locus-tag	class	description
GTU81_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GTU81_RS00010	COG0592	DNA-directed DNA polymerase activity
GTU81_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GTU81_RS00020	COG0187	DNA topoisomerase II activity
GTU81_RS00025	COG0561	phosphatase activity
GTU81_RS00030	COG0823	Involved in the tonB-independent uptake of proteins
GTU81_RS00035	COG5645	(Lipo)protein
GTU81_RS00045	COG3977	Valine--pyruvate aminotransferase
GTU81_RS00060	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GTU81_RS00065	COG2271	Major facilitator Superfamily
GTU81_RS00070	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GTU81_RS00090	COG1609	Transcriptional regulator
GTU81_RS00095	COG2885	chlorophyll binding
GTU81_RS00100	COG2818	Glycosylase
GTU81_RS00105	COG0625	glutathione transferase activity
GTU81_RS00110	COG3058	Necessary for formate dehydrogenase activity
GTU81_RS00120	COG1349	DNA-binding transcription factor activity
GTU81_RS00125	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GTU81_RS00130	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GTU81_RS00135	COG1129	ABC transporter
GTU81_RS00140	COG1172	Belongs to the binding-protein-dependent transport system permease family
GTU81_RS00150	COG0745	RESPONSE REGULATOR receiver
GTU81_RS00170	COG3722	fumarate hydratase activity
GTU81_RS00175	COG0246	Mannitol dehydrogenase
GTU81_RS00180	COG2213	PTS system mannitol-specific
GTU81_RS00180	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GTU81_RS00190	COG2944	sequence-specific DNA binding
GTU81_RS00195	COG1064	alcohol dehydrogenase
GTU81_RS00200	COG0751	glycine-tRNA ligase activity
GTU81_RS00205	COG0752	glycyl-tRNA synthetase alpha subunit
GTU81_RS00210	COG3274	enterobacterial common antigen metabolic process
GTU81_RS00220	COG0246	Mannitol dehydrogenase
GTU81_RS00260	COG1846	Transcriptional regulator
GTU81_RS00265	COG1764	response to oxidative stress
GTU81_RS00280	COG0747	negative chemotaxis
GTU81_RS00285	COG0601	transmembrane transport
GTU81_RS00290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GTU81_RS00295	COG0444	Belongs to the ABC transporter superfamily
GTU81_RS00300	COG4608	Belongs to the ABC transporter superfamily
GTU81_RS00310	COG2894	cell division
GTU81_RS00315	COG1215	transferase activity, transferring glycosyl groups
GTU81_RS00320	COG1215	transferase activity, transferring glycosyl groups
GTU81_RS00325	COG0457	Tetratricopeptide repeat
GTU81_RS00335	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GTU81_RS00345	COG2199	diguanylate cyclase activity
GTU81_RS00345	COG2200	EAL domain
GTU81_RS00350	COG1301	dicarboxylic acid transport
GTU81_RS00365	COG2200	EAL domain
GTU81_RS00370	COG2982	Protein involved in outer membrane biogenesis
GTU81_RS00375	COG0477	Major facilitator Superfamily
GTU81_RS00400	COG1971	Probably functions as a manganese efflux pump
GTU81_RS00405	COG0673	inositol 2-dehydrogenase activity
GTU81_RS00420	COG0673	inositol 2-dehydrogenase activity
GTU81_RS00470	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GTU81_RS00475	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
GTU81_RS00480	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
GTU81_RS00485	COG2205	protein histidine kinase activity
GTU81_RS00495	COG3386	PFAM SMP-30 Gluconolaconase
GTU81_RS00500	COG0840	transmembrane signaling receptor activity
GTU81_RS00505	COG1132	(ABC) transporter
GTU81_RS00530	COG2207	Transcriptional regulator
GTU81_RS00530	COG3708	Transcriptional regulator
GTU81_RS00555	COG2862	Uncharacterized protein family, UPF0114
GTU81_RS00580	COG3038	cytochrome b561
GTU81_RS00590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GTU81_RS00595	COG1234	tRNA 3'-trailer cleavage
GTU81_RS00600	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GTU81_RS00625	COG0742	ribosomal rna small subunit methyltransferase
GTU81_RS00630	COG0589	response to stress
GTU81_RS00640	COG0306	phosphate transporter
GTU81_RS00645	COG2081	HI0933 family
GTU81_RS00680	COG1064	alcohol dehydrogenase
GTU81_RS00690	COG2200	EAL domain
GTU81_RS00695	COG0628	permease
GTU81_RS00705	COG3718	enzyme involved in inositol metabolism
GTU81_RS00715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GTU81_RS00720	COG3962	Belongs to the TPP enzyme family
GTU81_RS00725	COG0673	inositol 2-dehydrogenase activity
GTU81_RS00730	COG1082	Xylose isomerase domain protein TIM barrel
GTU81_RS00740	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GTU81_RS00745	COG0425	Belongs to the sulfur carrier protein TusA family
GTU81_RS00755	COG3714	YhhN family
GTU81_RS00760	COG3776	membrane
GTU81_RS00765	COG0742	ribosomal rna small subunit methyltransferase
GTU81_RS00770	COG0552	protein localization to endoplasmic reticulum
GTU81_RS00775	COG2884	Cell division ATP-binding protein ftsE
GTU81_RS00780	COG2177	Part of the ABC transporter FtsEX involved in
GTU81_RS00790	COG0456	acetyltransferase
GTU81_RS00805	COG4177	L-phenylalanine transmembrane transporter activity
GTU81_RS00810	COG0411	ABC transporter
GTU81_RS00820	COG1653	transport
GTU81_RS00830	COG0395	ABC-type sugar transport system, permease component
GTU81_RS00840	COG0584	glycerophosphoryl diester phosphodiesterase
GTU81_RS00850	COG0405	Gamma-glutamyltransferase
GTU81_RS00855	COG1247	-acetyltransferase
GTU81_RS00860	COG1741	Belongs to the pirin family
GTU81_RS00865	COG1609	Transcriptional regulator
GTU81_RS00870	COG3265	gluconokinase activity
GTU81_RS00875	COG2610	gluconate transmembrane transporter activity
GTU81_RS00890	COG1523	belongs to the glycosyl hydrolase 13 family
GTU81_RS00900	COG0297	glycogen (starch) synthase activity
GTU81_RS00905	COG0058	SHG alpha-glucan phosphorylase activity
GTU81_RS00920	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GTU81_RS00925	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GTU81_RS00930	COG0705	Rhomboid family
GTU81_RS00935	COG1349	DNA-binding transcription factor activity
GTU81_RS00940	COG0058	SHG alpha-glucan phosphorylase activity
GTU81_RS00945	COG1640	4-alpha-glucanotransferase
GTU81_RS00950	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GTU81_RS00950	COG0316	Belongs to the HesB IscA family
GTU81_RS00955	COG1040	competence protein
GTU81_RS00965	COG0366	Alpha amylase catalytic
GTU81_RS00970	COG2183	response to ionizing radiation
GTU81_RS00975	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GTU81_RS00990	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GTU81_RS00995	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GTU81_RS01000	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GTU81_RS01010	COG0494	nUDIX hydrolase
GTU81_RS01015	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GTU81_RS01040	COG4796	Type ii and iii secretion system protein
GTU81_RS01045	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GTU81_RS01050	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GTU81_RS01055	COG3266	domain, Protein
GTU81_RS01065	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GTU81_RS01090	COG0402	S-adenosylhomocysteine deaminase activity
GTU81_RS01095	COG0402	S-adenosylhomocysteine deaminase activity
GTU81_RS01100	COG0738	Major facilitator superfamily
GTU81_RS01115	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GTU81_RS01120	COG1289	transmembrane transporter activity
GTU81_RS01130	COG1765	OsmC-like protein
GTU81_RS01135	COG3954	Phosphoribulokinase
GTU81_RS01140	COG3089	Belongs to the UPF0270 family
GTU81_RS01145	COG0429	hydrolase of the alpha beta-hydrolase fold
GTU81_RS01155	COG4521	taurine ABC transporter
GTU81_RS01165	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GTU81_RS01170	COG2175	clavaminate synthase activity
GTU81_RS01180	COG0488	(ABC) transporter
GTU81_RS01185	COG2249	NAD(P)H dehydrogenase (quinone) activity
GTU81_RS01190	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GTU81_RS01190	COG0475	glutathione-regulated potassium exporter activity
GTU81_RS01195	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
GTU81_RS01200	COG1047	Peptidyl-prolyl cis-trans
GTU81_RS01205	COG2900	Belongs to the SlyX family
GTU81_RS01210	COG0545	Peptidyl-prolyl cis-trans isomerase
GTU81_RS01215	COG2964	Protein conserved in bacteria
GTU81_RS01220	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GTU81_RS01225	COG2923	Belongs to the DsrF TusC family
GTU81_RS01230	COG2168	tRNA wobble position uridine thiolation
GTU81_RS01235	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GTU81_RS01240	COG0049	tRNA binding
GTU81_RS01245	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GTU81_RS01255	COG0051	transcription antitermination factor activity, RNA binding
GTU81_RS01260	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GTU81_RS01265	COG0088	Forms part of the polypeptide exit tunnel
GTU81_RS01270	COG0089	rRNA binding
GTU81_RS01275	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GTU81_RS01280	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GTU81_RS01285	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GTU81_RS01295	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GTU81_RS01300	COG0255	Belongs to the universal ribosomal protein uL29 family
GTU81_RS01305	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GTU81_RS01310	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GTU81_RS01315	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GTU81_RS01320	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GTU81_RS01325	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GTU81_RS01330	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GTU81_RS01335	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GTU81_RS01340	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GTU81_RS01350	COG1841	ribosomal large subunit assembly
GTU81_RS01355	COG0200	Binds to the 23S rRNA
GTU81_RS01360	COG0201	protein transport
GTU81_RS01365	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GTU81_RS01370	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GTU81_RS01375	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GTU81_RS01380	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GTU81_RS01385	COG0202	RNA polymerase activity
GTU81_RS01390	COG0203	ribosomal protein L17
GTU81_RS01400	COG0789	Transcriptional regulator
GTU81_RS01405	COG3036	rescue of stalled ribosome
GTU81_RS01415	COG1970	mechanosensitive ion channel activity
GTU81_RS01425	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GTU81_RS01425	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GTU81_RS01430	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GTU81_RS01435	COG0242	peptide deformylase activity
GTU81_RS01440	COG0758	DNA mediated transformation
GTU81_RS01445	COG2922	Belongs to the Smg family
GTU81_RS01450	COG0551	DNA topoisomerase type I activity
GTU81_RS01460	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GTU81_RS01470	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GTU81_RS01505	COG1126	abc transporter atp-binding protein
GTU81_RS01510	COG0765	amino acid transport
GTU81_RS01515	COG4597	amino acid ABC transporter
GTU81_RS01520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GTU81_RS01525	COG1560	Kdo2-lipid A biosynthetic process
GTU81_RS01545	COG2264	protein methyltransferase activity
GTU81_RS01550	COG4145	pantothenate transmembrane transporter activity
GTU81_RS01555	COG3924	membrane
GTU81_RS01560	COG0439	Biotin carboxylase
GTU81_RS01565	COG0511	ligase activity, forming carbon-carbon bonds
GTU81_RS01570	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GTU81_RS01580	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GTU81_RS01585	COG0604	alcohol dehydrogenase
GTU81_RS01590	COG2199	diguanylate cyclase activity
GTU81_RS01590	COG2200	EAL domain
GTU81_RS01595	COG1077	Cell shape determining protein MreB Mrl
GTU81_RS01600	COG1792	Involved in formation and maintenance of cell shape
GTU81_RS01605	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GTU81_RS01615	COG1530	ribonuclease E activity
GTU81_RS01620	COG3164	Protein of unknown function
GTU81_RS01625	COG0312	modulator of DNA gyrase
GTU81_RS01630	COG0583	DNA-binding transcription factor activity
GTU81_RS01640	COG1566	PFAM secretion protein HlyD family protein
GTU81_RS01645	COG1289	transmembrane transporter activity
GTU81_RS01660	COG1438	arginine binding
GTU81_RS01665	COG0039	L-malate dehydrogenase activity
GTU81_RS01670	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GTU81_RS01675	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GTU81_RS01680	COG3105	Protein conserved in bacteria
GTU81_RS01685	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GTU81_RS01690	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GTU81_RS01695	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GTU81_RS01700	COG0625	glutathione transferase activity
GTU81_RS01705	COG2969	positive regulation of protein catabolic process
GTU81_RS01710	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GTU81_RS01715	COG0069	glutamate synthase activity
GTU81_RS01715	COG0067	glutamate synthase
GTU81_RS01715	COG0070	glutamate synthase
GTU81_RS01720	COG0784	Response regulator, receiver
GTU81_RS01720	COG5002	protein histidine kinase activity
GTU81_RS01720	COG2198	Histidine kinase
GTU81_RS01730	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GTU81_RS01735	COG1660	Displays ATPase and GTPase activities
GTU81_RS01750	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GTU81_RS01755	COG1137	ATPase activity
GTU81_RS01760	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GTU81_RS01765	COG3117	lipopolysaccharide transmembrane transporter activity
GTU81_RS01770	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GTU81_RS01780	COG0530	calcium, potassium:sodium antiporter activity
GTU81_RS01785	COG1127	ABC transporter
GTU81_RS01790	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GTU81_RS01795	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GTU81_RS01800	COG2854	intermembrane phospholipid transfer
GTU81_RS01805	COG3113	response to antibiotic
GTU81_RS01815	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GTU81_RS01820	COG3423	Transcriptional regulator
GTU81_RS01825	COG0142	geranyltranstransferase activity
