locus-tag	class	description
AYN53_RS00005	COG3188	usher protein
AYN53_RS00010	COG3539	Fimbrial protein
AYN53_RS00015	COG3539	Fimbrial protein
AYN53_RS00020	COG3539	Fimbrial protein
AYN53_RS00025	COG2610	gluconate transmembrane transporter activity
AYN53_RS00035	COG0246	Mannitol dehydrogenase
AYN53_RS00040	COG2186	Transcriptional regulator
AYN53_RS00055	COG3518	anti-sigma factor antagonist activity
AYN53_RS00060	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AYN53_RS00065	COG0700	Nucleoside recognition
AYN53_RS00070	COG3366	ferrous iron transmembrane transporter activity
AYN53_RS00085	COG1924	4 iron, 4 sulfur cluster binding
AYN53_RS00090	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
AYN53_RS00095	COG2733	membrane
AYN53_RS00120	COG1401	restriction endodeoxyribonuclease activity
AYN53_RS00135	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AYN53_RS00140	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
AYN53_RS00145	COG1715	Restriction endonuclease
AYN53_RS00150	COG0523	cobalamin synthesis protein
AYN53_RS00155	COG2879	small protein
AYN53_RS00160	COG1966	Carbon starvation protein
AYN53_RS00175	COG2271	Major facilitator Superfamily
AYN53_RS00180	COG1802	Transcriptional regulator
AYN53_RS00185	COG1063	alcohol dehydrogenase
AYN53_RS00200	COG1484	DNA-dependent DNA replication
AYN53_RS00215	COG2966	Psort location CytoplasmicMembrane, score
AYN53_RS00235	COG2197	response regulator
AYN53_RS00240	COG4114	ferric iron reductase
AYN53_RS00270	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
AYN53_RS00275	COG0456	acetyltransferase
AYN53_RS00280	COG1011	Hydrolase
AYN53_RS00285	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AYN53_RS00325	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AYN53_RS00330	COG5532	Uncharacterized conserved protein (DUF2303)
AYN53_RS00345	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AYN53_RS00350	COG4197	protein conserved in bacteria, prophage-related
AYN53_RS00365	COG1846	Transcriptional regulator
AYN53_RS00375	COG4725	Belongs to the MT-A70-like family
AYN53_RS00380	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
AYN53_RS00390	COG1403	HNH endonuclease
AYN53_RS00395	COG0484	heat shock protein binding
AYN53_RS00400	COG1278	Cold shock
AYN53_RS00410	COG3772	lysozyme
AYN53_RS00420	COG3646	Phage regulatory protein
AYN53_RS00525	COG5301	cellulose 1,4-beta-cellobiosidase activity
AYN53_RS00525	COG5301	cellulose 1,4-beta-cellobiosidase activity
AYN53_RS00525	COG5301	cellulose 1,4-beta-cellobiosidase activity
AYN53_RS00530	COG0727	PFAM Uncharacterised protein family (UPF0153)
AYN53_RS00550	COG2823	Periplasmic or secreted lipoprotein
AYN53_RS00560	COG4667	esterase of the alpha-beta hydrolase superfamily
AYN53_RS00565	COG0084	hydrolase, TatD family'
AYN53_RS00570	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AYN53_RS00575	COG1328	CTP reductase activity
AYN53_RS00600	COG0095	Lipoate-protein ligase
AYN53_RS00605	COG3726	membrane protein affecting hemolysin expression
AYN53_RS00610	COG0560	Phosphoserine phosphatase
AYN53_RS00615	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AYN53_RS00620	COG1056	cytidyltransferase-related domain
AYN53_RS00620	COG3172	ATPase kinase involved in NAD metabolism
AYN53_RS00625	COG0488	(ABC) transporter
AYN53_RS00630	COG0741	lytic transglycosylase activity
AYN53_RS00650	COG2207	Transcriptional regulator
AYN53_RS00650	COG3708	Transcriptional regulator
AYN53_RS00655	COG3045	CreA protein
AYN53_RS00660	COG0745	RESPONSE REGULATOR receiver
AYN53_RS00665	COG2205	protein histidine kinase activity
AYN53_RS00670	COG4452	Inner membrane protein CreD
AYN53_RS00675	COG0745	RESPONSE REGULATOR receiver
AYN53_RS00685	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AYN53_RS00695	COG0527	aspartate kinase activity
AYN53_RS00695	COG0460	homoserine dehydrogenase
AYN53_RS00705	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AYN53_RS00720	COG1115	amino acid carrier protein
AYN53_RS00730	COG0521	Mo-molybdopterin cofactor biosynthetic process
AYN53_RS00735	COG1584	GPR1 FUN34 yaaH family protein
AYN53_RS00775	COG3119	arylsulfatase activity
AYN53_RS00785	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AYN53_RS00790	COG0583	DNA-binding transcription factor activity
AYN53_RS00810	COG0196	riboflavin kinase activity
AYN53_RS00825	COG1047	Peptidyl-prolyl cis-trans
AYN53_RS00850	COG0505	Belongs to the CarA family
AYN53_RS00855	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AYN53_RS00905	COG0644	oxidoreductase
AYN53_RS00910	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AYN53_RS00915	COG2271	Major facilitator Superfamily
AYN53_RS00930	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AYN53_RS00965	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AYN53_RS00975	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AYN53_RS00980	COG0564	pseudouridine synthase activity
AYN53_RS00990	COG0417	DNA replication proofreading
AYN53_RS00995	COG0235	Class ii aldolase
AYN53_RS01010	COG4977	sequence-specific DNA binding
AYN53_RS01015	COG0586	Pfam SNARE associated Golgi protein
AYN53_RS01025	COG1178	ABC-type Fe3 transport system permease component
AYN53_RS01030	COG4143	(ABC) transporter
AYN53_RS01070	COG0583	DNA-binding transcription factor activity
AYN53_RS01075	COG0028	Belongs to the TPP enzyme family
AYN53_RS01080	COG0440	acetolactate synthase activity
AYN53_RS01090	COG1609	Transcriptional regulator
AYN53_RS01105	COG3116	cell division
AYN53_RS01110	COG0768	penicillin binding
AYN53_RS01115	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AYN53_RS01120	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AYN53_RS01135	COG0772	Belongs to the SEDS family
AYN53_RS01150	COG1181	Belongs to the D-alanine--D-alanine ligase family
AYN53_RS01155	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AYN53_RS01160	COG0849	cell division
AYN53_RS01165	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AYN53_RS01185	COG0494	nUDIX hydrolase
AYN53_RS01200	COG0237	dephospho-CoA kinase activity
AYN53_RS01215	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AYN53_RS01220	COG4969	Belongs to the N-Me-Phe pilin family
AYN53_RS01225	COG0157	Belongs to the NadC ModD family
AYN53_RS01230	COG3023	N-Acetylmuramoyl-L-alanine amidase
AYN53_RS01235	COG3725	Membrane protein required for beta-lactamase induction
AYN53_RS01240	COG1113	amino acid transport
AYN53_RS01245	COG2186	Transcriptional regulator
AYN53_RS01250	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AYN53_RS01255	COG0508	dehydrogenase complex catalyzes the overall conversion of
AYN53_RS01260	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AYN53_RS01270	COG3064	Membrane
AYN53_RS01275	COG1049	propionate catabolic process, 2-methylcitrate cycle
AYN53_RS01310	COG2132	Multicopper oxidase
AYN53_RS01325	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AYN53_RS01330	COG0288	reversible hydration of carbon dioxide
AYN53_RS01335	COG1131	(ABC) transporter
AYN53_RS01340	COG0842	Transport permease protein
AYN53_RS01345	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN53_RS01350	COG0726	polysaccharide deacetylase
AYN53_RS01360	COG5464	transposase or invertase
AYN53_RS01365	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AYN53_RS01380	COG3539	Fimbrial protein
AYN53_RS01390	COG3539	Fimbrial protein
AYN53_RS01400	COG3121	Chaperone
AYN53_RS01405	COG3539	Fimbrial protein
AYN53_RS01410	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AYN53_RS01415	COG0617	tRNA 3'-terminal CCA addition
AYN53_RS01425	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AYN53_RS01435	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AYN53_RS01440	COG1643	Atp-dependent helicase
AYN53_RS01445	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AYN53_RS01450	COG3853	Toxic anion resistance protein (TelA)
AYN53_RS01460	COG4774	siderophore transport
AYN53_RS01465	COG1120	ATPase activity
AYN53_RS01470	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AYN53_RS01475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AYN53_RS01500	COG2860	membrane
AYN53_RS01505	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AYN53_RS01520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AYN53_RS01525	COG3835	regulator
AYN53_RS01535	COG1408	metallophosphoesterase
AYN53_RS01550	COG0024	Methionine aminopeptidase
AYN53_RS01575	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AYN53_RS01580	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AYN53_RS01585	COG0575	Belongs to the CDS family
AYN53_RS01590	COG0750	zinc metalloprotease
AYN53_RS01600	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AYN53_RS01605	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AYN53_RS01630	COG0587	DNA-directed DNA polymerase activity
AYN53_RS01645	COG0346	lactoylglutathione lyase activity
AYN53_RS01650	COG0037	tRNA processing
AYN53_RS01655	COG4568	rho-dependent transcription termination
AYN53_RS01665	COG4681	YaeQ
AYN53_RS01670	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AYN53_RS01675	COG3015	lipoprotein NlpE involved in copper resistance
AYN53_RS01685	COG1720	tRNA m6t6A37 methyltransferase activity
AYN53_RS01695	COG1464	Belongs to the NlpA lipoprotein family
AYN53_RS01700	COG2011	ABC-type metal ion transport system permease component
AYN53_RS01710	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AYN53_RS01745	COG0656	L-ascorbic acid biosynthetic process
AYN53_RS01750	COG0583	DNA-binding transcription factor activity
AYN53_RS01760	COG0741	lytic transglycosylase activity
AYN53_RS01760	COG1388	LysM domain
AYN53_RS01765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AYN53_RS01770	COG2226	methyltransferase
AYN53_RS01780	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AYN53_RS01800	COG4104	PAAR repeat-containing protein
AYN53_RS01830	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AYN53_RS01840	COG1960	acyl-CoA dehydrogenase activity
AYN53_RS01850	COG0121	glutamine amidotransferase
AYN53_RS01855	COG3034	peptidoglycan biosynthetic process
AYN53_RS01860	COG0791	NLP P60 protein
AYN53_RS01870	COG1943	Transposase
AYN53_RS01890	COG2161	toxin-antitoxin pair type II binding
AYN53_RS01900	COG0454	-acetyltransferase
AYN53_RS01905	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AYN53_RS01920	COG2195	Cleaves the N-terminal amino acid of tripeptides
AYN53_RS01940	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AYN53_RS01960	COG0582	viral genome integration into host DNA
AYN53_RS02130	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AYN53_RS02170	COG3646	Phage regulatory protein
AYN53_RS02180	COG4220	transposase activity
AYN53_RS02200	COG1030	water channel activity
AYN53_RS02250	COG1196	nuclear chromosome segregation
AYN53_RS02280	COG5301	cellulose 1,4-beta-cellobiosidase activity
AYN53_RS02340	COG0500	methyltransferase
AYN53_RS02385	COG3059	membrane
AYN53_RS02395	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AYN53_RS02400	COG2207	Transcriptional regulator
AYN53_RS02405	COG1620	l-lactate permease
AYN53_RS02410	COG0247	lactate metabolic process
AYN53_RS02415	COG1139	Iron-sulfur cluster binding protein
AYN53_RS02420	COG1556	Lactate utilization protein
AYN53_RS02430	COG0667	Aldo Keto reductase
AYN53_RS02440	COG2200	EAL domain
AYN53_RS02440	COG2771	luxR family
AYN53_RS02445	COG0583	DNA-binding transcription factor activity
AYN53_RS02455	COG0666	response to abiotic stimulus
AYN53_RS02465	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AYN53_RS02470	COG1304	FMN binding
AYN53_RS02480	COG0549	Belongs to the carbamate kinase family
AYN53_RS02485	COG0402	S-adenosylhomocysteine deaminase activity
AYN53_RS02490	COG1280	lysine exporter protein (LysE YggA)
AYN53_RS02505	COG3829	transcription factor binding
AYN53_RS02510	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AYN53_RS02520	COG0372	Belongs to the citrate synthase family
AYN53_RS02525	COG2079	MmgE PrpD family protein
AYN53_RS02530	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AYN53_RS02540	COG3122	Protein conserved in bacteria
AYN53_RS02560	COG4521	taurine ABC transporter
AYN53_RS02570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AYN53_RS02575	COG2175	clavaminate synthase activity
AYN53_RS02580	COG0113	porphobilinogen synthase activity
AYN53_RS02585	COG3468	outer membrane autotransporter barrel domain protein
AYN53_RS02590	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AYN53_RS02595	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AYN53_RS02600	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AYN53_RS02620	COG1181	Belongs to the D-alanine--D-alanine ligase family
AYN53_RS02645	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AYN53_RS02660	COG4126	flavin adenine dinucleotide binding
AYN53_RS02680	COG1940	carbohydrate kinase activity
AYN53_RS02685	COG0419	ATPase involved in DNA repair
AYN53_RS02690	COG0420	3'-5' exonuclease activity
AYN53_RS02695	COG0745	RESPONSE REGULATOR receiver
AYN53_RS02700	COG5002	protein histidine kinase activity
AYN53_RS02705	COG1114	Component of the transport system for branched-chain amino acids
AYN53_RS02710	COG1113	amino acid transport
AYN53_RS02715	COG0366	Alpha amylase catalytic
AYN53_RS02735	COG1862	Preprotein translocase
AYN53_RS02740	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AYN53_RS02745	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AYN53_RS02750	COG1403	HNH endonuclease
AYN53_RS02755	COG3248	Nucleoside-binding outer membrane protein
AYN53_RS02760	COG4238	major outer membrane lipoprotein
AYN53_RS02770	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AYN53_RS02770	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AYN53_RS02785	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AYN53_RS02790	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AYN53_RS02800	COG0667	Aldo Keto reductase
AYN53_RS02810	COG0142	geranyltranstransferase activity
AYN53_RS02825	COG0693	protein deglycase activity
AYN53_RS02830	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AYN53_RS02840	COG2814	Major facilitator Superfamily
AYN53_RS02860	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AYN53_RS02865	COG1845	cytochrome c oxidase, subunit III
AYN53_RS02870	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AYN53_RS02875	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AYN53_RS02880	COG2223	nitrite transmembrane transporter activity
AYN53_RS02885	COG3056	Lipoprotein
AYN53_RS02890	COG0271	Belongs to the BolA IbaG family
AYN53_RS02910	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AYN53_RS02915	COG0776	regulation of translation
AYN53_RS02920	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AYN53_RS02925	COG1555	photosystem II stabilization
AYN53_RS02930	COG0824	Thioesterase
AYN53_RS02940	COG4533	DNA binding
AYN53_RS02950	COG1522	sequence-specific DNA binding
AYN53_RS02955	COG1132	(ABC) transporter
AYN53_RS02960	COG1132	(ABC) transporter
AYN53_RS02965	COG0347	Belongs to the P(II) protein family
AYN53_RS02970	COG0004	ammonium transporteR
AYN53_RS02975	COG1946	Acyl-CoA thioesterase
AYN53_RS02980	COG3126	Type III secretion system lipoprotein chaperone (YscW)
AYN53_RS02985	COG3695	enzyme binding
AYN53_RS02995	COG5507	3-demethylubiquinone-9 3-methyltransferase
AYN53_RS03000	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AYN53_RS03010	COG0110	maltose O-acetyltransferase activity
AYN53_RS03025	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AYN53_RS03030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYN53_RS03035	COG1309	transcriptional regulator
AYN53_RS03040	COG1196	nuclear chromosome segregation
AYN53_RS03040	COG3264	Mechanosensitive ion channel
AYN53_RS03050	COG3923	Primosomal replication protein n
AYN53_RS03055	COG2832	Protein of unknown function (DUF454)
AYN53_RS03065	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AYN53_RS03100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AYN53_RS03110	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AYN53_RS03110	COG4651	solute:proton antiporter activity
AYN53_RS03115	COG2223	nitrite transmembrane transporter activity
AYN53_RS03120	COG0737	Belongs to the 5'-nucleotidase family
AYN53_RS03125	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AYN53_RS03130	COG3735	TraB family
AYN53_RS03140	COG2217	Heavy metal translocating P-type atpase
AYN53_RS03150	COG0531	amino acid
AYN53_RS03180	COG0789	Transcriptional regulator
AYN53_RS03190	COG1585	Membrane protein implicated in regulation of membrane protease activity
AYN53_RS03195	COG0330	HflC and HflK could
AYN53_RS03200	COG4619	ABC transporter
AYN53_RS03210	COG3118	belongs to the thioredoxin family
AYN53_RS03215	COG0300	oxidoreductase activity
AYN53_RS03220	COG2755	lipolytic protein G-D-S-L family
AYN53_RS03225	COG4181	ATPase activity
AYN53_RS03230	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AYN53_RS03240	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AYN53_RS03245	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AYN53_RS03260	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AYN53_RS03270	COG1988	membrane-bound metal-dependent
AYN53_RS03275	COG2501	S4 domain
AYN53_RS03285	COG3539	Fimbrial protein
AYN53_RS03290	COG3121	Chaperone
AYN53_RS03295	COG3188	usher protein
AYN53_RS03300	COG3539	Fimbrial protein
AYN53_RS03305	COG3539	Fimbrial protein
AYN53_RS03310	COG2197	response regulator
AYN53_RS03320	COG0582	viral genome integration into host DNA
AYN53_RS03410	COG2076	Multidrug Resistance protein
AYN53_RS03420	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AYN53_RS03425	COG1881	PFAM PEBP family protein
AYN53_RS03430	COG2207	Transcriptional regulator
AYN53_RS03475	COG3272	Protein of unknown function (DUF1722)
AYN53_RS03490	COG2207	Transcriptional regulator
AYN53_RS03530	COG4571	Outer membrane protease
AYN53_RS03540	COG2207	Transcriptional regulator
AYN53_RS03550	COG4783	chaperone-mediated protein folding
AYN53_RS03555	COG1215	transferase activity, transferring glycosyl groups
AYN53_RS03575	COG5002	protein histidine kinase activity
AYN53_RS03580	COG0745	RESPONSE REGULATOR receiver
AYN53_RS03585	COG1538	Outer membrane efflux protein
AYN53_RS03590	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYN53_RS03595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYN53_RS03600	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AYN53_RS03605	COG1113	amino acid transport
AYN53_RS03610	COG0668	transmembrane transport
AYN53_RS03615	COG0778	Nitroreductase
AYN53_RS03620	COG2315	Protein conserved in bacteria
AYN53_RS03655	COG2977	Belongs to the P-Pant transferase superfamily
AYN53_RS03660	COG4771	TonB-dependent receptor
AYN53_RS03665	COG2382	esterase
AYN53_RS03670	COG3251	PFAM MbtH domain protein
AYN53_RS03675	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AYN53_RS03675	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AYN53_RS03680	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
AYN53_RS03685	COG1120	ATPase activity
AYN53_RS03690	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AYN53_RS03695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AYN53_RS03705	COG4592	Periplasmic binding protein
AYN53_RS03710	COG1169	isochorismate synthase
AYN53_RS03715	COG1021	2,3-dihydroxybenzoate-AMP ligase
AYN53_RS03720	COG1535	isochorismatase
AYN53_RS03720	COG3433	isochorismatase activity
AYN53_RS03725	COG1028	Short-chain dehydrogenase reductase Sdr
AYN53_RS03730	COG2050	protein possibly involved in aromatic compounds catabolism
AYN53_RS03735	COG1966	Carbon starvation protein
AYN53_RS03740	COG2879	small protein
AYN53_RS03745	COG0371	Dehydrogenase
AYN53_RS03750	COG0436	Aminotransferase
AYN53_RS03755	COG1475	DNA binding
AYN53_RS03765	COG0583	DNA-binding transcription factor activity
AYN53_RS03770	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AYN53_RS03775	COG0450	alkyl hydroperoxide reductase
AYN53_RS03780	COG3634	alkyl hydroperoxide reductase activity
AYN53_RS03785	COG0589	response to stress
AYN53_RS03790	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AYN53_RS03795	COG3719	Belongs to the RNase T2 family
AYN53_RS03800	COG0471	metal ion transport
AYN53_RS03815	COG3051	citrate lyase alpha subunit
AYN53_RS03820	COG2301	Belongs to the HpcH HpaI aldolase family
AYN53_RS03830	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
AYN53_RS03835	COG3290	protein histidine kinase activity
AYN53_RS03840	COG4565	transcriptional regulatory protein
AYN53_RS03845	COG3069	C4-dicarboxylate transmembrane transporter activity
AYN53_RS03865	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AYN53_RS03870	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AYN53_RS03880	COG0583	DNA-binding transcription factor activity
AYN53_RS03895	COG1686	Belongs to the peptidase S11 family
AYN53_RS03900	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AYN53_RS03905	COG0772	Belongs to the SEDS family
AYN53_RS03910	COG0768	penicillin binding
AYN53_RS03920	COG0799	negative regulation of ribosome biogenesis
AYN53_RS03925	COG0406	alpha-ribazole phosphatase activity
AYN53_RS03935	COG1466	dna polymerase III delta subunit
AYN53_RS03950	COG2888	peptidyl-tyrosine sulfation
AYN53_RS03960	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AYN53_RS03970	COG2214	Heat shock protein DnaJ domain protein
AYN53_RS03975	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AYN53_RS03985	COG2214	Heat shock protein DnaJ domain protein
AYN53_RS03990	COG0443	Heat shock 70 kDa protein
AYN53_RS04000	COG1126	abc transporter atp-binding protein
AYN53_RS04005	COG0765	amino acid transport
AYN53_RS04010	COG0765	amino acid transport
AYN53_RS04015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AYN53_RS04025	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AYN53_RS04030	COG4535	Mg2 and Co2 transporter CorC
AYN53_RS04040	COG1702	phosphate starvation-inducible protein PhoH
AYN53_RS04050	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AYN53_RS04090	COG0367	asparagine synthase
AYN53_RS04095	COG0647	UMP catabolic process
AYN53_RS04100	COG1846	Transcriptional regulator
AYN53_RS04100	COG1940	carbohydrate kinase activity
AYN53_RS04105	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AYN53_RS04115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AYN53_RS04115	COG1263	PTS System
AYN53_RS04115	COG2190	(PTS) system
AYN53_RS04135	COG0735	belongs to the Fur family
AYN53_RS04145	COG0716	FMN binding
AYN53_RS04155	COG0596	Alpha beta hydrolase
AYN53_RS04160	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AYN53_RS04165	COG0033	Phosphoglucomutase
AYN53_RS04170	COG0531	amino acid
AYN53_RS04175	COG1982	Orn Lys Arg decarboxylase major
AYN53_RS04190	COG0745	RESPONSE REGULATOR receiver
AYN53_RS04195	COG2205	protein histidine kinase activity
AYN53_RS04250	COG3272	Protein of unknown function (DUF1722)
AYN53_RS04255	COG0415	Belongs to the DNA photolyase family
AYN53_RS04265	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AYN53_RS04270	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AYN53_RS04275	COG1984	allophanate hydrolase subunit 2
AYN53_RS04290	COG3180	Ammonia monooxygenase
AYN53_RS04295	COG2186	Transcriptional regulator
AYN53_RS04300	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AYN53_RS04300	COG0473	3-isopropylmalate dehydrogenase activity
AYN53_RS04305	COG1063	alcohol dehydrogenase
AYN53_RS04310	COG1028	Short-chain dehydrogenase reductase Sdr
AYN53_RS04320	COG2721	sulfolactate sulfo-lyase activity
AYN53_RS04325	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AYN53_RS04335	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AYN53_RS04340	COG3539	Fimbrial protein
AYN53_RS04345	COG3121	Chaperone
AYN53_RS04355	COG3539	Fimbrial protein
AYN53_RS04360	COG0372	Belongs to the citrate synthase family
AYN53_RS04370	COG2009	succinate dehydrogenase
AYN53_RS04375	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AYN53_RS04380	COG1053	succinate dehydrogenase
AYN53_RS04385	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AYN53_RS04390	COG0567	Dehydrogenase, E1 component
AYN53_RS04395	COG0508	dehydrogenase complex catalyzes the overall conversion of
AYN53_RS04405	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AYN53_RS04420	COG1271	oxidase subunit
AYN53_RS04425	COG1294	oxidase, subunit
AYN53_RS04430	COG4890	Cyd operon protein YbgT
AYN53_RS04435	COG3790	cyd operon protein YbgE
AYN53_RS04440	COG0824	Thioesterase
AYN53_RS04445	COG0811	peptide transport
AYN53_RS04450	COG0848	biopolymer transport protein
AYN53_RS04455	COG3064	Membrane
AYN53_RS04465	COG2885	chlorophyll binding
AYN53_RS04470	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AYN53_RS04530	COG3201	nicotinamide mononucleotide transporter
AYN53_RS04540	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AYN53_RS04550	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AYN53_RS04580	COG2017	converts alpha-aldose to the beta-anomer
AYN53_RS04590	COG1085	galactose-1-phosphate uridylyltransferase
AYN53_RS04595	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AYN53_RS04600	COG1119	ATPase activity
AYN53_RS04605	COG2005	Transcriptional regulator
AYN53_RS04605	COG3585	molybdate ion transport
AYN53_RS04615	COG0725	ABC transporter, periplasmic molybdate-binding protein
AYN53_RS04620	COG4149	molybdate abc transporter
AYN53_RS04630	COG0561	phosphatase activity
AYN53_RS04640	COG0583	DNA-binding transcription factor activity
AYN53_RS04645	COG2828	Protein conserved in bacteria
AYN53_RS04650	COG0471	metal ion transport
AYN53_RS04655	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AYN53_RS04660	COG4677	pectinesterase activity
AYN53_RS04670	COG2267	carboxylic ester hydrolase activity
AYN53_RS04690	COG1881	PFAM PEBP family protein
AYN53_RS04695	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AYN53_RS04710	COG2226	methyltransferase
AYN53_RS04715	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AYN53_RS04725	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AYN53_RS04735	COG0521	Mo-molybdopterin cofactor biosynthetic process
AYN53_RS04745	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AYN53_RS04750	COG0314	molybdopterin synthase activity
AYN53_RS04755	COG0670	Belongs to the BI1 family
AYN53_RS04785	COG0842	Transport permease protein
AYN53_RS04790	COG0842	Transport permease protein
AYN53_RS04795	COG1131	(ABC) transporter
AYN53_RS04805	COG1309	transcriptional regulator
AYN53_RS04810	COG0513	Belongs to the DEAD box helicase family
AYN53_RS04820	COG1199	ATP-dependent helicase activity
AYN53_RS04825	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AYN53_RS04830	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AYN53_RS04840	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AYN53_RS04855	COG1126	abc transporter atp-binding protein
AYN53_RS04860	COG0765	amino acid transport
AYN53_RS04865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AYN53_RS04875	COG5006	permease, DMT superfamily
AYN53_RS04885	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AYN53_RS04890	COG2194	sulfuric ester hydrolase activity
AYN53_RS04900	COG1321	iron dependent repressor
AYN53_RS04905	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AYN53_RS04910	COG1376	ErfK ybiS ycfS ynhG family protein
AYN53_RS04915	COG0488	(ABC) transporter
AYN53_RS04920	COG0561	phosphatase activity
AYN53_RS04925	COG1882	Formate acetyltransferase
AYN53_RS04930	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AYN53_RS04935	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AYN53_RS04940	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AYN53_RS04945	COG0303	'Molybdopterin
AYN53_RS04950	COG1446	asparaginase
AYN53_RS04960	COG0747	negative chemotaxis
AYN53_RS04975	COG2200	EAL domain
AYN53_RS04980	COG2199	diguanylate cyclase activity
AYN53_RS04985	COG1413	lyase activity
AYN53_RS05010	COG0625	glutathione transferase activity
AYN53_RS05015	COG1686	Belongs to the peptidase S11 family
AYN53_RS05020	COG1349	DNA-binding transcription factor activity
AYN53_RS05025	COG0671	phosphoesterase, PA-phosphatase related
AYN53_RS05030	COG2814	Major facilitator Superfamily
AYN53_RS05040	COG0561	phosphatase activity
AYN53_RS05045	COG0738	Major facilitator superfamily
AYN53_RS05050	COG3226	Transcriptional regulator
AYN53_RS05055	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AYN53_RS05100	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AYN53_RS05130	COG4695	Portal protein
AYN53_RS05230	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AYN53_RS05245	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AYN53_RS05300	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AYN53_RS05310	COG0778	Nitroreductase
AYN53_RS05325	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AYN53_RS05330	COG3842	ATPase activity
AYN53_RS05335	COG1176	ABC-type spermidine putrescine transport system, permease component I
AYN53_RS05340	COG1177	transmembrane transport
AYN53_RS05355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AYN53_RS05360	COG4160	amino acid transport
AYN53_RS05365	COG4215	(ABC) transporter
AYN53_RS05370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AYN53_RS05375	COG1126	abc transporter atp-binding protein
AYN53_RS05390	COG3023	N-Acetylmuramoyl-L-alanine amidase
AYN53_RS05395	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AYN53_RS05400	COG0702	epimerase
AYN53_RS05405	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AYN53_RS05410	COG0028	Belongs to the TPP enzyme family
AYN53_RS05415	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AYN53_RS05425	COG2431	L-lysine efflux transmembrane transporter activity
AYN53_RS05440	COG3593	DNA synthesis involved in DNA repair
AYN53_RS05445	COG2990	Protein conserved in bacteria
AYN53_RS05450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYN53_RS05460	COG1278	Cold shock
AYN53_RS05470	COG0542	response to heat
AYN53_RS05490	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AYN53_RS05495	COG4988	ABC transporter
AYN53_RS05500	COG0492	ferredoxin-NADP+ reductase activity
AYN53_RS05505	COG1522	sequence-specific DNA binding
AYN53_RS05510	COG1178	ABC-type Fe3 transport system permease component
AYN53_RS05510	COG1674	ftsk spoiiie
AYN53_RS05520	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AYN53_RS05530	COG0243	molybdopterin cofactor binding
AYN53_RS05535	COG0437	4 iron, 4 sulfur cluster binding
AYN53_RS05540	COG3302	dmso reductase anchor subunit
AYN53_RS05545	COG1335	isochorismatase
AYN53_RS05555	COG0531	amino acid
AYN53_RS05565	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AYN53_RS05570	COG1882	Formate acetyltransferase
AYN53_RS05575	COG2116	formate transmembrane transporter activity
AYN53_RS05580	COG1944	ATP diphosphatase activity
AYN53_RS05600	COG0539	negative regulation of cytoplasmic translation
AYN53_RS05610	COG0658	competence protein
AYN53_RS05610	COG2333	competence protein COMEC
AYN53_RS05625	COG3214	Protein conserved in bacteria
AYN53_RS05640	COG3173	Aminoglycoside phosphotransferase
AYN53_RS05645	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AYN53_RS05650	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AYN53_RS05660	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
AYN53_RS05670	COG2989	Protein conserved in bacteria
AYN53_RS05675	COG3108	Peptidase M15
AYN53_RS05680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AYN53_RS05685	COG1448	Aminotransferase
AYN53_RS05705	COG0308	aminopeptidase N
AYN53_RS05730	COG0488	(ABC) transporter
AYN53_RS05735	COG2995	paraquat-inducible protein a
AYN53_RS05740	COG3008	intermembrane lipid transfer
AYN53_RS05740	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AYN53_RS05745	COG3009	Protein conserved in bacteria
AYN53_RS05750	COG3130	regulation of translation
AYN53_RS05760	COG1067	ATP-dependent peptidase activity
AYN53_RS05780	COG3070	regulator of competence-specific genes
AYN53_RS05785	COG1289	transmembrane transporter activity
AYN53_RS05790	COG3304	Inner membrane component domain
AYN53_RS05795	COG0210	DNA helicase
AYN53_RS05810	COG1832	CoA-binding protein
AYN53_RS05825	COG1254	Belongs to the acylphosphatase family
AYN53_RS05830	COG2920	part of a sulfur-relay system
AYN53_RS05835	COG0670	Belongs to the BI1 family
AYN53_RS05850	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AYN53_RS05855	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AYN53_RS05860	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
AYN53_RS05865	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AYN53_RS05870	COG1999	signal sequence binding
AYN53_RS05875	COG1773	rubredoxin
AYN53_RS05880	COG1271	oxidase subunit
AYN53_RS05885	COG1294	oxidase, subunit
AYN53_RS05900	COG0489	protein tyrosine kinase activity
AYN53_RS05900	COG3206	protein involved in exopolysaccharide biosynthesis
AYN53_RS05905	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AYN53_RS05910	COG1596	polysaccharide export
AYN53_RS05915	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AYN53_RS05935	COG1278	Cold shock
AYN53_RS05940	COG1278	Cold shock
AYN53_RS05960	COG0348	domain, Protein
AYN53_RS05965	COG2205	protein histidine kinase activity
AYN53_RS05965	COG2198	Histidine kinase
AYN53_RS05965	COG0784	Response regulator, receiver
AYN53_RS05970	COG0745	RESPONSE REGULATOR receiver
AYN53_RS05975	COG3005	denitrification pathway
AYN53_RS05980	COG0243	molybdopterin cofactor binding
AYN53_RS05985	COG3381	protein complex oligomerization
AYN53_RS06020	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AYN53_RS06075	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AYN53_RS06080	COG3729	General stress protein
AYN53_RS06085	COG1309	transcriptional regulator
AYN53_RS06090	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AYN53_RS06090	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AYN53_RS06090	COG0506	proline dehydrogenase activity
AYN53_RS06100	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AYN53_RS06120	COG1702	phosphate starvation-inducible protein PhoH
AYN53_RS06150	COG3381	protein complex oligomerization
AYN53_RS06160	COG1462	curli production assembly transport component CsgG
AYN53_RS06175	COG2197	response regulator
AYN53_RS06200	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AYN53_RS06205	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AYN53_RS06220	COG2943	transferase activity, transferring hexosyl groups
AYN53_RS06225	COG5645	(Lipo)protein
AYN53_RS06300	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AYN53_RS06310	COG1560	Kdo2-lipid A biosynthetic process
AYN53_RS06355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AYN53_RS06365	COG0673	inositol 2-dehydrogenase activity
AYN53_RS06370	COG0728	peptidoglycan biosynthetic process
AYN53_RS06375	COG3418	PFAM FlgN family protein
AYN53_RS06380	COG2747	anti-sigma28 factor FlgM
AYN53_RS06385	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
AYN53_RS06390	COG1815	bacterial-type flagellum-dependent cell motility
AYN53_RS06395	COG1558	bacterial-type flagellum-dependent cell motility
AYN53_RS06400	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AYN53_RS06405	COG1749	Flagellar hook protein flgE
AYN53_RS06410	COG4787	bacterial-type flagellum-dependent cell motility
AYN53_RS06415	COG4786	Flagellar basal body rod
AYN53_RS06425	COG1706	bacterial-type flagellum-dependent cell motility
AYN53_RS06430	COG1705	Flagellar rod assembly protein muramidase FlgJ
AYN53_RS06430	COG3951	Flagellar rod assembly protein muramidase FlgJ
AYN53_RS06435	COG1256	bacterial-type flagellum assembly
AYN53_RS06440	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AYN53_RS06445	COG1530	ribonuclease E activity
AYN53_RS06455	COG0564	pseudouridine synthase activity
AYN53_RS06460	COG0424	maF-like protein
AYN53_RS06465	COG1399	metal-binding, possibly nucleic acid-binding protein
AYN53_RS06485	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AYN53_RS06490	COG1028	Short-chain dehydrogenase reductase Sdr
AYN53_RS06500	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AYN53_RS06505	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AYN53_RS06510	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AYN53_RS06520	COG0470	DNA polymerase III
AYN53_RS06525	COG0084	hydrolase, TatD family'
AYN53_RS06530	COG1263	PTS System
AYN53_RS06530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AYN53_RS06540	COG0537	adenosine 5'-monophosphoramidase activity
AYN53_RS06545	COG5633	Lipoprotein
AYN53_RS06550	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
AYN53_RS06570	COG1252	NADH dehydrogenase
AYN53_RS06575	COG3134	Outer membrane lipoprotein
AYN53_RS06580	COG1309	transcriptional regulator
AYN53_RS06590	COG1376	ErfK ybiS ycfS ynhG family protein
AYN53_RS06590	COG1388	LysM domain
AYN53_RS06595	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AYN53_RS06600	COG4591	ABC-type transport system involved in lipoprotein release permease component
AYN53_RS06610	COG4591	ABC-type transport system involved in lipoprotein release permease component
AYN53_RS06620	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AYN53_RS06625	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AYN53_RS06635	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AYN53_RS06640	COG1177	transmembrane transport
AYN53_RS06650	COG3842	ATPase activity
AYN53_RS06660	COG2850	peptidyl-arginine hydroxylation
AYN53_RS06665	COG2205	protein histidine kinase activity
AYN53_RS06675	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AYN53_RS06695	COG1187	pseudouridine synthase activity
AYN53_RS06700	COG0538	isocitrate dehydrogenase activity
AYN53_RS06705	COG1073	alpha beta
AYN53_RS06710	COG0583	DNA-binding transcription factor activity
AYN53_RS06745	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AYN53_RS06750	COG4571	Outer membrane protease
AYN53_RS06790	COG2894	cell division
AYN53_RS06805	COG0179	Fumarylacetoacetate (FAA) hydrolase
AYN53_RS06830	COG3477	response to acidic pH
AYN53_RS06835	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AYN53_RS06850	COG2719	SpoVR family
AYN53_RS06860	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AYN53_RS06870	COG1619	proteins homologs of microcin C7 resistance protein MccF
AYN53_RS06880	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
AYN53_RS06895	COG0157	Belongs to the NadC ModD family
AYN53_RS06900	COG0500	methyltransferase
AYN53_RS06905	COG1120	ATPase activity
AYN53_RS06910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AYN53_RS06915	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AYN53_RS06940	COG0012	GTP binding
AYN53_RS06955	COG0659	secondary active sulfate transmembrane transporter activity
AYN53_RS06960	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AYN53_RS06985	COG2890	protein-(glutamine-N5) methyltransferase activity
AYN53_RS06990	COG3094	Invasion gene expression up-regulator, SirB
AYN53_RS06995	COG2912	Transglutaminase-like superfamily
AYN53_RS07015	COG0737	Belongs to the 5'-nucleotidase family
AYN53_RS07025	COG0737	Belongs to the 5'-nucleotidase family
AYN53_RS07030	COG0641	radical SAM
AYN53_RS07035	COG0387	Pfam Sodium calcium exchanger
AYN53_RS07045	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AYN53_RS07050	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AYN53_RS07055	COG2197	response regulator
AYN53_RS07060	COG3850	Histidine kinase
AYN53_RS07065	COG2223	nitrite transmembrane transporter activity
AYN53_RS07070	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AYN53_RS07075	COG1140	nitrate reductase beta subunit
AYN53_RS07080	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AYN53_RS07085	COG2181	nitrate reductase activity
AYN53_RS07090	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AYN53_RS07135	COG0788	formyltetrahydrofolate deformylase activity
AYN53_RS07145	COG1752	Esterase of the alpha-beta hydrolase superfamily
AYN53_RS07150	COG0745	RESPONSE REGULATOR receiver
AYN53_RS07155	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AYN53_RS07165	COG1435	thymidine kinase activity
AYN53_RS07170	COG1012	belongs to the aldehyde dehydrogenase family
AYN53_RS07170	COG1454	alcohol dehydrogenase
AYN53_RS07175	COG2095	MarC family integral membrane protein
AYN53_RS07180	COG4166	transmembrane transport
AYN53_RS07185	COG0601	transmembrane transport
AYN53_RS07190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AYN53_RS07195	COG0444	Belongs to the ABC transporter superfamily
AYN53_RS07200	COG4608	Belongs to the ABC transporter superfamily
AYN53_RS07205	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AYN53_RS07225	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AYN53_RS07230	COG2350	Protein conserved in bacteria
AYN53_RS07235	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AYN53_RS07245	COG1607	acyl-coa hydrolase
AYN53_RS07260	COG0727	PFAM Uncharacterised protein family (UPF0153)
AYN53_RS07265	COG3047	cAMP biosynthetic process
AYN53_RS07270	COG0582	viral genome integration into host DNA
AYN53_RS07280	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AYN53_RS07325	COG1846	Transcriptional regulator
AYN53_RS07330	COG1484	DNA-dependent DNA replication
AYN53_RS07335	COG1846	Transcriptional regulator
AYN53_RS07375	COG1403	HNH endonuclease
AYN53_RS07380	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
AYN53_RS07385	COG0484	heat shock protein binding
AYN53_RS07410	COG3772	lysozyme
AYN53_RS07520	COG5301	cellulose 1,4-beta-cellobiosidase activity
AYN53_RS07560	COG0727	PFAM Uncharacterised protein family (UPF0153)
AYN53_RS07585	COG0134	indole-3-glycerol-phosphate synthase activity
AYN53_RS07585	COG0135	phosphoribosylanthranilate isomerase activity
AYN53_RS07590	COG0512	Glutamine amidotransferase of anthranilate synthase
AYN53_RS07590	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AYN53_RS07595	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AYN53_RS07605	COG0613	PHP domain protein
AYN53_RS07610	COG0009	L-threonylcarbamoyladenylate synthase
AYN53_RS07615	COG1187	pseudouridine synthase activity
AYN53_RS07630	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
AYN53_RS07635	COG1028	Short-chain dehydrogenase reductase Sdr
AYN53_RS07640	COG0616	signal peptide processing
AYN53_RS07650	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AYN53_RS07655	COG0583	DNA-binding transcription factor activity
AYN53_RS07665	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AYN53_RS07675	COG0671	phosphoesterase, PA-phosphatase related
AYN53_RS07680	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AYN53_RS07685	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AYN53_RS07695	COG0023	Translation Initiation Factor
AYN53_RS07705	COG1349	DNA-binding transcription factor activity
AYN53_RS07715	COG5001	Diguanylate cyclase
AYN53_RS07730	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AYN53_RS07730	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AYN53_RS07735	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AYN53_RS07745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYN53_RS07760	COG2814	Major facilitator Superfamily
AYN53_RS07765	COG4172	Belongs to the ABC transporter superfamily
AYN53_RS07770	COG4172	Belongs to the ABC transporter superfamily
AYN53_RS07775	COG4171	peptide transport system, permease
AYN53_RS07785	COG2076	Multidrug Resistance protein
AYN53_RS07790	COG1881	PFAM PEBP family protein
AYN53_RS07795	COG2207	Transcriptional regulator
AYN53_RS07805	COG1073	alpha beta
AYN53_RS07810	COG0583	DNA-binding transcription factor activity
AYN53_RS07815	COG4168	peptide transport system, permease
AYN53_RS07820	COG4166	transmembrane transport
AYN53_RS07830	COG0531	amino acid
AYN53_RS07840	COG0174	glutamine synthetase
AYN53_RS07845	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AYN53_RS07850	COG1396	sequence-specific DNA binding
AYN53_RS07850	COG1917	Cupin 2, conserved barrel domain protein
AYN53_RS07855	COG1012	belongs to the aldehyde dehydrogenase family
AYN53_RS07860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AYN53_RS07865	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AYN53_RS07870	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AYN53_RS07875	COG1842	Phage shock protein A
AYN53_RS07885	COG1983	PspC domain protein
AYN53_RS07895	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AYN53_RS07900	COG3106	COG3106 Predicted ATPase
AYN53_RS07910	COG3283	Transcriptional regulator of aromatic amino acids metabolism
AYN53_RS07915	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AYN53_RS07920	COG4948	Mandelate Racemase Muconate Lactonizing
AYN53_RS07925	COG2866	Carboxypeptidase
AYN53_RS07930	COG4166	transmembrane transport
AYN53_RS07935	COG0668	transmembrane transport
AYN53_RS07940	COG3182	Iron-regulated membrane protein
AYN53_RS07945	COG0589	response to stress
AYN53_RS07950	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AYN53_RS07955	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AYN53_RS07960	COG2840	Smr protein MutS2
AYN53_RS07965	COG3706	GGDEF domain
AYN53_RS07980	COG0513	Belongs to the DEAD box helicase family
AYN53_RS07990	COG0582	viral genome integration into host DNA
AYN53_RS08070	COG3756	Protein conserved in bacteria
AYN53_RS08075	COG1484	DNA-dependent DNA replication
AYN53_RS08080	COG1846	Transcriptional regulator
AYN53_RS08170	COG0589	response to stress
AYN53_RS08175	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AYN53_RS08180	COG1013	pyruvate-flavodoxin oxidoreductase activity
AYN53_RS08180	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AYN53_RS08180	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AYN53_RS08180	COG0674	pyruvate-flavodoxin oxidoreductase activity
AYN53_RS08185	COG3042	response to heat
AYN53_RS08190	COG3187	Heat shock protein
AYN53_RS08195	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AYN53_RS08210	COG2911	Protein conserved in bacteria
AYN53_RS08220	COG3784	Protein of unknown function (DUF1318)
AYN53_RS08225	COG0667	Aldo Keto reductase
AYN53_RS08240	COG1643	Atp-dependent helicase
AYN53_RS08265	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AYN53_RS08270	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AYN53_RS08275	COG3038	cytochrome b561
AYN53_RS08280	COG0583	DNA-binding transcription factor activity
AYN53_RS08285	COG5383	Protein conserved in bacteria
AYN53_RS08295	COG2841	Protein conserved in bacteria
AYN53_RS08300	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AYN53_RS08305	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AYN53_RS08310	COG1275	C4-dicarboxylate transporter malic acid transport protein
AYN53_RS08315	COG0500	methyltransferase
AYN53_RS08325	COG0826	peptidase U32
AYN53_RS08335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AYN53_RS08340	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AYN53_RS08345	COG3842	ATPase activity
AYN53_RS08350	COG1176	ABC-type spermidine putrescine transport system, permease component I
AYN53_RS08355	COG1177	transmembrane transport
AYN53_RS08365	COG1388	LysM domain
AYN53_RS08365	COG1470	cell adhesion involved in biofilm formation
AYN53_RS08385	COG3238	Protein conserved in bacteria
AYN53_RS08390	COG1247	-acetyltransferase
AYN53_RS08395	COG2130	NADP-dependent
AYN53_RS08410	COG1113	amino acid transport
AYN53_RS08430	COG3209	COG3209 Rhs family protein
AYN53_RS08465	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AYN53_RS08475	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AYN53_RS08480	COG0384	phenazine biosynthesis protein PhzF
AYN53_RS08490	COG2181	nitrate reductase activity
AYN53_RS08495	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AYN53_RS08500	COG1140	nitrate reductase beta subunit
AYN53_RS08505	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AYN53_RS08510	COG2223	nitrite transmembrane transporter activity
AYN53_RS08520	COG0697	spore germination
AYN53_RS08525	COG3383	formate dehydrogenase (NAD+) activity
AYN53_RS08525	COG0243	molybdopterin cofactor binding
AYN53_RS08530	COG3383	formate dehydrogenase (NAD+) activity
AYN53_RS08530	COG0243	molybdopterin cofactor binding
AYN53_RS08535	COG0437	4 iron, 4 sulfur cluster binding
AYN53_RS08540	COG2864	formate dehydrogenase
AYN53_RS08545	COG3093	addiction module antidote protein HigA
AYN53_RS08555	COG1064	alcohol dehydrogenase
AYN53_RS08570	COG1764	response to oxidative stress
AYN53_RS08575	COG2202	Pas domain
AYN53_RS08575	COG2199	diguanylate cyclase activity
AYN53_RS08575	COG2200	EAL domain
AYN53_RS08585	COG1649	PFAM Uncharacterised BCR, COG1649
AYN53_RS08590	COG0531	amino acid
AYN53_RS08615	COG3781	membrane
AYN53_RS08625	COG2199	diguanylate cyclase activity
AYN53_RS08635	COG2066	Belongs to the glutaminase family
AYN53_RS08640	COG1012	belongs to the aldehyde dehydrogenase family
AYN53_RS08645	COG0583	DNA-binding transcription factor activity
AYN53_RS08665	COG1846	Transcriptional regulator
AYN53_RS08670	COG4977	sequence-specific DNA binding
AYN53_RS08680	COG2723	6-phospho-beta-galactosidase activity
AYN53_RS08690	COG1447	Phosphotransferase system cellobiose-specific component IIA
AYN53_RS08695	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AYN53_RS08705	COG2188	Transcriptional regulator
AYN53_RS08710	COG0697	spore germination
AYN53_RS08715	COG2814	Major facilitator Superfamily
AYN53_RS08725	COG3706	GGDEF domain
AYN53_RS08730	COG0339	signal peptide processing
AYN53_RS08735	COG4221	oxidoreductase activity
AYN53_RS08740	COG1802	Transcriptional regulator
AYN53_RS08750	COG0246	Mannitol dehydrogenase
AYN53_RS08755	COG0477	Major facilitator Superfamily
AYN53_RS08760	COG1063	alcohol dehydrogenase
AYN53_RS08765	COG4948	Mandelate Racemase Muconate Lactonizing
AYN53_RS08780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AYN53_RS08795	COG0243	molybdopterin cofactor binding
AYN53_RS08800	COG0243	molybdopterin cofactor binding
AYN53_RS08805	COG0437	4 iron, 4 sulfur cluster binding
AYN53_RS08810	COG3302	dmso reductase anchor subunit
AYN53_RS08815	COG3381	protein complex oligomerization
AYN53_RS08825	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AYN53_RS08830	COG1940	carbohydrate kinase activity
AYN53_RS08835	COG0583	DNA-binding transcription factor activity
AYN53_RS08840	COG2814	Major facilitator Superfamily
AYN53_RS08855	COG3591	Belongs to the peptidase S1B family
AYN53_RS08870	COG0628	permease
AYN53_RS08875	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AYN53_RS08880	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AYN53_RS08890	COG0531	amino acid
AYN53_RS08900	COG3136	membrane protein required for alginate biosynthesis
AYN53_RS08905	COG0745	RESPONSE REGULATOR receiver
AYN53_RS08910	COG2205	protein histidine kinase activity
AYN53_RS08920	COG0114	fumarate hydratase activity
AYN53_RS08925	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AYN53_RS08925	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AYN53_RS08930	COG1482	cell wall glycoprotein biosynthetic process
AYN53_RS08935	COG5339	Protein conserved in bacteria
AYN53_RS08940	COG1028	Short-chain dehydrogenase reductase Sdr
AYN53_RS08945	COG1609	Transcriptional regulator
AYN53_RS08950	COG1263	PTS System
AYN53_RS08950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AYN53_RS08955	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AYN53_RS08965	COG0673	inositol 2-dehydrogenase activity
AYN53_RS09005	COG4659	FMN binding
AYN53_RS09010	COG4660	Part of a membrane complex involved in electron transport
AYN53_RS09015	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AYN53_RS09020	COG3104	oligopeptide transport
AYN53_RS09025	COG0625	glutathione transferase activity
AYN53_RS09030	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AYN53_RS09045	COG3895	Periplasmic Protein
AYN53_RS09055	COG3133	Outer membrane lipoprotein
AYN53_RS09070	COG1566	PFAM secretion protein HlyD family protein
AYN53_RS09075	COG1289	transmembrane transporter activity
AYN53_RS09080	COG4989	oxidoreductase activity
AYN53_RS09085	COG3313	Fe-S protein
AYN53_RS09095	COG1309	transcriptional regulator
AYN53_RS09105	COG0346	lactoylglutathione lyase activity
AYN53_RS09120	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AYN53_RS09125	COG0791	NLP P60 protein
AYN53_RS09130	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AYN53_RS09145	COG0583	DNA-binding transcription factor activity
AYN53_RS09150	COG2814	Major facilitator Superfamily
AYN53_RS09155	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AYN53_RS09160	COG0307	riboflavin synthase, alpha
AYN53_RS09170	COG3468	outer membrane autotransporter barrel domain protein
AYN53_RS09195	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
AYN53_RS09200	COG0437	4 iron, 4 sulfur cluster binding
AYN53_RS09210	COG2414	aldehyde ferredoxin oxidoreductase
AYN53_RS09215	COG0437	4 iron, 4 sulfur cluster binding
AYN53_RS09225	COG0469	pyruvate kinase activity
AYN53_RS09230	COG4238	major outer membrane lipoprotein
AYN53_RS09235	COG1376	ErfK ybiS ycfS ynhG family protein
AYN53_RS09250	COG0719	Fe-S assembly protein
AYN53_RS09255	COG0396	ATPase activity
AYN53_RS09260	COG0719	Fe-S assembly protein
AYN53_RS09265	COG0316	Belongs to the HesB IscA family
AYN53_RS09275	COG2050	protein possibly involved in aromatic compounds catabolism
AYN53_RS09280	COG0277	FAD linked oxidase domain protein
AYN53_RS09280	COG0247	lactate metabolic process
AYN53_RS09285	COG0628	permease
AYN53_RS09300	COG0738	Major facilitator superfamily
AYN53_RS09310	COG2271	Major facilitator Superfamily
AYN53_RS09330	COG1960	acyl-CoA dehydrogenase activity
AYN53_RS09335	COG2207	Transcriptional regulator
AYN53_RS09335	COG1917	Cupin 2, conserved barrel domain protein
AYN53_RS09340	COG2086	electron transfer activity
AYN53_RS09345	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AYN53_RS09350	COG0644	oxidoreductase
AYN53_RS09355	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AYN53_RS09360	COG0318	PFAM AMP-dependent synthetase and ligase
AYN53_RS09365	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AYN53_RS09365	COG0574	Belongs to the PEP-utilizing enzyme family
AYN53_RS09375	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AYN53_RS09385	COG2200	EAL domain
AYN53_RS09390	COG0791	NLP P60 protein
AYN53_RS09400	COG0386	Belongs to the glutathione peroxidase family
AYN53_RS09460	COG3137	Salt-induced outer membrane protein
AYN53_RS09465	COG1105	Belongs to the carbohydrate kinase PfkB family
AYN53_RS09475	COG3001	Fructosamine kinase
AYN53_RS09480	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AYN53_RS09485	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
AYN53_RS09495	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AYN53_RS09500	COG1988	membrane-bound metal-dependent
AYN53_RS09505	COG1823	symporter activity
AYN53_RS09520	COG3394	polysaccharide catabolic process
AYN53_RS09525	COG1486	melibiose metabolic process
AYN53_RS09530	COG1917	Cupin 2, conserved barrel domain protein
AYN53_RS09530	COG2169	Transcriptional regulator
AYN53_RS09535	COG1447	Phosphotransferase system cellobiose-specific component IIA
AYN53_RS09540	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AYN53_RS09545	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AYN53_RS09555	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AYN53_RS09605	COG5301	cellulose 1,4-beta-cellobiosidase activity
AYN53_RS09700	COG4695	Portal protein
AYN53_RS09720	COG1802	Transcriptional regulator
AYN53_RS09720	COG4626	Terminase
AYN53_RS09825	COG0582	viral genome integration into host DNA
AYN53_RS09850	COG3772	lysozyme
AYN53_RS09875	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
AYN53_RS09880	COG1403	HNH endonuclease
AYN53_RS09985	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AYN53_RS09995	COG0582	viral genome integration into host DNA
AYN53_RS10005	COG3678	ATP-independent chaperone mediated protein folding
AYN53_RS10035	COG0708	Exodeoxyribonuclease III
AYN53_RS10040	COG0398	Pfam SNARE associated Golgi protein
AYN53_RS10050	COG0398	Pfam SNARE associated Golgi protein
AYN53_RS10055	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AYN53_RS10060	COG4134	Bacterial extracellular solute-binding protein
AYN53_RS10065	COG4135	transport system, permease component
AYN53_RS10070	COG4136	ATPase activity
AYN53_RS10075	COG2897	thiosulfate sulfurtransferase activity
AYN53_RS10080	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AYN53_RS10085	COG0494	nUDIX hydrolase
AYN53_RS10095	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AYN53_RS10100	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AYN53_RS10110	COG0778	Nitroreductase
AYN53_RS10115	COG0616	signal peptide processing
AYN53_RS10125	COG0252	asparaginase activity
AYN53_RS10130	COG1335	isochorismatase
AYN53_RS10145	COG3139	Protein of unknown function (DUF1315)
AYN53_RS10155	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AYN53_RS10160	COG0676	glucose-6-phosphate 1-epimerase activity
AYN53_RS10165	COG3713	MltA-interacting MipA family protein
AYN53_RS10170	COG2766	serine protein kinase
AYN53_RS10180	COG2199	diguanylate cyclase activity
AYN53_RS10185	COG2199	diguanylate cyclase activity
AYN53_RS10200	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AYN53_RS10215	COG3189	MarR family transcriptional regulator
AYN53_RS10220	COG3042	response to heat
AYN53_RS10225	COG2203	Gaf domain
AYN53_RS10225	COG2199	diguanylate cyclase activity
AYN53_RS10245	COG3615	Tellurite resistance protein tehB
AYN53_RS10255	COG0583	DNA-binding transcription factor activity
AYN53_RS10260	COG0473	3-isopropylmalate dehydrogenase activity
AYN53_RS10265	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AYN53_RS10270	COG4638	Rieske (2fe-2S)
AYN53_RS10275	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AYN53_RS10280	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AYN53_RS10285	COG0318	PFAM AMP-dependent synthetase and ligase
AYN53_RS10290	COG3065	identical protein binding
AYN53_RS10295	COG1214	PFAM Peptidase M22, glycoprotease
AYN53_RS10300	COG1199	ATP-dependent helicase activity
AYN53_RS10305	COG0251	oxidation-reduction process
AYN53_RS10320	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AYN53_RS10330	COG1760	l-serine dehydratase
AYN53_RS10335	COG2200	EAL domain
AYN53_RS10340	COG1253	flavin adenine dinucleotide binding
AYN53_RS10345	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN53_RS10345	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AYN53_RS10350	COG3715	PTS system
AYN53_RS10355	COG3716	PTS system mannose fructose sorbose family IID component
AYN53_RS10370	COG2226	methyltransferase
AYN53_RS10400	COG1414	Transcriptional regulator
AYN53_RS10405	COG2814	Major facilitator Superfamily
AYN53_RS10415	COG0793	Belongs to the peptidase S41A family
AYN53_RS10425	COG1956	GAF domain-containing protein
AYN53_RS10430	COG2995	paraquat-inducible protein a
AYN53_RS10435	COG3008	intermembrane lipid transfer
AYN53_RS10455	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AYN53_RS10480	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AYN53_RS10500	COG1276	copper resistance
AYN53_RS10505	COG2372	response to copper ion
AYN53_RS10515	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AYN53_RS10515	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AYN53_RS10520	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AYN53_RS10525	COG1770	oligopeptidase
AYN53_RS10535	COG3141	response to X-ray
AYN53_RS10545	COG0800	Aldolase
AYN53_RS10550	COG0129	dihydroxy-acid dehydratase activity
AYN53_RS10555	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AYN53_RS10560	COG1737	Transcriptional regulator
AYN53_RS10565	COG0469	pyruvate kinase activity
AYN53_RS10570	COG1560	Kdo2-lipid A biosynthetic process
AYN53_RS10575	COG0739	heme binding
AYN53_RS10580	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AYN53_RS10590	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AYN53_RS10620	COG0217	transcriptional regulatory protein
AYN53_RS10625	COG0494	nUDIX hydrolase
AYN53_RS10635	COG1335	isochorismatase
AYN53_RS10640	COG1801	Protein of unknown function DUF72
AYN53_RS10645	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AYN53_RS10665	COG3005	denitrification pathway
AYN53_RS10675	COG3102	Protein conserved in bacteria
AYN53_RS10690	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AYN53_RS10695	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AYN53_RS10710	COG1360	Flagellar Motor Protein
AYN53_RS10715	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AYN53_RS10730	COG0589	response to stress
AYN53_RS10735	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AYN53_RS10745	COG1172	Belongs to the binding-protein-dependent transport system permease family
AYN53_RS10760	COG1528	Iron-storage protein
AYN53_RS10780	COG1528	Iron-storage protein
AYN53_RS10790	COG0814	amino acid
AYN53_RS10795	COG3012	SEC-C Motif Domain Protein
AYN53_RS10795	COG3318	Belongs to the UPF0149 family
AYN53_RS10825	COG2197	response regulator
AYN53_RS10840	COG2197	response regulator
AYN53_RS10845	COG1126	abc transporter atp-binding protein
AYN53_RS10850	COG0765	amino acid transport
AYN53_RS10860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AYN53_RS10870	COG1191	sigma factor activity
AYN53_RS10875	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AYN53_RS10880	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AYN53_RS10885	COG1516	flagellar protein fliS
AYN53_RS10895	COG0366	Alpha amylase catalytic
AYN53_RS10905	COG2391	methyltransferase activity
AYN53_RS10910	COG0425	Belongs to the sulfur carrier protein TusA family
AYN53_RS10930	COG1766	The M ring may be actively involved in energy transduction
AYN53_RS10935	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AYN53_RS10940	COG1317	bacterial-type flagellum organization
AYN53_RS10945	COG1157	protein secretion by the type III secretion system
AYN53_RS10950	COG2882	bacterial-type flagellum organization
AYN53_RS10955	COG3144	bacterial-type flagellum assembly
AYN53_RS10960	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AYN53_RS10965	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AYN53_RS10970	COG3190	flagellar
AYN53_RS10975	COG1338	Plays a role in the flagellum-specific transport system
AYN53_RS10980	COG1987	bacterial-type flagellum assembly
AYN53_RS10985	COG1684	flagellar biosynthetic protein fliR
AYN53_RS11010	COG5475	Uncharacterized small protein (DUF2158)
AYN53_RS11015	COG2354	Protein conserved in bacteria
AYN53_RS11020	COG0697	spore germination
AYN53_RS11025	COG3727	T/G mismatch-specific endonuclease activity
AYN53_RS11030	COG0270	DNA (cytosine-5-)-methyltransferase activity
AYN53_RS11035	COG1418	mRNA catabolic process
AYN53_RS11055	COG2205	protein histidine kinase activity
AYN53_RS11060	COG0745	RESPONSE REGULATOR receiver
AYN53_RS11065	COG2351	hydroxyisourate hydrolase activity
AYN53_RS11080	COG3443	Belongs to the bacterial solute-binding protein 9 family
AYN53_RS11120	COG5301	cellulose 1,4-beta-cellobiosidase activity
AYN53_RS11200	COG1030	water channel activity
AYN53_RS11220	COG4220	transposase activity
AYN53_RS11245	COG3772	lysozyme
AYN53_RS11290	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
AYN53_RS11295	COG1403	HNH endonuclease
AYN53_RS11345	COG1846	Transcriptional regulator
AYN53_RS11350	COG1484	DNA-dependent DNA replication
AYN53_RS11355	COG1846	Transcriptional regulator
AYN53_RS11365	COG4197	protein conserved in bacteria, prophage-related
AYN53_RS11400	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AYN53_RS11430	COG0583	DNA-binding transcription factor activity
AYN53_RS11455	COG0477	Major facilitator Superfamily
AYN53_RS11460	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AYN53_RS11490	COG1376	ErfK ybiS ycfS ynhG family protein
AYN53_RS11560	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AYN53_RS11575	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
AYN53_RS11585	COG1012	belongs to the aldehyde dehydrogenase family
AYN53_RS11590	COG1012	belongs to the aldehyde dehydrogenase family
AYN53_RS11590	COG1454	alcohol dehydrogenase
AYN53_RS11595	COG4656	Part of a membrane complex involved in electron transport
AYN53_RS11620	COG1289	transmembrane transporter activity
AYN53_RS11630	COG1686	Belongs to the peptidase S11 family
AYN53_RS11635	COG2925	Exonuclease
AYN53_RS11640	COG0531	amino acid
AYN53_RS11650	COG0583	DNA-binding transcription factor activity
AYN53_RS11655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AYN53_RS11670	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AYN53_RS11680	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AYN53_RS11680	COG0131	Imidazoleglycerol-phosphate dehydratase
AYN53_RS11685	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AYN53_RS11705	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
AYN53_RS11710	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AYN53_RS11715	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AYN53_RS11720	COG0438	transferase activity, transferring glycosyl groups
AYN53_RS11775	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AYN53_RS11780	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AYN53_RS11785	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AYN53_RS11795	COG1088	dTDP-glucose 4,6-dehydratase activity
AYN53_RS11800	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AYN53_RS11810	COG1253	flavin adenine dinucleotide binding
AYN53_RS11815	COG2982	Protein involved in outer membrane biogenesis
AYN53_RS11825	COG0572	uridine kinase
AYN53_RS11830	COG3447	MASE1 domain protein
AYN53_RS11830	COG5002	protein histidine kinase activity
AYN53_RS11830	COG5001	Diguanylate cyclase
AYN53_RS11835	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AYN53_RS11840	COG0443	Heat shock 70 kDa protein
AYN53_RS11900	COG5301	cellulose 1,4-beta-cellobiosidase activity
AYN53_RS11965	COG4220	transposase activity
AYN53_RS11970	COG3646	Phage regulatory protein
AYN53_RS11980	COG3772	lysozyme
AYN53_RS12060	COG2205	protein histidine kinase activity
AYN53_RS12065	COG0745	RESPONSE REGULATOR receiver
AYN53_RS12075	COG0826	peptidase U32
AYN53_RS12100	COG1830	Aldolase
AYN53_RS12105	COG2211	Major facilitator Superfamily
AYN53_RS12110	COG1397	ADP-ribosylglycohydrolase
AYN53_RS12115	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AYN53_RS12120	COG2188	Transcriptional regulator
AYN53_RS12140	COG3757	hydrolase, family 25
AYN53_RS12145	COG0351	phosphomethylpyrimidine kinase
AYN53_RS12165	COG5455	response to cobalt ion
AYN53_RS12170	COG3539	Fimbrial protein
AYN53_RS12180	COG3121	Chaperone
AYN53_RS12185	COG3539	Fimbrial protein
AYN53_RS12195	COG0489	protein tyrosine kinase activity
AYN53_RS12210	COG3831	ATPase activity
AYN53_RS12225	COG2425	protein containing a von Willebrand factor type A (vWA) domain
AYN53_RS12230	COG3552	Protein containing von Willebrand factor type A (VWA) domain
AYN53_RS12235	COG4715	Zinc finger, swim domain protein
AYN53_RS12240	COG4808	Protein conserved in bacteria
AYN53_RS12245	COG4807	Protein conserved in bacteria
AYN53_RS12250	COG3279	Response regulator of the LytR AlgR family
AYN53_RS12255	COG3275	phosphorelay sensor kinase activity
AYN53_RS12260	COG0789	Transcriptional regulator
AYN53_RS12270	COG1174	glycine betaine transport
AYN53_RS12275	COG1125	glycine betaine transport
AYN53_RS12280	COG1174	glycine betaine transport
AYN53_RS12285	COG1732	Glycine betaine
AYN53_RS12290	COG1472	Belongs to the glycosyl hydrolase 3 family
AYN53_RS12295	COG0277	FAD linked oxidase domain protein
AYN53_RS12300	COG1686	Belongs to the peptidase S11 family
AYN53_RS12310	COG0586	Pfam SNARE associated Golgi protein
AYN53_RS12320	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AYN53_RS12330	COG1346	cytolysis
AYN53_RS12340	COG2949	membrane
AYN53_RS12355	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AYN53_RS12355	COG0167	dihydroorotate dehydrogenase activity
AYN53_RS12360	COG4211	Belongs to the binding-protein-dependent transport system permease family
AYN53_RS12365	COG1129	ABC transporter
AYN53_RS12370	COG1879	ABC-type sugar transport system periplasmic component
AYN53_RS12375	COG1609	Transcriptional regulator
AYN53_RS12380	COG2311	Membrane
AYN53_RS12395	COG4771	TonB-dependent receptor
AYN53_RS12400	COG0833	amino acid
AYN53_RS12405	COG0583	DNA-binding transcription factor activity
AYN53_RS12410	COG2855	membrane
AYN53_RS12420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AYN53_RS12420	COG1522	sequence-specific DNA binding
AYN53_RS12425	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AYN53_RS12430	COG2313	pseudouridylate synthase activity
AYN53_RS12435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AYN53_RS12440	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AYN53_RS12440	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AYN53_RS12440	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AYN53_RS12445	COG1105	Belongs to the carbohydrate kinase PfkB family
AYN53_RS12450	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN53_RS12450	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN53_RS12455	COG2814	Major facilitator Superfamily
AYN53_RS12470	COG0246	Mannitol dehydrogenase
AYN53_RS12475	COG0523	cobalamin synthesis protein
AYN53_RS12480	COG0671	phosphoesterase, PA-phosphatase related
AYN53_RS12485	COG0791	NLP P60 protein
AYN53_RS12490	COG2200	EAL domain
AYN53_RS12495	COG4166	transmembrane transport
AYN53_RS12500	COG4174	ABC transporter (Permease)
AYN53_RS12505	COG4239	(ABC) transporter, permease
AYN53_RS12510	COG4172	Belongs to the ABC transporter superfamily
AYN53_RS12525	COG2814	Major facilitator Superfamily
AYN53_RS12530	COG1187	pseudouridine synthase activity
AYN53_RS12535	COG1061	Type III restriction enzyme res subunit
AYN53_RS12550	COG1053	succinate dehydrogenase
AYN53_RS12550	COG0431	NADPH-dependent FMN reductase
AYN53_RS12550	COG3976	FMN-binding domain protein
AYN53_RS12555	COG3005	denitrification pathway
AYN53_RS12570	COG3083	sulfuric ester hydrolase activity
AYN53_RS12580	COG0582	viral genome integration into host DNA
AYN53_RS12620	COG3468	outer membrane autotransporter barrel domain protein
AYN53_RS12625	COG2197	response regulator
AYN53_RS12630	COG4235	cytochrome complex assembly
AYN53_RS12630	COG3088	subunit of a heme lyase
AYN53_RS12635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AYN53_RS12640	COG1138	Cytochrome C-type biogenesis protein
AYN53_RS12650	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AYN53_RS12655	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AYN53_RS12660	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AYN53_RS12665	COG4133	protoheme IX ABC transporter activity
AYN53_RS12670	COG3005	denitrification pathway
AYN53_RS12675	COG3043	anaerobic respiration
AYN53_RS12680	COG0348	domain, Protein
AYN53_RS12685	COG0437	4 iron, 4 sulfur cluster binding
AYN53_RS12695	COG3062	negative regulation of establishment of protein localization
AYN53_RS12700	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
AYN53_RS12700	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AYN53_RS12715	COG4615	Cyclic peptide transporter
AYN53_RS12720	COG3145	DNA-N1-methyladenine dioxygenase activity
AYN53_RS12730	COG1477	protein flavinylation
AYN53_RS12740	COG0642	Histidine kinase
AYN53_RS12740	COG2198	Histidine kinase
AYN53_RS12745	COG2197	response regulator
AYN53_RS12750	COG0784	Response regulator, receiver
AYN53_RS12750	COG2205	protein histidine kinase activity
AYN53_RS12760	COG4676	Protein conserved in bacteria
AYN53_RS12765	COG5445	Predicted secreted protein (DUF2300)
AYN53_RS12775	COG3234	Protein of unknown function (DUF1175)
AYN53_RS12780	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
AYN53_RS12785	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AYN53_RS12795	COG3468	outer membrane autotransporter barrel domain protein
AYN53_RS12800	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AYN53_RS12805	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AYN53_RS12810	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AYN53_RS12815	COG2814	Major facilitator Superfamily
AYN53_RS12820	COG0583	DNA-binding transcription factor activity
AYN53_RS12825	COG0584	glycerophosphoryl diester phosphodiesterase
AYN53_RS12830	COG2271	Major facilitator Superfamily
AYN53_RS12835	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AYN53_RS12845	COG0247	lactate metabolic process
AYN53_RS12850	COG5464	transposase or invertase
AYN53_RS12860	COG2271	Major facilitator Superfamily
AYN53_RS12870	COG1414	Transcriptional regulator
AYN53_RS12935	COG0318	PFAM AMP-dependent synthetase and ligase
AYN53_RS12945	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AYN53_RS12960	COG1169	isochorismate synthase
AYN53_RS12965	COG4575	ribosome binding
AYN53_RS12970	COG2153	protein acetylation
AYN53_RS12980	COG2304	oxidoreductase activity
AYN53_RS12985	COG2234	aminopeptidase activity
AYN53_RS13000	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AYN53_RS13005	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AYN53_RS13015	COG0839	Belongs to the complex I subunit 6 family
AYN53_RS13030	COG1034	ATP synthesis coupled electron transport
AYN53_RS13035	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AYN53_RS13040	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AYN53_RS13060	COG0583	DNA-binding transcription factor activity
AYN53_RS13065	COG0436	Aminotransferase
AYN53_RS13075	COG0471	metal ion transport
AYN53_RS13075	COG0490	domain, Protein
AYN53_RS13080	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AYN53_RS13095	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AYN53_RS13100	COG0280	phosphate acetyltransferase
AYN53_RS13100	COG0857	belongs to the CobB CobQ family
AYN53_RS13105	COG1288	antiporter activity
AYN53_RS13110	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AYN53_RS13115	COG3959	Transketolase, thiamine diphosphate binding domain
AYN53_RS13120	COG3037	sugar-specific permease SgaT UlaA
AYN53_RS13130	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN53_RS13135	COG1609	Transcriptional regulator
AYN53_RS13140	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AYN53_RS13145	COG0622	Phosphoesterase
AYN53_RS13155	COG0625	glutathione transferase activity
AYN53_RS13160	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AYN53_RS13165	COG1090	epimerase
AYN53_RS13170	COG5464	transposase or invertase
AYN53_RS13175	COG4598	ABC transporter
AYN53_RS13180	COG4160	amino acid transport
AYN53_RS13185	COG4215	(ABC) transporter
AYN53_RS13190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AYN53_RS13195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AYN53_RS13200	COG0163	prenyltransferase activity
AYN53_RS13205	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AYN53_RS13210	COG1286	toxin biosynthetic process
AYN53_RS13215	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AYN53_RS13220	COG0285	dihydrofolate synthase activity
AYN53_RS13230	COG0586	Pfam SNARE associated Golgi protein
AYN53_RS13240	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AYN53_RS13255	COG2814	Major facilitator Superfamily
AYN53_RS13260	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AYN53_RS13275	COG3101	peptidyl-lysine hydroxylation
AYN53_RS13280	COG0730	response to heat
AYN53_RS13315	COG3539	Fimbrial protein
AYN53_RS13320	COG3539	Fimbrial protein
AYN53_RS13325	COG3539	Fimbrial protein
AYN53_RS13335	COG2062	phosphohistidine phosphatase, SixA
AYN53_RS13340	COG1024	Enoyl-CoA hydratase
AYN53_RS13340	COG1250	3-hydroxyacyl-CoA dehydrogenase
AYN53_RS13350	COG3691	Protein conserved in bacteria
AYN53_RS13355	COG2067	long-chain fatty acid transport protein
AYN53_RS13360	COG2853	Lipoprotein
AYN53_RS13370	COG0582	viral genome integration into host DNA
AYN53_RS13475	COG1783	phage Terminase large subunit
AYN53_RS13495	COG3646	Phage regulatory protein
AYN53_RS13620	COG4712	double-strand break repair protein
AYN53_RS13675	COG0583	DNA-binding transcription factor activity
AYN53_RS13680	COG2610	gluconate transmembrane transporter activity
AYN53_RS13695	COG1560	Kdo2-lipid A biosynthetic process
AYN53_RS13705	COG0436	Aminotransferase
AYN53_RS13710	COG3275	phosphorelay sensor kinase activity
AYN53_RS13715	COG3279	Response regulator of the LytR AlgR family
AYN53_RS13720	COG2207	Transcriptional regulator
AYN53_RS13725	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN53_RS13725	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN53_RS13725	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AYN53_RS13730	COG1363	Peptidase, m42
AYN53_RS13735	COG0006	proline dipeptidase activity
AYN53_RS13740	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AYN53_RS13745	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AYN53_RS13770	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AYN53_RS13775	COG2199	diguanylate cyclase activity
AYN53_RS13775	COG2200	EAL domain
AYN53_RS13790	COG3415	Transposase
AYN53_RS13795	COG3415	Transposase
AYN53_RS13820	COG0583	DNA-binding transcription factor activity
AYN53_RS13825	COG2211	Major facilitator Superfamily
AYN53_RS13830	COG2211	Major facilitator Superfamily
AYN53_RS13835	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AYN53_RS13845	COG2211	Major facilitator Superfamily
AYN53_RS13850	COG0385	Bile acid
AYN53_RS13875	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AYN53_RS13880	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN53_RS13885	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AYN53_RS13890	COG2190	(PTS) system
AYN53_RS13905	COG3831	ATPase activity
AYN53_RS13905	COG4884	unkown
AYN53_RS13915	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AYN53_RS13920	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AYN53_RS13925	COG4208	sulfate ABC transporter
AYN53_RS13930	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AYN53_RS13935	COG4150	thiosulfate binding
AYN53_RS13940	COG1028	Short-chain dehydrogenase reductase Sdr
AYN53_RS13960	COG2837	iron assimilation
AYN53_RS13980	COG0860	N-Acetylmuramoyl-L-alanine amidase
AYN53_RS14000	COG2207	Transcriptional regulator
AYN53_RS14005	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AYN53_RS14010	COG4816	utilization protein
AYN53_RS14020	COG4303	Ethanolamine ammonia lyase large subunit
AYN53_RS14035	COG1454	alcohol dehydrogenase
AYN53_RS14040	COG4820	ethanolamine utilization protein (EutJ)
AYN53_RS14045	COG1012	belongs to the aldehyde dehydrogenase family
AYN53_RS14050	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
AYN53_RS14055	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AYN53_RS14060	COG0280	phosphate acetyltransferase
AYN53_RS14065	COG4812	Cobalamin adenosyltransferase
AYN53_RS14075	COG4917	ethanolamine utilization protein
AYN53_RS14080	COG4810	utilization protein
AYN53_RS14085	COG0280	phosphate acetyltransferase
AYN53_RS14085	COG0281	malic enzyme
AYN53_RS14095	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AYN53_RS14100	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AYN53_RS14110	COG0493	'glutamate synthase
AYN53_RS14110	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AYN53_RS14115	COG3850	Histidine kinase
AYN53_RS14120	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AYN53_RS14130	COG1393	Belongs to the ArsC family
AYN53_RS14145	COG0400	carboxylic ester hydrolase activity
AYN53_RS14150	COG1444	tRNA N-acetyltransferase activity
AYN53_RS14155	COG2321	neutral zinc metallopeptidase
AYN53_RS14165	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AYN53_RS14175	COG2716	regulation of RNA biosynthetic process
AYN53_RS14180	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AYN53_RS14185	COG0628	permease
AYN53_RS14190	COG4783	chaperone-mediated protein folding
AYN53_RS14195	COG1393	Belongs to the ArsC family
AYN53_RS14205	COG2233	PERMEase
AYN53_RS14220	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AYN53_RS14225	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AYN53_RS14230	COG0248	Ppx GppA phosphatase
AYN53_RS14235	COG2200	EAL domain
AYN53_RS14245	COG3133	Outer membrane lipoprotein
AYN53_RS14260	COG0516	GMP reductase activity
AYN53_RS14260	COG0517	IMP dehydrogenase activity
AYN53_RS14285	COG1645	bacterial-type flagellum-dependent swarming motility
AYN53_RS14300	COG2976	Protein conserved in bacteria
AYN53_RS14330	COG4953	penicillin-binding protein 1C
AYN53_RS14335	COG2373	Large extracellular alpha-helical protein
AYN53_RS14340	COG2897	thiosulfate sulfurtransferase activity
AYN53_RS14355	COG2975	iron-sulfur cluster assembly
AYN53_RS14360	COG0633	Ferredoxin
AYN53_RS14380	COG0822	iron-sulfur transferase activity
AYN53_RS14400	COG0483	inositol monophosphate 1-phosphatase activity
AYN53_RS14405	COG1073	alpha beta
AYN53_RS14410	COG3711	transcriptional antiterminator
AYN53_RS14415	COG2814	Major facilitator Superfamily
AYN53_RS14425	COG2259	Doxx family
AYN53_RS14430	COG2017	converts alpha-aldose to the beta-anomer
AYN53_RS14435	COG1063	alcohol dehydrogenase
AYN53_RS14440	COG1172	Belongs to the binding-protein-dependent transport system permease family
AYN53_RS14445	COG1129	ABC transporter
AYN53_RS14450	COG1879	ABC-type sugar transport system periplasmic component
AYN53_RS14455	COG0457	Tetratricopeptide repeat
AYN53_RS14460	COG1940	carbohydrate kinase activity
AYN53_RS14470	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AYN53_RS14470	COG1017	nitric oxide dioxygenase activity
AYN53_RS14475	COG0347	Belongs to the P(II) protein family
AYN53_RS14480	COG2204	response regulator
AYN53_RS14485	COG3170	Tfp pilus assembly protein FimV
AYN53_RS14490	COG2205	protein histidine kinase activity
AYN53_RS14500	COG0047	phosphoribosylformylglycinamidine synthase activity
AYN53_RS14500	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AYN53_RS14515	COG0560	Phosphoserine phosphatase
AYN53_RS14520	COG1737	Transcriptional regulator
AYN53_RS14525	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AYN53_RS14540	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AYN53_RS14560	COG0681	Belongs to the peptidase S26 family
AYN53_RS14570	COG3086	response to oxidative stress
AYN53_RS14575	COG3026	antisigma factor binding
AYN53_RS14580	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
AYN53_RS14585	COG1595	DNA-templated transcription, initiation
AYN53_RS14595	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AYN53_RS14605	COG0513	Belongs to the DEAD box helicase family
AYN53_RS14610	COG0583	DNA-binding transcription factor activity
AYN53_RS14640	COG2271	Major facilitator Superfamily
AYN53_RS14650	COG1960	acyl-CoA dehydrogenase activity
AYN53_RS14655	COG2086	electron transfer activity
AYN53_RS14660	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AYN53_RS14675	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AYN53_RS14680	COG3118	belongs to the thioredoxin family
AYN53_RS14685	COG3148	PFAM DTW domain containing protein
AYN53_RS14690	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AYN53_RS14690	COG1042	CoA-binding domain protein
AYN53_RS14690	COG0045	succinate-CoA ligase (ADP-forming) activity
AYN53_RS14695	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AYN53_RS14700	COG5544	Lipoprotein
AYN53_RS14705	COG0477	Major facilitator Superfamily
AYN53_RS14735	COG0542	response to heat
AYN53_RS14745	COG0564	pseudouridine synthase activity
AYN53_RS14750	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AYN53_RS14755	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AYN53_RS14765	COG0077	Prephenate dehydratase
AYN53_RS14765	COG1605	Chorismate mutase
AYN53_RS14770	COG1605	Chorismate mutase
AYN53_RS14770	COG0287	Prephenate dehydrogenase
AYN53_RS14775	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AYN53_RS14790	COG2199	diguanylate cyclase activity
AYN53_RS14795	COG2885	chlorophyll binding
AYN53_RS14820	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AYN53_RS14825	COG4137	Cytochrome C assembly protein
AYN53_RS14830	COG4536	flavin adenine dinucleotide binding
AYN53_RS14850	COG0497	DNA recombination
AYN53_RS14855	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AYN53_RS14865	COG2867	negative regulation of translational initiation
AYN53_RS14925	COG0727	PFAM Uncharacterised protein family (UPF0153)
AYN53_RS14960	COG5301	cellulose 1,4-beta-cellobiosidase activity
AYN53_RS15075	COG3772	lysozyme
AYN53_RS15120	COG0305	Participates in initiation and elongation during chromosome replication
AYN53_RS15125	COG1484	DNA-dependent DNA replication
AYN53_RS15155	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AYN53_RS15215	COG0582	viral genome integration into host DNA
AYN53_RS15245	COG0366	Alpha amylase catalytic
AYN53_RS15255	COG0579	oxidoreductase
AYN53_RS15260	COG1012	belongs to the aldehyde dehydrogenase family
AYN53_RS15265	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AYN53_RS15270	COG1113	amino acid transport
AYN53_RS15275	COG1802	Transcriptional regulator
AYN53_RS15280	COG0401	homolog of Blt101
AYN53_RS15285	COG0640	Transcriptional regulator
AYN53_RS15290	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AYN53_RS15295	COG2916	Histone family protein nucleoid-structuring protein H-NS
AYN53_RS15310	COG4575	ribosome binding
AYN53_RS15320	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AYN53_RS15330	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AYN53_RS15340	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AYN53_RS15345	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AYN53_RS15355	COG4175	Glycine betaine
AYN53_RS15360	COG4176	ABC-type proline glycine betaine transport system permease component
AYN53_RS15365	COG2113	Glycine betaine
AYN53_RS15370	COG2814	Major facilitator Superfamily
AYN53_RS15375	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AYN53_RS15385	COG1846	Transcriptional regulator
AYN53_RS15390	COG1566	PFAM secretion protein HlyD family protein
AYN53_RS15395	COG2814	Major facilitator Superfamily
AYN53_RS15415	COG1238	metal cluster binding
AYN53_RS15420	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AYN53_RS15450	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AYN53_RS15470	COG1546	Belongs to the CinA family
AYN53_RS15475	COG2951	lytic endotransglycosylase activity
AYN53_RS15480	COG3730	PTS system glucitol sorbitol-specific
AYN53_RS15485	COG3732	PTS system glucitol sorbitol-specific
AYN53_RS15495	COG1028	Short-chain dehydrogenase reductase Sdr
AYN53_RS15500	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN53_RS15505	COG1349	DNA-binding transcription factor activity
AYN53_RS15510	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AYN53_RS15510	COG0517	IMP dehydrogenase activity
AYN53_RS15515	COG3604	Transcriptional regulator
AYN53_RS15530	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AYN53_RS15535	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AYN53_RS15545	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AYN53_RS15555	COG3260	NADH ubiquinone oxidoreductase 20
AYN53_RS15560	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AYN53_RS15565	COG3261	NADH dehydrogenase
AYN53_RS15565	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AYN53_RS15570	COG0650	Formate hydrogenlyase subunit 4
AYN53_RS15575	COG0651	ATP synthesis coupled electron transport
AYN53_RS15580	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AYN53_RS15590	COG0375	protein maturation
AYN53_RS15595	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AYN53_RS15600	COG0298	carbon dioxide binding
AYN53_RS15605	COG0409	Hydrogenase expression formation protein
AYN53_RS15610	COG0309	Hydrogenase expression formation protein (HypE)
AYN53_RS15615	COG3604	Transcriptional regulator
AYN53_RS15640	COG1349	DNA-binding transcription factor activity
AYN53_RS15645	COG2084	Dehydrogenase
AYN53_RS15650	COG3395	kinase activity
AYN53_RS15655	COG0235	Class ii aldolase
AYN53_RS15660	COG3622	Belongs to the hyi family
AYN53_RS15665	COG2610	gluconate transmembrane transporter activity
AYN53_RS15675	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AYN53_RS15680	COG0163	prenyltransferase activity
AYN53_RS15690	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AYN53_RS15695	COG1388	LysM domain
AYN53_RS15695	COG4942	peptidase
AYN53_RS15710	COG0585	pseudouridine synthase activity
AYN53_RS15750	COG2234	aminopeptidase activity
AYN53_RS15755	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AYN53_RS15760	COG1518	maintenance of DNA repeat elements
AYN53_RS15775	COG1857	crispr-associated protein
AYN53_RS15790	COG1203	CRISPR-associated helicase, Cas3
AYN53_RS15795	COG3385	transposase activity
AYN53_RS15830	COG0720	synthase
AYN53_RS15835	COG0644	oxidoreductase
AYN53_RS15840	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AYN53_RS15845	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AYN53_RS15850	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AYN53_RS15855	COG2086	electron transfer activity
AYN53_RS15860	COG0477	Major facilitator Superfamily
AYN53_RS15865	COG0277	FAD linked oxidase domain protein
AYN53_RS15875	COG2223	nitrite transmembrane transporter activity
AYN53_RS15880	COG1070	Carbohydrate kinase
AYN53_RS15885	COG0602	queuosine metabolic process
AYN53_RS15895	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AYN53_RS15905	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AYN53_RS15920	COG3956	TIGRFAM MazG family protein
AYN53_RS15925	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AYN53_RS15930	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AYN53_RS15935	COG3437	response regulator, receiver
AYN53_RS15935	COG3850	Histidine kinase
AYN53_RS15935	COG4999	Histidine kinase
AYN53_RS15935	COG2205	protein histidine kinase activity
AYN53_RS15940	COG0716	FMN binding
AYN53_RS15945	COG0564	pseudouridine synthase activity
AYN53_RS15950	COG3098	single-species biofilm formation
AYN53_RS15965	COG1611	Belongs to the LOG family
AYN53_RS15970	COG0814	amino acid
AYN53_RS15975	COG1760	l-serine dehydratase
AYN53_RS15990	COG0235	Class ii aldolase
AYN53_RS15995	COG0738	Major facilitator superfamily
AYN53_RS16005	COG1070	Carbohydrate kinase
AYN53_RS16015	COG1349	DNA-binding transcription factor activity
AYN53_RS16025	COG2363	Small membrane protein
AYN53_RS16030	COG0583	DNA-binding transcription factor activity
AYN53_RS16040	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AYN53_RS16045	COG2166	iron-sulfur cluster assembly
AYN53_RS16050	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AYN53_RS16055	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AYN53_RS16075	COG0860	N-Acetylmuramoyl-L-alanine amidase
AYN53_RS16080	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AYN53_RS16080	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AYN53_RS16085	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AYN53_RS16090	COG1074	ATP-dependent DNA helicase activity
AYN53_RS16095	COG1025	Belongs to the peptidase M16 family
AYN53_RS16100	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AYN53_RS16105	COG4967	type IV pilus modification protein PilV
AYN53_RS16115	COG4795	General secretion pathway protein
AYN53_RS16120	COG2165	general secretion pathway protein
AYN53_RS16135	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
AYN53_RS16150	COG0861	Integral membrane protein TerC family
AYN53_RS16160	COG0667	Aldo Keto reductase
AYN53_RS16180	COG1609	Transcriptional regulator
AYN53_RS16190	COG0583	DNA-binding transcription factor activity
AYN53_RS16200	COG0183	Belongs to the thiolase family
AYN53_RS16205	COG0814	amino acid
AYN53_RS16210	COG2771	luxR family
AYN53_RS16230	COG0457	Tetratricopeptide repeat
AYN53_RS16235	COG3710	Transcriptional regulator
AYN53_RS16235	COG0457	Tetratricopeptide repeat
AYN53_RS16245	COG0741	lytic transglycosylase activity
AYN53_RS16250	COG2197	response regulator
AYN53_RS16355	COG2207	Transcriptional regulator
AYN53_RS16365	COG3387	PFAM Glycoside hydrolase 15-related
AYN53_RS16375	COG4942	peptidase
AYN53_RS16380	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AYN53_RS16385	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AYN53_RS16390	COG2080	2 iron, 2 sulfur cluster binding
AYN53_RS16395	COG3829	transcription factor binding
AYN53_RS16400	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AYN53_RS16405	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AYN53_RS16410	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AYN53_RS16420	COG0549	Belongs to the carbamate kinase family
AYN53_RS16425	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AYN53_RS16425	COG3608	succinylglutamate desuccinylase aspartoacylase
AYN53_RS16430	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AYN53_RS16435	COG2068	MobA-Related Protein
AYN53_RS16440	COG0493	'glutamate synthase
AYN53_RS16440	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AYN53_RS16445	COG0402	S-adenosylhomocysteine deaminase activity
AYN53_RS16450	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AYN53_RS16455	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AYN53_RS16455	COG2080	2 iron, 2 sulfur cluster binding
AYN53_RS16460	COG2233	PERMEase
AYN53_RS16465	COG0402	S-adenosylhomocysteine deaminase activity
AYN53_RS16470	COG2252	PERMEase
AYN53_RS16475	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AYN53_RS16480	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AYN53_RS16480	COG0493	'glutamate synthase
AYN53_RS16485	COG2233	PERMEase
AYN53_RS16495	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AYN53_RS16500	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AYN53_RS16510	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AYN53_RS16515	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AYN53_RS16520	COG4974	Belongs to the 'phage' integrase family
AYN53_RS16525	COG0716	FMN binding
AYN53_RS16535	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AYN53_RS16550	COG1272	protein, Hemolysin III
AYN53_RS16560	COG2723	6-phospho-beta-galactosidase activity
AYN53_RS16595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AYN53_RS16600	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AYN53_RS16605	COG0006	proline dipeptidase activity
AYN53_RS16625	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AYN53_RS16630	COG1454	alcohol dehydrogenase
AYN53_RS16635	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN53_RS16655	COG3414	Phosphotransferase system galactitol-specific IIB component
AYN53_RS16670	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AYN53_RS16690	COG0583	DNA-binding transcription factor activity
AYN53_RS16695	COG2968	Membrane
AYN53_RS16700	COG1279	arginine transmembrane transporter activity
AYN53_RS16710	COG0668	transmembrane transport
AYN53_RS16715	COG0191	fructose-bisphosphate aldolase activity
AYN53_RS16730	COG1072	(Pantothenic acid kinase))
AYN53_RS16740	COG1494	fructose-1,6-bisphosphatase
AYN53_RS16745	COG1063	alcohol dehydrogenase
AYN53_RS16750	COG2213	PTS system mannitol-specific
AYN53_RS16755	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN53_RS16760	COG0330	HflC and HflK could
AYN53_RS16765	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AYN53_RS16770	COG0501	Belongs to the peptidase M48B family
AYN53_RS16795	COG4948	Mandelate Racemase Muconate Lactonizing
AYN53_RS16805	COG1028	Short-chain dehydrogenase reductase Sdr
AYN53_RS16810	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AYN53_RS16815	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AYN53_RS16825	COG1166	arginine decarboxylase activity
AYN53_RS16850	COG2814	Major facilitator Superfamily
AYN53_RS16860	COG2356	endonuclease I
AYN53_RS16865	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AYN53_RS16870	COG0189	ligase activity
AYN53_RS16885	COG2805	Type II/IV secretion system protein
AYN53_RS16890	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AYN53_RS16895	COG0762	integral membrane protein
AYN53_RS16910	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AYN53_RS16920	COG0252	asparaginase activity
AYN53_RS16930	COG3171	Protein conserved in bacteria
AYN53_RS16940	COG1194	a g-specific adenine glycosylase
AYN53_RS16955	COG2211	Major facilitator Superfamily
AYN53_RS16960	COG1982	Orn Lys Arg decarboxylase major
AYN53_RS16965	COG1811	Na channel or pump
AYN53_RS16980	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AYN53_RS16995	COG0583	DNA-binding transcription factor activity
AYN53_RS17000	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AYN53_RS17030	COG2165	general secretion pathway protein
AYN53_RS17035	COG1459	type II secretion system
AYN53_RS17040	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AYN53_RS17050	COG3031	protein transport across the cell outer membrane
AYN53_RS17060	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AYN53_RS17070	COG3064	Membrane
AYN53_RS17075	COG1620	l-lactate permease
AYN53_RS17080	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AYN53_RS17085	COG3193	protein, possibly involved in utilization of glycolate and propanediol
AYN53_RS17090	COG0247	lactate metabolic process
AYN53_RS17095	COG0277	FAD linked oxidase domain protein
AYN53_RS17100	COG0277	FAD linked oxidase domain protein
AYN53_RS17105	COG2186	Transcriptional regulator
AYN53_RS17110	COG0456	acetyltransferase
AYN53_RS17115	COG0318	PFAM AMP-dependent synthetase and ligase
AYN53_RS17125	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AYN53_RS17130	COG0156	8-amino-7-oxononanoate synthase activity
AYN53_RS17140	COG0795	lipopolysaccharide-transporting ATPase activity
AYN53_RS17145	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AYN53_RS17155	COG2244	polysaccharide biosynthetic process
AYN53_RS17160	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AYN53_RS17165	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AYN53_RS17170	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AYN53_RS17175	COG0306	phosphate transporter
AYN53_RS17180	COG0754	glutathionylspermidine amidase activity
AYN53_RS17185	COG0625	glutathione transferase activity
AYN53_RS17190	COG0298	carbon dioxide binding
AYN53_RS17200	COG1773	rubredoxin
AYN53_RS17205	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AYN53_RS17210	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AYN53_RS17215	COG5557	Pfam Polysulphide reductase, NrfD
AYN53_RS17220	COG0437	4 iron, 4 sulfur cluster binding
AYN53_RS17225	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AYN53_RS17230	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AYN53_RS17235	COG0644	oxidoreductase
AYN53_RS17240	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AYN53_RS17245	COG2086	electron transfer activity
AYN53_RS17250	COG1960	acyl-CoA dehydrogenase activity
AYN53_RS17255	COG2610	gluconate transmembrane transporter activity
AYN53_RS17270	COG1924	4 iron, 4 sulfur cluster binding
AYN53_RS17280	COG0318	PFAM AMP-dependent synthetase and ligase
AYN53_RS17285	COG4977	sequence-specific DNA binding
AYN53_RS17295	COG0667	Aldo Keto reductase
AYN53_RS17300	COG0848	biopolymer transport protein
AYN53_RS17305	COG0811	peptide transport
AYN53_RS17310	COG0626	cystathionine gamma-synthase activity
AYN53_RS17315	COG0586	Pfam SNARE associated Golgi protein
AYN53_RS17320	COG2207	Transcriptional regulator
AYN53_RS17325	COG1979	alcohol dehydrogenase
AYN53_RS17330	COG0656	L-ascorbic acid biosynthetic process
AYN53_RS17335	COG0471	metal ion transport
AYN53_RS17355	COG4238	major outer membrane lipoprotein
AYN53_RS17360	COG1032	radical SAM domain protein
AYN53_RS17365	COG2186	Transcriptional regulator
AYN53_RS17370	COG0246	Mannitol dehydrogenase
AYN53_RS17375	COG1063	alcohol dehydrogenase
AYN53_RS17380	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AYN53_RS17415	COG2132	Multicopper oxidase
AYN53_RS17420	COG0204	Acyl-transferase
AYN53_RS17425	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AYN53_RS17430	COG4166	transmembrane transport
AYN53_RS17435	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AYN53_RS17440	COG3111	PFAM Bacterial OB fold (BOF) protein
AYN53_RS17445	COG0745	RESPONSE REGULATOR receiver
AYN53_RS17450	COG0642	Histidine kinase
AYN53_RS17455	COG2249	NAD(P)H dehydrogenase (quinone) activity
AYN53_RS17460	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AYN53_RS17465	COG0187	DNA topoisomerase II activity
AYN53_RS17470	COG3150	esterase
AYN53_RS17475	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AYN53_RS17480	COG3151	Protein conserved in bacteria
AYN53_RS17485	COG0494	nUDIX hydrolase
AYN53_RS17490	COG1538	Outer membrane efflux protein
AYN53_RS17500	COG0754	glutathionylspermidine amidase activity
AYN53_RS17510	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AYN53_RS17520	COG3384	dioxygenase
AYN53_RS17535	COG2960	long-chain fatty acid transporting porin activity
AYN53_RS17545	COG1585	Membrane protein implicated in regulation of membrane protease activity
AYN53_RS17580	COG3025	triphosphatase activity
AYN53_RS17585	COG4991	sh3 domain protein
AYN53_RS17600	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AYN53_RS17620	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AYN53_RS17625	COG0471	metal ion transport
AYN53_RS17635	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AYN53_RS17640	COG0358	DNA primase activity
AYN53_RS17645	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AYN53_RS17660	COG2375	cellular response to nickel ion
AYN53_RS17670	COG1695	Transcriptional regulator
AYN53_RS17680	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AYN53_RS17685	COG1609	Transcriptional regulator
AYN53_RS17690	COG3250	beta-galactosidase activity
AYN53_RS17695	COG2731	YhcH YjgK YiaL family protein
AYN53_RS17700	COG0531	amino acid
AYN53_RS17710	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
AYN53_RS17710	COG3408	Glycogen debranching enzyme
AYN53_RS17715	COG0446	pyridine nucleotide-disulphide oxidoreductase
AYN53_RS17715	COG1902	pentaerythritol trinitrate reductase activity
AYN53_RS17725	COG1451	nucleotide metabolic process
AYN53_RS17730	COG2949	membrane
AYN53_RS17735	COG0673	inositol 2-dehydrogenase activity
AYN53_RS17745	COG0861	Integral membrane protein TerC family
AYN53_RS17750	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AYN53_RS17760	COG2721	sulfolactate sulfo-lyase activity
AYN53_RS17770	COG2271	Major facilitator Superfamily
AYN53_RS17795	COG2186	Transcriptional regulator
AYN53_RS17800	COG0586	Pfam SNARE associated Golgi protein
AYN53_RS17810	COG1422	Protein of unknown function (DUF1090)
AYN53_RS17815	COG4575	ribosome binding
AYN53_RS17820	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
AYN53_RS17830	COG2259	Doxx family
AYN53_RS17840	COG0435	Glutathione S-transferase
AYN53_RS17845	COG3152	Membrane
AYN53_RS17850	COG0583	DNA-binding transcription factor activity
AYN53_RS17855	COG1741	Belongs to the pirin family
AYN53_RS17870	COG0814	amino acid
AYN53_RS17880	COG1760	l-serine dehydratase
AYN53_RS17885	COG0251	oxidation-reduction process
AYN53_RS17890	COG1882	Formate acetyltransferase
AYN53_RS17895	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AYN53_RS17905	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AYN53_RS17910	COG0583	DNA-binding transcription factor activity
AYN53_RS17930	COG1929	Belongs to the glycerate kinase type-1 family
AYN53_RS17935	COG2084	Dehydrogenase
AYN53_RS17945	COG2271	Major facilitator Superfamily
AYN53_RS17950	COG2721	sulfolactate sulfo-lyase activity
AYN53_RS17955	COG1349	DNA-binding transcription factor activity
AYN53_RS17965	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AYN53_RS17975	COG3716	PTS system mannose fructose sorbose family IID component
AYN53_RS17985	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AYN53_RS18005	COG2222	sugar isomerase
AYN53_RS18020	COG3715	PTS system
AYN53_RS18025	COG3716	PTS system mannose fructose sorbose family IID component
AYN53_RS18035	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AYN53_RS18040	COG3107	peptidoglycan biosynthetic process
AYN53_RS18055	COG2823	Periplasmic or secreted lipoprotein
AYN53_RS18060	COG0702	epimerase
AYN53_RS18075	COG3153	acetyltransferase
AYN53_RS18080	COG3154	lipid carrier protein
AYN53_RS18085	COG0826	peptidase U32
AYN53_RS18090	COG0826	peptidase U32
AYN53_RS18095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AYN53_RS18100	COG3034	peptidoglycan biosynthetic process
AYN53_RS18110	COG0814	amino acid
AYN53_RS18115	COG0513	Belongs to the DEAD box helicase family
AYN53_RS18155	COG0195	Participates in both transcription termination and antitermination
AYN53_RS18180	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AYN53_RS18190	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AYN53_RS18195	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AYN53_RS18205	COG1534	Rna-binding protein
AYN53_RS18210	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AYN53_RS18215	COG2027	D-alanyl-D-alanine carboxypeptidase
AYN53_RS18225	COG0697	spore germination
AYN53_RS18240	COG0142	geranyltranstransferase activity
AYN53_RS18245	COG3423	Transcriptional regulator
AYN53_RS18255	COG5007	Belongs to the BolA IbaG family
AYN53_RS18260	COG3113	response to antibiotic
AYN53_RS18265	COG2854	intermembrane phospholipid transfer
AYN53_RS18270	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AYN53_RS18275	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AYN53_RS18280	COG1127	ABC transporter
AYN53_RS18285	COG0530	calcium, potassium:sodium antiporter activity
AYN53_RS18290	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AYN53_RS18290	COG0517	IMP dehydrogenase activity
AYN53_RS18295	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AYN53_RS18300	COG3117	lipopolysaccharide transmembrane transporter activity
AYN53_RS18305	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AYN53_RS18310	COG1137	ATPase activity
AYN53_RS18315	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AYN53_RS18320	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AYN53_RS18335	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN53_RS18340	COG0515	serine threonine protein kinase
AYN53_RS18350	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AYN53_RS18355	COG0784	Response regulator, receiver
AYN53_RS18355	COG2198	Histidine kinase
AYN53_RS18355	COG5002	protein histidine kinase activity
AYN53_RS18360	COG1242	4 iron, 4 sulfur cluster binding
AYN53_RS18365	COG0067	glutamate synthase
AYN53_RS18365	COG0069	glutamate synthase activity
AYN53_RS18365	COG0070	glutamate synthase
AYN53_RS18370	COG0493	'glutamate synthase
AYN53_RS18375	COG4804	nuclease activity
AYN53_RS18380	COG2731	YhcH YjgK YiaL family protein
AYN53_RS18410	COG2969	positive regulation of protein catabolic process
AYN53_RS18415	COG0625	glutathione transferase activity
AYN53_RS18430	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AYN53_RS18435	COG3105	Protein conserved in bacteria
AYN53_RS18440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AYN53_RS18445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AYN53_RS18465	COG2732	(Barnase) inhibitor
AYN53_RS18485	COG0583	DNA-binding transcription factor activity
AYN53_RS18490	COG0312	modulator of DNA gyrase
AYN53_RS18495	COG3164	Protein of unknown function
AYN53_RS18500	COG1530	ribonuclease E activity
AYN53_RS18510	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AYN53_RS18515	COG1792	Involved in formation and maintenance of cell shape
AYN53_RS18520	COG1077	Cell shape determining protein MreB Mrl
AYN53_RS18530	COG2200	EAL domain
AYN53_RS18530	COG2199	diguanylate cyclase activity
AYN53_RS18535	COG0604	alcohol dehydrogenase
AYN53_RS18545	COG0511	ligase activity, forming carbon-carbon bonds
AYN53_RS18550	COG0439	Biotin carboxylase
AYN53_RS18555	COG3924	membrane
AYN53_RS18560	COG4145	pantothenate transmembrane transporter activity
AYN53_RS18570	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AYN53_RS18580	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AYN53_RS18590	COG1309	transcriptional regulator
AYN53_RS18595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYN53_RS18600	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AYN53_RS18645	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AYN53_RS18665	COG0551	DNA topoisomerase type I activity
AYN53_RS18675	COG0758	DNA mediated transformation
AYN53_RS18695	COG0569	domain protein
AYN53_RS18705	COG3036	rescue of stalled ribosome
AYN53_RS18710	COG0789	Transcriptional regulator
AYN53_RS18750	COG0201	protein transport
AYN53_RS18840	COG0089	rRNA binding
AYN53_RS18915	COG2964	Protein conserved in bacteria
AYN53_RS18920	COG0545	Peptidyl-prolyl cis-trans isomerase
AYN53_RS18930	COG1047	Peptidyl-prolyl cis-trans
AYN53_RS18935	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AYN53_RS18950	COG0488	(ABC) transporter
AYN53_RS18955	COG0429	hydrolase of the alpha beta-hydrolase fold
AYN53_RS18965	COG3954	Phosphoribulokinase
AYN53_RS18970	COG1765	OsmC-like protein
AYN53_RS18975	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AYN53_RS18980	COG1289	transmembrane transporter activity
AYN53_RS18985	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AYN53_RS18990	COG0512	Glutamine amidotransferase of anthranilate synthase
AYN53_RS18995	COG2184	nucleotidyltransferase activity
AYN53_RS19005	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AYN53_RS19015	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AYN53_RS19020	COG2146	nitrite reductase [NAD(P)H] activity
AYN53_RS19025	COG2116	formate transmembrane transporter activity
AYN53_RS19040	COG0626	cystathionine gamma-synthase activity
AYN53_RS19055	COG1735	metal-dependent hydrolase with the TIM-barrel fold
AYN53_RS19060	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AYN53_RS19065	COG3457	Alanine racemase
AYN53_RS19075	COG2188	Transcriptional regulator
AYN53_RS19080	COG0180	Tryptophanyl-tRNA synthetase
AYN53_RS19090	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AYN53_RS19095	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AYN53_RS19100	COG3266	domain, Protein
AYN53_RS19115	COG4796	Type ii and iii secretion system protein
AYN53_RS19130	COG3166	PFAM Fimbrial assembly family protein
AYN53_RS19135	COG4972	Pilus assembly protein
AYN53_RS19140	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AYN53_RS19145	COG0494	nUDIX hydrolase
AYN53_RS19155	COG1011	Hydrolase
AYN53_RS19160	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AYN53_RS19195	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AYN53_RS19200	COG2183	response to ionizing radiation
AYN53_RS19205	COG1918	ferrous iron import across plasma membrane
AYN53_RS19210	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AYN53_RS19240	COG2610	gluconate transmembrane transporter activity
AYN53_RS19245	COG1640	4-alpha-glucanotransferase
AYN53_RS19250	COG0058	SHG alpha-glucan phosphorylase activity
AYN53_RS19270	COG1349	DNA-binding transcription factor activity
AYN53_RS19285	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AYN53_RS19325	COG0058	SHG alpha-glucan phosphorylase activity
AYN53_RS19350	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AYN53_RS19355	COG2095	MarC family integral membrane protein
AYN53_RS19360	COG2610	gluconate transmembrane transporter activity
AYN53_RS19365	COG3265	gluconokinase activity
AYN53_RS19370	COG1609	Transcriptional regulator
AYN53_RS19375	COG1741	Belongs to the pirin family
AYN53_RS19380	COG0673	inositol 2-dehydrogenase activity
AYN53_RS19390	COG1247	-acetyltransferase
AYN53_RS19395	COG0405	Gamma-glutamyltransferase
AYN53_RS19405	COG0584	glycerophosphoryl diester phosphodiesterase
AYN53_RS19435	COG0410	ABC transporter
AYN53_RS19445	COG4177	L-phenylalanine transmembrane transporter activity
AYN53_RS19450	COG0559	Belongs to the binding-protein-dependent transport system permease family
AYN53_RS19455	COG0683	leucine binding
AYN53_RS19460	COG0456	acetyltransferase
AYN53_RS19475	COG0683	leucine binding
AYN53_RS19480	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AYN53_RS19485	COG2177	Part of the ABC transporter FtsEX involved in
AYN53_RS19490	COG2884	Cell division ATP-binding protein ftsE
AYN53_RS19495	COG0552	protein localization to endoplasmic reticulum
AYN53_RS19500	COG0742	ribosomal rna small subunit methyltransferase
AYN53_RS19505	COG3776	membrane
AYN53_RS19515	COG3714	YhhN family
AYN53_RS19535	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AYN53_RS19545	COG0477	Major facilitator Superfamily
AYN53_RS19550	COG0628	permease
AYN53_RS19555	COG2091	lysine biosynthetic process via aminoadipic acid
AYN53_RS19560	COG0747	negative chemotaxis
AYN53_RS19565	COG0601	transmembrane transport
AYN53_RS19570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AYN53_RS19590	COG2188	Transcriptional regulator
AYN53_RS19600	COG3414	Phosphotransferase system galactitol-specific IIB component
AYN53_RS19605	COG3775	system Galactitol-specific IIC component
AYN53_RS19620	COG0191	fructose-bisphosphate aldolase activity
AYN53_RS19625	COG0842	Transport permease protein
AYN53_RS19630	COG0842	Transport permease protein
AYN53_RS19630	COG1129	ABC transporter
AYN53_RS19635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYN53_RS19650	COG4571	Outer membrane protease
AYN53_RS19660	COG2200	EAL domain
AYN53_RS19700	COG2081	HI0933 family
AYN53_RS19705	COG0306	phosphate transporter
AYN53_RS19715	COG0589	response to stress
AYN53_RS19725	COG3104	oligopeptide transport
AYN53_RS19735	COG0339	signal peptide processing
AYN53_RS19740	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AYN53_RS19745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AYN53_RS19760	COG3549	Plasmid maintenance system killer
AYN53_RS19765	COG3093	addiction module antidote protein HigA
AYN53_RS19770	COG3065	identical protein binding
AYN53_RS19775	COG2197	response regulator
AYN53_RS19780	COG3720	iron ion transport
AYN53_RS19785	COG4771	TonB-dependent receptor
AYN53_RS19790	COG4558	Periplasmic binding protein
AYN53_RS19800	COG3721	Heme iron utilization protein
AYN53_RS19810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AYN53_RS19830	COG3247	response to pH
AYN53_RS19835	COG2771	luxR family
AYN53_RS19850	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AYN53_RS19855	COG2207	Transcriptional regulator
AYN53_RS19860	COG2207	Transcriptional regulator
AYN53_RS19865	COG0076	glutamate decarboxylase activity
AYN53_RS19870	COG1858	cytochrome C peroxidase
AYN53_RS19880	COG2197	response regulator
AYN53_RS19885	COG0583	DNA-binding transcription factor activity
AYN53_RS19890	COG1295	ribonuclease BN
AYN53_RS19895	COG0477	Major facilitator Superfamily
AYN53_RS19905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AYN53_RS19910	COG0612	Peptidase, M16
AYN53_RS19920	COG2199	diguanylate cyclase activity
AYN53_RS19920	COG2200	EAL domain
AYN53_RS19925	COG3118	belongs to the thioredoxin family
AYN53_RS19925	COG0457	Tetratricopeptide repeat
AYN53_RS19930	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AYN53_RS19935	COG1215	transferase activity, transferring glycosyl groups
AYN53_RS19940	COG1215	transferase activity, transferring glycosyl groups
AYN53_RS19965	COG2194	sulfuric ester hydrolase activity
AYN53_RS19975	COG0814	amino acid
AYN53_RS19980	COG4608	Belongs to the ABC transporter superfamily
AYN53_RS19985	COG0444	Belongs to the ABC transporter superfamily
AYN53_RS19990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AYN53_RS19995	COG0601	transmembrane transport
AYN53_RS20005	COG0747	negative chemotaxis
AYN53_RS20020	COG2194	sulfuric ester hydrolase activity
AYN53_RS20025	COG2223	nitrite transmembrane transporter activity
AYN53_RS20030	COG5571	outer membrane autotransporter
AYN53_RS20035	COG2818	Glycosylase
AYN53_RS20040	COG0456	acetyltransferase
AYN53_RS20045	COG0243	molybdopterin cofactor binding
AYN53_RS20050	COG2885	chlorophyll binding
AYN53_RS20065	COG2944	sequence-specific DNA binding
AYN53_RS20070	COG1278	Cold shock
AYN53_RS20095	COG3274	enterobacterial common antigen metabolic process
AYN53_RS20100	COG4682	membrane
AYN53_RS20105	COG2992	FlgJ-related protein
AYN53_RS20120	COG3977	Valine--pyruvate aminotransferase
AYN53_RS20125	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AYN53_RS20130	COG1414	Transcriptional regulator
AYN53_RS20140	COG2731	YhcH YjgK YiaL family protein
AYN53_RS20145	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AYN53_RS20150	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AYN53_RS20155	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AYN53_RS20160	COG1070	Carbohydrate kinase
AYN53_RS20165	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AYN53_RS20170	COG3623	hexulose-6-phosphate isomerase
AYN53_RS20175	COG0235	Class ii aldolase
AYN53_RS20180	COG1012	belongs to the aldehyde dehydrogenase family
AYN53_RS20195	COG3276	selenocysteine insertion sequence binding
AYN53_RS20205	COG0625	glutathione transferase activity
AYN53_RS20210	COG2258	MOSC domain
AYN53_RS20215	COG1566	PFAM secretion protein HlyD family protein
AYN53_RS20225	COG2213	PTS system mannitol-specific
AYN53_RS20225	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN53_RS20235	COG3722	fumarate hydratase activity
AYN53_RS20255	COG1620	l-lactate permease
AYN53_RS20260	COG2186	Transcriptional regulator
AYN53_RS20270	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AYN53_RS20275	COG1045	serine acetyltransferase
AYN53_RS20290	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AYN53_RS20295	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AYN53_RS20310	COG4942	peptidase
AYN53_RS20315	COG2861	carbohydrate metabolic process
AYN53_RS20320	COG1216	Glycosyl transferase, family 2
AYN53_RS20330	COG0156	8-amino-7-oxononanoate synthase activity
AYN53_RS20340	COG0859	PFAM glycosyl transferase family 9
AYN53_RS20345	COG0859	PFAM glycosyl transferase family 9
AYN53_RS20365	COG3642	lipopolysaccharide core region biosynthetic process
AYN53_RS20370	COG1442	glycosyl transferase family 8
AYN53_RS20375	COG1442	glycosyl transferase family 8
AYN53_RS20380	COG0438	transferase activity, transferring glycosyl groups
AYN53_RS20385	COG0859	PFAM glycosyl transferase family 9
AYN53_RS20390	COG0515	serine threonine protein kinase
AYN53_RS20395	COG0438	transferase activity, transferring glycosyl groups
AYN53_RS20400	COG0859	PFAM glycosyl transferase family 9
AYN53_RS20405	COG1519	Transferase
AYN53_RS20435	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AYN53_RS20460	COG1561	YicC-like family, N-terminal region
AYN53_RS20580	COG3710	Transcriptional regulator
AYN53_RS20585	COG0531	amino acid
AYN53_RS20590	COG1982	Orn Lys Arg decarboxylase major
AYN53_RS20595	COG3104	oligopeptide transport
AYN53_RS20600	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AYN53_RS20605	COG2860	membrane
AYN53_RS20615	COG0194	GDP metabolic process
AYN53_RS20625	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AYN53_RS20630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AYN53_RS20635	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AYN53_RS20640	COG0786	glutamate:sodium symporter activity
AYN53_RS20645	COG2233	PERMEase
AYN53_RS20650	COG2982	Protein involved in outer membrane biogenesis
AYN53_RS20660	COG0582	viral genome integration into host DNA
AYN53_RS20745	COG2814	Major facilitator Superfamily
AYN53_RS20755	COG0697	spore germination
AYN53_RS20765	COG0457	Tetratricopeptide repeat
AYN53_RS20795	COG1388	LysM domain
AYN53_RS20795	COG1470	cell adhesion involved in biofilm formation
AYN53_RS20805	COG2252	PERMEase
AYN53_RS20815	COG2271	Major facilitator Superfamily
AYN53_RS20825	COG3851	Histidine kinase
AYN53_RS20830	COG2197	response regulator
AYN53_RS20835	COG0440	acetolactate synthase activity
AYN53_RS20840	COG0028	Belongs to the TPP enzyme family
AYN53_RS20850	COG2814	Major facilitator Superfamily
AYN53_RS20855	COG0641	radical SAM
AYN53_RS20865	COG2149	membrane
AYN53_RS20875	COG3119	arylsulfatase activity
AYN53_RS20885	COG2207	Transcriptional regulator
AYN53_RS20900	COG2188	Transcriptional regulator
AYN53_RS20920	COG5645	(Lipo)protein
AYN53_RS20925	COG0823	Involved in the tonB-independent uptake of proteins
AYN53_RS20940	COG0561	phosphatase activity
AYN53_RS20945	COG3753	Protein conserved in bacteria
AYN53_RS20950	COG0187	DNA topoisomerase II activity
AYN53_RS20960	COG0592	DNA-directed DNA polymerase activity
AYN53_RS21010	COG0814	amino acid
AYN53_RS21025	COG2091	lysine biosynthetic process via aminoadipic acid
AYN53_RS21040	COG0431	NADPH-dependent FMN reductase
AYN53_RS21045	COG2204	response regulator
AYN53_RS21060	COG1053	succinate dehydrogenase
AYN53_RS21060	COG3976	FMN-binding domain protein
AYN53_RS21075	COG2252	PERMEase
AYN53_RS21080	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AYN53_RS21115	COG0704	Plays a role in the regulation of phosphate uptake
AYN53_RS21120	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AYN53_RS21125	COG0581	inorganic phosphate transmembrane transporter activity
AYN53_RS21130	COG0573	inorganic phosphate transmembrane transporter activity
AYN53_RS21135	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AYN53_RS21180	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AYN53_RS21195	COG3312	ion transport
AYN53_RS21215	COG0716	FMN binding
AYN53_RS21220	COG1522	sequence-specific DNA binding
AYN53_RS21250	COG1129	ABC transporter
AYN53_RS21255	COG1172	Belongs to the binding-protein-dependent transport system permease family
AYN53_RS21260	COG1879	ABC-type sugar transport system periplasmic component
AYN53_RS21265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AYN53_RS21270	COG1609	Transcriptional regulator
AYN53_RS21275	COG0477	Major facilitator Superfamily
AYN53_RS21280	COG2186	Transcriptional regulator
AYN53_RS21320	COG3085	chromosome segregation
AYN53_RS21325	COG0606	chelatase, subunit chli
AYN53_RS21345	COG3978	acetolactate synthase activity
AYN53_RS21350	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AYN53_RS21360	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AYN53_RS21375	COG0583	DNA-binding transcription factor activity
AYN53_RS21385	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AYN53_RS21390	COG0210	DNA helicase
AYN53_RS21405	COG3118	belongs to the thioredoxin family
AYN53_RS21415	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AYN53_RS21420	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AYN53_RS21425	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
AYN53_RS21430	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AYN53_RS21435	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AYN53_RS21440	COG1088	dTDP-glucose 4,6-dehydratase activity
AYN53_RS21445	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AYN53_RS21450	COG0456	acetyltransferase
AYN53_RS21455	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AYN53_RS21460	COG2244	polysaccharide biosynthetic process
AYN53_RS21480	COG1113	amino acid transport
AYN53_RS21505	COG0641	radical SAM
AYN53_RS21510	COG3119	arylsulfatase activity
AYN53_RS21515	COG3071	HemY protein
AYN53_RS21520	COG2959	enzyme of heme biosynthesis
AYN53_RS21525	COG1587	Uroporphyrinogen-III synthase
AYN53_RS21535	COG3072	Adenylate cyclase
AYN53_RS21550	COG5567	small periplasmic lipoprotein
AYN53_RS21560	COG3159	Protein conserved in bacteria
AYN53_RS21570	COG1011	Hydrolase
AYN53_RS21575	COG0210	DNA helicase
AYN53_RS21580	COG3698	Phosphodiester glycosidase
AYN53_RS21585	COG0598	Magnesium transport protein CorA
AYN53_RS21600	COG2962	Rard protein
AYN53_RS21605	COG2050	protein possibly involved in aromatic compounds catabolism
AYN53_RS21610	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
AYN53_RS21615	COG0514	ATP-dependent DNA helicase (RecQ)
AYN53_RS21620	COG1280	lysine exporter protein (LysE YggA)
AYN53_RS21630	COG2267	carboxylic ester hydrolase activity
AYN53_RS21635	COG0561	phosphatase activity
AYN53_RS21640	COG0697	spore germination
AYN53_RS21645	COG0583	DNA-binding transcription factor activity
AYN53_RS21655	COG0412	Dienelactone hydrolase
AYN53_RS21660	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
AYN53_RS21680	COG0800	Aldolase
AYN53_RS21685	COG3734	2-keto-3-deoxy-galactonokinase
AYN53_RS21690	COG1414	Transcriptional regulator
AYN53_RS21695	COG1322	Protein conserved in bacteria
AYN53_RS21705	COG3165	ubiquinone biosynthetic process from chorismate
AYN53_RS21715	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AYN53_RS21725	COG0805	protein transport
AYN53_RS21745	COG0543	2 iron, 2 sulfur cluster binding
AYN53_RS21765	COG1739	Uncharacterized protein family UPF0029
AYN53_RS21770	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AYN53_RS21775	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
AYN53_RS21800	COG1763	Mo-molybdopterin cofactor biosynthetic process
AYN53_RS21805	COG0746	molybdenum cofactor guanylyltransferase activity
AYN53_RS21810	COG3084	Protein conserved in bacteria
AYN53_RS21815	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AYN53_RS21820	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AYN53_RS21825	COG5339	Protein conserved in bacteria
AYN53_RS21830	COG0204	Acyl-transferase
AYN53_RS21840	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AYN53_RS21840	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AYN53_RS21855	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AYN53_RS21865	COG2204	response regulator
AYN53_RS21870	COG3852	Histidine kinase
AYN53_RS21875	COG0174	glutamine synthetase
AYN53_RS21880	COG1217	gtp-binding protein TYPA
AYN53_RS21885	COG2188	Transcriptional regulator
AYN53_RS21890	COG1082	Xylose isomerase domain protein TIM barrel
AYN53_RS21895	COG2271	Major facilitator Superfamily
AYN53_RS21900	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AYN53_RS21905	COG2211	Major facilitator Superfamily
AYN53_RS21910	COG2211	Major facilitator Superfamily
AYN53_RS21915	COG1501	Belongs to the glycosyl hydrolase 31 family
AYN53_RS21920	COG2017	converts alpha-aldose to the beta-anomer
AYN53_RS21925	COG2942	2-epimerase
AYN53_RS21930	COG3684	Belongs to the aldolase LacD family
AYN53_RS21935	COG2084	Dehydrogenase
AYN53_RS21940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AYN53_RS21945	COG1349	DNA-binding transcription factor activity
AYN53_RS21950	COG1011	Hydrolase
AYN53_RS21965	COG0456	acetyltransferase
AYN53_RS21990	COG2864	formate dehydrogenase
AYN53_RS21995	COG0437	4 iron, 4 sulfur cluster binding
AYN53_RS22020	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AYN53_RS22025	COG2258	MOSC domain
AYN53_RS22030	COG2205	protein histidine kinase activity
AYN53_RS22035	COG0745	RESPONSE REGULATOR receiver
AYN53_RS22040	COG3678	ATP-independent chaperone mediated protein folding
AYN53_RS22055	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AYN53_RS22075	COG3152	Membrane
AYN53_RS22080	COG3691	Protein conserved in bacteria
AYN53_RS22085	COG0589	response to stress
AYN53_RS22095	COG1494	fructose-1,6-bisphosphatase
AYN53_RS22105	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AYN53_RS22130	COG1575	Belongs to the MenA family. Type 1 subfamily
AYN53_RS22145	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AYN53_RS22150	COG1609	Transcriptional regulator
AYN53_RS22155	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AYN53_RS22165	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
AYN53_RS22175	COG0626	cystathionine gamma-synthase activity
AYN53_RS22180	COG0460	homoserine dehydrogenase
AYN53_RS22180	COG0527	aspartate kinase activity
AYN53_RS22190	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AYN53_RS22200	COG0697	spore germination
AYN53_RS22205	COG3738	Protein conserved in bacteria
AYN53_RS22210	COG0371	Dehydrogenase
AYN53_RS22215	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AYN53_RS22225	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AYN53_RS22230	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AYN53_RS22235	COG1882	Formate acetyltransferase
AYN53_RS22245	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AYN53_RS22250	COG2207	Transcriptional regulator
AYN53_RS22255	COG2194	sulfuric ester hydrolase activity
AYN53_RS22270	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AYN53_RS22285	COG0583	DNA-binding transcription factor activity
AYN53_RS22295	COG1473	amidohydrolase
AYN53_RS22300	COG0477	Major facilitator Superfamily
AYN53_RS22305	COG1309	transcriptional regulator
AYN53_RS22320	COG4206	TonB-dependent receptor
AYN53_RS22355	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AYN53_RS22360	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AYN53_RS22360	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AYN53_RS22395	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AYN53_RS22400	COG0250	Participates in transcription elongation, termination and antitermination
AYN53_RS22435	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AYN53_RS22445	COG2104	thiamine diphosphate biosynthetic process
AYN53_RS22450	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AYN53_RS22485	COG3068	Protein conserved in bacteria
AYN53_RS22500	COG3678	ATP-independent chaperone mediated protein folding
AYN53_RS22505	COG4191	Histidine kinase
AYN53_RS22510	COG2204	response regulator
AYN53_RS22515	COG0151	Belongs to the GarS family
AYN53_RS22545	COG0456	acetyltransferase
AYN53_RS22555	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AYN53_RS22560	COG2224	Isocitrate lyase
AYN53_RS22570	COG1414	Transcriptional regulator
AYN53_RS22575	COG0646	methionine synthase
AYN53_RS22575	COG1410	methionine synthase
AYN53_RS22580	COG1283	sodium-dependent phosphate transmembrane transporter activity
AYN53_RS22590	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AYN53_RS22630	COG1187	pseudouridine synthase activity
AYN53_RS22640	COG0527	aspartate kinase activity
AYN53_RS22665	COG3833	ABC-type maltose transport systems, permease component
AYN53_RS22670	COG1175	transmembrane transport
AYN53_RS22675	COG2182	Extracellular solute-binding protein
AYN53_RS22680	COG3842	ATPase activity
AYN53_RS22710	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AYN53_RS22720	COG0534	Mate efflux family protein
AYN53_RS22725	COG3237	CsbD-like
AYN53_RS22730	COG0735	belongs to the Fur family
AYN53_RS22735	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AYN53_RS22745	COG0604	alcohol dehydrogenase
AYN53_RS22750	COG0305	Participates in initiation and elongation during chromosome replication
AYN53_RS22760	COG1448	Aminotransferase
AYN53_RS22765	COG0567	Dehydrogenase, E1 component
AYN53_RS22775	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AYN53_RS22780	COG0045	succinate-CoA ligase (ADP-forming) activity
AYN53_RS22785	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AYN53_RS22790	COG0471	metal ion transport
AYN53_RS22795	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AYN53_RS22810	COG3700	Belongs to the class B bacterial acid phosphatase family
AYN53_RS22815	COG0432	Pfam Uncharacterised protein family UPF0047
AYN53_RS22820	COG2315	Protein conserved in bacteria
AYN53_RS22825	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AYN53_RS22830	COG0629	single-stranded DNA binding
AYN53_RS22840	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AYN53_RS22845	COG2207	Transcriptional regulator
AYN53_RS22850	COG0789	Transcriptional regulator
AYN53_RS22855	COG2252	PERMEase
AYN53_RS22860	COG0025	NhaP-type Na H and K H
AYN53_RS22870	COG3162	membrane
AYN53_RS22875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AYN53_RS22890	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
AYN53_RS22895	COG0437	4 iron, 4 sulfur cluster binding
AYN53_RS22900	COG3301	Polysulphide reductase, NrfD
AYN53_RS22905	COG1138	Cytochrome C-type biogenesis protein
AYN53_RS22910	COG3088	subunit of a heme lyase
AYN53_RS22915	COG4235	cytochrome complex assembly
AYN53_RS22920	COG1301	dicarboxylic acid transport
AYN53_RS22930	COG4608	Belongs to the ABC transporter superfamily
AYN53_RS22935	COG0444	Belongs to the ABC transporter superfamily
AYN53_RS22940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AYN53_RS22945	COG0601	transmembrane transport
AYN53_RS22965	COG1289	transmembrane transporter activity
AYN53_RS22970	COG1566	PFAM secretion protein HlyD family protein
AYN53_RS22990	COG1028	Short-chain dehydrogenase reductase Sdr
AYN53_RS22995	COG1024	Enoyl-CoA hydratase
AYN53_RS23000	COG0477	Major facilitator Superfamily
AYN53_RS23005	COG4670	ketone body catabolic process
AYN53_RS23025	COG1028	Short-chain dehydrogenase reductase Sdr
AYN53_RS23050	COG2764	glyoxalase bleomycin resistance protein dioxygenase
AYN53_RS23055	COG2824	Alkylphosphonate utilization operon protein PhnA
AYN53_RS23075	COG0642	Histidine kinase
AYN53_RS23080	COG0745	RESPONSE REGULATOR receiver
AYN53_RS23085	COG2194	sulfuric ester hydrolase activity
AYN53_RS23090	COG0531	amino acid
AYN53_RS23095	COG2207	Transcriptional regulator
AYN53_RS23100	COG1982	Orn Lys Arg decarboxylase major
AYN53_RS23105	COG3647	Membrane
AYN53_RS23110	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AYN53_RS23110	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AYN53_RS23115	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AYN53_RS23125	COG4565	transcriptional regulatory protein
AYN53_RS23130	COG3290	protein histidine kinase activity
AYN53_RS23135	COG3592	Divergent 4Fe-4S mono-cluster
AYN53_RS23140	COG2388	GCN5-related N-acetyl-transferase
AYN53_RS23395	COG1309	transcriptional regulator
AYN53_RS23400	COG4232	protein-disulfide reductase activity
AYN53_RS23410	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AYN53_RS23415	COG1027	Aspartate ammonia-lyase
AYN53_RS23420	COG3030	protein affecting phage T7 exclusion by the F plasmid
AYN53_RS23450	COG1509	lysine 2,3-aminomutase activity
AYN53_RS23460	COG5510	response to toxic substance
AYN53_RS23470	COG2076	Multidrug Resistance protein
AYN53_RS23475	COG3040	lipid binding
AYN53_RS23480	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AYN53_RS23495	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AYN53_RS23500	COG1053	succinate dehydrogenase
AYN53_RS23510	COG0531	amino acid
AYN53_RS23525	COG3264	Mechanosensitive ion channel
AYN53_RS23525	COG1511	domain protein
AYN53_RS23560	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AYN53_RS23565	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AYN53_RS23565	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AYN53_RS23570	COG0802	atpase or kinase
AYN53_RS23575	COG0860	N-Acetylmuramoyl-L-alanine amidase
AYN53_RS23580	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AYN53_RS23595	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AYN53_RS23600	COG0330	HflC and HflK could
AYN53_RS23605	COG0330	HflC and HflK could
AYN53_RS23610	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AYN53_RS23625	COG0557	exoribonuclease II activity
AYN53_RS23630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AYN53_RS23635	COG0754	glutathionylspermidine amidase activity
AYN53_RS23640	COG1960	acyl-CoA dehydrogenase activity
AYN53_RS23650	COG3650	response to hydrogen peroxide
AYN53_RS23655	COG1073	alpha beta
AYN53_RS23670	COG3037	sugar-specific permease SgaT UlaA
AYN53_RS23675	COG3414	Phosphotransferase system galactitol-specific IIB component
AYN53_RS23680	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN53_RS23700	COG3477	response to acidic pH
AYN53_RS23720	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AYN53_RS23730	COG2271	Major facilitator Superfamily
AYN53_RS23735	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AYN53_RS23740	COG4670	ketone body catabolic process
AYN53_RS23745	COG1024	Enoyl-CoA hydratase
AYN53_RS23760	COG1309	transcriptional regulator
AYN53_RS23765	COG3061	Opacity-associated protein A
AYN53_RS23770	COG0545	Peptidyl-prolyl cis-trans isomerase
AYN53_RS23775	COG1113	amino acid transport
AYN53_RS23795	COG0697	spore germination
AYN53_RS23800	COG1733	regulation of RNA biosynthetic process
AYN53_RS23805	COG0737	Belongs to the 5'-nucleotidase family
AYN53_RS23810	COG1218	3'(2'),5'-bisphosphate nucleotidase
AYN53_RS23820	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AYN53_RS23830	COG1253	flavin adenine dinucleotide binding
AYN53_RS23840	COG0729	surface antigen
AYN53_RS23845	COG2911	Protein conserved in bacteria
AYN53_RS23850	COG2105	PFAM AIG2 family protein
AYN53_RS23855	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AYN53_RS23860	COG1879	ABC-type sugar transport system periplasmic component
AYN53_RS23865	COG1129	ABC transporter
AYN53_RS23870	COG1172	Belongs to the binding-protein-dependent transport system permease family
AYN53_RS23875	COG1172	Belongs to the binding-protein-dependent transport system permease family
AYN53_RS23890	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AYN53_RS23900	COG0312	modulator of DNA gyrase
AYN53_RS23905	COG3783	Cytochrome b(562)
AYN53_RS23915	COG2026	Addiction module toxin, RelE StbE family
AYN53_RS23920	COG0602	queuosine metabolic process
AYN53_RS23925	COG1328	CTP reductase activity
AYN53_RS23940	COG1609	Transcriptional regulator
AYN53_RS23950	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AYN53_RS23960	COG0251	oxidation-reduction process
AYN53_RS23980	COG2731	YhcH YjgK YiaL family protein
AYN53_RS24000	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
AYN53_RS24005	COG0456	acetyltransferase
AYN53_RS24015	COG0525	valine-tRNA ligase activity
AYN53_RS24020	COG2927	DNA polymerase III (CHI subunit)
AYN53_RS24030	COG0795	lipopolysaccharide-transporting ATPase activity
AYN53_RS24035	COG0795	lipopolysaccharide-transporting ATPase activity
AYN53_RS24040	COG0433	COG0433 Predicted ATPase
AYN53_RS24045	COG1064	alcohol dehydrogenase
AYN53_RS24110	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
AYN53_RS24120	COG0582	viral genome integration into host DNA
AYN53_RS24125	COG4974	Belongs to the 'phage' integrase family
AYN53_RS24135	COG3539	Fimbrial protein
AYN53_RS24140	COG3121	Chaperone
AYN53_RS24200	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AYN53_RS24235	COG0305	Participates in initiation and elongation during chromosome replication
AYN53_RS24480	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AYN53_RS24555	COG0371	Dehydrogenase
AYN53_RS24590	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AYN53_RS24595	COG5301	cellulose 1,4-beta-cellobiosidase activity
AYN53_RS24610	COG5301	cellulose 1,4-beta-cellobiosidase activity
AYN53_RS24635	COG0741	lytic transglycosylase activity
AYN53_RS24740	COG3969	phosphoadenosine phosphosulfate
AYN53_RS24745	COG1475	DNA binding
AYN53_RS25035	COG1475	DNA binding
AYN53_RS25270	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AYN53_RS25300	COG1294	oxidase, subunit
AYN53_RS25305	COG1271	oxidase subunit
AYN53_RS25320	COG3220	belongs to the UPF0276 family
AYN53_RS25350	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AYN53_RS25370	COG3829	transcription factor binding
AYN53_RS25370	COG3290	protein histidine kinase activity
AYN53_RS25385	COG2721	sulfolactate sulfo-lyase activity
AYN53_RS25405	COG0726	polysaccharide deacetylase
AYN53_RS25410	COG0297	glycogen (starch) synthase activity
AYN53_RS25415	COG1560	Kdo2-lipid A biosynthetic process
AYN53_RS25420	COG2990	Protein conserved in bacteria
AYN53_RS25430	COG1116	anion transmembrane transporter activity
AYN53_RS25690	COG3121	Chaperone
AYN53_RS25700	COG3188	usher protein
AYN53_RS25705	COG3121	Chaperone
AYN53_RS25715	COG1278	Cold shock
AYN53_RS25730	COG1252	NADH dehydrogenase
AYN53_RS25790	COG2200	EAL domain
AYN53_RS25790	COG2771	luxR family