 SUPERFAMILY SSF52540 173 338 6.83E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS05585 e157c016f8aea9fcd882b8b3fa15838f 561 SUPERFAMILY SSF52540 28 91 6.83E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS05585 e157c016f8aea9fcd882b8b3fa15838f 561 Gene3D G3DSA:3.40.50.300 138 398 5.0E-14 T 28-03-2018 CDW54_RS09485 d62771962fbb50c0869d7464a05fea94 323 Gene3D G3DSA:3.40.50.720 139 301 3.1E-25 T 28-03-2018 CDW54_RS09485 d62771962fbb50c0869d7464a05fea94 323 PIRSF PIRSF001439 1 322 5.2E-92 T 28-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CDW54_RS09485 d62771962fbb50c0869d7464a05fea94 323 Gene3D G3DSA:3.30.1780.10 1 138 1.0E-39 T 28-03-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 CDW54_RS09485 d62771962fbb50c0869d7464a05fea94 323 SUPERFAMILY SSF51735 1 319 1.87E-86 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS09485 d62771962fbb50c0869d7464a05fea94 323 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 4 319 9.5E-75 T 28-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CDW54_RS07065 622b6c5b50347ebe2904b452886b47ee 277 Gene3D G3DSA:3.30.1060.10 94 265 2.3E-63 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CDW54_RS07065 622b6c5b50347ebe2904b452886b47ee 277 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 95 254 35.621 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CDW54_RS07065 622b6c5b50347ebe2904b452886b47ee 277 Pfam PF01625 Peptide methionine sulfoxide reductase 98 248 2.5E-59 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CDW54_RS07065 622b6c5b50347ebe2904b452886b47ee 277 SUPERFAMILY SSF55068 91 252 6.93E-68 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CDW54_RS07065 622b6c5b50347ebe2904b452886b47ee 277 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 96 247 7.7E-57 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CDW54_RS07065 622b6c5b50347ebe2904b452886b47ee 277 Pfam PF08951 Enterocin A Immunity 5 72 1.0E-18 T 28-03-2018 IPR015046 Enterocin A Immunity CDW54_RS04235 fa16e3f6118898d9fa30417afe469f7e 406 Pfam PF00149 Calcineurin-like phosphoesterase 3 200 1.4E-16 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CDW54_RS04235 fa16e3f6118898d9fa30417afe469f7e 406 SUPERFAMILY SSF56300 1 294 1.47E-47 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CDW54_RS04235 fa16e3f6118898d9fa30417afe469f7e 406 Gene3D G3DSA:3.60.21.10 82 248 3.0E-21 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CDW54_RS04235 fa16e3f6118898d9fa30417afe469f7e 406 Gene3D G3DSA:3.60.21.10 1 81 1.9E-11 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CDW54_RS04235 fa16e3f6118898d9fa30417afe469f7e 406 PIRSF PIRSF033091 1 406 1.7E-108 T 28-03-2018 IPR014576 Predicted phosphoesterase, YhaO type CDW54_RS05740 727f6f555706065e0a3cfaf2ec82beef 287 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 281 1.1E-74 T 28-03-2018 IPR003797 DegV CDW54_RS05740 727f6f555706065e0a3cfaf2ec82beef 287 SUPERFAMILY SSF82549 3 282 2.88E-83 T 28-03-2018 CDW54_RS05740 727f6f555706065e0a3cfaf2ec82beef 287 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 3 282 5.0E-86 T 28-03-2018 IPR003797 DegV CDW54_RS05740 727f6f555706065e0a3cfaf2ec82beef 287 Gene3D G3DSA:3.30.1180.10 158 283 5.2E-38 T 28-03-2018 CDW54_RS05740 727f6f555706065e0a3cfaf2ec82beef 287 Gene3D G3DSA:3.40.50.10170 1 157 1.8E-43 T 28-03-2018 CDW54_RS09360 bde9e98d19d7cdfca6290fa241e7d31d 304 SMART SM00646 191 299 4.9E-19 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CDW54_RS09360 bde9e98d19d7cdfca6290fa241e7d31d 304 SUPERFAMILY SSF53187 129 303 4.08E-46 T 28-03-2018 CDW54_RS09360 bde9e98d19d7cdfca6290fa241e7d31d 304 PIRSF PIRSF037730 1 304 3.3E-114 T 28-03-2018 IPR017273 Probable cell wall amidase LytH GO:0005576|GO:0016811|GO:0071555 CDW54_RS09360 bde9e98d19d7cdfca6290fa241e7d31d 304 Gene3D G3DSA:3.40.630.40 116 303 8.4E-50 T 28-03-2018 CDW54_RS09360 bde9e98d19d7cdfca6290fa241e7d31d 304 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 131 299 1.8E-43 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CDW54_RS03865 31ee2fc95e5084535ee2b5fa429710a2 181 SUPERFAMILY SSF50104 125 180 4.3E-17 T 28-03-2018 IPR008991 Translation protein SH3-like domain CDW54_RS03865 31ee2fc95e5084535ee2b5fa429710a2 181 SUPERFAMILY SSF82679 5 115 1.7E-38 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CDW54_RS03865 31ee2fc95e5084535ee2b5fa429710a2 181 Pfam PF00467 KOW motif 129 156 1.7E-6 T 28-03-2018 IPR005824 KOW CDW54_RS03865 31ee2fc95e5084535ee2b5fa429710a2 181 SMART SM00739 126 153 2.0E-6 T 28-03-2018 IPR005824 KOW CDW54_RS03865 31ee2fc95e5084535ee2b5fa429710a2 181 Gene3D G3DSA:2.30.30.30 121 180 7.2E-21 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 CDW54_RS03865 31ee2fc95e5084535ee2b5fa429710a2 181 Gene3D G3DSA:3.30.70.940 5 119 2.6E-42 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CDW54_RS03865 31ee2fc95e5084535ee2b5fa429710a2 181 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 8 180 7.9E-61 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CDW54_RS03865 31ee2fc95e5084535ee2b5fa429710a2 181 PRINTS PR00338 Transcription termination factor NUSG signature 138 153 3.4E-14 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CDW54_RS03865 31ee2fc95e5084535ee2b5fa429710a2 181 PRINTS PR00338 Transcription termination factor NUSG signature 156 172 3.4E-14 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CDW54_RS03865 31ee2fc95e5084535ee2b5fa429710a2 181 PRINTS PR00338 Transcription termination factor NUSG signature 60 72 3.4E-14 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CDW54_RS03865 31ee2fc95e5084535ee2b5fa429710a2 181 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 5 180 26.453 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CDW54_RS03865 31ee2fc95e5084535ee2b5fa429710a2 181 SMART SM00738 5 116 5.6E-51 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CDW54_RS03865 31ee2fc95e5084535ee2b5fa429710a2 181 Pfam PF02357 Transcription termination factor nusG 6 113 2.3E-28 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CDW54_RS02365 b50234ae83f2ba15fe48b03d31d57825 415 Gene3D G3DSA:2.20.28.20 350 368 2.2E-5 T 28-03-2018 CDW54_RS02365 b50234ae83f2ba15fe48b03d31d57825 415 Pfam PF13421 SPFH domain-Band 7 family 60 268 1.5E-17 T 28-03-2018 IPR033880 SPFH domain, YdjI-like CDW54_RS02365 b50234ae83f2ba15fe48b03d31d57825 415 Gene3D G3DSA:2.20.70.10 399 413 0.29 T 28-03-2018 CDW54_RS02365 b50234ae83f2ba15fe48b03d31d57825 415 Gene3D G3DSA:2.20.70.10 369 392 0.046 T 28-03-2018 CDW54_RS12655 ef8a5b7bf678a8ceddb08f6c83d292ac 311 Gene3D G3DSA:3.40.50.1820 39 311 1.2E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CDW54_RS12655 ef8a5b7bf678a8ceddb08f6c83d292ac 311 Pfam PF12146 Serine aminopeptidase, S33 89 191 9.7E-13 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CDW54_RS12655 ef8a5b7bf678a8ceddb08f6c83d292ac 311 SUPERFAMILY SSF53474 67 199 4.22E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CDW54_RS12655 ef8a5b7bf678a8ceddb08f6c83d292ac 311 SUPERFAMILY SSF53474 238 309 4.22E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CDW54_RS07020 1b7dc95b491744dcbfb1c1e75b37ce99 180 SUPERFAMILY SSF47240 4 171 3.13E-45 T 28-03-2018 IPR009078 Ferritin-like superfamily CDW54_RS07020 1b7dc95b491744dcbfb1c1e75b37ce99 180 Gene3D G3DSA:1.20.1260.10 1 180 3.0E-23 T 28-03-2018 IPR012347 Ferritin-related CDW54_RS11445 ea78f270a0e4139d75a7181bb02734cf 457 Pfam PF07261 Replication initiation and membrane attachment 316 391 5.9E-15 T 28-03-2018 IPR006343 DnaD domain CDW54_RS11445 ea78f270a0e4139d75a7181bb02734cf 457 Gene3D G3DSA:1.10.10.630 311 388 1.1E-13 T 28-03-2018 IPR034829 DnaD-like domain CDW54_RS03690 700d152394d8d42bdf4a3e360218091b 189 Pfam PF08876 Domain of unknown function (DUF1836) 21 119 1.6E-28 T 28-03-2018 IPR014975 Protein of unknown function DUF1836 CDW54_RS10690 829510f42f1ef53e4a42c92431765f51 329 Gene3D G3DSA:1.10.3470.10 1 329 2.2E-65 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CDW54_RS10690 829510f42f1ef53e4a42c92431765f51 329 SUPERFAMILY SSF81345 4 326 3.66E-75 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CDW54_RS10690 829510f42f1ef53e4a42c92431765f51 329 Pfam PF01032 FecCD transport family 17 326 6.4E-85 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CDW54_RS10595 40e9912ded481877946d15a8f4a5df58 128 TIGRFAM TIGR01655 yxeA_fam: conserved hypothetical protein 1 125 8.7E-10 T 28-03-2018 IPR006542 Protein of unknown function DUF1093 CDW54_RS10595 40e9912ded481877946d15a8f4a5df58 128 Pfam PF06486 Protein of unknown function (DUF1093) 26 113 2.1E-14 T 28-03-2018 IPR006542 Protein of unknown function DUF1093 CDW54_RS10595 40e9912ded481877946d15a8f4a5df58 128 SUPERFAMILY SSF159121 21 126 4.05E-16 T 28-03-2018 IPR006542 Protein of unknown function DUF1093 CDW54_RS05945 10086f8792a1416f3cb0c095a06c7645 115 ProSitePatterns PS00464 Ribosomal protein L22 signature. 88 112 - T 28-03-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS05945 10086f8792a1416f3cb0c095a06c7645 115 Pfam PF00237 Ribosomal protein L22p/L17e 10 112 2.0E-40 T 28-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CDW54_RS05945 10086f8792a1416f3cb0c095a06c7645 115 Gene3D G3DSA:3.90.470.10 2 115 1.1E-48 T 28-03-2018 CDW54_RS05945 10086f8792a1416f3cb0c095a06c7645 115 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 10 112 1.1E-48 T 28-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS05945 10086f8792a1416f3cb0c095a06c7645 115 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 6 115 30.647 T 28-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDW54_RS05945 10086f8792a1416f3cb0c095a06c7645 115 SUPERFAMILY SSF54843 6 115 6.02E-46 T 28-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CDW54_RS00815 fbb932b6905562070e26e21e04a3c55a 75 SUPERFAMILY SSF140652 3 71 3.79E-27 T 28-03-2018 IPR023089 YozE SAM-like domain CDW54_RS00815 fbb932b6905562070e26e21e04a3c55a 75 Gene3D G3DSA:1.10.150.260 4 70 8.7E-24 T 28-03-2018 IPR023089 YozE SAM-like domain CDW54_RS00815 fbb932b6905562070e26e21e04a3c55a 75 Hamap MF_01538 UPF0346 protein . 1 71 22.568 T 28-03-2018 IPR010673 Protein of unknown function UPF0346 CDW54_RS00815 fbb932b6905562070e26e21e04a3c55a 75 PIRSF PIRSF037262 1 73 3.0E-30 T 28-03-2018 IPR010673 Protein of unknown function UPF0346 CDW54_RS00815 fbb932b6905562070e26e21e04a3c55a 75 Pfam PF06855 YozE SAM-like fold 4 70 1.5E-26 T 28-03-2018 IPR023089 YozE SAM-like domain CDW54_RS02215 54d48af592fbf87fd306d038f164b118 543 SUPERFAMILY SSF52091 429 534 6.87E-16 T 28-03-2018 IPR002645 STAS domain CDW54_RS02215 54d48af592fbf87fd306d038f164b118 543 Pfam PF01740 STAS domain 430 512 1.1E-7 T 28-03-2018 IPR002645 STAS domain CDW54_RS02215 54d48af592fbf87fd306d038f164b118 543 Pfam PF00916 Sulfate permease family 21 370 1.3E-75 T 28-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CDW54_RS02215 54d48af592fbf87fd306d038f164b118 543 Gene3D G3DSA:3.30.750.24 425 540 1.3E-15 T 28-03-2018 IPR002645 STAS domain CDW54_RS02960 7d2b0c20eb4aa0b33fdf6d5b3afbe5d6 171 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 15 156 45.102 T 28-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 CDW54_RS02960 7d2b0c20eb4aa0b33fdf6d5b3afbe5d6 171 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 60 97 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CDW54_RS02960 7d2b0c20eb4aa0b33fdf6d5b3afbe5d6 171 SUPERFAMILY SSF53927 10 160 8.7E-52 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CDW54_RS02960 7d2b0c20eb4aa0b33fdf6d5b3afbe5d6 171 Pfam PF14437 MafB19-like deaminase 10 156 1.5E-40 T 28-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 CDW54_RS02960 7d2b0c20eb4aa0b33fdf6d5b3afbe5d6 171 Gene3D G3DSA:3.40.140.10 3 166 8.7E-50 T 28-03-2018 CDW54_RS04330 6f98a08d7f974e4e3a71f3255ff605b0 290 SUPERFAMILY SSF161098 10 290 4.09E-56 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS04330 6f98a08d7f974e4e3a71f3255ff605b0 290 Gene3D G3DSA:1.10.3720.10 11 284 4.7E-36 T 28-03-2018 CDW54_RS04330 6f98a08d7f974e4e3a71f3255ff605b0 290 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 281 1.1E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS03365 59b01ba14b0ec41004e35dda932846b6 194 SUPERFAMILY SSF57716 140 188 2.5E-17 T 28-03-2018 CDW54_RS03365 59b01ba14b0ec41004e35dda932846b6 194 Pfam PF00265 Thymidine kinase 3 184 1.2E-48 T 28-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CDW54_RS03365 59b01ba14b0ec41004e35dda932846b6 194 SUPERFAMILY SSF52540 1 139 7.48E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS03365 59b01ba14b0ec41004e35dda932846b6 194 Gene3D G3DSA:3.30.60.20 140 194 7.0E-20 T 28-03-2018 CDW54_RS03365 59b01ba14b0ec41004e35dda932846b6 194 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 171 184 - T 28-03-2018 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CDW54_RS03365 59b01ba14b0ec41004e35dda932846b6 194 Hamap MF_00124 Thymidine kinase [tdk]. 1 187 33.012 T 28-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CDW54_RS03365 59b01ba14b0ec41004e35dda932846b6 194 Gene3D G3DSA:3.40.50.300 2 139 1.7E-43 T 28-03-2018 CDW54_RS03365 59b01ba14b0ec41004e35dda932846b6 194 PIRSF PIRSF035805 1 194 6.5E-59 T 28-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CDW54_RS01795 4cb65da9e05b54047b0addc3e59ecf38 275 Pfam PF04991 LicD family 24 251 4.8E-46 T 28-03-2018 IPR007074 LicD family CDW54_RS07545 2b8a183766600a301576ac7743bb7028 335 Gene3D G3DSA:2.70.98.10 10 335 1.4E-75 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CDW54_RS07545 2b8a183766600a301576ac7743bb7028 335 SUPERFAMILY SSF74650 14 333 6.91E-83 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CDW54_RS07545 2b8a183766600a301576ac7743bb7028 335 ProSitePatterns PS00545 Aldose 1-epimerase putative active site. 167 176 - T 28-03-2018 IPR018052 Aldose 1-epimerase, conserved site KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 CDW54_RS07545 2b8a183766600a301576ac7743bb7028 335 Pfam PF01263 Aldose 1-epimerase 18 331 2.1E-58 T 28-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 CDW54_RS04580 0adb65d986bd55199af440a53f18b7ab 188 SUPERFAMILY SSF53335 8 185 7.02E-26 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDW54_RS04580 0adb65d986bd55199af440a53f18b7ab 188 Gene3D G3DSA:3.40.50.150 1 188 2.0E-25 T 28-03-2018 CDW54_RS04580 0adb65d986bd55199af440a53f18b7ab 188 Pfam PF06962 Putative rRNA methylase 47 185 1.9E-51 T 28-03-2018 IPR010719 Putative rRNA methylase CDW54_RS01240 f289d1aea70b88fc34ee74d3cb056db4 433 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 12 423 9.4E-108 T 28-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 CDW54_RS01240 f289d1aea70b88fc34ee74d3cb056db4 433 Pfam PF02378 Phosphotransferase system, EIIC 29 349 2.7E-52 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CDW54_RS01240 f289d1aea70b88fc34ee74d3cb056db4 433 PIRSF PIRSF006351 1 431 8.4E-138 T 28-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 CDW54_RS08055 e4d3053d08d098ed2c6e7e12790ed0df 151 Pfam PF02863 Arginine repressor, C-terminal domain 82 147 1.6E-18 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CDW54_RS08055 e4d3053d08d098ed2c6e7e12790ed0df 151 Gene3D G3DSA:3.30.1360.40 75 147 2.3E-19 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CDW54_RS08055 e4d3053d08d098ed2c6e7e12790ed0df 151 SUPERFAMILY SSF46785 1 69 2.97E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS08055 e4d3053d08d098ed2c6e7e12790ed0df 151 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 94 140 2.0E-4 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CDW54_RS08055 e4d3053d08d098ed2c6e7e12790ed0df 151 Pfam PF01316 Arginine repressor, DNA binding domain 1 67 2.5E-24 T 28-03-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 CDW54_RS08055 e4d3053d08d098ed2c6e7e12790ed0df 151 PRINTS PR01467 Bacterial arginine repressor signature 119 134 1.3E-14 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CDW54_RS08055 e4d3053d08d098ed2c6e7e12790ed0df 151 PRINTS PR01467 Bacterial arginine repressor signature 21 34 1.3E-14 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CDW54_RS08055 e4d3053d08d098ed2c6e7e12790ed0df 151 PRINTS PR01467 Bacterial arginine repressor signature 37 52 1.3E-14 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CDW54_RS08055 e4d3053d08d098ed2c6e7e12790ed0df 151 Hamap MF_00173 Arginine repressor [argR]. 1 151 52.065 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CDW54_RS08055 e4d3053d08d098ed2c6e7e12790ed0df 151 SUPERFAMILY SSF55252 81 148 4.97E-15 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CDW54_RS08055 e4d3053d08d098ed2c6e7e12790ed0df 151 TIGRFAM TIGR01529 argR_whole: arginine repressor 4 149 1.0E-38 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CDW54_RS08055 e4d3053d08d098ed2c6e7e12790ed0df 151 Gene3D G3DSA:1.10.10.10 3 66 8.3E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS08140 5ef00a4cbf39a505d3493b44bc80c0e7 224 SUPERFAMILY SSF46894 124 222 1.02E-26 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDW54_RS08140 5ef00a4cbf39a505d3493b44bc80c0e7 224 SMART SM00448 2 112 5.4E-33 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDW54_RS08140 5ef00a4cbf39a505d3493b44bc80c0e7 224 SUPERFAMILY SSF52172 1 126 3.13E-35 T 28-03-2018 IPR011006 CheY-like superfamily CDW54_RS08140 5ef00a4cbf39a505d3493b44bc80c0e7 224 SMART SM00862 148 223 3.0E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDW54_RS08140 5ef00a4cbf39a505d3493b44bc80c0e7 224 Gene3D G3DSA:1.10.10.10 125 223 2.9E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS08140 5ef00a4cbf39a505d3493b44bc80c0e7 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 222 1.7E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDW54_RS08140 5ef00a4cbf39a505d3493b44bc80c0e7 224 Gene3D G3DSA:3.40.50.2300 1 124 4.5E-30 T 28-03-2018 CDW54_RS08140 5ef00a4cbf39a505d3493b44bc80c0e7 224 Pfam PF00072 Response regulator receiver domain 4 113 9.6E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDW54_RS02975 02c51a176b17f43e688c4652e28e502c 456 Pfam PF01189 16S rRNA methyltransferase RsmB/F 103 300 5.1E-47 T 28-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CDW54_RS02975 02c51a176b17f43e688c4652e28e502c 456 Pfam PF13636 RNA-binding PUA-like domain of methyltransferase RsmF 409 454 2.4E-14 T 28-03-2018 IPR027391 rRNA small subunit methyltransferase F, RNA-binding PUA-like domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CDW54_RS02975 02c51a176b17f43e688c4652e28e502c 456 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 8 95 8.2E-20 T 28-03-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 CDW54_RS02975 02c51a176b17f43e688c4652e28e502c 456 Pfam PF17126 RsmF rRNA methyltransferase first C-terminal domain 332 391 1.7E-21 T 28-03-2018 IPR031340 Ribosomal RNA small subunit methyltransferase F, first C-terminal domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CDW54_RS02975 02c51a176b17f43e688c4652e28e502c 456 SUPERFAMILY SSF53335 8 300 1.18E-59 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDW54_RS02975 02c51a176b17f43e688c4652e28e502c 456 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 43 300 1.3E-65 T 28-03-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 CDW54_RS02975 02c51a176b17f43e688c4652e28e502c 456 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 227 243 7.3E-23 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CDW54_RS02975 02c51a176b17f43e688c4652e28e502c 456 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 81 95 7.3E-23 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CDW54_RS02975 02c51a176b17f43e688c4652e28e502c 456 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 110 120 7.3E-23 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CDW54_RS02975 02c51a176b17f43e688c4652e28e502c 456 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 177 189 7.3E-23 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CDW54_RS02975 02c51a176b17f43e688c4652e28e502c 456 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 285 302 7.3E-23 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CDW54_RS02975 02c51a176b17f43e688c4652e28e502c 456 Gene3D G3DSA:3.40.50.150 90 311 8.1E-60 T 28-03-2018 CDW54_RS04860 7d50e7df09971ee02da781df18c862c4 169 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 12 162 1.1E-16 T 28-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 CDW54_RS04860 7d50e7df09971ee02da781df18c862c4 169 Pfam PF04093 rod shape-determining protein MreD 3 167 4.6E-45 T 28-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 CDW54_RS04600 53b809252e18eea9c67a379a6ff0650e 262 Gene3D G3DSA:3.40.50.1820 1 261 5.1E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CDW54_RS04600 53b809252e18eea9c67a379a6ff0650e 262 Pfam PF00756 Putative esterase 10 257 1.5E-21 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 CDW54_RS04600 53b809252e18eea9c67a379a6ff0650e 262 SUPERFAMILY SSF53474 3 259 1.05E-49 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CDW54_RS10035 912fad1244a1278f90ec805bd69e03f4 314 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 88 231 6.5E-51 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CDW54_RS10035 912fad1244a1278f90ec805bd69e03f4 314 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 87 231 1.9E-47 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CDW54_RS01505 1034348b3b68776de528cf6c5154af6e 215 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 30 211 7.2E-59 T 28-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 CDW54_RS01505 1034348b3b68776de528cf6c5154af6e 215 Pfam PF01467 Cytidylyltransferase-like 30 185 2.1E-34 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CDW54_RS01505 1034348b3b68776de528cf6c5154af6e 215 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 28 92 2.6E-8 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CDW54_RS01505 1034348b3b68776de528cf6c5154af6e 215 SUPERFAMILY SSF52374 26 213 1.13E-55 T 28-03-2018 CDW54_RS01505 1034348b3b68776de528cf6c5154af6e 215 Gene3D G3DSA:3.40.50.620 25 213 7.0E-54 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDW54_RS01505 1034348b3b68776de528cf6c5154af6e 215 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 26 212 31.395 T 28-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 CDW54_RS01865 9bb883e90eadc5ece40416fd8f9a0ac3 283 Pfam PF04321 RmlD substrate binding domain 2 278 5.8E-111 T 28-03-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 CDW54_RS01865 9bb883e90eadc5ece40416fd8f9a0ac3 283 Gene3D G3DSA:3.40.50.720 2 197 7.1E-29 T 28-03-2018 CDW54_RS01865 9bb883e90eadc5ece40416fd8f9a0ac3 283 Gene3D G3DSA:3.90.25.10 198 264 2.2E-24 T 28-03-2018 CDW54_RS01865 9bb883e90eadc5ece40416fd8f9a0ac3 283 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 3 277 7.4E-92 T 28-03-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 CDW54_RS01865 9bb883e90eadc5ece40416fd8f9a0ac3 283 SUPERFAMILY SSF51735 2 277 3.63E-89 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS03145 34e31751b125b063265d6d79f76010d9 369 Gene3D G3DSA:3.40.50.300 2 238 5.6E-70 T 28-03-2018 CDW54_RS03145 34e31751b125b063265d6d79f76010d9 369 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS03145 34e31751b125b063265d6d79f76010d9 369 Gene3D G3DSA:2.40.50.100 241 295 1.6E-14 T 28-03-2018 CDW54_RS03145 34e31751b125b063265d6d79f76010d9 369 SUPERFAMILY SSF50331 238 366 1.82E-26 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CDW54_RS03145 34e31751b125b063265d6d79f76010d9 369 Gene3D G3DSA:2.40.50.140 296 351 9.3E-12 T 28-03-2018 CDW54_RS03145 34e31751b125b063265d6d79f76010d9 369 Pfam PF00005 ABC transporter 22 163 7.7E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS03145 34e31751b125b063265d6d79f76010d9 369 Pfam PF08402 TOBE domain 284 358 1.1E-5 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CDW54_RS03145 34e31751b125b063265d6d79f76010d9 369 SUPERFAMILY SSF52540 5 246 3.29E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS03145 34e31751b125b063265d6d79f76010d9 369 SMART SM00382 30 213 6.7E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS09120 f5fb428b46d2ce5a0cad6aff6907bf9d 189 Gene3D G3DSA:3.40.630.30 25 112 5.1E-11 T 28-03-2018 CDW54_RS09120 f5fb428b46d2ce5a0cad6aff6907bf9d 189 Pfam PF00583 Acetyltransferase (GNAT) family 57 162 6.8E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CDW54_RS09120 f5fb428b46d2ce5a0cad6aff6907bf9d 189 SUPERFAMILY SSF55729 10 167 4.53E-23 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDW54_RS09120 f5fb428b46d2ce5a0cad6aff6907bf9d 189 Gene3D G3DSA:3.40.630.30 113 170 6.6E-12 T 28-03-2018 CDW54_RS11295 b6b9d6fa0ccb8cd3a194648ab43ad4ef 169 Hamap MF_00109 Shikimate kinase [aroK]. 1 167 26.531 T 28-03-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CDW54_RS11295 b6b9d6fa0ccb8cd3a194648ab43ad4ef 169 ProSitePatterns PS01128 Shikimate kinase signature. 57 81 - T 28-03-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CDW54_RS11295 b6b9d6fa0ccb8cd3a194648ab43ad4ef 169 SUPERFAMILY SSF52540 3 166 5.58E-27 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS11295 b6b9d6fa0ccb8cd3a194648ab43ad4ef 169 PRINTS PR01100 Shikimate kinase family signature 28 41 3.3E-23 T 28-03-2018 CDW54_RS11295 b6b9d6fa0ccb8cd3a194648ab43ad4ef 169 PRINTS PR01100 Shikimate kinase family signature 4 19 3.3E-23 T 28-03-2018 CDW54_RS11295 b6b9d6fa0ccb8cd3a194648ab43ad4ef 169 PRINTS PR01100 Shikimate kinase family signature 94 111 3.3E-23 T 28-03-2018 CDW54_RS11295 b6b9d6fa0ccb8cd3a194648ab43ad4ef 169 PRINTS PR01100 Shikimate kinase family signature 73 82 3.3E-23 T 28-03-2018 CDW54_RS11295 b6b9d6fa0ccb8cd3a194648ab43ad4ef 169 PRINTS PR01100 Shikimate kinase family signature 56 64 3.3E-23 T 28-03-2018 CDW54_RS11295 b6b9d6fa0ccb8cd3a194648ab43ad4ef 169 Gene3D G3DSA:3.40.50.300 2 169 1.4E-28 T 28-03-2018 CDW54_RS11295 b6b9d6fa0ccb8cd3a194648ab43ad4ef 169 Pfam PF01202 Shikimate kinase 10 166 5.8E-45 T 28-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CDW54_RS09700 bd09296f66bb4ca60dd0a5fac3b7b5c0 70 Pfam PF11184 Protein of unknown function (DUF2969) 1 69 4.8E-20 T 28-03-2018 IPR021351 Protein of unknown function DUF2969 CDW54_RS10695 cdee2fc723995ad521226b48adad21c0 334 SUPERFAMILY SSF81345 3 324 2.35E-73 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CDW54_RS10695 cdee2fc723995ad521226b48adad21c0 334 Gene3D G3DSA:1.10.3470.10 1 334 1.9E-58 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CDW54_RS10695 cdee2fc723995ad521226b48adad21c0 334 Pfam PF01032 FecCD transport family 15 324 1.2E-79 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CDW54_RS09435 3e2b24455510583b54716bbffb3a5595 667 Pfam PF01496 V-type ATPase 116kDa subunit family 44 397 2.2E-14 T 28-03-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CDW54_RS03450 67006575efde56659111d4431cedba9c 567 Gene3D G3DSA:3.40.50.2300 362 465 9.5E-12 T 28-03-2018 CDW54_RS03450 67006575efde56659111d4431cedba9c 567 Gene3D G3DSA:3.40.50.2300 478 565 0.075 T 28-03-2018 CDW54_RS03450 67006575efde56659111d4431cedba9c 567 SUPERFAMILY SSF52794 370 453 9.94E-14 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CDW54_RS03450 67006575efde56659111d4431cedba9c 567 Pfam PF02378 Phosphotransferase system, EIIC 28 285 1.1E-10 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CDW54_RS03450 67006575efde56659111d4431cedba9c 567 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 370 438 1.5E-5 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CDW54_RS00480 dbc698cbd0e6a2fd56900ce28b506ccf 427 Pfam PF13416 Bacterial extracellular solute-binding protein 48 349 1.0E-23 T 28-03-2018 CDW54_RS00480 dbc698cbd0e6a2fd56900ce28b506ccf 427 Gene3D G3DSA:3.40.190.10 19 190 4.6E-32 T 28-03-2018 CDW54_RS00480 dbc698cbd0e6a2fd56900ce28b506ccf 427 Gene3D G3DSA:3.40.190.10 196 372 6.7E-9 T 28-03-2018 CDW54_RS00480 dbc698cbd0e6a2fd56900ce28b506ccf 427 SUPERFAMILY SSF53850 19 426 1.65E-55 T 28-03-2018 CDW54_RS10475 a06b2bb8c5bbaccfdb6b05da3786a1b7 165 SUPERFAMILY SSF55781 4 151 2.98E-34 T 28-03-2018 IPR029016 GAF domain-like CDW54_RS10475 a06b2bb8c5bbaccfdb6b05da3786a1b7 165 Gene3D G3DSA:3.30.450.40 2 153 3.4E-18 T 28-03-2018 IPR029016 GAF domain-like CDW54_RS10475 a06b2bb8c5bbaccfdb6b05da3786a1b7 165 Pfam PF13185 GAF domain 49 145 2.8E-9 T 28-03-2018 IPR003018 GAF domain GO:0005515 CDW54_RS06305 985bafc9310992dddbf12efde5c3762e 537 Pfam PF05043 Mga helix-turn-helix domain 111 190 8.2E-16 T 28-03-2018 IPR007737 Mga helix-turn-helix domain CDW54_RS06305 985bafc9310992dddbf12efde5c3762e 537 Gene3D G3DSA:1.10.10.10 115 181 9.2E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS06305 985bafc9310992dddbf12efde5c3762e 537 Gene3D G3DSA:1.10.10.10 28 103 0.34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS12160 f6ae87e1bc04e252fe65b1070fe89d1a 343 Gene3D G3DSA:1.10.443.10 152 327 3.9E-18 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CDW54_RS12160 f6ae87e1bc04e252fe65b1070fe89d1a 343 SUPERFAMILY SSF56349 22 297 1.15E-18 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CDW54_RS12160 f6ae87e1bc04e252fe65b1070fe89d1a 343 Gene3D G3DSA:1.10.150.130 13 151 2.6E-8 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CDW54_RS12160 f6ae87e1bc04e252fe65b1070fe89d1a 343 Pfam PF00589 Phage integrase family 180 283 4.7E-13 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CDW54_RS05360 3e1b935f713e95c67586e117c1987fbe 322 Gene3D G3DSA:3.40.50.2300 2 178 4.2E-25 T 28-03-2018 CDW54_RS05360 3e1b935f713e95c67586e117c1987fbe 322 Gene3D G3DSA:3.40.50.2300 179 298 3.8E-15 T 28-03-2018 CDW54_RS05360 3e1b935f713e95c67586e117c1987fbe 322 SUPERFAMILY SSF53822 45 294 3.93E-14 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CDW54_RS05360 3e1b935f713e95c67586e117c1987fbe 322 Pfam PF04392 ABC transporter substrate binding protein 35 314 2.2E-87 T 28-03-2018 IPR007487 ABC transporter, substrate-binding protein CDW54_RS06650 2dd24dd384d53ff12e04604a28e78a1a 305 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 32 298 1.5E-49 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CDW54_RS06650 2dd24dd384d53ff12e04604a28e78a1a 305 Gene3D G3DSA:3.40.190.10 181 302 7.1E-22 T 28-03-2018 CDW54_RS06650 2dd24dd384d53ff12e04604a28e78a1a 305 Gene3D G3DSA:3.40.190.10 20 180 1.1E-28 T 28-03-2018 CDW54_RS06650 2dd24dd384d53ff12e04604a28e78a1a 305 SUPERFAMILY SSF53850 32 301 1.42E-62 T 28-03-2018 CDW54_RS11145 9bf4edf3467e3c54695320ba40e4ecfb 195 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 11 193 28.704 T 28-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 CDW54_RS11145 9bf4edf3467e3c54695320ba40e4ecfb 195 Pfam PF01926 50S ribosome-binding GTPase 25 143 1.6E-21 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CDW54_RS11145 9bf4edf3467e3c54695320ba40e4ecfb 195 Gene3D G3DSA:3.40.50.300 2 195 5.5E-31 T 28-03-2018 CDW54_RS11145 9bf4edf3467e3c54695320ba40e4ecfb 195 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 7 189 1.3E-73 T 28-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 CDW54_RS11145 9bf4edf3467e3c54695320ba40e4ecfb 195 SUPERFAMILY SSF52540 1 193 3.69E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS09380 0c65e48469c20f9df518336867a00023 182 Pfam PF02674 Colicin V production protein 2 164 7.8E-30 T 28-03-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 CDW54_RS11820 fe50c1cda73b3e44414f3c3ef79f91d4 157 Pfam PF11188 Protein of unknown function (DUF2975) 38 157 5.2E-19 T 28-03-2018 IPR021354 Protein of unknown function DUF2975 CDW54_RS10575 067a0f1fbea803d319e13ed55452c2ec 161 Pfam PF04073 Aminoacyl-tRNA editing domain 35 148 3.3E-23 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CDW54_RS10575 067a0f1fbea803d319e13ed55452c2ec 161 SUPERFAMILY SSF55826 9 159 3.92E-41 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CDW54_RS10575 067a0f1fbea803d319e13ed55452c2ec 161 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 9 159 1.3E-60 T 28-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC CDW54_RS10575 067a0f1fbea803d319e13ed55452c2ec 161 PIRSF PIRSF006181 4 161 3.7E-65 T 28-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC CDW54_RS10575 067a0f1fbea803d319e13ed55452c2ec 161 Gene3D G3DSA:3.90.960.10 1 161 1.2E-37 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CDW54_RS00350 05e1d523177f7e7382e2f081651d8efe 508 Gene3D G3DSA:3.40.50.300 2 238 9.4E-50 T 28-03-2018 CDW54_RS00350 05e1d523177f7e7382e2f081651d8efe 508 SUPERFAMILY SSF52540 260 493 2.85E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS00350 05e1d523177f7e7382e2f081651d8efe 508 SUPERFAMILY SSF52540 5 227 2.99E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS00350 05e1d523177f7e7382e2f081651d8efe 508 Gene3D G3DSA:3.40.50.300 255 501 1.3E-34 T 28-03-2018 CDW54_RS00350 05e1d523177f7e7382e2f081651d8efe 508 ProSitePatterns PS00211 ABC transporters family signature. 407 421 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS00350 05e1d523177f7e7382e2f081651d8efe 508 SMART SM00382 287 503 0.0029 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS00350 05e1d523177f7e7382e2f081651d8efe 508 SMART SM00382 30 220 2.8E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS00350 05e1d523177f7e7382e2f081651d8efe 508 Pfam PF00005 ABC transporter 279 434 2.6E-18 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS00350 05e1d523177f7e7382e2f081651d8efe 508 Pfam PF00005 ABC transporter 21 172 3.6E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS09195 02aabb93a78c02b76883682d16fae828 376 SUPERFAMILY SSF51726 10 376 2.62E-77 T 28-03-2018 CDW54_RS09195 02aabb93a78c02b76883682d16fae828 376 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 11 81 1.2E-5 T 28-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CDW54_RS09195 02aabb93a78c02b76883682d16fae828 376 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 174 350 2.6E-7 T 28-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CDW54_RS09195 02aabb93a78c02b76883682d16fae828 376 Gene3D G3DSA:3.20.20.210 1 376 8.8E-93 T 28-03-2018 CDW54_RS08725 fbd4dc205762b44064ab53f575c3dfe0 1056 Gene3D G3DSA:2.60.40.1310 709 902 1.7E-5 T 28-03-2018 CDW54_RS02920 b59947dd5c2dc8f644c0773590fe55af 332 Gene3D G3DSA:3.50.50.60 3 142 3.5E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS02920 b59947dd5c2dc8f644c0773590fe55af 332 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 283 5.0E-22 T 28-03-2018 CDW54_RS02920 b59947dd5c2dc8f644c0773590fe55af 332 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 151 169 5.0E-22 T 28-03-2018 CDW54_RS02920 b59947dd5c2dc8f644c0773590fe55af 332 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 5.0E-22 T 28-03-2018 CDW54_RS02920 b59947dd5c2dc8f644c0773590fe55af 332 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 235 251 5.0E-22 T 28-03-2018 CDW54_RS02920 b59947dd5c2dc8f644c0773590fe55af 332 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 5.0E-22 T 28-03-2018 CDW54_RS02920 b59947dd5c2dc8f644c0773590fe55af 332 SUPERFAMILY SSF51905 1 312 4.37E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS02920 b59947dd5c2dc8f644c0773590fe55af 332 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 5 27 1.2E-25 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDW54_RS02920 b59947dd5c2dc8f644c0773590fe55af 332 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 108 116 1.2E-25 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDW54_RS02920 b59947dd5c2dc8f644c0773590fe55af 332 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 147 171 1.2E-25 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDW54_RS02920 b59947dd5c2dc8f644c0773590fe55af 332 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 62 72 1.2E-25 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDW54_RS02920 b59947dd5c2dc8f644c0773590fe55af 332 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 271 289 1.2E-25 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDW54_RS02920 b59947dd5c2dc8f644c0773590fe55af 332 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 292 5.1E-27 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS02920 b59947dd5c2dc8f644c0773590fe55af 332 Gene3D G3DSA:3.40.50.720 144 327 1.5E-18 T 28-03-2018 CDW54_RS02920 b59947dd5c2dc8f644c0773590fe55af 332 Hamap MF_01685 Ferredoxin--NADP reductase. 