locus-tag	class	description
HZ311_RS00015	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
HZ311_RS00055	ENOG4105CK1	PTS System
HZ311_RS00060	ENOG4105CQ4	Transcriptional regulator
HZ311_RS00065	ENOG4105D9R	oxidoreductase
HZ311_RS00070	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HZ311_RS00075	ENOG4105CVJ	phosphoglycerate mutase
HZ311_RS00110	ENOG4108STX	response regulator
HZ311_RS00115	ENOG4105US7	Histidine kinase
HZ311_RS00120	ENOG4108XZ3	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division (By similarity)
HZ311_RS00130	ENOG4105DWF	phosphomethylpyrimidine kinase
HZ311_RS00135	ENOG4105PUK	Membrane
HZ311_RS00140	ENOG4108UIC	UPF0340 protein
HZ311_RS00160	ENOG4105EPR	degv family
HZ311_RS00210	ENOG4105D9N	nucleoside
HZ311_RS00240	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
HZ311_RS00250	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HZ311_RS00260	ENOG4105EG2	ABC transporter, permease
HZ311_RS00265	ENOG4105D56	permease protein
HZ311_RS00270	ENOG4107FKK	extracellular solute-binding protein family 1
HZ311_RS00275	ENOG4108IUK	alpha amylase, catalytic
HZ311_RS00280	ENOG4105DTQ	mandelate racemase muconate lactonizing
HZ311_RS00290	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
HZ311_RS00295	ENOG4105E4F	Isochorismate synthase
HZ311_RS00300	ENOG4105CEY	Amp-dependent synthetase and ligase
HZ311_RS00305	ENOG4108IPT	Naphthoate synthase
HZ311_RS00370	ENOG4105K56	Transcriptional regulator
HZ311_RS00375	ENOG4107QHE	Choloylglycine hydrolase
HZ311_RS00410	ENOG4107RVG	penicillin-binding protein
HZ311_RS00415	ENOG4108RCF	TRANSCRIPTIONal
HZ311_RS00420	ENOG4107XC4	flavin reductase domain protein, FMN-binding
HZ311_RS00435	ENOG4105CGH	5'-nucleotidase
HZ311_RS00440	ENOG4108IJG	ABC transporter substrate-binding protein
HZ311_RS00470	ENOG4107BMA	Transglycosylase associated protein
HZ311_RS00495	ENOG410695V	Essential for the production of a quorum sensing system signal molecule, the autoinducing peptide (AIP). This quorum sensing system is responsible for the regulation of the expression of virulence factor genes. Involved in the proteolytic processing of AgrD, the precursor of AIP (By similarity)
HZ311_RS00515	ENOG4105VMP	Transcriptional regulator
HZ311_RS00545	ENOG4107BMA	Transglycosylase associated protein
HZ311_RS00565	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HZ311_RS00580	ENOG4105X1N	Glycosyl transferase family 8
HZ311_RS00585	ENOG4105X1N	Glycosyl transferase family 8
HZ311_RS00600	ENOG4105TIV	Cryptic phage CTXphi transcriptional repressor RstR
HZ311_RS00610	ENOG4105VEQ	Cold shock protein
HZ311_RS00635	ENOG4108Z6Z	Transcriptional regulator
HZ311_RS00650	ENOG41086FC	50S ribosomal protein l32
HZ311_RS00655	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HZ311_RS00670	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HZ311_RS00680	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
HZ311_RS00705	ENOG4105C8I	hydrolase, family 38
HZ311_RS00710	ENOG4105DM4	PTS System
HZ311_RS00715	ENOG4108YRF	PTS System
HZ311_RS00720	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
HZ311_RS00725	ENOG4105EMD	TRANSCRIPTIONal
HZ311_RS00730	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HZ311_RS00740	ENOG4105CK1	PTS System
HZ311_RS00745	ENOG4105VZJ	PTS System
HZ311_RS00755	ENOG4107QSE	Dipeptidase
HZ311_RS00760	ENOG4105FDP	GntR family transcriptional regulator
HZ311_RS00775	ENOG4109050	May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG)
HZ311_RS00780	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
HZ311_RS00785	ENOG4105EGD	dinuclear metal center protein, YbgI family
HZ311_RS00810	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
HZ311_RS00820	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
HZ311_RS00825	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
HZ311_RS00830	ENOG4105C2M	dna polymerase I
HZ311_RS00835	ENOG4105HFZ	Membrane
HZ311_RS00845	ENOG4105DFU	Cell wall formation (By similarity)
HZ311_RS00850	ENOG4107DB1	DUF218 domain
HZ311_RS00855	ENOG410906U	SprT-like
HZ311_RS00865	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
HZ311_RS00870	ENOG4105C72	UPF0176 protein
HZ311_RS00910	ENOG4108IBT	Inherit from COG: transposase
HZ311_RS00925	ENOG4107R6U	sodium dicarboxylate symporter
HZ311_RS00990	ENOG4105EQD	regulatoR
HZ311_RS00995	ENOG4105C2F	Histidine kinase
HZ311_RS01000	ENOG4105IKJ	beta-galactosidase small subunit
HZ311_RS01005	ENOG4105CNT	hydrolase family 2
HZ311_RS01010	ENOG4105DME	alpha-galactosidase
HZ311_RS01035	ENOG4105BZ1	(ABC) transporter
HZ311_RS01060	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
HZ311_RS01065	ENOG4105CBD	Diacylglycerol kinase
HZ311_RS01070	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HZ311_RS01075	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HZ311_RS01080	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HZ311_RS01085	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HZ311_RS01090	ENOG4105C4R	Atp-dependent dna helicase
HZ311_RS01095	ENOG4105DM4	PTS System
HZ311_RS01100	ENOG4105DE4	1-phosphofructokinase
HZ311_RS01105	ENOG4105E98	transcriptional regulator DeoR family
HZ311_RS01120	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
HZ311_RS01125	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HZ311_RS01130	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
HZ311_RS01140	ENOG4105VK3	rdd domain containing protein
HZ311_RS01155	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HZ311_RS01230	ENOG4105CIE	May be required for sporulation (By similarity)
HZ311_RS01235	ENOG4105CHW	UPF0052 protein
HZ311_RS01240	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
HZ311_RS01245	ENOG4105CG9	aspartate racemase
HZ311_RS01255	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HZ311_RS01260	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HZ311_RS01265	ENOG4107R0W	ABC transporter
HZ311_RS01280	ENOG4105CK1	PTS System
HZ311_RS01285	ENOG4105VCP	PTS System
HZ311_RS01290	ENOG4105CS2	ec 3.2.1.21
HZ311_RS01295	ENOG4105E98	transcriptional regulator DeoR family
HZ311_RS01300	ENOG4107VXZ	Hydrolase
HZ311_RS01305	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HZ311_RS01310	ENOG4105CFG	Acts as a chaperone (By similarity)
HZ311_RS01315	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HZ311_RS01320	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
HZ311_RS01325	ENOG4105CSA	Coproporphyrinogen iii oxidase
HZ311_RS01410	ENOG4106128	DNA-binding helix-turn-helix protein
HZ311_RS01470	ENOG4108IMY	Transcriptional regulator
HZ311_RS01505	ENOG4105DQ6	Transposase
HZ311_RS01535	ENOG4105D6A	Electron transport complex
HZ311_RS01540	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
HZ311_RS01545	ENOG4105CTQ	phosphohexokinase
HZ311_RS01555	ENOG41090XM	Early upstream open reading frame
HZ311_RS01560	ENOG4105CSC	Glucose uptake protein
HZ311_RS01565	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
HZ311_RS01570	ENOG4105DTN	riboflavin biosynthesis protein ribF
HZ311_RS01575	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HZ311_RS01580	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
HZ311_RS01595	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
HZ311_RS01600	ENOG4105CHV	Transcription elongation factor NusA
HZ311_RS01605	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
HZ311_RS01610	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
HZ311_RS01615	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
HZ311_RS01620	ENOG4105DZP	Membrane-associated zinc metalloprotease
HZ311_RS01625	ENOG4105KNE	Phosphatidate cytidylyltransferase
HZ311_RS01630	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HZ311_RS01635	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
HZ311_RS01640	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
HZ311_RS01645	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
HZ311_RS01650	ENOG4105CE9	30S ribosomal protein S2
HZ311_RS01655	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
HZ311_RS01690	ENOG4105C75	arginyL-tRNA synthetase
HZ311_RS01695	ENOG4105C5B	carbamate kinase
HZ311_RS01700	ENOG4105DBV	ornithine carbamoyltransferase
HZ311_RS01705	ENOG4105CEU	Arginine dihydrolase
HZ311_RS01720	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HZ311_RS01735	ENOG4108PQP	glycosyl transferase group 1
HZ311_RS01740	ENOG4105D3Q	Sugar transferase
HZ311_RS01745	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HZ311_RS01765	ENOG4107YJ4	chain length determinant protein
HZ311_RS01770	ENOG4105HTX	biosynthesis protein
HZ311_RS01790	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HZ311_RS01805	ENOG41072GX	Peptidase M22 Glycoprotease
HZ311_RS01810	ENOG4105CQ4	Transcriptional regulator
HZ311_RS01815	ENOG4105CKN	UDP-glucose-hexose-1-phosphate uridylyltransferase
HZ311_RS01820	ENOG4105CMR	udp-glucose 4-epimerase
HZ311_RS01835	ENOG4105WZW	rhodanese family
HZ311_RS01840	ENOG4105DKQ	ROK family
HZ311_RS01855	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
HZ311_RS01865	ENOG4108IBT	Inherit from COG: transposase
HZ311_RS01880	ENOG4105EHG	Permease protein
HZ311_RS01885	ENOG4105DQ5	transport system permease protein
HZ311_RS01890	ENOG4105E0A	ABC, transporter
HZ311_RS01900	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
HZ311_RS01905	ENOG4105C08	Histidine kinase
HZ311_RS01910	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
HZ311_RS01915	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
HZ311_RS01920	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
HZ311_RS01930	ENOG4105WDJ	50S ribosomal protein L33
