locus-tag	class	description
EGZ89_RS00005	COG0716	FMN binding
EGZ89_RS00010	COG1522	sequence-specific DNA binding
EGZ89_RS00020	COG2425	protein containing a von Willebrand factor type A (vWA) domain
EGZ89_RS00030	COG3158	transport of potassium into the cell
EGZ89_RS00050	COG3111	PFAM Bacterial OB fold (BOF) protein
EGZ89_RS00075	COG1129	ABC transporter
EGZ89_RS00080	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGZ89_RS00085	COG1879	ABC-type sugar transport system periplasmic component
EGZ89_RS00090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGZ89_RS00095	COG1609	Transcriptional regulator
EGZ89_RS00100	COG0477	Major facilitator Superfamily
EGZ89_RS00130	COG0746	molybdenum cofactor guanylyltransferase activity
EGZ89_RS00135	COG3084	Protein conserved in bacteria
EGZ89_RS00150	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EGZ89_RS00150	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EGZ89_RS00160	COG3078	GTPase activator activity
EGZ89_RS00175	COG3852	Histidine kinase
EGZ89_RS00190	COG1011	Hydrolase
EGZ89_RS00200	COG1490	D-aminoacyl-tRNA deacylase activity
EGZ89_RS00205	COG0456	acetyltransferase
EGZ89_RS00210	COG1187	pseudouridine synthase activity
EGZ89_RS00215	COG2982	Protein involved in outer membrane biogenesis
EGZ89_RS00220	COG2233	PERMEase
EGZ89_RS00225	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EGZ89_RS00230	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EGZ89_RS00235	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EGZ89_RS00240	COG1758	RNA polymerase activity
EGZ89_RS00245	COG0194	GDP metabolic process
EGZ89_RS00255	COG2860	membrane
EGZ89_RS00260	COG2197	response regulator
EGZ89_RS00270	COG2824	Alkylphosphonate utilization operon protein PhnA
EGZ89_RS00325	COG1401	restriction endodeoxyribonuclease activity
EGZ89_RS00340	COG1561	YicC-like family, N-terminal region
EGZ89_RS00350	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EGZ89_RS00355	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EGZ89_RS00360	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EGZ89_RS00365	COG1309	transcriptional regulator
EGZ89_RS00370	COG0756	dUTP diphosphatase activity
EGZ89_RS00375	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EGZ89_RS00380	COG2003	Belongs to the UPF0758 family
EGZ89_RS00385	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EGZ89_RS00395	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EGZ89_RS00400	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EGZ89_RS00410	COG1519	Transferase
EGZ89_RS00415	COG0859	PFAM glycosyl transferase family 9
EGZ89_RS00420	COG0438	transferase activity, transferring glycosyl groups
EGZ89_RS00430	COG0859	PFAM glycosyl transferase family 9
EGZ89_RS00445	COG1215	transferase activity, transferring glycosyl groups
EGZ89_RS00450	COG3307	-O-antigen
EGZ89_RS00455	COG0438	transferase activity, transferring glycosyl groups
EGZ89_RS00460	COG0859	PFAM glycosyl transferase family 9
EGZ89_RS00465	COG0859	PFAM glycosyl transferase family 9
EGZ89_RS00470	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGZ89_RS00475	COG2861	carbohydrate metabolic process
EGZ89_RS00480	COG4942	peptidase
EGZ89_RS00485	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EGZ89_RS00490	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EGZ89_RS00495	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EGZ89_RS00500	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EGZ89_RS00510	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EGZ89_RS00515	COG2205	protein histidine kinase activity
EGZ89_RS00520	COG0745	RESPONSE REGULATOR receiver
EGZ89_RS00525	COG3678	ATP-independent chaperone mediated protein folding
EGZ89_RS00535	COG0205	6-phosphofructokinase activity
EGZ89_RS00540	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EGZ89_RS00550	COG1295	ribonuclease BN
EGZ89_RS00575	COG0149	triose-phosphate isomerase activity
EGZ89_RS00585	COG3152	Membrane
EGZ89_RS00600	COG2814	Major facilitator Superfamily
EGZ89_RS00605	COG1494	fructose-1,6-bisphosphatase
EGZ89_RS00620	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EGZ89_RS00625	COG3074	FtsZ-dependent cytokinesis
EGZ89_RS00630	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EGZ89_RS00635	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EGZ89_RS00640	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EGZ89_RS00645	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EGZ89_RS00650	COG1609	Transcriptional regulator
EGZ89_RS00655	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EGZ89_RS00660	COG0254	rRNA binding
EGZ89_RS00665	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
EGZ89_RS00670	COG0626	cystathionine gamma-synthase activity
EGZ89_RS00675	COG0460	homoserine dehydrogenase
EGZ89_RS00675	COG0527	aspartate kinase activity
EGZ89_RS00685	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EGZ89_RS00690	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EGZ89_RS00700	COG0137	argininosuccinate synthase activity
EGZ89_RS00705	COG0165	Argininosuccinate lyase
EGZ89_RS00710	COG0678	peroxiredoxin activity
EGZ89_RS00710	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EGZ89_RS00720	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGZ89_RS00725	COG1309	transcriptional regulator
EGZ89_RS00735	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EGZ89_RS00740	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EGZ89_RS00775	COG0583	DNA-binding transcription factor activity
EGZ89_RS00780	COG3085	chromosome segregation
EGZ89_RS00785	COG0606	chelatase, subunit chli
EGZ89_RS00800	COG3978	acetolactate synthase activity
EGZ89_RS00810	COG0129	dihydroxy-acid dehydratase activity
EGZ89_RS00815	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EGZ89_RS00825	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EGZ89_RS00840	COG0248	Ppx GppA phosphatase
EGZ89_RS00845	COG0513	Belongs to the DEAD box helicase family
EGZ89_RS00850	COG3118	belongs to the thioredoxin family
EGZ89_RS00855	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EGZ89_RS00860	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EGZ89_RS00870	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EGZ89_RS00875	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EGZ89_RS00880	COG1088	dTDP-glucose 4,6-dehydratase activity
EGZ89_RS00885	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EGZ89_RS00890	COG0456	acetyltransferase
EGZ89_RS00895	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EGZ89_RS00900	COG2244	polysaccharide biosynthetic process
EGZ89_RS00905	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EGZ89_RS00915	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EGZ89_RS00955	COG3071	HemY protein
EGZ89_RS00960	COG2959	enzyme of heme biosynthesis
EGZ89_RS00965	COG1587	Uroporphyrinogen-III synthase
EGZ89_RS00970	COG0181	hydroxymethylbilane synthase activity
EGZ89_RS00975	COG3072	Adenylate cyclase
EGZ89_RS00985	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EGZ89_RS00990	COG3159	Protein conserved in bacteria
EGZ89_RS01000	COG1011	Hydrolase
EGZ89_RS01005	COG0210	DNA helicase
EGZ89_RS01010	COG0598	Magnesium transport protein CorA
EGZ89_RS01015	COG2050	protein possibly involved in aromatic compounds catabolism
EGZ89_RS01020	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
EGZ89_RS01025	COG0514	ATP-dependent DNA helicase (RecQ)
EGZ89_RS01030	COG1280	lysine exporter protein (LysE YggA)
EGZ89_RS01035	COG2267	carboxylic ester hydrolase activity
EGZ89_RS01040	COG0561	phosphatase activity
EGZ89_RS01045	COG2271	Major facilitator Superfamily
EGZ89_RS01050	COG4807	Protein conserved in bacteria
EGZ89_RS01055	COG0583	DNA-binding transcription factor activity
EGZ89_RS01060	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EGZ89_RS01065	COG0412	Dienelactone hydrolase
EGZ89_RS01075	COG1322	Protein conserved in bacteria
EGZ89_RS01080	COG2226	methyltransferase
EGZ89_RS01090	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EGZ89_RS01100	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EGZ89_RS01105	COG0805	protein transport
EGZ89_RS01120	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EGZ89_RS01130	COG0183	Belongs to the thiolase family
EGZ89_RS01140	COG0006	proline dipeptidase activity
EGZ89_RS01145	COG1739	Uncharacterized protein family UPF0029
EGZ89_RS01150	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EGZ89_RS01155	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
EGZ89_RS01185	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EGZ89_RS01185	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EGZ89_RS01190	COG1072	(Pantothenic acid kinase))
EGZ89_RS01225	COG0250	Participates in transcription elongation, termination and antitermination
EGZ89_RS01230	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EGZ89_RS01235	COG0081	regulation of translation
EGZ89_RS01240	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EGZ89_RS01245	COG0222	ribosome binding
EGZ89_RS01250	COG0085	RNA polymerase activity
EGZ89_RS01255	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EGZ89_RS01300	COG4571	Outer membrane protease
EGZ89_RS01310	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EGZ89_RS01315	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
EGZ89_RS01320	COG2816	NAD+ diphosphatase activity
EGZ89_RS01325	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EGZ89_RS01330	COG1515	deoxyribonuclease V activity
EGZ89_RS01350	COG0151	Belongs to the GarS family
EGZ89_RS01355	COG0138	bifunctional purine biosynthesis protein purh
EGZ89_RS01380	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EGZ89_RS01385	COG1283	sodium-dependent phosphate transmembrane transporter activity
EGZ89_RS01390	COG0527	aspartate kinase activity
EGZ89_RS01395	COG0166	Belongs to the GPI family
EGZ89_RS01415	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EGZ89_RS01420	COG3223	Belongs to the PsiE family
EGZ89_RS01425	COG3161	chorismate lyase activity
EGZ89_RS01440	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EGZ89_RS01445	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EGZ89_RS01450	COG0534	Mate efflux family protein
EGZ89_RS01455	COG3237	CsbD-like
EGZ89_RS01460	COG0735	belongs to the Fur family
EGZ89_RS01480	COG1403	HNH endonuclease
EGZ89_RS01545	COG2246	polysaccharide biosynthetic process
EGZ89_RS01560	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EGZ89_RS01585	COG1448	Aminotransferase
EGZ89_RS01595	COG2315	Protein conserved in bacteria
EGZ89_RS01600	COG1470	cell adhesion involved in biofilm formation
EGZ89_RS01600	COG1388	LysM domain
EGZ89_RS01605	COG1064	alcohol dehydrogenase
EGZ89_RS01610	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EGZ89_RS01615	COG0629	single-stranded DNA binding
EGZ89_RS01620	COG2831	hemolysin activation secretion protein
EGZ89_RS01650	COG0625	glutathione transferase activity
EGZ89_RS01655	COG2252	PERMEase
EGZ89_RS01660	COG0025	NhaP-type Na H and K H
EGZ89_RS01665	COG0583	DNA-binding transcription factor activity
EGZ89_RS01670	COG1380	Effector of murein hydrolase LrgA
EGZ89_RS01675	COG1346	cytolysis
EGZ89_RS01685	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EGZ89_RS01690	COG3162	membrane
EGZ89_RS01700	COG1301	dicarboxylic acid transport
EGZ89_RS01705	COG0840	transmembrane signaling receptor activity
EGZ89_RS01725	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
EGZ89_RS01730	COG5001	Diguanylate cyclase
EGZ89_RS01730	COG3300	MHYT domain
EGZ89_RS01750	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EGZ89_RS01765	COG0583	DNA-binding transcription factor activity
EGZ89_RS01780	COG0583	DNA-binding transcription factor activity
EGZ89_RS01785	COG1280	lysine exporter protein (LysE YggA)
EGZ89_RS01795	COG2382	esterase
EGZ89_RS01800	COG5383	Protein conserved in bacteria
EGZ89_RS01805	COG0561	phosphatase activity
EGZ89_RS01815	COG1902	pentaerythritol trinitrate reductase activity
EGZ89_RS01825	COG1028	Short-chain dehydrogenase reductase Sdr
EGZ89_RS01835	COG4774	siderophore transport
EGZ89_RS01845	COG3486	L-lysine 6-monooxygenase (NADPH) activity
EGZ89_RS01850	COG0076	glutamate decarboxylase activity
EGZ89_RS02025	COG1181	Belongs to the D-alanine--D-alanine ligase family
EGZ89_RS02035	COG2890	protein-(glutamine-N5) methyltransferase activity
EGZ89_RS02050	COG0124	histidyl-tRNA synthetase
EGZ89_RS02065	COG0367	asparagine synthase
EGZ89_RS02075	COG2211	Major facilitator Superfamily
EGZ89_RS02090	COG1309	transcriptional regulator
EGZ89_RS02100	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EGZ89_RS02105	COG1027	Aspartate ammonia-lyase
EGZ89_RS02110	COG3030	protein affecting phage T7 exclusion by the F plasmid
EGZ89_RS02115	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EGZ89_RS02120	COG0459	protein refolding
EGZ89_RS02130	COG1509	lysine 2,3-aminomutase activity
EGZ89_RS02135	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EGZ89_RS02150	COG3040	lipid binding
EGZ89_RS02155	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EGZ89_RS02160	COG3264	Mechanosensitive ion channel
EGZ89_RS02160	COG1511	domain protein
EGZ89_RS02165	COG0688	phosphatidylethanolamine metabolic process
EGZ89_RS02170	COG1162	GTPase activity
EGZ89_RS02175	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EGZ89_RS02195	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EGZ89_RS02195	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EGZ89_RS02200	COG0802	atpase or kinase
EGZ89_RS02205	COG0860	N-Acetylmuramoyl-L-alanine amidase
EGZ89_RS02210	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EGZ89_RS02215	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EGZ89_RS02225	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EGZ89_RS02230	COG0330	HflC and HflK could
EGZ89_RS02235	COG0330	HflC and HflK could
EGZ89_RS02240	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
EGZ89_RS02245	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EGZ89_RS02250	COG0557	exoribonuclease II activity
EGZ89_RS02255	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EGZ89_RS02265	COG0840	transmembrane signaling receptor activity
EGZ89_RS02270	COG1073	alpha beta
EGZ89_RS02275	COG0360	Binds together with S18 to 16S ribosomal RNA
EGZ89_RS02280	COG2965	DNA replication, synthesis of RNA primer
EGZ89_RS02285	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EGZ89_RS02290	COG0359	binds to the 23S rRNA
