locus-tag	class	description
DDJ96_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DDJ96_RS00010	COG0592	DNA-directed DNA polymerase activity
DDJ96_RS00015	COG2501	S4 domain
DDJ96_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DDJ96_RS00025	COG0187	DNA topoisomerase II activity
DDJ96_RS00035	COG0360	Binds together with S18 to 16S ribosomal RNA
DDJ96_RS00040	COG0629	single-stranded DNA binding
DDJ96_RS00045	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DDJ96_RS00055	COG0359	binds to the 23S rRNA
DDJ96_RS00060	COG0305	Participates in initiation and elongation during chromosome replication
DDJ96_RS00065	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DDJ96_RS00080	COG0488	(ABC) transporter
DDJ96_RS00090	COG0028	Belongs to the TPP enzyme family
DDJ96_RS00095	COG0673	inositol 2-dehydrogenase activity
DDJ96_RS00125	COG2723	6-phospho-beta-galactosidase activity
DDJ96_RS00130	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DDJ96_RS00140	COG1694	Mazg nucleotide pyrophosphohydrolase
DDJ96_RS00155	COG1132	(ABC) transporter
DDJ96_RS00175	COG2011	ABC-type metal ion transport system permease component
DDJ96_RS00180	COG1464	Belongs to the NlpA lipoprotein family
DDJ96_RS00220	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
DDJ96_RS00245	COG1653	transport
DDJ96_RS00295	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DDJ96_RS00295	COG0519	Catalyzes the synthesis of GMP from XMP
DDJ96_RS00300	COG1072	(Pantothenic acid kinase))
DDJ96_RS00305	COG0583	DNA-binding transcription factor activity
DDJ96_RS00310	COG2813	Specifically methylates the guanine in position
DDJ96_RS00315	COG1609	Transcriptional regulator
DDJ96_RS00320	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
DDJ96_RS00325	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DDJ96_RS00330	COG0295	cytidine deaminase activity
DDJ96_RS00335	COG1744	ABC transporter substrate-binding protein PnrA-like
DDJ96_RS00340	COG3845	ABC transporter
DDJ96_RS00345	COG4603	Belongs to the binding-protein-dependent transport system permease family
DDJ96_RS00350	COG1079	Belongs to the binding-protein-dependent transport system permease family
DDJ96_RS00355	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
DDJ96_RS00365	COG0813	purine-nucleoside phosphorylase activity
DDJ96_RS00380	COG2197	response regulator
DDJ96_RS00385	COG0588	phosphoglycerate mutase activity
DDJ96_RS00390	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DDJ96_RS00395	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DDJ96_RS00400	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DDJ96_RS00405	COG0049	tRNA binding
DDJ96_RS00410	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DDJ96_RS00415	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DDJ96_RS00420	COG0051	transcription antitermination factor activity, RNA binding
DDJ96_RS00425	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DDJ96_RS00430	COG0088	Forms part of the polypeptide exit tunnel
DDJ96_RS00435	COG0089	rRNA binding
DDJ96_RS00440	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DDJ96_RS00445	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DDJ96_RS00450	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DDJ96_RS00455	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DDJ96_RS00460	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DDJ96_RS00465	COG0255	Belongs to the universal ribosomal protein uL29 family
DDJ96_RS00470	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DDJ96_RS00475	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DDJ96_RS00480	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DDJ96_RS00485	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DDJ96_RS00490	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DDJ96_RS00495	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DDJ96_RS00500	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DDJ96_RS00505	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DDJ96_RS00510	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DDJ96_RS00515	COG1841	ribosomal large subunit assembly
DDJ96_RS00520	COG0200	Binds to the 23S rRNA
DDJ96_RS00525	COG0201	protein transport
DDJ96_RS00530	COG0563	adenylate kinase activity
DDJ96_RS00535	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DDJ96_RS00540	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DDJ96_RS00545	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DDJ96_RS00550	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DDJ96_RS00555	COG0202	RNA polymerase activity
DDJ96_RS00560	COG0203	ribosomal protein L17
DDJ96_RS00565	COG1122	ATPase activity
DDJ96_RS00570	COG1122	ATPase activity
DDJ96_RS00590	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DDJ96_RS00605	COG1461	Dihydroxyacetone kinase
DDJ96_RS00610	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DDJ96_RS00615	COG0416	fatty acid biosynthetic process
DDJ96_RS00620	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DDJ96_RS00630	COG4608	Belongs to the ABC transporter superfamily
DDJ96_RS00635	COG0601	transmembrane transport
DDJ96_RS00660	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
DDJ96_RS00670	COG1396	sequence-specific DNA binding
DDJ96_RS00675	COG0571	ribonuclease III activity
DDJ96_RS00680	COG1196	nuclear chromosome segregation
DDJ96_RS00685	COG0561	phosphatase activity
DDJ96_RS00690	COG0552	protein localization to endoplasmic reticulum
DDJ96_RS00695	COG1181	Belongs to the D-alanine--D-alanine ligase family
DDJ96_RS00695	COG2918	glutathione biosynthetic process
DDJ96_RS00705	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDJ96_RS00710	COG4605	iron ion homeostasis
DDJ96_RS00715	COG4604	ABC transporter, ATP-binding protein
DDJ96_RS00720	COG4607	ABC-type enterochelin transport system periplasmic component
DDJ96_RS00745	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DDJ96_RS00760	COG1028	Short-chain dehydrogenase reductase Sdr
DDJ96_RS00770	COG1268	BioY protein
DDJ96_RS00775	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DDJ96_RS00790	COG0561	phosphatase activity
DDJ96_RS00795	COG1692	metallophosphoesterase
DDJ96_RS00805	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DDJ96_RS00815	COG0424	maF-like protein
DDJ96_RS00830	COG2188	Transcriptional regulator
DDJ96_RS00845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDJ96_RS00845	COG1263	PTS System
DDJ96_RS00850	COG0632	four-way junction helicase activity
DDJ96_RS00855	COG2255	four-way junction helicase activity
DDJ96_RS00865	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DDJ96_RS00875	COG1114	Component of the transport system for branched-chain amino acids
DDJ96_RS00880	COG1126	abc transporter atp-binding protein
DDJ96_RS00885	COG0765	amino acid transport
DDJ96_RS00895	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DDJ96_RS00900	COG0110	maltose O-acetyltransferase activity
DDJ96_RS00905	COG1827	regulation of RNA biosynthetic process
DDJ96_RS00925	COG0242	peptide deformylase activity
DDJ96_RS00930	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DDJ96_RS00935	COG1185	polyribonucleotide nucleotidyltransferase activity
DDJ96_RS00945	COG3158	transport of potassium into the cell
DDJ96_RS00955	COG1253	flavin adenine dinucleotide binding
DDJ96_RS00960	COG0534	Mate efflux family protein
DDJ96_RS00970	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DDJ96_RS00975	COG1187	pseudouridine synthase activity
DDJ96_RS00990	COG1011	Hydrolase
DDJ96_RS00995	COG0572	uridine kinase
DDJ96_RS01015	COG1671	Belongs to the UPF0178 family
DDJ96_RS01030	COG1181	Belongs to the D-alanine--D-alanine ligase family
DDJ96_RS01035	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DDJ96_RS01050	COG0736	holo-[acyl-carrier-protein] synthase activity
DDJ96_RS01060	COG2337	Toxic component of a toxin-antitoxin (TA) module
DDJ96_RS01075	COG0531	amino acid
DDJ96_RS01110	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DDJ96_RS01125	COG0343	queuine tRNA-ribosyltransferase activity
DDJ96_RS01130	COG1862	Preprotein translocase
DDJ96_RS01135	COG1454	alcohol dehydrogenase
DDJ96_RS01135	COG1012	belongs to the aldehyde dehydrogenase family
DDJ96_RS01145	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DDJ96_RS01175	COG1414	Transcriptional regulator
DDJ96_RS01180	COG0800	Aldolase
DDJ96_RS01190	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
DDJ96_RS01195	COG1028	Short-chain dehydrogenase reductase Sdr
DDJ96_RS01200	COG1304	FMN binding
DDJ96_RS01215	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DDJ96_RS01220	COG1428	Deoxynucleoside kinase
DDJ96_RS01225	COG3397	chitin binding
DDJ96_RS01230	COG3397	chitin binding
DDJ96_RS01235	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DDJ96_RS01245	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DDJ96_RS01270	COG0824	Thioesterase
DDJ96_RS01275	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DDJ96_RS01285	COG2188	Transcriptional regulator
DDJ96_RS01290	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DDJ96_RS01295	COG2723	6-phospho-beta-galactosidase activity
DDJ96_RS01315	COG1012	belongs to the aldehyde dehydrogenase family
DDJ96_RS01340	COG1363	Peptidase, m42
DDJ96_RS01345	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DDJ96_RS01360	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DDJ96_RS01365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DDJ96_RS01370	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DDJ96_RS01400	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
DDJ96_RS01405	COG3711	transcriptional antiterminator
DDJ96_RS01405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDJ96_RS01425	COG4821	SIS domain
DDJ96_RS01475	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DDJ96_RS01485	COG0477	Major facilitator Superfamily
DDJ96_RS01490	COG0549	Belongs to the carbamate kinase family
DDJ96_RS01500	COG1263	PTS System
DDJ96_RS01500	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDJ96_RS01500	COG2190	(PTS) system
DDJ96_RS01505	COG2723	6-phospho-beta-galactosidase activity
DDJ96_RS01510	COG3711	transcriptional antiterminator
DDJ96_RS01515	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DDJ96_RS01530	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DDJ96_RS01535	COG0667	Aldo Keto reductase
DDJ96_RS01540	COG0681	Belongs to the peptidase S26 family
DDJ96_RS01545	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DDJ96_RS01550	COG1447	Phosphotransferase system cellobiose-specific component IIA
DDJ96_RS01555	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DDJ96_RS01580	COG1063	alcohol dehydrogenase
DDJ96_RS01605	COG1518	maintenance of DNA repeat elements