HZ311_RS01935	ENOG4105NRR	Uncharacterized protein conserved in bacteria (DUF2188)
HZ311_RS01940	ENOG4105CAQ	asparagine synthetase
HZ311_RS01955	ENOG4107Z3H	Transcriptional regulator, TetR family
HZ311_RS01975	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
HZ311_RS02005	ENOG4105VEQ	Cold shock protein
HZ311_RS02020	ENOG4105VEQ	Cold shock protein
HZ311_RS02030	ENOG4107QYV	phosphohexose isomerase
HZ311_RS02035	ENOG4105D82	Glutamate dehydrogenase
HZ311_RS02040	ENOG4105CBX	hi0933 family
HZ311_RS02045	ENOG4108Z66	YbaK ebsC protein
HZ311_RS02055	ENOG4105DR4	Methyltransferase
HZ311_RS02075	ENOG4105BZU	Histidine kinase
HZ311_RS02080	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HZ311_RS02095	ENOG4107QSA	Oxaloacetate decarboxylase
HZ311_RS02115	ENOG4105XGS	Covalent carrier of the coenzyme of citrate lyase (By similarity)
HZ311_RS02120	ENOG4105DUA	(citrate (pro-3S)-lyase ligase
HZ311_RS02125	ENOG4105D9Q	decarboxylase (Beta subunit)
HZ311_RS02130	ENOG4105PV1	biotin lipoyl attachment domaiN-containing protein
HZ311_RS02140	ENOG4105D4T	Citrate transporter
HZ311_RS02145	ENOG4105FDP	GntR family transcriptional regulator
HZ311_RS02150	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
HZ311_RS02155	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
HZ311_RS02165	ENOG41067V3	Antibiotic biosynthesis monooxygenase
HZ311_RS02170	ENOG4108TVJ	Nitroreductase
HZ311_RS02175	ENOG4105FS7	Transcriptional regulator
HZ311_RS02190	ENOG4107FQX	Alpha-acetolactate decarboxylase
HZ311_RS02235	ENOG4107TCE	N-acetyltransferase
HZ311_RS02245	ENOG4105WDJ	50S ribosomal protein L33
HZ311_RS02250	ENOG41069UX	Beta-N-acetyl-hexosaminidase
HZ311_RS02260	ENOG4105E98	transcriptional regulator DeoR family
HZ311_RS02265	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
HZ311_RS02270	ENOG4107STF	Involved in phosphonate degradation (By similarity)
HZ311_RS02285	ENOG4105E0C	molybdate abc transporter
HZ311_RS02295	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
HZ311_RS02365	ENOG4107QRI	Phosphoketolase
HZ311_RS02370	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
HZ311_RS02385	ENOG4105CMD	Transcriptional regulator, GntR family
HZ311_RS02395	ENOG4108HWW	ABC transporter
HZ311_RS02405	ENOG4105DFW	ABC transporter
HZ311_RS02410	ENOG4107R5U	Periplasmic binding protein LacI transcriptional regulator
HZ311_RS02415	ENOG4105C2F	Histidine kinase
HZ311_RS02420	ENOG4105EQD	regulatoR
HZ311_RS02455	ENOG4105VI0	Pts system, glucitol sorbitol-specific
HZ311_RS02460	ENOG4105DZY	Pts system, glucitol sorbitol-specific
HZ311_RS02465	ENOG410787A	Pts system, glucitol sorbitol-specific
HZ311_RS02480	ENOG4105CHR	reductase
HZ311_RS02495	ENOG4105DWF	phosphomethylpyrimidine kinase
HZ311_RS02500	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
HZ311_RS02510	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
HZ311_RS02515	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
HZ311_RS02520	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
HZ311_RS02530	ENOG4105VB6	UPF0109 protein
HZ311_RS02535	ENOG4105K5M	30s ribosomal protein S16
HZ311_RS02540	ENOG4108YYH	Nadph-dependent fmn reductase
HZ311_RS02545	ENOG4105NAE	bifunctional deaminase-reductase domain protein
HZ311_RS02550	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HZ311_RS02555	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HZ311_RS02560	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
HZ311_RS02565	ENOG4105EWC	Purine nucleoside phosphorylase
HZ311_RS02570	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
HZ311_RS02575	ENOG4105BZU	Histidine kinase
HZ311_RS02580	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
HZ311_RS02585	ENOG4105CVA	phosphate
HZ311_RS02635	ENOG4105E5D	amino acid
HZ311_RS02640	ENOG4105C59	p-type ATPase
HZ311_RS02670	ENOG4105C5S	asparaginyl-tRNA synthetase
HZ311_RS02675	ENOG4105CHM	Aminotransferase
HZ311_RS02685	ENOG4105DVT	helicase
HZ311_RS02690	ENOG4105VEQ	Cold shock protein
HZ311_RS02710	ENOG4107R4J	Chloride channel
HZ311_RS02725	ENOG4108RWN	rrna methyltransferase
HZ311_RS02730	ENOG410855V	Acylphosphatase
HZ311_RS02735	ENOG4107XQC	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity)
HZ311_RS02740	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
HZ311_RS02745	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
HZ311_RS02750	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
HZ311_RS02755	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
HZ311_RS02760	ENOG4107YR5	Diacylglycerol kinase
HZ311_RS02765	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
HZ311_RS02775	ENOG4105C9A	Phoh family
HZ311_RS02780	ENOG4105KTH	gatB Yqey
HZ311_RS02785	ENOG4105VCC	30S ribosomal protein S21
HZ311_RS02790	ENOG4105N80	Ferric uptake regulator, Fur family
HZ311_RS02795	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
HZ311_RS02800	ENOG41066UM	arsR family transcriptional regulator
HZ311_RS02810	ENOG4105C3M	thioredoxin reductase
HZ311_RS02815	ENOG4105CS2	ec 3.2.1.21
HZ311_RS02820	ENOG4105F8D	glycoside hydrolase family 4
HZ311_RS02825	ENOG4108Q3X	Transcriptional regulator
HZ311_RS02830	ENOG4105C5Y	PTS System
HZ311_RS02835	ENOG4105CID	antiterminator
HZ311_RS02840	ENOG4105BZ1	(ABC) transporter
HZ311_RS02845	ENOG4105BZ1	(ABC) transporter
HZ311_RS02850	ENOG4105VXM	UPF0154 protein
HZ311_RS02855	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
HZ311_RS02865	ENOG4105CV8	reductase
HZ311_RS02870	ENOG4105VUF	Transcriptional regulator
HZ311_RS02880	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
HZ311_RS02890	ENOG4105ETE	Transcriptional regulator (LacI family
HZ311_RS02895	ENOG4105DC7	peptidase M24
HZ311_RS02915	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HZ311_RS02920	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
HZ311_RS02925	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HZ311_RS02930	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
HZ311_RS02960	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
HZ311_RS02965	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HZ311_RS02970	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HZ311_RS02975	ENOG4105E2Z	phosphate ABC transporter (Permease
HZ311_RS02980	ENOG4105C8U	phosphate abc transporter
HZ311_RS02985	ENOG4105CVA	phosphate
HZ311_RS02990	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HZ311_RS02995	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
HZ311_RS03000	ENOG4105CAK	Cell division ATP-binding protein ftsE
HZ311_RS03010	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HZ311_RS03020	ENOG41081UC	Inherit from COG: Competence protein
HZ311_RS03035	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
HZ311_RS03075	ENOG41066F8	ROK family
HZ311_RS03085	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
HZ311_RS03095	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HZ311_RS03155	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HZ311_RS03165	ENOG4105XZU	Preprotein translocase, subunit SecG
HZ311_RS03170	ENOG410830R	acetyltransferase
HZ311_RS03180	ENOG4105DU0	nucleoside hydrolase
HZ311_RS03190	ENOG4108UW5	maltose o-acetyltransferase
HZ311_RS03250	ENOG4105CP7	Triose-phosphate isomerase
HZ311_RS03255	ENOG4105BZA	Phosphoglycerate kinase
HZ311_RS03270	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HZ311_RS03290	ENOG4108Z1Y	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling (By similarity)
HZ311_RS03300	ENOG4105JGI	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity)
HZ311_RS03305	ENOG4105DCI	Phosphohydrolase
HZ311_RS03310	ENOG410667J	hydrolase
HZ311_RS03315	ENOG4105M6F	mutator MutT protein
HZ311_RS03380	ENOG4105DMC	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
HZ311_RS03390	ENOG4108IUX	(ABC) transporter
HZ311_RS03395	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
HZ311_RS03400	ENOG4105K63	Thioredoxin
HZ311_RS03405	ENOG4105C98	muts2 protein
HZ311_RS03420	ENOG4107FSS	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HZ311_RS03425	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HZ311_RS03440	ENOG4105KBX	Transcriptional regulator, TetR family
HZ311_RS03445	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HZ311_RS03455	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
HZ311_RS03495	ENOG4105JAB	phenazine biosynthesis protein, phzf family
HZ311_RS03500	ENOG4105CIF	Ornithine Cyclodeaminase
HZ311_RS03505	ENOG4107U9B	transcriptional regulator
HZ311_RS03510	ENOG4105C6K	Malic enzyme
HZ311_RS03530	ENOG4105VPH	UPF0473 protein
HZ311_RS03535	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
HZ311_RS03540	ENOG4105VBH	UPF0297 protein
HZ311_RS03555	ENOG4108IG5	Transcriptional regulator
HZ311_RS03570	ENOG4108NNR	transporter substrate-binding protein
HZ311_RS03575	ENOG4108PJD	permease
HZ311_RS03590	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
HZ311_RS03595	ENOG4105C5H	ABC transporter
HZ311_RS03600	ENOG4105M10	Involved in the anomeric conversion of L-rhamnose (By similarity)
HZ311_RS03620	ENOG4105CJ1	ABC, transporter
HZ311_RS03625	ENOG4105BZU	Histidine kinase
HZ311_RS03630	ENOG4108VB1	regulatoR
HZ311_RS03670	ENOG4107RUE	extracellular solute-binding protein family 1
HZ311_RS03675	ENOG4105D38	putrescine abc transporter
HZ311_RS03680	ENOG4105F38	ABC transporter, permease
HZ311_RS03685	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HZ311_RS03695	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
HZ311_RS03705	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
HZ311_RS03710	ENOG4105FH5	Membrane
HZ311_RS03725	ENOG4107EFR	Flavocytochrome c
HZ311_RS03740	ENOG4105D4A	Cell wall formation (By similarity)
