locus-tag	class	description
HU055_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HU055_RS00010	COG0592	DNA-directed DNA polymerase activity
HU055_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HU055_RS00020	COG0187	DNA topoisomerase II activity
HU055_RS00025	COG0561	phosphatase activity
HU055_RS00030	COG0823	Involved in the tonB-independent uptake of proteins
HU055_RS00035	COG5645	(Lipo)protein
HU055_RS00045	COG3977	Valine--pyruvate aminotransferase
HU055_RS00060	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HU055_RS00065	COG2271	Major facilitator Superfamily
HU055_RS00070	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HU055_RS00090	COG1609	Transcriptional regulator
HU055_RS00095	COG2885	chlorophyll binding
HU055_RS00100	COG2818	Glycosylase
HU055_RS00105	COG0625	glutathione transferase activity
HU055_RS00110	COG3058	Necessary for formate dehydrogenase activity
HU055_RS00120	COG1349	DNA-binding transcription factor activity
HU055_RS00125	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HU055_RS00130	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HU055_RS00135	COG1129	ABC transporter
HU055_RS00140	COG1172	Belongs to the binding-protein-dependent transport system permease family
HU055_RS00150	COG0745	RESPONSE REGULATOR receiver
HU055_RS00170	COG3722	fumarate hydratase activity
HU055_RS00175	COG0246	Mannitol dehydrogenase
HU055_RS00180	COG2213	PTS system mannitol-specific
HU055_RS00180	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HU055_RS00190	COG2944	sequence-specific DNA binding
HU055_RS00195	COG1064	alcohol dehydrogenase
HU055_RS00200	COG0751	glycine-tRNA ligase activity
HU055_RS00205	COG0752	glycyl-tRNA synthetase alpha subunit
HU055_RS00210	COG3274	enterobacterial common antigen metabolic process
HU055_RS00220	COG0246	Mannitol dehydrogenase
HU055_RS00260	COG1846	Transcriptional regulator
HU055_RS00265	COG1764	response to oxidative stress
HU055_RS00280	COG0747	negative chemotaxis
HU055_RS00285	COG0601	transmembrane transport
HU055_RS00290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HU055_RS00295	COG0444	Belongs to the ABC transporter superfamily
HU055_RS00300	COG4608	Belongs to the ABC transporter superfamily
HU055_RS00310	COG2894	cell division
HU055_RS00315	COG1215	transferase activity, transferring glycosyl groups
HU055_RS00320	COG1215	transferase activity, transferring glycosyl groups
HU055_RS00325	COG0457	Tetratricopeptide repeat
HU055_RS00335	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HU055_RS00345	COG2199	diguanylate cyclase activity
HU055_RS00345	COG2200	EAL domain
HU055_RS00350	COG1301	dicarboxylic acid transport
HU055_RS00365	COG2200	EAL domain
HU055_RS00370	COG2982	Protein involved in outer membrane biogenesis
HU055_RS00375	COG0477	Major facilitator Superfamily
HU055_RS00400	COG1971	Probably functions as a manganese efflux pump
HU055_RS00405	COG0673	inositol 2-dehydrogenase activity
HU055_RS00420	COG0673	inositol 2-dehydrogenase activity
HU055_RS00470	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HU055_RS00475	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HU055_RS00480	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
HU055_RS00485	COG2205	protein histidine kinase activity
HU055_RS00495	COG3386	PFAM SMP-30 Gluconolaconase
HU055_RS00500	COG0840	transmembrane signaling receptor activity
HU055_RS00505	COG1132	(ABC) transporter
HU055_RS00525	COG3708	Transcriptional regulator
HU055_RS00525	COG2207	Transcriptional regulator
HU055_RS00550	COG2862	Uncharacterized protein family, UPF0114
HU055_RS00575	COG3038	cytochrome b561
HU055_RS00585	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HU055_RS00590	COG1234	tRNA 3'-trailer cleavage
HU055_RS00595	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HU055_RS00620	COG0742	ribosomal rna small subunit methyltransferase
HU055_RS00625	COG0589	response to stress
HU055_RS00635	COG0306	phosphate transporter
HU055_RS00640	COG2081	HI0933 family
HU055_RS00675	COG1064	alcohol dehydrogenase
HU055_RS00685	COG2200	EAL domain
HU055_RS00690	COG0628	permease
HU055_RS00700	COG3718	enzyme involved in inositol metabolism
HU055_RS00710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HU055_RS00715	COG3962	Belongs to the TPP enzyme family
HU055_RS00720	COG0673	inositol 2-dehydrogenase activity
HU055_RS00725	COG1082	Xylose isomerase domain protein TIM barrel
HU055_RS00735	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HU055_RS00740	COG0425	Belongs to the sulfur carrier protein TusA family
HU055_RS00750	COG3714	YhhN family
HU055_RS00755	COG3776	membrane
HU055_RS00760	COG0742	ribosomal rna small subunit methyltransferase
HU055_RS00765	COG0552	protein localization to endoplasmic reticulum
HU055_RS00770	COG2884	Cell division ATP-binding protein ftsE
HU055_RS00775	COG2177	Part of the ABC transporter FtsEX involved in
HU055_RS00785	COG0456	acetyltransferase
HU055_RS00800	COG4177	L-phenylalanine transmembrane transporter activity
HU055_RS00805	COG0411	ABC transporter
HU055_RS00815	COG1653	transport
HU055_RS00825	COG0395	ABC-type sugar transport system, permease component
HU055_RS00835	COG0584	glycerophosphoryl diester phosphodiesterase
HU055_RS00845	COG0405	Gamma-glutamyltransferase
HU055_RS00850	COG1247	-acetyltransferase
HU055_RS00855	COG1741	Belongs to the pirin family
HU055_RS00860	COG1609	Transcriptional regulator
HU055_RS00865	COG3265	gluconokinase activity
HU055_RS00870	COG2610	gluconate transmembrane transporter activity
HU055_RS00885	COG1523	belongs to the glycosyl hydrolase 13 family
HU055_RS00895	COG0297	glycogen (starch) synthase activity
HU055_RS00900	COG0058	SHG alpha-glucan phosphorylase activity
HU055_RS00915	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HU055_RS00920	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HU055_RS00925	COG0705	Rhomboid family
HU055_RS00930	COG1349	DNA-binding transcription factor activity
HU055_RS00935	COG0058	SHG alpha-glucan phosphorylase activity
HU055_RS00940	COG1640	4-alpha-glucanotransferase
HU055_RS00945	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
HU055_RS00945	COG0316	Belongs to the HesB IscA family
HU055_RS00950	COG1040	competence protein
HU055_RS00960	COG0366	Alpha amylase catalytic
HU055_RS00965	COG2183	response to ionizing radiation
HU055_RS00970	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HU055_RS00975	COG0745	RESPONSE REGULATOR receiver
HU055_RS00985	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HU055_RS00990	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HU055_RS00995	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HU055_RS01005	COG0494	nUDIX hydrolase
HU055_RS01010	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HU055_RS01035	COG4796	Type ii and iii secretion system protein
HU055_RS01040	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HU055_RS01045	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HU055_RS01050	COG3266	domain, Protein
HU055_RS01060	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HU055_RS01085	COG0402	S-adenosylhomocysteine deaminase activity
HU055_RS01090	COG0402	S-adenosylhomocysteine deaminase activity
HU055_RS01095	COG0738	Major facilitator superfamily
HU055_RS01110	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HU055_RS01115	COG1289	transmembrane transporter activity
HU055_RS01125	COG1765	OsmC-like protein
HU055_RS01130	COG3954	Phosphoribulokinase
HU055_RS01135	COG3089	Belongs to the UPF0270 family
HU055_RS01140	COG0429	hydrolase of the alpha beta-hydrolase fold
HU055_RS01150	COG4521	taurine ABC transporter
HU055_RS01160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HU055_RS01165	COG2175	clavaminate synthase activity
HU055_RS01175	COG0488	(ABC) transporter
HU055_RS01180	COG2249	NAD(P)H dehydrogenase (quinone) activity
HU055_RS01190	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HU055_RS01195	COG1047	Peptidyl-prolyl cis-trans
HU055_RS01200	COG2900	Belongs to the SlyX family
HU055_RS01205	COG0545	Peptidyl-prolyl cis-trans isomerase
HU055_RS01210	COG2964	Protein conserved in bacteria
HU055_RS01215	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HU055_RS01220	COG2923	Belongs to the DsrF TusC family
HU055_RS01225	COG2168	tRNA wobble position uridine thiolation
HU055_RS01230	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HU055_RS01235	COG0049	tRNA binding
HU055_RS01240	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HU055_RS01250	COG0051	transcription antitermination factor activity, RNA binding
HU055_RS01255	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HU055_RS01260	COG0088	Forms part of the polypeptide exit tunnel
HU055_RS01265	COG0089	rRNA binding
HU055_RS01270	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HU055_RS01275	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HU055_RS01280	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HU055_RS01290	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HU055_RS01295	COG0255	Belongs to the universal ribosomal protein uL29 family
HU055_RS01300	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HU055_RS01305	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HU055_RS01310	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HU055_RS01315	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HU055_RS01320	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HU055_RS01325	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HU055_RS01330	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HU055_RS01335	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HU055_RS01345	COG1841	ribosomal large subunit assembly
HU055_RS01350	COG0200	Binds to the 23S rRNA
HU055_RS01355	COG0201	protein transport
HU055_RS01360	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HU055_RS01365	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HU055_RS01370	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HU055_RS01375	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HU055_RS01380	COG0202	RNA polymerase activity
HU055_RS01385	COG0203	ribosomal protein L17
HU055_RS01395	COG0789	Transcriptional regulator
HU055_RS01400	COG3036	rescue of stalled ribosome
HU055_RS01410	COG1970	mechanosensitive ion channel activity
HU055_RS01420	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HU055_RS01420	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HU055_RS01425	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HU055_RS01430	COG0242	peptide deformylase activity
HU055_RS01435	COG0758	DNA mediated transformation
HU055_RS01440	COG2922	Belongs to the Smg family
HU055_RS01445	COG0551	DNA topoisomerase type I activity
HU055_RS01455	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HU055_RS01465	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HU055_RS01500	COG1126	abc transporter atp-binding protein
HU055_RS01505	COG0765	amino acid transport
HU055_RS01510	COG4597	amino acid ABC transporter
HU055_RS01515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HU055_RS01520	COG1560	Kdo2-lipid A biosynthetic process
HU055_RS01540	COG2264	protein methyltransferase activity
HU055_RS01545	COG4145	pantothenate transmembrane transporter activity
HU055_RS01550	COG3924	membrane
HU055_RS01555	COG0439	Biotin carboxylase
HU055_RS01560	COG0511	ligase activity, forming carbon-carbon bonds
HU055_RS01565	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HU055_RS01575	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HU055_RS01580	COG0604	alcohol dehydrogenase
HU055_RS01585	COG2200	EAL domain
HU055_RS01585	COG2199	diguanylate cyclase activity
HU055_RS01590	COG1077	Cell shape determining protein MreB Mrl
HU055_RS01595	COG1792	Involved in formation and maintenance of cell shape
HU055_RS01600	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HU055_RS01610	COG1530	ribonuclease E activity
HU055_RS01620	COG0312	modulator of DNA gyrase
HU055_RS01625	COG0583	DNA-binding transcription factor activity
HU055_RS01635	COG1566	PFAM secretion protein HlyD family protein
HU055_RS01640	COG1289	transmembrane transporter activity
HU055_RS01655	COG1438	arginine binding
HU055_RS01660	COG0039	L-malate dehydrogenase activity
HU055_RS01665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HU055_RS01670	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HU055_RS01675	COG3105	Protein conserved in bacteria
HU055_RS01680	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HU055_RS01685	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HU055_RS01690	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HU055_RS01695	COG0625	glutathione transferase activity
HU055_RS01700	COG2969	positive regulation of protein catabolic process
HU055_RS01705	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HU055_RS01710	COG0067	glutamate synthase
HU055_RS01710	COG0069	glutamate synthase activity
HU055_RS01710	COG0070	glutamate synthase
HU055_RS01715	COG0784	Response regulator, receiver
HU055_RS01715	COG2198	Histidine kinase
HU055_RS01715	COG5002	protein histidine kinase activity
HU055_RS01725	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HU055_RS01730	COG1660	Displays ATPase and GTPase activities
HU055_RS01745	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HU055_RS01750	COG1137	ATPase activity
HU055_RS01755	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HU055_RS01760	COG3117	lipopolysaccharide transmembrane transporter activity
HU055_RS01765	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HU055_RS01775	COG0530	calcium, potassium:sodium antiporter activity
HU055_RS01780	COG1127	ABC transporter
HU055_RS01785	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HU055_RS01790	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HU055_RS01795	COG2854	intermembrane phospholipid transfer
HU055_RS01800	COG3113	response to antibiotic
HU055_RS01805	COG5007	Belongs to the BolA IbaG family
HU055_RS01810	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HU055_RS01815	COG3423	Transcriptional regulator
HU055_RS01820	COG0142	geranyltranstransferase activity