GTU81_RS01830	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GTU81_RS01835	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GTU81_RS01845	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GTU81_RS01850	COG0642	Histidine kinase
GTU81_RS01855	COG0745	RESPONSE REGULATOR receiver
GTU81_RS01860	COG2027	D-alanyl-D-alanine carboxypeptidase
GTU81_RS01870	COG1534	Rna-binding protein
GTU81_RS01875	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GTU81_RS01885	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GTU81_RS01890	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GTU81_RS01895	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GTU81_RS01910	COG0779	Required for maturation of 30S ribosomal subunits
GTU81_RS01915	COG0195	Participates in both transcription termination and antitermination
GTU81_RS01925	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GTU81_RS01930	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GTU81_RS01935	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GTU81_RS01940	COG1185	polyribonucleotide nucleotidyltransferase activity
GTU81_RS01955	COG0513	Belongs to the DEAD box helicase family
GTU81_RS01960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GTU81_RS01965	COG3153	acetyltransferase
GTU81_RS01970	COG2827	Endonuclease containing a URI domain
GTU81_RS01975	COG3766	membrane
GTU81_RS01980	COG0602	queuosine metabolic process
GTU81_RS01990	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GTU81_RS01995	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GTU81_RS02005	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
GTU81_RS02015	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GTU81_RS02020	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
GTU81_RS02025	COG0456	acetyltransferase
GTU81_RS02040	COG2271	Major facilitator Superfamily
GTU81_RS02050	COG0525	valine-tRNA ligase activity
GTU81_RS02055	COG2927	DNA polymerase III (CHI subunit)
GTU81_RS02060	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GTU81_RS02065	COG0795	lipopolysaccharide-transporting ATPase activity
GTU81_RS02070	COG0795	lipopolysaccharide-transporting ATPase activity
GTU81_RS02075	COG2733	membrane
GTU81_RS02080	COG0433	COG0433 Predicted ATPase
GTU81_RS02095	COG0582	viral genome integration into host DNA
GTU81_RS02115	COG1715	Restriction endonuclease
GTU81_RS02165	COG2003	Belongs to the UPF0758 family
GTU81_RS02205	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GTU81_RS02210	COG3012	SEC-C Motif Domain Protein
GTU81_RS02210	COG3318	Belongs to the UPF0149 family
GTU81_RS02215	COG1464	Belongs to the NlpA lipoprotein family
GTU81_RS02225	COG3423	Transcriptional regulator
GTU81_RS02230	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GTU81_RS02245	COG3663	DNA glycosylase
GTU81_RS02255	COG0358	DNA primase activity
GTU81_RS02260	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GTU81_RS02265	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GTU81_RS02270	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GTU81_RS02275	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GTU81_RS02280	COG1968	undecaprenyl-diphosphatase activity
GTU81_RS02285	COG0617	tRNA 3'-terminal CCA addition
GTU81_RS02290	COG4991	sh3 domain protein
GTU81_RS02295	COG3025	triphosphatase activity
GTU81_RS02305	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GTU81_RS02305	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GTU81_RS02315	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GTU81_RS02320	COG3384	dioxygenase
GTU81_RS02325	COG0754	glutathionylspermidine amidase activity
GTU81_RS02330	COG5463	Belongs to the UPF0441 family
GTU81_RS02335	COG1538	Outer membrane efflux protein
GTU81_RS02340	COG0494	nUDIX hydrolase
GTU81_RS02345	COG3151	Protein conserved in bacteria
GTU81_RS02350	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GTU81_RS02355	COG3150	esterase
GTU81_RS02380	COG0167	dihydroorotate dehydrogenase activity
GTU81_RS02395	COG0300	oxidoreductase activity
GTU81_RS02395	COG3321	synthase
GTU81_RS02395	COG1028	Short-chain dehydrogenase reductase Sdr
GTU81_RS02395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GTU81_RS02395	COG0318	PFAM AMP-dependent synthetase and ligase
GTU81_RS02455	COG2132	Multicopper oxidase
GTU81_RS02460	COG0656	L-ascorbic acid biosynthetic process
GTU81_RS02465	COG2207	Transcriptional regulator
GTU81_RS02470	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GTU81_RS02475	COG0076	glutamate decarboxylase activity
GTU81_RS02480	COG0586	Pfam SNARE associated Golgi protein
GTU81_RS02485	COG0626	cystathionine gamma-synthase activity
GTU81_RS02495	COG0848	biopolymer transport protein
GTU81_RS02505	COG1028	Short-chain dehydrogenase reductase Sdr
GTU81_RS02535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GTU81_RS02560	COG0671	phosphoesterase, PA-phosphatase related
GTU81_RS02570	COG1528	Iron-storage protein
GTU81_RS02580	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GTU81_RS02595	COG2723	6-phospho-beta-galactosidase activity
GTU81_RS02600	COG2723	6-phospho-beta-galactosidase activity
GTU81_RS02605	COG1447	Phosphotransferase system cellobiose-specific component IIA
GTU81_RS02610	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GTU81_RS02620	COG1609	Transcriptional regulator
GTU81_RS02645	COG1522	sequence-specific DNA binding
GTU81_RS02665	COG3275	phosphorelay sensor kinase activity
GTU81_RS02675	COG2879	small protein
GTU81_RS02680	COG1966	Carbon starvation protein
GTU81_RS02715	COG0151	Belongs to the GarS family
GTU81_RS02720	COG0151	Belongs to the GarS family
GTU81_RS02735	COG4792	protein secretion
GTU81_RS02745	COG4794	Type iii secretion
GTU81_RS02770	COG1157	protein secretion by the type III secretion system
GTU81_RS02800	COG2197	response regulator
GTU81_RS02890	COG5297	Belongs to the glycosyl hydrolase family 6
GTU81_RS02905	COG0583	DNA-binding transcription factor activity
GTU81_RS02925	COG3179	chitinase
GTU81_RS02990	COG1982	Orn Lys Arg decarboxylase major
GTU81_RS03000	COG0741	lytic transglycosylase activity
GTU81_RS03005	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
GTU81_RS03020	COG3171	Protein conserved in bacteria
GTU81_RS03030	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GTU81_RS03035	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GTU81_RS03040	COG0762	integral membrane protein
GTU81_RS03045	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GTU81_RS03050	COG2805	Type II/IV secretion system protein
GTU81_RS03065	COG4232	protein-disulfide reductase activity
GTU81_RS03075	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GTU81_RS03080	COG1678	Uncharacterized ACR, COG1678
GTU81_RS03090	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GTU81_RS03095	COG2356	endonuclease I
GTU81_RS03100	COG3091	SprT-like family
GTU81_RS03105	COG2814	Major facilitator Superfamily
GTU81_RS03110	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GTU81_RS03115	COG1166	arginine decarboxylase activity
GTU81_RS03155	COG0501	Belongs to the peptidase M48B family
GTU81_RS03160	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GTU81_RS03165	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GTU81_RS03170	COG0126	phosphoglycerate kinase activity
GTU81_RS03175	COG0191	fructose-bisphosphate aldolase activity
GTU81_RS03180	COG0668	transmembrane transport
GTU81_RS03195	COG2072	flavoprotein involved in K transport
GTU81_RS03210	COG0673	inositol 2-dehydrogenase activity
GTU81_RS03220	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GTU81_RS03230	COG0583	DNA-binding transcription factor activity
GTU81_RS03235	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GTU81_RS03245	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GTU81_RS03250	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GTU81_RS03260	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GTU81_RS03265	COG3079	Belongs to the UPF0149 family
GTU81_RS03270	COG0006	proline dipeptidase activity
GTU81_RS03275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GTU81_RS03280	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GTU81_RS03285	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GTU81_RS03290	COG0509	glycine decarboxylation via glycine cleavage system
GTU81_RS03300	COG1028	Short-chain dehydrogenase reductase Sdr
GTU81_RS03310	COG1272	protein, Hemolysin III
GTU81_RS03315	COG0354	folic acid binding
GTU81_RS03320	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GTU81_RS03330	COG0716	FMN binding
GTU81_RS03335	COG0697	spore germination
GTU81_RS03345	COG4974	Belongs to the 'phage' integrase family
GTU81_RS03355	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GTU81_RS03365	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GTU81_RS03375	COG2814	Major facilitator Superfamily
GTU81_RS03380	COG0583	DNA-binding transcription factor activity
GTU81_RS03390	COG1609	Transcriptional regulator
GTU81_RS03405	COG3210	domain, Protein
GTU81_RS03420	COG3210	domain, Protein
GTU81_RS03435	COG3210	domain, Protein
GTU81_RS03450	COG3210	domain, Protein
GTU81_RS03470	COG2831	hemolysin activation secretion protein
GTU81_RS03475	COG0768	penicillin binding
GTU81_RS03485	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GTU81_RS03510	COG0204	Acyl-transferase
GTU81_RS03510	COG0318	PFAM AMP-dependent synthetase and ligase
GTU81_RS03520	COG0667	Aldo Keto reductase
GTU81_RS03530	COG0861	Integral membrane protein TerC family
GTU81_RS03535	COG3066	DNA modification
GTU81_RS03540	COG1051	belongs to the nudix hydrolase family
GTU81_RS03550	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GTU81_RS03555	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GTU81_RS03560	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
GTU81_RS03570	COG4795	General secretion pathway protein
GTU81_RS03585	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GTU81_RS03595	COG1074	ATP-dependent DNA helicase activity
GTU81_RS03600	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GTU81_RS03610	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GTU81_RS03610	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GTU81_RS03615	COG0860	N-Acetylmuramoyl-L-alanine amidase
GTU81_RS03635	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GTU81_RS03640	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GTU81_RS03645	COG2166	iron-sulfur cluster assembly
GTU81_RS03650	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GTU81_RS03660	COG0583	DNA-binding transcription factor activity
GTU81_RS03665	COG2363	Small membrane protein
GTU81_RS03670	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
GTU81_RS03675	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GTU81_RS03680	COG1611	Belongs to the LOG family
GTU81_RS03685	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GTU81_RS03685	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GTU81_RS03695	COG3098	single-species biofilm formation
GTU81_RS03700	COG0564	pseudouridine synthase activity
GTU81_RS03705	COG0716	FMN binding
GTU81_RS03710	COG1929	Belongs to the glycerate kinase type-1 family
GTU81_RS03720	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GTU81_RS03725	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GTU81_RS03730	COG3956	TIGRFAM MazG family protein
GTU81_RS03735	COG0504	CTP synthase activity
GTU81_RS03740	COG0148	phosphopyruvate hydratase activity
GTU81_RS03745	COG2755	lipolytic protein G-D-S-L family
GTU81_RS03745	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GTU81_RS03750	COG0602	queuosine metabolic process
GTU81_RS03755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GTU81_RS03760	COG1126	abc transporter atp-binding protein
GTU81_RS03765	COG0765	amino acid transport
GTU81_RS03775	COG0720	synthase
GTU81_RS03785	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GTU81_RS03790	COG0175	sulfate reduction
GTU81_RS03800	COG1648	precorrin-2 dehydrogenase activity
GTU81_RS03800	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GTU81_RS03805	COG0175	sulfate reduction
GTU81_RS03810	COG2895	sulfate adenylyltransferase (ATP) activity
GTU81_RS03815	COG0529	Catalyzes the synthesis of activated sulfate
GTU81_RS03825	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GTU81_RS03830	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GTU81_RS03835	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GTU81_RS03840	COG0585	pseudouridine synthase activity
GTU81_RS03845	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GTU81_RS03850	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GTU81_RS03855	COG1388	LysM domain
GTU81_RS03855	COG4942	peptidase
GTU81_RS03860	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GTU81_RS03865	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GTU81_RS04005	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GTU81_RS04025	COG5455	response to cobalt ion
GTU81_RS04030	COG2951	lytic endotransglycosylase activity
GTU81_RS04035	COG1546	Belongs to the CinA family
GTU81_RS04040	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GTU81_RS04055	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GTU81_RS04080	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GTU81_RS04085	COG1238	metal cluster binding
GTU81_RS04090	COG2918	glutathione biosynthetic process
GTU81_RS04100	COG4536	flavin adenine dinucleotide binding
GTU81_RS04105	COG4137	Cytochrome C assembly protein
GTU81_RS04110	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GTU81_RS04115	COG0228	four-way junction DNA binding
GTU81_RS04130	COG0335	large ribosomal subunit rRNA binding
GTU81_RS04155	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GTU81_RS04160	COG1605	Chorismate mutase
GTU81_RS04160	COG0287	Prephenate dehydrogenase
GTU81_RS04165	COG0077	Prephenate dehydratase
GTU81_RS04165	COG1605	Chorismate mutase
GTU81_RS04175	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GTU81_RS04180	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GTU81_RS04185	COG0564	pseudouridine synthase activity
GTU81_RS04195	COG0542	response to heat
GTU81_RS04230	COG3021	interspecies interaction between organisms
GTU81_RS04240	COG0741	lytic transglycosylase activity
GTU81_RS04240	COG1388	LysM domain
GTU81_RS04245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GTU81_RS04250	COG2226	methyltransferase
GTU81_RS04255	COG0328	RNA-DNA hybrid ribonuclease activity