HZ311_RS03745	ENOG4105EP9	oxidoreductase
HZ311_RS03750	ENOG4105CGK	Exodeoxyribonuclease III
HZ311_RS03755	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
HZ311_RS03765	ENOG4105K8N	protein family UPF0079, ATPase
HZ311_RS03770	ENOG4108IJ2	phosphate acetyltransferase
HZ311_RS03775	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
HZ311_RS03810	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
HZ311_RS03825	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
HZ311_RS03845	ENOG4105D5Q	Arginine ornithine antiporter
HZ311_RS03855	ENOG4105C5Y	PTS System
HZ311_RS03860	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HZ311_RS03915	ENOG4105BZW	Glycerate kinase
HZ311_RS03930	ENOG4105DFD	Na H antiporter
HZ311_RS03940	ENOG4105D01	(LipO)protein
HZ311_RS03945	ENOG4108UMI	ABC transporter, permease
HZ311_RS03950	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HZ311_RS04000	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
HZ311_RS04015	ENOG4105E0M	Sulfatase
HZ311_RS04025	ENOG4105CS2	ec 3.2.1.21
HZ311_RS04040	ENOG4105ZMH	deoxynucleoside kinase
HZ311_RS04070	ENOG41069H0	dihydroorotase EC 3.5.2.3
HZ311_RS04080	ENOG4105CK1	PTS System
HZ311_RS04085	ENOG4105FDP	GntR family transcriptional regulator
HZ311_RS04090	ENOG4105CS2	ec 3.2.1.21
HZ311_RS04095	ENOG4105C5Y	PTS System
HZ311_RS04100	ENOG4105CID	antiterminator
HZ311_RS04105	ENOG4108Z6X	(sortase) family
HZ311_RS04115	ENOG4107RGD	Major Facilitator superfamily
HZ311_RS04120	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
HZ311_RS04125	ENOG4105DB7	PHP domain protein
HZ311_RS04130	ENOG4105S7S	phosphonate abc transporter
HZ311_RS04140	ENOG4105D5T	phosphonate abc transporter
HZ311_RS04150	ENOG4106ZEE	Diacylglycerol kinase
HZ311_RS04155	ENOG4105NDK	ethanolamine utilization protein
HZ311_RS04160	ENOG4105ENY	Ethanolamine utilization protein eutH
HZ311_RS04175	ENOG4108VPX	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity)
HZ311_RS04185	ENOG4105KNY	Microcompartments protein
HZ311_RS04190	ENOG4105C0A	alcohol dehydrogenase
HZ311_RS04200	ENOG4106D67	ethanolamine utilization protein
HZ311_RS04205	ENOG4107FQ9	ethanolamine ammonia-lyase
HZ311_RS04210	ENOG4105CPD	ethanolamine ammonia-lyase
HZ311_RS04215	ENOG4105DYY	Reactivating factor for ethanolamine ammonia lyase
HZ311_RS04230	ENOG4105M3W	utilization protein
HZ311_RS04240	ENOG4108WBT	adenosyltransferase
HZ311_RS04245	ENOG4105KTW	ethanolamine utilization protein
HZ311_RS04255	ENOG4107414	GntR family transcriptional regulator
HZ311_RS04260	ENOG4108S4A	n-acetylmuramoyl-l-alanine amidase
HZ311_RS04280	ENOG4105C4R	Atp-dependent dna helicase
HZ311_RS04295	ENOG4105E0A	ABC, transporter
HZ311_RS04305	ENOG4105EHG	Permease protein
HZ311_RS04310	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
HZ311_RS04320	ENOG4105CS2	ec 3.2.1.21
HZ311_RS04380	ENOG4108M1A	Chitin-binding protein
HZ311_RS04530	ENOG4107YVC	modification (methylase)
HZ311_RS04650	ENOG4105VTR	Integrase
HZ311_RS04655	ENOG4105DIW	FeS assembly protein SUFB
HZ311_RS04660	ENOG4108UNV	SUF system FeS assembly protein, NifU family
HZ311_RS04665	ENOG4105C9B	Cysteine desulfurase
HZ311_RS04670	ENOG4105JRK	feS assembly protein SufD
HZ311_RS04680	ENOG4105D01	(LipO)protein
HZ311_RS04685	ENOG4108UMI	ABC transporter, permease
HZ311_RS04690	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HZ311_RS04695	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
HZ311_RS04720	ENOG4105HMI	Membrane
HZ311_RS04725	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HZ311_RS04730	ENOG4105CKK	Glycosyl transferase, family 2
HZ311_RS04775	ENOG4105CUK	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
HZ311_RS04785	ENOG4105DRS	transport system, permease
HZ311_RS04805	ENOG4105C87	Aminotransferase class I and II
HZ311_RS04810	ENOG4105CI1	PTS System
HZ311_RS04815	ENOG4106KNT	transcriptional regulator
HZ311_RS04820	ENOG4107VKM	6-phosphogluconolactonase
HZ311_RS04830	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
HZ311_RS04835	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HZ311_RS04840	ENOG4108R6K	riboflavin synthase, subunit alpha
HZ311_RS04860	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
HZ311_RS04865	ENOG4105F2M	alpha beta hydrolase fold-3 domain protein
HZ311_RS04870	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HZ311_RS04875	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HZ311_RS04880	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HZ311_RS04885	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
HZ311_RS04890	ENOG4107104	thymidine kinase
HZ311_RS04900	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
HZ311_RS04905	ENOG4105C3F	Signal peptidase i
HZ311_RS04925	ENOG4105DMS	mur ligase
HZ311_RS04930	ENOG4105F1K	Glutamine amidotransferase
HZ311_RS04935	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
HZ311_RS04940	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
HZ311_RS04945	ENOG4105CTS	PTS system mannitol-specific
HZ311_RS04995	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
HZ311_RS05000	ENOG4105ETD	TRANSCRIPTIONal
HZ311_RS05005	ENOG4105CTS	PTS system mannitol-specific
HZ311_RS05010	ENOG4105EV1	Ribose uptake protein RbsU
HZ311_RS05015	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
HZ311_RS05025	ENOG4105DG6	mannose-6-phosphate isomerase
HZ311_RS05050	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
HZ311_RS05060	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
HZ311_RS05075	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
HZ311_RS05095	ENOG4107T7U	Sulfatase
HZ311_RS05100	ENOG4105CUK	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
HZ311_RS05105	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
HZ311_RS05115	ENOG4105DRS	transport system, permease
HZ311_RS05120	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
HZ311_RS05125	ENOG4105BZ7	extracellular solute-binding protein family 1
HZ311_RS05145	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
HZ311_RS05150	ENOG4105DAP	Nicotinate phosphoribosyltransferase
HZ311_RS05160	ENOG4107TXC	Transcriptional regulator
HZ311_RS05175	ENOG4105CK1	PTS System
HZ311_RS05180	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
HZ311_RS05185	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
HZ311_RS05195	ENOG4105Q2H	domain protein
HZ311_RS05210	ENOG4105BZU	Histidine kinase
HZ311_RS05215	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HZ311_RS05230	ENOG4105EPR	degv family
HZ311_RS05245	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
HZ311_RS05250	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HZ311_RS05255	ENOG4105F3R	pts system mannose fructose sorbose family iid
HZ311_RS05260	ENOG4105ETZ	PTS System
HZ311_RS05275	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HZ311_RS05280	ENOG4105C8I	hydrolase, family 38
HZ311_RS05285	ENOG4105DM4	PTS System
HZ311_RS05290	ENOG4108YRF	PTS System
HZ311_RS05305	ENOG410667J	hydrolase
HZ311_RS05315	ENOG4108IJ7	Glycine betaine
HZ311_RS05330	ENOG41067VN	Glutaredoxin
HZ311_RS05335	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HZ311_RS05340	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HZ311_RS05350	ENOG4105DCF	alanine dehydrogenase
HZ311_RS05355	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HZ311_RS05365	ENOG4105C5I	Dehydrogenase
HZ311_RS05405	ENOG4105ETZ	PTS System
HZ311_RS05410	ENOG4105DAS	pts system
HZ311_RS05420	ENOG4105EP8	Glycosyl Hydrolase Family 88
HZ311_RS05430	ENOG4105C02	permease
HZ311_RS05435	ENOG4105KT7	mgtC SapB transporter
HZ311_RS05440	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
HZ311_RS05445	ENOG4105EQ0	Major Facilitator superfamily
HZ311_RS05470	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
HZ311_RS05475	ENOG4108VZM	50s ribosomal protein L10
HZ311_RS05480	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
HZ311_RS05485	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
HZ311_RS05495	ENOG4105EJQ	L-serine dehydratase
HZ311_RS05500	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
HZ311_RS05505	ENOG4105CPN	adenine deaminase
HZ311_RS05515	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HZ311_RS05525	ENOG4105F38	ABC transporter, permease
HZ311_RS05535	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
HZ311_RS05555	ENOG4107FTN	50S ribosomal protein L33
HZ311_RS05575	ENOG4105C7H	Helicase, RecD TraA family
HZ311_RS05590	ENOG4105DHI	Methyltransferase
HZ311_RS05595	ENOG4106N3A	copper homeostasis protein cutc
HZ311_RS05600	ENOG4105CJW	magnesium transporter
HZ311_RS05605	ENOG4105EMS	pseudouridine synthase
HZ311_RS05610	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
HZ311_RS05640	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
HZ311_RS05645	ENOG4108HHA	Transketolase
HZ311_RS05660	ENOG4106ETB	IIa component
HZ311_RS05670	ENOG4105CPQ	Dehydrogenase
HZ311_RS05685	ENOG4108SQ7	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HZ311_RS05690	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
HZ311_RS05710	ENOG4105EYH	Exonuclease
HZ311_RS05715	ENOG4107RFY	SbcCD D subunit
HZ311_RS05720	ENOG4105F6E	Acyl-transferase
HZ311_RS05725	ENOG41060K3	Methyltransferase
HZ311_RS05730	ENOG4105VC4	domain protein
HZ311_RS05735	ENOG4105EXC	Acyl-transferase
HZ311_RS05755	ENOG4107AYK	membrAne
HZ311_RS05760	ENOG4105C9M	aspartyl-trna synthetase
HZ311_RS05765	ENOG4105CUT	histidyl-tRNA synthetase
HZ311_RS05770	ENOG4105CPC	Aldo Keto reductase
HZ311_RS05790	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
HZ311_RS05795	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HZ311_RS05800	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