EGZ89_RS02295	COG3061	Opacity-associated protein A
EGZ89_RS02300	COG0545	Peptidyl-prolyl cis-trans isomerase
EGZ89_RS02310	COG1218	3'(2'),5'-bisphosphate nucleotidase
EGZ89_RS02320	COG1253	flavin adenine dinucleotide binding
EGZ89_RS02325	COG0729	surface antigen
EGZ89_RS02335	COG2105	PFAM AIG2 family protein
EGZ89_RS02345	COG0840	transmembrane signaling receptor activity
EGZ89_RS02350	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EGZ89_RS02355	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EGZ89_RS02360	COG3028	Belongs to the UPF0307 family
EGZ89_RS02365	COG0312	modulator of DNA gyrase
EGZ89_RS02400	COG3964	amidohydrolase
EGZ89_RS02415	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGZ89_RS02415	COG3711	transcriptional antiterminator
EGZ89_RS02420	COG2823	Periplasmic or secreted lipoprotein
EGZ89_RS02425	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EGZ89_RS02430	COG0792	nuclease activity
EGZ89_RS02435	COG3107	peptidoglycan biosynthetic process
EGZ89_RS02440	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EGZ89_RS02465	COG1741	Belongs to the pirin family
EGZ89_RS02470	COG0583	DNA-binding transcription factor activity
EGZ89_RS02480	COG2259	Doxx family
EGZ89_RS02490	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
EGZ89_RS02495	COG4575	ribosome binding
EGZ89_RS02500	COG1422	Protein of unknown function (DUF1090)
EGZ89_RS02510	COG0586	Pfam SNARE associated Golgi protein
EGZ89_RS02520	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
EGZ89_RS02525	COG0861	Integral membrane protein TerC family
EGZ89_RS02530	COG0038	chloride channel
EGZ89_RS02535	COG1063	alcohol dehydrogenase
EGZ89_RS02540	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EGZ89_RS02545	COG2223	nitrite transmembrane transporter activity
EGZ89_RS02550	COG1451	nucleotide metabolic process
EGZ89_RS02555	COG2813	Specifically methylates the guanine in position
EGZ89_RS02560	COG1902	pentaerythritol trinitrate reductase activity
EGZ89_RS02560	COG0446	pyridine nucleotide-disulphide oxidoreductase
EGZ89_RS02570	COG0288	reversible hydration of carbon dioxide
EGZ89_RS02575	COG0659	secondary active sulfate transmembrane transporter activity
EGZ89_RS02590	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EGZ89_RS02595	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
EGZ89_RS02605	COG0535	radical SAM domain protein
EGZ89_RS02630	COG3731	PTS system glucitol sorbitol-specific IIA component
EGZ89_RS02635	COG1028	Short-chain dehydrogenase reductase Sdr
EGZ89_RS02640	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGZ89_RS02645	COG1349	DNA-binding transcription factor activity
EGZ89_RS02650	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EGZ89_RS02650	COG0517	IMP dehydrogenase activity
EGZ89_RS02740	COG0477	Major facilitator Superfamily
EGZ89_RS02745	COG1609	Transcriptional regulator
EGZ89_RS02770	COG3706	GGDEF domain
EGZ89_RS02795	COG2813	Specifically methylates the guanine in position
EGZ89_RS02800	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
EGZ89_RS02805	COG0456	acetyltransferase
EGZ89_RS02810	COG1011	Hydrolase
EGZ89_RS02930	COG3501	Rhs element vgr protein
EGZ89_RS02950	COG3501	Rhs element vgr protein
EGZ89_RS02960	COG3209	COG3209 Rhs family protein
EGZ89_RS02995	COG1397	ADP-ribosylglycohydrolase
EGZ89_RS03000	COG2818	Glycosylase
EGZ89_RS03005	COG2755	lipolytic protein G-D-S-L family
EGZ89_RS03005	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EGZ89_RS03010	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EGZ89_RS03015	COG2823	Periplasmic or secreted lipoprotein
EGZ89_RS03020	COG5487	UPF0391 membrane protein
EGZ89_RS03025	COG4667	esterase of the alpha-beta hydrolase superfamily
EGZ89_RS03030	COG0084	hydrolase, TatD family'
EGZ89_RS03035	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EGZ89_RS03040	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EGZ89_RS03045	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EGZ89_RS03050	COG0813	purine-nucleoside phosphorylase activity
EGZ89_RS03055	COG3550	peptidyl-serine autophosphorylation
EGZ89_RS03060	COG3726	membrane protein affecting hemolysin expression
EGZ89_RS03065	COG0560	Phosphoserine phosphatase
EGZ89_RS03090	COG0604	alcohol dehydrogenase
EGZ89_RS03095	COG0583	DNA-binding transcription factor activity
EGZ89_RS03100	COG0488	(ABC) transporter
EGZ89_RS03110	COG1349	DNA-binding transcription factor activity
EGZ89_RS03120	COG0741	lytic transglycosylase activity
EGZ89_RS03125	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
EGZ89_RS03130	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
EGZ89_RS03135	COG0406	alpha-ribazole phosphatase activity
EGZ89_RS03145	COG2207	Transcriptional regulator
EGZ89_RS03145	COG3708	Transcriptional regulator
EGZ89_RS03150	COG3045	CreA protein
EGZ89_RS03155	COG0745	RESPONSE REGULATOR receiver
EGZ89_RS03170	COG0083	homoserine kinase activity
EGZ89_RS03180	COG3022	response to hydroperoxide
EGZ89_RS03190	COG0521	Mo-molybdopterin cofactor biosynthetic process
EGZ89_RS03200	COG0443	Heat shock 70 kDa protein
EGZ89_RS03205	COG0484	heat shock protein binding
EGZ89_RS03210	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EGZ89_RS03215	COG0268	Binds directly to 16S ribosomal RNA
EGZ89_RS03220	COG0196	riboflavin kinase activity
EGZ89_RS03225	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EGZ89_RS03230	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EGZ89_RS03235	COG1047	Peptidyl-prolyl cis-trans
EGZ89_RS03240	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EGZ89_RS03245	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EGZ89_RS03250	COG0505	Belongs to the CarA family
EGZ89_RS03260	COG1280	lysine exporter protein (LysE YggA)
EGZ89_RS03265	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EGZ89_RS03270	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EGZ89_RS03275	COG2967	ApaG domain
EGZ89_RS03280	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EGZ89_RS03285	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EGZ89_RS03300	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EGZ89_RS03305	COG0564	pseudouridine synthase activity
EGZ89_RS03310	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EGZ89_RS03315	COG0417	DNA replication proofreading
EGZ89_RS03320	COG0586	Pfam SNARE associated Golgi protein
EGZ89_RS03325	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
EGZ89_RS03330	COG1178	ABC-type Fe3 transport system permease component
EGZ89_RS03335	COG4143	(ABC) transporter
EGZ89_RS03340	COG4533	DNA binding
EGZ89_RS03345	COG2814	Major facilitator Superfamily
EGZ89_RS03350	COG0066	3-isopropylmalate dehydratase activity
EGZ89_RS03360	COG0473	3-isopropylmalate dehydrogenase activity
EGZ89_RS03365	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EGZ89_RS03375	COG0028	Belongs to the TPP enzyme family
EGZ89_RS03390	COG2001	Belongs to the MraZ family
EGZ89_RS03395	COG0275	rRNA processing
EGZ89_RS03400	COG3116	cell division
EGZ89_RS03405	COG0768	penicillin binding
EGZ89_RS03410	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EGZ89_RS03415	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EGZ89_RS03420	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EGZ89_RS03430	COG0772	Belongs to the SEDS family
EGZ89_RS03435	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EGZ89_RS03445	COG1181	Belongs to the D-alanine--D-alanine ligase family
EGZ89_RS03455	COG0849	cell division
EGZ89_RS03460	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EGZ89_RS03465	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EGZ89_RS03480	COG0653	protein targeting
EGZ89_RS03490	COG3397	chitin binding
EGZ89_RS03565	COG0494	nUDIX hydrolase
EGZ89_RS03570	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
EGZ89_RS03575	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
EGZ89_RS03585	COG0516	GMP reductase activity
EGZ89_RS03590	COG1459	type II secretion system
EGZ89_RS03595	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EGZ89_RS03600	COG4969	Belongs to the N-Me-Phe pilin family
EGZ89_RS03615	COG3725	Membrane protein required for beta-lactamase induction
EGZ89_RS03640	COG3940	Belongs to the glycosyl hydrolase 43 family
EGZ89_RS03645	COG2211	Major facilitator Superfamily
EGZ89_RS03650	COG1113	amino acid transport
EGZ89_RS03655	COG2186	Transcriptional regulator
EGZ89_RS03660	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EGZ89_RS03665	COG0508	dehydrogenase complex catalyzes the overall conversion of
EGZ89_RS03670	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGZ89_RS03675	COG1028	Short-chain dehydrogenase reductase Sdr
EGZ89_RS03680	COG1122	ATPase activity
EGZ89_RS03685	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EGZ89_RS03690	COG1268	BioY protein
EGZ89_RS03705	COG0318	PFAM AMP-dependent synthetase and ligase
EGZ89_RS03710	COG0183	Belongs to the thiolase family
EGZ89_RS03715	COG1024	Enoyl-CoA hydratase
EGZ89_RS03720	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EGZ89_RS03730	COG2175	clavaminate synthase activity
EGZ89_RS03735	COG1203	CRISPR-associated helicase, Cas3
EGZ89_RS03750	COG1857	crispr-associated protein
EGZ89_RS03765	COG1518	maintenance of DNA repeat elements
EGZ89_RS03770	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EGZ89_RS03790	COG3112	Uncharacterised protein family (UPF0231)
EGZ89_RS03795	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EGZ89_RS03800	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EGZ89_RS03830	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EGZ89_RS03835	COG0288	reversible hydration of carbon dioxide
EGZ89_RS03840	COG1131	(ABC) transporter
EGZ89_RS03845	COG0842	Transport permease protein
EGZ89_RS03850	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EGZ89_RS03855	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EGZ89_RS03860	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EGZ89_RS03865	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EGZ89_RS03885	COG1489	DNA binding
EGZ89_RS03890	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EGZ89_RS03895	COG1643	Atp-dependent helicase
EGZ89_RS03900	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EGZ89_RS03910	COG3209	COG3209 Rhs family protein
EGZ89_RS03910	COG4104	PAAR repeat-containing protein
EGZ89_RS03925	COG3077	Addiction module antitoxin, RelB DinJ family
EGZ89_RS03930	COG2026	Addiction module toxin, RelE StbE family
EGZ89_RS03945	COG1120	ATPase activity
EGZ89_RS03950	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EGZ89_RS03960	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EGZ89_RS03965	COG0316	Belongs to the HesB IscA family
EGZ89_RS03975	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EGZ89_RS03985	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EGZ89_RS03995	COG2171	N-acyltransferase activity
EGZ89_RS04000	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EGZ89_RS04010	COG0052	Belongs to the universal ribosomal protein uS2 family
EGZ89_RS04015	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EGZ89_RS04020	COG0528	UMP kinase activity
EGZ89_RS04025	COG0233	cytoplasmic translational termination
EGZ89_RS04030	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EGZ89_RS04035	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EGZ89_RS04040	COG0575	Belongs to the CDS family
EGZ89_RS04045	COG0750	zinc metalloprotease
EGZ89_RS04050	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EGZ89_RS04055	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
EGZ89_RS04060	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EGZ89_RS04065	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EGZ89_RS04070	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EGZ89_RS04075	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EGZ89_RS04080	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EGZ89_RS04090	COG0825	malonyl-CoA metabolic process
EGZ89_RS04100	COG0346	lactoylglutathione lyase activity
EGZ89_RS04105	COG0037	tRNA processing
EGZ89_RS04115	COG4568	rho-dependent transcription termination
EGZ89_RS04140	COG0442	prolyl-tRNA aminoacylation
EGZ89_RS04145	COG1720	tRNA m6t6A37 methyltransferase activity
EGZ89_RS04155	COG1464	Belongs to the NlpA lipoprotein family
EGZ89_RS04160	COG2011	ABC-type metal ion transport system permease component
EGZ89_RS04165	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EGZ89_RS04170	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EGZ89_RS04200	COG0477	Major facilitator Superfamily
EGZ89_RS04205	COG5544	Lipoprotein
EGZ89_RS04210	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EGZ89_RS04215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EGZ89_RS04215	COG1042	CoA-binding domain protein
EGZ89_RS04215	COG0045	succinate-CoA ligase (ADP-forming) activity
EGZ89_RS04225	COG3118	belongs to the thioredoxin family
EGZ89_RS04230	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EGZ89_RS04235	COG2814	Major facilitator Superfamily
EGZ89_RS04240	COG1566	PFAM secretion protein HlyD family protein
EGZ89_RS04245	COG1846	Transcriptional regulator
EGZ89_RS04250	COG2814	Major facilitator Superfamily
EGZ89_RS04255	COG2113	Glycine betaine
EGZ89_RS04260	COG4176	ABC-type proline glycine betaine transport system permease component
EGZ89_RS04280	COG1780	Probably involved in ribonucleotide reductase function
EGZ89_RS04285	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EGZ89_RS04300	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EGZ89_RS04315	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EGZ89_RS04330	COG0745	RESPONSE REGULATOR receiver
EGZ89_RS04340	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EGZ89_RS04345	COG1677	Flagellar hook-basal body complex protein FliE
EGZ89_RS04360	COG1317	bacterial-type flagellum organization
EGZ89_RS04365	COG1157	protein secretion by the type III secretion system
EGZ89_RS04380	COG1580	Controls the rotational direction of flagella during chemotaxis
EGZ89_RS04390	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EGZ89_RS04395	COG3190	flagellar
EGZ89_RS04405	COG1987	bacterial-type flagellum assembly
EGZ89_RS04415	COG4797	methyltransferase
EGZ89_RS04415	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EGZ89_RS04460	COG3418	PFAM FlgN family protein
EGZ89_RS04475	COG1815	bacterial-type flagellum-dependent cell motility