DDJ96_RS01610	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DDJ96_RS01650	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DDJ96_RS01665	COG1846	Transcriptional regulator
DDJ96_RS01670	COG0456	acetyltransferase
DDJ96_RS01690	COG2252	PERMEase
DDJ96_RS01745	COG1278	Cold shock
DDJ96_RS01760	COG0366	Alpha amylase catalytic
DDJ96_RS01780	COG1902	pentaerythritol trinitrate reductase activity
DDJ96_RS01790	COG0656	L-ascorbic acid biosynthetic process
DDJ96_RS01800	COG0577	efflux transmembrane transporter activity
DDJ96_RS01805	COG1136	(ABC) transporter
DDJ96_RS01825	COG0446	pyridine nucleotide-disulphide oxidoreductase
DDJ96_RS01835	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DDJ96_RS01840	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DDJ96_RS01845	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DDJ96_RS01850	COG1454	alcohol dehydrogenase
DDJ96_RS01865	COG4806	L-rhamnose isomerase
DDJ96_RS01870	COG1070	Carbohydrate kinase
DDJ96_RS01880	COG2207	Transcriptional regulator
DDJ96_RS01880	COG1609	Transcriptional regulator
DDJ96_RS01890	COG1193	negative regulation of DNA recombination
DDJ96_RS01895	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DDJ96_RS01905	COG1609	Transcriptional regulator
DDJ96_RS01910	COG0561	phosphatase activity
DDJ96_RS01915	COG1937	Protein conserved in bacteria
DDJ96_RS01920	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DDJ96_RS01925	COG0446	pyridine nucleotide-disulphide oxidoreductase
DDJ96_RS01935	COG2190	(PTS) system
DDJ96_RS01935	COG1263	PTS System
DDJ96_RS01935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDJ96_RS01945	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
DDJ96_RS01950	COG2376	Dihydroxyacetone kinase
DDJ96_RS01955	COG1461	Dihydroxyacetone kinase
DDJ96_RS01975	COG0531	amino acid
DDJ96_RS01980	COG1609	Transcriptional regulator
DDJ96_RS01990	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DDJ96_RS02000	COG2190	(PTS) system
DDJ96_RS02000	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDJ96_RS02000	COG1263	PTS System
DDJ96_RS02015	COG3479	Phenolic acid decarboxylase
DDJ96_RS02020	COG1695	Transcriptional regulator
DDJ96_RS02030	COG2814	Major facilitator Superfamily
DDJ96_RS02050	COG1136	(ABC) transporter
DDJ96_RS02050	COG0577	efflux transmembrane transporter activity
DDJ96_RS02060	COG3850	Histidine kinase
DDJ96_RS02060	COG5002	protein histidine kinase activity
DDJ96_RS02100	COG1136	(ABC) transporter
DDJ96_RS02115	COG1737	Transcriptional regulator
DDJ96_RS02120	COG1263	PTS System
DDJ96_RS02120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDJ96_RS02125	COG1486	melibiose metabolic process
DDJ96_RS02145	COG3942	CHAP domain
DDJ96_RS02145	COG1705	Flagellar rod assembly protein muramidase FlgJ
DDJ96_RS02150	COG1609	Transcriptional regulator
DDJ96_RS02170	COG0628	permease
DDJ96_RS02175	COG0366	Alpha amylase catalytic
DDJ96_RS02180	COG0628	permease
DDJ96_RS02185	COG3443	Belongs to the bacterial solute-binding protein 9 family
DDJ96_RS02185	COG0803	Belongs to the bacterial solute-binding protein 9 family
DDJ96_RS02210	COG0210	DNA helicase
DDJ96_RS02215	COG1393	Belongs to the ArsC family
DDJ96_RS02220	COG1393	Belongs to the ArsC family
DDJ96_RS02245	COG0386	Belongs to the glutathione peroxidase family
DDJ96_RS02250	COG1854	S-ribosylhomocysteine lyase activity
DDJ96_RS02255	COG0626	cystathionine gamma-synthase activity
DDJ96_RS02260	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DDJ96_RS02265	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DDJ96_RS02295	COG1272	protein, Hemolysin III
DDJ96_RS02300	COG0019	diaminopimelate decarboxylase activity
DDJ96_RS02305	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DDJ96_RS02315	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DDJ96_RS02320	COG2171	N-acyltransferase activity
DDJ96_RS02325	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DDJ96_RS02330	COG0527	aspartate kinase activity
DDJ96_RS02335	COG1473	amidohydrolase
DDJ96_RS02340	COG0436	Aminotransferase
DDJ96_RS02345	COG0446	pyridine nucleotide-disulphide oxidoreductase
DDJ96_RS02370	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDJ96_RS02370	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDJ96_RS02370	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDJ96_RS02375	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDJ96_RS02375	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDJ96_RS02375	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DDJ96_RS02380	COG3684	Belongs to the aldolase LacD family
DDJ96_RS02385	COG2188	Transcriptional regulator
DDJ96_RS02390	COG2222	sugar isomerase
DDJ96_RS02395	COG3684	Belongs to the aldolase LacD family
DDJ96_RS02400	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDJ96_RS02400	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDJ96_RS02405	COG3715	PTS system
DDJ96_RS02410	COG3716	PTS system mannose fructose sorbose family IID component
DDJ96_RS02420	COG2723	6-phospho-beta-galactosidase activity
DDJ96_RS02435	COG2365	Tyrosine phosphatase family
DDJ96_RS02455	COG1012	belongs to the aldehyde dehydrogenase family
DDJ96_RS02495	COG1233	COG1233 Phytoene dehydrogenase and related
DDJ96_RS02520	COG1595	DNA-templated transcription, initiation
DDJ96_RS02540	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DDJ96_RS02545	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DDJ96_RS02550	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DDJ96_RS02555	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DDJ96_RS02570	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DDJ96_RS02575	COG0077	Prephenate dehydratase
DDJ96_RS02590	COG0693	protein deglycase activity
DDJ96_RS02595	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DDJ96_RS02605	COG2207	Transcriptional regulator
DDJ96_RS02610	COG2249	NAD(P)H dehydrogenase (quinone) activity
DDJ96_RS02620	COG2188	Transcriptional regulator
DDJ96_RS02645	COG2190	(PTS) system
DDJ96_RS02645	COG1263	PTS System
DDJ96_RS02645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDJ96_RS02665	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
DDJ96_RS02690	COG4932	domain protein
DDJ96_RS02690	COG4886	Leucine-rich repeat (LRR) protein
DDJ96_RS02720	COG3711	transcriptional antiterminator
DDJ96_RS02760	COG2315	Protein conserved in bacteria
DDJ96_RS02780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DDJ96_RS02785	COG1136	(ABC) transporter
DDJ96_RS02790	COG0577	efflux transmembrane transporter activity
DDJ96_RS02795	COG0745	RESPONSE REGULATOR receiver
DDJ96_RS02800	COG5002	protein histidine kinase activity
DDJ96_RS02805	COG1113	amino acid transport
DDJ96_RS02810	COG1121	(ABC) transporter
DDJ96_RS02815	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DDJ96_RS02830	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DDJ96_RS02835	COG2823	Periplasmic or secreted lipoprotein
DDJ96_RS02835	COG1652	LysM domain
DDJ96_RS02840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DDJ96_RS02845	COG0477	Major facilitator Superfamily
DDJ96_RS02855	COG1438	arginine binding
DDJ96_RS02865	COG3546	catalase activity
DDJ96_RS02870	COG0745	RESPONSE REGULATOR receiver
DDJ96_RS02875	COG0642	Histidine kinase
DDJ96_RS02880	COG4975	Glucose uptake
DDJ96_RS02885	COG0531	amino acid
DDJ96_RS02890	COG3853	Toxic anion resistance protein (TelA)
DDJ96_RS02900	COG0494	nUDIX hydrolase
DDJ96_RS02910	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DDJ96_RS02915	COG1335	isochorismatase
DDJ96_RS02930	COG3590	peptidase
DDJ96_RS02940	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DDJ96_RS02945	COG1104	cysteine desulfurase activity
DDJ96_RS03030	COG0482	sulfurtransferase activity
DDJ96_RS03035	COG2814	Major facilitator Superfamily
DDJ96_RS03065	COG0765	amino acid transport
DDJ96_RS03070	COG1126	abc transporter atp-binding protein
DDJ96_RS03075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DDJ96_RS03080	COG2723	6-phospho-beta-galactosidase activity
DDJ96_RS03090	COG1280	lysine exporter protein (LysE YggA)
DDJ96_RS03090	COG1674	ftsk spoiiie
DDJ96_RS03105	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DDJ96_RS03115	COG4166	transmembrane transport
DDJ96_RS03125	COG0601	transmembrane transport
DDJ96_RS03130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DDJ96_RS03135	COG0444	Belongs to the ABC transporter superfamily
DDJ96_RS03140	COG4608	Belongs to the ABC transporter superfamily
DDJ96_RS03145	COG0675	Transposase, IS605 OrfB family
DDJ96_RS03180	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DDJ96_RS03180	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DDJ96_RS03185	COG3177	Filamentation induced by cAMP protein fic
DDJ96_RS03195	COG0531	amino acid
DDJ96_RS03200	COG0084	hydrolase, TatD family'
DDJ96_RS03205	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DDJ96_RS03210	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DDJ96_RS03220	COG3842	ATPase activity
DDJ96_RS03235	COG1803	Methylglyoxal synthase
DDJ96_RS03245	COG1132	(ABC) transporter
DDJ96_RS03265	COG3469	chitinase activity
DDJ96_RS03270	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DDJ96_RS03285	COG4821	SIS domain
DDJ96_RS03290	COG1288	antiporter activity
DDJ96_RS03305	COG1136	(ABC) transporter
DDJ96_RS03310	COG0577	efflux transmembrane transporter activity
DDJ96_RS03325	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DDJ96_RS03330	COG4109	DRTGG domain
DDJ96_RS03335	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DDJ96_RS03340	COG2824	Alkylphosphonate utilization operon protein PhnA
DDJ96_RS03345	COG2738	Putative neutral zinc metallopeptidase
DDJ96_RS03370	COG0590	tRNA wobble adenosine to inosine editing
DDJ96_RS03380	COG0737	Belongs to the 5'-nucleotidase family
DDJ96_RS03385	COG4470	Protein conserved in bacteria
DDJ96_RS03400	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DDJ96_RS03405	COG0492	ferredoxin-NADP+ reductase activity
DDJ96_RS03420	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DDJ96_RS03425	COG1098	S1 RNA binding domain
DDJ96_RS03470	COG3579	cysteine-type endopeptidase activity
DDJ96_RS03490	COG1801	Protein of unknown function DUF72
DDJ96_RS03495	COG0561	phosphatase activity
DDJ96_RS03505	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DDJ96_RS03510	COG1104	cysteine desulfurase activity
DDJ96_RS03515	COG0301	tRNA thio-modification
DDJ96_RS03520	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DDJ96_RS03525	COG0525	valine-tRNA ligase activity
DDJ96_RS03530	COG0285	dihydrofolate synthase activity
DDJ96_RS03535	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DDJ96_RS03540	COG2003	Belongs to the UPF0758 family
DDJ96_RS03545	COG1278	Cold shock
DDJ96_RS03555	COG5503	Protein of unknown function (DUF1447)
DDJ96_RS03565	COG1132	(ABC) transporter
DDJ96_RS03570	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DDJ96_RS03575	COG0740	serine-type endopeptidase activity
DDJ96_RS03585	COG0584	glycerophosphoryl diester phosphodiesterase
DDJ96_RS03590	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DDJ96_RS03595	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DDJ96_RS03600	COG0789	Transcriptional regulator
DDJ96_RS03605	COG0174	glutamine synthetase
DDJ96_RS03615	COG0504	CTP synthase activity
DDJ96_RS03625	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DDJ96_RS03630	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DDJ96_RS03635	COG0254	rRNA binding
DDJ96_RS03640	COG4733	cellulase activity
DDJ96_RS03640	COG5297	Belongs to the glycosyl hydrolase family 6
DDJ96_RS03645	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DDJ96_RS03670	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DDJ96_RS03675	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DDJ96_RS03680	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DDJ96_RS03685	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DDJ96_RS03690	COG3870	Protein conserved in bacteria
DDJ96_RS03695	COG0470	DNA polymerase III
DDJ96_RS03700	COG1774	PSP1 C-terminal conserved region
DDJ96_RS03705	COG4467	Involved in initiation control of chromosome replication
DDJ96_RS03730	COG0602	queuosine metabolic process
DDJ96_RS03735	COG1328	CTP reductase activity
DDJ96_RS03740	COG1136	(ABC) transporter
DDJ96_RS03745	COG0577	efflux transmembrane transporter activity
DDJ96_RS03755	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DDJ96_RS03760	COG1696	Membrane protein involved in D-alanine export
DDJ96_RS03765	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DDJ96_RS03770	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DDJ96_RS03775	COG1363	Peptidase, m42
DDJ96_RS03785	COG1234	tRNA 3'-trailer cleavage
DDJ96_RS03790	COG0095	Lipoate-protein ligase
DDJ96_RS03805	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DDJ96_RS03840	COG3759	membrane
DDJ96_RS03845	COG0659	secondary active sulfate transmembrane transporter activity
DDJ96_RS03850	COG0789	Transcriptional regulator
DDJ96_RS03860	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DDJ96_RS03870	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DDJ96_RS03875	COG3933	PFAM sigma-54 factor interaction domain-containing protein
DDJ96_RS03875	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DDJ96_RS03880	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDJ96_RS03880	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDJ96_RS03890	COG3715	PTS system
DDJ96_RS03895	COG3716	PTS system mannose fructose sorbose family IID component
DDJ96_RS03905	COG2261	transglycosylase associated protein
DDJ96_RS03910	COG0006	proline dipeptidase activity
DDJ96_RS03915	COG1302	Protein conserved in bacteria
DDJ96_RS03920	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DDJ96_RS03925	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DDJ96_RS03930	COG1570	exodeoxyribonuclease VII activity
DDJ96_RS03935	COG1722	exodeoxyribonuclease VII activity
DDJ96_RS03940	COG0142	geranyltranstransferase activity
DDJ96_RS03945	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DDJ96_RS03950	COG1438	arginine binding
DDJ96_RS03955	COG0497	DNA recombination
DDJ96_RS04010	COG0768	penicillin binding
DDJ96_RS04045	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DDJ96_RS04050	COG1799	cell septum assembly
DDJ96_RS04060	COG2302	S4 RNA-binding domain
DDJ96_RS04065	COG3599	regulation of cell shape
DDJ96_RS04070	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DDJ96_RS04080	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DDJ96_RS04085	COG1321	iron dependent repressor
DDJ96_RS04085	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DDJ96_RS04100	COG0673	inositol 2-dehydrogenase activity
DDJ96_RS04110	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DDJ96_RS04110	COG3933	PFAM sigma-54 factor interaction domain-containing protein
DDJ96_RS04115	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DDJ96_RS04125	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DDJ96_RS04160	COG2309	aminopeptidase activity
DDJ96_RS04170	COG0716	FMN binding
DDJ96_RS04175	COG0024	Methionine aminopeptidase
DDJ96_RS04180	COG1295	ribonuclease BN
DDJ96_RS04185	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DDJ96_RS04200	COG0463	Glycosyl transferase, family 2
DDJ96_RS04205	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DDJ96_RS04215	COG1088	dTDP-glucose 4,6-dehydratase activity
DDJ96_RS04220	COG1091	dTDP-4-dehydrorhamnose reductase activity
DDJ96_RS04235	COG1682	transport, permease protein
DDJ96_RS04240	COG1134	teichoic acid transport
DDJ96_RS04250	COG1216	Glycosyl transferase, family 2
DDJ96_RS04250	COG0438	transferase activity, transferring glycosyl groups
DDJ96_RS04255	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DDJ96_RS04260	COG1216	Glycosyl transferase, family 2
DDJ96_RS04265	COG3475	LICD family
DDJ96_RS04280	COG1442	glycosyl transferase family 8
DDJ96_RS04280	COG1216	Glycosyl transferase, family 2
DDJ96_RS04290	COG3475	LICD family
DDJ96_RS04315	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DDJ96_RS04320	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DDJ96_RS04330	COG4585	Histidine kinase
DDJ96_RS04335	COG2197	response regulator
DDJ96_RS04345	COG2239	Acts as a magnesium transporter
DDJ96_RS04350	COG0569	domain protein
DDJ96_RS04355	COG4841	protein insertion into membrane
DDJ96_RS04370	COG2246	polysaccharide biosynthetic process
DDJ96_RS04375	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DDJ96_RS04380	COG1278	Cold shock
DDJ96_RS04405	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DDJ96_RS04410	COG1316	TRANSCRIPTIONal
DDJ96_RS04420	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
DDJ96_RS04430	COG3397	chitin binding
DDJ96_RS04440	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DDJ96_RS04445	COG2137	regulation of response to DNA damage stimulus
DDJ96_RS04450	COG1194	a g-specific adenine glycosylase
DDJ96_RS04455	COG3557	Belongs to the UPF0374 family
DDJ96_RS04465	COG0628	permease
DDJ96_RS04470	COG1253	flavin adenine dinucleotide binding
DDJ96_RS04475	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DDJ96_RS04490	COG0542	response to heat
DDJ96_RS04495	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDJ96_RS04500	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DDJ96_RS04510	COG0438	transferase activity, transferring glycosyl groups
DDJ96_RS04515	COG2084	Dehydrogenase
DDJ96_RS04520	COG4703	Protein of unknown function (DUF1797)
DDJ96_RS04530	COG1846	Transcriptional regulator
DDJ96_RS04535	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DDJ96_RS04545	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DDJ96_RS04560	COG0511	ligase activity, forming carbon-carbon bonds
DDJ96_RS04565	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DDJ96_RS04570	COG0439	Biotin carboxylase
DDJ96_RS04575	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DDJ96_RS04580	COG0825	malonyl-CoA metabolic process
DDJ96_RS04610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DDJ96_RS04615	COG0765	amino acid transport
DDJ96_RS04620	COG1126	abc transporter atp-binding protein
DDJ96_RS04625	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
DDJ96_RS04630	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DDJ96_RS04635	COG1534	Rna-binding protein
DDJ96_RS04640	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DDJ96_RS04645	COG1713	HD superfamily hydrolase involved in NAD metabolism
DDJ96_RS04650	COG0799	negative regulation of ribosome biogenesis
DDJ96_RS04655	COG2226	methyltransferase
DDJ96_RS04660	COG1323	Belongs to the UPF0348 family
DDJ96_RS04665	COG0217	transcriptional regulatory protein
DDJ96_RS04680	COG3973	AAA domain
DDJ96_RS04685	COG2217	Heavy metal translocating P-type atpase
DDJ96_RS04690	COG1942	4-Oxalocrotonate Tautomerase
DDJ96_RS04695	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DDJ96_RS04710	COG1737	Transcriptional regulator
DDJ96_RS04715	COG0768	penicillin binding
DDJ96_RS04720	COG0561	phosphatase activity
DDJ96_RS04725	COG2252	PERMEase
DDJ96_RS04730	COG2814	Major facilitator Superfamily
DDJ96_RS04740	COG0587	DNA-directed DNA polymerase activity
DDJ96_RS04745	COG0205	6-phosphofructokinase activity
DDJ96_RS04755	COG0583	DNA-binding transcription factor activity
DDJ96_RS04770	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DDJ96_RS04775	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DDJ96_RS04780	COG0745	RESPONSE REGULATOR receiver
DDJ96_RS04785	COG5002	protein histidine kinase activity
DDJ96_RS04900	COG1609	Transcriptional regulator
DDJ96_RS04925	COG1175	transmembrane transport
DDJ96_RS04930	COG0395	ABC-type sugar transport system, permease component
DDJ96_RS04980	COG0400	carboxylic ester hydrolase activity
DDJ96_RS04985	COG0346	lactoylglutathione lyase activity
DDJ96_RS04990	COG2188	Transcriptional regulator
DDJ96_RS04995	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DDJ96_RS05000	COG2723	6-phospho-beta-galactosidase activity
DDJ96_RS05005	COG0589	response to stress
DDJ96_RS05010	COG0351	phosphomethylpyrimidine kinase
DDJ96_RS05015	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DDJ96_RS05020	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DDJ96_RS05030	COG3425	synthase
DDJ96_RS05035	COG0183	Belongs to the thiolase family
DDJ96_RS05050	COG1316	TRANSCRIPTIONal
DDJ96_RS05065	COG0656	L-ascorbic acid biosynthetic process
DDJ96_RS05095	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DDJ96_RS05095	COG0392	lysyltransferase activity
DDJ96_RS05105	COG0741	lytic transglycosylase activity
DDJ96_RS05115	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DDJ96_RS05120	COG0358	DNA primase activity
DDJ96_RS05125	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DDJ96_RS05135	COG2996	Protein conserved in bacteria
DDJ96_RS05140	COG0735	belongs to the Fur family
DDJ96_RS05145	COG4974	Belongs to the 'phage' integrase family
DDJ96_RS05155	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DDJ96_RS05160	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DDJ96_RS05165	COG1187	pseudouridine synthase activity
DDJ96_RS05170	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DDJ96_RS05175	COG1288	antiporter activity
DDJ96_RS05180	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DDJ96_RS05190	COG1141	Ferredoxin
DDJ96_RS05200	COG0514	ATP-dependent DNA helicase (RecQ)
DDJ96_RS05210	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DDJ96_RS05215	COG0539	negative regulation of cytoplasmic translation
DDJ96_RS05220	COG1160	GTP binding
DDJ96_RS05225	COG0776	regulation of translation
DDJ96_RS05235	COG0457	Tetratricopeptide repeat
DDJ96_RS05240	COG5582	Belongs to the UPF0302 family
DDJ96_RS05245	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DDJ96_RS05250	COG1694	Mazg nucleotide pyrophosphohydrolase
DDJ96_RS05255	COG0617	tRNA 3'-terminal CCA addition
DDJ96_RS05270	COG0025	NhaP-type Na H and K H
DDJ96_RS05275	COG0488	(ABC) transporter
DDJ96_RS05280	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DDJ96_RS05290	COG1307	EDD domain protein, DegV family
DDJ96_RS05295	COG2755	lipolytic protein G-D-S-L family
DDJ96_RS05300	COG4698	Protein conserved in bacteria
DDJ96_RS05310	COG4479	Belongs to the UPF0346 family
DDJ96_RS05315	COG0681	Belongs to the peptidase S26 family
DDJ96_RS05345	COG0758	DNA mediated transformation
DDJ96_RS05350	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DDJ96_RS05355	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DDJ96_RS05360	COG4974	Belongs to the 'phage' integrase family
DDJ96_RS05365	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DDJ96_RS05370	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DDJ96_RS05375	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
DDJ96_RS05385	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DDJ96_RS05390	COG1832	CoA-binding protein
DDJ96_RS05395	COG0187	DNA topoisomerase II activity
DDJ96_RS05405	COG1882	Formate acetyltransferase
DDJ96_RS05410	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DDJ96_RS05415	COG1227	inorganic diphosphatase activity
DDJ96_RS05430	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
DDJ96_RS05440	COG1073	alpha beta
DDJ96_RS05445	COG1609	Transcriptional regulator
DDJ96_RS05455	COG0604	alcohol dehydrogenase
DDJ96_RS05460	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DDJ96_RS05475	COG0517	IMP dehydrogenase activity
DDJ96_RS05475	COG1125	glycine betaine transport
DDJ96_RS05505	COG3942	CHAP domain
DDJ96_RS05505	COG1388	LysM domain
DDJ96_RS05525	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DDJ96_RS05540	COG1396	sequence-specific DNA binding
DDJ96_RS05785	COG0741	lytic transglycosylase activity
DDJ96_RS05785	COG1196	nuclear chromosome segregation
DDJ96_RS05785	COG0739	heme binding
DDJ96_RS05815	COG4824	toxin secretion phage lysis holin
DDJ96_RS05860	COG0436	Aminotransferase
DDJ96_RS05875	COG0789	Transcriptional regulator
DDJ96_RS05880	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DDJ96_RS05900	COG2268	Band 7 protein
DDJ96_RS05910	COG4129	membrane
DDJ96_RS05925	COG1876	peptidase activity
DDJ96_RS05930	COG1705	Flagellar rod assembly protein muramidase FlgJ
DDJ96_RS05940	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DDJ96_RS05945	COG2233	PERMEase
DDJ96_RS05955	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DDJ96_RS05960	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DDJ96_RS05965	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DDJ96_RS05975	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DDJ96_RS05980	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DDJ96_RS05985	COG0047	phosphoribosylformylglycinamidine synthase activity
DDJ96_RS05990	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DDJ96_RS06000	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DDJ96_RS06005	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DDJ96_RS06010	COG0138	bifunctional purine biosynthesis protein purh
DDJ96_RS06015	COG0151	Belongs to the GarS family
DDJ96_RS06020	COG4989	oxidoreductase activity
DDJ96_RS06030	COG0516	GMP reductase activity
DDJ96_RS06035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DDJ96_RS06060	COG4476	Belongs to the UPF0223 family
DDJ96_RS06065	COG0483	inositol monophosphate 1-phosphatase activity
DDJ96_RS06075	COG1217	gtp-binding protein TYPA
DDJ96_RS06085	COG0514	ATP-dependent DNA helicase (RecQ)
DDJ96_RS06090	COG4838	Belongs to the UPF0358 family
DDJ96_RS06095	COG0772	Belongs to the SEDS family
DDJ96_RS06100	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
DDJ96_RS06115	COG4471	UPF0298 protein
DDJ96_RS06120	COG0742	ribosomal rna small subunit methyltransferase
DDJ96_RS06125	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DDJ96_RS06130	COG3480	Lon protease (S16) C-terminal proteolytic domain
DDJ96_RS06140	COG1596	polysaccharide export
DDJ96_RS06140	COG1555	photosystem II stabilization
DDJ96_RS06145	COG2131	deaminase
DDJ96_RS06150	COG0658	competence protein
DDJ96_RS06150	COG2333	competence protein COMEC
DDJ96_RS06155	COG1466	dna polymerase III delta subunit
DDJ96_RS06160	COG0268	Binds directly to 16S ribosomal RNA
DDJ96_RS06170	COG2707	UPF0756 membrane protein
DDJ96_RS06205	COG1695	Transcriptional regulator
DDJ96_RS06210	COG0488	(ABC) transporter
DDJ96_RS06215	COG1968	undecaprenyl-diphosphatase activity
DDJ96_RS06230	COG1199	ATP-dependent helicase activity
DDJ96_RS06235	COG1666	GTP binding
DDJ96_RS06240	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DDJ96_RS06245	COG2151	metal-sulfur cluster biosynthetic enzyme
DDJ96_RS06280	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DDJ96_RS06290	COG3942	CHAP domain
DDJ96_RS06290	COG1388	LysM domain
DDJ96_RS06330	COG4990	cell redox homeostasis
DDJ96_RS06350	COG3104	oligopeptide transport
DDJ96_RS06355	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
DDJ96_RS06360	COG1074	ATP-dependent DNA helicase activity
DDJ96_RS06365	COG1733	regulation of RNA biosynthetic process
DDJ96_RS06370	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DDJ96_RS06375	COG0072	phenylalanine-tRNA ligase activity
DDJ96_RS06375	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DDJ96_RS06395	COG1126	abc transporter atp-binding protein
DDJ96_RS06400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DDJ96_RS06405	COG0765	amino acid transport
DDJ96_RS06410	COG0765	amino acid transport
DDJ96_RS06415	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DDJ96_RS06430	COG0517	IMP dehydrogenase activity
DDJ96_RS06435	COG0668	transmembrane transport
DDJ96_RS06440	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DDJ96_RS06445	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DDJ96_RS06450	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DDJ96_RS06455	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DDJ96_RS06470	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DDJ96_RS06480	COG1234	tRNA 3'-trailer cleavage
DDJ96_RS06485	COG0300	oxidoreductase activity
DDJ96_RS06495	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DDJ96_RS06495	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DDJ96_RS06500	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DDJ96_RS06510	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DDJ96_RS06525	COG1705	Flagellar rod assembly protein muramidase FlgJ
DDJ96_RS06525	COG1388	LysM domain
DDJ96_RS06535	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DDJ96_RS06540	COG0735	belongs to the Fur family
DDJ96_RS06545	COG0446	pyridine nucleotide-disulphide oxidoreductase
DDJ96_RS06555	COG3935	DnaD domain protein
DDJ96_RS06560	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DDJ96_RS06575	COG3397	chitin binding
DDJ96_RS06610	COG0791	NLP P60 protein
DDJ96_RS06610	COG0741	lytic transglycosylase activity
DDJ96_RS06665	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DDJ96_RS06670	COG3331	DNA recombination
DDJ96_RS06675	COG4474	Belongs to the UPF0398 family
DDJ96_RS06680	COG3599	regulation of cell shape
DDJ96_RS06690	COG0116	Belongs to the methyltransferase superfamily
DDJ96_RS06700	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
DDJ96_RS06705	COG1418	mRNA catabolic process
DDJ96_RS06720	COG0513	Belongs to the DEAD box helicase family
DDJ96_RS06735	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DDJ96_RS06740	COG4684	Psort location CytoplasmicMembrane, score
DDJ96_RS06750	COG0328	RNA-DNA hybrid ribonuclease activity
DDJ96_RS06760	COG1278	Cold shock
DDJ96_RS06765	COG2759	Belongs to the formate--tetrahydrofolate ligase family
DDJ96_RS06805	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DDJ96_RS06810	COG0564	pseudouridine synthase activity
DDJ96_RS06820	COG2233	PERMEase
DDJ96_RS06825	COG0540	Belongs to the ATCase OTCase family
DDJ96_RS06830	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DDJ96_RS06835	COG0505	Belongs to the CarA family
DDJ96_RS06840	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DDJ96_RS06845	COG0543	2 iron, 2 sulfur cluster binding
DDJ96_RS06850	COG0167	dihydroorotate dehydrogenase activity
DDJ96_RS06855	COG0284	orotidine-5'-phosphate decarboxylase activity
DDJ96_RS06875	COG0583	DNA-binding transcription factor activity
DDJ96_RS06885	COG1293	RNA-binding protein homologous to eukaryotic snRNP
DDJ96_RS06900	COG4120	Belongs to the binding-protein-dependent transport system permease family
DDJ96_RS06905	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
DDJ96_RS07005	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DDJ96_RS07015	COG0456	acetyltransferase
DDJ96_RS07030	COG0039	L-malate dehydrogenase activity
DDJ96_RS07055	COG1874	Beta-galactosidase
DDJ96_RS07070	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DDJ96_RS07075	COG1609	Transcriptional regulator
DDJ96_RS07080	COG0673	inositol 2-dehydrogenase activity
DDJ96_RS07085	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DDJ96_RS07090	COG0406	alpha-ribazole phosphatase activity
DDJ96_RS07125	COG0745	RESPONSE REGULATOR receiver
DDJ96_RS07130	COG5002	protein histidine kinase activity
DDJ96_RS07135	COG4974	Belongs to the 'phage' integrase family
DDJ96_RS07145	COG0351	phosphomethylpyrimidine kinase
DDJ96_RS07150	COG4720	Psort location CytoplasmicMembrane, score
DDJ96_RS07155	COG4475	Protein of unknown function (DUF436)
DDJ96_RS07160	COG0366	Alpha amylase catalytic
DDJ96_RS07175	COG1307	EDD domain protein, DegV family
DDJ96_RS07180	COG2244	polysaccharide biosynthetic process
DDJ96_RS07225	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DDJ96_RS07230	COG0194	GDP metabolic process
DDJ96_RS07255	COG0167	dihydroorotate dehydrogenase activity
DDJ96_RS07265	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DDJ96_RS07275	COG3833	ABC-type maltose transport systems, permease component
DDJ96_RS07280	COG1175	transmembrane transport
DDJ96_RS07285	COG2182	Extracellular solute-binding protein
DDJ96_RS07290	COG0366	Alpha amylase catalytic
DDJ96_RS07295	COG4948	Mandelate Racemase Muconate Lactonizing
DDJ96_RS07305	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
DDJ96_RS07310	COG1169	isochorismate synthase
DDJ96_RS07315	COG0318	PFAM AMP-dependent synthetase and ligase
DDJ96_RS07320	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DDJ96_RS07375	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DDJ96_RS07380	COG1764	response to oxidative stress
DDJ96_RS07385	COG1846	Transcriptional regulator
DDJ96_RS07390	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
DDJ96_RS07425	COG0768	penicillin binding
DDJ96_RS07435	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DDJ96_RS07450	COG0737	Belongs to the 5'-nucleotidase family
DDJ96_RS07455	COG1653	transport
DDJ96_RS07470	COG1175	transmembrane transport
DDJ96_RS07475	COG3842	ATPase activity
DDJ96_RS07480	COG2261	transglycosylase associated protein
DDJ96_RS07505	COG4512	PFAM Accessory gene regulator B
DDJ96_RS07525	COG3655	Transcriptional regulator
DDJ96_RS07555	COG2261	transglycosylase associated protein
DDJ96_RS07575	COG1028	Short-chain dehydrogenase reductase Sdr
DDJ96_RS07590	COG1442	glycosyl transferase family 8
DDJ96_RS07595	COG1442	glycosyl transferase family 8
DDJ96_RS07600	COG0561	phosphatase activity
DDJ96_RS07615	COG1476	TRANSCRIPTIONal
DDJ96_RS07625	COG1278	Cold shock
DDJ96_RS07630	COG0655	NAD(P)H dehydrogenase (quinone) activity
DDJ96_RS07645	COG0789	Transcriptional regulator
DDJ96_RS07660	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DDJ96_RS07665	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DDJ96_RS07680	COG1136	(ABC) transporter
DDJ96_RS07690	COG0481	GTPase activity
DDJ96_RS07710	COG4975	Glucose uptake
DDJ96_RS07715	COG0383	alpha-mannosidase activity
DDJ96_RS07720	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDJ96_RS07725	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDJ96_RS07730	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDJ96_RS07735	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDJ96_RS07735	COG3711	transcriptional antiterminator
DDJ96_RS07740	COG0542	response to heat
DDJ96_RS07750	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DDJ96_RS07755	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DDJ96_RS07760	COG1446	asparaginase
DDJ96_RS07765	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DDJ96_RS07770	COG2188	Transcriptional regulator
DDJ96_RS07790	COG1597	lipid kinase activity
DDJ96_RS07795	COG2195	Cleaves the N-terminal amino acid of tripeptides
DDJ96_RS07800	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DDJ96_RS07805	COG2384	SAM-dependent methyltransferase
DDJ96_RS07815	COG1484	DNA-dependent DNA replication
DDJ96_RS07825	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DDJ96_RS07835	COG0237	dephospho-CoA kinase activity
DDJ96_RS07840	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DDJ96_RS07845	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DDJ96_RS07845	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DDJ96_RS07860	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DDJ96_RS07865	COG1434	Gram-negative-bacterium-type cell wall biogenesis
DDJ96_RS07870	COG3091	SprT-like family
DDJ96_RS07875	COG2183	response to ionizing radiation
DDJ96_RS07880	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DDJ96_RS07885	COG1054	Belongs to the UPF0176 family
DDJ96_RS07945	COG1823	symporter activity
DDJ96_RS08000	COG4753	response regulator
DDJ96_RS08000	COG2207	Transcriptional regulator
DDJ96_RS08005	COG2972	Histidine kinase
DDJ96_RS08010	COG3250	beta-galactosidase activity
DDJ96_RS08025	COG1609	Transcriptional regulator
DDJ96_RS08030	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DDJ96_RS08045	COG1132	(ABC) transporter
DDJ96_RS08070	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DDJ96_RS08075	COG1597	lipid kinase activity
DDJ96_RS08080	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DDJ96_RS08085	COG0154	amidase activity
DDJ96_RS08090	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DDJ96_RS08095	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DDJ96_RS08100	COG0210	DNA helicase
DDJ96_RS08105	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDJ96_RS08105	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDJ96_RS08105	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDJ96_RS08110	COG1105	Belongs to the carbohydrate kinase PfkB family
DDJ96_RS08115	COG1349	DNA-binding transcription factor activity
DDJ96_RS08125	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DDJ96_RS08130	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DDJ96_RS08135	COG0544	peptidyl-prolyl cis-trans isomerase activity
DDJ96_RS08145	COG1714	RDD family
DDJ96_RS08160	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DDJ96_RS08230	COG1481	regulation of sporulation
DDJ96_RS08235	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DDJ96_RS08240	COG1660	Displays ATPase and GTPase activities
DDJ96_RS08245	COG1794	racemase activity, acting on amino acids and derivatives
DDJ96_RS08255	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DDJ96_RS08260	COG0556	nucleotide-excision repair
DDJ96_RS08265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DDJ96_RS08280	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DDJ96_RS08280	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DDJ96_RS08285	COG1447	Phosphotransferase system cellobiose-specific component IIA
DDJ96_RS08290	COG2723	6-phospho-beta-galactosidase activity
DDJ96_RS08295	COG1349	DNA-binding transcription factor activity
DDJ96_RS08300	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DDJ96_RS08305	COG0484	heat shock protein binding
DDJ96_RS08310	COG0443	Heat shock 70 kDa protein
DDJ96_RS08315	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DDJ96_RS08320	COG1420	regulation of RNA biosynthetic process
DDJ96_RS08325	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DDJ96_RS08330	COG2801	Transposase and inactivated derivatives
DDJ96_RS08335	COG2801	Transposase and inactivated derivatives
DDJ96_RS08360	COG4658	electron transport chain
DDJ96_RS08365	COG4656	Part of a membrane complex involved in electron transport
DDJ96_RS08370	COG0205	6-phosphofructokinase activity
DDJ96_RS08385	COG4975	Glucose uptake
DDJ96_RS08395	COG0196	riboflavin kinase activity
DDJ96_RS08400	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DDJ96_RS08405	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DDJ96_RS08420	COG2740	Nucleic-acid-binding protein implicated in transcription termination
DDJ96_RS08425	COG0195	Participates in both transcription termination and antitermination
DDJ96_RS08430	COG0779	Required for maturation of 30S ribosomal subunits
DDJ96_RS08435	COG2176	DNA-directed DNA polymerase activity
DDJ96_RS08440	COG0442	prolyl-tRNA aminoacylation
DDJ96_RS08445	COG0750	zinc metalloprotease
DDJ96_RS08450	COG4589	Belongs to the CDS family
DDJ96_RS08455	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DDJ96_RS08460	COG0233	cytoplasmic translational termination
DDJ96_RS08465	COG0528	UMP kinase activity
DDJ96_RS08470	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DDJ96_RS08475	COG0052	Belongs to the universal ribosomal protein uS2 family
DDJ96_RS08480	COG1438	arginine binding
DDJ96_RS08495	COG0018	arginyl-trna synthetase
DDJ96_RS08505	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DDJ96_RS08510	COG2235	arginine
DDJ96_RS08525	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DDJ96_RS08530	COG1215	transferase activity, transferring glycosyl groups
DDJ96_RS08540	COG0438	transferase activity, transferring glycosyl groups
DDJ96_RS08545	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DDJ96_RS08550	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DDJ96_RS08570	COG0489	protein tyrosine kinase activity
DDJ96_RS08575	COG3944	biosynthesis protein
DDJ96_RS08595	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DDJ96_RS08610	COG1214	PFAM Peptidase M22, glycoprotease
DDJ96_RS08615	COG1609	Transcriptional regulator
DDJ96_RS08620	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
DDJ96_RS08625	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DDJ96_RS08640	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DDJ96_RS08645	COG1940	carbohydrate kinase activity
DDJ96_RS08660	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DDJ96_RS08685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDJ96_RS08690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDJ96_RS08695	COG1120	ATPase activity
DDJ96_RS08705	COG0745	RESPONSE REGULATOR receiver
DDJ96_RS08710	COG2205	protein histidine kinase activity
DDJ96_RS08715	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DDJ96_RS08720	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DDJ96_RS08725	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DDJ96_RS08735	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DDJ96_RS08740	COG4876	unkown
DDJ96_RS08745	COG0367	asparagine synthase
DDJ96_RS08765	COG1309	transcriptional regulator
DDJ96_RS08780	COG0398	Pfam SNARE associated Golgi protein
DDJ96_RS08785	COG0584	glycerophosphoryl diester phosphodiesterase
DDJ96_RS08795	COG1396	sequence-specific DNA binding
DDJ96_RS08810	COG1278	Cold shock
DDJ96_RS08825	COG1278	Cold shock
DDJ96_RS08835	COG0166	Belongs to the GPI family
DDJ96_RS08840	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DDJ96_RS08845	COG2081	HI0933 family
DDJ96_RS08850	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DDJ96_RS08855	COG0710	3-dehydroquinate dehydratase activity
DDJ96_RS08860	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DDJ96_RS08865	COG1368	sulfuric ester hydrolase activity
DDJ96_RS08880	COG5002	protein histidine kinase activity
DDJ96_RS08880	COG3850	Histidine kinase
DDJ96_RS08885	COG0745	RESPONSE REGULATOR receiver
DDJ96_RS08920	COG3052	prosthetic group binding
DDJ96_RS08925	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
DDJ96_RS08935	COG0511	ligase activity, forming carbon-carbon bonds
DDJ96_RS08945	COG2851	Citrate transporter
DDJ96_RS08950	COG2188	Transcriptional regulator
DDJ96_RS08955	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
DDJ96_RS08960	COG0745	RESPONSE REGULATOR receiver
DDJ96_RS08970	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
DDJ96_RS08975	COG0778	Nitroreductase
DDJ96_RS08980	COG1846	Transcriptional regulator
DDJ96_RS08990	COG1956	GAF domain-containing protein
DDJ96_RS08995	COG3527	Alpha-acetolactate decarboxylase
DDJ96_RS09030	COG0028	Belongs to the TPP enzyme family
DDJ96_RS09035	COG1247	-acetyltransferase
DDJ96_RS09045	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DDJ96_RS09050	COG3064	Membrane
DDJ96_RS09050	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DDJ96_RS09050	COG3583	domain protein
DDJ96_RS09060	COG1349	DNA-binding transcription factor activity
DDJ96_RS09065	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DDJ96_RS09095	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DDJ96_RS09165	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
DDJ96_RS09170	COG2160	L-arabinose isomerase activity
DDJ96_RS09185	COG1609	Transcriptional regulator
DDJ96_RS09195	COG4214	carbohydrate transport
DDJ96_RS09205	COG4213	ABC transporter substrate-binding protein
DDJ96_RS09210	COG1879	ABC-type sugar transport system periplasmic component
DDJ96_RS09215	COG2972	Histidine kinase
DDJ96_RS09220	COG4753	response regulator
DDJ96_RS09220	COG2207	Transcriptional regulator
DDJ96_RS09245	COG0446	pyridine nucleotide-disulphide oxidoreductase
DDJ96_RS09260	COG3732	PTS system glucitol sorbitol-specific
DDJ96_RS09265	COG3730	PTS system glucitol sorbitol-specific
DDJ96_RS09295	COG0352	thiamine-phosphate diphosphorylase activity
DDJ96_RS09295	COG0351	phosphomethylpyrimidine kinase
DDJ96_RS09300	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DDJ96_RS09310	COG0335	large ribosomal subunit rRNA binding
DDJ96_RS09315	COG0336	Belongs to the RNA methyltransferase TrmD family
DDJ96_RS09320	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DDJ96_RS09330	COG1837	Belongs to the UPF0109 family
DDJ96_RS09335	COG0228	four-way junction DNA binding
DDJ96_RS09340	COG0431	NADPH-dependent FMN reductase
DDJ96_RS09345	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DDJ96_RS09350	COG0519	Catalyzes the synthesis of GMP from XMP
DDJ96_RS09355	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DDJ96_RS09360	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
DDJ96_RS09365	COG1683	Conserved Protein
DDJ96_RS09370	COG0745	RESPONSE REGULATOR receiver
DDJ96_RS09375	COG5002	protein histidine kinase activity
DDJ96_RS09380	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DDJ96_RS09385	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DDJ96_RS09410	COG2217	Heavy metal translocating P-type atpase
DDJ96_RS09415	COG2217	Heavy metal translocating P-type atpase
DDJ96_RS09420	COG2608	mercury ion transmembrane transporter activity
DDJ96_RS09425	COG3682	Transcriptional regulator
DDJ96_RS09435	COG0531	amino acid
DDJ96_RS09440	COG2217	Heavy metal translocating P-type atpase
DDJ96_RS09470	COG0017	Asparaginyl-tRNA synthetase
DDJ96_RS09475	COG0436	Aminotransferase
DDJ96_RS09485	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DDJ96_RS09485	COG1199	ATP-dependent helicase activity
DDJ96_RS09490	COG1278	Cold shock
DDJ96_RS09500	COG1686	Belongs to the peptidase S11 family
DDJ96_RS09510	COG0038	chloride channel
DDJ96_RS09525	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DDJ96_RS09530	COG1254	Belongs to the acylphosphatase family
DDJ96_RS09535	COG0706	membrane insertase activity
DDJ96_RS09540	COG0751	glycine-tRNA ligase activity
DDJ96_RS09545	COG0752	glycyl-tRNA synthetase alpha subunit
DDJ96_RS09550	COG1381	Involved in DNA repair and RecF pathway recombination
DDJ96_RS09555	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DDJ96_RS09560	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DDJ96_RS09565	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DDJ96_RS09575	COG1702	phosphate starvation-inducible protein PhoH
DDJ96_RS09580	COG1610	YqeY-like protein
DDJ96_RS09585	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DDJ96_RS09590	COG0735	belongs to the Fur family
DDJ96_RS09595	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DDJ96_RS09605	COG0640	Transcriptional regulator
DDJ96_RS09610	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DDJ96_RS09615	COG0492	ferredoxin-NADP+ reductase activity
DDJ96_RS09620	COG2723	6-phospho-beta-galactosidase activity
DDJ96_RS09625	COG1486	melibiose metabolic process
DDJ96_RS09630	COG1737	Transcriptional regulator
DDJ96_RS09635	COG2190	(PTS) system
DDJ96_RS09635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDJ96_RS09635	COG1263	PTS System
DDJ96_RS09640	COG3711	transcriptional antiterminator
DDJ96_RS09645	COG1132	(ABC) transporter
DDJ96_RS09650	COG1132	(ABC) transporter
DDJ96_RS09655	COG3763	UPF0154 protein
DDJ96_RS09660	COG1914	H( )-stimulated, divalent metal cation uptake system
DDJ96_RS09670	COG0656	L-ascorbic acid biosynthetic process
DDJ96_RS09675	COG0789	Transcriptional regulator
DDJ96_RS09680	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DDJ96_RS09685	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DDJ96_RS09690	COG1609	Transcriptional regulator
DDJ96_RS09695	COG0006	proline dipeptidase activity
DDJ96_RS09705	COG4980	gas vesicle protein
DDJ96_RS09715	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DDJ96_RS09720	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DDJ96_RS09725	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DDJ96_RS09730	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DDJ96_RS09760	COG0704	Plays a role in the regulation of phosphate uptake
DDJ96_RS09765	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DDJ96_RS09770	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DDJ96_RS09775	COG0581	inorganic phosphate transmembrane transporter activity
DDJ96_RS09780	COG0573	inorganic phosphate transmembrane transporter activity
DDJ96_RS09785	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DDJ96_RS09790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DDJ96_RS09795	COG2177	Part of the ABC transporter FtsEX involved in
DDJ96_RS09800	COG2884	Cell division ATP-binding protein ftsE
DDJ96_RS09810	COG0653	protein targeting
DDJ96_RS09820	COG1040	competence protein
DDJ96_RS09825	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DDJ96_RS09835	COG1739	Uncharacterized protein family UPF0029
DDJ96_RS09840	COG2188	Transcriptional regulator
DDJ96_RS09870	COG1940	carbohydrate kinase activity
DDJ96_RS09875	COG0456	acetyltransferase
DDJ96_RS09890	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DDJ96_RS09900	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DDJ96_RS09905	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DDJ96_RS09910	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DDJ96_RS09915	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DDJ96_RS09920	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DDJ96_RS09925	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DDJ96_RS09930	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DDJ96_RS09935	COG0356	it plays a direct role in the translocation of protons across the membrane
DDJ96_RS09940	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DDJ96_RS09945	COG0557	exoribonuclease II activity
DDJ96_RS09955	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DDJ96_RS09960	COG2388	GCN5-related N-acetyl-transferase
DDJ96_RS09980	COG0110	maltose O-acetyltransferase activity
DDJ96_RS10035	COG0149	triose-phosphate isomerase activity
DDJ96_RS10040	COG0126	phosphoglycerate kinase activity
DDJ96_RS10055	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DDJ96_RS10085	COG0095	Lipoate-protein ligase
DDJ96_RS10090	COG1078	dGTPase activity
DDJ96_RS10095	COG0561	phosphatase activity
DDJ96_RS10100	COG0494	nUDIX hydrolase
DDJ96_RS10105	COG0346	lactoylglutathione lyase activity
DDJ96_RS10110	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DDJ96_RS10115	COG1394	ATPase activity, coupled to movement of substances
DDJ96_RS10120	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
DDJ96_RS10125	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
DDJ96_RS10130	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
DDJ96_RS10135	COG1527	subunit (C
DDJ96_RS10140	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
DDJ96_RS10145	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DDJ96_RS10150	COG1269	ATP hydrolysis coupled proton transport
DDJ96_RS10160	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DDJ96_RS10165	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
DDJ96_RS10175	COG4152	abc transporter atp-binding protein
DDJ96_RS10180	COG0322	excinuclease ABC activity
DDJ96_RS10185	COG3118	belongs to the thioredoxin family
DDJ96_RS10190	COG1193	negative regulation of DNA recombination
DDJ96_RS10205	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DDJ96_RS10210	COG4991	sh3 domain protein
DDJ96_RS10210	COG3103	Sh3 type 3 domain protein
DDJ96_RS10210	COG0860	N-Acetylmuramoyl-L-alanine amidase
DDJ96_RS10225	COG1309	transcriptional regulator
DDJ96_RS10230	COG1136	(ABC) transporter
DDJ96_RS10240	COG3623	hexulose-6-phosphate isomerase
DDJ96_RS10275	COG1304	FMN binding
DDJ96_RS10285	COG2423	ornithine cyclodeaminase activity
DDJ96_RS10290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DDJ96_RS10295	COG0281	malic enzyme
DDJ96_RS10315	COG3906	Belongs to the UPF0473 family
DDJ96_RS10320	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DDJ96_RS10325	COG4472	Bacterial protein of unknown function (DUF965)
DDJ96_RS10340	COG1309	transcriptional regulator
DDJ96_RS10355	COG3689	TIGRFAM TIGR03943 family protein
DDJ96_RS10360	COG0701	Predicted permease
DDJ96_RS10375	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DDJ96_RS10380	COG0488	(ABC) transporter
DDJ96_RS10385	COG3254	rhamnose metabolic process
DDJ96_RS10405	COG1131	(ABC) transporter
DDJ96_RS10410	COG4585	Histidine kinase
DDJ96_RS10415	COG2197	response regulator
DDJ96_RS10500	COG0433	COG0433 Predicted ATPase
DDJ96_RS10530	COG2946	Replication initiation factor
DDJ96_RS10540	COG1674	ftsk spoiiie
DDJ96_RS10600	COG1396	sequence-specific DNA binding
DDJ96_RS10605	COG2856	Zn peptidase
DDJ96_RS10630	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DDJ96_RS10635	COG1177	transmembrane transport
DDJ96_RS10640	COG1176	ABC-type spermidine putrescine transport system, permease component I
DDJ96_RS10645	COG3842	ATPase activity
DDJ96_RS10655	COG0604	alcohol dehydrogenase
DDJ96_RS10660	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DDJ96_RS10665	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DDJ96_RS10670	COG4684	Psort location CytoplasmicMembrane, score
DDJ96_RS10680	COG0604	alcohol dehydrogenase
DDJ96_RS10680	COG3321	synthase
DDJ96_RS10680	COG1028	Short-chain dehydrogenase reductase Sdr
DDJ96_RS10685	COG1053	succinate dehydrogenase
DDJ96_RS10700	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DDJ96_RS10710	COG0708	Exodeoxyribonuclease III
DDJ96_RS10725	COG0802	atpase or kinase
DDJ96_RS10730	COG0280	phosphate acetyltransferase
DDJ96_RS10735	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DDJ96_RS10740	COG0561	phosphatase activity
DDJ96_RS10770	COG0346	lactoylglutathione lyase activity
DDJ96_RS10785	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DDJ96_RS10815	COG1263	PTS System
DDJ96_RS10815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDJ96_RS10820	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DDJ96_RS10865	COG0588	phosphoglycerate mutase activity
DDJ96_RS10870	COG0488	(ABC) transporter
DDJ96_RS10875	COG1929	Belongs to the glycerate kinase type-1 family
DDJ96_RS10885	COG1113	amino acid transport
DDJ96_RS10890	COG1757	Na H antiporter
DDJ96_RS10895	COG1473	amidohydrolase
DDJ96_RS10900	COG1464	Belongs to the NlpA lipoprotein family
DDJ96_RS10905	COG2011	ABC-type metal ion transport system permease component
DDJ96_RS10910	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DDJ96_RS10965	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DDJ96_RS10970	COG0105	UTP biosynthetic process
DDJ96_RS10980	COG1368	sulfuric ester hydrolase activity
DDJ96_RS10990	COG2723	6-phospho-beta-galactosidase activity
DDJ96_RS11005	COG1428	Deoxynucleoside kinase
DDJ96_RS11015	COG1611	Belongs to the LOG family
DDJ96_RS11035	COG3964	amidohydrolase
DDJ96_RS11045	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DDJ96_RS11050	COG2188	Transcriptional regulator
DDJ96_RS11055	COG2723	6-phospho-beta-galactosidase activity
DDJ96_RS11060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDJ96_RS11060	COG2190	(PTS) system
DDJ96_RS11060	COG1263	PTS System
DDJ96_RS11065	COG3711	transcriptional antiterminator
DDJ96_RS11070	COG3764	Sortase (surface protein transpeptidase)
DDJ96_RS11080	COG2814	Major facilitator Superfamily
DDJ96_RS11085	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
DDJ96_RS11090	COG0613	PHP domain protein
DDJ96_RS11095	COG3639	organic phosphonate transmembrane transporter activity
DDJ96_RS11105	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
DDJ96_RS11115	COG1597	lipid kinase activity
DDJ96_RS11120	COG4766	ethanolamine catabolic process
DDJ96_RS11125	COG3192	ethanolamine utilization protein
DDJ96_RS11130	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
DDJ96_RS11140	COG4869	propanediol catabolic process
DDJ96_RS11155	COG1454	alcohol dehydrogenase
DDJ96_RS11155	COG1012	belongs to the aldehyde dehydrogenase family
DDJ96_RS11165	COG4816	utilization protein
DDJ96_RS11170	COG4302	ethanolamine ammonia-lyase activity
DDJ96_RS11175	COG4303	Ethanolamine ammonia lyase large subunit
DDJ96_RS11205	COG2096	Adenosyltransferase
DDJ96_RS11220	COG2188	Transcriptional regulator
DDJ96_RS11225	COG3942	CHAP domain
DDJ96_RS11225	COG1705	Flagellar rod assembly protein muramidase FlgJ
DDJ96_RS11240	COG0210	DNA helicase
DDJ96_RS11255	COG1120	ATPase activity
DDJ96_RS11265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDJ96_RS11270	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DDJ96_RS11280	COG2723	6-phospho-beta-galactosidase activity
DDJ96_RS11325	COG0328	RNA-DNA hybrid ribonuclease activity
DDJ96_RS11390	COG2932	Transcriptional regulator
DDJ96_RS11405	COG3048	D-serine ammonia-lyase activity
DDJ96_RS11420	COG3397	chitin binding
DDJ96_RS11705	COG0582	viral genome integration into host DNA
DDJ96_RS11710	COG0719	Fe-S assembly protein
DDJ96_RS11720	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DDJ96_RS11725	COG0719	Fe-S assembly protein
DDJ96_RS11735	COG1464	Belongs to the NlpA lipoprotein family
DDJ96_RS11740	COG2011	ABC-type metal ion transport system permease component
DDJ96_RS11745	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DDJ96_RS11750	COG0509	glycine decarboxylation via glycine cleavage system
DDJ96_RS11755	COG1393	Belongs to the ArsC family
DDJ96_RS11760	COG0772	Belongs to the SEDS family
DDJ96_RS11765	COG0583	DNA-binding transcription factor activity
DDJ96_RS11775	COG2855	membrane
DDJ96_RS11780	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DDJ96_RS11785	COG0463	Glycosyl transferase, family 2
DDJ96_RS11790	COG3409	Peptidoglycan-binding domain 1 protein
DDJ96_RS11805	COG0741	lytic transglycosylase activity
DDJ96_RS11805	COG1388	LysM domain
DDJ96_RS11820	COG3940	Belongs to the glycosyl hydrolase 43 family
DDJ96_RS11830	COG0395	ABC-type sugar transport system, permease component
DDJ96_RS11835	COG1175	transmembrane transport
DDJ96_RS11850	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DDJ96_RS11855	COG1263	PTS System
DDJ96_RS11855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDJ96_RS11860	COG1737	Transcriptional regulator
DDJ96_RS11865	COG0363	glucosamine-6-phosphate deaminase activity
DDJ96_RS11875	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DDJ96_RS11880	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DDJ96_RS11880	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DDJ96_RS11890	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DDJ96_RS11890	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DDJ96_RS11905	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DDJ96_RS11915	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DDJ96_RS11920	COG0009	L-threonylcarbamoyladenylate synthase
DDJ96_RS11925	COG2890	protein-(glutamine-N5) methyltransferase activity
DDJ96_RS11930	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DDJ96_RS11935	COG1435	thymidine kinase activity
DDJ96_RS11950	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DDJ96_RS11955	COG0681	Belongs to the peptidase S26 family
DDJ96_RS11970	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DDJ96_RS11975	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DDJ96_RS11980	COG3442	glutamine amidotransferase
DDJ96_RS11985	COG0246	Mannitol dehydrogenase
DDJ96_RS11990	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDJ96_RS11995	COG2213	PTS system mannitol-specific
DDJ96_RS12045	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDJ96_RS12050	COG3711	transcriptional antiterminator
DDJ96_RS12055	COG2213	PTS system mannitol-specific
DDJ96_RS12060	COG4975	Glucose uptake
DDJ96_RS12065	COG1869	D-ribose catabolic process
DDJ96_RS12075	COG1482	cell wall glycoprotein biosynthetic process
DDJ96_RS12110	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DDJ96_RS12120	COG2706	6-phosphogluconolactonase activity
DDJ96_RS12130	COG0628	permease
DDJ96_RS12140	COG1368	sulfuric ester hydrolase activity
DDJ96_RS12145	COG3940	Belongs to the glycosyl hydrolase 43 family
DDJ96_RS12150	COG3534	alpha-L-arabinofuranosidase
DDJ96_RS12160	COG0395	ABC-type sugar transport system, permease component
DDJ96_RS12165	COG1175	transmembrane transport
DDJ96_RS12170	COG1653	transport
DDJ96_RS12190	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DDJ96_RS12195	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DDJ96_RS12205	COG0789	Transcriptional regulator
DDJ96_RS12210	COG1609	Transcriptional regulator
DDJ96_RS12220	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DDJ96_RS12225	COG0459	protein refolding
DDJ96_RS12230	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DDJ96_RS12240	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DDJ96_RS12255	COG5002	protein histidine kinase activity
DDJ96_RS12260	COG0745	RESPONSE REGULATOR receiver
DDJ96_RS12275	COG1307	EDD domain protein, DegV family
DDJ96_RS12290	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DDJ96_RS12295	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DDJ96_RS12300	COG3716	PTS system mannose fructose sorbose family IID component
DDJ96_RS12305	COG3715	PTS system
DDJ96_RS12320	COG3933	PFAM sigma-54 factor interaction domain-containing protein
DDJ96_RS12320	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DDJ96_RS12325	COG0383	alpha-mannosidase activity
DDJ96_RS12330	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDJ96_RS12330	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDJ96_RS12330	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDJ96_RS12335	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDJ96_RS12355	COG0561	phosphatase activity
DDJ96_RS12365	COG4175	Glycine betaine
DDJ96_RS12365	COG3448	diguanylate cyclase activity
DDJ96_RS12385	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DDJ96_RS12390	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DDJ96_RS12395	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DDJ96_RS12405	COG0686	Belongs to the AlaDH PNT family
DDJ96_RS12420	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DDJ96_RS12465	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDJ96_RS12465	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDJ96_RS12470	COG2188	Transcriptional regulator
DDJ96_RS12475	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DDJ96_RS12485	COG0628	permease
DDJ96_RS12490	COG1285	pathogenesis
DDJ96_RS12495	COG0363	glucosamine-6-phosphate deaminase activity
DDJ96_RS12500	COG2814	Major facilitator Superfamily
DDJ96_RS12530	COG0222	ribosome binding
DDJ96_RS12535	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DDJ96_RS12540	COG0081	regulation of translation
DDJ96_RS12545	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DDJ96_RS12550	COG1760	l-serine dehydratase
DDJ96_RS12555	COG1760	l-serine dehydratase
DDJ96_RS12560	COG0402	S-adenosylhomocysteine deaminase activity
DDJ96_RS12565	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DDJ96_RS12575	COG3842	ATPase activity
DDJ96_RS12585	COG1176	ABC-type spermidine putrescine transport system, permease component I
DDJ96_RS12595	COG0250	Participates in transcription elongation, termination and antitermination
DDJ96_RS12610	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DDJ96_RS12625	COG1597	lipid kinase activity
DDJ96_RS12630	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DDJ96_RS12645	COG0500	methyltransferase
DDJ96_RS12650	COG3142	Participates in the control of copper homeostasis
DDJ96_RS12655	COG2239	Acts as a magnesium transporter
DDJ96_RS12660	COG0564	pseudouridine synthase activity
DDJ96_RS12665	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DDJ96_RS12670	COG2357	RelA SpoT domain protein
DDJ96_RS12700	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DDJ96_RS12705	COG3959	Transketolase, thiamine diphosphate binding domain
DDJ96_RS12720	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDJ96_RS12730	COG1063	alcohol dehydrogenase
DDJ96_RS12745	COG4862	establishment of competence for transformation
DDJ96_RS12750	COG1393	Belongs to the ArsC family
DDJ96_RS12760	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DDJ96_RS12765	COG0419	ATPase involved in DNA repair
DDJ96_RS12775	COG0204	Acyl-transferase
DDJ96_RS12780	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DDJ96_RS12785	COG2827	Endonuclease containing a URI domain
DDJ96_RS12815	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DDJ96_RS12820	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DDJ96_RS12825	COG0124	histidyl-tRNA synthetase
DDJ96_RS12835	COG0667	Aldo Keto reductase
DDJ96_RS12850	COG2124	cytochrome p450
DDJ96_RS12860	COG1490	D-aminoacyl-tRNA deacylase activity
DDJ96_RS12865	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DDJ96_RS12870	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DDJ96_RS12875	COG2264	protein methyltransferase activity
DDJ96_RS12885	COG2094	Belongs to the DNA glycosylase MPG family
DDJ96_RS12890	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DDJ96_RS12905	COG0589	response to stress
DDJ96_RS12955	COG1876	peptidase activity
DDJ96_RS12965	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DDJ96_RS12970	COG0827	DNA restriction-modification system
DDJ96_RS12995	COG4537	Required for transformation and DNA binding
DDJ96_RS13000	COG1459	type II secretion system
DDJ96_RS13005	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DDJ96_RS13015	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DDJ96_RS13025	COG4473	ABC transporter
DDJ96_RS13030	COG1131	(ABC) transporter
DDJ96_RS13035	COG0537	adenosine 5'-monophosphoramidase activity
DDJ96_RS13045	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DDJ96_RS13050	COG3481	metal-dependent phosphohydrolase, HD sub domain
DDJ96_RS13055	COG4717	serine-type aminopeptidase activity
DDJ96_RS13080	COG3507	Belongs to the glycosyl hydrolase 43 family
DDJ96_RS13095	COG1073	alpha beta
DDJ96_RS13105	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DDJ96_RS13110	COG1653	transport
DDJ96_RS13120	COG4209	transmembrane transport
DDJ96_RS13125	COG0395	ABC-type sugar transport system, permease component
DDJ96_RS13130	COG2207	Transcriptional regulator
DDJ96_RS13135	COG0246	Mannitol dehydrogenase
DDJ96_RS13140	COG2721	sulfolactate sulfo-lyase activity
DDJ96_RS13145	COG1904	glucuronate isomerase
DDJ96_RS13150	COG2755	lipolytic protein G-D-S-L family
DDJ96_RS13160	COG3679	Belongs to the UPF0342 family
DDJ96_RS13165	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DDJ96_RS13170	COG0564	pseudouridine synthase activity
DDJ96_RS13195	COG0383	alpha-mannosidase activity
DDJ96_RS13220	COG4753	response regulator
DDJ96_RS13220	COG2207	Transcriptional regulator
DDJ96_RS13225	COG2972	Histidine kinase
DDJ96_RS13235	COG1653	transport
DDJ96_RS13240	COG0395	ABC-type sugar transport system, permease component
DDJ96_RS13245	COG1175	transmembrane transport
DDJ96_RS13250	COG1187	pseudouridine synthase activity
DDJ96_RS13255	COG2244	polysaccharide biosynthetic process
DDJ96_RS13260	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DDJ96_RS13265	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DDJ96_RS13275	COG1447	Phosphotransferase system cellobiose-specific component IIA
DDJ96_RS13280	COG3711	transcriptional antiterminator
DDJ96_RS13280	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDJ96_RS13295	COG0495	leucyl-tRNA aminoacylation
DDJ96_RS13300	COG1705	Flagellar rod assembly protein muramidase FlgJ
DDJ96_RS13300	COG1388	LysM domain
DDJ96_RS13305	COG0671	phosphoesterase, PA-phosphatase related
DDJ96_RS13310	COG1242	4 iron, 4 sulfur cluster binding
DDJ96_RS13315	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DDJ96_RS13325	COG1132	(ABC) transporter
DDJ96_RS13330	COG1132	(ABC) transporter
DDJ96_RS13335	COG1607	acyl-coa hydrolase
DDJ96_RS13345	COG0477	Major facilitator Superfamily
DDJ96_RS13350	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DDJ96_RS13500	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DDJ96_RS13505	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DDJ96_RS13510	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DDJ96_RS13515	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DDJ96_RS13520	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DDJ96_RS13525	COG0037	tRNA processing
DDJ96_RS13530	COG1098	S1 RNA binding domain
DDJ96_RS13540	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DDJ96_RS13545	COG2244	polysaccharide biosynthetic process
DDJ96_RS13550	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DDJ96_RS13555	COG0193	aminoacyl-tRNA hydrolase activity
DDJ96_RS13560	COG0039	L-malate dehydrogenase activity
DDJ96_RS13590	COG1792	Involved in formation and maintenance of cell shape
DDJ96_RS13600	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DDJ96_RS13605	COG1162	GTPase activity
DDJ96_RS13610	COG0515	serine threonine protein kinase
DDJ96_RS13610	COG2815	serine threonine protein kinase
DDJ96_RS13615	COG0631	protein serine/threonine phosphatase activity
DDJ96_RS13620	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DDJ96_RS13620	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DDJ96_RS13625	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DDJ96_RS13630	COG0242	peptide deformylase activity
DDJ96_RS13635	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DDJ96_RS13640	COG1758	RNA polymerase activity
DDJ96_RS13645	COG0194	GDP metabolic process
DDJ96_RS13650	COG1561	YicC-like family, N-terminal region
DDJ96_RS13675	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DDJ96_RS13680	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DDJ96_RS13685	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DDJ96_RS13690	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DDJ96_RS13695	COG1121	(ABC) transporter
DDJ96_RS13700	COG3443	Belongs to the bacterial solute-binding protein 9 family
DDJ96_RS13700	COG0803	Belongs to the bacterial solute-binding protein 9 family
DDJ96_RS13705	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DDJ96_RS13710	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DDJ96_RS13710	COG0392	lysyltransferase activity
DDJ96_RS13715	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DDJ96_RS13730	COG1418	mRNA catabolic process
DDJ96_RS13740	COG1546	Belongs to the CinA family
DDJ96_RS13740	COG1058	Belongs to the CinA family
DDJ96_RS13745	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DDJ96_RS13750	COG1426	Protein conserved in bacteria
DDJ96_RS13755	COG0612	Peptidase, M16
DDJ96_RS13760	COG0612	Peptidase, M16
DDJ96_RS13765	COG1970	mechanosensitive ion channel activity
DDJ96_RS13770	COG2153	protein acetylation
DDJ96_RS13775	COG4466	Protein conserved in bacteria
DDJ96_RS13785	COG3688	RNA-binding protein containing a PIN domain
DDJ96_RS13795	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DDJ96_RS13800	COG0215	cysteine-tRNA ligase activity
DDJ96_RS13805	COG1045	serine acetyltransferase
DDJ96_RS13810	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DDJ96_RS13815	COG4956	integral membrane protein (PIN domain superfamily)
DDJ96_RS13825	COG0756	dUTP diphosphatase activity
DDJ96_RS13830	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DDJ96_RS13835	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DDJ96_RS13850	COG1705	Flagellar rod assembly protein muramidase FlgJ
DDJ96_RS13850	COG1388	LysM domain
DDJ96_RS13855	COG1388	LysM domain
DDJ96_RS13855	COG1705	Flagellar rod assembly protein muramidase FlgJ
DDJ96_RS13860	COG0702	epimerase
DDJ96_RS13865	COG1959	2 iron, 2 sulfur cluster binding
DDJ96_RS13910	COG4499	WXG100 protein secretion system (Wss), protein YukC
DDJ96_RS13930	COG4842	Belongs to the WXG100 family
DDJ96_RS13940	COG1562	ergosterol biosynthetic process
DDJ96_RS13950	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DDJ96_RS13960	COG0842	Transport permease protein
DDJ96_RS13965	COG1131	(ABC) transporter
DDJ96_RS13970	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DDJ96_RS13980	COG1070	Carbohydrate kinase
DDJ96_RS13990	COG1172	Belongs to the binding-protein-dependent transport system permease family
DDJ96_RS13995	COG1129	ABC transporter
DDJ96_RS14000	COG3507	Belongs to the glycosyl hydrolase 43 family
DDJ96_RS14005	COG2115	Belongs to the xylose isomerase family
DDJ96_RS14010	COG1940	carbohydrate kinase activity
DDJ96_RS14020	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DDJ96_RS14025	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DDJ96_RS14045	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDJ96_RS14220	COG5484	DNA packaging
DDJ96_RS14220	COG3728	DNA packaging
DDJ96_RS14345	COG3646	Phage regulatory protein
DDJ96_RS14345	COG3645	SOS response
DDJ96_RS14380	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DDJ96_RS14385	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DDJ96_RS14395	COG0165	Argininosuccinate lyase
DDJ96_RS14410	COG0783	Belongs to the Dps family
DDJ96_RS14420	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DDJ96_RS14425	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DDJ96_RS14430	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DDJ96_RS14445	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
DDJ96_RS14445	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
DDJ96_RS14470	COG0142	geranyltranstransferase activity
DDJ96_RS14490	COG4939	FMN-binding domain protein
DDJ96_RS14560	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DDJ96_RS14565	COG0826	peptidase U32
DDJ96_RS14570	COG0826	peptidase U32
DDJ96_RS14575	COG0542	response to heat
DDJ96_RS14580	COG4463	regulation of RNA biosynthetic process
DDJ96_RS14660	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DDJ96_RS14665	COG0517	IMP dehydrogenase activity
DDJ96_RS14665	COG0516	GMP reductase activity
DDJ96_RS14680	COG0012	GTP binding
DDJ96_RS14685	COG4481	Protein conserved in bacteria
DDJ96_RS14690	COG1475	DNA binding
DDJ96_RS14695	COG1192	Involved in chromosome partitioning
DDJ96_RS14700	COG0357	Ribosomal RNA small subunit methyltransferase G
DDJ96_RS14720	COG0445	tRNA wobble uridine modification
DDJ96_RS14725	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DDJ96_RS14735	COG1847	R3H domain protein
DDJ96_RS14740	COG0706	membrane insertase activity
DDJ96_RS14745	COG0594	ribonuclease P activity
DDJ96_RS14750	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DDJ96_RS14955	COG3843	relaxase mobilization nuclease domain protein
DDJ96_RS15015	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DDJ96_RS15030	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DDJ96_RS15055	COG1192	Involved in chromosome partitioning
DDJ96_RS15075	COG5002	protein histidine kinase activity
DDJ96_RS15110	COG3654	unkown
DDJ96_RS15120	COG4974	Belongs to the 'phage' integrase family
DDJ96_RS15135	COG1192	Involved in chromosome partitioning
DDJ96_RS15205	COG3843	relaxase mobilization nuclease domain protein
DDJ96_RS15230	COG1733	regulation of RNA biosynthetic process
DDJ96_RS15235	COG1902	pentaerythritol trinitrate reductase activity
DDJ96_RS15295	COG1278	Cold shock
DDJ96_RS15330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DDJ96_RS15335	COG1136	(ABC) transporter
DDJ96_RS15340	COG0577	efflux transmembrane transporter activity