GTU81_RS04260	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GTU81_RS04270	COG1953	Uracil, thiamine, allantoin
GTU81_RS04300	COG1715	Restriction endonuclease
GTU81_RS04340	COG0765	amino acid transport
GTU81_RS04345	COG0765	amino acid transport
GTU81_RS04355	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GTU81_RS04370	COG2351	hydroxyisourate hydrolase activity
GTU81_RS04375	COG2233	PERMEase
GTU81_RS04380	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GTU81_RS04385	COG0436	Aminotransferase
GTU81_RS04405	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
GTU81_RS04410	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
GTU81_RS04420	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
GTU81_RS04425	COG1960	acyl-CoA dehydrogenase activity
GTU81_RS04430	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GTU81_RS04435	COG0121	glutamine amidotransferase
GTU81_RS04440	COG3034	peptidoglycan biosynthetic process
GTU81_RS04450	COG2195	Cleaves the N-terminal amino acid of tripeptides
GTU81_RS04455	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
GTU81_RS04460	COG1073	alpha beta
GTU81_RS04475	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GTU81_RS04480	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GTU81_RS04485	COG2832	Protein of unknown function (DUF454)
GTU81_RS04490	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GTU81_RS04545	COG4608	Belongs to the ABC transporter superfamily
GTU81_RS04550	COG0444	Belongs to the ABC transporter superfamily
GTU81_RS04555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GTU81_RS04560	COG0601	transmembrane transport
GTU81_RS04565	COG0747	negative chemotaxis
GTU81_RS04585	COG1278	Cold shock
GTU81_RS04590	COG3250	beta-galactosidase activity
GTU81_RS04605	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GTU81_RS04610	COG1671	Belongs to the UPF0178 family
GTU81_RS04615	COG3416	Protein conserved in bacteria
GTU81_RS04620	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GTU81_RS04645	COG4126	flavin adenine dinucleotide binding
GTU81_RS04650	COG3123	guanosine phosphorylase activity
GTU81_RS04655	COG2974	May be involved in recombination
GTU81_RS04695	COG0419	ATPase involved in DNA repair
GTU81_RS04700	COG0420	3'-5' exonuclease activity
GTU81_RS04710	COG5002	protein histidine kinase activity
GTU81_RS04720	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GTU81_RS04735	COG0450	alkyl hydroperoxide reductase
GTU81_RS04740	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
GTU81_RS04745	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GTU81_RS04760	COG2246	polysaccharide biosynthetic process
GTU81_RS04765	COG0343	queuine tRNA-ribosyltransferase activity
GTU81_RS04770	COG1862	Preprotein translocase
GTU81_RS04775	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GTU81_RS04780	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GTU81_RS04790	COG1652	LysM domain
GTU81_RS04795	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GTU81_RS04800	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GTU81_RS04800	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GTU81_RS04805	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GTU81_RS04810	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GTU81_RS04815	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GTU81_RS04820	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GTU81_RS04825	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GTU81_RS04830	COG0142	geranyltranstransferase activity
GTU81_RS04835	COG1722	exodeoxyribonuclease VII activity
GTU81_RS04840	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GTU81_RS04840	COG0301	tRNA thio-modification
GTU81_RS04850	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GTU81_RS04855	COG1666	GTP binding
GTU81_RS04860	COG2814	Major facilitator Superfamily
GTU81_RS04865	COG0109	protoheme IX farnesyltransferase activity
GTU81_RS04870	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GTU81_RS04875	COG1845	cytochrome c oxidase, subunit III
GTU81_RS04880	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GTU81_RS04885	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GTU81_RS04890	COG2223	nitrite transmembrane transporter activity
GTU81_RS04895	COG3056	Lipoprotein
GTU81_RS04900	COG0271	Belongs to the BolA IbaG family
GTU81_RS04905	COG0544	peptidyl-prolyl cis-trans isomerase activity
GTU81_RS04920	COG0740	serine-type endopeptidase activity
GTU81_RS04935	COG0776	regulation of translation
GTU81_RS04940	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GTU81_RS04945	COG1555	photosystem II stabilization
GTU81_RS04950	COG0824	Thioesterase
GTU81_RS04955	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GTU81_RS04965	COG1522	sequence-specific DNA binding
GTU81_RS04970	COG1132	(ABC) transporter
GTU81_RS04975	COG1132	(ABC) transporter
GTU81_RS04980	COG0347	Belongs to the P(II) protein family
GTU81_RS04985	COG0004	ammonium transporteR
GTU81_RS04990	COG1946	Acyl-CoA thioesterase
GTU81_RS04995	COG3126	Type III secretion system lipoprotein chaperone (YscW)
GTU81_RS05000	COG3695	enzyme binding
GTU81_RS05025	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GTU81_RS05030	COG0254	rRNA binding
GTU81_RS05035	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GTU81_RS05040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GTU81_RS05045	COG1309	transcriptional regulator
GTU81_RS05065	COG2832	Protein of unknown function (DUF454)
GTU81_RS05070	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GTU81_RS05080	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GTU81_RS05085	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GTU81_RS05090	COG0326	Molecular chaperone. Has ATPase activity
GTU81_RS05095	COG0583	DNA-binding transcription factor activity
GTU81_RS05120	COG0563	adenylate kinase activity
GTU81_RS05125	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GTU81_RS05130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GTU81_RS05140	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GTU81_RS05140	COG4651	solute:proton antiporter activity
GTU81_RS05145	COG2223	nitrite transmembrane transporter activity
GTU81_RS05150	COG0737	Belongs to the 5'-nucleotidase family
GTU81_RS05160	COG0583	DNA-binding transcription factor activity
GTU81_RS05165	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GTU81_RS05170	COG3735	TraB family
GTU81_RS05175	COG2217	Heavy metal translocating P-type atpase
GTU81_RS05185	COG1585	Membrane protein implicated in regulation of membrane protease activity
GTU81_RS05190	COG0330	HflC and HflK could
GTU81_RS05195	COG3118	belongs to the thioredoxin family
GTU81_RS05200	COG0300	oxidoreductase activity
GTU81_RS05225	COG2755	lipolytic protein G-D-S-L family
GTU81_RS05230	COG4181	ATPase activity
GTU81_RS05235	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GTU81_RS05240	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GTU81_RS05245	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GTU81_RS05255	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GTU81_RS05260	COG0215	cysteine-tRNA ligase activity
GTU81_RS05265	COG1064	alcohol dehydrogenase
GTU81_RS05270	COG2501	S4 domain
GTU81_RS05275	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GTU81_RS05285	COG0582	viral genome integration into host DNA
GTU81_RS05310	COG1764	response to oxidative stress
GTU81_RS05325	COG0646	methionine synthase
GTU81_RS05325	COG1410	methionine synthase
GTU81_RS05340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GTU81_RS05345	COG4172	Belongs to the ABC transporter superfamily
GTU81_RS05360	COG4772	TonB-dependent receptor
GTU81_RS05365	COG4993	Dehydrogenase
GTU81_RS05375	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GTU81_RS05380	COG0463	Glycosyl transferase, family 2
GTU81_RS05385	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GTU81_RS05385	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GTU81_RS05390	COG0726	polysaccharide deacetylase
GTU81_RS05395	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GTU81_RS05400	COG2076	Multidrug Resistance protein
GTU81_RS05405	COG2076	Multidrug Resistance protein
GTU81_RS05415	COG1294	oxidase, subunit
GTU81_RS05420	COG1271	oxidase subunit
GTU81_RS05435	COG1349	DNA-binding transcription factor activity
GTU81_RS05440	COG2084	Dehydrogenase
GTU81_RS05445	COG3395	kinase activity
GTU81_RS05450	COG0235	Class ii aldolase
GTU81_RS05455	COG3622	Belongs to the hyi family
GTU81_RS05460	COG2610	gluconate transmembrane transporter activity
GTU81_RS05465	COG2610	gluconate transmembrane transporter activity
GTU81_RS05480	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GTU81_RS05485	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GTU81_RS05490	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GTU81_RS05495	COG0321	lipoyl(octanoyl) transferase activity
GTU81_RS05500	COG2921	Belongs to the UPF0250 family
GTU81_RS05505	COG1686	Belongs to the peptidase S11 family
GTU81_RS05510	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GTU81_RS05515	COG0772	Belongs to the SEDS family
GTU81_RS05520	COG0768	penicillin binding
GTU81_RS05525	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GTU81_RS05530	COG0799	negative regulation of ribosome biogenesis
GTU81_RS05540	COG1466	dna polymerase III delta subunit
GTU81_RS05545	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
GTU81_RS05550	COG0495	leucyl-tRNA aminoacylation
GTU81_RS05555	COG2888	peptidyl-tyrosine sulfation
GTU81_RS05560	COG1126	abc transporter atp-binding protein
GTU81_RS05565	COG0765	amino acid transport
GTU81_RS05570	COG0765	amino acid transport
GTU81_RS05580	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GTU81_RS05585	COG4535	Mg2 and Co2 transporter CorC
GTU81_RS05590	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GTU81_RS05595	COG1702	phosphate starvation-inducible protein PhoH
GTU81_RS05600	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GTU81_RS05605	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GTU81_RS05640	COG0367	asparagine synthase
GTU81_RS05645	COG0647	UMP catabolic process
GTU81_RS05650	COG1846	Transcriptional regulator
GTU81_RS05650	COG1940	carbohydrate kinase activity
GTU81_RS05655	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GTU81_RS05660	COG0363	glucosamine-6-phosphate deaminase activity
GTU81_RS05670	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GTU81_RS05675	COG0814	amino acid
GTU81_RS05680	COG0735	belongs to the Fur family
GTU81_RS05695	COG0596	Alpha beta hydrolase
GTU81_RS05700	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
GTU81_RS05705	COG0033	Phosphoglucomutase
GTU81_RS05710	COG0745	RESPONSE REGULATOR receiver
GTU81_RS05720	COG3272	Protein of unknown function (DUF1722)
GTU81_RS05725	COG0415	Belongs to the DNA photolyase family
GTU81_RS05735	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GTU81_RS05740	COG1984	allophanate hydrolase subunit 2
GTU81_RS05745	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GTU81_RS05750	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GTU81_RS05760	COG0372	Belongs to the citrate synthase family
GTU81_RS05765	COG2009	succinate dehydrogenase
GTU81_RS05770	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GTU81_RS05775	COG1053	succinate dehydrogenase
GTU81_RS05780	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GTU81_RS05785	COG0567	Dehydrogenase, E1 component
GTU81_RS05790	COG0508	dehydrogenase complex catalyzes the overall conversion of
GTU81_RS05795	COG0045	succinate-CoA ligase (ADP-forming) activity
GTU81_RS05800	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GTU81_RS05805	COG0824	Thioesterase
GTU81_RS05810	COG0811	peptide transport
GTU81_RS05815	COG0848	biopolymer transport protein
GTU81_RS05820	COG3064	Membrane
GTU81_RS05825	COG0823	Involved in the tonB-independent uptake of proteins
GTU81_RS05830	COG2885	chlorophyll binding
GTU81_RS05835	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GTU81_RS05900	COG1230	cation diffusion facilitator family transporter
GTU81_RS05910	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GTU81_RS05925	COG0588	phosphoglycerate mutase activity
GTU81_RS05930	COG2017	converts alpha-aldose to the beta-anomer
GTU81_RS05935	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GTU81_RS05945	COG1119	ATPase activity
GTU81_RS05950	COG2005	Transcriptional regulator
GTU81_RS05950	COG3585	molybdate ion transport
GTU81_RS05960	COG0725	ABC transporter, periplasmic molybdate-binding protein
GTU81_RS05965	COG4149	molybdate abc transporter
GTU81_RS05975	COG0561	phosphatase activity
GTU81_RS05980	COG2706	6-phosphogluconolactonase activity
GTU81_RS05985	COG1881	PFAM PEBP family protein
GTU81_RS05990	COG2130	NADP-dependent
GTU81_RS06000	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GTU81_RS06005	COG0156	8-amino-7-oxononanoate synthase activity
GTU81_RS06015	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GTU81_RS06025	COG0556	nucleotide-excision repair
GTU81_RS06040	COG0521	Mo-molybdopterin cofactor biosynthetic process
GTU81_RS06045	COG0315	cyclic pyranopterin monophosphate synthase activity
GTU81_RS06050	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GTU81_RS06065	COG0670	Belongs to the BI1 family
GTU81_RS06080	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GTU81_RS06085	COG1376	ErfK ybiS ycfS ynhG family protein
GTU81_RS06090	COG3387	PFAM Glycoside hydrolase 15-related
GTU81_RS06095	COG0586	Pfam SNARE associated Golgi protein
GTU81_RS06105	COG1686	Belongs to the peptidase S11 family
GTU81_RS06110	COG1511	domain protein
GTU81_RS06110	COG3264	Mechanosensitive ion channel
GTU81_RS06120	COG0277	FAD linked oxidase domain protein
GTU81_RS06135	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GTU81_RS06155	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GTU81_RS06170	COG4221	oxidoreductase activity
GTU81_RS06180	COG0789	Transcriptional regulator
GTU81_RS06200	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GTU81_RS06205	COG1473	amidohydrolase
GTU81_RS06210	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GTU81_RS06215	COG2986	histidine ammonia-lyase
GTU81_RS06230	COG0402	S-adenosylhomocysteine deaminase activity
GTU81_RS06235	COG1228	amidohydrolase
GTU81_RS06245	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