3 324 43.237 T 28-03-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 CDW54_RS04170 ca3b7d6c62b0a628b56d87c1da74419c 92 SUPERFAMILY SSF54523 12 86 4.79E-13 T 28-03-2018 CDW54_RS04170 ca3b7d6c62b0a628b56d87c1da74419c 92 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 10 30 1.2E-6 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDW54_RS04170 ca3b7d6c62b0a628b56d87c1da74419c 92 PIRSF PIRSF029928 1 92 2.1E-32 T 28-03-2018 IPR016940 ComG operon protein C GO:0030420 CDW54_RS04170 ca3b7d6c62b0a628b56d87c1da74419c 92 Gene3D G3DSA:3.30.700.10 12 82 4.8E-10 T 28-03-2018 CDW54_RS04170 ca3b7d6c62b0a628b56d87c1da74419c 92 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 10 30 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDW54_RS04170 ca3b7d6c62b0a628b56d87c1da74419c 92 PRINTS PR00813 Bacterial general secretion pathway protein G signature 11 36 3.8E-9 T 28-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 CDW54_RS04170 ca3b7d6c62b0a628b56d87c1da74419c 92 PRINTS PR00813 Bacterial general secretion pathway protein G signature 47 65 3.8E-9 T 28-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 CDW54_RS04170 ca3b7d6c62b0a628b56d87c1da74419c 92 Pfam PF07963 Prokaryotic N-terminal methylation motif 9 30 2.6E-7 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDW54_RS00375 1ad96d7ae9488a726f49853f51e6e5d8 304 SUPERFAMILY SSF51430 1 299 1.7E-76 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CDW54_RS00375 1ad96d7ae9488a726f49853f51e6e5d8 304 Pfam PF00248 Aldo/keto reductase family 16 296 1.8E-57 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CDW54_RS00375 1ad96d7ae9488a726f49853f51e6e5d8 304 Gene3D G3DSA:3.20.20.100 1 302 3.3E-74 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CDW54_RS00375 1ad96d7ae9488a726f49853f51e6e5d8 304 PRINTS PR00069 Aldo-keto reductase signature 36 60 4.5E-7 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CDW54_RS00375 1ad96d7ae9488a726f49853f51e6e5d8 304 PRINTS PR00069 Aldo-keto reductase signature 100 118 4.5E-7 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CDW54_RS00375 1ad96d7ae9488a726f49853f51e6e5d8 304 PRINTS PR00069 Aldo-keto reductase signature 131 148 4.5E-7 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CDW54_RS02440 324f76d3bc47d8a788f7484341c08180 423 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 407 3.5E-88 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CDW54_RS02440 324f76d3bc47d8a788f7484341c08180 423 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 415 5.2E-160 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDW54_RS02440 324f76d3bc47d8a788f7484341c08180 423 Gene3D G3DSA:3.65.10.10 21 218 1.1E-42 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CDW54_RS02440 324f76d3bc47d8a788f7484341c08180 423 Gene3D G3DSA:3.65.10.10 219 420 1.8E-49 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CDW54_RS02440 324f76d3bc47d8a788f7484341c08180 423 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 417 41.521 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDW54_RS02440 324f76d3bc47d8a788f7484341c08180 423 SUPERFAMILY SSF55205 1 418 9.65E-135 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CDW54_RS03265 2f172e3cd3288518891e7bf0451ab692 478 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 374 382 - T 28-03-2018 IPR018120 Glycoside hydrolase family 1, active site CDW54_RS03265 2f172e3cd3288518891e7bf0451ab692 478 SUPERFAMILY SSF51445 8 477 4.9E-171 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CDW54_RS03265 2f172e3cd3288518891e7bf0451ab692 478 PRINTS PR00131 Glycosyl hydrolase family 1 signature 440 452 4.8E-18 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS03265 2f172e3cd3288518891e7bf0451ab692 478 PRINTS PR00131 Glycosyl hydrolase family 1 signature 416 433 4.8E-18 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS03265 2f172e3cd3288518891e7bf0451ab692 478 PRINTS PR00131 Glycosyl hydrolase family 1 signature 395 406 4.8E-18 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS03265 2f172e3cd3288518891e7bf0451ab692 478 PRINTS PR00131 Glycosyl hydrolase family 1 signature 292 306 4.8E-18 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS03265 2f172e3cd3288518891e7bf0451ab692 478 PRINTS PR00131 Glycosyl hydrolase family 1 signature 374 382 4.8E-18 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS03265 2f172e3cd3288518891e7bf0451ab692 478 Gene3D G3DSA:3.20.20.80 6 478 3.3E-169 T 28-03-2018 CDW54_RS03265 2f172e3cd3288518891e7bf0451ab692 478 Pfam PF00232 Glycosyl hydrolase family 1 8 475 8.8E-176 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS03265 2f172e3cd3288518891e7bf0451ab692 478 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 13 27 - T 28-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site CDW54_RS03225 eb8ad51fdcac4426b43fb8bce871d525 115 Pfam PF13038 Domain of unknown function (DUF3899) 34 109 2.2E-10 T 28-03-2018 IPR025007 Domain of unknown function DUF3899 CDW54_RS11460 cc6f3f70384f206299631c9a49304998 233 PIRSF PIRSF018637 4 233 6.2E-79 T 28-03-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 CDW54_RS11460 cc6f3f70384f206299631c9a49304998 233 SUPERFAMILY SSF53335 9 141 1.23E-8 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDW54_RS11460 cc6f3f70384f206299631c9a49304998 233 Gene3D G3DSA:3.40.50.150 1 169 5.0E-17 T 28-03-2018 CDW54_RS11460 cc6f3f70384f206299631c9a49304998 233 Pfam PF04816 tRNA (adenine(22)-N(1))-methyltransferase 23 229 7.6E-75 T 28-03-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 CDW54_RS05000 d20af3e7a40bae9f7ae5e64a38bb04bd 857 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 18 298 1.0E-9 T 28-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD CDW54_RS05000 d20af3e7a40bae9f7ae5e64a38bb04bd 857 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 533 822 6.2E-52 T 28-03-2018 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal CDW54_RS03545 e80408b1582f776dbb826ea342e1fcd7 553 SUPERFAMILY SSF53067 277 520 4.14E-14 T 28-03-2018 CDW54_RS03545 e80408b1582f776dbb826ea342e1fcd7 553 SUPERFAMILY SSF53067 19 266 1.87E-29 T 28-03-2018 CDW54_RS03545 e80408b1582f776dbb826ea342e1fcd7 553 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 19 264 1.5E-15 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CDW54_RS03545 e80408b1582f776dbb826ea342e1fcd7 553 Gene3D G3DSA:3.30.420.40 271 525 2.9E-35 T 28-03-2018 CDW54_RS03545 e80408b1582f776dbb826ea342e1fcd7 553 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 279 476 8.7E-34 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CDW54_RS03545 e80408b1582f776dbb826ea342e1fcd7 553 Gene3D G3DSA:3.30.420.40 14 270 1.7E-37 T 28-03-2018 CDW54_RS09960 6f9e4a45f6ba0b3bbce25f75395b78ed 97 SMART SM00418 14 92 3.9E-31 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CDW54_RS09960 6f9e4a45f6ba0b3bbce25f75395b78ed 97 Gene3D G3DSA:1.10.10.10 2 97 7.2E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS09960 6f9e4a45f6ba0b3bbce25f75395b78ed 97 SUPERFAMILY SSF46785 8 95 4.13E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS09960 6f9e4a45f6ba0b3bbce25f75395b78ed 97 Pfam PF01022 Bacterial regulatory protein, arsR family 21 66 2.3E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CDW54_RS09960 6f9e4a45f6ba0b3bbce25f75395b78ed 97 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 48 63 8.3E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CDW54_RS09960 6f9e4a45f6ba0b3bbce25f75395b78ed 97 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 63 78 8.3E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CDW54_RS09960 6f9e4a45f6ba0b3bbce25f75395b78ed 97 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 16 31 8.3E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CDW54_RS08470 5f37dffbed08cb5fa099b038a206d44e 379 Gene3D G3DSA:1.10.443.10 170 366 3.9E-40 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CDW54_RS08470 5f37dffbed08cb5fa099b038a206d44e 379 Pfam PF00589 Phage integrase family 173 364 4.1E-34 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CDW54_RS08470 5f37dffbed08cb5fa099b038a206d44e 379 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 68 124 5.3E-20 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CDW54_RS08470 5f37dffbed08cb5fa099b038a206d44e 379 Gene3D G3DSA:1.10.150.130 67 148 1.2E-12 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CDW54_RS08470 5f37dffbed08cb5fa099b038a206d44e 379 Pfam PF14657 Arm DNA-binding domain 16 58 2.1E-10 T 28-03-2018 IPR028259 AP2-like integrase, N-terminal domain CDW54_RS08470 5f37dffbed08cb5fa099b038a206d44e 379 SUPERFAMILY SSF56349 68 369 3.24E-63 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CDW54_RS12035 b982786808b4268749a9164d99e2ab92 219 SUPERFAMILY SSF161098 17 206 3.79E-37 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS12035 b982786808b4268749a9164d99e2ab92 219 Gene3D G3DSA:1.10.3720.10 12 216 2.0E-31 T 28-03-2018 CDW54_RS12035 b982786808b4268749a9164d99e2ab92 219 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 54 213 1.6E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS12035 b982786808b4268749a9164d99e2ab92 219 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 15 109 1.0E-22 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CDW54_RS00280 a8deedc9dcdb14227fba83194ba8f10b 100 Pfam PF07408 Protein of unknown function (DUF1507) 6 88 4.1E-38 T 28-03-2018 IPR009983 Uncharacterised protein family UPF0358 CDW54_RS00280 a8deedc9dcdb14227fba83194ba8f10b 100 Gene3D G3DSA:1.10.287.750 4 86 3.9E-35 T 28-03-2018 CDW54_RS00280 a8deedc9dcdb14227fba83194ba8f10b 100 SUPERFAMILY SSF140404 5 81 4.84E-32 T 28-03-2018 IPR009983 Uncharacterised protein family UPF0358 CDW54_RS10755 e58c8479cf19c92ca182a78262554710 274 SUPERFAMILY SSF53067 142 235 2.07E-11 T 28-03-2018 CDW54_RS10755 e58c8479cf19c92ca182a78262554710 274 Gene3D G3DSA:3.30.420.40 23 172 2.6E-37 T 28-03-2018 CDW54_RS10755 e58c8479cf19c92ca182a78262554710 274 Pfam PF00814 Glycoprotease family 65 182 1.4E-32 T 28-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CDW54_RS10755 e58c8479cf19c92ca182a78262554710 274 SUPERFAMILY SSF53067 35 135 9.93E-28 T 28-03-2018 CDW54_RS10755 e58c8479cf19c92ca182a78262554710 274 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 38 251 5.7E-50 T 28-03-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 CDW54_RS01245 87be71ac6400bc0f9ad270373c2fc641 152 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 12 127 2.6E-37 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CDW54_RS01245 87be71ac6400bc0f9ad270373c2fc641 152 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 10 127 7.6E-41 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CDW54_RS01245 87be71ac6400bc0f9ad270373c2fc641 152 Gene3D G3DSA:2.70.70.10 4 152 1.6E-43 T 28-03-2018 CDW54_RS01245 87be71ac6400bc0f9ad270373c2fc641 152 SUPERFAMILY SSF51261 4 133 1.92E-41 T 28-03-2018 IPR011055 Duplicated hybrid motif CDW54_RS01245 87be71ac6400bc0f9ad270373c2fc641 152 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 72 84 - T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CDW54_RS04465 12efe01b3291c95a01865ccf21bdb1e7 548 Pfam PF01943 Polysaccharide biosynthesis protein 19 329 1.2E-31 T 28-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CDW54_RS04465 12efe01b3291c95a01865ccf21bdb1e7 548 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 382 529 2.4E-27 T 28-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CDW54_RS04465 12efe01b3291c95a01865ccf21bdb1e7 548 PIRSF PIRSF038958 14 544 1.7E-81 T 28-03-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type CDW54_RS02040 49841796d41e610964eea0e76adadcdf 225 SUPERFAMILY SSF51419 2 222 1.57E-67 T 28-03-2018 IPR029066 PLP-binding barrel CDW54_RS02040 49841796d41e610964eea0e76adadcdf 225 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 2 224 1.4E-54 T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein CDW54_RS02040 49841796d41e610964eea0e76adadcdf 225 PIRSF PIRSF004848 1 225 2.1E-65 T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein CDW54_RS02040 49841796d41e610964eea0e76adadcdf 225 Gene3D G3DSA:3.20.20.10 1 225 3.8E-56 T 28-03-2018 IPR029066 PLP-binding barrel CDW54_RS02040 49841796d41e610964eea0e76adadcdf 225 Pfam PF01168 Alanine racemase, N-terminal domain 6 224 1.7E-19 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CDW54_RS09845 d51db5f586c77efdf72855b5c57b9504 276 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 8 255 8.2E-77 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CDW54_RS09845 d51db5f586c77efdf72855b5c57b9504 276 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 4 259 1.1E-71 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CDW54_RS09845 d51db5f586c77efdf72855b5c57b9504 276 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 133 145 - T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CDW54_RS09845 d51db5f586c77efdf72855b5c57b9504 276 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 4 260 17.696 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CDW54_RS07100 505ec41fb5282be989f706b87179291b 417 Pfam PF02378 Phosphotransferase system, EIIC 29 341 3.4E-51 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CDW54_RS07100 505ec41fb5282be989f706b87179291b 417 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 13 413 1.4E-112 T 28-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 CDW54_RS07100 505ec41fb5282be989f706b87179291b 417 PIRSF PIRSF006351 1 417 4.2E-123 T 28-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 CDW54_RS09930 fddf40e36d7fdfd907156d1a0e635f8e 300 Gene3D G3DSA:3.40.50.10490 84 281 1.1E-19 T 28-03-2018 CDW54_RS09930 fddf40e36d7fdfd907156d1a0e635f8e 300 SUPERFAMILY SSF46689 11 71 5.55E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDW54_RS09930 fddf40e36d7fdfd907156d1a0e635f8e 300 SUPERFAMILY SSF53697 94 266 2.89E-22 T 28-03-2018 CDW54_RS09930 fddf40e36d7fdfd907156d1a0e635f8e 300 Pfam PF01380 SIS domain 128 246 1.1E-13 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CDW54_RS09930 fddf40e36d7fdfd907156d1a0e635f8e 300 Pfam PF01418 Helix-turn-helix domain, rpiR family 10 69 2.9E-10 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CDW54_RS09930 fddf40e36d7fdfd907156d1a0e635f8e 300 Gene3D G3DSA:1.10.10.10 3 74 4.1E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS11765 d79686bc63b7375ab3bea655890a9ef8 300 Gene3D G3DSA:3.90.550.10 6 279 9.9E-56 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDW54_RS11765 d79686bc63b7375ab3bea655890a9ef8 300 Pfam PF01501 Glycosyl transferase family 8 8 257 6.8E-49 T 28-03-2018 IPR002495 Glycosyl transferase, family 8 GO:0016757 CDW54_RS11765 d79686bc63b7375ab3bea655890a9ef8 300 SUPERFAMILY SSF53448 6 274 6.0E-68 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDW54_RS00610 aef4f2a346c5d0001ba4ba7d74b7f829 245 Pfam PF00005 ABC transporter 18 155 3.4E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS00610 aef4f2a346c5d0001ba4ba7d74b7f829 245 Gene3D G3DSA:3.40.50.300 1 236 8.3E-52 T 28-03-2018 CDW54_RS00610 aef4f2a346c5d0001ba4ba7d74b7f829 245 SUPERFAMILY SSF52540 3 215 4.07E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS00610 aef4f2a346c5d0001ba4ba7d74b7f829 245 SMART SM00382 27 204 1.0E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS05410 c055f216a9018582f06dd222b145c036 644 Gene3D G3DSA:3.50.50.60 2 128 9.4E-15 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS05410 c055f216a9018582f06dd222b145c036 644 SUPERFAMILY SSF51905 158 339 2.27E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS05410 c055f216a9018582f06dd222b145c036 644 SUPERFAMILY SSF51905 4 211 8.39E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS05410 c055f216a9018582f06dd222b145c036 644 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 326 2.4E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS05410 c055f216a9018582f06dd222b145c036 644 Gene3D G3DSA:3.50.50.60 129 336 7.8E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS05410 c055f216a9018582f06dd222b145c036 644 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 3.8E-7 T 28-03-2018 CDW54_RS05410 c055f216a9018582f06dd222b145c036 644 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 161 179 3.8E-7 T 28-03-2018 CDW54_RS05410 c055f216a9018582f06dd222b145c036 644 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 3.8E-7 T 28-03-2018 CDW54_RS09260 4f7d657b22d3f204bd439b3c1f60a4cc 88 Pfam PF06135 Bacterial protein of unknown function (DUF965) 5 81 5.0E-36 T 28-03-2018 IPR009309 Uncharacterised protein family UPF0297 CDW54_RS09260 4f7d657b22d3f204bd439b3c1f60a4cc 88 Hamap MF_01507 UPF0297 protein . 1 84 26.897 T 28-03-2018 IPR009309 Uncharacterised protein family UPF0297 CDW54_RS09260 4f7d657b22d3f204bd439b3c1f60a4cc 88 PIRSF PIRSF037258 1 87 1.6E-42 T 28-03-2018 IPR009309 Uncharacterised protein family UPF0297 CDW54_RS02080 abddbe501ff598f4ce59389e8f7ab2ac 133 Pfam PF04977 Septum formation initiator 60 132 6.0E-7 T 28-03-2018 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 CDW54_RS02080 abddbe501ff598f4ce59389e8f7ab2ac 133 SUPERFAMILY SSF58100 41 108 6.54E-5 T 28-03-2018 CDW54_RS02080 abddbe501ff598f4ce59389e8f7ab2ac 133 Hamap MF_00910 Cell division protein FtsL [ftsL]. 51 133 13.475 T 28-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 CDW54_RS02080 abddbe501ff598f4ce59389e8f7ab2ac 133 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 56 131 4.6E-16 T 28-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 CDW54_RS01950 8b1eaae0b220f5540bfe0d427a9d832f 137 Gene3D G3DSA:3.30.530.20 18 136 9.3E-5 T 28-03-2018 IPR023393 START-like domain CDW54_RS01950 8b1eaae0b220f5540bfe0d427a9d832f 137 Pfam PF11687 Domain of unknown function (DUF3284) 1 118 4.5E-41 T 28-03-2018 IPR021701 Protein of unknown function DUF3284 CDW54_RS01950 8b1eaae0b220f5540bfe0d427a9d832f 137 SUPERFAMILY SSF55961 49 103 1.95E-5 T 28-03-2018 CDW54_RS11695 2e74f1f9168930731307a0deb1ced2b9 68 Pfam PF13127 Protein of unknown function (DUF3955) 4 62 3.0E-17 T 28-03-2018 IPR025016 Protein of unknown function DUF3955 CDW54_RS03485 8d7f7d3cf26246f2d4bfe865c26ea5c4 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 60 5.0E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDW54_RS03485 8d7f7d3cf26246f2d4bfe865c26ea5c4 216 Gene3D G3DSA:1.10.10.60 49 156 4.9E-7 T 28-03-2018 CDW54_RS03485 8d7f7d3cf26246f2d4bfe865c26ea5c4 216 Gene3D G3DSA:1.10.10.60 11 48 3.4E-10 T 28-03-2018 CDW54_RS03485 8d7f7d3cf26246f2d4bfe865c26ea5c4 216 SUPERFAMILY SSF46689 12 70 2.57E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDW54_RS03230 5a350b9809126dca127fb2c622496585 554 Gene3D G3DSA:3.40.190.10 208 308 2.0E-18 T 28-03-2018 CDW54_RS03230 5a350b9809126dca127fb2c622496585 554 PIRSF PIRSF002741 1 554 1.3E-98 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CDW54_RS03230 5a350b9809126dca127fb2c622496585 554 Gene3D G3DSA:3.90.76.10 73 205 3.9E-38 T 28-03-2018 CDW54_RS03230 5a350b9809126dca127fb2c622496585 554 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 84 472 5.3E-81 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CDW54_RS03230 5a350b9809126dca127fb2c622496585 554 Gene3D G3DSA:3.10.105.10 309 524 3.8E-60 T 28-03-2018 CDW54_RS03230 5a350b9809126dca127fb2c622496585 554 SUPERFAMILY SSF53850 36 551 3.08E-122 T 28-03-2018 CDW54_RS05715 ca64caadcfe434a6a16a89ac1cd72fa7 657 Gene3D G3DSA:3.90.1640.10 315 534 6.8E-43 T 28-03-2018 CDW54_RS05715 ca64caadcfe434a6a16a89ac1cd72fa7 657 Pfam PF02272 DHHA1 domain 518 645 7.7E-10 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CDW54_RS05715 ca64caadcfe434a6a16a89ac1cd72fa7 657 Pfam PF01368 DHH family 338 495 5.2E-19 T 28-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CDW54_RS05715 ca64caadcfe434a6a16a89ac1cd72fa7 657 Gene3D G3DSA:3.30.70.270 146 296 1.2E-5 T 28-03-2018 CDW54_RS05715 ca64caadcfe434a6a16a89ac1cd72fa7 657 SUPERFAMILY SSF64182 338 642 1.57E-64 T 28-03-2018 CDW54_RS05715 ca64caadcfe434a6a16a89ac1cd72fa7 657 SMART SM00267 131 295 4.1E-4 T 28-03-2018 IPR000160 GGDEF domain CDW54_RS05715 ca64caadcfe434a6a16a89ac1cd72fa7 657 PIRSF PIRSF026583 1 656 4.8E-229 T 28-03-2018 IPR014528 Cyclic-di-AMP phosphodiesterase GdpP/PdeA CDW54_RS07400 1f4140d8aa254dc0dee0d5e65dade994 642 SMART SM00533 9 311 3.9E-6 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CDW54_RS07400 1f4140d8aa254dc0dee0d5e65dade994 642 SUPERFAMILY SSF48334 38 286 2.22E-20 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CDW54_RS07400 1f4140d8aa254dc0dee0d5e65dade994 642 SMART SM00534 323 508 1.4E-57 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CDW54_RS07400 1f4140d8aa254dc0dee0d5e65dade994 642 PIRSF PIRSF005814 1 640 6.1E-197 T 28-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 CDW54_RS07400 1f4140d8aa254dc0dee0d5e65dade994 642 Gene3D G3DSA:1.10.1420.10 34 286 3.2E-5 T 28-03-2018 CDW54_RS07400 1f4140d8aa254dc0dee0d5e65dade994 642 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 405 421 - T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CDW54_RS07400 1f4140d8aa254dc0dee0d5e65dade994 642 Pfam PF00488 MutS domain V 326 508 3.8E-36 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CDW54_RS07400 1f4140d8aa254dc0dee0d5e65dade994 642 Gene3D G3DSA:3.40.50.300 288 547 6.5E-31 T 28-03-2018 CDW54_RS07400 1f4140d8aa254dc0dee0d5e65dade994 642 SUPERFAMILY SSF52540 289 508 1.19E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS01165 42bf3159006960a9cde969160dd73337 201 SUPERFAMILY SSF53474 3 194 1.47E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CDW54_RS01165 42bf3159006960a9cde969160dd73337 201 Pfam PF02230 Phospholipase/Carboxylesterase 12 196 4.2E-9 T 28-03-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 CDW54_RS01165 42bf3159006960a9cde969160dd73337 201 Gene3D G3DSA:3.40.50.1820 2 197 2.0E-17 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CDW54_RS09610 5531d9fdb0d3747734f30945e9a58f69 78 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 8.1E-9 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CDW54_RS09610 5531d9fdb0d3747734f30945e9a58f69 78 PRINTS PR01651 Protein-export SecG membrane protein signature 56 78 8.1E-9 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CDW54_RS09610 5531d9fdb0d3747734f30945e9a58f69 78 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 8.1E-9 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CDW54_RS09610 5531d9fdb0d3747734f30945e9a58f69 78 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 2 76 2.0E-21 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CDW54_RS09610 5531d9fdb0d3747734f30945e9a58f69 78 Pfam PF03840 Preprotein translocase SecG subunit 5 75 3.9E-18 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CDW54_RS01460 41d8c39ca1cb4c5354cc49f6ce1c21ea 59 SUPERFAMILY SSF55331 2 57 1.96E-17 T 28-03-2018 IPR014347 Tautomerase/MIF superfamily CDW54_RS01460 41d8c39ca1cb4c5354cc49f6ce1c21ea 59 Gene3D G3DSA:3.30.429.10 2 55 8.0E-16 T 28-03-2018 CDW54_RS01460 41d8c39ca1cb4c5354cc49f6ce1c21ea 59 Pfam PF01361 Tautomerase enzyme 2 56 4.4E-18 T 28-03-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 CDW54_RS01460 41d8c39ca1cb4c5354cc49f6ce1c21ea 59 TIGRFAM TIGR00013 taut: 4-oxalocrotonate tautomerase family enzyme 1 56 4.7E-17 T 28-03-2018 IPR018191 4-oxalocrotonate tautomerase, Pseudomonas-type GO:0006725|GO:0016853 CDW54_RS04500 fa8ffb2ba3e824300e287ba03febab05 104 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 101 8.0E-16 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CDW54_RS04500 fa8ffb2ba3e824300e287ba03febab05 104 Gene3D G3DSA:3.40.50.2300 3 103 4.8E-19 T 28-03-2018 CDW54_RS04500 fa8ffb2ba3e824300e287ba03febab05 104 SUPERFAMILY SSF52794 1 89 3.14E-21 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CDW54_RS07560 45fea2c1fb268086c8238630843f1770 721 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 438 531 9.8E-21 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CDW54_RS07560 45fea2c1fb268086c8238630843f1770 721 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 575 697 8.9E-49 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CDW54_RS07560 45fea2c1fb268086c8238630843f1770 721 TIGRFAM TIGR02003 PTS-II-BC-unk1: PTS system, IIBC component 3 547 1.2E-287 T 28-03-2018 IPR011300 Phosphotransferase system, IIBC component KEGG: 00010+2.7.1.199|KEGG: 00520+2.7.1.199|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 CDW54_RS07560 45fea2c1fb268086c8238630843f1770 721 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 576 696 9.7E-42 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CDW54_RS07560 45fea2c1fb268086c8238630843f1770 721 Gene3D G3DSA:2.70.70.10 563 721 6.9E-54 T 28-03-2018 CDW54_RS07560 45fea2c1fb268086c8238630843f1770 721 SUPERFAMILY SSF55604 472 545 1.24E-19 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CDW54_RS07560 45fea2c1fb268086c8238630843f1770 721 SUPERFAMILY SSF51261 574 716 5.93E-50 T 28-03-2018 IPR011055 Duplicated hybrid motif CDW54_RS07560 45fea2c1fb268086c8238630843f1770 721 Gene3D G3DSA:3.30.1360.60 469 545 4.3E-24 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CDW54_RS07560 45fea2c1fb268086c8238630843f1770 721 Pfam PF02378 Phosphotransferase system, EIIC 14 378 3.6E-53 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CDW54_RS07560 45fea2c1fb268086c8238630843f1770 721 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 484 501 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CDW54_RS07560 45fea2c1fb268086c8238630843f1770 721 Pfam PF00367 phosphotransferase system, EIIB 474 505 4.9E-15 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CDW54_RS07560 45fea2c1fb268086c8238630843f1770 721 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 638 650 - T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CDW54_RS06345 7cb764c5c765cee3150a03ffc944b99f 257 SUPERFAMILY SSF56784 1 254 9.61E-65 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS06345 7cb764c5c765cee3150a03ffc944b99f 257 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 224 5.4E-26 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CDW54_RS06345 7cb764c5c765cee3150a03ffc944b99f 257 Gene3D G3DSA:3.40.50.1000 1 256 1.7E-44 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS06345 7cb764c5c765cee3150a03ffc944b99f 257 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 251 7.7E-56 T 28-03-2018 IPR000150 Cof family GO:0016787 CDW54_RS06345 7cb764c5c765cee3150a03ffc944b99f 257 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 251 1.4E-58 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS00340 1423bc0536ae2639e1c80f2051e72932 325 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 5 309 3.8E-69 T 28-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 CDW54_RS00340 1423bc0536ae2639e1c80f2051e72932 325 SMART SM01240 2 325 8.7E-112 T 28-03-2018 CDW54_RS00340 1423bc0536ae2639e1c80f2051e72932 325 PIRSF PIRSF036500 1 325 6.2E-198 T 28-03-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 CDW54_RS00340 1423bc0536ae2639e1c80f2051e72932 325 TIGRFAM TIGR01306 GMP_reduct_2: guanosine monophosphate reductase 3 323 5.2E-200 T 28-03-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 CDW54_RS00340 1423bc0536ae2639e1c80f2051e72932 325 Hamap MF_01511 GMP reductase [guaC]. 1 324 64.435 T 28-03-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 CDW54_RS00340 1423bc0536ae2639e1c80f2051e72932 325 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 164 176 - T 28-03-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 CDW54_RS00340 1423bc0536ae2639e1c80f2051e72932 325 SUPERFAMILY SSF51412 3 314 1.26E-93 T 28-03-2018 CDW54_RS00340 1423bc0536ae2639e1c80f2051e72932 325 Gene3D G3DSA:3.20.20.70 2 325 2.8E-71 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDW54_RS12075 a628651cf4f4b6fbf7bbc17296d52c27 305 Gene3D G3DSA:1.20.1170.10 13 269 1.4E-5 T 28-03-2018 CDW54_RS02790 44cbcd8bdfd657f07ebc6484cd174f90 100 Gene3D G3DSA:3.40.50.2300 2 100 7.2E-37 T 28-03-2018 CDW54_RS02790 44cbcd8bdfd657f07ebc6484cd174f90 100 SUPERFAMILY SSF52794 1 99 5.49E-35 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CDW54_RS02790 44cbcd8bdfd657f07ebc6484cd174f90 100 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 93 8.2E-23 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CDW54_RS08000 5d949f4b2386a3ed3ebbd0279ed31fc0 456 Pfam PF00324 Amino acid permease 14 453 7.3E-96 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CDW54_RS08000 5d949f4b2386a3ed3ebbd0279ed31fc0 456 PIRSF PIRSF006060 1 456 6.3E-65 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CDW54_RS11995 ae3589e95dbbaf3d7f3dca3f25a851df 433 Gene3D G3DSA:1.10.3720.10 184 426 1.2E-41 T 28-03-2018 CDW54_RS11995 ae3589e95dbbaf3d7f3dca3f25a851df 433 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 210 424 2.5E-27 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS11995 ae3589e95dbbaf3d7f3dca3f25a851df 433 Gene3D G3DSA:1.20.58.370 39 160 2.2E-10 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CDW54_RS11995 ae3589e95dbbaf3d7f3dca3f25a851df 433 SUPERFAMILY SSF160964 123 179 7.72E-10 T 28-03-2018 CDW54_RS11995 ae3589e95dbbaf3d7f3dca3f25a851df 433 SUPERFAMILY SSF160964 61 88 7.72E-10 T 28-03-2018 CDW54_RS11995 ae3589e95dbbaf3d7f3dca3f25a851df 433 SUPERFAMILY SSF161098 176 421 1.44E-47 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS03650 6a2ebb454d9ea4044e390b13ec1481f4 430 PIRSF PIRSF006351 1 427 4.1E-112 T 28-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 CDW54_RS03650 6a2ebb454d9ea4044e390b13ec1481f4 430 Pfam PF02378 Phosphotransferase system, EIIC 26 344 1.2E-48 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CDW54_RS03650 6a2ebb454d9ea4044e390b13ec1481f4 430 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 10 417 3.1E-88 T 28-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 CDW54_RS05900 97a09a70fa9afef0d896df109d4dafec 156 Gene3D G3DSA:1.10.455.10 6 156 3.1E-60 T 28-03-2018 IPR023798 Ribosomal protein S7 domain CDW54_RS05900 97a09a70fa9afef0d896df109d4dafec 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 5.9E-66 T 28-03-2018 IPR023798 Ribosomal protein S7 domain CDW54_RS05900 97a09a70fa9afef0d896df109d4dafec 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 35.414 T 28-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 CDW54_RS05900 97a09a70fa9afef0d896df109d4dafec 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 28-03-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS05900 97a09a70fa9afef0d896df109d4dafec 156 PIRSF PIRSF002122 5 156 5.4E-58 T 28-03-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 CDW54_RS05900 97a09a70fa9afef0d896df109d4dafec 156 SUPERFAMILY SSF47973 1 149 4.06E-61 T 28-03-2018 IPR023798 Ribosomal protein S7 domain CDW54_RS05900 97a09a70fa9afef0d896df109d4dafec 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 1.4E-68 T 28-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 CDW54_RS10415 9e07b9d0cccc889d11f2ddc759bcfe84 253 PIRSF PIRSF000386 1 252 9.4E-103 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CDW54_RS10415 9e07b9d0cccc889d11f2ddc759bcfe84 253 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 228 3.6E-95 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CDW54_RS10415 9e07b9d0cccc889d11f2ddc759bcfe84 253 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 221 6.0E-69 T 28-03-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CDW54_RS10415 9e07b9d0cccc889d11f2ddc759bcfe84 253 SUPERFAMILY SSF75217 1 246 4.86E-99 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CDW54_RS10415 9e07b9d0cccc889d11f2ddc759bcfe84 253 Gene3D G3DSA:3.40.1280.10 1 169 3.6E-76 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CDW54_RS10415 9e07b9d0cccc889d11f2ddc759bcfe84 253 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 253 110.093 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CDW54_RS10415 9e07b9d0cccc889d11f2ddc759bcfe84 253 Gene3D G3DSA:1.10.1270.20 170 253 7.4E-34 T 28-03-2018 CDW54_RS07430 69732f14f08b7f96cc16b9f3a937c6bd 551 Gene3D G3DSA:3.50.50.60 1 136 1.7E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS07430 69732f14f08b7f96cc16b9f3a937c6bd 551 Gene3D G3DSA:3.30.390.30 324 450 2.3E-26 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CDW54_RS07430 69732f14f08b7f96cc16b9f3a937c6bd 551 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 332 427 8.5E-14 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CDW54_RS07430 69732f14f08b7f96cc16b9f3a937c6bd 551 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 304 1.8E-62 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS07430 69732f14f08b7f96cc16b9f3a937c6bd 551 SMART SM00450 448 544 3.3E-15 T 28-03-2018 IPR001763 Rhodanese-like domain CDW54_RS07430 69732f14f08b7f96cc16b9f3a937c6bd 551 Gene3D G3DSA:3.50.50.60 143 323 2.7E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS07430 69732f14f08b7f96cc16b9f3a937c6bd 551 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 9.4E-16 T 28-03-2018 CDW54_RS07430 69732f14f08b7f96cc16b9f3a937c6bd 551 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 233 247 9.4E-16 T 28-03-2018 CDW54_RS07430 69732f14f08b7f96cc16b9f3a937c6bd 551 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 274 281 9.4E-16 T 28-03-2018 CDW54_RS07430 69732f14f08b7f96cc16b9f3a937c6bd 551 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 150 175 9.4E-16 T 28-03-2018 CDW54_RS07430 69732f14f08b7f96cc16b9f3a937c6bd 551 SUPERFAMILY SSF55424 322 443 1.63E-31 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CDW54_RS07430 69732f14f08b7f96cc16b9f3a937c6bd 551 Gene3D G3DSA:3.40.250.10 451 548 2.3E-19 T 28-03-2018 IPR001763 Rhodanese-like domain CDW54_RS07430 69732f14f08b7f96cc16b9f3a937c6bd 551 SUPERFAMILY SSF52821 431 538 1.37E-21 T 28-03-2018 IPR001763 Rhodanese-like domain CDW54_RS07430 69732f14f08b7f96cc16b9f3a937c6bd 551 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 103 121 7.9E-25 T 28-03-2018 CDW54_RS07430 69732f14f08b7f96cc16b9f3a937c6bd 551 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 150 168 7.9E-25 T 28-03-2018 CDW54_RS07430 69732f14f08b7f96cc16b9f3a937c6bd 551 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 7.9E-25 T 28-03-2018 CDW54_RS07430 69732f14f08b7f96cc16b9f3a937c6bd 551 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 281 7.9E-25 T 28-03-2018 CDW54_RS07430 69732f14f08b7f96cc16b9f3a937c6bd 551 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 232 248 7.9E-25 T 28-03-2018 CDW54_RS07430 69732f14f08b7f96cc16b9f3a937c6bd 551 Pfam PF00581 Rhodanese-like domain 458 539 9.1E-8 T 28-03-2018 IPR001763 Rhodanese-like domain CDW54_RS07430 69732f14f08b7f96cc16b9f3a937c6bd 551 SUPERFAMILY SSF51905 1 313 6.48E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS08365 a707c58a3b523cba9c2e0291d1b2093b 205 Gene3D G3DSA:1.10.260.40 4 193 4.9E-13 T 28-03-2018 CDW54_RS08365 a707c58a3b523cba9c2e0291d1b2093b 205 SMART SM00530 7 62 4.4E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDW54_RS08365 a707c58a3b523cba9c2e0291d1b2093b 205 SUPERFAMILY SSF47413 2 58 2.82E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDW54_RS08365 a707c58a3b523cba9c2e0291d1b2093b 205 Pfam PF01381 Helix-turn-helix 9 56 1.2E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDW54_RS06290 b824922c9c692ca29c59d40e0b84eba9 244 TIGRFAM TIGR00861 MIP: MIP family channel proteins 11 238 1.8E-52 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CDW54_RS06290 b824922c9c692ca29c59d40e0b84eba9 244 Gene3D G3DSA:1.20.1080.10 1 244 1.8E-78 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CDW54_RS06290 b824922c9c692ca29c59d40e0b84eba9 244 Pfam PF00230 Major intrinsic protein 6 238 1.3E-42 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CDW54_RS06290 b824922c9c692ca29c59d40e0b84eba9 244 SUPERFAMILY SSF81338 5 243 6.67E-68 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CDW54_RS06290 b824922c9c692ca29c59d40e0b84eba9 244 PRINTS PR00783 Major intrinsic protein family signature 174 196 2.1E-39 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CDW54_RS06290 b824922c9c692ca29c59d40e0b84eba9 244 PRINTS PR00783 Major intrinsic protein family signature 7 26 2.1E-39 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CDW54_RS06290 b824922c9c692ca29c59d40e0b84eba9 244 PRINTS PR00783 Major intrinsic protein family signature 49 73 2.1E-39 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CDW54_RS06290 b824922c9c692ca29c59d40e0b84eba9 244 PRINTS PR00783 Major intrinsic protein family signature 141 159 2.1E-39 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CDW54_RS06290 b824922c9c692ca29c59d40e0b84eba9 244 PRINTS PR00783 Major intrinsic protein family signature 221 241 2.1E-39 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CDW54_RS06290 b824922c9c692ca29c59d40e0b84eba9 244 PRINTS PR00783 Major intrinsic protein family signature 86 105 2.1E-39 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CDW54_RS06290 b824922c9c692ca29c59d40e0b84eba9 244 ProSitePatterns PS00221 MIP family signature. 67 75 - T 28-03-2018 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CDW54_RS11205 8f6839f9726333ba2ba34a37cc4156bf 351 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 1 296 1.9E-82 T 28-03-2018 IPR005218 Diacylglycerol/lipid kinase CDW54_RS11205 8f6839f9726333ba2ba34a37cc4156bf 351 SUPERFAMILY SSF111331 1 302 1.09E-76 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CDW54_RS11205 8f6839f9726333ba2ba34a37cc4156bf 351 Gene3D G3DSA:3.40.50.10330 1 133 1.5E-31 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CDW54_RS11205 8f6839f9726333ba2ba34a37cc4156bf 351 SMART SM00046 3 127 1.3E-11 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CDW54_RS11205 8f6839f9726333ba2ba34a37cc4156bf 351 Pfam PF00781 Diacylglycerol kinase catalytic domain 4 127 9.7E-35 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CDW54_RS07135 26347744ecd1568bf677d36c93ab830f 564 SUPERFAMILY SSF51905 132 276 3.82E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS07135 26347744ecd1568bf677d36c93ab830f 564 SUPERFAMILY SSF51905 64 104 3.82E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS07135 26347744ecd1568bf677d36c93ab830f 564 SUPERFAMILY SSF51905 1 35 3.82E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS07135 26347744ecd1568bf677d36c93ab830f 564 Gene3D G3DSA:3.50.50.60 5 503 2.0E-6 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS07135 26347744ecd1568bf677d36c93ab830f 564 Pfam PF06100 MCRA family 4 531 1.4E-175 T 28-03-2018 IPR010354 Oleate hydratase GO:0006631|GO:0050151|GO:0071949 CDW54_RS06540 b767b4054472ae058c3a68798014bd72 200 Pfam PF09335 SNARE associated Golgi protein 70 176 6.2E-19 T 28-03-2018 IPR032816 SNARE associated Golgi protein CDW54_RS02500 ea09dcf35e2158bf73b06fd72293dfa3 245 SUPERFAMILY SSF51695 3 238 6.8E-65 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CDW54_RS02500 ea09dcf35e2158bf73b06fd72293dfa3 245 Gene3D G3DSA:3.20.20.190 1 245 1.9E-64 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CDW54_RS02500 ea09dcf35e2158bf73b06fd72293dfa3 245 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 7 234 1.1E-41 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CDW54_RS05325 39e2bb6d50a191999a6069c402ea93a5 427 Pfam PF13416 Bacterial extracellular solute-binding protein 51 358 5.4E-32 T 28-03-2018 CDW54_RS05325 39e2bb6d50a191999a6069c402ea93a5 427 SUPERFAMILY SSF53850 30 425 2.28E-65 T 28-03-2018 CDW54_RS05325 39e2bb6d50a191999a6069c402ea93a5 427 Gene3D G3DSA:3.40.190.10 148 427 7.2E-40 T 28-03-2018 CDW54_RS01870 cdf84c4c69404504e8751cb5fa99b064 342 SUPERFAMILY SSF51735 1 329 3.33E-95 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS01870 cdf84c4c69404504e8751cb5fa99b064 342 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 4 328 3.7E-136 T 28-03-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 CDW54_RS01870 cdf84c4c69404504e8751cb5fa99b064 342 Gene3D G3DSA:3.90.25.10 193 342 4.9E-40 T 28-03-2018 CDW54_RS01870 cdf84c4c69404504e8751cb5fa99b064 342 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 314 5.7E-76 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS01870 cdf84c4c69404504e8751cb5fa99b064 342 Gene3D G3DSA:3.40.50.720 2 192 1.2E-38 T 28-03-2018 CDW54_RS11665 65c7bf71b8a17f4e248fe7ae4ddca954 295 Gene3D G3DSA:1.10.4030.10 25 130 5.9E-4 T 28-03-2018 CDW54_RS11665 65c7bf71b8a17f4e248fe7ae4ddca954 295 SUPERFAMILY SSF109998 29 173 6.28E-13 T 28-03-2018 IPR027304 Trigger factor/SurA domain CDW54_RS11665 65c7bf71b8a17f4e248fe7ae4ddca954 295 SUPERFAMILY SSF54534 128 225 2.42E-14 T 28-03-2018 CDW54_RS11665 65c7bf71b8a17f4e248fe7ae4ddca954 295 Pfam PF13145 PPIC-type PPIASE domain 144 243 4.9E-10 T 28-03-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 CDW54_RS11665 65c7bf71b8a17f4e248fe7ae4ddca954 295 Hamap MF_01145 Foldase protein PrsA [prsA]. 7 295 16.152 T 28-03-2018 IPR023059 Foldase protein PrsA GO:0003755 CDW54_RS11665 65c7bf71b8a17f4e248fe7ae4ddca954 295 Gene3D G3DSA:3.10.50.40 137 266 1.6E-15 T 28-03-2018 CDW54_RS10655 06caaa4831e75098c7ff831e724360ff 324 SUPERFAMILY SSF56235 2 324 3.16E-106 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CDW54_RS10655 06caaa4831e75098c7ff831e724360ff 324 Gene3D G3DSA:3.60.60.10 2 324 7.5E-87 T 28-03-2018 CDW54_RS10655 06caaa4831e75098c7ff831e724360ff 324 Pfam PF02275 Linear amide C-N hydrolases, choloylglycine hydrolase family 2 312 4.4E-107 T 28-03-2018 IPR029132 Choloylglycine hydrolase/NAAA C-terminal CDW54_RS07790 c568a1758e52daa1e60beda1886bcc41 242 Gene3D G3DSA:2.40.50.40 142 210 1.2E-14 T 28-03-2018 CDW54_RS07790 c568a1758e52daa1e60beda1886bcc41 242 Gene3D G3DSA:3.40.50.2300 1 141 1.9E-12 T 28-03-2018 CDW54_RS07790 c568a1758e52daa1e60beda1886bcc41 242 SMART SM00448 2 123 1.8E-6 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDW54_RS07790 c568a1758e52daa1e60beda1886bcc41 242 Pfam PF00072 Response regulator receiver domain 4 123 1.1E-12 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDW54_RS07790 c568a1758e52daa1e60beda1886bcc41 242 SUPERFAMILY SSF52172 2 131 1.57E-11 T 28-03-2018 IPR011006 CheY-like superfamily CDW54_RS07790 c568a1758e52daa1e60beda1886bcc41 242 SMART SM00850 150 242 4.5E-19 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CDW54_RS07790 c568a1758e52daa1e60beda1886bcc41 242 Pfam PF04397 LytTr DNA-binding domain 151 240 9.1E-21 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CDW54_RS05535 bdb2bb551cd6d0197b9de2670b7f1e41 402 SMART SM00387 276 387 9.7E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS05535 bdb2bb551cd6d0197b9de2670b7f1e41 402 Pfam PF00512 His Kinase A (phospho-acceptor) domain 163 227 1.4E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDW54_RS05535 bdb2bb551cd6d0197b9de2670b7f1e41 402 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 276 385 4.4E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS05535 bdb2bb551cd6d0197b9de2670b7f1e41 402 SMART SM00388 163 230 2.1E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDW54_RS05535 bdb2bb551cd6d0197b9de2670b7f1e41 402 Gene3D G3DSA:1.10.287.130 153 226 3.0E-15 T 28-03-2018 CDW54_RS05535 bdb2bb551cd6d0197b9de2670b7f1e41 402 SUPERFAMILY SSF47384 147 228 9.81E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDW54_RS05535 bdb2bb551cd6d0197b9de2670b7f1e41 402 PRINTS PR00344 Bacterial sensor protein C-terminal signature 331 341 1.2E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDW54_RS05535 bdb2bb551cd6d0197b9de2670b7f1e41 402 PRINTS PR00344 Bacterial sensor protein C-terminal signature 313 327 1.2E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDW54_RS05535 bdb2bb551cd6d0197b9de2670b7f1e41 402 PRINTS PR00344 Bacterial sensor protein C-terminal signature 371 384 1.2E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDW54_RS05535 bdb2bb551cd6d0197b9de2670b7f1e41 402 PRINTS PR00344 Bacterial sensor protein C-terminal signature 348 366 1.2E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDW54_RS05535 bdb2bb551cd6d0197b9de2670b7f1e41 402 Gene3D G3DSA:3.30.565.10 236 389 1.0E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS05535 bdb2bb551cd6d0197b9de2670b7f1e41 402 SUPERFAMILY SSF55874 219 389 1.7E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS08860 93bf0ed2f0b183d8703cde8f84a43db7 223 SUPERFAMILY SSF56784 1 188 2.62E-42 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS08860 93bf0ed2f0b183d8703cde8f84a43db7 223 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 183 1.3E-29 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS08860 93bf0ed2f0b183d8703cde8f84a43db7 223 Gene3D G3DSA:3.40.50.1000 73 220 1.7E-24 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS08860 93bf0ed2f0b183d8703cde8f84a43db7 223 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 68 184 1.9E-10 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDW54_RS08860 93bf0ed2f0b183d8703cde8f84a43db7 223 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 173 186 1.5E-6 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDW54_RS08860 93bf0ed2f0b183d8703cde8f84a43db7 223 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 1 12 1.5E-6 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDW54_RS08860 93bf0ed2f0b183d8703cde8f84a43db7 223 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 97 110 1.5E-6 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDW54_RS08860 93bf0ed2f0b183d8703cde8f84a43db7 223 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 128 144 1.5E-6 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDW54_RS08860 93bf0ed2f0b183d8703cde8f84a43db7 223 Gene3D G3DSA:1.10.150.240 14 72 5.7E-5 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CDW54_RS01545 cc9f733d21b2c0f416569149edb56d3d 158 Gene3D G3DSA:2.40.50.100 5 157 9.5E-20 T 28-03-2018 CDW54_RS01545 cc9f733d21b2c0f416569149edb56d3d 158 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 1 156 1.3E-42 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CDW54_RS01545 cc9f733d21b2c0f416569149edb56d3d 158 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 102 116 5.5E-14 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CDW54_RS01545 cc9f733d21b2c0f416569149edb56d3d 158 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 85 98 5.5E-14 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CDW54_RS01545 cc9f733d21b2c0f416569149edb56d3d 158 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 117 130 5.5E-14 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CDW54_RS01545 cc9f733d21b2c0f416569149edb56d3d 158 Pfam PF00364 Biotin-requiring enzyme 82 155 1.2E-20 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CDW54_RS01545 cc9f733d21b2c0f416569149edb56d3d 158 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 112 129 - T 28-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CDW54_RS01545 cc9f733d21b2c0f416569149edb56d3d 158 SUPERFAMILY SSF51230 80 155 2.49E-23 T 28-03-2018 IPR011053 Single hybrid motif CDW54_RS11190 cf5659317c98da8a36bcc2aeb8437d3c 101 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 2 95 24.631 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CDW54_RS11190 cf5659317c98da8a36bcc2aeb8437d3c 101 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 3 95 7.1E-32 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CDW54_RS11190 cf5659317c98da8a36bcc2aeb8437d3c 101 SUPERFAMILY SSF141000 3 93 2.62E-30 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CDW54_RS11190 cf5659317c98da8a36bcc2aeb8437d3c 101 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 20 90 3.8E-20 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CDW54_RS09670 5e6e3cb2c70ae19d1b86d6ec204603ca 76 SUPERFAMILY SSF48050 18 72 4.84E-5 T 28-03-2018 IPR005204 Hemocyanin, N-terminal CDW54_RS09670 5e6e3cb2c70ae19d1b86d6ec204603ca 76 TIGRFAM TIGR02327 int_mem_ywzB: conserved hypothetical integral membrane protein 10 75 9.9E-24 T 28-03-2018 IPR009526 Protein of unknown function DUF1146 CDW54_RS09670 5e6e3cb2c70ae19d1b86d6ec204603ca 76 Pfam PF06612 Protein of unknown function (DUF1146) 16 63 7.1E-19 T 28-03-2018 IPR009526 Protein of unknown function DUF1146 CDW54_RS01920 19b7dadb9129369b9f2e2e4a88b7a75e 189 SUPERFAMILY SSF48498 78 180 8.0E-9 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CDW54_RS01920 19b7dadb9129369b9f2e2e4a88b7a75e 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 58 5.8E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDW54_RS01920 19b7dadb9129369b9f2e2e4a88b7a75e 189 SUPERFAMILY SSF46689 2 69 8.98E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDW54_RS01920 19b7dadb9129369b9f2e2e4a88b7a75e 189 Pfam PF13305 WHG domain 83 158 1.9E-7 T 28-03-2018 IPR025996 WHG domain CDW54_RS01920 19b7dadb9129369b9f2e2e4a88b7a75e 189 Gene3D G3DSA:1.10.10.60 2 59 3.4E-13 T 28-03-2018 CDW54_RS01920 19b7dadb9129369b9f2e2e4a88b7a75e 189 Gene3D G3DSA:1.10.357.10 60 182 4.0E-4 T 28-03-2018 CDW54_RS11880 abfef9b5fd4aa2bea08a593c28bb99cd 227 Hamap MF_01235 Putative N-acetylmannosamine-6-phosphate 2-epimerase [nanE]. 