EGZ89_RS04505	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EGZ89_RS04515	COG3951	Flagellar rod assembly protein muramidase FlgJ
EGZ89_RS04515	COG1705	Flagellar rod assembly protein muramidase FlgJ
EGZ89_RS04525	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EGZ89_RS04530	COG0840	transmembrane signaling receptor activity
EGZ89_RS04560	COG2198	Histidine kinase
EGZ89_RS04560	COG0643	Histidine kinase
EGZ89_RS04565	COG0835	chemotaxis
EGZ89_RS04590	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EGZ89_RS04595	COG2867	negative regulation of translational initiation
EGZ89_RS04600	COG2914	Belongs to the UPF0125 (RnfH) family
EGZ89_RS04605	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EGZ89_RS04610	COG0497	DNA recombination
EGZ89_RS04615	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EGZ89_RS04620	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EGZ89_RS04625	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EGZ89_RS04630	COG0513	Belongs to the DEAD box helicase family
EGZ89_RS04635	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EGZ89_RS04640	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EGZ89_RS04645	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EGZ89_RS04660	COG3026	antisigma factor binding
EGZ89_RS04665	COG3086	response to oxidative stress
EGZ89_RS04680	COG0481	GTPase activity
EGZ89_RS04690	COG0571	ribonuclease III activity
EGZ89_RS04700	COG1381	Involved in DNA repair and RecF pathway recombination
EGZ89_RS04705	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EGZ89_RS04710	COG0736	holo-[acyl-carrier-protein] synthase activity
EGZ89_RS04720	COG1737	Transcriptional regulator
EGZ89_RS04725	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EGZ89_RS04730	COG0560	Phosphoserine phosphatase
EGZ89_RS04740	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
EGZ89_RS04745	COG0047	phosphoribosylformylglycinamidine synthase activity
EGZ89_RS04745	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EGZ89_RS04750	COG2205	protein histidine kinase activity
EGZ89_RS04755	COG3170	Tfp pilus assembly protein FimV
EGZ89_RS04760	COG2204	response regulator
EGZ89_RS04765	COG0347	Belongs to the P(II) protein family
EGZ89_RS04770	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EGZ89_RS04775	COG3711	transcriptional antiterminator
EGZ89_RS04780	COG0483	inositol monophosphate 1-phosphatase activity
EGZ89_RS04790	COG1959	2 iron, 2 sulfur cluster binding
EGZ89_RS04795	COG1104	cysteine desulfurase activity
EGZ89_RS04800	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EGZ89_RS04810	COG0531	amino acid
EGZ89_RS04815	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EGZ89_RS04825	COG3938	Belongs to the proline racemase family
EGZ89_RS04840	COG0446	pyridine nucleotide-disulphide oxidoreductase
EGZ89_RS04845	COG1012	belongs to the aldehyde dehydrogenase family
EGZ89_RS04855	COG2897	thiosulfate sulfurtransferase activity
EGZ89_RS04860	COG0105	UTP biosynthetic process
EGZ89_RS04865	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EGZ89_RS04875	COG1426	Protein conserved in bacteria
EGZ89_RS04880	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EGZ89_RS04885	COG0124	histidyl-tRNA synthetase
EGZ89_RS04890	COG2976	Protein conserved in bacteria
EGZ89_RS04895	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EGZ89_RS04900	COG1160	GTP binding
EGZ89_RS04910	COG4993	Dehydrogenase
EGZ89_RS04925	COG1570	exodeoxyribonuclease VII activity
EGZ89_RS04930	COG0517	IMP dehydrogenase activity
EGZ89_RS04930	COG0516	GMP reductase activity
EGZ89_RS04965	COG3122	Protein conserved in bacteria
EGZ89_RS04980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGZ89_RS04985	COG2271	Major facilitator Superfamily
EGZ89_RS04990	COG2239	Acts as a magnesium transporter
EGZ89_RS04995	COG2200	EAL domain
EGZ89_RS05000	COG0500	methyltransferase
EGZ89_RS05010	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EGZ89_RS05015	COG0573	inorganic phosphate transmembrane transporter activity
EGZ89_RS05020	COG0581	inorganic phosphate transmembrane transporter activity
EGZ89_RS05025	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EGZ89_RS05030	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EGZ89_RS05035	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EGZ89_RS05045	COG2233	PERMEase
EGZ89_RS05050	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EGZ89_RS05055	COG1393	Belongs to the ArsC family
EGZ89_RS05065	COG3706	GGDEF domain
EGZ89_RS05070	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EGZ89_RS05075	COG2716	regulation of RNA biosynthetic process
EGZ89_RS05080	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EGZ89_RS05085	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
EGZ89_RS05090	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EGZ89_RS05095	COG2321	neutral zinc metallopeptidase
EGZ89_RS05100	COG1444	tRNA N-acetyltransferase activity
EGZ89_RS05115	COG4104	PAAR repeat-containing protein
EGZ89_RS05115	COG3209	COG3209 Rhs family protein
EGZ89_RS05135	COG4104	PAAR repeat-containing protein
EGZ89_RS05135	COG3209	COG3209 Rhs family protein
EGZ89_RS05160	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EGZ89_RS05165	COG1393	Belongs to the ArsC family
EGZ89_RS05180	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGZ89_RS05185	COG2197	response regulator
EGZ89_RS05190	COG3850	Histidine kinase
EGZ89_RS05205	COG0494	nUDIX hydrolase
EGZ89_RS05210	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EGZ89_RS05215	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EGZ89_RS05220	COG0408	coproporphyrinogen oxidase activity
EGZ89_RS05225	COG0860	N-Acetylmuramoyl-L-alanine amidase
EGZ89_RS05250	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EGZ89_RS05255	COG4208	sulfate ABC transporter
EGZ89_RS05260	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EGZ89_RS05270	COG0745	RESPONSE REGULATOR receiver
EGZ89_RS05275	COG2205	protein histidine kinase activity
EGZ89_RS05285	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EGZ89_RS05295	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EGZ89_RS05300	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
EGZ89_RS05305	COG3115	cell septum assembly
EGZ89_RS05310	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EGZ89_RS05315	COG3530	Putative quorum-sensing-regulated virulence factor
EGZ89_RS05320	COG0385	Bile acid
EGZ89_RS05325	COG0583	DNA-binding transcription factor activity
EGZ89_RS05370	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EGZ89_RS05375	COG3415	Transposase
EGZ89_RS05380	COG2116	formate transmembrane transporter activity
EGZ89_RS05395	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EGZ89_RS05400	COG1914	H( )-stimulated, divalent metal cation uptake system
EGZ89_RS05410	COG0667	Aldo Keto reductase
EGZ89_RS05415	COG3961	Belongs to the TPP enzyme family
EGZ89_RS05420	COG0837	glucose binding
EGZ89_RS05435	COG0436	Aminotransferase
EGZ89_RS05475	COG0668	transmembrane transport
EGZ89_RS05510	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EGZ89_RS05515	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EGZ89_RS05520	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EGZ89_RS05525	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
EGZ89_RS05530	COG1138	Cytochrome C-type biogenesis protein
EGZ89_RS05540	COG4235	cytochrome complex assembly
EGZ89_RS05540	COG3088	subunit of a heme lyase
EGZ89_RS05545	COG3088	subunit of a heme lyase
EGZ89_RS05545	COG4235	cytochrome complex assembly
EGZ89_RS05555	COG2067	long-chain fatty acid transport protein
EGZ89_RS05570	COG0183	Belongs to the thiolase family
EGZ89_RS05575	COG1250	3-hydroxyacyl-CoA dehydrogenase
EGZ89_RS05575	COG1024	Enoyl-CoA hydratase
EGZ89_RS05580	COG2062	phosphohistidine phosphatase, SixA
EGZ89_RS05585	COG2840	Smr protein MutS2
EGZ89_RS05595	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EGZ89_RS05605	COG0730	response to heat
EGZ89_RS05610	COG3101	peptidyl-lysine hydroxylation
EGZ89_RS05625	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EGZ89_RS05670	COG2207	Transcriptional regulator
EGZ89_RS05680	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EGZ89_RS05690	COG0586	Pfam SNARE associated Golgi protein
EGZ89_RS05705	COG0285	dihydrofolate synthase activity
EGZ89_RS05710	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
EGZ89_RS05715	COG1286	toxin biosynthetic process
EGZ89_RS05720	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EGZ89_RS05725	COG0163	prenyltransferase activity
EGZ89_RS05740	COG4160	amino acid transport
EGZ89_RS05745	COG4598	ABC transporter
EGZ89_RS05750	COG1090	epimerase
EGZ89_RS05765	COG1177	transmembrane transport
EGZ89_RS05770	COG1176	ABC-type spermidine putrescine transport system, permease component I
EGZ89_RS05780	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EGZ89_RS05790	COG3842	ATPase activity
EGZ89_RS05795	COG0280	phosphate acetyltransferase
EGZ89_RS05795	COG0857	belongs to the CobB CobQ family
EGZ89_RS05800	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EGZ89_RS05805	COG3092	negative regulation of chromosome organization
EGZ89_RS05810	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EGZ89_RS05830	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
EGZ89_RS05835	COG0436	Aminotransferase
EGZ89_RS05840	COG0583	DNA-binding transcription factor activity
EGZ89_RS05845	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EGZ89_RS05850	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EGZ89_RS05855	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EGZ89_RS05855	COG0649	NAD binding
EGZ89_RS05865	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EGZ89_RS05875	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EGZ89_RS05880	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EGZ89_RS05885	COG0839	Belongs to the complex I subunit 6 family
EGZ89_RS05890	COG0713	ATP synthesis coupled electron transport
EGZ89_RS05895	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EGZ89_RS05900	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EGZ89_RS05905	COG1007	ATP synthesis coupled electron transport
EGZ89_RS05920	COG2153	protein acetylation
EGZ89_RS05925	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
EGZ89_RS05930	COG4575	ribosome binding
EGZ89_RS05945	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
EGZ89_RS05965	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EGZ89_RS05975	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EGZ89_RS05980	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EGZ89_RS05990	COG0784	Response regulator, receiver
EGZ89_RS05990	COG2205	protein histidine kinase activity
EGZ89_RS05995	COG2197	response regulator
EGZ89_RS06000	COG2198	Histidine kinase
EGZ89_RS06000	COG0642	Histidine kinase
EGZ89_RS06025	COG3145	DNA-N1-methyladenine dioxygenase activity
EGZ89_RS06035	COG2977	Belongs to the P-Pant transferase superfamily
EGZ89_RS06095	COG3083	sulfuric ester hydrolase activity
EGZ89_RS06100	COG3082	Protein of unknown function (DUF1414)
EGZ89_RS06105	COG3081	Nucleoid-associated protein
EGZ89_RS06110	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EGZ89_RS06115	COG1061	Type III restriction enzyme res subunit
EGZ89_RS06120	COG1187	pseudouridine synthase activity
EGZ89_RS06125	COG2814	Major facilitator Superfamily
EGZ89_RS06135	COG4172	Belongs to the ABC transporter superfamily
EGZ89_RS06140	COG4239	(ABC) transporter, permease
EGZ89_RS06145	COG4174	ABC transporter (Permease)
EGZ89_RS06150	COG4166	transmembrane transport
EGZ89_RS06155	COG2200	EAL domain
EGZ89_RS06160	COG0791	NLP P60 protein
EGZ89_RS06165	COG0671	phosphoesterase, PA-phosphatase related
EGZ89_RS06170	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EGZ89_RS06180	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGZ89_RS06180	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGZ89_RS06185	COG1105	Belongs to the carbohydrate kinase PfkB family
EGZ89_RS06190	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EGZ89_RS06190	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGZ89_RS06190	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGZ89_RS06195	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EGZ89_RS06200	COG2855	membrane
EGZ89_RS06205	COG0583	DNA-binding transcription factor activity
EGZ89_RS06210	COG0833	amino acid
EGZ89_RS06215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGZ89_RS06220	COG1120	ATPase activity
EGZ89_RS06240	COG0583	DNA-binding transcription factor activity
EGZ89_RS06245	COG0302	gtp cyclohydrolase
EGZ89_RS06250	COG2311	Membrane
EGZ89_RS06255	COG1609	Transcriptional regulator
EGZ89_RS06265	COG1129	ABC transporter
EGZ89_RS06275	COG2949	membrane
EGZ89_RS06280	COG0281	malic enzyme
EGZ89_RS06285	COG0295	cytidine deaminase activity
EGZ89_RS06290	COG1346	cytolysis
EGZ89_RS06295	COG1380	Effector of murein hydrolase LrgA
EGZ89_RS06300	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EGZ89_RS06300	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EGZ89_RS06305	COG0489	protein tyrosine kinase activity
EGZ89_RS06320	COG1605	Chorismate mutase
EGZ89_RS06330	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EGZ89_RS06335	COG0351	phosphomethylpyrimidine kinase
EGZ89_RS06340	COG1597	lipid kinase activity
EGZ89_RS06360	COG0745	RESPONSE REGULATOR receiver
EGZ89_RS06365	COG2205	protein histidine kinase activity
EGZ89_RS06390	COG0443	Heat shock 70 kDa protein
EGZ89_RS06395	COG5002	protein histidine kinase activity
EGZ89_RS06395	COG5001	Diguanylate cyclase
EGZ89_RS06395	COG3447	MASE1 domain protein
EGZ89_RS06405	COG0572	uridine kinase
EGZ89_RS06410	COG0717	Belongs to the dCTP deaminase family
EGZ89_RS06415	COG2982	Protein involved in outer membrane biogenesis
EGZ89_RS06420	COG1253	flavin adenine dinucleotide binding
EGZ89_RS06485	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EGZ89_RS06520	COG1442	glycosyl transferase family 8
EGZ89_RS06550	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EGZ89_RS06555	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EGZ89_RS06555	COG0140	phosphoribosyl-ATP diphosphatase activity
EGZ89_RS06565	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EGZ89_RS06570	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EGZ89_RS06575	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EGZ89_RS06575	COG0131	Imidazoleglycerol-phosphate dehydratase