GTU81_RS06250	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GTU81_RS06265	COG0641	radical SAM
GTU81_RS06275	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
GTU81_RS06280	COG0668	transmembrane transport
GTU81_RS06290	COG1126	abc transporter atp-binding protein
GTU81_RS06295	COG0765	amino acid transport
GTU81_RS06300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GTU81_RS06305	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GTU81_RS06310	COG0783	Belongs to the Dps family
GTU81_RS06320	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GTU81_RS06325	COG1321	iron dependent repressor
GTU81_RS06330	COG1566	PFAM secretion protein HlyD family protein
GTU81_RS06335	COG2814	Major facilitator Superfamily
GTU81_RS06350	COG2814	Major facilitator Superfamily
GTU81_RS06355	COG0488	(ABC) transporter
GTU81_RS06365	COG0303	'Molybdopterin
GTU81_RS06375	COG4172	Belongs to the ABC transporter superfamily
GTU81_RS06395	COG1686	Belongs to the peptidase S11 family
GTU81_RS06400	COG0814	amino acid
GTU81_RS06435	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GTU81_RS06440	COG3842	ATPase activity
GTU81_RS06445	COG1176	ABC-type spermidine putrescine transport system, permease component I
GTU81_RS06450	COG1177	transmembrane transport
GTU81_RS06460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GTU81_RS06465	COG4160	amino acid transport
GTU81_RS06470	COG4215	(ABC) transporter
GTU81_RS06475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GTU81_RS06480	COG1126	abc transporter atp-binding protein
GTU81_RS06490	COG0393	Putative heavy-metal-binding
GTU81_RS06495	COG3023	N-Acetylmuramoyl-L-alanine amidase
GTU81_RS06500	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
GTU81_RS06505	COG0028	Belongs to the TPP enzyme family
GTU81_RS06510	COG3593	DNA synthesis involved in DNA repair
GTU81_RS06515	COG1278	Cold shock
GTU81_RS06525	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GTU81_RS06530	COG0542	response to heat
GTU81_RS06535	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GTU81_RS06540	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GTU81_RS06545	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GTU81_RS06550	COG4988	ABC transporter
GTU81_RS06555	COG0492	ferredoxin-NADP+ reductase activity
GTU81_RS06565	COG1674	ftsk spoiiie
GTU81_RS06565	COG3107	peptidoglycan biosynthetic process
GTU81_RS06570	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GTU81_RS06575	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GTU81_RS06580	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GTU81_RS06585	COG0477	Major facilitator Superfamily
GTU81_RS06595	COG1944	ATP diphosphatase activity
GTU81_RS06600	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GTU81_RS06605	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GTU81_RS06610	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GTU81_RS06615	COG0539	negative regulation of cytoplasmic translation
GTU81_RS06620	COG0776	regulation of translation
GTU81_RS06625	COG0658	competence protein
GTU81_RS06625	COG2333	competence protein COMEC
GTU81_RS06635	COG1663	tetraacyldisaccharide 4'-kinase activity
GTU81_RS06640	COG2835	tetraacyldisaccharide 4'-kinase activity
GTU81_RS06645	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GTU81_RS06650	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GTU81_RS06655	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GTU81_RS06660	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
GTU81_RS06665	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
GTU81_RS06670	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GTU81_RS06675	COG2989	Protein conserved in bacteria
GTU81_RS06680	COG3108	Peptidase M15
GTU81_RS06685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GTU81_RS06690	COG1448	Aminotransferase
GTU81_RS06700	COG0017	Asparaginyl-tRNA synthetase
GTU81_RS06705	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GTU81_RS06710	COG0308	aminopeptidase N
GTU81_RS06720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GTU81_RS06730	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GTU81_RS06735	COG0431	NADPH-dependent FMN reductase
GTU81_RS06740	COG0167	dihydroorotate dehydrogenase activity
GTU81_RS06750	COG3217	Mosc domain protein beta barrel domain protein
GTU81_RS06750	COG0633	Ferredoxin
GTU81_RS06755	COG0116	Belongs to the methyltransferase superfamily
GTU81_RS06755	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GTU81_RS06760	COG0488	(ABC) transporter
GTU81_RS06765	COG2995	paraquat-inducible protein a
GTU81_RS06770	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GTU81_RS06770	COG3008	intermembrane lipid transfer
GTU81_RS06775	COG3009	Protein conserved in bacteria
GTU81_RS06780	COG3130	regulation of translation
GTU81_RS06785	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GTU81_RS06790	COG1067	ATP-dependent peptidase activity
GTU81_RS06795	COG3120	sequence-specific DNA binding
GTU81_RS06800	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GTU81_RS06800	COG2885	chlorophyll binding
GTU81_RS06810	COG3070	regulator of competence-specific genes
GTU81_RS06815	COG1289	transmembrane transporter activity
GTU81_RS06820	COG3304	Inner membrane component domain
GTU81_RS06825	COG0210	DNA helicase
GTU81_RS06830	COG1803	Methylglyoxal synthase
GTU81_RS06840	COG3785	DNA binding
GTU81_RS06845	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GTU81_RS06855	COG2920	part of a sulfur-relay system
GTU81_RS06860	COG0670	Belongs to the BI1 family
GTU81_RS06880	COG1012	belongs to the aldehyde dehydrogenase family
GTU81_RS06895	COG1309	transcriptional regulator
GTU81_RS06905	COG1113	amino acid transport
GTU81_RS06910	COG2197	response regulator
GTU81_RS06920	COG3136	membrane protein required for alginate biosynthesis
GTU81_RS06930	COG2197	response regulator
GTU81_RS06935	COG0322	excinuclease ABC activity
GTU81_RS06940	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GTU81_RS06965	COG1846	Transcriptional regulator
GTU81_RS06995	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GTU81_RS07015	COG5645	(Lipo)protein
GTU81_RS07025	COG1560	Kdo2-lipid A biosynthetic process
GTU81_RS07030	COG1054	Belongs to the UPF0176 family
GTU81_RS07040	COG3038	cytochrome b561
GTU81_RS07060	COG0418	dihydroorotase activity
GTU81_RS07070	COG2999	glutathione oxidoreductase activity
GTU81_RS07075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GTU81_RS07090	COG3418	PFAM FlgN family protein
GTU81_RS07105	COG1815	bacterial-type flagellum-dependent cell motility
GTU81_RS07110	COG1558	bacterial-type flagellum-dependent cell motility
GTU81_RS07115	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GTU81_RS07120	COG1749	Flagellar hook protein flgE
GTU81_RS07150	COG1256	bacterial-type flagellum assembly
GTU81_RS07155	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GTU81_RS07160	COG1530	ribonuclease E activity
GTU81_RS07160	COG1530	ribonuclease E activity
GTU81_RS07165	COG0564	pseudouridine synthase activity
GTU81_RS07170	COG0424	maF-like protein
GTU81_RS07175	COG1399	metal-binding, possibly nucleic acid-binding protein
GTU81_RS07180	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GTU81_RS07185	COG0416	fatty acid biosynthetic process
GTU81_RS07190	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GTU81_RS07195	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GTU81_RS07205	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GTU81_RS07210	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GTU81_RS07215	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GTU81_RS07220	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GTU81_RS07225	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GTU81_RS07230	COG0470	DNA polymerase III
GTU81_RS07235	COG0084	hydrolase, TatD family'
GTU81_RS07240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GTU81_RS07240	COG1263	PTS System
GTU81_RS07245	COG0537	adenosine 5'-monophosphoramidase activity
GTU81_RS07255	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
GTU81_RS07265	COG1472	Belongs to the glycosyl hydrolase 3 family
GTU81_RS07275	COG1252	NADH dehydrogenase
GTU81_RS07280	COG3134	Outer membrane lipoprotein
GTU81_RS07285	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GTU81_RS07290	COG1215	transferase activity, transferring glycosyl groups
GTU81_RS07340	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GTU81_RS07345	COG1580	Controls the rotational direction of flagella during chemotaxis
GTU81_RS07365	COG1317	bacterial-type flagellum organization
GTU81_RS07370	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GTU81_RS07380	COG1677	Flagellar hook-basal body complex protein FliE
GTU81_RS07385	COG0835	chemotaxis
GTU81_RS07385	COG0784	Response regulator, receiver
GTU81_RS07405	COG2199	diguanylate cyclase activity
GTU81_RS07410	COG4591	ABC-type transport system involved in lipoprotein release permease component
GTU81_RS07420	COG4591	ABC-type transport system involved in lipoprotein release permease component
GTU81_RS07425	COG1940	carbohydrate kinase activity
GTU81_RS07435	COG3135	benzoate transporter
GTU81_RS07440	COG1396	sequence-specific DNA binding
GTU81_RS07445	COG2850	peptidyl-arginine hydroxylation
GTU81_RS07455	COG0745	RESPONSE REGULATOR receiver
GTU81_RS07460	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GTU81_RS07465	COG2915	High frequency lysogenization protein hflD homolog
GTU81_RS07485	COG0538	isocitrate dehydrogenase activity
GTU81_RS07530	COG1619	proteins homologs of microcin C7 resistance protein MccF
GTU81_RS07540	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
GTU81_RS07545	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
GTU81_RS07550	COG2261	transglycosylase associated protein
GTU81_RS07560	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GTU81_RS07575	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GTU81_RS07575	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GTU81_RS07595	COG4565	transcriptional regulatory protein
GTU81_RS07600	COG3290	protein histidine kinase activity
GTU81_RS07750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GTU81_RS07760	COG0012	GTP binding
GTU81_RS07765	COG0659	secondary active sulfate transmembrane transporter activity
GTU81_RS07775	COG0193	aminoacyl-tRNA hydrolase activity
GTU81_RS07790	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GTU81_RS07795	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
GTU81_RS07800	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GTU81_RS07805	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GTU81_RS07810	COG2890	protein-(glutamine-N5) methyltransferase activity
GTU81_RS07820	COG2912	Transglutaminase-like superfamily
GTU81_RS07825	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GTU81_RS07830	COG3187	Heat shock protein
GTU81_RS07835	COG0387	Pfam Sodium calcium exchanger
GTU81_RS07865	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
GTU81_RS07895	COG4932	domain protein
GTU81_RS07900	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GTU81_RS07915	COG1012	belongs to the aldehyde dehydrogenase family
GTU81_RS07920	COG3724	N-succinylarginine dihydrolase activity
GTU81_RS07925	COG2988	succinylglutamate desuccinylase activity
GTU81_RS07930	COG3678	ATP-independent chaperone mediated protein folding
GTU81_RS07935	COG0322	excinuclease ABC activity
GTU81_RS07940	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GTU81_RS07945	COG2814	Major facilitator Superfamily
GTU81_RS07950	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GTU81_RS07960	COG1823	symporter activity
GTU81_RS07965	COG1988	membrane-bound metal-dependent
GTU81_RS07975	COG3001	Fructosamine kinase
GTU81_RS07985	COG3137	Salt-induced outer membrane protein
GTU81_RS07990	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GTU81_RS08000	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GTU81_RS08005	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GTU81_RS08015	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GTU81_RS08025	COG0776	regulation of translation
GTU81_RS08035	COG0386	Belongs to the glutathione peroxidase family
GTU81_RS08040	COG0791	NLP P60 protein
GTU81_RS08055	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GTU81_RS08060	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GTU81_RS08065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GTU81_RS08070	COG4558	Periplasmic binding protein
GTU81_RS08075	COG3720	iron ion transport
GTU81_RS08085	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GTU81_RS08090	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GTU81_RS08090	COG0574	Belongs to the PEP-utilizing enzyme family
GTU81_RS08100	COG0628	permease
GTU81_RS08105	COG0247	lactate metabolic process
GTU81_RS08105	COG0277	FAD linked oxidase domain protein
GTU81_RS08115	COG0316	Belongs to the HesB IscA family
GTU81_RS08120	COG0719	Fe-S assembly protein
GTU81_RS08125	COG0396	ATPase activity
GTU81_RS08130	COG0719	Fe-S assembly protein
GTU81_RS08140	COG2166	iron-sulfur cluster assembly
GTU81_RS08150	COG0469	pyruvate kinase activity
GTU81_RS08170	COG0307	riboflavin synthase, alpha
GTU81_RS08175	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GTU81_RS08180	COG2814	Major facilitator Superfamily
GTU81_RS08185	COG0583	DNA-binding transcription factor activity
GTU81_RS08190	COG1609	Transcriptional regulator
GTU81_RS08195	COG0791	NLP P60 protein
GTU81_RS08200	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GTU81_RS08210	COG0346	lactoylglutathione lyase activity
GTU81_RS08215	COG1902	pentaerythritol trinitrate reductase activity
GTU81_RS08225	COG2194	sulfuric ester hydrolase activity
GTU81_RS08235	COG3313	Fe-S protein
GTU81_RS08255	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GTU81_RS08260	COG0259	pyridoxamine-phosphate oxidase activity
GTU81_RS08265	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GTU81_RS08275	COG0625	glutathione transferase activity
GTU81_RS08285	COG1309	transcriptional regulator
GTU81_RS08300	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GTU81_RS08305	COG4660	Part of a membrane complex involved in electron transport
GTU81_RS08310	COG4659	FMN binding
GTU81_RS08315	COG4658	electron transport chain
GTU81_RS08320	COG4656	Part of a membrane complex involved in electron transport
GTU81_RS08325	COG2878	Part of a membrane complex involved in electron transport
GTU81_RS08330	COG4657	Part of a membrane complex involved in electron transport
GTU81_RS08340	COG2160	L-arabinose isomerase activity
GTU81_RS08345	COG1069	ribulokinase activity
GTU81_RS08350	COG1879	ABC-type sugar transport system periplasmic component
GTU81_RS08360	COG1172	Belongs to the binding-protein-dependent transport system permease family
GTU81_RS08370	COG0673	inositol 2-dehydrogenase activity
GTU81_RS08375	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GTU81_RS08380	COG5339	Protein conserved in bacteria
GTU81_RS08400	COG2814	Major facilitator Superfamily
GTU81_RS08405	COG0583	DNA-binding transcription factor activity
GTU81_RS08410	COG1940	carbohydrate kinase activity
GTU81_RS08420	COG0477	Major facilitator Superfamily
GTU81_RS08435	COG4221	oxidoreductase activity
GTU81_RS08440	COG0402	S-adenosylhomocysteine deaminase activity
GTU81_RS08445	COG0339	signal peptide processing
GTU81_RS08460	COG2707	UPF0756 membrane protein
GTU81_RS08470	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GTU81_RS08475	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GTU81_RS08485	COG4771	TonB-dependent receptor
GTU81_RS08485	COG1629	transport
GTU81_RS08485	COG1629	transport
GTU81_RS08485	COG4771	TonB-dependent receptor
GTU81_RS08500	COG1309	transcriptional regulator
GTU81_RS08550	COG0840	transmembrane signaling receptor activity
GTU81_RS08590	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GTU81_RS08610	COG4290	ribonuclease
GTU81_RS08625	COG3708	Transcriptional regulator
GTU81_RS08625	COG2207	Transcriptional regulator
GTU81_RS08635	COG2814	Major facilitator Superfamily
GTU81_RS08665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GTU81_RS08675	COG0747	negative chemotaxis
GTU81_RS08680	COG2195	Cleaves the N-terminal amino acid of tripeptides
GTU81_RS08700	COG2814	Major facilitator Superfamily
GTU81_RS08720	COG2840	Smr protein MutS2
GTU81_RS08745	COG3182	Iron-regulated membrane protein
GTU81_RS08760	COG0531	amino acid
GTU81_RS08770	COG0745	RESPONSE REGULATOR receiver
GTU81_RS08785	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GTU81_RS08825	COG0582	viral genome integration into host DNA
GTU81_RS08830	COG2205	protein histidine kinase activity
GTU81_RS08835	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GTU81_RS08845	COG3591	Belongs to the peptidase S1B family
GTU81_RS08850	COG3023	N-Acetylmuramoyl-L-alanine amidase
GTU81_RS08855	COG1643	Atp-dependent helicase
GTU81_RS08860	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GTU81_RS08865	COG1028	Short-chain dehydrogenase reductase Sdr
GTU81_RS08870	COG3784	Protein of unknown function (DUF1318)
GTU81_RS08880	COG2911	Protein conserved in bacteria
GTU81_RS08885	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GTU81_RS08900	COG0513	Belongs to the DEAD box helicase family
GTU81_RS08905	COG0037	tRNA processing
GTU81_RS08910	COG0366	Alpha amylase catalytic
GTU81_RS08920	COG3539	Fimbrial protein
GTU81_RS08925	COG3121	Chaperone
GTU81_RS08930	COG3188	usher protein
GTU81_RS08950	COG4166	transmembrane transport
GTU81_RS08955	COG4948	Mandelate Racemase Muconate Lactonizing
GTU81_RS08970	COG3768	UPF0283 membrane protein
GTU81_RS08975	COG3106	COG3106 Predicted ATPase
GTU81_RS08985	COG1983	PspC domain protein
GTU81_RS08995	COG1842	Phage shock protein A
GTU81_RS09000	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GTU81_RS09010	COG4168	peptide transport system, permease
GTU81_RS09015	COG4171	peptide transport system, permease
GTU81_RS09020	COG4172	Belongs to the ABC transporter superfamily
GTU81_RS09025	COG4172	Belongs to the ABC transporter superfamily
GTU81_RS09035	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GTU81_RS09035	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GTU81_RS09060	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
GTU81_RS09065	COG0235	Class ii aldolase
GTU81_RS09080	COG0023	Translation Initiation Factor
GTU81_RS09085	COG0284	orotidine-5'-phosphate decarboxylase activity
GTU81_RS09090	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GTU81_RS09095	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
GTU81_RS09100	COG0671	phosphoesterase, PA-phosphatase related
GTU81_RS09110	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GTU81_RS09135	COG0616	signal peptide processing
GTU81_RS09140	COG1028	Short-chain dehydrogenase reductase Sdr
GTU81_RS09150	COG0009	L-threonylcarbamoyladenylate synthase
GTU81_RS09155	COG0613	PHP domain protein
GTU81_RS09165	COG0512	Glutamine amidotransferase of anthranilate synthase
GTU81_RS09165	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GTU81_RS09170	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GTU81_RS09180	COG0133	tryptophan synthase activity
GTU81_RS09185	COG0159	tryptophan synthase activity
GTU81_RS09195	COG3047	cAMP biosynthetic process
GTU81_RS09205	COG2917	probably involved in intracellular septation
GTU81_RS09220	COG2350	Protein conserved in bacteria
GTU81_RS09230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GTU81_RS09235	COG3099	Belongs to the UPF0263 family
GTU81_RS09245	COG0444	Belongs to the ABC transporter superfamily
GTU81_RS09250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GTU81_RS09255	COG0601	transmembrane transport
GTU81_RS09265	COG4166	transmembrane transport
GTU81_RS09270	COG2095	MarC family integral membrane protein
GTU81_RS09285	COG3384	dioxygenase
GTU81_RS09295	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GTU81_RS09300	COG0583	DNA-binding transcription factor activity
GTU81_RS09305	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GTU81_RS09310	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GTU81_RS09315	COG2828	Protein conserved in bacteria
GTU81_RS09365	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GTU81_RS09370	COG0745	RESPONSE REGULATOR receiver
GTU81_RS09375	COG3012	SEC-C Motif Domain Protein
GTU81_RS09380	COG0788	formyltetrahydrofolate deformylase activity
GTU81_RS09410	COG0708	Exodeoxyribonuclease III
GTU81_RS09425	COG0778	Nitroreductase
GTU81_RS09430	COG0616	signal peptide processing
GTU81_RS09435	COG0252	asparaginase activity
GTU81_RS09440	COG1335	isochorismatase
GTU81_RS09445	COG3139	Protein of unknown function (DUF1315)
GTU81_RS09450	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GTU81_RS09465	COG0656	L-ascorbic acid biosynthetic process
GTU81_RS09470	COG3713	MltA-interacting MipA family protein
GTU81_RS09475	COG2766	serine protein kinase
GTU81_RS09480	COG2718	Belongs to the UPF0229 family
GTU81_RS09505	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GTU81_RS09510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GTU81_RS09515	COG2719	SpoVR family
GTU81_RS09520	COG2186	Transcriptional regulator
GTU81_RS09535	COG0179	Fumarylacetoacetate (FAA) hydrolase
GTU81_RS09540	COG3100	YcgL domain-containing protein
GTU81_RS09545	COG0850	regulation of cytokinetic process
GTU81_RS09550	COG2894	cell division
GTU81_RS09555	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
GTU81_RS09565	COG0318	PFAM AMP-dependent synthetase and ligase
GTU81_RS09570	COG3065	identical protein binding
GTU81_RS09580	COG1199	ATP-dependent helicase activity
GTU81_RS09585	COG0251	oxidation-reduction process
GTU81_RS09590	COG3140	Belongs to the UPF0181 family
GTU81_RS09605	COG1760	l-serine dehydratase
GTU81_RS09610	COG1253	flavin adenine dinucleotide binding
GTU81_RS09615	COG2226	methyltransferase
GTU81_RS09645	COG0501	Belongs to the peptidase M48B family
GTU81_RS09655	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
GTU81_RS09660	COG1956	GAF domain-containing protein
GTU81_RS09665	COG2995	paraquat-inducible protein a
GTU81_RS09670	COG3008	intermembrane lipid transfer
GTU81_RS09675	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GTU81_RS09675	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GTU81_RS09690	COG0628	permease
GTU81_RS09735	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GTU81_RS09740	COG1770	oligopeptidase
GTU81_RS09750	COG3141	response to X-ray
GTU81_RS09755	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GTU81_RS09760	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GTU81_RS09765	COG0469	pyruvate kinase activity
GTU81_RS09775	COG1560	Kdo2-lipid A biosynthetic process
GTU81_RS09780	COG0739	heme binding
GTU81_RS09785	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GTU81_RS09795	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GTU81_RS09800	COG2255	four-way junction helicase activity
GTU81_RS09805	COG0632	four-way junction helicase activity
GTU81_RS09810	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GTU81_RS09815	COG0217	transcriptional regulatory protein
GTU81_RS09820	COG0494	nUDIX hydrolase
GTU81_RS09825	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GTU81_RS09830	COG1801	Protein of unknown function DUF72
GTU81_RS09835	COG3788	relative of glutathione S-transferase, MAPEG superfamily
GTU81_RS09840	COG2226	methyltransferase
GTU81_RS09845	COG0500	methyltransferase
GTU81_RS09855	COG3142	Participates in the control of copper homeostasis
GTU81_RS09860	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GTU81_RS09865	COG3102	Protein conserved in bacteria
GTU81_RS09870	COG0018	arginyl-trna synthetase
GTU81_RS09885	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GTU81_RS09895	COG0745	RESPONSE REGULATOR receiver
GTU81_RS09905	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GTU81_RS09910	COG0840	transmembrane signaling receptor activity
GTU81_RS09925	COG0835	chemotaxis
GTU81_RS09980	COG0113	porphobilinogen synthase activity
GTU81_RS09985	COG0431	NADPH-dependent FMN reductase
GTU81_RS09995	COG2244	polysaccharide biosynthetic process
GTU81_RS10000	COG1216	Glycosyl transferase, family 2
GTU81_RS10020	COG3381	protein complex oligomerization
GTU81_RS10045	COG0778	Nitroreductase
GTU81_RS10060	COG1702	phosphate starvation-inducible protein PhoH
GTU81_RS10085	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GTU81_RS10085	COG0506	proline dehydrogenase activity
GTU81_RS10085	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GTU81_RS10090	COG4763	Acyl-transferase
GTU81_RS10120	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GTU81_RS10125	COG1516	flagellar protein fliS
GTU81_RS10135	COG0366	Alpha amylase catalytic
GTU81_RS10150	COG5475	Uncharacterized small protein (DUF2158)
GTU81_RS10155	COG2354	Protein conserved in bacteria
GTU81_RS10165	COG3727	T/G mismatch-specific endonuclease activity
GTU81_RS10175	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GTU81_RS10180	COG1418	mRNA catabolic process
GTU81_RS10190	COG3228	Belongs to the MtfA family
GTU81_RS10200	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GTU81_RS10205	COG0803	Belongs to the bacterial solute-binding protein 9 family
GTU81_RS10210	COG1121	(ABC) transporter
GTU81_RS10215	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GTU81_RS10220	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GTU81_RS10250	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GTU81_RS10260	COG4172	Belongs to the ABC transporter superfamily
GTU81_RS10265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GTU81_RS10270	COG0601	transmembrane transport
GTU81_RS10275	COG0747	negative chemotaxis
GTU81_RS10320	COG1280	lysine exporter protein (LysE YggA)
GTU81_RS10325	COG0583	DNA-binding transcription factor activity
GTU81_RS10365	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GTU81_RS10370	COG1063	alcohol dehydrogenase
GTU81_RS10375	COG3284	Transcriptional regulator
GTU81_RS10385	COG1522	sequence-specific DNA binding
GTU81_RS10405	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GTU81_RS10410	COG0077	Prephenate dehydratase
GTU81_RS10425	COG1280	lysine exporter protein (LysE YggA)
GTU81_RS10430	COG0596	Alpha beta hydrolase
GTU81_RS10440	COG0534	Mate efflux family protein
GTU81_RS10445	COG2926	Belongs to the UPF0265 family
GTU81_RS10450	COG1289	transmembrane transporter activity
GTU81_RS10455	COG2925	Exonuclease
GTU81_RS10460	COG0531	amino acid
GTU81_RS10465	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GTU81_RS10475	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GTU81_RS10485	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GTU81_RS10490	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GTU81_RS10490	COG0131	Imidazoleglycerol-phosphate dehydratase
GTU81_RS10495	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GTU81_RS10500	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GTU81_RS10510	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GTU81_RS10510	COG0140	phosphoribosyl-ATP diphosphatase activity
GTU81_RS10515	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GTU81_RS10545	COG1442	glycosyl transferase family 8
GTU81_RS10580	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GTU81_RS10645	COG1253	flavin adenine dinucleotide binding
GTU81_RS10650	COG2982	Protein involved in outer membrane biogenesis
GTU81_RS10655	COG0717	Belongs to the dCTP deaminase family
GTU81_RS10660	COG0572	uridine kinase
GTU81_RS10670	COG5001	Diguanylate cyclase
GTU81_RS10670	COG5002	protein histidine kinase activity
GTU81_RS10670	COG3447	MASE1 domain protein
GTU81_RS10675	COG0443	Heat shock 70 kDa protein
GTU81_RS10700	COG2205	protein histidine kinase activity
GTU81_RS10705	COG0745	RESPONSE REGULATOR receiver
GTU81_RS10725	COG1597	lipid kinase activity
GTU81_RS10730	COG0351	phosphomethylpyrimidine kinase
GTU81_RS10735	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GTU81_RS10745	COG1605	Chorismate mutase
GTU81_RS10760	COG0489	protein tyrosine kinase activity
GTU81_RS10765	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GTU81_RS10765	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GTU81_RS10770	COG1380	Effector of murein hydrolase LrgA
GTU81_RS10780	COG0295	cytidine deaminase activity
GTU81_RS10785	COG0281	malic enzyme
GTU81_RS10790	COG2949	membrane
GTU81_RS10800	COG1129	ABC transporter
GTU81_RS10810	COG1609	Transcriptional regulator
GTU81_RS10815	COG2311	Membrane
GTU81_RS10820	COG0302	gtp cyclohydrolase
GTU81_RS10825	COG0583	DNA-binding transcription factor activity
GTU81_RS10845	COG1120	ATPase activity