HZ311_RS05805	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HZ311_RS05815	ENOG4108VX5	3-methyladenine DNA glycosylase
HZ311_RS05820	ENOG4105D1H	recombination factor protein RarA
HZ311_RS05835	ENOG4107YZX	Universal stress protein
HZ311_RS05840	ENOG4105C5Y	PTS System
HZ311_RS05845	ENOG4108HKT	sucrose-6-phosphate hydrolase
HZ311_RS05850	ENOG4105ETE	Transcriptional regulator (LacI family
HZ311_RS05885	ENOG4108VXD	carboxy-peptidase
HZ311_RS05895	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HZ311_RS05925	ENOG4106855	Competence protein
HZ311_RS05945	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
HZ311_RS05965	ENOG4105K59	histidine triad (HIT) protein
HZ311_RS05975	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
HZ311_RS05980	ENOG4105EQI	Metal Dependent Phosphohydrolase
HZ311_RS05985	ENOG4106D4I	domain protein
HZ311_RS06010	ENOG4105DSG	hydrolase family 43
HZ311_RS06025	ENOG4105NTD	Inherit from COG: Hydrolase
HZ311_RS06035	ENOG4105F5H	Glycosyl Hydrolase Family 88
HZ311_RS06055	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
HZ311_RS06060	ENOG41075H3	AraC family transcriptional regulator
HZ311_RS06065	ENOG4107QZW	Altronate oxidoreductase
HZ311_RS06070	ENOG4105CTX	dehydratase
HZ311_RS06075	ENOG4105D2H	Uronic isomerase
HZ311_RS06080	ENOG4107TDE	lipolytic protein G-D-S-L family
HZ311_RS06090	ENOG4105WZB	UPF0342 protein
HZ311_RS06095	ENOG4105BZ4	penicillin-binding protein
HZ311_RS06100	ENOG4108YBP	pseudouridine synthase
HZ311_RS06120	ENOG4105EVU	fructokinase
HZ311_RS06125	ENOG4105C8I	hydrolase, family 38
HZ311_RS06150	ENOG4105EQD	regulatoR
HZ311_RS06155	ENOG4105C2F	Histidine kinase
HZ311_RS06170	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
HZ311_RS06190	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HZ311_RS06195	ENOG4105CK1	PTS System
HZ311_RS06205	ENOG4105VCP	PTS System
HZ311_RS06210	ENOG4105EMD	TRANSCRIPTIONal
HZ311_RS06225	ENOG4105C8T	Leucyl-tRNA synthetase
HZ311_RS06235	ENOG410841Q	phosphoesterase PA-phosphatase related protein
HZ311_RS06240	ENOG4105N5T	Radical SAM Protein
HZ311_RS06255	ENOG4105BZ1	(ABC) transporter
HZ311_RS06260	ENOG4105BZ1	(ABC) transporter
HZ311_RS06265	ENOG4108S4H	thioesterase Superfamily protein
HZ311_RS06275	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HZ311_RS06280	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HZ311_RS06435	ENOG4105CRK	lysyL-tRNA synthetase
HZ311_RS06440	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HZ311_RS06445	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
HZ311_RS06450	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HZ311_RS06455	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
HZ311_RS06460	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HZ311_RS06465	ENOG41060GV	RNA binding s1 domain protein
HZ311_RS06475	ENOG41082I2	s4 domain protein
HZ311_RS06485	ENOG4108JA2	transcriptioN-repair coupling factor
HZ311_RS06490	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
HZ311_RS06495	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
HZ311_RS06525	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
HZ311_RS06535	ENOG4105DJV	ribulose-phosphate 3-epimerase
HZ311_RS06540	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
HZ311_RS06545	ENOG4105D9P	serine threonine protein kinase
HZ311_RS06550	ENOG4108ZF3	Phosphatase
HZ311_RS06555	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HZ311_RS06560	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
HZ311_RS06565	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HZ311_RS06570	ENOG4105C25	Primosomal protein n'
HZ311_RS06575	ENOG4105ZAD	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
HZ311_RS06580	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
HZ311_RS06585	ENOG4105DSJ	YicC domain protein
HZ311_RS06610	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HZ311_RS06615	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HZ311_RS06620	ENOG4105DFT	pur operon repressor
HZ311_RS06630	ENOG4105FDK	ABC transporter
HZ311_RS06635	ENOG4105DSE	periplasmic solute binding protein
HZ311_RS06640	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
HZ311_RS06650	ENOG4105II7	pyrroline-5-carboxylate reductase
HZ311_RS06670	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
HZ311_RS06680	ENOG4105CEV	competence damage-inducible protein
HZ311_RS06685	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
HZ311_RS06705	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
HZ311_RS06710	ENOG4107YB6	acetyltransferase, (GNAT) family
HZ311_RS06715	ENOG4105W42	Veg protein
HZ311_RS06725	ENOG4105M0M	Tetracycline resistance protein
HZ311_RS06735	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HZ311_RS06740	ENOG4105C8N	cysteinyl-tRNA synthetase
HZ311_RS06745	ENOG4105D7W	serine acetyltransferase
HZ311_RS06750	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HZ311_RS06755	ENOG4105CTP	PilT protein domain protein
HZ311_RS06765	ENOG4107Z0P	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
HZ311_RS06770	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
HZ311_RS06775	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
HZ311_RS06785	ENOG41081I9	integral membrane protein
HZ311_RS06790	ENOG4107X35	defense response to bacterium
HZ311_RS06795	ENOG4107X35	defense response to bacterium
HZ311_RS06800	ENOG4105ECR	NmrA family
HZ311_RS06805	ENOG4108Z40	Transcriptional regulator
HZ311_RS06850	ENOG4108MGT	Required for secretion of EsxA and EsxB
HZ311_RS06870	ENOG410646G	Proteins of 100 residues with WXG
HZ311_RS06880	ENOG4105FE1	phytoene synthase
HZ311_RS06895	ENOG4105E3A	(ABC) transporter
HZ311_RS06900	ENOG4105DA5	(ABC) transporter
HZ311_RS06905	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
HZ311_RS06915	ENOG4105CMG	Carbohydrate kinase
HZ311_RS06925	ENOG4105CNN	ABC, transporter
HZ311_RS06930	ENOG4105C2J	ABC transporter
HZ311_RS06935	ENOG4105DSG	hydrolase family 43
HZ311_RS06940	ENOG4105C93	Xylose Isomerase
HZ311_RS06945	ENOG4105E2R	ROK family
HZ311_RS06955	ENOG4105UP7	3-epimerase
HZ311_RS06960	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HZ311_RS06965	ENOG4105DM4	PTS System
HZ311_RS06970	ENOG4108YRF	PTS System
HZ311_RS06975	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
HZ311_RS06980	ENOG4108YRF	PTS System
HZ311_RS07140	ENOG4108UJD	30S ribosomal protein S9
HZ311_RS07145	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
HZ311_RS07155	ENOG4105CH7	arginosuccinase
HZ311_RS07170	ENOG4105HUF	DNA protection during starvation protein
HZ311_RS07175	ENOG4105CMG	Carbohydrate kinase
HZ311_RS07180	ENOG4106A3R	peptidase
HZ311_RS07185	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HZ311_RS07190	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HZ311_RS07195	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HZ311_RS07200	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
HZ311_RS07225	ENOG4105EAH	synthase
HZ311_RS07245	ENOG41088B0	Major membrane immunogen
HZ311_RS07320	ENOG4105DC8	reductase
HZ311_RS07325	ENOG4105CFP	Peptidase U32
HZ311_RS07330	ENOG4105XYU	peptidase (U32 family)
HZ311_RS07335	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HZ311_RS07340	ENOG4105KEX	transcriptional regulator, ctsr
HZ311_RS07420	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
HZ311_RS07425	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HZ311_RS07440	ENOG4105C3G	gtp-binding protein
HZ311_RS07445	ENOG4105VDK	protein, conserved in bacteria
HZ311_RS07450	ENOG4105FA0	parb-like partition protein
HZ311_RS07455	ENOG4107QJE	Chromosome Partitioning Protein
HZ311_RS07460	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
HZ311_RS07480	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
HZ311_RS07485	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
HZ311_RS07500	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HZ311_RS07505	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
HZ311_RS07510	ENOG4105VG0	50S ribosomal protein l34
HZ311_RS07515	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
HZ311_RS07520	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HZ311_RS07525	ENOG410848D	S4 domain protein YaaA
HZ311_RS07530	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HZ311_RS07535	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HZ311_RS07545	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
HZ311_RS07550	ENOG4108UUM	single-stranded DNA-binding protein
HZ311_RS07555	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
HZ311_RS07565	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
HZ311_RS07570	ENOG4105CDU	Replicative dna helicase
HZ311_RS07575	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
HZ311_RS07585	ENOG4105C5H	ABC transporter
HZ311_RS07595	ENOG4105C7K	acetolactate synthase
HZ311_RS07600	ENOG4105D9R	oxidoreductase
HZ311_RS07635	ENOG4105CS2	ec 3.2.1.21
HZ311_RS07640	ENOG4105CK1	PTS System
HZ311_RS07650	ENOG4105TPC	MazG nucleotide pyrophosphohydrolase domain
HZ311_RS07665	ENOG4105BZ1	(ABC) transporter
HZ311_RS07680	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HZ311_RS07685	ENOG4108UMI	ABC transporter, permease
HZ311_RS07690	ENOG4105D01	(LipO)protein
HZ311_RS07730	ENOG4105KAV	tspo and mbr like protein
HZ311_RS07750	ENOG4105XN3	extracellular solute-binding protein family 1
HZ311_RS07800	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HZ311_RS07805	ENOG4105CS9	pantothenic acid kinase
HZ311_RS07810	ENOG4105DUM	transcriptional regulator, lysR family
HZ311_RS07815	ENOG4107Y49	methyltransferase
HZ311_RS07825	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