EGZ89_RS06580	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EGZ89_RS06590	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EGZ89_RS06600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGZ89_RS06605	COG0531	amino acid
EGZ89_RS06610	COG2925	Exonuclease
EGZ89_RS06620	COG1289	transmembrane transporter activity
EGZ89_RS06625	COG2926	Belongs to the UPF0265 family
EGZ89_RS06630	COG0534	Mate efflux family protein
EGZ89_RS06640	COG0596	Alpha beta hydrolase
EGZ89_RS06645	COG1280	lysine exporter protein (LysE YggA)
EGZ89_RS06660	COG0077	Prephenate dehydratase
EGZ89_RS06665	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EGZ89_RS06685	COG1522	sequence-specific DNA binding
EGZ89_RS06695	COG3284	Transcriptional regulator
EGZ89_RS06700	COG1063	alcohol dehydrogenase
EGZ89_RS06705	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EGZ89_RS06745	COG0583	DNA-binding transcription factor activity
EGZ89_RS06750	COG1280	lysine exporter protein (LysE YggA)
EGZ89_RS06795	COG0747	negative chemotaxis
EGZ89_RS06800	COG0601	transmembrane transport
EGZ89_RS06805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EGZ89_RS06810	COG4172	Belongs to the ABC transporter superfamily
EGZ89_RS06820	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGZ89_RS06850	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EGZ89_RS06855	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EGZ89_RS06860	COG1121	(ABC) transporter
EGZ89_RS06865	COG0803	Belongs to the bacterial solute-binding protein 9 family
EGZ89_RS06870	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EGZ89_RS06880	COG3228	Belongs to the MtfA family
EGZ89_RS06890	COG1418	mRNA catabolic process
EGZ89_RS06895	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EGZ89_RS06905	COG3727	T/G mismatch-specific endonuclease activity
EGZ89_RS06915	COG2354	Protein conserved in bacteria
EGZ89_RS06920	COG5475	Uncharacterized small protein (DUF2158)
EGZ89_RS06935	COG0366	Alpha amylase catalytic
EGZ89_RS06945	COG1516	flagellar protein fliS
EGZ89_RS06950	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EGZ89_RS06955	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EGZ89_RS06955	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EGZ89_RS06980	COG4763	Acyl-transferase
EGZ89_RS06985	COG0506	proline dehydrogenase activity
EGZ89_RS06985	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EGZ89_RS06985	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EGZ89_RS07010	COG1702	phosphate starvation-inducible protein PhoH
EGZ89_RS07025	COG0778	Nitroreductase
EGZ89_RS07050	COG3381	protein complex oligomerization
EGZ89_RS07060	COG1012	belongs to the aldehyde dehydrogenase family
EGZ89_RS07065	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EGZ89_RS07070	COG1216	Glycosyl transferase, family 2
EGZ89_RS07075	COG2244	polysaccharide biosynthetic process
EGZ89_RS07085	COG0431	NADPH-dependent FMN reductase
EGZ89_RS07090	COG0113	porphobilinogen synthase activity
EGZ89_RS07145	COG0835	chemotaxis
EGZ89_RS07165	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EGZ89_RS07175	COG0745	RESPONSE REGULATOR receiver
EGZ89_RS07185	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EGZ89_RS07200	COG0018	arginyl-trna synthetase
EGZ89_RS07205	COG3102	Protein conserved in bacteria
EGZ89_RS07210	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EGZ89_RS07215	COG3142	Participates in the control of copper homeostasis
EGZ89_RS07225	COG0500	methyltransferase
EGZ89_RS07230	COG2226	methyltransferase
EGZ89_RS07235	COG3788	relative of glutathione S-transferase, MAPEG superfamily
EGZ89_RS07240	COG1801	Protein of unknown function DUF72
EGZ89_RS07245	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EGZ89_RS07250	COG0494	nUDIX hydrolase
EGZ89_RS07255	COG0217	transcriptional regulatory protein
EGZ89_RS07260	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EGZ89_RS07265	COG0632	four-way junction helicase activity
EGZ89_RS07270	COG2255	four-way junction helicase activity
EGZ89_RS07275	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EGZ89_RS07285	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
EGZ89_RS07290	COG0739	heme binding
EGZ89_RS07295	COG1560	Kdo2-lipid A biosynthetic process
EGZ89_RS07305	COG0469	pyruvate kinase activity
EGZ89_RS07310	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EGZ89_RS07315	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EGZ89_RS07320	COG3141	response to X-ray
EGZ89_RS07325	COG1082	Xylose isomerase domain protein TIM barrel
EGZ89_RS07330	COG1770	oligopeptidase
EGZ89_RS07335	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EGZ89_RS07380	COG0628	permease
EGZ89_RS07395	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EGZ89_RS07395	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
EGZ89_RS07400	COG3008	intermembrane lipid transfer
EGZ89_RS07405	COG2995	paraquat-inducible protein a
EGZ89_RS07410	COG1956	GAF domain-containing protein
EGZ89_RS07415	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
EGZ89_RS07425	COG0501	Belongs to the peptidase M48B family
EGZ89_RS07455	COG2226	methyltransferase
EGZ89_RS07460	COG1253	flavin adenine dinucleotide binding
EGZ89_RS07465	COG1760	l-serine dehydratase
EGZ89_RS07480	COG3140	Belongs to the UPF0181 family
EGZ89_RS07485	COG0251	oxidation-reduction process
EGZ89_RS07490	COG1199	ATP-dependent helicase activity
EGZ89_RS07500	COG3065	identical protein binding
EGZ89_RS07505	COG0318	PFAM AMP-dependent synthetase and ligase
EGZ89_RS07515	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EGZ89_RS07520	COG2894	cell division
EGZ89_RS07525	COG0850	regulation of cytokinetic process
EGZ89_RS07530	COG3100	YcgL domain-containing protein
EGZ89_RS07535	COG0179	Fumarylacetoacetate (FAA) hydrolase
EGZ89_RS07550	COG2186	Transcriptional regulator
EGZ89_RS07555	COG2719	SpoVR family
EGZ89_RS07560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EGZ89_RS07565	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EGZ89_RS07590	COG2718	Belongs to the UPF0229 family
EGZ89_RS07595	COG2766	serine protein kinase
EGZ89_RS07600	COG3713	MltA-interacting MipA family protein
EGZ89_RS07605	COG0656	L-ascorbic acid biosynthetic process
EGZ89_RS07620	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EGZ89_RS07625	COG3139	Protein of unknown function (DUF1315)
EGZ89_RS07630	COG1335	isochorismatase
EGZ89_RS07635	COG0252	asparaginase activity
EGZ89_RS07640	COG0616	signal peptide processing
EGZ89_RS07645	COG0778	Nitroreductase
EGZ89_RS07660	COG0708	Exodeoxyribonuclease III
EGZ89_RS07695	COG0788	formyltetrahydrofolate deformylase activity
EGZ89_RS07700	COG3012	SEC-C Motif Domain Protein
EGZ89_RS07705	COG0745	RESPONSE REGULATOR receiver
EGZ89_RS07710	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EGZ89_RS07760	COG2828	Protein conserved in bacteria
EGZ89_RS07765	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EGZ89_RS07770	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EGZ89_RS07775	COG0583	DNA-binding transcription factor activity
EGZ89_RS07780	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EGZ89_RS07790	COG3384	dioxygenase
EGZ89_RS07805	COG2095	MarC family integral membrane protein
EGZ89_RS07810	COG4166	transmembrane transport
EGZ89_RS07820	COG0601	transmembrane transport
EGZ89_RS07825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EGZ89_RS07830	COG0444	Belongs to the ABC transporter superfamily
EGZ89_RS07840	COG3099	Belongs to the UPF0263 family
EGZ89_RS07845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EGZ89_RS07860	COG2350	Protein conserved in bacteria
EGZ89_RS07875	COG2917	probably involved in intracellular septation
EGZ89_RS07885	COG3047	cAMP biosynthetic process
EGZ89_RS07895	COG0159	tryptophan synthase activity
EGZ89_RS07900	COG0133	tryptophan synthase activity
EGZ89_RS07910	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EGZ89_RS07915	COG0512	Glutamine amidotransferase of anthranilate synthase
EGZ89_RS07915	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EGZ89_RS07925	COG0613	PHP domain protein
EGZ89_RS07930	COG0009	L-threonylcarbamoyladenylate synthase
EGZ89_RS07940	COG1028	Short-chain dehydrogenase reductase Sdr
EGZ89_RS07945	COG0616	signal peptide processing
EGZ89_RS07970	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EGZ89_RS07980	COG0671	phosphoesterase, PA-phosphatase related
EGZ89_RS07985	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
EGZ89_RS07990	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EGZ89_RS07995	COG0284	orotidine-5'-phosphate decarboxylase activity
EGZ89_RS08000	COG0023	Translation Initiation Factor
EGZ89_RS08015	COG0235	Class ii aldolase
EGZ89_RS08020	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
EGZ89_RS08055	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EGZ89_RS08055	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EGZ89_RS08065	COG4172	Belongs to the ABC transporter superfamily
EGZ89_RS08070	COG4172	Belongs to the ABC transporter superfamily
EGZ89_RS08075	COG4171	peptide transport system, permease
EGZ89_RS08080	COG4168	peptide transport system, permease
EGZ89_RS08090	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EGZ89_RS08095	COG1842	Phage shock protein A
EGZ89_RS08105	COG1983	PspC domain protein
EGZ89_RS08115	COG3106	COG3106 Predicted ATPase
EGZ89_RS08120	COG3768	UPF0283 membrane protein
EGZ89_RS08135	COG4948	Mandelate Racemase Muconate Lactonizing
EGZ89_RS08140	COG4166	transmembrane transport
EGZ89_RS08160	COG3188	usher protein
EGZ89_RS08165	COG3121	Chaperone
EGZ89_RS08170	COG3539	Fimbrial protein
EGZ89_RS08180	COG0366	Alpha amylase catalytic
EGZ89_RS08185	COG0037	tRNA processing
EGZ89_RS08195	COG0513	Belongs to the DEAD box helicase family
EGZ89_RS08210	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EGZ89_RS08215	COG2911	Protein conserved in bacteria
EGZ89_RS08225	COG3784	Protein of unknown function (DUF1318)
EGZ89_RS08230	COG1028	Short-chain dehydrogenase reductase Sdr
EGZ89_RS08235	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EGZ89_RS08240	COG1643	Atp-dependent helicase
EGZ89_RS08245	COG3023	N-Acetylmuramoyl-L-alanine amidase
EGZ89_RS08250	COG3591	Belongs to the peptidase S1B family
EGZ89_RS08260	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EGZ89_RS08265	COG2205	protein histidine kinase activity
EGZ89_RS08270	COG0582	viral genome integration into host DNA
EGZ89_RS08310	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EGZ89_RS08325	COG0745	RESPONSE REGULATOR receiver
EGZ89_RS08335	COG0531	amino acid
EGZ89_RS08350	COG3182	Iron-regulated membrane protein
EGZ89_RS08375	COG2840	Smr protein MutS2
EGZ89_RS08395	COG2814	Major facilitator Superfamily
EGZ89_RS08415	COG2195	Cleaves the N-terminal amino acid of tripeptides
EGZ89_RS08420	COG0747	negative chemotaxis
EGZ89_RS08430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGZ89_RS08460	COG2814	Major facilitator Superfamily
EGZ89_RS08470	COG3708	Transcriptional regulator
EGZ89_RS08470	COG2207	Transcriptional regulator
EGZ89_RS08485	COG4290	ribonuclease
EGZ89_RS08505	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGZ89_RS08545	COG0840	transmembrane signaling receptor activity
EGZ89_RS08595	COG1309	transcriptional regulator
EGZ89_RS08610	COG4771	TonB-dependent receptor
EGZ89_RS08610	COG1629	transport
EGZ89_RS08610	COG4771	TonB-dependent receptor
EGZ89_RS08610	COG1629	transport
EGZ89_RS08620	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EGZ89_RS08625	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EGZ89_RS08635	COG2707	UPF0756 membrane protein
EGZ89_RS08650	COG0339	signal peptide processing
EGZ89_RS08655	COG0402	S-adenosylhomocysteine deaminase activity
EGZ89_RS08660	COG4221	oxidoreductase activity
EGZ89_RS08675	COG0477	Major facilitator Superfamily
EGZ89_RS08685	COG1940	carbohydrate kinase activity
EGZ89_RS08690	COG0583	DNA-binding transcription factor activity
EGZ89_RS08695	COG2814	Major facilitator Superfamily
EGZ89_RS08715	COG5339	Protein conserved in bacteria
EGZ89_RS08720	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EGZ89_RS08725	COG0673	inositol 2-dehydrogenase activity
EGZ89_RS08735	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGZ89_RS08745	COG1879	ABC-type sugar transport system periplasmic component
EGZ89_RS08750	COG1069	ribulokinase activity
EGZ89_RS08755	COG2160	L-arabinose isomerase activity
EGZ89_RS08765	COG4657	Part of a membrane complex involved in electron transport
EGZ89_RS08770	COG2878	Part of a membrane complex involved in electron transport
EGZ89_RS08775	COG4656	Part of a membrane complex involved in electron transport
EGZ89_RS08780	COG4658	electron transport chain
EGZ89_RS08785	COG4659	FMN binding
EGZ89_RS08790	COG4660	Part of a membrane complex involved in electron transport
EGZ89_RS08795	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EGZ89_RS08810	COG1309	transcriptional regulator
EGZ89_RS08820	COG0625	glutathione transferase activity
EGZ89_RS08830	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EGZ89_RS08835	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EGZ89_RS08840	COG0259	pyridoxamine-phosphate oxidase activity
EGZ89_RS08845	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EGZ89_RS08865	COG3313	Fe-S protein
EGZ89_RS08885	COG2194	sulfuric ester hydrolase activity
EGZ89_RS08895	COG1902	pentaerythritol trinitrate reductase activity
EGZ89_RS08900	COG0346	lactoylglutathione lyase activity
EGZ89_RS08910	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EGZ89_RS08915	COG0791	NLP P60 protein
EGZ89_RS08920	COG1609	Transcriptional regulator
EGZ89_RS08925	COG0583	DNA-binding transcription factor activity
EGZ89_RS08930	COG2814	Major facilitator Superfamily
EGZ89_RS08935	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EGZ89_RS08940	COG0307	riboflavin synthase, alpha
EGZ89_RS08960	COG0469	pyruvate kinase activity
EGZ89_RS08970	COG2166	iron-sulfur cluster assembly
EGZ89_RS08980	COG0719	Fe-S assembly protein
EGZ89_RS08985	COG0396	ATPase activity
EGZ89_RS08990	COG0719	Fe-S assembly protein
EGZ89_RS08995	COG0316	Belongs to the HesB IscA family
EGZ89_RS09005	COG0247	lactate metabolic process
EGZ89_RS09005	COG0277	FAD linked oxidase domain protein
EGZ89_RS09010	COG0628	permease
EGZ89_RS09020	COG0574	Belongs to the PEP-utilizing enzyme family