GTU81_RS10850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GTU81_RS10860	COG0583	DNA-binding transcription factor activity
GTU81_RS10865	COG2855	membrane
GTU81_RS10870	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GTU81_RS10875	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GTU81_RS10875	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GTU81_RS10875	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GTU81_RS10880	COG1105	Belongs to the carbohydrate kinase PfkB family
GTU81_RS10885	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GTU81_RS10885	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GTU81_RS10895	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GTU81_RS10900	COG0671	phosphoesterase, PA-phosphatase related
GTU81_RS10905	COG0791	NLP P60 protein
GTU81_RS10910	COG2200	EAL domain
GTU81_RS10915	COG4166	transmembrane transport
GTU81_RS10920	COG4174	ABC transporter (Permease)
GTU81_RS10925	COG4239	(ABC) transporter, permease
GTU81_RS10930	COG4172	Belongs to the ABC transporter superfamily
GTU81_RS10940	COG2814	Major facilitator Superfamily
GTU81_RS10945	COG1187	pseudouridine synthase activity
GTU81_RS10950	COG1061	Type III restriction enzyme res subunit
GTU81_RS10955	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GTU81_RS10960	COG3081	Nucleoid-associated protein
GTU81_RS10965	COG3082	Protein of unknown function (DUF1414)
GTU81_RS10970	COG3083	sulfuric ester hydrolase activity
GTU81_RS11030	COG2977	Belongs to the P-Pant transferase superfamily
GTU81_RS11040	COG3145	DNA-N1-methyladenine dioxygenase activity
GTU81_RS11065	COG0642	Histidine kinase
GTU81_RS11065	COG2198	Histidine kinase
GTU81_RS11070	COG2197	response regulator
GTU81_RS11075	COG0784	Response regulator, receiver
GTU81_RS11075	COG2205	protein histidine kinase activity
GTU81_RS11085	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GTU81_RS11090	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GTU81_RS11100	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GTU81_RS11120	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
GTU81_RS11135	COG4575	ribosome binding
GTU81_RS11140	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
GTU81_RS11145	COG2153	protein acetylation
GTU81_RS11160	COG1007	ATP synthesis coupled electron transport
GTU81_RS11165	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GTU81_RS11170	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GTU81_RS11175	COG0713	ATP synthesis coupled electron transport
GTU81_RS11180	COG0839	Belongs to the complex I subunit 6 family
GTU81_RS11185	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GTU81_RS11190	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GTU81_RS11200	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GTU81_RS11210	COG0649	NAD binding
GTU81_RS11210	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GTU81_RS11215	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GTU81_RS11220	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GTU81_RS11225	COG0583	DNA-binding transcription factor activity
GTU81_RS11230	COG0436	Aminotransferase
GTU81_RS11235	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
GTU81_RS11255	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GTU81_RS11260	COG3092	negative regulation of chromosome organization
GTU81_RS11265	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GTU81_RS11270	COG0857	belongs to the CobB CobQ family
GTU81_RS11270	COG0280	phosphate acetyltransferase
GTU81_RS11275	COG3842	ATPase activity
GTU81_RS11285	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GTU81_RS11295	COG1176	ABC-type spermidine putrescine transport system, permease component I
GTU81_RS11300	COG1177	transmembrane transport
GTU81_RS11315	COG1090	epimerase
GTU81_RS11320	COG4598	ABC transporter
GTU81_RS11325	COG4160	amino acid transport
GTU81_RS11340	COG0163	prenyltransferase activity
GTU81_RS11345	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GTU81_RS11350	COG1286	toxin biosynthetic process
GTU81_RS11355	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GTU81_RS11360	COG0285	dihydrofolate synthase activity
GTU81_RS11375	COG0586	Pfam SNARE associated Golgi protein
GTU81_RS11385	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GTU81_RS11395	COG2207	Transcriptional regulator
GTU81_RS11440	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GTU81_RS11455	COG3101	peptidyl-lysine hydroxylation
GTU81_RS11460	COG0730	response to heat
GTU81_RS11470	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GTU81_RS11480	COG2840	Smr protein MutS2
GTU81_RS11485	COG2062	phosphohistidine phosphatase, SixA
GTU81_RS11490	COG1250	3-hydroxyacyl-CoA dehydrogenase
GTU81_RS11490	COG1024	Enoyl-CoA hydratase
GTU81_RS11495	COG0183	Belongs to the thiolase family
GTU81_RS11510	COG2067	long-chain fatty acid transport protein
GTU81_RS11520	COG4235	cytochrome complex assembly
GTU81_RS11520	COG3088	subunit of a heme lyase
GTU81_RS11525	COG3088	subunit of a heme lyase
GTU81_RS11525	COG4235	cytochrome complex assembly
GTU81_RS11535	COG1138	Cytochrome C-type biogenesis protein
GTU81_RS11540	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
GTU81_RS11545	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GTU81_RS11550	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GTU81_RS11555	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GTU81_RS11590	COG0668	transmembrane transport
GTU81_RS11630	COG0436	Aminotransferase
GTU81_RS11645	COG0837	glucose binding
GTU81_RS11650	COG3961	Belongs to the TPP enzyme family
GTU81_RS11655	COG0667	Aldo Keto reductase
GTU81_RS11665	COG1914	H( )-stimulated, divalent metal cation uptake system
GTU81_RS11670	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GTU81_RS11685	COG2116	formate transmembrane transporter activity
GTU81_RS11690	COG3415	Transposase
GTU81_RS11695	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GTU81_RS11740	COG0583	DNA-binding transcription factor activity
GTU81_RS11745	COG0385	Bile acid
GTU81_RS11750	COG3530	Putative quorum-sensing-regulated virulence factor
GTU81_RS11755	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GTU81_RS11760	COG3115	cell septum assembly
GTU81_RS11765	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
GTU81_RS11770	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GTU81_RS11780	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GTU81_RS11790	COG2205	protein histidine kinase activity
GTU81_RS11795	COG0745	RESPONSE REGULATOR receiver
GTU81_RS11805	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GTU81_RS11810	COG4208	sulfate ABC transporter
GTU81_RS11815	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
GTU81_RS11840	COG0860	N-Acetylmuramoyl-L-alanine amidase
GTU81_RS11845	COG0408	coproporphyrinogen oxidase activity
GTU81_RS11850	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GTU81_RS11855	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GTU81_RS11860	COG0494	nUDIX hydrolase
GTU81_RS11875	COG3850	Histidine kinase
GTU81_RS11880	COG2197	response regulator
GTU81_RS11885	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GTU81_RS11900	COG1393	Belongs to the ArsC family
GTU81_RS11905	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GTU81_RS11930	COG4104	PAAR repeat-containing protein
GTU81_RS11990	COG1444	tRNA N-acetyltransferase activity
GTU81_RS11995	COG2321	neutral zinc metallopeptidase
GTU81_RS12000	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GTU81_RS12005	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GTU81_RS12010	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GTU81_RS12015	COG2716	regulation of RNA biosynthetic process
GTU81_RS12020	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GTU81_RS12025	COG3706	GGDEF domain
GTU81_RS12030	COG4783	chaperone-mediated protein folding
GTU81_RS12035	COG1393	Belongs to the ArsC family
GTU81_RS12040	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GTU81_RS12045	COG2233	PERMEase
GTU81_RS12055	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GTU81_RS12060	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GTU81_RS12065	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GTU81_RS12070	COG0581	inorganic phosphate transmembrane transporter activity
GTU81_RS12075	COG0573	inorganic phosphate transmembrane transporter activity
GTU81_RS12080	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GTU81_RS12090	COG0500	methyltransferase
GTU81_RS12095	COG2200	EAL domain
GTU81_RS12100	COG2239	Acts as a magnesium transporter
GTU81_RS12105	COG2271	Major facilitator Superfamily
GTU81_RS12110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GTU81_RS12125	COG3122	Protein conserved in bacteria
GTU81_RS12160	COG0516	GMP reductase activity
GTU81_RS12160	COG0517	IMP dehydrogenase activity
GTU81_RS12165	COG1570	exodeoxyribonuclease VII activity
GTU81_RS12180	COG4993	Dehydrogenase
GTU81_RS12190	COG1160	GTP binding
GTU81_RS12195	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GTU81_RS12200	COG2976	Protein conserved in bacteria
GTU81_RS12205	COG0124	histidyl-tRNA synthetase
GTU81_RS12210	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GTU81_RS12215	COG1426	Protein conserved in bacteria
GTU81_RS12225	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GTU81_RS12230	COG0105	UTP biosynthetic process
GTU81_RS12235	COG2897	thiosulfate sulfurtransferase activity
GTU81_RS12245	COG1012	belongs to the aldehyde dehydrogenase family
GTU81_RS12250	COG0446	pyridine nucleotide-disulphide oxidoreductase
GTU81_RS12265	COG3938	Belongs to the proline racemase family
GTU81_RS12275	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GTU81_RS12280	COG0531	amino acid
GTU81_RS12290	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GTU81_RS12295	COG1104	cysteine desulfurase activity
GTU81_RS12300	COG1959	2 iron, 2 sulfur cluster binding
GTU81_RS12310	COG0483	inositol monophosphate 1-phosphatase activity
GTU81_RS12315	COG3711	transcriptional antiterminator
GTU81_RS12320	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GTU81_RS12325	COG0347	Belongs to the P(II) protein family
GTU81_RS12330	COG2204	response regulator
GTU81_RS12335	COG3170	Tfp pilus assembly protein FimV
GTU81_RS12340	COG2205	protein histidine kinase activity
GTU81_RS12345	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GTU81_RS12345	COG0047	phosphoribosylformylglycinamidine synthase activity
GTU81_RS12350	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GTU81_RS12360	COG0560	Phosphoserine phosphatase
GTU81_RS12365	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GTU81_RS12370	COG1737	Transcriptional regulator
GTU81_RS12380	COG0736	holo-[acyl-carrier-protein] synthase activity
GTU81_RS12385	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GTU81_RS12390	COG1381	Involved in DNA repair and RecF pathway recombination
GTU81_RS12400	COG0571	ribonuclease III activity
GTU81_RS12410	COG0481	GTPase activity
GTU81_RS12425	COG3086	response to oxidative stress
GTU81_RS12430	COG3026	antisigma factor binding
GTU81_RS12445	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GTU81_RS12450	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GTU81_RS12455	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GTU81_RS12460	COG0513	Belongs to the DEAD box helicase family
GTU81_RS12465	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GTU81_RS12470	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GTU81_RS12475	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GTU81_RS12480	COG0497	DNA recombination
GTU81_RS12485	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GTU81_RS12490	COG2914	Belongs to the UPF0125 (RnfH) family
GTU81_RS12495	COG2867	negative regulation of translational initiation
GTU81_RS12500	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GTU81_RS12525	COG0835	chemotaxis
GTU81_RS12530	COG2198	Histidine kinase
GTU81_RS12530	COG0643	Histidine kinase
GTU81_RS12560	COG0840	transmembrane signaling receptor activity
GTU81_RS12565	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GTU81_RS12575	COG1705	Flagellar rod assembly protein muramidase FlgJ
GTU81_RS12575	COG3951	Flagellar rod assembly protein muramidase FlgJ
GTU81_RS12585	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GTU81_RS12615	COG1815	bacterial-type flagellum-dependent cell motility
GTU81_RS12630	COG3418	PFAM FlgN family protein
GTU81_RS12675	COG4797	methyltransferase
GTU81_RS12675	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GTU81_RS12685	COG1987	bacterial-type flagellum assembly
GTU81_RS12695	COG3190	flagellar
GTU81_RS12700	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GTU81_RS12710	COG1580	Controls the rotational direction of flagella during chemotaxis
GTU81_RS12725	COG1157	protein secretion by the type III secretion system
GTU81_RS12730	COG1317	bacterial-type flagellum organization
GTU81_RS12745	COG1677	Flagellar hook-basal body complex protein FliE
GTU81_RS12750	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GTU81_RS12760	COG0745	RESPONSE REGULATOR receiver
GTU81_RS12775	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GTU81_RS12790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GTU81_RS12805	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GTU81_RS12810	COG1780	Probably involved in ribonucleotide reductase function
GTU81_RS12830	COG4176	ABC-type proline glycine betaine transport system permease component
GTU81_RS12835	COG2113	Glycine betaine
GTU81_RS12840	COG2814	Major facilitator Superfamily
GTU81_RS12845	COG1846	Transcriptional regulator
GTU81_RS12850	COG1566	PFAM secretion protein HlyD family protein
GTU81_RS12855	COG2814	Major facilitator Superfamily
GTU81_RS12860	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GTU81_RS12865	COG3118	belongs to the thioredoxin family
GTU81_RS12870	COG3148	PFAM DTW domain containing protein
GTU81_RS12875	COG1042	CoA-binding domain protein
GTU81_RS12875	COG0045	succinate-CoA ligase (ADP-forming) activity
GTU81_RS12875	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GTU81_RS12880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GTU81_RS12885	COG5544	Lipoprotein
GTU81_RS12890	COG0477	Major facilitator Superfamily