HZ311_RS07830	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
HZ311_RS07835	ENOG4105KG3	cytidine deaminase
HZ311_RS07840	ENOG4105DIH	basic membrane
HZ311_RS07845	ENOG4108JQ9	ABC transporter
HZ311_RS07850	ENOG4105UIB	(ABC) transporter
HZ311_RS07860	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
HZ311_RS07870	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
HZ311_RS07885	ENOG4105WH1	Two component transcriptional regulator luxr family
HZ311_RS07890	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HZ311_RS07900	ENOG4105E66	phosphoriboisomerase A
HZ311_RS07905	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
HZ311_RS07910	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
HZ311_RS07915	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HZ311_RS07920	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HZ311_RS07925	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
HZ311_RS07930	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
HZ311_RS07935	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
HZ311_RS07940	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
HZ311_RS07945	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HZ311_RS07950	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
HZ311_RS07955	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
HZ311_RS07960	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
HZ311_RS07965	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
HZ311_RS07970	ENOG41082SA	50s ribosomal protein l29
HZ311_RS07975	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
HZ311_RS07980	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
HZ311_RS07985	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
HZ311_RS07990	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HZ311_RS07995	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HZ311_RS08000	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
HZ311_RS08005	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
HZ311_RS08010	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
HZ311_RS08015	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
HZ311_RS08020	ENOG4105VPB	50S ribosomal protein L30
HZ311_RS08025	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
HZ311_RS08030	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HZ311_RS08035	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HZ311_RS08040	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
HZ311_RS08045	ENOG41067V7	50S ribosomal protein L36
HZ311_RS08050	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HZ311_RS08055	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
HZ311_RS08060	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HZ311_RS08065	ENOG4108ZT0	50S ribosomal protein l17
HZ311_RS08070	ENOG4108JJB	ABC transporter
HZ311_RS08075	ENOG4108JJB	ABC transporter
HZ311_RS08095	ENOG4105VB9	50S ribosomal protein l28
HZ311_RS08105	ENOG4105DP4	dak2 domain fusion protein ylov
HZ311_RS08110	ENOG4105CB5	ATP-dependent DNA helicase recG
HZ311_RS08115	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
HZ311_RS08120	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HZ311_RS08130	ENOG4108JQ7	(ABC) transporter
HZ311_RS08135	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HZ311_RS08160	ENOG4105D5T	phosphonate abc transporter
HZ311_RS08170	ENOG4105WT3	Transcriptional regulator
HZ311_RS08175	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
HZ311_RS08180	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
HZ311_RS08185	ENOG410667J	hydrolase
HZ311_RS08190	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HZ311_RS08195	ENOG4105D9M	gamma-glutamylcysteine synthetase
HZ311_RS08205	ENOG4105DHS	permease protein
HZ311_RS08210	ENOG4105CM4	permease protein
HZ311_RS08215	ENOG4108IPW	abc transporter atp-binding protein
HZ311_RS08245	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
HZ311_RS08260	ENOG4105CHR	reductase
HZ311_RS08270	ENOG4105VKD	bioY protein
HZ311_RS08275	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
HZ311_RS08295	ENOG4105D48	metallophosphoesterase
HZ311_RS08305	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
HZ311_RS08315	ENOG4108Z03	MAF-like protein
HZ311_RS08335	ENOG4107414	GntR family transcriptional regulator
HZ311_RS08350	ENOG4105C5Y	PTS System
HZ311_RS08355	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
HZ311_RS08360	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
HZ311_RS08370	ENOG4105KJF	protein tyrosine phosphatase
HZ311_RS08380	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
HZ311_RS08385	ENOG4105CDA	abc transporter atp-binding protein
HZ311_RS08390	ENOG4105E5Q	amino acid AbC transporter
HZ311_RS08400	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
HZ311_RS08405	ENOG4108UW5	maltose o-acetyltransferase
HZ311_RS08410	ENOG4108Z3G	3H domain protein
HZ311_RS08435	ENOG4107YB9	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HZ311_RS08440	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
HZ311_RS08445	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HZ311_RS08455	ENOG4105DFH	Transport of potassium into the cell (By similarity)
HZ311_RS08465	ENOG4105C37	(CBS) domain
HZ311_RS08480	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
HZ311_RS08485	ENOG4105I08	Pseudouridine synthase
HZ311_RS08505	ENOG4105DBI	uridine monophosphokinase
HZ311_RS08510	ENOG4108HE4	integrase family
HZ311_RS08645	ENOG4105DVF	Cytosine-specific methyltransferase
HZ311_RS08820	ENOG4105E4C	Lytic transglycosylase catalytic
HZ311_RS08900	ENOG4107XJU	UPF0178 protein
HZ311_RS08920	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
HZ311_RS08925	ENOG4105C1J	atp-dependent rna helicase
HZ311_RS08935	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
HZ311_RS08940	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HZ311_RS08945	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
HZ311_RS08955	ENOG4105C0X	amino acid
HZ311_RS08970	ENOG4105R40	Glycine betaine carnitine choline
HZ311_RS08990	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
HZ311_RS09005	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
HZ311_RS09015	ENOG4105C0A	alcohol dehydrogenase
HZ311_RS09025	ENOG4105F5H	Glycosyl Hydrolase Family 88
HZ311_RS09030	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HZ311_RS09040	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HZ311_RS09055	ENOG4105J4Q	Transcriptional regulator
HZ311_RS09060	ENOG4108UHU	Aldolase
HZ311_RS09070	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
HZ311_RS09080	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
HZ311_RS09095	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
HZ311_RS09100	ENOG4105ZMH	deoxynucleoside kinase
HZ311_RS09105	ENOG4108M1A	Chitin-binding protein
HZ311_RS09115	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
HZ311_RS09125	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
HZ311_RS09155	ENOG41082UD	thioesterase Superfamily protein
HZ311_RS09160	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HZ311_RS09170	ENOG4108TZY	GntR Family Transcriptional Regulator
HZ311_RS09175	ENOG4105CK1	PTS System
HZ311_RS09180	ENOG4105CS2	ec 3.2.1.21
HZ311_RS09195	ENOG4105KWG	Pfam:DUF1696
HZ311_RS09200	ENOG4105C26	Dehydrogenase
HZ311_RS09215	ENOG410838F	Glycosyl transferase family 2
HZ311_RS09225	ENOG4105CN9	Peptidase m42 family protein
HZ311_RS09245	ENOG4108VDD	TRNA binding domain protein
HZ311_RS09250	ENOG4105C0H	protease
HZ311_RS09255	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
HZ311_RS09285	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
HZ311_RS09305	ENOG4105CZC	PTS system ascorbate-specific transporter subunit IIC
HZ311_RS09310	ENOG4108SU4	UPF0309 protein
HZ311_RS09340	ENOG4105D2N	Aldolase
HZ311_RS09360	ENOG4107REC	cytoplasmic protein
HZ311_RS09370	ENOG4105CSH	Transporter
HZ311_RS09375	ENOG4105C5B	carbamate kinase
HZ311_RS09385	ENOG4105C5Y	PTS System
HZ311_RS09390	ENOG4105CS2	ec 3.2.1.21
HZ311_RS09395	ENOG4105CID	antiterminator
HZ311_RS09400	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
HZ311_RS09415	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HZ311_RS09420	ENOG4105CPC	Aldo Keto reductase
HZ311_RS09425	ENOG4105C3F	Signal peptidase i
HZ311_RS09430	ENOG4105VZJ	PTS System
HZ311_RS09435	ENOG4105VCP	PTS System
HZ311_RS09440	ENOG4105CK1	PTS System
HZ311_RS09465	ENOG4105E2A	Dehydrogenase
HZ311_RS09485	ENOG4107SFZ	crispr-associated protein
HZ311_RS09550	ENOG4108U05	Transcriptional regulator
HZ311_RS09555	ENOG41090PH	Protease synthase and sporulation negative regulatory protein pai 1
HZ311_RS09575	ENOG4105C7N	Xanthine uracil vitamin C permease
HZ311_RS09620	ENOG4108CHM	Preferentially cleaves peptide bonds on the carboxyl- terminal side of aspartate and glutamate. Along with other extracellular proteases it is involved in colonization and infection of human tissues. Required for proteolytic maturation of thiol protease SspB and inactivation of SspC, an inhibitor of SspB. It is the most important protease for degradation of fibronectin-binding protein (FnBP) and surface protein A, which are involved in adherence to host cells. May also protect bacteria against host defense mechanism by cleaving the immunoglobulin classes IgG, IgA and IgM. May be involved in the stability of secreted lipases
HZ311_RS09625	ENOG4105VEQ	Cold shock protein
HZ311_RS09640	ENOG4105CG3	alpha amylase, catalytic region
HZ311_RS09650	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HZ311_RS09670	ENOG4107RBB	ABC transporter, permease
HZ311_RS09675	ENOG4105C19	ABC transporter
