locus-tag	class	description
AB984_RS00010	COG0592	DNA-directed DNA polymerase activity
AB984_RS00015	COG1349	DNA-binding transcription factor activity
AB984_RS00020	COG1105	Belongs to the carbohydrate kinase PfkB family
AB984_RS00025	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AB984_RS00025	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AB984_RS00025	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AB984_RS00030	COG2501	S4 domain
AB984_RS00035	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AB984_RS00040	COG0187	DNA topoisomerase II activity
AB984_RS00045	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AB984_RS00050	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AB984_RS00055	COG0561	phosphatase activity
AB984_RS00075	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AB984_RS00100	COG0772	Belongs to the SEDS family
AB984_RS00110	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AB984_RS00115	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AB984_RS00125	COG3842	ATPase activity
AB984_RS00135	COG1136	(ABC) transporter
AB984_RS00140	COG1307	EDD domain protein, DegV family
AB984_RS00145	COG1307	EDD domain protein, DegV family
AB984_RS00150	COG1739	Uncharacterized protein family UPF0029
AB984_RS00160	COG2514	catechol 2,3-dioxygenase activity
AB984_RS00165	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AB984_RS00185	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AB984_RS00190	COG0284	orotidine-5'-phosphate decarboxylase activity
AB984_RS00210	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AB984_RS00220	COG0803	Belongs to the bacterial solute-binding protein 9 family
AB984_RS00225	COG1121	(ABC) transporter
AB984_RS00230	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AB984_RS00235	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AB984_RS00250	COG0546	phosphoglycolate phosphatase activity
AB984_RS00275	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AB984_RS00280	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AB984_RS00290	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AB984_RS00300	COG4946	Tricorn protease homolog
AB984_RS00300	COG0823	Involved in the tonB-independent uptake of proteins
AB984_RS00300	COG1506	peptidase
AB984_RS00310	COG2357	RelA SpoT domain protein
AB984_RS00315	COG4841	protein insertion into membrane
AB984_RS00325	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AB984_RS00365	COG3621	Patatin-like phospholipase
AB984_RS00370	COG0656	L-ascorbic acid biosynthetic process
AB984_RS00375	COG2217	Heavy metal translocating P-type atpase
AB984_RS00410	COG2252	PERMEase
AB984_RS00425	COG0346	lactoylglutathione lyase activity
AB984_RS00430	COG1846	Transcriptional regulator
AB984_RS00440	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AB984_RS00455	COG1217	gtp-binding protein TYPA
AB984_RS00460	COG0343	queuine tRNA-ribosyltransferase activity
AB984_RS00465	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AB984_RS00480	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AB984_RS00485	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AB984_RS00485	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AB984_RS00500	COG1132	(ABC) transporter
AB984_RS00505	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AB984_RS00545	COG1328	CTP reductase activity
AB984_RS00545	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AB984_RS00550	COG3655	Transcriptional regulator
AB984_RS00555	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AB984_RS00560	COG0557	exoribonuclease II activity
AB984_RS00565	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AB984_RS00570	COG1704	LemA family
AB984_RS00580	COG1132	(ABC) transporter
AB984_RS00585	COG1132	(ABC) transporter
AB984_RS00590	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AB984_RS00600	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AB984_RS00605	COG0745	RESPONSE REGULATOR receiver
AB984_RS00610	COG2205	protein histidine kinase activity
AB984_RS00610	COG2770	Histidine kinase
AB984_RS00630	COG4684	Psort location CytoplasmicMembrane, score
AB984_RS00635	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AB984_RS00640	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AB984_RS00650	COG1309	transcriptional regulator
AB984_RS00685	COG3775	system Galactitol-specific IIC component
AB984_RS00695	COG3414	Phosphotransferase system galactitol-specific IIB component
AB984_RS00700	COG3711	transcriptional antiterminator
AB984_RS00700	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AB984_RS00725	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AB984_RS00730	COG0222	ribosome binding
AB984_RS00740	COG0085	RNA polymerase activity
AB984_RS00745	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AB984_RS00750	COG0483	inositol monophosphate 1-phosphatase activity
AB984_RS00755	COG0483	inositol monophosphate 1-phosphatase activity
AB984_RS00760	COG2267	carboxylic ester hydrolase activity
AB984_RS00765	COG2207	Transcriptional regulator
AB984_RS00770	COG5492	domain, Protein
AB984_RS00775	COG1876	peptidase activity
AB984_RS00785	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AB984_RS00795	COG0534	Mate efflux family protein
AB984_RS00805	COG0438	transferase activity, transferring glycosyl groups
AB984_RS00830	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AB984_RS00835	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AB984_RS00840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AB984_RS00865	COG0584	glycerophosphoryl diester phosphodiesterase
AB984_RS00870	COG3682	Transcriptional regulator
AB984_RS00890	COG1309	transcriptional regulator
AB984_RS00895	COG0450	alkyl hydroperoxide reductase
AB984_RS00905	COG2226	methyltransferase
AB984_RS00920	COG0495	leucyl-tRNA aminoacylation
AB984_RS00960	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AB984_RS00980	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AB984_RS00985	COG1346	cytolysis
AB984_RS00990	COG1380	Effector of murein hydrolase LrgA
AB984_RS01010	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AB984_RS01045	COG0280	phosphate acetyltransferase
AB984_RS01055	COG3842	ATPase activity
AB984_RS01075	COG4152	abc transporter atp-binding protein
AB984_RS01120	COG0745	RESPONSE REGULATOR receiver
AB984_RS01125	COG0642	Histidine kinase
AB984_RS01125	COG5002	protein histidine kinase activity
AB984_RS01140	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
AB984_RS01160	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AB984_RS01175	COG2190	(PTS) system
AB984_RS01175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AB984_RS01175	COG1263	PTS System
AB984_RS01185	COG3583	domain protein
AB984_RS01185	COG3064	Membrane
AB984_RS01185	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AB984_RS01190	COG1175	transmembrane transport
AB984_RS01195	COG0395	ABC-type sugar transport system, permease component
AB984_RS01200	COG1653	transport
AB984_RS01210	COG2972	Histidine kinase
AB984_RS01215	COG4753	response regulator
AB984_RS01215	COG2207	Transcriptional regulator
AB984_RS01230	COG1609	Transcriptional regulator
AB984_RS01240	COG0383	alpha-mannosidase activity
AB984_RS01245	COG2723	6-phospho-beta-galactosidase activity
AB984_RS01250	COG1940	carbohydrate kinase activity
AB984_RS01260	COG1482	cell wall glycoprotein biosynthetic process
AB984_RS01290	COG2801	Transposase and inactivated derivatives
AB984_RS01320	COG0024	Methionine aminopeptidase
AB984_RS01325	COG3711	transcriptional antiterminator
AB984_RS01330	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
AB984_RS01335	COG2190	(PTS) system
AB984_RS01335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AB984_RS01335	COG1263	PTS System
AB984_RS01355	COG1278	Cold shock
AB984_RS01375	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AB984_RS01395	COG2197	response regulator
AB984_RS01425	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
AB984_RS01450	COG3716	PTS system mannose fructose sorbose family IID component
AB984_RS01455	COG3715	PTS system
AB984_RS01460	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AB984_RS01465	COG2207	Transcriptional regulator
AB984_RS01475	COG2222	sugar isomerase
AB984_RS01510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AB984_RS01515	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AB984_RS01520	COG1116	anion transmembrane transporter activity
AB984_RS01525	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AB984_RS01530	COG0513	Belongs to the DEAD box helicase family
AB984_RS01540	COG1242	4 iron, 4 sulfur cluster binding
AB984_RS01550	COG1187	pseudouridine synthase activity
AB984_RS01560	COG0446	pyridine nucleotide-disulphide oxidoreductase
AB984_RS01570	COG0728	peptidoglycan biosynthetic process
AB984_RS01590	COG5002	protein histidine kinase activity
AB984_RS01600	COG0745	RESPONSE REGULATOR receiver
AB984_RS01605	COG0642	Histidine kinase
AB984_RS01605	COG5002	protein histidine kinase activity
AB984_RS01615	COG0583	DNA-binding transcription factor activity
AB984_RS01640	COG2188	Transcriptional regulator
AB984_RS01650	COG1129	ABC transporter
AB984_RS01655	COG1131	(ABC) transporter
AB984_RS01665	COG0564	pseudouridine synthase activity
AB984_RS01695	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AB984_RS01705	COG0564	pseudouridine synthase activity
AB984_RS01710	COG0116	Belongs to the methyltransferase superfamily
AB984_RS01710	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AB984_RS01720	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AB984_RS01730	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AB984_RS01735	COG0154	amidase activity
AB984_RS01785	COG1164	Oligoendopeptidase f
AB984_RS01800	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AB984_RS01800	COG3711	transcriptional antiterminator
AB984_RS01805	COG3716	PTS system mannose fructose sorbose family IID component
AB984_RS01810	COG3715	PTS system
AB984_RS01825	COG1780	Probably involved in ribonucleotide reductase function
AB984_RS01830	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AB984_RS01835	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AB984_RS01850	COG0668	transmembrane transport
AB984_RS01855	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AB984_RS01860	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AB984_RS01875	COG2183	response to ionizing radiation
AB984_RS01890	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AB984_RS01900	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AB984_RS01905	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AB984_RS01915	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AB984_RS01925	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AB984_RS01930	COG0569	domain protein
AB984_RS01935	COG3118	belongs to the thioredoxin family
AB984_RS01940	COG0425	Belongs to the sulfur carrier protein TusA family
AB984_RS01940	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AB984_RS01945	COG1937	Protein conserved in bacteria
AB984_RS01970	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AB984_RS01985	COG1196	nuclear chromosome segregation
AB984_RS01995	COG0110	maltose O-acetyltransferase activity
AB984_RS02040	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AB984_RS02045	COG0047	phosphoribosylformylglycinamidine synthase activity
AB984_RS02055	COG2706	6-phosphogluconolactonase activity
AB984_RS02060	COG1486	melibiose metabolic process
AB984_RS02065	COG0561	phosphatase activity
AB984_RS02070	COG1737	Transcriptional regulator
AB984_RS02080	COG1696	Membrane protein involved in D-alanine export
AB984_RS02090	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AB984_RS02095	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AB984_RS02100	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AB984_RS02105	COG5263	repeat protein
AB984_RS02105	COG4193	domain, Protein
AB984_RS02125	COG4120	Belongs to the binding-protein-dependent transport system permease family
AB984_RS02130	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AB984_RS02150	COG3842	ATPase activity
AB984_RS02160	COG0395	ABC-type sugar transport system, permease component
AB984_RS02170	COG1653	transport
AB984_RS02185	COG1428	Deoxynucleoside kinase
AB984_RS02190	COG1045	serine acetyltransferase
AB984_RS02200	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AB984_RS02215	COG1132	(ABC) transporter
AB984_RS02220	COG1132	(ABC) transporter
AB984_RS02225	COG1363	Peptidase, m42
AB984_RS02240	COG2188	Transcriptional regulator
AB984_RS02245	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AB984_RS02250	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AB984_RS02255	COG0006	proline dipeptidase activity
AB984_RS02275	COG0095	Lipoate-protein ligase
AB984_RS02305	COG0601	transmembrane transport
AB984_RS02310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AB984_RS02315	COG4608	Belongs to the ABC transporter superfamily
AB984_RS02320	COG0444	Belongs to the ABC transporter superfamily
AB984_RS02335	COG1132	(ABC) transporter
AB984_RS02340	COG1132	(ABC) transporter
AB984_RS02350	COG0546	phosphoglycolate phosphatase activity
AB984_RS02365	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AB984_RS02370	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AB984_RS02375	COG0588	phosphoglycerate mutase activity
AB984_RS02385	COG0596	Alpha beta hydrolase
AB984_RS02400	COG3579	cysteine-type endopeptidase activity
AB984_RS02425	COG1253	flavin adenine dinucleotide binding
AB984_RS02450	COG4472	Bacterial protein of unknown function (DUF965)
AB984_RS02455	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AB984_RS02465	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AB984_RS02470	COG0572	uridine kinase
AB984_RS02485	COG0658	competence protein
AB984_RS02485	COG2333	competence protein COMEC
AB984_RS02495	COG0268	Binds directly to 16S ribosomal RNA
AB984_RS02500	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AB984_RS02510	COG0481	GTPase activity
AB984_RS02520	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AB984_RS02530	COG2084	Dehydrogenase
AB984_RS02540	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AB984_RS02545	COG1185	polyribonucleotide nucleotidyltransferase activity
AB984_RS02555	COG0537	adenosine 5'-monophosphoramidase activity
AB984_RS02560	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AB984_RS02565	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AB984_RS02575	COG0719	Fe-S assembly protein
AB984_RS02580	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AB984_RS02585	COG0822	iron-sulfur transferase activity
AB984_RS02595	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AB984_RS02610	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AB984_RS02620	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AB984_RS02630	COG1104	cysteine desulfurase activity
AB984_RS02635	COG0301	tRNA thio-modification
AB984_RS02640	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AB984_RS02645	COG0335	large ribosomal subunit rRNA binding
AB984_RS02650	COG0681	Belongs to the peptidase S26 family
AB984_RS02655	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AB984_RS02660	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AB984_RS02665	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AB984_RS02665	COG0758	DNA mediated transformation
AB984_RS02670	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AB984_RS02675	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AB984_RS02680	COG4974	Belongs to the 'phage' integrase family
AB984_RS02695	COG1316	TRANSCRIPTIONal
AB984_RS02705	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AB984_RS02710	COG0728	peptidoglycan biosynthetic process
AB984_RS02720	COG0275	rRNA processing
AB984_RS02730	COG0768	penicillin binding
AB984_RS02735	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AB984_RS02740	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AB984_RS02755	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AB984_RS02755	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AB984_RS02765	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AB984_RS02770	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AB984_RS02775	COG0124	histidyl-tRNA synthetase
AB984_RS02780	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AB984_RS02785	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AB984_RS02790	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AB984_RS02795	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AB984_RS02810	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AB984_RS02820	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AB984_RS02835	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AB984_RS02840	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AB984_RS02845	COG1323	Belongs to the UPF0348 family
AB984_RS02850	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AB984_RS02855	COG1363	Peptidase, m42
AB984_RS02870	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AB984_RS02900	COG2264	protein methyltransferase activity
AB984_RS02910	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AB984_RS02930	COG1420	regulation of RNA biosynthetic process
AB984_RS02935	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AB984_RS03230	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AB984_RS03235	COG0438	transferase activity, transferring glycosyl groups
AB984_RS03240	COG3481	metal-dependent phosphohydrolase, HD sub domain
AB984_RS03245	COG0228	four-way junction DNA binding
AB984_RS03255	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AB984_RS03260	COG0336	Belongs to the RNA methyltransferase TrmD family
AB984_RS03270	COG1686	Belongs to the peptidase S11 family
AB984_RS03280	COG0436	Aminotransferase
AB984_RS03285	COG0052	Belongs to the universal ribosomal protein uS2 family
AB984_RS03290	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AB984_RS03295	COG0528	UMP kinase activity
AB984_RS03300	COG0233	cytoplasmic translational termination
AB984_RS03310	COG0575	Belongs to the CDS family
AB984_RS03325	COG1272	protein, Hemolysin III
AB984_RS03330	COG4193	domain, Protein
AB984_RS03330	COG5263	repeat protein
AB984_RS03350	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AB984_RS03355	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AB984_RS03360	COG1181	Belongs to the D-alanine--D-alanine ligase family
AB984_RS03365	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AB984_RS03370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AB984_RS03375	COG3331	DNA recombination
AB984_RS03380	COG3599	regulation of cell shape
AB984_RS03395	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AB984_RS03410	COG1692	metallophosphoesterase
AB984_RS03415	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AB984_RS03420	COG1280	lysine exporter protein (LysE YggA)
AB984_RS03420	COG1674	ftsk spoiiie
AB984_RS03445	COG3763	UPF0154 protein
AB984_RS03455	COG0180	Tryptophanyl-tRNA synthetase
AB984_RS03460	COG1393	Belongs to the ArsC family
AB984_RS03475	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AB984_RS03480	COG1970	mechanosensitive ion channel activity
AB984_RS03485	COG2195	Cleaves the N-terminal amino acid of tripeptides
AB984_RS03535	COG1131	(ABC) transporter
AB984_RS03540	COG1136	(ABC) transporter
AB984_RS03590	COG5290	Psort location Cytoplasmic, score
AB984_RS03625	COG1131	(ABC) transporter
AB984_RS03645	COG1131	(ABC) transporter
AB984_RS03650	COG0656	L-ascorbic acid biosynthetic process
AB984_RS03655	COG4895	conserved protein (DUF2196)
AB984_RS03680	COG1349	DNA-binding transcription factor activity
AB984_RS03690	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AB984_RS03695	COG3037	sugar-specific permease SgaT UlaA
AB984_RS03710	COG3623	hexulose-6-phosphate isomerase
AB984_RS03715	COG0235	Class ii aldolase
AB984_RS03725	COG0281	malic enzyme
AB984_RS03730	COG0114	fumarate hydratase activity
AB984_RS03735	COG1027	Aspartate ammonia-lyase
AB984_RS03745	COG0577	efflux transmembrane transporter activity
AB984_RS03745	COG1136	(ABC) transporter
AB984_RS03750	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AB984_RS03760	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AB984_RS03760	COG3064	Membrane
AB984_RS03760	COG3583	domain protein
AB984_RS03770	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AB984_RS03775	COG0514	ATP-dependent DNA helicase (RecQ)
AB984_RS03785	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AB984_RS03810	COG1268	BioY protein
AB984_RS03815	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AB984_RS03815	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AB984_RS03820	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
AB984_RS03820	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
AB984_RS03850	COG5016	pyruvate
AB984_RS03850	COG0511	ligase activity, forming carbon-carbon bonds
AB984_RS03860	COG0511	ligase activity, forming carbon-carbon bonds
AB984_RS03865	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
AB984_RS03895	COG5492	domain, Protein
AB984_RS03900	COG1114	Component of the transport system for branched-chain amino acids
AB984_RS03925	COG3475	LICD family
AB984_RS03935	COG0561	phosphatase activity
AB984_RS03965	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AB984_RS03970	COG3250	beta-galactosidase activity
AB984_RS03990	COG0523	cobalamin synthesis protein
AB984_RS04015	COG0564	pseudouridine synthase activity
AB984_RS04020	COG2832	Protein of unknown function (DUF454)
AB984_RS04025	COG4988	ABC transporter
AB984_RS04030	COG1132	(ABC) transporter
AB984_RS04035	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AB984_RS04040	COG2235	arginine
AB984_RS04045	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AB984_RS04050	COG0549	Belongs to the carbamate kinase family
AB984_RS04055	COG1288	antiporter activity
AB984_RS04080	COG1597	lipid kinase activity
AB984_RS04095	COG3279	Response regulator of the LytR AlgR family
AB984_RS04100	COG1131	(ABC) transporter
AB984_RS04135	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AB984_RS04155	COG2188	Transcriptional regulator
AB984_RS04160	COG0488	(ABC) transporter
AB984_RS04210	COG0489	protein tyrosine kinase activity
AB984_RS04255	COG2409	Drug exporters of the RND superfamily
AB984_RS04270	COG1114	Component of the transport system for branched-chain amino acids
AB984_RS04280	COG1546	Belongs to the CinA family
AB984_RS04280	COG1058	Belongs to the CinA family
AB984_RS04285	COG0288	reversible hydration of carbon dioxide
AB984_RS04290	COG0488	(ABC) transporter
AB984_RS04305	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AB984_RS04315	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AB984_RS04330	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AB984_RS04335	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AB984_RS04350	COG1086	Polysaccharide biosynthesis protein
AB984_RS04370	COG4750	Nucleotidyl transferase
AB984_RS04375	COG3475	LICD family
AB984_RS04380	COG0697	spore germination
AB984_RS04385	COG4750	Nucleotidyl transferase
AB984_RS04400	COG2848	UPF0210 protein
AB984_RS04415	COG0745	RESPONSE REGULATOR receiver
AB984_RS04420	COG5002	protein histidine kinase activity
AB984_RS04425	COG0577	efflux transmembrane transporter activity
AB984_RS04430	COG1136	(ABC) transporter
AB984_RS04435	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AB984_RS04445	COG3842	ATPase activity
AB984_RS04455	COG1176	ABC-type spermidine putrescine transport system, permease component I
AB984_RS04480	COG0497	DNA recombination
AB984_RS04485	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AB984_RS04495	COG1722	exodeoxyribonuclease VII activity
AB984_RS04500	COG1570	exodeoxyribonuclease VII activity
AB984_RS04505	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AB984_RS04525	COG0196	riboflavin kinase activity
AB984_RS04535	COG0765	amino acid transport
AB984_RS04540	COG1126	abc transporter atp-binding protein
AB984_RS04545	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AB984_RS04550	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AB984_RS04555	COG1358	cellular component organization or biogenesis
AB984_RS04560	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AB984_RS04565	COG0195	Participates in both transcription termination and antitermination
AB984_RS04575	COG2176	DNA-directed DNA polymerase activity
AB984_RS04580	COG0571	ribonuclease III activity
AB984_RS04585	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AB984_RS04590	COG1461	Dihydroxyacetone kinase
AB984_RS04595	COG1302	Protein conserved in bacteria
AB984_RS04600	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AB984_RS04615	COG0632	four-way junction helicase activity
AB984_RS04620	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AB984_RS04625	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AB984_RS04630	COG2868	ribosomal protein
AB984_RS04635	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AB984_RS04640	COG0726	polysaccharide deacetylase
AB984_RS04650	COG5002	protein histidine kinase activity
AB984_RS04655	COG0745	RESPONSE REGULATOR receiver
AB984_RS04660	COG0587	DNA-directed DNA polymerase activity
AB984_RS04665	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AB984_RS04670	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AB984_RS04675	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
AB984_RS04680	COG0552	protein localization to endoplasmic reticulum
AB984_RS04695	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AB984_RS04700	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AB984_RS04705	COG0799	negative regulation of ribosome biogenesis
AB984_RS04710	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AB984_RS04720	COG1160	GTP binding
AB984_RS04725	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AB984_RS04730	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AB984_RS04735	COG0187	DNA topoisomerase II activity
AB984_RS04740	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AB984_RS04745	COG4555	ABC transporter
AB984_RS04760	COG0217	transcriptional regulatory protein
AB984_RS04765	COG0072	phenylalanine-tRNA ligase activity
AB984_RS04765	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AB984_RS04770	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AB984_RS04775	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AB984_RS04780	COG1121	(ABC) transporter
AB984_RS04785	COG0446	pyridine nucleotide-disulphide oxidoreductase
AB984_RS04795	COG2738	Putative neutral zinc metallopeptidase
AB984_RS04800	COG0776	regulation of translation
AB984_RS04805	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AB984_RS04810	COG1160	GTP binding
AB984_RS04830	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AB984_RS04845	COG4537	Required for transformation and DNA binding
AB984_RS04855	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AB984_RS04860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AB984_RS04865	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AB984_RS04870	COG0768	penicillin binding
AB984_RS04875	COG0513	Belongs to the DEAD box helicase family
AB984_RS04885	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AB984_RS04890	COG0358	DNA primase activity
AB984_RS04900	COG1381	Involved in DNA repair and RecF pathway recombination
AB984_RS04905	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AB984_RS04910	COG0295	cytidine deaminase activity
AB984_RS04925	COG0704	Plays a role in the regulation of phosphate uptake
AB984_RS04930	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AB984_RS04935	COG0581	inorganic phosphate transmembrane transporter activity
AB984_RS04940	COG0573	inorganic phosphate transmembrane transporter activity
AB984_RS04945	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AB984_RS04950	COG5002	protein histidine kinase activity
AB984_RS04955	COG0745	RESPONSE REGULATOR receiver
AB984_RS04960	COG1702	phosphate starvation-inducible protein PhoH
AB984_RS04965	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AB984_RS04970	COG0513	Belongs to the DEAD box helicase family
AB984_RS04975	COG1132	(ABC) transporter
AB984_RS04980	COG0390	transport system, permease component
AB984_RS04985	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AB984_RS04990	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AB984_RS05005	COG1187	pseudouridine synthase activity
AB984_RS05010	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AB984_RS05015	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AB984_RS05030	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AB984_RS05040	COG0612	Peptidase, M16
AB984_RS05045	COG0612	Peptidase, M16
AB984_RS05050	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AB984_RS05055	COG1079	Belongs to the binding-protein-dependent transport system permease family
AB984_RS05060	COG4603	Belongs to the binding-protein-dependent transport system permease family
AB984_RS05065	COG3845	ABC transporter
AB984_RS05070	COG1744	ABC transporter substrate-binding protein PnrA-like
AB984_RS05075	COG1744	ABC transporter substrate-binding protein PnrA-like
AB984_RS05080	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AB984_RS05090	COG1940	carbohydrate kinase activity
AB984_RS05100	COG0205	6-phosphofructokinase activity
AB984_RS05105	COG1484	DNA-dependent DNA replication
AB984_RS05110	COG3611	Membrane attachment protein
AB984_RS05115	COG0237	dephospho-CoA kinase activity
AB984_RS05125	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AB984_RS05125	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AB984_RS05135	COG0628	permease
AB984_RS05155	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AB984_RS05165	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AB984_RS05175	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AB984_RS05180	COG1162	GTPase activity
AB984_RS05185	COG0515	serine threonine protein kinase
AB984_RS05185	COG2815	serine threonine protein kinase
AB984_RS05195	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AB984_RS05195	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AB984_RS05200	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AB984_RS05205	COG0194	GDP metabolic process
AB984_RS05220	COG0561	phosphatase activity
AB984_RS05240	COG1418	mRNA catabolic process
AB984_RS05245	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AB984_RS05250	COG1394	ATPase activity, coupled to movement of substances
AB984_RS05255	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
AB984_RS05260	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
AB984_RS05280	COG1269	ATP hydrolysis coupled proton transport
AB984_RS05300	COG0205	6-phosphofructokinase activity
AB984_RS05305	COG0488	(ABC) transporter
AB984_RS05315	COG0017	Asparaginyl-tRNA synthetase
AB984_RS05320	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AB984_RS05325	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AB984_RS05335	COG1214	PFAM Peptidase M22, glycoprotease
AB984_RS05340	COG0802	atpase or kinase
AB984_RS05375	COG3557	Belongs to the UPF0374 family
AB984_RS05390	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AB984_RS05395	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AB984_RS05400	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AB984_RS05410	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AB984_RS05415	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AB984_RS05425	COG1799	cell septum assembly
AB984_RS05430	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AB984_RS05440	COG0686	Belongs to the AlaDH PNT family
AB984_RS05450	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AB984_RS05460	COG0254	rRNA binding
AB984_RS05470	COG0419	ATPase involved in DNA repair
AB984_RS05490	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AB984_RS05495	COG4211	Belongs to the binding-protein-dependent transport system permease family
AB984_RS05510	COG1609	Transcriptional regulator
AB984_RS05520	COG0525	valine-tRNA ligase activity
AB984_RS05525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AB984_RS05535	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AB984_RS05545	COG0544	peptidyl-prolyl cis-trans isomerase activity
AB984_RS05575	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AB984_RS05585	COG1193	negative regulation of DNA recombination
AB984_RS05595	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AB984_RS05610	COG0564	pseudouridine synthase activity
AB984_RS05615	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AB984_RS05630	COG0534	Mate efflux family protein
AB984_RS05650	COG1131	(ABC) transporter
AB984_RS05670	COG0488	(ABC) transporter
AB984_RS05675	COG0728	peptidoglycan biosynthetic process
AB984_RS05685	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AB984_RS05700	COG0433	COG0433 Predicted ATPase
AB984_RS05705	COG1447	Phosphotransferase system cellobiose-specific component IIA
AB984_RS05725	COG0488	(ABC) transporter
AB984_RS05770	COG0783	Belongs to the Dps family
AB984_RS05800	COG0101	tRNA pseudouridine synthase activity
AB984_RS05805	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AB984_RS05815	COG1122	ATPase activity
AB984_RS05820	COG2195	Cleaves the N-terminal amino acid of tripeptides
AB984_RS05830	COG0737	Belongs to the 5'-nucleotidase family
AB984_RS05840	COG1476	TRANSCRIPTIONal
AB984_RS05845	COG2971	BadF BadG BcrA BcrD
AB984_RS05855	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AB984_RS05860	COG0203	ribosomal protein L17
AB984_RS05865	COG0202	RNA polymerase activity
AB984_RS05875	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AB984_RS05880	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AB984_RS05885	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AB984_RS05890	COG0024	Methionine aminopeptidase
AB984_RS05895	COG0563	adenylate kinase activity
AB984_RS05900	COG0201	protein transport
AB984_RS05910	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AB984_RS05915	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AB984_RS05925	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AB984_RS05935	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AB984_RS05945	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AB984_RS05950	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AB984_RS05960	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AB984_RS05965	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AB984_RS05970	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AB984_RS05975	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AB984_RS05980	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AB984_RS05985	COG0089	rRNA binding
AB984_RS05990	COG0088	Forms part of the polypeptide exit tunnel
AB984_RS05995	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AB984_RS06000	COG0051	transcription antitermination factor activity, RNA binding
AB984_RS06010	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AB984_RS06015	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AB984_RS06020	COG0049	tRNA binding
AB984_RS06025	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AB984_RS06030	COG0628	permease
AB984_RS06035	COG1525	nuclease
AB984_RS06105	COG1136	(ABC) transporter
AB984_RS06110	COG2205	protein histidine kinase activity
AB984_RS06115	COG0745	RESPONSE REGULATOR receiver
AB984_RS06130	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AB984_RS06140	COG3279	Response regulator of the LytR AlgR family
AB984_RS06165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AB984_RS06170	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AB984_RS06180	COG1164	Oligoendopeptidase f
AB984_RS06190	COG1876	peptidase activity
AB984_RS06195	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AB984_RS06200	COG0363	glucosamine-6-phosphate deaminase activity
AB984_RS06205	COG2824	Alkylphosphonate utilization operon protein PhnA
AB984_RS06210	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AB984_RS06210	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AB984_RS06225	COG1309	transcriptional regulator
AB984_RS06255	COG1609	Transcriptional regulator
AB984_RS06265	COG3716	PTS system mannose fructose sorbose family IID component
AB984_RS06270	COG3715	PTS system
AB984_RS06275	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AB984_RS06280	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AB984_RS06285	COG0800	Aldolase
AB984_RS06295	COG1028	Short-chain dehydrogenase reductase Sdr
AB984_RS06315	COG2081	HI0933 family
AB984_RS06320	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AB984_RS06380	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
AB984_RS06385	COG0395	ABC-type sugar transport system, permease component
AB984_RS06390	COG1175	transmembrane transport
AB984_RS06400	COG1737	Transcriptional regulator
AB984_RS06415	COG1011	Hydrolase
AB984_RS06445	COG0534	Mate efflux family protein
AB984_RS06480	COG1136	(ABC) transporter
AB984_RS06495	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AB984_RS06500	COG0459	protein refolding
AB984_RS06540	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AB984_RS06555	COG2217	Heavy metal translocating P-type atpase
AB984_RS06575	COG2801	Transposase and inactivated derivatives
AB984_RS06590	COG3620	sequence-specific DNA binding
AB984_RS06605	COG1674	ftsk spoiiie
AB984_RS06620	COG0519	Catalyzes the synthesis of GMP from XMP
AB984_RS06620	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AB984_RS06625	COG0517	IMP dehydrogenase activity
AB984_RS06625	COG0516	GMP reductase activity
AB984_RS06650	COG1378	Sugar-specific transcriptional regulator TrmB
AB984_RS06665	COG2217	Heavy metal translocating P-type atpase
AB984_RS06670	COG0640	Transcriptional regulator
AB984_RS06685	COG0492	ferredoxin-NADP+ reductase activity
AB984_RS06695	COG3340	Belongs to the peptidase S51 family
AB984_RS06710	COG1363	Peptidase, m42
AB984_RS06715	COG4977	sequence-specific DNA binding
AB984_RS06720	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AB984_RS06745	COG1760	l-serine dehydratase
AB984_RS06750	COG1760	l-serine dehydratase
AB984_RS06755	COG0251	oxidation-reduction process
AB984_RS06770	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AB984_RS06780	COG4978	Transcriptional regulator
AB984_RS06780	COG0789	Transcriptional regulator
AB984_RS06800	COG2252	PERMEase
AB984_RS06810	COG0149	triose-phosphate isomerase activity
AB984_RS06815	COG0126	phosphoglycerate kinase activity
AB984_RS06825	COG2217	Heavy metal translocating P-type atpase
AB984_RS06830	COG0813	purine-nucleoside phosphorylase activity
AB984_RS06860	COG1012	belongs to the aldehyde dehydrogenase family
AB984_RS06860	COG1454	alcohol dehydrogenase
AB984_RS06880	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AB984_RS06885	COG2011	ABC-type metal ion transport system permease component
AB984_RS06890	COG1464	Belongs to the NlpA lipoprotein family
AB984_RS06895	COG2502	aspartate--ammonia ligase
AB984_RS06910	COG0803	Belongs to the bacterial solute-binding protein 9 family
AB984_RS06920	COG2365	Tyrosine phosphatase family
AB984_RS06930	COG0577	efflux transmembrane transporter activity
AB984_RS06935	COG1136	(ABC) transporter
AB984_RS06950	COG0574	Belongs to the PEP-utilizing enzyme family
AB984_RS06950	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AB984_RS06960	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AB984_RS06970	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AB984_RS06980	COG4604	ABC transporter, ATP-binding protein
AB984_RS06985	COG4607	ABC-type enterochelin transport system periplasmic component
AB984_RS06990	COG1131	(ABC) transporter
AB984_RS07005	COG1132	(ABC) transporter
AB984_RS07010	COG1132	(ABC) transporter
AB984_RS07020	COG1187	pseudouridine synthase activity
AB984_RS07040	COG1136	(ABC) transporter
AB984_RS07065	COG1131	(ABC) transporter
AB984_RS07095	COG3716	PTS system mannose fructose sorbose family IID component
AB984_RS07100	COG3715	PTS system
AB984_RS07125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AB984_RS07125	COG1263	PTS System
AB984_RS07130	COG3711	transcriptional antiterminator
AB984_RS07145	COG0583	DNA-binding transcription factor activity
AB984_RS07155	COG0280	phosphate acetyltransferase
AB984_RS07185	COG1132	(ABC) transporter
AB984_RS07195	COG0789	Transcriptional regulator
AB984_RS07195	COG4978	Transcriptional regulator
AB984_RS07210	COG1288	antiporter activity
AB984_RS07215	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AB984_RS07230	COG0519	Catalyzes the synthesis of GMP from XMP
AB984_RS07245	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AB984_RS07255	COG2731	YhcH YjgK YiaL family protein
AB984_RS07270	COG2153	protein acetylation
AB984_RS07300	COG2267	carboxylic ester hydrolase activity
AB984_RS07305	COG0037	tRNA processing
AB984_RS07310	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AB984_RS07320	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AB984_RS07330	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AB984_RS07345	COG1442	glycosyl transferase family 8
AB984_RS07345	COG1216	Glycosyl transferase, family 2
AB984_RS07350	COG0438	transferase activity, transferring glycosyl groups
AB984_RS07355	COG1181	Belongs to the D-alanine--D-alanine ligase family
AB984_RS07360	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AB984_RS07365	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AB984_RS07385	COG1395	domain, Protein
AB984_RS07415	COG1136	(ABC) transporter
AB984_RS07485	COG2801	Transposase and inactivated derivatives
AB984_RS07500	COG1957	nucleoside hydrolase
AB984_RS07510	COG4603	Belongs to the binding-protein-dependent transport system permease family
AB984_RS07515	COG3845	ABC transporter
AB984_RS07525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AB984_RS07530	COG1609	Transcriptional regulator
AB984_RS07540	COG3012	SEC-C Motif Domain Protein
AB984_RS07545	COG0510	thiamine kinase activity
AB984_RS07565	COG0577	efflux transmembrane transporter activity
AB984_RS07565	COG1136	(ABC) transporter
AB984_RS07570	COG5002	protein histidine kinase activity
AB984_RS07575	COG0745	RESPONSE REGULATOR receiver
AB984_RS07630	COG1177	transmembrane transport
AB984_RS07640	COG3842	ATPase activity
AB984_RS07655	COG1597	lipid kinase activity
AB984_RS07660	COG1316	TRANSCRIPTIONal
AB984_RS07670	COG0622	Phosphoesterase
AB984_RS07675	COG1316	TRANSCRIPTIONal
AB984_RS07690	COG1131	(ABC) transporter
AB984_RS07695	COG1725	Transcriptional regulator
AB984_RS07700	COG0018	arginyl-trna synthetase
AB984_RS07705	COG1307	EDD domain protein, DegV family
AB984_RS07720	COG0583	DNA-binding transcription factor activity
AB984_RS07725	COG0076	glutamate decarboxylase activity
AB984_RS07740	COG0431	NADPH-dependent FMN reductase
AB984_RS07750	COG0765	amino acid transport
AB984_RS07760	COG0285	dihydrofolate synthase activity
AB984_RS07765	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AB984_RS07770	COG1316	TRANSCRIPTIONal
AB984_RS07780	COG1304	FMN binding
AB984_RS07800	COG0250	Participates in transcription elongation, termination and antitermination
AB984_RS07805	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AB984_RS07810	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AB984_RS07820	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AB984_RS07825	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AB984_RS07830	COG0215	cysteine-tRNA ligase activity
AB984_RS07855	COG1481	regulation of sporulation
AB984_RS07860	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AB984_RS07870	COG0492	ferredoxin-NADP+ reductase activity
AB984_RS07880	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AB984_RS07895	COG0556	nucleotide-excision repair
AB984_RS07900	COG0793	Belongs to the peptidase S41A family
AB984_RS07905	COG1611	Belongs to the LOG family
AB984_RS07915	COG0739	heme binding
AB984_RS07920	COG0739	heme binding
AB984_RS07925	COG2177	Part of the ABC transporter FtsEX involved in
AB984_RS07930	COG2884	Cell division ATP-binding protein ftsE
AB984_RS07935	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AB984_RS07945	COG0653	protein targeting
AB984_RS07985	COG2176	DNA-directed DNA polymerase activity
AB984_RS07990	COG0326	Molecular chaperone. Has ATPase activity
AB984_RS08010	COG1827	regulation of RNA biosynthetic process
AB984_RS08020	COG1393	Belongs to the ArsC family
AB984_RS08040	COG0081	regulation of translation
AB984_RS08045	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AB984_RS08060	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AB984_RS08070	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AB984_RS08075	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AB984_RS08080	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AB984_RS08095	COG0305	Participates in initiation and elongation during chromosome replication
AB984_RS08100	COG0359	binds to the 23S rRNA
AB984_RS08105	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
AB984_RS08115	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AB984_RS08120	COG0629	single-stranded DNA binding
AB984_RS08125	COG0360	Binds together with S18 to 16S ribosomal RNA
AB984_RS08130	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AB984_RS08135	COG0583	DNA-binding transcription factor activity
AB984_RS08145	COG2059	Chromate
AB984_RS08155	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AB984_RS08160	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AB984_RS08165	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AB984_RS08170	COG0037	tRNA processing
AB984_RS08180	COG1077	Cell shape determining protein MreB Mrl
AB984_RS08195	COG3142	Participates in the control of copper homeostasis
AB984_RS08200	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AB984_RS08210	COG0698	ribose 5-phosphate isomerase
AB984_RS08215	COG0009	L-threonylcarbamoyladenylate synthase
AB984_RS08220	COG2890	protein-(glutamine-N5) methyltransferase activity
AB984_RS08225	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AB984_RS08230	COG1435	thymidine kinase activity
AB984_RS08235	COG0254	rRNA binding
AB984_RS08270	COG2966	Psort location CytoplasmicMembrane, score
AB984_RS08275	COG1695	Transcriptional regulator
AB984_RS08295	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AB984_RS08305	COG1174	glycine betaine transport
AB984_RS08310	COG1174	glycine betaine transport
AB984_RS08315	COG1125	glycine betaine transport
AB984_RS08315	COG0517	IMP dehydrogenase activity
AB984_RS08320	COG2116	formate transmembrane transporter activity
AB984_RS08330	COG0504	CTP synthase activity
AB984_RS08345	COG0006	proline dipeptidase activity
AB984_RS08350	COG1078	dGTPase activity
AB984_RS08355	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AB984_RS08360	COG0183	Belongs to the thiolase family
AB984_RS08365	COG3425	synthase
AB984_RS08385	COG3870	Protein conserved in bacteria
AB984_RS08390	COG0012	GTP binding
AB984_RS08395	COG4481	Protein conserved in bacteria
AB984_RS08405	COG1490	D-aminoacyl-tRNA deacylase activity
AB984_RS08410	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AB984_RS08415	COG0604	alcohol dehydrogenase
AB984_RS08425	COG0708	Exodeoxyribonuclease III
AB984_RS08435	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AB984_RS08440	COG1074	ATP-dependent DNA helicase activity
AB984_RS08450	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AB984_RS08455	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AB984_RS08460	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AB984_RS08465	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AB984_RS08470	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AB984_RS08485	COG1012	belongs to the aldehyde dehydrogenase family
AB984_RS08495	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AB984_RS08500	COG2011	ABC-type metal ion transport system permease component
AB984_RS08505	COG1464	Belongs to the NlpA lipoprotein family
AB984_RS08510	COG0084	hydrolase, TatD family'
AB984_RS08520	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AB984_RS08535	COG1475	DNA binding
AB984_RS08540	COG1192	Involved in chromosome partitioning
AB984_RS08560	COG1217	gtp-binding protein TYPA
AB984_RS08570	COG0445	tRNA wobble uridine modification
AB984_RS08575	COG1725	Transcriptional regulator
AB984_RS08580	COG1131	(ABC) transporter
AB984_RS08590	COG0588	phosphoglycerate mutase activity
AB984_RS08610	COG0735	belongs to the Fur family
AB984_RS08615	COG0516	GMP reductase activity
AB984_RS08620	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AB984_RS08625	COG0470	DNA polymerase III
AB984_RS08630	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AB984_RS08640	COG0494	nUDIX hydrolase
AB984_RS08645	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
AB984_RS08655	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AB984_RS08660	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AB984_RS08665	COG0193	aminoacyl-tRNA hydrolase activity
AB984_RS08675	COG0706	membrane insertase activity
AB984_RS08680	COG0594	ribonuclease P activity