GTU81_RS12920	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GTU81_RS12925	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GTU81_RS12930	COG2011	ABC-type metal ion transport system permease component
GTU81_RS12935	COG1464	Belongs to the NlpA lipoprotein family
GTU81_RS12945	COG1720	tRNA m6t6A37 methyltransferase activity
GTU81_RS12950	COG0442	prolyl-tRNA aminoacylation
GTU81_RS12975	COG4568	rho-dependent transcription termination
GTU81_RS12985	COG0037	tRNA processing
GTU81_RS12990	COG0346	lactoylglutathione lyase activity
GTU81_RS12995	COG1982	Orn Lys Arg decarboxylase major
GTU81_RS13000	COG0825	malonyl-CoA metabolic process
GTU81_RS13010	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GTU81_RS13015	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GTU81_RS13020	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GTU81_RS13025	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GTU81_RS13030	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GTU81_RS13035	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
GTU81_RS13040	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GTU81_RS13045	COG0750	zinc metalloprotease
GTU81_RS13050	COG0575	Belongs to the CDS family
GTU81_RS13055	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GTU81_RS13060	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GTU81_RS13065	COG0233	cytoplasmic translational termination
GTU81_RS13070	COG0528	UMP kinase activity
GTU81_RS13075	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GTU81_RS13080	COG0052	Belongs to the universal ribosomal protein uS2 family
GTU81_RS13090	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GTU81_RS13095	COG2171	N-acyltransferase activity
GTU81_RS13105	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GTU81_RS13115	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GTU81_RS13125	COG0316	Belongs to the HesB IscA family
GTU81_RS13130	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GTU81_RS13140	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GTU81_RS13145	COG1120	ATPase activity
GTU81_RS13160	COG2026	Addiction module toxin, RelE StbE family
GTU81_RS13165	COG3077	Addiction module antitoxin, RelB DinJ family
GTU81_RS13190	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GTU81_RS13195	COG1643	Atp-dependent helicase
GTU81_RS13200	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GTU81_RS13205	COG1489	DNA binding
GTU81_RS13225	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GTU81_RS13230	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GTU81_RS13235	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GTU81_RS13240	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GTU81_RS13245	COG0842	Transport permease protein
GTU81_RS13250	COG1131	(ABC) transporter
GTU81_RS13255	COG0288	reversible hydration of carbon dioxide
GTU81_RS13260	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GTU81_RS13290	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GTU81_RS13295	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GTU81_RS13300	COG3112	Uncharacterised protein family (UPF0231)
GTU81_RS13320	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GTU81_RS13325	COG1518	maintenance of DNA repeat elements
GTU81_RS13340	COG1857	crispr-associated protein
GTU81_RS13355	COG1203	CRISPR-associated helicase, Cas3
GTU81_RS13360	COG2175	clavaminate synthase activity
GTU81_RS13370	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
GTU81_RS13375	COG1024	Enoyl-CoA hydratase
GTU81_RS13380	COG0183	Belongs to the thiolase family
GTU81_RS13385	COG0318	PFAM AMP-dependent synthetase and ligase
GTU81_RS13400	COG1268	BioY protein
GTU81_RS13405	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GTU81_RS13410	COG1122	ATPase activity
GTU81_RS13415	COG1028	Short-chain dehydrogenase reductase Sdr
GTU81_RS13420	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GTU81_RS13425	COG0508	dehydrogenase complex catalyzes the overall conversion of
GTU81_RS13430	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GTU81_RS13435	COG2186	Transcriptional regulator
GTU81_RS13440	COG1113	amino acid transport
GTU81_RS13445	COG2211	Major facilitator Superfamily
GTU81_RS13450	COG3940	Belongs to the glycosyl hydrolase 43 family
GTU81_RS13475	COG3725	Membrane protein required for beta-lactamase induction
GTU81_RS13490	COG4969	Belongs to the N-Me-Phe pilin family
GTU81_RS13495	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GTU81_RS13500	COG1459	type II secretion system
GTU81_RS13505	COG0516	GMP reductase activity
GTU81_RS13515	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
GTU81_RS13520	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GTU81_RS13525	COG0494	nUDIX hydrolase
GTU81_RS13600	COG3397	chitin binding
GTU81_RS13610	COG0653	protein targeting
GTU81_RS13625	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GTU81_RS13630	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GTU81_RS13635	COG0849	cell division
GTU81_RS13645	COG1181	Belongs to the D-alanine--D-alanine ligase family
GTU81_RS13655	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GTU81_RS13660	COG0772	Belongs to the SEDS family
GTU81_RS13670	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GTU81_RS13675	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GTU81_RS13680	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GTU81_RS13685	COG0768	penicillin binding
GTU81_RS13690	COG3116	cell division
GTU81_RS13695	COG0275	rRNA processing
GTU81_RS13700	COG2001	Belongs to the MraZ family
GTU81_RS13715	COG0028	Belongs to the TPP enzyme family
GTU81_RS13725	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GTU81_RS13730	COG0473	3-isopropylmalate dehydrogenase activity
GTU81_RS13740	COG0066	3-isopropylmalate dehydratase activity
GTU81_RS13745	COG2814	Major facilitator Superfamily
GTU81_RS13750	COG4533	DNA binding
GTU81_RS13755	COG4143	(ABC) transporter
GTU81_RS13760	COG1178	ABC-type Fe3 transport system permease component
GTU81_RS13765	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
GTU81_RS13770	COG0586	Pfam SNARE associated Golgi protein
GTU81_RS13775	COG0417	DNA replication proofreading
GTU81_RS13780	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GTU81_RS13785	COG0564	pseudouridine synthase activity
GTU81_RS13790	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GTU81_RS13805	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GTU81_RS13810	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GTU81_RS13815	COG2967	ApaG domain
GTU81_RS13820	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GTU81_RS13825	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GTU81_RS13830	COG1280	lysine exporter protein (LysE YggA)
GTU81_RS13840	COG0505	Belongs to the CarA family
GTU81_RS13845	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GTU81_RS13850	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GTU81_RS13855	COG1047	Peptidyl-prolyl cis-trans
GTU81_RS13860	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GTU81_RS13865	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GTU81_RS13870	COG0196	riboflavin kinase activity
GTU81_RS13875	COG0268	Binds directly to 16S ribosomal RNA
GTU81_RS13880	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GTU81_RS13885	COG0484	heat shock protein binding
GTU81_RS13890	COG0443	Heat shock 70 kDa protein
GTU81_RS13900	COG0521	Mo-molybdopterin cofactor biosynthetic process
GTU81_RS13910	COG3022	response to hydroperoxide
GTU81_RS13920	COG0083	homoserine kinase activity
GTU81_RS13935	COG0745	RESPONSE REGULATOR receiver
GTU81_RS13940	COG3045	CreA protein
GTU81_RS13945	COG2207	Transcriptional regulator
GTU81_RS13945	COG3708	Transcriptional regulator
GTU81_RS13955	COG0406	alpha-ribazole phosphatase activity
GTU81_RS13960	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
GTU81_RS13965	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
GTU81_RS13970	COG0741	lytic transglycosylase activity
GTU81_RS13980	COG1349	DNA-binding transcription factor activity
GTU81_RS13990	COG0488	(ABC) transporter
GTU81_RS13995	COG0583	DNA-binding transcription factor activity
GTU81_RS14000	COG0604	alcohol dehydrogenase
GTU81_RS14025	COG0560	Phosphoserine phosphatase
GTU81_RS14030	COG3726	membrane protein affecting hemolysin expression
GTU81_RS14035	COG3550	peptidyl-serine autophosphorylation
GTU81_RS14040	COG0813	purine-nucleoside phosphorylase activity
GTU81_RS14045	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GTU81_RS14050	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GTU81_RS14055	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GTU81_RS14060	COG0084	hydrolase, TatD family'
GTU81_RS14065	COG4667	esterase of the alpha-beta hydrolase superfamily
GTU81_RS14070	COG5487	UPF0391 membrane protein
GTU81_RS14075	COG2823	Periplasmic or secreted lipoprotein
GTU81_RS14080	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GTU81_RS14085	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GTU81_RS14085	COG2755	lipolytic protein G-D-S-L family
GTU81_RS14090	COG2818	Glycosylase
GTU81_RS14095	COG1397	ADP-ribosylglycohydrolase
GTU81_RS14130	COG3209	COG3209 Rhs family protein
GTU81_RS14280	COG1011	Hydrolase
GTU81_RS14285	COG0456	acetyltransferase
GTU81_RS14290	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
GTU81_RS14295	COG2813	Specifically methylates the guanine in position
GTU81_RS14320	COG3706	GGDEF domain
GTU81_RS14345	COG1609	Transcriptional regulator
GTU81_RS14350	COG0477	Major facilitator Superfamily
GTU81_RS14410	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GTU81_RS14410	COG0517	IMP dehydrogenase activity
GTU81_RS14415	COG1349	DNA-binding transcription factor activity
GTU81_RS14420	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
GTU81_RS14425	COG1028	Short-chain dehydrogenase reductase Sdr
GTU81_RS14430	COG3731	PTS system glucitol sorbitol-specific IIA component
GTU81_RS14455	COG0535	radical SAM domain protein
GTU81_RS14465	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
GTU81_RS14470	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GTU81_RS14485	COG0659	secondary active sulfate transmembrane transporter activity
GTU81_RS14490	COG0288	reversible hydration of carbon dioxide
GTU81_RS14500	COG1902	pentaerythritol trinitrate reductase activity
GTU81_RS14500	COG0446	pyridine nucleotide-disulphide oxidoreductase
GTU81_RS14505	COG2813	Specifically methylates the guanine in position
GTU81_RS14510	COG1451	nucleotide metabolic process
GTU81_RS14515	COG2223	nitrite transmembrane transporter activity
GTU81_RS14520	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GTU81_RS14525	COG1063	alcohol dehydrogenase
GTU81_RS14530	COG0038	chloride channel
GTU81_RS14535	COG0861	Integral membrane protein TerC family
GTU81_RS14540	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GTU81_RS14550	COG0586	Pfam SNARE associated Golgi protein
GTU81_RS14560	COG1422	Protein of unknown function (DUF1090)
GTU81_RS14565	COG4575	ribosome binding
GTU81_RS14570	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
GTU81_RS14580	COG2259	Doxx family
GTU81_RS14590	COG0583	DNA-binding transcription factor activity
GTU81_RS14595	COG1741	Belongs to the pirin family
GTU81_RS14610	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GTU81_RS14615	COG3107	peptidoglycan biosynthetic process
GTU81_RS14620	COG0792	nuclease activity
GTU81_RS14625	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GTU81_RS14630	COG2823	Periplasmic or secreted lipoprotein
GTU81_RS14635	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GTU81_RS14635	COG3711	transcriptional antiterminator
GTU81_RS14650	COG3964	amidohydrolase
GTU81_RS14685	COG0312	modulator of DNA gyrase
GTU81_RS14690	COG3028	Belongs to the UPF0307 family
GTU81_RS14695	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GTU81_RS14700	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GTU81_RS14705	COG0840	transmembrane signaling receptor activity
GTU81_RS14715	COG2105	PFAM AIG2 family protein
GTU81_RS14725	COG0729	surface antigen
GTU81_RS14730	COG1253	flavin adenine dinucleotide binding
GTU81_RS14740	COG1218	3'(2'),5'-bisphosphate nucleotidase
GTU81_RS14750	COG0545	Peptidyl-prolyl cis-trans isomerase
GTU81_RS14755	COG3061	Opacity-associated protein A
GTU81_RS14760	COG0359	binds to the 23S rRNA
GTU81_RS14765	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GTU81_RS14770	COG2965	DNA replication, synthesis of RNA primer
GTU81_RS14775	COG0360	Binds together with S18 to 16S ribosomal RNA
GTU81_RS14780	COG1073	alpha beta
GTU81_RS14785	COG0840	transmembrane signaling receptor activity
GTU81_RS14795	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GTU81_RS14800	COG0557	exoribonuclease II activity
GTU81_RS14805	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GTU81_RS14810	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
GTU81_RS14815	COG0330	HflC and HflK could
GTU81_RS14820	COG0330	HflC and HflK could
GTU81_RS14825	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GTU81_RS14835	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GTU81_RS14840	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GTU81_RS14845	COG0860	N-Acetylmuramoyl-L-alanine amidase
GTU81_RS14850	COG0802	atpase or kinase
GTU81_RS14855	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GTU81_RS14855	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GTU81_RS14880	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GTU81_RS14885	COG1162	GTPase activity
GTU81_RS14890	COG0688	phosphatidylethanolamine metabolic process
GTU81_RS14895	COG3264	Mechanosensitive ion channel
GTU81_RS14895	COG1511	domain protein
GTU81_RS14900	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
GTU81_RS14905	COG3040	lipid binding
GTU81_RS14920	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GTU81_RS14925	COG1509	lysine 2,3-aminomutase activity
GTU81_RS14935	COG0459	protein refolding
GTU81_RS14940	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GTU81_RS14945	COG3030	protein affecting phage T7 exclusion by the F plasmid
GTU81_RS14950	COG1027	Aspartate ammonia-lyase
GTU81_RS14955	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GTU81_RS14965	COG1309	transcriptional regulator
GTU81_RS14980	COG2211	Major facilitator Superfamily