HZ311_RS09695	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
HZ311_RS09705	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
HZ311_RS09710	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
HZ311_RS09715	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
HZ311_RS09720	ENOG4105C0A	alcohol dehydrogenase
HZ311_RS09725	ENOG4108UW5	maltose o-acetyltransferase
HZ311_RS09735	ENOG4105DKG	l-rhamnose isomerase
HZ311_RS09740	ENOG4105DET	Rhamnulokinase
HZ311_RS09750	ENOG4105T16	Transcriptional regulator (AraC family)
HZ311_RS09760	ENOG4105C98	muts2 protein
HZ311_RS09765	ENOG4108UKJ	Cdp-alcohol phosphatidyltransferase
HZ311_RS09780	ENOG4108HCJ	Hydrolase
HZ311_RS09785	ENOG4105VPX	protein, conserved in bacteria
HZ311_RS09790	ENOG4105WZW	rhodanese family
HZ311_RS09795	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
HZ311_RS09805	ENOG4105CI1	PTS System
HZ311_RS09815	ENOG4105VDH	Dihydroxyacetone kinase
HZ311_RS09820	ENOG4105CMT	Dihydroxyacetone kinase
HZ311_RS09825	ENOG4108UTZ	Dihydroxyacetone kinase
HZ311_RS09845	ENOG4105E5D	amino acid
HZ311_RS09850	ENOG4105ETE	Transcriptional regulator (LacI family
HZ311_RS09860	ENOG4107URF	beta-phospho-glucomutase
HZ311_RS09870	ENOG4105CI1	PTS System
HZ311_RS09885	ENOG4105PY6	Phenolic acid decarboxylase
HZ311_RS09890	ENOG4105U3E	Transcriptional regulator
HZ311_RS09920	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HZ311_RS09930	ENOG4105BZU	Histidine kinase
HZ311_RS09970	ENOG4105C19	ABC transporter
HZ311_RS09985	ENOG4108Q3X	Transcriptional regulator
HZ311_RS09990	ENOG4105CI1	PTS System
HZ311_RS09995	ENOG4105F8D	glycoside hydrolase family 4
HZ311_RS10015	ENOG4108S4A	n-acetylmuramoyl-l-alanine amidase
HZ311_RS10020	ENOG4105ETE	Transcriptional regulator (LacI family
HZ311_RS10040	ENOG4105C02	permease
HZ311_RS10045	ENOG4105CG3	alpha amylase, catalytic region
HZ311_RS10055	ENOG4105DSE	periplasmic solute binding protein
HZ311_RS10070	ENOG410695V	Essential for the production of a quorum sensing system signal molecule, the autoinducing peptide (AIP). This quorum sensing system is responsible for the regulation of the expression of virulence factor genes. Involved in the proteolytic processing of AgrD, the precursor of AIP (By similarity)
HZ311_RS10080	ENOG4105C4R	Atp-dependent dna helicase
HZ311_RS10085	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
HZ311_RS10090	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
HZ311_RS10115	ENOG4108V06	Glutathione peroxidase
HZ311_RS10120	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
HZ311_RS10125	ENOG4105C28	cystathionine
HZ311_RS10130	ENOG4105C6T	cysteine synthase
HZ311_RS10135	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HZ311_RS10165	ENOG4108UT2	hemolysin iii
HZ311_RS10170	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
HZ311_RS10175	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
HZ311_RS10185	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
HZ311_RS10190	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
HZ311_RS10195	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HZ311_RS10200	ENOG4105CFH	Aspartokinase
HZ311_RS10205	ENOG4105CH2	amidohydrolase
HZ311_RS10210	ENOG4105CHM	Aminotransferase
HZ311_RS10215	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
HZ311_RS10235	ENOG4105DE4	1-phosphofructokinase
HZ311_RS10240	ENOG4105DM4	PTS System
HZ311_RS10245	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
HZ311_RS10250	ENOG4105D2M	Aldolase
HZ311_RS10260	ENOG4105E70	isomerase
HZ311_RS10265	ENOG4105D2M	Aldolase
HZ311_RS10270	ENOG4105DAS	pts system
HZ311_RS10275	ENOG4105ETZ	PTS System
HZ311_RS10280	ENOG4105F3R	pts system mannose fructose sorbose family iid
HZ311_RS10290	ENOG4105CS2	ec 3.2.1.21
HZ311_RS10305	ENOG4105M2Z	protein tyrosine serine phosphatase
HZ311_RS10325	ENOG4105C26	Dehydrogenase
HZ311_RS10360	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HZ311_RS10390	ENOG4105JVQ	RNA Polymerase
HZ311_RS10395	ENOG4108P49	AntiSigma factor
HZ311_RS10410	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HZ311_RS10415	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
HZ311_RS10420	ENOG4105D49	3-dehydroquinate synthase
HZ311_RS10425	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
HZ311_RS10440	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HZ311_RS10445	ENOG4105CQC	Prephenate dehydratase
HZ311_RS10460	ENOG4108Z0Z	intracellular protease Pfpi family
HZ311_RS10465	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
HZ311_RS10470	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
HZ311_RS10475	ENOG4108R6W	Transcriptional regulator, ARAC family
HZ311_RS10480	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
HZ311_RS10495	ENOG4105FDP	GntR family transcriptional regulator
HZ311_RS10510	ENOG4105CXK	mandelate racemase muconate lactonizing
HZ311_RS10515	ENOG4105C5Y	PTS System
HZ311_RS10560	ENOG4105T6C	Cell surface-associated protein implicated in virulence by promoting bacterial attachment to both alpha- and beta-chains of human fibrinogen and inducing the formation of bacterial clumps
HZ311_RS10630	ENOG4105UNS	Pfam:DUF419
HZ311_RS10640	ENOG4105D7V	transposase
HZ311_RS10650	ENOG4107X8C	Efflux transporter RND family MFP subunit
HZ311_RS10655	ENOG4105C19	ABC transporter
HZ311_RS10660	ENOG4107RBB	ABC transporter, permease
HZ311_RS10665	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HZ311_RS10670	ENOG4105BZU	Histidine kinase
HZ311_RS10680	ENOG4105DIK	(ABC) transporter
HZ311_RS10685	ENOG4105CC5	ABC transporter
HZ311_RS10690	ENOG4108XAN	ABC transporter
HZ311_RS10700	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
HZ311_RS10705	ENOG4108I7Y	domain protein
HZ311_RS10710	ENOG4107VFR	oxidoreductase
HZ311_RS10715	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HZ311_RS10725	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
HZ311_RS10735	ENOG4105WEF	catalase
HZ311_RS10740	ENOG4105CJZ	response regulator
HZ311_RS10745	ENOG4105EWM	Histidine kinase
HZ311_RS10750	ENOG4105CSC	Glucose uptake protein
HZ311_RS10755	ENOG4105CUB	amino acid
HZ311_RS10760	ENOG4105CDW	Resistance protein
HZ311_RS10770	ENOG4108YZ4	nudix hydrolase
HZ311_RS10780	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
HZ311_RS10795	ENOG4105C9K	Endothelin-converting enzyme 1
HZ311_RS10805	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HZ311_RS10810	ENOG4105C3J	Cysteine desulfurase
HZ311_RS10865	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HZ311_RS10870	ENOG4105C6X	Major Facilitator
HZ311_RS10895	ENOG4105E5Q	amino acid AbC transporter
HZ311_RS10900	ENOG4105CDA	abc transporter atp-binding protein
HZ311_RS10905	ENOG4106TNF	Periplasmic binding protein
HZ311_RS10910	ENOG4105CS2	ec 3.2.1.21
HZ311_RS10920	ENOG4105CNU	cell division protein FtsK
HZ311_RS10935	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HZ311_RS10955	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HZ311_RS10960	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HZ311_RS10970	ENOG4108JQ7	(ABC) transporter
HZ311_RS10975	ENOG4105D7V	transposase
HZ311_RS10990	ENOG4108RS6	transposase
HZ311_RS11000	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HZ311_RS11020	ENOG4107R7I	amino acid
HZ311_RS11025	ENOG4105F8V	Hydrolase, tatD family
HZ311_RS11030	ENOG4105HVR	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity)
HZ311_RS11035	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HZ311_RS11040	ENOG4105RNB	
HZ311_RS11045	ENOG4108IJ9	(ABC) transporter
HZ311_RS11060	ENOG4108Z5K	methylglyoxal synthase
HZ311_RS11070	ENOG4105BZ1	(ABC) transporter
HZ311_RS11080	ENOG4108M1A	Chitin-binding protein
HZ311_RS11090	ENOG4105E03	chitinase
HZ311_RS11095	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
HZ311_RS11110	ENOG4108SU4	UPF0309 protein
HZ311_RS11115	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
HZ311_RS11120	ENOG4105DYB	Isoaspartyl dipeptidase
HZ311_RS11135	ENOG4107WD8	ABC transporter, permease
HZ311_RS11150	ENOG4105E8R	UPF0173 metal-dependent hydrolase
HZ311_RS11160	ENOG4105SFS	phosphoesterase RecJ domain protein
HZ311_RS11165	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
HZ311_RS11195	ENOG4108Z6B	deaminase
HZ311_RS11205	ENOG4107R8B	5'-nucleotidase
HZ311_RS11210	ENOG4105MMD	transcriptional regulator
HZ311_RS11225	ENOG4108W5N	phosphatidylglycerophosphatase a
HZ311_RS11230	ENOG4105CAY	ferredoxin--nadp reductase
HZ311_RS11245	ENOG4105C87	Aminotransferase class I and II
HZ311_RS11295	ENOG4105CTZ	aminopeptidase c
HZ311_RS11310	ENOG4105HDK	L-asparaginase
HZ311_RS11315	ENOG4105I3N	Conserved Protein
HZ311_RS11320	ENOG410667J	hydrolase
HZ311_RS11330	ENOG4105DGY	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization (By similarity)
HZ311_RS11335	ENOG4105C3J	Cysteine desulfurase
HZ311_RS11340	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
HZ311_RS11345	ENOG4108YWR	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
HZ311_RS11350	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
HZ311_RS11355	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HZ311_RS11360	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
HZ311_RS11370	ENOG4108C33	Resolvase
HZ311_RS11555	ENOG4108TFU	terminase (Small subunit)
HZ311_RS11560	ENOG4105IG6	Phage terminase, large subunit
HZ311_RS11685	ENOG4105VEQ	Cold shock protein
HZ311_RS11695	ENOG4106EHS	UPF0356 protein
HZ311_RS11705	ENOG4105BZ1	(ABC) transporter
HZ311_RS11710	ENOG4108Z0R	Transferase
HZ311_RS11715	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HZ311_RS11725	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