HU055_RS01825	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HU055_RS01830	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HU055_RS01840	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HU055_RS01845	COG0642	Histidine kinase
HU055_RS01850	COG0745	RESPONSE REGULATOR receiver
HU055_RS01855	COG2027	D-alanyl-D-alanine carboxypeptidase
HU055_RS01865	COG1534	Rna-binding protein
HU055_RS01870	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
HU055_RS01880	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HU055_RS01885	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HU055_RS01890	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HU055_RS01905	COG0779	Required for maturation of 30S ribosomal subunits
HU055_RS01910	COG0195	Participates in both transcription termination and antitermination
HU055_RS01920	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HU055_RS01925	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HU055_RS01930	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HU055_RS01935	COG1185	polyribonucleotide nucleotidyltransferase activity
HU055_RS01950	COG0513	Belongs to the DEAD box helicase family
HU055_RS01955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HU055_RS01960	COG3153	acetyltransferase
HU055_RS01965	COG2827	Endonuclease containing a URI domain
HU055_RS01970	COG3766	membrane
HU055_RS01975	COG0602	queuosine metabolic process
HU055_RS01985	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HU055_RS01990	COG3525	Glycosyl hydrolase, family 20, catalytic domain
HU055_RS02000	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
HU055_RS02010	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HU055_RS02015	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
HU055_RS02020	COG0456	acetyltransferase
HU055_RS02035	COG2271	Major facilitator Superfamily
HU055_RS02045	COG0525	valine-tRNA ligase activity
HU055_RS02050	COG2927	DNA polymerase III (CHI subunit)
HU055_RS02055	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HU055_RS02060	COG0795	lipopolysaccharide-transporting ATPase activity
HU055_RS02065	COG0795	lipopolysaccharide-transporting ATPase activity
HU055_RS02070	COG2733	membrane
HU055_RS02075	COG0433	COG0433 Predicted ATPase
HU055_RS02090	COG0582	viral genome integration into host DNA
HU055_RS02110	COG1715	Restriction endonuclease
HU055_RS02160	COG2003	Belongs to the UPF0758 family
HU055_RS02200	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HU055_RS02205	COG3318	Belongs to the UPF0149 family
HU055_RS02205	COG3012	SEC-C Motif Domain Protein
HU055_RS02210	COG1464	Belongs to the NlpA lipoprotein family
HU055_RS02220	COG3423	Transcriptional regulator
HU055_RS02225	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HU055_RS02240	COG3663	DNA glycosylase
HU055_RS02250	COG0358	DNA primase activity
HU055_RS02255	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HU055_RS02260	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HU055_RS02265	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
HU055_RS02270	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HU055_RS02275	COG1968	undecaprenyl-diphosphatase activity
HU055_RS02280	COG0617	tRNA 3'-terminal CCA addition
HU055_RS02285	COG4991	sh3 domain protein
HU055_RS02290	COG3025	triphosphatase activity
HU055_RS02300	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
HU055_RS02300	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HU055_RS02310	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HU055_RS02315	COG3384	dioxygenase
HU055_RS02320	COG0754	glutathionylspermidine amidase activity
HU055_RS02325	COG5463	Belongs to the UPF0441 family
HU055_RS02330	COG1538	Outer membrane efflux protein
HU055_RS02335	COG0494	nUDIX hydrolase
HU055_RS02340	COG3151	Protein conserved in bacteria
HU055_RS02345	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HU055_RS02350	COG3150	esterase
HU055_RS02375	COG0167	dihydroorotate dehydrogenase activity
HU055_RS02390	COG0318	PFAM AMP-dependent synthetase and ligase
HU055_RS02390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HU055_RS02390	COG0300	oxidoreductase activity
HU055_RS02390	COG3321	synthase
HU055_RS02390	COG1028	Short-chain dehydrogenase reductase Sdr
HU055_RS02450	COG2132	Multicopper oxidase
HU055_RS02455	COG0656	L-ascorbic acid biosynthetic process
HU055_RS02460	COG2207	Transcriptional regulator
HU055_RS02465	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HU055_RS02470	COG0076	glutamate decarboxylase activity
HU055_RS02475	COG0586	Pfam SNARE associated Golgi protein
HU055_RS02480	COG0626	cystathionine gamma-synthase activity
HU055_RS02490	COG0848	biopolymer transport protein
HU055_RS02500	COG1028	Short-chain dehydrogenase reductase Sdr
HU055_RS02530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HU055_RS02555	COG0671	phosphoesterase, PA-phosphatase related
HU055_RS02565	COG1528	Iron-storage protein
HU055_RS02575	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HU055_RS02590	COG2723	6-phospho-beta-galactosidase activity
HU055_RS02595	COG2723	6-phospho-beta-galactosidase activity
HU055_RS02600	COG1447	Phosphotransferase system cellobiose-specific component IIA
HU055_RS02605	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HU055_RS02615	COG1609	Transcriptional regulator
HU055_RS02640	COG1522	sequence-specific DNA binding
HU055_RS02660	COG3275	phosphorelay sensor kinase activity
HU055_RS02670	COG2879	small protein
HU055_RS02675	COG1966	Carbon starvation protein
HU055_RS02705	COG1834	amidinotransferase
HU055_RS02710	COG0151	Belongs to the GarS family
HU055_RS02715	COG0151	Belongs to the GarS family
HU055_RS02730	COG4792	protein secretion
HU055_RS02740	COG4794	Type iii secretion
HU055_RS02765	COG1157	protein secretion by the type III secretion system
HU055_RS02795	COG2197	response regulator
HU055_RS02885	COG5297	Belongs to the glycosyl hydrolase family 6
HU055_RS02900	COG0583	DNA-binding transcription factor activity
HU055_RS02920	COG3179	chitinase
HU055_RS02985	COG1982	Orn Lys Arg decarboxylase major
HU055_RS02995	COG0741	lytic transglycosylase activity
HU055_RS03000	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
HU055_RS03015	COG3171	Protein conserved in bacteria
HU055_RS03025	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HU055_RS03030	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HU055_RS03035	COG0762	integral membrane protein
HU055_RS03040	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HU055_RS03045	COG2805	Type II/IV secretion system protein
HU055_RS03060	COG4232	protein-disulfide reductase activity
HU055_RS03070	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HU055_RS03075	COG1678	Uncharacterized ACR, COG1678
HU055_RS03085	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HU055_RS03090	COG2356	endonuclease I
HU055_RS03095	COG3091	SprT-like family
HU055_RS03100	COG2814	Major facilitator Superfamily
HU055_RS03105	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HU055_RS03110	COG1166	arginine decarboxylase activity
HU055_RS03150	COG0501	Belongs to the peptidase M48B family
HU055_RS03155	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HU055_RS03160	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HU055_RS03165	COG0126	phosphoglycerate kinase activity
HU055_RS03170	COG0191	fructose-bisphosphate aldolase activity
HU055_RS03175	COG0668	transmembrane transport
HU055_RS03190	COG2072	flavoprotein involved in K transport
HU055_RS03205	COG0673	inositol 2-dehydrogenase activity
HU055_RS03215	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HU055_RS03225	COG0583	DNA-binding transcription factor activity
HU055_RS03230	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HU055_RS03240	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HU055_RS03245	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HU055_RS03255	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HU055_RS03260	COG3079	Belongs to the UPF0149 family
HU055_RS03265	COG0006	proline dipeptidase activity
HU055_RS03270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HU055_RS03275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HU055_RS03280	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HU055_RS03285	COG0509	glycine decarboxylation via glycine cleavage system
HU055_RS03290	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HU055_RS03290	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HU055_RS03295	COG1028	Short-chain dehydrogenase reductase Sdr
HU055_RS03305	COG1272	protein, Hemolysin III
HU055_RS03310	COG0354	folic acid binding
HU055_RS03315	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HU055_RS03325	COG0716	FMN binding
HU055_RS03330	COG0697	spore germination
HU055_RS03340	COG4974	Belongs to the 'phage' integrase family
HU055_RS03350	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HU055_RS03360	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HU055_RS03370	COG2814	Major facilitator Superfamily
HU055_RS03375	COG0583	DNA-binding transcription factor activity
HU055_RS03385	COG1609	Transcriptional regulator
HU055_RS03400	COG3210	domain, Protein
HU055_RS03415	COG3210	domain, Protein
HU055_RS03430	COG3210	domain, Protein
HU055_RS03445	COG3210	domain, Protein
HU055_RS03460	COG3210	domain, Protein
HU055_RS03465	COG2831	hemolysin activation secretion protein
HU055_RS03480	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HU055_RS03505	COG0204	Acyl-transferase
HU055_RS03505	COG0318	PFAM AMP-dependent synthetase and ligase
HU055_RS03515	COG0667	Aldo Keto reductase
HU055_RS03525	COG0861	Integral membrane protein TerC family
HU055_RS03530	COG3066	DNA modification
HU055_RS03535	COG1051	belongs to the nudix hydrolase family
HU055_RS03545	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HU055_RS03550	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HU055_RS03555	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HU055_RS03565	COG4795	General secretion pathway protein
HU055_RS03580	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HU055_RS03595	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HU055_RS03605	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HU055_RS03605	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HU055_RS03610	COG0860	N-Acetylmuramoyl-L-alanine amidase
HU055_RS03630	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HU055_RS03635	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HU055_RS03640	COG2166	iron-sulfur cluster assembly
HU055_RS03645	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HU055_RS03655	COG0583	DNA-binding transcription factor activity
HU055_RS03660	COG2363	Small membrane protein
HU055_RS03665	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
HU055_RS03670	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HU055_RS03675	COG1611	Belongs to the LOG family
HU055_RS03680	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HU055_RS03680	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HU055_RS03690	COG3098	single-species biofilm formation
HU055_RS03695	COG0564	pseudouridine synthase activity
HU055_RS03700	COG0716	FMN binding
HU055_RS03705	COG1929	Belongs to the glycerate kinase type-1 family
HU055_RS03715	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HU055_RS03720	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HU055_RS03725	COG3956	TIGRFAM MazG family protein
HU055_RS03730	COG0504	CTP synthase activity
HU055_RS03735	COG0148	phosphopyruvate hydratase activity
HU055_RS03740	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HU055_RS03740	COG2755	lipolytic protein G-D-S-L family
HU055_RS03745	COG0602	queuosine metabolic process
HU055_RS03750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HU055_RS03755	COG1126	abc transporter atp-binding protein
HU055_RS03760	COG0765	amino acid transport
HU055_RS03770	COG0720	synthase
HU055_RS03780	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HU055_RS03785	COG0175	sulfate reduction
HU055_RS03795	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HU055_RS03795	COG1648	precorrin-2 dehydrogenase activity
HU055_RS03800	COG0175	sulfate reduction
HU055_RS03805	COG2895	sulfate adenylyltransferase (ATP) activity
HU055_RS03810	COG0529	Catalyzes the synthesis of activated sulfate
HU055_RS03820	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HU055_RS03825	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
HU055_RS03830	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
HU055_RS03835	COG0585	pseudouridine synthase activity
HU055_RS03840	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HU055_RS03845	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HU055_RS03850	COG4942	peptidase
HU055_RS03850	COG1388	LysM domain
HU055_RS03855	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HU055_RS03860	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HU055_RS04000	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HU055_RS04020	COG5455	response to cobalt ion
HU055_RS04025	COG2951	lytic endotransglycosylase activity
HU055_RS04030	COG1546	Belongs to the CinA family
HU055_RS04035	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HU055_RS04050	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HU055_RS04075	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HU055_RS04080	COG1238	metal cluster binding
HU055_RS04085	COG2918	glutathione biosynthetic process
HU055_RS04095	COG4536	flavin adenine dinucleotide binding
HU055_RS04100	COG4137	Cytochrome C assembly protein
HU055_RS04105	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HU055_RS04110	COG0228	four-way junction DNA binding
HU055_RS04125	COG0335	large ribosomal subunit rRNA binding
HU055_RS04150	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HU055_RS04155	COG0287	Prephenate dehydrogenase
HU055_RS04155	COG1605	Chorismate mutase
HU055_RS04160	COG1605	Chorismate mutase
HU055_RS04160	COG0077	Prephenate dehydratase
HU055_RS04165	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HU055_RS04170	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HU055_RS04175	COG0564	pseudouridine synthase activity
HU055_RS04185	COG0542	response to heat
HU055_RS04220	COG3021	interspecies interaction between organisms
HU055_RS04230	COG1388	LysM domain
HU055_RS04230	COG0741	lytic transglycosylase activity
HU055_RS04235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HU055_RS04245	COG0328	RNA-DNA hybrid ribonuclease activity
HU055_RS04250	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HU055_RS04260	COG1953	Uracil, thiamine, allantoin
HU055_RS04285	COG2189	Belongs to the N(4) N(6)-methyltransferase family
HU055_RS04290	COG1715	Restriction endonuclease
HU055_RS04330	COG0765	amino acid transport
HU055_RS04345	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HU055_RS04360	COG2351	hydroxyisourate hydrolase activity
HU055_RS04370	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HU055_RS04375	COG0436	Aminotransferase
HU055_RS04395	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
HU055_RS04400	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HU055_RS04410	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HU055_RS04415	COG1960	acyl-CoA dehydrogenase activity
HU055_RS04420	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
HU055_RS04425	COG0121	glutamine amidotransferase
HU055_RS04430	COG3034	peptidoglycan biosynthetic process
HU055_RS04440	COG2195	Cleaves the N-terminal amino acid of tripeptides
HU055_RS04445	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
HU055_RS04465	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HU055_RS04470	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HU055_RS04475	COG2832	Protein of unknown function (DUF454)
HU055_RS04480	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HU055_RS04535	COG4608	Belongs to the ABC transporter superfamily
HU055_RS04540	COG0444	Belongs to the ABC transporter superfamily
HU055_RS04550	COG0601	transmembrane transport
HU055_RS04555	COG0747	negative chemotaxis
HU055_RS04575	COG1278	Cold shock
HU055_RS04580	COG3250	beta-galactosidase activity
HU055_RS04595	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HU055_RS04600	COG1671	Belongs to the UPF0178 family
HU055_RS04605	COG3416	Protein conserved in bacteria
HU055_RS04610	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HU055_RS04635	COG4126	flavin adenine dinucleotide binding
HU055_RS04640	COG3123	guanosine phosphorylase activity
HU055_RS04645	COG2974	May be involved in recombination
HU055_RS04685	COG0419	ATPase involved in DNA repair
HU055_RS04690	COG0420	3'-5' exonuclease activity
HU055_RS04700	COG5002	protein histidine kinase activity
HU055_RS04710	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HU055_RS04725	COG0450	alkyl hydroperoxide reductase
HU055_RS04730	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
HU055_RS04735	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HU055_RS04750	COG2246	polysaccharide biosynthetic process
HU055_RS04755	COG0343	queuine tRNA-ribosyltransferase activity
HU055_RS04760	COG1862	Preprotein translocase
HU055_RS04765	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HU055_RS04770	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HU055_RS04780	COG1652	LysM domain
HU055_RS04785	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HU055_RS04790	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HU055_RS04790	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HU055_RS04795	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
HU055_RS04800	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HU055_RS04805	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HU055_RS04810	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HU055_RS04815	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HU055_RS04820	COG0142	geranyltranstransferase activity
HU055_RS04825	COG1722	exodeoxyribonuclease VII activity
HU055_RS04830	COG0301	tRNA thio-modification
HU055_RS04830	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HU055_RS04840	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HU055_RS04845	COG1666	GTP binding
HU055_RS04850	COG2814	Major facilitator Superfamily
HU055_RS04855	COG0109	protoheme IX farnesyltransferase activity
HU055_RS04860	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HU055_RS04865	COG1845	cytochrome c oxidase, subunit III
HU055_RS04870	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HU055_RS04875	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HU055_RS04880	COG2223	nitrite transmembrane transporter activity
HU055_RS04885	COG3056	Lipoprotein
HU055_RS04890	COG0271	Belongs to the BolA IbaG family
HU055_RS04895	COG0544	peptidyl-prolyl cis-trans isomerase activity
HU055_RS04910	COG0740	serine-type endopeptidase activity
HU055_RS04925	COG0776	regulation of translation
HU055_RS04930	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HU055_RS04935	COG1555	photosystem II stabilization
HU055_RS04940	COG0824	Thioesterase
HU055_RS04945	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HU055_RS04955	COG1522	sequence-specific DNA binding
HU055_RS04960	COG1132	(ABC) transporter
HU055_RS04965	COG1132	(ABC) transporter
HU055_RS04970	COG0347	Belongs to the P(II) protein family
HU055_RS04975	COG0004	ammonium transporteR
HU055_RS04980	COG1946	Acyl-CoA thioesterase
HU055_RS04985	COG3126	Type III secretion system lipoprotein chaperone (YscW)
HU055_RS04990	COG3695	enzyme binding
HU055_RS05015	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HU055_RS05020	COG0254	rRNA binding
HU055_RS05025	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HU055_RS05030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HU055_RS05035	COG1309	transcriptional regulator
HU055_RS05055	COG2832	Protein of unknown function (DUF454)
HU055_RS05060	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HU055_RS05070	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HU055_RS05075	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HU055_RS05080	COG0326	Molecular chaperone. Has ATPase activity
HU055_RS05085	COG0583	DNA-binding transcription factor activity
HU055_RS05110	COG0563	adenylate kinase activity
HU055_RS05115	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HU055_RS05120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HU055_RS05130	COG4651	solute:proton antiporter activity
HU055_RS05130	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HU055_RS05135	COG2223	nitrite transmembrane transporter activity
HU055_RS05140	COG0737	Belongs to the 5'-nucleotidase family
HU055_RS05155	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HU055_RS05160	COG3735	TraB family
HU055_RS05165	COG2217	Heavy metal translocating P-type atpase
HU055_RS05175	COG1585	Membrane protein implicated in regulation of membrane protease activity
HU055_RS05180	COG0330	HflC and HflK could
HU055_RS05185	COG3118	belongs to the thioredoxin family
HU055_RS05190	COG0300	oxidoreductase activity
HU055_RS05215	COG2755	lipolytic protein G-D-S-L family
HU055_RS05220	COG4181	ATPase activity
HU055_RS05225	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HU055_RS05230	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HU055_RS05235	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HU055_RS05245	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HU055_RS05250	COG0215	cysteine-tRNA ligase activity
HU055_RS05255	COG1064	alcohol dehydrogenase
HU055_RS05260	COG2501	S4 domain
HU055_RS05265	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HU055_RS05275	COG0582	viral genome integration into host DNA
HU055_RS05300	COG1764	response to oxidative stress
HU055_RS05315	COG1410	methionine synthase
HU055_RS05315	COG0646	methionine synthase
HU055_RS05335	COG4172	Belongs to the ABC transporter superfamily
HU055_RS05350	COG4772	TonB-dependent receptor
HU055_RS05355	COG4993	Dehydrogenase
HU055_RS05365	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HU055_RS05370	COG0463	Glycosyl transferase, family 2
HU055_RS05375	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HU055_RS05375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HU055_RS05380	COG0726	polysaccharide deacetylase
HU055_RS05385	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HU055_RS05390	COG2076	Multidrug Resistance protein
HU055_RS05395	COG2076	Multidrug Resistance protein
HU055_RS05405	COG1294	oxidase, subunit
HU055_RS05410	COG1271	oxidase subunit
HU055_RS05425	COG1349	DNA-binding transcription factor activity
HU055_RS05430	COG2084	Dehydrogenase
HU055_RS05435	COG3395	kinase activity
HU055_RS05440	COG0235	Class ii aldolase
HU055_RS05445	COG3622	Belongs to the hyi family
HU055_RS05450	COG2610	gluconate transmembrane transporter activity
HU055_RS05455	COG2610	gluconate transmembrane transporter activity
HU055_RS05470	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HU055_RS05475	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HU055_RS05480	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HU055_RS05485	COG0321	lipoyl(octanoyl) transferase activity
HU055_RS05490	COG2921	Belongs to the UPF0250 family
HU055_RS05495	COG1686	Belongs to the peptidase S11 family
HU055_RS05500	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HU055_RS05505	COG0772	Belongs to the SEDS family
HU055_RS05510	COG0768	penicillin binding
HU055_RS05515	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HU055_RS05520	COG0799	negative regulation of ribosome biogenesis
HU055_RS05530	COG1466	dna polymerase III delta subunit
HU055_RS05535	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
HU055_RS05540	COG0495	leucyl-tRNA aminoacylation
HU055_RS05545	COG2888	peptidyl-tyrosine sulfation
HU055_RS05550	COG1126	abc transporter atp-binding protein
HU055_RS05555	COG0765	amino acid transport
HU055_RS05560	COG0765	amino acid transport
HU055_RS05570	COG0815	Transfers the fatty acyl group on membrane lipoproteins
HU055_RS05575	COG4535	Mg2 and Co2 transporter CorC
HU055_RS05580	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HU055_RS05585	COG1702	phosphate starvation-inducible protein PhoH
HU055_RS05590	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HU055_RS05595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HU055_RS05630	COG0367	asparagine synthase
HU055_RS05635	COG0647	UMP catabolic process
HU055_RS05640	COG1846	Transcriptional regulator
HU055_RS05640	COG1940	carbohydrate kinase activity
HU055_RS05645	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HU055_RS05650	COG0363	glucosamine-6-phosphate deaminase activity
HU055_RS05660	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HU055_RS05665	COG0814	amino acid
HU055_RS05670	COG0735	belongs to the Fur family
HU055_RS05685	COG0596	Alpha beta hydrolase
HU055_RS05690	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
HU055_RS05695	COG0033	Phosphoglucomutase
HU055_RS05700	COG0745	RESPONSE REGULATOR receiver
HU055_RS05710	COG3272	Protein of unknown function (DUF1722)
HU055_RS05715	COG0415	Belongs to the DNA photolyase family
HU055_RS05725	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HU055_RS05730	COG1984	allophanate hydrolase subunit 2
HU055_RS05735	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
HU055_RS05740	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HU055_RS05750	COG0372	Belongs to the citrate synthase family
HU055_RS05755	COG2009	succinate dehydrogenase
HU055_RS05760	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HU055_RS05765	COG1053	succinate dehydrogenase
HU055_RS05770	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HU055_RS05775	COG0567	Dehydrogenase, E1 component
HU055_RS05780	COG0508	dehydrogenase complex catalyzes the overall conversion of
HU055_RS05785	COG0045	succinate-CoA ligase (ADP-forming) activity
HU055_RS05790	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HU055_RS05795	COG0824	Thioesterase
HU055_RS05800	COG0811	peptide transport
HU055_RS05805	COG0848	biopolymer transport protein
HU055_RS05815	COG0823	Involved in the tonB-independent uptake of proteins
HU055_RS05820	COG2885	chlorophyll binding
HU055_RS05825	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HU055_RS05890	COG1230	cation diffusion facilitator family transporter
HU055_RS05900	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HU055_RS05920	COG0588	phosphoglycerate mutase activity
HU055_RS05925	COG2017	converts alpha-aldose to the beta-anomer
HU055_RS05930	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HU055_RS05940	COG1119	ATPase activity
HU055_RS05945	COG3585	molybdate ion transport
HU055_RS05945	COG2005	Transcriptional regulator
HU055_RS05955	COG0725	ABC transporter, periplasmic molybdate-binding protein
HU055_RS05960	COG4149	molybdate abc transporter
HU055_RS05970	COG0561	phosphatase activity
HU055_RS05975	COG2706	6-phosphogluconolactonase activity
HU055_RS05980	COG1881	PFAM PEBP family protein
HU055_RS05985	COG2130	NADP-dependent
HU055_RS05995	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HU055_RS06000	COG0156	8-amino-7-oxononanoate synthase activity
HU055_RS06010	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HU055_RS06020	COG0556	nucleotide-excision repair
HU055_RS06035	COG0521	Mo-molybdopterin cofactor biosynthetic process
HU055_RS06040	COG0315	cyclic pyranopterin monophosphate synthase activity
HU055_RS06045	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HU055_RS06060	COG0670	Belongs to the BI1 family
HU055_RS06070	COG0513	Belongs to the DEAD box helicase family
HU055_RS06075	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HU055_RS06080	COG1376	ErfK ybiS ycfS ynhG family protein
HU055_RS06085	COG3387	PFAM Glycoside hydrolase 15-related
HU055_RS06090	COG0586	Pfam SNARE associated Golgi protein
HU055_RS06100	COG1686	Belongs to the peptidase S11 family
HU055_RS06105	COG3264	Mechanosensitive ion channel
HU055_RS06105	COG1511	domain protein
HU055_RS06115	COG0277	FAD linked oxidase domain protein
HU055_RS06130	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
HU055_RS06150	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HU055_RS06165	COG4221	oxidoreductase activity
HU055_RS06175	COG0789	Transcriptional regulator
HU055_RS06195	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HU055_RS06200	COG1473	amidohydrolase
HU055_RS06205	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HU055_RS06210	COG2986	histidine ammonia-lyase
HU055_RS06225	COG0402	S-adenosylhomocysteine deaminase activity
HU055_RS06230	COG1228	amidohydrolase
HU055_RS06240	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
HU055_RS06245	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HU055_RS06260	COG0641	radical SAM
HU055_RS06270	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
HU055_RS06275	COG0668	transmembrane transport
HU055_RS06285	COG1126	abc transporter atp-binding protein
HU055_RS06290	COG0765	amino acid transport
HU055_RS06295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HU055_RS06300	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HU055_RS06305	COG0783	Belongs to the Dps family
HU055_RS06315	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HU055_RS06320	COG1321	iron dependent repressor
HU055_RS06325	COG1566	PFAM secretion protein HlyD family protein
HU055_RS06330	COG2814	Major facilitator Superfamily
HU055_RS06345	COG2814	Major facilitator Superfamily
HU055_RS06350	COG0488	(ABC) transporter
HU055_RS06360	COG0303	'Molybdopterin
HU055_RS06370	COG4172	Belongs to the ABC transporter superfamily
HU055_RS06390	COG1686	Belongs to the peptidase S11 family
HU055_RS06395	COG0814	amino acid
HU055_RS06430	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HU055_RS06435	COG3842	ATPase activity
HU055_RS06445	COG1177	transmembrane transport
HU055_RS06455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HU055_RS06460	COG4160	amino acid transport
HU055_RS06465	COG4215	(ABC) transporter
HU055_RS06470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HU055_RS06475	COG1126	abc transporter atp-binding protein
HU055_RS06485	COG0393	Putative heavy-metal-binding
HU055_RS06490	COG3023	N-Acetylmuramoyl-L-alanine amidase
HU055_RS06500	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
HU055_RS06505	COG0028	Belongs to the TPP enzyme family
HU055_RS06510	COG3593	DNA synthesis involved in DNA repair
HU055_RS06515	COG1278	Cold shock
HU055_RS06525	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HU055_RS06530	COG0542	response to heat
HU055_RS06535	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HU055_RS06540	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
HU055_RS06545	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HU055_RS06550	COG4988	ABC transporter
HU055_RS06555	COG0492	ferredoxin-NADP+ reductase activity
HU055_RS06565	COG1674	ftsk spoiiie
HU055_RS06565	COG3107	peptidoglycan biosynthetic process
HU055_RS06570	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HU055_RS06575	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HU055_RS06580	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HU055_RS06585	COG0477	Major facilitator Superfamily
HU055_RS06595	COG1944	ATP diphosphatase activity
HU055_RS06600	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HU055_RS06605	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HU055_RS06610	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
HU055_RS06615	COG0539	negative regulation of cytoplasmic translation
HU055_RS06620	COG0776	regulation of translation
HU055_RS06625	COG0658	competence protein
HU055_RS06625	COG2333	competence protein COMEC
HU055_RS06635	COG1663	tetraacyldisaccharide 4'-kinase activity
HU055_RS06640	COG2835	tetraacyldisaccharide 4'-kinase activity
HU055_RS06645	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
HU055_RS06650	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HU055_RS06655	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HU055_RS06660	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
HU055_RS06665	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
HU055_RS06670	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
HU055_RS06675	COG2989	Protein conserved in bacteria
HU055_RS06680	COG3108	Peptidase M15
HU055_RS06685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HU055_RS06690	COG1448	Aminotransferase
HU055_RS06700	COG0017	Asparaginyl-tRNA synthetase
HU055_RS06705	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HU055_RS06710	COG0308	aminopeptidase N
HU055_RS06720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HU055_RS06730	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HU055_RS06735	COG0431	NADPH-dependent FMN reductase
HU055_RS06740	COG0167	dihydroorotate dehydrogenase activity
HU055_RS06750	COG0633	Ferredoxin
HU055_RS06750	COG3217	Mosc domain protein beta barrel domain protein
HU055_RS06755	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HU055_RS06755	COG0116	Belongs to the methyltransferase superfamily
HU055_RS06760	COG0488	(ABC) transporter
HU055_RS06765	COG2995	paraquat-inducible protein a
HU055_RS06770	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HU055_RS06770	COG3008	intermembrane lipid transfer
HU055_RS06775	COG3009	Protein conserved in bacteria
HU055_RS06780	COG3130	regulation of translation
HU055_RS06785	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HU055_RS06790	COG1067	ATP-dependent peptidase activity
HU055_RS06795	COG3120	sequence-specific DNA binding
HU055_RS06800	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HU055_RS06800	COG2885	chlorophyll binding
HU055_RS06810	COG3070	regulator of competence-specific genes
HU055_RS06815	COG1289	transmembrane transporter activity
HU055_RS06820	COG3304	Inner membrane component domain
HU055_RS06825	COG0210	DNA helicase
HU055_RS06830	COG1803	Methylglyoxal synthase
HU055_RS06840	COG3785	DNA binding
HU055_RS06845	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HU055_RS06855	COG2920	part of a sulfur-relay system
HU055_RS06860	COG0670	Belongs to the BI1 family
HU055_RS06885	COG1012	belongs to the aldehyde dehydrogenase family
HU055_RS06900	COG1309	transcriptional regulator
HU055_RS06910	COG1113	amino acid transport
HU055_RS06915	COG2197	response regulator
HU055_RS06925	COG3136	membrane protein required for alginate biosynthesis
HU055_RS06935	COG2197	response regulator
HU055_RS06940	COG0322	excinuclease ABC activity
HU055_RS06945	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HU055_RS06970	COG1846	Transcriptional regulator
HU055_RS07000	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HU055_RS07020	COG5645	(Lipo)protein
HU055_RS07030	COG1560	Kdo2-lipid A biosynthetic process
HU055_RS07045	COG3038	cytochrome b561
HU055_RS07065	COG0418	dihydroorotase activity
HU055_RS07075	COG2999	glutathione oxidoreductase activity
HU055_RS07080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HU055_RS07095	COG3418	PFAM FlgN family protein
HU055_RS07110	COG1815	bacterial-type flagellum-dependent cell motility
HU055_RS07115	COG1558	bacterial-type flagellum-dependent cell motility
HU055_RS07120	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HU055_RS07125	COG1749	Flagellar hook protein flgE
HU055_RS07155	COG1256	bacterial-type flagellum assembly
HU055_RS07160	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HU055_RS07165	COG1530	ribonuclease E activity
HU055_RS07165	COG1530	ribonuclease E activity
HU055_RS07170	COG0564	pseudouridine synthase activity
HU055_RS07175	COG0424	maF-like protein
HU055_RS07180	COG1399	metal-binding, possibly nucleic acid-binding protein
HU055_RS07185	COG0333	Belongs to the bacterial ribosomal protein bL32 family
HU055_RS07190	COG0416	fatty acid biosynthetic process
HU055_RS07195	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HU055_RS07200	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HU055_RS07210	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HU055_RS07215	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HU055_RS07220	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HU055_RS07225	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HU055_RS07230	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HU055_RS07235	COG0470	DNA polymerase III
HU055_RS07240	COG0084	hydrolase, TatD family'
HU055_RS07245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HU055_RS07245	COG1263	PTS System
HU055_RS07250	COG0537	adenosine 5'-monophosphoramidase activity
HU055_RS07260	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
HU055_RS07270	COG1472	Belongs to the glycosyl hydrolase 3 family
HU055_RS07280	COG1252	NADH dehydrogenase
HU055_RS07285	COG3134	Outer membrane lipoprotein
HU055_RS07290	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HU055_RS07295	COG1215	transferase activity, transferring glycosyl groups
HU055_RS07345	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HU055_RS07350	COG1580	Controls the rotational direction of flagella during chemotaxis
HU055_RS07370	COG1317	bacterial-type flagellum organization
HU055_RS07375	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HU055_RS07385	COG1677	Flagellar hook-basal body complex protein FliE
HU055_RS07390	COG0784	Response regulator, receiver
HU055_RS07390	COG0835	chemotaxis
HU055_RS07410	COG2199	diguanylate cyclase activity
HU055_RS07415	COG4591	ABC-type transport system involved in lipoprotein release permease component
HU055_RS07425	COG4591	ABC-type transport system involved in lipoprotein release permease component
HU055_RS07430	COG1940	carbohydrate kinase activity
HU055_RS07440	COG3135	benzoate transporter
HU055_RS07445	COG1396	sequence-specific DNA binding
HU055_RS07450	COG2850	peptidyl-arginine hydroxylation
HU055_RS07460	COG0745	RESPONSE REGULATOR receiver
HU055_RS07465	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HU055_RS07470	COG2915	High frequency lysogenization protein hflD homolog
HU055_RS07490	COG0538	isocitrate dehydrogenase activity
HU055_RS07530	COG1619	proteins homologs of microcin C7 resistance protein MccF
HU055_RS07540	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
HU055_RS07545	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
HU055_RS07550	COG2261	transglycosylase associated protein
HU055_RS07560	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HU055_RS07575	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HU055_RS07575	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HU055_RS07595	COG4565	transcriptional regulatory protein
HU055_RS07600	COG3290	protein histidine kinase activity
HU055_RS07750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HU055_RS07760	COG0012	GTP binding
HU055_RS07765	COG0659	secondary active sulfate transmembrane transporter activity
HU055_RS07775	COG0193	aminoacyl-tRNA hydrolase activity
HU055_RS07790	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HU055_RS07795	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
HU055_RS07800	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HU055_RS07805	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HU055_RS07810	COG2890	protein-(glutamine-N5) methyltransferase activity
HU055_RS07820	COG2912	Transglutaminase-like superfamily
HU055_RS07825	COG2877	3-deoxy-8-phosphooctulonate synthase activity
HU055_RS07830	COG3187	Heat shock protein
HU055_RS07835	COG0387	Pfam Sodium calcium exchanger
HU055_RS07865	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
HU055_RS07895	COG4932	domain protein
HU055_RS07900	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HU055_RS07915	COG1012	belongs to the aldehyde dehydrogenase family
HU055_RS07920	COG3724	N-succinylarginine dihydrolase activity
HU055_RS07925	COG2988	succinylglutamate desuccinylase activity
HU055_RS07930	COG3678	ATP-independent chaperone mediated protein folding
HU055_RS07935	COG0322	excinuclease ABC activity
HU055_RS07940	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HU055_RS07945	COG2814	Major facilitator Superfamily
HU055_RS07950	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HU055_RS07965	COG1988	membrane-bound metal-dependent
HU055_RS07975	COG3001	Fructosamine kinase
HU055_RS07985	COG3137	Salt-induced outer membrane protein
HU055_RS07990	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HU055_RS08000	COG0291	Belongs to the bacterial ribosomal protein bL35 family
HU055_RS08005	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HU055_RS08015	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HU055_RS08025	COG0776	regulation of translation
HU055_RS08035	COG0386	Belongs to the glutathione peroxidase family
HU055_RS08040	COG0791	NLP P60 protein
HU055_RS08050	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
HU055_RS08055	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
HU055_RS08060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HU055_RS08065	COG4558	Periplasmic binding protein
HU055_RS08070	COG3720	iron ion transport
HU055_RS08080	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
HU055_RS08085	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HU055_RS08085	COG0574	Belongs to the PEP-utilizing enzyme family
HU055_RS08095	COG0628	permease
HU055_RS08110	COG0316	Belongs to the HesB IscA family
HU055_RS08115	COG0719	Fe-S assembly protein
HU055_RS08120	COG0396	ATPase activity
HU055_RS08125	COG0719	Fe-S assembly protein
HU055_RS08135	COG2166	iron-sulfur cluster assembly
HU055_RS08145	COG0469	pyruvate kinase activity
HU055_RS08165	COG0307	riboflavin synthase, alpha
HU055_RS08170	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HU055_RS08175	COG2814	Major facilitator Superfamily
HU055_RS08180	COG0583	DNA-binding transcription factor activity
HU055_RS08185	COG1609	Transcriptional regulator
HU055_RS08190	COG0791	NLP P60 protein
HU055_RS08195	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HU055_RS08205	COG0346	lactoylglutathione lyase activity
HU055_RS08210	COG1902	pentaerythritol trinitrate reductase activity
HU055_RS08220	COG2194	sulfuric ester hydrolase activity
HU055_RS08240	COG3313	Fe-S protein
HU055_RS08260	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
HU055_RS08265	COG0259	pyridoxamine-phosphate oxidase activity
HU055_RS08270	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HU055_RS08275	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
HU055_RS08285	COG0625	glutathione transferase activity
HU055_RS08295	COG1309	transcriptional regulator
HU055_RS08310	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HU055_RS08315	COG4660	Part of a membrane complex involved in electron transport
HU055_RS08320	COG4659	FMN binding
HU055_RS08325	COG4658	electron transport chain
HU055_RS08330	COG4656	Part of a membrane complex involved in electron transport
HU055_RS08335	COG2878	Part of a membrane complex involved in electron transport
HU055_RS08340	COG4657	Part of a membrane complex involved in electron transport
HU055_RS08350	COG2160	L-arabinose isomerase activity
HU055_RS08355	COG1069	ribulokinase activity
HU055_RS08360	COG1879	ABC-type sugar transport system periplasmic component
HU055_RS08370	COG1172	Belongs to the binding-protein-dependent transport system permease family
HU055_RS08380	COG0673	inositol 2-dehydrogenase activity
HU055_RS08385	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HU055_RS08390	COG5339	Protein conserved in bacteria
HU055_RS08415	COG0583	DNA-binding transcription factor activity
HU055_RS08420	COG1940	carbohydrate kinase activity
HU055_RS08430	COG0477	Major facilitator Superfamily
HU055_RS08445	COG4221	oxidoreductase activity
HU055_RS08450	COG0402	S-adenosylhomocysteine deaminase activity
HU055_RS08455	COG0339	signal peptide processing
HU055_RS08470	COG2707	UPF0756 membrane protein
HU055_RS08480	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HU055_RS08485	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HU055_RS08495	COG1629	transport
HU055_RS08495	COG4771	TonB-dependent receptor
HU055_RS08495	COG1629	transport
HU055_RS08495	COG4771	TonB-dependent receptor
HU055_RS08510	COG1309	transcriptional regulator
HU055_RS08560	COG0840	transmembrane signaling receptor activity
HU055_RS08600	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HU055_RS08620	COG4290	ribonuclease
HU055_RS08635	COG2207	Transcriptional regulator
HU055_RS08635	COG3708	Transcriptional regulator
HU055_RS08645	COG2814	Major facilitator Superfamily
HU055_RS08675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HU055_RS08685	COG0747	negative chemotaxis
HU055_RS08690	COG2195	Cleaves the N-terminal amino acid of tripeptides
HU055_RS08710	COG2814	Major facilitator Superfamily
HU055_RS08730	COG2840	Smr protein MutS2
HU055_RS08755	COG3182	Iron-regulated membrane protein
HU055_RS08770	COG0531	amino acid
HU055_RS08780	COG0745	RESPONSE REGULATOR receiver
HU055_RS08835	COG0582	viral genome integration into host DNA
HU055_RS08840	COG2205	protein histidine kinase activity
HU055_RS08845	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HU055_RS08855	COG3591	Belongs to the peptidase S1B family
HU055_RS08860	COG3023	N-Acetylmuramoyl-L-alanine amidase
HU055_RS08865	COG1643	Atp-dependent helicase
HU055_RS08870	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HU055_RS08875	COG1028	Short-chain dehydrogenase reductase Sdr
HU055_RS08880	COG3784	Protein of unknown function (DUF1318)
HU055_RS08890	COG2911	Protein conserved in bacteria
HU055_RS08895	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HU055_RS08910	COG0513	Belongs to the DEAD box helicase family
HU055_RS08920	COG0037	tRNA processing
HU055_RS08925	COG0366	Alpha amylase catalytic
HU055_RS08935	COG3539	Fimbrial protein
HU055_RS08940	COG3121	Chaperone
HU055_RS08945	COG3188	usher protein
HU055_RS08965	COG4166	transmembrane transport
HU055_RS08970	COG4948	Mandelate Racemase Muconate Lactonizing
HU055_RS08985	COG3768	UPF0283 membrane protein
HU055_RS08990	COG3106	COG3106 Predicted ATPase
HU055_RS09000	COG1983	PspC domain protein
HU055_RS09010	COG1842	Phage shock protein A
HU055_RS09015	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HU055_RS09025	COG4168	peptide transport system, permease
HU055_RS09030	COG4171	peptide transport system, permease
HU055_RS09035	COG4172	Belongs to the ABC transporter superfamily
HU055_RS09040	COG4172	Belongs to the ABC transporter superfamily
HU055_RS09050	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HU055_RS09050	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HU055_RS09085	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
HU055_RS09090	COG0235	Class ii aldolase
HU055_RS09105	COG0023	Translation Initiation Factor
HU055_RS09110	COG0284	orotidine-5'-phosphate decarboxylase activity
HU055_RS09115	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HU055_RS09120	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
HU055_RS09125	COG0671	phosphoesterase, PA-phosphatase related
HU055_RS09135	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HU055_RS09160	COG0616	signal peptide processing
HU055_RS09165	COG1028	Short-chain dehydrogenase reductase Sdr
HU055_RS09175	COG0009	L-threonylcarbamoyladenylate synthase
HU055_RS09190	COG0512	Glutamine amidotransferase of anthranilate synthase
HU055_RS09190	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HU055_RS09195	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HU055_RS09205	COG0133	tryptophan synthase activity
HU055_RS09210	COG0159	tryptophan synthase activity
HU055_RS09220	COG3047	cAMP biosynthetic process
HU055_RS09230	COG2917	probably involved in intracellular septation
HU055_RS09245	COG2350	Protein conserved in bacteria
HU055_RS09255	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HU055_RS09260	COG3099	Belongs to the UPF0263 family
HU055_RS09270	COG0444	Belongs to the ABC transporter superfamily
HU055_RS09275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HU055_RS09280	COG0601	transmembrane transport
HU055_RS09290	COG4166	transmembrane transport
HU055_RS09295	COG2095	MarC family integral membrane protein
HU055_RS09310	COG3384	dioxygenase
HU055_RS09320	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HU055_RS09325	COG0583	DNA-binding transcription factor activity
HU055_RS09330	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HU055_RS09335	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HU055_RS09340	COG2828	Protein conserved in bacteria
HU055_RS09390	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HU055_RS09395	COG0745	RESPONSE REGULATOR receiver
HU055_RS09400	COG3012	SEC-C Motif Domain Protein
HU055_RS09405	COG0788	formyltetrahydrofolate deformylase activity
HU055_RS09440	COG0708	Exodeoxyribonuclease III
HU055_RS09455	COG0778	Nitroreductase
HU055_RS09460	COG0616	signal peptide processing
HU055_RS09465	COG0252	asparaginase activity
HU055_RS09470	COG1335	isochorismatase
HU055_RS09475	COG3139	Protein of unknown function (DUF1315)
HU055_RS09480	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HU055_RS09495	COG0656	L-ascorbic acid biosynthetic process
HU055_RS09500	COG3713	MltA-interacting MipA family protein
HU055_RS09505	COG2766	serine protein kinase
HU055_RS09510	COG2718	Belongs to the UPF0229 family
HU055_RS09535	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HU055_RS09540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HU055_RS09545	COG2719	SpoVR family
HU055_RS09550	COG2186	Transcriptional regulator
HU055_RS09565	COG0179	Fumarylacetoacetate (FAA) hydrolase
HU055_RS09570	COG3100	YcgL domain-containing protein
HU055_RS09575	COG0850	regulation of cytokinetic process
HU055_RS09580	COG2894	cell division
HU055_RS09585	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
HU055_RS09595	COG0318	PFAM AMP-dependent synthetase and ligase
HU055_RS09600	COG3065	identical protein binding
HU055_RS09610	COG1199	ATP-dependent helicase activity
HU055_RS09615	COG0251	oxidation-reduction process
HU055_RS09620	COG3140	Belongs to the UPF0181 family
HU055_RS09635	COG1760	l-serine dehydratase
HU055_RS09640	COG1253	flavin adenine dinucleotide binding
HU055_RS09645	COG2226	methyltransferase
HU055_RS09675	COG0501	Belongs to the peptidase M48B family
HU055_RS09685	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
HU055_RS09690	COG1956	GAF domain-containing protein
HU055_RS09695	COG2995	paraquat-inducible protein a
HU055_RS09700	COG3008	intermembrane lipid transfer
HU055_RS09705	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
HU055_RS09705	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HU055_RS09720	COG0628	permease
HU055_RS09770	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HU055_RS09775	COG1770	oligopeptidase
HU055_RS09780	COG1082	Xylose isomerase domain protein TIM barrel
HU055_RS09785	COG3141	response to X-ray
HU055_RS09790	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HU055_RS09795	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HU055_RS09800	COG0469	pyruvate kinase activity
HU055_RS09810	COG1560	Kdo2-lipid A biosynthetic process
HU055_RS09815	COG0739	heme binding
HU055_RS09820	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HU055_RS09830	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HU055_RS09835	COG2255	four-way junction helicase activity
HU055_RS09840	COG0632	four-way junction helicase activity
HU055_RS09845	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HU055_RS09850	COG0217	transcriptional regulatory protein
HU055_RS09855	COG0494	nUDIX hydrolase
HU055_RS09860	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HU055_RS09865	COG1801	Protein of unknown function DUF72
HU055_RS09870	COG3788	relative of glutathione S-transferase, MAPEG superfamily
HU055_RS09875	COG2226	methyltransferase
HU055_RS09880	COG0500	methyltransferase
HU055_RS09890	COG3142	Participates in the control of copper homeostasis
HU055_RS09895	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HU055_RS09900	COG3102	Protein conserved in bacteria
HU055_RS09905	COG0018	arginyl-trna synthetase
HU055_RS09920	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HU055_RS09930	COG0745	RESPONSE REGULATOR receiver
HU055_RS09940	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HU055_RS09960	COG0835	chemotaxis
HU055_RS10015	COG0113	porphobilinogen synthase activity
HU055_RS10020	COG0431	NADPH-dependent FMN reductase
HU055_RS10030	COG2244	polysaccharide biosynthetic process
HU055_RS10035	COG1216	Glycosyl transferase, family 2
HU055_RS10040	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HU055_RS10045	COG1012	belongs to the aldehyde dehydrogenase family
HU055_RS10055	COG3381	protein complex oligomerization
HU055_RS10080	COG0778	Nitroreductase
HU055_RS10095	COG1702	phosphate starvation-inducible protein PhoH
HU055_RS10120	COG0506	proline dehydrogenase activity
HU055_RS10120	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HU055_RS10120	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HU055_RS10125	COG4763	Acyl-transferase
HU055_RS10150	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HU055_RS10150	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HU055_RS10155	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HU055_RS10160	COG1516	flagellar protein fliS
HU055_RS10170	COG0366	Alpha amylase catalytic
HU055_RS10185	COG5475	Uncharacterized small protein (DUF2158)
HU055_RS10190	COG2354	Protein conserved in bacteria
HU055_RS10200	COG3727	T/G mismatch-specific endonuclease activity
HU055_RS10210	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HU055_RS10215	COG1418	mRNA catabolic process
HU055_RS10225	COG3228	Belongs to the MtfA family
HU055_RS10235	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
HU055_RS10240	COG0803	Belongs to the bacterial solute-binding protein 9 family
HU055_RS10245	COG1121	(ABC) transporter
HU055_RS10250	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HU055_RS10255	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HU055_RS10285	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HU055_RS10295	COG4172	Belongs to the ABC transporter superfamily
HU055_RS10300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HU055_RS10305	COG0601	transmembrane transport
HU055_RS10310	COG0747	negative chemotaxis
HU055_RS10355	COG1280	lysine exporter protein (LysE YggA)
HU055_RS10360	COG0583	DNA-binding transcription factor activity
HU055_RS10400	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HU055_RS10405	COG1063	alcohol dehydrogenase
HU055_RS10410	COG3284	Transcriptional regulator
HU055_RS10420	COG1522	sequence-specific DNA binding
HU055_RS10440	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HU055_RS10445	COG0077	Prephenate dehydratase
HU055_RS10460	COG1280	lysine exporter protein (LysE YggA)
HU055_RS10465	COG0596	Alpha beta hydrolase
HU055_RS10475	COG0534	Mate efflux family protein
HU055_RS10480	COG2926	Belongs to the UPF0265 family
HU055_RS10485	COG1289	transmembrane transporter activity
HU055_RS10490	COG2925	Exonuclease
HU055_RS10495	COG0531	amino acid
HU055_RS10500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HU055_RS10510	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HU055_RS10520	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HU055_RS10525	COG0131	Imidazoleglycerol-phosphate dehydratase
HU055_RS10525	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HU055_RS10530	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HU055_RS10535	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HU055_RS10545	COG0140	phosphoribosyl-ATP diphosphatase activity
HU055_RS10545	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HU055_RS10550	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HU055_RS10580	COG1442	glycosyl transferase family 8
HU055_RS10615	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HU055_RS10680	COG1253	flavin adenine dinucleotide binding
HU055_RS10685	COG2982	Protein involved in outer membrane biogenesis
HU055_RS10690	COG0717	Belongs to the dCTP deaminase family
HU055_RS10695	COG0572	uridine kinase
HU055_RS10705	COG5002	protein histidine kinase activity
HU055_RS10705	COG3447	MASE1 domain protein
HU055_RS10705	COG5001	Diguanylate cyclase
HU055_RS10710	COG0443	Heat shock 70 kDa protein
HU055_RS10735	COG2205	protein histidine kinase activity
HU055_RS10740	COG0745	RESPONSE REGULATOR receiver
HU055_RS10760	COG1597	lipid kinase activity
HU055_RS10765	COG0351	phosphomethylpyrimidine kinase
HU055_RS10770	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HU055_RS10780	COG1605	Chorismate mutase
HU055_RS10795	COG0489	protein tyrosine kinase activity
HU055_RS10800	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HU055_RS10800	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HU055_RS10805	COG1380	Effector of murein hydrolase LrgA
HU055_RS10810	COG1346	cytolysis
HU055_RS10815	COG0295	cytidine deaminase activity
HU055_RS10820	COG0281	malic enzyme
HU055_RS10825	COG2949	membrane
HU055_RS10835	COG1129	ABC transporter
HU055_RS10845	COG1609	Transcriptional regulator
HU055_RS10850	COG2311	Membrane
HU055_RS10855	COG0302	gtp cyclohydrolase
HU055_RS10860	COG0583	DNA-binding transcription factor activity
HU055_RS10880	COG1120	ATPase activity
HU055_RS10885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HU055_RS10890	COG0833	amino acid
HU055_RS10895	COG0583	DNA-binding transcription factor activity
HU055_RS10900	COG2855	membrane
HU055_RS10905	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HU055_RS10910	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HU055_RS10910	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HU055_RS10910	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HU055_RS10915	COG1105	Belongs to the carbohydrate kinase PfkB family
HU055_RS10920	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HU055_RS10920	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HU055_RS10930	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HU055_RS10935	COG0671	phosphoesterase, PA-phosphatase related
HU055_RS10940	COG0791	NLP P60 protein
HU055_RS10945	COG2200	EAL domain
HU055_RS10950	COG4166	transmembrane transport
HU055_RS10955	COG4174	ABC transporter (Permease)
HU055_RS10960	COG4239	(ABC) transporter, permease
HU055_RS10965	COG4172	Belongs to the ABC transporter superfamily
HU055_RS10975	COG2814	Major facilitator Superfamily
HU055_RS10980	COG1187	pseudouridine synthase activity
HU055_RS10985	COG1061	Type III restriction enzyme res subunit
HU055_RS10990	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HU055_RS10995	COG3081	Nucleoid-associated protein
HU055_RS11000	COG3082	Protein of unknown function (DUF1414)
HU055_RS11005	COG3083	sulfuric ester hydrolase activity
HU055_RS11065	COG2977	Belongs to the P-Pant transferase superfamily
HU055_RS11075	COG3145	DNA-N1-methyladenine dioxygenase activity
HU055_RS11105	COG2197	response regulator
HU055_RS11110	COG2205	protein histidine kinase activity
HU055_RS11110	COG0784	Response regulator, receiver
HU055_RS11120	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HU055_RS11125	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HU055_RS11135	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HU055_RS11155	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
HU055_RS11170	COG4575	ribosome binding
HU055_RS11175	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
HU055_RS11180	COG2153	protein acetylation
HU055_RS11195	COG1007	ATP synthesis coupled electron transport
HU055_RS11200	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HU055_RS11205	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HU055_RS11210	COG0713	ATP synthesis coupled electron transport
HU055_RS11215	COG0839	Belongs to the complex I subunit 6 family
HU055_RS11220	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HU055_RS11225	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HU055_RS11235	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HU055_RS11245	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HU055_RS11245	COG0649	NAD binding
HU055_RS11250	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HU055_RS11255	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HU055_RS11260	COG0583	DNA-binding transcription factor activity
HU055_RS11265	COG0436	Aminotransferase
HU055_RS11270	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
HU055_RS11290	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HU055_RS11295	COG3092	negative regulation of chromosome organization
HU055_RS11300	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HU055_RS11305	COG0857	belongs to the CobB CobQ family
HU055_RS11305	COG0280	phosphate acetyltransferase
HU055_RS11310	COG3842	ATPase activity
HU055_RS11320	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HU055_RS11330	COG1176	ABC-type spermidine putrescine transport system, permease component I
HU055_RS11335	COG1177	transmembrane transport
HU055_RS11350	COG1090	epimerase
HU055_RS11355	COG4598	ABC transporter
HU055_RS11360	COG4160	amino acid transport
HU055_RS11375	COG0163	prenyltransferase activity
HU055_RS11380	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HU055_RS11385	COG1286	toxin biosynthetic process
HU055_RS11390	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
HU055_RS11395	COG0285	dihydrofolate synthase activity
HU055_RS11410	COG0586	Pfam SNARE associated Golgi protein
HU055_RS11420	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HU055_RS11430	COG2207	Transcriptional regulator
HU055_RS11475	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HU055_RS11490	COG3101	peptidyl-lysine hydroxylation
HU055_RS11495	COG0730	response to heat
HU055_RS11505	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HU055_RS11515	COG2840	Smr protein MutS2
HU055_RS11520	COG2062	phosphohistidine phosphatase, SixA
HU055_RS11525	COG1024	Enoyl-CoA hydratase
HU055_RS11525	COG1250	3-hydroxyacyl-CoA dehydrogenase
HU055_RS11530	COG0183	Belongs to the thiolase family
HU055_RS11545	COG2067	long-chain fatty acid transport protein
HU055_RS11555	COG4235	cytochrome complex assembly
HU055_RS11555	COG3088	subunit of a heme lyase
HU055_RS11560	COG3088	subunit of a heme lyase
HU055_RS11560	COG4235	cytochrome complex assembly
HU055_RS11570	COG1138	Cytochrome C-type biogenesis protein
HU055_RS11580	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HU055_RS11585	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HU055_RS11590	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HU055_RS11625	COG0668	transmembrane transport
HU055_RS11665	COG0436	Aminotransferase
HU055_RS11680	COG0837	glucose binding
HU055_RS11685	COG3961	Belongs to the TPP enzyme family
HU055_RS11690	COG0667	Aldo Keto reductase
HU055_RS11700	COG1914	H( )-stimulated, divalent metal cation uptake system
HU055_RS11705	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HU055_RS11720	COG2116	formate transmembrane transporter activity
HU055_RS11725	COG3415	Transposase
HU055_RS11730	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HU055_RS11775	COG0583	DNA-binding transcription factor activity
HU055_RS11780	COG0385	Bile acid
HU055_RS11785	COG3530	Putative quorum-sensing-regulated virulence factor
HU055_RS11790	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HU055_RS11795	COG3115	cell septum assembly
HU055_RS11800	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
HU055_RS11805	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HU055_RS11815	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HU055_RS11825	COG2205	protein histidine kinase activity
HU055_RS11830	COG0745	RESPONSE REGULATOR receiver
HU055_RS11840	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HU055_RS11845	COG4208	sulfate ABC transporter
HU055_RS11850	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HU055_RS11875	COG0860	N-Acetylmuramoyl-L-alanine amidase
HU055_RS11880	COG0408	coproporphyrinogen oxidase activity
HU055_RS11885	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HU055_RS11890	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HU055_RS11895	COG0494	nUDIX hydrolase
HU055_RS11910	COG3850	Histidine kinase
HU055_RS11915	COG2197	response regulator
HU055_RS11920	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HU055_RS11935	COG1393	Belongs to the ArsC family
HU055_RS11940	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HU055_RS11960	COG4104	PAAR repeat-containing protein
HU055_RS11960	COG3209	COG3209 Rhs family protein
HU055_RS11980	COG4104	PAAR repeat-containing protein
HU055_RS11980	COG3209	COG3209 Rhs family protein
HU055_RS11995	COG1444	tRNA N-acetyltransferase activity
HU055_RS12000	COG2321	neutral zinc metallopeptidase
HU055_RS12005	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HU055_RS12010	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HU055_RS12015	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HU055_RS12020	COG2716	regulation of RNA biosynthetic process
HU055_RS12025	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HU055_RS12030	COG3706	GGDEF domain
HU055_RS12040	COG1393	Belongs to the ArsC family
HU055_RS12045	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HU055_RS12050	COG2233	PERMEase
HU055_RS12060	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HU055_RS12065	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HU055_RS12070	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HU055_RS12075	COG0581	inorganic phosphate transmembrane transporter activity
HU055_RS12080	COG0573	inorganic phosphate transmembrane transporter activity
HU055_RS12085	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HU055_RS12095	COG0500	methyltransferase
HU055_RS12100	COG2200	EAL domain
HU055_RS12105	COG2239	Acts as a magnesium transporter
HU055_RS12110	COG2271	Major facilitator Superfamily
HU055_RS12115	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HU055_RS12130	COG3122	Protein conserved in bacteria
HU055_RS12165	COG0517	IMP dehydrogenase activity
HU055_RS12165	COG0516	GMP reductase activity
HU055_RS12170	COG1570	exodeoxyribonuclease VII activity
HU055_RS12185	COG4993	Dehydrogenase
HU055_RS12195	COG1160	GTP binding
HU055_RS12200	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HU055_RS12205	COG2976	Protein conserved in bacteria
HU055_RS12210	COG0124	histidyl-tRNA synthetase
HU055_RS12215	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HU055_RS12220	COG1426	Protein conserved in bacteria
HU055_RS12230	COG0820	rRNA (adenine-C2-)-methyltransferase activity
HU055_RS12235	COG0105	UTP biosynthetic process
HU055_RS12240	COG2897	thiosulfate sulfurtransferase activity
HU055_RS12250	COG1012	belongs to the aldehyde dehydrogenase family
HU055_RS12255	COG0446	pyridine nucleotide-disulphide oxidoreductase
HU055_RS12270	COG3938	Belongs to the proline racemase family
HU055_RS12280	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HU055_RS12285	COG0531	amino acid
HU055_RS12295	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HU055_RS12300	COG1104	cysteine desulfurase activity
HU055_RS12305	COG1959	2 iron, 2 sulfur cluster binding
HU055_RS12315	COG0483	inositol monophosphate 1-phosphatase activity
HU055_RS12320	COG3711	transcriptional antiterminator
HU055_RS12325	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HU055_RS12330	COG0347	Belongs to the P(II) protein family
HU055_RS12335	COG2204	response regulator
HU055_RS12340	COG3170	Tfp pilus assembly protein FimV
HU055_RS12345	COG2205	protein histidine kinase activity
HU055_RS12350	COG0047	phosphoribosylformylglycinamidine synthase activity
HU055_RS12350	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HU055_RS12355	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HU055_RS12365	COG0560	Phosphoserine phosphatase
HU055_RS12370	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HU055_RS12375	COG1737	Transcriptional regulator
HU055_RS12385	COG0736	holo-[acyl-carrier-protein] synthase activity
HU055_RS12390	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HU055_RS12395	COG1381	Involved in DNA repair and RecF pathway recombination
HU055_RS12405	COG0571	ribonuclease III activity
HU055_RS12415	COG0481	GTPase activity
HU055_RS12430	COG3086	response to oxidative stress
HU055_RS12435	COG3026	antisigma factor binding
HU055_RS12450	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HU055_RS12455	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HU055_RS12460	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
HU055_RS12465	COG0513	Belongs to the DEAD box helicase family
HU055_RS12470	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HU055_RS12475	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HU055_RS12480	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HU055_RS12485	COG0497	DNA recombination
HU055_RS12490	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HU055_RS12495	COG2914	Belongs to the UPF0125 (RnfH) family
HU055_RS12500	COG2867	negative regulation of translational initiation
HU055_RS12505	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HU055_RS12530	COG0835	chemotaxis
HU055_RS12565	COG0840	transmembrane signaling receptor activity
HU055_RS12570	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HU055_RS12580	COG1705	Flagellar rod assembly protein muramidase FlgJ
HU055_RS12580	COG3951	Flagellar rod assembly protein muramidase FlgJ
HU055_RS12590	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
HU055_RS12620	COG1815	bacterial-type flagellum-dependent cell motility
HU055_RS12635	COG3418	PFAM FlgN family protein
HU055_RS12680	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HU055_RS12680	COG4797	methyltransferase
HU055_RS12690	COG1987	bacterial-type flagellum assembly
HU055_RS12700	COG3190	flagellar
HU055_RS12705	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HU055_RS12715	COG1580	Controls the rotational direction of flagella during chemotaxis
HU055_RS12730	COG1157	protein secretion by the type III secretion system
HU055_RS12735	COG1317	bacterial-type flagellum organization
HU055_RS12750	COG1677	Flagellar hook-basal body complex protein FliE
HU055_RS12755	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HU055_RS12765	COG0745	RESPONSE REGULATOR receiver
HU055_RS12780	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HU055_RS12795	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HU055_RS12810	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HU055_RS12815	COG1780	Probably involved in ribonucleotide reductase function
HU055_RS12840	COG2113	Glycine betaine
HU055_RS12845	COG2814	Major facilitator Superfamily
HU055_RS12850	COG1846	Transcriptional regulator
HU055_RS12855	COG1566	PFAM secretion protein HlyD family protein
HU055_RS12860	COG2814	Major facilitator Superfamily
HU055_RS12865	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HU055_RS12870	COG3118	belongs to the thioredoxin family
HU055_RS12885	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HU055_RS12890	COG5544	Lipoprotein
HU055_RS12895	COG0477	Major facilitator Superfamily
HU055_RS12925	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HU055_RS12930	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HU055_RS12935	COG2011	ABC-type metal ion transport system permease component
HU055_RS12940	COG1464	Belongs to the NlpA lipoprotein family
HU055_RS12950	COG1720	tRNA m6t6A37 methyltransferase activity
HU055_RS12955	COG0442	prolyl-tRNA aminoacylation
HU055_RS12980	COG4568	rho-dependent transcription termination
HU055_RS12990	COG0037	tRNA processing
HU055_RS12995	COG0346	lactoylglutathione lyase activity
HU055_RS13005	COG0825	malonyl-CoA metabolic process
HU055_RS13015	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HU055_RS13020	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HU055_RS13025	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HU055_RS13030	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HU055_RS13035	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HU055_RS13040	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
HU055_RS13045	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HU055_RS13050	COG0750	zinc metalloprotease
HU055_RS13055	COG0575	Belongs to the CDS family
HU055_RS13060	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HU055_RS13065	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HU055_RS13070	COG0233	cytoplasmic translational termination
HU055_RS13075	COG0528	UMP kinase activity
HU055_RS13080	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HU055_RS13085	COG0052	Belongs to the universal ribosomal protein uS2 family
HU055_RS13095	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
HU055_RS13100	COG2171	N-acyltransferase activity
HU055_RS13110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HU055_RS13120	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HU055_RS13130	COG0316	Belongs to the HesB IscA family
HU055_RS13135	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HU055_RS13145	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HU055_RS13150	COG1120	ATPase activity
HU055_RS13165	COG2026	Addiction module toxin, RelE StbE family
HU055_RS13170	COG3077	Addiction module antitoxin, RelB DinJ family
HU055_RS13185	COG3209	COG3209 Rhs family protein
HU055_RS13185	COG4104	PAAR repeat-containing protein
HU055_RS13195	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HU055_RS13200	COG1643	Atp-dependent helicase
HU055_RS13205	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HU055_RS13210	COG1489	DNA binding
HU055_RS13230	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HU055_RS13235	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
HU055_RS13240	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HU055_RS13245	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HU055_RS13250	COG0842	Transport permease protein
HU055_RS13255	COG1131	(ABC) transporter
HU055_RS13260	COG0288	reversible hydration of carbon dioxide
HU055_RS13265	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
HU055_RS13290	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HU055_RS13295	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HU055_RS13300	COG3112	Uncharacterised protein family (UPF0231)
HU055_RS13320	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HU055_RS13325	COG1518	maintenance of DNA repeat elements
HU055_RS13340	COG1857	crispr-associated protein
HU055_RS13355	COG1203	CRISPR-associated helicase, Cas3
HU055_RS13360	COG2175	clavaminate synthase activity
HU055_RS13370	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
HU055_RS13375	COG1024	Enoyl-CoA hydratase
HU055_RS13380	COG0183	Belongs to the thiolase family
HU055_RS13385	COG0318	PFAM AMP-dependent synthetase and ligase
HU055_RS13400	COG1268	BioY protein
HU055_RS13405	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HU055_RS13410	COG1122	ATPase activity
HU055_RS13415	COG1028	Short-chain dehydrogenase reductase Sdr
HU055_RS13420	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HU055_RS13425	COG0508	dehydrogenase complex catalyzes the overall conversion of
HU055_RS13430	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HU055_RS13435	COG2186	Transcriptional regulator
HU055_RS13440	COG1113	amino acid transport
HU055_RS13445	COG2211	Major facilitator Superfamily
HU055_RS13450	COG3940	Belongs to the glycosyl hydrolase 43 family
HU055_RS13475	COG3725	Membrane protein required for beta-lactamase induction
HU055_RS13490	COG4969	Belongs to the N-Me-Phe pilin family
HU055_RS13495	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HU055_RS13500	COG1459	type II secretion system
HU055_RS13505	COG0516	GMP reductase activity
HU055_RS13515	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
HU055_RS13520	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
HU055_RS13525	COG0494	nUDIX hydrolase
HU055_RS13600	COG3397	chitin binding
HU055_RS13610	COG0653	protein targeting
HU055_RS13625	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
HU055_RS13630	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HU055_RS13635	COG0849	cell division
HU055_RS13645	COG1181	Belongs to the D-alanine--D-alanine ligase family
HU055_RS13655	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HU055_RS13660	COG0772	Belongs to the SEDS family
HU055_RS13675	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HU055_RS13680	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HU055_RS13685	COG0768	penicillin binding
HU055_RS13690	COG3116	cell division
HU055_RS13695	COG0275	rRNA processing
HU055_RS13700	COG2001	Belongs to the MraZ family
HU055_RS13715	COG0028	Belongs to the TPP enzyme family
HU055_RS13725	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HU055_RS13730	COG0473	3-isopropylmalate dehydrogenase activity
HU055_RS13740	COG0066	3-isopropylmalate dehydratase activity
HU055_RS13745	COG2814	Major facilitator Superfamily
HU055_RS13750	COG4533	DNA binding
HU055_RS13755	COG4143	(ABC) transporter
HU055_RS13760	COG1178	ABC-type Fe3 transport system permease component
HU055_RS13765	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
HU055_RS13770	COG0586	Pfam SNARE associated Golgi protein
HU055_RS13775	COG0417	DNA replication proofreading
HU055_RS13780	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HU055_RS13785	COG0564	pseudouridine synthase activity
HU055_RS13790	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HU055_RS13805	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HU055_RS13810	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HU055_RS13815	COG2967	ApaG domain
HU055_RS13820	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HU055_RS13825	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HU055_RS13830	COG1280	lysine exporter protein (LysE YggA)
HU055_RS13840	COG0505	Belongs to the CarA family
HU055_RS13845	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HU055_RS13850	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HU055_RS13855	COG1047	Peptidyl-prolyl cis-trans
HU055_RS13860	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HU055_RS13865	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HU055_RS13870	COG0196	riboflavin kinase activity
HU055_RS13875	COG0268	Binds directly to 16S ribosomal RNA
HU055_RS13880	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HU055_RS13885	COG0484	heat shock protein binding
HU055_RS13890	COG0443	Heat shock 70 kDa protein
HU055_RS13900	COG0521	Mo-molybdopterin cofactor biosynthetic process
HU055_RS13910	COG3022	response to hydroperoxide
HU055_RS13920	COG0083	homoserine kinase activity
HU055_RS13935	COG0745	RESPONSE REGULATOR receiver
HU055_RS13940	COG3045	CreA protein
HU055_RS13945	COG2207	Transcriptional regulator
HU055_RS13945	COG3708	Transcriptional regulator
HU055_RS13955	COG0406	alpha-ribazole phosphatase activity
HU055_RS13960	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
HU055_RS13965	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
HU055_RS13970	COG0741	lytic transglycosylase activity
HU055_RS13980	COG1349	DNA-binding transcription factor activity
HU055_RS13990	COG0488	(ABC) transporter
HU055_RS13995	COG0583	DNA-binding transcription factor activity
HU055_RS14000	COG0604	alcohol dehydrogenase
HU055_RS14025	COG0560	Phosphoserine phosphatase
HU055_RS14030	COG3726	membrane protein affecting hemolysin expression
HU055_RS14035	COG3550	peptidyl-serine autophosphorylation
HU055_RS14040	COG0813	purine-nucleoside phosphorylase activity
HU055_RS14045	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HU055_RS14050	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
HU055_RS14055	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HU055_RS14060	COG0084	hydrolase, TatD family'
HU055_RS14065	COG4667	esterase of the alpha-beta hydrolase superfamily
HU055_RS14070	COG5487	UPF0391 membrane protein
HU055_RS14075	COG2823	Periplasmic or secreted lipoprotein
HU055_RS14080	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HU055_RS14085	COG2755	lipolytic protein G-D-S-L family
HU055_RS14085	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HU055_RS14090	COG2818	Glycosylase
HU055_RS14095	COG1397	ADP-ribosylglycohydrolase
HU055_RS14130	COG3209	COG3209 Rhs family protein
HU055_RS14140	COG3501	Rhs element vgr protein
HU055_RS14160	COG3501	Rhs element vgr protein
HU055_RS14280	COG1011	Hydrolase
HU055_RS14285	COG0456	acetyltransferase
HU055_RS14290	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
HU055_RS14295	COG2813	Specifically methylates the guanine in position
HU055_RS14320	COG3706	GGDEF domain
HU055_RS14345	COG1609	Transcriptional regulator
HU055_RS14350	COG0477	Major facilitator Superfamily
HU055_RS14440	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HU055_RS14440	COG0517	IMP dehydrogenase activity
HU055_RS14445	COG1349	DNA-binding transcription factor activity
HU055_RS14450	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
HU055_RS14455	COG1028	Short-chain dehydrogenase reductase Sdr
HU055_RS14460	COG3731	PTS system glucitol sorbitol-specific IIA component
HU055_RS14485	COG0535	radical SAM domain protein
HU055_RS14495	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
HU055_RS14500	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HU055_RS14515	COG0659	secondary active sulfate transmembrane transporter activity
HU055_RS14520	COG0288	reversible hydration of carbon dioxide
HU055_RS14530	COG0446	pyridine nucleotide-disulphide oxidoreductase
HU055_RS14530	COG1902	pentaerythritol trinitrate reductase activity
HU055_RS14535	COG2813	Specifically methylates the guanine in position
HU055_RS14540	COG1451	nucleotide metabolic process
HU055_RS14550	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HU055_RS14555	COG1063	alcohol dehydrogenase
HU055_RS14560	COG0038	chloride channel
HU055_RS14565	COG0861	Integral membrane protein TerC family
HU055_RS14570	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HU055_RS14580	COG0586	Pfam SNARE associated Golgi protein
HU055_RS14590	COG1422	Protein of unknown function (DUF1090)
HU055_RS14595	COG4575	ribosome binding
HU055_RS14600	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
HU055_RS14610	COG2259	Doxx family
HU055_RS14620	COG0583	DNA-binding transcription factor activity
HU055_RS14625	COG1741	Belongs to the pirin family
HU055_RS14650	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HU055_RS14655	COG3107	peptidoglycan biosynthetic process
HU055_RS14660	COG0792	nuclease activity
HU055_RS14665	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
HU055_RS14670	COG2823	Periplasmic or secreted lipoprotein
HU055_RS14675	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HU055_RS14675	COG3711	transcriptional antiterminator
HU055_RS14690	COG3964	amidohydrolase
HU055_RS14725	COG0312	modulator of DNA gyrase
HU055_RS14730	COG3028	Belongs to the UPF0307 family
HU055_RS14735	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HU055_RS14740	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
HU055_RS14745	COG0840	transmembrane signaling receptor activity
HU055_RS14755	COG2105	PFAM AIG2 family protein
HU055_RS14765	COG0729	surface antigen
HU055_RS14770	COG1253	flavin adenine dinucleotide binding
HU055_RS14780	COG1218	3'(2'),5'-bisphosphate nucleotidase
HU055_RS14790	COG0545	Peptidyl-prolyl cis-trans isomerase
HU055_RS14795	COG3061	Opacity-associated protein A
HU055_RS14800	COG0359	binds to the 23S rRNA
HU055_RS14805	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HU055_RS14810	COG2965	DNA replication, synthesis of RNA primer
HU055_RS14815	COG0360	Binds together with S18 to 16S ribosomal RNA
HU055_RS14820	COG1073	alpha beta
HU055_RS14825	COG0840	transmembrane signaling receptor activity
HU055_RS14835	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HU055_RS14840	COG0557	exoribonuclease II activity
HU055_RS14845	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HU055_RS14850	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
HU055_RS14855	COG0330	HflC and HflK could
HU055_RS14860	COG0330	HflC and HflK could
HU055_RS14865	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HU055_RS14875	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HU055_RS14880	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HU055_RS14885	COG0860	N-Acetylmuramoyl-L-alanine amidase
HU055_RS14890	COG0802	atpase or kinase
HU055_RS14895	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HU055_RS14895	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HU055_RS14920	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HU055_RS14925	COG1162	GTPase activity
HU055_RS14930	COG0688	phosphatidylethanolamine metabolic process
HU055_RS14935	COG3264	Mechanosensitive ion channel
HU055_RS14935	COG1511	domain protein
HU055_RS14940	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
HU055_RS14945	COG3040	lipid binding
HU055_RS14960	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HU055_RS14965	COG1509	lysine 2,3-aminomutase activity
HU055_RS14975	COG0459	protein refolding
HU055_RS14980	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HU055_RS14985	COG3030	protein affecting phage T7 exclusion by the F plasmid
HU055_RS14990	COG1027	Aspartate ammonia-lyase
HU055_RS14995	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HU055_RS15005	COG1309	transcriptional regulator
HU055_RS15020	COG2211	Major facilitator Superfamily
HU055_RS15030	COG0367	asparagine synthase
HU055_RS15045	COG0124	histidyl-tRNA synthetase
HU055_RS15060	COG2890	protein-(glutamine-N5) methyltransferase activity
HU055_RS15070	COG1181	Belongs to the D-alanine--D-alanine ligase family
HU055_RS15245	COG0076	glutamate decarboxylase activity
HU055_RS15250	COG3486	L-lysine 6-monooxygenase (NADPH) activity
HU055_RS15260	COG4774	siderophore transport
HU055_RS15270	COG1028	Short-chain dehydrogenase reductase Sdr
HU055_RS15280	COG1902	pentaerythritol trinitrate reductase activity
HU055_RS15290	COG0561	phosphatase activity
HU055_RS15300	COG2382	esterase
HU055_RS15310	COG1280	lysine exporter protein (LysE YggA)
HU055_RS15315	COG0583	DNA-binding transcription factor activity
HU055_RS15330	COG0583	DNA-binding transcription factor activity
HU055_RS15365	COG3300	MHYT domain
HU055_RS15365	COG5001	Diguanylate cyclase
HU055_RS15370	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HU055_RS15390	COG0840	transmembrane signaling receptor activity
HU055_RS15395	COG1301	dicarboxylic acid transport
HU055_RS15405	COG3162	membrane
HU055_RS15410	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HU055_RS15420	COG1346	cytolysis
HU055_RS15425	COG1380	Effector of murein hydrolase LrgA
HU055_RS15430	COG0583	DNA-binding transcription factor activity
HU055_RS15435	COG0025	NhaP-type Na H and K H
HU055_RS15440	COG2252	PERMEase
HU055_RS15445	COG0625	glutathione transferase activity
HU055_RS15475	COG2831	hemolysin activation secretion protein
HU055_RS15480	COG0629	single-stranded DNA binding
HU055_RS15485	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HU055_RS15490	COG1064	alcohol dehydrogenase
HU055_RS15495	COG1388	LysM domain
HU055_RS15495	COG1470	cell adhesion involved in biofilm formation
HU055_RS15500	COG2315	Protein conserved in bacteria
HU055_RS15510	COG1448	Aminotransferase
HU055_RS15535	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HU055_RS15550	COG2246	polysaccharide biosynthetic process
HU055_RS15615	COG1403	HNH endonuclease
HU055_RS15635	COG0735	belongs to the Fur family
HU055_RS15640	COG3237	CsbD-like
HU055_RS15645	COG0534	Mate efflux family protein
HU055_RS15650	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HU055_RS15655	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HU055_RS15670	COG3161	chorismate lyase activity
HU055_RS15675	COG3223	Belongs to the PsiE family
HU055_RS15680	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HU055_RS15700	COG0166	Belongs to the GPI family
HU055_RS15705	COG0527	aspartate kinase activity
HU055_RS15710	COG1283	sodium-dependent phosphate transmembrane transporter activity
HU055_RS15715	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
HU055_RS15740	COG0138	bifunctional purine biosynthesis protein purh
HU055_RS15745	COG0151	Belongs to the GarS family
HU055_RS15765	COG1515	deoxyribonuclease V activity
HU055_RS15770	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HU055_RS15775	COG2816	NAD+ diphosphatase activity
HU055_RS15780	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
HU055_RS15785	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HU055_RS15795	COG4571	Outer membrane protease
HU055_RS15840	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HU055_RS15845	COG0085	RNA polymerase activity
HU055_RS15850	COG0222	ribosome binding
HU055_RS15855	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HU055_RS15860	COG0081	regulation of translation
HU055_RS15865	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HU055_RS15870	COG0250	Participates in transcription elongation, termination and antitermination
HU055_RS15905	COG1072	(Pantothenic acid kinase))
HU055_RS15910	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
HU055_RS15910	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
HU055_RS15940	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
HU055_RS15945	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HU055_RS15950	COG1739	Uncharacterized protein family UPF0029
HU055_RS15955	COG0006	proline dipeptidase activity
HU055_RS15965	COG0183	Belongs to the thiolase family
HU055_RS15975	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HU055_RS15990	COG0805	protein transport
HU055_RS15995	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HU055_RS16005	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HU055_RS16015	COG2226	methyltransferase
HU055_RS16020	COG1322	Protein conserved in bacteria
HU055_RS16030	COG0412	Dienelactone hydrolase
HU055_RS16035	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HU055_RS16040	COG0583	DNA-binding transcription factor activity
HU055_RS16045	COG4807	Protein conserved in bacteria
HU055_RS16050	COG2271	Major facilitator Superfamily
HU055_RS16055	COG0561	phosphatase activity
HU055_RS16060	COG2267	carboxylic ester hydrolase activity
HU055_RS16065	COG1280	lysine exporter protein (LysE YggA)
HU055_RS16070	COG0514	ATP-dependent DNA helicase (RecQ)
HU055_RS16075	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
HU055_RS16080	COG2050	protein possibly involved in aromatic compounds catabolism
HU055_RS16085	COG0598	Magnesium transport protein CorA
HU055_RS16090	COG0210	DNA helicase
HU055_RS16095	COG1011	Hydrolase
HU055_RS16105	COG3159	Protein conserved in bacteria
HU055_RS16110	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HU055_RS16120	COG3072	Adenylate cyclase
HU055_RS16125	COG0181	hydroxymethylbilane synthase activity
HU055_RS16130	COG1587	Uroporphyrinogen-III synthase
HU055_RS16135	COG2959	enzyme of heme biosynthesis
HU055_RS16140	COG3071	HemY protein
HU055_RS16180	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
HU055_RS16190	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HU055_RS16195	COG2244	polysaccharide biosynthetic process
HU055_RS16200	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HU055_RS16205	COG0456	acetyltransferase
HU055_RS16210	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HU055_RS16215	COG1088	dTDP-glucose 4,6-dehydratase activity
HU055_RS16220	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HU055_RS16225	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HU055_RS16235	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HU055_RS16240	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HU055_RS16245	COG3118	belongs to the thioredoxin family
HU055_RS16250	COG0513	Belongs to the DEAD box helicase family
HU055_RS16255	COG0248	Ppx GppA phosphatase
HU055_RS16270	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HU055_RS16280	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HU055_RS16285	COG0129	dihydroxy-acid dehydratase activity
HU055_RS16295	COG3978	acetolactate synthase activity
HU055_RS16310	COG0606	chelatase, subunit chli
HU055_RS16315	COG3085	chromosome segregation
HU055_RS16320	COG0583	DNA-binding transcription factor activity
HU055_RS16355	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HU055_RS16360	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HU055_RS16370	COG1309	transcriptional regulator
HU055_RS16375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HU055_RS16385	COG0678	peroxiredoxin activity
HU055_RS16385	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HU055_RS16390	COG0165	Argininosuccinate lyase
HU055_RS16395	COG0137	argininosuccinate synthase activity
HU055_RS16405	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HU055_RS16410	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HU055_RS16420	COG0527	aspartate kinase activity
HU055_RS16420	COG0460	homoserine dehydrogenase
HU055_RS16425	COG0626	cystathionine gamma-synthase activity
HU055_RS16430	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
HU055_RS16435	COG0254	rRNA binding
HU055_RS16440	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HU055_RS16445	COG1609	Transcriptional regulator
HU055_RS16450	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HU055_RS16455	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HU055_RS16460	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HU055_RS16465	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HU055_RS16470	COG3074	FtsZ-dependent cytokinesis
HU055_RS16475	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HU055_RS16490	COG1494	fructose-1,6-bisphosphatase
HU055_RS16495	COG2814	Major facilitator Superfamily
HU055_RS16520	COG0149	triose-phosphate isomerase activity
HU055_RS16545	COG1295	ribonuclease BN
HU055_RS16555	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HU055_RS16560	COG0205	6-phosphofructokinase activity
HU055_RS16570	COG3678	ATP-independent chaperone mediated protein folding
HU055_RS16575	COG0745	RESPONSE REGULATOR receiver
HU055_RS16585	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HU055_RS16595	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HU055_RS16600	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
HU055_RS16605	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HU055_RS16610	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HU055_RS16615	COG4942	peptidase
HU055_RS16620	COG2861	carbohydrate metabolic process
HU055_RS16625	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HU055_RS16630	COG0859	PFAM glycosyl transferase family 9
HU055_RS16635	COG0859	PFAM glycosyl transferase family 9
HU055_RS16640	COG0438	transferase activity, transferring glycosyl groups
HU055_RS16645	COG3307	-O-antigen
HU055_RS16650	COG1215	transferase activity, transferring glycosyl groups
HU055_RS16665	COG0859	PFAM glycosyl transferase family 9
HU055_RS16675	COG0438	transferase activity, transferring glycosyl groups
HU055_RS16680	COG0859	PFAM glycosyl transferase family 9
HU055_RS16685	COG1519	Transferase
HU055_RS16695	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HU055_RS16700	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HU055_RS16710	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HU055_RS16715	COG2003	Belongs to the UPF0758 family
HU055_RS16720	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HU055_RS16725	COG0756	dUTP diphosphatase activity
HU055_RS16730	COG1309	transcriptional regulator
HU055_RS16735	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HU055_RS16740	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HU055_RS16745	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HU055_RS16755	COG1561	YicC-like family, N-terminal region
HU055_RS16770	COG1401	restriction endodeoxyribonuclease activity
HU055_RS16825	COG2824	Alkylphosphonate utilization operon protein PhnA
HU055_RS16835	COG2197	response regulator
HU055_RS16840	COG2860	membrane
HU055_RS16850	COG0194	GDP metabolic process
HU055_RS16855	COG1758	RNA polymerase activity
HU055_RS16860	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HU055_RS16865	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HU055_RS16870	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HU055_RS16875	COG2233	PERMEase
HU055_RS16880	COG2982	Protein involved in outer membrane biogenesis
HU055_RS16885	COG1187	pseudouridine synthase activity
HU055_RS16890	COG0456	acetyltransferase
HU055_RS16895	COG1490	D-aminoacyl-tRNA deacylase activity
HU055_RS16905	COG1011	Hydrolase
HU055_RS16920	COG3852	Histidine kinase
HU055_RS16935	COG3078	GTPase activator activity
HU055_RS16945	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HU055_RS16945	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HU055_RS16960	COG3084	Protein conserved in bacteria
HU055_RS16995	COG0477	Major facilitator Superfamily
HU055_RS17000	COG1609	Transcriptional regulator
HU055_RS17005	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HU055_RS17010	COG1879	ABC-type sugar transport system periplasmic component
HU055_RS17015	COG1172	Belongs to the binding-protein-dependent transport system permease family
HU055_RS17020	COG1129	ABC transporter
HU055_RS17045	COG3111	PFAM Bacterial OB fold (BOF) protein
HU055_RS17065	COG3158	transport of potassium into the cell
HU055_RS17075	COG2425	protein containing a von Willebrand factor type A (vWA) domain
HU055_RS17085	COG1522	sequence-specific DNA binding
HU055_RS17090	COG0716	FMN binding
HU055_RS17100	COG0357	Ribosomal RNA small subunit methyltransferase G
HU055_RS17105	COG3312	ion transport
HU055_RS17110	COG0356	it plays a direct role in the translocation of protons across the membrane
HU055_RS17120	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HU055_RS17125	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HU055_RS17130	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HU055_RS17135	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HU055_RS17140	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HU055_RS17145	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HU055_RS17155	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HU055_RS17175	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HU055_RS17180	COG0573	inorganic phosphate transmembrane transporter activity
HU055_RS17185	COG0581	inorganic phosphate transmembrane transporter activity
HU055_RS17190	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HU055_RS17195	COG0704	Plays a role in the regulation of phosphate uptake
HU055_RS17200	COG2814	Major facilitator Superfamily
HU055_RS17210	COG2252	PERMEase
HU055_RS17215	COG2091	lysine biosynthetic process via aminoadipic acid
HU055_RS17220	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HU055_RS17225	COG0706	membrane insertase activity
HU055_RS17235	COG0594	ribonuclease P activity
HU055_RS17240	COG0230	Belongs to the bacterial ribosomal protein bL34 family
HU055_RS17290	COG1192	Involved in chromosome partitioning
HU055_RS17355	COG4628	conserved protein (DUF2132)