5 223 39.74 T 28-03-2018 IPR007260 Putative N-acetylmannosamine-6-phosphate epimerase GO:0006051|GO:0047465 KEGG: 00520+5.1.3.9 CDW54_RS11880 abfef9b5fd4aa2bea08a593c28bb99cd 227 Pfam PF04131 Putative N-acetylmannosamine-6-phosphate epimerase 29 222 1.4E-70 T 28-03-2018 IPR007260 Putative N-acetylmannosamine-6-phosphate epimerase GO:0006051|GO:0047465 KEGG: 00520+5.1.3.9 CDW54_RS11880 abfef9b5fd4aa2bea08a593c28bb99cd 227 Gene3D G3DSA:3.20.20.70 1 227 2.8E-39 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDW54_RS11880 abfef9b5fd4aa2bea08a593c28bb99cd 227 SUPERFAMILY SSF51366 5 220 3.14E-61 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CDW54_RS03215 e204c87a5a83f93e5f2d54f6ba093aa4 347 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 163 346 1.2E-33 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS03215 e204c87a5a83f93e5f2d54f6ba093aa4 347 SUPERFAMILY SSF161098 140 327 2.62E-27 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS03215 e204c87a5a83f93e5f2d54f6ba093aa4 347 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 40 91 4.4E-15 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CDW54_RS03215 e204c87a5a83f93e5f2d54f6ba093aa4 347 Gene3D G3DSA:1.10.3720.10 42 335 3.3E-43 T 28-03-2018 CDW54_RS06320 05e3cfd718235054f06f2efecbe5712f 169 PIRSF PIRSF031501 1 169 3.8E-55 T 28-03-2018 IPR010387 Queuosine precursor transporter QueT GO:0005886 CDW54_RS06320 05e3cfd718235054f06f2efecbe5712f 169 Pfam PF06177 QueT transporter 17 161 3.2E-32 T 28-03-2018 IPR010387 Queuosine precursor transporter QueT GO:0005886 CDW54_RS10710 602a290f4c3ce346a52679346778015e 70 Pfam PF06014 Bacterial protein of unknown function (DUF910) 1 61 1.9E-29 T 28-03-2018 IPR009256 Protein of unknown function DUF910 CDW54_RS10710 602a290f4c3ce346a52679346778015e 70 SUPERFAMILY SSF158379 1 62 1.1E-24 T 28-03-2018 IPR023164 YqgQ-like domain CDW54_RS10710 602a290f4c3ce346a52679346778015e 70 Gene3D G3DSA:1.10.287.760 1 65 3.5E-30 T 28-03-2018 IPR023164 YqgQ-like domain CDW54_RS02935 168ce66de556f50be85adf01b55372ff 254 Gene3D G3DSA:3.40.50.1000 72 181 1.1E-29 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS02935 168ce66de556f50be85adf01b55372ff 254 SUPERFAMILY SSF56784 2 252 7.31E-71 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS02935 168ce66de556f50be85adf01b55372ff 254 TIGRFAM TIGR01457 HAD-SF-IIA-hyp2: HAD hydrolase, TIGR01457 family 3 252 2.4E-108 T 28-03-2018 IPR006354 HAD-superfamily hydrolase, subfamily IIA, hypothetical 1 CDW54_RS02935 168ce66de556f50be85adf01b55372ff 254 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 7 228 2.2E-39 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CDW54_RS02935 168ce66de556f50be85adf01b55372ff 254 PIRSF PIRSF000915 1 115 2.1E-22 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CDW54_RS02935 168ce66de556f50be85adf01b55372ff 254 PIRSF PIRSF000915 107 247 2.4E-33 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CDW54_RS02935 168ce66de556f50be85adf01b55372ff 254 Pfam PF13242 HAD-hyrolase-like 179 251 6.1E-19 T 28-03-2018 CDW54_RS02935 168ce66de556f50be85adf01b55372ff 254 Pfam PF13344 Haloacid dehalogenase-like hydrolase 7 107 9.3E-23 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CDW54_RS09135 7d57b94946e853004917c31c9d241c5d 327 Gene3D G3DSA:3.90.180.10 1 131 5.3E-34 T 28-03-2018 CDW54_RS09135 7d57b94946e853004917c31c9d241c5d 327 Pfam PF00107 Zinc-binding dehydrogenase 149 276 2.3E-30 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CDW54_RS09135 7d57b94946e853004917c31c9d241c5d 327 Gene3D G3DSA:3.40.50.720 132 309 6.6E-44 T 28-03-2018 CDW54_RS09135 7d57b94946e853004917c31c9d241c5d 327 SUPERFAMILY SSF51735 110 283 2.37E-50 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS09135 7d57b94946e853004917c31c9d241c5d 327 SMART SM00829 10 323 6.8E-38 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CDW54_RS09135 7d57b94946e853004917c31c9d241c5d 327 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 84 1.7E-5 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CDW54_RS09135 7d57b94946e853004917c31c9d241c5d 327 SUPERFAMILY SSF50129 1 138 1.26E-32 T 28-03-2018 IPR011032 GroES-like CDW54_RS09135 7d57b94946e853004917c31c9d241c5d 327 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 1 325 1.6E-112 T 28-03-2018 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 CDW54_RS00450 1ea8a8bacb454f587a8571962d1f6d5a 435 TIGRFAM TIGR03173 pbuX: xanthine permease 13 420 3.3E-163 T 28-03-2018 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 CDW54_RS00450 1ea8a8bacb454f587a8571962d1f6d5a 435 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 9 418 1.8E-132 T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CDW54_RS00450 1ea8a8bacb454f587a8571962d1f6d5a 435 Pfam PF00860 Permease family 9 385 1.9E-108 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CDW54_RS00450 1ea8a8bacb454f587a8571962d1f6d5a 435 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 335 355 - T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CDW54_RS01465 de33dc2e08a8be839c76cec07d697936 607 Pfam PF00122 E1-E2 ATPase 112 282 8.5E-43 T 28-03-2018 CDW54_RS01465 de33dc2e08a8be839c76cec07d697936 607 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 304 310 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CDW54_RS01465 de33dc2e08a8be839c76cec07d697936 607 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 302 316 1.8E-24 T 28-03-2018 CDW54_RS01465 de33dc2e08a8be839c76cec07d697936 607 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 160 174 1.8E-24 T 28-03-2018 CDW54_RS01465 de33dc2e08a8be839c76cec07d697936 607 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 411 422 1.8E-24 T 28-03-2018 CDW54_RS01465 de33dc2e08a8be839c76cec07d697936 607 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 434 444 1.8E-24 T 28-03-2018 CDW54_RS01465 de33dc2e08a8be839c76cec07d697936 607 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 487 506 1.8E-24 T 28-03-2018 CDW54_RS01465 de33dc2e08a8be839c76cec07d697936 607 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 511 523 1.8E-24 T 28-03-2018 CDW54_RS01465 de33dc2e08a8be839c76cec07d697936 607 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 519 544 7.2E-6 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDW54_RS01465 de33dc2e08a8be839c76cec07d697936 607 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 487 503 7.2E-6 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDW54_RS01465 de33dc2e08a8be839c76cec07d697936 607 Gene3D G3DSA:3.40.1110.10 314 413 8.2E-20 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CDW54_RS01465 de33dc2e08a8be839c76cec07d697936 607 Gene3D G3DSA:3.40.50.1000 414 552 3.8E-36 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS01465 de33dc2e08a8be839c76cec07d697936 607 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 60 590 3.4E-155 T 28-03-2018 CDW54_RS01465 de33dc2e08a8be839c76cec07d697936 607 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 60 589 4.7E-162 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CDW54_RS01465 de33dc2e08a8be839c76cec07d697936 607 Gene3D G3DSA:2.70.150.10 20 211 4.6E-30 T 28-03-2018 CDW54_RS01465 de33dc2e08a8be839c76cec07d697936 607 Pfam PF00702 haloacid dehalogenase-like hydrolase 299 501 3.3E-29 T 28-03-2018 CDW54_RS01465 de33dc2e08a8be839c76cec07d697936 607 SUPERFAMILY SSF81653 113 210 1.01E-22 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CDW54_RS01465 de33dc2e08a8be839c76cec07d697936 607 SUPERFAMILY SSF81665 211 296 4.05E-8 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CDW54_RS01465 de33dc2e08a8be839c76cec07d697936 607 SUPERFAMILY SSF81665 346 361 4.05E-8 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CDW54_RS01465 de33dc2e08a8be839c76cec07d697936 607 SUPERFAMILY SSF81665 67 114 4.05E-8 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CDW54_RS01465 de33dc2e08a8be839c76cec07d697936 607 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 82 570 3.8E-77 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDW54_RS01465 de33dc2e08a8be839c76cec07d697936 607 SUPERFAMILY SSF56784 357 587 7.42E-49 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS01465 de33dc2e08a8be839c76cec07d697936 607 SUPERFAMILY SSF56784 300 320 7.42E-49 T 28-03-2018 IPR023214 HAD-like domain CDW54_RS10060 c629092aa23f1b95de6cbb36d9ab2719 251 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 59 225 5.9E-56 T 28-03-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 CDW54_RS10060 c629092aa23f1b95de6cbb36d9ab2719 251 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 54 228 2.0E-53 T 28-03-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 CDW54_RS01690 8987699a1da272c15dbe196f07661f7a 184 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 19 181 2.6E-36 T 28-03-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal CDW54_RS01690 8987699a1da272c15dbe196f07661f7a 184 Gene3D G3DSA:2.70.50.50 19 184 6.7E-54 T 28-03-2018 CDW54_RS01690 8987699a1da272c15dbe196f07661f7a 184 SUPERFAMILY SSF81296 19 183 4.2E-53 T 28-03-2018 IPR014756 Immunoglobulin E-set CDW54_RS03830 e81f1544542b5cb96cd74447b9421bc6 167 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 8 144 0.001 T 28-03-2018 CDW54_RS03830 e81f1544542b5cb96cd74447b9421bc6 167 Pfam PF00466 Ribosomal protein L10 7 102 2.3E-29 T 28-03-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 CDW54_RS03830 e81f1544542b5cb96cd74447b9421bc6 167 ProSitePatterns PS01109 Ribosomal protein L10 signature. 9 43 - T 28-03-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS03830 e81f1544542b5cb96cd74447b9421bc6 167 SUPERFAMILY SSF160369 6 161 1.57E-55 T 28-03-2018 CDW54_RS03830 e81f1544542b5cb96cd74447b9421bc6 167 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 4 162 28.679 T 28-03-2018 IPR022973 Ribosomal protein L10 CDW54_RS06405 dba9aa7c7b264469a0ef347e96e2ee82 192 Pfam PF14278 Transcriptional regulator C-terminal region 82 154 1.2E-7 T 28-03-2018 CDW54_RS06405 dba9aa7c7b264469a0ef347e96e2ee82 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 55 3.4E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDW54_RS06405 dba9aa7c7b264469a0ef347e96e2ee82 192 Gene3D G3DSA:1.10.357.10 2 178 2.5E-22 T 28-03-2018 CDW54_RS06405 dba9aa7c7b264469a0ef347e96e2ee82 192 SUPERFAMILY SSF46689 3 61 2.19E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDW54_RS07075 6151a899531b9800cba83c23591bd92a 232 SMART SM00895 95 217 4.0E-21 T 28-03-2018 IPR011711 GntR, C-terminal CDW54_RS07075 6151a899531b9800cba83c23591bd92a 232 SMART SM00345 11 70 3.7E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDW54_RS07075 6151a899531b9800cba83c23591bd92a 232 SUPERFAMILY SSF46785 4 74 2.33E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS07075 6151a899531b9800cba83c23591bd92a 232 Gene3D G3DSA:1.20.120.530 89 232 1.5E-25 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CDW54_RS07075 6151a899531b9800cba83c23591bd92a 232 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 30 44 7.8E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDW54_RS07075 6151a899531b9800cba83c23591bd92a 232 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 60 7.8E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDW54_RS07075 6151a899531b9800cba83c23591bd92a 232 Pfam PF07729 FCD domain 95 216 2.8E-21 T 28-03-2018 IPR011711 GntR, C-terminal CDW54_RS07075 6151a899531b9800cba83c23591bd92a 232 Gene3D G3DSA:1.10.10.10 1 72 5.7E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS07075 6151a899531b9800cba83c23591bd92a 232 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 70 8.6E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDW54_RS07075 6151a899531b9800cba83c23591bd92a 232 SUPERFAMILY SSF48008 93 225 9.15E-24 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CDW54_RS07220 d6724b929fc2cabc3376d2d2110a4931 99 Pfam PF06857 Malonate decarboxylase delta subunit (MdcD) 16 94 5.0E-22 T 28-03-2018 IPR023439 Malonate decarboxylase/citrate lyase acyl carrier protein CDW54_RS07220 d6724b929fc2cabc3376d2d2110a4931 99 TIGRFAM TIGR03130 malonate_delta: malonate decarboxylase acyl carrier protein 2 95 2.6E-36 T 28-03-2018 IPR009662 Malonate decarboxylase delta subunit CDW54_RS07220 d6724b929fc2cabc3376d2d2110a4931 99 ProDom PD015450 MALONATE DECARBOXYLASE SUBUNIT DELTA ACYL CARRIER DECARBOXYLASE PLASMID DIRECT SEQUENCING 1 93 2.0E-50 T 28-03-2018 IPR009662 Malonate decarboxylase delta subunit CDW54_RS07220 d6724b929fc2cabc3376d2d2110a4931 99 Hamap MF_00710 Malonate decarboxylase acyl carrier protein [mdcC]. 1 99 37.822 T 28-03-2018 IPR009662 Malonate decarboxylase delta subunit CDW54_RS02305 4aaca25388788463c7b3c70bab97220b 729 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 138 727 6.3E-186 T 28-03-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2 CDW54_RS02305 4aaca25388788463c7b3c70bab97220b 729 SUPERFAMILY SSF51998 143 709 3.71E-200 T 28-03-2018 CDW54_RS02305 4aaca25388788463c7b3c70bab97220b 729 ProSitePatterns PS00850 Glycine radical domain signature. 698 706 - T 28-03-2018 IPR019777 Formate C-acetyltransferase glycine radical, conserved site CDW54_RS02305 4aaca25388788463c7b3c70bab97220b 729 Gene3D G3DSA:3.20.70.20 143 709 2.4E-209 T 28-03-2018 CDW54_RS02305 4aaca25388788463c7b3c70bab97220b 729 Pfam PF03477 ATP cone domain 20 112 1.6E-19 T 28-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 CDW54_RS02305 4aaca25388788463c7b3c70bab97220b 729 TIGRFAM TIGR02487 NrdD: anaerobic ribonucleoside-triphosphate reductase 137 727 3.1E-188 T 28-03-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2 CDW54_RS08690 2a28a613fae21a88311f73e8e5aa1ada 221 Pfam PF01381 Helix-turn-helix 7 59 1.3E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDW54_RS08690 2a28a613fae21a88311f73e8e5aa1ada 221 SMART SM00530 6 61 1.7E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDW54_RS08690 2a28a613fae21a88311f73e8e5aa1ada 221 SUPERFAMILY SSF47413 1 60 1.29E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDW54_RS08690 2a28a613fae21a88311f73e8e5aa1ada 221 Gene3D G3DSA:1.10.3100.10 1 153 1.6E-17 T 28-03-2018 IPR027910 YdiL-like domain CDW54_RS01885 c1f31a1df445332b8d535822bc3bea0f 244 SUPERFAMILY SSF53448 12 214 1.41E-41 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDW54_RS01885 c1f31a1df445332b8d535822bc3bea0f 244 Gene3D G3DSA:3.90.550.10 12 244 8.2E-34 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDW54_RS01885 c1f31a1df445332b8d535822bc3bea0f 244 Pfam PF00535 Glycosyl transferase family 2 12 138 2.2E-26 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CDW54_RS10370 811d3090fd0bfecaf41836001d046f73 112 SUPERFAMILY SSF88659 2 102 2.99E-33 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDW54_RS10370 811d3090fd0bfecaf41836001d046f73 112 Pfam PF04297 Putative helix-turn-helix protein, YlxM / p13 like 3 93 1.1E-39 T 28-03-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like CDW54_RS10370 811d3090fd0bfecaf41836001d046f73 112 Hamap MF_00245 UPF0122 protein . 3 104 21.447 T 28-03-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like CDW54_RS10370 811d3090fd0bfecaf41836001d046f73 112 Gene3D G3DSA:1.10.10.10 1 111 3.7E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS08180 73a12a063d29b521662cef7128eec769 230 Hamap MF_01684 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase [mtnN]. 2 229 39.161 T 28-03-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CDW54_RS08180 73a12a063d29b521662cef7128eec769 230 SUPERFAMILY SSF53167 1 229 9.16E-72 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CDW54_RS08180 73a12a063d29b521662cef7128eec769 230 Gene3D G3DSA:3.40.50.1580 1 230 7.0E-56 T 28-03-2018 CDW54_RS08180 73a12a063d29b521662cef7128eec769 230 Pfam PF01048 Phosphorylase superfamily 2 226 1.9E-48 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CDW54_RS08180 73a12a063d29b521662cef7128eec769 230 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 2 229 9.3E-71 T 28-03-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CDW54_RS12530 71b1d13c2ccaaff41b8712785c3ea0d6 179 PIRSF PIRSF021290 4 179 1.5E-64 T 28-03-2018 IPR010697 Protein of unknown function DUF1273 CDW54_RS12530 71b1d13c2ccaaff41b8712785c3ea0d6 179 Hamap MF_01575 UPF0398 protein . 4 179 33.905 T 28-03-2018 IPR010697 Protein of unknown function DUF1273 CDW54_RS12530 71b1d13c2ccaaff41b8712785c3ea0d6 179 Gene3D G3DSA:3.40.50.450 3 179 7.2E-31 T 28-03-2018 CDW54_RS12530 71b1d13c2ccaaff41b8712785c3ea0d6 179 SUPERFAMILY SSF102405 5 178 4.39E-61 T 28-03-2018 CDW54_RS12530 71b1d13c2ccaaff41b8712785c3ea0d6 179 Pfam PF06908 Protein of unknown function (DUF1273) 7 174 6.7E-69 T 28-03-2018 IPR010697 Protein of unknown function DUF1273 CDW54_RS00490 e237f3199925bcc5bb91d42193bdbdc8 205 SMART SM00047 46 203 4.5E-52 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CDW54_RS00490 e237f3199925bcc5bb91d42193bdbdc8 205 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 62 199 2.4E-27 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CDW54_RS00490 e237f3199925bcc5bb91d42193bdbdc8 205 Gene3D G3DSA:1.10.530.10 50 203 1.4E-44 T 28-03-2018 CDW54_RS07030 84c8055c06ff8922fe15518a8e77cfe0 672 SUPERFAMILY SSF53649 365 535 2.88E-10 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CDW54_RS07030 84c8055c06ff8922fe15518a8e77cfe0 672 Pfam PF00884 Sulfatase 297 587 3.0E-30 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CDW54_RS07030 84c8055c06ff8922fe15518a8e77cfe0 672 Gene3D G3DSA:3.40.720.10 298 623 6.1E-13 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CDW54_RS05275 b4e07a97cdb4cfca7a793d11481753dd 228 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 6 86 4.7E-22 T 28-03-2018 IPR010627 Peptidase A24A, N-terminal CDW54_RS05680 539b5664dcfb2aabee93bf9a9e391145 80 Gene3D G3DSA:3.10.290.10 7 77 2.6E-9 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDW54_RS05680 539b5664dcfb2aabee93bf9a9e391145 80 TIGRFAM TIGR02988 YaaA_near_RecF: S4 domain protein YaaA 4 63 5.0E-30 T 28-03-2018 IPR014330 RNA-binding S4-related,YaaA CDW54_RS05680 539b5664dcfb2aabee93bf9a9e391145 80 SUPERFAMILY SSF55174 3 68 8.68E-20 T 28-03-2018 CDW54_RS05680 539b5664dcfb2aabee93bf9a9e391145 80 Pfam PF13275 S4 domain 7 62 1.7E-24 T 28-03-2018 CDW54_RS09345 4b271793ebfb1077172512a2aeee38fb 222 SUPERFAMILY SSF52540 4 220 5.33E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS09345 4b271793ebfb1077172512a2aeee38fb 222 SMART SM00382 32 217 5.3E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS09345 4b271793ebfb1077172512a2aeee38fb 222 Pfam PF00005 ABC transporter 23 169 2.7E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS09345 4b271793ebfb1077172512a2aeee38fb 222 Gene3D G3DSA:3.40.50.300 1 222 1.5E-63 T 28-03-2018 CDW54_RS09345 4b271793ebfb1077172512a2aeee38fb 222 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS06455 3e86d4d551baf177b781442dce9867a7 241 Pfam PF02146 Sir2 family 24 191 4.9E-42 T 28-03-2018 IPR003000 Sirtuin family GO:0070403 CDW54_RS06455 3e86d4d551baf177b781442dce9867a7 241 Gene3D G3DSA:3.40.50.1220 1 239 1.3E-48 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CDW54_RS06455 3e86d4d551baf177b781442dce9867a7 241 SUPERFAMILY SSF52467 4 230 8.07E-64 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CDW54_RS04965 40280cb1de279f525cee91d506c60f6f 323 Pfam PF14572 Phosphoribosyl synthetase-associated domain 210 318 6.3E-23 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CDW54_RS04965 40280cb1de279f525cee91d506c60f6f 323 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 10 126 3.0E-52 T 28-03-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CDW54_RS04965 40280cb1de279f525cee91d506c60f6f 323 SUPERFAMILY SSF53271 75 311 5.7E-65 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CDW54_RS04965 40280cb1de279f525cee91d506c60f6f 323 SMART SM01400 10 126 2.7E-83 T 28-03-2018 CDW54_RS04965 40280cb1de279f525cee91d506c60f6f 323 Gene3D G3DSA:3.40.50.2020 8 163 6.6E-70 T 28-03-2018 CDW54_RS04965 40280cb1de279f525cee91d506c60f6f 323 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 11 319 1.3E-124 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CDW54_RS04965 40280cb1de279f525cee91d506c60f6f 323 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 134 149 - T 28-03-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 CDW54_RS04965 40280cb1de279f525cee91d506c60f6f 323 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 10 319 50.965 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CDW54_RS04965 40280cb1de279f525cee91d506c60f6f 323 Gene3D G3DSA:3.40.50.2020 164 295 1.5E-40 T 28-03-2018 CDW54_RS01515 1270ff144ea6219d30fc9d3bf665acb4 369 SUPERFAMILY SSF52540 73 284 2.13E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS01515 1270ff144ea6219d30fc9d3bf665acb4 369 Gene3D G3DSA:3.40.50.300 60 228 2.9E-31 T 28-03-2018 CDW54_RS01515 1270ff144ea6219d30fc9d3bf665acb4 369 Pfam PF01926 50S ribosome-binding GTPase 166 240 2.2E-14 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CDW54_RS01515 1270ff144ea6219d30fc9d3bf665acb4 369 TIGRFAM TIGR03597 GTPase_YqeH: ribosome biogenesis GTPase YqeH 6 369 1.5E-156 T 28-03-2018 IPR019988 GTP-binding protein, riobosome biogenesis, YqeH CDW54_RS02980 0247d54a3a5c2244400c228c94799622 178 Gene3D G3DSA:1.10.10.60 9 177 1.3E-6 T 28-03-2018 CDW54_RS02980 0247d54a3a5c2244400c228c94799622 178 SUPERFAMILY SSF46689 9 73 9.22E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDW54_RS11915 ae097c1a0550e4201caa5d62eafa1153 175 Pfam PF03729 Short repeat of unknown function (DUF308) 125 171 8.0E-8 T 28-03-2018 IPR005325 Protein of unknown function DUF308, membrane CDW54_RS11915 ae097c1a0550e4201caa5d62eafa1153 175 Pfam PF03729 Short repeat of unknown function (DUF308) 16 84 2.9E-7 T 28-03-2018 IPR005325 Protein of unknown function DUF308, membrane CDW54_RS04585 4aa060d727ed96893b54d35bf28bcdfd 589 SMART SM00382 375 561 1.7E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS04585 4aa060d727ed96893b54d35bf28bcdfd 589 Gene3D G3DSA:3.40.50.300 338 587 4.5E-74 T 28-03-2018 CDW54_RS04585 4aa060d727ed96893b54d35bf28bcdfd 589 SUPERFAMILY SSF90123 9 334 2.88E-70 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CDW54_RS04585 4aa060d727ed96893b54d35bf28bcdfd 589 SUPERFAMILY SSF52540 343 586 4.02E-90 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS04585 4aa060d727ed96893b54d35bf28bcdfd 589 Pfam PF00005 ABC transporter 366 515 7.9E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS04585 4aa060d727ed96893b54d35bf28bcdfd 589 Pfam PF00664 ABC transporter transmembrane region 23 302 4.2E-45 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CDW54_RS04585 4aa060d727ed96893b54d35bf28bcdfd 589 Gene3D G3DSA:1.20.1560.10 4 337 3.7E-68 T 28-03-2018 CDW54_RS10195 4b41d59996fad0fde5e531857cf03ffc 175 SUPERFAMILY SSF54403 112 172 3.23E-14 T 28-03-2018 CDW54_RS10195 4b41d59996fad0fde5e531857cf03ffc 175 Gene3D G3DSA:3.10.450.40 112 174 2.0E-11 T 28-03-2018 CDW54_RS10195 4b41d59996fad0fde5e531857cf03ffc 175 Gene3D G3DSA:3.10.450.40 45 107 3.2E-22 T 28-03-2018 CDW54_RS10195 4b41d59996fad0fde5e531857cf03ffc 175 SUPERFAMILY SSF54403 49 112 1.51E-18 T 28-03-2018 CDW54_RS05255 d8569f63ec3d447e660e85c6d96762d7 130 SUPERFAMILY SSF54211 6 130 2.47E-48 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CDW54_RS05255 d8569f63ec3d447e660e85c6d96762d7 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 28-03-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 CDW54_RS05255 d8569f63ec3d447e660e85c6d96762d7 130 Gene3D G3DSA:3.30.230.10 3 130 6.9E-53 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CDW54_RS05255 d8569f63ec3d447e660e85c6d96762d7 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 33.292 T 28-03-2018 IPR023035 Ribosomal protein S9, bacterial/plastid CDW54_RS05255 d8569f63ec3d447e660e85c6d96762d7 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 7.0E-48 T 28-03-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 CDW54_RS08550 5c461afb2e6dd9c4b222ab4572a5d529 625 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 590 621 1.2E-6 T 28-03-2018 CDW54_RS08550 5c461afb2e6dd9c4b222ab4572a5d529 625 Pfam PF00746 LPXTG cell wall anchor motif 585 622 1.9E-5 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CDW54_RS08550 5c461afb2e6dd9c4b222ab4572a5d529 625 Gene3D G3DSA:2.60.40.810 459 594 9.1E-19 T 28-03-2018 CDW54_RS08550 5c461afb2e6dd9c4b222ab4572a5d529 625 Gene3D G3DSA:2.60.40.10 56 190 2.4E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold CDW54_RS08550 5c461afb2e6dd9c4b222ab4572a5d529 625 Gene3D G3DSA:2.60.40.740 320 458 2.4E-17 T 28-03-2018 CDW54_RS08550 5c461afb2e6dd9c4b222ab4572a5d529 625 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 309 453 3.7E-15 T 28-03-2018 IPR026466 Fimbrial isopeptide formation D2 domain CDW54_RS08550 5c461afb2e6dd9c4b222ab4572a5d529 625 Gene3D G3DSA:2.60.40.10 191 319 9.3E-11 T 28-03-2018 IPR013783 Immunoglobulin-like fold CDW54_RS00680 6dadc623836b0a4475de4abd6210ade4 180 Hamap MF_01515 UPF0316 protein . 4 175 29.527 T 28-03-2018 IPR022930 Protein of unknown function UPF0316 CDW54_RS00680 6dadc623836b0a4475de4abd6210ade4 180 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 115 167 2.1E-7 T 28-03-2018 IPR019264 Domain of unknown function DUF2179 CDW54_RS04960 83673a72ddaa9935ee7b03b16df9f2af 189 Pfam PF09515 Thiamine transporter protein (Thia_YuaJ) 7 181 1.6E-60 T 28-03-2018 IPR012651 Thiamine transporter ThiT GO:0005886|GO:0015234|GO:0015888 CDW54_RS04960 83673a72ddaa9935ee7b03b16df9f2af 189 TIGRFAM TIGR02357 ECF_ThiT_YuaJ: energy-coupled thiamine transporter ThiT 5 183 1.8E-55 T 28-03-2018 IPR012651 Thiamine transporter ThiT GO:0005886|GO:0015234|GO:0015888 CDW54_RS00885 6697a0fde50b6ebc7d69dd7bf673ce11 291 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 10 213 1.1E-63 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT CDW54_RS00885 6697a0fde50b6ebc7d69dd7bf673ce11 291 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 221 275 2.8E-21 T 28-03-2018 IPR019264 Domain of unknown function DUF2179 CDW54_RS00885 6697a0fde50b6ebc7d69dd7bf673ce11 291 PIRSF PIRSF006483 1 282 4.2E-83 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT CDW54_RS11815 9ffc924c1912d9611c19ae824b7187f8 75 SUPERFAMILY SSF47413 1 70 1.46E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDW54_RS11815 9ffc924c1912d9611c19ae824b7187f8 75 SMART SM00530 6 62 6.7E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDW54_RS11815 9ffc924c1912d9611c19ae824b7187f8 75 Gene3D G3DSA:1.10.260.40 2 72 1.3E-11 T 28-03-2018 CDW54_RS11815 9ffc924c1912d9611c19ae824b7187f8 75 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 6 68 2.4E-23 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDW54_RS09005 fb823fa507aaa12be2d6a2091bc2f17c 126 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 124 7.9E-19 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CDW54_RS09005 fb823fa507aaa12be2d6a2091bc2f17c 126 SUPERFAMILY SSF54593 1 126 1.88E-31 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDW54_RS09005 fb823fa507aaa12be2d6a2091bc2f17c 126 Gene3D G3DSA:3.10.180.10 1 126 7.8E-28 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDW54_RS09005 fb823fa507aaa12be2d6a2091bc2f17c 126 ProSitePatterns PS00934 Glyoxalase I signature 1. 8 29 - T 28-03-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 CDW54_RS04790 21328a9e785d2ba81a2f65b8359cc5ad 181 SUPERFAMILY SSF53271 3 178 2.75E-61 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CDW54_RS04790 21328a9e785d2ba81a2f65b8359cc5ad 181 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 9 174 2.5E-68 T 28-03-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 CDW54_RS04790 21328a9e785d2ba81a2f65b8359cc5ad 181 Pfam PF00156 Phosphoribosyl transferase domain 16 160 5.7E-26 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CDW54_RS04790 21328a9e785d2ba81a2f65b8359cc5ad 181 Gene3D G3DSA:3.40.50.2020 1 181 2.5E-48 T 28-03-2018 CDW54_RS10675 33266f69e52f31b78cec959eca6a370b 172 PIRSF PIRSF000194 1 165 9.2E-43 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CDW54_RS10675 33266f69e52f31b78cec959eca6a370b 172 PRINTS PR00070 Dihydrofolate reductase signature 94 108 3.5E-13 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CDW54_RS10675 33266f69e52f31b78cec959eca6a370b 172 PRINTS PR00070 Dihydrofolate reductase signature 27 35 3.5E-13 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CDW54_RS10675 33266f69e52f31b78cec959eca6a370b 172 PRINTS PR00070 Dihydrofolate reductase signature 40 51 3.5E-13 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CDW54_RS10675 33266f69e52f31b78cec959eca6a370b 172 PRINTS PR00070 Dihydrofolate reductase signature 13 23 3.5E-13 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CDW54_RS10675 33266f69e52f31b78cec959eca6a370b 172 SUPERFAMILY SSF53597 1 163 5.74E-47 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CDW54_RS10675 33266f69e52f31b78cec959eca6a370b 172 Pfam PF00186 Dihydrofolate reductase 2 162 1.5E-50 T 28-03-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CDW54_RS10675 33266f69e52f31b78cec959eca6a370b 172 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 13 35 - T 28-03-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 CDW54_RS10675 33266f69e52f31b78cec959eca6a370b 172 Gene3D G3DSA:3.40.430.10 1 165 5.4E-40 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CDW54_RS04270 47c809e0c8cd5ac171d61223d12d3625 436 Gene3D G3DSA:2.160.20.10 15 431 1.5E-76 T 28-03-2018 IPR012334 Pectin lyase fold CDW54_RS04270 47c809e0c8cd5ac171d61223d12d3625 436 SMART SM00710 243 263 2600.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CDW54_RS04270 47c809e0c8cd5ac171d61223d12d3625 436 SMART SM00710 209 230 710.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CDW54_RS04270 47c809e0c8cd5ac171d61223d12d3625 436 SMART SM00710 269 290 1500.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CDW54_RS04270 47c809e0c8cd5ac171d61223d12d3625 436 SMART SM00710 183 208 1.1 T 28-03-2018 IPR006626 Parallel beta-helix repeat CDW54_RS04270 47c809e0c8cd5ac171d61223d12d3625 436 Pfam PF00295 Glycosyl hydrolases family 28 87 316 4.7E-29 T 28-03-2018 IPR000743 Glycoside hydrolase, family 28 GO:0004650|GO:0005975 CDW54_RS04270 47c809e0c8cd5ac171d61223d12d3625 436 SUPERFAMILY SSF51126 15 403 1.57E-67 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CDW54_RS07185 3a04d3eea55e9cc00c1e49f9947bce7c 479 Gene3D G3DSA:3.40.50.2300 394 479 1.1E-10 T 28-03-2018 CDW54_RS07185 3a04d3eea55e9cc00c1e49f9947bce7c 479 Pfam PF05043 Mga helix-turn-helix domain 78 163 2.9E-19 T 28-03-2018 IPR007737 Mga helix-turn-helix domain CDW54_RS07185 3a04d3eea55e9cc00c1e49f9947bce7c 479 Gene3D G3DSA:1.10.10.10 93 149 0.0018 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS07185 3a04d3eea55e9cc00c1e49f9947bce7c 479 Gene3D G3DSA:1.10.10.10 3 74 9.8E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS07185 3a04d3eea55e9cc00c1e49f9947bce7c 479 Pfam PF08279 HTH domain 19 67 7.4E-7 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CDW54_RS07290 13322b3f717e53e5bdfbbd72746d3dc1 201 Gene3D G3DSA:3.90.79.10 57 197 1.1E-21 T 28-03-2018 CDW54_RS07290 13322b3f717e53e5bdfbbd72746d3dc1 201 SUPERFAMILY SSF55811 62 192 1.76E-26 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CDW54_RS07290 13322b3f717e53e5bdfbbd72746d3dc1 201 PRINTS PR00502 NUDIX hydrolase family signature 105 120 2.9E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CDW54_RS07290 13322b3f717e53e5bdfbbd72746d3dc1 201 PRINTS PR00502 NUDIX hydrolase family signature 91 105 2.9E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CDW54_RS07290 13322b3f717e53e5bdfbbd72746d3dc1 201 Pfam PF00293 NUDIX domain 74 185 3.9E-15 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CDW54_RS07290 13322b3f717e53e5bdfbbd72746d3dc1 201 Pfam PF12535 Hydrolase of X-linked nucleoside diphosphate N terminal 3 56 3.2E-19 T 28-03-2018 CDW54_RS09575 f2de164db54341fb450dda8ce603cba8 251 ProSitePatterns PS00171 Triosephosphate isomerase active site. 165 175 - T 28-03-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDW54_RS09575 f2de164db54341fb450dda8ce603cba8 251 SUPERFAMILY SSF51351 1 249 4.45E-93 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDW54_RS09575 f2de164db54341fb450dda8ce603cba8 251 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 250 40.391 T 28-03-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDW54_RS09575 f2de164db54341fb450dda8ce603cba8 251 Gene3D G3DSA:3.20.20.70 1 251 4.6E-102 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDW54_RS09575 f2de164db54341fb450dda8ce603cba8 251 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 241 6.3E-58 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDW54_RS09575 f2de164db54341fb450dda8ce603cba8 251 Pfam PF00121 Triosephosphate isomerase 5 246 1.9E-94 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDW54_RS11975 56b410013b950bb2e3c38ec593dc90d2 144 SUPERFAMILY SSF54593 11 128 2.06E-15 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDW54_RS11975 56b410013b950bb2e3c38ec593dc90d2 144 Gene3D G3DSA:3.10.180.10 9 140 1.3E-11 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDW54_RS05310 23ada3bc90610afca7767ab75f648dc8 355 SUPERFAMILY SSF51735 133 271 9.02E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS05310 23ada3bc90610afca7767ab75f648dc8 355 Gene3D G3DSA:3.90.180.10 1 160 3.1E-15 T 28-03-2018 CDW54_RS05310 23ada3bc90610afca7767ab75f648dc8 355 SUPERFAMILY SSF50129 1 165 5.29E-9 T 28-03-2018 IPR011032 GroES-like CDW54_RS05310 23ada3bc90610afca7767ab75f648dc8 355 Gene3D G3DSA:3.40.50.720 161 284 1.3E-19 T 28-03-2018 CDW54_RS05310 23ada3bc90610afca7767ab75f648dc8 355 Pfam PF00107 Zinc-binding dehydrogenase 168 270 2.8E-24 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CDW54_RS08840 2b27f200c7eaa860cd87ad640ee75a3a 697 Pfam PF00884 Sulfatase 253 548 3.9E-34 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CDW54_RS08840 2b27f200c7eaa860cd87ad640ee75a3a 697 SUPERFAMILY SSF53649 251 650 9.91E-72 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CDW54_RS08840 2b27f200c7eaa860cd87ad640ee75a3a 697 PIRSF PIRSF005091 2 637 1.5E-212 T 28-03-2018 IPR012160 Lipoteichoic acid synthase-like CDW54_RS08840 2b27f200c7eaa860cd87ad640ee75a3a 697 Gene3D G3DSA:3.40.720.10 248 558 6.7E-36 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CDW54_RS06420 f4c4c24b2469867b7a23dfd6a7cd902f 450 Pfam PF05525 Branched-chain amino acid transport protein 8 441 1.8E-149 T 28-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CDW54_RS06420 f4c4c24b2469867b7a23dfd6a7cd902f 450 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 14 429 4.8E-124 T 28-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CDW54_RS05425 620a3714129cf02a109174189fc821ab 317 Pfam PF01040 UbiA prenyltransferase family 19 272 1.1E-23 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CDW54_RS05425 620a3714129cf02a109174189fc821ab 317 PIRSF PIRSF005355 173 316 5.0E-17 T 28-03-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 CDW54_RS05425 620a3714129cf02a109174189fc821ab 317 PIRSF PIRSF005355 1 181 1.5E-21 T 28-03-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 CDW54_RS05370 f8e6b6a7b0a0e697d8fe04b08266fa75 268 Pfam PF00005 ABC transporter 25 180 9.4E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS05370 f8e6b6a7b0a0e697d8fe04b08266fa75 268 Gene3D G3DSA:3.40.50.300 1 259 3.7E-53 T 28-03-2018 CDW54_RS05370 f8e6b6a7b0a0e697d8fe04b08266fa75 268 SUPERFAMILY SSF52540 2 236 1.92E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS05370 f8e6b6a7b0a0e697d8fe04b08266fa75 268 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS05370 f8e6b6a7b0a0e697d8fe04b08266fa75 268 SMART SM00382 34 229 3.3E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS09800 c6acaf14c1905e54a126348e787eda09 225 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 4 214 1.2E-76 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CDW54_RS09800 c6acaf14c1905e54a126348e787eda09 225 Gene3D G3DSA:1.20.58.220 112 225 2.6E-28 T 28-03-2018 CDW54_RS09800 c6acaf14c1905e54a126348e787eda09 225 SUPERFAMILY SSF109755 3 220 3.66E-66 T 28-03-2018 CDW54_RS09800 c6acaf14c1905e54a126348e787eda09 225 Pfam PF01895 PhoU domain 121 206 1.4E-19 T 28-03-2018 IPR026022 PhoU domain CDW54_RS09800 c6acaf14c1905e54a126348e787eda09 225 Pfam PF01895 PhoU domain 18 104 1.6E-21 T 28-03-2018 IPR026022 PhoU domain CDW54_RS09800 c6acaf14c1905e54a126348e787eda09 225 PIRSF PIRSF003107 1 220 7.1E-68 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CDW54_RS09800 c6acaf14c1905e54a126348e787eda09 225 Gene3D G3DSA:1.20.58.220 1 111 2.0E-25 T 28-03-2018 CDW54_RS00250 30e959db5d1c279d1de19e7b94c8cfee 186 SUPERFAMILY SSF53335 1 181 2.86E-51 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDW54_RS00250 30e959db5d1c279d1de19e7b94c8cfee 186 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 117 123 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CDW54_RS00250 30e959db5d1c279d1de19e7b94c8cfee 186 PIRSF PIRSF004553 1 183 1.7E-52 T 28-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 CDW54_RS00250 30e959db5d1c279d1de19e7b94c8cfee 186 Gene3D G3DSA:3.40.50.150 1 184 4.5E-35 T 28-03-2018 CDW54_RS00250 30e959db5d1c279d1de19e7b94c8cfee 186 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 2 182 8.7E-53 T 28-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 CDW54_RS00250 30e959db5d1c279d1de19e7b94c8cfee 186 Pfam PF03602 Conserved hypothetical protein 95 1 181 6.5E-62 T 28-03-2018 CDW54_RS03510 4b4b19057a4d7324fa64cb57f099110a 340 SUPERFAMILY SSF51004 10 337 7.32E-42 T 28-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain CDW54_RS03510 4b4b19057a4d7324fa64cb57f099110a 340 Gene3D G3DSA:2.130.10.10 1 340 9.7E-48 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CDW54_RS03510 4b4b19057a4d7324fa64cb57f099110a 340 Pfam PF10282 Lactonase, 7-bladed beta-propeller 5 338 1.8E-117 T 28-03-2018 IPR019405 Lactonase, 7-bladed beta propeller CDW54_RS07675 d3f92ca14c7e8fa01aaf7a625e910a6c 105 SUPERFAMILY SSF46785 11 100 5.82E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS07675 d3f92ca14c7e8fa01aaf7a625e910a6c 105 Pfam PF03551 Transcriptional regulator PadR-like family 14 83 5.0E-19 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CDW54_RS07675 d3f92ca14c7e8fa01aaf7a625e910a6c 105 Gene3D G3DSA:1.10.10.10 1 94 7.9E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS10085 579934310e94dd5a5a9a172d84c72cfa 470 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 326 459 9.9E-16 T 28-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CDW54_RS10085 579934310e94dd5a5a9a172d84c72cfa 470 Pfam PF01943 Polysaccharide biosynthesis protein 5 267 4.2E-21 T 28-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CDW54_RS08280 e76333c8903057777644d5884625dad1 347 Pfam PF03601 Conserved hypothetical protein 698 21 326 2.2E-68 T 28-03-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 CDW54_RS09470 5ae06d38dc409c5c64f745f4f0f985f2 211 TIGRFAM TIGR00309 V_ATPase_subD: V-type ATPase, D subunit 5 206 9.4E-50 T 28-03-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CDW54_RS09470 5ae06d38dc409c5c64f745f4f0f985f2 211 Pfam PF01813 ATP synthase subunit D 12 205 4.7E-58 T 28-03-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CDW54_RS09470 5ae06d38dc409c5c64f745f4f0f985f2 211 Gene3D G3DSA:1.20.5.340 3 136 9.9E-4 T 28-03-2018 CDW54_RS09470 5ae06d38dc409c5c64f745f4f0f985f2 211 Hamap MF_00271 V-type ATP synthase subunit D [atpD]. 