locus-tag	class	description
AYN53_RS00005	COG3188	usher protein
AYN53_RS00010	COG3539	Fimbrial protein
AYN53_RS00015	COG3539	Fimbrial protein
AYN53_RS00020	COG3539	Fimbrial protein
AYN53_RS00025	COG2610	gluconate transmembrane transporter activity
AYN53_RS00035	COG0246	Mannitol dehydrogenase
AYN53_RS00040	COG2186	Transcriptional regulator
AYN53_RS00055	COG3518	anti-sigma factor antagonist activity
AYN53_RS00060	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AYN53_RS00065	COG0700	Nucleoside recognition
AYN53_RS00070	COG3366	ferrous iron transmembrane transporter activity
AYN53_RS00085	COG1924	4 iron, 4 sulfur cluster binding
AYN53_RS00090	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
AYN53_RS00095	COG2733	membrane
AYN53_RS00125	COG1401	restriction endodeoxyribonuclease activity
AYN53_RS00140	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AYN53_RS00145	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
AYN53_RS00150	COG1715	Restriction endonuclease
AYN53_RS00155	COG0523	cobalamin synthesis protein
AYN53_RS00160	COG2879	small protein
AYN53_RS00165	COG1966	Carbon starvation protein
AYN53_RS00180	COG2271	Major facilitator Superfamily
AYN53_RS00185	COG1802	Transcriptional regulator
AYN53_RS00190	COG1063	alcohol dehydrogenase
AYN53_RS00205	COG1484	DNA-dependent DNA replication
AYN53_RS00220	COG2966	Psort location CytoplasmicMembrane, score
AYN53_RS00240	COG2197	response regulator
AYN53_RS00245	COG4114	ferric iron reductase
AYN53_RS00275	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
AYN53_RS00280	COG0456	acetyltransferase
AYN53_RS00285	COG1011	Hydrolase
AYN53_RS00330	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AYN53_RS00335	COG5532	Uncharacterized conserved protein (DUF2303)
AYN53_RS00355	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AYN53_RS00360	COG4197	protein conserved in bacteria, prophage-related
AYN53_RS00375	COG1846	Transcriptional regulator
AYN53_RS00385	COG4725	Belongs to the MT-A70-like family
AYN53_RS00390	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
AYN53_RS00400	COG1403	HNH endonuclease
AYN53_RS00405	COG0484	heat shock protein binding
AYN53_RS00410	COG1278	Cold shock
AYN53_RS00420	COG3772	lysozyme
AYN53_RS00430	COG3646	Phage regulatory protein
AYN53_RS00460	COG0740	serine-type endopeptidase activity
AYN53_RS00540	COG5301	cellulose 1,4-beta-cellobiosidase activity
AYN53_RS00540	COG5301	cellulose 1,4-beta-cellobiosidase activity
AYN53_RS00540	COG5301	cellulose 1,4-beta-cellobiosidase activity
AYN53_RS00545	COG0727	PFAM Uncharacterised protein family (UPF0153)
AYN53_RS00565	COG2823	Periplasmic or secreted lipoprotein
AYN53_RS00575	COG4667	esterase of the alpha-beta hydrolase superfamily
AYN53_RS00580	COG0084	hydrolase, TatD family'
AYN53_RS00585	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AYN53_RS00615	COG0095	Lipoate-protein ligase
AYN53_RS00620	COG3726	membrane protein affecting hemolysin expression
AYN53_RS00625	COG0560	Phosphoserine phosphatase
AYN53_RS00630	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AYN53_RS00635	COG3172	ATPase kinase involved in NAD metabolism
AYN53_RS00635	COG1056	cytidyltransferase-related domain
AYN53_RS00640	COG0488	(ABC) transporter
AYN53_RS00645	COG0741	lytic transglycosylase activity
AYN53_RS00665	COG2207	Transcriptional regulator
AYN53_RS00665	COG3708	Transcriptional regulator
AYN53_RS00670	COG3045	CreA protein
AYN53_RS00675	COG0745	RESPONSE REGULATOR receiver
AYN53_RS00680	COG2205	protein histidine kinase activity
AYN53_RS00685	COG4452	Inner membrane protein CreD
AYN53_RS00690	COG0745	RESPONSE REGULATOR receiver
AYN53_RS00700	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AYN53_RS00710	COG0460	homoserine dehydrogenase
AYN53_RS00710	COG0527	aspartate kinase activity
AYN53_RS00720	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AYN53_RS00735	COG1115	amino acid carrier protein
AYN53_RS00745	COG0521	Mo-molybdopterin cofactor biosynthetic process
AYN53_RS00750	COG1584	GPR1 FUN34 yaaH family protein
AYN53_RS00775	COG3385	transposase activity
AYN53_RS00795	COG3119	arylsulfatase activity
AYN53_RS00805	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AYN53_RS00810	COG0583	DNA-binding transcription factor activity
AYN53_RS00830	COG0196	riboflavin kinase activity
AYN53_RS00845	COG1047	Peptidyl-prolyl cis-trans
AYN53_RS00875	COG0505	Belongs to the CarA family
AYN53_RS00880	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AYN53_RS00935	COG0644	oxidoreductase
AYN53_RS00940	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AYN53_RS00945	COG2271	Major facilitator Superfamily
AYN53_RS00960	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AYN53_RS00995	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AYN53_RS01005	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AYN53_RS01010	COG0564	pseudouridine synthase activity
AYN53_RS01025	COG0417	DNA replication proofreading
AYN53_RS01030	COG0235	Class ii aldolase
AYN53_RS01050	COG4977	sequence-specific DNA binding
AYN53_RS01055	COG0586	Pfam SNARE associated Golgi protein
AYN53_RS01065	COG1178	ABC-type Fe3 transport system permease component
AYN53_RS01070	COG4143	(ABC) transporter
AYN53_RS01110	COG0583	DNA-binding transcription factor activity
AYN53_RS01115	COG0028	Belongs to the TPP enzyme family
AYN53_RS01120	COG0440	acetolactate synthase activity
AYN53_RS01125	COG1609	Transcriptional regulator
AYN53_RS01145	COG3116	cell division
AYN53_RS01150	COG0768	penicillin binding
AYN53_RS01155	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AYN53_RS01160	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AYN53_RS01175	COG0772	Belongs to the SEDS family
AYN53_RS01190	COG1181	Belongs to the D-alanine--D-alanine ligase family
AYN53_RS01195	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AYN53_RS01200	COG0849	cell division
AYN53_RS01205	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AYN53_RS01225	COG0494	nUDIX hydrolase
AYN53_RS01240	COG0237	dephospho-CoA kinase activity
AYN53_RS01260	COG4969	Belongs to the N-Me-Phe pilin family
AYN53_RS01270	COG0157	Belongs to the NadC ModD family
AYN53_RS01275	COG3023	N-Acetylmuramoyl-L-alanine amidase
AYN53_RS01280	COG3725	Membrane protein required for beta-lactamase induction
AYN53_RS01285	COG1113	amino acid transport
AYN53_RS01290	COG2186	Transcriptional regulator
AYN53_RS01300	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AYN53_RS01305	COG0508	dehydrogenase complex catalyzes the overall conversion of
AYN53_RS01310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AYN53_RS01320	COG3064	Membrane
AYN53_RS01330	COG1049	propionate catabolic process, 2-methylcitrate cycle
AYN53_RS01365	COG2132	Multicopper oxidase
AYN53_RS01380	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AYN53_RS01385	COG0288	reversible hydration of carbon dioxide
AYN53_RS01390	COG1131	(ABC) transporter
AYN53_RS01395	COG0842	Transport permease protein
AYN53_RS01400	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN53_RS01405	COG0726	polysaccharide deacetylase
AYN53_RS01420	COG5464	transposase or invertase
AYN53_RS01425	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AYN53_RS01440	COG3539	Fimbrial protein
AYN53_RS01450	COG3539	Fimbrial protein
AYN53_RS01460	COG3121	Chaperone
AYN53_RS01465	COG3539	Fimbrial protein
AYN53_RS01470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AYN53_RS01475	COG0617	tRNA 3'-terminal CCA addition
AYN53_RS01485	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AYN53_RS01495	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AYN53_RS01500	COG1643	Atp-dependent helicase
AYN53_RS01505	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AYN53_RS01510	COG3853	Toxic anion resistance protein (TelA)
AYN53_RS01520	COG4774	siderophore transport
AYN53_RS01525	COG1120	ATPase activity
AYN53_RS01530	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AYN53_RS01535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AYN53_RS01555	COG2860	membrane
AYN53_RS01560	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AYN53_RS01575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AYN53_RS01580	COG3835	regulator
AYN53_RS01590	COG1408	metallophosphoesterase
AYN53_RS01605	COG0024	Methionine aminopeptidase
AYN53_RS01640	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AYN53_RS01645	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AYN53_RS01650	COG0575	Belongs to the CDS family
AYN53_RS01655	COG0750	zinc metalloprotease
AYN53_RS01665	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AYN53_RS01670	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AYN53_RS01695	COG0587	DNA-directed DNA polymerase activity
AYN53_RS01710	COG0346	lactoylglutathione lyase activity
AYN53_RS01715	COG0037	tRNA processing
AYN53_RS01720	COG4568	rho-dependent transcription termination
AYN53_RS01730	COG4681	YaeQ
AYN53_RS01735	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AYN53_RS01740	COG3015	lipoprotein NlpE involved in copper resistance
AYN53_RS01750	COG1720	tRNA m6t6A37 methyltransferase activity
AYN53_RS01760	COG1464	Belongs to the NlpA lipoprotein family
AYN53_RS01765	COG2011	ABC-type metal ion transport system permease component
AYN53_RS01775	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AYN53_RS01810	COG0656	L-ascorbic acid biosynthetic process
AYN53_RS01815	COG0583	DNA-binding transcription factor activity
AYN53_RS01825	COG1388	LysM domain
AYN53_RS01825	COG0741	lytic transglycosylase activity
AYN53_RS01830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AYN53_RS01835	COG2226	methyltransferase
AYN53_RS01845	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AYN53_RS01870	COG4104	PAAR repeat-containing protein
AYN53_RS01905	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AYN53_RS01915	COG1960	acyl-CoA dehydrogenase activity
AYN53_RS01925	COG0121	glutamine amidotransferase
AYN53_RS01930	COG3034	peptidoglycan biosynthetic process
AYN53_RS01935	COG0791	NLP P60 protein
AYN53_RS01940	COG1943	Transposase
AYN53_RS01960	COG2161	toxin-antitoxin pair type II binding
AYN53_RS01970	COG0454	-acetyltransferase
AYN53_RS01975	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AYN53_RS02010	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AYN53_RS02030	COG0582	viral genome integration into host DNA
AYN53_RS02195	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AYN53_RS02235	COG3646	Phage regulatory protein
AYN53_RS02245	COG4220	transposase activity
AYN53_RS02265	COG1030	water channel activity
AYN53_RS02315	COG1196	nuclear chromosome segregation
AYN53_RS02345	COG5301	cellulose 1,4-beta-cellobiosidase activity
AYN53_RS02400	COG0500	methyltransferase
AYN53_RS02445	COG3059	membrane
AYN53_RS02455	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AYN53_RS02460	COG2207	Transcriptional regulator
AYN53_RS02465	COG1620	l-lactate permease
AYN53_RS02470	COG0247	lactate metabolic process
AYN53_RS02475	COG1139	Iron-sulfur cluster binding protein
AYN53_RS02480	COG1556	Lactate utilization protein
AYN53_RS02490	COG0667	Aldo Keto reductase
AYN53_RS02500	COG2771	luxR family
AYN53_RS02500	COG2200	EAL domain
AYN53_RS02505	COG0583	DNA-binding transcription factor activity
AYN53_RS02520	COG0666	response to abiotic stimulus
AYN53_RS02530	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AYN53_RS02535	COG1304	FMN binding
AYN53_RS02540	COG0549	Belongs to the carbamate kinase family
AYN53_RS02545	COG0402	S-adenosylhomocysteine deaminase activity
AYN53_RS02550	COG1280	lysine exporter protein (LysE YggA)
AYN53_RS02565	COG3829	transcription factor binding
AYN53_RS02570	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AYN53_RS02575	COG0372	Belongs to the citrate synthase family
AYN53_RS02580	COG2079	MmgE PrpD family protein
AYN53_RS02585	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AYN53_RS02595	COG3122	Protein conserved in bacteria
AYN53_RS02615	COG4521	taurine ABC transporter
AYN53_RS02625	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AYN53_RS02630	COG2175	clavaminate synthase activity
AYN53_RS02635	COG0113	porphobilinogen synthase activity
AYN53_RS02640	COG3468	outer membrane autotransporter barrel domain protein
AYN53_RS02645	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AYN53_RS02650	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AYN53_RS02660	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AYN53_RS02685	COG1181	Belongs to the D-alanine--D-alanine ligase family
AYN53_RS02710	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AYN53_RS02725	COG4126	flavin adenine dinucleotide binding
AYN53_RS02745	COG1940	carbohydrate kinase activity
AYN53_RS02750	COG0419	ATPase involved in DNA repair
AYN53_RS02755	COG0420	3'-5' exonuclease activity
AYN53_RS02760	COG0745	RESPONSE REGULATOR receiver
AYN53_RS02765	COG5002	protein histidine kinase activity
AYN53_RS02770	COG1114	Component of the transport system for branched-chain amino acids
AYN53_RS02775	COG1113	amino acid transport
AYN53_RS02780	COG0366	Alpha amylase catalytic
AYN53_RS02800	COG1862	Preprotein translocase
AYN53_RS02805	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AYN53_RS02810	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AYN53_RS02815	COG1403	HNH endonuclease
AYN53_RS02820	COG3248	Nucleoside-binding outer membrane protein
AYN53_RS02825	COG4238	major outer membrane lipoprotein
AYN53_RS02835	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AYN53_RS02835	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AYN53_RS02850	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AYN53_RS02855	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AYN53_RS02870	COG0667	Aldo Keto reductase
AYN53_RS02885	COG0142	geranyltranstransferase activity
AYN53_RS02900	COG0693	protein deglycase activity
AYN53_RS02905	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AYN53_RS02915	COG2814	Major facilitator Superfamily
AYN53_RS02935	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AYN53_RS02940	COG1845	cytochrome c oxidase, subunit III
AYN53_RS02945	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AYN53_RS02950	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AYN53_RS02955	COG2223	nitrite transmembrane transporter activity
AYN53_RS02960	COG3056	Lipoprotein
AYN53_RS02970	COG0271	Belongs to the BolA IbaG family
AYN53_RS02995	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AYN53_RS03000	COG0776	regulation of translation
AYN53_RS03005	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AYN53_RS03010	COG1555	photosystem II stabilization
AYN53_RS03015	COG0824	Thioesterase
AYN53_RS03025	COG4533	DNA binding
AYN53_RS03035	COG1522	sequence-specific DNA binding
AYN53_RS03040	COG1132	(ABC) transporter
AYN53_RS03045	COG1132	(ABC) transporter
AYN53_RS03050	COG0347	Belongs to the P(II) protein family
AYN53_RS03060	COG1946	Acyl-CoA thioesterase
AYN53_RS03065	COG3126	Type III secretion system lipoprotein chaperone (YscW)
AYN53_RS03070	COG3695	enzyme binding
AYN53_RS03080	COG5507	3-demethylubiquinone-9 3-methyltransferase
AYN53_RS03085	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AYN53_RS03095	COG0110	maltose O-acetyltransferase activity
AYN53_RS03110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AYN53_RS03115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYN53_RS03120	COG1309	transcriptional regulator
AYN53_RS03125	COG1196	nuclear chromosome segregation
AYN53_RS03125	COG3264	Mechanosensitive ion channel
AYN53_RS03135	COG3923	Primosomal replication protein n
AYN53_RS03140	COG2832	Protein of unknown function (DUF454)
AYN53_RS03155	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AYN53_RS03195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AYN53_RS03205	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AYN53_RS03205	COG4651	solute:proton antiporter activity
AYN53_RS03210	COG2223	nitrite transmembrane transporter activity
AYN53_RS03215	COG0737	Belongs to the 5'-nucleotidase family
AYN53_RS03220	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AYN53_RS03230	COG3735	TraB family
AYN53_RS03240	COG2217	Heavy metal translocating P-type atpase
AYN53_RS03250	COG0531	amino acid
AYN53_RS03275	COG0789	Transcriptional regulator
AYN53_RS03285	COG1585	Membrane protein implicated in regulation of membrane protease activity
AYN53_RS03290	COG0330	HflC and HflK could
AYN53_RS03295	COG4619	ABC transporter
AYN53_RS03305	COG3118	belongs to the thioredoxin family
AYN53_RS03310	COG0300	oxidoreductase activity
AYN53_RS03315	COG2755	lipolytic protein G-D-S-L family
AYN53_RS03320	COG4181	ATPase activity
AYN53_RS03325	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AYN53_RS03335	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AYN53_RS03340	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AYN53_RS03360	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AYN53_RS03375	COG2501	S4 domain
AYN53_RS03385	COG3539	Fimbrial protein
AYN53_RS03390	COG3121	Chaperone
AYN53_RS03395	COG3188	usher protein
AYN53_RS03400	COG3539	Fimbrial protein
AYN53_RS03405	COG3539	Fimbrial protein
AYN53_RS03410	COG2197	response regulator
AYN53_RS03420	COG0582	viral genome integration into host DNA
AYN53_RS03510	COG2076	Multidrug Resistance protein
AYN53_RS03515	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AYN53_RS03520	COG1881	PFAM PEBP family protein
AYN53_RS03525	COG2207	Transcriptional regulator
AYN53_RS03570	COG3272	Protein of unknown function (DUF1722)
AYN53_RS03580	COG2207	Transcriptional regulator
AYN53_RS03620	COG4571	Outer membrane protease
AYN53_RS03635	COG2207	Transcriptional regulator
AYN53_RS03645	COG4783	chaperone-mediated protein folding
AYN53_RS03650	COG1215	transferase activity, transferring glycosyl groups
AYN53_RS03675	COG5002	protein histidine kinase activity
AYN53_RS03680	COG0745	RESPONSE REGULATOR receiver
AYN53_RS03690	COG1538	Outer membrane efflux protein
AYN53_RS03695	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYN53_RS03700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYN53_RS03705	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AYN53_RS03710	COG1113	amino acid transport
AYN53_RS03715	COG0668	transmembrane transport
AYN53_RS03720	COG0778	Nitroreductase
AYN53_RS03725	COG2315	Protein conserved in bacteria
AYN53_RS03765	COG2977	Belongs to the P-Pant transferase superfamily
AYN53_RS03770	COG4771	TonB-dependent receptor
AYN53_RS03780	COG2382	esterase
AYN53_RS03785	COG3251	PFAM MbtH domain protein
AYN53_RS03790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AYN53_RS03790	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AYN53_RS03795	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
AYN53_RS03800	COG1120	ATPase activity
AYN53_RS03805	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AYN53_RS03810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AYN53_RS03820	COG4592	Periplasmic binding protein
AYN53_RS03825	COG1169	isochorismate synthase
AYN53_RS03830	COG1021	2,3-dihydroxybenzoate-AMP ligase
AYN53_RS03835	COG1535	isochorismatase
AYN53_RS03835	COG3433	isochorismatase activity
AYN53_RS03840	COG1028	Short-chain dehydrogenase reductase Sdr
AYN53_RS03845	COG2050	protein possibly involved in aromatic compounds catabolism
AYN53_RS03850	COG1966	Carbon starvation protein
AYN53_RS03855	COG2879	small protein
AYN53_RS03860	COG0371	Dehydrogenase
AYN53_RS03865	COG0436	Aminotransferase
AYN53_RS03870	COG1475	DNA binding
AYN53_RS03880	COG0583	DNA-binding transcription factor activity
AYN53_RS03885	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AYN53_RS03890	COG0450	alkyl hydroperoxide reductase
AYN53_RS03895	COG3634	alkyl hydroperoxide reductase activity
AYN53_RS03900	COG0589	response to stress
AYN53_RS03905	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AYN53_RS03915	COG3719	Belongs to the RNase T2 family
AYN53_RS03920	COG0471	metal ion transport
AYN53_RS03935	COG3051	citrate lyase alpha subunit
AYN53_RS03940	COG2301	Belongs to the HpcH HpaI aldolase family
AYN53_RS03950	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
AYN53_RS03955	COG3290	protein histidine kinase activity
AYN53_RS03960	COG4565	transcriptional regulatory protein
AYN53_RS03965	COG3069	C4-dicarboxylate transmembrane transporter activity
AYN53_RS03985	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AYN53_RS03990	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AYN53_RS04005	COG0583	DNA-binding transcription factor activity
AYN53_RS04020	COG1686	Belongs to the peptidase S11 family
AYN53_RS04025	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AYN53_RS04030	COG0772	Belongs to the SEDS family
AYN53_RS04035	COG0768	penicillin binding
AYN53_RS04045	COG0799	negative regulation of ribosome biogenesis
AYN53_RS04050	COG0406	alpha-ribazole phosphatase activity
AYN53_RS04060	COG1466	dna polymerase III delta subunit
AYN53_RS04075	COG2888	peptidyl-tyrosine sulfation
AYN53_RS04085	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AYN53_RS04095	COG2214	Heat shock protein DnaJ domain protein
AYN53_RS04100	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AYN53_RS04110	COG2214	Heat shock protein DnaJ domain protein
AYN53_RS04115	COG0443	Heat shock 70 kDa protein
AYN53_RS04125	COG1126	abc transporter atp-binding protein
AYN53_RS04130	COG0765	amino acid transport
AYN53_RS04135	COG0765	amino acid transport
AYN53_RS04140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AYN53_RS04150	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AYN53_RS04155	COG4535	Mg2 and Co2 transporter CorC
AYN53_RS04165	COG1702	phosphate starvation-inducible protein PhoH
AYN53_RS04175	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AYN53_RS04215	COG0367	asparagine synthase
AYN53_RS04220	COG0647	UMP catabolic process
AYN53_RS04225	COG1940	carbohydrate kinase activity
AYN53_RS04225	COG1846	Transcriptional regulator
AYN53_RS04230	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AYN53_RS04240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AYN53_RS04240	COG2190	(PTS) system
AYN53_RS04240	COG1263	PTS System
AYN53_RS04260	COG0735	belongs to the Fur family
AYN53_RS04270	COG0716	FMN binding
AYN53_RS04280	COG0596	Alpha beta hydrolase
AYN53_RS04285	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AYN53_RS04290	COG0033	Phosphoglucomutase
AYN53_RS04295	COG0531	amino acid
AYN53_RS04300	COG1982	Orn Lys Arg decarboxylase major
AYN53_RS04315	COG0745	RESPONSE REGULATOR receiver
AYN53_RS04320	COG2205	protein histidine kinase activity
AYN53_RS04375	COG3272	Protein of unknown function (DUF1722)
AYN53_RS04380	COG0415	Belongs to the DNA photolyase family
AYN53_RS04390	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AYN53_RS04395	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AYN53_RS04400	COG1984	allophanate hydrolase subunit 2
AYN53_RS04415	COG3180	Ammonia monooxygenase
AYN53_RS04420	COG2186	Transcriptional regulator
AYN53_RS04425	COG0473	3-isopropylmalate dehydrogenase activity
AYN53_RS04425	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AYN53_RS04430	COG1063	alcohol dehydrogenase
AYN53_RS04435	COG1028	Short-chain dehydrogenase reductase Sdr
AYN53_RS04445	COG2721	sulfolactate sulfo-lyase activity
AYN53_RS04450	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AYN53_RS04460	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AYN53_RS04465	COG3539	Fimbrial protein
AYN53_RS04470	COG3121	Chaperone
AYN53_RS04480	COG3539	Fimbrial protein
AYN53_RS04485	COG0372	Belongs to the citrate synthase family
AYN53_RS04495	COG2009	succinate dehydrogenase
AYN53_RS04500	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AYN53_RS04505	COG1053	succinate dehydrogenase
AYN53_RS04510	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AYN53_RS04515	COG0567	Dehydrogenase, E1 component
AYN53_RS04520	COG0508	dehydrogenase complex catalyzes the overall conversion of
AYN53_RS04530	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AYN53_RS04545	COG1271	oxidase subunit
AYN53_RS04550	COG1294	oxidase, subunit
AYN53_RS04555	COG4890	Cyd operon protein YbgT
AYN53_RS04560	COG3790	cyd operon protein YbgE
AYN53_RS04565	COG0824	Thioesterase
AYN53_RS04570	COG0811	peptide transport
AYN53_RS04575	COG0848	biopolymer transport protein
AYN53_RS04580	COG3064	Membrane
AYN53_RS04590	COG2885	chlorophyll binding
AYN53_RS04595	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AYN53_RS04655	COG3201	nicotinamide mononucleotide transporter
AYN53_RS04665	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AYN53_RS04675	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AYN53_RS04705	COG2017	converts alpha-aldose to the beta-anomer
AYN53_RS04715	COG1085	galactose-1-phosphate uridylyltransferase
AYN53_RS04720	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AYN53_RS04725	COG1119	ATPase activity
AYN53_RS04730	COG3585	molybdate ion transport
AYN53_RS04730	COG2005	Transcriptional regulator
AYN53_RS04745	COG0725	ABC transporter, periplasmic molybdate-binding protein
AYN53_RS04750	COG4149	molybdate abc transporter
AYN53_RS04760	COG0561	phosphatase activity
AYN53_RS04770	COG0583	DNA-binding transcription factor activity
AYN53_RS04775	COG2828	Protein conserved in bacteria
AYN53_RS04780	COG0471	metal ion transport
AYN53_RS04785	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AYN53_RS04790	COG4677	pectinesterase activity
AYN53_RS04800	COG2267	carboxylic ester hydrolase activity
AYN53_RS04820	COG1881	PFAM PEBP family protein
AYN53_RS04825	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AYN53_RS04840	COG2226	methyltransferase
AYN53_RS04845	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AYN53_RS04855	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AYN53_RS04865	COG0521	Mo-molybdopterin cofactor biosynthetic process
AYN53_RS04875	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AYN53_RS04880	COG0314	molybdopterin synthase activity
AYN53_RS04885	COG0670	Belongs to the BI1 family
AYN53_RS04915	COG0842	Transport permease protein
AYN53_RS04920	COG0842	Transport permease protein
AYN53_RS04925	COG1131	(ABC) transporter
AYN53_RS04935	COG1309	transcriptional regulator
AYN53_RS04940	COG0513	Belongs to the DEAD box helicase family
AYN53_RS04950	COG1199	ATP-dependent helicase activity
AYN53_RS04955	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AYN53_RS04960	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AYN53_RS04970	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AYN53_RS04985	COG1126	abc transporter atp-binding protein
AYN53_RS04990	COG0765	amino acid transport
AYN53_RS04995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AYN53_RS05005	COG5006	permease, DMT superfamily
AYN53_RS05010	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AYN53_RS05015	COG2194	sulfuric ester hydrolase activity
AYN53_RS05025	COG1321	iron dependent repressor
AYN53_RS05030	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AYN53_RS05035	COG1376	ErfK ybiS ycfS ynhG family protein
AYN53_RS05040	COG0488	(ABC) transporter
AYN53_RS05045	COG0561	phosphatase activity
AYN53_RS05050	COG1882	Formate acetyltransferase
AYN53_RS05055	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AYN53_RS05060	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AYN53_RS05065	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AYN53_RS05070	COG0303	'Molybdopterin
AYN53_RS05075	COG1446	asparaginase
AYN53_RS05085	COG0747	negative chemotaxis
AYN53_RS05100	COG2200	EAL domain
AYN53_RS05105	COG2199	diguanylate cyclase activity
AYN53_RS05110	COG1413	lyase activity
AYN53_RS05135	COG0625	glutathione transferase activity
AYN53_RS05140	COG1686	Belongs to the peptidase S11 family
AYN53_RS05145	COG1349	DNA-binding transcription factor activity
AYN53_RS05150	COG0671	phosphoesterase, PA-phosphatase related
AYN53_RS05155	COG2814	Major facilitator Superfamily
AYN53_RS05165	COG0561	phosphatase activity
AYN53_RS05170	COG0738	Major facilitator superfamily
AYN53_RS05175	COG3226	Transcriptional regulator
AYN53_RS05180	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AYN53_RS05225	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AYN53_RS05255	COG4695	Portal protein
AYN53_RS05370	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AYN53_RS05430	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AYN53_RS05440	COG0778	Nitroreductase
AYN53_RS05460	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AYN53_RS05465	COG3842	ATPase activity
AYN53_RS05470	COG1176	ABC-type spermidine putrescine transport system, permease component I
AYN53_RS05475	COG1177	transmembrane transport
AYN53_RS05490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AYN53_RS05495	COG4160	amino acid transport
AYN53_RS05500	COG4215	(ABC) transporter
AYN53_RS05505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AYN53_RS05510	COG1126	abc transporter atp-binding protein
AYN53_RS05525	COG3023	N-Acetylmuramoyl-L-alanine amidase
AYN53_RS05530	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AYN53_RS05535	COG0702	epimerase
AYN53_RS05540	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AYN53_RS05545	COG0028	Belongs to the TPP enzyme family
AYN53_RS05550	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AYN53_RS05560	COG2431	L-lysine efflux transmembrane transporter activity
AYN53_RS05575	COG3593	DNA synthesis involved in DNA repair
AYN53_RS05580	COG2990	Protein conserved in bacteria
AYN53_RS05585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYN53_RS05595	COG1278	Cold shock
AYN53_RS05605	COG0542	response to heat
AYN53_RS05625	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AYN53_RS05630	COG4988	ABC transporter
AYN53_RS05635	COG0492	ferredoxin-NADP+ reductase activity
AYN53_RS05645	COG1522	sequence-specific DNA binding
AYN53_RS05650	COG1178	ABC-type Fe3 transport system permease component
AYN53_RS05650	COG1674	ftsk spoiiie
AYN53_RS05660	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AYN53_RS05670	COG0243	molybdopterin cofactor binding
AYN53_RS05675	COG0437	4 iron, 4 sulfur cluster binding
AYN53_RS05680	COG3302	dmso reductase anchor subunit
AYN53_RS05685	COG1335	isochorismatase
AYN53_RS05695	COG0531	amino acid
AYN53_RS05705	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AYN53_RS05710	COG1882	Formate acetyltransferase
AYN53_RS05715	COG2116	formate transmembrane transporter activity
AYN53_RS05720	COG1944	ATP diphosphatase activity
AYN53_RS05740	COG0539	negative regulation of cytoplasmic translation
AYN53_RS05750	COG0658	competence protein
AYN53_RS05750	COG2333	competence protein COMEC
AYN53_RS05765	COG3214	Protein conserved in bacteria
AYN53_RS05780	COG3173	Aminoglycoside phosphotransferase
AYN53_RS05785	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AYN53_RS05790	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AYN53_RS05800	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
AYN53_RS05810	COG2989	Protein conserved in bacteria
AYN53_RS05820	COG3108	Peptidase M15
AYN53_RS05825	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AYN53_RS05830	COG1448	Aminotransferase
AYN53_RS05850	COG0308	aminopeptidase N
AYN53_RS05875	COG0488	(ABC) transporter
AYN53_RS05880	COG2995	paraquat-inducible protein a
AYN53_RS05885	COG3008	intermembrane lipid transfer
AYN53_RS05885	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AYN53_RS05890	COG3009	Protein conserved in bacteria
AYN53_RS05895	COG3130	regulation of translation
AYN53_RS05905	COG1067	ATP-dependent peptidase activity
AYN53_RS05930	COG3070	regulator of competence-specific genes
AYN53_RS05935	COG1289	transmembrane transporter activity
AYN53_RS05940	COG3304	Inner membrane component domain
AYN53_RS05945	COG0210	DNA helicase
AYN53_RS05960	COG1832	CoA-binding protein
AYN53_RS05975	COG1254	Belongs to the acylphosphatase family
AYN53_RS05980	COG2920	part of a sulfur-relay system
AYN53_RS05985	COG0670	Belongs to the BI1 family
AYN53_RS05995	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AYN53_RS06000	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AYN53_RS06005	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
AYN53_RS06010	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AYN53_RS06015	COG1999	signal sequence binding
AYN53_RS06020	COG1773	rubredoxin
AYN53_RS06025	COG1271	oxidase subunit
AYN53_RS06030	COG1294	oxidase, subunit
AYN53_RS06045	COG0489	protein tyrosine kinase activity
AYN53_RS06045	COG3206	protein involved in exopolysaccharide biosynthesis
AYN53_RS06050	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AYN53_RS06055	COG1596	polysaccharide export
AYN53_RS06060	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AYN53_RS06080	COG1278	Cold shock
AYN53_RS06085	COG1278	Cold shock
AYN53_RS06105	COG0348	domain, Protein
AYN53_RS06110	COG2198	Histidine kinase
AYN53_RS06110	COG2205	protein histidine kinase activity
AYN53_RS06110	COG0784	Response regulator, receiver
AYN53_RS06115	COG0745	RESPONSE REGULATOR receiver
AYN53_RS06120	COG3005	denitrification pathway
AYN53_RS06130	COG3381	protein complex oligomerization
AYN53_RS06170	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AYN53_RS06225	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AYN53_RS06235	COG3729	General stress protein
AYN53_RS06240	COG1309	transcriptional regulator
AYN53_RS06245	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AYN53_RS06245	COG0506	proline dehydrogenase activity
AYN53_RS06245	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AYN53_RS06255	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AYN53_RS06280	COG1702	phosphate starvation-inducible protein PhoH
AYN53_RS06305	COG3381	protein complex oligomerization
AYN53_RS06315	COG1462	curli production assembly transport component CsgG
AYN53_RS06330	COG2197	response regulator
AYN53_RS06360	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AYN53_RS06365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AYN53_RS06390	COG2943	transferase activity, transferring hexosyl groups
AYN53_RS06395	COG5645	(Lipo)protein
AYN53_RS06470	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AYN53_RS06480	COG1560	Kdo2-lipid A biosynthetic process
AYN53_RS06525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AYN53_RS06535	COG0673	inositol 2-dehydrogenase activity
AYN53_RS06540	COG0728	peptidoglycan biosynthetic process
AYN53_RS06545	COG3418	PFAM FlgN family protein
AYN53_RS06550	COG2747	anti-sigma28 factor FlgM
AYN53_RS06555	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
AYN53_RS06560	COG1815	bacterial-type flagellum-dependent cell motility
AYN53_RS06565	COG1558	bacterial-type flagellum-dependent cell motility
AYN53_RS06570	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AYN53_RS06575	COG1749	Flagellar hook protein flgE
AYN53_RS06580	COG4787	bacterial-type flagellum-dependent cell motility
AYN53_RS06585	COG4786	Flagellar basal body rod
AYN53_RS06600	COG3951	Flagellar rod assembly protein muramidase FlgJ
AYN53_RS06600	COG1705	Flagellar rod assembly protein muramidase FlgJ
AYN53_RS06605	COG1256	bacterial-type flagellum assembly
AYN53_RS06610	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AYN53_RS06615	COG1530	ribonuclease E activity
AYN53_RS06625	COG0564	pseudouridine synthase activity
AYN53_RS06630	COG0424	maF-like protein
AYN53_RS06635	COG1399	metal-binding, possibly nucleic acid-binding protein
AYN53_RS06655	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AYN53_RS06660	COG1028	Short-chain dehydrogenase reductase Sdr
AYN53_RS06670	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AYN53_RS06675	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AYN53_RS06680	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AYN53_RS06690	COG0470	DNA polymerase III
AYN53_RS06695	COG0084	hydrolase, TatD family'
AYN53_RS06700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AYN53_RS06700	COG1263	PTS System
AYN53_RS06705	COG0537	adenosine 5'-monophosphoramidase activity
AYN53_RS06710	COG5633	Lipoprotein
AYN53_RS06715	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
AYN53_RS06735	COG1252	NADH dehydrogenase
AYN53_RS06740	COG3134	Outer membrane lipoprotein
AYN53_RS06745	COG1309	transcriptional regulator
AYN53_RS06755	COG1388	LysM domain
AYN53_RS06755	COG1376	ErfK ybiS ycfS ynhG family protein
AYN53_RS06760	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AYN53_RS06765	COG4591	ABC-type transport system involved in lipoprotein release permease component
AYN53_RS06775	COG4591	ABC-type transport system involved in lipoprotein release permease component
AYN53_RS06785	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AYN53_RS06790	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AYN53_RS06800	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AYN53_RS06805	COG1177	transmembrane transport
AYN53_RS06815	COG3842	ATPase activity
AYN53_RS06830	COG2850	peptidyl-arginine hydroxylation
AYN53_RS06835	COG2205	protein histidine kinase activity
AYN53_RS06845	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AYN53_RS06865	COG1187	pseudouridine synthase activity
AYN53_RS06870	COG0538	isocitrate dehydrogenase activity
AYN53_RS06875	COG1073	alpha beta
AYN53_RS06880	COG0583	DNA-binding transcription factor activity
AYN53_RS06915	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AYN53_RS06920	COG4571	Outer membrane protease
AYN53_RS06950	COG3468	outer membrane autotransporter barrel domain protein
AYN53_RS06955	COG3468	outer membrane autotransporter barrel domain protein
AYN53_RS06970	COG2894	cell division
AYN53_RS06985	COG0179	Fumarylacetoacetate (FAA) hydrolase
AYN53_RS07010	COG3477	response to acidic pH
AYN53_RS07015	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AYN53_RS07030	COG2719	SpoVR family
AYN53_RS07040	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AYN53_RS07050	COG1619	proteins homologs of microcin C7 resistance protein MccF
AYN53_RS07060	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
AYN53_RS07075	COG0157	Belongs to the NadC ModD family
AYN53_RS07080	COG0500	methyltransferase
AYN53_RS07085	COG1120	ATPase activity
AYN53_RS07090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AYN53_RS07095	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AYN53_RS07130	COG0012	GTP binding
AYN53_RS07145	COG0659	secondary active sulfate transmembrane transporter activity
AYN53_RS07155	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AYN53_RS07185	COG2890	protein-(glutamine-N5) methyltransferase activity
AYN53_RS07190	COG3094	Invasion gene expression up-regulator, SirB
AYN53_RS07195	COG2912	Transglutaminase-like superfamily
AYN53_RS07215	COG0737	Belongs to the 5'-nucleotidase family
AYN53_RS07225	COG0737	Belongs to the 5'-nucleotidase family
AYN53_RS07230	COG0641	radical SAM
AYN53_RS07235	COG0387	Pfam Sodium calcium exchanger
AYN53_RS07245	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AYN53_RS07250	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AYN53_RS07255	COG2197	response regulator
AYN53_RS07260	COG3850	Histidine kinase
AYN53_RS07270	COG2223	nitrite transmembrane transporter activity
AYN53_RS07275	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AYN53_RS07280	COG1140	nitrate reductase beta subunit
AYN53_RS07285	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AYN53_RS07290	COG2181	nitrate reductase activity
AYN53_RS07295	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AYN53_RS07340	COG0788	formyltetrahydrofolate deformylase activity
AYN53_RS07350	COG1752	Esterase of the alpha-beta hydrolase superfamily
AYN53_RS07355	COG0745	RESPONSE REGULATOR receiver
AYN53_RS07360	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AYN53_RS07370	COG1435	thymidine kinase activity
AYN53_RS07375	COG1012	belongs to the aldehyde dehydrogenase family
AYN53_RS07375	COG1454	alcohol dehydrogenase
AYN53_RS07380	COG2095	MarC family integral membrane protein
AYN53_RS07385	COG4166	transmembrane transport
AYN53_RS07390	COG0601	transmembrane transport
AYN53_RS07395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AYN53_RS07400	COG0444	Belongs to the ABC transporter superfamily
AYN53_RS07405	COG4608	Belongs to the ABC transporter superfamily
AYN53_RS07410	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AYN53_RS07430	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AYN53_RS07435	COG2350	Protein conserved in bacteria
AYN53_RS07440	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AYN53_RS07450	COG1607	acyl-coa hydrolase
AYN53_RS07465	COG0727	PFAM Uncharacterised protein family (UPF0153)
AYN53_RS07470	COG3047	cAMP biosynthetic process
AYN53_RS07475	COG0582	viral genome integration into host DNA
AYN53_RS07485	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AYN53_RS07530	COG1846	Transcriptional regulator
AYN53_RS07535	COG1484	DNA-dependent DNA replication
AYN53_RS07540	COG1846	Transcriptional regulator
AYN53_RS07580	COG1403	HNH endonuclease
AYN53_RS07585	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
AYN53_RS07590	COG0484	heat shock protein binding
AYN53_RS07615	COG3772	lysozyme
AYN53_RS07650	COG0740	serine-type endopeptidase activity
AYN53_RS07730	COG5301	cellulose 1,4-beta-cellobiosidase activity
AYN53_RS07770	COG0727	PFAM Uncharacterised protein family (UPF0153)
AYN53_RS07800	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AYN53_RS07800	COG0512	Glutamine amidotransferase of anthranilate synthase
AYN53_RS07805	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AYN53_RS07815	COG0613	PHP domain protein
AYN53_RS07820	COG0009	L-threonylcarbamoyladenylate synthase
AYN53_RS07825	COG1187	pseudouridine synthase activity
AYN53_RS07840	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
AYN53_RS07845	COG1028	Short-chain dehydrogenase reductase Sdr
AYN53_RS07850	COG0616	signal peptide processing
AYN53_RS07860	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AYN53_RS07870	COG0583	DNA-binding transcription factor activity
AYN53_RS07880	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AYN53_RS07890	COG0671	phosphoesterase, PA-phosphatase related
AYN53_RS07895	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AYN53_RS07900	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AYN53_RS07910	COG0023	Translation Initiation Factor
AYN53_RS07920	COG1349	DNA-binding transcription factor activity
AYN53_RS07930	COG5001	Diguanylate cyclase
AYN53_RS07945	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AYN53_RS07945	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AYN53_RS07950	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AYN53_RS07960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYN53_RS07975	COG2814	Major facilitator Superfamily
AYN53_RS07980	COG4172	Belongs to the ABC transporter superfamily
AYN53_RS07985	COG4172	Belongs to the ABC transporter superfamily
AYN53_RS07990	COG4171	peptide transport system, permease
AYN53_RS08000	COG2076	Multidrug Resistance protein
AYN53_RS08005	COG1881	PFAM PEBP family protein
AYN53_RS08010	COG2207	Transcriptional regulator
AYN53_RS08020	COG1073	alpha beta
AYN53_RS08025	COG0583	DNA-binding transcription factor activity
AYN53_RS08030	COG4168	peptide transport system, permease
AYN53_RS08035	COG4166	transmembrane transport
AYN53_RS08045	COG0531	amino acid
AYN53_RS08050	COG0174	glutamine synthetase
AYN53_RS08055	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AYN53_RS08060	COG1917	Cupin 2, conserved barrel domain protein
AYN53_RS08060	COG1396	sequence-specific DNA binding
AYN53_RS08065	COG1012	belongs to the aldehyde dehydrogenase family
AYN53_RS08070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AYN53_RS08075	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AYN53_RS08080	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AYN53_RS08085	COG1842	Phage shock protein A
AYN53_RS08095	COG1983	PspC domain protein
AYN53_RS08105	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AYN53_RS08110	COG3106	COG3106 Predicted ATPase
AYN53_RS08120	COG3283	Transcriptional regulator of aromatic amino acids metabolism
AYN53_RS08125	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AYN53_RS08130	COG4948	Mandelate Racemase Muconate Lactonizing
AYN53_RS08135	COG2866	Carboxypeptidase
AYN53_RS08140	COG4166	transmembrane transport
AYN53_RS08145	COG0668	transmembrane transport
AYN53_RS08150	COG3182	Iron-regulated membrane protein
AYN53_RS08155	COG0589	response to stress
AYN53_RS08160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AYN53_RS08165	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AYN53_RS08175	COG2840	Smr protein MutS2
AYN53_RS08180	COG3706	GGDEF domain
AYN53_RS08195	COG0513	Belongs to the DEAD box helicase family
AYN53_RS08205	COG0582	viral genome integration into host DNA
AYN53_RS08295	COG3756	Protein conserved in bacteria
AYN53_RS08300	COG1484	DNA-dependent DNA replication
AYN53_RS08305	COG1846	Transcriptional regulator
AYN53_RS08390	COG0589	response to stress
AYN53_RS08395	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AYN53_RS08400	COG1013	pyruvate-flavodoxin oxidoreductase activity
AYN53_RS08400	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AYN53_RS08400	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AYN53_RS08400	COG0674	pyruvate-flavodoxin oxidoreductase activity
AYN53_RS08405	COG3042	response to heat
AYN53_RS08410	COG3187	Heat shock protein
AYN53_RS08415	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AYN53_RS08430	COG2911	Protein conserved in bacteria
AYN53_RS08440	COG3784	Protein of unknown function (DUF1318)
AYN53_RS08445	COG0667	Aldo Keto reductase
AYN53_RS08460	COG1643	Atp-dependent helicase
AYN53_RS08485	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AYN53_RS08490	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AYN53_RS08495	COG3038	cytochrome b561
AYN53_RS08500	COG0583	DNA-binding transcription factor activity
AYN53_RS08505	COG5383	Protein conserved in bacteria
AYN53_RS08525	COG2841	Protein conserved in bacteria
AYN53_RS08530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AYN53_RS08535	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AYN53_RS08540	COG1275	C4-dicarboxylate transporter malic acid transport protein
AYN53_RS08545	COG0500	methyltransferase
AYN53_RS08555	COG0826	peptidase U32
AYN53_RS08565	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AYN53_RS08570	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AYN53_RS08575	COG3842	ATPase activity
AYN53_RS08580	COG1176	ABC-type spermidine putrescine transport system, permease component I
AYN53_RS08585	COG1177	transmembrane transport
AYN53_RS08595	COG1388	LysM domain
AYN53_RS08595	COG1470	cell adhesion involved in biofilm formation
AYN53_RS08615	COG3238	Protein conserved in bacteria
AYN53_RS08620	COG1247	-acetyltransferase
AYN53_RS08625	COG2130	NADP-dependent
AYN53_RS08640	COG1113	amino acid transport
AYN53_RS08660	COG3209	COG3209 Rhs family protein
AYN53_RS08695	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AYN53_RS08705	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AYN53_RS08710	COG0384	phenazine biosynthesis protein PhzF
AYN53_RS08720	COG2181	nitrate reductase activity
AYN53_RS08725	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AYN53_RS08730	COG1140	nitrate reductase beta subunit
AYN53_RS08735	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AYN53_RS08740	COG2223	nitrite transmembrane transporter activity
AYN53_RS08750	COG0697	spore germination
AYN53_RS08755	COG0243	molybdopterin cofactor binding
AYN53_RS08755	COG3383	formate dehydrogenase (NAD+) activity
AYN53_RS08760	COG3383	formate dehydrogenase (NAD+) activity
AYN53_RS08760	COG0243	molybdopterin cofactor binding
AYN53_RS08765	COG0437	4 iron, 4 sulfur cluster binding
AYN53_RS08770	COG2864	formate dehydrogenase
AYN53_RS08775	COG3093	addiction module antidote protein HigA
AYN53_RS08785	COG1064	alcohol dehydrogenase
AYN53_RS08805	COG1764	response to oxidative stress
AYN53_RS08810	COG2200	EAL domain
AYN53_RS08810	COG2199	diguanylate cyclase activity
AYN53_RS08810	COG2202	Pas domain
AYN53_RS08820	COG1649	PFAM Uncharacterised BCR, COG1649
AYN53_RS08825	COG0531	amino acid
AYN53_RS08850	COG3781	membrane
AYN53_RS08860	COG2199	diguanylate cyclase activity
AYN53_RS08870	COG2066	Belongs to the glutaminase family
AYN53_RS08880	COG0583	DNA-binding transcription factor activity
AYN53_RS08900	COG1846	Transcriptional regulator
AYN53_RS08905	COG4977	sequence-specific DNA binding
AYN53_RS08915	COG2723	6-phospho-beta-galactosidase activity
AYN53_RS08925	COG1447	Phosphotransferase system cellobiose-specific component IIA
AYN53_RS08930	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AYN53_RS08940	COG2188	Transcriptional regulator
AYN53_RS08945	COG0697	spore germination
AYN53_RS08950	COG2814	Major facilitator Superfamily
AYN53_RS08960	COG3706	GGDEF domain
AYN53_RS08965	COG0339	signal peptide processing
AYN53_RS08975	COG4221	oxidoreductase activity
AYN53_RS08980	COG1802	Transcriptional regulator
AYN53_RS08990	COG0246	Mannitol dehydrogenase
AYN53_RS08995	COG0477	Major facilitator Superfamily
AYN53_RS09000	COG1063	alcohol dehydrogenase
AYN53_RS09005	COG4948	Mandelate Racemase Muconate Lactonizing
AYN53_RS09020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AYN53_RS09035	COG0243	molybdopterin cofactor binding
AYN53_RS09040	COG0243	molybdopterin cofactor binding
AYN53_RS09045	COG0437	4 iron, 4 sulfur cluster binding
AYN53_RS09050	COG3302	dmso reductase anchor subunit
AYN53_RS09055	COG3381	protein complex oligomerization
AYN53_RS09065	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AYN53_RS09070	COG1940	carbohydrate kinase activity
AYN53_RS09075	COG0583	DNA-binding transcription factor activity
AYN53_RS09080	COG2814	Major facilitator Superfamily
AYN53_RS09095	COG3591	Belongs to the peptidase S1B family
AYN53_RS09110	COG0628	permease
AYN53_RS09115	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AYN53_RS09120	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AYN53_RS09135	COG0531	amino acid
AYN53_RS09145	COG3136	membrane protein required for alginate biosynthesis
AYN53_RS09150	COG0745	RESPONSE REGULATOR receiver
AYN53_RS09155	COG2205	protein histidine kinase activity
AYN53_RS09165	COG0114	fumarate hydratase activity
AYN53_RS09170	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AYN53_RS09170	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AYN53_RS09175	COG1482	cell wall glycoprotein biosynthetic process
AYN53_RS09180	COG5339	Protein conserved in bacteria
AYN53_RS09185	COG1028	Short-chain dehydrogenase reductase Sdr
AYN53_RS09190	COG1609	Transcriptional regulator
AYN53_RS09195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AYN53_RS09195	COG1263	PTS System
AYN53_RS09200	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AYN53_RS09210	COG0673	inositol 2-dehydrogenase activity
AYN53_RS09255	COG4659	FMN binding
AYN53_RS09260	COG4660	Part of a membrane complex involved in electron transport
AYN53_RS09265	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AYN53_RS09275	COG3104	oligopeptide transport
AYN53_RS09280	COG0625	glutathione transferase activity
AYN53_RS09285	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AYN53_RS09300	COG3895	Periplasmic Protein
AYN53_RS09310	COG3133	Outer membrane lipoprotein
AYN53_RS09325	COG1566	PFAM secretion protein HlyD family protein
AYN53_RS09330	COG1289	transmembrane transporter activity
AYN53_RS09335	COG4989	oxidoreductase activity
AYN53_RS09340	COG3313	Fe-S protein
AYN53_RS09350	COG1309	transcriptional regulator
AYN53_RS09360	COG0346	lactoylglutathione lyase activity
AYN53_RS09375	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AYN53_RS09380	COG0791	NLP P60 protein
AYN53_RS09385	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AYN53_RS09405	COG0583	DNA-binding transcription factor activity
AYN53_RS09410	COG2814	Major facilitator Superfamily
AYN53_RS09415	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AYN53_RS09420	COG0307	riboflavin synthase, alpha
AYN53_RS09430	COG3468	outer membrane autotransporter barrel domain protein
AYN53_RS09455	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
AYN53_RS09460	COG0437	4 iron, 4 sulfur cluster binding
AYN53_RS09470	COG2414	aldehyde ferredoxin oxidoreductase
AYN53_RS09475	COG0437	4 iron, 4 sulfur cluster binding
AYN53_RS09485	COG0469	pyruvate kinase activity
AYN53_RS09490	COG4238	major outer membrane lipoprotein
AYN53_RS09495	COG1376	ErfK ybiS ycfS ynhG family protein
AYN53_RS09515	COG0719	Fe-S assembly protein
AYN53_RS09520	COG0396	ATPase activity
AYN53_RS09525	COG0719	Fe-S assembly protein
AYN53_RS09530	COG0316	Belongs to the HesB IscA family
AYN53_RS09540	COG2050	protein possibly involved in aromatic compounds catabolism
AYN53_RS09545	COG0277	FAD linked oxidase domain protein
AYN53_RS09545	COG0247	lactate metabolic process
AYN53_RS09550	COG0628	permease
AYN53_RS09565	COG0738	Major facilitator superfamily
AYN53_RS09575	COG2271	Major facilitator Superfamily
AYN53_RS09595	COG1960	acyl-CoA dehydrogenase activity
AYN53_RS09600	COG2207	Transcriptional regulator
AYN53_RS09600	COG1917	Cupin 2, conserved barrel domain protein
AYN53_RS09605	COG2086	electron transfer activity
AYN53_RS09610	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AYN53_RS09615	COG0644	oxidoreductase
AYN53_RS09620	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AYN53_RS09625	COG0318	PFAM AMP-dependent synthetase and ligase
AYN53_RS09630	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AYN53_RS09630	COG0574	Belongs to the PEP-utilizing enzyme family
AYN53_RS09640	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AYN53_RS09650	COG2200	EAL domain
AYN53_RS09655	COG0791	NLP P60 protein
AYN53_RS09665	COG0386	Belongs to the glutathione peroxidase family
AYN53_RS09725	COG3137	Salt-induced outer membrane protein
AYN53_RS09730	COG1105	Belongs to the carbohydrate kinase PfkB family
AYN53_RS09740	COG3001	Fructosamine kinase
AYN53_RS09745	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AYN53_RS09750	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
AYN53_RS09760	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AYN53_RS09765	COG1988	membrane-bound metal-dependent
AYN53_RS09770	COG1823	symporter activity
AYN53_RS09785	COG3394	polysaccharide catabolic process
AYN53_RS09790	COG1486	melibiose metabolic process
AYN53_RS09795	COG1917	Cupin 2, conserved barrel domain protein
AYN53_RS09795	COG2169	Transcriptional regulator
AYN53_RS09800	COG1447	Phosphotransferase system cellobiose-specific component IIA
AYN53_RS09805	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AYN53_RS09810	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AYN53_RS09825	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AYN53_RS09880	COG5301	cellulose 1,4-beta-cellobiosidase activity
AYN53_RS09975	COG4695	Portal protein
AYN53_RS09995	COG1802	Transcriptional regulator
AYN53_RS09995	COG4626	Terminase
AYN53_RS10100	COG0582	viral genome integration into host DNA
AYN53_RS10130	COG3772	lysozyme
AYN53_RS10155	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
AYN53_RS10160	COG1403	HNH endonuclease
AYN53_RS10275	COG0582	viral genome integration into host DNA
AYN53_RS10285	COG3678	ATP-independent chaperone mediated protein folding
AYN53_RS10315	COG0708	Exodeoxyribonuclease III
AYN53_RS10320	COG0398	Pfam SNARE associated Golgi protein
AYN53_RS10330	COG0398	Pfam SNARE associated Golgi protein
AYN53_RS10335	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AYN53_RS10340	COG4134	Bacterial extracellular solute-binding protein
AYN53_RS10345	COG4135	transport system, permease component
AYN53_RS10350	COG4136	ATPase activity
AYN53_RS10355	COG2897	thiosulfate sulfurtransferase activity
AYN53_RS10360	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AYN53_RS10365	COG0494	nUDIX hydrolase
AYN53_RS10375	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AYN53_RS10380	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AYN53_RS10395	COG0778	Nitroreductase
AYN53_RS10405	COG0616	signal peptide processing
AYN53_RS10415	COG0252	asparaginase activity
AYN53_RS10420	COG1335	isochorismatase
AYN53_RS10435	COG3139	Protein of unknown function (DUF1315)
AYN53_RS10445	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AYN53_RS10450	COG0676	glucose-6-phosphate 1-epimerase activity
AYN53_RS10455	COG3713	MltA-interacting MipA family protein
AYN53_RS10460	COG2766	serine protein kinase
AYN53_RS10470	COG2199	diguanylate cyclase activity
AYN53_RS10475	COG2199	diguanylate cyclase activity
AYN53_RS10485	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AYN53_RS10500	COG3189	MarR family transcriptional regulator
AYN53_RS10505	COG3042	response to heat
AYN53_RS10510	COG2199	diguanylate cyclase activity
AYN53_RS10510	COG2203	Gaf domain
AYN53_RS10530	COG3615	Tellurite resistance protein tehB
AYN53_RS10540	COG0583	DNA-binding transcription factor activity
AYN53_RS10545	COG0473	3-isopropylmalate dehydrogenase activity
AYN53_RS10550	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AYN53_RS10555	COG4638	Rieske (2fe-2S)
AYN53_RS10560	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AYN53_RS10565	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AYN53_RS10570	COG0318	PFAM AMP-dependent synthetase and ligase
AYN53_RS10575	COG3065	identical protein binding
AYN53_RS10580	COG1214	PFAM Peptidase M22, glycoprotease
AYN53_RS10585	COG1199	ATP-dependent helicase activity
AYN53_RS10590	COG0251	oxidation-reduction process
AYN53_RS10605	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AYN53_RS10615	COG1760	l-serine dehydratase
AYN53_RS10620	COG2200	EAL domain
AYN53_RS10640	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN53_RS10640	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AYN53_RS10645	COG3715	PTS system
AYN53_RS10650	COG3716	PTS system mannose fructose sorbose family IID component
AYN53_RS10705	COG1414	Transcriptional regulator
AYN53_RS10710	COG2814	Major facilitator Superfamily
AYN53_RS10720	COG0793	Belongs to the peptidase S41A family
AYN53_RS10730	COG1956	GAF domain-containing protein
AYN53_RS10735	COG2995	paraquat-inducible protein a
AYN53_RS10760	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AYN53_RS10785	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AYN53_RS10805	COG1276	copper resistance
AYN53_RS10810	COG2372	response to copper ion
AYN53_RS10820	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AYN53_RS10820	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AYN53_RS10825	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AYN53_RS10830	COG1770	oligopeptidase
AYN53_RS10840	COG3141	response to X-ray
AYN53_RS10850	COG0800	Aldolase
AYN53_RS10855	COG0129	dihydroxy-acid dehydratase activity
AYN53_RS10860	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AYN53_RS10870	COG1737	Transcriptional regulator
AYN53_RS10875	COG0469	pyruvate kinase activity
AYN53_RS10880	COG1560	Kdo2-lipid A biosynthetic process
AYN53_RS10885	COG0739	heme binding
AYN53_RS10890	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AYN53_RS10900	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AYN53_RS10930	COG0217	transcriptional regulatory protein
AYN53_RS10935	COG0494	nUDIX hydrolase
AYN53_RS10945	COG1335	isochorismatase
AYN53_RS10950	COG1801	Protein of unknown function DUF72
AYN53_RS10955	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AYN53_RS10975	COG3005	denitrification pathway
AYN53_RS10985	COG3102	Protein conserved in bacteria
AYN53_RS11000	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AYN53_RS11005	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AYN53_RS11020	COG1360	Flagellar Motor Protein
AYN53_RS11025	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AYN53_RS11040	COG0589	response to stress
AYN53_RS11045	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AYN53_RS11050	COG1877	trehalose-phosphatase activity
AYN53_RS11055	COG1172	Belongs to the binding-protein-dependent transport system permease family
AYN53_RS11075	COG1528	Iron-storage protein
AYN53_RS11095	COG1528	Iron-storage protein
AYN53_RS11105	COG0814	amino acid
AYN53_RS11110	COG3012	SEC-C Motif Domain Protein
AYN53_RS11110	COG3318	Belongs to the UPF0149 family
AYN53_RS11140	COG2197	response regulator
AYN53_RS11150	COG2197	response regulator
AYN53_RS11155	COG1126	abc transporter atp-binding protein
AYN53_RS11160	COG0765	amino acid transport
AYN53_RS11180	COG1191	sigma factor activity
AYN53_RS11185	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AYN53_RS11195	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AYN53_RS11200	COG1516	flagellar protein fliS
AYN53_RS11210	COG0366	Alpha amylase catalytic
AYN53_RS11225	COG2391	methyltransferase activity
AYN53_RS11230	COG0425	Belongs to the sulfur carrier protein TusA family
AYN53_RS11250	COG1766	The M ring may be actively involved in energy transduction
AYN53_RS11255	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AYN53_RS11260	COG1317	bacterial-type flagellum organization
AYN53_RS11265	COG1157	protein secretion by the type III secretion system
AYN53_RS11270	COG2882	bacterial-type flagellum organization
AYN53_RS11275	COG3144	bacterial-type flagellum assembly
AYN53_RS11280	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AYN53_RS11285	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AYN53_RS11290	COG3190	flagellar
AYN53_RS11295	COG1338	Plays a role in the flagellum-specific transport system
AYN53_RS11300	COG1987	bacterial-type flagellum assembly
AYN53_RS11305	COG1684	flagellar biosynthetic protein fliR
AYN53_RS11330	COG5475	Uncharacterized small protein (DUF2158)
AYN53_RS11335	COG2354	Protein conserved in bacteria
AYN53_RS11340	COG0697	spore germination
AYN53_RS11345	COG3727	T/G mismatch-specific endonuclease activity
AYN53_RS11350	COG0270	DNA (cytosine-5-)-methyltransferase activity
AYN53_RS11355	COG1418	mRNA catabolic process
AYN53_RS11375	COG2205	protein histidine kinase activity
AYN53_RS11380	COG0745	RESPONSE REGULATOR receiver
AYN53_RS11385	COG2351	hydroxyisourate hydrolase activity
AYN53_RS11400	COG3443	Belongs to the bacterial solute-binding protein 9 family
AYN53_RS11435	COG5301	cellulose 1,4-beta-cellobiosidase activity
AYN53_RS11515	COG1030	water channel activity
AYN53_RS11535	COG4220	transposase activity
AYN53_RS11565	COG3772	lysozyme
AYN53_RS11610	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
AYN53_RS11615	COG1403	HNH endonuclease
AYN53_RS11660	COG1846	Transcriptional regulator
AYN53_RS11665	COG1484	DNA-dependent DNA replication
AYN53_RS11670	COG1846	Transcriptional regulator
AYN53_RS11680	COG4197	protein conserved in bacteria, prophage-related
AYN53_RS11715	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AYN53_RS11745	COG0583	DNA-binding transcription factor activity
AYN53_RS11775	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AYN53_RS11805	COG1376	ErfK ybiS ycfS ynhG family protein
AYN53_RS11875	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AYN53_RS11890	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
AYN53_RS11900	COG1012	belongs to the aldehyde dehydrogenase family
AYN53_RS11905	COG1012	belongs to the aldehyde dehydrogenase family
AYN53_RS11905	COG1454	alcohol dehydrogenase
AYN53_RS11910	COG4656	Part of a membrane complex involved in electron transport
AYN53_RS11935	COG1289	transmembrane transporter activity
AYN53_RS11945	COG1686	Belongs to the peptidase S11 family
AYN53_RS11950	COG2925	Exonuclease
AYN53_RS11955	COG0531	amino acid
AYN53_RS11965	COG0583	DNA-binding transcription factor activity
AYN53_RS11970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AYN53_RS11990	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AYN53_RS12000	COG0131	Imidazoleglycerol-phosphate dehydratase
AYN53_RS12000	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AYN53_RS12005	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AYN53_RS12025	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
AYN53_RS12030	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AYN53_RS12035	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AYN53_RS12040	COG0438	transferase activity, transferring glycosyl groups
AYN53_RS12095	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AYN53_RS12100	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AYN53_RS12105	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AYN53_RS12115	COG1088	dTDP-glucose 4,6-dehydratase activity
AYN53_RS12120	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AYN53_RS12130	COG1253	flavin adenine dinucleotide binding
AYN53_RS12135	COG2982	Protein involved in outer membrane biogenesis
AYN53_RS12145	COG0572	uridine kinase
AYN53_RS12150	COG5001	Diguanylate cyclase
AYN53_RS12150	COG3447	MASE1 domain protein
AYN53_RS12150	COG5002	protein histidine kinase activity
AYN53_RS12155	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AYN53_RS12160	COG0443	Heat shock 70 kDa protein
AYN53_RS12220	COG5301	cellulose 1,4-beta-cellobiosidase activity
AYN53_RS12285	COG4220	transposase activity
AYN53_RS12295	COG3646	Phage regulatory protein
AYN53_RS12305	COG3772	lysozyme
AYN53_RS12385	COG2205	protein histidine kinase activity
AYN53_RS12390	COG0745	RESPONSE REGULATOR receiver
AYN53_RS12400	COG0826	peptidase U32
AYN53_RS12425	COG1830	Aldolase
AYN53_RS12430	COG2211	Major facilitator Superfamily
AYN53_RS12435	COG1397	ADP-ribosylglycohydrolase
AYN53_RS12440	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AYN53_RS12445	COG2188	Transcriptional regulator
AYN53_RS12465	COG3757	hydrolase, family 25
AYN53_RS12470	COG0351	phosphomethylpyrimidine kinase
AYN53_RS12490	COG5455	response to cobalt ion
AYN53_RS12495	COG3539	Fimbrial protein
AYN53_RS12505	COG3121	Chaperone
AYN53_RS12510	COG3539	Fimbrial protein
AYN53_RS12520	COG0489	protein tyrosine kinase activity
AYN53_RS12535	COG3831	ATPase activity
AYN53_RS12550	COG2425	protein containing a von Willebrand factor type A (vWA) domain
AYN53_RS12555	COG3552	Protein containing von Willebrand factor type A (VWA) domain
AYN53_RS12560	COG4715	Zinc finger, swim domain protein
AYN53_RS12565	COG4808	Protein conserved in bacteria
AYN53_RS12570	COG4807	Protein conserved in bacteria
AYN53_RS12575	COG3279	Response regulator of the LytR AlgR family
AYN53_RS12580	COG3275	phosphorelay sensor kinase activity
AYN53_RS12585	COG0789	Transcriptional regulator
AYN53_RS12595	COG1174	glycine betaine transport
AYN53_RS12600	COG1125	glycine betaine transport
AYN53_RS12605	COG1174	glycine betaine transport
AYN53_RS12610	COG1732	Glycine betaine
AYN53_RS12615	COG1472	Belongs to the glycosyl hydrolase 3 family
AYN53_RS12620	COG0277	FAD linked oxidase domain protein
AYN53_RS12625	COG1686	Belongs to the peptidase S11 family
AYN53_RS12635	COG0586	Pfam SNARE associated Golgi protein
AYN53_RS12645	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AYN53_RS12655	COG1346	cytolysis
AYN53_RS12665	COG2949	membrane
AYN53_RS12680	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AYN53_RS12680	COG0167	dihydroorotate dehydrogenase activity
AYN53_RS12685	COG4211	Belongs to the binding-protein-dependent transport system permease family
AYN53_RS12690	COG1129	ABC transporter
AYN53_RS12695	COG1879	ABC-type sugar transport system periplasmic component
AYN53_RS12700	COG1609	Transcriptional regulator
AYN53_RS12710	COG2311	Membrane
AYN53_RS12730	COG4771	TonB-dependent receptor
AYN53_RS12740	COG0833	amino acid
AYN53_RS12750	COG0583	DNA-binding transcription factor activity
AYN53_RS12755	COG2855	membrane
AYN53_RS12765	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AYN53_RS12765	COG1522	sequence-specific DNA binding
AYN53_RS12770	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AYN53_RS12775	COG2313	pseudouridylate synthase activity
AYN53_RS12780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AYN53_RS12785	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AYN53_RS12785	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AYN53_RS12785	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AYN53_RS12790	COG1105	Belongs to the carbohydrate kinase PfkB family
AYN53_RS12795	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN53_RS12795	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN53_RS12800	COG2814	Major facilitator Superfamily
AYN53_RS12815	COG0246	Mannitol dehydrogenase
AYN53_RS12820	COG0523	cobalamin synthesis protein
AYN53_RS12825	COG0671	phosphoesterase, PA-phosphatase related
AYN53_RS12830	COG0791	NLP P60 protein
AYN53_RS12835	COG2200	EAL domain
AYN53_RS12840	COG4166	transmembrane transport
AYN53_RS12845	COG4174	ABC transporter (Permease)
AYN53_RS12850	COG4239	(ABC) transporter, permease
AYN53_RS12855	COG4172	Belongs to the ABC transporter superfamily
AYN53_RS12865	COG2814	Major facilitator Superfamily
AYN53_RS12870	COG1187	pseudouridine synthase activity
AYN53_RS12880	COG1061	Type III restriction enzyme res subunit
AYN53_RS12895	COG0431	NADPH-dependent FMN reductase
AYN53_RS12895	COG1053	succinate dehydrogenase
AYN53_RS12895	COG3976	FMN-binding domain protein
AYN53_RS12900	COG3005	denitrification pathway
AYN53_RS12915	COG3083	sulfuric ester hydrolase activity
AYN53_RS12925	COG0582	viral genome integration into host DNA
AYN53_RS12975	COG2197	response regulator
AYN53_RS12980	COG4235	cytochrome complex assembly
AYN53_RS12980	COG3088	subunit of a heme lyase
AYN53_RS12985	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AYN53_RS12990	COG1138	Cytochrome C-type biogenesis protein
AYN53_RS13000	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AYN53_RS13005	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AYN53_RS13010	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AYN53_RS13015	COG4133	protoheme IX ABC transporter activity
AYN53_RS13020	COG3005	denitrification pathway
AYN53_RS13025	COG3043	anaerobic respiration
AYN53_RS13030	COG0348	domain, Protein
AYN53_RS13035	COG0437	4 iron, 4 sulfur cluster binding
AYN53_RS13045	COG3062	negative regulation of establishment of protein localization
AYN53_RS13050	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AYN53_RS13050	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
AYN53_RS13070	COG4615	Cyclic peptide transporter
AYN53_RS13075	COG3145	DNA-N1-methyladenine dioxygenase activity
AYN53_RS13085	COG1477	protein flavinylation
AYN53_RS13100	COG2198	Histidine kinase
AYN53_RS13100	COG0642	Histidine kinase
AYN53_RS13105	COG2197	response regulator
AYN53_RS13110	COG2205	protein histidine kinase activity
AYN53_RS13110	COG0784	Response regulator, receiver
AYN53_RS13120	COG4676	Protein conserved in bacteria
AYN53_RS13125	COG5445	Predicted secreted protein (DUF2300)
AYN53_RS13135	COG3234	Protein of unknown function (DUF1175)
AYN53_RS13140	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
AYN53_RS13145	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AYN53_RS13155	COG3468	outer membrane autotransporter barrel domain protein
AYN53_RS13165	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AYN53_RS13170	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AYN53_RS13175	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AYN53_RS13180	COG2814	Major facilitator Superfamily
AYN53_RS13185	COG0583	DNA-binding transcription factor activity
AYN53_RS13190	COG0584	glycerophosphoryl diester phosphodiesterase
AYN53_RS13195	COG2271	Major facilitator Superfamily
AYN53_RS13200	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AYN53_RS13210	COG0247	lactate metabolic process
AYN53_RS13215	COG5464	transposase or invertase
AYN53_RS13225	COG2271	Major facilitator Superfamily
AYN53_RS13235	COG1414	Transcriptional regulator
AYN53_RS13300	COG0318	PFAM AMP-dependent synthetase and ligase
AYN53_RS13310	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AYN53_RS13325	COG1169	isochorismate synthase
AYN53_RS13330	COG4575	ribosome binding
AYN53_RS13335	COG2153	protein acetylation
AYN53_RS13350	COG2234	aminopeptidase activity
AYN53_RS13365	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AYN53_RS13370	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AYN53_RS13380	COG0839	Belongs to the complex I subunit 6 family
AYN53_RS13395	COG1034	ATP synthesis coupled electron transport
AYN53_RS13400	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AYN53_RS13405	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AYN53_RS13425	COG0583	DNA-binding transcription factor activity
AYN53_RS13435	COG0436	Aminotransferase
AYN53_RS13445	COG0490	domain, Protein
AYN53_RS13445	COG0471	metal ion transport
AYN53_RS13450	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AYN53_RS13465	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AYN53_RS13470	COG0280	phosphate acetyltransferase
AYN53_RS13470	COG0857	belongs to the CobB CobQ family
AYN53_RS13475	COG1288	antiporter activity
AYN53_RS13480	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AYN53_RS13485	COG3959	Transketolase, thiamine diphosphate binding domain
AYN53_RS13490	COG3037	sugar-specific permease SgaT UlaA
AYN53_RS13500	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN53_RS13505	COG1609	Transcriptional regulator
AYN53_RS13510	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AYN53_RS13515	COG0622	Phosphoesterase
AYN53_RS13525	COG0625	glutathione transferase activity
AYN53_RS13530	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AYN53_RS13535	COG1090	epimerase
AYN53_RS13540	COG5464	transposase or invertase
AYN53_RS13545	COG4598	ABC transporter
AYN53_RS13550	COG4160	amino acid transport
AYN53_RS13555	COG4215	(ABC) transporter
AYN53_RS13560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AYN53_RS13565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AYN53_RS13570	COG0163	prenyltransferase activity
AYN53_RS13575	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AYN53_RS13580	COG1286	toxin biosynthetic process
AYN53_RS13585	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AYN53_RS13590	COG0285	dihydrofolate synthase activity
AYN53_RS13600	COG0586	Pfam SNARE associated Golgi protein
AYN53_RS13610	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AYN53_RS13625	COG2814	Major facilitator Superfamily
AYN53_RS13630	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AYN53_RS13645	COG3101	peptidyl-lysine hydroxylation
AYN53_RS13650	COG0730	response to heat
AYN53_RS13685	COG3539	Fimbrial protein
AYN53_RS13690	COG3539	Fimbrial protein
AYN53_RS13695	COG3539	Fimbrial protein
AYN53_RS13705	COG2062	phosphohistidine phosphatase, SixA
AYN53_RS13710	COG1024	Enoyl-CoA hydratase
AYN53_RS13710	COG1250	3-hydroxyacyl-CoA dehydrogenase
AYN53_RS13720	COG3691	Protein conserved in bacteria
AYN53_RS13730	COG2067	long-chain fatty acid transport protein
AYN53_RS13735	COG2853	Lipoprotein
AYN53_RS13745	COG0582	viral genome integration into host DNA
AYN53_RS13850	COG1783	phage Terminase large subunit
AYN53_RS13870	COG3646	Phage regulatory protein
AYN53_RS13990	COG4712	double-strand break repair protein
AYN53_RS14050	COG0583	DNA-binding transcription factor activity
AYN53_RS14055	COG2610	gluconate transmembrane transporter activity
AYN53_RS14075	COG1560	Kdo2-lipid A biosynthetic process
AYN53_RS14085	COG0436	Aminotransferase
AYN53_RS14090	COG3275	phosphorelay sensor kinase activity
AYN53_RS14095	COG3279	Response regulator of the LytR AlgR family
AYN53_RS14100	COG2207	Transcriptional regulator
AYN53_RS14105	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN53_RS14105	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AYN53_RS14105	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN53_RS14110	COG1363	Peptidase, m42
AYN53_RS14115	COG0006	proline dipeptidase activity
AYN53_RS14120	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AYN53_RS14125	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AYN53_RS14150	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AYN53_RS14155	COG2199	diguanylate cyclase activity
AYN53_RS14155	COG2200	EAL domain
AYN53_RS14170	COG3415	Transposase
AYN53_RS14175	COG3415	Transposase
AYN53_RS14200	COG0583	DNA-binding transcription factor activity
AYN53_RS14205	COG2211	Major facilitator Superfamily
AYN53_RS14210	COG2211	Major facilitator Superfamily
AYN53_RS14215	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AYN53_RS14225	COG2211	Major facilitator Superfamily
AYN53_RS14230	COG0385	Bile acid
AYN53_RS14255	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AYN53_RS14260	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN53_RS14265	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AYN53_RS14270	COG2190	(PTS) system
AYN53_RS14285	COG4884	unkown
AYN53_RS14285	COG3831	ATPase activity
AYN53_RS14295	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AYN53_RS14300	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AYN53_RS14305	COG4208	sulfate ABC transporter
AYN53_RS14310	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AYN53_RS14315	COG4150	thiosulfate binding
AYN53_RS14320	COG1028	Short-chain dehydrogenase reductase Sdr
AYN53_RS14340	COG2837	iron assimilation
AYN53_RS14360	COG0860	N-Acetylmuramoyl-L-alanine amidase
AYN53_RS14380	COG2207	Transcriptional regulator
AYN53_RS14385	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AYN53_RS14390	COG4816	utilization protein
AYN53_RS14400	COG4303	Ethanolamine ammonia lyase large subunit
AYN53_RS14415	COG1454	alcohol dehydrogenase
AYN53_RS14420	COG4820	ethanolamine utilization protein (EutJ)
AYN53_RS14425	COG1012	belongs to the aldehyde dehydrogenase family
AYN53_RS14430	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
AYN53_RS14435	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AYN53_RS14440	COG0280	phosphate acetyltransferase
AYN53_RS14445	COG4812	Cobalamin adenosyltransferase
AYN53_RS14455	COG4917	ethanolamine utilization protein
AYN53_RS14460	COG4810	utilization protein
AYN53_RS14465	COG0281	malic enzyme
AYN53_RS14465	COG0280	phosphate acetyltransferase
AYN53_RS14475	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AYN53_RS14480	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AYN53_RS14490	COG0493	'glutamate synthase
AYN53_RS14490	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AYN53_RS14495	COG3850	Histidine kinase
AYN53_RS14500	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AYN53_RS14510	COG1393	Belongs to the ArsC family
AYN53_RS14525	COG0400	carboxylic ester hydrolase activity
AYN53_RS14530	COG1444	tRNA N-acetyltransferase activity
AYN53_RS14535	COG2321	neutral zinc metallopeptidase
AYN53_RS14545	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AYN53_RS14555	COG2716	regulation of RNA biosynthetic process
AYN53_RS14560	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AYN53_RS14565	COG0628	permease
AYN53_RS14575	COG4783	chaperone-mediated protein folding
AYN53_RS14580	COG1393	Belongs to the ArsC family
AYN53_RS14590	COG2233	PERMEase
AYN53_RS14610	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AYN53_RS14615	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AYN53_RS14620	COG0248	Ppx GppA phosphatase
AYN53_RS14625	COG2200	EAL domain
AYN53_RS14640	COG3133	Outer membrane lipoprotein
AYN53_RS14655	COG0516	GMP reductase activity
AYN53_RS14655	COG0517	IMP dehydrogenase activity
AYN53_RS14680	COG1645	bacterial-type flagellum-dependent swarming motility
AYN53_RS14695	COG2976	Protein conserved in bacteria
AYN53_RS14725	COG4953	penicillin-binding protein 1C
AYN53_RS14730	COG2373	Large extracellular alpha-helical protein
AYN53_RS14735	COG2897	thiosulfate sulfurtransferase activity
AYN53_RS14750	COG2975	iron-sulfur cluster assembly
AYN53_RS14755	COG0633	Ferredoxin
AYN53_RS14775	COG0822	iron-sulfur transferase activity
AYN53_RS14795	COG0483	inositol monophosphate 1-phosphatase activity
AYN53_RS14800	COG1073	alpha beta
AYN53_RS14805	COG3711	transcriptional antiterminator
AYN53_RS14810	COG2814	Major facilitator Superfamily
AYN53_RS14820	COG2259	Doxx family
AYN53_RS14825	COG2017	converts alpha-aldose to the beta-anomer
AYN53_RS14830	COG1063	alcohol dehydrogenase
AYN53_RS14835	COG1172	Belongs to the binding-protein-dependent transport system permease family
AYN53_RS14840	COG1129	ABC transporter
AYN53_RS14845	COG1879	ABC-type sugar transport system periplasmic component
AYN53_RS14850	COG0457	Tetratricopeptide repeat
AYN53_RS14855	COG1940	carbohydrate kinase activity
AYN53_RS14865	COG1017	nitric oxide dioxygenase activity
AYN53_RS14865	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AYN53_RS14870	COG0347	Belongs to the P(II) protein family
AYN53_RS14875	COG2204	response regulator
AYN53_RS14880	COG3170	Tfp pilus assembly protein FimV
AYN53_RS14885	COG2205	protein histidine kinase activity
AYN53_RS14895	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AYN53_RS14895	COG0047	phosphoribosylformylglycinamidine synthase activity
AYN53_RS14910	COG0560	Phosphoserine phosphatase
AYN53_RS14915	COG1737	Transcriptional regulator
AYN53_RS14920	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AYN53_RS14945	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AYN53_RS14970	COG0681	Belongs to the peptidase S26 family
AYN53_RS14980	COG3086	response to oxidative stress
AYN53_RS14985	COG3026	antisigma factor binding
AYN53_RS14990	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
AYN53_RS14995	COG1595	DNA-templated transcription, initiation
AYN53_RS15000	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AYN53_RS15010	COG0513	Belongs to the DEAD box helicase family
AYN53_RS15015	COG0583	DNA-binding transcription factor activity
AYN53_RS15045	COG2271	Major facilitator Superfamily
AYN53_RS15060	COG2086	electron transfer activity
AYN53_RS15065	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AYN53_RS15080	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AYN53_RS15090	COG3118	belongs to the thioredoxin family
AYN53_RS15095	COG3148	PFAM DTW domain containing protein
AYN53_RS15100	COG0045	succinate-CoA ligase (ADP-forming) activity
AYN53_RS15100	COG1042	CoA-binding domain protein
AYN53_RS15100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AYN53_RS15105	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AYN53_RS15110	COG5544	Lipoprotein
AYN53_RS15115	COG0477	Major facilitator Superfamily
AYN53_RS15150	COG0542	response to heat
AYN53_RS15160	COG0564	pseudouridine synthase activity
AYN53_RS15165	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AYN53_RS15175	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AYN53_RS15185	COG0077	Prephenate dehydratase
AYN53_RS15185	COG1605	Chorismate mutase
AYN53_RS15190	COG1605	Chorismate mutase
AYN53_RS15190	COG0287	Prephenate dehydrogenase
AYN53_RS15195	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AYN53_RS15210	COG2199	diguanylate cyclase activity
AYN53_RS15215	COG2885	chlorophyll binding
AYN53_RS15240	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AYN53_RS15245	COG4137	Cytochrome C assembly protein
AYN53_RS15250	COG4536	flavin adenine dinucleotide binding
AYN53_RS15270	COG0497	DNA recombination
AYN53_RS15275	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AYN53_RS15285	COG2867	negative regulation of translational initiation
AYN53_RS15345	COG0727	PFAM Uncharacterised protein family (UPF0153)
AYN53_RS15375	COG5301	cellulose 1,4-beta-cellobiosidase activity
AYN53_RS15485	COG3772	lysozyme
AYN53_RS15530	COG0305	Participates in initiation and elongation during chromosome replication
AYN53_RS15535	COG1484	DNA-dependent DNA replication
AYN53_RS15565	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AYN53_RS15625	COG0582	viral genome integration into host DNA
AYN53_RS15655	COG0366	Alpha amylase catalytic
AYN53_RS15665	COG0579	oxidoreductase
AYN53_RS15670	COG1012	belongs to the aldehyde dehydrogenase family
AYN53_RS15675	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AYN53_RS15680	COG1113	amino acid transport
AYN53_RS15685	COG1802	Transcriptional regulator
AYN53_RS15690	COG0401	homolog of Blt101
AYN53_RS15695	COG0640	Transcriptional regulator
AYN53_RS15700	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AYN53_RS15705	COG2916	Histone family protein nucleoid-structuring protein H-NS
AYN53_RS15720	COG4575	ribosome binding
AYN53_RS15730	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AYN53_RS15740	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AYN53_RS15750	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AYN53_RS15755	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AYN53_RS15765	COG4175	Glycine betaine
AYN53_RS15770	COG4176	ABC-type proline glycine betaine transport system permease component
AYN53_RS15775	COG2113	Glycine betaine
AYN53_RS15780	COG2814	Major facilitator Superfamily
AYN53_RS15785	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AYN53_RS15795	COG1846	Transcriptional regulator
AYN53_RS15800	COG1566	PFAM secretion protein HlyD family protein
AYN53_RS15805	COG2814	Major facilitator Superfamily
AYN53_RS15825	COG1238	metal cluster binding
AYN53_RS15830	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AYN53_RS15860	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AYN53_RS15880	COG1546	Belongs to the CinA family
AYN53_RS15885	COG2951	lytic endotransglycosylase activity
AYN53_RS15890	COG3730	PTS system glucitol sorbitol-specific
AYN53_RS15895	COG3732	PTS system glucitol sorbitol-specific
AYN53_RS15905	COG1028	Short-chain dehydrogenase reductase Sdr
AYN53_RS15910	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN53_RS15915	COG1349	DNA-binding transcription factor activity
AYN53_RS15920	COG0517	IMP dehydrogenase activity
AYN53_RS15920	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AYN53_RS15925	COG3604	Transcriptional regulator
AYN53_RS15940	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AYN53_RS15945	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AYN53_RS15955	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AYN53_RS15965	COG3260	NADH ubiquinone oxidoreductase 20
AYN53_RS15970	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AYN53_RS15975	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AYN53_RS15975	COG3261	NADH dehydrogenase
AYN53_RS15980	COG0650	Formate hydrogenlyase subunit 4
AYN53_RS15985	COG0651	ATP synthesis coupled electron transport
AYN53_RS15990	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AYN53_RS16000	COG0375	protein maturation
AYN53_RS16005	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AYN53_RS16010	COG0298	carbon dioxide binding
AYN53_RS16015	COG0409	Hydrogenase expression formation protein
AYN53_RS16020	COG0309	Hydrogenase expression formation protein (HypE)
AYN53_RS16025	COG3604	Transcriptional regulator
AYN53_RS16050	COG1349	DNA-binding transcription factor activity
AYN53_RS16055	COG2084	Dehydrogenase
AYN53_RS16060	COG3395	kinase activity
AYN53_RS16065	COG0235	Class ii aldolase
AYN53_RS16070	COG3622	Belongs to the hyi family
AYN53_RS16075	COG2610	gluconate transmembrane transporter activity
AYN53_RS16085	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AYN53_RS16090	COG0163	prenyltransferase activity
AYN53_RS16100	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AYN53_RS16105	COG1388	LysM domain
AYN53_RS16105	COG4942	peptidase
AYN53_RS16120	COG0585	pseudouridine synthase activity
AYN53_RS16165	COG2234	aminopeptidase activity
AYN53_RS16170	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AYN53_RS16175	COG1518	maintenance of DNA repeat elements
AYN53_RS16190	COG1857	crispr-associated protein
AYN53_RS16205	COG1203	CRISPR-associated helicase, Cas3
AYN53_RS16210	COG3385	transposase activity
AYN53_RS16245	COG0720	synthase
AYN53_RS16250	COG0644	oxidoreductase
AYN53_RS16255	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AYN53_RS16260	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AYN53_RS16265	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AYN53_RS16270	COG2086	electron transfer activity
AYN53_RS16275	COG0477	Major facilitator Superfamily
AYN53_RS16280	COG0277	FAD linked oxidase domain protein
AYN53_RS16290	COG2223	nitrite transmembrane transporter activity
AYN53_RS16295	COG1070	Carbohydrate kinase
AYN53_RS16300	COG0602	queuosine metabolic process
AYN53_RS16310	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AYN53_RS16320	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AYN53_RS16335	COG3956	TIGRFAM MazG family protein
AYN53_RS16340	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AYN53_RS16345	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AYN53_RS16350	COG3850	Histidine kinase
AYN53_RS16350	COG4999	Histidine kinase
AYN53_RS16350	COG3437	response regulator, receiver
AYN53_RS16350	COG2205	protein histidine kinase activity
AYN53_RS16355	COG0716	FMN binding
AYN53_RS16360	COG0564	pseudouridine synthase activity
AYN53_RS16365	COG3098	single-species biofilm formation
AYN53_RS16380	COG1611	Belongs to the LOG family
AYN53_RS16385	COG0814	amino acid
AYN53_RS16390	COG1760	l-serine dehydratase
AYN53_RS16405	COG0235	Class ii aldolase
AYN53_RS16410	COG0738	Major facilitator superfamily
AYN53_RS16420	COG1070	Carbohydrate kinase
AYN53_RS16430	COG1349	DNA-binding transcription factor activity
AYN53_RS16440	COG2363	Small membrane protein
AYN53_RS16445	COG0583	DNA-binding transcription factor activity
AYN53_RS16455	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AYN53_RS16460	COG2166	iron-sulfur cluster assembly
AYN53_RS16465	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AYN53_RS16470	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AYN53_RS16495	COG0860	N-Acetylmuramoyl-L-alanine amidase
AYN53_RS16505	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AYN53_RS16505	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AYN53_RS16510	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AYN53_RS16515	COG1074	ATP-dependent DNA helicase activity
AYN53_RS16520	COG1025	Belongs to the peptidase M16 family
AYN53_RS16525	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AYN53_RS16530	COG4967	type IV pilus modification protein PilV
AYN53_RS16540	COG4795	General secretion pathway protein
AYN53_RS16545	COG2165	general secretion pathway protein
AYN53_RS16560	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
AYN53_RS16575	COG0861	Integral membrane protein TerC family
AYN53_RS16585	COG0667	Aldo Keto reductase
AYN53_RS16605	COG1609	Transcriptional regulator
AYN53_RS16615	COG0583	DNA-binding transcription factor activity
AYN53_RS16625	COG0183	Belongs to the thiolase family
AYN53_RS16630	COG0814	amino acid
AYN53_RS16635	COG2771	luxR family
AYN53_RS16655	COG0457	Tetratricopeptide repeat
AYN53_RS16660	COG3710	Transcriptional regulator
AYN53_RS16660	COG0457	Tetratricopeptide repeat
AYN53_RS16670	COG0741	lytic transglycosylase activity
AYN53_RS16675	COG2197	response regulator
AYN53_RS16775	COG2207	Transcriptional regulator
AYN53_RS16785	COG3387	PFAM Glycoside hydrolase 15-related
AYN53_RS16795	COG4942	peptidase
AYN53_RS16800	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AYN53_RS16810	COG2080	2 iron, 2 sulfur cluster binding
AYN53_RS16820	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AYN53_RS16825	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AYN53_RS16830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AYN53_RS16840	COG0549	Belongs to the carbamate kinase family
AYN53_RS16845	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AYN53_RS16845	COG3608	succinylglutamate desuccinylase aspartoacylase
AYN53_RS16850	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AYN53_RS16855	COG2068	MobA-Related Protein
AYN53_RS16865	COG0402	S-adenosylhomocysteine deaminase activity
AYN53_RS16870	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AYN53_RS16875	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AYN53_RS16875	COG2080	2 iron, 2 sulfur cluster binding
AYN53_RS16880	COG2233	PERMEase
AYN53_RS16885	COG0402	S-adenosylhomocysteine deaminase activity
AYN53_RS16890	COG2252	PERMEase
AYN53_RS16895	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AYN53_RS16900	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AYN53_RS16900	COG0493	'glutamate synthase
AYN53_RS16905	COG2233	PERMEase
AYN53_RS16915	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AYN53_RS16920	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AYN53_RS16930	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AYN53_RS16935	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AYN53_RS16940	COG4974	Belongs to the 'phage' integrase family
AYN53_RS16945	COG0716	FMN binding
AYN53_RS16955	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AYN53_RS16965	COG1272	protein, Hemolysin III
AYN53_RS16975	COG2723	6-phospho-beta-galactosidase activity
AYN53_RS17005	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AYN53_RS17010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AYN53_RS17015	COG0006	proline dipeptidase activity
AYN53_RS17040	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AYN53_RS17045	COG1454	alcohol dehydrogenase
AYN53_RS17050	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN53_RS17070	COG3414	Phosphotransferase system galactitol-specific IIB component
AYN53_RS17085	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AYN53_RS17110	COG0583	DNA-binding transcription factor activity
AYN53_RS17115	COG2968	Membrane
AYN53_RS17120	COG1279	arginine transmembrane transporter activity
AYN53_RS17130	COG0668	transmembrane transport
AYN53_RS17135	COG0191	fructose-bisphosphate aldolase activity
AYN53_RS17155	COG1072	(Pantothenic acid kinase))
AYN53_RS17165	COG1494	fructose-1,6-bisphosphatase
AYN53_RS17170	COG1063	alcohol dehydrogenase
AYN53_RS17175	COG2213	PTS system mannitol-specific
AYN53_RS17180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN53_RS17185	COG0330	HflC and HflK could
AYN53_RS17190	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AYN53_RS17195	COG0501	Belongs to the peptidase M48B family
AYN53_RS17220	COG4948	Mandelate Racemase Muconate Lactonizing
AYN53_RS17230	COG1028	Short-chain dehydrogenase reductase Sdr
AYN53_RS17235	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AYN53_RS17240	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AYN53_RS17250	COG1166	arginine decarboxylase activity
AYN53_RS17275	COG2814	Major facilitator Superfamily
AYN53_RS17285	COG2356	endonuclease I
AYN53_RS17290	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AYN53_RS17295	COG0189	ligase activity
AYN53_RS17310	COG2805	Type II/IV secretion system protein
AYN53_RS17315	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AYN53_RS17320	COG0762	integral membrane protein
AYN53_RS17335	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AYN53_RS17345	COG0252	asparaginase activity
AYN53_RS17355	COG3171	Protein conserved in bacteria
AYN53_RS17370	COG1194	a g-specific adenine glycosylase
AYN53_RS17385	COG2211	Major facilitator Superfamily
AYN53_RS17390	COG1982	Orn Lys Arg decarboxylase major
AYN53_RS17400	COG1811	Na channel or pump
AYN53_RS17415	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AYN53_RS17430	COG0583	DNA-binding transcription factor activity
AYN53_RS17435	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AYN53_RS17465	COG2165	general secretion pathway protein
AYN53_RS17470	COG1459	type II secretion system
AYN53_RS17475	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AYN53_RS17485	COG3031	protein transport across the cell outer membrane
AYN53_RS17505	COG3064	Membrane
AYN53_RS17515	COG1620	l-lactate permease
AYN53_RS17520	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AYN53_RS17525	COG3193	protein, possibly involved in utilization of glycolate and propanediol
AYN53_RS17530	COG0247	lactate metabolic process
AYN53_RS17535	COG0277	FAD linked oxidase domain protein
AYN53_RS17540	COG0277	FAD linked oxidase domain protein
AYN53_RS17545	COG2186	Transcriptional regulator
AYN53_RS17550	COG0456	acetyltransferase
AYN53_RS17555	COG0318	PFAM AMP-dependent synthetase and ligase
AYN53_RS17565	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AYN53_RS17570	COG0156	8-amino-7-oxononanoate synthase activity
AYN53_RS17580	COG0795	lipopolysaccharide-transporting ATPase activity
AYN53_RS17585	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AYN53_RS17595	COG2244	polysaccharide biosynthetic process
AYN53_RS17600	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AYN53_RS17605	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AYN53_RS17610	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AYN53_RS17615	COG0306	phosphate transporter
AYN53_RS17620	COG0754	glutathionylspermidine amidase activity
AYN53_RS17625	COG0625	glutathione transferase activity
AYN53_RS17630	COG0298	carbon dioxide binding
AYN53_RS17640	COG1773	rubredoxin
AYN53_RS17645	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AYN53_RS17650	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AYN53_RS17655	COG5557	Pfam Polysulphide reductase, NrfD
AYN53_RS17660	COG0437	4 iron, 4 sulfur cluster binding
AYN53_RS17665	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AYN53_RS17675	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AYN53_RS17680	COG0644	oxidoreductase
AYN53_RS17685	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AYN53_RS17690	COG2086	electron transfer activity
AYN53_RS17695	COG1960	acyl-CoA dehydrogenase activity
AYN53_RS17700	COG2610	gluconate transmembrane transporter activity
AYN53_RS17715	COG1924	4 iron, 4 sulfur cluster binding
AYN53_RS17725	COG0318	PFAM AMP-dependent synthetase and ligase
AYN53_RS17730	COG4977	sequence-specific DNA binding
AYN53_RS17740	COG0667	Aldo Keto reductase
AYN53_RS17745	COG0848	biopolymer transport protein
AYN53_RS17750	COG0811	peptide transport
AYN53_RS17760	COG0626	cystathionine gamma-synthase activity
AYN53_RS17765	COG0586	Pfam SNARE associated Golgi protein
AYN53_RS17770	COG2207	Transcriptional regulator
AYN53_RS17775	COG1979	alcohol dehydrogenase
AYN53_RS17780	COG0656	L-ascorbic acid biosynthetic process
AYN53_RS17785	COG0471	metal ion transport
AYN53_RS17805	COG4238	major outer membrane lipoprotein
AYN53_RS17810	COG1032	radical SAM domain protein
AYN53_RS17815	COG2186	Transcriptional regulator
AYN53_RS17820	COG0246	Mannitol dehydrogenase
AYN53_RS17825	COG1063	alcohol dehydrogenase
AYN53_RS17830	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AYN53_RS17865	COG2132	Multicopper oxidase
AYN53_RS17870	COG0204	Acyl-transferase
AYN53_RS17875	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AYN53_RS17880	COG4166	transmembrane transport
AYN53_RS17885	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AYN53_RS17890	COG3111	PFAM Bacterial OB fold (BOF) protein
AYN53_RS17895	COG0745	RESPONSE REGULATOR receiver
AYN53_RS17900	COG0642	Histidine kinase
AYN53_RS17905	COG2249	NAD(P)H dehydrogenase (quinone) activity
AYN53_RS17910	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AYN53_RS17915	COG0187	DNA topoisomerase II activity
AYN53_RS17920	COG3150	esterase
AYN53_RS17925	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AYN53_RS17930	COG3151	Protein conserved in bacteria
AYN53_RS17935	COG0494	nUDIX hydrolase
AYN53_RS17940	COG1538	Outer membrane efflux protein
AYN53_RS17955	COG0754	glutathionylspermidine amidase activity
AYN53_RS17965	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AYN53_RS17975	COG3384	dioxygenase
AYN53_RS18005	COG1585	Membrane protein implicated in regulation of membrane protease activity
AYN53_RS18050	COG3025	triphosphatase activity
AYN53_RS18060	COG4991	sh3 domain protein
AYN53_RS18075	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AYN53_RS18095	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AYN53_RS18100	COG0471	metal ion transport
AYN53_RS18115	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AYN53_RS18130	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AYN53_RS18145	COG2375	cellular response to nickel ion
AYN53_RS18155	COG1695	Transcriptional regulator
AYN53_RS18170	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AYN53_RS18180	COG1609	Transcriptional regulator
AYN53_RS18185	COG3250	beta-galactosidase activity
AYN53_RS18190	COG2731	YhcH YjgK YiaL family protein
AYN53_RS18195	COG0531	amino acid
AYN53_RS18205	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
AYN53_RS18205	COG3408	Glycogen debranching enzyme
AYN53_RS18210	COG0446	pyridine nucleotide-disulphide oxidoreductase
AYN53_RS18210	COG1902	pentaerythritol trinitrate reductase activity
AYN53_RS18220	COG1451	nucleotide metabolic process
AYN53_RS18225	COG2949	membrane
AYN53_RS18230	COG0673	inositol 2-dehydrogenase activity
AYN53_RS18240	COG0861	Integral membrane protein TerC family
AYN53_RS18245	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AYN53_RS18255	COG2721	sulfolactate sulfo-lyase activity
AYN53_RS18265	COG2271	Major facilitator Superfamily
AYN53_RS18290	COG2186	Transcriptional regulator
AYN53_RS18295	COG0586	Pfam SNARE associated Golgi protein
AYN53_RS18305	COG1422	Protein of unknown function (DUF1090)
AYN53_RS18310	COG4575	ribosome binding
AYN53_RS18315	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
AYN53_RS18325	COG2259	Doxx family
AYN53_RS18335	COG0435	Glutathione S-transferase
AYN53_RS18340	COG3152	Membrane
AYN53_RS18345	COG0583	DNA-binding transcription factor activity
AYN53_RS18350	COG1741	Belongs to the pirin family
AYN53_RS18365	COG0814	amino acid
AYN53_RS18370	COG1760	l-serine dehydratase
AYN53_RS18375	COG0251	oxidation-reduction process
AYN53_RS18380	COG1882	Formate acetyltransferase
AYN53_RS18385	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AYN53_RS18395	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AYN53_RS18400	COG0583	DNA-binding transcription factor activity
AYN53_RS18415	COG1929	Belongs to the glycerate kinase type-1 family
AYN53_RS18420	COG2084	Dehydrogenase
AYN53_RS18430	COG2271	Major facilitator Superfamily
AYN53_RS18435	COG2721	sulfolactate sulfo-lyase activity
AYN53_RS18440	COG1349	DNA-binding transcription factor activity
AYN53_RS18455	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AYN53_RS18465	COG3716	PTS system mannose fructose sorbose family IID component
AYN53_RS18475	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AYN53_RS18495	COG2222	sugar isomerase
AYN53_RS18510	COG3715	PTS system
AYN53_RS18515	COG3716	PTS system mannose fructose sorbose family IID component
AYN53_RS18525	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AYN53_RS18530	COG3107	peptidoglycan biosynthetic process
AYN53_RS18545	COG2823	Periplasmic or secreted lipoprotein
AYN53_RS18550	COG0702	epimerase
AYN53_RS18565	COG3153	acetyltransferase
AYN53_RS18570	COG3154	lipid carrier protein
AYN53_RS18575	COG0826	peptidase U32
AYN53_RS18580	COG0826	peptidase U32
AYN53_RS18585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AYN53_RS18590	COG3034	peptidoglycan biosynthetic process
AYN53_RS18600	COG0814	amino acid
AYN53_RS18605	COG0513	Belongs to the DEAD box helicase family
AYN53_RS18645	COG0195	Participates in both transcription termination and antitermination
AYN53_RS18670	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AYN53_RS18685	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AYN53_RS18690	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AYN53_RS18700	COG1534	Rna-binding protein
AYN53_RS18705	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AYN53_RS18710	COG2027	D-alanyl-D-alanine carboxypeptidase
AYN53_RS18720	COG0697	spore germination
AYN53_RS18735	COG0142	geranyltranstransferase activity
AYN53_RS18740	COG3423	Transcriptional regulator
AYN53_RS18750	COG5007	Belongs to the BolA IbaG family
AYN53_RS18755	COG3113	response to antibiotic
AYN53_RS18760	COG2854	intermembrane phospholipid transfer
AYN53_RS18765	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AYN53_RS18770	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AYN53_RS18775	COG1127	ABC transporter
AYN53_RS18780	COG0530	calcium, potassium:sodium antiporter activity
AYN53_RS18785	COG0517	IMP dehydrogenase activity
AYN53_RS18785	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AYN53_RS18790	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AYN53_RS18795	COG3117	lipopolysaccharide transmembrane transporter activity
AYN53_RS18800	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AYN53_RS18805	COG1137	ATPase activity
AYN53_RS18810	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AYN53_RS18815	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AYN53_RS18830	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN53_RS18835	COG0515	serine threonine protein kinase
AYN53_RS18845	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AYN53_RS18850	COG0784	Response regulator, receiver
AYN53_RS18850	COG2198	Histidine kinase
AYN53_RS18850	COG5002	protein histidine kinase activity
AYN53_RS18855	COG1242	4 iron, 4 sulfur cluster binding
AYN53_RS18870	COG0069	glutamate synthase activity
AYN53_RS18870	COG0067	glutamate synthase
AYN53_RS18870	COG0070	glutamate synthase
AYN53_RS18875	COG0493	'glutamate synthase
AYN53_RS18880	COG4804	nuclease activity
AYN53_RS18885	COG2731	YhcH YjgK YiaL family protein
AYN53_RS18915	COG2969	positive regulation of protein catabolic process
AYN53_RS18920	COG0625	glutathione transferase activity
AYN53_RS18945	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AYN53_RS18950	COG3105	Protein conserved in bacteria
AYN53_RS18955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AYN53_RS18960	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AYN53_RS18980	COG2732	(Barnase) inhibitor
AYN53_RS19000	COG0583	DNA-binding transcription factor activity
AYN53_RS19005	COG0312	modulator of DNA gyrase
AYN53_RS19010	COG3164	Protein of unknown function
AYN53_RS19015	COG1530	ribonuclease E activity
AYN53_RS19025	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AYN53_RS19030	COG1792	Involved in formation and maintenance of cell shape
AYN53_RS19035	COG1077	Cell shape determining protein MreB Mrl
AYN53_RS19050	COG2199	diguanylate cyclase activity
AYN53_RS19050	COG2200	EAL domain
AYN53_RS19055	COG0604	alcohol dehydrogenase
AYN53_RS19070	COG0511	ligase activity, forming carbon-carbon bonds
AYN53_RS19075	COG0439	Biotin carboxylase
AYN53_RS19080	COG3924	membrane
AYN53_RS19085	COG4145	pantothenate transmembrane transporter activity
AYN53_RS19095	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AYN53_RS19105	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AYN53_RS19115	COG1309	transcriptional regulator
AYN53_RS19125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYN53_RS19130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AYN53_RS19175	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AYN53_RS19195	COG0551	DNA topoisomerase type I activity
AYN53_RS19205	COG0758	DNA mediated transformation
AYN53_RS19225	COG0569	domain protein
AYN53_RS19235	COG3036	rescue of stalled ribosome
AYN53_RS19240	COG0789	Transcriptional regulator
AYN53_RS19280	COG0201	protein transport
AYN53_RS19370	COG0089	rRNA binding
AYN53_RS19455	COG2964	Protein conserved in bacteria
AYN53_RS19460	COG0545	Peptidyl-prolyl cis-trans isomerase
AYN53_RS19470	COG1047	Peptidyl-prolyl cis-trans
AYN53_RS19475	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AYN53_RS19495	COG0488	(ABC) transporter
AYN53_RS19500	COG0429	hydrolase of the alpha beta-hydrolase fold
AYN53_RS19510	COG3954	Phosphoribulokinase
AYN53_RS19515	COG1765	OsmC-like protein
AYN53_RS19525	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AYN53_RS19530	COG1289	transmembrane transporter activity
AYN53_RS19535	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AYN53_RS19540	COG0512	Glutamine amidotransferase of anthranilate synthase
AYN53_RS19545	COG2184	nucleotidyltransferase activity
AYN53_RS19555	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AYN53_RS19565	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AYN53_RS19570	COG2146	nitrite reductase [NAD(P)H] activity
AYN53_RS19575	COG2116	formate transmembrane transporter activity
AYN53_RS19590	COG0626	cystathionine gamma-synthase activity
AYN53_RS19605	COG1735	metal-dependent hydrolase with the TIM-barrel fold
AYN53_RS19610	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AYN53_RS19615	COG3457	Alanine racemase
AYN53_RS19625	COG2188	Transcriptional regulator
AYN53_RS19630	COG0180	Tryptophanyl-tRNA synthetase
AYN53_RS19640	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AYN53_RS19645	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AYN53_RS19650	COG3266	domain, Protein
AYN53_RS19665	COG4796	Type ii and iii secretion system protein
AYN53_RS19680	COG3166	PFAM Fimbrial assembly family protein
AYN53_RS19685	COG4972	Pilus assembly protein
AYN53_RS19690	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AYN53_RS19695	COG0494	nUDIX hydrolase
AYN53_RS19710	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AYN53_RS19750	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AYN53_RS19755	COG2183	response to ionizing radiation
AYN53_RS19765	COG1918	ferrous iron import across plasma membrane
AYN53_RS19770	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AYN53_RS19800	COG2610	gluconate transmembrane transporter activity
AYN53_RS19805	COG1640	4-alpha-glucanotransferase
AYN53_RS19830	COG1349	DNA-binding transcription factor activity
AYN53_RS19845	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AYN53_RS19885	COG0058	SHG alpha-glucan phosphorylase activity
AYN53_RS19910	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AYN53_RS19915	COG2095	MarC family integral membrane protein
AYN53_RS19920	COG2610	gluconate transmembrane transporter activity
AYN53_RS19925	COG3265	gluconokinase activity
AYN53_RS19930	COG1609	Transcriptional regulator
AYN53_RS19935	COG1741	Belongs to the pirin family
AYN53_RS19940	COG0673	inositol 2-dehydrogenase activity
AYN53_RS19950	COG1247	-acetyltransferase
AYN53_RS19955	COG0405	Gamma-glutamyltransferase
AYN53_RS19965	COG0584	glycerophosphoryl diester phosphodiesterase
AYN53_RS19995	COG0410	ABC transporter
AYN53_RS20005	COG4177	L-phenylalanine transmembrane transporter activity
AYN53_RS20010	COG0559	Belongs to the binding-protein-dependent transport system permease family
AYN53_RS20015	COG0683	leucine binding
AYN53_RS20020	COG0456	acetyltransferase
AYN53_RS20035	COG0683	leucine binding
AYN53_RS20045	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AYN53_RS20050	COG2177	Part of the ABC transporter FtsEX involved in
AYN53_RS20055	COG2884	Cell division ATP-binding protein ftsE
AYN53_RS20060	COG0552	protein localization to endoplasmic reticulum
AYN53_RS20065	COG0742	ribosomal rna small subunit methyltransferase
AYN53_RS20070	COG3776	membrane
AYN53_RS20080	COG3714	YhhN family
AYN53_RS20100	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AYN53_RS20110	COG0477	Major facilitator Superfamily
AYN53_RS20115	COG0628	permease
AYN53_RS20120	COG2091	lysine biosynthetic process via aminoadipic acid
AYN53_RS20125	COG0747	negative chemotaxis
AYN53_RS20130	COG0601	transmembrane transport
AYN53_RS20135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AYN53_RS20155	COG2188	Transcriptional regulator
AYN53_RS20165	COG3414	Phosphotransferase system galactitol-specific IIB component
AYN53_RS20170	COG3775	system Galactitol-specific IIC component
AYN53_RS20185	COG0191	fructose-bisphosphate aldolase activity
AYN53_RS20190	COG0842	Transport permease protein
AYN53_RS20195	COG1129	ABC transporter
AYN53_RS20195	COG0842	Transport permease protein
AYN53_RS20200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYN53_RS20215	COG4571	Outer membrane protease
AYN53_RS20225	COG2200	EAL domain
AYN53_RS20265	COG2081	HI0933 family
AYN53_RS20270	COG0306	phosphate transporter
AYN53_RS20280	COG0589	response to stress
AYN53_RS20295	COG3104	oligopeptide transport
AYN53_RS20305	COG0339	signal peptide processing
AYN53_RS20310	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AYN53_RS20315	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AYN53_RS20335	COG3549	Plasmid maintenance system killer
AYN53_RS20340	COG3093	addiction module antidote protein HigA
AYN53_RS20345	COG3065	identical protein binding
AYN53_RS20355	COG2197	response regulator
AYN53_RS20360	COG3720	iron ion transport
AYN53_RS20370	COG4558	Periplasmic binding protein
AYN53_RS20380	COG3721	Heme iron utilization protein
AYN53_RS20390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AYN53_RS20410	COG3247	response to pH
AYN53_RS20415	COG2771	luxR family
AYN53_RS20430	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AYN53_RS20440	COG2207	Transcriptional regulator
AYN53_RS20445	COG2207	Transcriptional regulator
AYN53_RS20450	COG0076	glutamate decarboxylase activity
AYN53_RS20455	COG1858	cytochrome C peroxidase
AYN53_RS20465	COG2197	response regulator
AYN53_RS20470	COG0583	DNA-binding transcription factor activity
AYN53_RS20475	COG1295	ribonuclease BN
AYN53_RS20480	COG0477	Major facilitator Superfamily
AYN53_RS20495	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AYN53_RS20500	COG0612	Peptidase, M16
AYN53_RS20515	COG2199	diguanylate cyclase activity
AYN53_RS20515	COG2200	EAL domain
AYN53_RS20520	COG0457	Tetratricopeptide repeat
AYN53_RS20520	COG3118	belongs to the thioredoxin family
AYN53_RS20525	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AYN53_RS20530	COG1215	transferase activity, transferring glycosyl groups
AYN53_RS20535	COG1215	transferase activity, transferring glycosyl groups
AYN53_RS20560	COG2194	sulfuric ester hydrolase activity
AYN53_RS20570	COG0814	amino acid
AYN53_RS20575	COG4608	Belongs to the ABC transporter superfamily
AYN53_RS20580	COG0444	Belongs to the ABC transporter superfamily
AYN53_RS20585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AYN53_RS20590	COG0601	transmembrane transport
AYN53_RS20600	COG0747	negative chemotaxis
AYN53_RS20625	COG2194	sulfuric ester hydrolase activity
AYN53_RS20630	COG2223	nitrite transmembrane transporter activity
AYN53_RS20640	COG5571	outer membrane autotransporter
AYN53_RS20645	COG2818	Glycosylase
AYN53_RS20650	COG0456	acetyltransferase
AYN53_RS20655	COG0243	molybdopterin cofactor binding
AYN53_RS20660	COG2885	chlorophyll binding
AYN53_RS20675	COG2944	sequence-specific DNA binding
AYN53_RS20680	COG1278	Cold shock
AYN53_RS20705	COG3274	enterobacterial common antigen metabolic process
AYN53_RS20710	COG4682	membrane
AYN53_RS20715	COG2992	FlgJ-related protein
AYN53_RS20730	COG3977	Valine--pyruvate aminotransferase
AYN53_RS20735	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AYN53_RS20740	COG1414	Transcriptional regulator
AYN53_RS20750	COG2731	YhcH YjgK YiaL family protein
AYN53_RS20755	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AYN53_RS20760	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AYN53_RS20765	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AYN53_RS20770	COG1070	Carbohydrate kinase
AYN53_RS20775	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AYN53_RS20780	COG3623	hexulose-6-phosphate isomerase
AYN53_RS20785	COG0235	Class ii aldolase
AYN53_RS20790	COG1012	belongs to the aldehyde dehydrogenase family
AYN53_RS20805	COG3276	selenocysteine insertion sequence binding
AYN53_RS20815	COG0625	glutathione transferase activity
AYN53_RS20820	COG2258	MOSC domain
AYN53_RS20825	COG1566	PFAM secretion protein HlyD family protein
AYN53_RS20835	COG2213	PTS system mannitol-specific
AYN53_RS20835	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN53_RS20845	COG3722	fumarate hydratase activity
AYN53_RS20865	COG1620	l-lactate permease
AYN53_RS20870	COG2186	Transcriptional regulator
AYN53_RS20880	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AYN53_RS20885	COG1045	serine acetyltransferase
AYN53_RS20900	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AYN53_RS20905	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AYN53_RS20920	COG4942	peptidase
AYN53_RS20925	COG2861	carbohydrate metabolic process
AYN53_RS20930	COG1216	Glycosyl transferase, family 2
AYN53_RS20940	COG0156	8-amino-7-oxononanoate synthase activity
AYN53_RS20950	COG0859	PFAM glycosyl transferase family 9
AYN53_RS20955	COG0859	PFAM glycosyl transferase family 9
AYN53_RS20975	COG3642	lipopolysaccharide core region biosynthetic process
AYN53_RS20980	COG1442	glycosyl transferase family 8
AYN53_RS20985	COG1442	glycosyl transferase family 8
AYN53_RS20990	COG0438	transferase activity, transferring glycosyl groups
AYN53_RS20995	COG0859	PFAM glycosyl transferase family 9
AYN53_RS21000	COG0515	serine threonine protein kinase
AYN53_RS21005	COG0438	transferase activity, transferring glycosyl groups
AYN53_RS21010	COG0859	PFAM glycosyl transferase family 9
AYN53_RS21015	COG1519	Transferase
AYN53_RS21045	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AYN53_RS21070	COG1561	YicC-like family, N-terminal region
AYN53_RS21190	COG3710	Transcriptional regulator
AYN53_RS21195	COG0531	amino acid
AYN53_RS21200	COG1982	Orn Lys Arg decarboxylase major
AYN53_RS21205	COG3104	oligopeptide transport
AYN53_RS21210	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AYN53_RS21215	COG2860	membrane
AYN53_RS21230	COG0194	GDP metabolic process
AYN53_RS21240	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AYN53_RS21245	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AYN53_RS21250	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AYN53_RS21255	COG0786	glutamate:sodium symporter activity
AYN53_RS21260	COG2233	PERMEase
AYN53_RS21265	COG2982	Protein involved in outer membrane biogenesis
AYN53_RS21275	COG0582	viral genome integration into host DNA
AYN53_RS21360	COG2814	Major facilitator Superfamily
AYN53_RS21370	COG0697	spore germination
AYN53_RS21380	COG0457	Tetratricopeptide repeat
AYN53_RS21415	COG1470	cell adhesion involved in biofilm formation
AYN53_RS21415	COG1388	LysM domain
AYN53_RS21425	COG2252	PERMEase
AYN53_RS21435	COG2271	Major facilitator Superfamily
AYN53_RS21445	COG3851	Histidine kinase
AYN53_RS21450	COG2197	response regulator
AYN53_RS21455	COG0440	acetolactate synthase activity
AYN53_RS21460	COG0028	Belongs to the TPP enzyme family
AYN53_RS21470	COG2814	Major facilitator Superfamily
AYN53_RS21475	COG0641	radical SAM
AYN53_RS21485	COG2149	membrane
AYN53_RS21495	COG3119	arylsulfatase activity
AYN53_RS21505	COG2207	Transcriptional regulator
AYN53_RS21520	COG2188	Transcriptional regulator
AYN53_RS21540	COG5645	(Lipo)protein
AYN53_RS21545	COG0823	Involved in the tonB-independent uptake of proteins
AYN53_RS21560	COG0561	phosphatase activity
AYN53_RS21565	COG3753	Protein conserved in bacteria
AYN53_RS21570	COG0187	DNA topoisomerase II activity
AYN53_RS21580	COG0592	DNA-directed DNA polymerase activity
AYN53_RS21630	COG0814	amino acid
AYN53_RS21645	COG2091	lysine biosynthetic process via aminoadipic acid
AYN53_RS21660	COG0431	NADPH-dependent FMN reductase
AYN53_RS21665	COG2204	response regulator
AYN53_RS21675	COG1053	succinate dehydrogenase
AYN53_RS21675	COG3976	FMN-binding domain protein
AYN53_RS21690	COG2252	PERMEase
AYN53_RS21695	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AYN53_RS21735	COG0704	Plays a role in the regulation of phosphate uptake
AYN53_RS21740	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AYN53_RS21745	COG0581	inorganic phosphate transmembrane transporter activity
AYN53_RS21750	COG0573	inorganic phosphate transmembrane transporter activity
AYN53_RS21755	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AYN53_RS21800	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AYN53_RS21815	COG3312	ion transport
AYN53_RS21835	COG0716	FMN binding
AYN53_RS21840	COG1522	sequence-specific DNA binding
AYN53_RS21870	COG1129	ABC transporter
AYN53_RS21875	COG1172	Belongs to the binding-protein-dependent transport system permease family
AYN53_RS21880	COG1879	ABC-type sugar transport system periplasmic component
AYN53_RS21885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AYN53_RS21890	COG1609	Transcriptional regulator
AYN53_RS21895	COG0477	Major facilitator Superfamily
AYN53_RS21900	COG2186	Transcriptional regulator
AYN53_RS21940	COG3085	chromosome segregation
AYN53_RS21945	COG0606	chelatase, subunit chli
AYN53_RS21970	COG3978	acetolactate synthase activity
AYN53_RS21975	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AYN53_RS21985	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AYN53_RS22000	COG0583	DNA-binding transcription factor activity
AYN53_RS22010	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AYN53_RS22015	COG0210	DNA helicase
AYN53_RS22035	COG3118	belongs to the thioredoxin family
AYN53_RS22045	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AYN53_RS22050	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AYN53_RS22055	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
AYN53_RS22060	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AYN53_RS22065	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AYN53_RS22070	COG1088	dTDP-glucose 4,6-dehydratase activity
AYN53_RS22075	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AYN53_RS22080	COG0456	acetyltransferase
AYN53_RS22085	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AYN53_RS22090	COG2244	polysaccharide biosynthetic process
AYN53_RS22110	COG1113	amino acid transport
AYN53_RS22135	COG0641	radical SAM
AYN53_RS22140	COG3119	arylsulfatase activity
AYN53_RS22145	COG3071	HemY protein
AYN53_RS22150	COG2959	enzyme of heme biosynthesis
AYN53_RS22155	COG1587	Uroporphyrinogen-III synthase
AYN53_RS22170	COG3072	Adenylate cyclase
AYN53_RS22185	COG5567	small periplasmic lipoprotein
AYN53_RS22195	COG3159	Protein conserved in bacteria
AYN53_RS22205	COG1011	Hydrolase
AYN53_RS22210	COG0210	DNA helicase
AYN53_RS22215	COG3698	Phosphodiester glycosidase
AYN53_RS22220	COG0598	Magnesium transport protein CorA
AYN53_RS22235	COG2962	Rard protein
AYN53_RS22240	COG2050	protein possibly involved in aromatic compounds catabolism
AYN53_RS22245	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
AYN53_RS22250	COG0514	ATP-dependent DNA helicase (RecQ)
AYN53_RS22255	COG1280	lysine exporter protein (LysE YggA)
AYN53_RS22265	COG2267	carboxylic ester hydrolase activity
AYN53_RS22270	COG0561	phosphatase activity
AYN53_RS22275	COG0697	spore germination
AYN53_RS22280	COG0583	DNA-binding transcription factor activity
AYN53_RS22290	COG0412	Dienelactone hydrolase
AYN53_RS22295	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
AYN53_RS22315	COG0800	Aldolase
AYN53_RS22320	COG3734	2-keto-3-deoxy-galactonokinase
AYN53_RS22325	COG1414	Transcriptional regulator
AYN53_RS22330	COG1322	Protein conserved in bacteria
AYN53_RS22340	COG3165	ubiquinone biosynthetic process from chorismate
AYN53_RS22350	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AYN53_RS22360	COG0805	protein transport
AYN53_RS22380	COG0543	2 iron, 2 sulfur cluster binding
AYN53_RS22400	COG1739	Uncharacterized protein family UPF0029
AYN53_RS22405	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AYN53_RS22410	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
AYN53_RS22435	COG1763	Mo-molybdopterin cofactor biosynthetic process
AYN53_RS22440	COG0746	molybdenum cofactor guanylyltransferase activity
AYN53_RS22445	COG3084	Protein conserved in bacteria
AYN53_RS22450	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AYN53_RS22455	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AYN53_RS22460	COG5339	Protein conserved in bacteria
AYN53_RS22465	COG0204	Acyl-transferase
AYN53_RS22475	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AYN53_RS22475	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AYN53_RS22490	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AYN53_RS22500	COG2204	response regulator
AYN53_RS22505	COG3852	Histidine kinase
AYN53_RS22510	COG0174	glutamine synthetase
AYN53_RS22520	COG1217	gtp-binding protein TYPA
AYN53_RS22525	COG2188	Transcriptional regulator
AYN53_RS22530	COG1082	Xylose isomerase domain protein TIM barrel
AYN53_RS22535	COG2271	Major facilitator Superfamily
AYN53_RS22540	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AYN53_RS22545	COG2211	Major facilitator Superfamily
AYN53_RS22550	COG2211	Major facilitator Superfamily
AYN53_RS22555	COG1501	Belongs to the glycosyl hydrolase 31 family
AYN53_RS22560	COG2017	converts alpha-aldose to the beta-anomer
AYN53_RS22565	COG2942	2-epimerase
AYN53_RS22570	COG3684	Belongs to the aldolase LacD family
AYN53_RS22575	COG2084	Dehydrogenase
AYN53_RS22580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AYN53_RS22585	COG1349	DNA-binding transcription factor activity
AYN53_RS22590	COG1011	Hydrolase
AYN53_RS22605	COG0456	acetyltransferase
AYN53_RS22635	COG2864	formate dehydrogenase
AYN53_RS22640	COG0437	4 iron, 4 sulfur cluster binding
AYN53_RS22670	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AYN53_RS22675	COG2258	MOSC domain
AYN53_RS22680	COG2205	protein histidine kinase activity
AYN53_RS22685	COG0745	RESPONSE REGULATOR receiver
AYN53_RS22690	COG3678	ATP-independent chaperone mediated protein folding
AYN53_RS22705	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AYN53_RS22725	COG3152	Membrane
AYN53_RS22730	COG3691	Protein conserved in bacteria
AYN53_RS22735	COG0589	response to stress
AYN53_RS22745	COG1494	fructose-1,6-bisphosphatase
AYN53_RS22755	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AYN53_RS22780	COG1575	Belongs to the MenA family. Type 1 subfamily
AYN53_RS22795	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AYN53_RS22800	COG1609	Transcriptional regulator
AYN53_RS22805	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AYN53_RS22815	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
AYN53_RS22825	COG0626	cystathionine gamma-synthase activity
AYN53_RS22830	COG0527	aspartate kinase activity
AYN53_RS22830	COG0460	homoserine dehydrogenase
AYN53_RS22840	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AYN53_RS22850	COG0697	spore germination
AYN53_RS22855	COG3738	Protein conserved in bacteria
AYN53_RS22860	COG0371	Dehydrogenase
AYN53_RS22865	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AYN53_RS22875	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AYN53_RS22880	COG1882	Formate acetyltransferase
AYN53_RS22890	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AYN53_RS22895	COG2207	Transcriptional regulator
AYN53_RS22900	COG2194	sulfuric ester hydrolase activity
AYN53_RS22915	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AYN53_RS22930	COG0583	DNA-binding transcription factor activity
AYN53_RS22940	COG1473	amidohydrolase
AYN53_RS22945	COG0477	Major facilitator Superfamily
AYN53_RS22965	COG4206	TonB-dependent receptor
AYN53_RS23000	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AYN53_RS23005	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AYN53_RS23005	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AYN53_RS23045	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AYN53_RS23050	COG0250	Participates in transcription elongation, termination and antitermination
AYN53_RS23090	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AYN53_RS23100	COG2104	thiamine diphosphate biosynthetic process
AYN53_RS23105	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AYN53_RS23140	COG3068	Protein conserved in bacteria
AYN53_RS23155	COG3678	ATP-independent chaperone mediated protein folding
AYN53_RS23165	COG4191	Histidine kinase
AYN53_RS23170	COG2204	response regulator
AYN53_RS23175	COG0151	Belongs to the GarS family
AYN53_RS23210	COG0456	acetyltransferase
AYN53_RS23220	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AYN53_RS23225	COG2224	Isocitrate lyase
AYN53_RS23235	COG1414	Transcriptional regulator
AYN53_RS23240	COG1410	methionine synthase
AYN53_RS23240	COG0646	methionine synthase
AYN53_RS23245	COG1283	sodium-dependent phosphate transmembrane transporter activity
AYN53_RS23255	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AYN53_RS23295	COG1187	pseudouridine synthase activity
AYN53_RS23305	COG0527	aspartate kinase activity
AYN53_RS23335	COG3833	ABC-type maltose transport systems, permease component
AYN53_RS23340	COG1175	transmembrane transport
AYN53_RS23355	COG3842	ATPase activity
AYN53_RS23385	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AYN53_RS23395	COG0534	Mate efflux family protein
AYN53_RS23400	COG3237	CsbD-like
AYN53_RS23405	COG0735	belongs to the Fur family
AYN53_RS23410	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AYN53_RS23420	COG0604	alcohol dehydrogenase
AYN53_RS23425	COG0305	Participates in initiation and elongation during chromosome replication
AYN53_RS23435	COG1448	Aminotransferase
AYN53_RS23440	COG0567	Dehydrogenase, E1 component
AYN53_RS23450	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AYN53_RS23455	COG0045	succinate-CoA ligase (ADP-forming) activity
AYN53_RS23460	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AYN53_RS23470	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AYN53_RS23485	COG3700	Belongs to the class B bacterial acid phosphatase family
AYN53_RS23490	COG0432	Pfam Uncharacterised protein family UPF0047
AYN53_RS23495	COG2315	Protein conserved in bacteria
AYN53_RS23500	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AYN53_RS23505	COG0629	single-stranded DNA binding
AYN53_RS23520	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AYN53_RS23525	COG2207	Transcriptional regulator
AYN53_RS23530	COG0789	Transcriptional regulator
AYN53_RS23550	COG2252	PERMEase
AYN53_RS23555	COG0025	NhaP-type Na H and K H
AYN53_RS23565	COG3162	membrane
AYN53_RS23570	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AYN53_RS23590	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
AYN53_RS23595	COG0437	4 iron, 4 sulfur cluster binding
AYN53_RS23600	COG3301	Polysulphide reductase, NrfD
AYN53_RS23610	COG3088	subunit of a heme lyase
AYN53_RS23615	COG4235	cytochrome complex assembly
AYN53_RS23625	COG1301	dicarboxylic acid transport
AYN53_RS23635	COG4608	Belongs to the ABC transporter superfamily
AYN53_RS23640	COG0444	Belongs to the ABC transporter superfamily
AYN53_RS23645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AYN53_RS23650	COG0601	transmembrane transport
AYN53_RS23670	COG1289	transmembrane transporter activity
AYN53_RS23675	COG1566	PFAM secretion protein HlyD family protein
AYN53_RS23695	COG1028	Short-chain dehydrogenase reductase Sdr
AYN53_RS23700	COG1024	Enoyl-CoA hydratase
AYN53_RS23705	COG0477	Major facilitator Superfamily
AYN53_RS23710	COG4670	ketone body catabolic process
AYN53_RS23730	COG1028	Short-chain dehydrogenase reductase Sdr
AYN53_RS23755	COG2764	glyoxalase bleomycin resistance protein dioxygenase
AYN53_RS23760	COG2824	Alkylphosphonate utilization operon protein PhnA
AYN53_RS23785	COG0642	Histidine kinase
AYN53_RS23790	COG0745	RESPONSE REGULATOR receiver
AYN53_RS23795	COG2194	sulfuric ester hydrolase activity
AYN53_RS23800	COG0531	amino acid
AYN53_RS23805	COG2207	Transcriptional regulator
AYN53_RS23810	COG1982	Orn Lys Arg decarboxylase major
AYN53_RS23815	COG3647	Membrane
AYN53_RS23820	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AYN53_RS23820	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AYN53_RS23825	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AYN53_RS23835	COG4565	transcriptional regulatory protein
AYN53_RS23840	COG3290	protein histidine kinase activity
AYN53_RS23845	COG3592	Divergent 4Fe-4S mono-cluster
AYN53_RS23850	COG2388	GCN5-related N-acetyl-transferase
AYN53_RS24105	COG1309	transcriptional regulator
AYN53_RS24110	COG4232	protein-disulfide reductase activity
AYN53_RS24120	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AYN53_RS24125	COG1027	Aspartate ammonia-lyase
AYN53_RS24130	COG3030	protein affecting phage T7 exclusion by the F plasmid
AYN53_RS24160	COG1509	lysine 2,3-aminomutase activity
AYN53_RS24170	COG5510	response to toxic substance
AYN53_RS24180	COG2076	Multidrug Resistance protein
AYN53_RS24185	COG3040	lipid binding
AYN53_RS24190	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AYN53_RS24205	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AYN53_RS24210	COG1053	succinate dehydrogenase
AYN53_RS24220	COG0531	amino acid
AYN53_RS24235	COG3264	Mechanosensitive ion channel
AYN53_RS24235	COG1511	domain protein
AYN53_RS24270	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AYN53_RS24275	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AYN53_RS24275	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AYN53_RS24280	COG0802	atpase or kinase
AYN53_RS24285	COG0860	N-Acetylmuramoyl-L-alanine amidase
AYN53_RS24290	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AYN53_RS24305	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AYN53_RS24310	COG0330	HflC and HflK could
AYN53_RS24315	COG0330	HflC and HflK could
AYN53_RS24320	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AYN53_RS24335	COG0557	exoribonuclease II activity
AYN53_RS24340	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AYN53_RS24345	COG0754	glutathionylspermidine amidase activity
AYN53_RS24350	COG1960	acyl-CoA dehydrogenase activity
AYN53_RS24360	COG3650	response to hydrogen peroxide
AYN53_RS24365	COG1073	alpha beta
AYN53_RS24380	COG3037	sugar-specific permease SgaT UlaA
AYN53_RS24385	COG3414	Phosphotransferase system galactitol-specific IIB component
AYN53_RS24390	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN53_RS24410	COG3477	response to acidic pH
AYN53_RS24430	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AYN53_RS24440	COG2271	Major facilitator Superfamily
AYN53_RS24445	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AYN53_RS24450	COG4670	ketone body catabolic process
AYN53_RS24455	COG1024	Enoyl-CoA hydratase
AYN53_RS24470	COG1309	transcriptional regulator
AYN53_RS24475	COG3061	Opacity-associated protein A
AYN53_RS24485	COG0545	Peptidyl-prolyl cis-trans isomerase
AYN53_RS24490	COG1113	amino acid transport
AYN53_RS24510	COG0697	spore germination
AYN53_RS24515	COG1733	regulation of RNA biosynthetic process
AYN53_RS24520	COG0737	Belongs to the 5'-nucleotidase family
AYN53_RS24525	COG1218	3'(2'),5'-bisphosphate nucleotidase
AYN53_RS24535	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AYN53_RS24545	COG1253	flavin adenine dinucleotide binding
AYN53_RS24560	COG0729	surface antigen
AYN53_RS24565	COG2911	Protein conserved in bacteria
AYN53_RS24570	COG2105	PFAM AIG2 family protein
AYN53_RS24575	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AYN53_RS24580	COG1879	ABC-type sugar transport system periplasmic component
AYN53_RS24590	COG1129	ABC transporter
AYN53_RS24595	COG1172	Belongs to the binding-protein-dependent transport system permease family
AYN53_RS24600	COG1172	Belongs to the binding-protein-dependent transport system permease family
AYN53_RS24620	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AYN53_RS24630	COG0312	modulator of DNA gyrase
AYN53_RS24635	COG3783	Cytochrome b(562)
AYN53_RS24645	COG2026	Addiction module toxin, RelE StbE family
AYN53_RS24650	COG0602	queuosine metabolic process
AYN53_RS24655	COG1328	CTP reductase activity
AYN53_RS24680	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AYN53_RS24690	COG0251	oxidation-reduction process
AYN53_RS24710	COG2731	YhcH YjgK YiaL family protein
AYN53_RS24730	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
AYN53_RS24735	COG0456	acetyltransferase
AYN53_RS24745	COG0525	valine-tRNA ligase activity
AYN53_RS24750	COG2927	DNA polymerase III (CHI subunit)
AYN53_RS24760	COG0795	lipopolysaccharide-transporting ATPase activity
AYN53_RS24765	COG0795	lipopolysaccharide-transporting ATPase activity
AYN53_RS24770	COG0433	COG0433 Predicted ATPase
AYN53_RS24775	COG1064	alcohol dehydrogenase
AYN53_RS24845	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
AYN53_RS24855	COG0582	viral genome integration into host DNA
AYN53_RS24860	COG4974	Belongs to the 'phage' integrase family
AYN53_RS24870	COG3539	Fimbrial protein
AYN53_RS24875	COG3121	Chaperone
AYN53_RS24935	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AYN53_RS24970	COG0305	Participates in initiation and elongation during chromosome replication
AYN53_RS25215	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AYN53_RS25300	COG0371	Dehydrogenase
AYN53_RS25335	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AYN53_RS25385	COG0741	lytic transglycosylase activity
AYN53_RS25500	COG1475	DNA binding
AYN53_RS26090	COG1294	oxidase, subunit
AYN53_RS26095	COG1271	oxidase subunit
AYN53_RS26110	COG3220	belongs to the UPF0276 family
AYN53_RS26145	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AYN53_RS26165	COG3290	protein histidine kinase activity
AYN53_RS26165	COG3829	transcription factor binding
AYN53_RS26180	COG2721	sulfolactate sulfo-lyase activity
AYN53_RS26200	COG0726	polysaccharide deacetylase
AYN53_RS26205	COG0297	glycogen (starch) synthase activity
AYN53_RS26210	COG1560	Kdo2-lipid A biosynthetic process
AYN53_RS26215	COG2990	Protein conserved in bacteria
AYN53_RS26225	COG1116	anion transmembrane transporter activity
AYN53_RS26475	COG3121	Chaperone
AYN53_RS26485	COG3188	usher protein
AYN53_RS26490	COG3121	Chaperone
AYN53_RS26500	COG1278	Cold shock
AYN53_RS26515	COG1252	NADH dehydrogenase
AYN53_RS26575	COG2771	luxR family
AYN53_RS26575	COG2200	EAL domain