locus-tag	class	description
EIB75_RS00010	COG1247	-acetyltransferase
EIB75_RS00015	COG0798	PFAM Bile acid sodium symporter
EIB75_RS00035	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EIB75_RS00050	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EIB75_RS00055	COG0628	permease
EIB75_RS00070	COG1193	negative regulation of DNA recombination
EIB75_RS00095	COG4974	Belongs to the 'phage' integrase family
EIB75_RS00105	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EIB75_RS00105	COG5549	protein import
EIB75_RS00115	COG0517	IMP dehydrogenase activity
EIB75_RS00120	COG4974	Belongs to the 'phage' integrase family
EIB75_RS00135	COG0517	IMP dehydrogenase activity
EIB75_RS00140	COG4974	Belongs to the 'phage' integrase family
EIB75_RS00160	COG0517	IMP dehydrogenase activity
EIB75_RS00165	COG4974	Belongs to the 'phage' integrase family
EIB75_RS00180	COG4974	Belongs to the 'phage' integrase family
EIB75_RS00235	COG0321	lipoyl(octanoyl) transferase activity
EIB75_RS00235	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EIB75_RS00265	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EIB75_RS00275	COG0242	peptide deformylase activity
EIB75_RS00280	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EIB75_RS00290	COG1595	DNA-templated transcription, initiation
EIB75_RS00295	COG1131	(ABC) transporter
EIB75_RS00305	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EIB75_RS00315	COG0308	aminopeptidase N
EIB75_RS00320	COG0156	8-amino-7-oxononanoate synthase activity
EIB75_RS00325	COG0335	large ribosomal subunit rRNA binding
EIB75_RS00330	COG0545	Peptidyl-prolyl cis-trans isomerase
EIB75_RS00335	COG2217	Heavy metal translocating P-type atpase
EIB75_RS00360	COG0308	aminopeptidase N
EIB75_RS00385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EIB75_RS00390	COG1136	(ABC) transporter
EIB75_RS00395	COG0577	efflux transmembrane transporter activity
EIB75_RS00395	COG1136	(ABC) transporter
EIB75_RS00400	COG3275	phosphorelay sensor kinase activity
EIB75_RS00415	COG3279	Response regulator of the LytR AlgR family
EIB75_RS00425	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EIB75_RS00425	COG0517	IMP dehydrogenase activity
EIB75_RS00425	COG0617	tRNA 3'-terminal CCA addition
EIB75_RS00430	COG0009	L-threonylcarbamoyladenylate synthase
EIB75_RS00450	COG3340	Belongs to the peptidase S51 family
EIB75_RS00465	COG0823	Involved in the tonB-independent uptake of proteins
EIB75_RS00465	COG1506	peptidase
EIB75_RS00475	COG4191	Histidine kinase
EIB75_RS00480	COG0513	Belongs to the DEAD box helicase family
EIB75_RS00490	COG1668	transmembrane transport
EIB75_RS00495	COG4152	abc transporter atp-binding protein
EIB75_RS00510	COG0346	lactoylglutathione lyase activity
EIB75_RS00520	COG0730	response to heat
EIB75_RS00535	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EIB75_RS00545	COG0697	spore germination
EIB75_RS00550	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EIB75_RS00565	COG0686	Belongs to the AlaDH PNT family
EIB75_RS00570	COG0802	atpase or kinase
EIB75_RS00575	COG0358	DNA primase activity
EIB75_RS00595	COG1028	Short-chain dehydrogenase reductase Sdr
EIB75_RS00605	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EIB75_RS00615	COG2211	Major facilitator Superfamily
EIB75_RS00625	COG1169	isochorismate synthase
EIB75_RS00630	COG2050	protein possibly involved in aromatic compounds catabolism
EIB75_RS00650	COG0527	aspartate kinase activity
EIB75_RS00650	COG0460	homoserine dehydrogenase
EIB75_RS00655	COG0083	homoserine kinase activity
EIB75_RS00660	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EIB75_RS00665	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EIB75_RS00670	COG2890	protein-(glutamine-N5) methyltransferase activity
EIB75_RS00675	COG3022	response to hydroperoxide
EIB75_RS00680	COG0009	L-threonylcarbamoyladenylate synthase
EIB75_RS00725	COG1970	mechanosensitive ion channel activity
EIB75_RS00990	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EIB75_RS01000	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EIB75_RS01015	COG2081	HI0933 family
EIB75_RS01025	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EIB75_RS01055	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EIB75_RS01060	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EIB75_RS01065	COG0602	queuosine metabolic process
EIB75_RS01070	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EIB75_RS01075	COG0166	Belongs to the GPI family
EIB75_RS01090	COG0423	glycine-tRNA ligase activity
EIB75_RS01100	COG0167	dihydroorotate dehydrogenase activity
EIB75_RS01125	COG1960	acyl-CoA dehydrogenase activity
EIB75_RS01135	COG4221	oxidoreductase activity
EIB75_RS01150	COG1214	PFAM Peptidase M22, glycoprotease
EIB75_RS01160	COG3385	transposase activity
EIB75_RS01165	COG2133	pyrroloquinoline quinone binding
EIB75_RS01210	COG1476	TRANSCRIPTIONal
EIB75_RS01255	COG4974	Belongs to the 'phage' integrase family
EIB75_RS01265	COG0750	zinc metalloprotease
EIB75_RS01270	COG1741	Belongs to the pirin family
EIB75_RS01295	COG1271	oxidase subunit
EIB75_RS01300	COG1505	serine-type exopeptidase activity
EIB75_RS01305	COG0463	Glycosyl transferase, family 2
EIB75_RS01315	COG0343	queuine tRNA-ribosyltransferase activity
EIB75_RS01325	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EIB75_RS01325	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EIB75_RS01330	COG0799	negative regulation of ribosome biogenesis
EIB75_RS01335	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EIB75_RS01345	COG4589	Belongs to the CDS family
EIB75_RS01350	COG0688	phosphatidylethanolamine metabolic process
EIB75_RS01360	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EIB75_RS01365	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EIB75_RS01370	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EIB75_RS01380	COG0594	ribonuclease P activity
EIB75_RS01385	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EIB75_RS01390	COG0084	hydrolase, TatD family'
EIB75_RS01405	COG2733	membrane
EIB75_RS01420	COG0791	NLP P60 protein
EIB75_RS01445	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EIB75_RS01460	COG0157	Belongs to the NadC ModD family
EIB75_RS01465	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EIB75_RS01480	COG0778	Nitroreductase
EIB75_RS01485	COG2001	Belongs to the MraZ family
EIB75_RS01490	COG0275	rRNA processing
EIB75_RS01500	COG0768	penicillin binding
EIB75_RS01505	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EIB75_RS01510	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EIB75_RS01515	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EIB75_RS01525	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EIB75_RS01535	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EIB75_RS01555	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EIB75_RS01560	COG1610	YqeY-like protein
EIB75_RS01570	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EIB75_RS01575	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EIB75_RS01585	COG0497	DNA recombination
EIB75_RS01610	COG0481	GTPase activity
EIB75_RS01615	COG2259	Doxx family
EIB75_RS01625	COG3220	belongs to the UPF0276 family
EIB75_RS01660	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EIB75_RS01670	COG1959	2 iron, 2 sulfur cluster binding
EIB75_RS01685	COG1774	PSP1 C-terminal conserved region
EIB75_RS01695	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EIB75_RS01700	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EIB75_RS01720	COG3474	cytochrome
EIB75_RS01725	COG0437	4 iron, 4 sulfur cluster binding
EIB75_RS01755	COG2151	metal-sulfur cluster biosynthetic enzyme
EIB75_RS01775	COG2195	Cleaves the N-terminal amino acid of tripeptides
EIB75_RS01780	COG2166	iron-sulfur cluster assembly
EIB75_RS01855	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EIB75_RS01860	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EIB75_RS01890	COG0387	Pfam Sodium calcium exchanger
EIB75_RS01895	COG3591	Belongs to the peptidase S1B family
EIB75_RS01900	COG1764	response to oxidative stress
EIB75_RS01905	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EIB75_RS01920	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EIB75_RS01950	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EIB75_RS01960	COG0181	hydroxymethylbilane synthase activity
EIB75_RS01965	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EIB75_RS01970	COG1077	Cell shape determining protein MreB Mrl