3 211 22.185 T 28-03-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CDW54_RS09745 5e1c8d4ea361ac23f7c3918c1ec085af 183 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 125 179 7.5E-27 T 28-03-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal CDW54_RS09745 5e1c8d4ea361ac23f7c3918c1ec085af 183 Gene3D G3DSA:3.30.160.100 1 103 4.8E-32 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CDW54_RS09745 5e1c8d4ea361ac23f7c3918c1ec085af 183 SUPERFAMILY SSF69754 4 106 3.01E-32 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CDW54_RS09745 5e1c8d4ea361ac23f7c3918c1ec085af 183 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 4 96 7.1E-31 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CDW54_RS09745 5e1c8d4ea361ac23f7c3918c1ec085af 183 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 2 183 25.246 T 28-03-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid CDW54_RS09745 5e1c8d4ea361ac23f7c3918c1ec085af 183 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 4 102 2.6E-31 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CDW54_RS00275 c3ca971b8d293bc2bd02f4e99622f244 387 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 338 362 - T 28-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 CDW54_RS00275 c3ca971b8d293bc2bd02f4e99622f244 387 Pfam PF01098 Cell cycle protein 15 381 1.6E-88 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CDW54_RS00275 c3ca971b8d293bc2bd02f4e99622f244 387 Gene3D G3DSA:1.20.1250.20 132 385 0.031 T 28-03-2018 CDW54_RS00275 c3ca971b8d293bc2bd02f4e99622f244 387 Gene3D G3DSA:1.20.1250.20 3 116 0.17 T 28-03-2018 CDW54_RS01650 92690fe920eee753f9cb65ce36147e1b 372 Pfam PF01594 AI-2E family transporter 18 351 1.1E-86 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like CDW54_RS10455 0b5e428173dbcc4fc26b11340fe161fe 289 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 281 1.6E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS10455 0b5e428173dbcc4fc26b11340fe161fe 289 Gene3D G3DSA:1.10.3720.10 11 276 7.9E-40 T 28-03-2018 CDW54_RS10455 0b5e428173dbcc4fc26b11340fe161fe 289 SUPERFAMILY SSF161098 22 288 2.15E-70 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS06705 b4742d6ef10b1420e1a1975d90420c7b 342 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 47 325 2.1E-72 T 28-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CDW54_RS06705 b4742d6ef10b1420e1a1975d90420c7b 342 Gene3D G3DSA:3.40.190.10 156 247 6.6E-5 T 28-03-2018 CDW54_RS06705 b4742d6ef10b1420e1a1975d90420c7b 342 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 48 291 3.8E-62 T 28-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 CDW54_RS06705 b4742d6ef10b1420e1a1975d90420c7b 342 Gene3D G3DSA:3.40.190.10 1 155 2.1E-7 T 28-03-2018 CDW54_RS06705 b4742d6ef10b1420e1a1975d90420c7b 342 SUPERFAMILY SSF53850 169 220 1.58E-5 T 28-03-2018 CDW54_RS06705 b4742d6ef10b1420e1a1975d90420c7b 342 SUPERFAMILY SSF53850 60 135 1.58E-5 T 28-03-2018 CDW54_RS06705 b4742d6ef10b1420e1a1975d90420c7b 342 PIRSF PIRSF006470 14 342 1.1E-72 T 28-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 CDW54_RS04135 c5fddd1e4db873f43d9106f8c13257e8 527 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS04135 c5fddd1e4db873f43d9106f8c13257e8 527 Pfam PF00005 ABC transporter 344 471 3.5E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS04135 c5fddd1e4db873f43d9106f8c13257e8 527 Pfam PF00005 ABC transporter 19 187 3.4E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS04135 c5fddd1e4db873f43d9106f8c13257e8 527 Gene3D G3DSA:3.40.50.300 3 287 3.5E-49 T 28-03-2018 CDW54_RS04135 c5fddd1e4db873f43d9106f8c13257e8 527 SUPERFAMILY SSF52540 324 517 1.68E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS04135 c5fddd1e4db873f43d9106f8c13257e8 527 SUPERFAMILY SSF52540 6 236 8.46E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS04135 c5fddd1e4db873f43d9106f8c13257e8 527 Pfam PF12848 ABC transporter 226 309 9.2E-20 T 28-03-2018 IPR032781 ABC-transporter extension domain CDW54_RS04135 c5fddd1e4db873f43d9106f8c13257e8 527 Gene3D G3DSA:3.40.50.300 290 522 3.6E-46 T 28-03-2018 CDW54_RS04135 c5fddd1e4db873f43d9106f8c13257e8 527 SMART SM00382 352 522 1.3E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS04135 c5fddd1e4db873f43d9106f8c13257e8 527 SMART SM00382 27 253 5.7E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS07025 b75bc83387bd30ecaba9d2326584514a 236 Pfam PF15983 Domain of unknown function (DUF4767) 96 231 1.0E-50 T 28-03-2018 IPR031927 Domain of unknown function DUF4767 CDW54_RS09105 6498d8888a2ee70d082b862e7a65a530 302 Pfam PF01609 Transposase DDE domain 115 281 2.8E-23 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDW54_RS10410 b12f919889de97c8368a84c0263ddaa1 173 Pfam PF01782 RimM N-terminal domain 7 89 1.4E-21 T 28-03-2018 IPR002676 RimM protein GO:0006364 CDW54_RS10410 b12f919889de97c8368a84c0263ddaa1 173 Pfam PF05239 PRC-barrel domain 96 168 2.8E-10 T 28-03-2018 IPR027275 PRC-barrel domain CDW54_RS10410 b12f919889de97c8368a84c0263ddaa1 173 SUPERFAMILY SSF50346 99 168 3.14E-18 T 28-03-2018 IPR011033 PRC-barrel-like CDW54_RS10410 b12f919889de97c8368a84c0263ddaa1 173 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 4 168 23.455 T 28-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 CDW54_RS10410 b12f919889de97c8368a84c0263ddaa1 173 Gene3D G3DSA:2.40.30.60 2 94 8.0E-24 T 28-03-2018 IPR002676 RimM protein GO:0006364 CDW54_RS10410 b12f919889de97c8368a84c0263ddaa1 173 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 5 168 1.8E-47 T 28-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 CDW54_RS10410 b12f919889de97c8368a84c0263ddaa1 173 SUPERFAMILY SSF50447 3 89 7.06E-20 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CDW54_RS10410 b12f919889de97c8368a84c0263ddaa1 173 Gene3D G3DSA:2.30.30.240 95 163 1.0E-19 T 28-03-2018 CDW54_RS00165 b0b6aba8c801230c1dcf4f74b326d2ec 163 SUPERFAMILY SSF89963 6 89 1.31E-27 T 28-03-2018 IPR007551 Protein of unknown function DUF520 CDW54_RS00165 b0b6aba8c801230c1dcf4f74b326d2ec 163 Gene3D G3DSA:3.30.70.860 99 163 1.8E-31 T 28-03-2018 IPR035571 UPF0234/UPF0381 domain CDW54_RS00165 b0b6aba8c801230c1dcf4f74b326d2ec 163 Gene3D G3DSA:3.30.70.990 13 98 2.7E-27 T 28-03-2018 IPR035570 UPF0234 N-terminal domain CDW54_RS00165 b0b6aba8c801230c1dcf4f74b326d2ec 163 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 4 163 25.574 T 28-03-2018 IPR007551 Protein of unknown function DUF520 CDW54_RS00165 b0b6aba8c801230c1dcf4f74b326d2ec 163 SUPERFAMILY SSF89963 92 163 1.8E-27 T 28-03-2018 IPR007551 Protein of unknown function DUF520 CDW54_RS00165 b0b6aba8c801230c1dcf4f74b326d2ec 163 Pfam PF04461 Protein of unknown function (DUF520) 6 163 1.1E-61 T 28-03-2018 IPR007551 Protein of unknown function DUF520 CDW54_RS11075 abc98b5ad31932c43ca028d80e533e96 389 Pfam PF07949 YbbR-like protein 148 224 3.3E-7 T 28-03-2018 IPR012505 YbbR-like CDW54_RS11075 abc98b5ad31932c43ca028d80e533e96 389 Pfam PF07949 YbbR-like protein 240 312 6.0E-5 T 28-03-2018 IPR012505 YbbR-like CDW54_RS11075 abc98b5ad31932c43ca028d80e533e96 389 Pfam PF07949 YbbR-like protein 49 132 6.4E-10 T 28-03-2018 IPR012505 YbbR-like CDW54_RS08655 3e9708f57b961a37408bcc170e729701 217 Gene3D G3DSA:3.40.50.300 1 217 9.5E-66 T 28-03-2018 CDW54_RS08655 3e9708f57b961a37408bcc170e729701 217 SMART SM00382 30 211 1.7E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS08655 3e9708f57b961a37408bcc170e729701 217 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS08655 3e9708f57b961a37408bcc170e729701 217 Pfam PF00005 ABC transporter 21 164 5.5E-37 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS08655 3e9708f57b961a37408bcc170e729701 217 SUPERFAMILY SSF52540 4 215 6.37E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS03075 5ee980fb9c3fc6394a0fb9c9f9523fac 339 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 182 321 2.0E-53 T 28-03-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CDW54_RS03075 5ee980fb9c3fc6394a0fb9c9f9523fac 339 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 190 211 - T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CDW54_RS03075 5ee980fb9c3fc6394a0fb9c9f9523fac 339 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 3 324 37.738 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CDW54_RS03075 5ee980fb9c3fc6394a0fb9c9f9523fac 339 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 7 24 6.8E-48 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CDW54_RS03075 5ee980fb9c3fc6394a0fb9c9f9523fac 339 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 135 155 6.8E-48 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CDW54_RS03075 5ee980fb9c3fc6394a0fb9c9f9523fac 339 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 175 199 6.8E-48 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CDW54_RS03075 5ee980fb9c3fc6394a0fb9c9f9523fac 339 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 57 84 6.8E-48 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CDW54_RS03075 5ee980fb9c3fc6394a0fb9c9f9523fac 339 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 200 224 6.8E-48 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CDW54_RS03075 5ee980fb9c3fc6394a0fb9c9f9523fac 339 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 240 257 6.8E-48 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CDW54_RS03075 5ee980fb9c3fc6394a0fb9c9f9523fac 339 SUPERFAMILY SSF48179 181 333 3.23E-56 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CDW54_RS03075 5ee980fb9c3fc6394a0fb9c9f9523fac 339 PIRSF PIRSF000114 1 334 5.7E-106 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CDW54_RS03075 5ee980fb9c3fc6394a0fb9c9f9523fac 339 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 4 162 6.8E-56 T 28-03-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CDW54_RS03075 5ee980fb9c3fc6394a0fb9c9f9523fac 339 Gene3D G3DSA:3.40.50.720 1 181 3.5E-40 T 28-03-2018 CDW54_RS03075 5ee980fb9c3fc6394a0fb9c9f9523fac 339 SUPERFAMILY SSF51735 4 180 1.57E-59 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS03075 5ee980fb9c3fc6394a0fb9c9f9523fac 339 Gene3D G3DSA:1.10.1040.10 191 338 1.6E-53 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CDW54_RS03780 64846bfebbe813492982175c16944400 74 TIGRFAM TIGR02194 GlrX_NrdH: glutaredoxin-like protein NrdH 3 73 4.5E-36 T 28-03-2018 IPR011909 Glutaredoxin-like protein NrdH GO:0045454 CDW54_RS03780 64846bfebbe813492982175c16944400 74 Gene3D G3DSA:3.40.30.10 1 74 2.9E-17 T 28-03-2018 CDW54_RS03780 64846bfebbe813492982175c16944400 74 SUPERFAMILY SSF52833 1 72 3.33E-20 T 28-03-2018 IPR012336 Thioredoxin-like fold CDW54_RS03780 64846bfebbe813492982175c16944400 74 Pfam PF00462 Glutaredoxin 3 57 4.5E-15 T 28-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 CDW54_RS10580 590cf1e146fbf89ddf5cddbeebf94540 417 Pfam PF03486 HI0933-like protein 5 411 6.2E-141 T 28-03-2018 CDW54_RS10580 590cf1e146fbf89ddf5cddbeebf94540 417 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 9.6E-9 T 28-03-2018 CDW54_RS10580 590cf1e146fbf89ddf5cddbeebf94540 417 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 160 169 9.6E-9 T 28-03-2018 CDW54_RS10580 590cf1e146fbf89ddf5cddbeebf94540 417 SUPERFAMILY SSF51905 5 195 3.39E-56 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS10580 590cf1e146fbf89ddf5cddbeebf94540 417 SUPERFAMILY SSF51905 356 413 3.39E-56 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS10580 590cf1e146fbf89ddf5cddbeebf94540 417 SUPERFAMILY SSF160996 196 359 1.07E-38 T 28-03-2018 CDW54_RS10580 590cf1e146fbf89ddf5cddbeebf94540 417 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 9.4E-5 T 28-03-2018 CDW54_RS10580 590cf1e146fbf89ddf5cddbeebf94540 417 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 157 175 9.4E-5 T 28-03-2018 CDW54_RS10580 590cf1e146fbf89ddf5cddbeebf94540 417 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 7 411 1.2E-138 T 28-03-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like CDW54_RS10580 590cf1e146fbf89ddf5cddbeebf94540 417 Gene3D G3DSA:3.50.50.60 4 417 4.1E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS07695 b30c139e23a8468cab97ba2f4c2fc8e4 290 Pfam PF01145 SPFH domain / Band 7 family 60 232 1.3E-24 T 28-03-2018 IPR001107 Band 7 domain CDW54_RS07695 b30c139e23a8468cab97ba2f4c2fc8e4 290 SMART SM00244 56 220 1.7E-10 T 28-03-2018 IPR001107 Band 7 domain CDW54_RS07695 b30c139e23a8468cab97ba2f4c2fc8e4 290 SUPERFAMILY SSF117892 92 223 2.62E-13 T 28-03-2018 IPR001107 Band 7 domain CDW54_RS04310 76aa3ece2f5147b17c4a6274f3693da2 367 SUPERFAMILY SSF48208 23 365 8.32E-70 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CDW54_RS04310 76aa3ece2f5147b17c4a6274f3693da2 367 Gene3D G3DSA:1.50.10.10 1 367 5.7E-77 T 28-03-2018 CDW54_RS04310 76aa3ece2f5147b17c4a6274f3693da2 367 Pfam PF07470 Glycosyl Hydrolase Family 88 4 365 8.6E-93 T 28-03-2018 IPR010905 Glycosyl hydrolase, family 88 CDW54_RS11325 02dd42e740148b1780d31b3c5fe2862a 295 SUPERFAMILY SSF161098 25 291 1.5E-57 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS11325 02dd42e740148b1780d31b3c5fe2862a 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 290 4.3E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS11325 02dd42e740148b1780d31b3c5fe2862a 295 Gene3D G3DSA:1.10.3720.10 20 284 4.0E-38 T 28-03-2018 CDW54_RS08950 fb3d336838b11ab9f7bb4e81dec44e10 148 Gene3D G3DSA:3.40.50.360 1 148 1.7E-20 T 28-03-2018 IPR029039 Flavoprotein-like domain CDW54_RS08950 fb3d336838b11ab9f7bb4e81dec44e10 148 Pfam PF07972 NrdI Flavodoxin like 3 141 8.3E-41 T 28-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI CDW54_RS08950 fb3d336838b11ab9f7bb4e81dec44e10 148 PIRSF PIRSF005087 1 148 5.4E-39 T 28-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI CDW54_RS08950 fb3d336838b11ab9f7bb4e81dec44e10 148 SUPERFAMILY SSF52218 2 144 2.79E-20 T 28-03-2018 IPR029039 Flavoprotein-like domain CDW54_RS02580 1251cb953361ecc853db7020792593da 403 SMART SM00981 74 165 6.2E-22 T 28-03-2018 IPR004114 THUMP domain GO:0003723 CDW54_RS02580 1251cb953361ecc853db7020792593da 403 SUPERFAMILY SSF143437 3 173 2.44E-52 T 28-03-2018 CDW54_RS02580 1251cb953361ecc853db7020792593da 403 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 6 372 1.0E-115 T 28-03-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 CDW54_RS02580 1251cb953361ecc853db7020792593da 403 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 403 159.159 T 28-03-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 CDW54_RS02580 1251cb953361ecc853db7020792593da 403 Gene3D G3DSA:3.40.50.620 175 403 2.5E-35 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDW54_RS02580 1251cb953361ecc853db7020792593da 403 Pfam PF02926 THUMP domain 58 163 3.9E-17 T 28-03-2018 IPR004114 THUMP domain GO:0003723 CDW54_RS02580 1251cb953361ecc853db7020792593da 403 SUPERFAMILY SSF52402 174 381 6.4E-45 T 28-03-2018 CDW54_RS02580 1251cb953361ecc853db7020792593da 403 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 175 369 3.4E-60 T 28-03-2018 IPR020536 Thil, AANH domain GO:0004810 CDW54_RS02580 1251cb953361ecc853db7020792593da 403 Gene3D G3DSA:3.30.70.1510 5 81 3.0E-24 T 28-03-2018 CDW54_RS02580 1251cb953361ecc853db7020792593da 403 Gene3D G3DSA:3.30.2300.10 83 162 6.2E-18 T 28-03-2018 CDW54_RS03140 e908a27f61ce4b634fed4087643c7a93 140 SMART SM00851 14 107 1.2E-22 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CDW54_RS03140 e908a27f61ce4b634fed4087643c7a93 140 ProSitePatterns PS01335 Methylglyoxal synthase active site. 54 62 - T 28-03-2018 IPR018148 Methylglyoxal synthase, active site GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 CDW54_RS03140 e908a27f61ce4b634fed4087643c7a93 140 Pfam PF02142 MGS-like domain 15 107 3.0E-19 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CDW54_RS03140 e908a27f61ce4b634fed4087643c7a93 140 TIGRFAM TIGR00160 MGSA: methylglyoxal synthase 1 120 1.2E-56 T 28-03-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 CDW54_RS03140 e908a27f61ce4b634fed4087643c7a93 140 Gene3D G3DSA:3.40.50.1380 1 133 5.7E-35 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CDW54_RS03140 e908a27f61ce4b634fed4087643c7a93 140 SUPERFAMILY SSF52335 1 130 1.14E-50 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CDW54_RS03140 e908a27f61ce4b634fed4087643c7a93 140 PIRSF PIRSF006614 1 137 4.2E-58 T 28-03-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 CDW54_RS03140 e908a27f61ce4b634fed4087643c7a93 140 Hamap MF_00549 Methylglyoxal synthase [mgsA]. 1 120 35.549 T 28-03-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 CDW54_RS04950 b1c390b5b9344db08c31e2aae6c0fd84 566 Pfam PF01734 Patatin-like phospholipase 138 323 3.2E-27 T 28-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CDW54_RS04950 b1c390b5b9344db08c31e2aae6c0fd84 566 SUPERFAMILY SSF52151 136 427 2.62E-40 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CDW54_RS04950 b1c390b5b9344db08c31e2aae6c0fd84 566 Gene3D G3DSA:3.40.1090.10 125 387 2.3E-30 T 28-03-2018 CDW54_RS04990 b3d50d019df088e2ab0e5bb31954575b 312 PRINTS PR00690 Adhesin family signature 76 93 1.6E-13 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CDW54_RS04990 b3d50d019df088e2ab0e5bb31954575b 312 PRINTS PR00690 Adhesin family signature 197 218 1.6E-13 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CDW54_RS04990 b3d50d019df088e2ab0e5bb31954575b 312 PRINTS PR00690 Adhesin family signature 32 50 1.6E-13 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CDW54_RS04990 b3d50d019df088e2ab0e5bb31954575b 312 PRINTS PR00690 Adhesin family signature 63 76 1.6E-13 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CDW54_RS04990 b3d50d019df088e2ab0e5bb31954575b 312 PRINTS PR00690 Adhesin family signature 250 268 1.6E-13 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CDW54_RS04990 b3d50d019df088e2ab0e5bb31954575b 312 Pfam PF01297 Zinc-uptake complex component A periplasmic 35 309 5.4E-81 T 28-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 CDW54_RS04990 b3d50d019df088e2ab0e5bb31954575b 312 Gene3D G3DSA:3.40.50.1980 192 312 9.8E-40 T 28-03-2018 CDW54_RS04990 b3d50d019df088e2ab0e5bb31954575b 312 PRINTS PR00691 Adhesin B signature 57 75 1.3E-17 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CDW54_RS04990 b3d50d019df088e2ab0e5bb31954575b 312 PRINTS PR00691 Adhesin B signature 76 95 1.3E-17 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CDW54_RS04990 b3d50d019df088e2ab0e5bb31954575b 312 PRINTS PR00691 Adhesin B signature 290 308 1.3E-17 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CDW54_RS04990 b3d50d019df088e2ab0e5bb31954575b 312 PRINTS PR00691 Adhesin B signature 32 53 1.3E-17 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CDW54_RS04990 b3d50d019df088e2ab0e5bb31954575b 312 PRINTS PR00691 Adhesin B signature 246 263 1.3E-17 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CDW54_RS04990 b3d50d019df088e2ab0e5bb31954575b 312 PRINTS PR00691 Adhesin B signature 141 160 1.3E-17 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CDW54_RS04990 b3d50d019df088e2ab0e5bb31954575b 312 PRINTS PR00691 Adhesin B signature 197 214 1.3E-17 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CDW54_RS04990 b3d50d019df088e2ab0e5bb31954575b 312 Gene3D G3DSA:3.40.50.1980 21 191 2.6E-58 T 28-03-2018 CDW54_RS04990 b3d50d019df088e2ab0e5bb31954575b 312 SUPERFAMILY SSF53807 15 311 1.37E-87 T 28-03-2018 CDW54_RS00770 b0eb6d294b23b7e4bef36c0908339270 285 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 70 282 1.8E-71 T 28-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 CDW54_RS00770 b0eb6d294b23b7e4bef36c0908339270 285 Gene3D G3DSA:3.40.50.450 107 259 2.4E-36 T 28-03-2018 CDW54_RS00770 b0eb6d294b23b7e4bef36c0908339270 285 Pfam PF02481 DNA recombination-mediator protein A 72 272 6.1E-74 T 28-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 CDW54_RS00770 b0eb6d294b23b7e4bef36c0908339270 285 SUPERFAMILY SSF102405 77 283 3.21E-38 T 28-03-2018 CDW54_RS05390 09918b5a6685422733992927d561b021 669 TIGRFAM TIGR04215 choice_anch_A: choice-of-anchor A domain 53 313 3.1E-16 T 28-03-2018 IPR026588 Choice-of-anchor A domain CDW54_RS05390 09918b5a6685422733992927d561b021 669 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 634 668 1.5E-7 T 28-03-2018 CDW54_RS05390 09918b5a6685422733992927d561b021 669 Pfam PF00746 LPXTG cell wall anchor motif 628 657 5.8E-6 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CDW54_RS05115 ca4c07e51156c8a3892abaf8dd7ab723 268 SUPERFAMILY SSF53633 9 264 4.84E-63 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CDW54_RS05115 ca4c07e51156c8a3892abaf8dd7ab723 268 PRINTS PR00474 Glutamate 5-kinase family signature 46 60 3.1E-51 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CDW54_RS05115 ca4c07e51156c8a3892abaf8dd7ab723 268 PRINTS PR00474 Glutamate 5-kinase family signature 120 141 3.1E-51 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CDW54_RS05115 ca4c07e51156c8a3892abaf8dd7ab723 268 PRINTS PR00474 Glutamate 5-kinase family signature 217 237 3.1E-51 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CDW54_RS05115 ca4c07e51156c8a3892abaf8dd7ab723 268 PRINTS PR00474 Glutamate 5-kinase family signature 80 108 3.1E-51 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CDW54_RS05115 ca4c07e51156c8a3892abaf8dd7ab723 268 PRINTS PR00474 Glutamate 5-kinase family signature 156 183 3.1E-51 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CDW54_RS05115 ca4c07e51156c8a3892abaf8dd7ab723 268 Hamap MF_00456 Glutamate 5-kinase [proB]. 9 268 35.899 T 28-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CDW54_RS05115 ca4c07e51156c8a3892abaf8dd7ab723 268 Gene3D G3DSA:3.40.1160.10 1 268 2.0E-56 T 28-03-2018 CDW54_RS05115 ca4c07e51156c8a3892abaf8dd7ab723 268 TIGRFAM TIGR01027 proB: glutamate 5-kinase 9 265 4.8E-88 T 28-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CDW54_RS05115 ca4c07e51156c8a3892abaf8dd7ab723 268 ProSitePatterns PS00902 Glutamate 5-kinase signature. 215 232 - T 28-03-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CDW54_RS05115 ca4c07e51156c8a3892abaf8dd7ab723 268 Pfam PF00696 Amino acid kinase family 9 236 1.1E-34 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CDW54_RS05115 ca4c07e51156c8a3892abaf8dd7ab723 268 PIRSF PIRSF000729 4 268 1.8E-91 T 28-03-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 CDW54_RS10890 157363153b1b0102913b65c3276fae5f 115 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 1 114 1.3E-31 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CDW54_RS10890 157363153b1b0102913b65c3276fae5f 115 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 8 96 7.0E-45 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CDW54_RS10890 157363153b1b0102913b65c3276fae5f 115 Gene3D G3DSA:3.30.300.20 3 115 2.1E-32 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CDW54_RS10890 157363153b1b0102913b65c3276fae5f 115 Pfam PF02033 Ribosome-binding factor A 5 109 6.3E-31 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CDW54_RS10890 157363153b1b0102913b65c3276fae5f 115 ProSitePatterns PS01319 Ribosome-binding factor A signature. 75 96 - T 28-03-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 CDW54_RS10890 157363153b1b0102913b65c3276fae5f 115 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 1 115 20.151 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CDW54_RS10890 157363153b1b0102913b65c3276fae5f 115 SUPERFAMILY SSF89919 1 112 4.32E-32 T 28-03-2018 IPR023799 Ribosome-binding factor A domain CDW54_RS03490 0ce4d45cd93d364f997262c22a17bd5e 98 SMART SM00450 5 98 0.0065 T 28-03-2018 IPR001763 Rhodanese-like domain CDW54_RS03490 0ce4d45cd93d364f997262c22a17bd5e 98 Gene3D G3DSA:3.40.250.10 1 98 6.9E-15 T 28-03-2018 IPR001763 Rhodanese-like domain CDW54_RS03490 0ce4d45cd93d364f997262c22a17bd5e 98 Pfam PF00581 Rhodanese-like domain 16 95 1.4E-6 T 28-03-2018 IPR001763 Rhodanese-like domain CDW54_RS03490 0ce4d45cd93d364f997262c22a17bd5e 98 SUPERFAMILY SSF52821 3 95 1.37E-15 T 28-03-2018 IPR001763 Rhodanese-like domain CDW54_RS08925 fc78ba210e901931cc9230e3ab61eaca 500 SUPERFAMILY SSF52540 4 216 1.11E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS08925 fc78ba210e901931cc9230e3ab61eaca 500 Pfam PF00005 ABC transporter 23 145 1.5E-15 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS08925 fc78ba210e901931cc9230e3ab61eaca 500 Pfam PF00005 ABC transporter 331 456 9.1E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS08925 fc78ba210e901931cc9230e3ab61eaca 500 Gene3D G3DSA:3.40.50.300 291 499 4.5E-34 T 28-03-2018 CDW54_RS08925 fc78ba210e901931cc9230e3ab61eaca 500 SMART SM00382 338 496 0.18 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS08925 fc78ba210e901931cc9230e3ab61eaca 500 SMART SM00382 34 190 0.23 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS08925 fc78ba210e901931cc9230e3ab61eaca 500 ProSitePatterns PS00211 ABC transporters family signature. 117 131 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS08925 fc78ba210e901931cc9230e3ab61eaca 500 SUPERFAMILY SSF52540 300 498 1.26E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS08925 fc78ba210e901931cc9230e3ab61eaca 500 Gene3D G3DSA:3.40.50.300 1 290 3.3E-39 T 28-03-2018 CDW54_RS07265 94bd023a1f73cf5336f85e8dc494f958 429 Pfam PF03611 PTS system sugar-specific permease component 10 410 1.1E-122 T 28-03-2018 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 CDW54_RS06410 86f115f0761660c3fea05f0044d7cea1 160 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 81 96 4.1E-18 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CDW54_RS06410 86f115f0761660c3fea05f0044d7cea1 160 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 47 63 4.1E-18 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CDW54_RS06410 86f115f0761660c3fea05f0044d7cea1 160 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 104 117 4.1E-18 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CDW54_RS06410 86f115f0761660c3fea05f0044d7cea1 160 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 4 21 4.1E-18 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CDW54_RS06410 86f115f0761660c3fea05f0044d7cea1 160 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 123 138 4.1E-18 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CDW54_RS06410 86f115f0761660c3fea05f0044d7cea1 160 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 146 1.2E-37 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CDW54_RS06410 86f115f0761660c3fea05f0044d7cea1 160 Gene3D G3DSA:3.40.50.2300 1 156 8.0E-46 T 28-03-2018 CDW54_RS06410 86f115f0761660c3fea05f0044d7cea1 160 SUPERFAMILY SSF52788 1 149 5.23E-46 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CDW54_RS06410 86f115f0761660c3fea05f0044d7cea1 160 SMART SM00226 2 149 1.1E-44 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CDW54_RS01715 75a3ff2e7895ce996c1a800467d2f9eb 202 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 2 90 1.2E-33 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CDW54_RS01715 75a3ff2e7895ce996c1a800467d2f9eb 202 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 97 197 5.2E-43 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CDW54_RS01715 75a3ff2e7895ce996c1a800467d2f9eb 202 SUPERFAMILY SSF46609 1 91 6.02E-39 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CDW54_RS01715 75a3ff2e7895ce996c1a800467d2f9eb 202 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 2.3E-28 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CDW54_RS01715 75a3ff2e7895ce996c1a800467d2f9eb 202 PRINTS PR01703 Manganese superoxide dismutase signature 126 134 2.3E-28 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CDW54_RS01715 75a3ff2e7895ce996c1a800467d2f9eb 202 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 2.3E-28 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CDW54_RS01715 75a3ff2e7895ce996c1a800467d2f9eb 202 PRINTS PR01703 Manganese superoxide dismutase signature 162 174 2.3E-28 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CDW54_RS01715 75a3ff2e7895ce996c1a800467d2f9eb 202 PRINTS PR01703 Manganese superoxide dismutase signature 73 86 2.3E-28 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CDW54_RS01715 75a3ff2e7895ce996c1a800467d2f9eb 202 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 164 171 - T 28-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CDW54_RS01715 75a3ff2e7895ce996c1a800467d2f9eb 202 PIRSF PIRSF000349 1 202 2.5E-88 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CDW54_RS01715 75a3ff2e7895ce996c1a800467d2f9eb 202 Gene3D G3DSA:1.10.287.990 20 90 1.4E-31 T 28-03-2018 CDW54_RS01715 75a3ff2e7895ce996c1a800467d2f9eb 202 SUPERFAMILY SSF54719 92 201 3.14E-48 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CDW54_RS05630 ef391d9bc719e5da65ad842cd0ed24ad 631 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 7 626 42.188 T 28-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 CDW54_RS05630 ef391d9bc719e5da65ad842cd0ed24ad 631 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 371 394 - T 28-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 CDW54_RS05630 ef391d9bc719e5da65ad842cd0ed24ad 631 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 140 149 3.4E-6 T 28-03-2018 CDW54_RS05630 ef391d9bc719e5da65ad842cd0ed24ad 631 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 3.4E-6 T 28-03-2018 CDW54_RS05630 ef391d9bc719e5da65ad842cd0ed24ad 631 Pfam PF13932 GidA associated domain 404 618 1.9E-79 T 28-03-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 CDW54_RS05630 ef391d9bc719e5da65ad842cd0ed24ad 631 SUPERFAMILY SSF51905 99 264 8.04E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS05630 ef391d9bc719e5da65ad842cd0ed24ad 631 SUPERFAMILY SSF51905 9 68 8.04E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS05630 ef391d9bc719e5da65ad842cd0ed24ad 631 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 9 623 5.4E-283 T 28-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 CDW54_RS05630 ef391d9bc719e5da65ad842cd0ed24ad 631 Pfam PF01134 Glucose inhibited division protein A 10 402 2.2E-166 T 28-03-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 CDW54_RS05630 ef391d9bc719e5da65ad842cd0ed24ad 631 Gene3D G3DSA:3.50.50.60 7 268 2.7E-68 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDW54_RS05630 ef391d9bc719e5da65ad842cd0ed24ad 631 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 276 290 - T 28-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 CDW54_RS05630 ef391d9bc719e5da65ad842cd0ed24ad 631 SMART SM01228 548 619 4.7E-43 T 28-03-2018 CDW54_RS04495 57a86a7c22b80e412a5e886188000466 659 SUPERFAMILY SSF63520 296 397 3.92E-21 T 28-03-2018 IPR011608 PRD domain GO:0006355 CDW54_RS04495 57a86a7c22b80e412a5e886188000466 659 Pfam PF00874 PRD domain 305 393 4.3E-20 T 28-03-2018 IPR011608 PRD domain GO:0006355 CDW54_RS04495 57a86a7c22b80e412a5e886188000466 659 Pfam PF00874 PRD domain 208 286 7.5E-14 T 28-03-2018 IPR011608 PRD domain GO:0006355 CDW54_RS04495 57a86a7c22b80e412a5e886188000466 659 Gene3D G3DSA:1.10.1790.10 287 398 2.5E-23 T 28-03-2018 IPR011608 PRD domain GO:0006355 CDW54_RS04495 57a86a7c22b80e412a5e886188000466 659 Gene3D G3DSA:1.10.1790.10 173 286 1.3E-16 T 28-03-2018 IPR011608 PRD domain GO:0006355 CDW54_RS04495 57a86a7c22b80e412a5e886188000466 659 Pfam PF08279 HTH domain 6 63 9.0E-10 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CDW54_RS04495 57a86a7c22b80e412a5e886188000466 659 Gene3D G3DSA:3.40.930.10 510 655 9.2E-11 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CDW54_RS04495 57a86a7c22b80e412a5e886188000466 659 Gene3D G3DSA:1.10.10.10 1 68 2.6E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS04495 57a86a7c22b80e412a5e886188000466 659 Gene3D G3DSA:1.10.10.10 93 159 3.0E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS04495 57a86a7c22b80e412a5e886188000466 659 SUPERFAMILY SSF55804 515 651 1.67E-11 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CDW54_RS04495 57a86a7c22b80e412a5e886188000466 659 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 529 618 1.8E-7 T 28-03-2018 IPR002178 PTS EIIA type-2 domain CDW54_RS04495 57a86a7c22b80e412a5e886188000466 659 SUPERFAMILY SSF63520 202 286 6.28E-16 T 28-03-2018 IPR011608 PRD domain GO:0006355 CDW54_RS04495 57a86a7c22b80e412a5e886188000466 659 SUPERFAMILY SSF52794 404 485 2.62E-6 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CDW54_RS04495 57a86a7c22b80e412a5e886188000466 659 Pfam PF05043 Mga helix-turn-helix domain 96 172 2.5E-14 T 28-03-2018 IPR007737 Mga helix-turn-helix domain CDW54_RS04495 57a86a7c22b80e412a5e886188000466 659 Gene3D G3DSA:3.40.50.2300 401 492 1.6E-17 T 28-03-2018 CDW54_RS07435 6c9e4bcd05b9f3afc49a9e3fb3e9f6ce 711 SUPERFAMILY SSF52540 203 324 8.42E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS07435 6c9e4bcd05b9f3afc49a9e3fb3e9f6ce 711 SUPERFAMILY SSF52540 453 706 8.42E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS07435 6c9e4bcd05b9f3afc49a9e3fb3e9f6ce 711 Gene3D G3DSA:3.40.50.300 569 710 3.3E-14 T 28-03-2018 CDW54_RS07435 6c9e4bcd05b9f3afc49a9e3fb3e9f6ce 711 Pfam PF13245 AAA domain 214 544 1.3E-13 T 28-03-2018 CDW54_RS07435 6c9e4bcd05b9f3afc49a9e3fb3e9f6ce 711 Gene3D G3DSA:3.40.50.300 208 561 1.5E-31 T 28-03-2018 CDW54_RS05650 ebe1a7da8cbd7623a13fe873f3df8517 272 Pfam PF02096 60Kd inner membrane protein 57 239 2.7E-55 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CDW54_RS05650 ebe1a7da8cbd7623a13fe873f3df8517 272 Hamap MF_01811 Membrane protein insertase YidC [yidC]. 4 242 31.165 T 28-03-2018 IPR023060 Membrane insertase YidC/YidC1/YidC2, Firmicutes CDW54_RS05650 ebe1a7da8cbd7623a13fe873f3df8517 272 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 55 238 2.1E-62 T 28-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal CDW54_RS05650 ebe1a7da8cbd7623a13fe873f3df8517 272 PRINTS PR00701 60kDa inner membrane protein signature 121 144 1.2E-11 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CDW54_RS05650 ebe1a7da8cbd7623a13fe873f3df8517 272 PRINTS PR00701 60kDa inner membrane protein signature 205 228 1.2E-11 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CDW54_RS08080 bb5e1b30aab4a5a25f170b480454c614 208 SUPERFAMILY SSF52499 2 207 2.75E-35 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CDW54_RS08080 bb5e1b30aab4a5a25f170b480454c614 208 Pfam PF00857 Isochorismatase family 7 202 2.5E-27 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CDW54_RS08080 bb5e1b30aab4a5a25f170b480454c614 208 Gene3D G3DSA:3.40.50.850 1 208 4.4E-30 T 28-03-2018 CDW54_RS09640 411e382535d0b978c5d5761b279af9ec 174 Pfam PF00430 ATP synthase B/B' CF(0) 18 148 3.0E-42 T 28-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CDW54_RS09640 411e382535d0b978c5d5761b279af9ec 174 Gene3D G3DSA:1.20.5.620 45 133 4.7E-4 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CDW54_RS09640 411e382535d0b978c5d5761b279af9ec 174 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 23 165 8.8E-40 T 28-03-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 CDW54_RS09640 411e382535d0b978c5d5761b279af9ec 174 Hamap MF_01398 ATP synthase subunit b [atpF]. 8 149 12.941 T 28-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CDW54_RS09640 411e382535d0b978c5d5761b279af9ec 174 SUPERFAMILY SSF81573 73 132 1.22E-8 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CDW54_RS10960 863a41bd35e103b8c6ca8cfdedfdd134 341 SMART SM00507 254 312 1.3E-5 T 28-03-2018 IPR003615 HNH nuclease CDW54_RS10960 863a41bd35e103b8c6ca8cfdedfdd134 341 Gene3D G3DSA:3.40.1800.10 245 328 4.5E-13 T 28-03-2018 CDW54_RS10960 863a41bd35e103b8c6ca8cfdedfdd134 341 Pfam PF01844 HNH endonuclease 267 315 1.1E-11 T 28-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 CDW54_RS04575 64e70c7687f260b67e267c8e5f7f2617 318 SMART SM00729 28 257 1.1E-35 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CDW54_RS04575 64e70c7687f260b67e267c8e5f7f2617 318 SUPERFAMILY SSF102114 3 311 2.22E-49 T 28-03-2018 CDW54_RS04575 64e70c7687f260b67e267c8e5f7f2617 318 TIGRFAM TIGR01212 TIGR01212: radical SAM protein, TIGR01212 family 11 309 5.3E-110 T 28-03-2018 IPR005911 Protein YhcC-like GO:0051536 CDW54_RS04575 64e70c7687f260b67e267c8e5f7f2617 318 Gene3D G3DSA:3.80.30.20 37 268 1.0E-28 T 28-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe CDW54_RS04575 64e70c7687f260b67e267c8e5f7f2617 318 Pfam PF16199 Radical_SAM C-terminal domain 218 300 3.9E-22 T 28-03-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 CDW54_RS04575 64e70c7687f260b67e267c8e5f7f2617 318 Pfam PF04055 Radical SAM superfamily 48 209 3.3E-17 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CDW54_RS04570 8ee3f6c6c52487612895a2645345e567 218 SMART SM00014 86 199 7.2E-26 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CDW54_RS04570 8ee3f6c6c52487612895a2645345e567 218 SUPERFAMILY SSF48317 11 206 2.75E-39 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CDW54_RS04570 8ee3f6c6c52487612895a2645345e567 218 Gene3D G3DSA:1.20.144.10 42 216 1.9E-29 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CDW54_RS04570 8ee3f6c6c52487612895a2645345e567 218 Pfam PF01569 PAP2 superfamily 93 206 2.8E-19 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CDW54_RS02940 692334f4ff4910dcb25eced3644c4db2 225 Pfam PF06265 Protein of unknown function (DUF1027) 65 148 4.5E-37 T 28-03-2018 IPR009370 Protein of unknown function DUF1027 CDW54_RS02940 692334f4ff4910dcb25eced3644c4db2 225 PIRSF PIRSF012565 1 39 120.0 T 28-03-2018 IPR009370 Protein of unknown function DUF1027 CDW54_RS02940 692334f4ff4910dcb25eced3644c4db2 225 PIRSF PIRSF012565 33 225 7.6E-54 T 28-03-2018 IPR009370 Protein of unknown function DUF1027 CDW54_RS00725 9af011c70afc690e95fca4282b4524bb 144 SUPERFAMILY SSF51735 9 139 1.1E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS00725 9af011c70afc690e95fca4282b4524bb 144 Pfam PF13380 CoA binding domain 19 136 1.9E-36 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CDW54_RS00725 9af011c70afc690e95fca4282b4524bb 144 Gene3D G3DSA:3.40.50.720 15 140 2.1E-31 T 28-03-2018 CDW54_RS00725 9af011c70afc690e95fca4282b4524bb 144 SMART SM00881 15 109 3.3E-19 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CDW54_RS10220 a96911bc085dfe4ffd80e463a47530d4 113 Gene3D G3DSA:3.40.630.30 2 111 1.4E-5 T 28-03-2018 CDW54_RS10220 a96911bc085dfe4ffd80e463a47530d4 113 SUPERFAMILY SSF55729 1 62 6.07E-6 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDW54_RS01415 599b00d10924dafd67a9d0c1b74a8956 1104 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 276 698 4.7E-169 T 28-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDW54_RS01415 599b00d10924dafd67a9d0c1b74a8956 1104 Pfam PF14579 Helix-hairpin-helix motif 774 862 1.5E-20 T 28-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDW54_RS01415 599b00d10924dafd67a9d0c1b74a8956 1104 SMART SM00481 6 71 7.3E-13 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CDW54_RS01415 599b00d10924dafd67a9d0c1b74a8956 1104 Gene3D G3DSA:1.10.150.280 749 868 2.8E-6 T 28-03-2018 CDW54_RS01415 599b00d10924dafd67a9d0c1b74a8956 1104 Gene3D G3DSA:2.40.50.140 924 1020 5.9E-15 T 28-03-2018 CDW54_RS01415 599b00d10924dafd67a9d0c1b74a8956 1104 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 6 979 2.7E-287 T 28-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDW54_RS01415 599b00d10924dafd67a9d0c1b74a8956 1104 Pfam PF02811 PHP domain 10 105 1.0E-19 T 28-03-2018 IPR004013 PHP domain GO:0003824 CDW54_RS01415 599b00d10924dafd67a9d0c1b74a8956 1104 Gene3D G3DSA:3.20.20.140 1 247 1.1E-20 T 28-03-2018 CDW54_RS01415 599b00d10924dafd67a9d0c1b74a8956 1104 SUPERFAMILY SSF89550 10 89 3.34E-9 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CDW54_RS01415 599b00d10924dafd67a9d0c1b74a8956 1104 SUPERFAMILY SSF89550 159 238 3.34E-9 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CDW54_RS06870 c460c8e39a5a3dafb9f28334f0926042 247 Gene3D G3DSA:3.20.20.140 17 242 1.9E-17 T 28-03-2018 CDW54_RS06870 c460c8e39a5a3dafb9f28334f0926042 247 SUPERFAMILY SSF89550 19 244 1.14E-20 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CDW54_RS03085 4463c329469019f547e9188cf92d8632 349 Gene3D G3DSA:3.40.50.10490 1 201 7.3E-31 T 28-03-2018 CDW54_RS03085 4463c329469019f547e9188cf92d8632 349 Gene3D G3DSA:3.40.50.10490 202 336 1.3E-17 T 28-03-2018 CDW54_RS03085 4463c329469019f547e9188cf92d8632 349 SUPERFAMILY SSF53697 4 337 5.39E-57 T 28-03-2018 CDW54_RS03085 4463c329469019f547e9188cf92d8632 349 Pfam PF01380 SIS domain 35 154 1.6E-15 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CDW54_RS03000 6ea517c0414aeca580a6969820f13b2f 320 SUPERFAMILY SSF64182 14 305 6.28E-73 T 28-03-2018 CDW54_RS03000 6ea517c0414aeca580a6969820f13b2f 320 Pfam PF01368 DHH family 16 154 5.9E-13 T 28-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CDW54_RS03000 6ea517c0414aeca580a6969820f13b2f 320 Gene3D G3DSA:3.90.1640.10 2 179 6.6E-40 T 28-03-2018 CDW54_RS03000 6ea517c0414aeca580a6969820f13b2f 320 Pfam PF02272 DHHA1 domain 252 309 8.7E-7 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CDW54_RS03000 6ea517c0414aeca580a6969820f13b2f 320 Gene3D G3DSA:1.10.600.10 180 255 0.0011 T 28-03-2018 IPR008949 Isoprenoid synthase domain CDW54_RS07370 d101da709c6ab390b8f04720c8c8865d 225 SUPERFAMILY SSF52317 1 223 2.4E-68 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CDW54_RS07370 d101da709c6ab390b8f04720c8c8865d 225 Gene3D G3DSA:3.40.50.880 1 225 5.6E-50 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CDW54_RS07370 d101da709c6ab390b8f04720c8c8865d 225 Pfam PF01965 DJ-1/PfpI family 25 221 9.4E-10 T 28-03-2018 IPR002818 DJ-1/PfpI CDW54_RS02275 18350ec0f171fb1bbf2da4f972451c03 401 PIRSF PIRSF500216 5 400 5.8E-170 T 28-03-2018 IPR024024 D-alanyl transfer protein DltB CDW54_RS02275 18350ec0f171fb1bbf2da4f972451c03 401 PIRSF PIRSF016636 9 394 1.7E-82 T 28-03-2018 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB CDW54_RS02275 18350ec0f171fb1bbf2da4f972451c03 401 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 127 378 1.3E-16 T 28-03-2018 IPR004299 Membrane bound O-acyl transferase, MBOAT CDW54_RS02275 18350ec0f171fb1bbf2da4f972451c03 401 TIGRFAM TIGR04091 LTA_dltB: D-alanyl-lipoteichoic acid biosynthesis protein DltB 8 395 2.1E-163 T 28-03-2018 IPR024024 D-alanyl transfer protein DltB CDW54_RS04370 70c7668f789fcd6ab9e62ae29d98cfb0 278 Pfam PF01261 Xylose isomerase-like TIM barrel 30 236 5.3E-25 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CDW54_RS04370 70c7668f789fcd6ab9e62ae29d98cfb0 278 Gene3D G3DSA:3.20.20.150 2 272 4.1E-37 T 28-03-2018 CDW54_RS04370 70c7668f789fcd6ab9e62ae29d98cfb0 278 SUPERFAMILY SSF51658 2 258 8.9E-39 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CDW54_RS04845 ba11fa9b3607a93f558369d6d35a591e 168 Pfam PF04892 VanZ like family 15 161 1.2E-18 T 28-03-2018 IPR006976 VanZ-like CDW54_RS04845 ba11fa9b3607a93f558369d6d35a591e 168 PIRSF PIRSF019083 5 168 3.2E-57 T 28-03-2018 IPR016747 Phosphotransbutyrylase CDW54_RS03895 d6c35ea84c69ceca0e4719243553ee54 390 Gene3D G3DSA:3.40.1710.10 38 199 6.0E-12 T 28-03-2018 CDW54_RS03895 d6c35ea84c69ceca0e4719243553ee54 390 Pfam PF12698 ABC-2 family transporter protein 20 370 1.3E-15 T 28-03-2018 CDW54_RS07635 9838df0a60acc16ee63305972ada4940 194 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 9 193 35.451 T 28-03-2018 IPR004507 Flavin prenyltransferase UbiX/Pad1 CDW54_RS07635 9838df0a60acc16ee63305972ada4940 194 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 10 191 1.5E-68 T 28-03-2018 IPR004507 Flavin prenyltransferase UbiX/Pad1 CDW54_RS07635 9838df0a60acc16ee63305972ada4940 194 Gene3D G3DSA:3.40.50.1950 9 194 7.0E-55 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CDW54_RS07635 9838df0a60acc16ee63305972ada4940 194 Pfam PF02441 Flavoprotein 9 172 1.7E-24 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CDW54_RS07635 9838df0a60acc16ee63305972ada4940 194 SUPERFAMILY SSF52507 9 193 1.57E-60 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CDW54_RS00985 f72ae08e973bf5a64dd2c74e95817252 123 SUPERFAMILY SSF55729 41 104 2.13E-5 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDW54_RS00985 f72ae08e973bf5a64dd2c74e95817252 123 Gene3D G3DSA:3.40.630.30 8 122 1.3E-5 T 28-03-2018 CDW54_RS00185 7df5b600b2c9f0614eafbd30201c4a23 277 Pfam PF02673 Bacitracin resistance protein BacA 9 268 1.6E-87 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CDW54_RS00185 7df5b600b2c9f0614eafbd30201c4a23 277 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 9 266 3.1E-69 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CDW54_RS00185 7df5b600b2c9f0614eafbd30201c4a23 277 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 4 273 17.739 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CDW54_RS03050 862f3e814fad93bc8a5a3c4adcaa3dd7 579 Pfam PF03606 C4-dicarboxylate anaerobic carrier 20 574 8.0E-127 T 28-03-2018 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 CDW54_RS02470 1cacff5214bc5776d998a070de9de876 536 Gene3D G3DSA:3.40.50.300 1 286 9.0E-137 T 28-03-2018 CDW54_RS02470 1cacff5214bc5776d998a070de9de876 536 Pfam PF06418 CTP synthase N-terminus 3 267 4.4E-131 T 28-03-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CDW54_RS02470 1cacff5214bc5776d998a070de9de876 536 SUPERFAMILY SSF52540 1 270 4.69E-127 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS02470 1cacff5214bc5776d998a070de9de876 536 Pfam PF00117 Glutamine amidotransferase class-I 302 526 5.8E-58 T 28-03-2018 IPR017926 Glutamine amidotransferase CDW54_RS02470 1cacff5214bc5776d998a070de9de876 536 Gene3D G3DSA:3.40.50.880 287 536 4.9E-76 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CDW54_RS02470 1cacff5214bc5776d998a070de9de876 536 TIGRFAM TIGR00337 PyrG: CTP synthase 1 528 2.3E-257 T 28-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CDW54_RS02470 1cacff5214bc5776d998a070de9de876 536 SUPERFAMILY SSF52317 289 530 4.88E-79 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CDW54_RS02470 1cacff5214bc5776d998a070de9de876 536 Hamap MF_01227 CTP synthase [pyrG]. 