EGZ89_RS09020	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EGZ89_RS09025	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EGZ89_RS09035	COG3720	iron ion transport
EGZ89_RS09040	COG4558	Periplasmic binding protein
EGZ89_RS09045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGZ89_RS09050	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EGZ89_RS09055	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EGZ89_RS09065	COG0791	NLP P60 protein
EGZ89_RS09070	COG0386	Belongs to the glutathione peroxidase family
EGZ89_RS09080	COG0776	regulation of translation
EGZ89_RS09090	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EGZ89_RS09100	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EGZ89_RS09105	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EGZ89_RS09115	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EGZ89_RS09120	COG3137	Salt-induced outer membrane protein
EGZ89_RS09130	COG3001	Fructosamine kinase
EGZ89_RS09140	COG1988	membrane-bound metal-dependent
EGZ89_RS09155	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EGZ89_RS09160	COG2814	Major facilitator Superfamily
EGZ89_RS09165	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EGZ89_RS09170	COG0322	excinuclease ABC activity
EGZ89_RS09175	COG3678	ATP-independent chaperone mediated protein folding
EGZ89_RS09180	COG2988	succinylglutamate desuccinylase activity
EGZ89_RS09185	COG3724	N-succinylarginine dihydrolase activity
EGZ89_RS09190	COG1012	belongs to the aldehyde dehydrogenase family
EGZ89_RS09205	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EGZ89_RS09210	COG4932	domain protein
EGZ89_RS09240	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
EGZ89_RS09270	COG0387	Pfam Sodium calcium exchanger
EGZ89_RS09275	COG3187	Heat shock protein
EGZ89_RS09280	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EGZ89_RS09285	COG2912	Transglutaminase-like superfamily
EGZ89_RS09295	COG2890	protein-(glutamine-N5) methyltransferase activity
EGZ89_RS09300	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EGZ89_RS09305	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EGZ89_RS09310	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
EGZ89_RS09315	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EGZ89_RS09330	COG0193	aminoacyl-tRNA hydrolase activity
EGZ89_RS09340	COG0659	secondary active sulfate transmembrane transporter activity
EGZ89_RS09345	COG0012	GTP binding
EGZ89_RS09355	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EGZ89_RS09505	COG3290	protein histidine kinase activity
EGZ89_RS09510	COG4565	transcriptional regulatory protein
EGZ89_RS09530	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EGZ89_RS09530	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EGZ89_RS09545	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EGZ89_RS09555	COG2261	transglycosylase associated protein
EGZ89_RS09560	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
EGZ89_RS09565	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
EGZ89_RS09575	COG1619	proteins homologs of microcin C7 resistance protein MccF
EGZ89_RS09615	COG0538	isocitrate dehydrogenase activity
EGZ89_RS09635	COG2915	High frequency lysogenization protein hflD homolog
EGZ89_RS09640	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EGZ89_RS09645	COG0745	RESPONSE REGULATOR receiver
EGZ89_RS09655	COG2850	peptidyl-arginine hydroxylation
EGZ89_RS09660	COG1396	sequence-specific DNA binding
EGZ89_RS09665	COG3135	benzoate transporter
EGZ89_RS09675	COG1940	carbohydrate kinase activity
EGZ89_RS09685	COG4591	ABC-type transport system involved in lipoprotein release permease component
EGZ89_RS09695	COG4591	ABC-type transport system involved in lipoprotein release permease component
EGZ89_RS09700	COG2199	diguanylate cyclase activity
EGZ89_RS09720	COG0835	chemotaxis
EGZ89_RS09720	COG0784	Response regulator, receiver
EGZ89_RS09725	COG1677	Flagellar hook-basal body complex protein FliE
EGZ89_RS09735	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EGZ89_RS09740	COG1317	bacterial-type flagellum organization
EGZ89_RS09760	COG1580	Controls the rotational direction of flagella during chemotaxis
EGZ89_RS09765	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EGZ89_RS09815	COG1215	transferase activity, transferring glycosyl groups
EGZ89_RS09820	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EGZ89_RS09825	COG3134	Outer membrane lipoprotein
EGZ89_RS09830	COG1252	NADH dehydrogenase
EGZ89_RS09840	COG1472	Belongs to the glycosyl hydrolase 3 family
EGZ89_RS09850	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
EGZ89_RS09860	COG0537	adenosine 5'-monophosphoramidase activity
EGZ89_RS09865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGZ89_RS09865	COG1263	PTS System
EGZ89_RS09870	COG0084	hydrolase, TatD family'
EGZ89_RS09875	COG0470	DNA polymerase III
EGZ89_RS09880	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EGZ89_RS09885	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EGZ89_RS09890	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EGZ89_RS09895	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EGZ89_RS09900	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EGZ89_RS09910	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EGZ89_RS09915	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EGZ89_RS09920	COG0416	fatty acid biosynthetic process
EGZ89_RS09925	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EGZ89_RS09930	COG1399	metal-binding, possibly nucleic acid-binding protein
EGZ89_RS09935	COG0424	maF-like protein
EGZ89_RS09940	COG0564	pseudouridine synthase activity
EGZ89_RS09945	COG1530	ribonuclease E activity
EGZ89_RS09945	COG1530	ribonuclease E activity
EGZ89_RS09950	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EGZ89_RS09955	COG1256	bacterial-type flagellum assembly
EGZ89_RS09985	COG1749	Flagellar hook protein flgE
EGZ89_RS09990	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EGZ89_RS09995	COG1558	bacterial-type flagellum-dependent cell motility
EGZ89_RS10000	COG1815	bacterial-type flagellum-dependent cell motility
EGZ89_RS10015	COG3418	PFAM FlgN family protein
EGZ89_RS10030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EGZ89_RS10035	COG2999	glutathione oxidoreductase activity
EGZ89_RS10045	COG0418	dihydroorotase activity
EGZ89_RS10065	COG3038	cytochrome b561
EGZ89_RS10080	COG1560	Kdo2-lipid A biosynthetic process
EGZ89_RS10090	COG5645	(Lipo)protein
EGZ89_RS10110	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EGZ89_RS10140	COG1846	Transcriptional regulator
EGZ89_RS10165	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EGZ89_RS10170	COG0322	excinuclease ABC activity
EGZ89_RS10175	COG2197	response regulator
EGZ89_RS10185	COG3136	membrane protein required for alginate biosynthesis
EGZ89_RS10195	COG2197	response regulator
EGZ89_RS10200	COG1113	amino acid transport
EGZ89_RS10210	COG1309	transcriptional regulator
EGZ89_RS10225	COG1012	belongs to the aldehyde dehydrogenase family
EGZ89_RS10250	COG0670	Belongs to the BI1 family
EGZ89_RS10255	COG2920	part of a sulfur-relay system
EGZ89_RS10265	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EGZ89_RS10270	COG3785	DNA binding
EGZ89_RS10280	COG1803	Methylglyoxal synthase
EGZ89_RS10285	COG0210	DNA helicase
EGZ89_RS10290	COG3304	Inner membrane component domain
EGZ89_RS10295	COG1289	transmembrane transporter activity
EGZ89_RS10300	COG3070	regulator of competence-specific genes
EGZ89_RS10310	COG2885	chlorophyll binding
EGZ89_RS10310	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EGZ89_RS10315	COG3120	sequence-specific DNA binding
EGZ89_RS10320	COG1067	ATP-dependent peptidase activity
EGZ89_RS10325	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EGZ89_RS10330	COG3130	regulation of translation
EGZ89_RS10335	COG3009	Protein conserved in bacteria
EGZ89_RS10340	COG3008	intermembrane lipid transfer
EGZ89_RS10340	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EGZ89_RS10345	COG2995	paraquat-inducible protein a
EGZ89_RS10350	COG0488	(ABC) transporter
EGZ89_RS10355	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EGZ89_RS10355	COG0116	Belongs to the methyltransferase superfamily
EGZ89_RS10360	COG0633	Ferredoxin
EGZ89_RS10360	COG3217	Mosc domain protein beta barrel domain protein
EGZ89_RS10370	COG0167	dihydroorotate dehydrogenase activity
EGZ89_RS10375	COG0431	NADPH-dependent FMN reductase
EGZ89_RS10380	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EGZ89_RS10390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EGZ89_RS10400	COG0308	aminopeptidase N
EGZ89_RS10405	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EGZ89_RS10410	COG0017	Asparaginyl-tRNA synthetase
EGZ89_RS10420	COG1448	Aminotransferase
EGZ89_RS10425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGZ89_RS10430	COG3108	Peptidase M15
EGZ89_RS10435	COG2989	Protein conserved in bacteria
EGZ89_RS10440	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
EGZ89_RS10445	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
EGZ89_RS10450	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
EGZ89_RS10455	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EGZ89_RS10460	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EGZ89_RS10465	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EGZ89_RS10470	COG2835	tetraacyldisaccharide 4'-kinase activity
EGZ89_RS10475	COG1663	tetraacyldisaccharide 4'-kinase activity
EGZ89_RS10485	COG2333	competence protein COMEC
EGZ89_RS10485	COG0658	competence protein
EGZ89_RS10490	COG0776	regulation of translation
EGZ89_RS10495	COG0539	negative regulation of cytoplasmic translation
EGZ89_RS10500	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EGZ89_RS10505	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EGZ89_RS10510	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EGZ89_RS10515	COG1944	ATP diphosphatase activity
EGZ89_RS10525	COG0477	Major facilitator Superfamily
EGZ89_RS10530	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EGZ89_RS10535	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EGZ89_RS10540	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EGZ89_RS10545	COG3107	peptidoglycan biosynthetic process
EGZ89_RS10545	COG1674	ftsk spoiiie
EGZ89_RS10555	COG0492	ferredoxin-NADP+ reductase activity
EGZ89_RS10560	COG4988	ABC transporter
EGZ89_RS10565	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EGZ89_RS10570	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EGZ89_RS10575	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EGZ89_RS10580	COG0542	response to heat
EGZ89_RS10585	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EGZ89_RS10595	COG1278	Cold shock
EGZ89_RS10600	COG3593	DNA synthesis involved in DNA repair
EGZ89_RS10605	COG0028	Belongs to the TPP enzyme family
EGZ89_RS10610	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
EGZ89_RS10620	COG3023	N-Acetylmuramoyl-L-alanine amidase
EGZ89_RS10625	COG0393	Putative heavy-metal-binding
EGZ89_RS10635	COG1126	abc transporter atp-binding protein
EGZ89_RS10640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGZ89_RS10645	COG4215	(ABC) transporter
EGZ89_RS10650	COG4160	amino acid transport
EGZ89_RS10655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGZ89_RS10665	COG1177	transmembrane transport
EGZ89_RS10670	COG1176	ABC-type spermidine putrescine transport system, permease component I
EGZ89_RS10675	COG3842	ATPase activity
EGZ89_RS10680	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EGZ89_RS10715	COG0814	amino acid
EGZ89_RS10720	COG1686	Belongs to the peptidase S11 family
EGZ89_RS10740	COG4172	Belongs to the ABC transporter superfamily
EGZ89_RS10750	COG0303	'Molybdopterin
EGZ89_RS10760	COG0488	(ABC) transporter
EGZ89_RS10765	COG2814	Major facilitator Superfamily
EGZ89_RS10780	COG2814	Major facilitator Superfamily
EGZ89_RS10785	COG1566	PFAM secretion protein HlyD family protein
EGZ89_RS10790	COG1321	iron dependent repressor
EGZ89_RS10795	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EGZ89_RS10805	COG0783	Belongs to the Dps family
EGZ89_RS10810	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EGZ89_RS10815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGZ89_RS10820	COG0765	amino acid transport
EGZ89_RS10825	COG1126	abc transporter atp-binding protein
EGZ89_RS10835	COG0668	transmembrane transport
EGZ89_RS10840	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
EGZ89_RS10850	COG0641	radical SAM
EGZ89_RS10865	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EGZ89_RS10870	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
EGZ89_RS10880	COG1228	amidohydrolase
EGZ89_RS10885	COG0402	S-adenosylhomocysteine deaminase activity
EGZ89_RS10900	COG2986	histidine ammonia-lyase
EGZ89_RS10905	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EGZ89_RS10910	COG1473	amidohydrolase
EGZ89_RS10915	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EGZ89_RS10935	COG0789	Transcriptional regulator
EGZ89_RS10945	COG4221	oxidoreductase activity
EGZ89_RS10960	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EGZ89_RS10980	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EGZ89_RS10995	COG0277	FAD linked oxidase domain protein
EGZ89_RS11005	COG3264	Mechanosensitive ion channel
EGZ89_RS11005	COG1511	domain protein
EGZ89_RS11010	COG1686	Belongs to the peptidase S11 family
EGZ89_RS11020	COG0586	Pfam SNARE associated Golgi protein
EGZ89_RS11025	COG3387	PFAM Glycoside hydrolase 15-related
EGZ89_RS11030	COG1376	ErfK ybiS ycfS ynhG family protein
EGZ89_RS11035	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EGZ89_RS11040	COG0513	Belongs to the DEAD box helicase family
EGZ89_RS11050	COG0670	Belongs to the BI1 family
EGZ89_RS11065	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EGZ89_RS11070	COG0315	cyclic pyranopterin monophosphate synthase activity
EGZ89_RS11075	COG0521	Mo-molybdopterin cofactor biosynthetic process
EGZ89_RS11090	COG0556	nucleotide-excision repair
EGZ89_RS11100	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EGZ89_RS11110	COG0156	8-amino-7-oxononanoate synthase activity
EGZ89_RS11115	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EGZ89_RS11125	COG2130	NADP-dependent
EGZ89_RS11130	COG1881	PFAM PEBP family protein
EGZ89_RS11135	COG2706	6-phosphogluconolactonase activity
EGZ89_RS11140	COG0561	phosphatase activity
EGZ89_RS11150	COG4149	molybdate abc transporter