HZ311_RS11730	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HZ311_RS11735	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HZ311_RS11740	ENOG4105KV4	Transcriptional regulator
HZ311_RS11745	ENOG4105C5F	glutamine synthetase
HZ311_RS11750	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HZ311_RS11760	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HZ311_RS11765	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
HZ311_RS11770	ENOG41082DI	50s ribosomal protein l31
HZ311_RS11775	ENOG4105CYP	glycoside hydrolase, family
HZ311_RS11780	ENOG4105CK1	PTS System
HZ311_RS11805	ENOG4105C6E	dna polymerase iii
HZ311_RS11810	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
HZ311_RS11815	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HZ311_RS11820	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
HZ311_RS11825	ENOG4105X0R	protein from nitrogen regulatory protein P-II
HZ311_RS11830	ENOG4105FA2	dna polymerase iii
HZ311_RS11835	ENOG4105MA4	psp1 domain protein
HZ311_RS11840	ENOG41063V3	Involved in initiation control of chromosome replication (By similarity)
HZ311_RS11845	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HZ311_RS11855	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
HZ311_RS11860	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
HZ311_RS11865	ENOG4105C19	ABC transporter
HZ311_RS11880	ENOG4108IQD	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity)
HZ311_RS11885	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
HZ311_RS11890	ENOG4105X96	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA (By similarity)
HZ311_RS11895	ENOG4108M4D	D-alanyl-lipoteichoic acid biosynthesis protein DltD
HZ311_RS11900	ENOG4105CN9	Peptidase m42 family protein
HZ311_RS11910	ENOG4108RQ5	Beta-lactamase domain-containing protein
HZ311_RS11915	ENOG4105DF9	Lipoate-protein, ligase
HZ311_RS11930	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
HZ311_RS11965	ENOG4105KA3	membrAne
HZ311_RS11970	ENOG4105CHH	sulfate transporter
HZ311_RS11975	ENOG4105VUF	Transcriptional regulator
HZ311_RS11985	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
HZ311_RS11995	ENOG4105K46	50S ribosomal protein l27
HZ311_RS12000	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HZ311_RS12005	ENOG4105DAS	pts system
HZ311_RS12015	ENOG4105ETZ	PTS System
HZ311_RS12020	ENOG4105F3R	pts system mannose fructose sorbose family iid
HZ311_RS12030	ENOG4107BMA	Transglycosylase associated protein
HZ311_RS12035	ENOG4105DC7	peptidase M24
HZ311_RS12040	ENOG4108ZSR	alkaline shock protein
HZ311_RS12045	ENOG4105M7K	Involved in the transcription termination process (By similarity)
HZ311_RS12050	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
HZ311_RS12055	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HZ311_RS12060	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HZ311_RS12065	ENOG4105CTB	Polyprenyl synthetase
HZ311_RS12070	ENOG4105DX0	Hemolysin A
HZ311_RS12075	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
HZ311_RS12080	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HZ311_RS12135	ENOG4105CJN	penicillin-binding protein
HZ311_RS12170	ENOG4105DFA	alanine racemase domain protein
HZ311_RS12175	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
HZ311_RS12185	ENOG4105DBK	s4 domain protein
HZ311_RS12190	ENOG4105MMF	Cell division protein DIVIVA
HZ311_RS12195	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HZ311_RS12205	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
HZ311_RS12210	ENOG4107RPQ	ABC transporter
HZ311_RS12225	ENOG4105EE0	oxidoreductase
HZ311_RS12235	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HZ311_RS12240	ENOG4105VZJ	PTS System
HZ311_RS12250	ENOG4105CK1	PTS System
HZ311_RS12290	ENOG4105C88	aminopeptidase
HZ311_RS12315	ENOG4107U9T	Pfam:Ribonuclease_BN
HZ311_RS12320	ENOG4105ESV	Glycosyl transferase, family 4
HZ311_RS12340	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
HZ311_RS12345	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
HZ311_RS12350	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HZ311_RS12355	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
HZ311_RS12375	ENOG4105EY8	ABC transporter
HZ311_RS12395	ENOG4108RYC	glycosyltransferase
HZ311_RS12400	ENOG4105KPE	licD family
HZ311_RS12425	ENOG4105KPE	licD family
HZ311_RS12455	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HZ311_RS12465	ENOG4105ENE	Histidine kinase
HZ311_RS12470	ENOG4105WH1	Two component transcriptional regulator luxr family
HZ311_RS12480	ENOG4105CJW	magnesium transporter
HZ311_RS12485	ENOG4107ZYR	domain protein
HZ311_RS12490	ENOG4105W8X	HesB YadR YfhF-family protein
HZ311_RS12495	ENOG4105C5I	Dehydrogenase
HZ311_RS12505	ENOG4105WH5	Teichoic acid glycosylation protein
HZ311_RS12510	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HZ311_RS12540	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
HZ311_RS12545	ENOG4108KGH	TRANSCRIPTIONal
HZ311_RS12555	ENOG4105KAV	tspo and mbr like protein
HZ311_RS12565	ENOG4108M1A	Chitin-binding protein
HZ311_RS12575	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
HZ311_RS12580	ENOG410902V	Modulates RecA activity (By similarity)
HZ311_RS12585	ENOG4105CEN	a g-specific adenine glycosylase
HZ311_RS12590	ENOG4105EVI	UPF0374 protein
HZ311_RS12595	ENOG4108HPG	-acetyltransferase
HZ311_RS12600	ENOG4105C02	permease
HZ311_RS12610	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
HZ311_RS12625	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HZ311_RS12630	ENOG4105KRI	phosphocarrier protein (HPr
HZ311_RS12635	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
HZ311_RS12640	ENOG4105W2C	Glycosyl transferase
HZ311_RS12645	ENOG4105BZF	Glycosyl transferase (Group 1
HZ311_RS12650	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HZ311_RS12655	ENOG4107IN1	Protein of unknown function (DUF1797)
HZ311_RS12660	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
HZ311_RS12670	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HZ311_RS12680	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HZ311_RS12685	ENOG4105CHR	reductase
HZ311_RS12690	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HZ311_RS12695	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
HZ311_RS12700	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HZ311_RS12705	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HZ311_RS12710	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
HZ311_RS12715	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
HZ311_RS12740	ENOG4108HW3	(ABC) transporter
HZ311_RS12745	ENOG4105E5Q	amino acid AbC transporter
HZ311_RS12750	ENOG4105CDA	abc transporter atp-binding protein
HZ311_RS12755	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
HZ311_RS12760	ENOG4105CQW	ribosome biogenesis GTPase YqeH
HZ311_RS12765	ENOG410812S	Rna-binding protein
HZ311_RS12770	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
HZ311_RS12775	ENOG4108WF2	Metal Dependent Phosphohydrolase
HZ311_RS12785	ENOG4105DXX	methyltransferase
HZ311_RS12790	ENOG4105CDE	UPF0348 protein
HZ311_RS12795	ENOG4105CDY	transcriptional regulatory protein
HZ311_RS12805	ENOG4105EEM	helicase
HZ311_RS12810	ENOG4105C59	p-type ATPase
HZ311_RS12815	ENOG41069HH	4-oxalocrotonate tautomerase
HZ311_RS12820	ENOG4105C22	threonyL-tRNA synthetase
HZ311_RS12840	ENOG4107RF6	penicillin-binding protein
HZ311_RS12845	ENOG4108KP7	hydrolase
HZ311_RS12850	ENOG4105C7N	Xanthine uracil vitamin C permease
HZ311_RS12855	ENOG4105C6X	Major Facilitator
HZ311_RS12865	ENOG4105C0B	DNA polymerase III (alpha subunit)
HZ311_RS12870	ENOG4105CTQ	phosphohexokinase
HZ311_RS12875	ENOG4105CA9	Pyruvate kinase
HZ311_RS12880	ENOG4107ZGM	malolactic fermentation system
HZ311_RS12895	ENOG41067VY	50S ribosomal protein L32
HZ311_RS12900	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
HZ311_RS12905	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HZ311_RS13020	ENOG4105CQ4	Transcriptional regulator
HZ311_RS13025	ENOG4105CQ4	Transcriptional regulator
HZ311_RS13055	ENOG4105DRS	transport system, permease
HZ311_RS13105	ENOG4105FBA	Phospholipase Carboxylesterase
HZ311_RS13115	ENOG4108TZY	GntR Family Transcriptional Regulator
HZ311_RS13120	ENOG4105CK1	PTS System
HZ311_RS13125	ENOG4105CS2	ec 3.2.1.21
HZ311_RS13130	ENOG4107YZX	Universal stress protein
HZ311_RS13135	ENOG4105DWF	phosphomethylpyrimidine kinase
HZ311_RS13140	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HZ311_RS13145	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
HZ311_RS13155	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
HZ311_RS13175	ENOG4108KGH	TRANSCRIPTIONal
HZ311_RS13215	ENOG4105MZU	cell filamentation protein
HZ311_RS13230	ENOG41065S2	pneumococcal vaccine antigen
HZ311_RS13240	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
HZ311_RS13245	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HZ311_RS13250	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HZ311_RS13255	ENOG41070VT	
HZ311_RS13260	ENOG4105QNR	S1 RNA binding domain protein
HZ311_RS13265	ENOG4105I3K	Ferric uptake regulator, Fur family
HZ311_RS13270	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HZ311_RS13280	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
HZ311_RS13285	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
HZ311_RS13290	ENOG4105FE9	pseudouridine synthase
HZ311_RS13295	ENOG4108SAX	Membrane
HZ311_RS13300	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
HZ311_RS13305	ENOG4107QSE	Dipeptidase
HZ311_RS13325	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HZ311_RS13335	ENOG4105CAT	Cytidine monophosphate kinase