2 533 52.118 T 28-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CDW54_RS05305 07e1e7de5fef03d49de4ff37b310e1aa 275 SUPERFAMILY SSF51658 1 260 1.93E-46 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CDW54_RS05305 07e1e7de5fef03d49de4ff37b310e1aa 275 Pfam PF01261 Xylose isomerase-like TIM barrel 20 213 5.1E-22 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CDW54_RS05305 07e1e7de5fef03d49de4ff37b310e1aa 275 Gene3D G3DSA:3.20.20.150 1 268 2.5E-40 T 28-03-2018 CDW54_RS06090 2333ecb6b17108a7747324ca20ef9c40 258 Gene3D G3DSA:3.60.15.10 1 258 9.2E-26 T 28-03-2018 IPR001279 Metallo-beta-lactamase CDW54_RS06090 2333ecb6b17108a7747324ca20ef9c40 258 SMART SM00849 6 201 0.0057 T 28-03-2018 IPR001279 Metallo-beta-lactamase CDW54_RS06090 2333ecb6b17108a7747324ca20ef9c40 258 SUPERFAMILY SSF56281 1 257 4.06E-20 T 28-03-2018 IPR001279 Metallo-beta-lactamase CDW54_RS06090 2333ecb6b17108a7747324ca20ef9c40 258 Pfam PF12706 Beta-lactamase superfamily domain 40 221 3.8E-11 T 28-03-2018 IPR001279 Metallo-beta-lactamase CDW54_RS05850 035da98224f2d23a70403deadc41c064 377 Gene3D G3DSA:1.10.3470.10 3 350 2.5E-35 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CDW54_RS05850 035da98224f2d23a70403deadc41c064 377 Pfam PF02653 Branched-chain amino acid transport system / permease component 54 335 5.8E-38 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CDW54_RS08600 3af9cf6d21cd790f5dd01e6e2b705738 78 SMART SM00530 2 57 7.5E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDW54_RS08600 3af9cf6d21cd790f5dd01e6e2b705738 78 SUPERFAMILY SSF47413 3 63 5.63E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDW54_RS08600 3af9cf6d21cd790f5dd01e6e2b705738 78 Gene3D G3DSA:1.10.260.40 1 78 5.9E-12 T 28-03-2018 CDW54_RS08600 3af9cf6d21cd790f5dd01e6e2b705738 78 Pfam PF01381 Helix-turn-helix 3 54 6.5E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDW54_RS09780 02248d861b9fdd5591abe08bf5d9bedd 306 Gene3D G3DSA:1.10.3720.10 12 297 2.8E-39 T 28-03-2018 CDW54_RS09780 02248d861b9fdd5591abe08bf5d9bedd 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 302 5.5E-29 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS09780 02248d861b9fdd5591abe08bf5d9bedd 306 SUPERFAMILY SSF161098 20 299 4.19E-36 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS09780 02248d861b9fdd5591abe08bf5d9bedd 306 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 21 302 2.5E-87 T 28-03-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 CDW54_RS12225 06b4d5bea0f15c4d58d4b7467917811d 671 SUPERFAMILY SSF52794 382 467 7.32E-9 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CDW54_RS12225 06b4d5bea0f15c4d58d4b7467917811d 671 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 526 668 1.3E-35 T 28-03-2018 IPR002178 PTS EIIA type-2 domain CDW54_RS12225 06b4d5bea0f15c4d58d4b7467917811d 671 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 573 589 - T 28-03-2018 IPR002178 PTS EIIA type-2 domain CDW54_RS12225 06b4d5bea0f15c4d58d4b7467917811d 671 SUPERFAMILY SSF63520 273 373 1.09E-19 T 28-03-2018 IPR011608 PRD domain GO:0006355 CDW54_RS12225 06b4d5bea0f15c4d58d4b7467917811d 671 Gene3D G3DSA:1.10.1790.10 274 374 2.2E-15 T 28-03-2018 IPR011608 PRD domain GO:0006355 CDW54_RS12225 06b4d5bea0f15c4d58d4b7467917811d 671 Gene3D G3DSA:1.10.10.10 70 135 1.6E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS12225 06b4d5bea0f15c4d58d4b7467917811d 671 SUPERFAMILY SSF55804 522 668 7.19E-39 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CDW54_RS12225 06b4d5bea0f15c4d58d4b7467917811d 671 Gene3D G3DSA:3.40.930.10 523 670 1.2E-35 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CDW54_RS12225 06b4d5bea0f15c4d58d4b7467917811d 671 Gene3D G3DSA:3.40.50.2300 380 471 4.1E-16 T 28-03-2018 CDW54_RS12225 06b4d5bea0f15c4d58d4b7467917811d 671 Pfam PF00874 PRD domain 281 369 8.4E-17 T 28-03-2018 IPR011608 PRD domain GO:0006355 CDW54_RS11100 12674df5e4263ed758ab18cc6e99fbfc 276 Gene3D G3DSA:1.10.3100.10 2 110 2.6E-12 T 28-03-2018 IPR027910 YdiL-like domain CDW54_RS11100 12674df5e4263ed758ab18cc6e99fbfc 276 SUPERFAMILY SSF47413 3 57 1.07E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDW54_RS11100 12674df5e4263ed758ab18cc6e99fbfc 276 Pfam PF01381 Helix-turn-helix 3 55 1.4E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDW54_RS11100 12674df5e4263ed758ab18cc6e99fbfc 276 SMART SM00530 1 55 9.8E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDW54_RS12305 fd9297a465c2f38b2725a07df4674547 293 Pfam PF02653 Branched-chain amino acid transport system / permease component 2 272 7.1E-29 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CDW54_RS12305 fd9297a465c2f38b2725a07df4674547 293 Gene3D G3DSA:1.10.3470.10 1 281 3.3E-34 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CDW54_RS05790 b267dcccf117eb9ee5108139c2c8df6c 341 Pfam PF13515 Fusaric acid resistance protein-like 197 319 1.9E-14 T 28-03-2018 CDW54_RS08850 d3e2c68981bd64c66a17d923e4014a5d 145 PRINTS PR01243 Nucleoside diphosphate kinase signature 112 131 6.8E-39 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CDW54_RS08850 d3e2c68981bd64c66a17d923e4014a5d 145 PRINTS PR01243 Nucleoside diphosphate kinase signature 4 26 6.8E-39 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CDW54_RS08850 d3e2c68981bd64c66a17d923e4014a5d 145 PRINTS PR01243 Nucleoside diphosphate kinase signature 68 85 6.8E-39 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CDW54_RS08850 d3e2c68981bd64c66a17d923e4014a5d 145 PRINTS PR01243 Nucleoside diphosphate kinase signature 89 105 6.8E-39 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CDW54_RS08850 d3e2c68981bd64c66a17d923e4014a5d 145 PRINTS PR01243 Nucleoside diphosphate kinase signature 48 67 6.8E-39 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CDW54_RS08850 d3e2c68981bd64c66a17d923e4014a5d 145 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 1 136 30.891 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CDW54_RS08850 d3e2c68981bd64c66a17d923e4014a5d 145 SUPERFAMILY SSF54919 1 137 9.04E-53 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CDW54_RS08850 d3e2c68981bd64c66a17d923e4014a5d 145 Gene3D G3DSA:3.30.70.141 1 145 1.5E-48 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CDW54_RS08850 d3e2c68981bd64c66a17d923e4014a5d 145 Pfam PF00334 Nucleoside diphosphate kinase 2 135 6.3E-51 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CDW54_RS08850 d3e2c68981bd64c66a17d923e4014a5d 145 SMART SM00562 1 138 7.6E-69 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CDW54_RS05770 50f39d85955255226b0f1e0d107c5373 272 Pfam PF02535 ZIP Zinc transporter 113 267 6.8E-20 T 28-03-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 CDW54_RS00840 65af988c9c75b4712510b0c2ecf1d55f 217 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 14 215 6.6E-58 T 28-03-2018 IPR005744 Hly-III GO:0016021|GO:0019835 CDW54_RS00840 65af988c9c75b4712510b0c2ecf1d55f 217 Pfam PF03006 Haemolysin-III related 11 210 1.1E-39 T 28-03-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 CDW54_RS02445 1d4071862fe6d47a54488cfa138b0fed 220 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 68 199 1.4E-36 T 28-03-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 CDW54_RS02445 1d4071862fe6d47a54488cfa138b0fed 220 Gene3D G3DSA:3.30.1380.10 41 211 2.1E-33 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CDW54_RS02445 1d4071862fe6d47a54488cfa138b0fed 220 SUPERFAMILY SSF55166 67 207 5.49E-31 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CDW54_RS08350 69007a76da3ab4c4be17aebaf572dc39 156 SUPERFAMILY SSF82649 3 142 7.85E-50 T 28-03-2018 CDW54_RS08350 69007a76da3ab4c4be17aebaf572dc39 156 Pfam PF01592 NifU-like N terminal domain 10 128 3.4E-27 T 28-03-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 CDW54_RS08350 69007a76da3ab4c4be17aebaf572dc39 156 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 6 140 3.1E-55 T 28-03-2018 CDW54_RS08350 69007a76da3ab4c4be17aebaf572dc39 156 Gene3D G3DSA:3.90.1010.10 3 141 2.8E-51 T 28-03-2018 CDW54_RS06640 889bdb902cbe23cd6c70db69376607d9 162 Gene3D G3DSA:3.20.20.80 43 155 1.6E-14 T 28-03-2018 CDW54_RS12660 d705c12599bdd286c1537db6dfcac59d 364 Gene3D G3DSA:3.20.20.70 3 238 9.6E-96 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDW54_RS12660 d705c12599bdd286c1537db6dfcac59d 364 Pfam PF05913 Bacterial protein of unknown function (DUF871) 3 359 5.7E-147 T 28-03-2018 IPR008589 Protein of unknown function DUF871, prokaryotic CDW54_RS12660 d705c12599bdd286c1537db6dfcac59d 364 SUPERFAMILY SSF51445 1 241 2.81E-95 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CDW54_RS12660 d705c12599bdd286c1537db6dfcac59d 364 SUPERFAMILY SSF50891 245 360 1.71E-42 T 28-03-2018 IPR029000 Cyclophilin-like domain CDW54_RS12660 d705c12599bdd286c1537db6dfcac59d 364 Gene3D G3DSA:2.40.100.10 246 360 4.7E-43 T 28-03-2018 IPR029000 Cyclophilin-like domain CDW54_RS09515 98bd8eba0421497a62dea7057236ce6c 276 Gene3D G3DSA:3.30.930.10 10 265 1.7E-32 T 28-03-2018 CDW54_RS09515 98bd8eba0421497a62dea7057236ce6c 276 SUPERFAMILY SSF55681 16 255 5.22E-60 T 28-03-2018 CDW54_RS09515 98bd8eba0421497a62dea7057236ce6c 276 Pfam PF03099 Biotin/lipoate A/B protein ligase family 61 172 4.7E-10 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CDW54_RS10215 5867ecc5c311967c115dfb149e28225e 224 Gene3D G3DSA:3.40.50.1110 2 209 4.1E-35 T 28-03-2018 CDW54_RS10215 5867ecc5c311967c115dfb149e28225e 224 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 7 197 5.8E-23 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CDW54_RS10215 5867ecc5c311967c115dfb149e28225e 224 ProSitePatterns PS01098 Lipolytic enzymes "G-D-S-L" family, serine active site. 5 16 - T 28-03-2018 IPR008265 Lipase, GDSL, active site GO:0006629|GO:0016298 Reactome: R-HSA-1482788|Reactome: R-HSA-975634 CDW54_RS10215 5867ecc5c311967c115dfb149e28225e 224 SUPERFAMILY SSF52266 2 206 4.5E-41 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CDW54_RS04450 fd59f331a62ad172e9f80148dc26f714 315 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 308 2.9E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS04450 fd59f331a62ad172e9f80148dc26f714 315 Gene3D G3DSA:1.10.3720.10 19 314 1.6E-43 T 28-03-2018 CDW54_RS04450 fd59f331a62ad172e9f80148dc26f714 315 SUPERFAMILY SSF161098 68 300 6.67E-49 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS07700 7dc02868088f1241942a1785f74f6e3b 120 SUPERFAMILY SSF159121 25 117 4.71E-28 T 28-03-2018 IPR006542 Protein of unknown function DUF1093 CDW54_RS07700 7dc02868088f1241942a1785f74f6e3b 120 Pfam PF06486 Protein of unknown function (DUF1093) 27 107 3.5E-27 T 28-03-2018 IPR006542 Protein of unknown function DUF1093 CDW54_RS07700 7dc02868088f1241942a1785f74f6e3b 120 TIGRFAM TIGR01655 yxeA_fam: conserved hypothetical protein 2 117 1.2E-24 T 28-03-2018 IPR006542 Protein of unknown function DUF1093 CDW54_RS02450 bf0e0b7716c39e7c1f7328262aafa2d0 371 SUPERFAMILY SSF47384 133 212 5.69E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDW54_RS02450 bf0e0b7716c39e7c1f7328262aafa2d0 371 Pfam PF00512 His Kinase A (phospho-acceptor) domain 148 210 3.9E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDW54_RS02450 bf0e0b7716c39e7c1f7328262aafa2d0 371 SMART SM00387 259 371 2.6E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS02450 bf0e0b7716c39e7c1f7328262aafa2d0 371 Gene3D G3DSA:3.30.565.10 221 371 4.9E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS02450 bf0e0b7716c39e7c1f7328262aafa2d0 371 Gene3D G3DSA:1.10.287.130 137 210 1.9E-14 T 28-03-2018 CDW54_RS02450 bf0e0b7716c39e7c1f7328262aafa2d0 371 PRINTS PR00344 Bacterial sensor protein C-terminal signature 356 369 6.4E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDW54_RS02450 bf0e0b7716c39e7c1f7328262aafa2d0 371 PRINTS PR00344 Bacterial sensor protein C-terminal signature 316 326 6.4E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDW54_RS02450 bf0e0b7716c39e7c1f7328262aafa2d0 371 PRINTS PR00344 Bacterial sensor protein C-terminal signature 333 351 6.4E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDW54_RS02450 bf0e0b7716c39e7c1f7328262aafa2d0 371 PRINTS PR00344 Bacterial sensor protein C-terminal signature 298 312 6.4E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDW54_RS02450 bf0e0b7716c39e7c1f7328262aafa2d0 371 SUPERFAMILY SSF55874 203 370 7.6E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS02450 bf0e0b7716c39e7c1f7328262aafa2d0 371 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 260 370 1.4E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS02450 bf0e0b7716c39e7c1f7328262aafa2d0 371 SMART SM00388 147 214 7.3E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDW54_RS02670 4e540a30145fdc959397c6041b96068f 319 SUPERFAMILY SSF53098 160 309 3.04E-21 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS02670 4e540a30145fdc959397c6041b96068f 319 Pfam PF00665 Integrase core domain 167 265 7.8E-10 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CDW54_RS02670 4e540a30145fdc959397c6041b96068f 319 Gene3D G3DSA:3.30.420.10 155 317 4.9E-22 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS02670 4e540a30145fdc959397c6041b96068f 319 Gene3D G3DSA:1.10.10.60 6 68 1.1E-4 T 28-03-2018 CDW54_RS00600 4439c855c864d9564bf0f4f2383ca104 207 Gene3D G3DSA:3.10.350.10 24 92 1.8E-15 T 28-03-2018 CDW54_RS00600 4439c855c864d9564bf0f4f2383ca104 207 Pfam PF01476 LysM domain 31 77 5.7E-12 T 28-03-2018 IPR018392 LysM domain CDW54_RS00600 4439c855c864d9564bf0f4f2383ca104 207 SMART SM00257 30 77 3.2E-9 T 28-03-2018 IPR018392 LysM domain CDW54_RS00600 4439c855c864d9564bf0f4f2383ca104 207 SUPERFAMILY SSF54106 30 77 2.75E-8 T 28-03-2018 IPR018392 LysM domain CDW54_RS02230 4e205c1cc624a7c155320a12121897a8 227 Pfam PF01596 O-methyltransferase 44 220 7.3E-29 T 28-03-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 CDW54_RS02230 4e205c1cc624a7c155320a12121897a8 227 SUPERFAMILY SSF53335 2 216 2.01E-44 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDW54_RS02230 4e205c1cc624a7c155320a12121897a8 227 Gene3D G3DSA:3.40.50.150 12 222 4.6E-39 T 28-03-2018 CDW54_RS04320 6253a7a7fc73cc9c92813876b1aebb29 230 Pfam PF04854 Protein of unknown function, DUF624 18 94 9.8E-25 T 28-03-2018 IPR006938 Protein of unknown function DUF624 CDW54_RS03940 a173f4c0b0c83488b247bc05ee6b8172 288 Gene3D G3DSA:3.40.50.150 17 282 2.9E-29 T 28-03-2018 CDW54_RS03940 a173f4c0b0c83488b247bc05ee6b8172 288 Pfam PF08241 Methyltransferase domain 97 183 8.2E-13 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CDW54_RS03940 a173f4c0b0c83488b247bc05ee6b8172 288 PIRSF PIRSF018249 4 283 4.5E-92 T 28-03-2018 IPR016718 rRNA (guanine-N1-)-methyltransferase A, predicted GO:0008168 CDW54_RS03940 a173f4c0b0c83488b247bc05ee6b8172 288 SUPERFAMILY SSF53335 20 271 1.14E-26 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDW54_RS00940 70fbc32ac043af1a0522f82ecae1ccbf 343 Pfam PF14493 Helix-turn-helix domain 243 329 2.8E-13 T 28-03-2018 IPR029491 Helicase Helix-turn-helix domain Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 CDW54_RS03440 130dcdd6c61de270a70a5940bd7b2ab2 146 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 47 63 - T 28-03-2018 IPR002178 PTS EIIA type-2 domain CDW54_RS03440 130dcdd6c61de270a70a5940bd7b2ab2 146 SUPERFAMILY SSF55804 3 142 1.96E-30 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CDW54_RS03440 130dcdd6c61de270a70a5940bd7b2ab2 146 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 6 143 1.4E-30 T 28-03-2018 IPR002178 PTS EIIA type-2 domain CDW54_RS03440 130dcdd6c61de270a70a5940bd7b2ab2 146 Gene3D G3DSA:3.40.930.10 3 145 5.8E-27 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CDW54_RS02300 b79ac0a6be72ddc2177de70d34e958a1 255 Pfam PF00005 ABC transporter 24 172 1.6E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS02300 b79ac0a6be72ddc2177de70d34e958a1 255 Gene3D G3DSA:3.40.50.300 1 244 4.9E-69 T 28-03-2018 CDW54_RS02300 b79ac0a6be72ddc2177de70d34e958a1 255 SUPERFAMILY SSF52540 4 225 8.18E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS02300 b79ac0a6be72ddc2177de70d34e958a1 255 SMART SM00382 33 241 3.2E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS09520 c2507d391971eb49f017c41166c6b33b 145 Gene3D G3DSA:2.40.128.20 1 145 1.3E-34 T 28-03-2018 IPR012674 Calycin CDW54_RS09520 c2507d391971eb49f017c41166c6b33b 145 SUPERFAMILY SSF50814 2 143 2.71E-31 T 28-03-2018 IPR012674 Calycin CDW54_RS09520 c2507d391971eb49f017c41166c6b33b 145 Pfam PF09148 Domain of unknown function (DUF1934) 11 141 2.5E-30 T 28-03-2018 IPR015231 Protein of unknown function DUF1934 CDW54_RS09865 7346b0627781b7b5f34e5db352251bb2 200 Gene3D G3DSA:1.20.120.20 120 199 0.0011 T 28-03-2018 CDW54_RS09865 7346b0627781b7b5f34e5db352251bb2 200 Gene3D G3DSA:1.20.120.20 26 119 2.5E-7 T 28-03-2018 CDW54_RS09865 7346b0627781b7b5f34e5db352251bb2 200 Pfam PF12732 YtxH-like protein 8 88 4.3E-12 T 28-03-2018 IPR024623 Uncharacterised protein family YtxH CDW54_RS08680 cbc57a8934dedf76d0123d02062fd1ae 278 SUPERFAMILY SSF53098 96 253 4.7E-32 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS08680 cbc57a8934dedf76d0123d02062fd1ae 278 Pfam PF13276 HTH-like domain 23 74 4.2E-11 T 28-03-2018 IPR025948 HTH-like domain CDW54_RS08680 cbc57a8934dedf76d0123d02062fd1ae 278 Gene3D G3DSA:3.30.420.10 97 268 1.9E-33 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS08680 cbc57a8934dedf76d0123d02062fd1ae 278 Gene3D G3DSA:1.10.10.10 14 88 6.0E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS08680 cbc57a8934dedf76d0123d02062fd1ae 278 Pfam PF00665 Integrase core domain 103 214 5.8E-22 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CDW54_RS06700 7cef5bd2c76f572aa7d601124b6be088 368 SUPERFAMILY SSF48208 25 364 9.98E-90 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CDW54_RS06700 7cef5bd2c76f572aa7d601124b6be088 368 Gene3D G3DSA:1.50.10.10 7 368 4.0E-78 T 28-03-2018 CDW54_RS06700 7cef5bd2c76f572aa7d601124b6be088 368 Pfam PF07470 Glycosyl Hydrolase Family 88 28 364 2.0E-96 T 28-03-2018 IPR010905 Glycosyl hydrolase, family 88 CDW54_RS03420 6f5505b50f2110eef25a0535e81df1a0 145 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 7 142 7.7E-31 T 28-03-2018 IPR002178 PTS EIIA type-2 domain CDW54_RS03420 6f5505b50f2110eef25a0535e81df1a0 145 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 47 63 - T 28-03-2018 IPR002178 PTS EIIA type-2 domain CDW54_RS03420 6f5505b50f2110eef25a0535e81df1a0 145 SUPERFAMILY SSF55804 3 142 1.31E-36 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CDW54_RS03420 6f5505b50f2110eef25a0535e81df1a0 145 Gene3D G3DSA:3.40.930.10 2 143 3.5E-30 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CDW54_RS06510 64fe45068a33c7f1b65909637670b7ed 107 Gene3D G3DSA:3.10.450.150 5 103 1.8E-30 T 28-03-2018 CDW54_RS06510 64fe45068a33c7f1b65909637670b7ed 107 Pfam PF06124 Staphylococcal protein of unknown function (DUF960) 10 103 1.9E-33 T 28-03-2018 IPR009303 Protein of unknown function DUF960 CDW54_RS11725 e95d067949d2adddebdce5ad8956faa4 121 Pfam PF03013 Pyrimidine dimer DNA glycosylase 1 109 2.2E-38 T 28-03-2018 IPR004260 Pyrimidine dimer DNA glycosylase CDW54_RS11725 e95d067949d2adddebdce5ad8956faa4 121 Gene3D G3DSA:1.10.440.10 2 97 3.4E-8 T 28-03-2018 IPR024796 T4 endonuclease V CDW54_RS11725 e95d067949d2adddebdce5ad8956faa4 121 TIGRFAM TIGR02328 TIGR02328: conserved hypothetical protein 1 120 5.1E-63 T 28-03-2018 IPR012650 Conserved hypothetical protein CHP02328 CDW54_RS04215 927ce79438e6dc846bb746096e64f3f9 114 Gene3D G3DSA:1.20.120.20 24 109 4.3E-4 T 28-03-2018 CDW54_RS04215 927ce79438e6dc846bb746096e64f3f9 114 Pfam PF12732 YtxH-like protein 6 86 2.1E-18 T 28-03-2018 IPR024623 Uncharacterised protein family YtxH CDW54_RS03425 096c99d5286f24bf833f582562604474 588 Pfam PF02378 Phosphotransferase system, EIIC 25 283 6.5E-17 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CDW54_RS03425 096c99d5286f24bf833f582562604474 588 Gene3D G3DSA:3.40.50.2300 374 475 4.8E-18 T 28-03-2018 CDW54_RS03425 096c99d5286f24bf833f582562604474 588 Gene3D G3DSA:3.40.50.2300 487 588 4.3E-6 T 28-03-2018 CDW54_RS03425 096c99d5286f24bf833f582562604474 588 TIGRFAM TIGR00851 mtlA: PTS system, mannitol-specific IIC component 15 351 9.2E-161 T 28-03-2018 IPR004718 Phosphotransferase system, mannitol-specific enzyme IIC GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.197|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 CDW54_RS03425 096c99d5286f24bf833f582562604474 588 SUPERFAMILY SSF52794 381 469 2.79E-22 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CDW54_RS03425 096c99d5286f24bf833f582562604474 588 SUPERFAMILY SSF52794 496 586 2.3E-10 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CDW54_RS03425 096c99d5286f24bf833f582562604474 588 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 383 468 2.9E-8 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CDW54_RS09880 97152283b3672ea176b20a5f26890c0f 781 SUPERFAMILY SSF53955 78 300 5.06E-56 T 28-03-2018 IPR023346 Lysozyme-like domain CDW54_RS09880 97152283b3672ea176b20a5f26890c0f 781 Pfam PF00912 Transglycosylase 88 273 7.0E-49 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CDW54_RS09880 97152283b3672ea176b20a5f26890c0f 781 Gene3D G3DSA:3.40.710.10 298 739 1.5E-71 T 28-03-2018 CDW54_RS09880 97152283b3672ea176b20a5f26890c0f 781 SUPERFAMILY SSF56601 258 277 3.15E-84 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CDW54_RS09880 97152283b3672ea176b20a5f26890c0f 781 SUPERFAMILY SSF56601 341 738 3.15E-84 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CDW54_RS09880 97152283b3672ea176b20a5f26890c0f 781 Gene3D G3DSA:1.10.3810.10 79 290 8.9E-59 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CDW54_RS09880 97152283b3672ea176b20a5f26890c0f 781 Pfam PF00905 Penicillin binding protein transpeptidase domain 394 637 2.4E-21 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CDW54_RS06230 e2a51b1d4cbe48221ba3c381d4180315 319 Gene3D G3DSA:1.10.3470.10 6 319 1.3E-38 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CDW54_RS06230 e2a51b1d4cbe48221ba3c381d4180315 319 Pfam PF01032 FecCD transport family 30 313 5.5E-49 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CDW54_RS06230 e2a51b1d4cbe48221ba3c381d4180315 319 SUPERFAMILY SSF81345 6 313 9.42E-52 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CDW54_RS01130 382110496c0f4241b5a16eed0df7ce96 108 SUPERFAMILY SSF46785 13 107 6.13E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS01130 382110496c0f4241b5a16eed0df7ce96 108 Pfam PF03551 Transcriptional regulator PadR-like family 15 89 2.8E-19 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CDW54_RS01130 382110496c0f4241b5a16eed0df7ce96 108 Gene3D G3DSA:1.10.10.10 4 108 1.5E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS01895 a71a4304db7acfe1fbbb0a91e04e1adc 266 Pfam PF13641 Glycosyltransferase like family 2 9 235 5.8E-7 T 28-03-2018 CDW54_RS01895 a71a4304db7acfe1fbbb0a91e04e1adc 266 Gene3D G3DSA:3.90.550.10 8 262 6.2E-26 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDW54_RS01895 a71a4304db7acfe1fbbb0a91e04e1adc 266 SUPERFAMILY SSF53448 172 256 3.09E-33 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDW54_RS01895 a71a4304db7acfe1fbbb0a91e04e1adc 266 SUPERFAMILY SSF53448 7 136 3.09E-33 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDW54_RS05180 f9b03e092a811975f1527771b2237fbb 319 Pfam PF00665 Integrase core domain 167 265 8.1E-10 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CDW54_RS05180 f9b03e092a811975f1527771b2237fbb 319 SUPERFAMILY SSF53098 160 309 4.17E-21 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS05180 f9b03e092a811975f1527771b2237fbb 319 Gene3D G3DSA:3.30.420.10 155 317 5.9E-22 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS05180 f9b03e092a811975f1527771b2237fbb 319 Gene3D G3DSA:1.10.10.60 6 68 1.1E-4 T 28-03-2018 CDW54_RS01110 f9b03e092a811975f1527771b2237fbb 319 Pfam PF00665 Integrase core domain 167 265 8.1E-10 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CDW54_RS01110 f9b03e092a811975f1527771b2237fbb 319 SUPERFAMILY SSF53098 160 309 4.17E-21 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS01110 f9b03e092a811975f1527771b2237fbb 319 Gene3D G3DSA:3.30.420.10 155 317 5.9E-22 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS01110 f9b03e092a811975f1527771b2237fbb 319 Gene3D G3DSA:1.10.10.60 6 68 1.1E-4 T 28-03-2018 CDW54_RS11950 2b9919a17146510f0b127288c5bbc53f 517 Pfam PF05043 Mga helix-turn-helix domain 96 170 8.2E-10 T 28-03-2018 IPR007737 Mga helix-turn-helix domain CDW54_RS11950 2b9919a17146510f0b127288c5bbc53f 517 Gene3D G3DSA:1.10.10.10 103 162 0.0044 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS11950 2b9919a17146510f0b127288c5bbc53f 517 Gene3D G3DSA:1.10.10.10 12 75 0.001 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS10560 c768f70442823b3479c28eee661275f8 706 PIRSF PIRSF005091 3 643 1.9E-191 T 28-03-2018 IPR012160 Lipoteichoic acid synthase-like CDW54_RS10560 c768f70442823b3479c28eee661275f8 706 Gene3D G3DSA:3.40.720.10 247 564 1.2E-35 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CDW54_RS10560 c768f70442823b3479c28eee661275f8 706 SUPERFAMILY SSF53649 251 656 2.24E-74 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CDW54_RS10560 c768f70442823b3479c28eee661275f8 706 Pfam PF00884 Sulfatase 252 554 8.3E-34 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CDW54_RS01935 ba13b209fe417fd62ea78e650b07b1d0 66 SUPERFAMILY SSF56349 29 66 3.53E-13 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CDW54_RS01935 ba13b209fe417fd62ea78e650b07b1d0 66 Gene3D G3DSA:1.10.443.10 18 66 2.3E-10 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CDW54_RS01935 ba13b209fe417fd62ea78e650b07b1d0 66 Pfam PF00589 Phage integrase family 29 66 1.6E-8 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CDW54_RS01440 8d17de3c0c50c880ac1f11920ef0438f 717 Pfam PF03717 Penicillin-binding Protein dimerisation domain 83 318 9.4E-38 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CDW54_RS01440 8d17de3c0c50c880ac1f11920ef0438f 717 SUPERFAMILY SSF56519 79 140 8.11E-31 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CDW54_RS01440 8d17de3c0c50c880ac1f11920ef0438f 717 SUPERFAMILY SSF56519 200 332 8.11E-31 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CDW54_RS01440 8d17de3c0c50c880ac1f11920ef0438f 717 Gene3D G3DSA:3.90.1310.10 51 333 1.6E-34 T 28-03-2018 CDW54_RS01440 8d17de3c0c50c880ac1f11920ef0438f 717 Gene3D G3DSA:3.40.710.10 334 715 5.6E-68 T 28-03-2018 CDW54_RS01440 8d17de3c0c50c880ac1f11920ef0438f 717 SUPERFAMILY SSF56601 335 713 2.21E-60 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CDW54_RS01440 8d17de3c0c50c880ac1f11920ef0438f 717 Pfam PF00905 Penicillin binding protein transpeptidase domain 366 708 4.1E-64 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CDW54_RS08970 83e614482a50e3e26272da2779cfbb85 106 Pfam PF00893 Small Multidrug Resistance protein 1 93 2.3E-29 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 CDW54_RS08970 83e614482a50e3e26272da2779cfbb85 106 SUPERFAMILY SSF103481 6 104 4.97E-19 T 28-03-2018 CDW54_RS05985 75b65cd31e8dbd648df70f11da2e7693 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 25.633 T 28-03-2018 IPR023053 Ribosomal protein S14, type Z CDW54_RS05985 75b65cd31e8dbd648df70f11da2e7693 61 Gene3D G3DSA:4.10.830.10 1 61 2.9E-21 T 28-03-2018 CDW54_RS05985 75b65cd31e8dbd648df70f11da2e7693 61 Pfam PF00253 Ribosomal protein S14p/S29e 12 60 1.5E-24 T 28-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDW54_RS05985 75b65cd31e8dbd648df70f11da2e7693 61 SUPERFAMILY SSF57716 4 61 2.28E-21 T 28-03-2018 CDW54_RS05985 75b65cd31e8dbd648df70f11da2e7693 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 28-03-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDW54_RS07360 e4a57cf1a2bf8779a7e49f1c259bf40f 144 SMART SM00347 30 130 8.0E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDW54_RS07360 e4a57cf1a2bf8779a7e49f1c259bf40f 144 Gene3D G3DSA:1.10.10.10 1 144 9.6E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS07360 e4a57cf1a2bf8779a7e49f1c259bf40f 144 Pfam PF13412 Winged helix-turn-helix DNA-binding 44 84 7.4E-8 T 28-03-2018 CDW54_RS07360 e4a57cf1a2bf8779a7e49f1c259bf40f 144 SUPERFAMILY SSF46785 4 141 3.97E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS03870 6f6fdbf44b1dde62e6e9298bae5ef543 56 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 2 56 1.7E-20 T 28-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 CDW54_RS03870 6f6fdbf44b1dde62e6e9298bae5ef543 56 Hamap MF_00422 Protein translocase subunit SecE [secE]. 1 53 11.622 T 28-03-2018 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CDW54_RS03870 6f6fdbf44b1dde62e6e9298bae5ef543 56 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 2 54 1.8E-19 T 28-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CDW54_RS03870 6f6fdbf44b1dde62e6e9298bae5ef543 56 Gene3D G3DSA:1.20.5.1030 1 55 1.7E-19 T 28-03-2018 CDW54_RS07815 c3fe40bad106bcb1bc47195915b036ae 239 PIRSF PIRSF000705 2 218 2.0E-52 T 28-03-2018 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 CDW54_RS07815 c3fe40bad106bcb1bc47195915b036ae 239 Pfam PF01712 Deoxynucleoside kinase 6 208 1.1E-56 T 28-03-2018 IPR031314 Deoxynucleoside kinase domain CDW54_RS07815 c3fe40bad106bcb1bc47195915b036ae 239 SUPERFAMILY SSF52540 1 208 1.12E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS07815 c3fe40bad106bcb1bc47195915b036ae 239 Gene3D G3DSA:3.40.50.300 2 236 1.6E-39 T 28-03-2018 CDW54_RS02030 58d0c6d268a14742339860d3461b5126 95 Pfam PF02325 YGGT family 15 79 1.9E-14 T 28-03-2018 IPR003425 CCB3/YggT GO:0016020 CDW54_RS06820 17533749c0566311978b38266525d610 359 Gene3D G3DSA:2.40.30.40 71 163 6.4E-22 T 28-03-2018 IPR023367 Peptidase M42, domain 2 CDW54_RS06820 17533749c0566311978b38266525d610 359 Gene3D G3DSA:3.40.630.10 168 357 7.2E-37 T 28-03-2018 CDW54_RS06820 17533749c0566311978b38266525d610 359 TIGRFAM TIGR03107 glu_aminopep: glutamyl aminopeptidase 6 355 1.9E-182 T 28-03-2018 IPR017538 Peptidase M42, glutamyl aminopeptidase MetaCyc: PWY-5706|MetaCyc: PWY-5707|MetaCyc: PWY-7614 CDW54_RS06820 17533749c0566311978b38266525d610 359 PIRSF PIRSF001123 2 358 1.3E-134 T 28-03-2018 IPR008007 Peptidase M42 CDW54_RS06820 17533749c0566311978b38266525d610 359 SUPERFAMILY SSF101821 72 182 2.9E-24 T 28-03-2018 CDW54_RS06820 17533749c0566311978b38266525d610 359 Pfam PF05343 M42 glutamyl aminopeptidase 46 338 2.7E-97 T 28-03-2018 IPR008007 Peptidase M42 CDW54_RS06820 17533749c0566311978b38266525d610 359 SUPERFAMILY SSF53187 174 355 1.6E-64 T 28-03-2018 CDW54_RS06820 17533749c0566311978b38266525d610 359 SUPERFAMILY SSF53187 5 82 1.6E-64 T 28-03-2018 CDW54_RS06925 6c5293e3ba3ec0c03d2276f85da29d4d 351 Pfam PF13303 Phosphotransferase system, EIIC 15 344 1.0E-86 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CDW54_RS01175 5a611db1e69e53436055d237ddbc8e7f 317 SUPERFAMILY SSF53098 160 309 5.5E-17 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS01175 5a611db1e69e53436055d237ddbc8e7f 317 Gene3D G3DSA:1.10.10.60 3 48 1.4E-4 T 28-03-2018 CDW54_RS01175 5a611db1e69e53436055d237ddbc8e7f 317 Gene3D G3DSA:3.30.420.10 156 314 9.3E-18 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS01660 5a611db1e69e53436055d237ddbc8e7f 317 SUPERFAMILY SSF53098 160 309 5.5E-17 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS01660 5a611db1e69e53436055d237ddbc8e7f 317 Gene3D G3DSA:1.10.10.60 3 48 1.4E-4 T 28-03-2018 CDW54_RS01660 5a611db1e69e53436055d237ddbc8e7f 317 Gene3D G3DSA:3.30.420.10 156 314 9.3E-18 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS03280 bca2d2a841f42695f8ef5c7c07e611a7 213 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 8 105 1.3E-28 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CDW54_RS03280 bca2d2a841f42695f8ef5c7c07e611a7 213 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 30 209 8.1E-26 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS03280 bca2d2a841f42695f8ef5c7c07e611a7 213 Gene3D G3DSA:1.10.3720.10 5 211 2.4E-42 T 28-03-2018 CDW54_RS03280 bca2d2a841f42695f8ef5c7c07e611a7 213 SUPERFAMILY SSF161098 9 194 1.05E-41 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS03430 2f82eeb04f0244e1921c2b28d54178b8 225 SUPERFAMILY SSF52540 3 213 2.71E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS03430 2f82eeb04f0244e1921c2b28d54178b8 225 SMART SM00382 27 209 2.7E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS03430 2f82eeb04f0244e1921c2b28d54178b8 225 Gene3D G3DSA:3.40.50.300 1 225 3.9E-38 T 28-03-2018 CDW54_RS03430 2f82eeb04f0244e1921c2b28d54178b8 225 Pfam PF00005 ABC transporter 19 156 9.4E-18 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS10660 80a7d92d8555091815de6178321a58ba 631 PIRSF PIRSF001589 1 629 2.3E-165 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CDW54_RS10660 80a7d92d8555091815de6178321a58ba 631 Gene3D G3DSA:3.40.50.620 219 619 3.0E-59 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDW54_RS10660 80a7d92d8555091815de6178321a58ba 631 Gene3D G3DSA:3.60.20.10 1 218 3.1E-59 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CDW54_RS10660 80a7d92d8555091815de6178321a58ba 631 Pfam PF00733 Asparagine synthase 237 611 1.2E-77 T 28-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 CDW54_RS10660 80a7d92d8555091815de6178321a58ba 631 Pfam PF13537 Glutamine amidotransferase domain 46 163 1.5E-46 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain CDW54_RS10660 80a7d92d8555091815de6178321a58ba 631 SUPERFAMILY SSF52402 465 610 1.05E-62 T 28-03-2018 CDW54_RS10660 80a7d92d8555091815de6178321a58ba 631 SUPERFAMILY SSF52402 216 371 1.05E-62 T 28-03-2018 CDW54_RS10660 80a7d92d8555091815de6178321a58ba 631 SUPERFAMILY SSF56235 1 221 2.66E-67 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CDW54_RS10660 80a7d92d8555091815de6178321a58ba 631 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 548 3.1E-159 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CDW54_RS06050 1ba5a0e53cb73a9fec8db0a522f32f24 312 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 311 37.104 T 28-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDW54_RS06050 1ba5a0e53cb73a9fec8db0a522f32f24 312 SUPERFAMILY SSF55257 4 48 1.57E-32 T 28-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDW54_RS06050 1ba5a0e53cb73a9fec8db0a522f32f24 312 SUPERFAMILY SSF55257 170 224 1.57E-32 T 28-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDW54_RS06050 1ba5a0e53cb73a9fec8db0a522f32f24 312 Gene3D G3DSA:3.30.1360.10 1 84 2.5E-21 T 28-03-2018 CDW54_RS06050 1ba5a0e53cb73a9fec8db0a522f32f24 312 Gene3D G3DSA:3.30.1360.10 121 222 1.5E-26 T 28-03-2018 CDW54_RS06050 1ba5a0e53cb73a9fec8db0a522f32f24 312 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 238 302 4.5E-28 T 28-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDW54_RS06050 1ba5a0e53cb73a9fec8db0a522f32f24 312 Gene3D G3DSA:1.10.150.20 239 312 1.1E-24 T 28-03-2018 CDW54_RS06050 1ba5a0e53cb73a9fec8db0a522f32f24 312 SUPERFAMILY SSF47789 245 310 2.49E-23 T 28-03-2018 CDW54_RS06050 1ba5a0e53cb73a9fec8db0a522f32f24 312 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 57 149 2.2E-23 T 28-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDW54_RS06050 1ba5a0e53cb73a9fec8db0a522f32f24 312 SMART SM00662 18 225 5.2E-97 T 28-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDW54_RS06050 1ba5a0e53cb73a9fec8db0a522f32f24 312 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 24 219 1.5E-24 T 28-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDW54_RS06050 1ba5a0e53cb73a9fec8db0a522f32f24 312 SUPERFAMILY SSF56553 48 169 4.19E-44 T 28-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDW54_RS06050 1ba5a0e53cb73a9fec8db0a522f32f24 312 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 251 312 2.0E-28 T 28-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDW54_RS06050 1ba5a0e53cb73a9fec8db0a522f32f24 312 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 18 310 2.2E-124 T 28-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDW54_RS12535 bfe692c97092f17709f9260334703178 215 Hamap MF_00130 Holliday junction resolvase RecU [recU]. 1 215 98.311 T 28-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 CDW54_RS12535 bfe692c97092f17709f9260334703178 215 SUPERFAMILY SSF52980 36 201 2.95E-67 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CDW54_RS12535 bfe692c97092f17709f9260334703178 215 PIRSF PIRSF037785 25 208 5.7E-76 T 28-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 CDW54_RS12535 bfe692c97092f17709f9260334703178 215 Pfam PF03838 Recombination protein U 34 199 1.7E-64 T 28-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 CDW54_RS12535 bfe692c97092f17709f9260334703178 215 TIGRFAM TIGR00648 recU: recombination protein U 33 199 1.1E-65 T 28-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 CDW54_RS12535 bfe692c97092f17709f9260334703178 215 Gene3D G3DSA:3.40.1350.10 35 201 2.2E-62 T 28-03-2018 CDW54_RS11555 d171e57a09aba7ee9545e44893bd716f 357 Gene3D G3DSA:3.30.420.10 113 350 2.3E-5 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS11555 d171e57a09aba7ee9545e44893bd716f 357 Pfam PF00872 Transposase, Mutator family 28 336 4.8E-94 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CDW54_RS00585 782b8c6abeb39df8917913cc15c91334 80 SUPERFAMILY SSF54593 9 67 2.13E-10 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDW54_RS00585 782b8c6abeb39df8917913cc15c91334 80 Gene3D G3DSA:3.10.180.10 2 80 9.4E-11 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDW54_RS04350 a1f32684ad9689d738c925da06d41b41 473 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 17 167 1.8E-16 T 28-03-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 CDW54_RS04350 a1f32684ad9689d738c925da06d41b41 473 Gene3D G3DSA:3.40.50.720 1 264 1.4E-73 T 28-03-2018 CDW54_RS04350 a1f32684ad9689d738c925da06d41b41 473 Gene3D G3DSA:1.10.1040.10 267 470 4.2E-52 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CDW54_RS04350 a1f32684ad9689d738c925da06d41b41 473 PRINTS PR00084 Mannitol dehydrogenase signature 18 28 3.5E-8 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CDW54_RS04350 a1f32684ad9689d738c925da06d41b41 473 PRINTS PR00084 Mannitol dehydrogenase signature 200 213 3.5E-8 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CDW54_RS04350 a1f32684ad9689d738c925da06d41b41 473 PRINTS PR00084 Mannitol dehydrogenase signature 230 245 3.5E-8 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CDW54_RS04350 a1f32684ad9689d738c925da06d41b41 473 PRINTS PR00084 Mannitol dehydrogenase signature 159 172 3.5E-8 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CDW54_RS04350 a1f32684ad9689d738c925da06d41b41 473 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 200 442 3.7E-46 T 28-03-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 CDW54_RS04350 a1f32684ad9689d738c925da06d41b41 473 SUPERFAMILY SSF51735 5 263 1.42E-73 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS04350 a1f32684ad9689d738c925da06d41b41 473 SUPERFAMILY SSF48179 268 466 1.19E-44 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CDW54_RS03795 73e98a9a5712d7cc43a7f1cc9d300d03 379 Pfam PF01594 AI-2E family transporter 24 352 2.4E-78 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like CDW54_RS07710 884f26651af9c36b3eba6fc4dd7a1dc8 600 PIRSF PIRSF018968 1 410 1.2E-44 T 28-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 CDW54_RS07710 884f26651af9c36b3eba6fc4dd7a1dc8 600 PIRSF PIRSF018968 372 599 1.1E-20 T 28-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 CDW54_RS07710 884f26651af9c36b3eba6fc4dd7a1dc8 600 Pfam PF02687 FtsX-like permease family 85 178 1.7E-8 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CDW54_RS08005 437165db4cafbd6d8537b6f49f04b094 248 SMART SM00382 30 215 4.6E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS08005 437165db4cafbd6d8537b6f49f04b094 248 SUPERFAMILY SSF52540 4 230 1.11E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS08005 437165db4cafbd6d8537b6f49f04b094 248 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS08005 437165db4cafbd6d8537b6f49f04b094 248 Pfam PF00005 ABC transporter 21 166 6.3E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS08005 437165db4cafbd6d8537b6f49f04b094 248 Gene3D G3DSA:3.40.50.300 5 238 2.6E-58 T 28-03-2018 CDW54_RS06590 6cf25cd9d2c9408b7f368343ca845d7c 120 Gene3D G3DSA:2.30.30.110 1 115 6.5E-35 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CDW54_RS06590 6cf25cd9d2c9408b7f368343ca845d7c 120 SUPERFAMILY SSF50118 1 112 1.8E-38 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CDW54_RS06590 6cf25cd9d2c9408b7f368343ca845d7c 120 PIRSF PIRSF033490 1 112 1.0E-35 T 28-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 CDW54_RS06590 6cf25cd9d2c9408b7f368343ca845d7c 120 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 3 109 9.2E-32 T 28-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 CDW54_RS03505 bd4a66ef2cbbdebd924a1ed00178f8bb 117 SUPERFAMILY SSF141530 2 116 3.01E-32 T 28-03-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 CDW54_RS03505 bd4a66ef2cbbdebd924a1ed00178f8bb 117 ProDom PD015842 PTS IIA COMPONENT GLUCITOL/SORBITOL-SPECIFIC SYSTEM ENZYME TRANSFERASE SYSTEM PHOSPHOTRANSFERASE EIIA 1 114 2.0E-60 T 28-03-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 CDW54_RS03505 bd4a66ef2cbbdebd924a1ed00178f8bb 117 Gene3D G3DSA:2.40.33.40 1 116 1.1E-34 T 28-03-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 CDW54_RS03505 bd4a66ef2cbbdebd924a1ed00178f8bb 117 Pfam PF03829 PTS system glucitol/sorbitol-specific IIA component 2 114 1.9E-31 T 28-03-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 CDW54_RS01140 a3b59f098dd1dc424e23da1287ce60ef 465 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 362 370 - T 28-03-2018 IPR018120 Glycoside hydrolase family 1, active site CDW54_RS01140 a3b59f098dd1dc424e23da1287ce60ef 465 Pfam PF00232 Glycosyl hydrolase family 1 4 463 3.1E-134 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS01140 a3b59f098dd1dc424e23da1287ce60ef 465 Gene3D G3DSA:3.20.20.80 4 463 3.4E-150 T 28-03-2018 CDW54_RS01140 a3b59f098dd1dc424e23da1287ce60ef 465 SUPERFAMILY SSF51445 2 457 2.72E-164 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CDW54_RS01140 a3b59f098dd1dc424e23da1287ce60ef 465 PRINTS PR00131 Glycosyl hydrolase family 1 signature 290 304 2.3E-15 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS01140 a3b59f098dd1dc424e23da1287ce60ef 465 PRINTS PR00131 Glycosyl hydrolase family 1 signature 431 443 2.3E-15 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS01140 a3b59f098dd1dc424e23da1287ce60ef 465 PRINTS PR00131 Glycosyl hydrolase family 1 signature 386 397 2.3E-15 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS01140 a3b59f098dd1dc424e23da1287ce60ef 465 PRINTS PR00131 Glycosyl hydrolase family 1 signature 362 370 2.3E-15 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS01140 a3b59f098dd1dc424e23da1287ce60ef 465 PRINTS PR00131 Glycosyl hydrolase family 1 signature 407 424 2.3E-15 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS04285 b5564a7820daa3205cd59ca6e409b6aa 522 Gene3D G3DSA:2.115.10.20 4 320 7.3E-76 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CDW54_RS04285 b5564a7820daa3205cd59ca6e409b6aa 522 SUPERFAMILY SSF49899 320 517 3.32E-48 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CDW54_RS04285 b5564a7820daa3205cd59ca6e409b6aa 522 Pfam PF04616 Glycosyl hydrolases family 43 7 295 7.5E-94 T 28-03-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 CDW54_RS04285 b5564a7820daa3205cd59ca6e409b6aa 522 Gene3D G3DSA:2.60.120.200 321 515 9.2E-31 T 28-03-2018 CDW54_RS04285 b5564a7820daa3205cd59ca6e409b6aa 522 SUPERFAMILY SSF75005 7 303 1.71E-90 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CDW54_RS12525 3d948a0f9b210f99fcb4f4717086f1ea 139 Hamap MF_02011 Cell cycle protein GpsB [gpsB]. 1 104 24.392 T 28-03-2018 IPR011229 Cell cycle protein GpsB CDW54_RS12525 3d948a0f9b210f99fcb4f4717086f1ea 139 Gene3D G3DSA:1.20.5.1000 26 135 0.001 T 28-03-2018 CDW54_RS12525 3d948a0f9b210f99fcb4f4717086f1ea 139 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 7 39 3.2E-16 T 28-03-2018 IPR019933 DivIVA domain CDW54_RS12525 3d948a0f9b210f99fcb4f4717086f1ea 139 Pfam PF05103 DivIVA protein 6 69 1.1E-17 T 28-03-2018 IPR007793 DivIVA family CDW54_RS00850 38950ef72bb93e6dbc6c38207fd119b2 315 ProSitePatterns PS00091 Thymidylate synthase active site. 177 205 - T 28-03-2018 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CDW54_RS00850 38950ef72bb93e6dbc6c38207fd119b2 315 Hamap MF_00008 Thymidylate synthase [thyA]. 2 315 39.678 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CDW54_RS00850 38950ef72bb93e6dbc6c38207fd119b2 315 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 3 315 9.9E-167 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CDW54_RS00850 38950ef72bb93e6dbc6c38207fd119b2 315 Gene3D G3DSA:3.30.572.10 1 315 4.1E-129 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CDW54_RS00850 38950ef72bb93e6dbc6c38207fd119b2 315 SUPERFAMILY SSF55831 2 315 1.06E-131 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CDW54_RS00850 38950ef72bb93e6dbc6c38207fd119b2 315 PRINTS PR00108 Thymidylate synthase family signature 166 185 3.9E-48 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CDW54_RS00850 38950ef72bb93e6dbc6c38207fd119b2 315 PRINTS PR00108 Thymidylate synthase family signature 192 207 3.9E-48 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CDW54_RS00850 38950ef72bb93e6dbc6c38207fd119b2 315 PRINTS PR00108 Thymidylate synthase family signature 43 64 3.9E-48 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CDW54_RS00850 38950ef72bb93e6dbc6c38207fd119b2 315 PRINTS PR00108 Thymidylate synthase family signature 210 236 3.9E-48 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CDW54_RS00850 38950ef72bb93e6dbc6c38207fd119b2 315 PRINTS PR00108 Thymidylate synthase family signature 248 265 3.9E-48 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CDW54_RS00850 38950ef72bb93e6dbc6c38207fd119b2 315 Pfam PF00303 Thymidylate synthase 3 315 1.9E-120 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CDW54_RS08575 93054e002b608791f7cdd5acafe0d4fe 468 Hamap MF_01574 6-phospho-beta-galactosidase [lacG]. 1 468 66.2 T 28-03-2018 IPR005928 6-phospho-beta-galactosidase GO:0019512|GO:0033920 KEGG: 00052+3.2.1.85 CDW54_RS08575 93054e002b608791f7cdd5acafe0d4fe 468 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 9 23 - T 28-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site CDW54_RS08575 93054e002b608791f7cdd5acafe0d4fe 468 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 371 379 - T 28-03-2018 IPR018120 Glycoside hydrolase family 1, active site CDW54_RS08575 93054e002b608791f7cdd5acafe0d4fe 468 TIGRFAM TIGR01233 lacG: 6-phospho-beta-galactosidase 3 468 5.4E-292 T 28-03-2018 IPR005928 6-phospho-beta-galactosidase GO:0019512|GO:0033920 KEGG: 00052+3.2.1.85 CDW54_RS08575 93054e002b608791f7cdd5acafe0d4fe 468 PRINTS PR00131 Glycosyl hydrolase family 1 signature 412 429 2.8E-24 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS08575 93054e002b608791f7cdd5acafe0d4fe 468 PRINTS PR00131 Glycosyl hydrolase family 1 signature 436 448 2.8E-24 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS08575 93054e002b608791f7cdd5acafe0d4fe 468 PRINTS PR00131 Glycosyl hydrolase family 1 signature 391 402 2.8E-24 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS08575 93054e002b608791f7cdd5acafe0d4fe 468 PRINTS PR00131 Glycosyl hydrolase family 1 signature 290 304 2.8E-24 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS08575 93054e002b608791f7cdd5acafe0d4fe 468 PRINTS PR00131 Glycosyl hydrolase family 1 signature 371 379 2.8E-24 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS08575 93054e002b608791f7cdd5acafe0d4fe 468 Pfam PF00232 Glycosyl hydrolase family 1 3 465 2.2E-166 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS08575 93054e002b608791f7cdd5acafe0d4fe 468 Gene3D G3DSA:3.20.20.80 1 468 1.1E-146 T 28-03-2018 CDW54_RS08575 93054e002b608791f7cdd5acafe0d4fe 468 SUPERFAMILY SSF51445 2 465 1.85E-161 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CDW54_RS02785 578884111c0eca2b32d923684b079db9 454 PIRSF PIRSF006351 4 449 2.0E-124 T 28-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 CDW54_RS02785 578884111c0eca2b32d923684b079db9 454 Pfam PF02378 Phosphotransferase system, EIIC 32 365 1.3E-48 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CDW54_RS02785 578884111c0eca2b32d923684b079db9 454 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 15 439 1.1E-102 T 28-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 CDW54_RS03345 1d14d70e4403782ae314d97addd71574 341 PIRSF PIRSF004930 1 341 2.4E-123 T 28-03-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 CDW54_RS03345 1d14d70e4403782ae314d97addd71574 341 SUPERFAMILY SSF55821 7 207 1.68E-62 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CDW54_RS03345 1d14d70e4403782ae314d97addd71574 341 Pfam PF03481 Putative GTP-binding controlling metal-binding 197 335 1.8E-25 T 28-03-2018 IPR005145 Putative GTP-binding controlling metal-binding domain CDW54_RS03345 1d14d70e4403782ae314d97addd71574 341 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 3 206 6.4E-62 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 CDW54_RS03345 1d14d70e4403782ae314d97addd71574 341 Gene3D G3DSA:3.90.870.10 1 210 7.2E-74 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CDW54_RS03345 1d14d70e4403782ae314d97addd71574 341 Pfam PF01300 Telomere recombination 16 195 2.1E-54 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 CDW54_RS04940 a9630313961d5666d6d1590f4bfa6e85 296 Pfam PF03755 YicC-like family, N-terminal region 1 161 6.1E-37 T 28-03-2018 IPR013527 YicC-like, N-terminal CDW54_RS04940 a9630313961d5666d6d1590f4bfa6e85 296 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 296 2.7E-65 T 28-03-2018 IPR005229 Conserved hypothetical protein CHP00255 CDW54_RS04940 a9630313961d5666d6d1590f4bfa6e85 296 Pfam PF08340 Domain of unknown function (DUF1732) 213 296 2.5E-33 T 28-03-2018 IPR013551 Domain of unknown function DUF1732 CDW54_RS11365 e0ef20e6b7cae13f47e1d4f1e3f5a1a0 128 SUPERFAMILY SSF54611 1 122 4.9E-40 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CDW54_RS11365 e0ef20e6b7cae13f47e1d4f1e3f5a1a0 128 Pfam PF06619 Protein of unknown function (DUF1149) 1 122 3.4E-47 T 28-03-2018 IPR009530 Protein of unknown function DUF1149 CDW54_RS11365 e0ef20e6b7cae13f47e1d4f1e3f5a1a0 128 Gene3D G3DSA:3.10.420.10 1 122 1.3E-38 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CDW54_RS11365 e0ef20e6b7cae13f47e1d4f1e3f5a1a0 128 PIRSF PIRSF031568 1 124 5.5E-44 T 28-03-2018 IPR009530 Protein of unknown function DUF1149 CDW54_RS06120 2af7cf8e45fea524cded5b1f81aa711c 206 Gene3D G3DSA:3.40.50.300 9 126 3.7E-4 T 28-03-2018 CDW54_RS06120 2af7cf8e45fea524cded5b1f81aa711c 206 Pfam PF13401 AAA domain 61 107 8.0E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS06120 2af7cf8e45fea524cded5b1f81aa711c 206 SUPERFAMILY SSF52540 64 200 1.17E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS01775 7a8cd1476fff4a208e0d3f65ca7b28b1 386 SUPERFAMILY SSF56601 62 379 1.49E-59 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CDW54_RS01775 7a8cd1476fff4a208e0d3f65ca7b28b1 386 Pfam PF00144 Beta-lactamase 80 358 5.0E-34 T 28-03-2018 IPR001466 Beta-lactamase-related CDW54_RS01775 7a8cd1476fff4a208e0d3f65ca7b28b1 386 Gene3D G3DSA:3.40.710.10 57 385 2.3E-49 T 28-03-2018 CDW54_RS08940 89f674359eacdf464187899294f30695 298 Pfam PF13580 SIS domain 39 162 2.7E-7 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CDW54_RS08940 89f674359eacdf464187899294f30695 298 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 188 205 - T 28-03-2018 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 CDW54_RS08940 89f674359eacdf464187899294f30695 298 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 5 298 42.423 T 28-03-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 CDW54_RS08940 89f674359eacdf464187899294f30695 298 TIGRFAM TIGR00274 TIGR00274: N-acetylmuramic acid 6-phosphate etherase 9 296 2.8E-118 T 28-03-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 CDW54_RS08940 89f674359eacdf464187899294f30695 298 Gene3D G3DSA:1.10.8.10 272 298 2.0E-5 T 28-03-2018 CDW54_RS08940 89f674359eacdf464187899294f30695 298 Gene3D G3DSA:1.10.8.10 246 271 2.1E-10 T 28-03-2018 CDW54_RS08940 89f674359eacdf464187899294f30695 298 Gene3D G3DSA:3.40.50.10490 13 245 6.4E-52 T 28-03-2018 CDW54_RS08940 89f674359eacdf464187899294f30695 298 SUPERFAMILY SSF53697 8 251 2.89E-71 T 28-03-2018 CDW54_RS11595 c76f7e8374998a27a70b6360c87e002f 263 Pfam PF05857 TraX protein 11 257 8.8E-31 T 28-03-2018 IPR008875 TraX CDW54_RS10250 8d83499d54672e594a8f84d4f7cbdf9f 179 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 3 16 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CDW54_RS10250 8d83499d54672e594a8f84d4f7cbdf9f 179 Gene3D G3DSA:3.40.50.300 1 175 2.7E-15 T 28-03-2018 CDW54_RS10250 8d83499d54672e594a8f84d4f7cbdf9f 179 SUPERFAMILY SSF52540 1 121 3.51E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS01970 9230552cab156012a8fc8c6d47775ff4 106 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 9 101 1.4E-33 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CDW54_RS01970 9230552cab156012a8fc8c6d47775ff4 106 PIRSF PIRSF000699 1 106 1.9E-34 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CDW54_RS01970 9230552cab156012a8fc8c6d47775ff4 106 SUPERFAMILY SSF46973 4 102 5.89E-34 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CDW54_RS01970 9230552cab156012a8fc8c6d47775ff4 106 Gene3D G3DSA:1.20.58.80 4 102 1.6E-34 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CDW54_RS11640 728e74fc10945dd80a80170af19a90ad 163 Pfam PF06923 Glucitol operon activator protein (GutM) 7 114 1.7E-36 T 28-03-2018 IPR009693 Glucitol operon activator CDW54_RS11640 728e74fc10945dd80a80170af19a90ad 163 PIRSF PIRSF011474 2 160 6.1E-54 T 28-03-2018 IPR009693 Glucitol operon activator CDW54_RS03615 54b92ef4369fadd442ebe0e8b8275974 120 Gene3D G3DSA:3.40.1720.10 11 103 1.1E-20 T 28-03-2018 CDW54_RS03615 54b92ef4369fadd442ebe0e8b8275974 120 Pfam PF08860 Domain of unknown function (DUF1827) 13 86 4.7E-8 T 28-03-2018 IPR014959 Protein of unknown function DUF1827 CDW54_RS03985 b33424a9467dfe5033873f7a49053340 332 Pfam PF06054 Competence protein CoiA-like family 18 283 1.4E-38 T 28-03-2018 IPR010330 Competence-induced protein CoiA-like CDW54_RS03985 b33424a9467dfe5033873f7a49053340 332 PIRSF PIRSF007487 1 327 1.2E-58 T 28-03-2018 IPR021176 Competence-induced protein CoiA CDW54_RS04945 5d9c1c75042ac47e4cf2480b45832b34 72 Pfam PF02229 Transcriptional Coactivator p15 (PC4) 20 68 3.2E-11 T 28-03-2018 IPR003173 Transcriptional coactivator p15 (PC4) GO:0003677|GO:0003713|GO:0006355 CDW54_RS04945 5d9c1c75042ac47e4cf2480b45832b34 72 PIRSF PIRSF037246 1 72 4.4E-39 T 28-03-2018 IPR017154 Uncharacterised conserved protein UCP037246 CDW54_RS04065 370ffae68642b9fa497644181ac0241f 419 Pfam PF00067 Cytochrome P450 279 399 3.5E-14 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CDW54_RS04065 370ffae68642b9fa497644181ac0241f 419 SUPERFAMILY SSF48264 16 410 5.5E-51 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CDW54_RS04065 370ffae68642b9fa497644181ac0241f 419 Gene3D G3DSA:1.10.630.10 9 416 4.7E-41 T 28-03-2018 CDW54_RS11790 fdbbd5a5065aee12f983d0ca057c3a00 62 Pfam PF10031 Small integral membrane protein (DUF2273) 6 50 3.1E-13 T 28-03-2018 IPR018730 Protein of unknown function DUF2273 CDW54_RS08165 678f4d619dd4ebe258948e3959524383 220 Pfam PF10112 5-bromo-4-chloroindolyl phosphate hydrolysis protein 10 204 1.0E-53 T 28-03-2018 IPR018770 5-bromo-4-chloroindolyl phosphate hydrolysis protein CDW54_RS08205 0dd4c92e0d3bdcfd4ce5fa4a9abcdf91 291 Gene3D G3DSA:3.90.70.10 130 290 2.1E-10 T 28-03-2018 CDW54_RS08205 0dd4c92e0d3bdcfd4ce5fa4a9abcdf91 291 SUPERFAMILY SSF54001 218 275 8.6E-5 T 28-03-2018 CDW54_RS12250 5c7dcbf355307693a4d2dca6616b030f 404 SUPERFAMILY SSF103473 7 395 3.27E-49 T 28-03-2018 IPR020846 Major facilitator superfamily domain CDW54_RS12250 5c7dcbf355307693a4d2dca6616b030f 404 Pfam PF07690 Major Facilitator Superfamily 13 234 2.3E-26 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDW54_RS12250 5c7dcbf355307693a4d2dca6616b030f 404 Gene3D G3DSA:1.20.1250.20 1 189 1.3E-24 T 28-03-2018 CDW54_RS12250 5c7dcbf355307693a4d2dca6616b030f 404 Gene3D G3DSA:1.20.1250.20 190 404 1.4E-17 T 28-03-2018 CDW54_RS12065 3974de565a2db9ff8f0384544bfc1447 502 Pfam PF08903 Domain of unknown function (DUF1846) 4 500 5.0E-235 T 28-03-2018 IPR014999 Uncharacterised protein family UPF0371 CDW54_RS12065 3974de565a2db9ff8f0384544bfc1447 502 Gene3D G3DSA:3.10.630.10 231 277 1.3E-14 T 28-03-2018 CDW54_RS12065 3974de565a2db9ff8f0384544bfc1447 502 Gene3D G3DSA:3.10.630.10 3 230 1.4E-106 T 28-03-2018 CDW54_RS12065 3974de565a2db9ff8f0384544bfc1447 502 Gene3D G3DSA:1.20.1570.10 278 338 2.6E-30 T 28-03-2018 CDW54_RS12065 3974de565a2db9ff8f0384544bfc1447 502 PIRSF PIRSF033132 2 502 3.8E-246 T 28-03-2018 IPR014999 Uncharacterised protein family UPF0371 CDW54_RS00220 cf1d8a8957334c6743e61ae3638861a9 179 SUPERFAMILY SSF53927 28 161 9.37E-38 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CDW54_RS00220 cf1d8a8957334c6743e61ae3638861a9 179 Gene3D G3DSA:3.40.140.10 24 170 4.8E-36 T 28-03-2018 CDW54_RS00220 cf1d8a8957334c6743e61ae3638861a9 179 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 91 126 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CDW54_RS00220 cf1d8a8957334c6743e61ae3638861a9 179 TIGRFAM TIGR02571 ComEB: ComE operon protein 2 23 170 4.9E-79 T 28-03-2018 IPR013404 Competence operon E, ComEB CDW54_RS00220 cf1d8a8957334c6743e61ae3638861a9 179 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 27 136 3.2E-25 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CDW54_RS00220 cf1d8a8957334c6743e61ae3638861a9 179 PIRSF PIRSF006019 17 172 2.0E-55 T 28-03-2018 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CDW54_RS12430 b803045f8be277eee691707cba1ff2a1 143 ProDom PD091538 PORE-FORMING FORMING PORE PEPTIDE EBSA PEPTIDE GBS1458 SMU.692 SAG1388 2 129 3.0E-7 T 28-03-2018 IPR020215 Pore-forming protein, EbsA CDW54_RS12430 b803045f8be277eee691707cba1ff2a1 143 Pfam PF17255 Family of unknown function (DUF5322) 2 131 1.9E-48 T 28-03-2018 IPR020215 Pore-forming protein, EbsA CDW54_RS08315 ac62c1f4497d35cb4be13e9c6a6356d8 112 SUPERFAMILY SSF51230 8 112 7.3E-26 T 28-03-2018 IPR011053 Single hybrid motif CDW54_RS08315 ac62c1f4497d35cb4be13e9c6a6356d8 112 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 45 74 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CDW54_RS08315 ac62c1f4497d35cb4be13e9c6a6356d8 112 Pfam PF01597 Glycine cleavage H-protein 9 112 9.1E-23 T 28-03-2018 IPR033753 Glycine cleavage system H-protein/Simiate CDW54_RS08315 ac62c1f4497d35cb4be13e9c6a6356d8 112 Gene3D G3DSA:2.40.50.100 6 112 5.8E-26 T 28-03-2018 CDW54_RS02250 105acd2adc6dc8d2cf3500c65c788b3f 246 Pfam PF00753 Metallo-beta-lactamase superfamily 20 211 6.8E-22 T 28-03-2018 IPR001279 Metallo-beta-lactamase CDW54_RS02250 105acd2adc6dc8d2cf3500c65c788b3f 246 Gene3D G3DSA:3.60.15.10 1 242 3.6E-41 T 28-03-2018 IPR001279 Metallo-beta-lactamase CDW54_RS02250 105acd2adc6dc8d2cf3500c65c788b3f 246 SUPERFAMILY SSF56281 1 232 1.14E-47 T 28-03-2018 IPR001279 Metallo-beta-lactamase CDW54_RS02250 105acd2adc6dc8d2cf3500c65c788b3f 246 SMART SM00849 18 211 9.8E-12 T 28-03-2018 IPR001279 Metallo-beta-lactamase CDW54_RS00615 613102ce98fbf318695aecd8aafff3c6 330 SUPERFAMILY SSF53850 36 319 2.57E-38 T 28-03-2018 CDW54_RS00615 613102ce98fbf318695aecd8aafff3c6 330 Gene3D G3DSA:3.40.190.10 32 149 4.5E-16 T 28-03-2018 CDW54_RS00615 613102ce98fbf318695aecd8aafff3c6 330 Gene3D G3DSA:3.40.190.10 150 330 5.9E-22 T 28-03-2018 CDW54_RS00615 613102ce98fbf318695aecd8aafff3c6 330 Pfam PF09084 NMT1/THI5 like 44 258 1.7E-70 T 28-03-2018 IPR015168 SsuA/THI5-like CDW54_RS05100 8a61e25c7e3e1447f304d568caf583f0 385 Gene3D G3DSA:3.40.50.1010 166 302 2.1E-27 T 28-03-2018 IPR029060 PIN domain-like CDW54_RS05100 8a61e25c7e3e1447f304d568caf583f0 385 SMART SM00670 171 278 5.5E-11 T 28-03-2018 IPR002716 PIN domain CDW54_RS05100 8a61e25c7e3e1447f304d568caf583f0 385 SUPERFAMILY SSF88723 171 299 8.69E-26 T 28-03-2018 IPR029060 PIN domain-like CDW54_RS08650 b833b02c6e10bf022ed48079b6149f4d 140 Gene3D G3DSA:2.60.120.10 16 140 2.0E-21 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CDW54_RS08650 b833b02c6e10bf022ed48079b6149f4d 140 SUPERFAMILY SSF51182 4 123 1.53E-23 T 28-03-2018 IPR011051 RmlC-like cupin domain CDW54_RS08650 b833b02c6e10bf022ed48079b6149f4d 140 Pfam PF07883 Cupin domain 41 116 3.4E-16 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CDW54_RS12335 7d245808eff23aacb624c8057e1063fc 234 Gene3D G3DSA:3.10.200.10 5 228 4.8E-40 T 28-03-2018 IPR001148 Alpha carbonic anhydrase CDW54_RS12335 7d245808eff23aacb624c8057e1063fc 234 Pfam PF00194 Eukaryotic-type carbonic anhydrase 8 228 1.3E-23 T 28-03-2018 IPR001148 Alpha carbonic anhydrase CDW54_RS12335 7d245808eff23aacb624c8057e1063fc 234 SUPERFAMILY SSF51069 7 228 4.84E-53 T 28-03-2018 IPR001148 Alpha carbonic anhydrase CDW54_RS12335 7d245808eff23aacb624c8057e1063fc 234 SMART SM01057 9 229 1.0E-25 T 28-03-2018 IPR001148 Alpha carbonic anhydrase CDW54_RS03880 688c45b97db2af489c1d92950b479454 214 SMART SM00116 12 61 0.007 T 28-03-2018 IPR000644 CBS domain CDW54_RS03880 688c45b97db2af489c1d92950b479454 214 SUPERFAMILY SSF54631 4 124 2.4E-21 T 28-03-2018 CDW54_RS03880 688c45b97db2af489c1d92950b479454 214 Gene3D G3DSA:3.10.580.10 111 196 0.022 T 28-03-2018 CDW54_RS03880 688c45b97db2af489c1d92950b479454 214 Pfam PF00571 CBS domain 11 58 7.5E-6 T 28-03-2018 IPR000644 CBS domain CDW54_RS03880 688c45b97db2af489c1d92950b479454 214 PIRSF PIRSF035040 1 212 1.6E-95 T 28-03-2018 IPR017036 Uncharacterised conserved protein UCP035040, CBS-type CDW54_RS03880 688c45b97db2af489c1d92950b479454 214 Gene3D G3DSA:3.10.580.10 3 110 7.7E-14 T 28-03-2018 CDW54_RS01430 6ea4ae0c93e4bbd2ebf6c6d5cb719239 478 PIRSF PIRSF005353 1 477 1.2E-165 T 28-03-2018 IPR026033 Purine permease PbuG-like CDW54_RS01430 6ea4ae0c93e4bbd2ebf6c6d5cb719239 478 Pfam PF00860 Permease family 17 437 1.4E-42 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CDW54_RS03310 017294d799d3210a3e25aa56a624ac48 210 SUPERFAMILY SSF141571 46 202 2.75E-39 T 28-03-2018 CDW54_RS03310 017294d799d3210a3e25aa56a624ac48 210 Pfam PF13599 Pentapeptide repeats (9 copies) 66 142 1.8E-14 T 28-03-2018 IPR001646 Pentapeptide repeat CDW54_RS03310 017294d799d3210a3e25aa56a624ac48 210 Gene3D G3DSA:2.160.10.20 114 205 1.7E-14 T 28-03-2018 CDW54_RS03310 017294d799d3210a3e25aa56a624ac48 210 Gene3D G3DSA:2.160.10.20 42 113 7.2E-13 T 28-03-2018 CDW54_RS09985 21970d7381d9342dbcf6a1857971415f 459 Pfam PF05525 Branched-chain amino acid transport protein 10 437 1.3E-123 T 28-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CDW54_RS09985 21970d7381d9342dbcf6a1857971415f 459 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 17 429 2.5E-105 T 28-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CDW54_RS06325 f1b7f322607dfeb909c827078bedcab5 179 PIRSF PIRSF016661 1 178 3.6E-42 T 28-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 CDW54_RS06325 f1b7f322607dfeb909c827078bedcab5 179 Pfam PF02632 BioY family 28 168 2.4E-37 T 28-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 CDW54_RS05385 858e59247c1d89a10a4849b6e82541f5 174 Pfam PF04978 Protein of unknown function (DUF664) 7 169 1.9E-9 T 28-03-2018 IPR007061 Protein of unknown function DUF664 CDW54_RS05385 858e59247c1d89a10a4849b6e82541f5 174 SUPERFAMILY SSF109854 2 171 1.33E-19 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CDW54_RS05385 858e59247c1d89a10a4849b6e82541f5 174 Gene3D G3DSA:1.20.120.450 1 173 1.5E-23 T 28-03-2018 CDW54_RS09545 a2c6ab35600f2b92b324fda3a457c8d7 294 SUPERFAMILY SSF88713 91 278 2.47E-58 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CDW54_RS09545 a2c6ab35600f2b92b324fda3a457c8d7 294 Gene3D G3DSA:3.20.20.370 38 284 5.9E-56 T 28-03-2018 CDW54_RS09545 a2c6ab35600f2b92b324fda3a457c8d7 294 Pfam PF01522 Polysaccharide deacetylase 93 205 7.0E-33 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CDW54_RS04535 465f68d933da865917e5b042c88a8186 253 Gene3D G3DSA:1.10.1660.10 2 127 3.6E-22 T 28-03-2018 CDW54_RS04535 465f68d933da865917e5b042c88a8186 253 SMART SM00422 5 74 6.3E-13 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CDW54_RS04535 465f68d933da865917e5b042c88a8186 253 SUPERFAMILY SSF46955 3 115 1.14E-23 T 28-03-2018 IPR009061 Putative DNA-binding domain CDW54_RS04535 465f68d933da865917e5b042c88a8186 253 Pfam PF00376 MerR family regulatory protein 6 43 1.2E-12 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CDW54_RS07755 bcc4503954872ee3a36ec8bfee02b4df 199 SUPERFAMILY SSF52499 5 196 4.84E-43 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CDW54_RS07755 bcc4503954872ee3a36ec8bfee02b4df 199 Gene3D G3DSA:3.40.50.850 2 199 2.1E-36 T 28-03-2018 CDW54_RS07755 bcc4503954872ee3a36ec8bfee02b4df 199 Pfam PF00857 Isochorismatase family 15 190 7.0E-37 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CDW54_RS09690 b73344883b88a48c5ee92051ba87355b 155 Pfam PF00583 Acetyltransferase (GNAT) family 31 114 2.5E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CDW54_RS09690 b73344883b88a48c5ee92051ba87355b 155 Gene3D G3DSA:3.40.630.30 1 153 4.4E-25 T 28-03-2018 CDW54_RS09690 b73344883b88a48c5ee92051ba87355b 155 SUPERFAMILY SSF55729 12 149 4.46E-24 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDW54_RS09860 f0f9b0d42b3062a227b0c99c9f9d930f 146 Gene3D G3DSA:1.10.287.500 23 128 7.4E-5 T 28-03-2018 CDW54_RS09860 f0f9b0d42b3062a227b0c99c9f9d930f 146 Pfam PF06103 Bacterial protein of unknown function (DUF948) 6 100 3.1E-26 T 28-03-2018 IPR009293 Uncharacterised protein family UPF0478 CDW54_RS09860 f0f9b0d42b3062a227b0c99c9f9d930f 146 SUPERFAMILY SSF58104 25 115 2.49E-5 T 28-03-2018 CDW54_RS12700 3d3087d056b4793d835237ef0a199e14 172 Gene3D G3DSA:3.60.21.10 1 170 3.4E-27 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CDW54_RS12700 3d3087d056b4793d835237ef0a199e14 172 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 143 9.1E-28 T 28-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 CDW54_RS12700 3d3087d056b4793d835237ef0a199e14 172 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 149 3.4E-25 T 28-03-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 CDW54_RS12700 3d3087d056b4793d835237ef0a199e14 172 SUPERFAMILY SSF56300 1 166 2.73E-44 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CDW54_RS05820 f23d5b5fba68aa5f6533884ba5fbe715 338 SMART SM00354 2 73 3.2E-27 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS05820 f23d5b5fba68aa5f6533884ba5fbe715 338 SUPERFAMILY SSF47413 2 61 7.62E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDW54_RS05820 f23d5b5fba68aa5f6533884ba5fbe715 338 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 50 1.6E-18 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS05820 f23d5b5fba68aa5f6533884ba5fbe715 338 Gene3D G3DSA:3.40.50.2300 63 173 3.5E-22 T 28-03-2018 CDW54_RS05820 f23d5b5fba68aa5f6533884ba5fbe715 338 Gene3D G3DSA:1.10.260.40 3 62 1.3E-17 T 28-03-2018 CDW54_RS05820 f23d5b5fba68aa5f6533884ba5fbe715 338 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 28-03-2018 CDW54_RS05820 f23d5b5fba68aa5f6533884ba5fbe715 338 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 1.3E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS05820 f23d5b5fba68aa5f6533884ba5fbe715 338 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 1.3E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDW54_RS05820 f23d5b5fba68aa5f6533884ba5fbe715 338 Gene3D G3DSA:3.40.50.2300 174 335 1.3E-46 T 28-03-2018 CDW54_RS05820 f23d5b5fba68aa5f6533884ba5fbe715 338 SUPERFAMILY SSF53822 62 333 2.75E-79 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CDW54_RS05820 f23d5b5fba68aa5f6533884ba5fbe715 338 Pfam PF13377 Periplasmic binding protein-like domain 174 332 4.4E-35 T 28-03-2018 CDW54_RS09945 88278e44a4ed8b3c7b89f36822b5d929 477 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 368 376 - T 28-03-2018 IPR018120 Glycoside hydrolase family 1, active site CDW54_RS09945 88278e44a4ed8b3c7b89f36822b5d929 477 Gene3D G3DSA:3.20.20.80 1 477 3.2E-149 T 28-03-2018 CDW54_RS09945 88278e44a4ed8b3c7b89f36822b5d929 477 Pfam PF00232 Glycosyl hydrolase family 1 3 471 6.8E-133 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS09945 88278e44a4ed8b3c7b89f36822b5d929 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 411 428 3.7E-17 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS09945 88278e44a4ed8b3c7b89f36822b5d929 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 368 376 3.7E-17 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS09945 88278e44a4ed8b3c7b89f36822b5d929 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 436 448 3.7E-17 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS09945 88278e44a4ed8b3c7b89f36822b5d929 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 302 316 3.7E-17 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS09945 88278e44a4ed8b3c7b89f36822b5d929 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 389 400 3.7E-17 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS09945 88278e44a4ed8b3c7b89f36822b5d929 477 SUPERFAMILY SSF51445 2 472 3.11E-159 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CDW54_RS09945 88278e44a4ed8b3c7b89f36822b5d929 477 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 7 21 - T 28-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site CDW54_RS06425 e63002c4d7db939980874bfbd4ab2100 196 Pfam PF06736 Protein of unknown function (DUF1211) 5 89 3.4E-27 T 28-03-2018 IPR010617 Endosomal/lysomomal potassium channel TMEM175 GO:0005267 CDW54_RS04815 98358987408c100eccaec2ebd57e5292 531 Pfam PF01943 Polysaccharide biosynthesis protein 10 307 1.5E-34 T 28-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CDW54_RS04815 98358987408c100eccaec2ebd57e5292 531 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 359 507 1.1E-16 T 28-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CDW54_RS00455 6629e3b6bbf48dc69f717526e5fea5c1 193 TIGRFAM TIGR01744 XPRTase: xanthine phosphoribosyltransferase 3 190 6.5E-84 T 28-03-2018 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 CDW54_RS00455 6629e3b6bbf48dc69f717526e5fea5c1 193 Gene3D G3DSA:3.40.50.2020 3 188 1.4E-25 T 28-03-2018 CDW54_RS00455 6629e3b6bbf48dc69f717526e5fea5c1 193 Hamap MF_01184 Xanthine phosphoribosyltransferase [xpt]. 1 189 41.444 T 28-03-2018 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 CDW54_RS00455 6629e3b6bbf48dc69f717526e5fea5c1 193 Pfam PF00156 Phosphoribosyl transferase domain 44 156 1.4E-9 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CDW54_RS00455 6629e3b6bbf48dc69f717526e5fea5c1 193 SUPERFAMILY SSF53271 2 189 1.61E-48 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CDW54_RS09815 08b40f0459fa676e294278410076624e 255 Pfam PF07907 YibE/F-like protein 4 242 5.8E-54 T 28-03-2018 IPR012507 YibE/F-like CDW54_RS09815 08b40f0459fa676e294278410076624e 255 PIRSF PIRSF031503 1 255 7.3E-49 T 28-03-2018 IPR014564 Uncharacterised conserved protein UCP031503, transmembrane CDW54_RS08985 fff84ee19386ff5afbb1e1cce747d505 314 Pfam PF06166 Protein of unknown function (DUF979) 17 313 6.3E-109 T 28-03-2018 IPR009323 Protein of unknown function DUF979 CDW54_RS07195 856103718e049019a3f728775809e0e2 120 SUPERFAMILY SSF142906 1 119 1.31E-27 T 28-03-2018 CDW54_RS07195 856103718e049019a3f728775809e0e2 120 Pfam PF04237 YjbR 20 117 1.8E-14 T 28-03-2018 IPR007351 Uncharacterised protein YjbR CDW54_RS06430 244f4fa2f539688de03cb1cb8888ff3a 449 Pfam PF00324 Amino acid permease 15 448 7.3E-108 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CDW54_RS06430 244f4fa2f539688de03cb1cb8888ff3a 449 PIRSF PIRSF006060 1 449 3.0E-63 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CDW54_RS06830 afd683c3fbb0faf30f096899d42cccff 154 PIRSF PIRSF006276 1 149 9.2E-22 T 28-03-2018 IPR006015 Universal stress protein A CDW54_RS06830 afd683c3fbb0faf30f096899d42cccff 154 Gene3D G3DSA:3.40.50.620 1 152 5.8E-31 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDW54_RS06830 afd683c3fbb0faf30f096899d42cccff 154 SUPERFAMILY SSF52402 5 148 3.1E-31 T 28-03-2018 CDW54_RS06830 afd683c3fbb0faf30f096899d42cccff 154 Pfam PF00582 Universal stress protein family 5 145 2.6E-28 T 28-03-2018 IPR006016 UspA GO:0006950 CDW54_RS06830 afd683c3fbb0faf30f096899d42cccff 154 PRINTS PR01438 Universal stress protein signature 106 118 8.2E-17 T 28-03-2018 IPR006015 Universal stress protein A CDW54_RS06830 afd683c3fbb0faf30f096899d42cccff 154 PRINTS PR01438 Universal stress protein signature 124 146 8.2E-17 T 28-03-2018 IPR006015 Universal stress protein A CDW54_RS06830 afd683c3fbb0faf30f096899d42cccff 154 PRINTS PR01438 Universal stress protein signature 5 23 8.2E-17 T 28-03-2018 IPR006015 Universal stress protein A CDW54_RS11585 3dcbe0ddea821b7ceb6231303c47c7fb 261 Gene3D G3DSA:3.40.50.720 2 259 9.1E-13 T 28-03-2018 CDW54_RS11585 3dcbe0ddea821b7ceb6231303c47c7fb 261 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 166 7.1E-8 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CDW54_RS11585 3dcbe0ddea821b7ceb6231303c47c7fb 261 SUPERFAMILY SSF51735 3 256 1.11E-19 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS05705 6ecf3856825bd830d90349b111765d4f 170 Pfam PF00436 Single-strand binding protein family 2 103 1.7E-37 T 28-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 CDW54_RS05705 6ecf3856825bd830d90349b111765d4f 170 PIRSF PIRSF002070 2 154 9.6E-40 T 28-03-2018 CDW54_RS05705 6ecf3856825bd830d90349b111765d4f 170 SUPERFAMILY SSF50249 2 170 1.44E-54 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDW54_RS05705 6ecf3856825bd830d90349b111765d4f 170 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 2 170 1.3E-46 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CDW54_RS05705 6ecf3856825bd830d90349b111765d4f 170 Gene3D G3DSA:2.40.50.140 1 122 6.8E-42 T 28-03-2018 CDW54_RS05705 6ecf3856825bd830d90349b111765d4f 170 Hamap MF_00984 Single-stranded DNA-binding protein. 2 107 36.168 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CDW54_RS03370 2be0a114fa92b54c67729fd7765ffb53 173 Pfam PF13673 Acetyltransferase (GNAT) domain 49 150 6.3E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CDW54_RS03370 2be0a114fa92b54c67729fd7765ffb53 173 Gene3D G3DSA:3.40.630.30 28 171 2.2E-17 T 28-03-2018 CDW54_RS03370 2be0a114fa92b54c67729fd7765ffb53 173 SUPERFAMILY SSF55729 34 170 1.62E-16 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDW54_RS03375 08cb46b25f3ad40518656d0e2e08263b 200 SUPERFAMILY SSF53335 4 178 2.43E-33 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDW54_RS03375 08cb46b25f3ad40518656d0e2e08263b 200 Gene3D G3DSA:3.40.50.150 2 193 1.5E-29 T 28-03-2018 CDW54_RS03375 08cb46b25f3ad40518656d0e2e08263b 200 Pfam PF13489 Methyltransferase domain 23 146 7.8E-16 T 28-03-2018 CDW54_RS06975 7790a3bb768b30e1b60dc3ab502ee397 134 SUPERFAMILY SSF82784 1 132 8.9E-36 T 28-03-2018 IPR003718 OsmC/Ohr family CDW54_RS06975 7790a3bb768b30e1b60dc3ab502ee397 134 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 4 131 2.4E-46 T 28-03-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 CDW54_RS06975 7790a3bb768b30e1b60dc3ab502ee397 134 Gene3D G3DSA:3.30.300.20 1 134 3.5E-34 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CDW54_RS06975 7790a3bb768b30e1b60dc3ab502ee397 134 Pfam PF02566 OsmC-like protein 37 130 1.1E-17 T 28-03-2018 IPR003718 OsmC/Ohr family CDW54_RS02680 5297584c35598e0b1998eb0560c63f96 392 Gene3D G3DSA:3.30.420.10 151 385 5.9E-5 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS02680 5297584c35598e0b1998eb0560c63f96 392 Pfam PF00872 Transposase, Mutator family 7 371 3.8E-107 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CDW54_RS10935 273535a52f36413022c3667473caa50d 160 SUPERFAMILY SSF55826 11 146 1.26E-30 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CDW54_RS10935 273535a52f36413022c3667473caa50d 160 Pfam PF04073 Aminoacyl-tRNA editing domain 43 141 8.8E-22 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CDW54_RS10935 273535a52f36413022c3667473caa50d 160 Gene3D G3DSA:3.90.960.10 2 148 9.8E-21 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CDW54_RS11580 987a2f138d6b305e45eb93ecd0da6fac 51 Gene3D G3DSA:3.40.50.720 3 50 2.9E-5 T 28-03-2018 CDW54_RS11580 987a2f138d6b305e45eb93ecd0da6fac 51 SUPERFAMILY SSF51735 4 44 1.51E-5 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS10040 d8d809fb2a74e170296b8a5b6325c600 259 Gene3D G3DSA:3.30.1890.10 37 171 8.1E-7 T 28-03-2018 CDW54_RS10040 d8d809fb2a74e170296b8a5b6325c600 259 Pfam PF13807 G-rich domain on putative tyrosine kinase 144 194 1.7E-8 T 28-03-2018 IPR032807 Tyrosine kinase, G-rich domain CDW54_RS10040 d8d809fb2a74e170296b8a5b6325c600 259 Pfam PF02706 Chain length determinant protein 3 90 5.3E-17 T 28-03-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 CDW54_RS10875 2d61059ee7132b7e673c07e9b9c500dd 97 Pfam PF04296 Protein of unknown function (DUF448) 9 81 1.8E-23 T 28-03-2018 IPR007393 Domain of unknown function DUF448 CDW54_RS10875 2d61059ee7132b7e673c07e9b9c500dd 97 Gene3D G3DSA:3.30.1230.10 1 95 5.1E-29 T 28-03-2018 IPR007393 Domain of unknown function DUF448 CDW54_RS10875 2d61059ee7132b7e673c07e9b9c500dd 97 SUPERFAMILY SSF64376 4 94 2.88E-28 T 28-03-2018 IPR007393 Domain of unknown function DUF448 CDW54_RS09010 fd14a5ef8d5162ff2c60f04241afb1ab 169 Gene3D G3DSA:3.10.450.40 120 169 0.0041 T 28-03-2018 CDW54_RS11840 6b7c8a778d8f58c79d5250ab8ada1072 80 Pfam PF04226 Transglycosylase associated protein 33 78 2.4E-11 T 28-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 CDW54_RS09600 491a5ecce619077618e1843731c769e2 322 SUPERFAMILY SSF53474 73 318 4.81E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CDW54_RS09600 491a5ecce619077618e1843731c769e2 322 Gene3D G3DSA:3.40.50.1820 53 321 2.0E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CDW54_RS09600 491a5ecce619077618e1843731c769e2 322 Pfam PF12146 Serine aminopeptidase, S33 100 218 2.7E-10 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CDW54_RS05155 4a334953c229c66f05e4598186f5a62a 148 Pfam PF11391 Protein of unknown function (DUF2798) 86 142 5.4E-7 T 28-03-2018 IPR021529 Protein of unknown function DUF2798 CDW54_RS09900 32b0a51b00e562b29c58090de8a025c3 528 PRINTS PR00447 Natural resistance-associated macrophage protein signature 149 168 1.1E-44 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CDW54_RS09900 32b0a51b00e562b29c58090de8a025c3 528 PRINTS PR00447 Natural resistance-associated macrophage protein signature 232 255 1.1E-44 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CDW54_RS09900 32b0a51b00e562b29c58090de8a025c3 528 PRINTS PR00447 Natural resistance-associated macrophage protein signature 375 392 1.1E-44 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CDW54_RS09900 32b0a51b00e562b29c58090de8a025c3 528 PRINTS PR00447 Natural resistance-associated macrophage protein signature 347 366 1.1E-44 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CDW54_RS09900 32b0a51b00e562b29c58090de8a025c3 528 PRINTS PR00447 Natural resistance-associated macrophage protein signature 121 147 1.1E-44 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CDW54_RS09900 32b0a51b00e562b29c58090de8a025c3 528 TIGRFAM TIGR01197 nramp: metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family 41 436 5.6E-103 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CDW54_RS09900 32b0a51b00e562b29c58090de8a025c3 528 Pfam PF01566 Natural resistance-associated macrophage protein 62 444 3.9E-114 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CDW54_RS03900 c8c642ab04f3221562282a5dcaebbfe2 381 Pfam PF12698 ABC-2 family transporter protein 17 367 7.6E-19 T 28-03-2018 CDW54_RS00795 2100f64062190bfae15c9f851182e4d0 108 Pfam PF12822 ECF transporter, substrate-specific component 20 103 1.0E-7 T 28-03-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 CDW54_RS10240 c8f8a7480c53cae81a1a043d313b4862 488 PIRSF PIRSF006060 1 487 1.4E-45 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CDW54_RS10240 c8f8a7480c53cae81a1a043d313b4862 488 Pfam PF13520 Amino acid permease 6 455 2.1E-29 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CDW54_RS10955 aa1556efcd2fb3ccd5dd71711fc4260c 224 SUPERFAMILY SSF52540 35 185 1.14E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS10955 aa1556efcd2fb3ccd5dd71711fc4260c 224 Gene3D G3DSA:3.40.50.300 32 197 2.9E-12 T 28-03-2018 CDW54_RS10955 aa1556efcd2fb3ccd5dd71711fc4260c 224 Pfam PF06414 Zeta toxin 26 194 1.1E-42 T 28-03-2018 IPR010488 Zeta toxin domain GO:0005524|GO:0016301 CDW54_RS08200 1138614e0af0292fbe0a8ac9ef3050a0 635 Pfam PF01431 Peptidase family M13 442 632 2.3E-62 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 CDW54_RS08200 1138614e0af0292fbe0a8ac9ef3050a0 635 SUPERFAMILY SSF55486 8 635 4.58E-185 T 28-03-2018 CDW54_RS08200 1138614e0af0292fbe0a8ac9ef3050a0 635 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 452 464 1.3E-21 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 CDW54_RS08200 1138614e0af0292fbe0a8ac9ef3050a0 635 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 434 446 1.3E-21 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 CDW54_RS08200 1138614e0af0292fbe0a8ac9ef3050a0 635 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 473 489 1.3E-21 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 CDW54_RS08200 1138614e0af0292fbe0a8ac9ef3050a0 635 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 543 554 1.3E-21 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 CDW54_RS08200 1138614e0af0292fbe0a8ac9ef3050a0 635 Pfam PF05649 Peptidase family M13 8 385 1.5E-71 T 28-03-2018 IPR008753 Peptidase M13, N-terminal domain GO:0006508 CDW54_RS08200 1138614e0af0292fbe0a8ac9ef3050a0 635 Gene3D G3DSA:3.40.390.10 1 226 3.4E-7 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CDW54_RS08200 1138614e0af0292fbe0a8ac9ef3050a0 635 Gene3D G3DSA:3.40.390.10 304 635 5.6E-93 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CDW54_RS09000 4b6beb85cf16dd0152cd2e84c1d9bc23 249 Pfam PF04973 Nicotinamide mononucleotide transporter 43 222 5.3E-30 T 28-03-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 CDW54_RS09000 4b6beb85cf16dd0152cd2e84c1d9bc23 249 TIGRFAM TIGR01528 NMN_trans_PnuC: nicotinamide mononucleotide transporter PnuC 43 230 2.3E-24 T 28-03-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 CDW54_RS08425 152906096021b3dcea5cf21de3bf5aa1 564 Pfam PF03354 Phage Terminase 70 539 4.2E-103 T 28-03-2018 IPR005021 Terminase large subunit, Lambdalikevirus-type CDW54_RS01260 819f7e06da42c9786affc3ef00a1844b 254 SUPERFAMILY SSF88713 2 254 2.67E-64 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CDW54_RS01260 819f7e06da42c9786affc3ef00a1844b 254 Gene3D G3DSA:3.20.20.370 2 254 2.8E-70 T 28-03-2018 CDW54_RS01260 819f7e06da42c9786affc3ef00a1844b 254 Pfam PF04794 YdjC-like protein 3 241 6.1E-59 T 28-03-2018 IPR006879 Carbohydrate deacetylase YdjC-like CDW54_RS01620 ae43fade8ff49d1c1e2a925c8fbbe782 106 Gene3D G3DSA:3.40.1720.10 1 95 2.2E-35 T 28-03-2018 CDW54_RS01620 ae43fade8ff49d1c1e2a925c8fbbe782 106 Pfam PF08860 Domain of unknown function (DUF1827) 1 96 1.9E-34 T 28-03-2018 IPR014959 Protein of unknown function DUF1827 CDW54_RS09150 7a07c4595c670e7757c20b5f2447a36d 183 Gene3D G3DSA:3.40.50.1950 1 174 2.2E-55 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CDW54_RS09150 7a07c4595c670e7757c20b5f2447a36d 183 SUPERFAMILY SSF52507 1 178 1.31E-58 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CDW54_RS09150 7a07c4595c670e7757c20b5f2447a36d 183 Pfam PF02441 Flavoprotein 2 175 1.3E-46 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CDW54_RS09150 7a07c4595c670e7757c20b5f2447a36d 183 TIGRFAM TIGR02113 coaC_strep: phosphopantothenoylcysteine decarboxylase 2 175 8.8E-89 T 28-03-2018 IPR011847 Phosphopantothenoylcysteine decarboxylase KEGG: 00770+4.1.1.36|MetaCyc: PWY-7851 CDW54_RS02655 a9543ca211125db69819233b9aeb58a2 88 SUPERFAMILY SSF109797 4 87 4.71E-15 T 28-03-2018 CDW54_RS02655 a9543ca211125db69819233b9aeb58a2 88 ProDom PD019933 IMMUNITY PLASMID BACTERIOCIN A ENTEROCIN ORF3 SAKACIN POSSIBLE BM1 CARNOBACTERIOCIN 1 87 6.0E-35 T 28-03-2018 CDW54_RS02655 a9543ca211125db69819233b9aeb58a2 88 Gene3D G3DSA:1.20.1440.50 5 84 5.1E-11 T 28-03-2018 IPR023130 Ta0600-like domain CDW54_RS08915 af69ebef69798586429e835ff5a5d3b7 313 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 180 307 1.3E-29 T 28-03-2018 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CDW54_RS08915 af69ebef69798586429e835ff5a5d3b7 313 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 153 1.1E-39 T 28-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CDW54_RS08915 af69ebef69798586429e835ff5a5d3b7 313 SUPERFAMILY SSF51735 1 144 5.09E-21 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS08915 af69ebef69798586429e835ff5a5d3b7 313 Gene3D G3DSA:1.10.1040.10 180 310 1.1E-31 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CDW54_RS08915 af69ebef69798586429e835ff5a5d3b7 313 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 307 1.1E-76 T 28-03-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CDW54_RS08915 af69ebef69798586429e835ff5a5d3b7 313 Gene3D G3DSA:3.40.50.720 1 179 8.9E-27 T 28-03-2018 CDW54_RS08915 af69ebef69798586429e835ff5a5d3b7 313 SUPERFAMILY SSF48179 180 307 7.14E-31 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CDW54_RS02510 17d96c90b6b11ad4e23ba6dfe193aac6 197 SUPERFAMILY SSF52096 11 193 4.75E-76 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CDW54_RS02510 17d96c90b6b11ad4e23ba6dfe193aac6 197 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 3 193 43.675 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CDW54_RS02510 17d96c90b6b11ad4e23ba6dfe193aac6 197 Gene3D G3DSA:3.90.226.10 2 194 1.7E-49 T 28-03-2018 CDW54_RS02510 17d96c90b6b11ad4e23ba6dfe193aac6 197 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 90 101 - T 28-03-2018 IPR018215 ClpP, Ser active site CDW54_RS02510 17d96c90b6b11ad4e23ba6dfe193aac6 197 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 112 125 - T 28-03-2018 IPR033135 ClpP, histidine active site CDW54_RS02510 17d96c90b6b11ad4e23ba6dfe193aac6 197 PRINTS PR00127 Clp protease catalytic subunit P signature 111 130 3.9E-52 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CDW54_RS02510 17d96c90b6b11ad4e23ba6dfe193aac6 197 PRINTS PR00127 Clp protease catalytic subunit P signature 168 187 3.9E-52 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CDW54_RS02510 17d96c90b6b11ad4e23ba6dfe193aac6 197 PRINTS PR00127 Clp protease catalytic subunit P signature 19 34 3.9E-52 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CDW54_RS02510 17d96c90b6b11ad4e23ba6dfe193aac6 197 PRINTS PR00127 Clp protease catalytic subunit P signature 90 107 3.9E-52 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CDW54_RS02510 17d96c90b6b11ad4e23ba6dfe193aac6 197 PRINTS PR00127 Clp protease catalytic subunit P signature 59 79 3.9E-52 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CDW54_RS02510 17d96c90b6b11ad4e23ba6dfe193aac6 197 Pfam PF00574 Clp protease 12 192 3.6E-88 T 28-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CDW54_RS02510 17d96c90b6b11ad4e23ba6dfe193aac6 197 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 1 191 4.8E-102 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CDW54_RS02150 d3262964fa1ab0bc4cbb6174af25fd4b 141 Pfam PF03780 Asp23 family, cell envelope-related function 15 119 3.8E-35 T 28-03-2018 IPR005531 Alkaline shock protein Asp23 CDW54_RS00630 e72727a6fcc5b9a6f500393868e90272 321 Pfam PF00005 ABC transporter 21 166 5.1E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS00630 e72727a6fcc5b9a6f500393868e90272 321 SMART SM00382 29 216 7.9E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS00630 e72727a6fcc5b9a6f500393868e90272 321 SUPERFAMILY SSF52540 4 243 5.6E-76 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS00630 e72727a6fcc5b9a6f500393868e90272 321 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS00630 e72727a6fcc5b9a6f500393868e90272 321 Gene3D G3DSA:3.40.50.300 1 275 1.3E-79 T 28-03-2018 CDW54_RS03920 bad5ea75d6dbb9c34d0a057f491914f6 75 ProSitePatterns PS00157 Ribulose bisphosphate carboxylase large chain active site. 17 25 - T 28-03-2018 IPR020878 Ribulose bisphosphate carboxylase, large chain, active site GO:0000287|GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CDW54_RS04850 8ad06eeda6455b6b0bc7ae27a7c540dc 599 SUPERFAMILY SSF55486 50 595 9.16E-98 T 28-03-2018 CDW54_RS04850 8ad06eeda6455b6b0bc7ae27a7c540dc 599 TIGRFAM TIGR02290 M3_fam_3: oligoendopeptidase, pepF/M3 family 6 594 2.0E-214 T 28-03-2018 IPR011977 Peptidase M3B, oligoendopeptidase-related clade 3 CDW54_RS04850 8ad06eeda6455b6b0bc7ae27a7c540dc 599 Gene3D G3DSA:1.10.1370.10 17 350 1.0E-4 T 28-03-2018 CDW54_RS04850 8ad06eeda6455b6b0bc7ae27a7c540dc 599 Gene3D G3DSA:1.10.1370.10 365 579 4.7E-7 T 28-03-2018 CDW54_RS04850 8ad06eeda6455b6b0bc7ae27a7c540dc 599 Pfam PF08439 Oligopeptidase F 113 178 5.9E-12 T 28-03-2018 IPR013647 Oligopeptidase F, N-terminal domain CDW54_RS04850 8ad06eeda6455b6b0bc7ae27a7c540dc 599 Pfam PF01432 Peptidase family M3 199 579 5.9E-20 T 28-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 CDW54_RS11830 04235d7fe0062463faa95d9883ab16e2 62 Pfam PF10031 Small integral membrane protein (DUF2273) 5 50 3.4E-13 T 28-03-2018 IPR018730 Protein of unknown function DUF2273 CDW54_RS03095 28b0501c28447f1d9e50f5667a8fbe23 259 Pfam PF03609 PTS system sorbose-specific iic component 2 234 3.1E-71 T 28-03-2018 IPR004700 Phosphotransferase system, mannose/fructose/sorbose family, IIC subunit GO:0009401|GO:0016021 CDW54_RS06070 ceb26ae1ca0bd29c961f0b0a876baab5 265 Hamap MF_01461 Energy-coupling factor transporter transmembrane protein EcfT [ecfT]. 2 265 38.798 T 28-03-2018 IPR024919 ECF transporter transmembrane protein EcfT GO:0005215|GO:0006810|GO:0016021 CDW54_RS06070 ceb26ae1ca0bd29c961f0b0a876baab5 265 Pfam PF02361 Cobalt transport protein 15 237 4.7E-55 T 28-03-2018 IPR003339 ABC/ECF transporter, transmembrane component CDW54_RS05405 9c166374d232693157309469684c24a9 138 Pfam PF07009 NusG domain II 19 128 8.8E-36 T 28-03-2018 IPR024045 NusG, domain 2 CDW54_RS05405 9c166374d232693157309469684c24a9 138 Gene3D G3DSA:2.60.320.10 31 138 2.9E-33 T 28-03-2018 CDW54_RS08730 68073b0f830ae0b7bbedaffa8ddba090 342 Pfam PF11797 Protein of unknown function C-terminal (DUF3324) 165 301 1.9E-35 T 28-03-2018 IPR021759 Domain of unknown function DUF3324, C-terminal CDW54_RS08730 68073b0f830ae0b7bbedaffa8ddba090 342 Pfam PF06030 Bacterial protein of unknown function (DUF916) 37 156 1.6E-34 T 28-03-2018 IPR010317 Protein of unknown function DUF916, cell surface putative CDW54_RS08730 68073b0f830ae0b7bbedaffa8ddba090 342 Gene3D G3DSA:2.60.40.1710 45 175 7.5E-4 T 28-03-2018 CDW54_RS09155 10a8b801c521ea1e9303e8ef45c005a4 245 Gene3D G3DSA:3.40.50.10300 1 244 1.6E-53 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CDW54_RS09155 10a8b801c521ea1e9303e8ef45c005a4 245 TIGRFAM TIGR02114 coaB_strep: phosphopantothenate--cysteine ligase 1 240 8.0E-80 T 28-03-2018 IPR011848 Phosphopantothenate--cysteine ligase CDW54_RS09155 10a8b801c521ea1e9303e8ef45c005a4 245 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 2 111 8.7E-22 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CDW54_RS09155 10a8b801c521ea1e9303e8ef45c005a4 245 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 134 206 1.8E-7 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CDW54_RS09155 10a8b801c521ea1e9303e8ef45c005a4 245 SUPERFAMILY SSF102645 137 239 9.55E-46 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CDW54_RS09155 10a8b801c521ea1e9303e8ef45c005a4 245 SUPERFAMILY SSF102645 1 107 9.55E-46 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CDW54_RS02025 bf33a5901740f71f7563634a531d77ea 260 SUPERFAMILY SSF55174 180 256 4.06E-33 T 28-03-2018 CDW54_RS02025 bf33a5901740f71f7563634a531d77ea 260 SUPERFAMILY SSF55174 38 128 4.06E-33 T 28-03-2018 CDW54_RS02025 bf33a5901740f71f7563634a531d77ea 260 Gene3D G3DSA:3.10.290.10 180 251 6.6E-11 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDW54_RS02025 bf33a5901740f71f7563634a531d77ea 260 Pfam PF01479 S4 domain 183 224 2.0E-7 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDW54_RS02025 bf33a5901740f71f7563634a531d77ea 260 SMART SM00363 183 243 5.0E-11 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDW54_RS08360 2555a4aa75737e708087e947750c2e39 383 Gene3D G3DSA:1.10.150.130 62 173 3.9E-20 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CDW54_RS08360 2555a4aa75737e708087e947750c2e39 383 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 67 123 1.4E-18 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CDW54_RS08360 2555a4aa75737e708087e947750c2e39 383 SUPERFAMILY SSF56349 66 369 6.18E-62 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CDW54_RS08360 2555a4aa75737e708087e947750c2e39 383 Pfam PF00589 Phage integrase family 174 367 9.3E-30 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CDW54_RS08360 2555a4aa75737e708087e947750c2e39 383 Gene3D G3DSA:1.10.443.10 174 369 2.1E-37 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CDW54_RS09060 820de1653ba34a43d0ed087fc95ad6c5 157 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 9 124 4.7E-34 T 28-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 CDW54_RS09060 820de1653ba34a43d0ed087fc95ad6c5 157 Gene3D G3DSA:3.40.50.300 1 150 7.6E-44 T 28-03-2018 CDW54_RS09060 820de1653ba34a43d0ed087fc95ad6c5 157 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 10 127 1.9E-36 T 28-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 CDW54_RS09060 820de1653ba34a43d0ed087fc95ad6c5 157 SUPERFAMILY SSF52540 20 119 7.09E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS09245 1fc2227d842f686244dc91ee2f9269ed 250 Pfam PF06738 Putative threonine/serine exporter 11 248 1.9E-71 T 28-03-2018 IPR010619 Putative threonine/serine exporter CDW54_RS12400 fe88fa30f913d93ff4938484d039abfc 303 SUPERFAMILY SSF55174 13 99 1.48E-15 T 28-03-2018 CDW54_RS12400 fe88fa30f913d93ff4938484d039abfc 303 SUPERFAMILY SSF55120 71 300 4.32E-80 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDW54_RS12400 fe88fa30f913d93ff4938484d039abfc 303 Pfam PF00849 RNA pseudouridylate synthase 87 239 2.5E-37 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDW54_RS12400 fe88fa30f913d93ff4938484d039abfc 303 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 12 298 5.8E-107 T 28-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDW54_RS12400 fe88fa30f913d93ff4938484d039abfc 303 Gene3D G3DSA:3.10.290.10 2 70 8.2E-20 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDW54_RS12400 fe88fa30f913d93ff4938484d039abfc 303 Gene3D G3DSA:3.30.2350.10 77 301 8.0E-76 T 28-03-2018 CDW54_RS12400 fe88fa30f913d93ff4938484d039abfc 303 SMART SM00363 13 77 2.9E-15 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDW54_RS12400 fe88fa30f913d93ff4938484d039abfc 303 Pfam PF01479 S4 domain 14 59 2.1E-12 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDW54_RS12400 fe88fa30f913d93ff4938484d039abfc 303 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 132 146 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDW54_RS11990 b1080e97753f38aa114c0dba9c5316d5 419 Gene3D G3DSA:3.40.190.10 161 346 1.4E-38 T 28-03-2018 CDW54_RS11990 b1080e97753f38aa114c0dba9c5316d5 419 SUPERFAMILY SSF53850 36 411 1.33E-81 T 28-03-2018 CDW54_RS11990 b1080e97753f38aa114c0dba9c5316d5 419 Gene3D G3DSA:3.40.190.10 25 160 3.0E-24 T 28-03-2018 CDW54_RS11990 b1080e97753f38aa114c0dba9c5316d5 419 Pfam PF13416 Bacterial extracellular solute-binding protein 59 358 8.3E-42 T 28-03-2018 CDW54_RS09510 d6c9273bce2ce61d09e8b2f8a869b6d4 455 SMART SM00471 59 197 1.8E-13 T 28-03-2018 IPR003607 HD/PDEase domain CDW54_RS09510 d6c9273bce2ce61d09e8b2f8a869b6d4 455 Gene3D G3DSA:1.10.3210.10 12 323 6.1E-79 T 28-03-2018 CDW54_RS09510 d6c9273bce2ce61d09e8b2f8a869b6d4 455 SUPERFAMILY SSF109604 5 449 1.05E-128 T 28-03-2018 CDW54_RS09510 d6c9273bce2ce61d09e8b2f8a869b6d4 455 Pfam PF01966 HD domain 63 190 4.0E-14 T 28-03-2018 IPR006674 HD domain CDW54_RS02795 fa3dd7bee8d1403ac26fe5a7e6b799dd 479 SUPERFAMILY SSF51445 8 478 2.05E-167 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CDW54_RS02795 fa3dd7bee8d1403ac26fe5a7e6b799dd 479 Gene3D G3DSA:3.20.20.80 6 479 1.3E-168 T 28-03-2018 CDW54_RS02795 fa3dd7bee8d1403ac26fe5a7e6b799dd 479 Pfam PF00232 Glycosyl hydrolase family 1 7 476 4.5E-175 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS02795 fa3dd7bee8d1403ac26fe5a7e6b799dd 479 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 375 383 - T 28-03-2018 IPR018120 Glycoside hydrolase family 1, active site CDW54_RS02795 fa3dd7bee8d1403ac26fe5a7e6b799dd 479 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 13 27 - T 28-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site CDW54_RS02795 fa3dd7bee8d1403ac26fe5a7e6b799dd 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 375 383 2.8E-19 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS02795 fa3dd7bee8d1403ac26fe5a7e6b799dd 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 441 453 2.8E-19 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS02795 fa3dd7bee8d1403ac26fe5a7e6b799dd 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 396 407 2.8E-19 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS02795 fa3dd7bee8d1403ac26fe5a7e6b799dd 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 292 306 2.8E-19 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS02795 fa3dd7bee8d1403ac26fe5a7e6b799dd 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 417 434 2.8E-19 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CDW54_RS09225 5d4e71f17ba1a11c39f2eca87cad68aa 309 Pfam PF03773 Predicted permease 11 305 1.4E-74 T 28-03-2018 IPR005524 Predicted permease DUF318 CDW54_RS07610 cc29cc445603dee5508e2785bf4b4004 236 Pfam PF16069 Domain of unknown function (DUF4811) 21 172 2.4E-61 T 28-03-2018 IPR032083 Protein of unknown function DUF4811 CDW54_RS00710 eb9efe2a3551a463f39a51b732ea8491 743 ProSitePatterns PS00850 Glycine radical domain signature. 713 721 - T 28-03-2018 IPR019777 Formate C-acetyltransferase glycine radical, conserved site CDW54_RS00710 eb9efe2a3551a463f39a51b732ea8491 743 PIRSF PIRSF000379 1 743 0.0 T 28-03-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 CDW54_RS00710 eb9efe2a3551a463f39a51b732ea8491 743 Gene3D G3DSA:3.20.70.20 1 743 1.6E-279 T 28-03-2018 CDW54_RS00710 eb9efe2a3551a463f39a51b732ea8491 743 Pfam PF02901 Pyruvate formate lyase-like 20 602 9.3E-201 T 28-03-2018 IPR004184 Pyruvate formate lyase domain GO:0003824 CDW54_RS00710 eb9efe2a3551a463f39a51b732ea8491 743 TIGRFAM TIGR01255 pyr_form_ly_1: formate acetyltransferase 3 743 0.0 T 28-03-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 CDW54_RS00710 eb9efe2a3551a463f39a51b732ea8491 743 SUPERFAMILY SSF51998 1 742 3.52E-273 T 28-03-2018 CDW54_RS00710 eb9efe2a3551a463f39a51b732ea8491 743 Pfam PF01228 Glycine radical 619 723 6.7E-38 T 28-03-2018 IPR001150 Glycine radical domain GO:0003824|GO:0008152 CDW54_RS07095 5ab49b67737fbe7e84d4e5e50f4dad04 105 Gene3D G3DSA:1.20.58.80 4 102 1.2E-36 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CDW54_RS07095 5ab49b67737fbe7e84d4e5e50f4dad04 105 PIRSF PIRSF000699 1 105 4.2E-36 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CDW54_RS07095 5ab49b67737fbe7e84d4e5e50f4dad04 105 SUPERFAMILY SSF46973 3 102 9.81E-36 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CDW54_RS07095 5ab49b67737fbe7e84d4e5e50f4dad04 105 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 9 101 1.1E-35 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CDW54_RS03955 e83304e00d21c75f55c5eb3dc9e26e86 299 Gene3D G3DSA:3.30.2350.10 77 299 5.0E-63 T 28-03-2018 CDW54_RS03955 e83304e00d21c75f55c5eb3dc9e26e86 299 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 130 144 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDW54_RS03955 e83304e00d21c75f55c5eb3dc9e26e86 299 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 24 295 4.5E-72 T 28-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDW54_RS03955 e83304e00d21c75f55c5eb3dc9e26e86 299 Pfam PF00849 RNA pseudouridylate synthase 86 240 1.9E-29 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDW54_RS03955 e83304e00d21c75f55c5eb3dc9e26e86 299 SUPERFAMILY SSF55120 76 296 7.68E-65 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDW54_RS05640 524f21d237122e66b533dee29a07dd0a 112 Gene3D G3DSA:3.30.110.70 55 106 1.2E-5 T 28-03-2018 IPR035439 Uncharacterised protein family UPF0145/C2CD5 Reactome: R-HSA-1445148 CDW54_RS05640 524f21d237122e66b533dee29a07dd0a 112 SUPERFAMILY SSF117782 61 105 6.54E-6 T 28-03-2018 IPR002765 Uncharacterised protein family UPF0145 CDW54_RS12150 19a3db4df4e5ed48993502e86ac77b5f 270 Pfam PF08543 Phosphomethylpyrimidine kinase 11 256 4.7E-62 T 28-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 CDW54_RS12150 19a3db4df4e5ed48993502e86ac77b5f 270 SUPERFAMILY SSF53613 1 253 6.39E-56 T 28-03-2018 IPR029056 Ribokinase-like CDW54_RS12150 19a3db4df4e5ed48993502e86ac77b5f 270 Gene3D G3DSA:3.40.1190.20 1 253 1.5E-38 T 28-03-2018 IPR029056 Ribokinase-like CDW54_RS12025 17998a9f6b767433614aeb969d97efa3 483 Gene3D G3DSA:3.90.1300.10 2 482 2.1E-102 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CDW54_RS12025 17998a9f6b767433614aeb969d97efa3 483 ProSitePatterns PS00571 Amidases signature. 144 175 - T 28-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CDW54_RS12025 17998a9f6b767433614aeb969d97efa3 483 SUPERFAMILY SSF75304 417 472 5.63E-105 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CDW54_RS12025 17998a9f6b767433614aeb969d97efa3 483 SUPERFAMILY SSF75304 3 384 5.63E-105 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CDW54_RS12025 17998a9f6b767433614aeb969d97efa3 483 Pfam PF01425 Amidase 20 463 1.9E-67 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CDW54_RS00860 c96a7ee5f4d24cb3705df50d094aab24 684 Pfam PF00999 Sodium/hydrogen exchanger family 7 407 9.1E-54 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CDW54_RS11400 7a8d00ec4da83eba605026013759b884 253 Pfam PF02698 DUF218 domain 45 171 2.4E-12 T 28-03-2018 IPR003848 Domain of unknown function DUF218 CDW54_RS11400 7a8d00ec4da83eba605026013759b884 253 Gene3D G3DSA:1.10.3620.10 143 246 1.7E-32 T 28-03-2018 CDW54_RS03170 df8de022361bc32f5b1bdd2aa87721f8 440 Pfam PF13520 Amino acid permease 9 411 3.5E-61 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CDW54_RS03170 df8de022361bc32f5b1bdd2aa87721f8 440 PIRSF PIRSF006060 1 440 2.4E-89 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CDW54_RS01210 044a517cbeb559d0c99da6f936420d1c 355 Pfam PF13483 Beta-lactamase superfamily domain 43 282 5.6E-15 T 28-03-2018 CDW54_RS01210 044a517cbeb559d0c99da6f936420d1c 355 Gene3D G3DSA:3.60.15.10 2 338 5.9E-46 T 28-03-2018 IPR001279 Metallo-beta-lactamase CDW54_RS01210 044a517cbeb559d0c99da6f936420d1c 355 SUPERFAMILY SSF56281 30 292 9.72E-25 T 28-03-2018 IPR001279 Metallo-beta-lactamase CDW54_RS01035 0c715199908229a49396327ea521832f 239 SUPERFAMILY SSF53474 11 236 2.54E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CDW54_RS01035 0c715199908229a49396327ea521832f 239 Gene3D G3DSA:3.40.50.1820 2 238 1.4E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CDW54_RS01035 0c715199908229a49396327ea521832f 239 Pfam PF00561 alpha/beta hydrolase fold 26 123 1.3E-13 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDW54_RS07535 e21252223ec8d1ddd9108428d84da792 455 Pfam PF03553 Na+/H+ antiporter family 157 443 4.6E-44 T 28-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 CDW54_RS07535 e21252223ec8d1ddd9108428d84da792 455 TIGRFAM TIGR00931 antiport_nhaC: Na+/H+ antiporter NhaC 7 446 1.4E-114 T 28-03-2018 IPR004770 Na+/H+ antiporter NhaC GO:0015297|GO:0016021 CDW54_RS02375 a95a36abe6c2bc3203eb8d4c756b2910 265 Pfam PF04536 TPM domain 28 146 2.4E-24 T 28-03-2018 IPR007621 TPM domain CDW54_RS02165 7ffe2a720bd9372fa87529806c7a6cb6 124 Pfam PF06115 Domain of unknown function (DUF956) 1 116 3.0E-56 T 28-03-2018 IPR010360 Protein of unknown function DUF956 CDW54_RS02165 7ffe2a720bd9372fa87529806c7a6cb6 124 PIRSF PIRSF021265 1 123 5.2E-55 T 28-03-2018 IPR010360 Protein of unknown function DUF956 CDW54_RS07105 6b4c1e357a0464f43edfe2125649d881 154 SUPERFAMILY SSF55729 15 147 6.75E-17 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDW54_RS07105 6b4c1e357a0464f43edfe2125649d881 154 Pfam PF13673 Acetyltransferase (GNAT) domain 50 143 7.8E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CDW54_RS07105 6b4c1e357a0464f43edfe2125649d881 154 Gene3D G3DSA:3.40.630.30 8 148 1.7E-12 T 28-03-2018 CDW54_RS05750 1b74b2509ece43d4c7df17ea1a249d7c 173 Pfam PF03729 Short repeat of unknown function (DUF308) 13 85 7.9E-9 T 28-03-2018 IPR005325 Protein of unknown function DUF308, membrane CDW54_RS05750 1b74b2509ece43d4c7df17ea1a249d7c 173 Pfam PF03729 Short repeat of unknown function (DUF308) 71 143 6.7E-8 T 28-03-2018 IPR005325 Protein of unknown function DUF308, membrane CDW54_RS05750 1b74b2509ece43d4c7df17ea1a249d7c 173 Pfam PF03729 Short repeat of unknown function (DUF308) 132 172 1.6E-7 T 28-03-2018 IPR005325 Protein of unknown function DUF308, membrane CDW54_RS05845 409354ccd7a061a557e747f88c60a0a4 520 ProSitePatterns PS00211 ABC transporters family signature. 405 419 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDW54_RS05845 409354ccd7a061a557e747f88c60a0a4 520 SMART SM00382 32 220 4.3E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS05845 409354ccd7a061a557e747f88c60a0a4 520 SUPERFAMILY SSF52540 258 494 1.02E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS05845 409354ccd7a061a557e747f88c60a0a4 520 Gene3D G3DSA:3.40.50.300 253 498 1.6E-38 T 28-03-2018 CDW54_RS05845 409354ccd7a061a557e747f88c60a0a4 520 Gene3D G3DSA:3.40.50.300 1 241 1.6E-54 T 28-03-2018 CDW54_RS05845 409354ccd7a061a557e747f88c60a0a4 520 Pfam PF00005 ABC transporter 24 172 3.2E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS05845 409354ccd7a061a557e747f88c60a0a4 520 Pfam PF00005 ABC transporter 276 432 1.9E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS05845 409354ccd7a061a557e747f88c60a0a4 520 SUPERFAMILY SSF52540 6 232 5.44E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS09595 3226caa2a4de3e8c9dea171e45a661b2 324 SUPERFAMILY SSF53590 1 306 7.19E-97 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CDW54_RS09595 3226caa2a4de3e8c9dea171e45a661b2 324 Gene3D G3DSA:3.90.245.10 1 313 2.4E-93 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CDW54_RS09595 3226caa2a4de3e8c9dea171e45a661b2 324 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 2 299 2.7E-84 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CDW54_RS09015 3407edb5c717649371cd28f144243f18 59 Gene3D G3DSA:2.10.290.10 16 56 5.1E-6 T 28-03-2018 CDW54_RS09015 3407edb5c717649371cd28f144243f18 59 Gene3D G3DSA:2.20.28.20 3 15 0.13 T 28-03-2018 CDW54_RS03410 e075ecd471fd2f4dddc6b07966450f54 232 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 7 202 3.6E-44 T 28-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 CDW54_RS03410 e075ecd471fd2f4dddc6b07966450f54 232 SUPERFAMILY SSF52317 22 195 4.31E-26 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CDW54_RS03410 e075ecd471fd2f4dddc6b07966450f54 232 Gene3D G3DSA:3.40.50.880 8 222 3.1E-17 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CDW54_RS03070 b159fd5b3c6c86367b59ab948576eb60 293 SUPERFAMILY SSF53448 4 275 7.89E-66 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDW54_RS03070 b159fd5b3c6c86367b59ab948576eb60 293 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 3 263 8.7E-113 T 28-03-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 CDW54_RS03070 b159fd5b3c6c86367b59ab948576eb60 293 Pfam PF00483 Nucleotidyl transferase 5 263 5.5E-36 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CDW54_RS03070 b159fd5b3c6c86367b59ab948576eb60 293 Gene3D G3DSA:3.90.550.10 2 276 1.7E-60 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDW54_RS05815 52e6c7ee0a109b75020717ecf7c699bc 201 Gene3D G3DSA:3.40.50.150 19 201 2.4E-29 T 28-03-2018 CDW54_RS05815 52e6c7ee0a109b75020717ecf7c699bc 201 Pfam PF05175 Methyltransferase small domain 28 197 3.1E-49 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CDW54_RS05815 52e6c7ee0a109b75020717ecf7c699bc 201 SUPERFAMILY SSF53335 6 200 1.15E-40 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDW54_RS02555 87e9369834a15342b71ef29ebbf3bced 230 Gene3D G3DSA:3.40.140.10 103 227 1.7E-44 T 28-03-2018 CDW54_RS02555 87e9369834a15342b71ef29ebbf3bced 230 SUPERFAMILY SSF47781 18 94 9.85E-10 T 28-03-2018 IPR010994 RuvA domain 2-like CDW54_RS02555 87e9369834a15342b71ef29ebbf3bced 230 Pfam PF04002 RadC-like JAB domain 109 226 9.0E-43 T 28-03-2018 IPR025657 RadC-like JAB domain CDW54_RS02555 87e9369834a15342b71ef29ebbf3bced 230 TIGRFAM TIGR00608 radc: DNA repair protein RadC 15 227 1.9E-74 T 28-03-2018 IPR001405 RadC protein CDW54_RS02555 87e9369834a15342b71ef29ebbf3bced 230 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 176 181 - T 28-03-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site CDW54_RS02555 87e9369834a15342b71ef29ebbf3bced 230 Gene3D G3DSA:1.10.150.20 48 90 6.2E-6 T 28-03-2018 CDW54_RS08355 f080133a70bb769e9a726c0acae2ad7c 463 Pfam PF01458 Uncharacterized protein family (UPF0051) 209 434 1.0E-72 T 28-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 CDW54_RS08355 f080133a70bb769e9a726c0acae2ad7c 463 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 8 454 6.0E-220 T 28-03-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 CDW54_RS08355 f080133a70bb769e9a726c0acae2ad7c 463 SUPERFAMILY SSF101960 30 460 1.29E-135 T 28-03-2018 CDW54_RS00830 cfaf01d1f3639c5bb4f67916266a6e78 298 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 56 275 9.0E-26 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CDW54_RS00830 cfaf01d1f3639c5bb4f67916266a6e78 298 Gene3D G3DSA:3.40.50.1110 47 290 3.1E-36 T 28-03-2018 CDW54_RS00830 cfaf01d1f3639c5bb4f67916266a6e78 298 SUPERFAMILY SSF52266 49 286 1.28E-38 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CDW54_RS06140 cdbfe24648d7be3ec1b7dda908c687b5 120 Pfam PF03780 Asp23 family, cell envelope-related function 9 116 3.0E-34 T 28-03-2018 IPR005531 Alkaline shock protein Asp23 CDW54_RS11415 c099e41471711a773f977ec449687f46 227 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 13 223 7.8E-48 T 28-03-2018 IPR006214 Bax inhibitor 1-related CDW54_RS05145 0ab0426b6a02562d80bcc261428e6825 171 SUPERFAMILY SSF46785 4 168 3.0E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS05145 0ab0426b6a02562d80bcc261428e6825 171 Pfam PF03551 Transcriptional regulator PadR-like family 8 75 2.4E-13 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CDW54_RS05145 0ab0426b6a02562d80bcc261428e6825 171 Gene3D G3DSA:1.10.10.10 1 87 9.0E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS05145 0ab0426b6a02562d80bcc261428e6825 171 Pfam PF10400 Virulence activator alpha C-term 88 166 1.6E-13 T 28-03-2018 IPR018309 Transcription regulator PadR, C-terminal CDW54_RS08445 0ca8c26aa593fc5f875f918e1dd6e0ab 94 TIGRFAM TIGR01560 put_DNA_pack: uncharacterized phage protein (possible DNA packaging) 4 90 1.1E-17 T 28-03-2018 IPR006450 Phage protein of unkonwn function CDW54_RS08445 0ca8c26aa593fc5f875f918e1dd6e0ab 94 Gene3D G3DSA:1.10.3230.10 1 83 4.6E-6 T 28-03-2018 CDW54_RS08445 0ca8c26aa593fc5f875f918e1dd6e0ab 94 Pfam PF05135 Phage gp6-like head-tail connector protein 1 87 2.4E-15 T 28-03-2018 IPR021146 Phage gp6-like head-tail connector protein CDW54_RS05780 5be70c89cc05345d0e26247e0941e206 192 Pfam PF06736 Protein of unknown function (DUF1211) 5 89 1.3E-28 T 28-03-2018 IPR010617 Endosomal/lysomomal potassium channel TMEM175 GO:0005267 CDW54_RS05400 799f113285b82e4a7b8169d33df4b2bb 188 PIRSF PIRSF027391 1 177 3.5E-72 T 28-03-2018 IPR014535 Predicted heptaprenyl diphosphate synthase, component I CDW54_RS05400 799f113285b82e4a7b8169d33df4b2bb 188 Pfam PF07456 Heptaprenyl diphosphate synthase component I 13 159 2.3E-49 T 28-03-2018 IPR010898 Heptaprenyl diphosphate synthase component I CDW54_RS09040 ca04652bb7645481311fc7f9de9a9cdd 171 SUPERFAMILY SSF54518 4 152 1.2E-13 T 28-03-2018 IPR025659 Tubby C-terminal-like domain CDW54_RS11385 8ac676fc61a96663a95ace0afa99c539 243 Pfam PF00149 Calcineurin-like phosphoesterase 5 187 6.2E-12 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CDW54_RS11385 8ac676fc61a96663a95ace0afa99c539 243 SUPERFAMILY SSF56300 5 224 6.01E-36 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CDW54_RS11385 8ac676fc61a96663a95ace0afa99c539 243 Gene3D G3DSA:3.60.21.10 2 241 6.3E-35 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CDW54_RS07730 6ef13339075249ee79450140144c0349 392 Pfam PF00872 Transposase, Mutator family 7 371 5.4E-108 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CDW54_RS07730 6ef13339075249ee79450140144c0349 392 Gene3D G3DSA:3.30.420.10 151 386 6.8E-5 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDW54_RS08665 6be85f33e5bc4213555416d5f4da1392 37 SUPERFAMILY SSF53041 1 36 9.55E-6 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CDW54_RS08665 6be85f33e5bc4213555416d5f4da1392 37 Gene3D G3DSA:3.40.50.1390 1 37 1.7E-5 T 28-03-2018 CDW54_RS12215 72e47df3da9852c7c26335ce9ca8807b 343 SUPERFAMILY SSF55347 126 278 1.33E-18 T 28-03-2018 CDW54_RS12215 72e47df3da9852c7c26335ce9ca8807b 343 Gene3D G3DSA:3.40.50.720 1 132 2.8E-26 T 28-03-2018 CDW54_RS12215 72e47df3da9852c7c26335ce9ca8807b 343 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 132 231 8.4E-7 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CDW54_RS12215 72e47df3da9852c7c26335ce9ca8807b 343 Gene3D G3DSA:3.30.360.10 133 342 1.6E-25 T 28-03-2018 CDW54_RS12215 72e47df3da9852c7c26335ce9ca8807b 343 SUPERFAMILY SSF51735 3 179 8.45E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain CDW54_RS12215 72e47df3da9852c7c26335ce9ca8807b 343 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 115 1.0E-17 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CDW54_RS10880 9cbd813254538619f0ca94fc1d2d2ed2 103 Gene3D G3DSA:3.30.1330.30 7 102 1.1E-15 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CDW54_RS10880 9cbd813254538619f0ca94fc1d2d2ed2 103 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 8 96 1.4E-17 T 28-03-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 CDW54_RS10880 9cbd813254538619f0ca94fc1d2d2ed2 103 SUPERFAMILY SSF55315 7 102 3.14E-24 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CDW54_RS12395 9cf95e321601643c400efeb44fe34c80 179 SUPERFAMILY SSF53271 5 172 2.1E-43 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CDW54_RS12395 9cf95e321601643c400efeb44fe34c80 179 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 3 176 38.249 T 28-03-2018 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CDW54_RS12395 9cf95e321601643c400efeb44fe34c80 179 Gene3D G3DSA:3.40.50.2020 1 179 9.4E-39 T 28-03-2018 CDW54_RS12395 9cf95e321601643c400efeb44fe34c80 179 Pfam PF00156 Phosphoribosyl transferase domain 4 149 8.1E-23 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CDW54_RS02770 80eb2850742f2741fd7539881a7ffb6a 78 Gene3D G3DSA:3.40.1160.10 2 73 6.8E-4 T 28-03-2018 CDW54_RS02770 80eb2850742f2741fd7539881a7ffb6a 78 Pfam PF00696 Amino acid kinase family 3 71 9.2E-6 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CDW54_RS04445 255d2aef126af46617aac42bc0ff5778 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 300 1.3E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS04445 255d2aef126af46617aac42bc0ff5778 306 SUPERFAMILY SSF161098 16 305 3.53E-54 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS04445 255d2aef126af46617aac42bc0ff5778 306 Gene3D G3DSA:1.10.3720.10 71 301 2.8E-39 T 28-03-2018 CDW54_RS03395 fbad7efca9d89e79634203322b2b4dbc 245 Pfam PF02677 Uncharacterized BCR, COG1636 38 218 2.1E-62 T 28-03-2018 IPR003828 Probable epoxyqueuosine reductase QueH CDW54_RS08695 49eabef421a76f9fb72613e482831a1d 678 Pfam PF07242 Protein of unknown function (DUF1430) 578 677 2.2E-7 T 28-03-2018 IPR006541 Bacteriocin-associated integral membrane protein CDW54_RS11910 8f4d58464d30e27e5e624420f6816ff5 383 Gene3D G3DSA:1.20.91.10 226 309 3.2E-17 T 28-03-2018 CDW54_RS11910 8f4d58464d30e27e5e624420f6816ff5 383 Pfam PF00999 Sodium/hydrogen exchanger family 7 378 7.5E-87 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CDW54_RS11910 8f4d58464d30e27e5e624420f6816ff5 383 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 11 283 2.5E-86 T 28-03-2018 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 CDW54_RS02945 c76e15ec22c9a2abe0e11946733b4a31 461 Pfam PF00149 Calcineurin-like phosphoesterase 6 206 3.3E-11 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CDW54_RS02945 c76e15ec22c9a2abe0e11946733b4a31 461 ProSitePatterns PS00785 5'-nucleotidase signature 1. 