EIB75_RS01985	COG0768	penicillin binding
EIB75_RS01990	COG0772	Belongs to the SEDS family
EIB75_RS01995	COG0488	(ABC) transporter
EIB75_RS02000	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EIB75_RS02010	COG0217	transcriptional regulatory protein
EIB75_RS02015	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EIB75_RS02020	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EIB75_RS02030	COG2076	Multidrug Resistance protein
EIB75_RS02040	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EIB75_RS02090	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EIB75_RS02095	COG2181	nitrate reductase activity
EIB75_RS02095	COG0247	lactate metabolic process
EIB75_RS02100	COG0247	lactate metabolic process
EIB75_RS02100	COG2181	nitrate reductase activity
EIB75_RS02110	COG0438	transferase activity, transferring glycosyl groups
EIB75_RS02125	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EIB75_RS02130	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EIB75_RS02140	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EIB75_RS02145	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EIB75_RS02145	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EIB75_RS02180	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EIB75_RS02200	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EIB75_RS02220	COG0180	Tryptophanyl-tRNA synthetase
EIB75_RS02225	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EIB75_RS02240	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EIB75_RS02245	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EIB75_RS02260	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EIB75_RS02265	COG1278	Cold shock
EIB75_RS02300	COG1216	Glycosyl transferase, family 2
EIB75_RS02300	COG1442	glycosyl transferase family 8
EIB75_RS02305	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EIB75_RS02365	COG2321	neutral zinc metallopeptidase
EIB75_RS02370	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EIB75_RS02380	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EIB75_RS02395	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EIB75_RS02400	COG1611	Belongs to the LOG family
EIB75_RS02410	COG3385	transposase activity
EIB75_RS02455	COG2217	Heavy metal translocating P-type atpase
EIB75_RS02465	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EIB75_RS02475	COG0564	pseudouridine synthase activity
EIB75_RS02530	COG1607	acyl-coa hydrolase
EIB75_RS02535	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EIB75_RS02540	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EIB75_RS02575	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EIB75_RS02585	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EIB75_RS02590	COG1349	DNA-binding transcription factor activity
EIB75_RS02615	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EIB75_RS02615	COG1703	isobutyryl-CoA mutase activity
EIB75_RS02615	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EIB75_RS02630	COG0783	Belongs to the Dps family
EIB75_RS02635	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EIB75_RS02640	COG0049	tRNA binding
EIB75_RS02645	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EIB75_RS02650	COG0051	transcription antitermination factor activity, RNA binding
EIB75_RS02665	COG0051	transcription antitermination factor activity, RNA binding
EIB75_RS02690	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EIB75_RS02695	COG0088	Forms part of the polypeptide exit tunnel
EIB75_RS02705	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EIB75_RS02710	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EIB75_RS02715	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EIB75_RS02720	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EIB75_RS02725	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EIB75_RS02730	COG0255	Belongs to the universal ribosomal protein uL29 family
EIB75_RS02735	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EIB75_RS02740	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EIB75_RS02750	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EIB75_RS02755	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EIB75_RS02760	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EIB75_RS02765	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EIB75_RS02775	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EIB75_RS02780	COG1841	ribosomal large subunit assembly
EIB75_RS02785	COG0200	Binds to the 23S rRNA
EIB75_RS02795	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EIB75_RS02800	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EIB75_RS02805	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EIB75_RS02810	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EIB75_RS02815	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EIB75_RS02820	COG0202	RNA polymerase activity
EIB75_RS02825	COG0203	ribosomal protein L17
EIB75_RS02840	COG0813	purine-nucleoside phosphorylase activity
EIB75_RS02880	COG2852	Protein conserved in bacteria
EIB75_RS02895	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EIB75_RS02900	COG2137	regulation of response to DNA damage stimulus
EIB75_RS02925	COG2244	polysaccharide biosynthetic process
EIB75_RS02960	COG0463	Glycosyl transferase, family 2
EIB75_RS02965	COG0438	transferase activity, transferring glycosyl groups
EIB75_RS02970	COG0438	transferase activity, transferring glycosyl groups
EIB75_RS02975	COG0438	transferase activity, transferring glycosyl groups
EIB75_RS03035	COG0668	transmembrane transport
EIB75_RS03040	COG0045	succinate-CoA ligase (ADP-forming) activity
EIB75_RS03050	COG1132	(ABC) transporter
EIB75_RS03055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EIB75_RS03085	COG0632	four-way junction helicase activity
EIB75_RS03105	COG2353	YceI-like domain
EIB75_RS03110	COG3384	dioxygenase
EIB75_RS03115	COG0456	acetyltransferase
EIB75_RS03125	COG2986	histidine ammonia-lyase
EIB75_RS03140	COG4628	conserved protein (DUF2132)
EIB75_RS03145	COG3012	SEC-C Motif Domain Protein
EIB75_RS03150	COG0339	signal peptide processing
EIB75_RS03160	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EIB75_RS03165	COG1522	sequence-specific DNA binding
EIB75_RS03170	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EIB75_RS03175	COG0366	Alpha amylase catalytic
EIB75_RS03180	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EIB75_RS03185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EIB75_RS03195	COG1663	tetraacyldisaccharide 4'-kinase activity
EIB75_RS03200	COG1561	YicC-like family, N-terminal region
EIB75_RS03205	COG0194	GDP metabolic process
EIB75_RS03210	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EIB75_RS03230	COG1490	D-aminoacyl-tRNA deacylase activity
EIB75_RS03240	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EIB75_RS03250	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EIB75_RS03315	COG0281	malic enzyme
EIB75_RS03315	COG0280	phosphate acetyltransferase
EIB75_RS03320	COG0632	four-way junction helicase activity
EIB75_RS03330	COG0509	glycine decarboxylation via glycine cleavage system
EIB75_RS03400	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EIB75_RS03415	COG0616	signal peptide processing
EIB75_RS03425	COG2885	chlorophyll binding
EIB75_RS03435	COG0514	ATP-dependent DNA helicase (RecQ)
EIB75_RS03440	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EIB75_RS03455	COG0542	response to heat
EIB75_RS03460	COG1024	Enoyl-CoA hydratase
EIB75_RS03475	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EIB75_RS03485	COG0268	Binds directly to 16S ribosomal RNA
EIB75_RS03505	COG0251	oxidation-reduction process
EIB75_RS03515	COG0367	asparagine synthase
EIB75_RS03520	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EIB75_RS03540	COG2255	four-way junction helicase activity
EIB75_RS03545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EIB75_RS03550	COG0237	dephospho-CoA kinase activity
EIB75_RS03565	COG2261	transglycosylase associated protein
EIB75_RS03570	COG0552	protein localization to endoplasmic reticulum
EIB75_RS03580	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EIB75_RS03585	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EIB75_RS03595	COG1428	Deoxynucleoside kinase
EIB75_RS03610	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EIB75_RS03625	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EIB75_RS03645	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EIB75_RS03670	COG1192	Involved in chromosome partitioning
EIB75_RS03675	COG1475	DNA binding
EIB75_RS03685	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EIB75_RS03715	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EIB75_RS03720	COG0277	FAD linked oxidase domain protein
EIB75_RS03725	COG0300	oxidoreductase activity
EIB75_RS03735	COG1104	cysteine desulfurase activity
EIB75_RS03740	COG3118	belongs to the thioredoxin family
EIB75_RS03750	COG4974	Belongs to the 'phage' integrase family
EIB75_RS03775	COG0798	PFAM Bile acid sodium symporter
EIB75_RS03805	COG3781	membrane
EIB75_RS03815	COG1368	sulfuric ester hydrolase activity
EIB75_RS03820	COG1285	pathogenesis
EIB75_RS03825	COG2217	Heavy metal translocating P-type atpase
EIB75_RS03830	COG0671	phosphoesterase, PA-phosphatase related
EIB75_RS03835	COG2356	endonuclease I
EIB75_RS03905	COG1204	response to ionizing radiation
EIB75_RS03930	COG1250	3-hydroxyacyl-CoA dehydrogenase
EIB75_RS03940	COG4716	Myosin-crossreactive antigen
EIB75_RS03965	COG1846	Transcriptional regulator
EIB75_RS03970	COG0025	NhaP-type Na H and K H
EIB75_RS03975	COG3590	peptidase
EIB75_RS03990	COG0587	DNA-directed DNA polymerase activity
EIB75_RS04000	COG0018	arginyl-trna synthetase
EIB75_RS04005	COG0534	Mate efflux family protein
EIB75_RS04015	COG2234	aminopeptidase activity
EIB75_RS04035	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EIB75_RS04070	COG2226	methyltransferase
EIB75_RS04085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EIB75_RS04115	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EIB75_RS04115	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EIB75_RS04120	COG4206	TonB-dependent receptor
EIB75_RS04120	COG1629	transport
EIB75_RS04125	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EIB75_RS04135	COG1082	Xylose isomerase domain protein TIM barrel
EIB75_RS04145	COG0366	Alpha amylase catalytic
EIB75_RS04170	COG0028	Belongs to the TPP enzyme family
EIB75_RS04175	COG0440	acetolactate synthase activity
EIB75_RS04180	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EIB75_RS04185	COG1119	ATPase activity
EIB75_RS04190	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EIB75_RS04195	COG1741	Belongs to the pirin family
EIB75_RS04200	COG0151	Belongs to the GarS family
EIB75_RS04205	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EIB75_RS04205	COG0519	Catalyzes the synthesis of GMP from XMP
EIB75_RS04225	COG4654	Cytochrome c, class I
EIB75_RS04230	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
EIB75_RS04235	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EIB75_RS04240	COG0067	glutamate synthase
EIB75_RS04240	COG0069	glutamate synthase activity
EIB75_RS04240	COG0070	glutamate synthase
EIB75_RS04250	COG0187	DNA topoisomerase II activity
EIB75_RS04270	COG1078	dGTPase activity
EIB75_RS04275	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EIB75_RS04280	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EIB75_RS04280	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EIB75_RS04285	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EIB75_RS04290	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EIB75_RS04295	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EIB75_RS04300	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EIB75_RS04310	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EIB75_RS04325	COG0571	ribonuclease III activity
EIB75_RS04330	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EIB75_RS04335	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EIB75_RS04340	COG0302	gtp cyclohydrolase
EIB75_RS04345	COG0215	cysteine-tRNA ligase activity
EIB75_RS04355	COG1640	4-alpha-glucanotransferase
EIB75_RS04385	COG1528	Iron-storage protein
EIB75_RS04395	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EIB75_RS04400	COG4206	TonB-dependent receptor
EIB75_RS04400	COG1629	transport
EIB75_RS04420	COG4771	TonB-dependent receptor
EIB75_RS04430	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EIB75_RS04435	COG0356	it plays a direct role in the translocation of protons across the membrane
EIB75_RS04440	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EIB75_RS04445	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EIB75_RS04450	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EIB75_RS04455	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EIB75_RS04460	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EIB75_RS04465	COG1253	flavin adenine dinucleotide binding
EIB75_RS04475	COG2234	aminopeptidase activity
EIB75_RS04480	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EIB75_RS04485	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EIB75_RS04490	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EIB75_RS04495	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EIB75_RS04505	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EIB75_RS04510	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EIB75_RS04515	COG0066	3-isopropylmalate dehydratase activity
EIB75_RS04550	COG1960	acyl-CoA dehydrogenase activity
EIB75_RS04560	COG2732	(Barnase) inhibitor
EIB75_RS04565	COG0456	acetyltransferase
EIB75_RS04575	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EIB75_RS04595	COG1981	membrane
EIB75_RS04615	COG1702	phosphate starvation-inducible protein PhoH
EIB75_RS04625	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EIB75_RS04630	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EIB75_RS04645	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EIB75_RS04655	COG0484	heat shock protein binding
EIB75_RS04665	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EIB75_RS04675	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EIB75_RS04680	COG0527	aspartate kinase activity
EIB75_RS04700	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EIB75_RS04705	COG1181	Belongs to the D-alanine--D-alanine ligase family
EIB75_RS04715	COG0592	DNA-directed DNA polymerase activity
EIB75_RS04725	COG1051	belongs to the nudix hydrolase family
EIB75_RS04750	COG0470	DNA polymerase III
EIB75_RS04765	COG1309	transcriptional regulator
EIB75_RS04780	COG2814	Major facilitator Superfamily
EIB75_RS04785	COG1522	sequence-specific DNA binding
EIB75_RS04790	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EIB75_RS04800	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EIB75_RS04810	COG0300	oxidoreductase activity
EIB75_RS04855	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EIB75_RS04870	COG0598	Magnesium transport protein CorA
EIB75_RS04875	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EIB75_RS04880	COG1846	Transcriptional regulator
EIB75_RS04885	COG1764	response to oxidative stress
EIB75_RS04905	COG1760	l-serine dehydratase
EIB75_RS04920	COG0306	phosphate transporter
EIB75_RS04935	COG0084	hydrolase, TatD family'
EIB75_RS04940	COG0513	Belongs to the DEAD box helicase family
EIB75_RS04945	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EIB75_RS04950	COG0563	adenylate kinase activity
EIB75_RS04955	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EIB75_RS04965	COG0564	pseudouridine synthase activity
EIB75_RS04975	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EIB75_RS04980	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EIB75_RS05020	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EIB75_RS05040	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EIB75_RS05055	COG1007	ATP synthesis coupled electron transport
EIB75_RS05060	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EIB75_RS05065	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EIB75_RS05070	COG0713	ATP synthesis coupled electron transport
EIB75_RS05075	COG0839	Belongs to the complex I subunit 6 family
EIB75_RS05080	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EIB75_RS05085	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EIB75_RS05090	COG1034	ATP synthesis coupled electron transport
EIB75_RS05100	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EIB75_RS05115	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EIB75_RS05120	COG0649	NAD binding
EIB75_RS05125	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EIB75_RS05130	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EIB75_RS05135	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EIB75_RS05155	COG1739	Uncharacterized protein family UPF0029
EIB75_RS05160	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EIB75_RS05165	COG1408	metallophosphoesterase
EIB75_RS05175	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EIB75_RS05200	COG2226	methyltransferase
EIB75_RS05215	COG0284	orotidine-5'-phosphate decarboxylase activity
EIB75_RS05215	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EIB75_RS05220	COG0519	Catalyzes the synthesis of GMP from XMP
EIB75_RS05230	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EIB75_RS05240	COG0156	8-amino-7-oxononanoate synthase activity
EIB75_RS05260	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EIB75_RS05275	COG0791	NLP P60 protein
EIB75_RS05290	COG0037	tRNA processing
EIB75_RS05310	COG2267	carboxylic ester hydrolase activity
EIB75_RS05320	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EIB75_RS05325	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EIB75_RS05335	COG1012	belongs to the aldehyde dehydrogenase family
EIB75_RS05355	COG1368	sulfuric ester hydrolase activity
EIB75_RS05360	COG0791	NLP P60 protein
EIB75_RS05365	COG2171	N-acyltransferase activity
EIB75_RS05380	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EIB75_RS05385	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EIB75_RS05390	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EIB75_RS05445	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EIB75_RS05450	COG0295	cytidine deaminase activity
EIB75_RS05465	COG0318	PFAM AMP-dependent synthetase and ligase
EIB75_RS05505	COG2226	methyltransferase
EIB75_RS05540	COG2274	protein secretion by the type I secretion system
EIB75_RS05545	COG0667	Aldo Keto reductase
EIB75_RS05610	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EIB75_RS05615	COG0205	6-phosphofructokinase activity
EIB75_RS05625	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
EIB75_RS05670	COG2264	protein methyltransferase activity
EIB75_RS05675	COG3023	N-Acetylmuramoyl-L-alanine amidase
EIB75_RS05700	COG3279	Response regulator of the LytR AlgR family
EIB75_RS05705	COG2972	Histidine kinase
EIB75_RS05775	COG2204	response regulator
EIB75_RS05785	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EIB75_RS05795	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EIB75_RS05805	COG2205	protein histidine kinase activity
EIB75_RS05810	COG5002	protein histidine kinase activity
EIB75_RS05840	COG0753	catalase activity
EIB75_RS05855	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EIB75_RS05880	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EIB75_RS05895	COG0012	GTP binding
EIB75_RS05945	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EIB75_RS05965	COG0714	Associated with various cellular activities
EIB75_RS05990	COG2304	oxidoreductase activity
EIB75_RS05995	COG2304	oxidoreductase activity
EIB75_RS06010	COG0492	ferredoxin-NADP+ reductase activity
EIB75_RS06030	COG0745	RESPONSE REGULATOR receiver
EIB75_RS06070	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EIB75_RS06090	COG4095	Psort location CytoplasmicMembrane, score
EIB75_RS06105	COG1793	dna ligase
EIB75_RS06110	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EIB75_RS06110	COG1793	dna ligase
EIB75_RS06115	COG3871	stress protein (general stress protein 26)
EIB75_RS06120	COG1028	Short-chain dehydrogenase reductase Sdr
EIB75_RS06125	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EIB75_RS06150	COG1959	2 iron, 2 sulfur cluster binding
EIB75_RS06160	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EIB75_RS06185	COG1132	(ABC) transporter
EIB75_RS06195	COG2873	o-acetylhomoserine
EIB75_RS06205	COG3153	acetyltransferase
EIB75_RS06205	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EIB75_RS06220	COG2217	Heavy metal translocating P-type atpase
EIB75_RS06255	COG4989	oxidoreductase activity
EIB75_RS06260	COG0724	RNA recognition motif
EIB75_RS06280	COG0508	dehydrogenase complex catalyzes the overall conversion of
EIB75_RS06300	COG1674	ftsk spoiiie
EIB75_RS06305	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EIB75_RS06305	COG1333	cytochrome c biogenesis protein
EIB75_RS06335	COG2095	MarC family integral membrane protein
EIB75_RS06350	COG1022	Amp-dependent synthetase and ligase
EIB75_RS06355	COG1022	Amp-dependent synthetase and ligase
EIB75_RS06360	COG1960	acyl-CoA dehydrogenase activity
EIB75_RS06375	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EIB75_RS06385	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EIB75_RS06390	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EIB75_RS06395	COG2814	Major facilitator Superfamily
EIB75_RS06405	COG0124	histidyl-tRNA synthetase
EIB75_RS06410	COG2996	Protein conserved in bacteria
EIB75_RS06415	COG1090	epimerase
EIB75_RS06430	COG4115	mRNA cleavage
EIB75_RS06435	COG2161	toxin-antitoxin pair type II binding
EIB75_RS06460	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EIB75_RS06465	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EIB75_RS06470	COG0105	UTP biosynthetic process
EIB75_RS06475	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EIB75_RS06480	COG1363	Peptidase, m42
EIB75_RS06495	COG1272	protein, Hemolysin III
EIB75_RS06500	COG0679	Auxin Efflux Carrier
EIB75_RS06505	COG1272	protein, Hemolysin III
EIB75_RS06510	COG2027	D-alanyl-D-alanine carboxypeptidase
EIB75_RS06520	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EIB75_RS06525	COG0656	L-ascorbic acid biosynthetic process
EIB75_RS06535	COG0745	RESPONSE REGULATOR receiver
EIB75_RS06540	COG5002	protein histidine kinase activity
EIB75_RS06550	COG0531	amino acid
EIB75_RS06555	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EIB75_RS06600	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EIB75_RS06615	COG0243	molybdopterin cofactor binding
EIB75_RS06620	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EIB75_RS06620	COG0493	'glutamate synthase
EIB75_RS06645	COG0303	'Molybdopterin
EIB75_RS06655	COG0746	molybdenum cofactor guanylyltransferase activity
EIB75_RS06665	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EIB75_RS06670	COG0314	molybdopterin synthase activity
EIB75_RS06675	COG0521	Mo-molybdopterin cofactor biosynthetic process
EIB75_RS06675	COG0315	cyclic pyranopterin monophosphate synthase activity
EIB75_RS06685	COG1959	2 iron, 2 sulfur cluster binding
EIB75_RS06700	COG1999	signal sequence binding
EIB75_RS06705	COG4654	Cytochrome c, class I
EIB75_RS06710	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EIB75_RS06725	COG3189	MarR family transcriptional regulator
EIB75_RS06745	COG3842	ATPase activity
EIB75_RS06780	COG2801	Transposase and inactivated derivatives
EIB75_RS06780	COG3415	Transposase
EIB75_RS06830	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EIB75_RS06850	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EIB75_RS06855	COG2706	6-phosphogluconolactonase activity
EIB75_RS06865	COG2706	6-phosphogluconolactonase activity
EIB75_RS06870	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EIB75_RS06885	COG0668	transmembrane transport
EIB75_RS06890	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EIB75_RS06895	COG0596	Alpha beta hydrolase
EIB75_RS06920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EIB75_RS06925	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EIB75_RS06925	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EIB75_RS06935	COG0484	heat shock protein binding
EIB75_RS06940	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EIB75_RS06960	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EIB75_RS06995	COG0629	single-stranded DNA binding
EIB75_RS07015	COG0233	cytoplasmic translational termination
EIB75_RS07020	COG0528	UMP kinase activity
EIB75_RS07030	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EIB75_RS07050	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EIB75_RS07070	COG0508	dehydrogenase complex catalyzes the overall conversion of
EIB75_RS07085	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EIB75_RS07095	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EIB75_RS07095	COG1605	Chorismate mutase
EIB75_RS07100	COG1162	GTPase activity
EIB75_RS07115	COG0442	prolyl-tRNA aminoacylation
EIB75_RS07125	COG1914	H( )-stimulated, divalent metal cation uptake system
EIB75_RS07130	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EIB75_RS07150	COG1185	polyribonucleotide nucleotidyltransferase activity
EIB75_RS07170	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EIB75_RS07185	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EIB75_RS07215	COG0587	DNA-directed DNA polymerase activity
EIB75_RS07220	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EIB75_RS07230	COG3292	Two component regulator propeller
EIB75_RS07230	COG2205	protein histidine kinase activity
EIB75_RS07230	COG0745	RESPONSE REGULATOR receiver
EIB75_RS07235	COG2814	Major facilitator Superfamily
EIB75_RS07240	COG1621	beta-fructofuranosidase activity
EIB75_RS07245	COG4206	TonB-dependent receptor
EIB75_RS07245	COG1629	transport
EIB75_RS07250	COG0702	epimerase
EIB75_RS07305	COG1266	CAAX protease self-immunity
EIB75_RS07310	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EIB75_RS07315	COG1234	tRNA 3'-trailer cleavage
EIB75_RS07320	COG0022	dehydrogenase e1 component
EIB75_RS07330	COG1595	DNA-templated transcription, initiation
EIB75_RS07335	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EIB75_RS07340	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EIB75_RS07350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EIB75_RS07390	COG1575	Belongs to the MenA family. Type 1 subfamily
EIB75_RS07395	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EIB75_RS07420	COG0463	Glycosyl transferase, family 2
EIB75_RS07435	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EIB75_RS07440	COG0436	Aminotransferase
EIB75_RS07455	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EIB75_RS07470	COG1472	Belongs to the glycosyl hydrolase 3 family
EIB75_RS07480	COG0196	riboflavin kinase activity
EIB75_RS07485	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EIB75_RS07490	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EIB75_RS07525	COG5002	protein histidine kinase activity
EIB75_RS07530	COG0784	Response regulator, receiver
EIB75_RS07530	COG2205	protein histidine kinase activity
EIB75_RS07535	COG0745	RESPONSE REGULATOR receiver
EIB75_RS07540	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EIB75_RS07550	COG2205	protein histidine kinase activity
EIB75_RS07550	COG0784	Response regulator, receiver
EIB75_RS07605	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EIB75_RS07605	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EIB75_RS07630	COG2239	Acts as a magnesium transporter
EIB75_RS07635	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EIB75_RS07650	COG2003	Belongs to the UPF0758 family
EIB75_RS07655	COG1136	(ABC) transporter
EIB75_RS07675	COG1215	transferase activity, transferring glycosyl groups
EIB75_RS07690	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EIB75_RS07715	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EIB75_RS07765	COG1609	Transcriptional regulator
EIB75_RS07915	COG1192	Involved in chromosome partitioning
EIB75_RS07940	COG0484	heat shock protein binding
EIB75_RS07995	COG0739	heme binding
EIB75_RS08045	COG2890	protein-(glutamine-N5) methyltransferase activity
EIB75_RS08105	COG1505	serine-type exopeptidase activity
EIB75_RS08230	COG0346	lactoylglutathione lyase activity
EIB75_RS08235	COG0149	triose-phosphate isomerase activity
EIB75_RS08260	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EIB75_RS08275	COG0360	Binds together with S18 to 16S ribosomal RNA
EIB75_RS08280	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EIB75_RS08285	COG0359	binds to the 23S rRNA
EIB75_RS08305	COG2176	DNA-directed DNA polymerase activity
EIB75_RS08310	COG2967	ApaG domain
EIB75_RS08395	COG1960	acyl-CoA dehydrogenase activity
EIB75_RS08415	COG0357	Ribosomal RNA small subunit methyltransferase G
EIB75_RS08425	COG0436	Aminotransferase
EIB75_RS08430	COG0450	alkyl hydroperoxide reductase
EIB75_RS08435	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EIB75_RS08475	COG0116	Belongs to the methyltransferase superfamily
EIB75_RS08485	COG0028	Belongs to the TPP enzyme family
EIB75_RS08495	COG2207	Transcriptional regulator
EIB75_RS08500	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EIB75_RS08505	COG1649	PFAM Uncharacterised BCR, COG1649
EIB75_RS08510	COG0788	formyltetrahydrofolate deformylase activity
EIB75_RS08515	COG1217	gtp-binding protein TYPA
EIB75_RS08525	COG0477	Major facilitator Superfamily
EIB75_RS08530	COG2957	Belongs to the agmatine deiminase family
EIB75_RS08545	COG1607	acyl-coa hydrolase
EIB75_RS08550	COG4717	serine-type aminopeptidase activity
EIB75_RS08570	COG0612	Peptidase, M16
EIB75_RS08800	COG0735	belongs to the Fur family
EIB75_RS08835	COG2217	Heavy metal translocating P-type atpase
EIB75_RS08860	COG2217	Heavy metal translocating P-type atpase
EIB75_RS08885	COG2132	Multicopper oxidase
EIB75_RS08895	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EIB75_RS08945	COG2814	Major facilitator Superfamily
EIB75_RS08955	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EIB75_RS08960	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EIB75_RS08965	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EIB75_RS08980	COG4251	negative regulation of phosphorylation
EIB75_RS08990	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EIB75_RS09000	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EIB75_RS09005	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EIB75_RS09005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EIB75_RS09010	COG0494	nUDIX hydrolase
EIB75_RS09015	COG0438	transferase activity, transferring glycosyl groups
EIB75_RS09020	COG0514	ATP-dependent DNA helicase (RecQ)
EIB75_RS09025	COG0517	IMP dehydrogenase activity
EIB75_RS09025	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EIB75_RS09030	COG0805	protein transport
EIB75_RS09035	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EIB75_RS09055	COG1187	pseudouridine synthase activity
EIB75_RS09065	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EIB75_RS09065	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EIB75_RS09075	COG0572	uridine kinase
EIB75_RS09080	COG2949	membrane
EIB75_RS09095	COG3118	belongs to the thioredoxin family
EIB75_RS09100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EIB75_RS09110	COG1120	ATPase activity
EIB75_RS09120	COG1250	3-hydroxyacyl-CoA dehydrogenase
EIB75_RS09120	COG1024	Enoyl-CoA hydratase
EIB75_RS09130	COG0183	Belongs to the thiolase family
EIB75_RS09140	COG1960	acyl-CoA dehydrogenase activity
EIB75_RS09170	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EIB75_RS09175	COG0512	Glutamine amidotransferase of anthranilate synthase
EIB75_RS09175	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EIB75_RS09180	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EIB75_RS09185	COG0134	indole-3-glycerol-phosphate synthase activity
EIB75_RS09190	COG0135	phosphoribosylanthranilate isomerase activity
EIB75_RS09195	COG0133	tryptophan synthase activity
EIB75_RS09200	COG0159	tryptophan synthase activity
EIB75_RS09215	COG1950	PFAM Membrane protein of
EIB75_RS09270	COG0321	lipoyl(octanoyl) transferase activity
EIB75_RS09275	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EIB75_RS09340	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EIB75_RS09360	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EIB75_RS09365	COG0586	Pfam SNARE associated Golgi protein
EIB75_RS09380	COG1012	belongs to the aldehyde dehydrogenase family
EIB75_RS09385	COG1335	isochorismatase
EIB75_RS09390	COG2323	membrane
EIB75_RS09405	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EIB75_RS09410	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EIB75_RS09425	COG0693	protein deglycase activity
EIB75_RS09450	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EIB75_RS09460	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EIB75_RS09470	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EIB75_RS09490	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EIB75_RS09495	COG1999	signal sequence binding
EIB75_RS09510	COG2356	endonuclease I
EIB75_RS09515	COG0482	sulfurtransferase activity
EIB75_RS09530	COG1858	cytochrome C peroxidase
EIB75_RS09555	COG3685	Protein conserved in bacteria
EIB75_RS09625	COG0702	epimerase
EIB75_RS09630	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EIB75_RS09630	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EIB75_RS09650	COG3046	protein related to deoxyribodipyrimidine photolyase
EIB75_RS09660	COG1028	Short-chain dehydrogenase reductase Sdr
EIB75_RS09670	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EIB75_RS09690	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EIB75_RS09710	COG0006	proline dipeptidase activity
EIB75_RS09735	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EIB75_RS09760	COG0484	heat shock protein binding
EIB75_RS09770	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EIB75_RS09775	COG0297	glycogen (starch) synthase activity
EIB75_RS09780	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EIB75_RS09790	COG4974	Belongs to the 'phage' integrase family
EIB75_RS09815	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EIB75_RS09820	COG0517	IMP dehydrogenase activity
EIB75_RS09825	COG4974	Belongs to the 'phage' integrase family
EIB75_RS09845	COG4974	Belongs to the 'phage' integrase family
EIB75_RS09865	COG4974	Belongs to the 'phage' integrase family
EIB75_RS09870	COG0517	IMP dehydrogenase activity
EIB75_RS09875	COG0517	IMP dehydrogenase activity
EIB75_RS09880	COG4974	Belongs to the 'phage' integrase family
EIB75_RS09900	COG1131	(ABC) transporter
EIB75_RS09925	COG4974	Belongs to the 'phage' integrase family
EIB75_RS09940	COG0789	Transcriptional regulator
EIB75_RS09945	COG0517	IMP dehydrogenase activity
EIB75_RS09950	COG4974	Belongs to the 'phage' integrase family
EIB75_RS09965	COG0604	alcohol dehydrogenase
EIB75_RS10085	COG2197	response regulator
EIB75_RS10090	COG0386	Belongs to the glutathione peroxidase family
EIB75_RS10095	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EIB75_RS10100	COG2824	Alkylphosphonate utilization operon protein PhnA
EIB75_RS10105	COG3842	ATPase activity
EIB75_RS10115	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EIB75_RS10130	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EIB75_RS10135	COG0745	RESPONSE REGULATOR receiver
EIB75_RS10140	COG5002	protein histidine kinase activity
EIB75_RS10185	COG2270	Major facilitator Superfamily
EIB75_RS10190	COG0183	Belongs to the thiolase family
EIB75_RS10220	COG1595	DNA-templated transcription, initiation
EIB75_RS10225	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EIB75_RS10240	COG0508	dehydrogenase complex catalyzes the overall conversion of
EIB75_RS10255	COG1607	acyl-coa hydrolase
EIB75_RS10260	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EIB75_RS10290	COG1012	belongs to the aldehyde dehydrogenase family
EIB75_RS10300	COG0561	phosphatase activity
EIB75_RS10315	COG0252	asparaginase activity
EIB75_RS10320	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EIB75_RS10340	COG0531	amino acid
EIB75_RS10350	COG0077	Prephenate dehydratase
EIB75_RS10365	COG1247	-acetyltransferase
EIB75_RS10370	COG0626	cystathionine gamma-synthase activity
EIB75_RS10385	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EIB75_RS10395	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EIB75_RS10395	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EIB75_RS10405	COG2226	methyltransferase
EIB75_RS10430	COG1418	mRNA catabolic process
EIB75_RS10435	COG0071	Belongs to the small heat shock protein (HSP20) family
EIB75_RS10440	COG0405	Gamma-glutamyltransferase
EIB75_RS10450	COG3781	membrane
EIB75_RS10470	COG3385	transposase activity
EIB75_RS10475	COG2183	response to ionizing radiation
EIB75_RS10475	COG0539	negative regulation of cytoplasmic translation
EIB75_RS10480	COG3421	Type III restriction
EIB75_RS10490	COG2189	Belongs to the N(4) N(6)-methyltransferase family
EIB75_RS10495	COG0513	Belongs to the DEAD box helicase family
EIB75_RS10510	COG1187	pseudouridine synthase activity
EIB75_RS10520	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EIB75_RS10525	COG1968	undecaprenyl-diphosphatase activity
EIB75_RS10535	COG2177	Part of the ABC transporter FtsEX involved in
EIB75_RS10545	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EIB75_RS10545	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EIB75_RS10550	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EIB75_RS10825	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EIB75_RS10825	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EIB75_RS10830	COG3118	belongs to the thioredoxin family
EIB75_RS10865	COG1770	oligopeptidase
EIB75_RS10890	COG0792	nuclease activity
EIB75_RS10895	COG1619	proteins homologs of microcin C7 resistance protein MccF
EIB75_RS10905	COG0557	exoribonuclease II activity
EIB75_RS10915	COG0698	ribose 5-phosphate isomerase
EIB75_RS10925	COG0126	phosphoglycerate kinase activity
EIB75_RS10935	COG0445	tRNA wobble uridine modification
EIB75_RS10940	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EIB75_RS10950	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EIB75_RS10965	COG1435	thymidine kinase activity
EIB75_RS10975	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EIB75_RS10990	COG1028	Short-chain dehydrogenase reductase Sdr
EIB75_RS10995	COG0247	lactate metabolic process
EIB75_RS11030	COG0556	nucleotide-excision repair
EIB75_RS11050	COG0628	permease
EIB75_RS11065	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EIB75_RS11075	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EIB75_RS11090	COG3275	phosphorelay sensor kinase activity
EIB75_RS11115	COG0482	sulfurtransferase activity
EIB75_RS11125	COG0542	response to heat
EIB75_RS11145	COG1703	isobutyryl-CoA mutase activity
EIB75_RS11155	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EIB75_RS11155	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EIB75_RS11165	COG0793	Belongs to the peptidase S41A family
EIB75_RS11170	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EIB75_RS11190	COG2176	DNA-directed DNA polymerase activity
EIB75_RS11195	COG0433	COG0433 Predicted ATPase
EIB75_RS11200	COG3781	membrane
EIB75_RS11215	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EIB75_RS11220	COG0191	fructose-bisphosphate aldolase activity
EIB75_RS11225	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EIB75_RS11235	COG1464	Belongs to the NlpA lipoprotein family
EIB75_RS11240	COG0700	Nucleoside recognition
EIB75_RS11255	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EIB75_RS11260	COG2153	protein acetylation
EIB75_RS11285	COG0606	chelatase, subunit chli
EIB75_RS11290	COG0328	RNA-DNA hybrid ribonuclease activity
EIB75_RS11300	COG0305	Participates in initiation and elongation during chromosome replication
EIB75_RS11310	COG1131	(ABC) transporter
EIB75_RS11315	COG2076	Multidrug Resistance protein
EIB75_RS11335	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EIB75_RS11380	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EIB75_RS11400	COG3033	Beta-eliminating lyase
EIB75_RS11410	COG0424	maF-like protein
EIB75_RS11415	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EIB75_RS11440	COG0758	DNA mediated transformation
EIB75_RS11460	COG1940	carbohydrate kinase activity
EIB75_RS11470	COG4773	Receptor
EIB75_RS11480	COG0653	protein targeting
EIB75_RS11525	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EIB75_RS11540	COG0193	aminoacyl-tRNA hydrolase activity
EIB75_RS11560	COG0288	reversible hydration of carbon dioxide
EIB75_RS11585	COG0438	transferase activity, transferring glycosyl groups
EIB75_RS11600	COG1215	transferase activity, transferring glycosyl groups
EIB75_RS11610	COG1216	Glycosyl transferase, family 2
EIB75_RS11615	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EIB75_RS11620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EIB75_RS11640	COG0463	Glycosyl transferase, family 2
EIB75_RS11685	COG0779	Required for maturation of 30S ribosomal subunits
EIB75_RS11690	COG0195	Participates in both transcription termination and antitermination
EIB75_RS11690	COG2251	uridine kinase activity
EIB75_RS11695	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EIB75_RS11700	COG4771	TonB-dependent receptor
EIB75_RS11720	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EIB75_RS11765	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EIB75_RS11770	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EIB75_RS11795	COG2234	aminopeptidase activity
EIB75_RS11800	COG1132	(ABC) transporter
EIB75_RS11810	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EIB75_RS11830	COG0719	Fe-S assembly protein
EIB75_RS11835	COG0396	ATPase activity
EIB75_RS11845	COG0719	Fe-S assembly protein
EIB75_RS11850	COG0316	Belongs to the HesB IscA family
EIB75_RS11875	COG4804	nuclease activity
EIB75_RS11880	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EIB75_RS11905	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EIB75_RS11910	COG0527	aspartate kinase activity
EIB75_RS11910	COG0460	homoserine dehydrogenase
EIB75_RS11930	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EIB75_RS11935	COG1228	amidohydrolase
EIB75_RS11945	COG0546	phosphoglycolate phosphatase activity
EIB75_RS11960	COG0436	Aminotransferase
EIB75_RS11965	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EIB75_RS11975	COG1051	belongs to the nudix hydrolase family
EIB75_RS11980	COG4974	Belongs to the 'phage' integrase family
EIB75_RS11990	COG1024	Enoyl-CoA hydratase
EIB75_RS11995	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EIB75_RS12000	COG0148	phosphopyruvate hydratase activity
EIB75_RS12075	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EIB75_RS12080	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EIB75_RS12085	COG0612	Peptidase, M16
EIB75_RS12095	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EIB75_RS12105	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EIB75_RS12145	COG2814	Major facilitator Superfamily
EIB75_RS12150	COG2132	Multicopper oxidase
EIB75_RS12165	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EIB75_RS12175	COG1764	response to oxidative stress
EIB75_RS12185	COG2217	Heavy metal translocating P-type atpase
EIB75_RS12235	COG2963	transposase activity
EIB75_RS12250	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EIB75_RS12250	COG1017	nitric oxide dioxygenase activity
EIB75_RS12265	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
EIB75_RS12285	COG2217	Heavy metal translocating P-type atpase
EIB75_RS12315	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EIB75_RS12315	COG0551	DNA topoisomerase type I activity
EIB75_RS12350	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EIB75_RS12560	COG4974	Belongs to the 'phage' integrase family
EIB75_RS12575	COG0516	GMP reductase activity
EIB75_RS12575	COG0517	IMP dehydrogenase activity
EIB75_RS12585	COG0300	oxidoreductase activity
EIB75_RS12610	COG0022	dehydrogenase e1 component
EIB75_RS12615	COG1309	transcriptional regulator
EIB75_RS12620	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EIB75_RS12625	COG3396	Phenylacetate-CoA oxygenase
EIB75_RS12630	COG3460	Phenylacetate-CoA oxygenase
EIB75_RS12640	COG2151	metal-sulfur cluster biosynthetic enzyme
EIB75_RS12645	COG1250	3-hydroxyacyl-CoA dehydrogenase
EIB75_RS12655	COG0183	Belongs to the thiolase family
EIB75_RS12665	COG1012	belongs to the aldehyde dehydrogenase family
EIB75_RS12665	COG2030	dehydratase
EIB75_RS12680	COG0254	rRNA binding
EIB75_RS12770	COG1595	DNA-templated transcription, initiation
EIB75_RS12790	COG1862	Preprotein translocase
EIB75_RS12810	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EIB75_RS12850	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EIB75_RS12885	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EIB75_RS12900	COG0658	competence protein
EIB75_RS12900	COG2333	competence protein COMEC
EIB75_RS12910	COG0248	Ppx GppA phosphatase
EIB75_RS12915	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EIB75_RS12920	COG0443	Heat shock 70 kDa protein
EIB75_RS12930	COG4974	Belongs to the 'phage' integrase family
EIB75_RS13000	COG3620	sequence-specific DNA binding
EIB75_RS13010	COG4974	Belongs to the 'phage' integrase family
EIB75_RS13015	COG4974	Belongs to the 'phage' integrase family
EIB75_RS13030	COG3620	sequence-specific DNA binding
EIB75_RS13040	COG4974	Belongs to the 'phage' integrase family
EIB75_RS13045	COG4974	Belongs to the 'phage' integrase family
EIB75_RS13065	COG0358	DNA primase activity
EIB75_RS13075	COG4974	Belongs to the 'phage' integrase family
EIB75_RS13080	COG4974	Belongs to the 'phage' integrase family
EIB75_RS13110	COG4974	Belongs to the 'phage' integrase family
EIB75_RS13150	COG1629	transport
EIB75_RS13160	COG4946	Tricorn protease homolog
EIB75_RS13160	COG1506	peptidase
EIB75_RS13160	COG0823	Involved in the tonB-independent uptake of proteins
EIB75_RS13275	COG0739	heme binding
EIB75_RS13285	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EIB75_RS13290	COG3339	Conserved Protein
EIB75_RS13295	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EIB75_RS13300	COG0489	protein tyrosine kinase activity
EIB75_RS13305	COG1301	dicarboxylic acid transport
EIB75_RS13335	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EIB75_RS13350	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EIB75_RS13355	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EIB75_RS13360	COG0052	Belongs to the universal ribosomal protein uS2 family
EIB75_RS13365	COG0825	malonyl-CoA metabolic process
EIB75_RS13370	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EIB75_RS13400	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EIB75_RS13405	COG0439	Biotin carboxylase
EIB75_RS13415	COG0511	ligase activity, forming carbon-carbon bonds
EIB75_RS13420	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EIB75_RS13435	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EIB75_RS13440	COG0307	riboflavin synthase, alpha
EIB75_RS13445	COG5000	phosphorelay sensor kinase activity
EIB75_RS13450	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EIB75_RS13455	COG2884	Cell division ATP-binding protein ftsE
EIB75_RS13460	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EIB75_RS13475	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EIB75_RS13475	COG1519	Transferase
EIB75_RS13490	COG0495	leucyl-tRNA aminoacylation
EIB75_RS13505	COG0848	biopolymer transport protein
EIB75_RS13530	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EIB75_RS13550	COG1132	(ABC) transporter
EIB75_RS13555	COG0579	oxidoreductase
EIB75_RS13565	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EIB75_RS13575	COG0737	Belongs to the 5'-nucleotidase family
EIB75_RS13600	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EIB75_RS13605	COG4232	protein-disulfide reductase activity
EIB75_RS13615	COG3104	oligopeptide transport
EIB75_RS13625	COG3104	oligopeptide transport
EIB75_RS13640	COG1506	peptidase
EIB75_RS13640	COG0823	Involved in the tonB-independent uptake of proteins
EIB75_RS13645	COG1054	Belongs to the UPF0176 family
EIB75_RS13650	COG0826	peptidase U32
EIB75_RS13685	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EIB75_RS13690	COG1137	ATPase activity
EIB75_RS13700	COG2096	Adenosyltransferase
EIB75_RS13730	COG1733	regulation of RNA biosynthetic process
EIB75_RS13740	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EIB75_RS13760	COG0450	alkyl hydroperoxide reductase
EIB75_RS13770	COG1472	Belongs to the glycosyl hydrolase 3 family
EIB75_RS13780	COG0438	transferase activity, transferring glycosyl groups
EIB75_RS13800	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EIB75_RS13805	COG1053	succinate dehydrogenase
EIB75_RS13820	COG3590	peptidase
EIB75_RS13835	COG0017	Asparaginyl-tRNA synthetase
EIB75_RS13840	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EIB75_RS13845	COG0228	four-way junction DNA binding
EIB75_RS13850	COG0415	Belongs to the DNA photolyase family
EIB75_RS13865	COG0336	Belongs to the RNA methyltransferase TrmD family
EIB75_RS13870	COG1252	NADH dehydrogenase
EIB75_RS13880	COG4206	TonB-dependent receptor
EIB75_RS13885	COG1194	a g-specific adenine glycosylase
EIB75_RS13890	COG0776	regulation of translation
EIB75_RS13895	COG1530	ribonuclease E activity
EIB75_RS13900	COG0745	RESPONSE REGULATOR receiver
EIB75_RS13905	COG0708	Exodeoxyribonuclease III
EIB75_RS13925	COG0322	excinuclease ABC activity
EIB75_RS13950	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EIB75_RS13975	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EIB75_RS13990	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EIB75_RS14005	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EIB75_RS14010	COG1028	Short-chain dehydrogenase reductase Sdr
EIB75_RS14015	COG0101	tRNA pseudouridine synthase activity
EIB75_RS14020	COG1132	(ABC) transporter
EIB75_RS14050	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EIB75_RS14060	COG0427	acetyl-CoA hydrolase
EIB75_RS14070	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
EIB75_RS14075	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EIB75_RS14085	COG0745	RESPONSE REGULATOR receiver
EIB75_RS14090	COG5002	protein histidine kinase activity
EIB75_RS14095	COG1368	sulfuric ester hydrolase activity
EIB75_RS14110	COG0671	phosphoesterase, PA-phosphatase related
EIB75_RS14120	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EIB75_RS14120	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EIB75_RS14140	COG1678	Uncharacterized ACR, COG1678
EIB75_RS14145	COG0259	pyridoxamine-phosphate oxidase activity
EIB75_RS14150	COG2247	cell wall binding repeat
EIB75_RS14150	COG0860	N-Acetylmuramoyl-L-alanine amidase
EIB75_RS14155	COG0140	phosphoribosyl-ATP diphosphatase activity
EIB75_RS14155	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EIB75_RS14160	COG0107	imidazoleglycerol-phosphate synthase activity
EIB75_RS14165	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EIB75_RS14175	COG0131	Imidazoleglycerol-phosphate dehydratase
EIB75_RS14180	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EIB75_RS14185	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EIB75_RS14190	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EIB75_RS14210	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EIB75_RS14225	COG3158	transport of potassium into the cell
EIB75_RS14250	COG2204	response regulator
EIB75_RS14280	COG1136	(ABC) transporter
EIB75_RS14280	COG0577	efflux transmembrane transporter activity
EIB75_RS14310	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EIB75_RS14330	COG1136	(ABC) transporter
EIB75_RS14340	COG1136	(ABC) transporter
EIB75_RS14340	COG0577	efflux transmembrane transporter activity
EIB75_RS14345	COG1136	(ABC) transporter
EIB75_RS14345	COG0577	efflux transmembrane transporter activity
EIB75_RS14350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EIB75_RS14360	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EIB75_RS14365	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EIB75_RS14375	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EIB75_RS14385	COG0004	ammonium transporteR
EIB75_RS14395	COG3425	synthase
EIB75_RS14405	COG1012	belongs to the aldehyde dehydrogenase family
EIB75_RS14420	COG1301	dicarboxylic acid transport
EIB75_RS14425	COG1058	Belongs to the CinA family
EIB75_RS14425	COG1546	Belongs to the CinA family
EIB75_RS14435	COG2814	Major facilitator Superfamily
EIB75_RS14440	COG0667	Aldo Keto reductase
EIB75_RS14470	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EIB75_RS14490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EIB75_RS14505	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EIB75_RS14515	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EIB75_RS14520	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EIB75_RS14540	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EIB75_RS14545	COG0297	glycogen (starch) synthase activity
EIB75_RS14555	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EIB75_RS14560	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EIB75_RS14585	COG0175	sulfate reduction
EIB75_RS14590	COG0175	sulfate reduction
EIB75_RS14600	COG0730	response to heat
EIB75_RS14615	COG4774	siderophore transport
EIB75_RS14620	COG0488	(ABC) transporter
EIB75_RS14665	COG0179	Fumarylacetoacetate (FAA) hydrolase
EIB75_RS14680	COG1183	phosphatidylcholine synthase activity
EIB75_RS14690	COG0463	Glycosyl transferase, family 2
EIB75_RS14705	COG0022	dehydrogenase e1 component
EIB75_RS14705	COG0508	dehydrogenase complex catalyzes the overall conversion of
EIB75_RS14710	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EIB75_RS14715	COG4974	Belongs to the 'phage' integrase family
EIB75_RS14760	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EIB75_RS14790	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EIB75_RS14795	COG0081	regulation of translation
EIB75_RS14800	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EIB75_RS14805	COG0222	ribosome binding
EIB75_RS14855	COG0085	RNA polymerase activity
EIB75_RS14860	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EIB75_RS14875	COG1064	alcohol dehydrogenase
EIB75_RS14895	COG0113	porphobilinogen synthase activity
EIB75_RS14905	COG1418	mRNA catabolic process
EIB75_RS14915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EIB75_RS14925	COG0525	valine-tRNA ligase activity
EIB75_RS14935	COG2326	polyphosphate kinase activity
EIB75_RS14940	COG1012	belongs to the aldehyde dehydrogenase family
EIB75_RS14950	COG0492	ferredoxin-NADP+ reductase activity
EIB75_RS14965	COG3040	lipid binding
EIB75_RS14970	COG0633	Ferredoxin
EIB75_RS14975	COG0492	ferredoxin-NADP+ reductase activity
EIB75_RS15030	COG1250	3-hydroxyacyl-CoA dehydrogenase
EIB75_RS15045	COG0270	DNA (cytosine-5-)-methyltransferase activity
EIB75_RS15060	COG0673	inositol 2-dehydrogenase activity
EIB75_RS15065	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EIB75_RS15070	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EIB75_RS15075	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EIB75_RS15080	COG3956	TIGRFAM MazG family protein
EIB75_RS15115	COG0488	(ABC) transporter
EIB75_RS15130	COG1528	Iron-storage protein
EIB75_RS15135	COG1629	transport
EIB75_RS15140	COG0702	epimerase
EIB75_RS15175	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EIB75_RS15175	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EIB75_RS15185	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EIB75_RS15190	COG0671	phosphoesterase, PA-phosphatase related
EIB75_RS15195	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EIB75_RS15200	COG1295	ribonuclease BN
EIB75_RS15205	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EIB75_RS15210	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EIB75_RS15215	COG2308	Evidence 4 Homologs of previously reported genes of
EIB75_RS15225	COG1305	Transglutaminase-like
EIB75_RS15235	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EIB75_RS15245	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EIB75_RS15255	COG0436	Aminotransferase
EIB75_RS15280	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EIB75_RS15315	COG1160	GTP binding
EIB75_RS15320	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EIB75_RS15325	COG1040	competence protein
EIB75_RS15340	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EIB75_RS15345	COG2224	Isocitrate lyase
EIB75_RS15375	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EIB75_RS15385	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EIB75_RS15405	COG2244	polysaccharide biosynthetic process
EIB75_RS15465	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EIB75_RS15470	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EIB75_RS15475	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EIB75_RS15490	COG0504	CTP synthase activity
EIB75_RS15495	COG0706	membrane insertase activity
EIB75_RS15525	COG2354	Protein conserved in bacteria
EIB75_RS15540	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EIB75_RS15550	COG1522	sequence-specific DNA binding
EIB75_RS15565	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
EIB75_RS15570	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EIB75_RS15580	COG2195	Cleaves the N-terminal amino acid of tripeptides
EIB75_RS15590	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EIB75_RS15620	COG1289	transmembrane transporter activity
EIB75_RS15640	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EIB75_RS15645	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EIB75_RS15660	COG0720	synthase
EIB75_RS15670	COG3876	Protein conserved in bacteria
EIB75_RS15690	COG1446	asparaginase
EIB75_RS15695	COG4242	Belongs to the peptidase S51 family
EIB75_RS15700	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EIB75_RS15700	COG0189	ligase activity
EIB75_RS15710	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EIB75_RS15715	COG0745	RESPONSE REGULATOR receiver
EIB75_RS15760	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EIB75_RS15765	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EIB75_RS15775	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EIB75_RS15780	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EIB75_RS15790	COG0165	Argininosuccinate lyase
EIB75_RS15795	COG1522	sequence-specific DNA binding
EIB75_RS15810	COG0505	Belongs to the CarA family
EIB75_RS15835	COG3842	ATPase activity
EIB75_RS15845	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EIB75_RS15845	COG2169	Transcriptional regulator
EIB75_RS15895	COG0531	amino acid
EIB75_RS15905	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EIB75_RS15930	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
EIB75_RS15960	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EIB75_RS16145	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EIB75_RS16160	COG1943	Transposase