HZ311_RS13340	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HZ311_RS13345	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HZ311_RS13350	ENOG4105K70	DNA-binding protein
HZ311_RS13360	ENOG41068YB	TPR repeat-containing protein
HZ311_RS13365	ENOG4108SXZ	UPF0302 protein
HZ311_RS13370	ENOG4108JYZ	YitT family
HZ311_RS13375	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
HZ311_RS13380	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HZ311_RS13395	ENOG4107SUZ	Sodium/hydrogen exchanger family
HZ311_RS13400	ENOG4105C5H	ABC transporter
HZ311_RS13405	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
HZ311_RS13415	ENOG4108RCR	degv family
HZ311_RS13420	ENOG41090WU	lipolytic protein G-D-S-L family
HZ311_RS13425	ENOG4105QZP	Uncharacterized protein conserved in bacteria (DUF2140)
HZ311_RS13435	ENOG4105VSD	UPF0346 protein
HZ311_RS13470	ENOG4105C79	DNA protecting protein DprA
HZ311_RS13475	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HZ311_RS13480	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
HZ311_RS13485	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HZ311_RS13490	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
HZ311_RS13495	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
HZ311_RS13500	ENOG4105EUM	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor (By similarity)
HZ311_RS13510	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
HZ311_RS13515	ENOG4105K4P	CoA-binding domain protein
HZ311_RS13520	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HZ311_RS13530	ENOG4105C6N	Formate acetyltransferase
HZ311_RS13535	ENOG4105F1A	Pyruvate formate-lyase
HZ311_RS13540	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
HZ311_RS13555	ENOG4108U5N	UPF0316 protein
HZ311_RS13560	ENOG4108MXZ	Esterase
HZ311_RS13565	ENOG4105FKQ	transcriptional regulator
HZ311_RS13575	ENOG4105CIS	alcohol dehydrogenase
HZ311_RS13580	ENOG4108JYZ	YitT family
HZ311_RS13595	ENOG4108IJ8	ABC transporter
HZ311_RS13625	ENOG4105VRS	hydrolase family 18
HZ311_RS13655	ENOG4105CHM	Aminotransferase
HZ311_RS13665	ENOG4105CE4	GlcNAc 6-P deacetylase
HZ311_RS13670	ENOG4105W1Y	Transcriptional regulator
HZ311_RS13685	ENOG4105ZT7	DNA-entry nuclease
HZ311_RS13695	ENOG4105DZ6	Band 7 protein
HZ311_RS13705	ENOG4108QEG	Membrane
HZ311_RS13720	ENOG4108VXD	carboxy-peptidase
HZ311_RS13725	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
HZ311_RS13735	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
HZ311_RS13740	ENOG4105C2W	permease
HZ311_RS13750	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HZ311_RS13755	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HZ311_RS13760	ENOG4105C83	adenylosuccinate lyase
HZ311_RS13770	ENOG4105C8V	SAICAR synthetase
HZ311_RS13775	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
HZ311_RS13780	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
HZ311_RS13785	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
HZ311_RS13790	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
HZ311_RS13795	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
HZ311_RS13800	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HZ311_RS13805	ENOG4105DC1	bifunctional purine biosynthesis protein purh
HZ311_RS13810	ENOG4105C12	Phosphoribosylglycinamide synthetase
HZ311_RS13815	ENOG4107QM2	Aldo Keto reductase
HZ311_RS13825	ENOG4107SJ1	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity)
HZ311_RS13840	ENOG4105CPP	Dehydrogenase, E1 component
HZ311_RS13845	ENOG4105C7S	Dehydrogenase
HZ311_RS13855	ENOG4105WBI	UPF0223 protein
HZ311_RS13860	ENOG4105ECY	inositol monophosphatase
HZ311_RS13870	ENOG4105CI3	gtp-binding protein typa
HZ311_RS13880	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HZ311_RS13885	ENOG4105ZPI	UPF0358 protein
HZ311_RS13890	ENOG4105CNI	cell division protein FtsW
HZ311_RS13895	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
HZ311_RS13910	ENOG4105WUC	UPF0298 protein
HZ311_RS13915	ENOG4106H78	methyltransferase
HZ311_RS13920	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
HZ311_RS13925	ENOG41063PX	domain protein
HZ311_RS13935	ENOG4105KQC	Competence protein
HZ311_RS13940	ENOG4108UK2	deaminase
HZ311_RS13950	ENOG4105TQK	DNA polymerase iii, delta' subunit
HZ311_RS13955	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
HZ311_RS13965	ENOG4108VMM	UPF0756 membrane protein
HZ311_RS14000	ENOG4105NTW	Transcriptional regulator
HZ311_RS14005	ENOG4105C5H	ABC transporter
HZ311_RS14010	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
HZ311_RS14025	ENOG4105DVT	helicase
HZ311_RS14030	ENOG4108VPT	UPF0234 protein
HZ311_RS14035	ENOG4107AYK	membrAne
HZ311_RS14040	ENOG4105VG1	fes assembly suf system protein
HZ311_RS14045	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HZ311_RS14120	ENOG4107QYX	exodeoxyribonuclease v alpha
HZ311_RS14165	ENOG4108UXE	Protein tyrosine phosphatase
HZ311_RS14175	ENOG4105VRS	hydrolase family 18
HZ311_RS14230	ENOG4105DUX	Transporter
HZ311_RS14235	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
HZ311_RS14240	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
HZ311_RS14250	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
HZ311_RS14255	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
HZ311_RS14265	ENOG4105CDA	abc transporter atp-binding protein
HZ311_RS14270	ENOG4105CT1	(ABC) transporter
HZ311_RS14275	ENOG4105EAD	ABC transporter
HZ311_RS14280	ENOG4105DRP	amino acid AbC transporter
HZ311_RS14285	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HZ311_RS14290	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
HZ311_RS14305	ENOG4105D8X	mechanosensitive ion channel
HZ311_RS14310	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HZ311_RS14315	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
HZ311_RS14320	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HZ311_RS14325	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
HZ311_RS14340	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HZ311_RS14350	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
HZ311_RS14355	ENOG4108IXY	short-chain dehydrogenase reductase
HZ311_RS14365	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HZ311_RS14370	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
HZ311_RS14380	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HZ311_RS14395	ENOG4107X35	defense response to bacterium
HZ311_RS14405	ENOG4105C6T	cysteine synthase
HZ311_RS14410	ENOG4105G5W	regulator Fur family
HZ311_RS14415	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
HZ311_RS14430	ENOG4105CSM	endonuclease III
HZ311_RS14445	ENOG4108M1A	Chitin-binding protein
HZ311_RS14480	ENOG4105K4H	Nlp p60 protein
HZ311_RS14535	ENOG4105BZ4	penicillin-binding protein
HZ311_RS14540	ENOG4108UI2	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity)
HZ311_RS14545	ENOG4108UKS	UPF0398 protein
HZ311_RS14550	ENOG4105XWG	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity)
HZ311_RS14560	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
HZ311_RS14570	ENOG4105CTD	carboxy-peptidase
HZ311_RS14590	ENOG4105C1J	atp-dependent rna helicase
HZ311_RS14600	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HZ311_RS14615	ENOG4105VND	Ribonuclease
HZ311_RS14620	ENOG41075Z0	
HZ311_RS14625	ENOG4105VEQ	Cold shock protein
HZ311_RS14630	ENOG4105CKU	formyltetrahydrofolate synthetase
HZ311_RS14670	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HZ311_RS14675	ENOG4105C34	Pseudouridine synthase
HZ311_RS14690	ENOG4105CXT	aspartate transcarbamylase
HZ311_RS14695	ENOG4105CD3	dihydroorotase
HZ311_RS14700	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
HZ311_RS14705	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HZ311_RS14710	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
HZ311_RS14715	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
HZ311_RS14720	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
HZ311_RS14740	ENOG4107RSM	transcriptional regulator
HZ311_RS14765	ENOG4105C7J	ABC transporter, permease
HZ311_RS14770	ENOG4105D5T	phosphonate abc transporter
HZ311_RS14775	ENOG4105E2X	shikimate dehydrogenase
HZ311_RS14780	ENOG4108RCF	TRANSCRIPTIONal
HZ311_RS14845	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HZ311_RS14930	ENOG4105E4C	Lytic transglycosylase catalytic
HZ311_RS14950	ENOG4108S4A	n-acetylmuramoyl-l-alanine amidase
HZ311_RS15000	ENOG4107QJE	Chromosome Partitioning Protein
HZ311_RS15065	ENOG4108ZJ4	polysaccharide deacetylase
HZ311_RS15080	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HZ311_RS15085	ENOG4105MN3	Resolvase
HZ311_RS15090	ENOG4105MZU	cell filamentation protein
HZ311_RS15145	ENOG4105ZT7	DNA-entry nuclease
HZ311_RS15155	ENOG4108UUM	single-stranded DNA-binding protein
HZ311_RS15250	ENOG4106128	DNA-binding helix-turn-helix protein
HZ311_RS15255	ENOG4106BHR	ftsk SpoIIIE family protein
HZ311_RS15305	ENOG4107QJE	Chromosome Partitioning Protein
HZ311_RS15360	ENOG4105MN3	Resolvase
HZ311_RS15365	ENOG4105MZU	cell filamentation protein
HZ311_RS15380	ENOG4105VEQ	Cold shock protein
HZ311_RS15480	ENOG4105BZU	Histidine kinase
HZ311_RS15485	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HZ311_RS15490	ENOG4107RBB	ABC transporter, permease
HZ311_RS15495	ENOG4105C19	ABC transporter
HZ311_RS15500	ENOG4107X8C	Efflux transporter RND family MFP subunit
HZ311_RS15530	ENOG4105T6C	Cell surface-associated protein implicated in virulence by promoting bacterial attachment to both alpha- and beta-chains of human fibrinogen and inducing the formation of bacterial clumps
HZ311_RS15610	ENOG4105DVF	Cytosine-specific methyltransferase
HZ311_RS15620	ENOG4105MU5	relaxase mobilization nuclease domain protein