4 16 - T 28-03-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CDW54_RS02945 c76e15ec22c9a2abe0e11946733b4a31 461 PIRSF PIRSF036361 1 459 7.2E-182 T 28-03-2018 IPR011240 Phosphoesterase-related protein YunD CDW54_RS02945 c76e15ec22c9a2abe0e11946733b4a31 461 Pfam PF02872 5'-nucleotidase, C-terminal domain 290 423 2.5E-7 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CDW54_RS02945 c76e15ec22c9a2abe0e11946733b4a31 461 Gene3D G3DSA:3.90.780.10 291 461 2.0E-17 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CDW54_RS02945 c76e15ec22c9a2abe0e11946733b4a31 461 SUPERFAMILY SSF56300 3 277 2.23E-66 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CDW54_RS02945 c76e15ec22c9a2abe0e11946733b4a31 461 Gene3D G3DSA:3.60.21.10 2 284 1.1E-57 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CDW54_RS02945 c76e15ec22c9a2abe0e11946733b4a31 461 PRINTS PR01607 Apyrase family signature 217 237 3.2E-18 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CDW54_RS02945 c76e15ec22c9a2abe0e11946733b4a31 461 PRINTS PR01607 Apyrase family signature 2 20 3.2E-18 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CDW54_RS02945 c76e15ec22c9a2abe0e11946733b4a31 461 PRINTS PR01607 Apyrase family signature 170 187 3.2E-18 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CDW54_RS02945 c76e15ec22c9a2abe0e11946733b4a31 461 PRINTS PR01607 Apyrase family signature 189 212 3.2E-18 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CDW54_RS02945 c76e15ec22c9a2abe0e11946733b4a31 461 PRINTS PR01607 Apyrase family signature 408 427 3.2E-18 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CDW54_RS02945 c76e15ec22c9a2abe0e11946733b4a31 461 SUPERFAMILY SSF55816 283 460 3.27E-21 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CDW54_RS12095 4da7cc07600b63b7bd5f28e8e50cd9e8 311 Pfam PF01545 Cation efflux family 13 219 8.2E-30 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CDW54_RS12095 4da7cc07600b63b7bd5f28e8e50cd9e8 311 Gene3D G3DSA:1.20.1510.10 10 221 1.5E-29 T 28-03-2018 CDW54_RS12095 4da7cc07600b63b7bd5f28e8e50cd9e8 311 SUPERFAMILY SSF161111 8 223 2.62E-33 T 28-03-2018 CDW54_RS12095 4da7cc07600b63b7bd5f28e8e50cd9e8 311 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 12 301 5.8E-33 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CDW54_RS07365 3d41ac4417e40003d16d08d829480ac0 363 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 14 335 3.2E-70 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CDW54_RS07365 3d41ac4417e40003d16d08d829480ac0 363 SUPERFAMILY SSF51395 4 336 2.69E-93 T 28-03-2018 CDW54_RS07365 3d41ac4417e40003d16d08d829480ac0 363 Gene3D G3DSA:3.20.20.70 1 348 3.1E-97 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDW54_RS12230 b05c47e78cab6f8a15b02949441e9322 94 Gene3D G3DSA:3.40.50.2300 1 93 5.3E-16 T 28-03-2018 CDW54_RS12230 b05c47e78cab6f8a15b02949441e9322 94 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 2 87 5.8E-13 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CDW54_RS12230 b05c47e78cab6f8a15b02949441e9322 94 SUPERFAMILY SSF52794 1 91 1.36E-17 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CDW54_RS09820 3323adc38e3b455991d5d06d0038513f 522 Pfam PF13349 Putative adhesin 269 516 5.6E-14 T 28-03-2018 IPR025164 Putative adhesin CDW54_RS09820 3323adc38e3b455991d5d06d0038513f 522 Gene3D G3DSA:3.40.50.300 3 512 1.3E-7 T 28-03-2018 CDW54_RS12310 cf36bc42bbf9182c9ff9199a725f8908 349 Pfam PF04392 ABC transporter substrate binding protein 44 334 2.7E-101 T 28-03-2018 IPR007487 ABC transporter, substrate-binding protein CDW54_RS12310 cf36bc42bbf9182c9ff9199a725f8908 349 SUPERFAMILY SSF53822 41 265 1.09E-18 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CDW54_RS12310 cf36bc42bbf9182c9ff9199a725f8908 349 Gene3D G3DSA:3.40.50.2300 166 303 4.2E-24 T 28-03-2018 CDW54_RS12310 cf36bc42bbf9182c9ff9199a725f8908 349 Gene3D G3DSA:3.40.50.2300 40 165 1.3E-22 T 28-03-2018 CDW54_RS10200 ab8196b4284d687b851b8b20fc364e80 396 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 115 136 1.3E-14 T 28-03-2018 CDW54_RS10200 ab8196b4284d687b851b8b20fc364e80 396 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 93 113 1.3E-14 T 28-03-2018 CDW54_RS10200 ab8196b4284d687b851b8b20fc364e80 396 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 162 186 1.3E-14 T 28-03-2018 CDW54_RS10200 ab8196b4284d687b851b8b20fc364e80 396 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 198 221 1.3E-14 T 28-03-2018 CDW54_RS10200 ab8196b4284d687b851b8b20fc364e80 396 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 229 253 1.3E-14 T 28-03-2018 CDW54_RS10200 ab8196b4284d687b851b8b20fc364e80 396 Gene3D G3DSA:3.90.1150.10 273 396 2.2E-31 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDW54_RS10200 ab8196b4284d687b851b8b20fc364e80 396 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 235 248 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CDW54_RS10200 ab8196b4284d687b851b8b20fc364e80 396 Gene3D G3DSA:3.40.640.10 44 272 1.1E-48 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDW54_RS10200 ab8196b4284d687b851b8b20fc364e80 396 SUPERFAMILY SSF53383 2 391 1.86E-112 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDW54_RS10200 ab8196b4284d687b851b8b20fc364e80 396 Pfam PF00155 Aminotransferase class I and II 31 386 1.8E-74 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CDW54_RS10735 56ad300744204426430f0f4e9fd37571 55 Pfam PF11240 Protein of unknown function (DUF3042) 1 54 3.4E-28 T 28-03-2018 IPR021402 Protein of unknown function DUF3042 CDW54_RS09330 4037e49fe6ee71f17dee546d55330945 519 Pfam PF05043 Mga helix-turn-helix domain 99 178 6.8E-21 T 28-03-2018 IPR007737 Mga helix-turn-helix domain CDW54_RS09330 4037e49fe6ee71f17dee546d55330945 519 Gene3D G3DSA:1.10.10.10 24 91 3.1E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS09330 4037e49fe6ee71f17dee546d55330945 519 Gene3D G3DSA:1.10.10.10 110 173 3.4E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS10920 816f4526ce2b37b56eab617a6aadf77e 283 Pfam PF06800 Sugar transport protein 4 283 3.0E-93 T 28-03-2018 IPR010651 Sugar transport protein GO:0015144|GO:0016021|GO:0034219 CDW54_RS10920 816f4526ce2b37b56eab617a6aadf77e 283 SUPERFAMILY SSF103481 187 280 1.02E-6 T 28-03-2018 CDW54_RS10920 816f4526ce2b37b56eab617a6aadf77e 283 SUPERFAMILY SSF103481 41 129 6.67E-5 T 28-03-2018 CDW54_RS00230 d756118f87116dea4e3af64eb17f80f8 81 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 16 74 9.1E-8 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CDW54_RS00230 d756118f87116dea4e3af64eb17f80f8 81 Gene3D G3DSA:3.40.50.1110 10 79 6.7E-9 T 28-03-2018 CDW54_RS00230 d756118f87116dea4e3af64eb17f80f8 81 SUPERFAMILY SSF52266 18 75 2.66E-11 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CDW54_RS06880 dfee6e2a80cd7df7c32cbeb8b1d5f4e2 302 Pfam PF01609 Transposase DDE domain 115 281 2.4E-23 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDW54_RS02850 cfb251d45d58f350070e429888878570 344 Pfam PF01263 Aldose 1-epimerase 18 330 7.7E-59 T 28-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 CDW54_RS02850 cfb251d45d58f350070e429888878570 344 ProSitePatterns PS00545 Aldose 1-epimerase putative active site. 167 176 - T 28-03-2018 IPR018052 Aldose 1-epimerase, conserved site KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 CDW54_RS02850 cfb251d45d58f350070e429888878570 344 SUPERFAMILY SSF74650 13 332 7.53E-79 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CDW54_RS02850 cfb251d45d58f350070e429888878570 344 Gene3D G3DSA:2.70.98.10 10 343 2.2E-76 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CDW54_RS07270 30176cc8fa9b0b2421ae4782673f604b 135 Gene3D G3DSA:1.10.150.200 31 121 8.2E-9 T 28-03-2018 CDW54_RS09230 2e09fbfa18266acc628c3d90e3b17a53 280 Pfam PF09323 Domain of unknown function (DUF1980) 1 185 6.3E-64 T 28-03-2018 IPR015402 Protein of unknown function DUF1980 CDW54_RS09230 2e09fbfa18266acc628c3d90e3b17a53 280 TIGRFAM TIGR03943 TIGR03943: TIGR03943 family protein 19 275 2.9E-59 T 28-03-2018 IPR015402 Protein of unknown function DUF1980 CDW54_RS03335 aab6b8efc3b498f3c077bf172a9e221b 315 SUPERFAMILY SSF53474 42 313 9.1E-64 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CDW54_RS03335 aab6b8efc3b498f3c077bf172a9e221b 315 Gene3D G3DSA:3.40.50.1820 5 314 2.5E-54 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CDW54_RS03335 aab6b8efc3b498f3c077bf172a9e221b 315 Pfam PF07859 alpha/beta hydrolase fold 81 289 2.0E-65 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CDW54_RS12200 c0f25a3bbd952ac8f23f9c6e237b5fa8 261 Gene3D G3DSA:3.40.50.2300 172 260 8.1E-9 T 28-03-2018 CDW54_RS07795 1959b73256258f30671c573a838452a1 426 Gene3D G3DSA:3.30.565.10 274 415 1.5E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS07795 1959b73256258f30671c573a838452a1 426 Gene3D G3DSA:1.10.287.130 208 273 4.7E-11 T 28-03-2018 CDW54_RS07795 1959b73256258f30671c573a838452a1 426 SUPERFAMILY SSF55874 288 422 1.26E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS07795 1959b73256258f30671c573a838452a1 426 Pfam PF14501 GHKL domain 321 424 1.7E-18 T 28-03-2018 IPR032834 Sensor histidine kinase NatK, C-terminal domain CDW54_RS05365 b4b8955cf29e788a3b734f7605d7a929 302 Gene3D G3DSA:1.10.3470.10 1 285 6.1E-36 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CDW54_RS05365 b4b8955cf29e788a3b734f7605d7a929 302 Pfam PF02653 Branched-chain amino acid transport system / permease component 9 279 1.0E-32 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CDW54_RS06295 3fd7b2ae81c7fea366d7d748995ab5ab 136 Pfam PF03788 LrgA family 15 106 1.8E-25 T 28-03-2018 IPR005538 LrgA/CidA family GO:0016021 CDW54_RS11485 d7943723fdd1ab68de196e57e0c1fa3f 348 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 11 320 2.1E-19 T 28-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD CDW54_RS12185 28d7e48b6a207d345ff0bdf30828adc6 357 Pfam PF02687 FtsX-like permease family 268 351 5.9E-7 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CDW54_RS12185 28d7e48b6a207d345ff0bdf30828adc6 357 Pfam PF12704 MacB-like periplasmic core domain 18 181 5.5E-13 T 28-03-2018 IPR025857 MacB-like periplasmic core domain CDW54_RS11435 dda5978bf76012793dda7f0a7e795571 110 Gene3D G3DSA:1.10.1470.10 2 68 2.9E-4 T 28-03-2018 IPR008462 CsbD-like domain CDW54_RS10615 ff95ad594d57111b0bdf9eb469ec4f09 198 Pfam PF09335 SNARE associated Golgi protein 68 185 3.6E-21 T 28-03-2018 IPR032816 SNARE associated Golgi protein CDW54_RS04290 67f232e0e391d1d2441cdbec334aa1dd 136 Pfam PF13273 Protein of unknown function (DUF4064) 2 106 4.9E-12 T 28-03-2018 IPR025273 Domain of unknown function DUF4064 CDW54_RS01160 e6a3950b70db1841f44da5974d97198a 324 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 122 1.3E-10 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CDW54_RS01160 e6a3950b70db1841f44da5974d97198a 324 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 159 272 7.1E-5 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CDW54_RS01160 e6a3950b70db1841f44da5974d97198a 324 SUPERFAMILY SSF54593 4 302 8.7E-46 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDW54_RS01160 e6a3950b70db1841f44da5974d97198a 324 Gene3D G3DSA:3.10.180.10 152 319 1.1E-22 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDW54_RS01160 e6a3950b70db1841f44da5974d97198a 324 Gene3D G3DSA:3.10.180.10 1 145 1.7E-19 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDW54_RS07705 52bdb35475802ebc68ca40be6e87f5ac 250 Gene3D G3DSA:3.40.50.300 1 237 3.7E-67 T 28-03-2018 CDW54_RS07705 52bdb35475802ebc68ca40be6e87f5ac 250 Pfam PF00005 ABC transporter 25 173 3.2E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDW54_RS07705 52bdb35475802ebc68ca40be6e87f5ac 250 SUPERFAMILY SSF52540 4 229 1.55E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDW54_RS07705 52bdb35475802ebc68ca40be6e87f5ac 250 SMART SM00382 34 231 3.6E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CDW54_RS11795 5b5d57e79b3fed47f63e8ca3986403c1 300 Pfam PF03780 Asp23 family, cell envelope-related function 140 246 2.0E-29 T 28-03-2018 IPR005531 Alkaline shock protein Asp23 CDW54_RS05070 6dd530f992e553cd0aa8e843e3d4ebf1 176 Pfam PF05991 YacP-like NYN domain 6 166 1.0E-55 T 28-03-2018 IPR010298 Protein of unknown function DUF901 CDW54_RS05070 6dd530f992e553cd0aa8e843e3d4ebf1 176 Gene3D G3DSA:3.40.50.1010 1 73 0.018 T 28-03-2018 IPR029060 PIN domain-like CDW54_RS05415 9223b7679fb5b6d25650700839bc7bf7 311 SMART SM00900 198 294 1.5E-10 T 28-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 CDW54_RS05415 9223b7679fb5b6d25650700839bc7bf7 311 SMART SM00900 76 167 1.2E-11 T 28-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 CDW54_RS05415 9223b7679fb5b6d25650700839bc7bf7 311 Gene3D G3DSA:2.60.40.810 136 250 0.0035 T 28-03-2018 CDW54_RS05415 9223b7679fb5b6d25650700839bc7bf7 311 Gene3D G3DSA:2.60.40.810 24 128 0.0032 T 28-03-2018 CDW54_RS05415 9223b7679fb5b6d25650700839bc7bf7 311 Pfam PF04205 FMN-binding domain 82 164 1.3E-4 T 28-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 CDW54_RS12235 1cdbdfafc7ae26b6315325102af59715 457 Pfam PF03611 PTS system sugar-specific permease component 11 407 8.2E-136 T 28-03-2018 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 CDW54_RS09500 e5d49f37187b3c38180c704b93f27455 147 PRINTS PR00502 NUDIX hydrolase family signature 55 70 4.8E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CDW54_RS09500 e5d49f37187b3c38180c704b93f27455 147 PRINTS PR00502 NUDIX hydrolase family signature 41 55 4.8E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CDW54_RS09500 e5d49f37187b3c38180c704b93f27455 147 Gene3D G3DSA:3.90.79.10 1 146 5.5E-24 T 28-03-2018 CDW54_RS09500 e5d49f37187b3c38180c704b93f27455 147 Pfam PF00293 NUDIX domain 18 133 1.1E-12 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CDW54_RS09500 e5d49f37187b3c38180c704b93f27455 147 ProSitePatterns PS00893 Nudix box signature. 46 67 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CDW54_RS09500 e5d49f37187b3c38180c704b93f27455 147 SUPERFAMILY SSF55811 11 143 5.96E-26 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CDW54_RS08375 677ec0b441ed290609ad9348df2dfc38 90 Gene3D G3DSA:1.10.10.10 39 89 3.2E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS05855 dd4c3dd13472b179cb2d9e6ea6631a9f 318 Gene3D G3DSA:1.10.3470.10 1 306 2.2E-43 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CDW54_RS05855 dd4c3dd13472b179cb2d9e6ea6631a9f 318 Pfam PF02653 Branched-chain amino acid transport system / permease component 11 297 3.9E-39 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CDW54_RS06910 203d4708ba0c6058a55b1de785ebe28d 478 Gene3D G3DSA:1.10.10.10 7 70 5.7E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS06980 70256d44f667ea595c47293cc7420916 347 SUPERFAMILY SSF50969 85 298 5.18E-5 T 28-03-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like CDW54_RS06980 70256d44f667ea595c47293cc7420916 347 Gene3D G3DSA:2.130.10.10 51 265 5.5E-5 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CDW54_RS12105 8becdc7354f620ffcfbaf772755d80b2 105 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 7 102 2.4E-22 T 28-03-2018 IPR008407 Branched-chain amino acid transport, AzlD CDW54_RS07260 970d747fa35d603ce74e9a321107cc81 100 Gene3D G3DSA:3.40.50.2300 1 99 2.7E-20 T 28-03-2018 CDW54_RS07260 970d747fa35d603ce74e9a321107cc81 100 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 5 90 1.6E-15 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CDW54_RS07260 970d747fa35d603ce74e9a321107cc81 100 SUPERFAMILY SSF52794 1 95 4.71E-20 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CDW54_RS06275 5e63a7d18e50d5bd628d77fc950029c5 158 Pfam PF05043 Mga helix-turn-helix domain 82 151 1.0E-11 T 28-03-2018 IPR007737 Mga helix-turn-helix domain CDW54_RS06275 5e63a7d18e50d5bd628d77fc950029c5 158 Gene3D G3DSA:1.10.10.10 7 72 0.32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS06275 5e63a7d18e50d5bd628d77fc950029c5 158 Gene3D G3DSA:1.10.10.10 84 156 5.3E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS11960 66e8ce8f4168bba6128a767141df9e12 359 Pfam PF01594 AI-2E family transporter 31 345 9.0E-43 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like CDW54_RS02170 ef85fb54436cdc425e6ec717f072dc5b 304 Pfam PF03613 PTS system mannose/fructose/sorbose family IID component 7 304 4.8E-117 T 28-03-2018 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 CDW54_RS02170 ef85fb54436cdc425e6ec717f072dc5b 304 TIGRFAM TIGR00828 EIID-AGA: PTS system, mannose/fructose/sorbose family, IID component 7 219 5.3E-89 T 28-03-2018 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 CDW54_RS03090 a873ca64ad867e15476759cc23b192c2 273 Pfam PF03613 PTS system mannose/fructose/sorbose family IID component 10 273 8.7E-105 T 28-03-2018 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 CDW54_RS11760 30d794d732806ff93685112b197289a5 285 SUPERFAMILY SSF53448 8 272 8.44E-68 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDW54_RS11760 30d794d732806ff93685112b197289a5 285 Pfam PF01501 Glycosyl transferase family 8 10 258 4.5E-52 T 28-03-2018 IPR002495 Glycosyl transferase, family 8 GO:0016757 CDW54_RS11760 30d794d732806ff93685112b197289a5 285 Gene3D G3DSA:3.90.550.10 8 281 1.2E-58 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDW54_RS11330 6a8e87d3883106594d12d8a79b60ec78 227 Pfam PF07556 Protein of unknown function (DUF1538) 16 225 5.6E-64 T 28-03-2018 IPR011435 Protein of unknown function DUF1538 CDW54_RS06490 97761650fda85f9da98aaec70d7b2360 88 Pfam PF04226 Transglycosylase associated protein 34 79 6.3E-13 T 28-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 CDW54_RS10225 34c76239694eb62f2fd4d7db3448089e 119 Pfam PF03733 Inner membrane component domain 4 54 8.8E-18 T 28-03-2018 IPR005185 Inner membrane component domain CDW54_RS10225 34c76239694eb62f2fd4d7db3448089e 119 Pfam PF03733 Inner membrane component domain 66 115 1.4E-20 T 28-03-2018 IPR005185 Inner membrane component domain CDW54_RS10225 34c76239694eb62f2fd4d7db3448089e 119 PIRSF PIRSF028777 1 119 1.1E-46 T 28-03-2018 IPR031308 Uncharacterised conserved protein UCP028777 CDW54_RS00695 a3392c9dad6989e7e135e8b1b8b79089 298 Gene3D G3DSA:1.10.10.10 26 80 4.6E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS00695 a3392c9dad6989e7e135e8b1b8b79089 298 Pfam PF08820 Domain of unknown function (DUF1803) 10 127 9.4E-29 T 28-03-2018 IPR014924 Protein of unknown function DUF1803 CDW54_RS03040 19c96a5bd26ee98fbb1efd5b371da603 67 SUPERFAMILY SSF69047 11 61 1.03E-6 T 28-03-2018 IPR008462 CsbD-like domain CDW54_RS03040 19c96a5bd26ee98fbb1efd5b371da603 67 Pfam PF05532 CsbD-like 10 58 3.6E-12 T 28-03-2018 IPR008462 CsbD-like domain CDW54_RS03040 19c96a5bd26ee98fbb1efd5b371da603 67 Gene3D G3DSA:1.10.1470.10 4 67 6.8E-11 T 28-03-2018 IPR008462 CsbD-like domain CDW54_RS08980 cadf31dd0895eb5e722e68f8b4f39bfa 228 Pfam PF06149 Protein of unknown function (DUF969) 4 218 3.8E-75 T 28-03-2018 IPR010374 Protein of unknown function DUF969 CDW54_RS01055 a25f2a7f3c1b4cd6c331d8f2cb0d30a3 334 Pfam PF04245 37-kD nucleoid-associated bacterial protein 9 329 3.9E-56 T 28-03-2018 IPR007358 Nucleoid-associated protein NdpA GO:0009295 CDW54_RS10055 64f5c6d33c54762895e69d509f25f7b6 229 Pfam PF02397 Bacterial sugar transferase 35 223 1.1E-67 T 28-03-2018 IPR003362 Bacterial sugar transferase CDW54_RS02990 8fd36eedb148f73b08c6477398b03a5f 235 Pfam PF04298 Putative neutral zinc metallopeptidase 14 229 6.3E-87 T 28-03-2018 IPR007395 Putative neutral zinc metallopeptidase CDW54_RS01420 3986a7bdc3c0d15ec56827f87d54d338 61 Pfam PF11151 Protein of unknown function (DUF2929) 1 55 6.4E-24 T 28-03-2018 IPR021324 Protein of unknown function DUF2929 CDW54_RS08420 f77a8402e98478d9f6dd5b5df4bf2483 157 TIGRFAM TIGR01558 sm_term_P27: putative phage terminase, small subunit, P27 family 40 153 1.8E-25 T 28-03-2018 IPR006448 Putative phage terminase, small subunit, P27 family CDW54_RS08420 f77a8402e98478d9f6dd5b5df4bf2483 157 Pfam PF05119 Phage terminase, small subunit 48 141 1.7E-24 T 28-03-2018 IPR006448 Putative phage terminase, small subunit, P27 family CDW54_RS10005 aab7adced97010687ab4131db9e32936 133 Pfam PF01219 Prokaryotic diacylglycerol kinase 22 123 3.3E-33 T 28-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 CDW54_RS10005 aab7adced97010687ab4131db9e32936 133 Gene3D G3DSA:1.10.3830.10 12 125 7.2E-38 T 28-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 CDW54_RS04805 c729220ec90de5ade43d188b2d45ba10 141 Pfam PF04977 Septum formation initiator 45 121 1.9E-15 T 28-03-2018 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 CDW54_RS01490 b26a316294891967c431fe2dd72e7fac 246 SUPERFAMILY SSF53335 3 245 2.79E-48 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDW54_RS01490 b26a316294891967c431fe2dd72e7fac 246 Gene3D G3DSA:3.40.50.150 3 135 2.8E-22 T 28-03-2018 CDW54_RS01490 b26a316294891967c431fe2dd72e7fac 246 Gene3D G3DSA:2.20.25.110 140 204 7.0E-17 T 28-03-2018 CDW54_RS01490 b26a316294891967c431fe2dd72e7fac 246 Pfam PF13649 Methyltransferase domain 37 132 1.1E-18 T 28-03-2018 CDW54_RS00890 6740745ca406b1362076122138eef9e3 193 Hamap MF_00760 UPF0302 protein . 1 176 24.463 T 28-03-2018 IPR011188 Uncharacterised protein family UPF0302 CDW54_RS00890 6740745ca406b1362076122138eef9e3 193 PIRSF PIRSF007165 1 183 2.1E-59 T 28-03-2018 IPR011188 Uncharacterised protein family UPF0302 CDW54_RS00890 6740745ca406b1362076122138eef9e3 193 Pfam PF08858 IDEAL domain 139 172 5.8E-10 T 28-03-2018 IPR014957 IDEAL domain CDW54_RS00890 6740745ca406b1362076122138eef9e3 193 SMART SM00914 137 173 8.4E-6 T 28-03-2018 IPR014957 IDEAL domain CDW54_RS00890 6740745ca406b1362076122138eef9e3 193 Pfam PF08864 UPF0302 domain 7 111 1.5E-38 T 28-03-2018 IPR014963 Uncharacterised domain UPF0302, N-terminal CDW54_RS01050 d337d01d5fd4b2924e764138846115d6 118 Pfam PF06486 Protein of unknown function (DUF1093) 24 104 4.5E-27 T 28-03-2018 IPR006542 Protein of unknown function DUF1093 CDW54_RS01050 d337d01d5fd4b2924e764138846115d6 118 SUPERFAMILY SSF159121 21 117 4.84E-29 T 28-03-2018 IPR006542 Protein of unknown function DUF1093 CDW54_RS01050 d337d01d5fd4b2924e764138846115d6 118 TIGRFAM TIGR01655 yxeA_fam: conserved hypothetical protein 1 115 4.7E-21 T 28-03-2018 IPR006542 Protein of unknown function DUF1093 CDW54_RS11125 71e88ec88825e89c53e8468d78afe2bc 219 Pfam PF06271 RDD family 73 200 7.5E-23 T 28-03-2018 IPR010432 RDD CDW54_RS07515 0daa36c8ca0d74d548a3ee15dd528740 433 SUPERFAMILY SSF88713 231 365 5.28E-17 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CDW54_RS07515 0daa36c8ca0d74d548a3ee15dd528740 433 SUPERFAMILY SSF88713 135 194 5.28E-17 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CDW54_RS07515 0daa36c8ca0d74d548a3ee15dd528740 433 Pfam PF01522 Polysaccharide deacetylase 285 348 5.3E-6 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CDW54_RS07515 0daa36c8ca0d74d548a3ee15dd528740 433 Gene3D G3DSA:3.20.20.370 87 427 4.3E-28 T 28-03-2018 CDW54_RS01485 c0a9958b67f6c93d60fffd184203b4d3 383 Gene3D G3DSA:3.40.50.620 1 231 1.4E-57 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDW54_RS01485 c0a9958b67f6c93d60fffd184203b4d3 383 Hamap MF_01539 UPF0348 protein . 2 382 38.382 T 28-03-2018 IPR008513 Uncharacterised protein family UPF0348 CDW54_RS01485 c0a9958b67f6c93d60fffd184203b4d3 383 Pfam PF05636 HIGH Nucleotidyl Transferase 1 367 3.6E-128 T 28-03-2018 IPR008513 Uncharacterised protein family UPF0348 CDW54_RS01485 c0a9958b67f6c93d60fffd184203b4d3 383 SUPERFAMILY SSF52374 1 106 5.63E-22 T 28-03-2018 CDW54_RS01485 c0a9958b67f6c93d60fffd184203b4d3 383 SUPERFAMILY SSF52374 152 226 5.63E-22 T 28-03-2018 CDW54_RS06110 5d5e085ef28163d9afcb100e9e0140ce 112 Pfam PF06953 Arsenical resistance operon trans-acting repressor ArsD 29 104 4.1E-11 T 28-03-2018 IPR010712 Arsenical-resistance operon trans-acting repressor ArsD GO:0003677|GO:0045892|GO:0046685 CDW54_RS10530 0a4a4eea16a36c96e1744cc3f23c924c 116 Pfam PF13630 SdpI/YhfL protein family 28 92 2.4E-10 T 28-03-2018 IPR025962 SdpI/YhfL protein family CDW54_RS01705 a200d0f995de004bba68ba493dcf53dc 408 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 82 225 2.9E-47 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CDW54_RS01705 a200d0f995de004bba68ba493dcf53dc 408 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 81 225 4.7E-44 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CDW54_RS06635 c7806f3c6a48745d193f3f64b6a17025 88 Pfam PF06769 YoeB-like toxin of bacterial type II toxin-antitoxin system 22 87 1.1E-9 T 28-03-2018 IPR009614 Toxin YoeB GO:0004519|GO:0006401 CDW54_RS06635 c7806f3c6a48745d193f3f64b6a17025 88 Gene3D G3DSA:3.30.2310.20 1 88 4.3E-20 T 28-03-2018 CDW54_RS06635 c7806f3c6a48745d193f3f64b6a17025 88 TIGRFAM TIGR02116 toxin_Txe_YoeB: addiction module toxin, Txe/YoeB family 9 87 5.3E-25 T 28-03-2018 IPR009614 Toxin YoeB GO:0004519|GO:0006401 CDW54_RS06635 c7806f3c6a48745d193f3f64b6a17025 88 SUPERFAMILY SSF143011 4 88 1.7E-16 T 28-03-2018 IPR035095 Toxin RelE-like domain CDW54_RS12340 d7f9ed3e6574594a2a7fd5cca2042a5f 213 Pfam PF12917 HD containing hydrolase-like enzyme 1 197 4.3E-75 T 28-03-2018 IPR027366 HD containing hydrolase-like enzyme CDW54_RS12340 d7f9ed3e6574594a2a7fd5cca2042a5f 213 SUPERFAMILY SSF109604 4 188 6.6E-32 T 28-03-2018 CDW54_RS12340 d7f9ed3e6574594a2a7fd5cca2042a5f 213 Gene3D G3DSA:1.10.3210.10 1 213 1.6E-39 T 28-03-2018 CDW54_RS04980 87162e2e473d33ad0bddaae0c1a3fe76 274 Gene3D G3DSA:1.10.3470.10 2 266 2.3E-26 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CDW54_RS04980 87162e2e473d33ad0bddaae0c1a3fe76 274 Pfam PF00950 ABC 3 transport family 5 261 3.8E-76 T 28-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 CDW54_RS04980 87162e2e473d33ad0bddaae0c1a3fe76 274 SUPERFAMILY SSF81345 3 258 5.75E-40 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CDW54_RS06850 35bc88327d94943c36e7731eb171480b 400 Pfam PF14281 PD-(D/E)XK nuclease superfamily 30 199 2.7E-34 T 28-03-2018 IPR029470 PD-(D/E)XK nuclease superfamily 4 CDW54_RS09835 edd8e01942992159fe5a5e22ae0710e6 116 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 1 108 8.3E-27 T 28-03-2018 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV CDW54_RS03520 464009420875eb027294417a7814ec6c 619 SUPERFAMILY SSF53649 319 494 5.45E-14 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CDW54_RS03520 464009420875eb027294417a7814ec6c 619 Gene3D G3DSA:3.40.720.10 253 558 1.3E-20 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CDW54_RS03520 464009420875eb027294417a7814ec6c 619 Pfam PF00884 Sulfatase 260 546 8.4E-37 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CDW54_RS11335 c6141093e095f7ad5cd737a1063363d6 257 Pfam PF07556 Protein of unknown function (DUF1538) 25 234 1.1E-62 T 28-03-2018 IPR011435 Protein of unknown function DUF1538 CDW54_RS11440 e2e7b1b6cde9344e6cad4304adba1361 167 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 146 1.8E-62 T 28-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 CDW54_RS11440 e2e7b1b6cde9344e6cad4304adba1361 167 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 153 85.791 T 28-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 CDW54_RS11440 e2e7b1b6cde9344e6cad4304adba1361 167 Pfam PF03477 ATP cone domain 50 136 8.7E-19 T 28-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 CDW54_RS10280 0b38d2b017830504ff55eacf63e4adc3 313 Pfam PF01882 Protein of unknown function DUF58 143 182 2.1E-11 T 28-03-2018 IPR002881 Domain of unknown function DUF58 CDW54_RS07990 907bc4e85feff8d6883d2c4b1115564a 225 SUPERFAMILY SSF52218 1 220 2.14E-39 T 28-03-2018 IPR029039 Flavoprotein-like domain CDW54_RS07990 907bc4e85feff8d6883d2c4b1115564a 225 Pfam PF02525 Flavodoxin-like fold 1 160 2.6E-31 T 28-03-2018 IPR003680 Flavodoxin-like fold CDW54_RS07990 907bc4e85feff8d6883d2c4b1115564a 225 Gene3D G3DSA:3.40.50.360 1 212 2.4E-29 T 28-03-2018 IPR029039 Flavoprotein-like domain CDW54_RS08260 21a51f454b1eccd393365352a8be1b04 125 Pfam PF06279 Protein of unknown function (DUF1033) 1 117 8.5E-52 T 28-03-2018 IPR010434 Protein of unknown function DUF1033 CDW54_RS07780 fd3ae30631899e0fa86f18d5f5536e11 393 Pfam PF01594 AI-2E family transporter 32 361 7.4E-66 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like CDW54_RS08875 6ef14f7286722b07ce6bebcdbee5c0a8 226 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 41 225 2.5E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS08875 6ef14f7286722b07ce6bebcdbee5c0a8 226 Gene3D G3DSA:1.10.3720.10 15 226 4.4E-28 T 28-03-2018 CDW54_RS08875 6ef14f7286722b07ce6bebcdbee5c0a8 226 SUPERFAMILY SSF161098 17 212 3.66E-38 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS06710 a2455ec74220ce503d37c560c065d904 159 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 20 148 8.8E-33 T 28-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component CDW54_RS07690 fc2981020ac1566b78489aacdd39b423 162 Pfam PF17295 Domain of unknown function (DUF5348) 78 158 5.0E-18 T 28-03-2018 IPR035255 Domain of unknown function DUF5348 CDW54_RS07530 0af084256883bea9ba6d13beb13eef96 473 Pfam PF13520 Amino acid permease 12 431 3.3E-48 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CDW54_RS07530 0af084256883bea9ba6d13beb13eef96 473 PIRSF PIRSF006060 4 472 7.2E-54 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CDW54_RS03575 7c68a262b2c94eac70f6ab6abb192dc7 287 SUPERFAMILY SSF161098 21 286 6.93E-74 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS03575 7c68a262b2c94eac70f6ab6abb192dc7 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 279 9.9E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS03575 7c68a262b2c94eac70f6ab6abb192dc7 287 Gene3D G3DSA:1.10.3720.10 9 274 2.3E-43 T 28-03-2018 CDW54_RS03135 0418c399e9e07c55cb6764b188b68b4c 178 TIGRFAM TIGR04518 ECF_S_folT_fam: ECF transporter S component, folate family 6 163 4.4E-40 T 28-03-2018 IPR030949 ECF transporter S component, folate family CDW54_RS03135 0418c399e9e07c55cb6764b188b68b4c 178 Pfam PF12822 ECF transporter, substrate-specific component 9 160 1.1E-11 T 28-03-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 CDW54_RS01200 cde39c4cdcd87d1d2b7d5016f58bfa64 494 Pfam PF03611 PTS system sugar-specific permease component 15 434 4.6E-123 T 28-03-2018 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 CDW54_RS07685 f1d6b7e79cabcab894de339fc23253c4 263 Pfam PF13349 Putative adhesin 42 258 5.1E-12 T 28-03-2018 IPR025164 Putative adhesin CDW54_RS11800 73247dad96c4f3a95c32ebbe91e38c1e 80 Pfam PF04226 Transglycosylase associated protein 33 78 4.7E-11 T 28-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 CDW54_RS07000 1d086b53ec9325ce70deccdef025b1eb 186 Pfam PF14278 Transcriptional regulator C-terminal region 84 160 2.7E-14 T 28-03-2018 CDW54_RS07000 1d086b53ec9325ce70deccdef025b1eb 186 Gene3D G3DSA:1.10.357.10 2 161 1.1E-13 T 28-03-2018 CDW54_RS07000 1d086b53ec9325ce70deccdef025b1eb 186 SUPERFAMILY SSF46689 5 72 8.21E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDW54_RS08410 6281f32c1161feafd0b0851073f28b12 126 Gene3D G3DSA:3.40.1800.10 47 125 1.5E-6 T 28-03-2018 CDW54_RS08410 6281f32c1161feafd0b0851073f28b12 126 Pfam PF01844 HNH endonuclease 68 116 5.4E-7 T 28-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 CDW54_RS06655 0dda34291573c3a8deb8d7b8573338b0 213 Gene3D G3DSA:1.10.3720.10 1 206 9.0E-30 T 28-03-2018 CDW54_RS06655 0dda34291573c3a8deb8d7b8573338b0 213 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 203 3.9E-25 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS06655 0dda34291573c3a8deb8d7b8573338b0 213 SUPERFAMILY SSF161098 12 195 1.24E-40 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS09175 7a5e80b297a3f430291fa5c3af2edaa5 268 Gene3D G3DSA:1.10.3720.10 6 260 1.5E-33 T 28-03-2018 CDW54_RS09175 7a5e80b297a3f430291fa5c3af2edaa5 268 SUPERFAMILY SSF161098 2 258 1.96E-48 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS03400 bb13fc2ccc31b496dcc585f770e9444d 466 Pfam PF02386 Cation transport protein 53 447 3.3E-61 T 28-03-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 CDW54_RS10635 8af74b4eab095c106cd38b517cedbb30 443 Pfam PF07613 Protein of unknown function (DUF1576) 259 421 3.7E-51 T 28-03-2018 IPR011470 Protein of unknown function DUF1576 CDW54_RS10635 8af74b4eab095c106cd38b517cedbb30 443 Pfam PF07613 Protein of unknown function (DUF1576) 44 218 9.0E-57 T 28-03-2018 IPR011470 Protein of unknown function DUF1576 CDW54_RS09590 42b84f25a74c099f90ff05394a81cc99 191 Pfam PF12822 ECF transporter, substrate-specific component 10 175 2.4E-8 T 28-03-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 CDW54_RS02240 00eb8629cd790cdddfddc42cd6a7d041 614 Gene3D G3DSA:3.30.565.10 401 597 5.1E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDW54_RS03665 57503d4eea12b5134e48c9973650b20a 289 Pfam PF09648 YycH protein 31 273 5.3E-58 T 28-03-2018 IPR018604 Regulatory protein YycH-like GO:0016021 CDW54_RS07490 d13a5b9d32964d5b99855588f7a6c8d3 221 Pfam PF10786 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) 3 215 1.5E-93 T 28-03-2018 IPR019722 Glucose-6-phosphate 1-dehydrogenase, bacterial CDW54_RS00485 0b58a0baf9cca19c355784bd64041716 227 SUPERFAMILY SSF51412 61 204 9.06E-13 T 28-03-2018 CDW54_RS00485 0b58a0baf9cca19c355784bd64041716 227 Gene3D G3DSA:3.20.20.70 93 203 2.5E-16 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDW54_RS03065 3cfe4db25d03020279d20fa18d6f33e5 125 Gene3D G3DSA:1.20.1070.10 16 112 9.8E-4 T 28-03-2018 CDW54_RS01395 ed30250dbcf812ad231ba4a68351b3ad 189 Pfam PF02620 Uncharacterized ACR, COG1399 57 178 3.4E-25 T 28-03-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD CDW54_RS00960 622e25df916862ea8de9aac5954813a2 507 Pfam PF03606 C4-dicarboxylate anaerobic carrier 11 503 2.0E-148 T 28-03-2018 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 CDW54_RS07155 3660f251a22b42668d6716dfe96a5605 121 Pfam PF07784 Protein of unknown function (DUF1622) 31 113 9.0E-25 T 28-03-2018 IPR012427 Protein of unknown function DUF1622 CDW54_RS03645 b539e9d48e8c8629430bc0bfe361e6b5 220 Pfam PF02517 CAAX protease self-immunity 123 206 2.2E-15 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CDW54_RS03570 ffd87d9ba96b556ec6d451495020e8e1 187 Pfam PF04854 Protein of unknown function, DUF624 19 85 5.7E-10 T 28-03-2018 IPR006938 Protein of unknown function DUF624 CDW54_RS01700 16d24c898f01d8a655269c1c3e3aee0b 156 PIRSF PIRSF005859 1 156 1.4E-44 T 28-03-2018 IPR004307 TspO/MBR-related protein GO:0016021 CDW54_RS01700 16d24c898f01d8a655269c1c3e3aee0b 156 Pfam PF03073 TspO/MBR family 13 153 3.2E-40 T 28-03-2018 IPR004307 TspO/MBR-related protein GO:0016021 CDW54_RS06970 570d3dd22d3f9916f0d160d9cbcf2c5b 82 Pfam PF04226 Transglycosylase associated protein 33 77 2.2E-11 T 28-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 CDW54_RS04355 b65b9c3403009d0cdba5411daa6b456e 499 SMART SM00858 15 86 8.5E-17 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CDW54_RS04355 b65b9c3403009d0cdba5411daa6b456e 499 Pfam PF08666 SAF domain 15 86 2.9E-13 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CDW54_RS04355 b65b9c3403009d0cdba5411daa6b456e 499 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 111 498 8.1E-158 T 28-03-2018 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 CDW54_RS09310 bf1ff98ae28a7893713794f5fb6fa41e 226 Pfam PF13731 WxL domain surface cell wall-binding 27 224 3.7E-45 T 28-03-2018 IPR027994 WxL domain CDW54_RS10330 e69cc3893155d4b71e84b6c62f81dc1e 105 Pfam PF13630 SdpI/YhfL protein family 26 91 5.9E-8 T 28-03-2018 IPR025962 SdpI/YhfL protein family CDW54_RS09830 99b3b69b0dfefd6d97f160b047dd0918 105 Pfam PF04024 PspC domain 3 61 1.1E-16 T 28-03-2018 IPR007168 Phage shock protein, PspC, N-terminal CDW54_RS05565 972705a4f926d8dfc8f2091113b603b3 63 Pfam PF06107 Bacterial protein of unknown function (DUF951) 2 56 4.3E-31 T 28-03-2018 IPR009296 Protein of unknown function DUF951 CDW54_RS05565 972705a4f926d8dfc8f2091113b603b3 63 PIRSF PIRSF037263 1 62 2.7E-35 T 28-03-2018 IPR009296 Protein of unknown function DUF951 CDW54_RS04325 e36b83cbee082592c8a0abe0e13f19ed 324 Gene3D G3DSA:1.10.3720.10 36 322 2.3E-38 T 28-03-2018 CDW54_RS04325 e36b83cbee082592c8a0abe0e13f19ed 324 SUPERFAMILY SSF161098 80 309 4.45E-47 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS04325 e36b83cbee082592c8a0abe0e13f19ed 324 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 318 3.4E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDW54_RS03285 593eda93a7ec5ccb8a2f41cc18025766 161 Pfam PF04073 Aminoacyl-tRNA editing domain 41 147 1.7E-26 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CDW54_RS03285 593eda93a7ec5ccb8a2f41cc18025766 161 SUPERFAMILY SSF55826 4 159 1.83E-37 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CDW54_RS03285 593eda93a7ec5ccb8a2f41cc18025766 161 Gene3D G3DSA:3.90.960.10 1 158 2.2E-28 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CDW54_RS05040 a218b0dcf14b8c66cb59e741c8a0ac08 428 Pfam PF05193 Peptidase M16 inactive domain 181 363 2.3E-16 T 28-03-2018 IPR007863 Peptidase M16, C-terminal CDW54_RS05040 a218b0dcf14b8c66cb59e741c8a0ac08 428 Pfam PF00675 Insulinase (Peptidase family M16) 63 173 3.2E-15 T 28-03-2018 IPR011765 Peptidase M16, N-terminal CDW54_RS05040 a218b0dcf14b8c66cb59e741c8a0ac08 428 SUPERFAMILY SSF63411 282 420 1.92E-15 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CDW54_RS05040 a218b0dcf14b8c66cb59e741c8a0ac08 428 Gene3D G3DSA:3.30.830.10 222 428 2.4E-16 T 28-03-2018 CDW54_RS05040 a218b0dcf14b8c66cb59e741c8a0ac08 428 Gene3D G3DSA:3.30.830.10 2 221 1.8E-50 T 28-03-2018 CDW54_RS05040 a218b0dcf14b8c66cb59e741c8a0ac08 428 SUPERFAMILY SSF63411 7 234 3.03E-45 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CDW54_RS06960 8043dc90c0d58c683ce1fc54f3bfa59e 130 Gene3D G3DSA:2.10.290.10 3 91 3.8E-4 T 28-03-2018 CDW54_RS10310 e6f7973f0deda79150f4fcbba084db12 137 Pfam PF14015 Protein of unknown function (DUF4231) 25 112 1.6E-10 T 28-03-2018 IPR025325 Protein of unknown function DUF4231 CDW54_RS01800 b0a807c66584ea62498d9a438bfe4e86 460 Pfam PF04932 O-Antigen ligase 211 384 2.4E-16 T 28-03-2018 IPR007016 O-antigen ligase-related CDW54_RS01730 039d3d558568f9c7297dc775a460a2a7 267 Pfam PF06691 Protein of unknown function (DUF1189) 5 254 4.3E-62 T 28-03-2018 IPR009574 Protein of unknown function DUF1189 CDW54_RS06675 4df3c470445c9b5d71bcd037b5c81b06 232 Pfam PF06161 Protein of unknown function (DUF975) 137 229 4.4E-24 T 28-03-2018 IPR010380 Protein of unknown function DUF975 CDW54_RS06675 4df3c470445c9b5d71bcd037b5c81b06 232 Pfam PF06161 Protein of unknown function (DUF975) 1 144 9.1E-14 T 28-03-2018 IPR010380 Protein of unknown function DUF975 CDW54_RS08625 1bf075248eadfe60cae908c53120b8ba 449 Pfam PF08708 Primase C terminal 1 (PriCT-1) 212 276 8.2E-17 T 28-03-2018 IPR014820 Primase, C-terminal 1 CDW54_RS09405 b2b04188998b8e633c00f9af97627e56 420 Gene3D G3DSA:3.40.190.10 44 151 1.9E-17 T 28-03-2018 CDW54_RS09405 b2b04188998b8e633c00f9af97627e56 420 Pfam PF12698 ABC-2 family transporter protein 20 384 7.7E-49 T 28-03-2018 CDW54_RS12410 b9820e4889ad76a9a1a9c1c9e3db5994 232 Gene3D G3DSA:3.10.580.10 98 232 3.5E-12 T 28-03-2018 CDW54_RS12410 b9820e4889ad76a9a1a9c1c9e3db5994 232 Pfam PF00571 CBS domain 177 228 0.0022 T 28-03-2018 IPR000644 CBS domain CDW54_RS12410 b9820e4889ad76a9a1a9c1c9e3db5994 232 SUPERFAMILY SSF54631 103 230 8.17E-12 T 28-03-2018 CDW54_RS02285 2ef0ae3e3005f093998484e0f489daa8 49 Pfam PF12459 D-Ala-teichoic acid biosynthesis protein 10 49 1.6E-19 T 28-03-2018 IPR021008 Protein of unknown function DUF3687 CDW54_RS07235 fbebe3d80d8f6fff5c24bdc2ab7344b1 358 Pfam PF01757 Acyltransferase family 41 345 2.6E-12 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CDW54_RS10290 ae4ca8fe77c5c94f2e27ceb226ad9834 270 Gene3D G3DSA:1.10.10.10 5 74 3.1E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS00825 0cf45f1d7dbceb0192eca52d7cb0bf1f 237 Pfam PF09911 Uncharacterized protein conserved in bacteria (DUF2140) 16 202 5.1E-68 T 28-03-2018 IPR018672 Protein of unknown function DUF2140 CDW54_RS00550 61688b3965e255a57439c492bab04195 352 Pfam PF03547 Membrane transport protein 16 161 5.2E-19 T 28-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 CDW54_RS10295 db2d1df37455b2075d553c1667ab5404 189 SUPERFAMILY SSF143120 10 64 8.37E-6 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CDW54_RS09295 0d6c8072dcfd28048a90fbd6b73b848d 156 Pfam PF16067 Domain of unknown function (DUF4809) 1 129 3.7E-51 T 28-03-2018 IPR032080 Protein of unknown function DUF4809 CDW54_RS06815 4f00875f763315327ac60f084c4814e5 116 Pfam PF03413 Peptidase propeptide and YPEB domain 39 107 7.7E-6 T 28-03-2018 IPR025711 PepSY domain CDW54_RS06310 db12ee9a580bb43e136722885abaf2a6 73 Pfam PF11195 Protein of unknown function (DUF2829) 2 72 3.9E-26 T 28-03-2018 IPR021361 Protein of unknown function DUF2829 CDW54_RS12145 85045c3d1837b71ec4887ec4a05cc36f 161 Pfam PF07155 ECF-type riboflavin transporter, S component 2 153 1.1E-40 T 28-03-2018 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 CDW54_RS03315 599a61ba48df070515b1ebd49dc9b167 212 Pfam PF02517 CAAX protease self-immunity 110 202 2.2E-6 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CDW54_RS02105 22f830e0a153a84770952ca95b461eb1 38 Pfam PF13253 Protein of unknown function (DUF4044) 3 35 4.5E-15 T 28-03-2018 IPR025270 Protein of unknown function DUF4044 CDW54_RS05445 4fd8c36881e265ac9007ff852231f900 307 Pfam PF01136 Peptidase family U32 72 303 3.0E-47 T 28-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 CDW54_RS05445 4fd8c36881e265ac9007ff852231f900 307 Gene3D G3DSA:3.20.20.70 4 280 2.6E-5 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDW54_RS06300 601947cf318afac0ec3484db028888a1 233 Pfam PF04172 LrgB-like family 15 226 2.5E-73 T 28-03-2018 IPR007300 CidB/LrgB family CDW54_RS00520 5ec23d6196750de2fd977ae669603b26 200 Pfam PF06081 Aromatic acid exporter family member 1 7 155 6.0E-11 T 28-03-2018 IPR010343 Aromatic acid exporter family member 1 CDW54_RS11625 44e45ef82bfb6c23b5dc0200da8877df 71 Pfam PF04070 Domain of unknown function (DUF378) 2 60 9.6E-25 T 28-03-2018 IPR007211 Protein of unknown function DUF378 CDW54_RS02255 7250690bfdf6b2dc4d8009952061fca2 267 Pfam PF06161 Protein of unknown function (DUF975) 7 255 1.7E-18 T 28-03-2018 IPR010380 Protein of unknown function DUF975 CDW54_RS02095 2aeb2e5a429f8b405c806f2cfe1fd0dd 122 Pfam PF11877 Protein of unknown function (DUF3397) 8 118 3.0E-33 T 28-03-2018 IPR024515 Protein of unknown function DUF3397 CDW54_RS04095 cf7a54e786520b2301d7609faa6dfe28 162 Pfam PF11217 Protein of unknown function (DUF3013) 1 161 3.7E-65 T 28-03-2018 IPR021380 Protein of unknown function DUF3013 CDW54_RS00655 13581d8c16bb3dfa6149d421391762f6 222 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 10 190 1.2E-45 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT CDW54_RS10155 30cdddd67fb12f473b2b299c515f0b93 215 Pfam PF16571 FBP C-terminal treble-clef zinc-finger 100 201 1.6E-9 T 28-03-2018 IPR032330 Elongation factor G-binding protein, C-terminal treble-clef zinc-finger CDW54_RS10155 30cdddd67fb12f473b2b299c515f0b93 215 Pfam PF07299 Elongation factor G-binding protein, N-terminal 4 86 5.2E-30 T 28-03-2018 IPR010841 Elongation factor G-binding protein, N-terminal CDW54_RS01085 7aa1e2bae2040c1823ad9a5d6f3020d2 250 Pfam PF13649 Methyltransferase domain 45 128 4.2E-9 T 28-03-2018 CDW54_RS01085 7aa1e2bae2040c1823ad9a5d6f3020d2 250 SUPERFAMILY SSF53335 4 189 3.0E-16 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDW54_RS01085 7aa1e2bae2040c1823ad9a5d6f3020d2 250 Gene3D G3DSA:3.40.50.150 2 235 3.4E-16 T 28-03-2018 CDW54_RS05620 04b7dd16e2fb2c7e37ec320d69a63022 85 Gene3D G3DSA:1.10.10.10 35 85 2.5E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDW54_RS09145 4228a8a47e62e8c31e1081687dc982ed 210 Pfam PF12822 ECF transporter, substrate-specific component 5 194 1.2E-31 T 28-03-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 CDW54_RS10725 49ea4c5953c2f91367f4efab0b87e9e2 121 Pfam PF04343 Protein of unknown function, DUF488 3 114 1.6E-29 T 28-03-2018 IPR007438 Protein of unknown function DUF488 CDW54_RS02930 e84d047b41b08c8e7428d915c2bd312d 219 TIGRFAM TIGR01906 integ_TIGR01906: integral membrane protein TIGR01906 13 211 8.6E-56 T 28-03-2018 IPR010178 Integral membrane protein 1906 CDW54_RS02930 e84d047b41b08c8e7428d915c2bd312d 219 Pfam PF07314 Protein of unknown function (DUF1461) 14 184 1.6E-50 T 28-03-2018 IPR010178 Integral membrane protein 1906 CDW54_RS02330 47f2286679ac9d0f1906ab4addca5b08 274 Pfam PF04468 PSP1 C-terminal conserved region 62 146 1.9E-28 T 28-03-2018 IPR007557 PSP1, C-terminal CDW54_RS02370 32e4baa74e5b1872215bdc005018aec4 394 Gene3D G3DSA:3.90.820.10 4 68 1.9E-13 T 28-03-2018 CDW54_RS02370 32e4baa74e5b1872215bdc005018aec4 394 Gene3D G3DSA:3.90.820.10 105 162 7.4E-7 T 28-03-2018 CDW54_RS07150 b20ced63f28fa92ad03a9b96e3ea4cd3 121 Pfam PF07784 Protein of unknown function (DUF1622) 30 109 5.3E-25 T 28-03-2018 IPR012427 Protein of unknown function DUF1622 CDW54_RS02220 949b09d98252b2774d30c7b64b186128 119 Pfam PF06993 Protein of unknown function (DUF1304) 11 117 6.2E-32 T 28-03-2018 IPR009732 Protein of unknown function DUF1304 CDW54_RS06615 58dc6635aaac68600470ac4276a3cd2e 607 Pfam PF13520 Amino acid permease 26 443 2.8E-35 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CDW54_RS00530 9a330caffeb86cd77c47da830ecba9d9 174 Gene3D G3DSA:2.40.50.140 86 171 1.7E-16 T 28-03-2018 CDW54_RS09240 df43730bb2c9fb79786dedb16a2d41c2 159 Pfam PF12821 Threonine/Serine exporter, ThrE 7 134 2.5E-44 T 28-03-2018 IPR024528 Threonine/Serine exporter, ThrE