locus-tag	class	description
EKJ_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EKJ_RS00015	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EKJ_RS00025	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EKJ_RS00030	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EKJ_RS00040	COG1301	dicarboxylic acid transport
EKJ_RS00045	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EKJ_RS00065	COG0583	DNA-binding transcription factor activity
EKJ_RS00075	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EKJ_RS00080	COG0706	membrane insertase activity
EKJ_RS00085	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EKJ_RS00090	COG0594	ribonuclease P activity
EKJ_RS00095	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EKJ_RS00140	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EKJ_RS00150	COG0140	phosphoribosyl-ATP diphosphatase activity
EKJ_RS00155	COG0107	imidazoleglycerol-phosphate synthase activity
EKJ_RS00160	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EKJ_RS00165	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EKJ_RS00170	COG0131	Imidazoleglycerol-phosphate dehydratase
EKJ_RS00185	COG0194	GDP metabolic process
EKJ_RS00195	COG1028	Short-chain dehydrogenase reductase Sdr
EKJ_RS00200	COG1960	acyl-CoA dehydrogenase activity
EKJ_RS00205	COG1960	acyl-CoA dehydrogenase activity
EKJ_RS00215	COG2211	Major facilitator Superfamily
EKJ_RS00235	COG2171	N-acyltransferase activity
EKJ_RS00300	COG0657	acetylesterase activity
EKJ_RS00305	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EKJ_RS00325	COG1671	Belongs to the UPF0178 family
EKJ_RS00360	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EKJ_RS00395	COG1472	Belongs to the glycosyl hydrolase 3 family
EKJ_RS00410	COG1609	Transcriptional regulator
EKJ_RS00440	COG0330	HflC and HflK could
EKJ_RS00465	COG2070	2-Nitropropane dioxygenase
EKJ_RS00480	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EKJ_RS00485	COG0527	aspartate kinase activity
EKJ_RS00490	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EKJ_RS00495	COG0584	glycerophosphoryl diester phosphodiesterase
EKJ_RS00500	COG1393	Belongs to the ArsC family
EKJ_RS00505	COG4206	TonB-dependent receptor
EKJ_RS00510	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EKJ_RS00515	COG0217	transcriptional regulatory protein
EKJ_RS00525	COG0393	Putative heavy-metal-binding
EKJ_RS00530	COG1028	Short-chain dehydrogenase reductase Sdr
EKJ_RS00535	COG3750	Belongs to the UPF0335 family
EKJ_RS00545	COG0469	pyruvate kinase activity
EKJ_RS00565	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
EKJ_RS00565	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EKJ_RS00570	COG3300	MHYT domain
EKJ_RS00570	COG5001	Diguanylate cyclase
EKJ_RS00575	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EKJ_RS00580	COG0085	RNA polymerase activity
EKJ_RS00595	COG3655	Transcriptional regulator
EKJ_RS00605	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EKJ_RS00610	COG0222	ribosome binding
EKJ_RS00615	COG2076	Multidrug Resistance protein
EKJ_RS00620	COG0534	Mate efflux family protein
EKJ_RS00625	COG0668	transmembrane transport
EKJ_RS00630	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EKJ_RS00635	COG0459	protein refolding
EKJ_RS00675	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EKJ_RS00675	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EKJ_RS00680	COG3920	Histidine kinase
EKJ_RS00690	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EKJ_RS00705	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EKJ_RS00720	COG1250	3-hydroxyacyl-CoA dehydrogenase
EKJ_RS00740	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EKJ_RS00745	COG0280	phosphate acetyltransferase
EKJ_RS00745	COG0281	malic enzyme
EKJ_RS00765	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EKJ_RS00770	COG0730	response to heat
EKJ_RS00775	COG0668	transmembrane transport
EKJ_RS00785	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EKJ_RS00790	COG1137	ATPase activity
EKJ_RS00800	COG0312	modulator of DNA gyrase
EKJ_RS00805	COG0668	transmembrane transport
EKJ_RS00810	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EKJ_RS00815	COG0124	histidyl-tRNA synthetase
EKJ_RS00820	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EKJ_RS00825	COG2890	protein-(glutamine-N5) methyltransferase activity
EKJ_RS00835	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EKJ_RS00840	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EKJ_RS00845	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EKJ_RS00850	COG2070	2-Nitropropane dioxygenase
EKJ_RS00960	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EKJ_RS00965	COG3483	tryptophan 2,3-dioxygenase activity
EKJ_RS01020	COG0784	Response regulator, receiver
EKJ_RS01030	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EKJ_RS01035	COG0156	8-amino-7-oxononanoate synthase activity
EKJ_RS01045	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EKJ_RS01065	COG4695	Portal protein
EKJ_RS01145	COG2032	superoxide dismutase activity
EKJ_RS01155	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EKJ_RS01170	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EKJ_RS01175	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EKJ_RS01180	COG1278	Cold shock
EKJ_RS01185	COG1253	flavin adenine dinucleotide binding
EKJ_RS01195	COG1473	amidohydrolase
EKJ_RS01215	COG4771	TonB-dependent receptor
EKJ_RS01220	COG0004	ammonium transporteR
EKJ_RS01225	COG0347	Belongs to the P(II) protein family
EKJ_RS01235	COG2267	carboxylic ester hydrolase activity
EKJ_RS01240	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EKJ_RS01245	COG4221	oxidoreductase activity
EKJ_RS01250	COG0072	phenylalanine-tRNA ligase activity
EKJ_RS01255	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EKJ_RS01270	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EKJ_RS01275	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EKJ_RS01280	COG1028	Short-chain dehydrogenase reductase Sdr
EKJ_RS01300	COG1494	fructose-1,6-bisphosphatase
EKJ_RS01340	COG1201	RNA secondary structure unwinding
EKJ_RS01360	COG1192	Involved in chromosome partitioning
EKJ_RS01370	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EKJ_RS01390	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EKJ_RS01395	COG2857	Cytochrome c1
EKJ_RS01395	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EKJ_RS01400	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EKJ_RS01410	COG1496	oxidoreductase activity
EKJ_RS01415	COG0308	aminopeptidase N
EKJ_RS01420	COG0501	Belongs to the peptidase M48B family
EKJ_RS01455	COG1028	Short-chain dehydrogenase reductase Sdr
EKJ_RS01465	COG0588	phosphoglycerate mutase activity
EKJ_RS01470	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EKJ_RS01475	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EKJ_RS01485	COG0196	riboflavin kinase activity
EKJ_RS01490	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EKJ_RS01495	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EKJ_RS01505	COG1253	flavin adenine dinucleotide binding
EKJ_RS01515	COG1218	3'(2'),5'-bisphosphate nucleotidase
EKJ_RS01520	COG0045	succinate-CoA ligase (ADP-forming) activity
EKJ_RS01530	COG2086	electron transfer activity
EKJ_RS01540	COG2733	membrane
EKJ_RS01550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EKJ_RS01570	COG0482	sulfurtransferase activity
EKJ_RS01595	COG0259	pyridoxamine-phosphate oxidase activity
EKJ_RS01600	COG0484	heat shock protein binding
EKJ_RS01605	COG1295	ribonuclease BN
EKJ_RS01610	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EKJ_RS01615	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EKJ_RS01620	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EKJ_RS01630	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
EKJ_RS01640	COG0793	Belongs to the peptidase S41A family
EKJ_RS01650	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EKJ_RS01655	COG0799	negative regulation of ribosome biogenesis
EKJ_RS01660	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EKJ_RS01665	COG0739	heme binding
EKJ_RS01675	COG0318	PFAM AMP-dependent synthetase and ligase
EKJ_RS01685	COG0438	transferase activity, transferring glycosyl groups
EKJ_RS01720	COG1793	dna ligase
EKJ_RS01730	COG1872	DUF167
EKJ_RS01750	COG0113	porphobilinogen synthase activity
EKJ_RS01755	COG0739	heme binding
EKJ_RS01770	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EKJ_RS01780	COG1329	Transcriptional regulator
EKJ_RS01805	COG0009	L-threonylcarbamoyladenylate synthase
EKJ_RS01810	COG1960	acyl-CoA dehydrogenase activity
EKJ_RS01820	COG1956	GAF domain-containing protein
EKJ_RS01840	COG0357	Ribosomal RNA small subunit methyltransferase G
EKJ_RS01845	COG0445	tRNA wobble uridine modification
EKJ_RS01850	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EKJ_RS01865	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EKJ_RS01865	COG0069	glutamate synthase activity
EKJ_RS01875	COG3920	Histidine kinase
EKJ_RS01880	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EKJ_RS01890	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EKJ_RS01895	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EKJ_RS01900	COG0424	maF-like protein
EKJ_RS01905	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EKJ_RS01910	COG0237	dephospho-CoA kinase activity
EKJ_RS01915	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EKJ_RS01920	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EKJ_RS01935	COG3409	Peptidoglycan-binding domain 1 protein
EKJ_RS01935	COG3773	Cell wall hydrolase
EKJ_RS01945	COG0316	Belongs to the HesB IscA family
EKJ_RS01950	COG0517	IMP dehydrogenase activity
EKJ_RS01950	COG0516	GMP reductase activity
EKJ_RS01980	COG3275	phosphorelay sensor kinase activity
EKJ_RS02015	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EKJ_RS02020	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EKJ_RS02035	COG1612	heme a metabolic process
EKJ_RS02045	COG2022	thiamine diphosphate biosynthetic process
EKJ_RS02060	COG0387	Pfam Sodium calcium exchanger
EKJ_RS02065	COG1022	Amp-dependent synthetase and ligase
EKJ_RS02070	COG0405	Gamma-glutamyltransferase
EKJ_RS02075	COG0167	dihydroorotate dehydrogenase activity
EKJ_RS02090	COG0719	Fe-S assembly protein
EKJ_RS02100	COG0396	ATPase activity
EKJ_RS02110	COG0719	Fe-S assembly protein
EKJ_RS02115	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EKJ_RS02120	COG2151	metal-sulfur cluster biosynthetic enzyme
EKJ_RS02125	COG0316	Belongs to the HesB IscA family
EKJ_RS02145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EKJ_RS02150	COG0151	Belongs to the GarS family
EKJ_RS02155	COG1570	exodeoxyribonuclease VII activity
EKJ_RS02175	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EKJ_RS02180	COG0590	tRNA wobble adenosine to inosine editing
EKJ_RS02200	COG3279	Response regulator of the LytR AlgR family
EKJ_RS02205	COG2972	Histidine kinase
EKJ_RS02220	COG0501	Belongs to the peptidase M48B family
EKJ_RS02265	COG1228	amidohydrolase
EKJ_RS02295	COG0138	bifunctional purine biosynthesis protein purh
EKJ_RS02300	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EKJ_RS02310	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EKJ_RS02315	COG1024	Enoyl-CoA hydratase
EKJ_RS02325	COG0545	Peptidyl-prolyl cis-trans isomerase
EKJ_RS02335	COG1228	amidohydrolase
EKJ_RS02340	COG3104	oligopeptide transport
EKJ_RS02345	COG2188	Transcriptional regulator
EKJ_RS02350	COG0776	regulation of translation
EKJ_RS02380	COG4152	abc transporter atp-binding protein
EKJ_RS02385	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EKJ_RS02390	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EKJ_RS02405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EKJ_RS02425	COG4269	membrane
EKJ_RS02450	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EKJ_RS02460	COG2957	Belongs to the agmatine deiminase family
EKJ_RS02470	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EKJ_RS02475	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EKJ_RS02480	COG2833	Protein of unknown function (DUF455)
EKJ_RS02485	COG0739	heme binding
EKJ_RS02490	COG0318	PFAM AMP-dependent synthetase and ligase
EKJ_RS02505	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EKJ_RS02510	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EKJ_RS02525	COG1028	Short-chain dehydrogenase reductase Sdr
EKJ_RS02540	COG0495	leucyl-tRNA aminoacylation
EKJ_RS02565	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EKJ_RS02570	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EKJ_RS02580	COG1028	Short-chain dehydrogenase reductase Sdr
EKJ_RS02585	COG1024	Enoyl-CoA hydratase
EKJ_RS02595	COG0067	glutamate synthase
EKJ_RS02595	COG0069	glutamate synthase activity
EKJ_RS02595	COG0070	glutamate synthase
EKJ_RS02625	COG0183	Belongs to the thiolase family
EKJ_RS02635	COG1024	Enoyl-CoA hydratase
EKJ_RS02645	COG1132	(ABC) transporter
EKJ_RS02650	COG1968	undecaprenyl-diphosphatase activity
EKJ_RS02665	COG3186	Phenylalanine-4-hydroxylase
EKJ_RS02675	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
EKJ_RS02680	COG0183	Belongs to the thiolase family
EKJ_RS02685	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EKJ_RS02705	COG0514	ATP-dependent DNA helicase (RecQ)
EKJ_RS02735	COG3153	acetyltransferase
EKJ_RS02755	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EKJ_RS02765	COG0564	pseudouridine synthase activity
EKJ_RS02775	COG0433	COG0433 Predicted ATPase
EKJ_RS02780	COG2205	protein histidine kinase activity
EKJ_RS02820	COG0686	Belongs to the AlaDH PNT family
EKJ_RS02830	COG1674	ftsk spoiiie
EKJ_RS02845	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EKJ_RS02850	COG0318	PFAM AMP-dependent synthetase and ligase
EKJ_RS02855	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EKJ_RS02870	COG1125	glycine betaine transport
EKJ_RS02885	COG1960	acyl-CoA dehydrogenase activity
EKJ_RS02890	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EKJ_RS02910	COG0628	permease
EKJ_RS02920	COG1760	l-serine dehydratase
EKJ_RS02940	COG0519	Catalyzes the synthesis of GMP from XMP
EKJ_RS02940	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EKJ_RS02970	COG0312	modulator of DNA gyrase
EKJ_RS02980	COG1131	(ABC) transporter
EKJ_RS03025	COG2197	response regulator
EKJ_RS03040	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EKJ_RS03040	COG1372	Participates in initiation and elongation during chromosome replication
EKJ_RS03075	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EKJ_RS03080	COG0762	integral membrane protein
EKJ_RS03085	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EKJ_RS03095	COG2095	MarC family integral membrane protein
EKJ_RS03105	COG3118	belongs to the thioredoxin family
EKJ_RS03115	COG4771	TonB-dependent receptor
EKJ_RS03120	COG3268	Saccharopine dehydrogenase
EKJ_RS03130	COG0717	Belongs to the dCTP deaminase family
EKJ_RS03145	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EKJ_RS03180	COG0439	Biotin carboxylase
EKJ_RS03195	COG0864	Transcriptional regulator
EKJ_RS03200	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EKJ_RS03230	COG4771	TonB-dependent receptor
EKJ_RS03235	COG0457	Tetratricopeptide repeat
EKJ_RS03260	COG2884	Cell division ATP-binding protein ftsE
EKJ_RS03285	COG0287	Prephenate dehydrogenase
EKJ_RS03290	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EKJ_RS03295	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EKJ_RS03300	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EKJ_RS03300	COG2813	Specifically methylates the guanine in position
EKJ_RS03325	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EKJ_RS03330	COG2226	methyltransferase
EKJ_RS03335	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EKJ_RS03355	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EKJ_RS03360	COG0756	dUTP diphosphatase activity
EKJ_RS03370	COG0180	Tryptophanyl-tRNA synthetase
EKJ_RS03380	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EKJ_RS03385	COG4395	Tim44
EKJ_RS03395	COG2840	Smr protein MutS2
EKJ_RS03405	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EKJ_RS03410	COG3634	alkyl hydroperoxide reductase activity
EKJ_RS03415	COG0450	alkyl hydroperoxide reductase
EKJ_RS03420	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EKJ_RS03425	COG0632	four-way junction helicase activity
EKJ_RS03435	COG2255	four-way junction helicase activity
EKJ_RS03460	COG2989	Protein conserved in bacteria
EKJ_RS03475	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EKJ_RS03505	COG3220	belongs to the UPF0276 family
EKJ_RS03530	COG1605	Chorismate mutase
EKJ_RS03530	COG0077	Prephenate dehydratase
EKJ_RS03540	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EKJ_RS03570	COG4695	Portal protein
EKJ_RS03640	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EKJ_RS03650	COG2030	dehydratase
EKJ_RS03655	COG3932	Exopolysaccharide synthesis, ExoD
EKJ_RS03670	COG1758	RNA polymerase activity
EKJ_RS03675	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EKJ_RS03680	COG0305	Participates in initiation and elongation during chromosome replication
EKJ_RS03685	COG5328	Belongs to the UPF0262 family
EKJ_RS03700	COG1619	proteins homologs of microcin C7 resistance protein MccF
EKJ_RS03705	COG2866	Carboxypeptidase
EKJ_RS03720	COG0824	Thioesterase
EKJ_RS03740	COG0823	Involved in the tonB-independent uptake of proteins
EKJ_RS03745	COG2885	chlorophyll binding
EKJ_RS03770	COG0471	metal ion transport
EKJ_RS03775	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EKJ_RS03785	COG0408	coproporphyrinogen oxidase activity
EKJ_RS03845	COG1917	Cupin 2, conserved barrel domain protein
EKJ_RS03850	COG2271	Major facilitator Superfamily
EKJ_RS03855	COG1028	Short-chain dehydrogenase reductase Sdr
EKJ_RS03860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EKJ_RS03890	COG0745	RESPONSE REGULATOR receiver
EKJ_RS03895	COG2205	protein histidine kinase activity
EKJ_RS03950	COG0523	cobalamin synthesis protein
EKJ_RS03990	COG1136	(ABC) transporter
EKJ_RS04010	COG3290	protein histidine kinase activity
EKJ_RS04010	COG0840	transmembrane signaling receptor activity
EKJ_RS04020	COG4206	TonB-dependent receptor
EKJ_RS04030	COG1595	DNA-templated transcription, initiation
EKJ_RS04035	COG0612	Peptidase, M16
EKJ_RS04040	COG3706	GGDEF domain
EKJ_RS04055	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EKJ_RS04060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EKJ_RS04065	COG1309	transcriptional regulator
EKJ_RS04070	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EKJ_RS04080	COG2080	2 iron, 2 sulfur cluster binding
EKJ_RS04085	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EKJ_RS04090	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EKJ_RS04105	COG0438	transferase activity, transferring glycosyl groups
EKJ_RS04120	COG0297	glycogen (starch) synthase activity
EKJ_RS04140	COG2323	membrane
EKJ_RS04145	COG3665	Urea carboxylase-associated protein
EKJ_RS04165	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EKJ_RS04175	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EKJ_RS04180	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EKJ_RS04200	COG0798	PFAM Bile acid sodium symporter
EKJ_RS04210	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EKJ_RS04215	COG1472	Belongs to the glycosyl hydrolase 3 family
EKJ_RS04220	COG2226	methyltransferase
EKJ_RS04230	COG0646	methionine synthase
EKJ_RS04230	COG1410	methionine synthase
EKJ_RS04240	COG1410	methionine synthase
EKJ_RS04240	COG0646	methionine synthase
EKJ_RS04245	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EKJ_RS04250	COG0509	glycine decarboxylation via glycine cleavage system
EKJ_RS04255	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EKJ_RS04260	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EKJ_RS04295	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EKJ_RS04310	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EKJ_RS04315	COG4235	cytochrome complex assembly
EKJ_RS04340	COG1024	Enoyl-CoA hydratase
EKJ_RS04345	COG1024	Enoyl-CoA hydratase
EKJ_RS04405	COG0783	Belongs to the Dps family
EKJ_RS04430	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EKJ_RS04460	COG3713	MltA-interacting MipA family protein
EKJ_RS04480	COG1115	amino acid carrier protein
EKJ_RS04510	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EKJ_RS04515	COG0081	regulation of translation
EKJ_RS04535	COG1058	Belongs to the CinA family
EKJ_RS04535	COG1546	Belongs to the CinA family
EKJ_RS04540	COG2072	flavoprotein involved in K transport
EKJ_RS04545	COG1609	Transcriptional regulator
EKJ_RS04550	COG1228	amidohydrolase
EKJ_RS04565	COG3300	MHYT domain
EKJ_RS04565	COG5001	Diguanylate cyclase
EKJ_RS04570	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EKJ_RS04575	COG2201	protein-glutamate methylesterase activity
EKJ_RS04580	COG0745	RESPONSE REGULATOR receiver
EKJ_RS04590	COG0784	Response regulator, receiver
EKJ_RS04590	COG0643	Histidine kinase
EKJ_RS04590	COG2198	Histidine kinase
EKJ_RS04600	COG0235	Class ii aldolase
EKJ_RS04605	COG2080	2 iron, 2 sulfur cluster binding
EKJ_RS04620	COG1629	transport
EKJ_RS04620	COG4771	TonB-dependent receptor
EKJ_RS04625	COG1393	Belongs to the ArsC family
EKJ_RS04645	COG0321	lipoyl(octanoyl) transferase activity
EKJ_RS04660	COG1902	pentaerythritol trinitrate reductase activity
EKJ_RS04680	COG1505	serine-type exopeptidase activity
EKJ_RS04705	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EKJ_RS04740	COG0037	tRNA processing
EKJ_RS04750	COG0800	Aldolase
EKJ_RS04755	COG0837	glucose binding
EKJ_RS04760	COG0129	dihydroxy-acid dehydratase activity
EKJ_RS04765	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EKJ_RS04770	COG5001	Diguanylate cyclase
EKJ_RS04775	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EKJ_RS04790	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EKJ_RS04795	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EKJ_RS04805	COG4771	TonB-dependent receptor
EKJ_RS04810	COG1309	transcriptional regulator
EKJ_RS04820	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EKJ_RS04830	COG0457	Tetratricopeptide repeat
EKJ_RS04840	COG0616	signal peptide processing
EKJ_RS04845	COG0540	Belongs to the ATCase OTCase family
EKJ_RS04850	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EKJ_RS04875	COG2311	Membrane
EKJ_RS04900	COG1160	GTP binding
EKJ_RS04925	COG0544	peptidyl-prolyl cis-trans isomerase activity
EKJ_RS04940	COG0740	serine-type endopeptidase activity
EKJ_RS04945	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EKJ_RS04950	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EKJ_RS04960	COG1595	DNA-templated transcription, initiation
EKJ_RS04980	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EKJ_RS04985	COG0564	pseudouridine synthase activity
EKJ_RS05000	COG3023	N-Acetylmuramoyl-L-alanine amidase
EKJ_RS05010	COG5001	Diguanylate cyclase
EKJ_RS05010	COG3300	MHYT domain
EKJ_RS05025	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EKJ_RS05045	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EKJ_RS05060	COG0730	response to heat
EKJ_RS05080	COG0525	valine-tRNA ligase activity
EKJ_RS05085	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EKJ_RS05115	COG0546	phosphoglycolate phosphatase activity
EKJ_RS05130	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EKJ_RS05135	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EKJ_RS05150	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EKJ_RS05155	COG0154	amidase activity
EKJ_RS05165	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EKJ_RS05175	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EKJ_RS05185	COG0612	Peptidase, M16
EKJ_RS05200	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EKJ_RS05205	COG0542	response to heat
EKJ_RS05210	COG4771	TonB-dependent receptor
EKJ_RS05235	COG4206	TonB-dependent receptor
EKJ_RS05250	COG1024	Enoyl-CoA hydratase
EKJ_RS05280	COG4964	Belongs to the GSP D family
EKJ_RS05305	COG3422	double-strand break repair
EKJ_RS05310	COG0328	RNA-DNA hybrid ribonuclease activity
EKJ_RS05315	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EKJ_RS05320	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EKJ_RS05330	COG0018	arginyl-trna synthetase
EKJ_RS05340	COG1472	Belongs to the glycosyl hydrolase 3 family
EKJ_RS05345	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EKJ_RS05350	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EKJ_RS05355	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EKJ_RS05360	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EKJ_RS05365	COG0805	protein transport
EKJ_RS05370	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EKJ_RS05375	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EKJ_RS05380	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
EKJ_RS05385	COG0729	surface antigen
EKJ_RS05415	COG0174	glutamine synthetase
EKJ_RS05420	COG0347	Belongs to the P(II) protein family
EKJ_RS05425	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EKJ_RS05435	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EKJ_RS05445	COG0024	Methionine aminopeptidase
EKJ_RS05450	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EKJ_RS05455	COG4133	protoheme IX ABC transporter activity
EKJ_RS05460	COG2154	pterin-4-alpha-carbinolamine dehydratase
EKJ_RS05470	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EKJ_RS05480	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EKJ_RS05495	COG2001	Belongs to the MraZ family
EKJ_RS05500	COG0275	rRNA processing
EKJ_RS05515	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EKJ_RS05520	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EKJ_RS05525	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EKJ_RS05530	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EKJ_RS05540	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EKJ_RS05545	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EKJ_RS05550	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EKJ_RS05555	COG1181	Belongs to the D-alanine--D-alanine ligase family
EKJ_RS05560	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EKJ_RS05565	COG0849	cell division
EKJ_RS05570	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EKJ_RS05585	COG0670	Belongs to the BI1 family
EKJ_RS05600	COG2066	Belongs to the glutaminase family
EKJ_RS05610	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EKJ_RS05615	COG1695	Transcriptional regulator
EKJ_RS05635	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EKJ_RS05640	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EKJ_RS05650	COG1054	Belongs to the UPF0176 family
EKJ_RS05665	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EKJ_RS05680	COG1595	DNA-templated transcription, initiation
EKJ_RS05690	COG1648	precorrin-2 dehydrogenase activity
EKJ_RS05690	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EKJ_RS05695	COG0019	diaminopimelate decarboxylase activity
EKJ_RS05705	COG0165	Argininosuccinate lyase
EKJ_RS05710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EKJ_RS05720	COG0252	asparaginase activity
EKJ_RS05730	COG0101	tRNA pseudouridine synthase activity
EKJ_RS05735	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EKJ_RS05740	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EKJ_RS05750	COG0242	peptide deformylase activity
EKJ_RS05755	COG1322	Protein conserved in bacteria
EKJ_RS05760	COG3920	Histidine kinase
EKJ_RS05770	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EKJ_RS05780	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EKJ_RS05780	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EKJ_RS05785	COG1660	Displays ATPase and GTPase activities
EKJ_RS05795	COG2205	protein histidine kinase activity
EKJ_RS05800	COG0745	RESPONSE REGULATOR receiver
EKJ_RS05805	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EKJ_RS05815	COG0492	ferredoxin-NADP+ reductase activity
EKJ_RS05840	COG2945	thiolester hydrolase activity
EKJ_RS05845	COG1104	cysteine desulfurase activity
EKJ_RS05850	COG1104	cysteine desulfurase activity
EKJ_RS05860	COG0693	protein deglycase activity
EKJ_RS05870	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EKJ_RS05880	COG0617	tRNA 3'-terminal CCA addition
EKJ_RS05900	COG2133	pyrroloquinoline quinone binding
EKJ_RS05905	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EKJ_RS05915	COG1278	Cold shock
EKJ_RS05920	COG2189	Belongs to the N(4) N(6)-methyltransferase family
EKJ_RS05980	COG2267	carboxylic ester hydrolase activity
EKJ_RS05985	COG1794	racemase activity, acting on amino acids and derivatives
EKJ_RS05990	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EKJ_RS06040	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EKJ_RS06045	COG5001	Diguanylate cyclase
EKJ_RS06050	COG0047	phosphoribosylformylglycinamidine synthase activity
EKJ_RS06055	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EKJ_RS06060	COG4771	TonB-dependent receptor
EKJ_RS06065	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EKJ_RS06075	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EKJ_RS06080	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EKJ_RS06100	COG0424	maF-like protein
EKJ_RS06105	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EKJ_RS06115	COG2081	HI0933 family
EKJ_RS06125	COG0322	excinuclease ABC activity
EKJ_RS06135	COG2827	Endonuclease containing a URI domain
EKJ_RS06200	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
EKJ_RS06205	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EKJ_RS06210	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EKJ_RS06215	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EKJ_RS06220	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EKJ_RS06230	COG0596	Alpha beta hydrolase
EKJ_RS06235	COG1028	Short-chain dehydrogenase reductase Sdr
EKJ_RS06240	COG1741	Belongs to the pirin family
EKJ_RS06280	COG1733	regulation of RNA biosynthetic process
EKJ_RS06295	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EKJ_RS06320	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EKJ_RS06335	COG0681	Belongs to the peptidase S26 family
EKJ_RS06340	COG0736	holo-[acyl-carrier-protein] synthase activity
EKJ_RS06350	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EKJ_RS06355	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EKJ_RS06360	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EKJ_RS06365	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EKJ_RS06370	COG2267	carboxylic ester hydrolase activity
EKJ_RS06375	COG0109	protoheme IX farnesyltransferase activity
EKJ_RS06380	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
EKJ_RS06420	COG0314	molybdopterin synthase activity
EKJ_RS06435	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EKJ_RS06440	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EKJ_RS06460	COG0354	folic acid binding
EKJ_RS06465	COG0418	dihydroorotase activity
EKJ_RS06485	COG1012	belongs to the aldehyde dehydrogenase family
EKJ_RS06490	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EKJ_RS06535	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EKJ_RS06545	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EKJ_RS06550	COG0640	Transcriptional regulator
EKJ_RS06560	COG0789	Transcriptional regulator
EKJ_RS06590	COG1199	ATP-dependent helicase activity
EKJ_RS06590	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EKJ_RS06610	COG3920	Histidine kinase
EKJ_RS06635	COG1047	Peptidyl-prolyl cis-trans
EKJ_RS06640	COG3706	GGDEF domain
EKJ_RS06650	COG3706	GGDEF domain
EKJ_RS06655	COG0534	Mate efflux family protein
EKJ_RS06675	COG2205	protein histidine kinase activity
EKJ_RS06680	COG1522	sequence-specific DNA binding
EKJ_RS06700	COG0439	Biotin carboxylase
EKJ_RS06705	COG0511	ligase activity, forming carbon-carbon bonds
EKJ_RS06710	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EKJ_RS06755	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EKJ_RS06760	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EKJ_RS06765	COG0438	transferase activity, transferring glycosyl groups
EKJ_RS06780	COG1573	uracil-dna glycosylase
EKJ_RS06785	COG0488	(ABC) transporter
EKJ_RS06815	COG1605	Chorismate mutase
EKJ_RS06815	COG0287	Prephenate dehydrogenase
EKJ_RS06820	COG0142	geranyltranstransferase activity
EKJ_RS06825	COG1643	Atp-dependent helicase
EKJ_RS06845	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EKJ_RS06855	COG0776	regulation of translation
EKJ_RS06885	COG0688	phosphatidylethanolamine metabolic process
EKJ_RS06890	COG1183	phosphatidylcholine synthase activity
EKJ_RS06900	COG0052	Belongs to the universal ribosomal protein uS2 family
EKJ_RS06905	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EKJ_RS06910	COG0528	UMP kinase activity
EKJ_RS06915	COG0233	cytoplasmic translational termination
EKJ_RS06920	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EKJ_RS06930	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EKJ_RS06935	COG0750	zinc metalloprotease
EKJ_RS06940	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EKJ_RS06950	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EKJ_RS06955	COG0254	rRNA binding
EKJ_RS06975	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EKJ_RS06980	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
EKJ_RS06985	COG1138	Cytochrome C-type biogenesis protein
EKJ_RS07005	COG3158	transport of potassium into the cell
EKJ_RS07010	COG2917	probably involved in intracellular septation
EKJ_RS07015	COG0552	protein localization to endoplasmic reticulum
EKJ_RS07020	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EKJ_RS07025	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EKJ_RS07030	COG5001	Diguanylate cyclase
EKJ_RS07030	COG3300	MHYT domain
EKJ_RS07040	COG0028	Belongs to the TPP enzyme family
EKJ_RS07055	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EKJ_RS07070	COG0583	DNA-binding transcription factor activity
EKJ_RS07075	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EKJ_RS07085	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EKJ_RS07095	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EKJ_RS07100	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EKJ_RS07105	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EKJ_RS07125	COG4638	Rieske (2fe-2S)
EKJ_RS07140	COG3047	cAMP biosynthetic process
EKJ_RS07145	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EKJ_RS07195	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EKJ_RS07200	COG2076	Multidrug Resistance protein
EKJ_RS07210	COG4206	TonB-dependent receptor
EKJ_RS07250	COG2072	flavoprotein involved in K transport
EKJ_RS07265	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EKJ_RS07270	COG4957	zinc ion binding
EKJ_RS07275	COG0784	Response regulator, receiver
EKJ_RS07275	COG2205	protein histidine kinase activity
EKJ_RS07340	COG1462	curli production assembly transport component CsgG
EKJ_RS07385	COG5001	Diguanylate cyclase
EKJ_RS07390	COG0315	cyclic pyranopterin monophosphate synthase activity
EKJ_RS07395	COG0303	'Molybdopterin
EKJ_RS07410	COG2211	Major facilitator Superfamily
EKJ_RS07415	COG0625	glutathione transferase activity
EKJ_RS07440	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EKJ_RS07450	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EKJ_RS07455	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EKJ_RS07460	COG0346	lactoylglutathione lyase activity
EKJ_RS07470	COG1024	Enoyl-CoA hydratase
EKJ_RS07475	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EKJ_RS07475	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EKJ_RS07490	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EKJ_RS07500	COG3755	Protein conserved in bacteria
EKJ_RS07505	COG4770	biotin carboxylase activity
EKJ_RS07515	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EKJ_RS07520	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EKJ_RS07530	COG4974	Belongs to the 'phage' integrase family
EKJ_RS07535	COG0825	malonyl-CoA metabolic process
EKJ_RS07575	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EKJ_RS07580	COG0302	gtp cyclohydrolase
EKJ_RS07585	COG0678	peroxiredoxin activity
EKJ_RS07585	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EKJ_RS07590	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EKJ_RS07595	COG2205	protein histidine kinase activity
EKJ_RS07605	COG3178	'Phosphotransferase
EKJ_RS07610	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EKJ_RS07620	COG1074	ATP-dependent DNA helicase activity
EKJ_RS07630	COG0483	inositol monophosphate 1-phosphatase activity
EKJ_RS07635	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EKJ_RS07645	COG0653	protein targeting
EKJ_RS07665	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EKJ_RS07675	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EKJ_RS07685	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EKJ_RS07695	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EKJ_RS07705	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EKJ_RS07715	COG1082	Xylose isomerase domain protein TIM barrel
EKJ_RS07720	COG0366	Alpha amylase catalytic
EKJ_RS07750	COG0288	reversible hydration of carbon dioxide
EKJ_RS07760	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EKJ_RS07780	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EKJ_RS07805	COG2211	Major facilitator Superfamily
EKJ_RS07815	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EKJ_RS07835	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EKJ_RS07840	COG0126	phosphoglycerate kinase activity
EKJ_RS07865	COG3588	fructose-bisphosphate aldolase
EKJ_RS07875	COG0352	thiamine-phosphate diphosphorylase activity
EKJ_RS07880	COG1376	ErfK ybiS ycfS ynhG family protein
EKJ_RS07885	COG0739	heme binding
EKJ_RS07895	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EKJ_RS07905	COG0483	inositol monophosphate 1-phosphatase activity
EKJ_RS07915	COG0471	metal ion transport
EKJ_RS07915	COG3273	potassium ion transport
EKJ_RS07920	COG1473	amidohydrolase
EKJ_RS07945	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EKJ_RS07950	COG2205	protein histidine kinase activity
EKJ_RS07950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EKJ_RS07950	COG2198	Histidine kinase
EKJ_RS07950	COG0784	Response regulator, receiver
EKJ_RS07955	COG2204	response regulator
EKJ_RS07975	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EKJ_RS07980	COG0733	neurotransmitter:sodium symporter activity
EKJ_RS07985	COG0531	amino acid
EKJ_RS08010	COG1573	uracil-dna glycosylase
EKJ_RS08020	COG1280	lysine exporter protein (LysE YggA)
EKJ_RS08030	COG0745	RESPONSE REGULATOR receiver
EKJ_RS08035	COG0704	Plays a role in the regulation of phosphate uptake
EKJ_RS08040	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EKJ_RS08050	COG0573	inorganic phosphate transmembrane transporter activity
EKJ_RS08060	COG3746	phosphate-selective porin O and P
EKJ_RS08065	COG5002	protein histidine kinase activity
EKJ_RS08080	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EKJ_RS08105	COG3618	amidohydrolase
EKJ_RS08115	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EKJ_RS08125	COG0596	Alpha beta hydrolase
EKJ_RS08130	COG1304	FMN binding
EKJ_RS08140	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EKJ_RS08145	COG0440	acetolactate synthase activity
EKJ_RS08155	COG0028	Belongs to the TPP enzyme family
EKJ_RS08160	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EKJ_RS08165	COG0560	Phosphoserine phosphatase
EKJ_RS08185	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EKJ_RS08200	COG1722	exodeoxyribonuclease VII activity
EKJ_RS08205	COG0142	geranyltranstransferase activity
EKJ_RS08210	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EKJ_RS08220	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EKJ_RS08230	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
EKJ_RS08235	COG1131	(ABC) transporter
EKJ_RS08240	COG0842	Transport permease protein
EKJ_RS08250	COG0343	queuine tRNA-ribosyltransferase activity
EKJ_RS08260	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EKJ_RS08275	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EKJ_RS08285	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EKJ_RS08290	COG0698	ribose 5-phosphate isomerase
EKJ_RS08300	COG2202	Pas domain
EKJ_RS08300	COG3920	Histidine kinase
EKJ_RS08305	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EKJ_RS08330	COG0505	Belongs to the CarA family
EKJ_RS08345	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EKJ_RS08380	COG0148	phosphopyruvate hydratase activity
EKJ_RS08400	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EKJ_RS08420	COG2197	response regulator
EKJ_RS08425	COG0772	Belongs to the SEDS family
EKJ_RS08430	COG0768	penicillin binding
EKJ_RS08450	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EKJ_RS08460	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EKJ_RS08475	COG0012	GTP binding
EKJ_RS08485	COG2239	Acts as a magnesium transporter
EKJ_RS08495	COG0193	aminoacyl-tRNA hydrolase activity
EKJ_RS08500	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EKJ_RS08515	COG0752	glycyl-tRNA synthetase alpha subunit
EKJ_RS08525	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EKJ_RS08525	COG0574	Belongs to the PEP-utilizing enzyme family
EKJ_RS08530	COG2226	methyltransferase
EKJ_RS08535	COG1040	competence protein
EKJ_RS08540	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EKJ_RS08545	COG0789	Transcriptional regulator
EKJ_RS08550	COG1960	acyl-CoA dehydrogenase activity
EKJ_RS08575	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EKJ_RS08585	COG3876	Protein conserved in bacteria
EKJ_RS08590	COG2814	Major facilitator Superfamily
EKJ_RS08605	COG0840	transmembrane signaling receptor activity
EKJ_RS08610	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EKJ_RS08620	COG0187	DNA topoisomerase II activity
EKJ_RS08630	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EKJ_RS08635	COG0792	nuclease activity
EKJ_RS08640	COG0189	ligase activity
EKJ_RS08645	COG0586	Pfam SNARE associated Golgi protein
EKJ_RS08655	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EKJ_RS08665	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EKJ_RS08670	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EKJ_RS08675	COG1420	regulation of RNA biosynthetic process
EKJ_RS08680	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EKJ_RS08705	COG0443	Heat shock 70 kDa protein
EKJ_RS08710	COG0484	heat shock protein binding
EKJ_RS08720	COG1752	Esterase of the alpha-beta hydrolase superfamily
EKJ_RS08745	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EKJ_RS08755	COG0442	prolyl-tRNA aminoacylation
EKJ_RS08775	COG0508	dehydrogenase complex catalyzes the overall conversion of
EKJ_RS08790	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EKJ_RS08810	COG2951	lytic endotransglycosylase activity
EKJ_RS08815	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EKJ_RS08820	COG1686	Belongs to the peptidase S11 family
EKJ_RS08825	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EKJ_RS08840	COG0084	hydrolase, TatD family'
EKJ_RS08850	COG3956	TIGRFAM MazG family protein
EKJ_RS08855	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EKJ_RS08860	COG1923	regulation of RNA biosynthetic process
EKJ_RS08865	COG2204	response regulator
EKJ_RS08890	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EKJ_RS08890	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EKJ_RS08900	COG1546	Belongs to the CinA family
EKJ_RS08900	COG1058	Belongs to the CinA family
EKJ_RS08905	COG2867	negative regulation of translational initiation
EKJ_RS08910	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EKJ_RS08915	COG0288	reversible hydration of carbon dioxide
EKJ_RS08930	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EKJ_RS08940	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EKJ_RS08955	COG0022	dehydrogenase e1 component
EKJ_RS08955	COG0508	dehydrogenase complex catalyzes the overall conversion of
EKJ_RS08960	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EKJ_RS08975	COG0346	lactoylglutathione lyase activity
EKJ_RS08980	COG0668	transmembrane transport
EKJ_RS08985	COG0596	Alpha beta hydrolase
EKJ_RS09005	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EKJ_RS09015	COG0071	Belongs to the small heat shock protein (HSP20) family
EKJ_RS09020	COG0504	CTP synthase activity
EKJ_RS09030	COG0149	triose-phosphate isomerase activity
EKJ_RS09040	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EKJ_RS09060	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EKJ_RS09065	COG0134	indole-3-glycerol-phosphate synthase activity
EKJ_RS09070	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EKJ_RS09075	COG2333	competence protein COMEC
EKJ_RS09075	COG0658	competence protein
EKJ_RS09080	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EKJ_RS09085	COG0372	Belongs to the citrate synthase family
EKJ_RS09090	COG2205	protein histidine kinase activity
EKJ_RS09120	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EKJ_RS09130	COG1007	ATP synthesis coupled electron transport
EKJ_RS09145	COG0713	ATP synthesis coupled electron transport
EKJ_RS09155	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EKJ_RS09160	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EKJ_RS09165	COG1034	ATP synthesis coupled electron transport
EKJ_RS09170	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EKJ_RS09175	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EKJ_RS09180	COG0649	NAD binding
EKJ_RS09190	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EKJ_RS09195	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EKJ_RS09200	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EKJ_RS09205	COG1012	belongs to the aldehyde dehydrogenase family
EKJ_RS09210	COG0183	Belongs to the thiolase family
EKJ_RS09235	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EKJ_RS09240	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EKJ_RS09245	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EKJ_RS09275	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EKJ_RS09280	COG0860	N-Acetylmuramoyl-L-alanine amidase
EKJ_RS09285	COG1530	ribonuclease E activity
EKJ_RS09290	COG2226	methyltransferase
EKJ_RS09305	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EKJ_RS09315	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EKJ_RS09325	COG0367	asparagine synthase
EKJ_RS09350	COG3267	Type II secretory pathway component ExeA
EKJ_RS09350	COG3409	Peptidoglycan-binding domain 1 protein
EKJ_RS09405	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EKJ_RS09410	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EKJ_RS09410	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EKJ_RS09420	COG0129	dihydroxy-acid dehydratase activity
EKJ_RS09430	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EKJ_RS09450	COG0521	Mo-molybdopterin cofactor biosynthetic process
EKJ_RS09480	COG1136	(ABC) transporter
EKJ_RS09490	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EKJ_RS09495	COG1028	Short-chain dehydrogenase reductase Sdr
EKJ_RS09510	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EKJ_RS09515	COG0415	Belongs to the DNA photolyase family
EKJ_RS09530	COG1013	pyruvate-flavodoxin oxidoreductase activity
EKJ_RS09535	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EKJ_RS09535	COG0674	pyruvate-flavodoxin oxidoreductase activity
EKJ_RS09540	COG0657	acetylesterase activity
EKJ_RS09545	COG1051	belongs to the nudix hydrolase family
EKJ_RS09555	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EKJ_RS09555	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EKJ_RS09575	COG0604	alcohol dehydrogenase
EKJ_RS09585	COG1028	Short-chain dehydrogenase reductase Sdr
EKJ_RS09590	COG2321	neutral zinc metallopeptidase
EKJ_RS09600	COG3682	Transcriptional regulator
EKJ_RS09625	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EKJ_RS09635	COG1028	Short-chain dehydrogenase reductase Sdr
EKJ_RS09645	COG2264	protein methyltransferase activity
EKJ_RS09665	COG4221	oxidoreductase activity
EKJ_RS09675	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EKJ_RS09685	COG3706	GGDEF domain
EKJ_RS09690	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EKJ_RS09695	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EKJ_RS09705	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EKJ_RS09750	COG1937	Protein conserved in bacteria
EKJ_RS09755	COG2132	Multicopper oxidase
EKJ_RS09765	COG0481	GTPase activity
EKJ_RS09770	COG5001	Diguanylate cyclase
EKJ_RS09770	COG3300	MHYT domain
EKJ_RS09775	COG0493	'glutamate synthase
EKJ_RS09780	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
EKJ_RS09805	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EKJ_RS09810	COG1619	proteins homologs of microcin C7 resistance protein MccF
EKJ_RS09815	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EKJ_RS09825	COG2354	Protein conserved in bacteria
EKJ_RS09830	COG0360	Binds together with S18 to 16S ribosomal RNA
EKJ_RS09835	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EKJ_RS09840	COG0359	binds to the 23S rRNA
EKJ_RS09845	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EKJ_RS09865	COG0189	ligase activity
EKJ_RS09870	COG0189	ligase activity
EKJ_RS09870	COG4067	protein conserved in archaea
EKJ_RS09905	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EKJ_RS09915	COG0335	large ribosomal subunit rRNA binding
EKJ_RS09920	COG0336	Belongs to the RNA methyltransferase TrmD family
EKJ_RS09930	COG0492	ferredoxin-NADP+ reductase activity
EKJ_RS09945	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EKJ_RS09950	COG0228	four-way junction DNA binding
EKJ_RS09955	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EKJ_RS09970	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EKJ_RS09980	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EKJ_RS09990	COG0539	negative regulation of cytoplasmic translation
EKJ_RS09995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EKJ_RS10000	COG1028	Short-chain dehydrogenase reductase Sdr
EKJ_RS10000	COG0604	alcohol dehydrogenase
EKJ_RS10000	COG3321	synthase
EKJ_RS10005	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EKJ_RS10010	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EKJ_RS10015	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EKJ_RS10020	COG0356	it plays a direct role in the translocation of protons across the membrane
EKJ_RS10045	COG2003	Belongs to the UPF0758 family
EKJ_RS10055	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EKJ_RS10065	COG0284	orotidine-5'-phosphate decarboxylase activity
EKJ_RS10070	COG0135	phosphoribosylanthranilate isomerase activity
EKJ_RS10075	COG0133	tryptophan synthase activity
EKJ_RS10080	COG0159	tryptophan synthase activity
EKJ_RS10085	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EKJ_RS10090	COG0285	dihydrofolate synthase activity
EKJ_RS10095	COG2223	nitrite transmembrane transporter activity
EKJ_RS10105	COG1187	pseudouridine synthase activity
EKJ_RS10110	COG0742	ribosomal rna small subunit methyltransferase
EKJ_RS10125	COG0210	DNA helicase
EKJ_RS10135	COG0513	Belongs to the DEAD box helicase family
EKJ_RS10145	COG0277	FAD linked oxidase domain protein
EKJ_RS10165	COG1482	cell wall glycoprotein biosynthetic process
EKJ_RS10215	COG0438	transferase activity, transferring glycosyl groups
EKJ_RS10240	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EKJ_RS10245	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EKJ_RS10250	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EKJ_RS10260	COG0538	isocitrate dehydrogenase activity
EKJ_RS10265	COG3153	acetyltransferase
EKJ_RS10265	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EKJ_RS10270	COG0475	glutathione-regulated potassium exporter activity
EKJ_RS10270	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EKJ_RS10285	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EKJ_RS10290	COG4106	trans-aconitate 2-methyltransferase activity
EKJ_RS10295	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EKJ_RS10300	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EKJ_RS10310	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EKJ_RS10325	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EKJ_RS10335	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EKJ_RS10340	COG0741	lytic transglycosylase activity
EKJ_RS10360	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EKJ_RS10370	COG2258	MOSC domain
EKJ_RS10390	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EKJ_RS10405	COG0137	argininosuccinate synthase activity
EKJ_RS10410	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EKJ_RS10415	COG4566	intracellular signal transduction
EKJ_RS10420	COG2197	response regulator
EKJ_RS10440	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EKJ_RS10445	COG3706	GGDEF domain
EKJ_RS10455	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EKJ_RS10465	COG0339	signal peptide processing
EKJ_RS10470	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EKJ_RS10475	COG4139	cobalamin transport
EKJ_RS10485	COG4206	TonB-dependent receptor
EKJ_RS10500	COG0039	L-malate dehydrogenase activity
EKJ_RS10510	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EKJ_RS10520	COG0508	dehydrogenase complex catalyzes the overall conversion of
EKJ_RS10525	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EKJ_RS10555	COG2860	membrane
EKJ_RS10575	COG0203	ribosomal protein L17
EKJ_RS10580	COG0202	RNA polymerase activity
EKJ_RS10585	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EKJ_RS10590	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EKJ_RS10595	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EKJ_RS10605	COG0563	adenylate kinase activity
EKJ_RS10610	COG0201	protein transport
EKJ_RS10615	COG0200	Binds to the 23S rRNA
EKJ_RS10625	COG1841	ribosomal large subunit assembly
EKJ_RS10630	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EKJ_RS10635	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EKJ_RS10640	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EKJ_RS10645	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EKJ_RS10650	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EKJ_RS10655	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EKJ_RS10660	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EKJ_RS10665	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EKJ_RS10670	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EKJ_RS10675	COG0255	Belongs to the universal ribosomal protein uL29 family
EKJ_RS10680	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EKJ_RS10685	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EKJ_RS10690	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EKJ_RS10695	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EKJ_RS10700	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EKJ_RS10705	COG0089	rRNA binding
EKJ_RS10710	COG0088	Forms part of the polypeptide exit tunnel
EKJ_RS10715	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EKJ_RS10720	COG0051	transcription antitermination factor activity, RNA binding
EKJ_RS10725	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EKJ_RS10730	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EKJ_RS10735	COG0049	tRNA binding
EKJ_RS10740	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EKJ_RS10810	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EKJ_RS10820	COG2967	ApaG domain
EKJ_RS10875	COG0473	3-isopropylmalate dehydrogenase activity
EKJ_RS10880	COG1381	Involved in DNA repair and RecF pathway recombination
EKJ_RS10890	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
EKJ_RS10895	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EKJ_RS10925	COG0513	Belongs to the DEAD box helicase family
EKJ_RS10935	COG0166	Belongs to the GPI family
EKJ_RS10940	COG0681	Belongs to the peptidase S26 family
EKJ_RS10945	COG0571	ribonuclease III activity
EKJ_RS10950	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EKJ_RS10960	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EKJ_RS10960	COG1754	DNA topoisomerase type I activity
EKJ_RS10970	COG0758	DNA mediated transformation
EKJ_RS10975	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EKJ_RS10980	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EKJ_RS10985	COG0156	8-amino-7-oxononanoate synthase activity
EKJ_RS11010	COG0625	glutathione transferase activity
EKJ_RS11035	COG1748	Saccharopine dehydrogenase
EKJ_RS11065	COG0492	ferredoxin-NADP+ reductase activity
EKJ_RS11075	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
EKJ_RS11080	COG3387	PFAM Glycoside hydrolase 15-related
EKJ_RS11085	COG1877	trehalose-phosphatase activity
EKJ_RS11095	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
EKJ_RS11100	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EKJ_RS11105	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
EKJ_RS11110	COG0612	Peptidase, M16
EKJ_RS11115	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EKJ_RS11135	COG4957	zinc ion binding
EKJ_RS11145	COG0204	Acyl-transferase
EKJ_RS11150	COG0583	DNA-binding transcription factor activity
EKJ_RS11155	COG1253	flavin adenine dinucleotide binding
EKJ_RS11160	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EKJ_RS11165	COG1702	phosphate starvation-inducible protein PhoH
EKJ_RS11170	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EKJ_RS11185	COG2239	Acts as a magnesium transporter
EKJ_RS11210	COG2816	NAD+ diphosphatase activity
EKJ_RS11245	COG1196	nuclear chromosome segregation
EKJ_RS11260	COG0776	regulation of translation
EKJ_RS11265	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EKJ_RS11270	COG0416	fatty acid biosynthetic process
EKJ_RS11275	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EKJ_RS11285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EKJ_RS11310	COG0625	glutathione transferase activity
EKJ_RS11325	COG1733	regulation of RNA biosynthetic process
EKJ_RS11330	COG1012	belongs to the aldehyde dehydrogenase family
EKJ_RS11335	COG0028	Belongs to the TPP enzyme family
EKJ_RS11350	COG0215	cysteine-tRNA ligase activity
EKJ_RS11365	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EKJ_RS11385	COG1058	Belongs to the CinA family
EKJ_RS11385	COG1546	Belongs to the CinA family
EKJ_RS11390	COG1733	regulation of RNA biosynthetic process
EKJ_RS11400	COG3046	protein related to deoxyribodipyrimidine photolyase
EKJ_RS11410	COG2375	cellular response to nickel ion
EKJ_RS11420	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EKJ_RS11420	COG2169	Transcriptional regulator
EKJ_RS11425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EKJ_RS11435	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EKJ_RS11440	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EKJ_RS11445	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EKJ_RS11455	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EKJ_RS11460	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EKJ_RS11470	COG1505	serine-type exopeptidase activity
EKJ_RS11485	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EKJ_RS11495	COG1028	Short-chain dehydrogenase reductase Sdr
EKJ_RS11505	COG1045	serine acetyltransferase
EKJ_RS11520	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EKJ_RS11525	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EKJ_RS11540	COG0105	UTP biosynthetic process
EKJ_RS11560	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EKJ_RS11570	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EKJ_RS11575	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EKJ_RS11580	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EKJ_RS11585	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EKJ_RS11600	COG3724	N-succinylarginine dihydrolase activity
EKJ_RS11615	COG1970	mechanosensitive ion channel activity
EKJ_RS11625	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
EKJ_RS11655	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EKJ_RS11665	COG4181	ATPase activity
EKJ_RS11675	COG4771	TonB-dependent receptor
EKJ_RS11680	COG1217	gtp-binding protein TYPA
EKJ_RS11690	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EKJ_RS11695	COG0405	Gamma-glutamyltransferase
EKJ_RS11710	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EKJ_RS11710	COG2226	methyltransferase
EKJ_RS11710	COG0596	Alpha beta hydrolase
EKJ_RS11720	COG0556	nucleotide-excision repair
EKJ_RS11740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EKJ_RS11755	COG0181	hydroxymethylbilane synthase activity
EKJ_RS11760	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EKJ_RS11765	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EKJ_RS11775	COG2304	oxidoreductase activity
EKJ_RS11800	COG1960	acyl-CoA dehydrogenase activity
EKJ_RS11820	COG1960	acyl-CoA dehydrogenase activity
EKJ_RS11825	COG1024	Enoyl-CoA hydratase
EKJ_RS11830	COG0183	Belongs to the thiolase family
EKJ_RS11835	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EKJ_RS11840	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EKJ_RS11845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EKJ_RS11855	COG0175	sulfate reduction
EKJ_RS11865	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EKJ_RS11875	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EKJ_RS11875	COG1648	precorrin-2 dehydrogenase activity
EKJ_RS11885	COG0626	cystathionine gamma-synthase activity
EKJ_RS11890	COG2897	thiosulfate sulfurtransferase activity
EKJ_RS11900	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EKJ_RS11925	COG1733	regulation of RNA biosynthetic process
EKJ_RS11930	COG2223	nitrite transmembrane transporter activity
EKJ_RS11955	COG0183	Belongs to the thiolase family
EKJ_RS11960	COG2070	2-Nitropropane dioxygenase
EKJ_RS11975	COG0318	PFAM AMP-dependent synthetase and ligase
EKJ_RS11985	COG0183	Belongs to the thiolase family
EKJ_RS12070	COG4957	zinc ion binding
EKJ_RS12075	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EKJ_RS12115	COG0582	viral genome integration into host DNA
EKJ_RS12130	COG0842	Transport permease protein
EKJ_RS12155	COG1185	polyribonucleotide nucleotidyltransferase activity
EKJ_RS12160	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EKJ_RS12165	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EKJ_RS12170	COG1994	Peptidase M50
EKJ_RS12175	COG1435	thymidine kinase activity
EKJ_RS12180	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
EKJ_RS12185	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EKJ_RS12205	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EKJ_RS12220	COG0779	Required for maturation of 30S ribosomal subunits
EKJ_RS12225	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EKJ_RS12230	COG1842	Phage shock protein A
EKJ_RS12275	COG2166	iron-sulfur cluster assembly
EKJ_RS12280	COG2832	Protein of unknown function (DUF454)
EKJ_RS12295	COG0824	Thioesterase
EKJ_RS12300	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EKJ_RS12315	COG0066	3-isopropylmalate dehydratase activity
EKJ_RS12320	COG0604	alcohol dehydrogenase
EKJ_RS12320	COG3321	synthase
EKJ_RS12320	COG1028	Short-chain dehydrogenase reductase Sdr
EKJ_RS12335	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EKJ_RS12375	COG2198	Histidine kinase
EKJ_RS12375	COG5002	protein histidine kinase activity
EKJ_RS12375	COG0784	Response regulator, receiver
EKJ_RS12390	COG4771	TonB-dependent receptor
EKJ_RS12395	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
EKJ_RS12415	COG3451	type IV secretory pathway VirB4
EKJ_RS12430	COG0739	heme binding
EKJ_RS12430	COG1196	nuclear chromosome segregation
EKJ_RS12430	COG0741	lytic transglycosylase activity
EKJ_RS12460	COG0745	RESPONSE REGULATOR receiver
EKJ_RS12465	COG0667	Aldo Keto reductase
EKJ_RS12470	COG1028	Short-chain dehydrogenase reductase Sdr
EKJ_RS12475	COG1960	acyl-CoA dehydrogenase activity
EKJ_RS12490	COG1218	3'(2'),5'-bisphosphate nucleotidase
EKJ_RS12495	COG2301	Belongs to the HpcH HpaI aldolase family
EKJ_RS12500	COG1960	acyl-CoA dehydrogenase activity
EKJ_RS12520	COG0318	PFAM AMP-dependent synthetase and ligase
EKJ_RS12530	COG1024	Enoyl-CoA hydratase
EKJ_RS12530	COG1250	3-hydroxyacyl-CoA dehydrogenase
EKJ_RS12540	COG4771	TonB-dependent receptor
EKJ_RS12545	COG1538	Outer membrane efflux protein
EKJ_RS12555	COG1136	(ABC) transporter
EKJ_RS12555	COG4591	ABC-type transport system involved in lipoprotein release permease component
EKJ_RS12565	COG1309	transcriptional regulator
EKJ_RS12570	COG0784	Response regulator, receiver
EKJ_RS12570	COG2205	protein histidine kinase activity
EKJ_RS12585	COG1462	curli production assembly transport component CsgG
EKJ_RS12600	COG2204	response regulator
EKJ_RS12605	COG1360	Flagellar Motor Protein
EKJ_RS12610	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EKJ_RS12620	COG4786	Flagellar basal body rod
EKJ_RS12620	COG1256	bacterial-type flagellum assembly
EKJ_RS12630	COG1706	bacterial-type flagellum-dependent cell motility
EKJ_RS12635	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EKJ_RS12650	COG4786	Flagellar basal body rod
EKJ_RS12655	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EKJ_RS12670	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EKJ_RS12720	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EKJ_RS12735	COG1987	bacterial-type flagellum assembly
EKJ_RS12785	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EKJ_RS12795	COG1677	Flagellar hook-basal body complex protein FliE
EKJ_RS12805	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EKJ_RS12860	COG5265	(ABC) transporter
EKJ_RS12865	COG0659	secondary active sulfate transmembrane transporter activity
EKJ_RS12880	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EKJ_RS12885	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EKJ_RS12925	COG0629	single-stranded DNA binding
EKJ_RS12950	COG1999	signal sequence binding
EKJ_RS12955	COG2983	Belongs to the UPF0260 family
EKJ_RS12970	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EKJ_RS12970	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EKJ_RS12995	COG1448	Aminotransferase
EKJ_RS13010	COG0246	Mannitol dehydrogenase
EKJ_RS13015	COG1904	glucuronate isomerase
EKJ_RS13020	COG2721	sulfolactate sulfo-lyase activity
EKJ_RS13035	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EKJ_RS13040	COG3507	Belongs to the glycosyl hydrolase 43 family
EKJ_RS13070	COG1028	Short-chain dehydrogenase reductase Sdr
EKJ_RS13080	COG1609	Transcriptional regulator
EKJ_RS13100	COG3128	pkhd-type hydroxylase
EKJ_RS13105	COG4774	siderophore transport
EKJ_RS13115	COG0848	biopolymer transport protein
EKJ_RS13125	COG0640	Transcriptional regulator
EKJ_RS13130	COG0450	alkyl hydroperoxide reductase
EKJ_RS13170	COG1294	oxidase, subunit
EKJ_RS13185	COG4566	intracellular signal transduction
EKJ_RS13190	COG0784	Response regulator, receiver
EKJ_RS13190	COG4191	Histidine kinase
EKJ_RS13210	COG1960	acyl-CoA dehydrogenase activity
EKJ_RS13225	COG0175	sulfate reduction
EKJ_RS13255	COG1960	acyl-CoA dehydrogenase activity
EKJ_RS13260	COG1960	acyl-CoA dehydrogenase activity
EKJ_RS13270	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EKJ_RS13275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EKJ_RS13340	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EKJ_RS13400	COG0688	phosphatidylethanolamine metabolic process
EKJ_RS13415	COG0436	Aminotransferase
EKJ_RS13420	COG3243	poly(R)-hydroxyalkanoic acid synthase
EKJ_RS13460	COG0745	RESPONSE REGULATOR receiver
EKJ_RS13470	COG0784	Response regulator, receiver
EKJ_RS13475	COG3920	Histidine kinase
EKJ_RS13495	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EKJ_RS13500	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EKJ_RS13505	COG3813	Protein conserved in bacteria
EKJ_RS13510	COG0351	phosphomethylpyrimidine kinase
EKJ_RS13510	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EKJ_RS13510	COG0352	thiamine-phosphate diphosphorylase activity
EKJ_RS13525	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EKJ_RS13530	COG4765	Protein conserved in bacteria
EKJ_RS13550	COG0318	PFAM AMP-dependent synthetase and ligase
EKJ_RS13595	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EKJ_RS13610	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
EKJ_RS13625	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EKJ_RS13635	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EKJ_RS13640	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EKJ_RS13640	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EKJ_RS13650	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EKJ_RS13655	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
EKJ_RS13665	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EKJ_RS13665	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EKJ_RS13680	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EKJ_RS13685	COG2010	Cytochrome c
EKJ_RS13685	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EKJ_RS13690	COG0489	protein tyrosine kinase activity
EKJ_RS13705	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EKJ_RS13710	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EKJ_RS13715	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EKJ_RS13720	COG0268	Binds directly to 16S ribosomal RNA