EGZ89_RS11155	COG0725	ABC transporter, periplasmic molybdate-binding protein
EGZ89_RS11165	COG3585	molybdate ion transport
EGZ89_RS11165	COG2005	Transcriptional regulator
EGZ89_RS11170	COG1119	ATPase activity
EGZ89_RS11180	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EGZ89_RS11185	COG2017	converts alpha-aldose to the beta-anomer
EGZ89_RS11190	COG0588	phosphoglycerate mutase activity
EGZ89_RS11210	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EGZ89_RS11220	COG1230	cation diffusion facilitator family transporter
EGZ89_RS11285	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
EGZ89_RS11290	COG2885	chlorophyll binding
EGZ89_RS11295	COG0823	Involved in the tonB-independent uptake of proteins
EGZ89_RS11300	COG3064	Membrane
EGZ89_RS11305	COG0848	biopolymer transport protein
EGZ89_RS11310	COG0811	peptide transport
EGZ89_RS11315	COG0824	Thioesterase
EGZ89_RS11320	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EGZ89_RS11325	COG0045	succinate-CoA ligase (ADP-forming) activity
EGZ89_RS11330	COG0508	dehydrogenase complex catalyzes the overall conversion of
EGZ89_RS11335	COG0567	Dehydrogenase, E1 component
EGZ89_RS11340	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EGZ89_RS11345	COG1053	succinate dehydrogenase
EGZ89_RS11350	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EGZ89_RS11355	COG2009	succinate dehydrogenase
EGZ89_RS11360	COG0372	Belongs to the citrate synthase family
EGZ89_RS11370	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EGZ89_RS11375	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EGZ89_RS11380	COG1984	allophanate hydrolase subunit 2
EGZ89_RS11385	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EGZ89_RS11395	COG0415	Belongs to the DNA photolyase family
EGZ89_RS11400	COG3272	Protein of unknown function (DUF1722)
EGZ89_RS11410	COG0745	RESPONSE REGULATOR receiver
EGZ89_RS11415	COG0033	Phosphoglucomutase
EGZ89_RS11420	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
EGZ89_RS11425	COG0596	Alpha beta hydrolase
EGZ89_RS11440	COG0735	belongs to the Fur family
EGZ89_RS11445	COG0814	amino acid
EGZ89_RS11450	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EGZ89_RS11460	COG0363	glucosamine-6-phosphate deaminase activity
EGZ89_RS11465	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EGZ89_RS11470	COG1846	Transcriptional regulator
EGZ89_RS11470	COG1940	carbohydrate kinase activity
EGZ89_RS11475	COG0647	UMP catabolic process
EGZ89_RS11480	COG0367	asparagine synthase
EGZ89_RS11515	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGZ89_RS11520	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EGZ89_RS11525	COG1702	phosphate starvation-inducible protein PhoH
EGZ89_RS11530	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EGZ89_RS11535	COG4535	Mg2 and Co2 transporter CorC
EGZ89_RS11540	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EGZ89_RS11550	COG0765	amino acid transport
EGZ89_RS11555	COG0765	amino acid transport
EGZ89_RS11560	COG1126	abc transporter atp-binding protein
EGZ89_RS11565	COG2888	peptidyl-tyrosine sulfation
EGZ89_RS11570	COG0495	leucyl-tRNA aminoacylation
EGZ89_RS11575	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
EGZ89_RS11580	COG1466	dna polymerase III delta subunit
EGZ89_RS11590	COG0799	negative regulation of ribosome biogenesis
EGZ89_RS11595	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EGZ89_RS11600	COG0768	penicillin binding
EGZ89_RS11605	COG0772	Belongs to the SEDS family
EGZ89_RS11610	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EGZ89_RS11615	COG1686	Belongs to the peptidase S11 family
EGZ89_RS11620	COG2921	Belongs to the UPF0250 family
EGZ89_RS11625	COG0321	lipoyl(octanoyl) transferase activity
EGZ89_RS11630	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EGZ89_RS11635	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EGZ89_RS11640	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EGZ89_RS11655	COG2610	gluconate transmembrane transporter activity
EGZ89_RS11660	COG2610	gluconate transmembrane transporter activity
EGZ89_RS11665	COG3622	Belongs to the hyi family
EGZ89_RS11670	COG0235	Class ii aldolase
EGZ89_RS11675	COG3395	kinase activity
EGZ89_RS11680	COG2084	Dehydrogenase
EGZ89_RS11685	COG1349	DNA-binding transcription factor activity
EGZ89_RS11700	COG1271	oxidase subunit
EGZ89_RS11705	COG1294	oxidase, subunit
EGZ89_RS11715	COG2076	Multidrug Resistance protein
EGZ89_RS11720	COG2076	Multidrug Resistance protein
EGZ89_RS11725	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EGZ89_RS11730	COG0726	polysaccharide deacetylase
EGZ89_RS11735	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGZ89_RS11735	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EGZ89_RS11740	COG0463	Glycosyl transferase, family 2
EGZ89_RS11745	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EGZ89_RS11755	COG4993	Dehydrogenase
EGZ89_RS11760	COG4772	TonB-dependent receptor
EGZ89_RS11775	COG4172	Belongs to the ABC transporter superfamily
EGZ89_RS11795	COG1410	methionine synthase
EGZ89_RS11795	COG0646	methionine synthase
EGZ89_RS11810	COG1764	response to oxidative stress
EGZ89_RS11835	COG0582	viral genome integration into host DNA
EGZ89_RS11845	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EGZ89_RS11850	COG2501	S4 domain
EGZ89_RS11855	COG1064	alcohol dehydrogenase
EGZ89_RS11860	COG0215	cysteine-tRNA ligase activity
EGZ89_RS11865	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EGZ89_RS11875	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EGZ89_RS11880	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EGZ89_RS11885	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EGZ89_RS11890	COG4181	ATPase activity
EGZ89_RS11895	COG2755	lipolytic protein G-D-S-L family
EGZ89_RS11920	COG0300	oxidoreductase activity
EGZ89_RS11925	COG3118	belongs to the thioredoxin family
EGZ89_RS11930	COG0330	HflC and HflK could
EGZ89_RS11935	COG1585	Membrane protein implicated in regulation of membrane protease activity
EGZ89_RS11945	COG2217	Heavy metal translocating P-type atpase
EGZ89_RS11950	COG3735	TraB family
EGZ89_RS11955	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EGZ89_RS11960	COG0583	DNA-binding transcription factor activity
EGZ89_RS11970	COG0737	Belongs to the 5'-nucleotidase family
EGZ89_RS11975	COG2223	nitrite transmembrane transporter activity
EGZ89_RS11980	COG4651	solute:proton antiporter activity
EGZ89_RS11980	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EGZ89_RS11990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGZ89_RS11995	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EGZ89_RS12000	COG0563	adenylate kinase activity
EGZ89_RS12025	COG0583	DNA-binding transcription factor activity
EGZ89_RS12030	COG0326	Molecular chaperone. Has ATPase activity
EGZ89_RS12035	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EGZ89_RS12040	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EGZ89_RS12050	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EGZ89_RS12055	COG2832	Protein of unknown function (DUF454)
EGZ89_RS12075	COG1309	transcriptional regulator
EGZ89_RS12080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGZ89_RS12085	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGZ89_RS12090	COG0254	rRNA binding
EGZ89_RS12095	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EGZ89_RS12120	COG3695	enzyme binding
EGZ89_RS12125	COG3126	Type III secretion system lipoprotein chaperone (YscW)
EGZ89_RS12130	COG1946	Acyl-CoA thioesterase
EGZ89_RS12135	COG0004	ammonium transporteR
EGZ89_RS12140	COG0347	Belongs to the P(II) protein family
EGZ89_RS12145	COG1132	(ABC) transporter
EGZ89_RS12150	COG1132	(ABC) transporter
EGZ89_RS12155	COG1522	sequence-specific DNA binding
EGZ89_RS12165	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EGZ89_RS12170	COG0824	Thioesterase
EGZ89_RS12175	COG1555	photosystem II stabilization
EGZ89_RS12180	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EGZ89_RS12185	COG0776	regulation of translation
EGZ89_RS12200	COG0740	serine-type endopeptidase activity
EGZ89_RS12215	COG0544	peptidyl-prolyl cis-trans isomerase activity
EGZ89_RS12220	COG0271	Belongs to the BolA IbaG family
EGZ89_RS12225	COG3056	Lipoprotein
EGZ89_RS12230	COG2223	nitrite transmembrane transporter activity
EGZ89_RS12235	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EGZ89_RS12240	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EGZ89_RS12245	COG1845	cytochrome c oxidase, subunit III
EGZ89_RS12250	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EGZ89_RS12255	COG0109	protoheme IX farnesyltransferase activity
EGZ89_RS12260	COG2814	Major facilitator Superfamily
EGZ89_RS12265	COG1666	GTP binding
EGZ89_RS12270	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EGZ89_RS12280	COG0301	tRNA thio-modification
EGZ89_RS12280	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EGZ89_RS12285	COG1722	exodeoxyribonuclease VII activity
EGZ89_RS12290	COG0142	geranyltranstransferase activity
EGZ89_RS12295	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EGZ89_RS12300	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EGZ89_RS12305	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EGZ89_RS12310	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EGZ89_RS12315	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EGZ89_RS12320	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EGZ89_RS12320	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EGZ89_RS12325	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EGZ89_RS12330	COG1652	LysM domain
EGZ89_RS12340	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EGZ89_RS12345	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EGZ89_RS12350	COG1862	Preprotein translocase
EGZ89_RS12355	COG0343	queuine tRNA-ribosyltransferase activity
EGZ89_RS12360	COG2246	polysaccharide biosynthetic process
EGZ89_RS12375	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EGZ89_RS12380	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
EGZ89_RS12385	COG0450	alkyl hydroperoxide reductase
EGZ89_RS12400	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EGZ89_RS12410	COG5002	protein histidine kinase activity
EGZ89_RS12420	COG0420	3'-5' exonuclease activity
EGZ89_RS12425	COG0419	ATPase involved in DNA repair
EGZ89_RS12465	COG2974	May be involved in recombination
EGZ89_RS12470	COG3123	guanosine phosphorylase activity
EGZ89_RS12475	COG4126	flavin adenine dinucleotide binding
EGZ89_RS12500	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EGZ89_RS12505	COG3416	Protein conserved in bacteria
EGZ89_RS12510	COG1671	Belongs to the UPF0178 family
EGZ89_RS12515	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EGZ89_RS12530	COG3250	beta-galactosidase activity
EGZ89_RS12535	COG1278	Cold shock
EGZ89_RS12555	COG0747	negative chemotaxis
EGZ89_RS12560	COG0601	transmembrane transport
EGZ89_RS12570	COG0444	Belongs to the ABC transporter superfamily
EGZ89_RS12575	COG4608	Belongs to the ABC transporter superfamily
EGZ89_RS12630	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EGZ89_RS12635	COG2832	Protein of unknown function (DUF454)
EGZ89_RS12640	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EGZ89_RS12645	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EGZ89_RS12665	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
EGZ89_RS12670	COG2195	Cleaves the N-terminal amino acid of tripeptides
EGZ89_RS12680	COG3034	peptidoglycan biosynthetic process
EGZ89_RS12685	COG0121	glutamine amidotransferase
EGZ89_RS12690	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EGZ89_RS12695	COG1960	acyl-CoA dehydrogenase activity
EGZ89_RS12700	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EGZ89_RS12710	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EGZ89_RS12715	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
EGZ89_RS12735	COG0436	Aminotransferase
EGZ89_RS12740	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EGZ89_RS12745	COG2233	PERMEase
EGZ89_RS12750	COG2351	hydroxyisourate hydrolase activity
EGZ89_RS12765	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EGZ89_RS12780	COG0765	amino acid transport
EGZ89_RS12820	COG1715	Restriction endonuclease
EGZ89_RS12825	COG2189	Belongs to the N(4) N(6)-methyltransferase family
EGZ89_RS12850	COG1953	Uracil, thiamine, allantoin
EGZ89_RS12860	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EGZ89_RS12865	COG0328	RNA-DNA hybrid ribonuclease activity
EGZ89_RS12870	COG2226	methyltransferase
EGZ89_RS12875	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGZ89_RS12880	COG0741	lytic transglycosylase activity
EGZ89_RS12880	COG1388	LysM domain
EGZ89_RS12890	COG3021	interspecies interaction between organisms
EGZ89_RS12925	COG0542	response to heat
EGZ89_RS12935	COG0564	pseudouridine synthase activity
EGZ89_RS12940	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EGZ89_RS12945	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EGZ89_RS12950	COG1605	Chorismate mutase
EGZ89_RS12950	COG0077	Prephenate dehydratase
EGZ89_RS12955	COG1605	Chorismate mutase
EGZ89_RS12955	COG0287	Prephenate dehydrogenase
EGZ89_RS12960	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EGZ89_RS12980	COG0335	large ribosomal subunit rRNA binding
EGZ89_RS12995	COG0228	four-way junction DNA binding
EGZ89_RS13000	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EGZ89_RS13005	COG4137	Cytochrome C assembly protein
EGZ89_RS13010	COG4536	flavin adenine dinucleotide binding
EGZ89_RS13020	COG2918	glutathione biosynthetic process
EGZ89_RS13025	COG1238	metal cluster binding
EGZ89_RS13030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EGZ89_RS13055	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EGZ89_RS13070	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EGZ89_RS13075	COG1546	Belongs to the CinA family
EGZ89_RS13080	COG2951	lytic endotransglycosylase activity
EGZ89_RS13085	COG5455	response to cobalt ion
EGZ89_RS13105	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EGZ89_RS13245	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EGZ89_RS13250	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EGZ89_RS13255	COG4942	peptidase
EGZ89_RS13255	COG1388	LysM domain
EGZ89_RS13260	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EGZ89_RS13265	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EGZ89_RS13270	COG0585	pseudouridine synthase activity
EGZ89_RS13275	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EGZ89_RS13280	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EGZ89_RS13285	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EGZ89_RS13295	COG0529	Catalyzes the synthesis of activated sulfate
EGZ89_RS13300	COG2895	sulfate adenylyltransferase (ATP) activity
EGZ89_RS13305	COG0175	sulfate reduction
EGZ89_RS13310	COG1648	precorrin-2 dehydrogenase activity
EGZ89_RS13310	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EGZ89_RS13320	COG0175	sulfate reduction
EGZ89_RS13325	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EGZ89_RS13335	COG0720	synthase
EGZ89_RS13345	COG0765	amino acid transport
EGZ89_RS13350	COG1126	abc transporter atp-binding protein
EGZ89_RS13355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGZ89_RS13360	COG0602	queuosine metabolic process
EGZ89_RS13365	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EGZ89_RS13365	COG2755	lipolytic protein G-D-S-L family
EGZ89_RS13370	COG0148	phosphopyruvate hydratase activity
EGZ89_RS13375	COG0504	CTP synthase activity
EGZ89_RS13380	COG3956	TIGRFAM MazG family protein
EGZ89_RS13385	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EGZ89_RS13390	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EGZ89_RS13400	COG1929	Belongs to the glycerate kinase type-1 family
EGZ89_RS13405	COG0716	FMN binding
EGZ89_RS13410	COG0564	pseudouridine synthase activity
EGZ89_RS13415	COG3098	single-species biofilm formation
EGZ89_RS13425	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EGZ89_RS13425	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EGZ89_RS13430	COG1611	Belongs to the LOG family
EGZ89_RS13435	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EGZ89_RS13440	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
EGZ89_RS13445	COG2363	Small membrane protein
EGZ89_RS13450	COG0583	DNA-binding transcription factor activity
EGZ89_RS13460	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EGZ89_RS13465	COG2166	iron-sulfur cluster assembly
EGZ89_RS13470	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EGZ89_RS13475	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
EGZ89_RS13495	COG0860	N-Acetylmuramoyl-L-alanine amidase
EGZ89_RS13500	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EGZ89_RS13500	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EGZ89_RS13510	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EGZ89_RS13515	COG1074	ATP-dependent DNA helicase activity
EGZ89_RS13525	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EGZ89_RS13540	COG4795	General secretion pathway protein
EGZ89_RS13550	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
EGZ89_RS13555	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EGZ89_RS13560	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EGZ89_RS13570	COG1051	belongs to the nudix hydrolase family
EGZ89_RS13575	COG3066	DNA modification
EGZ89_RS13580	COG0861	Integral membrane protein TerC family
EGZ89_RS13590	COG0667	Aldo Keto reductase
EGZ89_RS13600	COG0204	Acyl-transferase
EGZ89_RS13600	COG0318	PFAM AMP-dependent synthetase and ligase
EGZ89_RS13625	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGZ89_RS13635	COG0768	penicillin binding
EGZ89_RS13640	COG2831	hemolysin activation secretion protein
EGZ89_RS13645	COG3210	domain, Protein
EGZ89_RS13660	COG3210	domain, Protein
EGZ89_RS13675	COG3210	domain, Protein
EGZ89_RS13690	COG3210	domain, Protein
EGZ89_RS13705	COG3210	domain, Protein
EGZ89_RS13720	COG1609	Transcriptional regulator
EGZ89_RS13730	COG0583	DNA-binding transcription factor activity
EGZ89_RS13735	COG2814	Major facilitator Superfamily
EGZ89_RS13745	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EGZ89_RS13755	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EGZ89_RS13765	COG4974	Belongs to the 'phage' integrase family
EGZ89_RS13775	COG0697	spore germination
EGZ89_RS13780	COG0716	FMN binding
EGZ89_RS13790	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EGZ89_RS13795	COG0354	folic acid binding
EGZ89_RS13800	COG1272	protein, Hemolysin III
EGZ89_RS13810	COG1028	Short-chain dehydrogenase reductase Sdr
EGZ89_RS13815	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EGZ89_RS13815	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EGZ89_RS13820	COG0509	glycine decarboxylation via glycine cleavage system
EGZ89_RS13825	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EGZ89_RS13830	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGZ89_RS13835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGZ89_RS13840	COG0006	proline dipeptidase activity
EGZ89_RS13845	COG3079	Belongs to the UPF0149 family
EGZ89_RS13850	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EGZ89_RS13860	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EGZ89_RS13865	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EGZ89_RS13875	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EGZ89_RS13880	COG0583	DNA-binding transcription factor activity
EGZ89_RS13890	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EGZ89_RS13900	COG0673	inositol 2-dehydrogenase activity
EGZ89_RS13915	COG2072	flavoprotein involved in K transport
EGZ89_RS13930	COG0668	transmembrane transport
EGZ89_RS13935	COG0191	fructose-bisphosphate aldolase activity
EGZ89_RS13940	COG0126	phosphoglycerate kinase activity
EGZ89_RS13945	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EGZ89_RS13950	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EGZ89_RS13955	COG0501	Belongs to the peptidase M48B family
EGZ89_RS13995	COG1166	arginine decarboxylase activity
EGZ89_RS14000	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EGZ89_RS14005	COG2814	Major facilitator Superfamily
EGZ89_RS14010	COG3091	SprT-like family
EGZ89_RS14015	COG2356	endonuclease I
EGZ89_RS14020	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EGZ89_RS14030	COG1678	Uncharacterized ACR, COG1678
EGZ89_RS14035	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EGZ89_RS14045	COG4232	protein-disulfide reductase activity
EGZ89_RS14060	COG2805	Type II/IV secretion system protein
EGZ89_RS14065	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EGZ89_RS14070	COG0762	integral membrane protein
EGZ89_RS14075	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EGZ89_RS14080	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EGZ89_RS14090	COG3171	Protein conserved in bacteria
EGZ89_RS14105	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
EGZ89_RS14110	COG0741	lytic transglycosylase activity
EGZ89_RS14120	COG1982	Orn Lys Arg decarboxylase major
EGZ89_RS14185	COG3179	chitinase
EGZ89_RS14205	COG0583	DNA-binding transcription factor activity
EGZ89_RS14220	COG5297	Belongs to the glycosyl hydrolase family 6
EGZ89_RS14310	COG2197	response regulator
EGZ89_RS14340	COG1157	protein secretion by the type III secretion system
EGZ89_RS14365	COG4794	Type iii secretion
EGZ89_RS14375	COG4792	protein secretion
EGZ89_RS14390	COG0151	Belongs to the GarS family
EGZ89_RS14395	COG0151	Belongs to the GarS family
EGZ89_RS14400	COG1834	amidinotransferase
EGZ89_RS14430	COG1966	Carbon starvation protein
EGZ89_RS14435	COG2879	small protein
EGZ89_RS14445	COG3275	phosphorelay sensor kinase activity
EGZ89_RS14465	COG1522	sequence-specific DNA binding
EGZ89_RS14490	COG1609	Transcriptional regulator
EGZ89_RS14500	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EGZ89_RS14505	COG1447	Phosphotransferase system cellobiose-specific component IIA
EGZ89_RS14510	COG2723	6-phospho-beta-galactosidase activity
EGZ89_RS14515	COG2723	6-phospho-beta-galactosidase activity
EGZ89_RS14530	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EGZ89_RS14535	COG1528	Iron-storage protein
EGZ89_RS14545	COG0671	phosphoesterase, PA-phosphatase related
EGZ89_RS14570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EGZ89_RS14600	COG1028	Short-chain dehydrogenase reductase Sdr
EGZ89_RS14610	COG0848	biopolymer transport protein
EGZ89_RS14620	COG0626	cystathionine gamma-synthase activity
EGZ89_RS14625	COG0586	Pfam SNARE associated Golgi protein
EGZ89_RS14630	COG0076	glutamate decarboxylase activity
EGZ89_RS14635	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EGZ89_RS14640	COG2207	Transcriptional regulator
EGZ89_RS14645	COG0656	L-ascorbic acid biosynthetic process
EGZ89_RS14650	COG2132	Multicopper oxidase
EGZ89_RS14710	COG0318	PFAM AMP-dependent synthetase and ligase
EGZ89_RS14710	COG3321	synthase
EGZ89_RS14710	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EGZ89_RS14710	COG1028	Short-chain dehydrogenase reductase Sdr
EGZ89_RS14710	COG0300	oxidoreductase activity
EGZ89_RS14725	COG0167	dihydroorotate dehydrogenase activity
EGZ89_RS14750	COG3150	esterase
EGZ89_RS14755	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EGZ89_RS14760	COG3151	Protein conserved in bacteria
EGZ89_RS14765	COG0494	nUDIX hydrolase
EGZ89_RS14770	COG1538	Outer membrane efflux protein
EGZ89_RS14775	COG5463	Belongs to the UPF0441 family
EGZ89_RS14780	COG0754	glutathionylspermidine amidase activity
EGZ89_RS14785	COG3384	dioxygenase
EGZ89_RS14790	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EGZ89_RS14800	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EGZ89_RS14800	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
EGZ89_RS14810	COG3025	triphosphatase activity
EGZ89_RS14815	COG4991	sh3 domain protein
EGZ89_RS14820	COG0617	tRNA 3'-terminal CCA addition
EGZ89_RS14825	COG1968	undecaprenyl-diphosphatase activity
EGZ89_RS14830	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EGZ89_RS14835	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EGZ89_RS14840	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EGZ89_RS14845	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EGZ89_RS14850	COG0358	DNA primase activity
EGZ89_RS14860	COG3663	DNA glycosylase
EGZ89_RS14875	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EGZ89_RS14880	COG3423	Transcriptional regulator
EGZ89_RS14890	COG1464	Belongs to the NlpA lipoprotein family
EGZ89_RS14895	COG3012	SEC-C Motif Domain Protein
EGZ89_RS14895	COG3318	Belongs to the UPF0149 family
EGZ89_RS14900	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EGZ89_RS14940	COG2003	Belongs to the UPF0758 family
EGZ89_RS14990	COG1715	Restriction endonuclease
EGZ89_RS15010	COG0582	viral genome integration into host DNA
EGZ89_RS15025	COG0433	COG0433 Predicted ATPase
EGZ89_RS15030	COG2733	membrane
EGZ89_RS15035	COG0795	lipopolysaccharide-transporting ATPase activity
EGZ89_RS15040	COG0795	lipopolysaccharide-transporting ATPase activity
EGZ89_RS15045	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EGZ89_RS15050	COG2927	DNA polymerase III (CHI subunit)
EGZ89_RS15055	COG0525	valine-tRNA ligase activity
EGZ89_RS15065	COG2271	Major facilitator Superfamily
EGZ89_RS15080	COG0456	acetyltransferase
EGZ89_RS15085	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
EGZ89_RS15090	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EGZ89_RS15100	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
EGZ89_RS15110	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EGZ89_RS15115	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EGZ89_RS15125	COG0602	queuosine metabolic process
EGZ89_RS15130	COG3766	membrane
EGZ89_RS15135	COG2827	Endonuclease containing a URI domain
EGZ89_RS15140	COG3153	acetyltransferase
EGZ89_RS15145	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGZ89_RS15150	COG0513	Belongs to the DEAD box helicase family
EGZ89_RS15165	COG1185	polyribonucleotide nucleotidyltransferase activity
EGZ89_RS15170	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EGZ89_RS15175	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EGZ89_RS15180	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EGZ89_RS15190	COG0195	Participates in both transcription termination and antitermination
EGZ89_RS15195	COG0779	Required for maturation of 30S ribosomal subunits
EGZ89_RS15210	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EGZ89_RS15215	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EGZ89_RS15220	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EGZ89_RS15230	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EGZ89_RS15235	COG1534	Rna-binding protein
EGZ89_RS15245	COG2027	D-alanyl-D-alanine carboxypeptidase
EGZ89_RS15250	COG0745	RESPONSE REGULATOR receiver
EGZ89_RS15255	COG0642	Histidine kinase
EGZ89_RS15260	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EGZ89_RS15270	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EGZ89_RS15275	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EGZ89_RS15280	COG0142	geranyltranstransferase activity
EGZ89_RS15285	COG3423	Transcriptional regulator
EGZ89_RS15290	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EGZ89_RS15295	COG5007	Belongs to the BolA IbaG family
EGZ89_RS15300	COG3113	response to antibiotic
EGZ89_RS15305	COG2854	intermembrane phospholipid transfer
EGZ89_RS15310	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EGZ89_RS15315	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EGZ89_RS15320	COG1127	ABC transporter
EGZ89_RS15325	COG0530	calcium, potassium:sodium antiporter activity
EGZ89_RS15335	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EGZ89_RS15340	COG3117	lipopolysaccharide transmembrane transporter activity
EGZ89_RS15345	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EGZ89_RS15350	COG1137	ATPase activity
EGZ89_RS15355	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EGZ89_RS15370	COG1660	Displays ATPase and GTPase activities
EGZ89_RS15375	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGZ89_RS15385	COG0784	Response regulator, receiver
EGZ89_RS15385	COG5002	protein histidine kinase activity
EGZ89_RS15385	COG2198	Histidine kinase
EGZ89_RS15390	COG0070	glutamate synthase
EGZ89_RS15390	COG0069	glutamate synthase activity
EGZ89_RS15390	COG0067	glutamate synthase
EGZ89_RS15395	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EGZ89_RS15400	COG2969	positive regulation of protein catabolic process
EGZ89_RS15405	COG0625	glutathione transferase activity
EGZ89_RS15410	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EGZ89_RS15415	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EGZ89_RS15420	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EGZ89_RS15425	COG3105	Protein conserved in bacteria
