locus-tag	class	description
EAKF1_RS00040	COG3119	arylsulfatase activity
EAKF1_RS00045	COG0641	radical SAM
EAKF1_RS00050	COG0076	glutamate decarboxylase activity
EAKF1_RS00055	COG0531	amino acid
EAKF1_RS00065	COG1649	PFAM Uncharacterised BCR, COG1649
EAKF1_RS00075	COG3436	PFAM IS66 Orf2 family protein
EAKF1_RS00085	COG4372	Transposase
EAKF1_RS00095	COG2200	EAL domain
EAKF1_RS00095	COG2202	Pas domain
EAKF1_RS00095	COG2199	diguanylate cyclase activity
EAKF1_RS00100	COG1764	response to oxidative stress
EAKF1_RS00115	COG1064	alcohol dehydrogenase
EAKF1_RS00125	COG3093	addiction module antidote protein HigA
EAKF1_RS00130	COG2864	formate dehydrogenase
EAKF1_RS00135	COG0437	4 iron, 4 sulfur cluster binding
EAKF1_RS00140	COG3383	formate dehydrogenase (NAD+) activity
EAKF1_RS00140	COG0243	molybdopterin cofactor binding
EAKF1_RS00145	COG0243	molybdopterin cofactor binding
EAKF1_RS00145	COG3383	formate dehydrogenase (NAD+) activity
EAKF1_RS00150	COG0697	spore germination
EAKF1_RS00160	COG2223	nitrite transmembrane transporter activity
EAKF1_RS00170	COG1140	nitrate reductase beta subunit
EAKF1_RS00175	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EAKF1_RS00180	COG2181	nitrate reductase activity
EAKF1_RS00185	COG0384	phenazine biosynthesis protein PhzF
EAKF1_RS00190	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EAKF1_RS00195	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EAKF1_RS00210	COG1113	amino acid transport
EAKF1_RS00220	COG4772	TonB-dependent receptor
EAKF1_RS00225	COG2130	NADP-dependent
EAKF1_RS00230	COG1247	-acetyltransferase
EAKF1_RS00235	COG3238	Protein conserved in bacteria
EAKF1_RS00255	COG1470	cell adhesion involved in biofilm formation
EAKF1_RS00255	COG1388	LysM domain
EAKF1_RS00265	COG1177	transmembrane transport
EAKF1_RS00270	COG1176	ABC-type spermidine putrescine transport system, permease component I
EAKF1_RS00275	COG3842	ATPase activity
EAKF1_RS00280	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EAKF1_RS00285	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EAKF1_RS00295	COG0826	peptidase U32
EAKF1_RS00305	COG0500	methyltransferase
EAKF1_RS00310	COG1275	C4-dicarboxylate transporter malic acid transport protein
EAKF1_RS00315	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EAKF1_RS00320	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EAKF1_RS00325	COG2841	Protein conserved in bacteria
EAKF1_RS00340	COG5383	Protein conserved in bacteria
EAKF1_RS00345	COG0583	DNA-binding transcription factor activity
EAKF1_RS00350	COG3038	cytochrome b561
EAKF1_RS00355	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EAKF1_RS00360	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EAKF1_RS00385	COG1643	Atp-dependent helicase
EAKF1_RS00400	COG0667	Aldo Keto reductase
EAKF1_RS00405	COG3784	Protein of unknown function (DUF1318)
EAKF1_RS00415	COG2911	Protein conserved in bacteria
EAKF1_RS00420	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EAKF1_RS00425	COG3187	Heat shock protein
EAKF1_RS00430	COG3042	response to heat
EAKF1_RS00435	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EAKF1_RS00435	COG0674	pyruvate-flavodoxin oxidoreductase activity
EAKF1_RS00435	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EAKF1_RS00435	COG1013	pyruvate-flavodoxin oxidoreductase activity
EAKF1_RS00450	COG0582	viral genome integration into host DNA
EAKF1_RS00460	COG0513	Belongs to the DEAD box helicase family
EAKF1_RS00480	COG2840	Smr protein MutS2
EAKF1_RS00495	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EAKF1_RS00500	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EAKF1_RS00505	COG0589	response to stress
EAKF1_RS00510	COG3182	Iron-regulated membrane protein
EAKF1_RS00515	COG0668	transmembrane transport
EAKF1_RS00520	COG4166	transmembrane transport
EAKF1_RS00525	COG2866	Carboxypeptidase
EAKF1_RS00530	COG4948	Mandelate Racemase Muconate Lactonizing
EAKF1_RS00535	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EAKF1_RS00540	COG3283	Transcriptional regulator of aromatic amino acids metabolism
EAKF1_RS00550	COG3106	COG3106 Predicted ATPase
EAKF1_RS00555	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EAKF1_RS00565	COG1983	PspC domain protein
EAKF1_RS00575	COG1842	Phage shock protein A
EAKF1_RS00580	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EAKF1_RS00585	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EAKF1_RS00590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EAKF1_RS00595	COG1012	belongs to the aldehyde dehydrogenase family
EAKF1_RS00600	COG1396	sequence-specific DNA binding
EAKF1_RS00600	COG1917	Cupin 2, conserved barrel domain protein
EAKF1_RS00605	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EAKF1_RS00610	COG0174	glutamine synthetase
EAKF1_RS00615	COG0531	amino acid
EAKF1_RS00630	COG4166	transmembrane transport
EAKF1_RS00635	COG4168	peptide transport system, permease
EAKF1_RS00640	COG0583	DNA-binding transcription factor activity
EAKF1_RS00645	COG1073	alpha beta
EAKF1_RS00650	COG1902	pentaerythritol trinitrate reductase activity
EAKF1_RS00655	COG2207	Transcriptional regulator
EAKF1_RS00660	COG1881	PFAM PEBP family protein
EAKF1_RS00665	COG2076	Multidrug Resistance protein
EAKF1_RS00675	COG4171	peptide transport system, permease
EAKF1_RS00680	COG4172	Belongs to the ABC transporter superfamily
EAKF1_RS00690	COG2814	Major facilitator Superfamily
EAKF1_RS00700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EAKF1_RS00715	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EAKF1_RS00720	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EAKF1_RS00720	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EAKF1_RS00730	COG5001	Diguanylate cyclase
EAKF1_RS00755	COG1349	DNA-binding transcription factor activity
EAKF1_RS00765	COG0023	Translation Initiation Factor
EAKF1_RS00775	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EAKF1_RS00780	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
EAKF1_RS00785	COG0671	phosphoesterase, PA-phosphatase related
EAKF1_RS00795	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EAKF1_RS00800	COG0583	DNA-binding transcription factor activity
EAKF1_RS00805	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EAKF1_RS00820	COG0616	signal peptide processing
EAKF1_RS00830	COG1028	Short-chain dehydrogenase reductase Sdr
EAKF1_RS00835	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
EAKF1_RS00850	COG1187	pseudouridine synthase activity
EAKF1_RS00855	COG0009	L-threonylcarbamoyladenylate synthase
EAKF1_RS00860	COG0613	PHP domain protein
EAKF1_RS00865	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EAKF1_RS00870	COG0512	Glutamine amidotransferase of anthranilate synthase
EAKF1_RS00870	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EAKF1_RS00875	COG0135	phosphoribosylanthranilate isomerase activity
EAKF1_RS00875	COG0134	indole-3-glycerol-phosphate synthase activity
EAKF1_RS00890	COG3047	cAMP biosynthetic process
EAKF1_RS00895	COG0727	PFAM Uncharacterised protein family (UPF0153)
EAKF1_RS00910	COG1607	acyl-coa hydrolase
EAKF1_RS00920	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
EAKF1_RS00925	COG2350	Protein conserved in bacteria
EAKF1_RS00930	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EAKF1_RS00950	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EAKF1_RS00960	COG3436	PFAM IS66 Orf2 family protein
EAKF1_RS00965	COG4372	Transposase
EAKF1_RS00975	COG4608	Belongs to the ABC transporter superfamily
EAKF1_RS00980	COG0444	Belongs to the ABC transporter superfamily
EAKF1_RS00985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EAKF1_RS00990	COG0601	transmembrane transport
EAKF1_RS00995	COG4166	transmembrane transport
EAKF1_RS01000	COG2095	MarC family integral membrane protein
EAKF1_RS01005	COG1454	alcohol dehydrogenase
EAKF1_RS01005	COG1012	belongs to the aldehyde dehydrogenase family
EAKF1_RS01010	COG1435	thymidine kinase activity
EAKF1_RS01020	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EAKF1_RS01025	COG0745	RESPONSE REGULATOR receiver
EAKF1_RS01030	COG1752	Esterase of the alpha-beta hydrolase superfamily
EAKF1_RS01040	COG0788	formyltetrahydrofolate deformylase activity
EAKF1_RS01085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EAKF1_RS01090	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EAKF1_RS01095	COG2181	nitrate reductase activity
EAKF1_RS01100	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EAKF1_RS01105	COG1140	nitrate reductase beta subunit
EAKF1_RS01110	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EAKF1_RS01115	COG2223	nitrite transmembrane transporter activity
EAKF1_RS01125	COG3850	Histidine kinase
EAKF1_RS01130	COG2197	response regulator
EAKF1_RS01135	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
EAKF1_RS01140	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
EAKF1_RS01145	COG0387	Pfam Sodium calcium exchanger
EAKF1_RS01150	COG0641	radical SAM
EAKF1_RS01155	COG0737	Belongs to the 5'-nucleotidase family
EAKF1_RS01180	COG0737	Belongs to the 5'-nucleotidase family
EAKF1_RS01185	COG1525	nuclease
EAKF1_RS01185	COG0737	Belongs to the 5'-nucleotidase family
EAKF1_RS01185	COG4085	toxin activity
EAKF1_RS01190	COG0737	Belongs to the 5'-nucleotidase family
EAKF1_RS01205	COG2912	Transglutaminase-like superfamily
EAKF1_RS01210	COG3094	Invasion gene expression up-regulator, SirB
EAKF1_RS01215	COG2890	protein-(glutamine-N5) methyltransferase activity
EAKF1_RS01240	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EAKF1_RS01245	COG0659	secondary active sulfate transmembrane transporter activity
EAKF1_RS01260	COG0012	GTP binding
EAKF1_RS01265	COG3284	Transcriptional regulator
EAKF1_RS01270	COG2376	Dihydroxyacetone kinase
EAKF1_RS01275	COG1461	Dihydroxyacetone kinase
EAKF1_RS01280	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EAKF1_RS01280	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
EAKF1_RS01280	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAKF1_RS01300	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EAKF1_RS01305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EAKF1_RS01310	COG1120	ATPase activity
EAKF1_RS01320	COG0157	Belongs to the NadC ModD family
EAKF1_RS01335	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
EAKF1_RS01345	COG1619	proteins homologs of microcin C7 resistance protein MccF
EAKF1_RS01355	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EAKF1_RS01365	COG2719	SpoVR family
EAKF1_RS01380	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EAKF1_RS01385	COG3477	response to acidic pH
EAKF1_RS01405	COG4372	Transposase
EAKF1_RS01410	COG3436	PFAM IS66 Orf2 family protein
EAKF1_RS01425	COG0179	Fumarylacetoacetate (FAA) hydrolase
EAKF1_RS01440	COG2894	cell division
EAKF1_RS01490	COG4571	Outer membrane protease
EAKF1_RS01510	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
EAKF1_RS01530	COG0538	isocitrate dehydrogenase activity
EAKF1_RS01535	COG1187	pseudouridine synthase activity
EAKF1_RS01555	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EAKF1_RS01565	COG2205	protein histidine kinase activity
EAKF1_RS01570	COG2850	peptidyl-arginine hydroxylation
EAKF1_RS01585	COG3842	ATPase activity
EAKF1_RS01595	COG1177	transmembrane transport
EAKF1_RS01600	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EAKF1_RS01610	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
EAKF1_RS01620	COG3436	PFAM IS66 Orf2 family protein
EAKF1_RS01625	COG4372	Transposase
EAKF1_RS01630	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EAKF1_RS01640	COG4591	ABC-type transport system involved in lipoprotein release permease component
EAKF1_RS01650	COG4591	ABC-type transport system involved in lipoprotein release permease component
EAKF1_RS01655	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EAKF1_RS01660	COG1376	ErfK ybiS ycfS ynhG family protein
EAKF1_RS01660	COG1388	LysM domain
EAKF1_RS01670	COG1309	transcriptional regulator
EAKF1_RS01675	COG3134	Outer membrane lipoprotein
EAKF1_RS01680	COG1252	NADH dehydrogenase
EAKF1_RS01700	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
EAKF1_RS01705	COG5633	Lipoprotein
EAKF1_RS01710	COG0537	adenosine 5'-monophosphoramidase activity
EAKF1_RS01715	COG1263	PTS System
EAKF1_RS01715	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EAKF1_RS01720	COG0084	hydrolase, TatD family'
EAKF1_RS01725	COG0470	DNA polymerase III
EAKF1_RS01735	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EAKF1_RS01740	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EAKF1_RS01745	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EAKF1_RS01755	COG1028	Short-chain dehydrogenase reductase Sdr
EAKF1_RS01760	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EAKF1_RS01780	COG1399	metal-binding, possibly nucleic acid-binding protein
EAKF1_RS01785	COG0424	maF-like protein
EAKF1_RS01790	COG0564	pseudouridine synthase activity
EAKF1_RS01800	COG1530	ribonuclease E activity
EAKF1_RS01805	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EAKF1_RS01810	COG1256	bacterial-type flagellum assembly
EAKF1_RS01815	COG3951	Flagellar rod assembly protein muramidase FlgJ
EAKF1_RS01815	COG1705	Flagellar rod assembly protein muramidase FlgJ
EAKF1_RS01820	COG1706	bacterial-type flagellum-dependent cell motility
EAKF1_RS01830	COG4786	Flagellar basal body rod
EAKF1_RS01835	COG4787	bacterial-type flagellum-dependent cell motility
EAKF1_RS01840	COG1749	Flagellar hook protein flgE
EAKF1_RS01845	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EAKF1_RS01850	COG1558	bacterial-type flagellum-dependent cell motility
EAKF1_RS01855	COG1815	bacterial-type flagellum-dependent cell motility
EAKF1_RS01860	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
EAKF1_RS01865	COG2747	anti-sigma28 factor FlgM
EAKF1_RS01870	COG3418	PFAM FlgN family protein
EAKF1_RS01875	COG0728	peptidoglycan biosynthetic process
EAKF1_RS01880	COG0673	inositol 2-dehydrogenase activity
EAKF1_RS01890	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EAKF1_RS01935	COG1560	Kdo2-lipid A biosynthetic process
EAKF1_RS01955	COG5645	(Lipo)protein
EAKF1_RS01960	COG2943	transferase activity, transferring hexosyl groups
EAKF1_RS01985	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EAKF1_RS01990	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EAKF1_RS02020	COG2197	response regulator
EAKF1_RS02035	COG1462	curli production assembly transport component CsgG
EAKF1_RS02045	COG3381	protein complex oligomerization
EAKF1_RS02070	COG1702	phosphate starvation-inducible protein PhoH
EAKF1_RS02095	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EAKF1_RS02105	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EAKF1_RS02105	COG0506	proline dehydrogenase activity
EAKF1_RS02105	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EAKF1_RS02145	COG3381	protein complex oligomerization
EAKF1_RS02150	COG0243	molybdopterin cofactor binding
EAKF1_RS02155	COG3005	denitrification pathway
EAKF1_RS02160	COG0745	RESPONSE REGULATOR receiver
EAKF1_RS02165	COG1879	ABC-type sugar transport system periplasmic component
EAKF1_RS02170	COG0784	Response regulator, receiver
EAKF1_RS02170	COG2205	protein histidine kinase activity
EAKF1_RS02170	COG2198	Histidine kinase
EAKF1_RS02175	COG0348	domain, Protein
EAKF1_RS02190	COG1278	Cold shock
EAKF1_RS02195	COG1278	Cold shock
EAKF1_RS02215	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EAKF1_RS02220	COG1596	polysaccharide export
EAKF1_RS02225	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EAKF1_RS02230	COG0489	protein tyrosine kinase activity
EAKF1_RS02230	COG3206	protein involved in exopolysaccharide biosynthesis
EAKF1_RS02245	COG1294	oxidase, subunit
EAKF1_RS02250	COG1271	oxidase subunit
EAKF1_RS02255	COG1773	rubredoxin
EAKF1_RS02260	COG1999	signal sequence binding
EAKF1_RS02265	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EAKF1_RS02270	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
EAKF1_RS02275	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
EAKF1_RS02280	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
EAKF1_RS02315	COG5301	cellulose 1,4-beta-cellobiosidase activity
EAKF1_RS02415	COG4695	Portal protein
EAKF1_RS02450	COG3772	lysozyme
EAKF1_RS02475	COG0484	heat shock protein binding
EAKF1_RS02485	COG1403	HNH endonuclease
EAKF1_RS02525	COG1846	Transcriptional regulator
EAKF1_RS02530	COG1484	DNA-dependent DNA replication
EAKF1_RS02535	COG1846	Transcriptional regulator
EAKF1_RS02550	COG1396	sequence-specific DNA binding
EAKF1_RS02590	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EAKF1_RS02605	COG0670	Belongs to the BI1 family
EAKF1_RS02610	COG2920	part of a sulfur-relay system
EAKF1_RS02615	COG1254	Belongs to the acylphosphatase family
EAKF1_RS02630	COG1832	CoA-binding protein
EAKF1_RS02650	COG0210	DNA helicase
EAKF1_RS02655	COG3304	Inner membrane component domain
EAKF1_RS02660	COG1289	transmembrane transporter activity
EAKF1_RS02665	COG3070	regulator of competence-specific genes
EAKF1_RS02690	COG1067	ATP-dependent peptidase activity
EAKF1_RS02700	COG3130	regulation of translation
EAKF1_RS02705	COG4372	Transposase
EAKF1_RS02710	COG3436	PFAM IS66 Orf2 family protein
EAKF1_RS02720	COG3009	Protein conserved in bacteria
EAKF1_RS02725	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EAKF1_RS02725	COG3008	intermembrane lipid transfer
EAKF1_RS02730	COG2995	paraquat-inducible protein a
EAKF1_RS02735	COG0488	(ABC) transporter
EAKF1_RS02745	COG0633	Ferredoxin
EAKF1_RS02745	COG3217	Mosc domain protein beta barrel domain protein
EAKF1_RS02760	COG0308	aminopeptidase N
EAKF1_RS02785	COG1448	Aminotransferase
EAKF1_RS02790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EAKF1_RS02795	COG3108	Peptidase M15
EAKF1_RS02810	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
EAKF1_RS02820	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EAKF1_RS02825	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EAKF1_RS02830	COG3173	Aminoglycoside phosphotransferase
EAKF1_RS02845	COG3214	Protein conserved in bacteria
EAKF1_RS02860	COG2333	competence protein COMEC
EAKF1_RS02860	COG0658	competence protein
EAKF1_RS02870	COG0539	negative regulation of cytoplasmic translation
EAKF1_RS02890	COG1944	ATP diphosphatase activity
EAKF1_RS02895	COG2116	formate transmembrane transporter activity
EAKF1_RS02900	COG1882	Formate acetyltransferase
EAKF1_RS02920	COG4695	Portal protein
EAKF1_RS02980	COG4974	Belongs to the 'phage' integrase family
EAKF1_RS02985	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EAKF1_RS02995	COG3436	PFAM IS66 Orf2 family protein
EAKF1_RS03000	COG4372	Transposase
EAKF1_RS03005	COG0531	amino acid
EAKF1_RS03015	COG1335	isochorismatase
EAKF1_RS03020	COG3302	dmso reductase anchor subunit
EAKF1_RS03025	COG0437	4 iron, 4 sulfur cluster binding
EAKF1_RS03030	COG0243	molybdopterin cofactor binding
EAKF1_RS03040	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EAKF1_RS03050	COG1674	ftsk spoiiie
EAKF1_RS03050	COG1178	ABC-type Fe3 transport system permease component
EAKF1_RS03055	COG1522	sequence-specific DNA binding
EAKF1_RS03060	COG0492	ferredoxin-NADP+ reductase activity
EAKF1_RS03065	COG4988	ABC transporter
EAKF1_RS03070	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EAKF1_RS03090	COG0542	response to heat
EAKF1_RS03100	COG1278	Cold shock
EAKF1_RS03110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAKF1_RS03115	COG2990	Protein conserved in bacteria
EAKF1_RS03120	COG3593	DNA synthesis involved in DNA repair
EAKF1_RS03140	COG2431	L-lysine efflux transmembrane transporter activity
EAKF1_RS03150	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EAKF1_RS03155	COG0028	Belongs to the TPP enzyme family
EAKF1_RS03160	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
EAKF1_RS03165	COG0702	epimerase
EAKF1_RS03170	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EAKF1_RS03175	COG3023	N-Acetylmuramoyl-L-alanine amidase
EAKF1_RS03190	COG1126	abc transporter atp-binding protein
EAKF1_RS03195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAKF1_RS03200	COG4215	(ABC) transporter
EAKF1_RS03205	COG4160	amino acid transport
EAKF1_RS03210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAKF1_RS03225	COG1177	transmembrane transport
EAKF1_RS03230	COG1176	ABC-type spermidine putrescine transport system, permease component I
EAKF1_RS03235	COG3842	ATPase activity
EAKF1_RS03240	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EAKF1_RS03260	COG0778	Nitroreductase
EAKF1_RS03270	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EAKF1_RS03285	COG3226	Transcriptional regulator
EAKF1_RS03290	COG0738	Major facilitator superfamily
EAKF1_RS03295	COG0561	phosphatase activity
EAKF1_RS03305	COG2814	Major facilitator Superfamily
EAKF1_RS03310	COG0671	phosphoesterase, PA-phosphatase related
EAKF1_RS03315	COG1349	DNA-binding transcription factor activity
EAKF1_RS03320	COG1686	Belongs to the peptidase S11 family
EAKF1_RS03340	COG1413	lyase activity
EAKF1_RS03350	COG2200	EAL domain
EAKF1_RS03365	COG0747	negative chemotaxis
EAKF1_RS03375	COG1446	asparaginase
EAKF1_RS03380	COG0303	'Molybdopterin
EAKF1_RS03385	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EAKF1_RS03395	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EAKF1_RS03400	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EAKF1_RS03405	COG1882	Formate acetyltransferase
EAKF1_RS03410	COG0561	phosphatase activity
EAKF1_RS03415	COG0488	(ABC) transporter
EAKF1_RS03420	COG1376	ErfK ybiS ycfS ynhG family protein
EAKF1_RS03425	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EAKF1_RS03430	COG1321	iron dependent repressor
EAKF1_RS03440	COG2194	sulfuric ester hydrolase activity
EAKF1_RS03445	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EAKF1_RS03450	COG5006	permease, DMT superfamily
EAKF1_RS03465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAKF1_RS03470	COG0765	amino acid transport
EAKF1_RS03475	COG1126	abc transporter atp-binding protein
EAKF1_RS03490	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EAKF1_RS03500	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EAKF1_RS03505	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EAKF1_RS03510	COG1199	ATP-dependent helicase activity
EAKF1_RS03520	COG0513	Belongs to the DEAD box helicase family
EAKF1_RS03525	COG1309	transcriptional regulator
EAKF1_RS03535	COG1131	(ABC) transporter
EAKF1_RS03540	COG0842	Transport permease protein
EAKF1_RS03545	COG0842	Transport permease protein
EAKF1_RS03565	COG0670	Belongs to the BI1 family
EAKF1_RS03570	COG0670	Belongs to the BI1 family
EAKF1_RS03575	COG2194	sulfuric ester hydrolase activity
EAKF1_RS03580	COG0670	Belongs to the BI1 family
EAKF1_RS03585	COG0314	molybdopterin synthase activity
EAKF1_RS03590	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EAKF1_RS03600	COG0521	Mo-molybdopterin cofactor biosynthetic process
EAKF1_RS03615	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EAKF1_RS03625	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EAKF1_RS03630	COG2226	methyltransferase
EAKF1_RS03645	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EAKF1_RS03650	COG1881	PFAM PEBP family protein
EAKF1_RS03655	COG2267	carboxylic ester hydrolase activity
EAKF1_RS03675	COG0583	DNA-binding transcription factor activity
EAKF1_RS03685	COG0561	phosphatase activity
EAKF1_RS03695	COG4149	molybdate abc transporter
EAKF1_RS03700	COG0725	ABC transporter, periplasmic molybdate-binding protein
EAKF1_RS03710	COG2005	Transcriptional regulator
EAKF1_RS03710	COG3585	molybdate ion transport
EAKF1_RS03720	COG1119	ATPase activity
EAKF1_RS03725	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EAKF1_RS03730	COG1085	galactose-1-phosphate uridylyltransferase
EAKF1_RS03740	COG2017	converts alpha-aldose to the beta-anomer
EAKF1_RS03760	COG1486	melibiose metabolic process
EAKF1_RS03765	COG1917	Cupin 2, conserved barrel domain protein
EAKF1_RS03765	COG2169	Transcriptional regulator
EAKF1_RS03775	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EAKF1_RS03785	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EAKF1_RS03790	COG1230	cation diffusion facilitator family transporter
EAKF1_RS03795	COG3201	nicotinamide mononucleotide transporter
EAKF1_RS03835	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
EAKF1_RS03840	COG2885	chlorophyll binding
EAKF1_RS03850	COG3064	Membrane
EAKF1_RS03855	COG0848	biopolymer transport protein
EAKF1_RS03860	COG0811	peptide transport
EAKF1_RS03865	COG0824	Thioesterase
EAKF1_RS03870	COG3790	cyd operon protein YbgE
EAKF1_RS03875	COG4890	Cyd operon protein YbgT
EAKF1_RS03880	COG1294	oxidase, subunit
EAKF1_RS03885	COG1271	oxidase subunit
EAKF1_RS03900	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EAKF1_RS03910	COG0508	dehydrogenase complex catalyzes the overall conversion of
EAKF1_RS03915	COG0567	Dehydrogenase, E1 component
EAKF1_RS03925	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EAKF1_RS03930	COG1053	succinate dehydrogenase
EAKF1_RS03935	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EAKF1_RS03940	COG2009	succinate dehydrogenase
EAKF1_RS03950	COG0372	Belongs to the citrate synthase family
EAKF1_RS03955	COG3539	Fimbrial protein
EAKF1_RS03965	COG3121	Chaperone
EAKF1_RS03970	COG3539	Fimbrial protein
EAKF1_RS03975	COG3180	Ammonia monooxygenase
EAKF1_RS03990	COG1984	allophanate hydrolase subunit 2
EAKF1_RS03995	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EAKF1_RS04000	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EAKF1_RS04010	COG0415	Belongs to the DNA photolyase family
EAKF1_RS04015	COG3272	Protein of unknown function (DUF1722)
EAKF1_RS04040	COG3209	COG3209 Rhs family protein
EAKF1_RS04070	COG2205	protein histidine kinase activity
EAKF1_RS04075	COG0745	RESPONSE REGULATOR receiver
EAKF1_RS04085	COG1982	Orn Lys Arg decarboxylase major
EAKF1_RS04090	COG0531	amino acid
EAKF1_RS04095	COG0033	Phosphoglucomutase
EAKF1_RS04100	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
EAKF1_RS04105	COG0596	Alpha beta hydrolase
EAKF1_RS04115	COG0716	FMN binding
EAKF1_RS04130	COG0735	belongs to the Fur family
EAKF1_RS04150	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EAKF1_RS04150	COG2190	(PTS) system
EAKF1_RS04150	COG1263	PTS System
EAKF1_RS04160	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EAKF1_RS04165	COG1940	carbohydrate kinase activity
EAKF1_RS04165	COG1846	Transcriptional regulator
EAKF1_RS04170	COG0647	UMP catabolic process
EAKF1_RS04175	COG0367	asparagine synthase
EAKF1_RS04215	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EAKF1_RS04225	COG1702	phosphate starvation-inducible protein PhoH
EAKF1_RS04235	COG4535	Mg2 and Co2 transporter CorC
EAKF1_RS04240	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EAKF1_RS04245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAKF1_RS04250	COG0765	amino acid transport
EAKF1_RS04255	COG0765	amino acid transport
EAKF1_RS04260	COG1126	abc transporter atp-binding protein
EAKF1_RS04275	COG2214	Heat shock protein DnaJ domain protein
EAKF1_RS04285	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
EAKF1_RS04300	COG2888	peptidyl-tyrosine sulfation
EAKF1_RS04310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAKF1_RS04310	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EAKF1_RS04310	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EAKF1_RS04335	COG1609	Transcriptional regulator
EAKF1_RS04350	COG1466	dna polymerase III delta subunit
EAKF1_RS04360	COG0406	alpha-ribazole phosphatase activity
EAKF1_RS04365	COG0799	negative regulation of ribosome biogenesis
EAKF1_RS04375	COG0768	penicillin binding
EAKF1_RS04380	COG0772	Belongs to the SEDS family
EAKF1_RS04385	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EAKF1_RS04390	COG1686	Belongs to the peptidase S11 family
EAKF1_RS04405	COG0583	DNA-binding transcription factor activity
EAKF1_RS04415	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EAKF1_RS04420	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EAKF1_RS04440	COG3069	C4-dicarboxylate transmembrane transporter activity
EAKF1_RS04445	COG4565	transcriptional regulatory protein
EAKF1_RS04450	COG3290	protein histidine kinase activity
EAKF1_RS04455	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
EAKF1_RS04465	COG2301	Belongs to the HpcH HpaI aldolase family
EAKF1_RS04470	COG3051	citrate lyase alpha subunit
EAKF1_RS04485	COG0471	metal ion transport
EAKF1_RS04490	COG3719	Belongs to the RNase T2 family
EAKF1_RS04495	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EAKF1_RS04500	COG0589	response to stress
EAKF1_RS04505	COG3634	alkyl hydroperoxide reductase activity
EAKF1_RS04510	COG0450	alkyl hydroperoxide reductase
EAKF1_RS04515	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EAKF1_RS04520	COG0583	DNA-binding transcription factor activity
EAKF1_RS04525	COG3969	phosphoadenosine phosphosulfate
EAKF1_RS04530	COG1475	DNA binding
EAKF1_RS04535	COG0436	Aminotransferase
EAKF1_RS04540	COG0371	Dehydrogenase
EAKF1_RS04545	COG2879	small protein
EAKF1_RS04550	COG1966	Carbon starvation protein
EAKF1_RS04560	COG1028	Short-chain dehydrogenase reductase Sdr
EAKF1_RS04565	COG3433	isochorismatase activity
EAKF1_RS04565	COG1535	isochorismatase
EAKF1_RS04570	COG1021	2,3-dihydroxybenzoate-AMP ligase
EAKF1_RS04575	COG1169	isochorismate synthase
EAKF1_RS04580	COG4592	Periplasmic binding protein
EAKF1_RS04590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EAKF1_RS04595	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EAKF1_RS04600	COG1120	ATPase activity
EAKF1_RS04605	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
EAKF1_RS04610	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EAKF1_RS04610	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
EAKF1_RS04615	COG3251	PFAM MbtH domain protein
EAKF1_RS04620	COG2382	esterase
EAKF1_RS04625	COG4771	TonB-dependent receptor
EAKF1_RS04630	COG2977	Belongs to the P-Pant transferase superfamily
EAKF1_RS04650	COG2315	Protein conserved in bacteria
EAKF1_RS04655	COG0778	Nitroreductase
EAKF1_RS04660	COG0668	transmembrane transport
EAKF1_RS04665	COG1113	amino acid transport
EAKF1_RS04670	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EAKF1_RS04675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAKF1_RS04680	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAKF1_RS04685	COG1538	Outer membrane efflux protein
EAKF1_RS04690	COG0745	RESPONSE REGULATOR receiver
EAKF1_RS04695	COG5002	protein histidine kinase activity
EAKF1_RS04730	COG1215	transferase activity, transferring glycosyl groups
EAKF1_RS04735	COG4783	chaperone-mediated protein folding
EAKF1_RS04745	COG2207	Transcriptional regulator
EAKF1_RS04760	COG4571	Outer membrane protease
EAKF1_RS04765	COG2207	Transcriptional regulator
EAKF1_RS04770	COG4771	TonB-dependent receptor
EAKF1_RS04785	COG4372	Transposase
EAKF1_RS04790	COG3436	PFAM IS66 Orf2 family protein
EAKF1_RS04895	COG0582	viral genome integration into host DNA
EAKF1_RS04905	COG2197	response regulator
EAKF1_RS04910	COG3539	Fimbrial protein
EAKF1_RS04915	COG3539	Fimbrial protein
EAKF1_RS04920	COG3188	usher protein
EAKF1_RS04930	COG3121	Chaperone
EAKF1_RS04935	COG3539	Fimbrial protein
EAKF1_RS04945	COG2501	S4 domain
EAKF1_RS04950	COG1988	membrane-bound metal-dependent
EAKF1_RS04960	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EAKF1_RS04975	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EAKF1_RS04980	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EAKF1_RS04990	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EAKF1_RS04995	COG4181	ATPase activity
EAKF1_RS05000	COG2755	lipolytic protein G-D-S-L family
EAKF1_RS05005	COG0300	oxidoreductase activity
EAKF1_RS05010	COG3118	belongs to the thioredoxin family
EAKF1_RS05025	COG0390	transport system, permease component
EAKF1_RS05030	COG4619	ABC transporter
EAKF1_RS05035	COG0330	HflC and HflK could
EAKF1_RS05040	COG1585	Membrane protein implicated in regulation of membrane protease activity
EAKF1_RS05050	COG0789	Transcriptional regulator
EAKF1_RS05055	COG0531	amino acid
EAKF1_RS05065	COG2217	Heavy metal translocating P-type atpase
EAKF1_RS05070	COG3735	TraB family
EAKF1_RS05075	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EAKF1_RS05080	COG0737	Belongs to the 5'-nucleotidase family
EAKF1_RS05085	COG2223	nitrite transmembrane transporter activity
EAKF1_RS05090	COG4651	solute:proton antiporter activity
EAKF1_RS05090	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EAKF1_RS05095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EAKF1_RS05130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EAKF1_RS05140	COG2832	Protein of unknown function (DUF454)
EAKF1_RS05145	COG3923	Primosomal replication protein n
EAKF1_RS05160	COG1196	nuclear chromosome segregation
EAKF1_RS05160	COG3264	Mechanosensitive ion channel
EAKF1_RS05165	COG1309	transcriptional regulator
EAKF1_RS05170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAKF1_RS05175	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EAKF1_RS05190	COG0110	maltose O-acetyltransferase activity
EAKF1_RS05200	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EAKF1_RS05205	COG5507	3-demethylubiquinone-9 3-methyltransferase
EAKF1_RS05210	COG4372	Transposase
EAKF1_RS05215	COG3436	PFAM IS66 Orf2 family protein
EAKF1_RS05225	COG3695	enzyme binding
EAKF1_RS05230	COG3126	Type III secretion system lipoprotein chaperone (YscW)
EAKF1_RS05235	COG1946	Acyl-CoA thioesterase
EAKF1_RS05240	COG0004	ammonium transporteR
EAKF1_RS05245	COG0347	Belongs to the P(II) protein family
EAKF1_RS05250	COG1132	(ABC) transporter
EAKF1_RS05255	COG1132	(ABC) transporter
EAKF1_RS05260	COG1522	sequence-specific DNA binding
EAKF1_RS05270	COG4533	DNA binding
EAKF1_RS05280	COG0824	Thioesterase
EAKF1_RS05285	COG1555	photosystem II stabilization
EAKF1_RS05290	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EAKF1_RS05295	COG0776	regulation of translation
EAKF1_RS05300	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EAKF1_RS05325	COG0271	Belongs to the BolA IbaG family
EAKF1_RS05330	COG3056	Lipoprotein
EAKF1_RS05335	COG2223	nitrite transmembrane transporter activity
EAKF1_RS05340	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EAKF1_RS05345	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EAKF1_RS05350	COG1845	cytochrome c oxidase, subunit III
EAKF1_RS05355	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EAKF1_RS05365	COG1473	amidohydrolase
EAKF1_RS05380	COG0583	DNA-binding transcription factor activity
EAKF1_RS05385	COG2814	Major facilitator Superfamily
EAKF1_RS05395	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EAKF1_RS05400	COG0693	protein deglycase activity
EAKF1_RS05415	COG0142	geranyltranstransferase activity
EAKF1_RS05425	COG0667	Aldo Keto reductase
EAKF1_RS05435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EAKF1_RS05440	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EAKF1_RS05455	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EAKF1_RS05455	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EAKF1_RS05465	COG4238	major outer membrane lipoprotein
EAKF1_RS05470	COG3248	Nucleoside-binding outer membrane protein
EAKF1_RS05480	COG1403	HNH endonuclease
EAKF1_RS05485	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EAKF1_RS05490	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EAKF1_RS05495	COG1862	Preprotein translocase
EAKF1_RS05515	COG0366	Alpha amylase catalytic
EAKF1_RS05520	COG1113	amino acid transport
EAKF1_RS05525	COG1114	Component of the transport system for branched-chain amino acids
EAKF1_RS05530	COG5002	protein histidine kinase activity
EAKF1_RS05535	COG0745	RESPONSE REGULATOR receiver
EAKF1_RS05540	COG0420	3'-5' exonuclease activity
EAKF1_RS05545	COG0419	ATPase involved in DNA repair
EAKF1_RS05550	COG1940	carbohydrate kinase activity
EAKF1_RS05570	COG4126	flavin adenine dinucleotide binding
EAKF1_RS05590	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EAKF1_RS05595	COG3706	GGDEF domain
EAKF1_RS05605	COG1785	Belongs to the alkaline phosphatase family
EAKF1_RS05620	COG1181	Belongs to the D-alanine--D-alanine ligase family
EAKF1_RS05640	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
EAKF1_RS05650	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EAKF1_RS05655	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EAKF1_RS05660	COG3468	outer membrane autotransporter barrel domain protein
EAKF1_RS05675	COG3468	outer membrane autotransporter barrel domain protein
EAKF1_RS05680	COG0113	porphobilinogen synthase activity
EAKF1_RS05685	COG2175	clavaminate synthase activity
EAKF1_RS05690	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EAKF1_RS05700	COG4521	taurine ABC transporter
EAKF1_RS05720	COG3122	Protein conserved in bacteria
EAKF1_RS05730	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EAKF1_RS05735	COG2079	MmgE PrpD family protein
EAKF1_RS05740	COG0372	Belongs to the citrate synthase family
EAKF1_RS05745	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EAKF1_RS05750	COG3829	transcription factor binding
EAKF1_RS05765	COG1280	lysine exporter protein (LysE YggA)
EAKF1_RS05780	COG0549	Belongs to the carbamate kinase family
EAKF1_RS05790	COG1304	FMN binding
EAKF1_RS05795	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EAKF1_RS05805	COG0666	response to abiotic stimulus
EAKF1_RS05815	COG0583	DNA-binding transcription factor activity
EAKF1_RS05820	COG2200	EAL domain
EAKF1_RS05820	COG2771	luxR family
EAKF1_RS05830	COG0667	Aldo Keto reductase
EAKF1_RS05840	COG1556	Lactate utilization protein
EAKF1_RS05845	COG1139	Iron-sulfur cluster binding protein
EAKF1_RS05850	COG0247	lactate metabolic process
EAKF1_RS05855	COG1620	l-lactate permease
EAKF1_RS05860	COG2207	Transcriptional regulator
EAKF1_RS05865	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EAKF1_RS05875	COG3059	membrane
EAKF1_RS05895	COG3436	PFAM IS66 Orf2 family protein
EAKF1_RS05900	COG4372	Transposase
EAKF1_RS05910	COG0500	methyltransferase
EAKF1_RS05930	COG2207	Transcriptional regulator
EAKF1_RS06005	COG0582	viral genome integration into host DNA
EAKF1_RS06025	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EAKF1_RS06045	COG2195	Cleaves the N-terminal amino acid of tripeptides
EAKF1_RS06065	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EAKF1_RS06070	COG0454	-acetyltransferase
EAKF1_RS06085	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EAKF1_RS06115	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EAKF1_RS06120	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EAKF1_RS06145	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EAKF1_RS06150	COG4786	Flagellar basal body rod
EAKF1_RS06150	COG1256	bacterial-type flagellum assembly
EAKF1_RS06225	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EAKF1_RS06245	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EAKF1_RS06255	COG1677	Flagellar hook-basal body complex protein FliE
EAKF1_RS06285	COG1987	bacterial-type flagellum assembly
EAKF1_RS06310	COG0791	NLP P60 protein
EAKF1_RS06315	COG3034	peptidoglycan biosynthetic process
EAKF1_RS06320	COG0121	glutamine amidotransferase
EAKF1_RS06330	COG1960	acyl-CoA dehydrogenase activity
EAKF1_RS06340	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EAKF1_RS06360	COG5433	transposase activity
EAKF1_RS06370	COG3209	COG3209 Rhs family protein
EAKF1_RS06400	COG3157	Type VI secretion system effector, Hcp
EAKF1_RS06405	COG4104	PAAR repeat-containing protein
EAKF1_RS06425	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EAKF1_RS06435	COG2226	methyltransferase
EAKF1_RS06445	COG0741	lytic transglycosylase activity
EAKF1_RS06445	COG1388	LysM domain
EAKF1_RS06455	COG0583	DNA-binding transcription factor activity
EAKF1_RS06460	COG0656	L-ascorbic acid biosynthetic process
EAKF1_RS06495	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EAKF1_RS06505	COG2011	ABC-type metal ion transport system permease component
EAKF1_RS06510	COG1464	Belongs to the NlpA lipoprotein family
EAKF1_RS06520	COG1720	tRNA m6t6A37 methyltransferase activity
EAKF1_RS06530	COG3015	lipoprotein NlpE involved in copper resistance
EAKF1_RS06535	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EAKF1_RS06540	COG4681	YaeQ
EAKF1_RS06550	COG4568	rho-dependent transcription termination
EAKF1_RS06555	COG0037	tRNA processing
EAKF1_RS06560	COG0346	lactoylglutathione lyase activity
EAKF1_RS06570	COG0587	DNA-directed DNA polymerase activity
EAKF1_RS06595	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EAKF1_RS06600	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
EAKF1_RS06610	COG0750	zinc metalloprotease
EAKF1_RS06615	COG0575	Belongs to the CDS family
EAKF1_RS06620	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EAKF1_RS06625	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EAKF1_RS06650	COG0024	Methionine aminopeptidase
EAKF1_RS06665	COG1408	metallophosphoesterase
EAKF1_RS06675	COG3835	regulator
EAKF1_RS06680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EAKF1_RS06695	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EAKF1_RS06700	COG2860	membrane
EAKF1_RS06720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EAKF1_RS06725	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EAKF1_RS06730	COG1120	ATPase activity
EAKF1_RS06735	COG4774	siderophore transport
EAKF1_RS06740	COG3539	Fimbrial protein
EAKF1_RS06750	COG3121	Chaperone
EAKF1_RS06760	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EAKF1_RS06770	COG1643	Atp-dependent helicase
EAKF1_RS06775	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EAKF1_RS06785	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EAKF1_RS06795	COG0617	tRNA 3'-terminal CCA addition
EAKF1_RS06800	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EAKF1_RS06810	COG3121	Chaperone
EAKF1_RS06815	COG3188	usher protein
EAKF1_RS06820	COG3539	Fimbrial protein
EAKF1_RS06830	COG3539	Fimbrial protein
EAKF1_RS06845	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EAKF1_RS06850	COG5464	transposase or invertase
EAKF1_RS06860	COG0726	polysaccharide deacetylase
EAKF1_RS06865	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAKF1_RS06870	COG0842	Transport permease protein
EAKF1_RS06875	COG1131	(ABC) transporter
EAKF1_RS06880	COG0288	reversible hydration of carbon dioxide
EAKF1_RS06885	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EAKF1_RS06890	COG4993	Dehydrogenase
EAKF1_RS06895	COG2132	Multicopper oxidase
EAKF1_RS06935	COG1049	propionate catabolic process, 2-methylcitrate cycle
EAKF1_RS06940	COG3064	Membrane
EAKF1_RS06950	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EAKF1_RS06955	COG0508	dehydrogenase complex catalyzes the overall conversion of
EAKF1_RS06960	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EAKF1_RS06965	COG2186	Transcriptional regulator
EAKF1_RS06970	COG1113	amino acid transport
EAKF1_RS06975	COG3725	Membrane protein required for beta-lactamase induction
EAKF1_RS06980	COG3023	N-Acetylmuramoyl-L-alanine amidase
EAKF1_RS06985	COG0157	Belongs to the NadC ModD family
EAKF1_RS06995	COG4969	Belongs to the N-Me-Phe pilin family
EAKF1_RS07000	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EAKF1_RS07005	COG1459	type II secretion system
EAKF1_RS07015	COG0237	dephospho-CoA kinase activity
EAKF1_RS07035	COG0494	nUDIX hydrolase
EAKF1_RS07055	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EAKF1_RS07060	COG0849	cell division
EAKF1_RS07065	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EAKF1_RS07070	COG1181	Belongs to the D-alanine--D-alanine ligase family
EAKF1_RS07085	COG0772	Belongs to the SEDS family
EAKF1_RS07100	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EAKF1_RS07105	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EAKF1_RS07110	COG0768	penicillin binding
EAKF1_RS07115	COG3116	cell division
EAKF1_RS07130	COG1609	Transcriptional regulator
EAKF1_RS07140	COG0440	acetolactate synthase activity
EAKF1_RS07145	COG0028	Belongs to the TPP enzyme family
EAKF1_RS07150	COG0583	DNA-binding transcription factor activity
EAKF1_RS07190	COG4143	(ABC) transporter
EAKF1_RS07195	COG1178	ABC-type Fe3 transport system permease component
EAKF1_RS07205	COG0586	Pfam SNARE associated Golgi protein
EAKF1_RS07210	COG4977	sequence-specific DNA binding
EAKF1_RS07225	COG0235	Class ii aldolase
EAKF1_RS07230	COG0417	DNA replication proofreading
EAKF1_RS07240	COG0564	pseudouridine synthase activity
EAKF1_RS07245	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EAKF1_RS07255	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EAKF1_RS07295	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EAKF1_RS07300	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EAKF1_RS07300	COG0475	glutathione-regulated potassium exporter activity
EAKF1_RS07310	COG2271	Major facilitator Superfamily
EAKF1_RS07315	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
EAKF1_RS07320	COG0644	oxidoreductase
EAKF1_RS07375	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EAKF1_RS07380	COG0505	Belongs to the CarA family
EAKF1_RS07410	COG1047	Peptidyl-prolyl cis-trans
EAKF1_RS07425	COG0196	riboflavin kinase activity
EAKF1_RS07445	COG0583	DNA-binding transcription factor activity
EAKF1_RS07450	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EAKF1_RS07460	COG3119	arylsulfatase activity
EAKF1_RS07490	COG4735	regulation of single-species biofilm formation
EAKF1_RS07495	COG1584	GPR1 FUN34 yaaH family protein
EAKF1_RS07505	COG0521	Mo-molybdopterin cofactor biosynthetic process
EAKF1_RS07515	COG1115	amino acid carrier protein
EAKF1_RS07535	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EAKF1_RS07545	COG0527	aspartate kinase activity
EAKF1_RS07545	COG0460	homoserine dehydrogenase
EAKF1_RS07555	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
EAKF1_RS07565	COG0745	RESPONSE REGULATOR receiver
EAKF1_RS07570	COG4452	Inner membrane protein CreD
EAKF1_RS07575	COG2205	protein histidine kinase activity
EAKF1_RS07580	COG0745	RESPONSE REGULATOR receiver
EAKF1_RS07585	COG3045	CreA protein
EAKF1_RS07590	COG3708	Transcriptional regulator
EAKF1_RS07590	COG2207	Transcriptional regulator
EAKF1_RS07610	COG0741	lytic transglycosylase activity
EAKF1_RS07615	COG0488	(ABC) transporter
EAKF1_RS07620	COG1056	cytidyltransferase-related domain
EAKF1_RS07620	COG3172	ATPase kinase involved in NAD metabolism
EAKF1_RS07625	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EAKF1_RS07630	COG0560	Phosphoserine phosphatase
EAKF1_RS07635	COG3726	membrane protein affecting hemolysin expression
EAKF1_RS07640	COG0095	Lipoate-protein ligase
EAKF1_RS07645	COG3550	peptidyl-serine autophosphorylation
EAKF1_RS07675	COG1328	CTP reductase activity
EAKF1_RS07680	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EAKF1_RS07685	COG0084	hydrolase, TatD family'
EAKF1_RS07690	COG4667	esterase of the alpha-beta hydrolase superfamily
EAKF1_RS07700	COG2823	Periplasmic or secreted lipoprotein
EAKF1_RS07735	COG1403	HNH endonuclease
EAKF1_RS07745	COG1846	Transcriptional regulator
EAKF1_RS07785	COG5532	Uncharacterized conserved protein (DUF2303)
EAKF1_RS07790	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
EAKF1_RS07810	COG3436	PFAM IS66 Orf2 family protein
EAKF1_RS07815	COG4372	Transposase
EAKF1_RS07820	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EAKF1_RS07840	COG1011	Hydrolase
EAKF1_RS07845	COG0456	acetyltransferase
EAKF1_RS07850	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
EAKF1_RS07880	COG4114	ferric iron reductase
EAKF1_RS07885	COG2197	response regulator
EAKF1_RS07890	COG2197	response regulator
EAKF1_RS07895	COG2966	Psort location CytoplasmicMembrane, score
EAKF1_RS07910	COG1484	DNA-dependent DNA replication
EAKF1_RS07925	COG1063	alcohol dehydrogenase
EAKF1_RS07930	COG1802	Transcriptional regulator
EAKF1_RS07935	COG2271	Major facilitator Superfamily
EAKF1_RS07940	COG0840	transmembrane signaling receptor activity
EAKF1_RS07945	COG1966	Carbon starvation protein
EAKF1_RS07950	COG2879	small protein
EAKF1_RS07955	COG0523	cobalamin synthesis protein
EAKF1_RS07965	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
EAKF1_RS07970	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EAKF1_RS08000	COG2733	membrane
EAKF1_RS08005	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
EAKF1_RS08010	COG1924	4 iron, 4 sulfur cluster binding
EAKF1_RS08025	COG3366	ferrous iron transmembrane transporter activity
EAKF1_RS08030	COG0700	Nucleoside recognition
EAKF1_RS08035	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EAKF1_RS08040	COG1757	Na H antiporter
EAKF1_RS08050	COG3284	Transcriptional regulator
EAKF1_RS08055	COG3960	tartronate-semialdehyde synthase activity
EAKF1_RS08060	COG3622	Belongs to the hyi family
EAKF1_RS08065	COG2084	Dehydrogenase
EAKF1_RS08070	COG1929	Belongs to the glycerate kinase type-1 family
EAKF1_RS08100	COG2376	Dihydroxyacetone kinase
EAKF1_RS08105	COG1461	Dihydroxyacetone kinase
EAKF1_RS08110	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAKF1_RS08110	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EAKF1_RS08115	COG3518	anti-sigma factor antagonist activity
EAKF1_RS08130	COG2186	Transcriptional regulator
EAKF1_RS08140	COG0246	Mannitol dehydrogenase
EAKF1_RS08155	COG2610	gluconate transmembrane transporter activity
EAKF1_RS08160	COG3539	Fimbrial protein
EAKF1_RS08165	COG3539	Fimbrial protein
EAKF1_RS08170	COG3539	Fimbrial protein
EAKF1_RS08175	COG3188	usher protein
EAKF1_RS08180	COG3121	Chaperone
EAKF1_RS08185	COG3539	Fimbrial protein
EAKF1_RS08195	COG4974	Belongs to the 'phage' integrase family
EAKF1_RS08200	COG0582	viral genome integration into host DNA
EAKF1_RS08205	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
EAKF1_RS08220	COG3436	PFAM IS66 Orf2 family protein
EAKF1_RS08225	COG4372	Transposase
EAKF1_RS08285	COG0582	viral genome integration into host DNA
EAKF1_RS08295	COG1064	alcohol dehydrogenase
EAKF1_RS08300	COG0433	COG0433 Predicted ATPase
EAKF1_RS08305	COG0795	lipopolysaccharide-transporting ATPase activity
EAKF1_RS08310	COG0795	lipopolysaccharide-transporting ATPase activity
EAKF1_RS08320	COG2927	DNA polymerase III (CHI subunit)
EAKF1_RS08325	COG0525	valine-tRNA ligase activity
EAKF1_RS08335	COG0456	acetyltransferase
EAKF1_RS08340	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
EAKF1_RS08355	COG2731	YhcH YjgK YiaL family protein
EAKF1_RS08375	COG0251	oxidation-reduction process
EAKF1_RS08385	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EAKF1_RS08390	COG1609	Transcriptional regulator
EAKF1_RS08395	COG1263	PTS System
EAKF1_RS08395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EAKF1_RS08400	COG0366	Alpha amylase catalytic
EAKF1_RS08410	COG1328	CTP reductase activity
EAKF1_RS08415	COG0602	queuosine metabolic process
EAKF1_RS08425	COG3783	Cytochrome b(562)
EAKF1_RS08430	COG0312	modulator of DNA gyrase
EAKF1_RS08440	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EAKF1_RS08455	COG1172	Belongs to the binding-protein-dependent transport system permease family
EAKF1_RS08460	COG1172	Belongs to the binding-protein-dependent transport system permease family
EAKF1_RS08465	COG1129	ABC transporter
EAKF1_RS08470	COG1879	ABC-type sugar transport system periplasmic component
EAKF1_RS08475	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EAKF1_RS08480	COG2105	PFAM AIG2 family protein
EAKF1_RS08485	COG2911	Protein conserved in bacteria
EAKF1_RS08490	COG0729	surface antigen
EAKF1_RS08505	COG1253	flavin adenine dinucleotide binding
EAKF1_RS08515	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
EAKF1_RS08525	COG1218	3'(2'),5'-bisphosphate nucleotidase
EAKF1_RS08530	COG0737	Belongs to the 5'-nucleotidase family
EAKF1_RS08540	COG0697	spore germination
EAKF1_RS08560	COG1113	amino acid transport
EAKF1_RS08565	COG0545	Peptidyl-prolyl cis-trans isomerase
EAKF1_RS08570	COG3061	Opacity-associated protein A
EAKF1_RS08575	COG1309	transcriptional regulator
EAKF1_RS08590	COG1024	Enoyl-CoA hydratase
EAKF1_RS08595	COG4670	ketone body catabolic process
EAKF1_RS08600	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EAKF1_RS08615	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EAKF1_RS08655	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAKF1_RS08660	COG3414	Phosphotransferase system galactitol-specific IIB component
EAKF1_RS08675	COG4372	Transposase
EAKF1_RS08680	COG3436	PFAM IS66 Orf2 family protein
EAKF1_RS08700	COG1073	alpha beta
EAKF1_RS08705	COG3650	response to hydrogen peroxide
EAKF1_RS08715	COG1960	acyl-CoA dehydrogenase activity
EAKF1_RS08720	COG0754	glutathionylspermidine amidase activity
EAKF1_RS08725	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EAKF1_RS08730	COG0557	exoribonuclease II activity
EAKF1_RS08745	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
EAKF1_RS08750	COG0330	HflC and HflK could
EAKF1_RS08755	COG0330	HflC and HflK could
EAKF1_RS08760	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EAKF1_RS08775	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EAKF1_RS08780	COG0860	N-Acetylmuramoyl-L-alanine amidase
EAKF1_RS08785	COG0802	atpase or kinase
EAKF1_RS08790	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EAKF1_RS08790	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EAKF1_RS08795	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EAKF1_RS08825	COG1511	domain protein
EAKF1_RS08825	COG3264	Mechanosensitive ion channel
EAKF1_RS08840	COG0531	amino acid
EAKF1_RS08850	COG1053	succinate dehydrogenase
EAKF1_RS08855	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EAKF1_RS08870	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EAKF1_RS08875	COG3040	lipid binding
EAKF1_RS08880	COG2076	Multidrug Resistance protein
EAKF1_RS08890	COG5510	response to toxic substance
EAKF1_RS08900	COG1509	lysine 2,3-aminomutase activity
EAKF1_RS08925	COG0531	amino acid
EAKF1_RS08930	COG3030	protein affecting phage T7 exclusion by the F plasmid
EAKF1_RS08935	COG1027	Aspartate ammonia-lyase
EAKF1_RS08940	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EAKF1_RS08950	COG4232	protein-disulfide reductase activity
EAKF1_RS08955	COG1309	transcriptional regulator
EAKF1_RS09185	COG2388	GCN5-related N-acetyl-transferase
EAKF1_RS09190	COG3592	Divergent 4Fe-4S mono-cluster
EAKF1_RS09195	COG3290	protein histidine kinase activity
EAKF1_RS09200	COG4565	transcriptional regulatory protein
EAKF1_RS09205	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EAKF1_RS09210	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EAKF1_RS09210	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EAKF1_RS09215	COG3647	Membrane
EAKF1_RS09220	COG1982	Orn Lys Arg decarboxylase major
EAKF1_RS09225	COG2207	Transcriptional regulator
EAKF1_RS09230	COG0531	amino acid
EAKF1_RS09235	COG2194	sulfuric ester hydrolase activity
EAKF1_RS09240	COG0745	RESPONSE REGULATOR receiver
EAKF1_RS09245	COG0642	Histidine kinase
EAKF1_RS09260	COG2824	Alkylphosphonate utilization operon protein PhnA
EAKF1_RS09265	COG2764	glyoxalase bleomycin resistance protein dioxygenase
EAKF1_RS09285	COG1028	Short-chain dehydrogenase reductase Sdr
EAKF1_RS09300	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EAKF1_RS09305	COG4670	ketone body catabolic process
EAKF1_RS09310	COG0477	Major facilitator Superfamily
EAKF1_RS09320	COG1028	Short-chain dehydrogenase reductase Sdr
EAKF1_RS09355	COG5301	cellulose 1,4-beta-cellobiosidase activity
EAKF1_RS09365	COG4626	Terminase
EAKF1_RS09365	COG1802	Transcriptional regulator
EAKF1_RS09395	COG5532	Uncharacterized conserved protein (DUF2303)
EAKF1_RS09400	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
EAKF1_RS09440	COG0698	ribose 5-phosphate isomerase
EAKF1_RS09445	COG1737	Transcriptional regulator
EAKF1_RS09450	COG1879	ABC-type sugar transport system periplasmic component
EAKF1_RS09455	COG1129	ABC transporter
EAKF1_RS09460	COG1172	Belongs to the binding-protein-dependent transport system permease family
EAKF1_RS09465	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EAKF1_RS09470	COG1940	carbohydrate kinase activity
EAKF1_RS09475	COG2015	COG2015, Alkyl sulfatase and related hydrolases
EAKF1_RS09485	COG1566	PFAM secretion protein HlyD family protein
EAKF1_RS09490	COG1289	transmembrane transporter activity
EAKF1_RS09500	COG3383	formate dehydrogenase (NAD+) activity
EAKF1_RS09505	COG3383	formate dehydrogenase (NAD+) activity
EAKF1_RS09515	COG0601	transmembrane transport
EAKF1_RS09525	COG0444	Belongs to the ABC transporter superfamily
EAKF1_RS09530	COG4608	Belongs to the ABC transporter superfamily
EAKF1_RS09535	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
EAKF1_RS09540	COG1301	dicarboxylic acid transport
EAKF1_RS09545	COG4235	cytochrome complex assembly
EAKF1_RS09550	COG3088	subunit of a heme lyase
EAKF1_RS09555	COG1138	Cytochrome C-type biogenesis protein
EAKF1_RS09560	COG3301	Polysulphide reductase, NrfD
EAKF1_RS09565	COG0437	4 iron, 4 sulfur cluster binding
EAKF1_RS09570	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
EAKF1_RS09580	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EAKF1_RS09585	COG3162	membrane
EAKF1_RS09595	COG0025	NhaP-type Na H and K H
EAKF1_RS09600	COG2252	PERMEase
EAKF1_RS09605	COG0789	Transcriptional regulator
EAKF1_RS09610	COG2207	Transcriptional regulator
EAKF1_RS09615	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EAKF1_RS09635	COG0629	single-stranded DNA binding
EAKF1_RS09640	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EAKF1_RS09645	COG2315	Protein conserved in bacteria
EAKF1_RS09650	COG0432	Pfam Uncharacterised protein family UPF0047
EAKF1_RS09655	COG3700	Belongs to the class B bacterial acid phosphatase family
EAKF1_RS09670	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EAKF1_RS09675	COG0471	metal ion transport
EAKF1_RS09680	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EAKF1_RS09685	COG0045	succinate-CoA ligase (ADP-forming) activity
EAKF1_RS09690	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EAKF1_RS09700	COG0567	Dehydrogenase, E1 component
EAKF1_RS09705	COG1448	Aminotransferase
EAKF1_RS09715	COG0305	Participates in initiation and elongation during chromosome replication
EAKF1_RS09720	COG0604	alcohol dehydrogenase
EAKF1_RS09730	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EAKF1_RS09755	COG5301	cellulose 1,4-beta-cellobiosidase activity
EAKF1_RS09765	COG3772	lysozyme
EAKF1_RS09800	COG0735	belongs to the Fur family
EAKF1_RS09805	COG3237	CsbD-like
EAKF1_RS09810	COG0534	Mate efflux family protein
EAKF1_RS09830	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EAKF1_RS09860	COG3842	ATPase activity
EAKF1_RS09870	COG2182	Extracellular solute-binding protein
EAKF1_RS09875	COG1175	transmembrane transport
EAKF1_RS09880	COG3833	ABC-type maltose transport systems, permease component
EAKF1_RS09920	COG0527	aspartate kinase activity
EAKF1_RS09940	COG1187	pseudouridine synthase activity
EAKF1_RS09980	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EAKF1_RS09990	COG1283	sodium-dependent phosphate transmembrane transporter activity
EAKF1_RS09995	COG1410	methionine synthase
EAKF1_RS09995	COG0646	methionine synthase
EAKF1_RS10000	COG1414	Transcriptional regulator
EAKF1_RS10010	COG2224	Isocitrate lyase
EAKF1_RS10015	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EAKF1_RS10025	COG0456	acetyltransferase
EAKF1_RS10060	COG0151	Belongs to the GarS family
EAKF1_RS10065	COG2204	response regulator
EAKF1_RS10070	COG4191	Histidine kinase
EAKF1_RS10075	COG3678	ATP-independent chaperone mediated protein folding
EAKF1_RS10090	COG3068	Protein conserved in bacteria
EAKF1_RS10125	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EAKF1_RS10130	COG2104	thiamine diphosphate biosynthetic process
EAKF1_RS10140	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EAKF1_RS10185	COG0250	Participates in transcription elongation, termination and antitermination
EAKF1_RS10190	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EAKF1_RS10230	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EAKF1_RS10230	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EAKF1_RS10235	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EAKF1_RS10270	COG4206	TonB-dependent receptor
EAKF1_RS10290	COG0477	Major facilitator Superfamily
EAKF1_RS10295	COG1473	amidohydrolase
EAKF1_RS10305	COG0583	DNA-binding transcription factor activity
EAKF1_RS10320	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EAKF1_RS10335	COG2194	sulfuric ester hydrolase activity
EAKF1_RS10340	COG2207	Transcriptional regulator
EAKF1_RS10345	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EAKF1_RS10350	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EAKF1_RS10355	COG1882	Formate acetyltransferase
EAKF1_RS10360	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EAKF1_RS10365	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EAKF1_RS10370	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAKF1_RS10370	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAKF1_RS10370	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EAKF1_RS10375	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EAKF1_RS10380	COG0371	Dehydrogenase
EAKF1_RS10385	COG3738	Protein conserved in bacteria
EAKF1_RS10390	COG0697	spore germination
EAKF1_RS10400	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EAKF1_RS10410	COG0460	homoserine dehydrogenase
EAKF1_RS10410	COG0527	aspartate kinase activity
EAKF1_RS10415	COG0626	cystathionine gamma-synthase activity
EAKF1_RS10425	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
EAKF1_RS10435	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EAKF1_RS10440	COG1609	Transcriptional regulator
EAKF1_RS10445	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EAKF1_RS10460	COG1575	Belongs to the MenA family. Type 1 subfamily
EAKF1_RS10480	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EAKF1_RS10490	COG1494	fructose-1,6-bisphosphatase
EAKF1_RS10500	COG0589	response to stress
EAKF1_RS10505	COG3691	Protein conserved in bacteria
EAKF1_RS10510	COG3152	Membrane
EAKF1_RS10525	COG0477	Major facilitator Superfamily
EAKF1_RS10530	COG3829	transcription factor binding
EAKF1_RS10535	COG4948	Mandelate Racemase Muconate Lactonizing
EAKF1_RS10540	COG2223	nitrite transmembrane transporter activity
EAKF1_RS10550	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EAKF1_RS10615	COG5301	cellulose 1,4-beta-cellobiosidase activity
EAKF1_RS10675	COG4695	Portal protein
EAKF1_RS10745	COG4974	Belongs to the 'phage' integrase family
EAKF1_RS10750	COG3678	ATP-independent chaperone mediated protein folding
EAKF1_RS10755	COG0745	RESPONSE REGULATOR receiver
EAKF1_RS10760	COG2205	protein histidine kinase activity
EAKF1_RS10770	COG2258	MOSC domain
EAKF1_RS10775	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EAKF1_RS10790	COG3383	formate dehydrogenase (NAD+) activity
EAKF1_RS10790	COG0243	molybdopterin cofactor binding
EAKF1_RS10795	COG3383	formate dehydrogenase (NAD+) activity
EAKF1_RS10795	COG0243	molybdopterin cofactor binding
EAKF1_RS10800	COG0437	4 iron, 4 sulfur cluster binding
EAKF1_RS10805	COG2864	formate dehydrogenase
EAKF1_RS10835	COG0456	acetyltransferase
EAKF1_RS10850	COG1011	Hydrolase
EAKF1_RS10855	COG1349	DNA-binding transcription factor activity
EAKF1_RS10860	COG4372	Transposase
EAKF1_RS10865	COG3436	PFAM IS66 Orf2 family protein
EAKF1_RS10875	COG4372	Transposase
EAKF1_RS10890	COG4372	Transposase
EAKF1_RS10895	COG3436	PFAM IS66 Orf2 family protein
EAKF1_RS10930	COG1217	gtp-binding protein TYPA
EAKF1_RS10940	COG0174	glutamine synthetase
EAKF1_RS10945	COG3852	Histidine kinase
EAKF1_RS10950	COG2204	response regulator
EAKF1_RS10960	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EAKF1_RS10975	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EAKF1_RS10975	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EAKF1_RS10985	COG0204	Acyl-transferase
EAKF1_RS10995	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EAKF1_RS11000	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EAKF1_RS11005	COG3084	Protein conserved in bacteria
EAKF1_RS11010	COG0746	molybdenum cofactor guanylyltransferase activity
EAKF1_RS11015	COG1763	Mo-molybdopterin cofactor biosynthetic process
EAKF1_RS11040	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
EAKF1_RS11045	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EAKF1_RS11050	COG1739	Uncharacterized protein family UPF0029
EAKF1_RS11070	COG0543	2 iron, 2 sulfur cluster binding
EAKF1_RS11090	COG0805	protein transport
EAKF1_RS11100	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EAKF1_RS11110	COG3165	ubiquinone biosynthetic process from chorismate
EAKF1_RS11120	COG1322	Protein conserved in bacteria
EAKF1_RS11125	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
EAKF1_RS11130	COG0412	Dienelactone hydrolase
EAKF1_RS11140	COG0583	DNA-binding transcription factor activity
EAKF1_RS11145	COG0697	spore germination
EAKF1_RS11150	COG0561	phosphatase activity
EAKF1_RS11155	COG2267	carboxylic ester hydrolase activity
EAKF1_RS11160	COG1280	lysine exporter protein (LysE YggA)
EAKF1_RS11165	COG0514	ATP-dependent DNA helicase (RecQ)
EAKF1_RS11170	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
EAKF1_RS11175	COG2050	protein possibly involved in aromatic compounds catabolism
EAKF1_RS11180	COG2962	Rard protein
EAKF1_RS11195	COG0598	Magnesium transport protein CorA
EAKF1_RS11205	COG3698	Phosphodiester glycosidase
EAKF1_RS11210	COG0210	DNA helicase
EAKF1_RS11215	COG1011	Hydrolase
EAKF1_RS11225	COG3159	Protein conserved in bacteria
EAKF1_RS11235	COG5567	small periplasmic lipoprotein
EAKF1_RS11250	COG3072	Adenylate cyclase
EAKF1_RS11260	COG1587	Uroporphyrinogen-III synthase
EAKF1_RS11265	COG2959	enzyme of heme biosynthesis
EAKF1_RS11270	COG3071	HemY protein
EAKF1_RS11275	COG3119	arylsulfatase activity
EAKF1_RS11280	COG0641	radical SAM
EAKF1_RS11305	COG1113	amino acid transport
EAKF1_RS11325	COG2244	polysaccharide biosynthetic process
EAKF1_RS11330	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EAKF1_RS11335	COG0456	acetyltransferase
EAKF1_RS11340	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EAKF1_RS11345	COG1088	dTDP-glucose 4,6-dehydratase activity
EAKF1_RS11350	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EAKF1_RS11355	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EAKF1_RS11360	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
EAKF1_RS11365	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EAKF1_RS11375	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EAKF1_RS11385	COG3118	belongs to the thioredoxin family
EAKF1_RS11400	COG0210	DNA helicase
EAKF1_RS11405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EAKF1_RS11415	COG0583	DNA-binding transcription factor activity
EAKF1_RS11445	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EAKF1_RS11455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EAKF1_RS11460	COG3978	acetolactate synthase activity
EAKF1_RS11475	COG0606	chelatase, subunit chli
EAKF1_RS11480	COG3085	chromosome segregation
EAKF1_RS11520	COG2186	Transcriptional regulator
EAKF1_RS11525	COG0477	Major facilitator Superfamily
EAKF1_RS11530	COG1609	Transcriptional regulator
EAKF1_RS11535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EAKF1_RS11540	COG1879	ABC-type sugar transport system periplasmic component
EAKF1_RS11545	COG1172	Belongs to the binding-protein-dependent transport system permease family
EAKF1_RS11550	COG1129	ABC transporter
EAKF1_RS11580	COG1522	sequence-specific DNA binding
EAKF1_RS11585	COG0716	FMN binding
EAKF1_RS11600	COG3312	ion transport
EAKF1_RS11615	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EAKF1_RS11660	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EAKF1_RS11665	COG0573	inorganic phosphate transmembrane transporter activity
EAKF1_RS11670	COG0581	inorganic phosphate transmembrane transporter activity
EAKF1_RS11675	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EAKF1_RS11680	COG0704	Plays a role in the regulation of phosphate uptake
EAKF1_RS11685	COG3196	Protein conserved in bacteria
EAKF1_RS11690	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EAKF1_RS11695	COG2252	PERMEase
EAKF1_RS11710	COG3976	FMN-binding domain protein
EAKF1_RS11710	COG1053	succinate dehydrogenase
EAKF1_RS11725	COG2204	response regulator
EAKF1_RS11730	COG0431	NADPH-dependent FMN reductase
EAKF1_RS11735	COG2091	lysine biosynthetic process via aminoadipic acid
EAKF1_RS11750	COG0814	amino acid
EAKF1_RS11795	COG0592	DNA-directed DNA polymerase activity
EAKF1_RS11805	COG0187	DNA topoisomerase II activity
EAKF1_RS11815	COG3753	Protein conserved in bacteria
EAKF1_RS11820	COG0561	phosphatase activity
EAKF1_RS11835	COG0823	Involved in the tonB-independent uptake of proteins
EAKF1_RS11840	COG4372	Transposase
EAKF1_RS11845	COG3436	PFAM IS66 Orf2 family protein
EAKF1_RS11855	COG0823	Involved in the tonB-independent uptake of proteins
EAKF1_RS11860	COG5645	(Lipo)protein
EAKF1_RS11885	COG2188	Transcriptional regulator
EAKF1_RS11905	COG2149	membrane
EAKF1_RS11915	COG0641	radical SAM
EAKF1_RS11920	COG2814	Major facilitator Superfamily
EAKF1_RS11930	COG0028	Belongs to the TPP enzyme family
EAKF1_RS11935	COG0440	acetolactate synthase activity
EAKF1_RS11940	COG2197	response regulator
EAKF1_RS11945	COG3851	Histidine kinase
EAKF1_RS11950	COG2271	Major facilitator Superfamily
EAKF1_RS11955	COG2271	Major facilitator Superfamily
EAKF1_RS11965	COG2252	PERMEase
EAKF1_RS12015	COG0457	Tetratricopeptide repeat
EAKF1_RS12020	COG4372	Transposase
EAKF1_RS12025	COG3436	PFAM IS66 Orf2 family protein
EAKF1_RS12040	COG0697	spore germination
EAKF1_RS12045	COG2814	Major facilitator Superfamily
EAKF1_RS12060	COG0582	viral genome integration into host DNA
EAKF1_RS12070	COG2982	Protein involved in outer membrane biogenesis
EAKF1_RS12075	COG2233	PERMEase
EAKF1_RS12080	COG0786	glutamate:sodium symporter activity
EAKF1_RS12085	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EAKF1_RS12090	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EAKF1_RS12095	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EAKF1_RS12105	COG0194	GDP metabolic process
EAKF1_RS12115	COG2860	membrane
EAKF1_RS12120	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EAKF1_RS12125	COG3104	oligopeptide transport
EAKF1_RS12130	COG1982	Orn Lys Arg decarboxylase major
EAKF1_RS12135	COG0531	amino acid
EAKF1_RS12140	COG3710	Transcriptional regulator
EAKF1_RS12145	COG1561	YicC-like family, N-terminal region
EAKF1_RS12170	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EAKF1_RS12200	COG1519	Transferase
EAKF1_RS12205	COG0859	PFAM glycosyl transferase family 9
EAKF1_RS12210	COG0438	transferase activity, transferring glycosyl groups
EAKF1_RS12215	COG0515	serine threonine protein kinase
EAKF1_RS12220	COG0859	PFAM glycosyl transferase family 9
EAKF1_RS12225	COG0438	transferase activity, transferring glycosyl groups
EAKF1_RS12230	COG1442	glycosyl transferase family 8
EAKF1_RS12235	COG1442	glycosyl transferase family 8
EAKF1_RS12240	COG3642	lipopolysaccharide core region biosynthetic process
EAKF1_RS12260	COG0859	PFAM glycosyl transferase family 9
EAKF1_RS12265	COG0859	PFAM glycosyl transferase family 9
EAKF1_RS12275	COG0156	8-amino-7-oxononanoate synthase activity
EAKF1_RS12290	COG1216	Glycosyl transferase, family 2
EAKF1_RS12295	COG2861	carbohydrate metabolic process
EAKF1_RS12300	COG4942	peptidase
EAKF1_RS12310	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EAKF1_RS12315	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EAKF1_RS12330	COG1045	serine acetyltransferase
EAKF1_RS12335	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EAKF1_RS12345	COG2186	Transcriptional regulator
EAKF1_RS12350	COG1620	l-lactate permease
EAKF1_RS12355	COG5295	Hep Hag repeat protein
EAKF1_RS12375	COG3722	fumarate hydratase activity
EAKF1_RS12385	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAKF1_RS12385	COG2213	PTS system mannitol-specific
EAKF1_RS12395	COG1566	PFAM secretion protein HlyD family protein
EAKF1_RS12400	COG2258	MOSC domain
EAKF1_RS12405	COG0625	glutathione transferase activity
EAKF1_RS12415	COG3276	selenocysteine insertion sequence binding
EAKF1_RS12420	COG1454	alcohol dehydrogenase
EAKF1_RS12430	COG1012	belongs to the aldehyde dehydrogenase family
EAKF1_RS12450	COG1598	PFAM Uncharacterised protein family UPF0150
EAKF1_RS12460	COG2211	Major facilitator Superfamily
EAKF1_RS12470	COG0235	Class ii aldolase
EAKF1_RS12475	COG3623	hexulose-6-phosphate isomerase
EAKF1_RS12480	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
EAKF1_RS12485	COG1070	Carbohydrate kinase
EAKF1_RS12490	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EAKF1_RS12495	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EAKF1_RS12500	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EAKF1_RS12510	COG2731	YhcH YjgK YiaL family protein
EAKF1_RS12520	COG1414	Transcriptional regulator
EAKF1_RS12525	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EAKF1_RS12535	COG3977	Valine--pyruvate aminotransferase
EAKF1_RS12540	COG2992	FlgJ-related protein
EAKF1_RS12545	COG4682	membrane
EAKF1_RS12550	COG3274	enterobacterial common antigen metabolic process
EAKF1_RS12585	COG1278	Cold shock
EAKF1_RS12590	COG2944	sequence-specific DNA binding
EAKF1_RS12605	COG2885	chlorophyll binding
EAKF1_RS12615	COG0456	acetyltransferase
EAKF1_RS12620	COG2818	Glycosylase
EAKF1_RS12625	COG5571	outer membrane autotransporter
EAKF1_RS12630	COG2223	nitrite transmembrane transporter activity
EAKF1_RS12635	COG3539	Fimbrial protein
EAKF1_RS12640	COG3121	Chaperone
EAKF1_RS12650	COG3539	Fimbrial protein
EAKF1_RS12665	COG3539	Fimbrial protein
EAKF1_RS12670	COG2194	sulfuric ester hydrolase activity
EAKF1_RS12685	COG0747	negative chemotaxis
EAKF1_RS12695	COG0601	transmembrane transport
EAKF1_RS12700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EAKF1_RS12705	COG0444	Belongs to the ABC transporter superfamily
EAKF1_RS12710	COG4608	Belongs to the ABC transporter superfamily
EAKF1_RS12715	COG0814	amino acid
EAKF1_RS12750	COG2194	sulfuric ester hydrolase activity
EAKF1_RS12765	COG3118	belongs to the thioredoxin family
EAKF1_RS12765	COG0457	Tetratricopeptide repeat
EAKF1_RS12770	COG2199	diguanylate cyclase activity
EAKF1_RS12770	COG2200	EAL domain
EAKF1_RS12780	COG0612	Peptidase, M16
EAKF1_RS12785	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EAKF1_RS12795	COG2200	EAL domain
EAKF1_RS12800	COG0477	Major facilitator Superfamily
EAKF1_RS12805	COG1295	ribonuclease BN
EAKF1_RS12810	COG0583	DNA-binding transcription factor activity
EAKF1_RS12815	COG2197	response regulator
EAKF1_RS12825	COG1858	cytochrome C peroxidase
EAKF1_RS12830	COG0076	glutamate decarboxylase activity
EAKF1_RS12835	COG2207	Transcriptional regulator
EAKF1_RS12840	COG2207	Transcriptional regulator
EAKF1_RS12845	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EAKF1_RS12850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAKF1_RS12860	COG2771	luxR family
EAKF1_RS12865	COG3247	response to pH
EAKF1_RS12885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EAKF1_RS12895	COG3721	Heme iron utilization protein
EAKF1_RS12905	COG4558	Periplasmic binding protein
EAKF1_RS12920	COG3720	iron ion transport
EAKF1_RS12930	COG3065	identical protein binding
EAKF1_RS12935	COG3093	addiction module antidote protein HigA
EAKF1_RS12940	COG3549	Plasmid maintenance system killer
EAKF1_RS12960	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EAKF1_RS12965	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EAKF1_RS12970	COG0339	signal peptide processing
EAKF1_RS12980	COG3104	oligopeptide transport
EAKF1_RS12985	COG0589	response to stress
EAKF1_RS12995	COG0306	phosphate transporter
EAKF1_RS13000	COG2081	HI0933 family
EAKF1_RS13010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAKF1_RS13015	COG1129	ABC transporter
EAKF1_RS13015	COG0842	Transport permease protein
EAKF1_RS13020	COG0842	Transport permease protein
EAKF1_RS13040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EAKF1_RS13045	COG0601	transmembrane transport
EAKF1_RS13050	COG0747	negative chemotaxis
EAKF1_RS13055	COG2091	lysine biosynthetic process via aminoadipic acid
EAKF1_RS13060	COG0628	permease
EAKF1_RS13065	COG0477	Major facilitator Superfamily
EAKF1_RS13075	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EAKF1_RS13095	COG3714	YhhN family
EAKF1_RS13105	COG3776	membrane
EAKF1_RS13110	COG0742	ribosomal rna small subunit methyltransferase
EAKF1_RS13115	COG0552	protein localization to endoplasmic reticulum
EAKF1_RS13120	COG2884	Cell division ATP-binding protein ftsE
EAKF1_RS13125	COG2177	Part of the ABC transporter FtsEX involved in
EAKF1_RS13130	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EAKF1_RS13135	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EAKF1_RS13165	COG0683	leucine binding
EAKF1_RS13170	COG0456	acetyltransferase
EAKF1_RS13175	COG0683	leucine binding
EAKF1_RS13180	COG0559	Belongs to the binding-protein-dependent transport system permease family
EAKF1_RS13185	COG4177	L-phenylalanine transmembrane transporter activity
EAKF1_RS13190	COG0411	ABC transporter
EAKF1_RS13195	COG0410	ABC transporter
EAKF1_RS13215	COG1175	transmembrane transport
EAKF1_RS13230	COG0584	glycerophosphoryl diester phosphodiesterase
EAKF1_RS13240	COG0405	Gamma-glutamyltransferase
EAKF1_RS13245	COG1247	-acetyltransferase
EAKF1_RS13255	COG0673	inositol 2-dehydrogenase activity
EAKF1_RS13260	COG1741	Belongs to the pirin family
EAKF1_RS13265	COG1609	Transcriptional regulator
EAKF1_RS13270	COG3265	gluconokinase activity
EAKF1_RS13275	COG2610	gluconate transmembrane transporter activity
EAKF1_RS13280	COG2095	MarC family integral membrane protein
EAKF1_RS13285	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EAKF1_RS13310	COG0058	SHG alpha-glucan phosphorylase activity
EAKF1_RS13315	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EAKF1_RS13350	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EAKF1_RS13365	COG1349	DNA-binding transcription factor activity
EAKF1_RS13370	COG4650	regulator
EAKF1_RS13375	COG1690	Belongs to the RtcB family
EAKF1_RS13390	COG0058	SHG alpha-glucan phosphorylase activity
EAKF1_RS13395	COG1640	4-alpha-glucanotransferase
EAKF1_RS13400	COG2610	gluconate transmembrane transporter activity
EAKF1_RS13420	COG5464	transposase or invertase
EAKF1_RS13430	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EAKF1_RS13435	COG1918	ferrous iron import across plasma membrane
EAKF1_RS13440	COG2183	response to ionizing radiation
EAKF1_RS13445	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EAKF1_RS13485	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EAKF1_RS13490	COG1011	Hydrolase
EAKF1_RS13500	COG0494	nUDIX hydrolase
EAKF1_RS13510	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EAKF1_RS13515	COG4972	Pilus assembly protein
EAKF1_RS13520	COG3166	PFAM Fimbrial assembly family protein
EAKF1_RS13535	COG4796	Type ii and iii secretion system protein
EAKF1_RS13550	COG3266	domain, Protein
EAKF1_RS13555	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EAKF1_RS13560	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EAKF1_RS13570	COG0180	Tryptophanyl-tRNA synthetase
EAKF1_RS13575	COG2188	Transcriptional regulator
EAKF1_RS13585	COG3457	Alanine racemase
EAKF1_RS13590	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EAKF1_RS13595	COG1735	metal-dependent hydrolase with the TIM-barrel fold
EAKF1_RS13610	COG0626	cystathionine gamma-synthase activity
EAKF1_RS13625	COG2116	formate transmembrane transporter activity
EAKF1_RS13630	COG2146	nitrite reductase [NAD(P)H] activity
EAKF1_RS13635	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EAKF1_RS13645	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EAKF1_RS13655	COG2184	nucleotidyltransferase activity
EAKF1_RS13660	COG0512	Glutamine amidotransferase of anthranilate synthase
EAKF1_RS13665	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EAKF1_RS13670	COG1289	transmembrane transporter activity
EAKF1_RS13675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EAKF1_RS13685	COG1765	OsmC-like protein
EAKF1_RS13690	COG3954	Phosphoribulokinase
EAKF1_RS13700	COG0429	hydrolase of the alpha beta-hydrolase fold
EAKF1_RS13705	COG0488	(ABC) transporter
EAKF1_RS13720	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
EAKF1_RS13725	COG1047	Peptidyl-prolyl cis-trans
EAKF1_RS13735	COG0545	Peptidyl-prolyl cis-trans isomerase
EAKF1_RS13740	COG2964	Protein conserved in bacteria
EAKF1_RS13815	COG0089	rRNA binding
EAKF1_RS13905	COG0201	protein transport
EAKF1_RS13945	COG0789	Transcriptional regulator
EAKF1_RS13950	COG3036	rescue of stalled ribosome
EAKF1_RS13960	COG0569	domain protein
EAKF1_RS13980	COG0758	DNA mediated transformation
EAKF1_RS13990	COG0551	DNA topoisomerase type I activity
EAKF1_RS14010	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EAKF1_RS14065	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EAKF1_RS14070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAKF1_RS14075	COG1309	transcriptional regulator
EAKF1_RS14080	COG2189	Belongs to the N(4) N(6)-methyltransferase family
EAKF1_RS14090	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EAKF1_RS14100	COG4145	pantothenate transmembrane transporter activity
EAKF1_RS14105	COG3924	membrane
EAKF1_RS14110	COG0439	Biotin carboxylase
EAKF1_RS14115	COG0511	ligase activity, forming carbon-carbon bonds
EAKF1_RS14135	COG0604	alcohol dehydrogenase
EAKF1_RS14140	COG2200	EAL domain
EAKF1_RS14140	COG2199	diguanylate cyclase activity
EAKF1_RS14150	COG1077	Cell shape determining protein MreB Mrl
EAKF1_RS14155	COG1792	Involved in formation and maintenance of cell shape
EAKF1_RS14160	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EAKF1_RS14170	COG1530	ribonuclease E activity
EAKF1_RS14175	COG3164	Protein of unknown function
EAKF1_RS14180	COG0312	modulator of DNA gyrase
EAKF1_RS14185	COG0471	metal ion transport
EAKF1_RS14205	COG0583	DNA-binding transcription factor activity
EAKF1_RS14225	COG2732	(Barnase) inhibitor
EAKF1_RS14245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EAKF1_RS14250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EAKF1_RS14255	COG3105	Protein conserved in bacteria
EAKF1_RS14260	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EAKF1_RS14275	COG0625	glutathione transferase activity
EAKF1_RS14280	COG2969	positive regulation of protein catabolic process
EAKF1_RS14310	COG2731	YhcH YjgK YiaL family protein
EAKF1_RS14315	COG4804	nuclease activity
EAKF1_RS14320	COG0493	'glutamate synthase
EAKF1_RS14325	COG0069	glutamate synthase activity
EAKF1_RS14325	COG0070	glutamate synthase
EAKF1_RS14325	COG0067	glutamate synthase
EAKF1_RS14330	COG1242	4 iron, 4 sulfur cluster binding
EAKF1_RS14335	COG0784	Response regulator, receiver
EAKF1_RS14335	COG2198	Histidine kinase
EAKF1_RS14335	COG5002	protein histidine kinase activity
EAKF1_RS14340	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
EAKF1_RS14350	COG0515	serine threonine protein kinase
EAKF1_RS14355	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAKF1_RS14370	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EAKF1_RS14375	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EAKF1_RS14380	COG1137	ATPase activity
EAKF1_RS14385	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EAKF1_RS14390	COG3117	lipopolysaccharide transmembrane transporter activity
EAKF1_RS14395	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EAKF1_RS14400	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EAKF1_RS14400	COG0517	IMP dehydrogenase activity
EAKF1_RS14405	COG0530	calcium, potassium:sodium antiporter activity
EAKF1_RS14410	COG1127	ABC transporter
EAKF1_RS14415	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EAKF1_RS14420	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EAKF1_RS14425	COG2854	intermembrane phospholipid transfer
EAKF1_RS14430	COG3113	response to antibiotic
EAKF1_RS14435	COG5007	Belongs to the BolA IbaG family
EAKF1_RS14445	COG3423	Transcriptional regulator
EAKF1_RS14450	COG0142	geranyltranstransferase activity
EAKF1_RS14465	COG0697	spore germination
EAKF1_RS14475	COG2027	D-alanyl-D-alanine carboxypeptidase
EAKF1_RS14480	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EAKF1_RS14485	COG1534	Rna-binding protein
EAKF1_RS14495	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EAKF1_RS14500	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EAKF1_RS14510	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EAKF1_RS14535	COG0195	Participates in both transcription termination and antitermination
EAKF1_RS14570	COG0513	Belongs to the DEAD box helicase family
EAKF1_RS14580	COG0814	amino acid
EAKF1_RS14590	COG3034	peptidoglycan biosynthetic process
EAKF1_RS14595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EAKF1_RS14600	COG0826	peptidase U32
EAKF1_RS14605	COG0826	peptidase U32
EAKF1_RS14610	COG3154	lipid carrier protein
EAKF1_RS14615	COG3153	acetyltransferase
EAKF1_RS14630	COG0702	epimerase
EAKF1_RS14635	COG2823	Periplasmic or secreted lipoprotein
EAKF1_RS14650	COG3107	peptidoglycan biosynthetic process
EAKF1_RS14655	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EAKF1_RS14660	COG0363	glucosamine-6-phosphate deaminase activity
EAKF1_RS14665	COG3716	PTS system mannose fructose sorbose family IID component
EAKF1_RS14670	COG3715	PTS system
EAKF1_RS14675	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EAKF1_RS14685	COG2222	sugar isomerase
EAKF1_RS14700	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EAKF1_RS14705	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAKF1_RS14710	COG3716	PTS system mannose fructose sorbose family IID component
EAKF1_RS14720	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EAKF1_RS14730	COG1349	DNA-binding transcription factor activity
EAKF1_RS14735	COG2721	sulfolactate sulfo-lyase activity
EAKF1_RS14740	COG2271	Major facilitator Superfamily
EAKF1_RS14750	COG2084	Dehydrogenase
EAKF1_RS14755	COG1929	Belongs to the glycerate kinase type-1 family
EAKF1_RS14765	COG0583	DNA-binding transcription factor activity
EAKF1_RS14770	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EAKF1_RS14780	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EAKF1_RS14785	COG1882	Formate acetyltransferase
EAKF1_RS14790	COG0251	oxidation-reduction process
EAKF1_RS14795	COG1760	l-serine dehydratase
EAKF1_RS14800	COG0814	amino acid
EAKF1_RS14815	COG1741	Belongs to the pirin family
EAKF1_RS14820	COG0583	DNA-binding transcription factor activity
EAKF1_RS14825	COG3152	Membrane
EAKF1_RS14830	COG0435	Glutathione S-transferase
EAKF1_RS14840	COG2259	Doxx family
EAKF1_RS14850	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
EAKF1_RS14855	COG4575	ribosome binding
EAKF1_RS14860	COG1422	Protein of unknown function (DUF1090)
EAKF1_RS14870	COG0586	Pfam SNARE associated Golgi protein
EAKF1_RS14875	COG2186	Transcriptional regulator
EAKF1_RS14880	COG2271	Major facilitator Superfamily
EAKF1_RS14890	COG2721	sulfolactate sulfo-lyase activity
EAKF1_RS14900	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
EAKF1_RS14905	COG0861	Integral membrane protein TerC family
EAKF1_RS14910	COG0673	inositol 2-dehydrogenase activity
EAKF1_RS14915	COG2949	membrane
EAKF1_RS14920	COG1451	nucleotide metabolic process
EAKF1_RS14935	COG5499	transcription regulator containing HTH domain
EAKF1_RS14940	COG0446	pyridine nucleotide-disulphide oxidoreductase
EAKF1_RS14940	COG1902	pentaerythritol trinitrate reductase activity
EAKF1_RS14945	COG3408	Glycogen debranching enzyme
EAKF1_RS14945	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
EAKF1_RS14955	COG0531	amino acid
EAKF1_RS14960	COG2731	YhcH YjgK YiaL family protein
EAKF1_RS14965	COG3250	beta-galactosidase activity
EAKF1_RS14970	COG1609	Transcriptional regulator
EAKF1_RS14975	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EAKF1_RS14985	COG1695	Transcriptional regulator
EAKF1_RS14990	COG2375	cellular response to nickel ion
EAKF1_RS15005	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EAKF1_RS15010	COG0358	DNA primase activity
EAKF1_RS15015	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EAKF1_RS15025	COG0471	metal ion transport
EAKF1_RS15030	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EAKF1_RS15050	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EAKF1_RS15065	COG4991	sh3 domain protein
EAKF1_RS15075	COG3025	triphosphatase activity
EAKF1_RS15105	COG2268	Band 7 protein
EAKF1_RS15110	COG1585	Membrane protein implicated in regulation of membrane protease activity
EAKF1_RS15120	COG2960	long-chain fatty acid transporting porin activity
EAKF1_RS15150	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EAKF1_RS15160	COG0754	glutathionylspermidine amidase activity
EAKF1_RS15175	COG1538	Outer membrane efflux protein
EAKF1_RS15180	COG0494	nUDIX hydrolase
EAKF1_RS15185	COG3151	Protein conserved in bacteria
EAKF1_RS15190	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EAKF1_RS15195	COG3150	esterase
EAKF1_RS15200	COG0187	DNA topoisomerase II activity
EAKF1_RS15205	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EAKF1_RS15210	COG2249	NAD(P)H dehydrogenase (quinone) activity
EAKF1_RS15215	COG0642	Histidine kinase
EAKF1_RS15220	COG0745	RESPONSE REGULATOR receiver
EAKF1_RS15225	COG3111	PFAM Bacterial OB fold (BOF) protein
EAKF1_RS15230	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
EAKF1_RS15235	COG4166	transmembrane transport
EAKF1_RS15240	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EAKF1_RS15245	COG0204	Acyl-transferase
EAKF1_RS15250	COG2132	Multicopper oxidase
EAKF1_RS15285	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EAKF1_RS15295	COG0246	Mannitol dehydrogenase
EAKF1_RS15300	COG2186	Transcriptional regulator
EAKF1_RS15305	COG1032	radical SAM domain protein
EAKF1_RS15310	COG4238	major outer membrane lipoprotein
EAKF1_RS15330	COG0471	metal ion transport
EAKF1_RS15335	COG0656	L-ascorbic acid biosynthetic process
EAKF1_RS15340	COG1979	alcohol dehydrogenase
EAKF1_RS15350	COG2207	Transcriptional regulator
EAKF1_RS15355	COG0586	Pfam SNARE associated Golgi protein
EAKF1_RS15360	COG0626	cystathionine gamma-synthase activity
EAKF1_RS15370	COG0811	peptide transport
EAKF1_RS15375	COG0848	biopolymer transport protein
EAKF1_RS15380	COG0667	Aldo Keto reductase
EAKF1_RS15390	COG4977	sequence-specific DNA binding
EAKF1_RS15395	COG0318	PFAM AMP-dependent synthetase and ligase
EAKF1_RS15405	COG1924	4 iron, 4 sulfur cluster binding
EAKF1_RS15435	COG2610	gluconate transmembrane transporter activity
EAKF1_RS15445	COG2086	electron transfer activity
EAKF1_RS15450	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EAKF1_RS15455	COG0644	oxidoreductase
EAKF1_RS15460	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
EAKF1_RS15470	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
EAKF1_RS15475	COG0437	4 iron, 4 sulfur cluster binding
EAKF1_RS15480	COG5557	Pfam Polysulphide reductase, NrfD
EAKF1_RS15485	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
EAKF1_RS15490	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EAKF1_RS15495	COG1773	rubredoxin
EAKF1_RS15505	COG0298	carbon dioxide binding
EAKF1_RS15510	COG0625	glutathione transferase activity
EAKF1_RS15515	COG0754	glutathionylspermidine amidase activity
EAKF1_RS15520	COG0306	phosphate transporter
EAKF1_RS15525	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EAKF1_RS15530	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EAKF1_RS15535	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EAKF1_RS15540	COG2244	polysaccharide biosynthetic process
EAKF1_RS15550	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
EAKF1_RS15555	COG0795	lipopolysaccharide-transporting ATPase activity
EAKF1_RS15565	COG0156	8-amino-7-oxononanoate synthase activity
EAKF1_RS15570	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EAKF1_RS15580	COG0318	PFAM AMP-dependent synthetase and ligase
EAKF1_RS15585	COG0456	acetyltransferase
EAKF1_RS15595	COG0277	FAD linked oxidase domain protein
EAKF1_RS15600	COG0277	FAD linked oxidase domain protein
EAKF1_RS15605	COG0247	lactate metabolic process
EAKF1_RS15610	COG3193	protein, possibly involved in utilization of glycolate and propanediol
EAKF1_RS15615	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EAKF1_RS15620	COG1620	l-lactate permease
EAKF1_RS15630	COG3064	Membrane
EAKF1_RS15635	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EAKF1_RS15655	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EAKF1_RS15660	COG1459	type II secretion system
EAKF1_RS15665	COG2165	general secretion pathway protein
EAKF1_RS15695	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
EAKF1_RS15700	COG0583	DNA-binding transcription factor activity
EAKF1_RS15710	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EAKF1_RS15765	COG3436	PFAM IS66 Orf2 family protein
EAKF1_RS15770	COG4372	Transposase
EAKF1_RS15785	COG2801	Transposase and inactivated derivatives
EAKF1_RS15795	COG0582	viral genome integration into host DNA
EAKF1_RS15805	COG1811	Na channel or pump
EAKF1_RS15815	COG1982	Orn Lys Arg decarboxylase major
EAKF1_RS15830	COG1982	Orn Lys Arg decarboxylase major
EAKF1_RS15835	COG2211	Major facilitator Superfamily
EAKF1_RS15850	COG1194	a g-specific adenine glycosylase
EAKF1_RS15860	COG3171	Protein conserved in bacteria
EAKF1_RS15875	COG0252	asparaginase activity
EAKF1_RS15885	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EAKF1_RS15900	COG0762	integral membrane protein
EAKF1_RS15905	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EAKF1_RS15910	COG2805	Type II/IV secretion system protein
EAKF1_RS15925	COG0189	ligase activity
EAKF1_RS15930	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EAKF1_RS15935	COG2356	endonuclease I
EAKF1_RS15945	COG2814	Major facilitator Superfamily
EAKF1_RS15970	COG1166	arginine decarboxylase activity
EAKF1_RS15990	COG0501	Belongs to the peptidase M48B family
EAKF1_RS15995	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EAKF1_RS16000	COG0330	HflC and HflK could
EAKF1_RS16005	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAKF1_RS16010	COG2213	PTS system mannitol-specific
EAKF1_RS16015	COG1063	alcohol dehydrogenase
EAKF1_RS16020	COG1494	fructose-1,6-bisphosphatase
EAKF1_RS16030	COG1072	(Pantothenic acid kinase))
EAKF1_RS16045	COG0191	fructose-bisphosphate aldolase activity
EAKF1_RS16050	COG0668	transmembrane transport
EAKF1_RS16060	COG1279	arginine transmembrane transporter activity
EAKF1_RS16065	COG2968	Membrane
EAKF1_RS16070	COG0583	DNA-binding transcription factor activity
EAKF1_RS16075	COG0427	acetyl-CoA hydrolase
EAKF1_RS16080	COG1024	Enoyl-CoA hydratase
EAKF1_RS16085	COG1703	isobutyryl-CoA mutase activity
EAKF1_RS16090	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EAKF1_RS16090	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EAKF1_RS16105	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EAKF1_RS16115	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EAKF1_RS16130	COG0006	proline dipeptidase activity
EAKF1_RS16135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EAKF1_RS16140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EAKF1_RS16165	COG2723	6-phospho-beta-galactosidase activity
EAKF1_RS16175	COG1272	protein, Hemolysin III
EAKF1_RS16190	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EAKF1_RS16200	COG0716	FMN binding
EAKF1_RS16205	COG4974	Belongs to the 'phage' integrase family
EAKF1_RS16210	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EAKF1_RS16215	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EAKF1_RS16225	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EAKF1_RS16230	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EAKF1_RS16245	COG3436	PFAM IS66 Orf2 family protein
EAKF1_RS16250	COG4372	Transposase
EAKF1_RS16255	COG2233	PERMEase
EAKF1_RS16265	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EAKF1_RS16265	COG0493	'glutamate synthase
EAKF1_RS16270	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EAKF1_RS16285	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EAKF1_RS16290	COG2252	PERMEase
EAKF1_RS16295	COG0402	S-adenosylhomocysteine deaminase activity
EAKF1_RS16300	COG2233	PERMEase
EAKF1_RS16305	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EAKF1_RS16305	COG2080	2 iron, 2 sulfur cluster binding
EAKF1_RS16310	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EAKF1_RS16315	COG0402	S-adenosylhomocysteine deaminase activity
EAKF1_RS16320	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EAKF1_RS16320	COG0493	'glutamate synthase
EAKF1_RS16325	COG2068	MobA-Related Protein
EAKF1_RS16330	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EAKF1_RS16335	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EAKF1_RS16335	COG3608	succinylglutamate desuccinylase aspartoacylase
EAKF1_RS16340	COG0549	Belongs to the carbamate kinase family
EAKF1_RS16350	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EAKF1_RS16355	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EAKF1_RS16360	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EAKF1_RS16365	COG3829	transcription factor binding
EAKF1_RS16370	COG2080	2 iron, 2 sulfur cluster binding
EAKF1_RS16375	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EAKF1_RS16390	COG3436	PFAM IS66 Orf2 family protein
EAKF1_RS16395	COG4372	Transposase
EAKF1_RS16400	COG4942	peptidase
EAKF1_RS16410	COG3387	PFAM Glycoside hydrolase 15-related
EAKF1_RS16420	COG2207	Transcriptional regulator
EAKF1_RS16540	COG2197	response regulator
EAKF1_RS16545	COG0741	lytic transglycosylase activity
EAKF1_RS16555	COG0457	Tetratricopeptide repeat
EAKF1_RS16555	COG3710	Transcriptional regulator
EAKF1_RS16580	COG3710	Transcriptional regulator
EAKF1_RS16585	COG2771	luxR family
EAKF1_RS16590	COG0814	amino acid
EAKF1_RS16595	COG0183	Belongs to the thiolase family
EAKF1_RS16600	COG1794	racemase activity, acting on amino acids and derivatives
EAKF1_RS16605	COG0583	DNA-binding transcription factor activity
EAKF1_RS16615	COG1609	Transcriptional regulator
EAKF1_RS16630	COG0667	Aldo Keto reductase
EAKF1_RS16640	COG0861	Integral membrane protein TerC family
EAKF1_RS16665	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
EAKF1_RS16680	COG2165	general secretion pathway protein
EAKF1_RS16685	COG4795	General secretion pathway protein
EAKF1_RS16695	COG4967	type IV pilus modification protein PilV
EAKF1_RS16700	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EAKF1_RS16705	COG1025	Belongs to the peptidase M16 family
EAKF1_RS16710	COG1074	ATP-dependent DNA helicase activity
EAKF1_RS16715	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EAKF1_RS16720	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EAKF1_RS16720	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EAKF1_RS16725	COG0860	N-Acetylmuramoyl-L-alanine amidase
EAKF1_RS16745	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
EAKF1_RS16750	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EAKF1_RS16755	COG2166	iron-sulfur cluster assembly
EAKF1_RS16760	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EAKF1_RS16770	COG0583	DNA-binding transcription factor activity
EAKF1_RS16775	COG2363	Small membrane protein
EAKF1_RS16785	COG1349	DNA-binding transcription factor activity
EAKF1_RS16795	COG1070	Carbohydrate kinase
EAKF1_RS16805	COG0738	Major facilitator superfamily
EAKF1_RS16810	COG0235	Class ii aldolase
EAKF1_RS16815	COG1454	alcohol dehydrogenase
EAKF1_RS16825	COG1760	l-serine dehydratase
EAKF1_RS16830	COG0814	amino acid
EAKF1_RS16835	COG1611	Belongs to the LOG family
EAKF1_RS16855	COG3098	single-species biofilm formation
EAKF1_RS16860	COG0564	pseudouridine synthase activity
EAKF1_RS16865	COG0716	FMN binding
EAKF1_RS16870	COG2205	protein histidine kinase activity
EAKF1_RS16870	COG3850	Histidine kinase
EAKF1_RS16870	COG4999	Histidine kinase
EAKF1_RS16870	COG3437	response regulator, receiver
EAKF1_RS16875	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EAKF1_RS16880	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EAKF1_RS16885	COG3956	TIGRFAM MazG family protein
EAKF1_RS16905	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
EAKF1_RS16915	COG0602	queuosine metabolic process
EAKF1_RS16920	COG0644	oxidoreductase
EAKF1_RS16925	COG0720	synthase
EAKF1_RS16930	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EAKF1_RS16950	COG2234	aminopeptidase activity
EAKF1_RS16990	COG0585	pseudouridine synthase activity
EAKF1_RS17005	COG4942	peptidase
EAKF1_RS17005	COG1388	LysM domain
EAKF1_RS17010	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EAKF1_RS17020	COG0163	prenyltransferase activity
EAKF1_RS17025	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EAKF1_RS17035	COG2610	gluconate transmembrane transporter activity
EAKF1_RS17040	COG3622	Belongs to the hyi family
EAKF1_RS17045	COG0235	Class ii aldolase
EAKF1_RS17050	COG3395	kinase activity
EAKF1_RS17055	COG2084	Dehydrogenase
EAKF1_RS17060	COG1349	DNA-binding transcription factor activity
EAKF1_RS17065	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EAKF1_RS17085	COG3604	Transcriptional regulator
EAKF1_RS17090	COG0309	Hydrogenase expression formation protein (HypE)
EAKF1_RS17095	COG0409	Hydrogenase expression formation protein
EAKF1_RS17100	COG0298	carbon dioxide binding
EAKF1_RS17105	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EAKF1_RS17110	COG0375	protein maturation
EAKF1_RS17125	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EAKF1_RS17130	COG0651	ATP synthesis coupled electron transport
EAKF1_RS17135	COG0650	Formate hydrogenlyase subunit 4
EAKF1_RS17140	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
EAKF1_RS17140	COG3261	NADH dehydrogenase
EAKF1_RS17145	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EAKF1_RS17150	COG3260	NADH ubiquinone oxidoreductase 20
EAKF1_RS17160	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EAKF1_RS17170	COG4680	protein conserved in bacteria
EAKF1_RS17175	COG5499	transcription regulator containing HTH domain
EAKF1_RS17185	COG2723	6-phospho-beta-galactosidase activity
EAKF1_RS17190	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EAKF1_RS17195	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
EAKF1_RS17210	COG3604	Transcriptional regulator
EAKF1_RS17215	COG0517	IMP dehydrogenase activity
EAKF1_RS17215	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EAKF1_RS17220	COG2951	lytic endotransglycosylase activity
EAKF1_RS17230	COG1546	Belongs to the CinA family
EAKF1_RS17255	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EAKF1_RS17280	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EAKF1_RS17285	COG1238	metal cluster binding
EAKF1_RS17315	COG2814	Major facilitator Superfamily
EAKF1_RS17320	COG1566	PFAM secretion protein HlyD family protein
EAKF1_RS17325	COG1846	Transcriptional regulator
EAKF1_RS17335	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EAKF1_RS17340	COG2814	Major facilitator Superfamily
EAKF1_RS17345	COG2113	Glycine betaine
EAKF1_RS17350	COG4176	ABC-type proline glycine betaine transport system permease component
EAKF1_RS17355	COG4175	Glycine betaine
EAKF1_RS17360	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EAKF1_RS17365	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EAKF1_RS17375	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EAKF1_RS17380	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EAKF1_RS17390	COG4575	ribosome binding
EAKF1_RS17405	COG2916	Histone family protein nucleoid-structuring protein H-NS
EAKF1_RS17410	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EAKF1_RS17415	COG0640	Transcriptional regulator
EAKF1_RS17420	COG0401	homolog of Blt101
EAKF1_RS17425	COG1802	Transcriptional regulator
EAKF1_RS17430	COG1113	amino acid transport
EAKF1_RS17435	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EAKF1_RS17440	COG1012	belongs to the aldehyde dehydrogenase family
EAKF1_RS17445	COG0579	oxidoreductase
EAKF1_RS17505	COG3436	PFAM IS66 Orf2 family protein
EAKF1_RS17510	COG4372	Transposase
EAKF1_RS17525	COG3436	PFAM IS66 Orf2 family protein
EAKF1_RS17530	COG4372	Transposase
EAKF1_RS17535	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EAKF1_RS17540	COG0732	type I restriction modification DNA specificity domain
EAKF1_RS17545	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EAKF1_RS17555	COG1475	DNA binding
EAKF1_RS17565	COG0582	viral genome integration into host DNA
EAKF1_RS17590	COG0582	viral genome integration into host DNA
EAKF1_RS17600	COG4974	Belongs to the 'phage' integrase family
EAKF1_RS17635	COG2867	negative regulation of translational initiation
EAKF1_RS17645	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EAKF1_RS17650	COG0497	DNA recombination
EAKF1_RS17665	COG4536	flavin adenine dinucleotide binding
EAKF1_RS17670	COG4137	Cytochrome C assembly protein
EAKF1_RS17675	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EAKF1_RS17700	COG2885	chlorophyll binding
EAKF1_RS17705	COG2199	diguanylate cyclase activity
EAKF1_RS17720	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EAKF1_RS17725	COG1605	Chorismate mutase
EAKF1_RS17725	COG0287	Prephenate dehydrogenase
EAKF1_RS17730	COG1605	Chorismate mutase
EAKF1_RS17730	COG0077	Prephenate dehydratase
EAKF1_RS17735	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EAKF1_RS17745	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EAKF1_RS17750	COG0564	pseudouridine synthase activity
EAKF1_RS17760	COG0542	response to heat
EAKF1_RS17785	COG0477	Major facilitator Superfamily
EAKF1_RS17790	COG5544	Lipoprotein
EAKF1_RS17795	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EAKF1_RS17800	COG0045	succinate-CoA ligase (ADP-forming) activity
EAKF1_RS17800	COG1042	CoA-binding domain protein
EAKF1_RS17800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EAKF1_RS17810	COG3118	belongs to the thioredoxin family
EAKF1_RS17820	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EAKF1_RS17845	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EAKF1_RS17850	COG2086	electron transfer activity
EAKF1_RS17865	COG2271	Major facilitator Superfamily
EAKF1_RS17895	COG0583	DNA-binding transcription factor activity
EAKF1_RS17900	COG0513	Belongs to the DEAD box helicase family
EAKF1_RS17910	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EAKF1_RS17920	COG1595	DNA-templated transcription, initiation
EAKF1_RS17925	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
EAKF1_RS17930	COG3026	antisigma factor binding
EAKF1_RS17935	COG3086	response to oxidative stress
EAKF1_RS17945	COG0681	Belongs to the peptidase S26 family
EAKF1_RS17965	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EAKF1_RS17990	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EAKF1_RS17995	COG1737	Transcriptional regulator
EAKF1_RS18000	COG0560	Phosphoserine phosphatase
EAKF1_RS18015	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EAKF1_RS18015	COG0047	phosphoribosylformylglycinamidine synthase activity
EAKF1_RS18025	COG2205	protein histidine kinase activity
EAKF1_RS18030	COG3170	Tfp pilus assembly protein FimV
EAKF1_RS18035	COG2204	response regulator
EAKF1_RS18040	COG0347	Belongs to the P(II) protein family
EAKF1_RS18045	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EAKF1_RS18045	COG1017	nitric oxide dioxygenase activity
EAKF1_RS18060	COG1940	carbohydrate kinase activity
EAKF1_RS18065	COG0457	Tetratricopeptide repeat
EAKF1_RS18070	COG1879	ABC-type sugar transport system periplasmic component
EAKF1_RS18075	COG1129	ABC transporter
EAKF1_RS18080	COG1172	Belongs to the binding-protein-dependent transport system permease family
EAKF1_RS18085	COG1063	alcohol dehydrogenase
EAKF1_RS18090	COG2017	converts alpha-aldose to the beta-anomer
EAKF1_RS18095	COG2259	Doxx family
EAKF1_RS18100	COG2814	Major facilitator Superfamily
EAKF1_RS18105	COG3711	transcriptional antiterminator
EAKF1_RS18110	COG1073	alpha beta
EAKF1_RS18115	COG0483	inositol monophosphate 1-phosphatase activity
EAKF1_RS18135	COG0822	iron-sulfur transferase activity
EAKF1_RS18155	COG0633	Ferredoxin
EAKF1_RS18160	COG2975	iron-sulfur cluster assembly
EAKF1_RS18175	COG2897	thiosulfate sulfurtransferase activity
EAKF1_RS18180	COG2373	Large extracellular alpha-helical protein
EAKF1_RS18185	COG4953	penicillin-binding protein 1C
EAKF1_RS18215	COG2976	Protein conserved in bacteria
EAKF1_RS18230	COG1645	bacterial-type flagellum-dependent swarming motility
EAKF1_RS18240	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EAKF1_RS18245	COG0582	viral genome integration into host DNA
EAKF1_RS18255	COG0517	IMP dehydrogenase activity
EAKF1_RS18255	COG0516	GMP reductase activity
EAKF1_RS18280	COG4372	Transposase
EAKF1_RS18285	COG3436	PFAM IS66 Orf2 family protein
EAKF1_RS18320	COG3133	Outer membrane lipoprotein
EAKF1_RS18335	COG2200	EAL domain
EAKF1_RS18350	COG2200	EAL domain
EAKF1_RS18355	COG0248	Ppx GppA phosphatase
EAKF1_RS18360	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EAKF1_RS18365	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EAKF1_RS18380	COG2233	PERMEase
EAKF1_RS18390	COG1393	Belongs to the ArsC family
EAKF1_RS18395	COG4783	chaperone-mediated protein folding
EAKF1_RS18400	COG0628	permease
EAKF1_RS18405	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EAKF1_RS18410	COG2716	regulation of RNA biosynthetic process
EAKF1_RS18420	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
EAKF1_RS18435	COG2321	neutral zinc metallopeptidase
EAKF1_RS18440	COG1444	tRNA N-acetyltransferase activity
EAKF1_RS18445	COG0400	carboxylic ester hydrolase activity
EAKF1_RS18460	COG1393	Belongs to the ArsC family
EAKF1_RS18470	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EAKF1_RS18475	COG3850	Histidine kinase
EAKF1_RS18480	COG0493	'glutamate synthase
EAKF1_RS18480	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EAKF1_RS18490	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EAKF1_RS18495	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EAKF1_RS18500	COG0281	malic enzyme
EAKF1_RS18500	COG0280	phosphate acetyltransferase
EAKF1_RS18505	COG4810	utilization protein
EAKF1_RS18510	COG4917	ethanolamine utilization protein
EAKF1_RS18515	COG4766	ethanolamine catabolic process
EAKF1_RS18520	COG4812	Cobalamin adenosyltransferase
EAKF1_RS18525	COG0280	phosphate acetyltransferase
EAKF1_RS18530	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
EAKF1_RS18535	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
EAKF1_RS18540	COG1012	belongs to the aldehyde dehydrogenase family
EAKF1_RS18545	COG4820	ethanolamine utilization protein (EutJ)
EAKF1_RS18550	COG1454	alcohol dehydrogenase
EAKF1_RS18560	COG4819	ethanolamine utilization protein
EAKF1_RS18565	COG4303	Ethanolamine ammonia lyase large subunit
EAKF1_RS18575	COG4816	utilization protein
EAKF1_RS18580	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
EAKF1_RS18585	COG2207	Transcriptional regulator
EAKF1_RS18620	COG0860	N-Acetylmuramoyl-L-alanine amidase
EAKF1_RS18640	COG2837	iron assimilation
EAKF1_RS18650	COG1263	PTS System
EAKF1_RS18650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EAKF1_RS18660	COG1028	Short-chain dehydrogenase reductase Sdr
EAKF1_RS18665	COG4150	thiosulfate binding
EAKF1_RS18670	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EAKF1_RS18675	COG4208	sulfate ABC transporter
EAKF1_RS18680	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EAKF1_RS18685	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EAKF1_RS18705	COG2190	(PTS) system
EAKF1_RS18710	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EAKF1_RS18715	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAKF1_RS18720	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EAKF1_RS18740	COG3530	Putative quorum-sensing-regulated virulence factor
EAKF1_RS18750	COG2211	Major facilitator Superfamily
EAKF1_RS18760	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EAKF1_RS18765	COG2211	Major facilitator Superfamily
EAKF1_RS18770	COG0583	DNA-binding transcription factor activity
EAKF1_RS18795	COG3415	Transposase
EAKF1_RS18800	COG3415	Transposase
EAKF1_RS18815	COG2200	EAL domain
EAKF1_RS18815	COG2199	diguanylate cyclase activity
EAKF1_RS18830	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EAKF1_RS18855	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EAKF1_RS18860	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EAKF1_RS18865	COG0006	proline dipeptidase activity
EAKF1_RS18870	COG1363	Peptidase, m42
EAKF1_RS18875	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAKF1_RS18875	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAKF1_RS18875	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EAKF1_RS18880	COG2207	Transcriptional regulator
EAKF1_RS18885	COG3279	Response regulator of the LytR AlgR family
EAKF1_RS18890	COG3275	phosphorelay sensor kinase activity
EAKF1_RS18895	COG0436	Aminotransferase
EAKF1_RS18900	COG1560	Kdo2-lipid A biosynthetic process
EAKF1_RS18915	COG2610	gluconate transmembrane transporter activity
EAKF1_RS18920	COG0583	DNA-binding transcription factor activity
EAKF1_RS18935	COG2853	Lipoprotein
EAKF1_RS18940	COG2067	long-chain fatty acid transport protein
EAKF1_RS18945	COG3691	Protein conserved in bacteria
EAKF1_RS18955	COG1024	Enoyl-CoA hydratase
EAKF1_RS18955	COG1250	3-hydroxyacyl-CoA dehydrogenase
EAKF1_RS18960	COG2062	phosphohistidine phosphatase, SixA
EAKF1_RS18965	COG3539	Fimbrial protein
EAKF1_RS18970	COG3188	usher protein
EAKF1_RS18975	COG3121	Chaperone
EAKF1_RS18980	COG3539	Fimbrial protein
EAKF1_RS18985	COG3539	Fimbrial protein
EAKF1_RS18990	COG3539	Fimbrial protein
EAKF1_RS19020	COG0730	response to heat
EAKF1_RS19025	COG3101	peptidyl-lysine hydroxylation
EAKF1_RS19040	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EAKF1_RS19045	COG2814	Major facilitator Superfamily
EAKF1_RS19060	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EAKF1_RS19070	COG0586	Pfam SNARE associated Golgi protein
EAKF1_RS19080	COG0285	dihydrofolate synthase activity
EAKF1_RS19085	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
EAKF1_RS19090	COG1286	toxin biosynthetic process
EAKF1_RS19095	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EAKF1_RS19100	COG0163	prenyltransferase activity
EAKF1_RS19105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAKF1_RS19110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAKF1_RS19115	COG4215	(ABC) transporter
EAKF1_RS19120	COG4160	amino acid transport
EAKF1_RS19125	COG4598	ABC transporter
EAKF1_RS19130	COG5464	transposase or invertase
EAKF1_RS19135	COG1090	epimerase
EAKF1_RS19140	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EAKF1_RS19145	COG0625	glutathione transferase activity
EAKF1_RS19155	COG0622	Phosphoesterase
EAKF1_RS19160	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EAKF1_RS19165	COG1609	Transcriptional regulator
EAKF1_RS19170	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAKF1_RS19180	COG3037	sugar-specific permease SgaT UlaA
EAKF1_RS19185	COG3959	Transketolase, thiamine diphosphate binding domain
EAKF1_RS19190	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EAKF1_RS19195	COG1288	antiporter activity
EAKF1_RS19200	COG0280	phosphate acetyltransferase
EAKF1_RS19200	COG0857	belongs to the CobB CobQ family
EAKF1_RS19205	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EAKF1_RS19225	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EAKF1_RS19230	COG0471	metal ion transport
EAKF1_RS19230	COG0490	domain, Protein
EAKF1_RS19240	COG0436	Aminotransferase
EAKF1_RS19245	COG0583	DNA-binding transcription factor activity
EAKF1_RS19265	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EAKF1_RS19270	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EAKF1_RS19275	COG1034	ATP synthesis coupled electron transport
EAKF1_RS19290	COG0839	Belongs to the complex I subunit 6 family
EAKF1_RS19300	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EAKF1_RS19305	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EAKF1_RS19320	COG2234	aminopeptidase activity
EAKF1_RS19325	COG2304	oxidoreductase activity
EAKF1_RS19335	COG2153	protein acetylation
EAKF1_RS19340	COG4575	ribosome binding
EAKF1_RS19345	COG1169	isochorismate synthase
EAKF1_RS19360	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EAKF1_RS19370	COG0318	PFAM AMP-dependent synthetase and ligase
EAKF1_RS19435	COG1414	Transcriptional regulator
EAKF1_RS19445	COG2271	Major facilitator Superfamily
EAKF1_RS19455	COG5464	transposase or invertase
EAKF1_RS19460	COG0247	lactate metabolic process
EAKF1_RS19470	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EAKF1_RS19475	COG2271	Major facilitator Superfamily
EAKF1_RS19480	COG0584	glycerophosphoryl diester phosphodiesterase
EAKF1_RS19485	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EAKF1_RS19490	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EAKF1_RS19495	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EAKF1_RS19505	COG3468	outer membrane autotransporter barrel domain protein
EAKF1_RS19515	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EAKF1_RS19520	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
EAKF1_RS19525	COG3234	Protein of unknown function (DUF1175)
EAKF1_RS19530	COG0582	viral genome integration into host DNA
EAKF1_RS19580	COG2373	Large extracellular alpha-helical protein
EAKF1_RS19590	COG4676	Protein conserved in bacteria
EAKF1_RS19595	COG0183	Belongs to the thiolase family
EAKF1_RS19605	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EAKF1_RS19610	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EAKF1_RS19615	COG2204	response regulator
EAKF1_RS19625	COG0784	Response regulator, receiver
EAKF1_RS19625	COG2205	protein histidine kinase activity
EAKF1_RS19630	COG2197	response regulator
EAKF1_RS19635	COG2198	Histidine kinase
EAKF1_RS19635	COG0642	Histidine kinase
EAKF1_RS19645	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EAKF1_RS19650	COG1477	protein flavinylation
EAKF1_RS19655	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EAKF1_RS19655	COG2169	Transcriptional regulator
EAKF1_RS19660	COG3145	DNA-N1-methyladenine dioxygenase activity
EAKF1_RS19685	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
EAKF1_RS19685	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EAKF1_RS19690	COG3062	negative regulation of establishment of protein localization
EAKF1_RS19700	COG0437	4 iron, 4 sulfur cluster binding
EAKF1_RS19705	COG0348	domain, Protein
EAKF1_RS19710	COG3043	anaerobic respiration
EAKF1_RS19715	COG3005	denitrification pathway
EAKF1_RS19720	COG4133	protoheme IX ABC transporter activity
EAKF1_RS19725	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EAKF1_RS19730	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EAKF1_RS19735	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EAKF1_RS19745	COG1138	Cytochrome C-type biogenesis protein
EAKF1_RS19750	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EAKF1_RS19755	COG4235	cytochrome complex assembly
EAKF1_RS19755	COG3088	subunit of a heme lyase
EAKF1_RS19760	COG2197	response regulator
EAKF1_RS19770	COG3468	outer membrane autotransporter barrel domain protein
EAKF1_RS19780	COG3083	sulfuric ester hydrolase activity
EAKF1_RS19805	COG3976	FMN-binding domain protein
EAKF1_RS19805	COG0431	NADPH-dependent FMN reductase
EAKF1_RS19805	COG1053	succinate dehydrogenase
EAKF1_RS19820	COG1061	Type III restriction enzyme res subunit
EAKF1_RS19825	COG1187	pseudouridine synthase activity
EAKF1_RS19840	COG4172	Belongs to the ABC transporter superfamily
EAKF1_RS19845	COG4239	(ABC) transporter, permease
EAKF1_RS19850	COG4174	ABC transporter (Permease)
EAKF1_RS19855	COG4166	transmembrane transport
EAKF1_RS19860	COG2200	EAL domain
EAKF1_RS19865	COG0791	NLP P60 protein
EAKF1_RS19870	COG0671	phosphoesterase, PA-phosphatase related
EAKF1_RS19875	COG0523	cobalamin synthesis protein
EAKF1_RS19880	COG0246	Mannitol dehydrogenase
EAKF1_RS19895	COG2814	Major facilitator Superfamily
EAKF1_RS19900	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAKF1_RS19900	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAKF1_RS19905	COG1105	Belongs to the carbohydrate kinase PfkB family
EAKF1_RS19910	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EAKF1_RS19910	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EAKF1_RS19910	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EAKF1_RS19920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EAKF1_RS19925	COG2313	pseudouridylate synthase activity
EAKF1_RS19930	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EAKF1_RS19935	COG1522	sequence-specific DNA binding
EAKF1_RS19935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EAKF1_RS19945	COG2855	membrane
EAKF1_RS19950	COG0583	DNA-binding transcription factor activity
EAKF1_RS19955	COG0833	amino acid
EAKF1_RS19965	COG4771	TonB-dependent receptor
EAKF1_RS19980	COG2311	Membrane
EAKF1_RS19990	COG1609	Transcriptional regulator
EAKF1_RS19995	COG1879	ABC-type sugar transport system periplasmic component
EAKF1_RS20000	COG1129	ABC transporter
EAKF1_RS20010	COG0167	dihydroorotate dehydrogenase activity
EAKF1_RS20010	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EAKF1_RS20015	COG0493	'glutamate synthase
EAKF1_RS20025	COG2949	membrane
EAKF1_RS20035	COG1346	cytolysis
EAKF1_RS20050	COG2271	Major facilitator Superfamily
EAKF1_RS20065	COG0625	glutathione transferase activity
EAKF1_RS20070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EAKF1_RS20075	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EAKF1_RS20095	COG0586	Pfam SNARE associated Golgi protein
EAKF1_RS20105	COG1686	Belongs to the peptidase S11 family
EAKF1_RS20110	COG0277	FAD linked oxidase domain protein
EAKF1_RS20115	COG1472	Belongs to the glycosyl hydrolase 3 family
EAKF1_RS20120	COG1732	Glycine betaine
EAKF1_RS20125	COG1174	glycine betaine transport
EAKF1_RS20130	COG1125	glycine betaine transport
EAKF1_RS20135	COG1174	glycine betaine transport
EAKF1_RS20145	COG0789	Transcriptional regulator
EAKF1_RS20150	COG3275	phosphorelay sensor kinase activity
EAKF1_RS20155	COG3279	Response regulator of the LytR AlgR family
EAKF1_RS20160	COG4807	Protein conserved in bacteria
EAKF1_RS20165	COG4808	Protein conserved in bacteria
EAKF1_RS20170	COG4715	Zinc finger, swim domain protein
EAKF1_RS20185	COG4715	Zinc finger, swim domain protein
EAKF1_RS20190	COG3552	Protein containing von Willebrand factor type A (VWA) domain
EAKF1_RS20195	COG2425	protein containing a von Willebrand factor type A (vWA) domain
EAKF1_RS20200	COG0714	Associated with various cellular activities
EAKF1_RS20215	COG3831	ATPase activity
EAKF1_RS20220	COG3831	ATPase activity
EAKF1_RS20225	COG3831	ATPase activity
EAKF1_RS20240	COG0489	protein tyrosine kinase activity
EAKF1_RS20250	COG3539	Fimbrial protein
EAKF1_RS20255	COG3121	Chaperone
EAKF1_RS20260	COG3188	usher protein
EAKF1_RS20265	COG3539	Fimbrial protein
EAKF1_RS20270	COG5455	response to cobalt ion
EAKF1_RS20300	COG3436	PFAM IS66 Orf2 family protein
EAKF1_RS20310	COG4372	Transposase
EAKF1_RS20360	COG0351	phosphomethylpyrimidine kinase
EAKF1_RS20365	COG3757	hydrolase, family 25
EAKF1_RS20390	COG2188	Transcriptional regulator
EAKF1_RS20395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EAKF1_RS20400	COG1397	ADP-ribosylglycohydrolase
EAKF1_RS20405	COG2211	Major facilitator Superfamily
EAKF1_RS20440	COG2801	Transposase and inactivated derivatives
EAKF1_RS20450	COG1830	Aldolase
EAKF1_RS20455	COG2211	Major facilitator Superfamily
EAKF1_RS20470	COG0826	peptidase U32
EAKF1_RS20485	COG0745	RESPONSE REGULATOR receiver
EAKF1_RS20490	COG2205	protein histidine kinase activity
EAKF1_RS20555	COG5301	cellulose 1,4-beta-cellobiosidase activity
EAKF1_RS20585	COG0443	Heat shock 70 kDa protein
EAKF1_RS20590	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EAKF1_RS20595	COG3447	MASE1 domain protein
EAKF1_RS20595	COG5001	Diguanylate cyclase
EAKF1_RS20595	COG5002	protein histidine kinase activity
EAKF1_RS20600	COG0572	uridine kinase
EAKF1_RS20610	COG2982	Protein involved in outer membrane biogenesis
EAKF1_RS20615	COG1253	flavin adenine dinucleotide binding
EAKF1_RS20625	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EAKF1_RS20640	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EAKF1_RS20645	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
EAKF1_RS20650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EAKF1_RS20655	COG1051	belongs to the nudix hydrolase family
EAKF1_RS20665	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EAKF1_RS20710	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EAKF1_RS20715	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EAKF1_RS20720	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
EAKF1_RS20740	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EAKF1_RS20745	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EAKF1_RS20745	COG0131	Imidazoleglycerol-phosphate dehydratase
EAKF1_RS20755	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EAKF1_RS20765	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EAKF1_RS20770	COG0583	DNA-binding transcription factor activity
EAKF1_RS20775	COG0531	amino acid
EAKF1_RS20780	COG2925	Exonuclease
EAKF1_RS20785	COG1686	Belongs to the peptidase S11 family
EAKF1_RS20795	COG1289	transmembrane transporter activity
EAKF1_RS20830	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
EAKF1_RS20895	COG1376	ErfK ybiS ycfS ynhG family protein
EAKF1_RS20905	COG0534	Mate efflux family protein
EAKF1_RS20915	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EAKF1_RS20920	COG0477	Major facilitator Superfamily
EAKF1_RS20930	COG3209	COG3209 Rhs family protein
EAKF1_RS20945	COG0583	DNA-binding transcription factor activity
EAKF1_RS20950	COG4372	Transposase
EAKF1_RS20955	COG3436	PFAM IS66 Orf2 family protein
EAKF1_RS20970	COG0583	DNA-binding transcription factor activity
EAKF1_RS21000	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EAKF1_RS21015	COG1403	HNH endonuclease
EAKF1_RS21020	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
EAKF1_RS21110	COG3436	PFAM IS66 Orf2 family protein
EAKF1_RS21115	COG4372	Transposase
EAKF1_RS21120	COG3772	lysozyme
EAKF1_RS21180	COG3443	Belongs to the bacterial solute-binding protein 9 family
EAKF1_RS21195	COG2351	hydroxyisourate hydrolase activity
EAKF1_RS21200	COG0745	RESPONSE REGULATOR receiver
EAKF1_RS21205	COG2205	protein histidine kinase activity
EAKF1_RS21215	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EAKF1_RS21235	COG0270	DNA (cytosine-5-)-methyltransferase activity
EAKF1_RS21240	COG3727	T/G mismatch-specific endonuclease activity
EAKF1_RS21245	COG0697	spore germination
EAKF1_RS21250	COG2354	Protein conserved in bacteria
EAKF1_RS21255	COG5475	Uncharacterized small protein (DUF2158)
EAKF1_RS21280	COG1684	flagellar biosynthetic protein fliR
EAKF1_RS21285	COG1987	bacterial-type flagellum assembly
EAKF1_RS21295	COG3190	flagellar
EAKF1_RS21300	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EAKF1_RS21305	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EAKF1_RS21310	COG1580	Controls the rotational direction of flagella during chemotaxis
EAKF1_RS21315	COG3144	bacterial-type flagellum assembly
EAKF1_RS21320	COG2882	bacterial-type flagellum organization
EAKF1_RS21325	COG1157	protein secretion by the type III secretion system
EAKF1_RS21330	COG1317	bacterial-type flagellum organization
EAKF1_RS21335	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EAKF1_RS21340	COG1766	The M ring may be actively involved in energy transduction
EAKF1_RS21355	COG0425	Belongs to the sulfur carrier protein TusA family
EAKF1_RS21360	COG2391	methyltransferase activity
EAKF1_RS21375	COG0366	Alpha amylase catalytic
EAKF1_RS21385	COG1516	flagellar protein fliS
EAKF1_RS21395	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EAKF1_RS21400	COG1191	sigma factor activity
EAKF1_RS21410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAKF1_RS21420	COG0765	amino acid transport
EAKF1_RS21425	COG1126	abc transporter atp-binding protein
EAKF1_RS21430	COG2197	response regulator
EAKF1_RS21445	COG2197	response regulator
EAKF1_RS21520	COG4974	Belongs to the 'phage' integrase family
EAKF1_RS21525	COG3318	Belongs to the UPF0149 family
EAKF1_RS21525	COG3012	SEC-C Motif Domain Protein
EAKF1_RS21530	COG0814	amino acid
EAKF1_RS21540	COG1528	Iron-storage protein
EAKF1_RS21560	COG1528	Iron-storage protein
EAKF1_RS21565	COG1879	ABC-type sugar transport system periplasmic component
EAKF1_RS21575	COG1172	Belongs to the binding-protein-dependent transport system permease family
EAKF1_RS21580	COG1877	trehalose-phosphatase activity
EAKF1_RS21590	COG0589	response to stress
EAKF1_RS21605	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EAKF1_RS21610	COG1360	Flagellar Motor Protein
EAKF1_RS21615	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EAKF1_RS21625	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EAKF1_RS21630	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EAKF1_RS21645	COG3102	Protein conserved in bacteria
EAKF1_RS21655	COG3005	denitrification pathway
EAKF1_RS21660	COG0243	molybdopterin cofactor binding
EAKF1_RS21675	COG3788	relative of glutathione S-transferase, MAPEG superfamily
EAKF1_RS21680	COG1801	Protein of unknown function DUF72
EAKF1_RS21685	COG1335	isochorismatase
EAKF1_RS21695	COG0494	nUDIX hydrolase
EAKF1_RS21700	COG0217	transcriptional regulatory protein
EAKF1_RS21730	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EAKF1_RS21740	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
EAKF1_RS21745	COG0739	heme binding
EAKF1_RS21750	COG1560	Kdo2-lipid A biosynthetic process
EAKF1_RS21755	COG0469	pyruvate kinase activity
EAKF1_RS21760	COG1737	Transcriptional regulator
EAKF1_RS21770	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EAKF1_RS21775	COG0129	dihydroxy-acid dehydratase activity
EAKF1_RS21780	COG0800	Aldolase
EAKF1_RS21790	COG3141	response to X-ray
EAKF1_RS21815	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EAKF1_RS21820	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EAKF1_RS21830	COG2372	response to copper ion
EAKF1_RS21835	COG1276	copper resistance
EAKF1_RS21865	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EAKF1_RS21875	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EAKF1_RS21895	COG3008	intermembrane lipid transfer
EAKF1_RS21900	COG2995	paraquat-inducible protein a
EAKF1_RS21905	COG1956	GAF domain-containing protein
EAKF1_RS21915	COG0793	Belongs to the peptidase S41A family
EAKF1_RS21925	COG2814	Major facilitator Superfamily
EAKF1_RS21930	COG1414	Transcriptional regulator
EAKF1_RS21965	COG2226	methyltransferase
EAKF1_RS21985	COG3716	PTS system mannose fructose sorbose family IID component
EAKF1_RS21990	COG3715	PTS system
EAKF1_RS21995	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EAKF1_RS21995	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAKF1_RS22005	COG1253	flavin adenine dinucleotide binding
EAKF1_RS22010	COG2200	EAL domain
EAKF1_RS22015	COG1760	l-serine dehydratase
EAKF1_RS22025	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EAKF1_RS22040	COG0251	oxidation-reduction process
EAKF1_RS22045	COG1199	ATP-dependent helicase activity
EAKF1_RS22050	COG1214	PFAM Peptidase M22, glycoprotease
EAKF1_RS22055	COG3065	identical protein binding
EAKF1_RS22060	COG0318	PFAM AMP-dependent synthetase and ligase
EAKF1_RS22065	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EAKF1_RS22070	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EAKF1_RS22075	COG4638	Rieske (2fe-2S)
EAKF1_RS22080	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EAKF1_RS22085	COG0473	3-isopropylmalate dehydrogenase activity
EAKF1_RS22090	COG0583	DNA-binding transcription factor activity
EAKF1_RS22100	COG3615	Tellurite resistance protein tehB
EAKF1_RS22115	COG2203	Gaf domain
EAKF1_RS22115	COG2199	diguanylate cyclase activity
EAKF1_RS22120	COG3042	response to heat
EAKF1_RS22125	COG3189	MarR family transcriptional regulator
EAKF1_RS22140	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EAKF1_RS22150	COG2199	diguanylate cyclase activity
EAKF1_RS22160	COG2766	serine protein kinase
EAKF1_RS22165	COG3713	MltA-interacting MipA family protein
EAKF1_RS22170	COG0676	glucose-6-phosphate 1-epimerase activity
EAKF1_RS22175	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EAKF1_RS22185	COG3139	Protein of unknown function (DUF1315)
EAKF1_RS22200	COG5433	transposase activity
EAKF1_RS22210	COG1335	isochorismatase
EAKF1_RS22215	COG0252	asparaginase activity
EAKF1_RS22225	COG0616	signal peptide processing
EAKF1_RS22230	COG0616	signal peptide processing
EAKF1_RS22235	COG0778	Nitroreductase
EAKF1_RS22250	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EAKF1_RS22255	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EAKF1_RS22265	COG3436	PFAM IS66 Orf2 family protein
EAKF1_RS22270	COG4372	Transposase
EAKF1_RS22275	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EAKF1_RS22285	COG0494	nUDIX hydrolase
EAKF1_RS22290	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EAKF1_RS22305	COG2897	thiosulfate sulfurtransferase activity
EAKF1_RS22310	COG4136	ATPase activity
EAKF1_RS22315	COG4135	transport system, permease component
EAKF1_RS22320	COG4134	Bacterial extracellular solute-binding protein
EAKF1_RS22325	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EAKF1_RS22330	COG0398	Pfam SNARE associated Golgi protein
EAKF1_RS22340	COG0398	Pfam SNARE associated Golgi protein
EAKF1_RS22345	COG0708	Exodeoxyribonuclease III
EAKF1_RS22375	COG3678	ATP-independent chaperone mediated protein folding
EAKF1_RS22395	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EAKF1_RS22400	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EAKF1_RS22405	COG1447	Phosphotransferase system cellobiose-specific component IIA
EAKF1_RS22410	COG2169	Transcriptional regulator
EAKF1_RS22410	COG1917	Cupin 2, conserved barrel domain protein
EAKF1_RS22415	COG1486	melibiose metabolic process
EAKF1_RS22420	COG3394	polysaccharide catabolic process
EAKF1_RS22435	COG1823	symporter activity
EAKF1_RS22440	COG1988	membrane-bound metal-dependent
EAKF1_RS22445	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EAKF1_RS22455	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
EAKF1_RS22460	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EAKF1_RS22465	COG3001	Fructosamine kinase
EAKF1_RS22475	COG1105	Belongs to the carbohydrate kinase PfkB family
EAKF1_RS22480	COG3137	Salt-induced outer membrane protein
EAKF1_RS22540	COG0386	Belongs to the glutathione peroxidase family
EAKF1_RS22550	COG0791	NLP P60 protein
EAKF1_RS22555	COG2200	EAL domain
EAKF1_RS22565	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EAKF1_RS22580	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EAKF1_RS22580	COG0574	Belongs to the PEP-utilizing enzyme family
EAKF1_RS22585	COG0318	PFAM AMP-dependent synthetase and ligase
EAKF1_RS22590	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
EAKF1_RS22595	COG0644	oxidoreductase
EAKF1_RS22600	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EAKF1_RS22605	COG2086	electron transfer activity
EAKF1_RS22615	COG1917	Cupin 2, conserved barrel domain protein
EAKF1_RS22615	COG2207	Transcriptional regulator
EAKF1_RS22620	COG1960	acyl-CoA dehydrogenase activity
EAKF1_RS22625	COG4670	ketone body catabolic process
EAKF1_RS22640	COG2271	Major facilitator Superfamily
EAKF1_RS22650	COG0738	Major facilitator superfamily
EAKF1_RS22660	COG0628	permease
EAKF1_RS22665	COG0277	FAD linked oxidase domain protein
EAKF1_RS22665	COG0247	lactate metabolic process
EAKF1_RS22670	COG2050	protein possibly involved in aromatic compounds catabolism
EAKF1_RS22680	COG0316	Belongs to the HesB IscA family
EAKF1_RS22685	COG0719	Fe-S assembly protein
EAKF1_RS22690	COG0396	ATPase activity
EAKF1_RS22695	COG0719	Fe-S assembly protein
EAKF1_RS22710	COG1376	ErfK ybiS ycfS ynhG family protein
EAKF1_RS22715	COG4238	major outer membrane lipoprotein
EAKF1_RS22720	COG0469	pyruvate kinase activity
EAKF1_RS22730	COG0437	4 iron, 4 sulfur cluster binding
EAKF1_RS22735	COG2414	aldehyde ferredoxin oxidoreductase
EAKF1_RS22745	COG0437	4 iron, 4 sulfur cluster binding
EAKF1_RS22750	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
EAKF1_RS22775	COG3468	outer membrane autotransporter barrel domain protein
EAKF1_RS22785	COG0307	riboflavin synthase, alpha
EAKF1_RS22790	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EAKF1_RS22795	COG2814	Major facilitator Superfamily
EAKF1_RS22800	COG0583	DNA-binding transcription factor activity
EAKF1_RS22815	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EAKF1_RS22820	COG0791	NLP P60 protein
EAKF1_RS22825	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EAKF1_RS22840	COG0346	lactoylglutathione lyase activity
EAKF1_RS22845	COG1902	pentaerythritol trinitrate reductase activity
EAKF1_RS22850	COG1309	transcriptional regulator
EAKF1_RS22855	COG3313	Fe-S protein
EAKF1_RS22860	COG4989	oxidoreductase activity
EAKF1_RS22865	COG1289	transmembrane transporter activity
EAKF1_RS22870	COG1566	PFAM secretion protein HlyD family protein
EAKF1_RS22895	COG3895	Periplasmic Protein
EAKF1_RS22910	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EAKF1_RS22915	COG0625	glutathione transferase activity
EAKF1_RS22920	COG3104	oligopeptide transport
EAKF1_RS22930	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EAKF1_RS22935	COG4660	Part of a membrane complex involved in electron transport
EAKF1_RS22940	COG4659	FMN binding
EAKF1_RS22980	COG0673	inositol 2-dehydrogenase activity
EAKF1_RS22990	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EAKF1_RS22995	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EAKF1_RS22995	COG1263	PTS System
EAKF1_RS23000	COG1609	Transcriptional regulator
EAKF1_RS23005	COG1028	Short-chain dehydrogenase reductase Sdr
EAKF1_RS23020	COG5339	Protein conserved in bacteria
EAKF1_RS23025	COG1482	cell wall glycoprotein biosynthetic process
EAKF1_RS23030	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EAKF1_RS23030	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EAKF1_RS23035	COG0114	fumarate hydratase activity
EAKF1_RS23045	COG2205	protein histidine kinase activity
EAKF1_RS23050	COG0745	RESPONSE REGULATOR receiver
EAKF1_RS23055	COG3136	membrane protein required for alginate biosynthesis
EAKF1_RS23065	COG0531	amino acid
EAKF1_RS23075	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EAKF1_RS23080	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EAKF1_RS23085	COG0628	permease
EAKF1_RS23100	COG3591	Belongs to the peptidase S1B family
EAKF1_RS23115	COG2814	Major facilitator Superfamily
EAKF1_RS23120	COG0583	DNA-binding transcription factor activity
EAKF1_RS23125	COG1940	carbohydrate kinase activity
EAKF1_RS23130	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EAKF1_RS23140	COG3381	protein complex oligomerization
EAKF1_RS23145	COG3302	dmso reductase anchor subunit
EAKF1_RS23150	COG0437	4 iron, 4 sulfur cluster binding
EAKF1_RS23155	COG0243	molybdopterin cofactor binding
EAKF1_RS23160	COG0243	molybdopterin cofactor binding
EAKF1_RS23175	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EAKF1_RS23190	COG4948	Mandelate Racemase Muconate Lactonizing
EAKF1_RS23195	COG1063	alcohol dehydrogenase
EAKF1_RS23200	COG0582	viral genome integration into host DNA
EAKF1_RS23210	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EAKF1_RS23225	COG5562	phage envelope protein
EAKF1_RS23300	COG4372	Transposase
EAKF1_RS23305	COG3436	PFAM IS66 Orf2 family protein
EAKF1_RS23315	COG0477	Major facilitator Superfamily
EAKF1_RS23320	COG0246	Mannitol dehydrogenase
EAKF1_RS23330	COG1802	Transcriptional regulator
EAKF1_RS23335	COG4221	oxidoreductase activity
EAKF1_RS23340	COG0339	signal peptide processing
EAKF1_RS23345	COG3706	GGDEF domain
EAKF1_RS23355	COG2814	Major facilitator Superfamily
EAKF1_RS23360	COG0697	spore germination
EAKF1_RS23365	COG2188	Transcriptional regulator
EAKF1_RS23375	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EAKF1_RS23385	COG2723	6-phospho-beta-galactosidase activity
EAKF1_RS23395	COG4977	sequence-specific DNA binding
EAKF1_RS23400	COG1846	Transcriptional regulator
EAKF1_RS23430	COG0583	DNA-binding transcription factor activity
EAKF1_RS23435	COG1012	belongs to the aldehyde dehydrogenase family
EAKF1_RS23440	COG2066	Belongs to the glutaminase family
EAKF1_RS23450	COG2199	diguanylate cyclase activity
EAKF1_RS23465	COG3781	membrane
EAKF1_RS23570	COG2911	Protein conserved in bacteria
EAKF1_RS23570	COG3210	domain, Protein
EAKF1_RS23590	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EAKF1_RS23590	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EAKF1_RS23590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAKF1_RS23610	COG3209	COG3209 Rhs family protein