GTU81_RS14990	COG0367	asparagine synthase
GTU81_RS15005	COG0124	histidyl-tRNA synthetase
GTU81_RS15020	COG2890	protein-(glutamine-N5) methyltransferase activity
GTU81_RS15030	COG1181	Belongs to the D-alanine--D-alanine ligase family
GTU81_RS15205	COG0076	glutamate decarboxylase activity
GTU81_RS15210	COG3486	L-lysine 6-monooxygenase (NADPH) activity
GTU81_RS15220	COG4774	siderophore transport
GTU81_RS15230	COG1028	Short-chain dehydrogenase reductase Sdr
GTU81_RS15240	COG1902	pentaerythritol trinitrate reductase activity
GTU81_RS15250	COG0561	phosphatase activity
GTU81_RS15255	COG5383	Protein conserved in bacteria
GTU81_RS15260	COG2382	esterase
GTU81_RS15270	COG1280	lysine exporter protein (LysE YggA)
GTU81_RS15275	COG0583	DNA-binding transcription factor activity
GTU81_RS15290	COG0583	DNA-binding transcription factor activity
GTU81_RS15305	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GTU81_RS15325	COG5001	Diguanylate cyclase
GTU81_RS15325	COG3300	MHYT domain
GTU81_RS15330	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
GTU81_RS15350	COG0840	transmembrane signaling receptor activity
GTU81_RS15355	COG1301	dicarboxylic acid transport
GTU81_RS15365	COG3162	membrane
GTU81_RS15370	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GTU81_RS15380	COG1346	cytolysis
GTU81_RS15385	COG1380	Effector of murein hydrolase LrgA
GTU81_RS15390	COG0583	DNA-binding transcription factor activity
GTU81_RS15395	COG0025	NhaP-type Na H and K H
GTU81_RS15400	COG2252	PERMEase
GTU81_RS15405	COG0625	glutathione transferase activity
GTU81_RS15435	COG2831	hemolysin activation secretion protein
GTU81_RS15440	COG0629	single-stranded DNA binding
GTU81_RS15445	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GTU81_RS15450	COG1064	alcohol dehydrogenase
GTU81_RS15455	COG1388	LysM domain
GTU81_RS15455	COG1470	cell adhesion involved in biofilm formation
GTU81_RS15460	COG2315	Protein conserved in bacteria
GTU81_RS15470	COG1448	Aminotransferase
GTU81_RS15495	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GTU81_RS15510	COG2246	polysaccharide biosynthetic process
GTU81_RS15575	COG1403	HNH endonuclease
GTU81_RS15595	COG0735	belongs to the Fur family
GTU81_RS15600	COG3237	CsbD-like
GTU81_RS15605	COG0534	Mate efflux family protein
GTU81_RS15610	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GTU81_RS15615	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GTU81_RS15630	COG3161	chorismate lyase activity
GTU81_RS15635	COG3223	Belongs to the PsiE family
GTU81_RS15640	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GTU81_RS15660	COG0166	Belongs to the GPI family
GTU81_RS15665	COG0527	aspartate kinase activity
GTU81_RS15670	COG1283	sodium-dependent phosphate transmembrane transporter activity
GTU81_RS15675	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GTU81_RS15700	COG0138	bifunctional purine biosynthesis protein purh
GTU81_RS15705	COG0151	Belongs to the GarS family
GTU81_RS15725	COG1515	deoxyribonuclease V activity
GTU81_RS15730	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GTU81_RS15735	COG2816	NAD+ diphosphatase activity
GTU81_RS15740	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
GTU81_RS15745	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GTU81_RS15755	COG4571	Outer membrane protease
GTU81_RS15800	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GTU81_RS15805	COG0085	RNA polymerase activity
GTU81_RS15810	COG0222	ribosome binding
GTU81_RS15815	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GTU81_RS15820	COG0081	regulation of translation
GTU81_RS15825	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GTU81_RS15830	COG0250	Participates in transcription elongation, termination and antitermination
GTU81_RS15865	COG1072	(Pantothenic acid kinase))
GTU81_RS15870	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GTU81_RS15870	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GTU81_RS15905	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
GTU81_RS15910	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GTU81_RS15915	COG1739	Uncharacterized protein family UPF0029
GTU81_RS15920	COG0006	proline dipeptidase activity
GTU81_RS15930	COG0183	Belongs to the thiolase family
GTU81_RS15940	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GTU81_RS15955	COG0805	protein transport
GTU81_RS15960	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GTU81_RS15970	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GTU81_RS15980	COG2226	methyltransferase
GTU81_RS15985	COG1322	Protein conserved in bacteria
GTU81_RS15995	COG0412	Dienelactone hydrolase
GTU81_RS16000	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GTU81_RS16005	COG0583	DNA-binding transcription factor activity
GTU81_RS16010	COG4807	Protein conserved in bacteria
GTU81_RS16015	COG2271	Major facilitator Superfamily
GTU81_RS16020	COG0561	phosphatase activity
GTU81_RS16025	COG2267	carboxylic ester hydrolase activity
GTU81_RS16030	COG1280	lysine exporter protein (LysE YggA)
GTU81_RS16035	COG0514	ATP-dependent DNA helicase (RecQ)
GTU81_RS16040	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
GTU81_RS16045	COG2050	protein possibly involved in aromatic compounds catabolism
GTU81_RS16050	COG0598	Magnesium transport protein CorA
GTU81_RS16055	COG0210	DNA helicase
GTU81_RS16060	COG1011	Hydrolase
GTU81_RS16070	COG3159	Protein conserved in bacteria
GTU81_RS16075	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GTU81_RS16085	COG3072	Adenylate cyclase
GTU81_RS16090	COG0181	hydroxymethylbilane synthase activity
GTU81_RS16095	COG1587	Uroporphyrinogen-III synthase
GTU81_RS16100	COG2959	enzyme of heme biosynthesis
GTU81_RS16105	COG3071	HemY protein
GTU81_RS16155	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
GTU81_RS16165	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GTU81_RS16170	COG2244	polysaccharide biosynthetic process
GTU81_RS16175	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GTU81_RS16180	COG0456	acetyltransferase
GTU81_RS16185	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GTU81_RS16190	COG1088	dTDP-glucose 4,6-dehydratase activity
GTU81_RS16195	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GTU81_RS16200	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GTU81_RS16210	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GTU81_RS16215	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GTU81_RS16220	COG3118	belongs to the thioredoxin family
GTU81_RS16225	COG0513	Belongs to the DEAD box helicase family
GTU81_RS16230	COG0248	Ppx GppA phosphatase
GTU81_RS16245	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GTU81_RS16255	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GTU81_RS16260	COG0129	dihydroxy-acid dehydratase activity
GTU81_RS16270	COG3978	acetolactate synthase activity
GTU81_RS16285	COG0606	chelatase, subunit chli
GTU81_RS16290	COG3085	chromosome segregation
GTU81_RS16295	COG0583	DNA-binding transcription factor activity
GTU81_RS16335	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GTU81_RS16340	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GTU81_RS16350	COG1309	transcriptional regulator
GTU81_RS16355	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GTU81_RS16365	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GTU81_RS16365	COG0678	peroxiredoxin activity
GTU81_RS16370	COG0165	Argininosuccinate lyase
GTU81_RS16375	COG0137	argininosuccinate synthase activity
GTU81_RS16385	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GTU81_RS16390	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GTU81_RS16400	COG0460	homoserine dehydrogenase
GTU81_RS16400	COG0527	aspartate kinase activity
GTU81_RS16405	COG0626	cystathionine gamma-synthase activity
GTU81_RS16410	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
GTU81_RS16415	COG0254	rRNA binding
GTU81_RS16420	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GTU81_RS16425	COG1609	Transcriptional regulator
GTU81_RS16430	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GTU81_RS16435	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GTU81_RS16440	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GTU81_RS16445	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GTU81_RS16450	COG3074	FtsZ-dependent cytokinesis
GTU81_RS16455	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GTU81_RS16470	COG1494	fructose-1,6-bisphosphatase
GTU81_RS16475	COG2814	Major facilitator Superfamily
GTU81_RS16490	COG3152	Membrane
GTU81_RS16500	COG0149	triose-phosphate isomerase activity
GTU81_RS16525	COG1295	ribonuclease BN
GTU81_RS16535	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GTU81_RS16540	COG0205	6-phosphofructokinase activity
GTU81_RS16550	COG3678	ATP-independent chaperone mediated protein folding
GTU81_RS16555	COG0745	RESPONSE REGULATOR receiver
GTU81_RS16560	COG2205	protein histidine kinase activity
GTU81_RS16565	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GTU81_RS16575	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GTU81_RS16580	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
GTU81_RS16585	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GTU81_RS16590	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GTU81_RS16595	COG4942	peptidase
GTU81_RS16600	COG2861	carbohydrate metabolic process
GTU81_RS16605	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GTU81_RS16610	COG0859	PFAM glycosyl transferase family 9
GTU81_RS16615	COG0859	PFAM glycosyl transferase family 9
GTU81_RS16620	COG0438	transferase activity, transferring glycosyl groups
GTU81_RS16625	COG3307	-O-antigen
GTU81_RS16630	COG1215	transferase activity, transferring glycosyl groups
GTU81_RS16645	COG0859	PFAM glycosyl transferase family 9
GTU81_RS16655	COG0438	transferase activity, transferring glycosyl groups
GTU81_RS16660	COG0859	PFAM glycosyl transferase family 9
GTU81_RS16665	COG1519	Transferase
GTU81_RS16675	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GTU81_RS16680	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GTU81_RS16690	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GTU81_RS16695	COG2003	Belongs to the UPF0758 family
GTU81_RS16700	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GTU81_RS16705	COG0756	dUTP diphosphatase activity
GTU81_RS16710	COG1309	transcriptional regulator
GTU81_RS16715	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GTU81_RS16720	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GTU81_RS16725	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GTU81_RS16735	COG1561	YicC-like family, N-terminal region
GTU81_RS16750	COG1401	restriction endodeoxyribonuclease activity
GTU81_RS16805	COG2824	Alkylphosphonate utilization operon protein PhnA
GTU81_RS16815	COG2197	response regulator
GTU81_RS16820	COG2860	membrane
GTU81_RS16830	COG0194	GDP metabolic process
GTU81_RS16835	COG1758	RNA polymerase activity
GTU81_RS16840	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GTU81_RS16845	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GTU81_RS16850	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GTU81_RS16855	COG2233	PERMEase
GTU81_RS16860	COG2982	Protein involved in outer membrane biogenesis
GTU81_RS16865	COG1187	pseudouridine synthase activity
GTU81_RS16870	COG0456	acetyltransferase
GTU81_RS16875	COG1490	D-aminoacyl-tRNA deacylase activity
GTU81_RS16885	COG1011	Hydrolase
GTU81_RS16905	COG3852	Histidine kinase
GTU81_RS16920	COG3078	GTPase activator activity
GTU81_RS16930	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GTU81_RS16930	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GTU81_RS16945	COG3084	Protein conserved in bacteria
GTU81_RS16950	COG0746	molybdenum cofactor guanylyltransferase activity
GTU81_RS16980	COG0477	Major facilitator Superfamily
GTU81_RS16985	COG1609	Transcriptional regulator
GTU81_RS16990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GTU81_RS16995	COG1879	ABC-type sugar transport system periplasmic component
GTU81_RS17000	COG1172	Belongs to the binding-protein-dependent transport system permease family
GTU81_RS17005	COG1129	ABC transporter
GTU81_RS17030	COG3111	PFAM Bacterial OB fold (BOF) protein
GTU81_RS17050	COG3158	transport of potassium into the cell
GTU81_RS17060	COG2425	protein containing a von Willebrand factor type A (vWA) domain
GTU81_RS17070	COG1522	sequence-specific DNA binding
GTU81_RS17075	COG0716	FMN binding
GTU81_RS17085	COG0357	Ribosomal RNA small subunit methyltransferase G
GTU81_RS17090	COG3312	ion transport
GTU81_RS17095	COG0356	it plays a direct role in the translocation of protons across the membrane
GTU81_RS17105	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GTU81_RS17110	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GTU81_RS17115	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GTU81_RS17120	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GTU81_RS17125	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GTU81_RS17130	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GTU81_RS17135	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GTU81_RS17140	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GTU81_RS17160	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GTU81_RS17165	COG0573	inorganic phosphate transmembrane transporter activity
GTU81_RS17170	COG0581	inorganic phosphate transmembrane transporter activity
GTU81_RS17175	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GTU81_RS17180	COG0704	Plays a role in the regulation of phosphate uptake
GTU81_RS17185	COG2814	Major facilitator Superfamily
GTU81_RS17195	COG2252	PERMEase
GTU81_RS17200	COG2091	lysine biosynthetic process via aminoadipic acid
GTU81_RS17205	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GTU81_RS17210	COG0706	membrane insertase activity
GTU81_RS17220	COG0594	ribonuclease P activity
GTU81_RS17225	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GTU81_RS17245	COG0583	DNA-binding transcription factor activity
GTU81_RS17250	COG1012	belongs to the aldehyde dehydrogenase family
GTU81_RS17260	COG4628	conserved protein (DUF2132)
GTU81_RS17325	COG1192	Involved in chromosome partitioning
GTU81_RS17335	COG0500	methyltransferase
GTU81_RS17340	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GTU81_RS17360	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine