locus-tag	class	description
EYR00_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EYR00_RS00010	COG0592	DNA-directed DNA polymerase activity
EYR00_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EYR00_RS00025	COG0187	DNA topoisomerase II activity
EYR00_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EYR00_RS00060	COG1757	Na H antiporter
EYR00_RS00065	COG5001	Diguanylate cyclase
EYR00_RS00065	COG3300	MHYT domain
EYR00_RS00085	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EYR00_RS00090	COG0561	phosphatase activity
EYR00_RS00120	COG1131	(ABC) transporter
EYR00_RS00155	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EYR00_RS00160	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EYR00_RS00175	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EYR00_RS00180	COG0470	DNA polymerase III
EYR00_RS00185	COG1774	PSP1 C-terminal conserved region
EYR00_RS00190	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EYR00_RS00195	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EYR00_RS00200	COG0726	polysaccharide deacetylase
EYR00_RS00205	COG2357	RelA SpoT domain protein
EYR00_RS00215	COG2188	Transcriptional regulator
EYR00_RS00245	COG5012	cobalamin binding
EYR00_RS00255	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EYR00_RS00265	COG5001	Diguanylate cyclase
EYR00_RS00270	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EYR00_RS00275	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EYR00_RS00280	COG4821	SIS domain
EYR00_RS00285	COG4821	SIS domain
EYR00_RS00290	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYR00_RS00290	COG3711	transcriptional antiterminator
EYR00_RS00330	COG1316	TRANSCRIPTIONal
EYR00_RS00365	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EYR00_RS00370	COG0363	glucosamine-6-phosphate deaminase activity
EYR00_RS00375	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYR00_RS00385	COG1737	Transcriptional regulator
EYR00_RS00390	COG4978	Transcriptional regulator
EYR00_RS00390	COG0789	Transcriptional regulator
EYR00_RS00415	COG5263	repeat protein
EYR00_RS00415	COG4193	domain, Protein
EYR00_RS00435	COG0438	transferase activity, transferring glycosyl groups
EYR00_RS00435	COG1216	Glycosyl transferase, family 2
EYR00_RS00440	COG0438	transferase activity, transferring glycosyl groups
EYR00_RS00440	COG1216	Glycosyl transferase, family 2
EYR00_RS00460	COG1216	Glycosyl transferase, family 2
EYR00_RS00470	COG0438	transferase activity, transferring glycosyl groups
EYR00_RS00475	COG0562	UDP-galactopyranose mutase
EYR00_RS00495	COG1368	sulfuric ester hydrolase activity
EYR00_RS00540	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYR00_RS00550	COG2723	6-phospho-beta-galactosidase activity
EYR00_RS00570	COG0009	L-threonylcarbamoyladenylate synthase
EYR00_RS00575	COG0698	ribose 5-phosphate isomerase
EYR00_RS00580	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EYR00_RS00585	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EYR00_RS00605	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EYR00_RS00615	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EYR00_RS00620	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EYR00_RS00625	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EYR00_RS00630	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EYR00_RS00635	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EYR00_RS00645	COG1982	Orn Lys Arg decarboxylase major
EYR00_RS00650	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EYR00_RS00655	COG0010	Belongs to the arginase family
EYR00_RS00670	COG0561	phosphatase activity
EYR00_RS00685	COG0860	N-Acetylmuramoyl-L-alanine amidase
EYR00_RS00690	COG3409	Peptidoglycan-binding domain 1 protein
EYR00_RS00690	COG0793	Belongs to the peptidase S41A family
EYR00_RS00695	COG0556	nucleotide-excision repair
EYR00_RS00700	COG0617	tRNA 3'-terminal CCA addition
EYR00_RS00705	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EYR00_RS00710	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EYR00_RS00715	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EYR00_RS00720	COG2188	Transcriptional regulator
EYR00_RS00725	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYR00_RS00730	COG2723	6-phospho-beta-galactosidase activity
EYR00_RS00740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYR00_RS00740	COG2190	(PTS) system
EYR00_RS00740	COG1263	PTS System
EYR00_RS00745	COG3711	transcriptional antiterminator
EYR00_RS00755	COG3715	PTS system
EYR00_RS00760	COG3716	PTS system mannose fructose sorbose family IID component
EYR00_RS00775	COG2205	protein histidine kinase activity
EYR00_RS00785	COG1132	(ABC) transporter
EYR00_RS00790	COG0561	phosphatase activity
EYR00_RS00800	COG3191	aminopeptidase activity
EYR00_RS00815	COG2169	Transcriptional regulator
EYR00_RS00820	COG0655	NAD(P)H dehydrogenase (quinone) activity
EYR00_RS00830	COG0492	ferredoxin-NADP+ reductase activity
EYR00_RS00835	COG0583	DNA-binding transcription factor activity
EYR00_RS00855	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EYR00_RS00860	COG0181	hydroxymethylbilane synthase activity
EYR00_RS00870	COG0113	porphobilinogen synthase activity
EYR00_RS00875	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EYR00_RS00880	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EYR00_RS00880	COG1648	precorrin-2 dehydrogenase activity
EYR00_RS00895	COG2268	Band 7 protein
EYR00_RS00905	COG1660	Displays ATPase and GTPase activities
EYR00_RS00930	COG0534	Mate efflux family protein
EYR00_RS00945	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EYR00_RS00960	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EYR00_RS00965	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EYR00_RS00985	COG0583	DNA-binding transcription factor activity
EYR00_RS01000	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EYR00_RS01005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EYR00_RS01010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EYR00_RS01015	COG1120	ATPase activity
EYR00_RS01055	COG0569	domain protein
EYR00_RS01060	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EYR00_RS01065	COG0084	hydrolase, TatD family'
EYR00_RS01105	COG0357	Ribosomal RNA small subunit methyltransferase G
EYR00_RS01120	COG1393	Belongs to the ArsC family
EYR00_RS01140	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EYR00_RS01150	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYR00_RS01155	COG3711	transcriptional antiterminator
EYR00_RS01155	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYR00_RS01160	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYR00_RS01165	COG3394	polysaccharide catabolic process
EYR00_RS01175	COG1132	(ABC) transporter
EYR00_RS01180	COG1132	(ABC) transporter
EYR00_RS01185	COG0745	RESPONSE REGULATOR receiver
EYR00_RS01190	COG1131	(ABC) transporter
EYR00_RS01220	COG0756	dUTP diphosphatase activity
EYR00_RS01225	COG0642	Histidine kinase
EYR00_RS01225	COG5002	protein histidine kinase activity
EYR00_RS01230	COG0745	RESPONSE REGULATOR receiver
EYR00_RS01245	COG0463	Glycosyl transferase, family 2
EYR00_RS01255	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYR00_RS01265	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYR00_RS01285	COG0534	Mate efflux family protein
EYR00_RS01315	COG1328	CTP reductase activity
EYR00_RS01320	COG0602	queuosine metabolic process
EYR00_RS01330	COG2723	6-phospho-beta-galactosidase activity
EYR00_RS01340	COG1183	phosphatidylcholine synthase activity
EYR00_RS01345	COG0688	phosphatidylethanolamine metabolic process
EYR00_RS01350	COG1192	Involved in chromosome partitioning
EYR00_RS01355	COG1475	DNA binding
EYR00_RS01375	COG0534	Mate efflux family protein
EYR00_RS01385	COG0673	inositol 2-dehydrogenase activity
EYR00_RS01390	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYR00_RS01405	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYR00_RS01420	COG2723	6-phospho-beta-galactosidase activity
EYR00_RS01425	COG4978	Transcriptional regulator
EYR00_RS01425	COG0789	Transcriptional regulator
EYR00_RS01435	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EYR00_RS01445	COG2203	Gaf domain
EYR00_RS01445	COG2199	diguanylate cyclase activity
EYR00_RS01455	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EYR00_RS01460	COG0359	binds to the 23S rRNA
EYR00_RS01465	COG0305	Participates in initiation and elongation during chromosome replication
EYR00_RS01470	COG1435	thymidine kinase activity
EYR00_RS01475	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EYR00_RS01480	COG2890	protein-(glutamine-N5) methyltransferase activity
EYR00_RS01490	COG2723	6-phospho-beta-galactosidase activity
EYR00_RS01510	COG2832	Protein of unknown function (DUF454)
EYR00_RS01515	COG4988	ABC transporter
EYR00_RS01520	COG1132	(ABC) transporter
EYR00_RS01530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EYR00_RS01550	COG0513	Belongs to the DEAD box helicase family
EYR00_RS01555	COG0037	tRNA processing
EYR00_RS01555	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EYR00_RS01560	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EYR00_RS01565	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EYR00_RS01575	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EYR00_RS01585	COG4481	Protein conserved in bacteria
EYR00_RS01595	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYR00_RS01600	COG0383	alpha-mannosidase activity
EYR00_RS01625	COG1136	(ABC) transporter
EYR00_RS01635	COG1876	peptidase activity
EYR00_RS01640	COG2843	Capsule synthesis protein
EYR00_RS01655	COG3326	Membrane
EYR00_RS01660	COG2226	methyltransferase
EYR00_RS01665	COG1408	metallophosphoesterase
EYR00_RS01670	COG1408	metallophosphoesterase
EYR00_RS01680	COG1247	-acetyltransferase
EYR00_RS01690	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EYR00_RS01695	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EYR00_RS01710	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EYR00_RS01715	COG0254	rRNA binding
EYR00_RS01720	COG0534	Mate efflux family protein
EYR00_RS01735	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EYR00_RS01750	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
EYR00_RS01760	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EYR00_RS01770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EYR00_RS01785	COG0622	Phosphoesterase
EYR00_RS01795	COG2188	Transcriptional regulator
EYR00_RS01800	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYR00_RS01825	COG1737	Transcriptional regulator
EYR00_RS01875	COG1115	amino acid carrier protein
EYR00_RS01890	COG0004	ammonium transporteR
EYR00_RS01900	COG1283	sodium-dependent phosphate transmembrane transporter activity
EYR00_RS01915	COG0745	RESPONSE REGULATOR receiver
EYR00_RS01920	COG5002	protein histidine kinase activity
EYR00_RS01930	COG2723	6-phospho-beta-galactosidase activity
EYR00_RS01950	COG0488	(ABC) transporter
EYR00_RS01960	COG0473	3-isopropylmalate dehydrogenase activity
EYR00_RS01965	COG1802	Transcriptional regulator
EYR00_RS01970	COG3279	Response regulator of the LytR AlgR family
EYR00_RS01995	COG1486	melibiose metabolic process
EYR00_RS02075	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EYR00_RS02115	COG0629	single-stranded DNA binding
EYR00_RS02165	COG3728	DNA packaging
EYR00_RS02170	COG1783	phage Terminase large subunit
EYR00_RS02310	COG1078	dGTPase activity
EYR00_RS02315	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EYR00_RS02325	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EYR00_RS02330	COG0018	arginyl-trna synthetase
EYR00_RS02335	COG3343	RNA polymerase activity
EYR00_RS02340	COG0398	Pfam SNARE associated Golgi protein
EYR00_RS02350	COG2205	protein histidine kinase activity
EYR00_RS02375	COG2801	Transposase and inactivated derivatives
EYR00_RS02400	COG1346	cytolysis
EYR00_RS02410	COG3300	MHYT domain
EYR00_RS02410	COG5001	Diguanylate cyclase
EYR00_RS02425	COG0791	NLP P60 protein
EYR00_RS02440	COG2267	carboxylic ester hydrolase activity
EYR00_RS02460	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EYR00_RS02470	COG0439	Biotin carboxylase
EYR00_RS02475	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EYR00_RS02480	COG0825	malonyl-CoA metabolic process
EYR00_RS02490	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EYR00_RS02505	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EYR00_RS02515	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EYR00_RS02520	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EYR00_RS02530	COG1473	amidohydrolase
EYR00_RS02535	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EYR00_RS02540	COG2011	ABC-type metal ion transport system permease component
EYR00_RS02555	COG0626	cystathionine gamma-synthase activity
EYR00_RS02560	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EYR00_RS02565	COG0789	Transcriptional regulator
EYR00_RS02570	COG0446	pyridine nucleotide-disulphide oxidoreductase
EYR00_RS02570	COG1902	pentaerythritol trinitrate reductase activity
EYR00_RS02575	COG2508	Transcriptional regulator
EYR00_RS02580	COG1940	carbohydrate kinase activity
EYR00_RS02595	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYR00_RS02625	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EYR00_RS02625	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EYR00_RS02630	COG2213	PTS system mannitol-specific
EYR00_RS02630	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYR00_RS02640	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYR00_RS02640	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYR00_RS02655	COG0523	cobalamin synthesis protein
EYR00_RS02660	COG1811	Na channel or pump
EYR00_RS02665	COG0673	inositol 2-dehydrogenase activity
EYR00_RS02670	COG0673	inositol 2-dehydrogenase activity
EYR00_RS02700	COG1263	PTS System
EYR00_RS02700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYR00_RS02705	COG2190	(PTS) system
EYR00_RS02705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYR00_RS02705	COG1263	PTS System
EYR00_RS02720	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYR00_RS02720	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EYR00_RS02720	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EYR00_RS02725	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EYR00_RS02730	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EYR00_RS02740	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EYR00_RS02745	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EYR00_RS02770	COG1846	Transcriptional regulator
EYR00_RS02775	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EYR00_RS02805	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYR00_RS02815	COG0300	oxidoreductase activity
EYR00_RS02825	COG1869	D-ribose catabolic process
EYR00_RS02845	COG1187	pseudouridine synthase activity
EYR00_RS02870	COG0561	phosphatase activity
EYR00_RS02880	COG1876	peptidase activity
EYR00_RS02895	COG1876	peptidase activity
EYR00_RS02900	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
EYR00_RS02905	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EYR00_RS02920	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EYR00_RS02920	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EYR00_RS02920	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYR00_RS02925	COG0383	alpha-mannosidase activity
EYR00_RS02950	COG3706	GGDEF domain
EYR00_RS02955	COG0656	L-ascorbic acid biosynthetic process
EYR00_RS02960	COG0656	L-ascorbic acid biosynthetic process
EYR00_RS02965	COG0656	L-ascorbic acid biosynthetic process
EYR00_RS02975	COG0667	Aldo Keto reductase
EYR00_RS02985	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYR00_RS02990	COG0789	Transcriptional regulator
EYR00_RS03000	COG1321	iron dependent repressor
EYR00_RS03010	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EYR00_RS03020	COG0242	peptide deformylase activity
EYR00_RS03030	COG0454	-acetyltransferase
EYR00_RS03040	COG1272	protein, Hemolysin III
EYR00_RS03065	COG3878	Protein conserved in bacteria
EYR00_RS03075	COG3708	Transcriptional regulator
EYR00_RS03075	COG2207	Transcriptional regulator
EYR00_RS03090	COG0656	L-ascorbic acid biosynthetic process
EYR00_RS03100	COG0488	(ABC) transporter
EYR00_RS03105	COG0463	Glycosyl transferase, family 2
EYR00_RS03115	COG0800	Aldolase
EYR00_RS03140	COG0519	Catalyzes the synthesis of GMP from XMP
EYR00_RS03150	COG2135	peptidase activity
EYR00_RS03155	COG0259	pyridoxamine-phosphate oxidase activity
EYR00_RS03165	COG1125	glycine betaine transport
EYR00_RS03195	COG1063	alcohol dehydrogenase
EYR00_RS03200	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EYR00_RS03205	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EYR00_RS03215	COG0602	queuosine metabolic process
EYR00_RS03220	COG0720	synthase
EYR00_RS03240	COG0673	inositol 2-dehydrogenase activity
EYR00_RS03265	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EYR00_RS03270	COG2723	6-phospho-beta-galactosidase activity
EYR00_RS03280	COG5492	domain, Protein
EYR00_RS03285	COG0446	pyridine nucleotide-disulphide oxidoreductase
EYR00_RS03290	COG2059	Chromate
EYR00_RS03300	COG0583	DNA-binding transcription factor activity
EYR00_RS03305	COG0659	secondary active sulfate transmembrane transporter activity
EYR00_RS03330	COG2195	Cleaves the N-terminal amino acid of tripeptides
EYR00_RS03335	COG0534	Mate efflux family protein
EYR00_RS03380	COG1131	(ABC) transporter
EYR00_RS03410	COG1136	(ABC) transporter
EYR00_RS03420	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EYR00_RS03425	COG2169	Transcriptional regulator
EYR00_RS03430	COG0366	Alpha amylase catalytic
EYR00_RS03435	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EYR00_RS03465	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EYR00_RS03480	COG1773	rubredoxin
EYR00_RS03480	COG0426	domain, Protein
EYR00_RS03490	COG1105	Belongs to the carbohydrate kinase PfkB family
EYR00_RS03495	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYR00_RS03495	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EYR00_RS03495	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EYR00_RS03520	COG2720	vancomycin resistance protein
EYR00_RS03530	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EYR00_RS03535	COG0726	polysaccharide deacetylase
EYR00_RS03545	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYR00_RS03545	COG1263	PTS System
EYR00_RS03545	COG2190	(PTS) system
EYR00_RS03550	COG2723	6-phospho-beta-galactosidase activity
EYR00_RS03565	COG3394	polysaccharide catabolic process
EYR00_RS03570	COG0534	Mate efflux family protein
EYR00_RS03575	COG1268	BioY protein
EYR00_RS03580	COG1752	Esterase of the alpha-beta hydrolase superfamily
EYR00_RS03585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EYR00_RS03590	COG0251	oxidation-reduction process
EYR00_RS03620	COG1131	(ABC) transporter
EYR00_RS03630	COG1725	Transcriptional regulator
EYR00_RS03635	COG1393	Belongs to the ArsC family
EYR00_RS03650	COG0564	pseudouridine synthase activity
EYR00_RS03655	COG0772	Belongs to the SEDS family
EYR00_RS03660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYR00_RS03660	COG2190	(PTS) system
EYR00_RS03660	COG1263	PTS System
EYR00_RS03670	COG2309	aminopeptidase activity
EYR00_RS03680	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EYR00_RS03695	COG2217	Heavy metal translocating P-type atpase
EYR00_RS03700	COG0393	Putative heavy-metal-binding
EYR00_RS03705	COG0564	pseudouridine synthase activity
EYR00_RS03720	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EYR00_RS03740	COG1136	(ABC) transporter
EYR00_RS03765	COG0791	NLP P60 protein
EYR00_RS03765	COG1388	LysM domain
EYR00_RS03795	COG2304	oxidoreductase activity
EYR00_RS03845	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EYR00_RS03845	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EYR00_RS03850	COG2199	diguanylate cyclase activity
EYR00_RS03850	COG2202	Pas domain
EYR00_RS03850	COG2200	EAL domain
EYR00_RS03870	COG0194	GDP metabolic process
EYR00_RS03900	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EYR00_RS03905	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EYR00_RS03905	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EYR00_RS03910	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EYR00_RS03915	COG0631	protein serine/threonine phosphatase activity
EYR00_RS03920	COG2815	serine threonine protein kinase
EYR00_RS03920	COG0515	serine threonine protein kinase
EYR00_RS03925	COG1162	GTPase activity
EYR00_RS03930	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EYR00_RS03935	COG1564	THIamine pyrophosphokinase
EYR00_RS03945	COG2190	(PTS) system
EYR00_RS03950	COG1263	PTS System
EYR00_RS03950	COG2190	(PTS) system
EYR00_RS03950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYR00_RS03955	COG3711	transcriptional antiterminator
EYR00_RS03965	COG1773	rubredoxin
EYR00_RS03965	COG1592	Rubrerythrin
EYR00_RS03980	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EYR00_RS03990	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EYR00_RS03995	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EYR00_RS04000	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EYR00_RS04005	COG3711	transcriptional antiterminator
EYR00_RS04015	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EYR00_RS04020	COG1940	carbohydrate kinase activity
EYR00_RS04050	COG1621	beta-fructofuranosidase activity
EYR00_RS04055	COG1597	lipid kinase activity
EYR00_RS04070	COG1525	nuclease
EYR00_RS04075	COG0601	transmembrane transport
EYR00_RS04080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EYR00_RS04085	COG0444	Belongs to the ABC transporter superfamily
EYR00_RS04090	COG4608	Belongs to the ABC transporter superfamily
EYR00_RS04105	COG0436	Aminotransferase
EYR00_RS04115	COG1215	transferase activity, transferring glycosyl groups
EYR00_RS04120	COG1045	serine acetyltransferase
EYR00_RS04125	COG0671	phosphoesterase, PA-phosphatase related
EYR00_RS04135	COG0628	permease
EYR00_RS04150	COG0789	Transcriptional regulator
EYR00_RS04160	COG1136	(ABC) transporter
EYR00_RS04170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EYR00_RS04175	COG0667	Aldo Keto reductase
EYR00_RS04185	COG0789	Transcriptional regulator
EYR00_RS04220	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EYR00_RS04250	COG1882	Formate acetyltransferase
EYR00_RS04285	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EYR00_RS04295	COG1215	transferase activity, transferring glycosyl groups
EYR00_RS04340	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EYR00_RS04370	COG0667	Aldo Keto reductase
EYR00_RS04405	COG0583	DNA-binding transcription factor activity
EYR00_RS04415	COG2190	(PTS) system
EYR00_RS04415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYR00_RS04415	COG1263	PTS System
EYR00_RS04420	COG2723	6-phospho-beta-galactosidase activity
EYR00_RS04435	COG3715	PTS system
EYR00_RS04440	COG3716	PTS system mannose fructose sorbose family IID component
EYR00_RS04460	COG3588	fructose-bisphosphate aldolase
EYR00_RS04470	COG1132	(ABC) transporter
EYR00_RS04485	COG3142	Participates in the control of copper homeostasis
EYR00_RS04490	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EYR00_RS04505	COG1335	isochorismatase
EYR00_RS04530	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EYR00_RS04555	COG0561	phosphatase activity
EYR00_RS04565	COG3022	response to hydroperoxide
EYR00_RS04575	COG1074	ATP-dependent DNA helicase activity
EYR00_RS04585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EYR00_RS04590	COG1309	transcriptional regulator
EYR00_RS04600	COG0561	phosphatase activity
EYR00_RS04625	COG2382	esterase
EYR00_RS04635	COG3711	transcriptional antiterminator
EYR00_RS04640	COG2190	(PTS) system
EYR00_RS04640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYR00_RS04640	COG1263	PTS System
EYR00_RS04645	COG0613	PHP domain protein
EYR00_RS04655	COG1285	pathogenesis
EYR00_RS04660	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYR00_RS04665	COG2723	6-phospho-beta-galactosidase activity
EYR00_RS04735	COG0656	L-ascorbic acid biosynthetic process
EYR00_RS04745	COG0561	phosphatase activity
EYR00_RS04760	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EYR00_RS04765	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EYR00_RS04770	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EYR00_RS04785	COG1702	phosphate starvation-inducible protein PhoH
EYR00_RS04790	COG0745	RESPONSE REGULATOR receiver
EYR00_RS04795	COG5002	protein histidine kinase activity
EYR00_RS04800	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EYR00_RS04815	COG1803	Methylglyoxal synthase
EYR00_RS04820	COG1396	sequence-specific DNA binding
EYR00_RS04840	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EYR00_RS04860	COG1399	metal-binding, possibly nucleic acid-binding protein
EYR00_RS04865	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EYR00_RS04875	COG0275	rRNA processing
EYR00_RS04890	COG0768	penicillin binding
EYR00_RS04895	COG4536	flavin adenine dinucleotide binding
EYR00_RS04900	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EYR00_RS04915	COG0587	DNA-directed DNA polymerase activity
EYR00_RS04920	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EYR00_RS04920	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EYR00_RS04925	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EYR00_RS04935	COG0237	dephospho-CoA kinase activity
EYR00_RS04940	COG3611	Membrane attachment protein
EYR00_RS04955	COG0469	pyruvate kinase activity
EYR00_RS04980	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EYR00_RS04990	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EYR00_RS04995	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EYR00_RS04995	COG0072	phenylalanine-tRNA ligase activity
EYR00_RS05015	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EYR00_RS05020	COG1323	Belongs to the UPF0348 family
EYR00_RS05055	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EYR00_RS05060	COG0768	penicillin binding
EYR00_RS05070	COG0450	alkyl hydroperoxide reductase
EYR00_RS05075	COG0783	Belongs to the Dps family
EYR00_RS05080	COG1609	Transcriptional regulator
EYR00_RS05085	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EYR00_RS05090	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EYR00_RS05095	COG2017	converts alpha-aldose to the beta-anomer
EYR00_RS05100	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EYR00_RS05105	COG1940	carbohydrate kinase activity
EYR00_RS05125	COG0534	Mate efflux family protein
EYR00_RS05135	COG0469	pyruvate kinase activity
EYR00_RS05140	COG0110	maltose O-acetyltransferase activity
EYR00_RS05155	COG0436	Aminotransferase
EYR00_RS05165	COG2211	Major facilitator Superfamily
EYR00_RS05175	COG1592	Rubrerythrin
EYR00_RS05180	COG2169	Transcriptional regulator
EYR00_RS05185	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EYR00_RS05195	COG2738	Putative neutral zinc metallopeptidase
EYR00_RS05205	COG3935	DnaD domain protein
EYR00_RS05210	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EYR00_RS05215	COG4499	WXG100 protein secretion system (Wss), protein YukC
EYR00_RS05215	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EYR00_RS05220	COG3331	DNA recombination
EYR00_RS05230	COG1396	sequence-specific DNA binding
EYR00_RS05260	COG1454	alcohol dehydrogenase
EYR00_RS05270	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EYR00_RS05275	COG1058	Belongs to the CinA family
EYR00_RS05275	COG1546	Belongs to the CinA family
EYR00_RS05280	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EYR00_RS05295	COG1692	metallophosphoesterase
EYR00_RS05300	COG2359	stage V sporulation protein S
EYR00_RS05310	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EYR00_RS05320	COG0517	IMP dehydrogenase activity
EYR00_RS05320	COG0516	GMP reductase activity
EYR00_RS05330	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EYR00_RS05335	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EYR00_RS05340	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EYR00_RS05345	COG3620	sequence-specific DNA binding
EYR00_RS05350	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EYR00_RS05355	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EYR00_RS05360	COG1490	D-aminoacyl-tRNA deacylase activity
EYR00_RS05380	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EYR00_RS05385	COG0363	glucosamine-6-phosphate deaminase activity
EYR00_RS05390	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EYR00_RS05445	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EYR00_RS05455	COG2183	response to ionizing radiation
EYR00_RS05465	COG1959	2 iron, 2 sulfur cluster binding
EYR00_RS05475	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EYR00_RS05480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EYR00_RS05485	COG0205	6-phosphofructokinase activity
EYR00_RS05500	COG0347	Belongs to the P(II) protein family
EYR00_RS05505	COG0004	ammonium transporteR
EYR00_RS05510	COG2873	o-acetylhomoserine
EYR00_RS05540	COG0772	Belongs to the SEDS family
EYR00_RS05560	COG0742	ribosomal rna small subunit methyltransferase
EYR00_RS05565	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EYR00_RS05570	COG0540	Belongs to the ATCase OTCase family
EYR00_RS05580	COG0543	2 iron, 2 sulfur cluster binding
EYR00_RS05585	COG0167	dihydroorotate dehydrogenase activity
EYR00_RS05600	COG0210	DNA helicase
EYR00_RS05605	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EYR00_RS05620	COG0154	amidase activity
EYR00_RS05625	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EYR00_RS05650	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EYR00_RS05670	COG0110	maltose O-acetyltransferase activity
EYR00_RS05715	COG2723	6-phospho-beta-galactosidase activity
EYR00_RS05725	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EYR00_RS05730	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EYR00_RS05735	COG1136	(ABC) transporter
EYR00_RS05755	COG1132	(ABC) transporter
EYR00_RS05775	COG1132	(ABC) transporter
EYR00_RS05790	COG0588	phosphoglycerate mutase activity
EYR00_RS05805	COG0544	peptidyl-prolyl cis-trans isomerase activity
EYR00_RS05815	COG1028	Short-chain dehydrogenase reductase Sdr
EYR00_RS05820	COG3835	regulator
EYR00_RS05825	COG1929	Belongs to the glycerate kinase type-1 family
EYR00_RS05835	COG0561	phosphatase activity
EYR00_RS05860	COG0561	phosphatase activity
EYR00_RS05875	COG3022	response to hydroperoxide
EYR00_RS05880	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EYR00_RS05885	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EYR00_RS05900	COG2239	Acts as a magnesium transporter
EYR00_RS05925	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EYR00_RS05940	COG3859	Proton-coupled thiamine transporter YuaJ
EYR00_RS05945	COG3557	Belongs to the UPF0374 family
EYR00_RS05950	COG0802	atpase or kinase
EYR00_RS05955	COG1214	PFAM Peptidase M22, glycoprotease
EYR00_RS05965	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EYR00_RS05970	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EYR00_RS05975	COG0017	Asparaginyl-tRNA synthetase
EYR00_RS05985	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EYR00_RS05995	COG0733	neurotransmitter:sodium symporter activity
EYR00_RS06000	COG0700	Nucleoside recognition
EYR00_RS06005	COG2715	membrane protein required for spore maturation
EYR00_RS06010	COG1686	Belongs to the peptidase S11 family
EYR00_RS06020	COG1187	pseudouridine synthase activity
EYR00_RS06030	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EYR00_RS06035	COG1940	carbohydrate kinase activity
EYR00_RS06045	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EYR00_RS06050	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EYR00_RS06065	COG5658	integral membrane protein
EYR00_RS06080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYR00_RS06085	COG0800	Aldolase
EYR00_RS06090	COG0129	dihydroxy-acid dehydratase activity
EYR00_RS06095	COG2186	Transcriptional regulator
EYR00_RS06105	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EYR00_RS06105	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
EYR00_RS06125	COG2199	diguanylate cyclase activity
EYR00_RS06125	COG2203	Gaf domain
EYR00_RS06135	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EYR00_RS06145	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EYR00_RS06150	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EYR00_RS06155	COG1605	Chorismate mutase
EYR00_RS06155	COG0077	Prephenate dehydratase
EYR00_RS06165	COG3706	GGDEF domain
EYR00_RS06175	COG0420	3'-5' exonuclease activity
EYR00_RS06180	COG0419	ATPase involved in DNA repair
EYR00_RS06185	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EYR00_RS06195	COG0534	Mate efflux family protein
EYR00_RS06200	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EYR00_RS06225	COG2252	PERMEase
EYR00_RS06230	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
EYR00_RS06235	COG0708	Exodeoxyribonuclease III
EYR00_RS06240	COG0733	neurotransmitter:sodium symporter activity
EYR00_RS06270	COG2508	Transcriptional regulator
EYR00_RS06285	COG0494	nUDIX hydrolase
EYR00_RS06295	COG3711	transcriptional antiterminator
EYR00_RS06295	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYR00_RS06305	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EYR00_RS06310	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EYR00_RS06315	COG0383	alpha-mannosidase activity
EYR00_RS06350	COG1518	maintenance of DNA repeat elements
EYR00_RS06355	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EYR00_RS06375	COG0574	Belongs to the PEP-utilizing enzyme family
EYR00_RS06375	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EYR00_RS06380	COG0252	asparaginase activity
EYR00_RS06395	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EYR00_RS06405	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EYR00_RS06405	COG1013	pyruvate-flavodoxin oxidoreductase activity
EYR00_RS06405	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EYR00_RS06405	COG0674	pyruvate-flavodoxin oxidoreductase activity
EYR00_RS06440	COG3481	metal-dependent phosphohydrolase, HD sub domain
EYR00_RS06450	COG0537	adenosine 5'-monophosphoramidase activity
EYR00_RS06470	COG1272	protein, Hemolysin III
EYR00_RS06480	COG0396	ATPase activity
EYR00_RS06485	COG0719	Fe-S assembly protein
EYR00_RS06490	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EYR00_RS06505	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EYR00_RS06515	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EYR00_RS06560	COG0166	Belongs to the GPI family
EYR00_RS06565	COG1098	S1 RNA binding domain
EYR00_RS06570	COG5001	Diguanylate cyclase
EYR00_RS06575	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EYR00_RS06580	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EYR00_RS06590	COG1242	4 iron, 4 sulfur cluster binding
EYR00_RS06595	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EYR00_RS06600	COG1136	(ABC) transporter
EYR00_RS06605	COG0495	leucyl-tRNA aminoacylation
EYR00_RS06615	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EYR00_RS06625	COG4657	Part of a membrane complex involved in electron transport
EYR00_RS06630	COG4660	Part of a membrane complex involved in electron transport
EYR00_RS06635	COG4659	FMN binding
EYR00_RS06640	COG4658	electron transport chain
EYR00_RS06645	COG4656	Part of a membrane complex involved in electron transport
EYR00_RS06665	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EYR00_RS06670	COG0284	orotidine-5'-phosphate decarboxylase activity
EYR00_RS06675	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EYR00_RS06680	COG1682	transport, permease protein
EYR00_RS06685	COG1134	teichoic acid transport
EYR00_RS06690	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EYR00_RS06695	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EYR00_RS06695	COG0463	Glycosyl transferase, family 2
EYR00_RS06710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EYR00_RS06715	COG2337	Toxic component of a toxin-antitoxin (TA) module
EYR00_RS06760	COG0494	nUDIX hydrolase
EYR00_RS06765	COG0564	pseudouridine synthase activity
EYR00_RS06775	COG0482	sulfurtransferase activity
EYR00_RS06780	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EYR00_RS06790	COG4472	Bacterial protein of unknown function (DUF965)
EYR00_RS06795	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EYR00_RS06800	COG3906	Belongs to the UPF0473 family
EYR00_RS06805	COG2706	6-phosphogluconolactonase activity
EYR00_RS06810	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EYR00_RS06815	COG4122	O-methyltransferase activity
EYR00_RS06830	COG0572	uridine kinase
EYR00_RS06845	COG2323	membrane
EYR00_RS06850	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EYR00_RS06855	COG4120	Belongs to the binding-protein-dependent transport system permease family
EYR00_RS06880	COG1185	polyribonucleotide nucleotidyltransferase activity
EYR00_RS06890	COG0789	Transcriptional regulator
EYR00_RS06900	COG0577	efflux transmembrane transporter activity
EYR00_RS06905	COG1136	(ABC) transporter
EYR00_RS06915	COG2723	6-phospho-beta-galactosidase activity
EYR00_RS06925	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EYR00_RS06925	COG1918	ferrous iron import across plasma membrane
EYR00_RS06930	COG1918	ferrous iron import across plasma membrane
EYR00_RS06930	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EYR00_RS06965	COG0784	Response regulator, receiver
EYR00_RS06965	COG3437	response regulator, receiver
EYR00_RS06970	COG0778	Nitroreductase
EYR00_RS06980	COG1937	Protein conserved in bacteria
EYR00_RS06990	COG0704	Plays a role in the regulation of phosphate uptake
EYR00_RS06995	COG1132	(ABC) transporter
EYR00_RS07035	COG1472	Belongs to the glycosyl hydrolase 3 family
EYR00_RS07045	COG0561	phosphatase activity
EYR00_RS07065	COG1126	abc transporter atp-binding protein
EYR00_RS07070	COG0436	Aminotransferase
EYR00_RS07075	COG2244	polysaccharide biosynthetic process
EYR00_RS07085	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EYR00_RS07085	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EYR00_RS07090	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EYR00_RS07095	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EYR00_RS07100	COG0124	histidyl-tRNA synthetase
EYR00_RS07130	COG1609	Transcriptional regulator
EYR00_RS07135	COG1595	DNA-templated transcription, initiation
EYR00_RS07150	COG0037	tRNA processing
EYR00_RS07155	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EYR00_RS07160	COG0196	riboflavin kinase activity
EYR00_RS07170	COG2084	Dehydrogenase
EYR00_RS07175	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EYR00_RS07195	COG0301	tRNA thio-modification
EYR00_RS07210	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EYR00_RS07215	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EYR00_RS07225	COG0745	RESPONSE REGULATOR receiver
EYR00_RS07230	COG5002	protein histidine kinase activity
EYR00_RS07235	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EYR00_RS07240	COG1196	nuclear chromosome segregation
EYR00_RS07245	COG0552	protein localization to endoplasmic reticulum
EYR00_RS07250	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EYR00_RS07255	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EYR00_RS07260	COG0500	methyltransferase
EYR00_RS07265	COG0228	four-way junction DNA binding
EYR00_RS07280	COG0336	Belongs to the RNA methyltransferase TrmD family
EYR00_RS07285	COG0335	large ribosomal subunit rRNA binding
EYR00_RS07290	COG0681	Belongs to the peptidase S26 family
EYR00_RS07300	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EYR00_RS07305	COG0758	DNA mediated transformation
EYR00_RS07310	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EYR00_RS07315	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EYR00_RS07320	COG4974	Belongs to the 'phage' integrase family
EYR00_RS07325	COG0052	Belongs to the universal ribosomal protein uS2 family
EYR00_RS07330	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EYR00_RS07335	COG0528	UMP kinase activity
EYR00_RS07340	COG0233	cytoplasmic translational termination
EYR00_RS07355	COG4589	Belongs to the CDS family
EYR00_RS07360	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EYR00_RS07370	COG2176	DNA-directed DNA polymerase activity
EYR00_RS07375	COG0779	Required for maturation of 30S ribosomal subunits
EYR00_RS07380	COG0195	Participates in both transcription termination and antitermination
EYR00_RS07385	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EYR00_RS07390	COG1358	cellular component organization or biogenesis
EYR00_RS07395	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EYR00_RS07400	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EYR00_RS07430	COG1187	pseudouridine synthase activity
EYR00_RS07435	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EYR00_RS07440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYR00_RS07445	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EYR00_RS07455	COG0736	holo-[acyl-carrier-protein] synthase activity
EYR00_RS07465	COG2203	Gaf domain
EYR00_RS07465	COG2199	diguanylate cyclase activity
EYR00_RS07475	COG0481	GTPase activity
EYR00_RS07480	COG2723	6-phospho-beta-galactosidase activity
EYR00_RS07490	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EYR00_RS07495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EYR00_RS07500	COG2801	Transposase and inactivated derivatives
EYR00_RS07505	COG2801	Transposase and inactivated derivatives
EYR00_RS07520	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EYR00_RS07555	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EYR00_RS07570	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EYR00_RS07575	COG1570	exodeoxyribonuclease VII activity
EYR00_RS07580	COG1722	exodeoxyribonuclease VII activity
EYR00_RS07590	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EYR00_RS07595	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EYR00_RS07600	COG0497	DNA recombination
EYR00_RS07605	COG0750	zinc metalloprotease
EYR00_RS07610	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EYR00_RS07615	COG1687	branched-chain amino acid
EYR00_RS07620	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EYR00_RS07630	COG4974	Belongs to the 'phage' integrase family
EYR00_RS07695	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EYR00_RS07710	COG2848	UPF0210 protein
EYR00_RS07745	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EYR00_RS07750	COG2226	methyltransferase
EYR00_RS07755	COG0799	negative regulation of ribosome biogenesis
EYR00_RS07760	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EYR00_RS07760	COG1713	HD superfamily hydrolase involved in NAD metabolism
EYR00_RS07765	COG1534	Rna-binding protein
EYR00_RS07770	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EYR00_RS07780	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EYR00_RS07785	COG0187	DNA topoisomerase II activity
EYR00_RS07790	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EYR00_RS07795	COG0406	alpha-ribazole phosphatase activity
EYR00_RS07800	COG3763	UPF0154 protein
EYR00_RS07810	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EYR00_RS07820	COG0612	Peptidase, M16
EYR00_RS07845	COG1744	ABC transporter substrate-binding protein PnrA-like
EYR00_RS07850	COG1674	ftsk spoiiie
EYR00_RS07855	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EYR00_RS07865	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EYR00_RS07870	COG0527	aspartate kinase activity
EYR00_RS07880	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EYR00_RS07895	COG1773	rubredoxin
EYR00_RS07895	COG1592	Rubrerythrin
EYR00_RS07900	COG0693	protein deglycase activity
EYR00_RS07905	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EYR00_RS07935	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EYR00_RS07935	COG1918	ferrous iron import across plasma membrane
EYR00_RS07940	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EYR00_RS07940	COG1918	ferrous iron import across plasma membrane
EYR00_RS07945	COG1234	tRNA 3'-trailer cleavage
EYR00_RS07950	COG2217	Heavy metal translocating P-type atpase
EYR00_RS07970	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EYR00_RS07975	COG0372	Belongs to the citrate synthase family
EYR00_RS07980	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EYR00_RS07995	COG1956	GAF domain-containing protein
EYR00_RS08010	COG0726	polysaccharide deacetylase
EYR00_RS08015	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EYR00_RS08030	COG1132	(ABC) transporter
EYR00_RS08035	COG1132	(ABC) transporter
EYR00_RS08040	COG1846	Transcriptional regulator
EYR00_RS08075	COG0534	Mate efflux family protein
EYR00_RS08080	COG1129	ABC transporter
EYR00_RS08085	COG0488	(ABC) transporter
EYR00_RS08090	COG0488	(ABC) transporter
EYR00_RS08095	COG1748	Saccharopine dehydrogenase
EYR00_RS08110	COG0275	rRNA processing
EYR00_RS08120	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EYR00_RS08130	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EYR00_RS08160	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EYR00_RS08180	COG0519	Catalyzes the synthesis of GMP from XMP
EYR00_RS08180	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EYR00_RS08185	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EYR00_RS08190	COG0583	DNA-binding transcription factor activity
EYR00_RS08195	COG1461	Dihydroxyacetone kinase
EYR00_RS08200	COG1546	Belongs to the CinA family
EYR00_RS08200	COG1058	Belongs to the CinA family
EYR00_RS08215	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EYR00_RS08220	COG1132	(ABC) transporter
EYR00_RS08230	COG1846	Transcriptional regulator
EYR00_RS08245	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EYR00_RS08250	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EYR00_RS08270	COG2249	NAD(P)H dehydrogenase (quinone) activity
EYR00_RS08285	COG0656	L-ascorbic acid biosynthetic process
EYR00_RS08295	COG0583	DNA-binding transcription factor activity
EYR00_RS08300	COG3681	Belongs to the UPF0597 family
EYR00_RS08320	COG0561	phosphatase activity
EYR00_RS08330	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EYR00_RS08335	COG0151	Belongs to the GarS family
EYR00_RS08340	COG0138	bifunctional purine biosynthesis protein purh
EYR00_RS08345	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EYR00_RS08350	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EYR00_RS08355	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EYR00_RS08360	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EYR00_RS08365	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EYR00_RS08400	COG0789	Transcriptional regulator
EYR00_RS08410	COG1780	Probably involved in ribonucleotide reductase function
EYR00_RS08415	COG0148	phosphopyruvate hydratase activity
EYR00_RS08440	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EYR00_RS08445	COG2723	6-phospho-beta-galactosidase activity
EYR00_RS08460	COG1733	regulation of RNA biosynthetic process
EYR00_RS08500	COG2723	6-phospho-beta-galactosidase activity
EYR00_RS08505	COG1737	Transcriptional regulator
EYR00_RS08520	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EYR00_RS08540	COG0561	phosphatase activity
EYR00_RS08565	COG0667	Aldo Keto reductase
EYR00_RS08570	COG1028	Short-chain dehydrogenase reductase Sdr
EYR00_RS08585	COG0583	DNA-binding transcription factor activity
EYR00_RS08590	COG2723	6-phospho-beta-galactosidase activity
EYR00_RS08595	COG2207	Transcriptional regulator
EYR00_RS08595	COG1917	Cupin 2, conserved barrel domain protein
EYR00_RS08600	COG1940	carbohydrate kinase activity
EYR00_RS08605	COG2723	6-phospho-beta-galactosidase activity
EYR00_RS08610	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYR00_RS08615	COG1136	(ABC) transporter
EYR00_RS08615	COG0577	efflux transmembrane transporter activity
EYR00_RS08635	COG1131	(ABC) transporter
EYR00_RS08640	COG1486	melibiose metabolic process
EYR00_RS08645	COG0363	glucosamine-6-phosphate deaminase activity
EYR00_RS08650	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYR00_RS08660	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYR00_RS08660	COG3711	transcriptional antiterminator
EYR00_RS08685	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EYR00_RS08700	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EYR00_RS08705	COG0588	phosphoglycerate mutase activity
EYR00_RS08710	COG0667	Aldo Keto reductase
EYR00_RS08730	COG4978	Transcriptional regulator
EYR00_RS08730	COG0789	Transcriptional regulator
EYR00_RS08740	COG0583	DNA-binding transcription factor activity
EYR00_RS08750	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EYR00_RS08765	COG0789	Transcriptional regulator
EYR00_RS08775	COG0583	DNA-binding transcription factor activity
EYR00_RS08780	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYR00_RS08795	COG3773	Cell wall hydrolase
EYR00_RS08815	COG1362	aminopeptidase activity
EYR00_RS08820	COG0531	amino acid
EYR00_RS08825	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EYR00_RS08840	COG1160	GTP binding
EYR00_RS08850	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EYR00_RS08860	COG1737	Transcriptional regulator
EYR00_RS08885	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EYR00_RS08890	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EYR00_RS08900	COG0456	acetyltransferase
EYR00_RS08905	COG2378	regulation of single-species biofilm formation
EYR00_RS08925	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EYR00_RS08930	COG1464	Belongs to the NlpA lipoprotein family
EYR00_RS08935	COG2011	ABC-type metal ion transport system permease component
EYR00_RS08960	COG1476	TRANSCRIPTIONal
EYR00_RS08970	COG4555	ABC transporter
EYR00_RS08975	COG1668	transmembrane transport
EYR00_RS08980	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EYR00_RS08990	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EYR00_RS08995	COG0140	phosphoribosyl-ATP diphosphatase activity
EYR00_RS08995	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EYR00_RS09000	COG0107	imidazoleglycerol-phosphate synthase activity
EYR00_RS09010	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EYR00_RS09020	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EYR00_RS09025	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EYR00_RS09030	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EYR00_RS09035	COG0745	RESPONSE REGULATOR receiver
EYR00_RS09075	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EYR00_RS09080	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EYR00_RS09195	COG1177	transmembrane transport
EYR00_RS09200	COG1176	ABC-type spermidine putrescine transport system, permease component I
EYR00_RS09205	COG3842	ATPase activity
EYR00_RS09210	COG1396	sequence-specific DNA binding
EYR00_RS09225	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EYR00_RS09235	COG0571	ribonuclease III activity
EYR00_RS09240	COG0416	fatty acid biosynthetic process
EYR00_RS09245	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EYR00_RS09255	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYR00_RS09260	COG3711	transcriptional antiterminator
EYR00_RS09265	COG1263	PTS System
EYR00_RS09265	COG2190	(PTS) system
EYR00_RS09265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYR00_RS09280	COG3408	Glycogen debranching enzyme
EYR00_RS09280	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
EYR00_RS09295	COG0583	DNA-binding transcription factor activity
EYR00_RS09300	COG0534	Mate efflux family protein
EYR00_RS09305	COG0582	viral genome integration into host DNA
EYR00_RS09315	COG1461	Dihydroxyacetone kinase
EYR00_RS09320	COG1302	Protein conserved in bacteria
EYR00_RS09325	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EYR00_RS09330	COG2723	6-phospho-beta-galactosidase activity
EYR00_RS09350	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EYR00_RS09355	COG1420	regulation of RNA biosynthetic process
EYR00_RS09360	COG1773	rubredoxin
EYR00_RS09360	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EYR00_RS09365	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EYR00_RS09370	COG1760	l-serine dehydratase
EYR00_RS09375	COG1466	dna polymerase III delta subunit
EYR00_RS09380	COG2333	competence protein COMEC
EYR00_RS09380	COG0658	competence protein
EYR00_RS09385	COG1596	polysaccharide export
EYR00_RS09385	COG1555	photosystem II stabilization
EYR00_RS09390	COG2255	four-way junction helicase activity
EYR00_RS09395	COG0632	four-way junction helicase activity
EYR00_RS09400	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EYR00_RS09405	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EYR00_RS09420	COG1994	Peptidase M50
EYR00_RS09430	COG2894	cell division
EYR00_RS09435	COG0850	regulation of cytokinetic process
EYR00_RS09445	COG1792	Involved in formation and maintenance of cell shape
EYR00_RS09450	COG2003	Belongs to the UPF0758 family
EYR00_RS09490	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EYR00_RS09495	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EYR00_RS09500	COG0544	peptidyl-prolyl cis-trans isomerase activity
EYR00_RS09510	COG0583	DNA-binding transcription factor activity
EYR00_RS09515	COG2855	membrane
EYR00_RS09520	COG3231	kanamycin kinase activity
EYR00_RS09530	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EYR00_RS09530	COG1713	HD superfamily hydrolase involved in NAD metabolism
EYR00_RS09555	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EYR00_RS09560	COG1876	peptidase activity
EYR00_RS09565	COG2197	response regulator
EYR00_RS09570	COG0322	excinuclease ABC activity
EYR00_RS09575	COG1193	negative regulation of DNA recombination
EYR00_RS09595	COG0564	pseudouridine synthase activity
EYR00_RS09600	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EYR00_RS09610	COG1272	protein, Hemolysin III
EYR00_RS09620	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EYR00_RS09630	COG1410	methionine synthase
EYR00_RS09630	COG0646	methionine synthase
EYR00_RS09650	COG0667	Aldo Keto reductase
EYR00_RS09660	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EYR00_RS09665	COG1597	lipid kinase activity
EYR00_RS09695	COG0494	nUDIX hydrolase
EYR00_RS09700	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EYR00_RS09735	COG2172	sigma factor antagonist activity
EYR00_RS09780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EYR00_RS09785	COG3706	GGDEF domain
EYR00_RS09795	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EYR00_RS09805	COG0697	spore germination
EYR00_RS09815	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EYR00_RS09830	COG3263	regulation of cellular component size
EYR00_RS09835	COG0285	dihydrofolate synthase activity
EYR00_RS09840	COG3870	Protein conserved in bacteria
EYR00_RS09845	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EYR00_RS09855	COG0569	domain protein
EYR00_RS09860	COG0569	domain protein
EYR00_RS09865	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EYR00_RS09870	COG1971	Probably functions as a manganese efflux pump
EYR00_RS09875	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
EYR00_RS09880	COG2081	HI0933 family
EYR00_RS09885	COG0217	transcriptional regulatory protein
EYR00_RS09895	COG0824	Thioesterase
EYR00_RS09900	COG0346	lactoylglutathione lyase activity
EYR00_RS09905	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EYR00_RS09915	COG1482	cell wall glycoprotein biosynthetic process
EYR00_RS09925	COG0546	phosphoglycolate phosphatase activity
EYR00_RS09935	COG1959	2 iron, 2 sulfur cluster binding
EYR00_RS09940	COG1511	domain protein
EYR00_RS09945	COG1686	Belongs to the peptidase S11 family
EYR00_RS09950	COG0697	spore germination
EYR00_RS09955	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EYR00_RS09970	COG1799	cell septum assembly
EYR00_RS09980	COG1191	sigma factor activity
EYR00_RS09985	COG1191	sigma factor activity
EYR00_RS09995	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EYR00_RS10000	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EYR00_RS10005	COG0849	cell division
EYR00_RS10010	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EYR00_RS10015	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EYR00_RS10025	COG0772	Belongs to the SEDS family
EYR00_RS10050	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EYR00_RS10070	COG2723	6-phospho-beta-galactosidase activity
EYR00_RS10075	COG0534	Mate efflux family protein
EYR00_RS10080	COG2723	6-phospho-beta-galactosidase activity
EYR00_RS10110	COG0745	RESPONSE REGULATOR receiver
EYR00_RS10115	COG2205	protein histidine kinase activity
EYR00_RS10125	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EYR00_RS10130	COG0159	tryptophan synthase activity
EYR00_RS10135	COG0133	tryptophan synthase activity
EYR00_RS10145	COG0134	indole-3-glycerol-phosphate synthase activity
EYR00_RS10150	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EYR00_RS10155	COG0512	Glutamine amidotransferase of anthranilate synthase
EYR00_RS10155	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EYR00_RS10170	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EYR00_RS10180	COG0697	spore germination
EYR00_RS10185	COG2207	Transcriptional regulator
EYR00_RS10185	COG1917	Cupin 2, conserved barrel domain protein
EYR00_RS10190	COG0583	DNA-binding transcription factor activity
EYR00_RS10200	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EYR00_RS10220	COG1357	PFAM Pentapeptide repeats (8 copies)
EYR00_RS10230	COG1091	dTDP-4-dehydrorhamnose reductase activity
EYR00_RS10250	COG0726	polysaccharide deacetylase
EYR00_RS10285	COG1686	Belongs to the peptidase S11 family
EYR00_RS10305	COG0489	protein tyrosine kinase activity
EYR00_RS10355	COG0561	phosphatase activity
EYR00_RS10390	COG0268	Binds directly to 16S ribosomal RNA
EYR00_RS10395	COG1164	Oligoendopeptidase f
EYR00_RS10405	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EYR00_RS10420	COG0513	Belongs to the DEAD box helicase family
EYR00_RS10430	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EYR00_RS10435	COG0534	Mate efflux family protein
EYR00_RS10450	COG2384	SAM-dependent methyltransferase
EYR00_RS10455	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EYR00_RS10460	COG0358	DNA primase activity
EYR00_RS10465	COG0423	glycine-tRNA ligase activity
EYR00_RS10485	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EYR00_RS10490	COG0295	cytidine deaminase activity
EYR00_RS10495	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EYR00_RS10500	COG1132	(ABC) transporter
EYR00_RS10515	COG3266	domain, Protein
EYR00_RS10515	COG4932	domain protein
EYR00_RS10515	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
EYR00_RS10550	COG1459	type II secretion system
EYR00_RS10565	COG2059	Chromate
EYR00_RS10570	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EYR00_RS10580	COG2171	N-acyltransferase activity
EYR00_RS10585	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EYR00_RS10600	COG1132	(ABC) transporter
EYR00_RS10605	COG1132	(ABC) transporter
EYR00_RS10615	COG0778	Nitroreductase
EYR00_RS10620	COG0488	(ABC) transporter
EYR00_RS10625	COG3546	catalase activity
EYR00_RS10660	COG0789	Transcriptional regulator
EYR00_RS10660	COG4978	Transcriptional regulator
EYR00_RS10665	COG0488	(ABC) transporter
EYR00_RS10670	COG1073	alpha beta
EYR00_RS10685	COG2177	Part of the ABC transporter FtsEX involved in
EYR00_RS10690	COG2884	Cell division ATP-binding protein ftsE
EYR00_RS10700	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EYR00_RS10705	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EYR00_RS10710	COG0653	protein targeting
EYR00_RS10715	COG1278	Cold shock
EYR00_RS10720	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EYR00_RS10740	COG0492	ferredoxin-NADP+ reductase activity
EYR00_RS10745	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYR00_RS10760	COG1854	S-ribosylhomocysteine lyase activity
EYR00_RS10765	COG1307	EDD domain protein, DegV family
EYR00_RS10770	COG1739	Uncharacterized protein family UPF0029
EYR00_RS10790	COG1309	transcriptional regulator
EYR00_RS10795	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EYR00_RS10805	COG1523	belongs to the glycosyl hydrolase 13 family
EYR00_RS10810	COG0058	SHG alpha-glucan phosphorylase activity
EYR00_RS10820	COG1609	Transcriptional regulator
EYR00_RS10830	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYR00_RS10835	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EYR00_RS10845	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EYR00_RS10860	COG5426	von Willebrand factor, type A
EYR00_RS10865	COG3842	ATPase activity
EYR00_RS10875	COG0395	ABC-type sugar transport system, permease component
EYR00_RS10880	COG1175	transmembrane transport
EYR00_RS10890	COG2207	Transcriptional regulator
EYR00_RS10890	COG1917	Cupin 2, conserved barrel domain protein
EYR00_RS10910	COG1122	ATPase activity
EYR00_RS10960	COG1136	(ABC) transporter
EYR00_RS10965	COG5002	protein histidine kinase activity
EYR00_RS10970	COG0745	RESPONSE REGULATOR receiver
EYR00_RS10985	COG1132	(ABC) transporter
EYR00_RS10990	COG1132	(ABC) transporter
EYR00_RS11000	COG3716	PTS system mannose fructose sorbose family IID component
EYR00_RS11025	COG2197	response regulator
EYR00_RS11030	COG4585	Histidine kinase
EYR00_RS11040	COG1621	beta-fructofuranosidase activity
EYR00_RS11045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYR00_RS11045	COG1263	PTS System
EYR00_RS11050	COG1609	Transcriptional regulator
EYR00_RS11060	COG2723	6-phospho-beta-galactosidase activity
EYR00_RS11065	COG0527	aspartate kinase activity
EYR00_RS11105	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EYR00_RS11115	COG0446	pyridine nucleotide-disulphide oxidoreductase
EYR00_RS11130	COG2723	6-phospho-beta-galactosidase activity
EYR00_RS11145	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EYR00_RS11150	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EYR00_RS11155	COG2723	6-phospho-beta-galactosidase activity
EYR00_RS11160	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EYR00_RS11170	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EYR00_RS11185	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EYR00_RS11220	COG1459	type II secretion system
EYR00_RS11225	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EYR00_RS11240	COG4868	Belongs to the UPF0371 family
EYR00_RS11245	COG0366	Alpha amylase catalytic
EYR00_RS11250	COG1263	PTS System
EYR00_RS11250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYR00_RS11255	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EYR00_RS11260	COG2188	Transcriptional regulator
EYR00_RS11265	COG0561	phosphatase activity
EYR00_RS11270	COG1363	Peptidase, m42
EYR00_RS11285	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EYR00_RS11300	COG4808	Protein conserved in bacteria
EYR00_RS11310	COG3118	belongs to the thioredoxin family
EYR00_RS11325	COG1131	(ABC) transporter
EYR00_RS11330	COG2188	Transcriptional regulator
EYR00_RS11340	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EYR00_RS11345	COG1408	metallophosphoesterase
EYR00_RS11350	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EYR00_RS11355	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EYR00_RS11360	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EYR00_RS11370	COG1131	(ABC) transporter
EYR00_RS11375	COG0628	permease
EYR00_RS11380	COG0137	argininosuccinate synthase activity
EYR00_RS11385	COG0165	Argininosuccinate lyase
EYR00_RS11455	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EYR00_RS11465	COG0561	phosphatase activity
EYR00_RS11475	COG1592	Rubrerythrin
EYR00_RS11495	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EYR00_RS11500	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EYR00_RS11515	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EYR00_RS11530	COG2116	formate transmembrane transporter activity
EYR00_RS11550	COG0459	protein refolding
EYR00_RS11560	COG0534	Mate efflux family protein
EYR00_RS11565	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYR00_RS11565	COG2190	(PTS) system
EYR00_RS11565	COG1263	PTS System
EYR00_RS11580	COG1263	PTS System
EYR00_RS11580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYR00_RS11590	COG0698	ribose 5-phosphate isomerase
EYR00_RS11595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYR00_RS11595	COG1263	PTS System
EYR00_RS11595	COG2190	(PTS) system
EYR00_RS11605	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EYR00_RS11610	COG1263	PTS System
EYR00_RS11610	COG2190	(PTS) system
EYR00_RS11610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYR00_RS11615	COG1609	Transcriptional regulator
EYR00_RS11620	COG1737	Transcriptional regulator
EYR00_RS11625	COG1486	melibiose metabolic process
EYR00_RS11635	COG3706	GGDEF domain
EYR00_RS11695	COG0561	phosphatase activity
EYR00_RS11705	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EYR00_RS11715	COG1882	Formate acetyltransferase
EYR00_RS11720	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EYR00_RS11725	COG1349	DNA-binding transcription factor activity
EYR00_RS11730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EYR00_RS11735	COG1013	pyruvate-flavodoxin oxidoreductase activity
EYR00_RS11745	COG0561	phosphatase activity
EYR00_RS11750	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EYR00_RS11770	COG0534	Mate efflux family protein
EYR00_RS11775	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
EYR00_RS11780	COG1691	(AIR) carboxylase
EYR00_RS11785	COG1122	ATPase activity
EYR00_RS11795	COG0310	cobalt ion transport
EYR00_RS11805	COG1606	tRNA processing
EYR00_RS11810	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EYR00_RS11830	COG3711	transcriptional antiterminator
EYR00_RS11830	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYR00_RS11840	COG1486	melibiose metabolic process
EYR00_RS11845	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYR00_RS11885	COG0438	transferase activity, transferring glycosyl groups
EYR00_RS11890	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EYR00_RS11905	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EYR00_RS11920	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EYR00_RS11925	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EYR00_RS11930	COG4120	Belongs to the binding-protein-dependent transport system permease family
EYR00_RS11955	COG0714	Associated with various cellular activities
EYR00_RS11960	COG0733	neurotransmitter:sodium symporter activity
EYR00_RS11975	COG0583	DNA-binding transcription factor activity
EYR00_RS11990	COG0488	(ABC) transporter
EYR00_RS11995	COG0656	L-ascorbic acid biosynthetic process
EYR00_RS12005	COG0656	L-ascorbic acid biosynthetic process
EYR00_RS12020	COG0583	DNA-binding transcription factor activity
EYR00_RS12035	COG0561	phosphatase activity
EYR00_RS12040	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYR00_RS12075	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EYR00_RS12080	COG0557	exoribonuclease II activity
EYR00_RS12095	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EYR00_RS12105	COG0561	phosphatase activity
EYR00_RS12125	COG1737	Transcriptional regulator
EYR00_RS12160	COG2385	sporulation resulting in formation of a cellular spore
EYR00_RS12170	COG4989	oxidoreductase activity
EYR00_RS12185	COG0577	efflux transmembrane transporter activity
EYR00_RS12185	COG1136	(ABC) transporter
EYR00_RS12215	COG1876	peptidase activity
EYR00_RS12230	COG0745	RESPONSE REGULATOR receiver
EYR00_RS12240	COG1131	(ABC) transporter
EYR00_RS12290	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EYR00_RS12305	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EYR00_RS12310	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EYR00_RS12315	COG2155	Conserved Protein
EYR00_RS12325	COG0813	purine-nucleoside phosphorylase activity
EYR00_RS12345	COG1131	(ABC) transporter
EYR00_RS12355	COG1472	Belongs to the glycosyl hydrolase 3 family
EYR00_RS12360	COG2188	Transcriptional regulator
EYR00_RS12385	COG1737	Transcriptional regulator
EYR00_RS12400	COG1486	melibiose metabolic process
EYR00_RS12410	COG1263	PTS System
EYR00_RS12410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYR00_RS12415	COG0367	asparagine synthase
EYR00_RS12430	COG1940	carbohydrate kinase activity
EYR00_RS12440	COG1131	(ABC) transporter
EYR00_RS12455	COG1394	ATPase activity, coupled to movement of substances
EYR00_RS12485	COG1269	ATP hydrolysis coupled proton transport
EYR00_RS12515	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EYR00_RS12555	COG1307	EDD domain protein, DegV family
EYR00_RS12570	COG1486	melibiose metabolic process
EYR00_RS12580	COG1704	LemA family
EYR00_RS12585	COG3250	beta-galactosidase activity
EYR00_RS12620	COG2723	6-phospho-beta-galactosidase activity
EYR00_RS12625	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYR00_RS12680	COG1263	PTS System
EYR00_RS12680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYR00_RS12680	COG2190	(PTS) system
EYR00_RS12685	COG3711	transcriptional antiterminator
EYR00_RS12690	COG2190	(PTS) system
EYR00_RS12690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYR00_RS12690	COG1263	PTS System
EYR00_RS12700	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EYR00_RS12755	COG0386	Belongs to the glutathione peroxidase family
EYR00_RS12770	COG0860	N-Acetylmuramoyl-L-alanine amidase
EYR00_RS12785	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYR00_RS12785	COG3711	transcriptional antiterminator
EYR00_RS12790	COG2723	6-phospho-beta-galactosidase activity
EYR00_RS12795	COG1482	cell wall glycoprotein biosynthetic process
EYR00_RS12810	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYR00_RS12870	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EYR00_RS12890	COG1403	HNH endonuclease
EYR00_RS12895	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EYR00_RS12900	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EYR00_RS12920	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EYR00_RS12935	COG0083	homoserine kinase activity
EYR00_RS12940	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EYR00_RS12945	COG0460	homoserine dehydrogenase
EYR00_RS12955	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EYR00_RS12965	COG1733	regulation of RNA biosynthetic process
EYR00_RS12970	COG0785	Cytochrome C biogenesis protein
EYR00_RS12980	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EYR00_RS12990	COG0640	Transcriptional regulator
EYR00_RS13010	COG1307	EDD domain protein, DegV family
EYR00_RS13025	COG0745	RESPONSE REGULATOR receiver
EYR00_RS13030	COG0704	Plays a role in the regulation of phosphate uptake
EYR00_RS13035	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EYR00_RS13040	COG0581	inorganic phosphate transmembrane transporter activity
EYR00_RS13045	COG0573	inorganic phosphate transmembrane transporter activity
EYR00_RS13050	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EYR00_RS13065	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EYR00_RS13085	COG0436	Aminotransferase
EYR00_RS13100	COG2706	6-phosphogluconolactonase activity
EYR00_RS13120	COG2169	Transcriptional regulator
EYR00_RS13125	COG4708	membrane
EYR00_RS13135	COG2203	Gaf domain
EYR00_RS13135	COG2199	diguanylate cyclase activity
EYR00_RS13150	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EYR00_RS13160	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EYR00_RS13180	COG0366	Alpha amylase catalytic
EYR00_RS13185	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EYR00_RS13195	COG0561	phosphatase activity
EYR00_RS13200	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EYR00_RS13205	COG0367	asparagine synthase
EYR00_RS13215	COG1671	Belongs to the UPF0178 family
EYR00_RS13230	COG3300	MHYT domain
EYR00_RS13230	COG5001	Diguanylate cyclase
EYR00_RS13255	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EYR00_RS13280	COG0504	CTP synthase activity
EYR00_RS13290	COG1454	alcohol dehydrogenase
EYR00_RS13290	COG1012	belongs to the aldehyde dehydrogenase family
EYR00_RS13295	COG0584	glycerophosphoryl diester phosphodiesterase
EYR00_RS13305	COG0561	phosphatase activity
EYR00_RS13310	COG2032	superoxide dismutase activity
EYR00_RS13325	COG0250	Participates in transcription elongation, termination and antitermination
EYR00_RS13335	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EYR00_RS13345	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EYR00_RS13350	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EYR00_RS13355	COG0215	cysteine-tRNA ligase activity
EYR00_RS13365	COG0561	phosphatase activity
EYR00_RS13385	COG3773	Cell wall hydrolase
EYR00_RS13395	COG0367	asparagine synthase
EYR00_RS13405	COG0285	dihydrofolate synthase activity
EYR00_RS13410	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EYR00_RS13415	COG0561	phosphatase activity
EYR00_RS13420	COG0561	phosphatase activity
EYR00_RS13445	COG0456	acetyltransferase
EYR00_RS13445	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EYR00_RS13450	COG0534	Mate efflux family protein
EYR00_RS13455	COG1362	aminopeptidase activity
EYR00_RS13470	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EYR00_RS13470	COG3064	Membrane
EYR00_RS13470	COG3583	domain protein
EYR00_RS13475	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EYR00_RS13495	COG3620	sequence-specific DNA binding
EYR00_RS13515	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EYR00_RS13515	COG0493	'glutamate synthase
EYR00_RS13530	COG3279	Response regulator of the LytR AlgR family
EYR00_RS13545	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EYR00_RS13570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYR00_RS13575	COG0157	Belongs to the NadC ModD family
EYR00_RS13585	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EYR00_RS13590	COG0288	reversible hydration of carbon dioxide
EYR00_RS13595	COG0443	Heat shock 70 kDa protein
EYR00_RS13600	COG0484	heat shock protein binding
EYR00_RS13615	COG3290	protein histidine kinase activity
EYR00_RS13630	COG2723	6-phospho-beta-galactosidase activity
EYR00_RS13635	COG0534	Mate efflux family protein
EYR00_RS13650	COG0583	DNA-binding transcription factor activity
EYR00_RS13655	COG2205	protein histidine kinase activity
EYR00_RS13655	COG2770	Histidine kinase
EYR00_RS13660	COG0745	RESPONSE REGULATOR receiver
EYR00_RS13665	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EYR00_RS13685	COG1528	Iron-storage protein
EYR00_RS13690	COG0493	'glutamate synthase
EYR00_RS13695	COG0070	glutamate synthase
EYR00_RS13695	COG0069	glutamate synthase activity
EYR00_RS13695	COG0067	glutamate synthase
EYR00_RS13700	COG4869	propanediol catabolic process
EYR00_RS13720	COG1285	pathogenesis
EYR00_RS13735	COG1737	Transcriptional regulator
EYR00_RS13740	COG2723	6-phospho-beta-galactosidase activity
EYR00_RS13745	COG2199	diguanylate cyclase activity
EYR00_RS13745	COG2203	Gaf domain
EYR00_RS13750	COG1073	alpha beta
EYR00_RS13765	COG0101	tRNA pseudouridine synthase activity
EYR00_RS13770	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EYR00_RS13775	COG1122	ATPase activity
EYR00_RS13790	COG0202	RNA polymerase activity
EYR00_RS13795	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EYR00_RS13800	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EYR00_RS13810	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EYR00_RS13815	COG0024	Methionine aminopeptidase
EYR00_RS13820	COG0563	adenylate kinase activity
EYR00_RS13825	COG0201	protein transport
EYR00_RS13835	COG1841	ribosomal large subunit assembly
EYR00_RS13840	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EYR00_RS13845	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EYR00_RS13850	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EYR00_RS13855	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EYR00_RS13860	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EYR00_RS13865	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EYR00_RS13875	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EYR00_RS13880	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EYR00_RS13895	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EYR00_RS13900	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EYR00_RS13905	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EYR00_RS13910	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EYR00_RS13915	COG0089	rRNA binding
EYR00_RS13925	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EYR00_RS13930	COG0051	transcription antitermination factor activity, RNA binding
EYR00_RS13935	COG0406	alpha-ribazole phosphatase activity
EYR00_RS14010	COG1447	Phosphotransferase system cellobiose-specific component IIA
EYR00_RS14020	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EYR00_RS14025	COG0049	tRNA binding
EYR00_RS14030	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EYR00_RS14050	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EYR00_RS14055	COG0085	RNA polymerase activity
EYR00_RS14060	COG2813	Specifically methylates the guanine in position
EYR00_RS14065	COG0222	ribosome binding
EYR00_RS14070	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EYR00_RS14075	COG0081	regulation of translation
EYR00_RS14080	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EYR00_RS14085	COG1028	Short-chain dehydrogenase reductase Sdr
EYR00_RS14090	COG2033	superoxide reductase activity
EYR00_RS14100	COG0126	phosphoglycerate kinase activity
EYR00_RS14115	COG1174	glycine betaine transport
EYR00_RS14165	COG4716	Myosin-crossreactive antigen
EYR00_RS14180	COG0028	Belongs to the TPP enzyme family
EYR00_RS14190	COG0473	3-isopropylmalate dehydrogenase activity
EYR00_RS14195	COG0066	3-isopropylmalate dehydratase activity
EYR00_RS14200	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EYR00_RS14215	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EYR00_RS14235	COG1131	(ABC) transporter
EYR00_RS14250	COG1181	Belongs to the D-alanine--D-alanine ligase family
EYR00_RS14255	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EYR00_RS14270	COG0673	inositol 2-dehydrogenase activity
EYR00_RS14285	COG0024	Methionine aminopeptidase
EYR00_RS14290	COG1408	metallophosphoesterase
EYR00_RS14300	COG0673	inositol 2-dehydrogenase activity
EYR00_RS14305	COG0673	inositol 2-dehydrogenase activity
EYR00_RS14310	COG2723	6-phospho-beta-galactosidase activity
EYR00_RS14320	COG1737	Transcriptional regulator
EYR00_RS14335	COG2723	6-phospho-beta-galactosidase activity
EYR00_RS14340	COG1482	cell wall glycoprotein biosynthetic process
EYR00_RS14355	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYR00_RS14360	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYR00_RS14360	COG3711	transcriptional antiterminator
EYR00_RS14365	COG0698	ribose 5-phosphate isomerase
EYR00_RS14370	COG2723	6-phospho-beta-galactosidase activity
EYR00_RS14380	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EYR00_RS14390	COG2723	6-phospho-beta-galactosidase activity
EYR00_RS14395	COG2723	6-phospho-beta-galactosidase activity
EYR00_RS14400	COG1312	Catalyzes the dehydration of D-mannonate
EYR00_RS14405	COG1414	Transcriptional regulator
EYR00_RS14415	COG1414	Transcriptional regulator
EYR00_RS14420	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYR00_RS14450	COG1316	TRANSCRIPTIONal
EYR00_RS14455	COG4509	Sortase family
EYR00_RS14460	COG0012	GTP binding
EYR00_RS14485	COG1966	Carbon starvation protein
EYR00_RS14505	COG1447	Phosphotransferase system cellobiose-specific component IIA
EYR00_RS14510	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EYR00_RS14510	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EYR00_RS14515	COG1132	(ABC) transporter
EYR00_RS14520	COG1132	(ABC) transporter
EYR00_RS14525	COG0789	Transcriptional regulator
EYR00_RS14565	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EYR00_RS14580	COG1136	(ABC) transporter
EYR00_RS14585	COG2205	protein histidine kinase activity
EYR00_RS14590	COG0745	RESPONSE REGULATOR receiver
EYR00_RS14595	COG0584	glycerophosphoryl diester phosphodiesterase
EYR00_RS14605	COG4978	Transcriptional regulator
EYR00_RS14605	COG0789	Transcriptional regulator
EYR00_RS14610	COG1733	regulation of RNA biosynthetic process
EYR00_RS14620	COG2723	6-phospho-beta-galactosidase activity
EYR00_RS14625	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
EYR00_RS14635	COG1342	Belongs to the UPF0251 family
EYR00_RS14640	COG1263	PTS System
EYR00_RS14640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYR00_RS14640	COG2190	(PTS) system
EYR00_RS14645	COG2723	6-phospho-beta-galactosidase activity
EYR00_RS14650	COG1447	Phosphotransferase system cellobiose-specific component IIA
EYR00_RS14655	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYR00_RS14665	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYR00_RS14670	COG1486	melibiose metabolic process
EYR00_RS14675	COG1737	Transcriptional regulator
EYR00_RS14720	COG3620	sequence-specific DNA binding
EYR00_RS14730	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYR00_RS14770	COG0366	Alpha amylase catalytic
EYR00_RS14780	COG1733	regulation of RNA biosynthetic process
EYR00_RS14800	COG0205	6-phosphofructokinase activity
EYR00_RS14810	COG0363	glucosamine-6-phosphate deaminase activity
EYR00_RS14815	COG5001	Diguanylate cyclase
EYR00_RS14830	COG1151	hydroxylamine reductase activity
EYR00_RS14840	COG2315	Protein conserved in bacteria
EYR00_RS14850	COG0667	Aldo Keto reductase
EYR00_RS14865	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EYR00_RS14880	COG0640	Transcriptional regulator
EYR00_RS14915	COG0492	ferredoxin-NADP+ reductase activity
EYR00_RS14920	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EYR00_RS14930	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EYR00_RS14935	COG0351	phosphomethylpyrimidine kinase
EYR00_RS14940	COG5001	Diguanylate cyclase
EYR00_RS14940	COG3300	MHYT domain
EYR00_RS14945	COG1115	amino acid carrier protein
EYR00_RS14955	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
EYR00_RS14990	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EYR00_RS14995	COG0205	6-phosphofructokinase activity
EYR00_RS15000	COG2723	6-phospho-beta-galactosidase activity
EYR00_RS15005	COG3958	Transketolase
EYR00_RS15010	COG3959	Transketolase, thiamine diphosphate binding domain
EYR00_RS15020	COG1349	DNA-binding transcription factor activity
EYR00_RS15025	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EYR00_RS15030	COG0629	single-stranded DNA binding
EYR00_RS15045	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EYR00_RS15055	COG0586	Pfam SNARE associated Golgi protein
EYR00_RS15060	COG0542	response to heat
EYR00_RS15065	COG5001	Diguanylate cyclase
EYR00_RS15065	COG3300	MHYT domain
EYR00_RS15075	COG2357	RelA SpoT domain protein
EYR00_RS15090	COG0583	DNA-binding transcription factor activity
EYR00_RS15110	COG0019	diaminopimelate decarboxylase activity
EYR00_RS15115	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EYR00_RS15120	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EYR00_RS15135	COG0110	maltose O-acetyltransferase activity
EYR00_RS15140	COG0577	efflux transmembrane transporter activity
EYR00_RS15145	COG1136	(ABC) transporter
EYR00_RS15150	COG5002	protein histidine kinase activity
EYR00_RS15155	COG0745	RESPONSE REGULATOR receiver
EYR00_RS15175	COG2239	Acts as a magnesium transporter
EYR00_RS15185	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYR00_RS15190	COG1737	Transcriptional regulator
EYR00_RS15195	COG5001	Diguanylate cyclase
EYR00_RS15210	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EYR00_RS15215	COG3142	Participates in the control of copper homeostasis
EYR00_RS15220	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EYR00_RS15225	COG1446	asparaginase
EYR00_RS15235	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYR00_RS15240	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYR00_RS15245	COG1447	Phosphotransferase system cellobiose-specific component IIA
EYR00_RS15255	COG3711	transcriptional antiterminator
EYR00_RS15255	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYR00_RS15260	COG1393	Belongs to the ArsC family
EYR00_RS15275	COG2270	Major facilitator Superfamily
EYR00_RS15295	COG0745	RESPONSE REGULATOR receiver
EYR00_RS15300	COG2205	protein histidine kinase activity
EYR00_RS15305	COG0745	RESPONSE REGULATOR receiver
EYR00_RS15310	COG2205	protein histidine kinase activity
EYR00_RS15335	COG0765	amino acid transport
EYR00_RS15370	COG1253	flavin adenine dinucleotide binding
EYR00_RS15375	COG0534	Mate efflux family protein
EYR00_RS15385	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYR00_RS15400	COG0668	transmembrane transport
EYR00_RS15415	COG0673	inositol 2-dehydrogenase activity
EYR00_RS15430	COG3279	Response regulator of the LytR AlgR family
EYR00_RS15435	COG2190	(PTS) system
EYR00_RS15440	COG1737	Transcriptional regulator
EYR00_RS15450	COG1263	PTS System
EYR00_RS15450	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYR00_RS15455	COG1486	melibiose metabolic process
EYR00_RS15465	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EYR00_RS15475	COG0789	Transcriptional regulator
EYR00_RS15500	COG0594	ribonuclease P activity
EYR00_RS15505	COG0230	Belongs to the bacterial ribosomal protein bL34 family