EGZ89_RS15430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EGZ89_RS15435	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EGZ89_RS15440	COG0039	L-malate dehydrogenase activity
EGZ89_RS15445	COG1438	arginine binding
EGZ89_RS15460	COG1289	transmembrane transporter activity
EGZ89_RS15465	COG1566	PFAM secretion protein HlyD family protein
EGZ89_RS15475	COG0583	DNA-binding transcription factor activity
EGZ89_RS15480	COG0312	modulator of DNA gyrase
EGZ89_RS15485	COG3164	Protein of unknown function
EGZ89_RS15490	COG1530	ribonuclease E activity
EGZ89_RS15500	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EGZ89_RS15505	COG1792	Involved in formation and maintenance of cell shape
EGZ89_RS15510	COG1077	Cell shape determining protein MreB Mrl
EGZ89_RS15515	COG2200	EAL domain
EGZ89_RS15515	COG2199	diguanylate cyclase activity
EGZ89_RS15520	COG0604	alcohol dehydrogenase
EGZ89_RS15525	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EGZ89_RS15535	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EGZ89_RS15540	COG0511	ligase activity, forming carbon-carbon bonds
EGZ89_RS15545	COG0439	Biotin carboxylase
EGZ89_RS15550	COG3924	membrane
EGZ89_RS15555	COG4145	pantothenate transmembrane transporter activity
EGZ89_RS15560	COG2264	protein methyltransferase activity
EGZ89_RS15580	COG1560	Kdo2-lipid A biosynthetic process
EGZ89_RS15585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGZ89_RS15590	COG4597	amino acid ABC transporter
EGZ89_RS15595	COG0765	amino acid transport
EGZ89_RS15600	COG1126	abc transporter atp-binding protein
EGZ89_RS15635	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EGZ89_RS15645	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EGZ89_RS15655	COG0551	DNA topoisomerase type I activity
EGZ89_RS15660	COG2922	Belongs to the Smg family
EGZ89_RS15665	COG0758	DNA mediated transformation
EGZ89_RS15670	COG0242	peptide deformylase activity
EGZ89_RS15675	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EGZ89_RS15680	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EGZ89_RS15680	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EGZ89_RS15690	COG1970	mechanosensitive ion channel activity
EGZ89_RS15700	COG3036	rescue of stalled ribosome
EGZ89_RS15705	COG0789	Transcriptional regulator
EGZ89_RS15715	COG0203	ribosomal protein L17
EGZ89_RS15720	COG0202	RNA polymerase activity
EGZ89_RS15725	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EGZ89_RS15730	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EGZ89_RS15735	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EGZ89_RS15740	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EGZ89_RS15745	COG0201	protein transport
EGZ89_RS15750	COG0200	Binds to the 23S rRNA
EGZ89_RS15755	COG1841	ribosomal large subunit assembly
EGZ89_RS15765	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EGZ89_RS15770	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EGZ89_RS15775	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EGZ89_RS15780	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EGZ89_RS15785	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EGZ89_RS15790	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EGZ89_RS15795	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EGZ89_RS15800	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EGZ89_RS15805	COG0255	Belongs to the universal ribosomal protein uL29 family
EGZ89_RS15810	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EGZ89_RS15820	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EGZ89_RS15825	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EGZ89_RS15830	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EGZ89_RS15835	COG0089	rRNA binding
EGZ89_RS15840	COG0088	Forms part of the polypeptide exit tunnel
EGZ89_RS15845	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EGZ89_RS15850	COG0051	transcription antitermination factor activity, RNA binding
EGZ89_RS15860	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EGZ89_RS15865	COG0049	tRNA binding
EGZ89_RS15870	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EGZ89_RS15875	COG2168	tRNA wobble position uridine thiolation
EGZ89_RS15880	COG2923	Belongs to the DsrF TusC family
EGZ89_RS15885	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
EGZ89_RS15890	COG2964	Protein conserved in bacteria
EGZ89_RS15895	COG0545	Peptidyl-prolyl cis-trans isomerase
EGZ89_RS15900	COG2900	Belongs to the SlyX family
EGZ89_RS15905	COG1047	Peptidyl-prolyl cis-trans
EGZ89_RS15910	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
EGZ89_RS15915	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EGZ89_RS15915	COG0475	glutathione-regulated potassium exporter activity
EGZ89_RS15920	COG2249	NAD(P)H dehydrogenase (quinone) activity
EGZ89_RS15925	COG0488	(ABC) transporter
EGZ89_RS15935	COG2175	clavaminate synthase activity
EGZ89_RS15940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EGZ89_RS15950	COG4521	taurine ABC transporter
EGZ89_RS15960	COG0429	hydrolase of the alpha beta-hydrolase fold
EGZ89_RS15965	COG3089	Belongs to the UPF0270 family
EGZ89_RS15970	COG3954	Phosphoribulokinase
EGZ89_RS15975	COG1765	OsmC-like protein
EGZ89_RS15985	COG1289	transmembrane transporter activity
EGZ89_RS15990	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EGZ89_RS16005	COG0738	Major facilitator superfamily
EGZ89_RS16010	COG0402	S-adenosylhomocysteine deaminase activity
EGZ89_RS16015	COG0402	S-adenosylhomocysteine deaminase activity
EGZ89_RS16040	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EGZ89_RS16050	COG3266	domain, Protein
EGZ89_RS16055	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EGZ89_RS16060	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EGZ89_RS16065	COG4796	Type ii and iii secretion system protein
EGZ89_RS16090	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EGZ89_RS16095	COG0494	nUDIX hydrolase
EGZ89_RS16105	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EGZ89_RS16110	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EGZ89_RS16115	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EGZ89_RS16125	COG0745	RESPONSE REGULATOR receiver
EGZ89_RS16130	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EGZ89_RS16135	COG2183	response to ionizing radiation
EGZ89_RS16140	COG0366	Alpha amylase catalytic
EGZ89_RS16150	COG1040	competence protein
EGZ89_RS16155	COG0316	Belongs to the HesB IscA family
EGZ89_RS16155	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EGZ89_RS16160	COG1640	4-alpha-glucanotransferase
EGZ89_RS16165	COG0058	SHG alpha-glucan phosphorylase activity
EGZ89_RS16170	COG1349	DNA-binding transcription factor activity
EGZ89_RS16175	COG0705	Rhomboid family
EGZ89_RS16180	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EGZ89_RS16185	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EGZ89_RS16200	COG0058	SHG alpha-glucan phosphorylase activity
EGZ89_RS16205	COG0297	glycogen (starch) synthase activity
EGZ89_RS16215	COG1523	belongs to the glycosyl hydrolase 13 family
EGZ89_RS16230	COG2610	gluconate transmembrane transporter activity
EGZ89_RS16235	COG3265	gluconokinase activity
EGZ89_RS16240	COG1609	Transcriptional regulator
EGZ89_RS16245	COG1741	Belongs to the pirin family
EGZ89_RS16250	COG1247	-acetyltransferase
EGZ89_RS16255	COG0405	Gamma-glutamyltransferase
EGZ89_RS16265	COG0584	glycerophosphoryl diester phosphodiesterase
EGZ89_RS16275	COG0395	ABC-type sugar transport system, permease component
EGZ89_RS16285	COG1653	transport
EGZ89_RS16295	COG0411	ABC transporter
EGZ89_RS16300	COG4177	L-phenylalanine transmembrane transporter activity
EGZ89_RS16315	COG0456	acetyltransferase
EGZ89_RS16325	COG2177	Part of the ABC transporter FtsEX involved in
EGZ89_RS16330	COG2884	Cell division ATP-binding protein ftsE
EGZ89_RS16335	COG0552	protein localization to endoplasmic reticulum
EGZ89_RS16340	COG0742	ribosomal rna small subunit methyltransferase
EGZ89_RS16345	COG3776	membrane
EGZ89_RS16350	COG3714	YhhN family
EGZ89_RS16360	COG0425	Belongs to the sulfur carrier protein TusA family
EGZ89_RS16365	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EGZ89_RS16375	COG1082	Xylose isomerase domain protein TIM barrel
EGZ89_RS16380	COG0673	inositol 2-dehydrogenase activity
EGZ89_RS16385	COG3962	Belongs to the TPP enzyme family
EGZ89_RS16390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGZ89_RS16400	COG3718	enzyme involved in inositol metabolism
EGZ89_RS16410	COG0628	permease
EGZ89_RS16415	COG2200	EAL domain
EGZ89_RS16425	COG1064	alcohol dehydrogenase
EGZ89_RS16460	COG2081	HI0933 family
EGZ89_RS16465	COG0306	phosphate transporter
EGZ89_RS16475	COG0589	response to stress
EGZ89_RS16480	COG0742	ribosomal rna small subunit methyltransferase
EGZ89_RS16505	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EGZ89_RS16510	COG1234	tRNA 3'-trailer cleavage
EGZ89_RS16515	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGZ89_RS16525	COG3038	cytochrome b561
EGZ89_RS16550	COG2862	Uncharacterized protein family, UPF0114
EGZ89_RS16575	COG3708	Transcriptional regulator
EGZ89_RS16575	COG2207	Transcriptional regulator
EGZ89_RS16595	COG1132	(ABC) transporter
EGZ89_RS16600	COG0840	transmembrane signaling receptor activity
EGZ89_RS16605	COG3386	PFAM SMP-30 Gluconolaconase
EGZ89_RS16615	COG2205	protein histidine kinase activity
EGZ89_RS16620	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EGZ89_RS16625	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EGZ89_RS16630	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EGZ89_RS16680	COG0673	inositol 2-dehydrogenase activity
EGZ89_RS16695	COG0673	inositol 2-dehydrogenase activity
EGZ89_RS16700	COG1971	Probably functions as a manganese efflux pump
EGZ89_RS16725	COG0477	Major facilitator Superfamily
EGZ89_RS16730	COG2982	Protein involved in outer membrane biogenesis
EGZ89_RS16735	COG2200	EAL domain
EGZ89_RS16750	COG1301	dicarboxylic acid transport
EGZ89_RS16755	COG2199	diguanylate cyclase activity
EGZ89_RS16755	COG2200	EAL domain
EGZ89_RS16765	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EGZ89_RS16775	COG0457	Tetratricopeptide repeat
EGZ89_RS16780	COG1215	transferase activity, transferring glycosyl groups
EGZ89_RS16785	COG1215	transferase activity, transferring glycosyl groups
EGZ89_RS16790	COG2894	cell division
EGZ89_RS16800	COG4608	Belongs to the ABC transporter superfamily
EGZ89_RS16805	COG0444	Belongs to the ABC transporter superfamily
EGZ89_RS16810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EGZ89_RS16815	COG0601	transmembrane transport
EGZ89_RS16820	COG0747	negative chemotaxis
EGZ89_RS16835	COG1764	response to oxidative stress
EGZ89_RS16840	COG1846	Transcriptional regulator
EGZ89_RS16880	COG0246	Mannitol dehydrogenase
EGZ89_RS16890	COG3274	enterobacterial common antigen metabolic process
EGZ89_RS16895	COG0752	glycyl-tRNA synthetase alpha subunit
EGZ89_RS16900	COG0751	glycine-tRNA ligase activity
EGZ89_RS16905	COG1064	alcohol dehydrogenase
EGZ89_RS16910	COG2944	sequence-specific DNA binding
EGZ89_RS16920	COG2213	PTS system mannitol-specific
EGZ89_RS16920	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGZ89_RS16925	COG0246	Mannitol dehydrogenase
EGZ89_RS16930	COG3722	fumarate hydratase activity
EGZ89_RS16950	COG0745	RESPONSE REGULATOR receiver
EGZ89_RS16960	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGZ89_RS16965	COG1129	ABC transporter
EGZ89_RS16970	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EGZ89_RS16975	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EGZ89_RS16980	COG1349	DNA-binding transcription factor activity
EGZ89_RS16990	COG3058	Necessary for formate dehydrogenase activity
EGZ89_RS16995	COG0625	glutathione transferase activity
EGZ89_RS17000	COG2818	Glycosylase
EGZ89_RS17005	COG2885	chlorophyll binding
EGZ89_RS17010	COG1609	Transcriptional regulator
EGZ89_RS17030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGZ89_RS17035	COG2271	Major facilitator Superfamily
EGZ89_RS17040	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EGZ89_RS17055	COG3977	Valine--pyruvate aminotransferase
EGZ89_RS17065	COG5645	(Lipo)protein
EGZ89_RS17070	COG0823	Involved in the tonB-independent uptake of proteins
EGZ89_RS17075	COG0561	phosphatase activity
EGZ89_RS17080	COG0187	DNA topoisomerase II activity
EGZ89_RS17085	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EGZ89_RS17090	COG0592	DNA-directed DNA polymerase activity
EGZ89_RS17095	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EGZ89_RS17100	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EGZ89_RS17105	COG0594	ribonuclease P activity
EGZ89_RS17115	COG0706	membrane insertase activity
EGZ89_RS17120	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EGZ89_RS17125	COG2091	lysine biosynthetic process via aminoadipic acid
EGZ89_RS17130	COG2252	PERMEase
EGZ89_RS17140	COG2814	Major facilitator Superfamily
EGZ89_RS17145	COG0704	Plays a role in the regulation of phosphate uptake
EGZ89_RS17150	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EGZ89_RS17155	COG0581	inorganic phosphate transmembrane transporter activity
EGZ89_RS17160	COG0573	inorganic phosphate transmembrane transporter activity
EGZ89_RS17165	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EGZ89_RS17185	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EGZ89_RS17190	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EGZ89_RS17195	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EGZ89_RS17200	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EGZ89_RS17205	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EGZ89_RS17210	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EGZ89_RS17215	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EGZ89_RS17220	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EGZ89_RS17230	COG0356	it plays a direct role in the translocation of protons across the membrane
EGZ89_RS17235	COG3312	ion transport
EGZ89_RS17240	COG0357	Ribosomal RNA small subunit methyltransferase G
EGZ89_RS17265	COG0583	DNA-binding transcription factor activity
EGZ89_RS17270	COG1012	belongs to the aldehyde dehydrogenase family
EGZ89_RS17280	COG4628	conserved protein (DUF2132)
EGZ89_RS17345	COG1192	Involved in chromosome partitioning
EGZ89_RS17355	COG0500	methyltransferase
EGZ89_RS17360	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EGZ89_RS17380	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine