locus-tag	class	description
EIB74_RS00010	COG0049	tRNA binding
EIB74_RS00015	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EIB74_RS00020	COG0783	Belongs to the Dps family
EIB74_RS00035	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EIB74_RS00035	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EIB74_RS00035	COG1703	isobutyryl-CoA mutase activity
EIB74_RS00050	COG1349	DNA-binding transcription factor activity
EIB74_RS00055	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EIB74_RS00065	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EIB74_RS00085	COG2801	Transposase and inactivated derivatives
EIB74_RS00125	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EIB74_RS00130	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EIB74_RS00135	COG1607	acyl-coa hydrolase
EIB74_RS00190	COG0564	pseudouridine synthase activity
EIB74_RS00200	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EIB74_RS00210	COG2217	Heavy metal translocating P-type atpase
EIB74_RS00260	COG1611	Belongs to the LOG family
EIB74_RS00265	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EIB74_RS00280	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EIB74_RS00290	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EIB74_RS00295	COG2321	neutral zinc metallopeptidase
EIB74_RS00360	COG1216	Glycosyl transferase, family 2
EIB74_RS00360	COG1442	glycosyl transferase family 8
EIB74_RS00395	COG1278	Cold shock
EIB74_RS00420	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EIB74_RS00425	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EIB74_RS00440	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EIB74_RS00445	COG0180	Tryptophanyl-tRNA synthetase
EIB74_RS00475	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EIB74_RS00490	COG0697	spore germination
EIB74_RS00495	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EIB74_RS00535	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EIB74_RS00535	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EIB74_RS00540	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EIB74_RS00550	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EIB74_RS00555	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EIB74_RS00570	COG0438	transferase activity, transferring glycosyl groups
EIB74_RS00580	COG2181	nitrate reductase activity
EIB74_RS00580	COG0247	lactate metabolic process
EIB74_RS00585	COG0247	lactate metabolic process
EIB74_RS00585	COG2181	nitrate reductase activity
EIB74_RS00590	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EIB74_RS00640	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EIB74_RS00650	COG2076	Multidrug Resistance protein
EIB74_RS00660	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EIB74_RS00665	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EIB74_RS00670	COG0217	transcriptional regulatory protein
EIB74_RS00680	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EIB74_RS00685	COG0488	(ABC) transporter
EIB74_RS00690	COG0772	Belongs to the SEDS family
EIB74_RS00695	COG0768	penicillin binding
EIB74_RS00710	COG1077	Cell shape determining protein MreB Mrl
EIB74_RS00715	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EIB74_RS00720	COG0181	hydroxymethylbilane synthase activity
EIB74_RS00735	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EIB74_RS00775	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EIB74_RS00780	COG1764	response to oxidative stress
EIB74_RS00785	COG3591	Belongs to the peptidase S1B family
EIB74_RS00790	COG2801	Transposase and inactivated derivatives
EIB74_RS00800	COG2963	transposase activity
EIB74_RS00805	COG0387	Pfam Sodium calcium exchanger
EIB74_RS00835	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EIB74_RS00840	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EIB74_RS00895	COG4974	Belongs to the 'phage' integrase family
EIB74_RS00945	COG1505	serine-type exopeptidase activity
EIB74_RS00990	COG4771	TonB-dependent receptor
EIB74_RS01160	COG0587	DNA-directed DNA polymerase activity
EIB74_RS01165	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EIB74_RS01270	COG0739	heme binding
EIB74_RS01335	COG2166	iron-sulfur cluster assembly
EIB74_RS01340	COG2195	Cleaves the N-terminal amino acid of tripeptides
EIB74_RS01355	COG2151	metal-sulfur cluster biosynthetic enzyme
EIB74_RS01385	COG0437	4 iron, 4 sulfur cluster binding
EIB74_RS01390	COG3474	cytochrome
EIB74_RS01420	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EIB74_RS01425	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EIB74_RS01435	COG1774	PSP1 C-terminal conserved region
EIB74_RS01450	COG1959	2 iron, 2 sulfur cluster binding
EIB74_RS01460	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EIB74_RS01490	COG1401	restriction endodeoxyribonuclease activity
EIB74_RS01495	COG0481	GTPase activity
EIB74_RS01520	COG0497	DNA recombination
EIB74_RS01530	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EIB74_RS01535	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EIB74_RS01545	COG1610	YqeY-like protein
EIB74_RS01550	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EIB74_RS01570	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EIB74_RS01575	COG2827	Endonuclease containing a URI domain
EIB74_RS01580	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EIB74_RS01590	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EIB74_RS01595	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EIB74_RS01600	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EIB74_RS01605	COG0768	penicillin binding
EIB74_RS01615	COG0275	rRNA processing
EIB74_RS01620	COG2001	Belongs to the MraZ family
EIB74_RS01625	COG0778	Nitroreductase
EIB74_RS01640	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EIB74_RS01645	COG0157	Belongs to the NadC ModD family
EIB74_RS01660	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EIB74_RS01685	COG0791	NLP P60 protein
EIB74_RS01700	COG2733	membrane
EIB74_RS01715	COG0084	hydrolase, TatD family'
EIB74_RS01720	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EIB74_RS01725	COG0594	ribonuclease P activity
EIB74_RS01735	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EIB74_RS01740	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EIB74_RS01745	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EIB74_RS01755	COG0688	phosphatidylethanolamine metabolic process
EIB74_RS01760	COG4589	Belongs to the CDS family
EIB74_RS01770	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EIB74_RS01775	COG0799	negative regulation of ribosome biogenesis
EIB74_RS01780	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EIB74_RS01780	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EIB74_RS01790	COG0343	queuine tRNA-ribosyltransferase activity
EIB74_RS01800	COG0463	Glycosyl transferase, family 2
EIB74_RS01805	COG1505	serine-type exopeptidase activity
EIB74_RS01810	COG1271	oxidase subunit
EIB74_RS01825	COG1741	Belongs to the pirin family
EIB74_RS01830	COG0750	zinc metalloprotease
EIB74_RS01890	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EIB74_RS01895	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EIB74_RS01910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EIB74_RS01925	COG2608	mercury ion transmembrane transporter activity
EIB74_RS01945	COG1830	Aldolase
EIB74_RS01955	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EIB74_RS01975	COG2132	Multicopper oxidase
EIB74_RS01980	COG2217	Heavy metal translocating P-type atpase
EIB74_RS01985	COG2814	Major facilitator Superfamily
EIB74_RS02020	COG4974	Belongs to the 'phage' integrase family
EIB74_RS02045	COG2801	Transposase and inactivated derivatives
EIB74_RS02075	COG1476	TRANSCRIPTIONal
EIB74_RS02115	COG2133	pyrroloquinoline quinone binding
EIB74_RS02120	COG3385	transposase activity
EIB74_RS02130	COG1214	PFAM Peptidase M22, glycoprotease
EIB74_RS02145	COG4221	oxidoreductase activity
EIB74_RS02155	COG1960	acyl-CoA dehydrogenase activity
EIB74_RS02180	COG0167	dihydroorotate dehydrogenase activity
EIB74_RS02200	COG0423	glycine-tRNA ligase activity
EIB74_RS02220	COG0166	Belongs to the GPI family
EIB74_RS02225	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EIB74_RS02230	COG0602	queuosine metabolic process
EIB74_RS02235	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EIB74_RS02240	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EIB74_RS02270	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EIB74_RS02280	COG2081	HI0933 family
EIB74_RS02295	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EIB74_RS02305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EIB74_RS02305	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EIB74_RS02310	COG3118	belongs to the thioredoxin family
EIB74_RS02345	COG1770	oligopeptidase
EIB74_RS02375	COG0792	nuclease activity
EIB74_RS02380	COG1619	proteins homologs of microcin C7 resistance protein MccF
EIB74_RS02390	COG0557	exoribonuclease II activity
EIB74_RS02400	COG0698	ribose 5-phosphate isomerase
EIB74_RS02405	COG0126	phosphoglycerate kinase activity
EIB74_RS02415	COG0445	tRNA wobble uridine modification
EIB74_RS02420	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EIB74_RS02430	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EIB74_RS02445	COG1435	thymidine kinase activity
EIB74_RS02455	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EIB74_RS02470	COG1028	Short-chain dehydrogenase reductase Sdr
EIB74_RS02475	COG0247	lactate metabolic process
EIB74_RS02505	COG3682	Transcriptional regulator
EIB74_RS02515	COG0556	nucleotide-excision repair
EIB74_RS02535	COG0628	permease
EIB74_RS02550	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EIB74_RS02560	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EIB74_RS02575	COG3275	phosphorelay sensor kinase activity
EIB74_RS02590	COG3279	Response regulator of the LytR AlgR family
EIB74_RS02605	COG0482	sulfurtransferase activity
EIB74_RS02615	COG0542	response to heat
EIB74_RS02635	COG1703	isobutyryl-CoA mutase activity
EIB74_RS02645	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EIB74_RS02645	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EIB74_RS02650	COG0326	Molecular chaperone. Has ATPase activity
EIB74_RS02655	COG0793	Belongs to the peptidase S41A family
EIB74_RS02660	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EIB74_RS02680	COG2176	DNA-directed DNA polymerase activity
EIB74_RS02685	COG0433	COG0433 Predicted ATPase
EIB74_RS02690	COG3781	membrane
EIB74_RS02705	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EIB74_RS02710	COG0191	fructose-bisphosphate aldolase activity
EIB74_RS02715	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EIB74_RS02725	COG1464	Belongs to the NlpA lipoprotein family
EIB74_RS02730	COG0700	Nucleoside recognition
EIB74_RS02745	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EIB74_RS02750	COG2153	protein acetylation
EIB74_RS02775	COG0606	chelatase, subunit chli
EIB74_RS02780	COG0328	RNA-DNA hybrid ribonuclease activity
EIB74_RS02785	COG0305	Participates in initiation and elongation during chromosome replication
EIB74_RS02795	COG1131	(ABC) transporter
EIB74_RS02810	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EIB74_RS02850	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EIB74_RS02875	COG3033	Beta-eliminating lyase
EIB74_RS02885	COG0424	maF-like protein
EIB74_RS02890	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EIB74_RS02915	COG0758	DNA mediated transformation
EIB74_RS02940	COG1940	carbohydrate kinase activity
EIB74_RS02950	COG4773	Receptor
EIB74_RS02960	COG0653	protein targeting
EIB74_RS02970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EIB74_RS03005	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EIB74_RS03020	COG0193	aminoacyl-tRNA hydrolase activity
EIB74_RS03030	COG0659	secondary active sulfate transmembrane transporter activity
EIB74_RS03040	COG0288	reversible hydration of carbon dioxide
EIB74_RS03065	COG0438	transferase activity, transferring glycosyl groups
EIB74_RS03080	COG1215	transferase activity, transferring glycosyl groups
EIB74_RS03090	COG1216	Glycosyl transferase, family 2
EIB74_RS03095	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EIB74_RS03100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EIB74_RS03170	COG0779	Required for maturation of 30S ribosomal subunits
EIB74_RS03175	COG0195	Participates in both transcription termination and antitermination
EIB74_RS03175	COG2251	uridine kinase activity
EIB74_RS03180	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EIB74_RS03185	COG1629	transport
EIB74_RS03205	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EIB74_RS03250	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EIB74_RS03265	COG3620	sequence-specific DNA binding
EIB74_RS03270	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EIB74_RS03295	COG2234	aminopeptidase activity
EIB74_RS03300	COG1132	(ABC) transporter
EIB74_RS03305	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EIB74_RS03325	COG0719	Fe-S assembly protein
EIB74_RS03330	COG0396	ATPase activity
EIB74_RS03340	COG0719	Fe-S assembly protein
EIB74_RS03345	COG0316	Belongs to the HesB IscA family
EIB74_RS03375	COG4804	nuclease activity
EIB74_RS03380	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EIB74_RS03405	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EIB74_RS03410	COG0527	aspartate kinase activity
EIB74_RS03410	COG0460	homoserine dehydrogenase
EIB74_RS03430	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EIB74_RS03435	COG1228	amidohydrolase
EIB74_RS03440	COG0010	Belongs to the arginase family
EIB74_RS03445	COG0546	phosphoglycolate phosphatase activity
EIB74_RS03460	COG0436	Aminotransferase
EIB74_RS03465	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EIB74_RS03480	COG4974	Belongs to the 'phage' integrase family
EIB74_RS03490	COG1024	Enoyl-CoA hydratase
EIB74_RS03495	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EIB74_RS03500	COG0148	phosphopyruvate hydratase activity
EIB74_RS03575	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EIB74_RS03580	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EIB74_RS03585	COG0612	Peptidase, M16
EIB74_RS03590	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EIB74_RS03600	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EIB74_RS03635	COG0516	GMP reductase activity
EIB74_RS03635	COG0517	IMP dehydrogenase activity
EIB74_RS03645	COG0300	oxidoreductase activity
EIB74_RS03665	COG0022	dehydrogenase e1 component
EIB74_RS03670	COG1309	transcriptional regulator
EIB74_RS03675	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EIB74_RS03680	COG3396	Phenylacetate-CoA oxygenase
EIB74_RS03685	COG3460	Phenylacetate-CoA oxygenase
EIB74_RS03695	COG2151	metal-sulfur cluster biosynthetic enzyme
EIB74_RS03700	COG1250	3-hydroxyacyl-CoA dehydrogenase
EIB74_RS03710	COG0183	Belongs to the thiolase family
EIB74_RS03715	COG2030	dehydratase
EIB74_RS03715	COG1012	belongs to the aldehyde dehydrogenase family
EIB74_RS03730	COG0254	rRNA binding
EIB74_RS03785	COG2801	Transposase and inactivated derivatives
EIB74_RS03830	COG1595	DNA-templated transcription, initiation
EIB74_RS03850	COG1862	Preprotein translocase
EIB74_RS03865	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EIB74_RS03885	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EIB74_RS03915	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EIB74_RS03925	COG0658	competence protein
EIB74_RS03925	COG2333	competence protein COMEC
EIB74_RS03935	COG0248	Ppx GppA phosphatase
EIB74_RS03940	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EIB74_RS03945	COG0443	Heat shock 70 kDa protein
EIB74_RS03965	COG4974	Belongs to the 'phage' integrase family
EIB74_RS04040	COG0358	DNA primase activity
EIB74_RS04050	COG4974	Belongs to the 'phage' integrase family
EIB74_RS04055	COG4974	Belongs to the 'phage' integrase family
EIB74_RS04075	COG1505	serine-type exopeptidase activity
EIB74_RS04255	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EIB74_RS04265	COG0739	heme binding
EIB74_RS04270	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EIB74_RS04275	COG3339	Conserved Protein
EIB74_RS04280	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EIB74_RS04285	COG0489	protein tyrosine kinase activity
EIB74_RS04290	COG1301	dicarboxylic acid transport
EIB74_RS04320	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EIB74_RS04335	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EIB74_RS04340	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EIB74_RS04345	COG0052	Belongs to the universal ribosomal protein uS2 family
EIB74_RS04350	COG0825	malonyl-CoA metabolic process
EIB74_RS04355	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EIB74_RS04375	COG0438	transferase activity, transferring glycosyl groups
EIB74_RS04375	COG4641	Protein conserved in bacteria
EIB74_RS04380	COG1216	Glycosyl transferase, family 2
EIB74_RS04385	COG1216	Glycosyl transferase, family 2
EIB74_RS04385	COG1442	glycosyl transferase family 8
EIB74_RS04405	COG0439	Biotin carboxylase
EIB74_RS04415	COG0511	ligase activity, forming carbon-carbon bonds
EIB74_RS04420	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EIB74_RS04430	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EIB74_RS04440	COG5000	phosphorelay sensor kinase activity
EIB74_RS04445	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EIB74_RS04450	COG2884	Cell division ATP-binding protein ftsE
EIB74_RS04455	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EIB74_RS04470	COG1519	Transferase
EIB74_RS04470	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EIB74_RS04485	COG0495	leucyl-tRNA aminoacylation
EIB74_RS04500	COG0848	biopolymer transport protein
EIB74_RS04525	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EIB74_RS04545	COG1132	(ABC) transporter
EIB74_RS04550	COG0579	oxidoreductase
EIB74_RS04560	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EIB74_RS04565	COG0737	Belongs to the 5'-nucleotidase family
EIB74_RS04570	COG0737	Belongs to the 5'-nucleotidase family
EIB74_RS04595	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EIB74_RS04600	COG4232	protein-disulfide reductase activity
EIB74_RS04610	COG3104	oligopeptide transport
EIB74_RS04620	COG3104	oligopeptide transport
EIB74_RS04630	COG0823	Involved in the tonB-independent uptake of proteins
EIB74_RS04630	COG1506	peptidase
EIB74_RS04635	COG1054	Belongs to the UPF0176 family
EIB74_RS04640	COG0826	peptidase U32
EIB74_RS04690	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EIB74_RS04695	COG1137	ATPase activity
EIB74_RS04700	COG1132	(ABC) transporter
EIB74_RS04705	COG2096	Adenosyltransferase
EIB74_RS04745	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EIB74_RS04765	COG0450	alkyl hydroperoxide reductase
EIB74_RS04775	COG1472	Belongs to the glycosyl hydrolase 3 family
EIB74_RS04785	COG0438	transferase activity, transferring glycosyl groups
EIB74_RS04805	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EIB74_RS04810	COG1053	succinate dehydrogenase
EIB74_RS04825	COG2801	Transposase and inactivated derivatives
EIB74_RS04840	COG3590	peptidase
EIB74_RS04855	COG0017	Asparaginyl-tRNA synthetase
EIB74_RS04860	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EIB74_RS04865	COG0228	four-way junction DNA binding
EIB74_RS04875	COG0415	Belongs to the DNA photolyase family
EIB74_RS04895	COG0336	Belongs to the RNA methyltransferase TrmD family
EIB74_RS04900	COG1252	NADH dehydrogenase
EIB74_RS04910	COG4206	TonB-dependent receptor
EIB74_RS04915	COG1194	a g-specific adenine glycosylase
EIB74_RS04920	COG0776	regulation of translation
EIB74_RS04925	COG1530	ribonuclease E activity
EIB74_RS04930	COG0745	RESPONSE REGULATOR receiver
EIB74_RS04935	COG0708	Exodeoxyribonuclease III
EIB74_RS04955	COG0322	excinuclease ABC activity
EIB74_RS04980	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EIB74_RS04990	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EIB74_RS05005	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EIB74_RS05020	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EIB74_RS05035	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EIB74_RS05040	COG1028	Short-chain dehydrogenase reductase Sdr
EIB74_RS05045	COG0101	tRNA pseudouridine synthase activity
EIB74_RS05050	COG1132	(ABC) transporter
EIB74_RS05075	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EIB74_RS05085	COG0427	acetyl-CoA hydrolase
EIB74_RS05095	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
EIB74_RS05100	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EIB74_RS05110	COG0745	RESPONSE REGULATOR receiver
EIB74_RS05115	COG5002	protein histidine kinase activity
EIB74_RS05120	COG1368	sulfuric ester hydrolase activity
EIB74_RS05130	COG0671	phosphoesterase, PA-phosphatase related
EIB74_RS05140	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EIB74_RS05140	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EIB74_RS05160	COG1678	Uncharacterized ACR, COG1678
EIB74_RS05165	COG0259	pyridoxamine-phosphate oxidase activity
EIB74_RS05170	COG0860	N-Acetylmuramoyl-L-alanine amidase
EIB74_RS05170	COG2247	cell wall binding repeat
EIB74_RS05175	COG0140	phosphoribosyl-ATP diphosphatase activity
EIB74_RS05175	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EIB74_RS05180	COG0107	imidazoleglycerol-phosphate synthase activity
EIB74_RS05185	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EIB74_RS05200	COG0131	Imidazoleglycerol-phosphate dehydratase
EIB74_RS05205	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EIB74_RS05210	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EIB74_RS05215	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EIB74_RS05235	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EIB74_RS05250	COG3158	transport of potassium into the cell
EIB74_RS05285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EIB74_RS05290	COG1136	(ABC) transporter
EIB74_RS05295	COG0577	efflux transmembrane transporter activity
EIB74_RS05295	COG1136	(ABC) transporter
EIB74_RS05320	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EIB74_RS05345	COG1136	(ABC) transporter
EIB74_RS05355	COG0577	efflux transmembrane transporter activity
EIB74_RS05355	COG1136	(ABC) transporter
EIB74_RS05360	COG0577	efflux transmembrane transporter activity
EIB74_RS05360	COG1136	(ABC) transporter
EIB74_RS05365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EIB74_RS05380	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EIB74_RS05385	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EIB74_RS05395	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EIB74_RS05405	COG0004	ammonium transporteR
EIB74_RS05415	COG3425	synthase
EIB74_RS05425	COG1012	belongs to the aldehyde dehydrogenase family
EIB74_RS05440	COG1301	dicarboxylic acid transport
EIB74_RS05445	COG1546	Belongs to the CinA family
EIB74_RS05445	COG1058	Belongs to the CinA family
EIB74_RS05455	COG2814	Major facilitator Superfamily
EIB74_RS05460	COG0667	Aldo Keto reductase
EIB74_RS05485	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EIB74_RS05500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EIB74_RS05515	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EIB74_RS05525	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EIB74_RS05530	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EIB74_RS05550	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EIB74_RS05555	COG0297	glycogen (starch) synthase activity
EIB74_RS05565	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EIB74_RS05570	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EIB74_RS05595	COG0175	sulfate reduction
EIB74_RS05600	COG0175	sulfate reduction
EIB74_RS05610	COG0730	response to heat
EIB74_RS05630	COG4774	siderophore transport
EIB74_RS05635	COG0488	(ABC) transporter
EIB74_RS05680	COG0179	Fumarylacetoacetate (FAA) hydrolase
EIB74_RS05695	COG1183	phosphatidylcholine synthase activity
EIB74_RS05710	COG0022	dehydrogenase e1 component
EIB74_RS05710	COG0508	dehydrogenase complex catalyzes the overall conversion of
EIB74_RS05715	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EIB74_RS05720	COG4974	Belongs to the 'phage' integrase family
EIB74_RS05755	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EIB74_RS05785	COG3920	Histidine kinase
EIB74_RS05805	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EIB74_RS05810	COG0081	regulation of translation
EIB74_RS05815	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EIB74_RS05820	COG0222	ribosome binding
EIB74_RS05840	COG0085	RNA polymerase activity
EIB74_RS05845	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EIB74_RS05860	COG1064	alcohol dehydrogenase
EIB74_RS05880	COG0113	porphobilinogen synthase activity
EIB74_RS05890	COG1418	mRNA catabolic process
EIB74_RS05900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EIB74_RS05910	COG0525	valine-tRNA ligase activity
EIB74_RS05920	COG2326	polyphosphate kinase activity
EIB74_RS05925	COG1012	belongs to the aldehyde dehydrogenase family
EIB74_RS05935	COG0492	ferredoxin-NADP+ reductase activity
EIB74_RS05950	COG3040	lipid binding
EIB74_RS05955	COG0633	Ferredoxin
EIB74_RS05960	COG0492	ferredoxin-NADP+ reductase activity
EIB74_RS06005	COG3385	transposase activity
EIB74_RS06020	COG1250	3-hydroxyacyl-CoA dehydrogenase
EIB74_RS06040	COG0673	inositol 2-dehydrogenase activity
EIB74_RS06045	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EIB74_RS06050	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EIB74_RS06055	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EIB74_RS06060	COG3956	TIGRFAM MazG family protein
EIB74_RS06065	COG1704	LemA family
EIB74_RS06095	COG0488	(ABC) transporter
EIB74_RS06115	COG1528	Iron-storage protein
EIB74_RS06120	COG1629	transport
EIB74_RS06125	COG0702	epimerase
EIB74_RS06155	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EIB74_RS06155	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EIB74_RS06165	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EIB74_RS06170	COG0671	phosphoesterase, PA-phosphatase related
EIB74_RS06175	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EIB74_RS06180	COG1295	ribonuclease BN
EIB74_RS06185	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EIB74_RS06190	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EIB74_RS06195	COG2308	Evidence 4 Homologs of previously reported genes of
EIB74_RS06205	COG1305	Transglutaminase-like
EIB74_RS06215	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EIB74_RS06225	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EIB74_RS06235	COG0436	Aminotransferase
EIB74_RS06260	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EIB74_RS06295	COG1160	GTP binding
EIB74_RS06300	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EIB74_RS06305	COG1040	competence protein
EIB74_RS06315	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EIB74_RS06320	COG2224	Isocitrate lyase
EIB74_RS06350	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EIB74_RS06360	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EIB74_RS06380	COG2244	polysaccharide biosynthetic process
EIB74_RS06435	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EIB74_RS06440	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EIB74_RS06445	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EIB74_RS06450	COG1902	pentaerythritol trinitrate reductase activity
EIB74_RS06460	COG0504	CTP synthase activity
EIB74_RS06465	COG0706	membrane insertase activity
EIB74_RS06475	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EIB74_RS06480	COG2354	Protein conserved in bacteria
EIB74_RS06495	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EIB74_RS06505	COG1522	sequence-specific DNA binding
EIB74_RS06515	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
EIB74_RS06520	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EIB74_RS06530	COG2195	Cleaves the N-terminal amino acid of tripeptides
EIB74_RS06540	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EIB74_RS06570	COG1289	transmembrane transporter activity
EIB74_RS06595	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EIB74_RS06600	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EIB74_RS06615	COG0720	synthase
EIB74_RS06625	COG3876	Protein conserved in bacteria
EIB74_RS06645	COG1446	asparaginase
EIB74_RS06650	COG4242	Belongs to the peptidase S51 family
EIB74_RS06655	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EIB74_RS06655	COG0189	ligase activity
EIB74_RS06660	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EIB74_RS06665	COG0745	RESPONSE REGULATOR receiver
EIB74_RS06670	COG5002	protein histidine kinase activity
EIB74_RS06715	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EIB74_RS06720	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EIB74_RS06730	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EIB74_RS06735	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EIB74_RS06740	COG0165	Argininosuccinate lyase
EIB74_RS06745	COG1522	sequence-specific DNA binding
EIB74_RS06755	COG0505	Belongs to the CarA family
EIB74_RS06780	COG3842	ATPase activity
EIB74_RS06790	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EIB74_RS06790	COG2169	Transcriptional regulator
EIB74_RS06840	COG3201	nicotinamide mononucleotide transporter
EIB74_RS06845	COG0531	amino acid
EIB74_RS06855	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EIB74_RS06860	COG2323	membrane
EIB74_RS06885	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
EIB74_RS06905	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EIB74_RS06925	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EIB74_RS06930	COG1247	-acetyltransferase
EIB74_RS06935	COG0798	PFAM Bile acid sodium symporter
EIB74_RS06950	COG0640	Transcriptional regulator
EIB74_RS06955	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EIB74_RS06960	COG1301	dicarboxylic acid transport
EIB74_RS06965	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EIB74_RS06970	COG0628	permease
EIB74_RS06985	COG1193	negative regulation of DNA recombination
EIB74_RS06995	COG0517	IMP dehydrogenase activity
EIB74_RS07000	COG4974	Belongs to the 'phage' integrase family
EIB74_RS07025	COG4974	Belongs to the 'phage' integrase family
EIB74_RS07035	COG0517	IMP dehydrogenase activity
EIB74_RS07040	COG4974	Belongs to the 'phage' integrase family
EIB74_RS07085	COG0583	DNA-binding transcription factor activity
EIB74_RS07090	COG2855	membrane
EIB74_RS07130	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EIB74_RS07130	COG0321	lipoyl(octanoyl) transferase activity
EIB74_RS07165	COG0242	peptide deformylase activity
EIB74_RS07170	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EIB74_RS07180	COG1595	DNA-templated transcription, initiation
EIB74_RS07185	COG1131	(ABC) transporter
EIB74_RS07190	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EIB74_RS07205	COG0156	8-amino-7-oxononanoate synthase activity
EIB74_RS07210	COG0335	large ribosomal subunit rRNA binding
EIB74_RS07215	COG0545	Peptidyl-prolyl cis-trans isomerase
EIB74_RS07220	COG2217	Heavy metal translocating P-type atpase
EIB74_RS07240	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EIB74_RS07245	COG0308	aminopeptidase N
EIB74_RS07270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EIB74_RS07275	COG1136	(ABC) transporter
EIB74_RS07280	COG3275	phosphorelay sensor kinase activity
EIB74_RS07285	COG3279	Response regulator of the LytR AlgR family
EIB74_RS07295	COG0517	IMP dehydrogenase activity
EIB74_RS07295	COG0617	tRNA 3'-terminal CCA addition
EIB74_RS07295	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EIB74_RS07300	COG0009	L-threonylcarbamoyladenylate synthase
EIB74_RS07320	COG3340	Belongs to the peptidase S51 family
EIB74_RS07335	COG0823	Involved in the tonB-independent uptake of proteins
EIB74_RS07335	COG1506	peptidase
EIB74_RS07345	COG5002	protein histidine kinase activity
EIB74_RS07350	COG0513	Belongs to the DEAD box helicase family
EIB74_RS07355	COG5212	phosphodiesterase
EIB74_RS07360	COG1668	transmembrane transport
EIB74_RS07365	COG4152	abc transporter atp-binding protein
EIB74_RS07380	COG0346	lactoylglutathione lyase activity
EIB74_RS07390	COG0730	response to heat
EIB74_RS07405	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EIB74_RS07415	COG0697	spore germination
EIB74_RS07420	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EIB74_RS07435	COG0686	Belongs to the AlaDH PNT family
EIB74_RS07440	COG0802	atpase or kinase
EIB74_RS07445	COG0358	DNA primase activity
EIB74_RS07465	COG1028	Short-chain dehydrogenase reductase Sdr
EIB74_RS07475	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EIB74_RS07485	COG2211	Major facilitator Superfamily
EIB74_RS07495	COG1169	isochorismate synthase
EIB74_RS07500	COG2050	protein possibly involved in aromatic compounds catabolism
EIB74_RS07520	COG0460	homoserine dehydrogenase
EIB74_RS07520	COG0527	aspartate kinase activity
EIB74_RS07525	COG0083	homoserine kinase activity
EIB74_RS07530	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EIB74_RS07535	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EIB74_RS07540	COG2890	protein-(glutamine-N5) methyltransferase activity
EIB74_RS07545	COG3022	response to hydroperoxide
EIB74_RS07550	COG0009	L-threonylcarbamoyladenylate synthase
EIB74_RS07585	COG1970	mechanosensitive ion channel activity
EIB74_RS07590	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EIB74_RS07590	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EIB74_RS07600	COG2177	Part of the ABC transporter FtsEX involved in
EIB74_RS07610	COG1968	undecaprenyl-diphosphatase activity
EIB74_RS07615	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EIB74_RS07625	COG1187	pseudouridine synthase activity
EIB74_RS07640	COG0513	Belongs to the DEAD box helicase family
EIB74_RS07645	COG2189	Belongs to the N(4) N(6)-methyltransferase family
EIB74_RS07655	COG3421	Type III restriction
EIB74_RS07660	COG0539	negative regulation of cytoplasmic translation
EIB74_RS07660	COG2183	response to ionizing radiation
EIB74_RS07680	COG3781	membrane
EIB74_RS07695	COG0405	Gamma-glutamyltransferase
EIB74_RS07700	COG0071	Belongs to the small heat shock protein (HSP20) family
EIB74_RS07705	COG1418	mRNA catabolic process
EIB74_RS07725	COG2226	methyltransferase
EIB74_RS07735	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EIB74_RS07735	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EIB74_RS07745	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EIB74_RS07760	COG0626	cystathionine gamma-synthase activity
EIB74_RS07765	COG1247	-acetyltransferase
EIB74_RS07780	COG0077	Prephenate dehydratase
EIB74_RS07790	COG3609	addiction module antidote protein, CC2985 family
EIB74_RS07795	COG0531	amino acid
EIB74_RS07805	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EIB74_RS07810	COG0252	asparaginase activity
EIB74_RS07820	COG1085	galactose-1-phosphate uridylyltransferase
EIB74_RS07825	COG0561	phosphatase activity
EIB74_RS07835	COG1012	belongs to the aldehyde dehydrogenase family
EIB74_RS07860	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EIB74_RS07865	COG1607	acyl-coa hydrolase
EIB74_RS07880	COG0508	dehydrogenase complex catalyzes the overall conversion of
EIB74_RS07895	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EIB74_RS07930	COG0183	Belongs to the thiolase family
EIB74_RS07935	COG2270	Major facilitator Superfamily
EIB74_RS07980	COG5002	protein histidine kinase activity
EIB74_RS07985	COG0745	RESPONSE REGULATOR receiver
EIB74_RS07990	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EIB74_RS08000	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EIB74_RS08015	COG2824	Alkylphosphonate utilization operon protein PhnA
EIB74_RS08020	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EIB74_RS08025	COG0386	Belongs to the glutathione peroxidase family
EIB74_RS08030	COG2197	response regulator
EIB74_RS08085	COG0604	alcohol dehydrogenase
EIB74_RS08100	COG4974	Belongs to the 'phage' integrase family
EIB74_RS08120	COG4974	Belongs to the 'phage' integrase family
EIB74_RS08145	COG4974	Belongs to the 'phage' integrase family
EIB74_RS08150	COG0517	IMP dehydrogenase activity
EIB74_RS08180	COG4974	Belongs to the 'phage' integrase family
EIB74_RS08190	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EIB74_RS08195	COG0297	glycogen (starch) synthase activity
EIB74_RS08200	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EIB74_RS08210	COG0484	heat shock protein binding
EIB74_RS08235	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EIB74_RS08250	COG0006	proline dipeptidase activity
EIB74_RS08270	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EIB74_RS08285	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EIB74_RS08290	COG4974	Belongs to the 'phage' integrase family
EIB74_RS08315	COG0358	DNA primase activity
EIB74_RS08350	COG3586	endonuclease activity
EIB74_RS08395	COG1028	Short-chain dehydrogenase reductase Sdr
EIB74_RS08405	COG3046	protein related to deoxyribodipyrimidine photolyase
EIB74_RS08430	COG0702	epimerase
EIB74_RS08510	COG3685	Protein conserved in bacteria
EIB74_RS08535	COG1858	cytochrome C peroxidase
EIB74_RS08545	COG0482	sulfurtransferase activity
EIB74_RS08565	COG1999	signal sequence binding
EIB74_RS08570	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EIB74_RS08590	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EIB74_RS08600	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EIB74_RS08605	COG1943	Transposase
EIB74_RS08610	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EIB74_RS08645	COG0693	protein deglycase activity
EIB74_RS08660	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EIB74_RS08665	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EIB74_RS08680	COG2323	membrane
EIB74_RS08685	COG1335	isochorismatase
EIB74_RS08690	COG1012	belongs to the aldehyde dehydrogenase family
EIB74_RS08705	COG0586	Pfam SNARE associated Golgi protein
EIB74_RS08710	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EIB74_RS08730	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EIB74_RS08795	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EIB74_RS08800	COG0321	lipoyl(octanoyl) transferase activity
EIB74_RS08815	COG0745	RESPONSE REGULATOR receiver
EIB74_RS08845	COG1950	PFAM Membrane protein of
EIB74_RS08860	COG0159	tryptophan synthase activity
EIB74_RS08865	COG0133	tryptophan synthase activity
EIB74_RS08870	COG0135	phosphoribosylanthranilate isomerase activity
EIB74_RS08875	COG0134	indole-3-glycerol-phosphate synthase activity
EIB74_RS08880	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EIB74_RS08885	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EIB74_RS08885	COG0512	Glutamine amidotransferase of anthranilate synthase
EIB74_RS08890	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EIB74_RS08935	COG1960	acyl-CoA dehydrogenase activity
EIB74_RS08945	COG0183	Belongs to the thiolase family
EIB74_RS08955	COG1024	Enoyl-CoA hydratase
EIB74_RS08955	COG1250	3-hydroxyacyl-CoA dehydrogenase
EIB74_RS08965	COG1120	ATPase activity
EIB74_RS08975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EIB74_RS08980	COG3118	belongs to the thioredoxin family
EIB74_RS08995	COG2949	membrane
EIB74_RS09000	COG0572	uridine kinase
EIB74_RS09010	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EIB74_RS09020	COG1187	pseudouridine synthase activity
EIB74_RS09040	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EIB74_RS09045	COG0805	protein transport
EIB74_RS09065	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EIB74_RS09065	COG0517	IMP dehydrogenase activity
EIB74_RS09070	COG0514	ATP-dependent DNA helicase (RecQ)
EIB74_RS09075	COG0438	transferase activity, transferring glycosyl groups
EIB74_RS09080	COG0494	nUDIX hydrolase
EIB74_RS09085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EIB74_RS09085	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EIB74_RS09090	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EIB74_RS09100	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EIB74_RS09110	COG4251	negative regulation of phosphorylation
EIB74_RS09120	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EIB74_RS09125	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EIB74_RS09130	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EIB74_RS09140	COG2814	Major facilitator Superfamily
EIB74_RS09160	COG0612	Peptidase, M16
EIB74_RS09180	COG4717	serine-type aminopeptidase activity
EIB74_RS09185	COG1607	acyl-coa hydrolase
EIB74_RS09200	COG2957	Belongs to the agmatine deiminase family
EIB74_RS09205	COG0477	Major facilitator Superfamily
EIB74_RS09215	COG1217	gtp-binding protein TYPA
EIB74_RS09220	COG0788	formyltetrahydrofolate deformylase activity
EIB74_RS09225	COG1649	PFAM Uncharacterised BCR, COG1649
EIB74_RS09230	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EIB74_RS09235	COG4977	sequence-specific DNA binding
EIB74_RS09245	COG0028	Belongs to the TPP enzyme family
EIB74_RS09260	COG0116	Belongs to the methyltransferase superfamily
EIB74_RS09300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EIB74_RS09305	COG0450	alkyl hydroperoxide reductase
EIB74_RS09310	COG0436	Aminotransferase
EIB74_RS09320	COG0357	Ribosomal RNA small subunit methyltransferase G
EIB74_RS09340	COG1960	acyl-CoA dehydrogenase activity
EIB74_RS09435	COG2967	ApaG domain
EIB74_RS09440	COG2176	DNA-directed DNA polymerase activity
EIB74_RS09465	COG0359	binds to the 23S rRNA
EIB74_RS09470	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EIB74_RS09475	COG0360	Binds together with S18 to 16S ribosomal RNA
EIB74_RS09480	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EIB74_RS09490	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EIB74_RS09520	COG0149	triose-phosphate isomerase activity
EIB74_RS09525	COG0346	lactoylglutathione lyase activity
EIB74_RS09550	COG2801	Transposase and inactivated derivatives
EIB74_RS09565	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EIB74_RS09580	COG1215	transferase activity, transferring glycosyl groups
EIB74_RS09605	COG1136	(ABC) transporter
EIB74_RS09610	COG2003	Belongs to the UPF0758 family
EIB74_RS09625	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EIB74_RS09630	COG2239	Acts as a magnesium transporter
EIB74_RS09650	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EIB74_RS09650	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EIB74_RS09710	COG0784	Response regulator, receiver
EIB74_RS09710	COG2205	protein histidine kinase activity
EIB74_RS09720	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EIB74_RS09725	COG0745	RESPONSE REGULATOR receiver
EIB74_RS09730	COG2205	protein histidine kinase activity
EIB74_RS09730	COG0784	Response regulator, receiver
EIB74_RS09735	COG5002	protein histidine kinase activity
EIB74_RS09770	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EIB74_RS09775	COG0196	riboflavin kinase activity
EIB74_RS09800	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EIB74_RS09815	COG0436	Aminotransferase
EIB74_RS09820	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EIB74_RS09835	COG0463	Glycosyl transferase, family 2
EIB74_RS09860	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EIB74_RS09865	COG1575	Belongs to the MenA family. Type 1 subfamily
EIB74_RS09905	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EIB74_RS09925	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EIB74_RS09935	COG1595	DNA-templated transcription, initiation
EIB74_RS09945	COG0022	dehydrogenase e1 component
EIB74_RS09950	COG1234	tRNA 3'-trailer cleavage
EIB74_RS09955	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EIB74_RS09960	COG1266	CAAX protease self-immunity
EIB74_RS09995	COG2801	Transposase and inactivated derivatives
EIB74_RS09995	COG3415	Transposase
EIB74_RS10035	COG0702	epimerase
EIB74_RS10040	COG1629	transport
EIB74_RS10040	COG4206	TonB-dependent receptor
EIB74_RS10045	COG1621	beta-fructofuranosidase activity
EIB74_RS10050	COG2814	Major facilitator Superfamily
EIB74_RS10055	COG3292	Two component regulator propeller
EIB74_RS10055	COG0745	RESPONSE REGULATOR receiver
EIB74_RS10055	COG2205	protein histidine kinase activity
EIB74_RS10065	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EIB74_RS10070	COG0587	DNA-directed DNA polymerase activity
EIB74_RS10095	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EIB74_RS10110	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EIB74_RS10130	COG1185	polyribonucleotide nucleotidyltransferase activity
EIB74_RS10150	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EIB74_RS10155	COG1914	H( )-stimulated, divalent metal cation uptake system
EIB74_RS10165	COG0442	prolyl-tRNA aminoacylation
EIB74_RS10180	COG1162	GTPase activity
EIB74_RS10185	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EIB74_RS10185	COG1605	Chorismate mutase
EIB74_RS10195	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EIB74_RS10210	COG0508	dehydrogenase complex catalyzes the overall conversion of
EIB74_RS10230	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EIB74_RS10250	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EIB74_RS10260	COG0528	UMP kinase activity
EIB74_RS10265	COG0233	cytoplasmic translational termination
EIB74_RS10280	COG0629	single-stranded DNA binding
EIB74_RS10295	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EIB74_RS10315	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EIB74_RS10335	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EIB74_RS10340	COG0484	heat shock protein binding
EIB74_RS10350	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EIB74_RS10350	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EIB74_RS10355	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EIB74_RS10375	COG0596	Alpha beta hydrolase
EIB74_RS10380	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EIB74_RS10385	COG0668	transmembrane transport
EIB74_RS10400	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EIB74_RS10405	COG2706	6-phosphogluconolactonase activity
EIB74_RS10415	COG2706	6-phosphogluconolactonase activity
EIB74_RS10420	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EIB74_RS10425	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EIB74_RS10435	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EIB74_RS10530	COG3189	MarR family transcriptional regulator
EIB74_RS10545	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EIB74_RS10555	COG1999	signal sequence binding
EIB74_RS10570	COG1959	2 iron, 2 sulfur cluster binding
EIB74_RS10580	COG0521	Mo-molybdopterin cofactor biosynthetic process
EIB74_RS10580	COG0315	cyclic pyranopterin monophosphate synthase activity
EIB74_RS10585	COG0314	molybdopterin synthase activity
EIB74_RS10600	COG0746	molybdenum cofactor guanylyltransferase activity
EIB74_RS10610	COG0303	'Molybdopterin
EIB74_RS10635	COG0437	4 iron, 4 sulfur cluster binding
EIB74_RS10640	COG0243	molybdopterin cofactor binding
EIB74_RS10685	COG0732	type I restriction modification DNA specificity domain
EIB74_RS10700	COG0531	amino acid
EIB74_RS10710	COG5002	protein histidine kinase activity
EIB74_RS10715	COG0745	RESPONSE REGULATOR receiver
EIB74_RS10725	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EIB74_RS10735	COG2027	D-alanyl-D-alanine carboxypeptidase
EIB74_RS10740	COG1272	protein, Hemolysin III
EIB74_RS10745	COG0679	Auxin Efflux Carrier
EIB74_RS10750	COG1272	protein, Hemolysin III
EIB74_RS10765	COG1363	Peptidase, m42
EIB74_RS10770	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EIB74_RS10775	COG0105	UTP biosynthetic process
EIB74_RS10780	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EIB74_RS10785	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EIB74_RS10815	COG2161	toxin-antitoxin pair type II binding
EIB74_RS10820	COG4115	mRNA cleavage
EIB74_RS10840	COG2801	Transposase and inactivated derivatives
EIB74_RS10850	COG1090	epimerase
EIB74_RS10855	COG2996	Protein conserved in bacteria
EIB74_RS10860	COG0124	histidyl-tRNA synthetase
EIB74_RS10870	COG2814	Major facilitator Superfamily
EIB74_RS10875	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EIB74_RS10880	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EIB74_RS10890	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EIB74_RS10910	COG1960	acyl-CoA dehydrogenase activity
EIB74_RS10915	COG1022	Amp-dependent synthetase and ligase
EIB74_RS10920	COG1022	Amp-dependent synthetase and ligase
EIB74_RS10935	COG2095	MarC family integral membrane protein
EIB74_RS10965	COG1333	cytochrome c biogenesis protein
EIB74_RS10965	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EIB74_RS10970	COG1674	ftsk spoiiie
EIB74_RS11005	COG0724	RNA recognition motif
EIB74_RS11010	COG4989	oxidoreductase activity
EIB74_RS11040	COG2217	Heavy metal translocating P-type atpase
EIB74_RS11055	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EIB74_RS11070	COG2873	o-acetylhomoserine
EIB74_RS11080	COG1132	(ABC) transporter
EIB74_RS11100	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EIB74_RS11110	COG1959	2 iron, 2 sulfur cluster binding
EIB74_RS11135	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EIB74_RS11140	COG1028	Short-chain dehydrogenase reductase Sdr
EIB74_RS11145	COG3871	stress protein (general stress protein 26)
EIB74_RS11150	COG1793	dna ligase
EIB74_RS11150	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EIB74_RS11155	COG1793	dna ligase
EIB74_RS11170	COG4095	Psort location CytoplasmicMembrane, score
EIB74_RS11185	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EIB74_RS11210	COG2801	Transposase and inactivated derivatives
EIB74_RS11260	COG0745	RESPONSE REGULATOR receiver
EIB74_RS11280	COG0492	ferredoxin-NADP+ reductase activity
EIB74_RS11295	COG2304	oxidoreductase activity
EIB74_RS11300	COG2304	oxidoreductase activity
EIB74_RS11325	COG0714	Associated with various cellular activities
EIB74_RS11350	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EIB74_RS11400	COG0012	GTP binding
EIB74_RS11415	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EIB74_RS11435	COG2249	NAD(P)H dehydrogenase (quinone) activity
EIB74_RS11440	COG1733	regulation of RNA biosynthetic process
EIB74_RS11465	COG5002	protein histidine kinase activity
EIB74_RS11470	COG2205	protein histidine kinase activity
EIB74_RS11480	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EIB74_RS11490	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EIB74_RS11500	COG2204	response regulator
EIB74_RS11570	COG2972	Histidine kinase
EIB74_RS11575	COG3279	Response regulator of the LytR AlgR family
EIB74_RS11600	COG3023	N-Acetylmuramoyl-L-alanine amidase
EIB74_RS11605	COG2264	protein methyltransferase activity
EIB74_RS11615	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EIB74_RS11645	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
EIB74_RS11655	COG0205	6-phosphofructokinase activity
EIB74_RS11660	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EIB74_RS11720	COG0318	PFAM AMP-dependent synthetase and ligase
EIB74_RS11735	COG0295	cytidine deaminase activity
EIB74_RS11740	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EIB74_RS11790	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EIB74_RS11795	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EIB74_RS11800	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EIB74_RS11815	COG2171	N-acyltransferase activity
EIB74_RS11820	COG0791	NLP P60 protein
EIB74_RS11825	COG1368	sulfuric ester hydrolase activity
EIB74_RS11845	COG1012	belongs to the aldehyde dehydrogenase family
EIB74_RS11855	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EIB74_RS11865	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EIB74_RS11875	COG2267	carboxylic ester hydrolase activity
EIB74_RS11895	COG0037	tRNA processing
EIB74_RS11910	COG0791	NLP P60 protein
EIB74_RS11925	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EIB74_RS11945	COG0156	8-amino-7-oxononanoate synthase activity
EIB74_RS11955	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EIB74_RS11965	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EIB74_RS11965	COG0284	orotidine-5'-phosphate decarboxylase activity
EIB74_RS11975	COG2226	methyltransferase
EIB74_RS12005	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EIB74_RS12015	COG1408	metallophosphoesterase
EIB74_RS12020	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EIB74_RS12025	COG1739	Uncharacterized protein family UPF0029
EIB74_RS12045	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EIB74_RS12050	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EIB74_RS12055	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EIB74_RS12060	COG0649	NAD binding
EIB74_RS12065	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EIB74_RS12080	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EIB74_RS12090	COG1034	ATP synthesis coupled electron transport
EIB74_RS12095	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EIB74_RS12100	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EIB74_RS12105	COG0839	Belongs to the complex I subunit 6 family
EIB74_RS12110	COG0713	ATP synthesis coupled electron transport
EIB74_RS12115	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EIB74_RS12120	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EIB74_RS12125	COG1007	ATP synthesis coupled electron transport
EIB74_RS12140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EIB74_RS12160	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EIB74_RS12200	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EIB74_RS12205	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EIB74_RS12215	COG0564	pseudouridine synthase activity
EIB74_RS12225	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EIB74_RS12230	COG0563	adenylate kinase activity
EIB74_RS12235	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EIB74_RS12240	COG0513	Belongs to the DEAD box helicase family
EIB74_RS12250	COG2801	Transposase and inactivated derivatives
EIB74_RS12260	COG0084	hydrolase, TatD family'
EIB74_RS12275	COG0306	phosphate transporter
EIB74_RS12295	COG1760	l-serine dehydratase
EIB74_RS12315	COG1764	response to oxidative stress
EIB74_RS12320	COG1846	Transcriptional regulator
EIB74_RS12325	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EIB74_RS12330	COG0598	Magnesium transport protein CorA
EIB74_RS12345	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EIB74_RS12365	COG0300	oxidoreductase activity
EIB74_RS12380	COG1629	transport
EIB74_RS12385	COG0584	glycerophosphoryl diester phosphodiesterase
EIB74_RS12395	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EIB74_RS12405	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EIB74_RS12410	COG1522	sequence-specific DNA binding
EIB74_RS12415	COG2814	Major facilitator Superfamily
EIB74_RS12430	COG1309	transcriptional regulator
EIB74_RS12435	COG0470	DNA polymerase III
EIB74_RS12465	COG1051	belongs to the nudix hydrolase family
EIB74_RS12475	COG0592	DNA-directed DNA polymerase activity
EIB74_RS12485	COG1181	Belongs to the D-alanine--D-alanine ligase family
EIB74_RS12490	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EIB74_RS12535	COG0527	aspartate kinase activity
EIB74_RS12540	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EIB74_RS12545	COG4948	Mandelate Racemase Muconate Lactonizing
EIB74_RS12550	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EIB74_RS12575	COG0517	IMP dehydrogenase activity
EIB74_RS12580	COG4974	Belongs to the 'phage' integrase family
EIB74_RS12585	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EIB74_RS12600	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EIB74_RS12605	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EIB74_RS12615	COG1702	phosphate starvation-inducible protein PhoH
EIB74_RS12630	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EIB74_RS12635	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EIB74_RS12640	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EIB74_RS12645	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EIB74_RS12655	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EIB74_RS12660	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EIB74_RS12665	COG4106	trans-aconitate 2-methyltransferase activity
EIB74_RS12670	COG0066	3-isopropylmalate dehydratase activity
EIB74_RS12705	COG1960	acyl-CoA dehydrogenase activity
EIB74_RS12725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EIB74_RS12735	COG0842	Transport permease protein
EIB74_RS12750	COG2732	(Barnase) inhibitor
EIB74_RS12765	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EIB74_RS12780	COG1981	membrane
EIB74_RS12795	COG2234	aminopeptidase activity
EIB74_RS12805	COG1253	flavin adenine dinucleotide binding
EIB74_RS12815	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EIB74_RS12820	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EIB74_RS12825	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EIB74_RS12830	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EIB74_RS12835	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EIB74_RS12840	COG0356	it plays a direct role in the translocation of protons across the membrane
EIB74_RS12855	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EIB74_RS12865	COG1629	transport
EIB74_RS12885	COG4771	TonB-dependent receptor
EIB74_RS12890	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EIB74_RS12900	COG1528	Iron-storage protein
EIB74_RS12915	COG1640	4-alpha-glucanotransferase
EIB74_RS12925	COG0215	cysteine-tRNA ligase activity
EIB74_RS12930	COG0302	gtp cyclohydrolase
EIB74_RS12935	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EIB74_RS12940	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EIB74_RS12945	COG0571	ribonuclease III activity
EIB74_RS12960	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EIB74_RS12970	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EIB74_RS12975	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EIB74_RS12980	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EIB74_RS12985	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EIB74_RS12990	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EIB74_RS12990	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EIB74_RS12995	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EIB74_RS13000	COG1078	dGTPase activity
EIB74_RS13020	COG0187	DNA topoisomerase II activity
EIB74_RS13030	COG0070	glutamate synthase
EIB74_RS13030	COG0069	glutamate synthase activity
EIB74_RS13030	COG0067	glutamate synthase
EIB74_RS13035	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EIB74_RS13040	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
EIB74_RS13045	COG4654	Cytochrome c, class I
EIB74_RS13065	COG0519	Catalyzes the synthesis of GMP from XMP
EIB74_RS13065	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EIB74_RS13070	COG0151	Belongs to the GarS family
EIB74_RS13075	COG1741	Belongs to the pirin family
EIB74_RS13080	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EIB74_RS13085	COG1119	ATPase activity
EIB74_RS13090	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EIB74_RS13095	COG0440	acetolactate synthase activity
EIB74_RS13100	COG0028	Belongs to the TPP enzyme family
EIB74_RS13105	COG0129	dihydroxy-acid dehydratase activity
EIB74_RS13125	COG0366	Alpha amylase catalytic
EIB74_RS13135	COG1082	Xylose isomerase domain protein TIM barrel
EIB74_RS13145	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EIB74_RS13150	COG1629	transport
EIB74_RS13150	COG4206	TonB-dependent receptor
EIB74_RS13155	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EIB74_RS13155	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EIB74_RS13185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EIB74_RS13195	COG2226	methyltransferase
EIB74_RS13215	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EIB74_RS13235	COG2234	aminopeptidase activity
EIB74_RS13245	COG0534	Mate efflux family protein
EIB74_RS13250	COG0018	arginyl-trna synthetase
EIB74_RS13260	COG0587	DNA-directed DNA polymerase activity
EIB74_RS13275	COG3590	peptidase
EIB74_RS13285	COG1846	Transcriptional regulator
EIB74_RS13310	COG4716	Myosin-crossreactive antigen
EIB74_RS13320	COG1250	3-hydroxyacyl-CoA dehydrogenase
EIB74_RS13405	COG2801	Transposase and inactivated derivatives
EIB74_RS13410	COG3328	transposase activity
EIB74_RS13470	COG2356	endonuclease I
EIB74_RS13475	COG0671	phosphoesterase, PA-phosphatase related
EIB74_RS13480	COG2217	Heavy metal translocating P-type atpase
EIB74_RS13485	COG1285	pathogenesis
EIB74_RS13490	COG1368	sulfuric ester hydrolase activity
EIB74_RS13500	COG3781	membrane
EIB74_RS13530	COG0798	PFAM Bile acid sodium symporter
EIB74_RS13555	COG4974	Belongs to the 'phage' integrase family
EIB74_RS13565	COG3118	belongs to the thioredoxin family
EIB74_RS13570	COG1104	cysteine desulfurase activity
EIB74_RS13580	COG0300	oxidoreductase activity
EIB74_RS13585	COG0277	FAD linked oxidase domain protein
EIB74_RS13590	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EIB74_RS13620	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EIB74_RS13630	COG1475	DNA binding
EIB74_RS13635	COG1192	Involved in chromosome partitioning
EIB74_RS13660	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EIB74_RS13680	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EIB74_RS13745	COG0789	Transcriptional regulator
EIB74_RS13865	COG1309	transcriptional regulator
EIB74_RS13885	COG1131	(ABC) transporter
EIB74_RS13890	COG1131	(ABC) transporter
EIB74_RS13895	COG0842	Transport permease protein
EIB74_RS13900	COG0842	Transport permease protein
EIB74_RS13900	COG1129	ABC transporter
EIB74_RS13910	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EIB74_RS13935	COG0798	PFAM Bile acid sodium symporter
EIB74_RS13960	COG0735	belongs to the Fur family
EIB74_RS13980	COG2217	Heavy metal translocating P-type atpase
EIB74_RS13995	COG2217	Heavy metal translocating P-type atpase
EIB74_RS14020	COG2217	Heavy metal translocating P-type atpase
EIB74_RS14045	COG2132	Multicopper oxidase
EIB74_RS14055	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EIB74_RS14080	COG0798	PFAM Bile acid sodium symporter
EIB74_RS14130	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EIB74_RS14145	COG1428	Deoxynucleoside kinase
EIB74_RS14155	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EIB74_RS14160	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EIB74_RS14170	COG0552	protein localization to endoplasmic reticulum
EIB74_RS14175	COG2261	transglycosylase associated protein
EIB74_RS14185	COG0237	dephospho-CoA kinase activity
EIB74_RS14190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EIB74_RS14195	COG2255	four-way junction helicase activity
EIB74_RS14210	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EIB74_RS14215	COG0367	asparagine synthase
EIB74_RS14225	COG0251	oxidation-reduction process
EIB74_RS14245	COG0268	Binds directly to 16S ribosomal RNA
EIB74_RS14255	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EIB74_RS14270	COG1024	Enoyl-CoA hydratase
EIB74_RS14275	COG0542	response to heat
EIB74_RS14290	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EIB74_RS14295	COG0514	ATP-dependent DNA helicase (RecQ)
EIB74_RS14320	COG0616	signal peptide processing
EIB74_RS14335	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EIB74_RS14380	COG0509	glycine decarboxylation via glycine cleavage system
EIB74_RS14390	COG0632	four-way junction helicase activity
EIB74_RS14395	COG0280	phosphate acetyltransferase
EIB74_RS14395	COG0281	malic enzyme
EIB74_RS14445	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EIB74_RS14455	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EIB74_RS14465	COG1490	D-aminoacyl-tRNA deacylase activity
EIB74_RS14480	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EIB74_RS14485	COG0194	GDP metabolic process
EIB74_RS14490	COG1561	YicC-like family, N-terminal region
EIB74_RS14495	COG1663	tetraacyldisaccharide 4'-kinase activity
EIB74_RS14520	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EIB74_RS14525	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EIB74_RS14530	COG0366	Alpha amylase catalytic
EIB74_RS14535	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EIB74_RS14540	COG1522	sequence-specific DNA binding
EIB74_RS14545	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EIB74_RS14550	COG0339	signal peptide processing
EIB74_RS14555	COG3012	SEC-C Motif Domain Protein
EIB74_RS14560	COG4628	conserved protein (DUF2132)
EIB74_RS14575	COG2986	histidine ammonia-lyase
EIB74_RS14585	COG0456	acetyltransferase
EIB74_RS14590	COG3384	dioxygenase
EIB74_RS14600	COG2353	YceI-like domain
EIB74_RS14620	COG0632	four-way junction helicase activity
EIB74_RS14645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EIB74_RS14650	COG1132	(ABC) transporter
EIB74_RS14660	COG0045	succinate-CoA ligase (ADP-forming) activity
EIB74_RS14665	COG0668	transmembrane transport
EIB74_RS14725	COG1215	transferase activity, transferring glycosyl groups
EIB74_RS14730	COG0438	transferase activity, transferring glycosyl groups
EIB74_RS14760	COG2244	polysaccharide biosynthetic process
EIB74_RS14780	COG2137	regulation of response to DNA damage stimulus
EIB74_RS14785	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EIB74_RS14800	COG2852	Protein conserved in bacteria
EIB74_RS14825	COG0813	purine-nucleoside phosphorylase activity
EIB74_RS14860	COG4974	Belongs to the 'phage' integrase family
EIB74_RS14865	COG0358	DNA primase activity
EIB74_RS14890	COG4974	Belongs to the 'phage' integrase family
EIB74_RS14895	COG0358	DNA primase activity
EIB74_RS14930	COG0203	ribosomal protein L17
EIB74_RS14935	COG0202	RNA polymerase activity
EIB74_RS14940	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EIB74_RS14945	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EIB74_RS14950	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EIB74_RS14955	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EIB74_RS14960	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EIB74_RS14970	COG0200	Binds to the 23S rRNA
EIB74_RS14975	COG1841	ribosomal large subunit assembly
EIB74_RS14980	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EIB74_RS14990	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EIB74_RS14995	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EIB74_RS15000	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EIB74_RS15005	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EIB74_RS15015	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EIB74_RS15020	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EIB74_RS15025	COG0255	Belongs to the universal ribosomal protein uL29 family
EIB74_RS15030	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EIB74_RS15035	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EIB74_RS15040	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EIB74_RS15045	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EIB74_RS15050	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EIB74_RS15060	COG0088	Forms part of the polypeptide exit tunnel
EIB74_RS15065	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EIB74_RS15085	COG0051	transcription antitermination factor activity, RNA binding
EIB74_RS15100	COG0051	transcription antitermination factor activity, RNA binding