locus-tag	class	description
CP48_RS00030	COG0460	homoserine dehydrogenase
CP48_RS00030	COG0527	aspartate kinase activity
CP48_RS00090	COG0521	Mo-molybdopterin cofactor biosynthetic process
CP48_RS00235	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CP48_RS00250	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CP48_RS00475	COG2814	Major facilitator Superfamily
CP48_RS00480	COG2814	Major facilitator Superfamily
CP48_RS00530	COG0583	DNA-binding transcription factor activity
CP48_RS00540	COG0028	Belongs to the TPP enzyme family
CP48_RS00750	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CP48_RS00795	COG3064	Membrane
CP48_RS00890	COG3188	usher protein
CP48_RS00900	COG3188	usher protein
CP48_RS00915	COG0617	tRNA 3'-terminal CCA addition
CP48_RS00960	COG4774	siderophore transport
CP48_RS00975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP48_RS01000	COG2860	membrane
CP48_RS01240	COG0587	DNA-directed DNA polymerase activity
CP48_RS01380	COG0583	DNA-binding transcription factor activity
CP48_RS01395	COG0741	lytic transglycosylase activity
CP48_RS01395	COG1388	LysM domain
CP48_RS01435	COG0527	aspartate kinase activity
CP48_RS01435	COG0460	homoserine dehydrogenase
CP48_RS01445	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CP48_RS01465	COG1115	amino acid carrier protein
CP48_RS01470	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CP48_RS01475	COG0521	Mo-molybdopterin cofactor biosynthetic process
CP48_RS01480	COG1584	GPR1 FUN34 yaaH family protein
CP48_RS01485	COG4735	regulation of single-species biofilm formation
CP48_RS01505	COG3385	transposase activity
CP48_RS01510	COG3385	transposase activity
CP48_RS01520	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CP48_RS01525	COG0583	DNA-binding transcription factor activity
CP48_RS01550	COG0196	riboflavin kinase activity
CP48_RS01565	COG1047	Peptidyl-prolyl cis-trans
CP48_RS01595	COG0505	Belongs to the CarA family
CP48_RS01600	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CP48_RS01655	COG0644	oxidoreductase
CP48_RS01660	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CP48_RS01665	COG2271	Major facilitator Superfamily
CP48_RS01680	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CP48_RS01705	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CP48_RS01710	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CP48_RS01715	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CP48_RS01720	COG0564	pseudouridine synthase activity
CP48_RS01730	COG0417	DNA replication proofreading
CP48_RS01735	COG0235	Class ii aldolase
CP48_RS01750	COG4977	sequence-specific DNA binding
CP48_RS01755	COG0586	Pfam SNARE associated Golgi protein
CP48_RS01765	COG1178	ABC-type Fe3 transport system permease component
CP48_RS01770	COG4143	(ABC) transporter
CP48_RS01785	COG2814	Major facilitator Superfamily
CP48_RS01800	COG0473	3-isopropylmalate dehydrogenase activity
CP48_RS01815	COG0583	DNA-binding transcription factor activity
CP48_RS01820	COG0028	Belongs to the TPP enzyme family
CP48_RS01825	COG0440	acetolactate synthase activity
CP48_RS01835	COG1609	Transcriptional regulator
CP48_RS01850	COG3116	cell division
CP48_RS01855	COG0768	penicillin binding
CP48_RS01860	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CP48_RS01865	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CP48_RS01875	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CP48_RS01880	COG0772	Belongs to the SEDS family
CP48_RS01895	COG1181	Belongs to the D-alanine--D-alanine ligase family
CP48_RS01900	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CP48_RS01905	COG0849	cell division
CP48_RS01910	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CP48_RS01930	COG0494	nUDIX hydrolase
CP48_RS01950	COG0237	dephospho-CoA kinase activity
CP48_RS01960	COG1459	type II secretion system
CP48_RS01965	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CP48_RS01970	COG4969	Belongs to the N-Me-Phe pilin family
CP48_RS01980	COG0157	Belongs to the NadC ModD family
CP48_RS01985	COG3023	N-Acetylmuramoyl-L-alanine amidase
CP48_RS01990	COG3725	Membrane protein required for beta-lactamase induction
CP48_RS02000	COG2186	Transcriptional regulator
CP48_RS02005	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CP48_RS02010	COG0508	dehydrogenase complex catalyzes the overall conversion of
CP48_RS02015	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CP48_RS02020	COG3064	Membrane
CP48_RS02025	COG1049	propionate catabolic process, 2-methylcitrate cycle
CP48_RS02050	COG2132	Multicopper oxidase
CP48_RS02055	COG4993	Dehydrogenase
CP48_RS02060	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CP48_RS02065	COG0288	reversible hydration of carbon dioxide
CP48_RS02070	COG1131	(ABC) transporter
CP48_RS02075	COG0842	Transport permease protein
CP48_RS02080	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP48_RS02085	COG0726	polysaccharide deacetylase
CP48_RS02095	COG5464	transposase or invertase
CP48_RS02110	COG3539	Fimbrial protein
CP48_RS02115	COG3539	Fimbrial protein
CP48_RS02120	COG3539	Fimbrial protein
CP48_RS02125	COG3539	Fimbrial protein
CP48_RS02130	COG3188	usher protein
CP48_RS02135	COG3121	Chaperone
CP48_RS02140	COG3539	Fimbrial protein
CP48_RS02145	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CP48_RS02150	COG0617	tRNA 3'-terminal CCA addition
CP48_RS02160	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CP48_RS02170	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CP48_RS02175	COG1643	Atp-dependent helicase
CP48_RS02185	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP48_RS02190	COG4774	siderophore transport
CP48_RS02195	COG1120	ATPase activity
CP48_RS02200	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CP48_RS02205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP48_RS02225	COG2860	membrane
CP48_RS02230	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CP48_RS02245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CP48_RS02250	COG3835	regulator
CP48_RS02260	COG1408	metallophosphoesterase
CP48_RS02275	COG0024	Methionine aminopeptidase
CP48_RS02300	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CP48_RS02305	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CP48_RS02310	COG0575	Belongs to the CDS family
CP48_RS02315	COG0750	zinc metalloprotease
CP48_RS02325	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CP48_RS02330	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CP48_RS02355	COG0587	DNA-directed DNA polymerase activity
CP48_RS02370	COG0346	lactoylglutathione lyase activity
CP48_RS02380	COG4568	rho-dependent transcription termination
CP48_RS02390	COG4681	YaeQ
CP48_RS02395	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CP48_RS02400	COG3015	lipoprotein NlpE involved in copper resistance
CP48_RS02405	COG0791	NLP P60 protein
CP48_RS02415	COG1720	tRNA m6t6A37 methyltransferase activity
CP48_RS02425	COG1464	Belongs to the NlpA lipoprotein family
CP48_RS02430	COG2011	ABC-type metal ion transport system permease component
CP48_RS02435	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CP48_RS02440	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CP48_RS02475	COG0656	L-ascorbic acid biosynthetic process
CP48_RS02480	COG0583	DNA-binding transcription factor activity
CP48_RS02490	COG2226	methyltransferase
CP48_RS02495	COG1388	LysM domain
CP48_RS02495	COG0741	lytic transglycosylase activity
CP48_RS02505	COG2226	methyltransferase
CP48_RS02515	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CP48_RS02535	COG4104	PAAR repeat-containing protein
CP48_RS02555	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CP48_RS02565	COG1960	acyl-CoA dehydrogenase activity
CP48_RS02575	COG0121	glutamine amidotransferase
CP48_RS02580	COG3034	peptidoglycan biosynthetic process
CP48_RS02585	COG0791	NLP P60 protein
CP48_RS02590	COG1943	Transposase
CP48_RS02615	COG0454	-acetyltransferase
CP48_RS02620	COG1690	Belongs to the RtcB family
CP48_RS02630	COG2195	Cleaves the N-terminal amino acid of tripeptides
CP48_RS02650	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CP48_RS02670	COG0582	viral genome integration into host DNA
CP48_RS02685	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CP48_RS02690	COG5532	Uncharacterized conserved protein (DUF2303)
CP48_RS02715	COG3646	Phage regulatory protein
CP48_RS02725	COG1846	Transcriptional regulator
CP48_RS02740	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CP48_RS02755	COG1403	HNH endonuclease
CP48_RS02800	COG3772	lysozyme
CP48_RS02835	COG4220	transposase activity
CP48_RS02940	COG5301	cellulose 1,4-beta-cellobiosidase activity
CP48_RS02960	COG4571	Outer membrane protease
CP48_RS02970	COG0456	acetyltransferase
CP48_RS02975	COG4372	Transposase
CP48_RS02980	COG3436	PFAM IS66 Orf2 family protein
CP48_RS03080	COG0583	DNA-binding transcription factor activity
CP48_RS03085	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CP48_RS03090	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CP48_RS03095	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CP48_RS03100	COG2080	2 iron, 2 sulfur cluster binding
CP48_RS03105	COG3477	response to acidic pH
CP48_RS03110	COG0727	PFAM Uncharacterised protein family (UPF0153)
CP48_RS03115	COG3121	Chaperone
CP48_RS03180	COG1388	LysM domain
CP48_RS03190	COG3059	membrane
CP48_RS03200	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CP48_RS03205	COG2207	Transcriptional regulator
CP48_RS03210	COG0247	lactate metabolic process
CP48_RS03215	COG1139	Iron-sulfur cluster binding protein
CP48_RS03220	COG1556	Lactate utilization protein
CP48_RS03245	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CP48_RS03255	COG2200	EAL domain
CP48_RS03255	COG2771	luxR family
CP48_RS03260	COG0583	DNA-binding transcription factor activity
CP48_RS03270	COG0666	response to abiotic stimulus
CP48_RS03280	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CP48_RS03285	COG1304	FMN binding
CP48_RS03295	COG0549	Belongs to the carbamate kinase family
CP48_RS03300	COG0402	S-adenosylhomocysteine deaminase activity
CP48_RS03305	COG1064	alcohol dehydrogenase
CP48_RS03320	COG1280	lysine exporter protein (LysE YggA)
CP48_RS03330	COG3829	transcription factor binding
CP48_RS03335	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CP48_RS03340	COG0372	Belongs to the citrate synthase family
CP48_RS03345	COG2079	MmgE PrpD family protein
CP48_RS03350	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CP48_RS03355	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CP48_RS03360	COG0402	S-adenosylhomocysteine deaminase activity
CP48_RS03365	COG0583	DNA-binding transcription factor activity
CP48_RS03370	COG0288	reversible hydration of carbon dioxide
CP48_RS03380	COG2807	transmembrane transport
CP48_RS03385	COG0110	maltose O-acetyltransferase activity
CP48_RS03390	COG2223	nitrite transmembrane transporter activity
CP48_RS03395	COG3250	beta-galactosidase activity
CP48_RS03400	COG1609	Transcriptional regulator
CP48_RS03405	COG1414	Transcriptional regulator
CP48_RS03425	COG3971	2-oxopent-4-enoate hydratase activity
CP48_RS03440	COG2814	Major facilitator Superfamily
CP48_RS03445	COG3122	Protein conserved in bacteria
CP48_RS03475	COG1215	transferase activity, transferring glycosyl groups
CP48_RS03480	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CP48_RS03490	COG2801	Transposase and inactivated derivatives
CP48_RS03495	COG4521	taurine ABC transporter
CP48_RS03500	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CP48_RS03505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CP48_RS03510	COG2175	clavaminate synthase activity
CP48_RS03515	COG0113	porphobilinogen synthase activity
CP48_RS03520	COG3468	outer membrane autotransporter barrel domain protein
CP48_RS03525	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CP48_RS03530	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CP48_RS03540	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CP48_RS03560	COG1181	Belongs to the D-alanine--D-alanine ligase family
CP48_RS03575	COG1785	Belongs to the alkaline phosphatase family
CP48_RS03585	COG3706	GGDEF domain
CP48_RS03590	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CP48_RS03615	COG4126	flavin adenine dinucleotide binding
CP48_RS03635	COG1940	carbohydrate kinase activity
CP48_RS03640	COG2814	Major facilitator Superfamily
CP48_RS03645	COG0419	ATPase involved in DNA repair
CP48_RS03650	COG0420	3'-5' exonuclease activity
CP48_RS03655	COG0745	RESPONSE REGULATOR receiver
CP48_RS03660	COG5002	protein histidine kinase activity
CP48_RS03665	COG1114	Component of the transport system for branched-chain amino acids
CP48_RS03670	COG1113	amino acid transport
CP48_RS03675	COG0366	Alpha amylase catalytic
CP48_RS03695	COG1862	Preprotein translocase
CP48_RS03700	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CP48_RS03705	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CP48_RS03710	COG1403	HNH endonuclease
CP48_RS03720	COG3248	Nucleoside-binding outer membrane protein
CP48_RS03725	COG4238	major outer membrane lipoprotein
CP48_RS03735	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CP48_RS03735	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CP48_RS03750	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CP48_RS03755	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CP48_RS03760	COG0667	Aldo Keto reductase
CP48_RS03770	COG0142	geranyltranstransferase activity
CP48_RS03785	COG0693	protein deglycase activity
CP48_RS03790	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CP48_RS03800	COG2814	Major facilitator Superfamily
CP48_RS03810	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CP48_RS03815	COG1845	cytochrome c oxidase, subunit III
CP48_RS03820	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CP48_RS03825	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CP48_RS03830	COG2223	nitrite transmembrane transporter activity
CP48_RS03835	COG3056	Lipoprotein
CP48_RS03840	COG0271	Belongs to the BolA IbaG family
CP48_RS03865	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CP48_RS03870	COG0776	regulation of translation
CP48_RS03875	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CP48_RS03880	COG1555	photosystem II stabilization
CP48_RS03885	COG0824	Thioesterase
CP48_RS03895	COG4533	DNA binding
CP48_RS03905	COG1522	sequence-specific DNA binding
CP48_RS03910	COG1132	(ABC) transporter
CP48_RS03915	COG1132	(ABC) transporter
CP48_RS03920	COG0347	Belongs to the P(II) protein family
CP48_RS03925	COG0004	ammonium transporteR
CP48_RS03930	COG1946	Acyl-CoA thioesterase
CP48_RS03935	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CP48_RS03940	COG3695	enzyme binding
CP48_RS03950	COG5507	3-demethylubiquinone-9 3-methyltransferase
CP48_RS03955	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CP48_RS03965	COG0110	maltose O-acetyltransferase activity
CP48_RS03980	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CP48_RS03985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CP48_RS03990	COG1309	transcriptional regulator
CP48_RS03995	COG1196	nuclear chromosome segregation
CP48_RS03995	COG3264	Mechanosensitive ion channel
CP48_RS04010	COG3923	Primosomal replication protein n
CP48_RS04015	COG2832	Protein of unknown function (DUF454)
CP48_RS04025	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CP48_RS04060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP48_RS04065	COG4651	solute:proton antiporter activity
CP48_RS04065	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CP48_RS04070	COG2223	nitrite transmembrane transporter activity
CP48_RS04075	COG0737	Belongs to the 5'-nucleotidase family
CP48_RS04080	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CP48_RS04085	COG3735	TraB family
CP48_RS04090	COG3093	addiction module antidote protein HigA
CP48_RS04095	COG2217	Heavy metal translocating P-type atpase
CP48_RS04105	COG0531	amino acid
CP48_RS04110	COG0789	Transcriptional regulator
CP48_RS04115	COG1585	Membrane protein implicated in regulation of membrane protease activity
CP48_RS04120	COG0330	HflC and HflK could
CP48_RS04125	COG4619	ABC transporter
CP48_RS04130	COG0390	transport system, permease component
CP48_RS04135	COG3118	belongs to the thioredoxin family
CP48_RS04140	COG0300	oxidoreductase activity
CP48_RS04145	COG2755	lipolytic protein G-D-S-L family
CP48_RS04150	COG4181	ATPase activity
CP48_RS04155	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CP48_RS04165	COG0583	DNA-binding transcription factor activity
CP48_RS04175	COG1414	Transcriptional regulator
CP48_RS04180	COG3960	tartronate-semialdehyde synthase activity
CP48_RS04185	COG3622	Belongs to the hyi family
CP48_RS04190	COG2084	Dehydrogenase
CP48_RS04195	COG1953	Uracil, thiamine, allantoin
CP48_RS04205	COG2233	PERMEase
CP48_RS04210	COG1929	Belongs to the glycerate kinase type-1 family
CP48_RS04215	COG3257	ureidoglycine aminohydrolase activity
CP48_RS04220	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP48_RS04225	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CP48_RS04230	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CP48_RS04235	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CP48_RS04245	COG0549	Belongs to the carbamate kinase family
CP48_RS04250	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CP48_RS04255	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CP48_RS04265	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CP48_RS04275	COG1988	membrane-bound metal-dependent
CP48_RS04280	COG2501	S4 domain
CP48_RS04290	COG3539	Fimbrial protein
CP48_RS04295	COG3121	Chaperone
CP48_RS04300	COG3188	usher protein
CP48_RS04310	COG3539	Fimbrial protein
CP48_RS04315	COG2197	response regulator
CP48_RS04325	COG2207	Transcriptional regulator
CP48_RS04335	COG4783	chaperone-mediated protein folding
CP48_RS04340	COG1215	transferase activity, transferring glycosyl groups
CP48_RS04365	COG3209	COG3209 Rhs family protein
CP48_RS04365	COG4104	PAAR repeat-containing protein
CP48_RS04380	COG5002	protein histidine kinase activity
CP48_RS04385	COG0745	RESPONSE REGULATOR receiver
CP48_RS04390	COG1538	Outer membrane efflux protein
CP48_RS04395	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CP48_RS04400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CP48_RS04405	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CP48_RS04410	COG1113	amino acid transport
CP48_RS04415	COG0668	transmembrane transport
CP48_RS04420	COG0778	Nitroreductase
CP48_RS04425	COG2315	Protein conserved in bacteria
CP48_RS04450	COG3385	transposase activity
CP48_RS04455	COG2977	Belongs to the P-Pant transferase superfamily
CP48_RS04460	COG4771	TonB-dependent receptor
CP48_RS04465	COG2382	esterase
CP48_RS04470	COG3251	PFAM MbtH domain protein
CP48_RS04475	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP48_RS04475	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CP48_RS04480	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CP48_RS04485	COG1120	ATPase activity
CP48_RS04490	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP48_RS04495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP48_RS04505	COG4592	Periplasmic binding protein
CP48_RS04510	COG1169	isochorismate synthase
CP48_RS04515	COG1021	2,3-dihydroxybenzoate-AMP ligase
CP48_RS04520	COG3433	isochorismatase activity
CP48_RS04520	COG1535	isochorismatase
CP48_RS04525	COG1028	Short-chain dehydrogenase reductase Sdr
CP48_RS04530	COG2050	protein possibly involved in aromatic compounds catabolism
CP48_RS04535	COG1966	Carbon starvation protein
CP48_RS04540	COG2879	small protein
CP48_RS04545	COG0371	Dehydrogenase
CP48_RS04550	COG0436	Aminotransferase
CP48_RS04555	COG1475	DNA binding
CP48_RS04560	COG3969	phosphoadenosine phosphosulfate
CP48_RS04565	COG0583	DNA-binding transcription factor activity
CP48_RS04570	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CP48_RS04575	COG0450	alkyl hydroperoxide reductase
CP48_RS04580	COG3634	alkyl hydroperoxide reductase activity
CP48_RS04585	COG0589	response to stress
CP48_RS04590	COG1063	alcohol dehydrogenase
CP48_RS04600	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CP48_RS04605	COG3719	Belongs to the RNase T2 family
CP48_RS04610	COG0471	metal ion transport
CP48_RS04625	COG3051	citrate lyase alpha subunit
CP48_RS04630	COG2301	Belongs to the HpcH HpaI aldolase family
CP48_RS04640	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
CP48_RS04645	COG3290	protein histidine kinase activity
CP48_RS04650	COG4565	transcriptional regulatory protein
CP48_RS04655	COG3069	C4-dicarboxylate transmembrane transporter activity
CP48_RS04675	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CP48_RS04680	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CP48_RS04690	COG0583	DNA-binding transcription factor activity
CP48_RS04710	COG1686	Belongs to the peptidase S11 family
CP48_RS04715	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CP48_RS04720	COG0772	Belongs to the SEDS family
CP48_RS04725	COG0768	penicillin binding
CP48_RS04735	COG0799	negative regulation of ribosome biogenesis
CP48_RS04740	COG0406	alpha-ribazole phosphatase activity
CP48_RS04750	COG1466	dna polymerase III delta subunit
CP48_RS04765	COG2888	peptidyl-tyrosine sulfation
CP48_RS04770	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CP48_RS04780	COG2214	Heat shock protein DnaJ domain protein
CP48_RS04785	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CP48_RS04795	COG2214	Heat shock protein DnaJ domain protein
CP48_RS04800	COG0443	Heat shock 70 kDa protein
CP48_RS04810	COG1126	abc transporter atp-binding protein
CP48_RS04815	COG0765	amino acid transport
CP48_RS04820	COG0765	amino acid transport
CP48_RS04825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP48_RS04835	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CP48_RS04840	COG4535	Mg2 and Co2 transporter CorC
CP48_RS04850	COG1702	phosphate starvation-inducible protein PhoH
CP48_RS04860	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP48_RS04900	COG0367	asparagine synthase
CP48_RS04905	COG0647	UMP catabolic process
CP48_RS04910	COG1940	carbohydrate kinase activity
CP48_RS04910	COG1846	Transcriptional regulator
CP48_RS04915	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CP48_RS04925	COG2190	(PTS) system
CP48_RS04925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CP48_RS04925	COG1263	PTS System
CP48_RS04945	COG0735	belongs to the Fur family
CP48_RS04960	COG0716	FMN binding
CP48_RS04970	COG0596	Alpha beta hydrolase
CP48_RS04975	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CP48_RS04980	COG0033	Phosphoglucomutase
CP48_RS05005	COG1982	Orn Lys Arg decarboxylase major
CP48_RS05015	COG0745	RESPONSE REGULATOR receiver
CP48_RS05020	COG2205	protein histidine kinase activity
CP48_RS05050	COG3209	COG3209 Rhs family protein
CP48_RS05060	COG3209	COG3209 Rhs family protein
CP48_RS05070	COG5433	transposase activity
CP48_RS05075	COG5433	transposase activity
CP48_RS05080	COG3272	Protein of unknown function (DUF1722)
CP48_RS05085	COG0415	Belongs to the DNA photolyase family
CP48_RS05095	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CP48_RS05100	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CP48_RS05105	COG1984	allophanate hydrolase subunit 2
CP48_RS05120	COG3180	Ammonia monooxygenase
CP48_RS05125	COG3539	Fimbrial protein
CP48_RS05130	COG3121	Chaperone
CP48_RS05135	COG3188	usher protein
CP48_RS05140	COG3539	Fimbrial protein
CP48_RS05145	COG0372	Belongs to the citrate synthase family
CP48_RS05155	COG2009	succinate dehydrogenase
CP48_RS05160	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CP48_RS05165	COG1053	succinate dehydrogenase
CP48_RS05170	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CP48_RS05180	COG0567	Dehydrogenase, E1 component
CP48_RS05185	COG0508	dehydrogenase complex catalyzes the overall conversion of
CP48_RS05195	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CP48_RS05200	COG2188	Transcriptional regulator
CP48_RS05205	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CP48_RS05205	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CP48_RS05205	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP48_RS05210	COG0383	alpha-mannosidase activity
CP48_RS05220	COG1271	oxidase subunit
CP48_RS05225	COG1294	oxidase, subunit
CP48_RS05230	COG4890	Cyd operon protein YbgT
CP48_RS05235	COG3790	cyd operon protein YbgE
CP48_RS05240	COG0824	Thioesterase
CP48_RS05245	COG0811	peptide transport
CP48_RS05250	COG0848	biopolymer transport protein
CP48_RS05255	COG3064	Membrane
CP48_RS05265	COG2885	chlorophyll binding
CP48_RS05270	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CP48_RS05330	COG3201	nicotinamide mononucleotide transporter
CP48_RS05335	COG1230	cation diffusion facilitator family transporter
CP48_RS05350	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CP48_RS05360	COG2017	converts alpha-aldose to the beta-anomer
CP48_RS05370	COG1085	galactose-1-phosphate uridylyltransferase
CP48_RS05375	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CP48_RS05380	COG1119	ATPase activity
CP48_RS05385	COG3585	molybdate ion transport
CP48_RS05385	COG2005	Transcriptional regulator
CP48_RS05395	COG0725	ABC transporter, periplasmic molybdate-binding protein
CP48_RS05400	COG4149	molybdate abc transporter
CP48_RS05405	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CP48_RS05410	COG0561	phosphatase activity
CP48_RS05420	COG0583	DNA-binding transcription factor activity
CP48_RS05425	COG2828	Protein conserved in bacteria
CP48_RS05430	COG0471	metal ion transport
CP48_RS05435	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CP48_RS05440	COG4677	pectinesterase activity
CP48_RS05445	COG1881	PFAM PEBP family protein
CP48_RS05450	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CP48_RS05465	COG2226	methyltransferase
CP48_RS05470	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CP48_RS05480	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CP48_RS05490	COG0521	Mo-molybdopterin cofactor biosynthetic process
CP48_RS05500	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CP48_RS05505	COG0314	molybdopterin synthase activity
CP48_RS05510	COG0670	Belongs to the BI1 family
CP48_RS05515	COG0670	Belongs to the BI1 family
CP48_RS05520	COG0392	lysyltransferase activity
CP48_RS05525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CP48_RS05530	COG3568	Endonuclease Exonuclease Phosphatase
CP48_RS05540	COG0842	Transport permease protein
CP48_RS05545	COG0842	Transport permease protein
CP48_RS05550	COG1131	(ABC) transporter
CP48_RS05560	COG1309	transcriptional regulator
CP48_RS05565	COG0513	Belongs to the DEAD box helicase family
CP48_RS05570	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
CP48_RS05575	COG1199	ATP-dependent helicase activity
CP48_RS05580	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CP48_RS05595	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CP48_RS05605	COG3385	transposase activity
CP48_RS05610	COG4774	siderophore transport
CP48_RS05625	COG0668	transmembrane transport
CP48_RS05630	COG1126	abc transporter atp-binding protein
CP48_RS05635	COG0765	amino acid transport
CP48_RS05640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP48_RS05655	COG5006	permease, DMT superfamily
CP48_RS05660	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CP48_RS05665	COG2194	sulfuric ester hydrolase activity
CP48_RS05675	COG1321	iron dependent repressor
CP48_RS05685	COG1376	ErfK ybiS ycfS ynhG family protein
CP48_RS05690	COG0488	(ABC) transporter
CP48_RS05700	COG0561	phosphatase activity
CP48_RS05705	COG1882	Formate acetyltransferase
CP48_RS05710	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CP48_RS05715	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CP48_RS05720	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CP48_RS05725	COG0303	'Molybdopterin
CP48_RS05730	COG1446	asparaginase
CP48_RS05735	COG4172	Belongs to the ABC transporter superfamily
CP48_RS05740	COG0747	negative chemotaxis
CP48_RS05755	COG2200	EAL domain
CP48_RS05760	COG2199	diguanylate cyclase activity
CP48_RS05775	COG2133	pyrroloquinoline quinone binding
CP48_RS05780	COG0625	glutathione transferase activity
CP48_RS05785	COG1686	Belongs to the peptidase S11 family
CP48_RS05790	COG1349	DNA-binding transcription factor activity
CP48_RS05795	COG0671	phosphoesterase, PA-phosphatase related
CP48_RS05800	COG2814	Major facilitator Superfamily
CP48_RS05810	COG0561	phosphatase activity
CP48_RS05815	COG0738	Major facilitator superfamily
CP48_RS05820	COG3226	Transcriptional regulator
CP48_RS05825	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CP48_RS05860	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CP48_RS05905	COG4695	Portal protein
CP48_RS05995	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CP48_RS06010	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CP48_RS06060	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CP48_RS06070	COG0778	Nitroreductase
CP48_RS06090	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CP48_RS06095	COG3842	ATPase activity
CP48_RS06100	COG1176	ABC-type spermidine putrescine transport system, permease component I
CP48_RS06105	COG1177	transmembrane transport
CP48_RS06120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP48_RS06125	COG4160	amino acid transport
CP48_RS06130	COG4215	(ABC) transporter
CP48_RS06135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP48_RS06140	COG1126	abc transporter atp-binding protein
CP48_RS06155	COG3023	N-Acetylmuramoyl-L-alanine amidase
CP48_RS06160	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CP48_RS06165	COG0702	epimerase
CP48_RS06170	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CP48_RS06175	COG0028	Belongs to the TPP enzyme family
CP48_RS06180	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CP48_RS06190	COG2431	L-lysine efflux transmembrane transporter activity
CP48_RS06205	COG3593	DNA synthesis involved in DNA repair
CP48_RS06210	COG2990	Protein conserved in bacteria
CP48_RS06215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CP48_RS06220	COG0577	efflux transmembrane transporter activity
CP48_RS06220	COG1136	(ABC) transporter
CP48_RS06225	COG1278	Cold shock
CP48_RS06235	COG0542	response to heat
CP48_RS06240	COG0582	viral genome integration into host DNA
CP48_RS06270	COG4983	Phage plasmid primase, P4 family domain protein
CP48_RS06290	COG4372	Transposase
CP48_RS06295	COG3436	PFAM IS66 Orf2 family protein
CP48_RS06305	COG2826	transposase and inactivated derivatives, IS30 family
CP48_RS06335	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CP48_RS06340	COG2194	sulfuric ester hydrolase activity
CP48_RS06355	COG0829	nickel cation binding
CP48_RS06405	COG0254	rRNA binding
CP48_RS06430	COG2433	Pfam Transposase IS66
CP48_RS06440	COG3436	PFAM IS66 Orf2 family protein
CP48_RS06445	COG4372	Transposase
CP48_RS06450	COG4372	Transposase
CP48_RS06480	COG1358	cellular component organization or biogenesis
CP48_RS06545	COG4771	TonB-dependent receptor
CP48_RS06565	COG2801	Transposase and inactivated derivatives
CP48_RS06640	COG2831	hemolysin activation secretion protein
CP48_RS06655	COG3969	phosphoadenosine phosphosulfate
CP48_RS06660	COG1475	DNA binding
CP48_RS06725	COG4372	Transposase
CP48_RS06730	COG3436	PFAM IS66 Orf2 family protein
CP48_RS06755	COG3468	outer membrane autotransporter barrel domain protein
CP48_RS06790	COG2003	Belongs to the UPF0758 family
CP48_RS06845	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CP48_RS06850	COG4988	ABC transporter
CP48_RS06855	COG0492	ferredoxin-NADP+ reductase activity
CP48_RS06860	COG1522	sequence-specific DNA binding
CP48_RS06865	COG1674	ftsk spoiiie
CP48_RS06865	COG1178	ABC-type Fe3 transport system permease component
CP48_RS06875	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CP48_RS06885	COG0243	molybdopterin cofactor binding
CP48_RS06890	COG0437	4 iron, 4 sulfur cluster binding
CP48_RS06895	COG3302	dmso reductase anchor subunit
CP48_RS06900	COG1335	isochorismatase
CP48_RS06910	COG0531	amino acid
CP48_RS06915	COG0583	DNA-binding transcription factor activity
CP48_RS06925	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CP48_RS06930	COG1882	Formate acetyltransferase
CP48_RS06935	COG2116	formate transmembrane transporter activity
CP48_RS06940	COG1944	ATP diphosphatase activity
CP48_RS06945	COG2323	membrane
CP48_RS06960	COG0501	Belongs to the peptidase M48B family
CP48_RS06970	COG0539	negative regulation of cytoplasmic translation
CP48_RS06980	COG0658	competence protein
CP48_RS06980	COG2333	competence protein COMEC
CP48_RS06985	COG1132	(ABC) transporter
CP48_RS06995	COG3214	Protein conserved in bacteria
CP48_RS07010	COG3173	Aminoglycoside phosphotransferase
CP48_RS07015	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CP48_RS07020	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CP48_RS07030	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CP48_RS07040	COG2989	Protein conserved in bacteria
CP48_RS07045	COG3108	Peptidase M15
CP48_RS07050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CP48_RS07055	COG1448	Aminotransferase
CP48_RS07080	COG0308	aminopeptidase N
CP48_RS07085	COG1116	anion transmembrane transporter activity
CP48_RS07090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CP48_RS07100	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CP48_RS07105	COG0431	NADPH-dependent FMN reductase
CP48_RS07110	COG3539	Fimbrial protein
CP48_RS07115	COG3121	Chaperone
CP48_RS07125	COG3539	Fimbrial protein
CP48_RS07130	COG3539	Fimbrial protein
CP48_RS07135	COG3539	Fimbrial protein
CP48_RS07140	COG3121	Chaperone
CP48_RS07155	COG0633	Ferredoxin
CP48_RS07155	COG3217	Mosc domain protein beta barrel domain protein
CP48_RS07165	COG0488	(ABC) transporter
CP48_RS07170	COG2995	paraquat-inducible protein a
CP48_RS07175	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CP48_RS07175	COG3008	intermembrane lipid transfer
CP48_RS07180	COG3009	Protein conserved in bacteria
CP48_RS07185	COG3130	regulation of translation
CP48_RS07195	COG1067	ATP-dependent peptidase activity
CP48_RS07220	COG3070	regulator of competence-specific genes
CP48_RS07225	COG1289	transmembrane transporter activity
CP48_RS07230	COG3304	Inner membrane component domain
CP48_RS07235	COG0210	DNA helicase
CP48_RS07255	COG1832	CoA-binding protein
CP48_RS07270	COG1254	Belongs to the acylphosphatase family
CP48_RS07275	COG2920	part of a sulfur-relay system
CP48_RS07280	COG0670	Belongs to the BI1 family
CP48_RS07290	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CP48_RS07300	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
CP48_RS07305	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CP48_RS07310	COG1999	signal sequence binding
CP48_RS07315	COG1773	rubredoxin
CP48_RS07320	COG1271	oxidase subunit
CP48_RS07325	COG1294	oxidase, subunit
CP48_RS07340	COG0489	protein tyrosine kinase activity
CP48_RS07340	COG3206	protein involved in exopolysaccharide biosynthesis
CP48_RS07345	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CP48_RS07350	COG1596	polysaccharide export
CP48_RS07355	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP48_RS07375	COG1278	Cold shock
CP48_RS07380	COG1278	Cold shock
CP48_RS07395	COG0348	domain, Protein
CP48_RS07400	COG0784	Response regulator, receiver
CP48_RS07400	COG2198	Histidine kinase
CP48_RS07400	COG2205	protein histidine kinase activity
CP48_RS07405	COG1879	ABC-type sugar transport system periplasmic component
CP48_RS07410	COG0745	RESPONSE REGULATOR receiver
CP48_RS07415	COG3005	denitrification pathway
CP48_RS07420	COG0243	molybdopterin cofactor binding
CP48_RS07425	COG3381	protein complex oligomerization
CP48_RS07465	COG3729	General stress protein
CP48_RS07470	COG2233	PERMEase
CP48_RS07505	COG1309	transcriptional regulator
CP48_RS07510	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CP48_RS07510	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CP48_RS07510	COG0506	proline dehydrogenase activity
CP48_RS07520	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CP48_RS07535	COG2822	iron ion transport
CP48_RS07550	COG1702	phosphate starvation-inducible protein PhoH
CP48_RS07555	COG3658	cytochrome
CP48_RS07580	COG3706	GGDEF domain
CP48_RS07585	COG2801	Transposase and inactivated derivatives
CP48_RS07625	COG3381	protein complex oligomerization
CP48_RS07635	COG1462	curli production assembly transport component CsgG
CP48_RS07650	COG2197	response regulator
CP48_RS07680	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CP48_RS07685	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CP48_RS07710	COG2943	transferase activity, transferring hexosyl groups
CP48_RS07715	COG5645	(Lipo)protein
CP48_RS07735	COG1560	Kdo2-lipid A biosynthetic process
CP48_RS07745	COG2353	YceI-like domain
CP48_RS07750	COG3038	cytochrome b561
CP48_RS07785	COG2999	glutathione oxidoreductase activity
CP48_RS07795	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CP48_RS07805	COG0673	inositol 2-dehydrogenase activity
CP48_RS07810	COG0728	peptidoglycan biosynthetic process
CP48_RS07815	COG3418	PFAM FlgN family protein
CP48_RS07820	COG2747	anti-sigma28 factor FlgM
CP48_RS07825	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
CP48_RS07830	COG1815	bacterial-type flagellum-dependent cell motility
CP48_RS07835	COG1558	bacterial-type flagellum-dependent cell motility
CP48_RS07840	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CP48_RS07845	COG1749	Flagellar hook protein flgE
CP48_RS07850	COG4787	bacterial-type flagellum-dependent cell motility
CP48_RS07855	COG4786	Flagellar basal body rod
CP48_RS07870	COG3951	Flagellar rod assembly protein muramidase FlgJ
CP48_RS07870	COG1705	Flagellar rod assembly protein muramidase FlgJ
CP48_RS07875	COG1256	bacterial-type flagellum assembly
CP48_RS07880	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CP48_RS07885	COG1530	ribonuclease E activity
CP48_RS07895	COG0564	pseudouridine synthase activity
CP48_RS07900	COG0424	maF-like protein
CP48_RS07905	COG1399	metal-binding, possibly nucleic acid-binding protein
CP48_RS07925	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CP48_RS07930	COG1028	Short-chain dehydrogenase reductase Sdr
CP48_RS07940	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP48_RS07945	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CP48_RS07950	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CP48_RS07960	COG0470	DNA polymerase III
CP48_RS07965	COG0084	hydrolase, TatD family'
CP48_RS07970	COG1263	PTS System
CP48_RS07970	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CP48_RS07975	COG4773	Receptor
CP48_RS07980	COG0537	adenosine 5'-monophosphoramidase activity
CP48_RS07985	COG5633	Lipoprotein
CP48_RS07990	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
CP48_RS08010	COG1252	NADH dehydrogenase
CP48_RS08015	COG3134	Outer membrane lipoprotein
CP48_RS08020	COG1309	transcriptional regulator
CP48_RS08030	COG1388	LysM domain
CP48_RS08030	COG1376	ErfK ybiS ycfS ynhG family protein
CP48_RS08035	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CP48_RS08040	COG4763	Acyl-transferase
CP48_RS08045	COG4591	ABC-type transport system involved in lipoprotein release permease component
CP48_RS08050	COG1136	(ABC) transporter
CP48_RS08055	COG4591	ABC-type transport system involved in lipoprotein release permease component
CP48_RS08065	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CP48_RS08070	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CP48_RS08090	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CP48_RS08095	COG1177	transmembrane transport
CP48_RS08100	COG0582	viral genome integration into host DNA
CP48_RS08110	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CP48_RS08145	COG4197	protein conserved in bacteria, prophage-related
CP48_RS08155	COG1846	Transcriptional regulator
CP48_RS08215	COG1403	HNH endonuclease
CP48_RS08220	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CP48_RS08230	COG2207	Transcriptional regulator
CP48_RS08275	COG3772	lysozyme
CP48_RS08310	COG0740	serine-type endopeptidase activity
CP48_RS08390	COG5301	cellulose 1,4-beta-cellobiosidase activity
CP48_RS08420	COG2850	peptidyl-arginine hydroxylation
CP48_RS08425	COG2205	protein histidine kinase activity
CP48_RS08430	COG0745	RESPONSE REGULATOR receiver
CP48_RS08435	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CP48_RS08455	COG1187	pseudouridine synthase activity
CP48_RS08460	COG0538	isocitrate dehydrogenase activity
CP48_RS08475	COG5562	phage envelope protein
CP48_RS08480	COG0789	Transcriptional regulator
CP48_RS08485	COG2200	EAL domain
CP48_RS08510	COG2200	EAL domain
CP48_RS08560	COG2894	cell division
CP48_RS08590	COG0179	Fumarylacetoacetate (FAA) hydrolase
CP48_RS08610	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CP48_RS08615	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CP48_RS08635	COG2719	SpoVR family
CP48_RS08645	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CP48_RS08655	COG1619	proteins homologs of microcin C7 resistance protein MccF
CP48_RS08665	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CP48_RS08685	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CP48_RS08685	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP48_RS08685	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CP48_RS08690	COG1461	Dihydroxyacetone kinase
CP48_RS08695	COG2376	Dihydroxyacetone kinase
CP48_RS08700	COG3284	Transcriptional regulator
CP48_RS08705	COG3468	outer membrane autotransporter barrel domain protein
CP48_RS08715	COG0012	GTP binding
CP48_RS08730	COG0659	secondary active sulfate transmembrane transporter activity
CP48_RS08735	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CP48_RS08760	COG2890	protein-(glutamine-N5) methyltransferase activity
CP48_RS08765	COG3094	Invasion gene expression up-regulator, SirB
CP48_RS08770	COG2912	Transglutaminase-like superfamily
CP48_RS08790	COG0387	Pfam Sodium calcium exchanger
CP48_RS08795	COG4572	Cation transport regulator
CP48_RS08800	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CP48_RS08805	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CP48_RS08810	COG4932	domain protein
CP48_RS08815	COG2197	response regulator
CP48_RS08820	COG3850	Histidine kinase
CP48_RS08830	COG2223	nitrite transmembrane transporter activity
CP48_RS08835	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CP48_RS08840	COG1140	nitrate reductase beta subunit
CP48_RS08845	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CP48_RS08850	COG2181	nitrate reductase activity
CP48_RS08875	COG0788	formyltetrahydrofolate deformylase activity
CP48_RS08885	COG1752	Esterase of the alpha-beta hydrolase superfamily
CP48_RS08890	COG0745	RESPONSE REGULATOR receiver
CP48_RS08895	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CP48_RS08905	COG1435	thymidine kinase activity
CP48_RS08910	COG1012	belongs to the aldehyde dehydrogenase family
CP48_RS08910	COG1454	alcohol dehydrogenase
CP48_RS08915	COG2095	MarC family integral membrane protein
CP48_RS08920	COG4166	transmembrane transport
CP48_RS08925	COG0601	transmembrane transport
CP48_RS08930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP48_RS08935	COG0444	Belongs to the ABC transporter superfamily
CP48_RS08940	COG4608	Belongs to the ABC transporter superfamily
CP48_RS08960	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CP48_RS08965	COG2350	Protein conserved in bacteria
CP48_RS08970	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CP48_RS08975	COG1607	acyl-coa hydrolase
CP48_RS08990	COG3047	cAMP biosynthetic process
CP48_RS08995	COG0582	viral genome integration into host DNA
CP48_RS09005	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CP48_RS09075	COG1846	Transcriptional regulator
CP48_RS09120	COG1403	HNH endonuclease
CP48_RS09125	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CP48_RS09130	COG0484	heat shock protein binding
CP48_RS09140	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CP48_RS09175	COG3772	lysozyme
CP48_RS09200	COG4220	transposase activity
CP48_RS09320	COG5301	cellulose 1,4-beta-cellobiosidase activity
CP48_RS09330	COG4372	Transposase
CP48_RS09350	COG3685	Protein conserved in bacteria
CP48_RS09355	COG3685	Protein conserved in bacteria
CP48_RS09360	COG3729	General stress protein
CP48_RS09375	COG0134	indole-3-glycerol-phosphate synthase activity
CP48_RS09375	COG0135	phosphoribosylanthranilate isomerase activity
CP48_RS09380	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CP48_RS09380	COG0512	Glutamine amidotransferase of anthranilate synthase
CP48_RS09385	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CP48_RS09390	COG0613	PHP domain protein
CP48_RS09395	COG0009	L-threonylcarbamoyladenylate synthase
CP48_RS09400	COG1187	pseudouridine synthase activity
CP48_RS09405	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CP48_RS09410	COG1028	Short-chain dehydrogenase reductase Sdr
CP48_RS09420	COG0616	signal peptide processing
CP48_RS09435	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CP48_RS09440	COG0583	DNA-binding transcription factor activity
CP48_RS09460	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CP48_RS09470	COG0671	phosphoesterase, PA-phosphatase related
CP48_RS09475	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CP48_RS09480	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CP48_RS09490	COG0023	Translation Initiation Factor
CP48_RS09500	COG1349	DNA-binding transcription factor activity
CP48_RS09510	COG5001	Diguanylate cyclase
CP48_RS09525	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP48_RS09525	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP48_RS09530	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CP48_RS09535	COG2852	Protein conserved in bacteria
CP48_RS09540	COG4172	Belongs to the ABC transporter superfamily
CP48_RS09545	COG4172	Belongs to the ABC transporter superfamily
CP48_RS09550	COG4171	peptide transport system, permease
CP48_RS09555	COG4168	peptide transport system, permease
CP48_RS09560	COG4166	transmembrane transport
CP48_RS09575	COG0531	amino acid
CP48_RS09580	COG0174	glutamine synthetase
CP48_RS09585	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CP48_RS09590	COG1917	Cupin 2, conserved barrel domain protein
CP48_RS09590	COG1396	sequence-specific DNA binding
CP48_RS09595	COG1012	belongs to the aldehyde dehydrogenase family
CP48_RS09600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP48_RS09605	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CP48_RS09610	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CP48_RS09615	COG1842	Phage shock protein A
CP48_RS09625	COG1983	PspC domain protein
CP48_RS09635	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CP48_RS09640	COG0366	Alpha amylase catalytic
CP48_RS09645	COG1653	transport
CP48_RS09650	COG1175	transmembrane transport
CP48_RS09655	COG0395	ABC-type sugar transport system, permease component
CP48_RS09660	COG1063	alcohol dehydrogenase
CP48_RS09665	COG1082	Xylose isomerase domain protein TIM barrel
CP48_RS09670	COG0673	inositol 2-dehydrogenase activity
CP48_RS09675	COG1554	hydrolase, family 65, central catalytic
CP48_RS09680	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CP48_RS09695	COG1609	Transcriptional regulator
CP48_RS09700	COG3106	COG3106 Predicted ATPase
CP48_RS09710	COG3283	Transcriptional regulator of aromatic amino acids metabolism
CP48_RS09715	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CP48_RS09720	COG4948	Mandelate Racemase Muconate Lactonizing
CP48_RS09725	COG2866	Carboxypeptidase
CP48_RS09730	COG0702	epimerase
CP48_RS09735	COG1073	alpha beta
CP48_RS09750	COG4166	transmembrane transport
CP48_RS09755	COG0668	transmembrane transport
CP48_RS09760	COG3182	Iron-regulated membrane protein
CP48_RS09765	COG0589	response to stress
CP48_RS09770	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CP48_RS09775	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CP48_RS09780	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CP48_RS09790	COG1473	amidohydrolase
CP48_RS09795	COG1473	amidohydrolase
CP48_RS09800	COG0583	DNA-binding transcription factor activity
CP48_RS09810	COG2840	Smr protein MutS2
CP48_RS09815	COG3706	GGDEF domain
CP48_RS09830	COG0513	Belongs to the DEAD box helicase family
CP48_RS09840	COG0589	response to stress
CP48_RS09845	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CP48_RS09850	COG1013	pyruvate-flavodoxin oxidoreductase activity
CP48_RS09850	COG0674	pyruvate-flavodoxin oxidoreductase activity
CP48_RS09850	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CP48_RS09850	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP48_RS09855	COG3042	response to heat
CP48_RS09860	COG3187	Heat shock protein
CP48_RS09865	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CP48_RS09870	COG2911	Protein conserved in bacteria
CP48_RS09880	COG3784	Protein of unknown function (DUF1318)
CP48_RS09885	COG2207	Transcriptional regulator
CP48_RS09890	COG1012	belongs to the aldehyde dehydrogenase family
CP48_RS09895	COG3733	amine oxidase
CP48_RS09900	COG2030	dehydratase
CP48_RS09900	COG1012	belongs to the aldehyde dehydrogenase family
CP48_RS09905	COG3396	Phenylacetate-CoA oxygenase
CP48_RS09910	COG3460	Phenylacetate-CoA oxygenase
CP48_RS09915	COG3396	Phenylacetate-CoA oxygenase
CP48_RS09920	COG2151	metal-sulfur cluster biosynthetic enzyme
CP48_RS09925	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CP48_RS09930	COG1024	Enoyl-CoA hydratase
CP48_RS09935	COG1024	Enoyl-CoA hydratase
CP48_RS09940	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP48_RS09945	COG2050	protein possibly involved in aromatic compounds catabolism
CP48_RS09950	COG0183	Belongs to the thiolase family
CP48_RS09955	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CP48_RS09960	COG3327	negative regulation of DNA-templated transcription, initiation
CP48_RS09965	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CP48_RS09980	COG2801	Transposase and inactivated derivatives
CP48_RS09990	COG0667	Aldo Keto reductase
CP48_RS10000	COG2267	carboxylic ester hydrolase activity
CP48_RS10005	COG2453	phosphatase
CP48_RS10005	COG0671	phosphoesterase, PA-phosphatase related
CP48_RS10015	COG1643	Atp-dependent helicase
CP48_RS10020	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CP48_RS10025	COG1012	belongs to the aldehyde dehydrogenase family
CP48_RS10030	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CP48_RS10035	COG3038	cytochrome b561
CP48_RS10050	COG0840	transmembrane signaling receptor activity
CP48_RS10055	COG0583	DNA-binding transcription factor activity
CP48_RS10060	COG5383	Protein conserved in bacteria
CP48_RS10075	COG2841	Protein conserved in bacteria
CP48_RS10080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CP48_RS10085	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CP48_RS10090	COG1275	C4-dicarboxylate transporter malic acid transport protein
CP48_RS10095	COG0500	methyltransferase
CP48_RS10115	COG0675	Transposase, IS605 OrfB family
CP48_RS10120	COG3135	benzoate transporter
CP48_RS10125	COG1396	sequence-specific DNA binding
CP48_RS10130	COG0826	peptidase U32
CP48_RS10140	COG1724	mRNA binding
CP48_RS10145	COG1598	PFAM Uncharacterised protein family UPF0150
CP48_RS10150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP48_RS10155	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CP48_RS10160	COG3842	ATPase activity
CP48_RS10165	COG1176	ABC-type spermidine putrescine transport system, permease component I
CP48_RS10170	COG1177	transmembrane transport
CP48_RS10195	COG3238	Protein conserved in bacteria
CP48_RS10200	COG1247	-acetyltransferase
CP48_RS10205	COG2130	NADP-dependent
CP48_RS10210	COG1802	Transcriptional regulator
CP48_RS10215	COG4772	TonB-dependent receptor
CP48_RS10220	COG3391	amine dehydrogenase activity
CP48_RS10225	COG1113	amino acid transport
CP48_RS10230	COG0625	glutathione transferase activity
CP48_RS10245	COG3209	COG3209 Rhs family protein
CP48_RS10275	COG5433	transposase activity
CP48_RS10300	COG5433	transposase activity
CP48_RS10310	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CP48_RS10315	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CP48_RS10320	COG0384	phenazine biosynthesis protein PhzF
CP48_RS10325	COG2181	nitrate reductase activity
CP48_RS10330	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CP48_RS10335	COG1140	nitrate reductase beta subunit
CP48_RS10340	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CP48_RS10345	COG2223	nitrite transmembrane transporter activity
CP48_RS10350	COG4886	Leucine-rich repeat (LRR) protein
CP48_RS10355	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CP48_RS10360	COG0697	spore germination
CP48_RS10365	COG3383	formate dehydrogenase (NAD+) activity
CP48_RS10365	COG0243	molybdopterin cofactor binding
CP48_RS10370	COG3383	formate dehydrogenase (NAD+) activity
CP48_RS10370	COG0243	molybdopterin cofactor binding
CP48_RS10375	COG0437	4 iron, 4 sulfur cluster binding
CP48_RS10380	COG2864	formate dehydrogenase
CP48_RS10385	COG3093	addiction module antidote protein HigA
CP48_RS10390	COG1064	alcohol dehydrogenase
CP48_RS10410	COG1764	response to oxidative stress
CP48_RS10415	COG4608	Belongs to the ABC transporter superfamily
CP48_RS10420	COG0444	Belongs to the ABC transporter superfamily
CP48_RS10425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP48_RS10430	COG0601	transmembrane transport
CP48_RS10435	COG0747	negative chemotaxis
CP48_RS10440	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CP48_RS10445	COG2200	EAL domain
CP48_RS10445	COG2202	Pas domain
CP48_RS10445	COG2199	diguanylate cyclase activity
CP48_RS10455	COG1649	PFAM Uncharacterised BCR, COG1649
CP48_RS10460	COG0531	amino acid
CP48_RS10465	COG0076	glutamate decarboxylase activity
CP48_RS10475	COG0612	Peptidase, M16
CP48_RS10480	COG4771	TonB-dependent receptor
CP48_RS10485	COG4178	(ABC) transporter
CP48_RS10490	COG0641	radical SAM
CP48_RS10495	COG3119	arylsulfatase activity
CP48_RS10500	COG2207	Transcriptional regulator
CP48_RS10510	COG0243	molybdopterin cofactor binding
CP48_RS10515	COG3539	Fimbrial protein
CP48_RS10520	COG3539	Fimbrial protein
CP48_RS10525	COG3539	Fimbrial protein
CP48_RS10540	COG3539	Fimbrial protein
CP48_RS10545	COG4977	sequence-specific DNA binding
CP48_RS10550	COG3550	peptidyl-serine autophosphorylation
CP48_RS10555	COG1396	sequence-specific DNA binding
CP48_RS10615	COG3781	membrane
CP48_RS10625	COG2199	diguanylate cyclase activity
CP48_RS10635	COG2066	Belongs to the glutaminase family
CP48_RS10640	COG1012	belongs to the aldehyde dehydrogenase family
CP48_RS10645	COG0583	DNA-binding transcription factor activity
CP48_RS10675	COG1846	Transcriptional regulator
CP48_RS10680	COG4977	sequence-specific DNA binding
CP48_RS10695	COG2814	Major facilitator Superfamily
CP48_RS10705	COG3706	GGDEF domain
CP48_RS10710	COG3111	PFAM Bacterial OB fold (BOF) protein
CP48_RS10715	COG1546	Belongs to the CinA family
CP48_RS10720	COG0339	signal peptide processing
CP48_RS10725	COG4221	oxidoreductase activity
CP48_RS10730	COG1802	Transcriptional regulator
CP48_RS10740	COG0246	Mannitol dehydrogenase
CP48_RS10745	COG0477	Major facilitator Superfamily
CP48_RS10755	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CP48_RS10760	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CP48_RS10765	COG5301	cellulose 1,4-beta-cellobiosidase activity
CP48_RS10875	COG4372	Transposase
CP48_RS10880	COG3436	PFAM IS66 Orf2 family protein
CP48_RS10895	COG5562	phage envelope protein
CP48_RS10910	COG1278	Cold shock
CP48_RS10920	COG3772	lysozyme
CP48_RS10935	COG1278	Cold shock
CP48_RS10940	COG1278	Cold shock
CP48_RS10945	COG0484	heat shock protein binding
CP48_RS10950	COG1403	HNH endonuclease
CP48_RS10970	COG2026	Addiction module toxin, RelE StbE family
CP48_RS10975	COG3077	Addiction module antitoxin, RelB DinJ family
CP48_RS10985	COG2801	Transposase and inactivated derivatives
CP48_RS10995	COG1846	Transcriptional regulator
CP48_RS11010	COG1396	sequence-specific DNA binding
CP48_RS11035	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CP48_RS11045	COG0582	viral genome integration into host DNA
CP48_RS11050	COG1063	alcohol dehydrogenase
CP48_RS11055	COG4948	Mandelate Racemase Muconate Lactonizing
CP48_RS11070	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CP48_RS11085	COG0243	molybdopterin cofactor binding
CP48_RS11090	COG0243	molybdopterin cofactor binding
CP48_RS11095	COG0437	4 iron, 4 sulfur cluster binding
CP48_RS11100	COG3302	dmso reductase anchor subunit
CP48_RS11105	COG3381	protein complex oligomerization
CP48_RS11115	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CP48_RS11120	COG1940	carbohydrate kinase activity
CP48_RS11125	COG0583	DNA-binding transcription factor activity
CP48_RS11130	COG2814	Major facilitator Superfamily
CP48_RS11145	COG3591	Belongs to the peptidase S1B family
CP48_RS11160	COG0628	permease
CP48_RS11165	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CP48_RS11170	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CP48_RS11180	COG0531	amino acid
CP48_RS11190	COG3136	membrane protein required for alginate biosynthesis
CP48_RS11195	COG0745	RESPONSE REGULATOR receiver
CP48_RS11200	COG2205	protein histidine kinase activity
CP48_RS11210	COG0114	fumarate hydratase activity
CP48_RS11215	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CP48_RS11215	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CP48_RS11220	COG1482	cell wall glycoprotein biosynthetic process
CP48_RS11225	COG5339	Protein conserved in bacteria
CP48_RS11240	COG3250	beta-galactosidase activity
CP48_RS11245	COG1309	transcriptional regulator
CP48_RS11250	COG1028	Short-chain dehydrogenase reductase Sdr
CP48_RS11255	COG1609	Transcriptional regulator
CP48_RS11260	COG1263	PTS System
CP48_RS11260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CP48_RS11265	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CP48_RS11275	COG0673	inositol 2-dehydrogenase activity
CP48_RS11315	COG4659	FMN binding
CP48_RS11325	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CP48_RS11335	COG3104	oligopeptide transport
CP48_RS11340	COG0625	glutathione transferase activity
CP48_RS11345	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CP48_RS11360	COG3895	Periplasmic Protein
CP48_RS11370	COG3133	Outer membrane lipoprotein
CP48_RS11385	COG1566	PFAM secretion protein HlyD family protein
CP48_RS11390	COG1289	transmembrane transporter activity
CP48_RS11395	COG2032	superoxide dismutase activity
CP48_RS11400	COG4989	oxidoreductase activity
CP48_RS11405	COG3313	Fe-S protein
CP48_RS11410	COG1309	transcriptional regulator
CP48_RS11415	COG1902	pentaerythritol trinitrate reductase activity
CP48_RS11420	COG0346	lactoylglutathione lyase activity
CP48_RS11430	COG1201	RNA secondary structure unwinding
CP48_RS11435	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CP48_RS11440	COG0791	NLP P60 protein
CP48_RS11445	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CP48_RS11450	COG2814	Major facilitator Superfamily
CP48_RS11465	COG0583	DNA-binding transcription factor activity
CP48_RS11470	COG2814	Major facilitator Superfamily
CP48_RS11475	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CP48_RS11480	COG0307	riboflavin synthase, alpha
CP48_RS11490	COG3468	outer membrane autotransporter barrel domain protein
CP48_RS11510	COG4529	Protein conserved in bacteria
CP48_RS11520	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
CP48_RS11525	COG0437	4 iron, 4 sulfur cluster binding
CP48_RS11535	COG2414	aldehyde ferredoxin oxidoreductase
CP48_RS11540	COG0437	4 iron, 4 sulfur cluster binding
CP48_RS11550	COG0469	pyruvate kinase activity
CP48_RS11555	COG4238	major outer membrane lipoprotein
CP48_RS11560	COG1376	ErfK ybiS ycfS ynhG family protein
CP48_RS11580	COG0396	ATPase activity
CP48_RS11585	COG0719	Fe-S assembly protein
CP48_RS11590	COG0316	Belongs to the HesB IscA family
CP48_RS11600	COG2050	protein possibly involved in aromatic compounds catabolism
CP48_RS11605	COG0277	FAD linked oxidase domain protein
CP48_RS11605	COG0247	lactate metabolic process
CP48_RS11610	COG0628	permease
CP48_RS11625	COG0738	Major facilitator superfamily
CP48_RS11630	COG2271	Major facilitator Superfamily
CP48_RS11645	COG4670	ketone body catabolic process
CP48_RS11650	COG1960	acyl-CoA dehydrogenase activity
CP48_RS11655	COG2207	Transcriptional regulator
CP48_RS11655	COG1917	Cupin 2, conserved barrel domain protein
CP48_RS11665	COG2086	electron transfer activity
CP48_RS11670	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CP48_RS11675	COG0644	oxidoreductase
CP48_RS11680	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CP48_RS11685	COG0318	PFAM AMP-dependent synthetase and ligase
CP48_RS11690	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CP48_RS11690	COG0574	Belongs to the PEP-utilizing enzyme family
CP48_RS11705	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CP48_RS11710	COG4256	Hemin uptake protein
CP48_RS11720	COG2200	EAL domain
CP48_RS11725	COG0791	NLP P60 protein
CP48_RS11735	COG0386	Belongs to the glutathione peroxidase family
CP48_RS11750	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CP48_RS11750	COG0072	phenylalanine-tRNA ligase activity
CP48_RS11795	COG3137	Salt-induced outer membrane protein
CP48_RS11800	COG1105	Belongs to the carbohydrate kinase PfkB family
CP48_RS11810	COG3001	Fructosamine kinase
CP48_RS11820	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CP48_RS11825	COG1988	membrane-bound metal-dependent
CP48_RS11830	COG1823	symporter activity
CP48_RS11845	COG0753	catalase activity
CP48_RS11855	COG1486	melibiose metabolic process
CP48_RS11860	COG1917	Cupin 2, conserved barrel domain protein
CP48_RS11860	COG2169	Transcriptional regulator
CP48_RS11865	COG1447	Phosphotransferase system cellobiose-specific component IIA
CP48_RS11870	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CP48_RS11875	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CP48_RS11880	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP48_RS11895	COG0322	excinuclease ABC activity
CP48_RS11905	COG3678	ATP-independent chaperone mediated protein folding
CP48_RS11935	COG0708	Exodeoxyribonuclease III
CP48_RS11940	COG0398	Pfam SNARE associated Golgi protein
CP48_RS11950	COG0398	Pfam SNARE associated Golgi protein
CP48_RS11955	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP48_RS11960	COG4134	Bacterial extracellular solute-binding protein
CP48_RS11965	COG4135	transport system, permease component
CP48_RS11970	COG4136	ATPase activity
CP48_RS11975	COG2897	thiosulfate sulfurtransferase activity
CP48_RS11980	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CP48_RS11985	COG0494	nUDIX hydrolase
CP48_RS11995	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CP48_RS12005	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CP48_RS12020	COG0778	Nitroreductase
CP48_RS12030	COG0616	signal peptide processing
CP48_RS12035	COG0252	asparaginase activity
CP48_RS12040	COG1335	isochorismatase
CP48_RS12045	COG2814	Major facilitator Superfamily
CP48_RS12050	COG1349	DNA-binding transcription factor activity
CP48_RS12055	COG0667	Aldo Keto reductase
CP48_RS12060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP48_RS12065	COG0191	fructose-bisphosphate aldolase activity
CP48_RS12070	COG1063	alcohol dehydrogenase
CP48_RS12075	COG2271	Major facilitator Superfamily
CP48_RS12085	COG3139	Protein of unknown function (DUF1315)
CP48_RS12095	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CP48_RS12100	COG0676	glucose-6-phosphate 1-epimerase activity
CP48_RS12105	COG0656	L-ascorbic acid biosynthetic process
CP48_RS12110	COG3713	MltA-interacting MipA family protein
CP48_RS12115	COG2766	serine protein kinase
CP48_RS12125	COG2199	diguanylate cyclase activity
CP48_RS12130	COG2199	diguanylate cyclase activity
CP48_RS12135	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CP48_RS12150	COG2207	Transcriptional regulator
CP48_RS12155	COG2807	transmembrane transport
CP48_RS12160	COG3189	MarR family transcriptional regulator
CP48_RS12165	COG3042	response to heat
CP48_RS12170	COG2203	Gaf domain
CP48_RS12170	COG2199	diguanylate cyclase activity
CP48_RS12180	COG2261	transglycosylase associated protein
CP48_RS12190	COG3615	Tellurite resistance protein tehB
CP48_RS12195	COG3385	transposase activity
CP48_RS12200	COG3615	Tellurite resistance protein tehB
CP48_RS12210	COG0583	DNA-binding transcription factor activity
CP48_RS12215	COG0473	3-isopropylmalate dehydrogenase activity
CP48_RS12220	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CP48_RS12225	COG4638	Rieske (2fe-2S)
CP48_RS12230	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CP48_RS12235	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CP48_RS12240	COG0318	PFAM AMP-dependent synthetase and ligase
CP48_RS12245	COG3065	identical protein binding
CP48_RS12250	COG1214	PFAM Peptidase M22, glycoprotease
CP48_RS12255	COG1199	ATP-dependent helicase activity
CP48_RS12260	COG0251	oxidation-reduction process
CP48_RS12280	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CP48_RS12290	COG1760	l-serine dehydratase
CP48_RS12295	COG2200	EAL domain
CP48_RS12300	COG1253	flavin adenine dinucleotide binding
CP48_RS12310	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CP48_RS12310	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP48_RS12315	COG3715	PTS system
CP48_RS12320	COG3716	PTS system mannose fructose sorbose family IID component
CP48_RS12340	COG2226	methyltransferase
CP48_RS12375	COG1414	Transcriptional regulator
CP48_RS12380	COG2814	Major facilitator Superfamily
CP48_RS12390	COG0793	Belongs to the peptidase S41A family
CP48_RS12400	COG1956	GAF domain-containing protein
CP48_RS12405	COG2995	paraquat-inducible protein a
CP48_RS12410	COG3008	intermembrane lipid transfer
CP48_RS12430	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CP48_RS12445	COG1276	copper resistance
CP48_RS12450	COG2372	response to copper ion
CP48_RS12460	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CP48_RS12465	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CP48_RS12470	COG1770	oligopeptidase
CP48_RS12475	COG2979	Protein of unknown function (DUF533)
CP48_RS12490	COG3141	response to X-ray
CP48_RS12500	COG0800	Aldolase
CP48_RS12505	COG0129	dihydroxy-acid dehydratase activity
CP48_RS12510	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CP48_RS12520	COG1737	Transcriptional regulator
CP48_RS12525	COG0469	pyruvate kinase activity
CP48_RS12530	COG1560	Kdo2-lipid A biosynthetic process
CP48_RS12535	COG0739	heme binding
CP48_RS12540	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CP48_RS12550	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CP48_RS12575	COG0217	transcriptional regulatory protein
CP48_RS12580	COG0494	nUDIX hydrolase
CP48_RS12590	COG1335	isochorismatase
CP48_RS12605	COG5301	cellulose 1,4-beta-cellobiosidase activity
CP48_RS12710	COG4220	transposase activity
CP48_RS12740	COG3772	lysozyme
CP48_RS12790	COG2207	Transcriptional regulator
CP48_RS12815	COG0305	Participates in initiation and elongation during chromosome replication
CP48_RS12820	COG1484	DNA-dependent DNA replication
CP48_RS12855	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CP48_RS12905	COG0582	viral genome integration into host DNA
CP48_RS12910	COG1801	Protein of unknown function DUF72
CP48_RS12915	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CP48_RS12930	COG0243	molybdopterin cofactor binding
CP48_RS12935	COG3005	denitrification pathway
CP48_RS12945	COG3102	Protein conserved in bacteria
CP48_RS12955	COG3755	Protein conserved in bacteria
CP48_RS12965	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CP48_RS12970	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CP48_RS12975	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CP48_RS12980	COG0745	RESPONSE REGULATOR receiver
CP48_RS12990	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CP48_RS12995	COG0840	transmembrane signaling receptor activity
CP48_RS13000	COG0840	transmembrane signaling receptor activity
CP48_RS13005	COG0835	chemotaxis
CP48_RS13010	COG2198	Histidine kinase
CP48_RS13010	COG0643	Histidine kinase
CP48_RS13015	COG1360	Flagellar Motor Protein
CP48_RS13020	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CP48_RS13035	COG0589	response to stress
CP48_RS13045	COG1877	trehalose-phosphatase activity
CP48_RS13050	COG1172	Belongs to the binding-protein-dependent transport system permease family
CP48_RS13055	COG1129	ABC transporter
CP48_RS13060	COG1879	ABC-type sugar transport system periplasmic component
CP48_RS13065	COG1528	Iron-storage protein
CP48_RS13085	COG1528	Iron-storage protein
CP48_RS13095	COG0814	amino acid
CP48_RS13100	COG3318	Belongs to the UPF0149 family
CP48_RS13100	COG3012	SEC-C Motif Domain Protein
CP48_RS13125	COG3385	transposase activity
CP48_RS13130	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CP48_RS13135	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CP48_RS13160	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CP48_RS13165	COG3012	SEC-C Motif Domain Protein
CP48_RS13165	COG3318	Belongs to the UPF0149 family
CP48_RS13275	COG2197	response regulator
CP48_RS13290	COG2197	response regulator
CP48_RS13295	COG1126	abc transporter atp-binding protein
CP48_RS13300	COG0765	amino acid transport
CP48_RS13310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP48_RS13320	COG1191	sigma factor activity
CP48_RS13335	COG1516	flagellar protein fliS
CP48_RS13345	COG0366	Alpha amylase catalytic
CP48_RS13355	COG2391	methyltransferase activity
CP48_RS13360	COG0425	Belongs to the sulfur carrier protein TusA family
CP48_RS13365	COG2135	peptidase activity
CP48_RS13370	COG0675	Transposase, IS605 OrfB family
CP48_RS13380	COG2207	Transcriptional regulator
CP48_RS13385	COG1881	PFAM PEBP family protein
CP48_RS13390	COG2076	Multidrug Resistance protein
CP48_RS13405	COG1766	The M ring may be actively involved in energy transduction
CP48_RS13410	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CP48_RS13415	COG1317	bacterial-type flagellum organization
CP48_RS13420	COG1157	protein secretion by the type III secretion system
CP48_RS13425	COG2882	bacterial-type flagellum organization
CP48_RS13430	COG3144	bacterial-type flagellum assembly
CP48_RS13435	COG1580	Controls the rotational direction of flagella during chemotaxis
CP48_RS13440	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CP48_RS13445	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CP48_RS13450	COG3190	flagellar
CP48_RS13455	COG1338	Plays a role in the flagellum-specific transport system
CP48_RS13460	COG1987	bacterial-type flagellum assembly
CP48_RS13465	COG1684	flagellar biosynthetic protein fliR
CP48_RS13470	COG2197	response regulator
CP48_RS13495	COG5475	Uncharacterized small protein (DUF2158)
CP48_RS13500	COG2354	Protein conserved in bacteria
CP48_RS13505	COG0697	spore germination
CP48_RS13510	COG3727	T/G mismatch-specific endonuclease activity
CP48_RS13515	COG0270	DNA (cytosine-5-)-methyltransferase activity
CP48_RS13520	COG1418	mRNA catabolic process
CP48_RS13530	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CP48_RS13545	COG2205	protein histidine kinase activity
CP48_RS13550	COG0745	RESPONSE REGULATOR receiver
CP48_RS13555	COG2351	hydroxyisourate hydrolase activity
CP48_RS13570	COG3443	Belongs to the bacterial solute-binding protein 9 family
CP48_RS13580	COG3729	General stress protein
CP48_RS13585	COG3685	Protein conserved in bacteria
CP48_RS13590	COG3685	Protein conserved in bacteria
CP48_RS13595	COG3546	catalase activity
CP48_RS13610	COG5301	cellulose 1,4-beta-cellobiosidase activity
CP48_RS13730	COG4220	transposase activity
CP48_RS13790	COG2207	Transcriptional regulator
CP48_RS13800	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CP48_RS13805	COG1403	HNH endonuclease
CP48_RS13830	COG1846	Transcriptional regulator
CP48_RS13855	COG1396	sequence-specific DNA binding
CP48_RS13880	COG3646	Phage regulatory protein
CP48_RS13895	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CP48_RS13925	COG0582	viral genome integration into host DNA
CP48_RS13930	COG1169	isochorismate synthase
CP48_RS13935	COG2814	Major facilitator Superfamily
CP48_RS13940	COG1132	(ABC) transporter
CP48_RS13955	COG2226	methyltransferase
CP48_RS13955	COG3433	isochorismatase activity
CP48_RS13955	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP48_RS13975	COG1021	2,3-dihydroxybenzoate-AMP ligase
CP48_RS13980	COG4771	TonB-dependent receptor
CP48_RS13985	COG2373	Large extracellular alpha-helical protein
CP48_RS13985	COG4932	domain protein
CP48_RS13985	COG1388	LysM domain
CP48_RS13990	COG1470	cell adhesion involved in biofilm formation
CP48_RS13990	COG1388	LysM domain
CP48_RS13995	COG1470	cell adhesion involved in biofilm formation
CP48_RS13995	COG1388	LysM domain
CP48_RS14005	COG0477	Major facilitator Superfamily
CP48_RS14010	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CP48_RS14015	COG0217	transcriptional regulatory protein
CP48_RS14025	COG0534	Mate efflux family protein
CP48_RS14035	COG0583	DNA-binding transcription factor activity
CP48_RS14040	COG0583	DNA-binding transcription factor activity
CP48_RS14050	COG1376	ErfK ybiS ycfS ynhG family protein
CP48_RS14065	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
CP48_RS14080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP48_RS14095	COG1735	metal-dependent hydrolase with the TIM-barrel fold
CP48_RS14100	COG0405	Gamma-glutamyltransferase
CP48_RS14185	COG4372	Transposase
CP48_RS14195	COG3436	PFAM IS66 Orf2 family protein
CP48_RS14225	COG3436	PFAM IS66 Orf2 family protein
CP48_RS14230	COG4372	Transposase
CP48_RS14270	COG2003	Belongs to the UPF0758 family
CP48_RS14310	COG1289	transmembrane transporter activity
CP48_RS14320	COG1686	Belongs to the peptidase S11 family
CP48_RS14325	COG2925	Exonuclease
CP48_RS14330	COG0425	Belongs to the sulfur carrier protein TusA family
CP48_RS14335	COG2391	methyltransferase activity
CP48_RS14340	COG0531	amino acid
CP48_RS14345	COG0583	DNA-binding transcription factor activity
CP48_RS14350	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CP48_RS14360	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CP48_RS14370	COG0131	Imidazoleglycerol-phosphate dehydratase
CP48_RS14370	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CP48_RS14375	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CP48_RS14400	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CP48_RS14405	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CP48_RS14410	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CP48_RS14435	COG2089	acid synthase
CP48_RS14440	COG1083	cytidylyl-transferase
CP48_RS14445	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CP48_RS14450	COG1086	Polysaccharide biosynthesis protein
CP48_RS14455	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CP48_RS14465	COG0438	transferase activity, transferring glycosyl groups
CP48_RS14470	COG2327	Polysaccharide pyruvyl transferase
CP48_RS14475	COG2244	polysaccharide biosynthetic process
CP48_RS14480	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CP48_RS14485	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CP48_RS14490	COG0662	Cupin 2, conserved barrel domain protein
CP48_RS14490	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CP48_RS14495	COG0297	glycogen (starch) synthase activity
CP48_RS14500	COG1051	belongs to the nudix hydrolase family
CP48_RS14505	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CP48_RS14510	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CP48_RS14515	COG0110	maltose O-acetyltransferase activity
CP48_RS14520	COG1216	Glycosyl transferase, family 2
CP48_RS14530	COG0438	transferase activity, transferring glycosyl groups
CP48_RS14535	COG1045	serine acetyltransferase
CP48_RS14540	COG0463	Glycosyl transferase, family 2
CP48_RS14545	COG3206	protein involved in exopolysaccharide biosynthesis
CP48_RS14545	COG0489	protein tyrosine kinase activity
CP48_RS14550	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CP48_RS14555	COG1596	polysaccharide export
CP48_RS14560	COG1253	flavin adenine dinucleotide binding
CP48_RS14565	COG2982	Protein involved in outer membrane biogenesis
CP48_RS14575	COG0572	uridine kinase
CP48_RS14580	COG3447	MASE1 domain protein
CP48_RS14580	COG5002	protein histidine kinase activity
CP48_RS14580	COG5001	Diguanylate cyclase
CP48_RS14585	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CP48_RS14590	COG0443	Heat shock 70 kDa protein
CP48_RS14595	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
CP48_RS14600	COG0631	protein serine/threonine phosphatase activity
CP48_RS14605	COG4245	von Willebrand factor, type A
CP48_RS14610	COG3385	transposase activity
CP48_RS14635	COG2205	protein histidine kinase activity
CP48_RS14640	COG0745	RESPONSE REGULATOR receiver
CP48_RS14650	COG0826	peptidase U32
CP48_RS14675	COG1063	alcohol dehydrogenase
CP48_RS14680	COG3775	system Galactitol-specific IIC component
CP48_RS14685	COG3414	Phosphotransferase system galactitol-specific IIB component
CP48_RS14690	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP48_RS14705	COG1830	Aldolase
CP48_RS14710	COG2211	Major facilitator Superfamily
CP48_RS14715	COG1397	ADP-ribosylglycohydrolase
CP48_RS14720	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP48_RS14725	COG2188	Transcriptional regulator
CP48_RS14730	COG3757	hydrolase, family 25
CP48_RS14735	COG0351	phosphomethylpyrimidine kinase
CP48_RS14750	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CP48_RS14755	COG5455	response to cobalt ion
CP48_RS14760	COG3539	Fimbrial protein
CP48_RS14765	COG3188	usher protein
CP48_RS14770	COG3121	Chaperone
CP48_RS14775	COG3539	Fimbrial protein
CP48_RS14790	COG0489	protein tyrosine kinase activity
CP48_RS14800	COG3831	ATPase activity
CP48_RS14805	COG3831	ATPase activity
CP48_RS14810	COG3831	ATPase activity
CP48_RS14830	COG0714	Associated with various cellular activities
CP48_RS14835	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CP48_RS14840	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CP48_RS14845	COG3552	Protein containing von Willebrand factor type A (VWA) domain
CP48_RS14850	COG4715	Zinc finger, swim domain protein
CP48_RS14855	COG4808	Protein conserved in bacteria
CP48_RS14860	COG4807	Protein conserved in bacteria
CP48_RS14865	COG3279	Response regulator of the LytR AlgR family
CP48_RS14870	COG3275	phosphorelay sensor kinase activity
CP48_RS14875	COG0789	Transcriptional regulator
CP48_RS14885	COG1174	glycine betaine transport
CP48_RS14890	COG1125	glycine betaine transport
CP48_RS14895	COG1174	glycine betaine transport
CP48_RS14900	COG1732	Glycine betaine
CP48_RS14905	COG1472	Belongs to the glycosyl hydrolase 3 family
CP48_RS14910	COG0277	FAD linked oxidase domain protein
CP48_RS14915	COG1686	Belongs to the peptidase S11 family
CP48_RS14925	COG0586	Pfam SNARE associated Golgi protein
CP48_RS14930	COG1028	Short-chain dehydrogenase reductase Sdr
CP48_RS14945	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CP48_RS14955	COG1346	cytolysis
CP48_RS14965	COG2949	membrane
CP48_RS14975	COG0493	'glutamate synthase
CP48_RS14980	COG0167	dihydroorotate dehydrogenase activity
CP48_RS14980	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CP48_RS14985	COG4211	Belongs to the binding-protein-dependent transport system permease family
CP48_RS14990	COG1129	ABC transporter
CP48_RS14995	COG1879	ABC-type sugar transport system periplasmic component
CP48_RS15000	COG1609	Transcriptional regulator
CP48_RS15010	COG2311	Membrane
CP48_RS15030	COG4771	TonB-dependent receptor
CP48_RS15040	COG0833	amino acid
CP48_RS15045	COG0583	DNA-binding transcription factor activity
CP48_RS15050	COG2855	membrane
CP48_RS15060	COG1522	sequence-specific DNA binding
CP48_RS15060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP48_RS15065	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CP48_RS15075	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CP48_RS15080	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CP48_RS15085	COG2313	pseudouridylate synthase activity
CP48_RS15090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP48_RS15095	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CP48_RS15095	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CP48_RS15095	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CP48_RS15100	COG1105	Belongs to the carbohydrate kinase PfkB family
CP48_RS15105	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP48_RS15105	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP48_RS15110	COG2814	Major facilitator Superfamily
CP48_RS15125	COG0246	Mannitol dehydrogenase
CP48_RS15130	COG0523	cobalamin synthesis protein
CP48_RS15135	COG0671	phosphoesterase, PA-phosphatase related
CP48_RS15140	COG0791	NLP P60 protein
CP48_RS15145	COG2200	EAL domain
CP48_RS15150	COG4166	transmembrane transport
CP48_RS15155	COG4174	ABC transporter (Permease)
CP48_RS15160	COG4239	(ABC) transporter, permease
CP48_RS15165	COG4172	Belongs to the ABC transporter superfamily
CP48_RS15175	COG2814	Major facilitator Superfamily
CP48_RS15180	COG1187	pseudouridine synthase activity
CP48_RS15185	COG1061	Type III restriction enzyme res subunit
CP48_RS15205	COG3083	sulfuric ester hydrolase activity
CP48_RS15215	COG0582	viral genome integration into host DNA
CP48_RS15270	COG0740	serine-type endopeptidase activity
CP48_RS15300	COG3468	outer membrane autotransporter barrel domain protein
CP48_RS15305	COG3468	outer membrane autotransporter barrel domain protein
CP48_RS15310	COG3468	outer membrane autotransporter barrel domain protein
CP48_RS15320	COG2197	response regulator
CP48_RS15325	COG4235	cytochrome complex assembly
CP48_RS15325	COG3088	subunit of a heme lyase
CP48_RS15330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CP48_RS15335	COG1138	Cytochrome C-type biogenesis protein
CP48_RS15345	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CP48_RS15350	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CP48_RS15355	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CP48_RS15360	COG4133	protoheme IX ABC transporter activity
CP48_RS15365	COG3005	denitrification pathway
CP48_RS15370	COG3043	anaerobic respiration
CP48_RS15375	COG0348	domain, Protein
CP48_RS15380	COG0437	4 iron, 4 sulfur cluster binding
CP48_RS15390	COG3062	negative regulation of establishment of protein localization
CP48_RS15395	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CP48_RS15395	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
CP48_RS15415	COG4615	Cyclic peptide transporter
CP48_RS15420	COG3145	DNA-N1-methyladenine dioxygenase activity
CP48_RS15425	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CP48_RS15425	COG2169	Transcriptional regulator
CP48_RS15430	COG1477	protein flavinylation
CP48_RS15450	COG0642	Histidine kinase
CP48_RS15450	COG2198	Histidine kinase
CP48_RS15455	COG2197	response regulator
CP48_RS15460	COG2205	protein histidine kinase activity
CP48_RS15460	COG0784	Response regulator, receiver
CP48_RS15465	COG3852	Histidine kinase
CP48_RS15470	COG2204	response regulator
CP48_RS15475	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CP48_RS15480	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CP48_RS15485	COG2031	fatty acid transporter
CP48_RS15490	COG0183	Belongs to the thiolase family
CP48_RS15495	COG4676	Protein conserved in bacteria
CP48_RS15500	COG5445	Predicted secreted protein (DUF2300)
CP48_RS15505	COG2373	Large extracellular alpha-helical protein
CP48_RS15510	COG3234	Protein of unknown function (DUF1175)
CP48_RS15515	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
CP48_RS15520	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CP48_RS15530	COG3468	outer membrane autotransporter barrel domain protein
CP48_RS15540	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CP48_RS15545	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CP48_RS15550	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CP48_RS15555	COG3642	lipopolysaccharide core region biosynthetic process
CP48_RS15560	COG0583	DNA-binding transcription factor activity
CP48_RS15565	COG0584	glycerophosphoryl diester phosphodiesterase
CP48_RS15570	COG2271	Major facilitator Superfamily
CP48_RS15575	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CP48_RS15585	COG0247	lactate metabolic process
CP48_RS15590	COG5464	transposase or invertase
CP48_RS15600	COG2271	Major facilitator Superfamily
CP48_RS15610	COG1414	Transcriptional regulator
CP48_RS15675	COG0318	PFAM AMP-dependent synthetase and ligase
CP48_RS15685	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CP48_RS15700	COG1169	isochorismate synthase
CP48_RS15705	COG4575	ribosome binding
CP48_RS15710	COG2153	protein acetylation
CP48_RS15725	COG2234	aminopeptidase activity
CP48_RS15740	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP48_RS15745	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CP48_RS15755	COG0839	Belongs to the complex I subunit 6 family
CP48_RS15770	COG1034	ATP synthesis coupled electron transport
CP48_RS15775	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CP48_RS15780	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CP48_RS15800	COG0583	DNA-binding transcription factor activity
CP48_RS15805	COG0436	Aminotransferase
CP48_RS15815	COG0490	domain, Protein
CP48_RS15815	COG0471	metal ion transport
CP48_RS15820	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CP48_RS15840	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CP48_RS15845	COG0857	belongs to the CobB CobQ family
CP48_RS15845	COG0280	phosphate acetyltransferase
CP48_RS15850	COG1288	antiporter activity
CP48_RS15855	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CP48_RS15860	COG0622	Phosphoesterase
CP48_RS15865	COG0625	glutathione transferase activity
CP48_RS15870	COG0625	glutathione transferase activity
CP48_RS15875	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CP48_RS15880	COG1090	epimerase
CP48_RS15890	COG4598	ABC transporter
CP48_RS15895	COG4160	amino acid transport
CP48_RS15900	COG4215	(ABC) transporter
CP48_RS15905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP48_RS15910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP48_RS15915	COG0163	prenyltransferase activity
CP48_RS15920	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CP48_RS15925	COG1286	toxin biosynthetic process
CP48_RS15930	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CP48_RS15935	COG0285	dihydrofolate synthase activity
CP48_RS15945	COG0586	Pfam SNARE associated Golgi protein
CP48_RS15955	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CP48_RS15970	COG2814	Major facilitator Superfamily
CP48_RS15975	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP48_RS15990	COG3101	peptidyl-lysine hydroxylation
CP48_RS15995	COG0730	response to heat
CP48_RS16010	COG2890	protein-(glutamine-N5) methyltransferase activity
CP48_RS16025	COG3539	Fimbrial protein
CP48_RS16030	COG3539	Fimbrial protein
CP48_RS16035	COG3539	Fimbrial protein
CP48_RS16040	COG3121	Chaperone
CP48_RS16045	COG3188	usher protein
CP48_RS16050	COG3539	Fimbrial protein
CP48_RS16055	COG2062	phosphohistidine phosphatase, SixA
CP48_RS16070	COG3691	Protein conserved in bacteria
CP48_RS16075	COG2067	long-chain fatty acid transport protein
CP48_RS16085	COG2853	Lipoprotein
CP48_RS16090	COG2116	formate transmembrane transporter activity
CP48_RS16100	COG0583	DNA-binding transcription factor activity
CP48_RS16105	COG2610	gluconate transmembrane transporter activity
CP48_RS16115	COG0477	Major facilitator Superfamily
CP48_RS16120	COG1566	PFAM secretion protein HlyD family protein
CP48_RS16125	COG2197	response regulator
CP48_RS16130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP48_RS16130	COG2205	protein histidine kinase activity
CP48_RS16130	COG2198	Histidine kinase
CP48_RS16130	COG0784	Response regulator, receiver
CP48_RS16135	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP48_RS16140	COG0679	Auxin Efflux Carrier
CP48_RS16145	COG0028	Belongs to the TPP enzyme family
CP48_RS16175	COG1560	Kdo2-lipid A biosynthetic process
CP48_RS16180	COG0436	Aminotransferase
CP48_RS16185	COG3275	phosphorelay sensor kinase activity
CP48_RS16190	COG3279	Response regulator of the LytR AlgR family
CP48_RS16195	COG2207	Transcriptional regulator
CP48_RS16200	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP48_RS16200	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CP48_RS16200	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP48_RS16205	COG1363	Peptidase, m42
CP48_RS16210	COG0006	proline dipeptidase activity
CP48_RS16220	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CP48_RS16250	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CP48_RS16255	COG3385	transposase activity
CP48_RS16260	COG2199	diguanylate cyclase activity
CP48_RS16260	COG2200	EAL domain
CP48_RS16275	COG3415	Transposase
CP48_RS16280	COG3415	Transposase
CP48_RS16315	COG0583	DNA-binding transcription factor activity
CP48_RS16325	COG2211	Major facilitator Superfamily
CP48_RS16330	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CP48_RS16340	COG0583	DNA-binding transcription factor activity
CP48_RS16345	COG0385	Bile acid
CP48_RS16350	COG3530	Putative quorum-sensing-regulated virulence factor
CP48_RS16370	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CP48_RS16375	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP48_RS16380	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CP48_RS16385	COG2190	(PTS) system
CP48_RS16400	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CP48_RS16405	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CP48_RS16410	COG4208	sulfate ABC transporter
CP48_RS16415	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CP48_RS16420	COG4150	thiosulfate binding
CP48_RS16425	COG1028	Short-chain dehydrogenase reductase Sdr
CP48_RS16440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CP48_RS16440	COG1263	PTS System
CP48_RS16445	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CP48_RS16450	COG2837	iron assimilation
CP48_RS16470	COG0860	N-Acetylmuramoyl-L-alanine amidase
CP48_RS16480	COG2207	Transcriptional regulator
CP48_RS16485	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CP48_RS16490	COG4816	utilization protein
CP48_RS16500	COG4303	Ethanolamine ammonia lyase large subunit
CP48_RS16505	COG4819	ethanolamine utilization protein
CP48_RS16510	COG3192	ethanolamine utilization protein
CP48_RS16515	COG1454	alcohol dehydrogenase
CP48_RS16520	COG4820	ethanolamine utilization protein (EutJ)
CP48_RS16525	COG1012	belongs to the aldehyde dehydrogenase family
CP48_RS16530	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
CP48_RS16535	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CP48_RS16540	COG0280	phosphate acetyltransferase
CP48_RS16545	COG4812	Cobalamin adenosyltransferase
CP48_RS16550	COG4766	ethanolamine catabolic process
CP48_RS16555	COG4917	ethanolamine utilization protein
CP48_RS16560	COG4810	utilization protein
CP48_RS16565	COG0280	phosphate acetyltransferase
CP48_RS16565	COG0281	malic enzyme
CP48_RS16570	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CP48_RS16575	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CP48_RS16580	COG5342	invasion associated locus B
CP48_RS16590	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CP48_RS16590	COG0493	'glutamate synthase
CP48_RS16595	COG3850	Histidine kinase
CP48_RS16600	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CP48_RS16610	COG1393	Belongs to the ArsC family
CP48_RS16625	COG0400	carboxylic ester hydrolase activity
CP48_RS16635	COG2321	neutral zinc metallopeptidase
CP48_RS16650	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CP48_RS16660	COG2716	regulation of RNA biosynthetic process
CP48_RS16665	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CP48_RS16670	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CP48_RS16675	COG3385	transposase activity
CP48_RS16680	COG0651	ATP synthesis coupled electron transport
CP48_RS16685	COG0651	ATP synthesis coupled electron transport
CP48_RS16690	COG0650	Formate hydrogenlyase subunit 4
CP48_RS16695	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CP48_RS16700	COG4237	Hydrogenase 4 membrane
CP48_RS16705	COG0651	ATP synthesis coupled electron transport
CP48_RS16710	COG0651	ATP synthesis coupled electron transport
CP48_RS16715	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CP48_RS16715	COG3261	NADH dehydrogenase
CP48_RS16720	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP48_RS16735	COG3604	Transcriptional regulator
CP48_RS16740	COG2116	formate transmembrane transporter activity
CP48_RS16745	COG0628	permease
CP48_RS16750	COG4783	chaperone-mediated protein folding
CP48_RS16755	COG1393	Belongs to the ArsC family
CP48_RS16765	COG2233	PERMEase
CP48_RS16780	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CP48_RS16785	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CP48_RS16790	COG0248	Ppx GppA phosphatase
CP48_RS16795	COG2200	EAL domain
CP48_RS16810	COG3133	Outer membrane lipoprotein
CP48_RS16825	COG0517	IMP dehydrogenase activity
CP48_RS16825	COG0516	GMP reductase activity
CP48_RS16835	COG1645	bacterial-type flagellum-dependent swarming motility
CP48_RS16850	COG2976	Protein conserved in bacteria
CP48_RS16880	COG4953	penicillin-binding protein 1C
CP48_RS16885	COG2373	Large extracellular alpha-helical protein
CP48_RS16905	COG2975	iron-sulfur cluster assembly
CP48_RS16910	COG0633	Ferredoxin
CP48_RS16930	COG0822	iron-sulfur transferase activity
CP48_RS16950	COG0483	inositol monophosphate 1-phosphatase activity
CP48_RS16955	COG1073	alpha beta
CP48_RS16960	COG3711	transcriptional antiterminator
CP48_RS16965	COG2814	Major facilitator Superfamily
CP48_RS16970	COG0583	DNA-binding transcription factor activity
CP48_RS16975	COG4638	Rieske (2fe-2S)
CP48_RS17000	COG2259	Doxx family
CP48_RS17005	COG2017	converts alpha-aldose to the beta-anomer
CP48_RS17010	COG1063	alcohol dehydrogenase
CP48_RS17015	COG1172	Belongs to the binding-protein-dependent transport system permease family
CP48_RS17020	COG1129	ABC transporter
CP48_RS17025	COG1879	ABC-type sugar transport system periplasmic component
CP48_RS17030	COG0457	Tetratricopeptide repeat
CP48_RS17035	COG1940	carbohydrate kinase activity
CP48_RS17045	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CP48_RS17045	COG1017	nitric oxide dioxygenase activity
CP48_RS17050	COG0347	Belongs to the P(II) protein family
CP48_RS17055	COG2204	response regulator
CP48_RS17060	COG3170	Tfp pilus assembly protein FimV
CP48_RS17065	COG2205	protein histidine kinase activity
CP48_RS17070	COG0047	phosphoribosylformylglycinamidine synthase activity
CP48_RS17070	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CP48_RS17085	COG0560	Phosphoserine phosphatase
CP48_RS17090	COG1737	Transcriptional regulator
CP48_RS17095	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CP48_RS17120	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CP48_RS17140	COG0681	Belongs to the peptidase S26 family
CP48_RS17150	COG3086	response to oxidative stress
CP48_RS17155	COG3026	antisigma factor binding
CP48_RS17160	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
CP48_RS17165	COG1595	DNA-templated transcription, initiation
CP48_RS17175	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CP48_RS17185	COG0513	Belongs to the DEAD box helicase family
CP48_RS17195	COG0583	DNA-binding transcription factor activity
CP48_RS17215	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CP48_RS17225	COG3118	belongs to the thioredoxin family
CP48_RS17230	COG3148	PFAM DTW domain containing protein
CP48_RS17235	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CP48_RS17235	COG1042	CoA-binding domain protein
CP48_RS17235	COG0045	succinate-CoA ligase (ADP-forming) activity
CP48_RS17240	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CP48_RS17245	COG5544	Lipoprotein
CP48_RS17250	COG0477	Major facilitator Superfamily
CP48_RS17280	COG0542	response to heat
CP48_RS17285	COG1496	oxidoreductase activity
CP48_RS17290	COG0564	pseudouridine synthase activity
CP48_RS17295	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP48_RS17305	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CP48_RS17310	COG1605	Chorismate mutase
CP48_RS17310	COG0077	Prephenate dehydratase
CP48_RS17315	COG0287	Prephenate dehydrogenase
CP48_RS17315	COG1605	Chorismate mutase
CP48_RS17320	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CP48_RS17335	COG2199	diguanylate cyclase activity
CP48_RS17340	COG2885	chlorophyll binding
CP48_RS17365	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CP48_RS17370	COG4137	Cytochrome C assembly protein
CP48_RS17375	COG4536	flavin adenine dinucleotide binding
CP48_RS17390	COG0497	DNA recombination
CP48_RS17395	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP48_RS17405	COG2867	negative regulation of translational initiation
CP48_RS17420	COG3468	outer membrane autotransporter barrel domain protein
CP48_RS17455	COG0579	oxidoreductase
CP48_RS17460	COG1012	belongs to the aldehyde dehydrogenase family
CP48_RS17465	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CP48_RS17470	COG1113	amino acid transport
CP48_RS17475	COG1802	Transcriptional regulator
CP48_RS17480	COG1652	LysM domain
CP48_RS17485	COG0401	homolog of Blt101
CP48_RS17490	COG0640	Transcriptional regulator
CP48_RS17495	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CP48_RS17500	COG2916	Histone family protein nucleoid-structuring protein H-NS
CP48_RS17515	COG4575	ribosome binding
CP48_RS17520	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CP48_RS17530	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CP48_RS17535	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CP48_RS17540	COG4175	Glycine betaine
CP48_RS17545	COG4176	ABC-type proline glycine betaine transport system permease component
CP48_RS17550	COG2113	Glycine betaine
CP48_RS17555	COG2814	Major facilitator Superfamily
CP48_RS17560	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CP48_RS17570	COG1846	Transcriptional regulator
CP48_RS17575	COG1566	PFAM secretion protein HlyD family protein
CP48_RS17580	COG2814	Major facilitator Superfamily
CP48_RS17595	COG1238	metal cluster binding
CP48_RS17600	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CP48_RS17630	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CP48_RS17655	COG1546	Belongs to the CinA family
CP48_RS17660	COG2951	lytic endotransglycosylase activity
CP48_RS17665	COG3730	PTS system glucitol sorbitol-specific
CP48_RS17670	COG3732	PTS system glucitol sorbitol-specific
CP48_RS17680	COG1028	Short-chain dehydrogenase reductase Sdr
CP48_RS17685	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP48_RS17690	COG1349	DNA-binding transcription factor activity
CP48_RS17695	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CP48_RS17695	COG0517	IMP dehydrogenase activity
CP48_RS17715	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CP48_RS17720	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CP48_RS17725	COG1609	Transcriptional regulator
CP48_RS17730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CP48_RS17730	COG1263	PTS System
CP48_RS17735	COG2723	6-phospho-beta-galactosidase activity
CP48_RS17740	COG5499	transcription regulator containing HTH domain
CP48_RS17745	COG4680	protein conserved in bacteria
CP48_RS17755	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CP48_RS17765	COG3260	NADH ubiquinone oxidoreductase 20
CP48_RS17770	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP48_RS17775	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CP48_RS17775	COG3261	NADH dehydrogenase
CP48_RS17780	COG0650	Formate hydrogenlyase subunit 4
CP48_RS17785	COG0651	ATP synthesis coupled electron transport
CP48_RS17790	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CP48_RS17805	COG0375	protein maturation
CP48_RS17810	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CP48_RS17815	COG0298	carbon dioxide binding
CP48_RS17820	COG0409	Hydrogenase expression formation protein
CP48_RS17825	COG0309	Hydrogenase expression formation protein (HypE)
CP48_RS17830	COG3604	Transcriptional regulator
CP48_RS17845	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CP48_RS17850	COG1349	DNA-binding transcription factor activity
CP48_RS17855	COG2084	Dehydrogenase
CP48_RS17860	COG3395	kinase activity
CP48_RS17865	COG0235	Class ii aldolase
CP48_RS17870	COG3622	Belongs to the hyi family
CP48_RS17875	COG2610	gluconate transmembrane transporter activity
CP48_RS17880	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CP48_RS17885	COG4942	peptidase
CP48_RS17885	COG1388	LysM domain
CP48_RS17940	COG2234	aminopeptidase activity
CP48_RS17945	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CP48_RS17950	COG1518	maintenance of DNA repeat elements
CP48_RS17965	COG1857	crispr-associated protein
CP48_RS17985	COG3385	transposase activity
CP48_RS17990	COG3385	transposase activity
CP48_RS18015	COG0720	synthase
CP48_RS18020	COG0644	oxidoreductase
CP48_RS18025	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CP48_RS18030	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CP48_RS18035	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CP48_RS18040	COG2086	electron transfer activity
CP48_RS18045	COG0477	Major facilitator Superfamily
CP48_RS18050	COG0277	FAD linked oxidase domain protein
CP48_RS18055	COG1028	Short-chain dehydrogenase reductase Sdr
CP48_RS18060	COG2223	nitrite transmembrane transporter activity
CP48_RS18065	COG1070	Carbohydrate kinase
CP48_RS18070	COG0602	queuosine metabolic process
CP48_RS18080	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CP48_RS18095	COG3956	TIGRFAM MazG family protein
CP48_RS18100	COG2337	Toxic component of a toxin-antitoxin (TA) module
CP48_RS18105	COG2336	PFAM SpoVT AbrB
CP48_RS18110	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CP48_RS18115	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CP48_RS18120	COG4999	Histidine kinase
CP48_RS18120	COG3437	response regulator, receiver
CP48_RS18120	COG3850	Histidine kinase
CP48_RS18120	COG2205	protein histidine kinase activity
CP48_RS18125	COG4948	Mandelate Racemase Muconate Lactonizing
CP48_RS18130	COG4948	Mandelate Racemase Muconate Lactonizing
CP48_RS18135	COG2271	Major facilitator Superfamily
CP48_RS18140	COG0716	FMN binding
CP48_RS18145	COG0564	pseudouridine synthase activity
CP48_RS18150	COG3098	single-species biofilm formation
CP48_RS18170	COG1611	Belongs to the LOG family
CP48_RS18175	COG0814	amino acid
CP48_RS18180	COG1760	l-serine dehydratase
CP48_RS18190	COG1454	alcohol dehydrogenase
CP48_RS18195	COG0235	Class ii aldolase
CP48_RS18200	COG0738	Major facilitator superfamily
CP48_RS18210	COG1070	Carbohydrate kinase
CP48_RS18220	COG1349	DNA-binding transcription factor activity
CP48_RS18230	COG2363	Small membrane protein
CP48_RS18235	COG0583	DNA-binding transcription factor activity
CP48_RS18245	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CP48_RS18250	COG2166	iron-sulfur cluster assembly
CP48_RS18255	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CP48_RS18260	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CP48_RS18280	COG0860	N-Acetylmuramoyl-L-alanine amidase
CP48_RS18285	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CP48_RS18285	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CP48_RS18290	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CP48_RS18295	COG1074	ATP-dependent DNA helicase activity
CP48_RS18305	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CP48_RS18310	COG4967	type IV pilus modification protein PilV
CP48_RS18320	COG4795	General secretion pathway protein
CP48_RS18325	COG2165	general secretion pathway protein
CP48_RS18340	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
CP48_RS18365	COG0861	Integral membrane protein TerC family
CP48_RS18375	COG0667	Aldo Keto reductase
CP48_RS18390	COG1609	Transcriptional regulator
CP48_RS18400	COG0583	DNA-binding transcription factor activity
CP48_RS18405	COG1794	racemase activity, acting on amino acids and derivatives
CP48_RS18410	COG2814	Major facilitator Superfamily
CP48_RS18415	COG1028	Short-chain dehydrogenase reductase Sdr
CP48_RS18425	COG0183	Belongs to the thiolase family
CP48_RS18430	COG0814	amino acid
CP48_RS18445	COG2771	luxR family
CP48_RS18450	COG3710	Transcriptional regulator
CP48_RS18470	COG0457	Tetratricopeptide repeat
CP48_RS18475	COG3710	Transcriptional regulator
CP48_RS18475	COG0457	Tetratricopeptide repeat
CP48_RS18490	COG2197	response regulator
CP48_RS18495	COG2197	response regulator
CP48_RS18615	COG3387	PFAM Glycoside hydrolase 15-related
CP48_RS18715	COG0582	viral genome integration into host DNA
CP48_RS18815	COG4942	peptidase
CP48_RS18820	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CP48_RS18825	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CP48_RS18830	COG2080	2 iron, 2 sulfur cluster binding
CP48_RS18835	COG3829	transcription factor binding
CP48_RS18840	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CP48_RS18845	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CP48_RS18850	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP48_RS18860	COG0549	Belongs to the carbamate kinase family
CP48_RS18865	COG3608	succinylglutamate desuccinylase aspartoacylase
CP48_RS18865	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CP48_RS18870	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CP48_RS18875	COG2068	MobA-Related Protein
CP48_RS18880	COG0493	'glutamate synthase
CP48_RS18880	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CP48_RS18885	COG0402	S-adenosylhomocysteine deaminase activity
CP48_RS18890	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CP48_RS18895	COG2080	2 iron, 2 sulfur cluster binding
CP48_RS18895	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CP48_RS18900	COG2233	PERMEase
CP48_RS18905	COG0402	S-adenosylhomocysteine deaminase activity
CP48_RS18910	COG2252	PERMEase
CP48_RS18915	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CP48_RS18920	COG0493	'glutamate synthase
CP48_RS18920	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CP48_RS18930	COG2233	PERMEase
CP48_RS18945	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CP48_RS18955	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CP48_RS18960	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CP48_RS18965	COG4974	Belongs to the 'phage' integrase family
CP48_RS18970	COG0716	FMN binding
CP48_RS18980	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CP48_RS18990	COG1272	protein, Hemolysin III
CP48_RS19000	COG2723	6-phospho-beta-galactosidase activity
CP48_RS19005	COG1028	Short-chain dehydrogenase reductase Sdr
CP48_RS19025	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP48_RS19030	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP48_RS19035	COG0006	proline dipeptidase activity
CP48_RS19055	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CP48_RS19065	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CP48_RS19080	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP48_RS19080	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP48_RS19085	COG1703	isobutyryl-CoA mutase activity
CP48_RS19090	COG1024	Enoyl-CoA hydratase
CP48_RS19095	COG0427	acetyl-CoA hydrolase
CP48_RS19100	COG0583	DNA-binding transcription factor activity
CP48_RS19105	COG2968	Membrane
CP48_RS19115	COG0668	transmembrane transport
CP48_RS19120	COG0191	fructose-bisphosphate aldolase activity
CP48_RS19135	COG1072	(Pantothenic acid kinase))
CP48_RS19140	COG3722	fumarate hydratase activity
CP48_RS19145	COG1494	fructose-1,6-bisphosphatase
CP48_RS19150	COG1063	alcohol dehydrogenase
CP48_RS19155	COG2213	PTS system mannitol-specific
CP48_RS19160	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP48_RS19165	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CP48_RS19170	COG0501	Belongs to the peptidase M48B family
CP48_RS19185	COG1166	arginine decarboxylase activity
CP48_RS19210	COG2814	Major facilitator Superfamily
CP48_RS19220	COG2356	endonuclease I
CP48_RS19225	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CP48_RS19230	COG0189	ligase activity
CP48_RS19245	COG2805	Type II/IV secretion system protein
CP48_RS19250	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CP48_RS19255	COG0762	integral membrane protein
CP48_RS19270	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CP48_RS19280	COG0252	asparaginase activity
CP48_RS19295	COG3171	Protein conserved in bacteria
CP48_RS19305	COG1194	a g-specific adenine glycosylase
CP48_RS19320	COG2211	Major facilitator Superfamily
CP48_RS19325	COG1982	Orn Lys Arg decarboxylase major
CP48_RS19330	COG1811	Na channel or pump
CP48_RS19340	COG0582	viral genome integration into host DNA
CP48_RS19345	COG0582	viral genome integration into host DNA
CP48_RS19355	COG3436	PFAM IS66 Orf2 family protein
CP48_RS19360	COG4372	Transposase
CP48_RS19370	COG2255	four-way junction helicase activity
CP48_RS19395	COG3436	PFAM IS66 Orf2 family protein
CP48_RS19405	COG0582	viral genome integration into host DNA
CP48_RS19410	COG2194	sulfuric ester hydrolase activity
CP48_RS19415	COG4372	Transposase
CP48_RS19420	COG3436	PFAM IS66 Orf2 family protein
CP48_RS19455	COG3210	domain, Protein
CP48_RS19465	COG3210	domain, Protein
CP48_RS19470	COG3210	domain, Protein
CP48_RS19485	COG4372	Transposase
CP48_RS19495	COG2994	toxin metabolic process
CP48_RS19500	COG2831	hemolysin activation secretion protein
CP48_RS19580	COG3468	outer membrane autotransporter barrel domain protein
CP48_RS19595	COG2003	Belongs to the UPF0758 family
CP48_RS19630	COG3609	addiction module antidote protein, CC2985 family
CP48_RS19640	COG0582	viral genome integration into host DNA
CP48_RS19645	COG2194	sulfuric ester hydrolase activity
CP48_RS19670	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CP48_RS19700	COG2165	general secretion pathway protein
CP48_RS19705	COG1459	type II secretion system
CP48_RS19710	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CP48_RS19735	COG3064	Membrane
CP48_RS19745	COG1620	l-lactate permease
CP48_RS19755	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CP48_RS19760	COG0247	lactate metabolic process
CP48_RS19770	COG0277	FAD linked oxidase domain protein
CP48_RS19775	COG2186	Transcriptional regulator
CP48_RS19780	COG0456	acetyltransferase
CP48_RS19785	COG0318	PFAM AMP-dependent synthetase and ligase
CP48_RS19795	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP48_RS19800	COG0156	8-amino-7-oxononanoate synthase activity
CP48_RS19810	COG0795	lipopolysaccharide-transporting ATPase activity
CP48_RS19815	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CP48_RS19825	COG2244	polysaccharide biosynthetic process
CP48_RS19830	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CP48_RS19835	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CP48_RS19840	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CP48_RS19845	COG0306	phosphate transporter
CP48_RS19850	COG0754	glutathionylspermidine amidase activity
CP48_RS19855	COG0625	glutathione transferase activity
CP48_RS19860	COG0298	carbon dioxide binding
CP48_RS19870	COG1773	rubredoxin
CP48_RS19875	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CP48_RS19880	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CP48_RS19885	COG5557	Pfam Polysulphide reductase, NrfD
CP48_RS19890	COG0437	4 iron, 4 sulfur cluster binding
CP48_RS19895	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CP48_RS19915	COG0667	Aldo Keto reductase
CP48_RS19925	COG1028	Short-chain dehydrogenase reductase Sdr
CP48_RS19930	COG0848	biopolymer transport protein
CP48_RS19935	COG0811	peptide transport
CP48_RS19945	COG0626	cystathionine gamma-synthase activity
CP48_RS19950	COG0586	Pfam SNARE associated Golgi protein
CP48_RS19955	COG2207	Transcriptional regulator
CP48_RS19965	COG1979	alcohol dehydrogenase
CP48_RS19970	COG0656	L-ascorbic acid biosynthetic process
CP48_RS19980	COG4238	major outer membrane lipoprotein
CP48_RS19985	COG1032	radical SAM domain protein
CP48_RS19990	COG2132	Multicopper oxidase
CP48_RS19995	COG0204	Acyl-transferase
CP48_RS20000	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CP48_RS20005	COG4166	transmembrane transport
CP48_RS20010	COG2944	sequence-specific DNA binding
CP48_RS20020	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CP48_RS20025	COG3111	PFAM Bacterial OB fold (BOF) protein
CP48_RS20030	COG0745	RESPONSE REGULATOR receiver
CP48_RS20035	COG0642	Histidine kinase
CP48_RS20055	COG2249	NAD(P)H dehydrogenase (quinone) activity
CP48_RS20060	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CP48_RS20065	COG0187	DNA topoisomerase II activity
CP48_RS20070	COG3150	esterase
CP48_RS20075	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CP48_RS20080	COG3151	Protein conserved in bacteria
CP48_RS20085	COG0494	nUDIX hydrolase
CP48_RS20090	COG1538	Outer membrane efflux protein
CP48_RS20105	COG0754	glutathionylspermidine amidase activity
CP48_RS20110	COG3384	dioxygenase
CP48_RS20130	COG2960	long-chain fatty acid transporting porin activity
CP48_RS20135	COG3539	Fimbrial protein
CP48_RS20140	COG3188	usher protein
CP48_RS20145	COG3121	Chaperone
CP48_RS20150	COG3539	Fimbrial protein
CP48_RS20160	COG1585	Membrane protein implicated in regulation of membrane protease activity
CP48_RS20165	COG2268	Band 7 protein
CP48_RS20185	COG3025	triphosphatase activity
CP48_RS20195	COG4991	sh3 domain protein
CP48_RS20210	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CP48_RS20220	COG0583	DNA-binding transcription factor activity
CP48_RS20225	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CP48_RS20230	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CP48_RS20235	COG0471	metal ion transport
CP48_RS20245	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CP48_RS20250	COG0358	DNA primase activity
CP48_RS20255	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CP48_RS20270	COG2375	cellular response to nickel ion
CP48_RS20275	COG1695	Transcriptional regulator
CP48_RS20280	COG0840	transmembrane signaling receptor activity
CP48_RS20290	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CP48_RS20295	COG1609	Transcriptional regulator
CP48_RS20300	COG3250	beta-galactosidase activity
CP48_RS20305	COG2731	YhcH YjgK YiaL family protein
CP48_RS20310	COG0531	amino acid
CP48_RS20320	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
CP48_RS20320	COG3408	Glycogen debranching enzyme
CP48_RS20325	COG1902	pentaerythritol trinitrate reductase activity
CP48_RS20325	COG0446	pyridine nucleotide-disulphide oxidoreductase
CP48_RS20335	COG1451	nucleotide metabolic process
CP48_RS20340	COG2949	membrane
CP48_RS20345	COG0673	inositol 2-dehydrogenase activity
CP48_RS20350	COG0861	Integral membrane protein TerC family
CP48_RS20355	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CP48_RS20365	COG2721	sulfolactate sulfo-lyase activity
CP48_RS20375	COG2271	Major facilitator Superfamily
CP48_RS20415	COG2186	Transcriptional regulator
CP48_RS20420	COG0586	Pfam SNARE associated Golgi protein
CP48_RS20430	COG1422	Protein of unknown function (DUF1090)
CP48_RS20435	COG4575	ribosome binding
CP48_RS20440	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CP48_RS20450	COG2259	Doxx family
CP48_RS20455	COG0435	Glutathione S-transferase
CP48_RS20460	COG3152	Membrane
CP48_RS20465	COG3152	Membrane
CP48_RS20470	COG0583	DNA-binding transcription factor activity
CP48_RS20475	COG1741	Belongs to the pirin family
CP48_RS20490	COG0814	amino acid
CP48_RS20495	COG1760	l-serine dehydratase
CP48_RS20500	COG0251	oxidation-reduction process
CP48_RS20505	COG1882	Formate acetyltransferase
CP48_RS20510	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CP48_RS20520	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CP48_RS20525	COG0583	DNA-binding transcription factor activity
CP48_RS20550	COG1929	Belongs to the glycerate kinase type-1 family
CP48_RS20555	COG2084	Dehydrogenase
CP48_RS20565	COG2271	Major facilitator Superfamily
CP48_RS20570	COG2721	sulfolactate sulfo-lyase activity
CP48_RS20575	COG2002	toxin-antitoxin pair type II binding
CP48_RS20585	COG1349	DNA-binding transcription factor activity
CP48_RS20595	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CP48_RS20605	COG3716	PTS system mannose fructose sorbose family IID component
CP48_RS20610	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP48_RS20615	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CP48_RS20620	COG2222	sugar isomerase
CP48_RS20630	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CP48_RS20635	COG3715	PTS system
CP48_RS20640	COG3716	PTS system mannose fructose sorbose family IID component
CP48_RS20645	COG0363	glucosamine-6-phosphate deaminase activity
CP48_RS20650	COG3539	Fimbrial protein
CP48_RS20655	COG3121	Chaperone
CP48_RS20660	COG3188	usher protein
CP48_RS20665	COG3539	Fimbrial protein
CP48_RS20670	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CP48_RS20675	COG3107	peptidoglycan biosynthetic process
CP48_RS20690	COG2823	Periplasmic or secreted lipoprotein
CP48_RS20695	COG0701	Predicted permease
CP48_RS20700	COG0702	epimerase
CP48_RS20705	COG0693	protein deglycase activity
CP48_RS20720	COG3153	acetyltransferase
CP48_RS20725	COG3154	lipid carrier protein
CP48_RS20730	COG0826	peptidase U32
CP48_RS20735	COG0826	peptidase U32
CP48_RS20740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP48_RS20745	COG0814	amino acid
CP48_RS20755	COG0513	Belongs to the DEAD box helicase family
CP48_RS20790	COG0195	Participates in both transcription termination and antitermination
CP48_RS20810	COG2194	sulfuric ester hydrolase activity
CP48_RS20820	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CP48_RS20830	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CP48_RS20835	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CP48_RS20845	COG1534	Rna-binding protein
CP48_RS20850	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CP48_RS20855	COG2027	D-alanyl-D-alanine carboxypeptidase
CP48_RS20865	COG0697	spore germination
CP48_RS20880	COG0142	geranyltranstransferase activity
CP48_RS20885	COG3423	Transcriptional regulator
CP48_RS20895	COG5007	Belongs to the BolA IbaG family
CP48_RS20900	COG3113	response to antibiotic
CP48_RS20905	COG2854	intermembrane phospholipid transfer
CP48_RS20910	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CP48_RS20915	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CP48_RS20920	COG1127	ABC transporter
CP48_RS20925	COG0530	calcium, potassium:sodium antiporter activity
CP48_RS20930	COG0517	IMP dehydrogenase activity
CP48_RS20930	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CP48_RS20935	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CP48_RS20940	COG3117	lipopolysaccharide transmembrane transporter activity
CP48_RS20945	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CP48_RS20950	COG1137	ATPase activity
CP48_RS20955	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CP48_RS20960	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CP48_RS20975	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP48_RS20980	COG0515	serine threonine protein kinase
CP48_RS20990	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CP48_RS20995	COG2198	Histidine kinase
CP48_RS20995	COG5002	protein histidine kinase activity
CP48_RS20995	COG0784	Response regulator, receiver
CP48_RS21000	COG1242	4 iron, 4 sulfur cluster binding
CP48_RS21005	COG0067	glutamate synthase
CP48_RS21005	COG0070	glutamate synthase
CP48_RS21005	COG0069	glutamate synthase activity
CP48_RS21010	COG0493	'glutamate synthase
CP48_RS21015	COG4804	nuclease activity
CP48_RS21025	COG2731	YhcH YjgK YiaL family protein
CP48_RS21055	COG3069	C4-dicarboxylate transmembrane transporter activity
CP48_RS21060	COG2969	positive regulation of protein catabolic process
CP48_RS21065	COG0625	glutathione transferase activity
CP48_RS21080	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CP48_RS21085	COG3105	Protein conserved in bacteria
CP48_RS21090	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CP48_RS21095	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CP48_RS21115	COG2732	(Barnase) inhibitor
CP48_RS21135	COG0583	DNA-binding transcription factor activity
CP48_RS21140	COG0312	modulator of DNA gyrase
CP48_RS21145	COG3164	Protein of unknown function
CP48_RS21150	COG1530	ribonuclease E activity
CP48_RS21155	COG0424	maF-like protein
CP48_RS21160	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CP48_RS21165	COG1792	Involved in formation and maintenance of cell shape
CP48_RS21170	COG1077	Cell shape determining protein MreB Mrl
CP48_RS21180	COG2200	EAL domain
CP48_RS21180	COG2199	diguanylate cyclase activity
CP48_RS21185	COG0604	alcohol dehydrogenase
CP48_RS21205	COG0511	ligase activity, forming carbon-carbon bonds
CP48_RS21210	COG0439	Biotin carboxylase
CP48_RS21215	COG3924	membrane
CP48_RS21220	COG4145	pantothenate transmembrane transporter activity
CP48_RS21230	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CP48_RS21240	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CP48_RS21250	COG1309	transcriptional regulator
CP48_RS21255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CP48_RS21260	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CP48_RS21275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP48_RS21280	COG4597	amino acid ABC transporter
CP48_RS21285	COG0765	amino acid transport
CP48_RS21290	COG1126	abc transporter atp-binding protein
CP48_RS21330	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CP48_RS21350	COG0551	DNA topoisomerase type I activity
CP48_RS21360	COG0758	DNA mediated transformation
CP48_RS21380	COG0569	domain protein
CP48_RS21390	COG3036	rescue of stalled ribosome
CP48_RS21395	COG0789	Transcriptional regulator
CP48_RS21435	COG0201	protein transport
CP48_RS21525	COG0089	rRNA binding
CP48_RS21550	COG3267	Type II secretory pathway component ExeA
CP48_RS21550	COG3409	Peptidoglycan-binding domain 1 protein
CP48_RS21555	COG3031	protein transport across the cell outer membrane
CP48_RS21560	COG1450	Type ii and iii secretion system protein
CP48_RS21565	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CP48_RS21570	COG1459	type II secretion system
CP48_RS21575	COG2165	general secretion pathway protein
CP48_RS21580	COG2165	general secretion pathway protein
CP48_RS21585	COG2165	general secretion pathway protein
CP48_RS21590	COG4795	General secretion pathway protein
CP48_RS21595	COG3156	type II secretion system protein K
CP48_RS21600	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CP48_RS21605	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CP48_RS21615	COG2193	ferroxidase activity
CP48_RS21620	COG2906	2 iron, 2 sulfur cluster binding
CP48_RS21625	COG3979	chitinase
CP48_RS21665	COG2964	Protein conserved in bacteria
CP48_RS21670	COG0545	Peptidyl-prolyl cis-trans isomerase
CP48_RS21680	COG1047	Peptidyl-prolyl cis-trans
CP48_RS21685	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CP48_RS21700	COG0488	(ABC) transporter
CP48_RS21705	COG0429	hydrolase of the alpha beta-hydrolase fold
CP48_RS21715	COG3954	Phosphoribulokinase
CP48_RS21720	COG1765	OsmC-like protein
CP48_RS21730	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CP48_RS21735	COG1289	transmembrane transporter activity
CP48_RS21740	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CP48_RS21745	COG0512	Glutamine amidotransferase of anthranilate synthase
CP48_RS21750	COG2184	nucleotidyltransferase activity
CP48_RS21760	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CP48_RS21770	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CP48_RS21775	COG2146	nitrite reductase [NAD(P)H] activity
CP48_RS21780	COG2116	formate transmembrane transporter activity
CP48_RS21795	COG0531	amino acid
CP48_RS21800	COG2222	sugar isomerase
CP48_RS21805	COG1082	Xylose isomerase domain protein TIM barrel
CP48_RS21810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP48_RS21815	COG2188	Transcriptional regulator
CP48_RS21820	COG0626	cystathionine gamma-synthase activity
CP48_RS21835	COG1735	metal-dependent hydrolase with the TIM-barrel fold
CP48_RS21840	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CP48_RS21845	COG3457	Alanine racemase
CP48_RS21855	COG2188	Transcriptional regulator
CP48_RS21860	COG0180	Tryptophanyl-tRNA synthetase
CP48_RS21865	COG0546	phosphoglycolate phosphatase activity
CP48_RS21870	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CP48_RS21875	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CP48_RS21880	COG3266	domain, Protein
CP48_RS21895	COG4796	Type ii and iii secretion system protein
CP48_RS21910	COG3166	PFAM Fimbrial assembly family protein
CP48_RS21915	COG4972	Pilus assembly protein
CP48_RS21920	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CP48_RS21925	COG0494	nUDIX hydrolase
CP48_RS21935	COG1011	Hydrolase
CP48_RS21940	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CP48_RS21950	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CP48_RS21975	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CP48_RS21980	COG2183	response to ionizing radiation
CP48_RS21985	COG1918	ferrous iron import across plasma membrane
CP48_RS21990	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CP48_RS22000	COG5464	transposase or invertase
CP48_RS22020	COG2610	gluconate transmembrane transporter activity
CP48_RS22025	COG1640	4-alpha-glucanotransferase
CP48_RS22030	COG0058	SHG alpha-glucan phosphorylase activity
CP48_RS22045	COG1690	Belongs to the RtcB family
CP48_RS22050	COG4650	regulator
CP48_RS22055	COG1349	DNA-binding transcription factor activity
CP48_RS22070	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CP48_RS22075	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CP48_RS22080	COG0058	SHG alpha-glucan phosphorylase activity
CP48_RS22105	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CP48_RS22110	COG2095	MarC family integral membrane protein
CP48_RS22115	COG2610	gluconate transmembrane transporter activity
CP48_RS22120	COG3265	gluconokinase activity
CP48_RS22125	COG1609	Transcriptional regulator
CP48_RS22130	COG1741	Belongs to the pirin family
CP48_RS22135	COG0673	inositol 2-dehydrogenase activity
CP48_RS22140	COG1247	-acetyltransferase
CP48_RS22145	COG3157	Type VI secretion system effector, Hcp
CP48_RS22160	COG0405	Gamma-glutamyltransferase
CP48_RS22170	COG0584	glycerophosphoryl diester phosphodiesterase
CP48_RS22175	COG3842	ATPase activity
CP48_RS22185	COG1175	transmembrane transport
CP48_RS22190	COG1653	transport
CP48_RS22200	COG0410	ABC transporter
CP48_RS22205	COG0411	ABC transporter
CP48_RS22210	COG4177	L-phenylalanine transmembrane transporter activity
CP48_RS22215	COG0559	Belongs to the binding-protein-dependent transport system permease family
CP48_RS22220	COG0683	leucine binding
CP48_RS22225	COG0456	acetyltransferase
CP48_RS22235	COG0683	leucine binding
CP48_RS22240	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CP48_RS22245	COG2177	Part of the ABC transporter FtsEX involved in
CP48_RS22250	COG2884	Cell division ATP-binding protein ftsE
CP48_RS22255	COG0552	protein localization to endoplasmic reticulum
CP48_RS22260	COG0742	ribosomal rna small subunit methyltransferase
CP48_RS22265	COG3776	membrane
CP48_RS22275	COG3714	YhhN family
CP48_RS22290	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CP48_RS22305	COG0628	permease
CP48_RS22310	COG2091	lysine biosynthetic process via aminoadipic acid
CP48_RS22315	COG0747	negative chemotaxis
CP48_RS22320	COG0601	transmembrane transport
CP48_RS22325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP48_RS22330	COG0444	Belongs to the ABC transporter superfamily
CP48_RS22355	COG0842	Transport permease protein
CP48_RS22360	COG1129	ABC transporter
CP48_RS22360	COG0842	Transport permease protein
CP48_RS22365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CP48_RS22395	COG2081	HI0933 family
CP48_RS22400	COG0306	phosphate transporter
CP48_RS22410	COG0589	response to stress
CP48_RS22415	COG3104	oligopeptide transport
CP48_RS22425	COG0339	signal peptide processing
CP48_RS22430	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CP48_RS22435	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CP48_RS22450	COG0640	Transcriptional regulator
CP48_RS22455	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CP48_RS22460	COG1393	Belongs to the ArsC family
CP48_RS22470	COG3065	identical protein binding
CP48_RS22475	COG2197	response regulator
CP48_RS22480	COG1285	pathogenesis
CP48_RS22495	COG3247	response to pH
CP48_RS22500	COG2771	luxR family
CP48_RS22510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CP48_RS22515	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CP48_RS22520	COG2207	Transcriptional regulator
CP48_RS22530	COG0076	glutamate decarboxylase activity
CP48_RS22535	COG1858	cytochrome C peroxidase
CP48_RS22545	COG2197	response regulator
CP48_RS22550	COG0583	DNA-binding transcription factor activity
CP48_RS22555	COG1295	ribonuclease BN
CP48_RS22560	COG0477	Major facilitator Superfamily
CP48_RS22565	COG2982	Protein involved in outer membrane biogenesis
CP48_RS22570	COG2200	EAL domain
CP48_RS22580	COG3385	transposase activity
CP48_RS22590	COG0612	Peptidase, M16
CP48_RS22600	COG2200	EAL domain
CP48_RS22600	COG2199	diguanylate cyclase activity
CP48_RS22605	COG3118	belongs to the thioredoxin family
CP48_RS22605	COG0457	Tetratricopeptide repeat
CP48_RS22610	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CP48_RS22615	COG1215	transferase activity, transferring glycosyl groups
CP48_RS22625	COG1215	transferase activity, transferring glycosyl groups
CP48_RS22650	COG2194	sulfuric ester hydrolase activity
CP48_RS22675	COG0814	amino acid
CP48_RS22680	COG4608	Belongs to the ABC transporter superfamily
CP48_RS22685	COG0444	Belongs to the ABC transporter superfamily
CP48_RS22690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP48_RS22695	COG0601	transmembrane transport
CP48_RS22705	COG0747	negative chemotaxis
CP48_RS22725	COG2194	sulfuric ester hydrolase activity
CP48_RS22730	COG2223	nitrite transmembrane transporter activity
CP48_RS22735	COG5571	outer membrane autotransporter
CP48_RS22740	COG2818	Glycosylase
CP48_RS22745	COG0456	acetyltransferase
CP48_RS22750	COG0243	molybdopterin cofactor binding
CP48_RS22755	COG2885	chlorophyll binding
CP48_RS22770	COG2944	sequence-specific DNA binding
CP48_RS22775	COG1278	Cold shock
CP48_RS22785	COG2801	Transposase and inactivated derivatives
CP48_RS22790	COG2963	transposase activity
CP48_RS22810	COG3274	enterobacterial common antigen metabolic process
CP48_RS22815	COG4682	membrane
CP48_RS22820	COG4682	membrane
CP48_RS22825	COG1070	Carbohydrate kinase
CP48_RS22835	COG4213	ABC transporter substrate-binding protein
CP48_RS22840	COG1129	ABC transporter
CP48_RS22845	COG4214	carbohydrate transport
CP48_RS22850	COG1609	Transcriptional regulator
CP48_RS22850	COG2207	Transcriptional regulator
CP48_RS22855	COG2992	FlgJ-related protein
CP48_RS22860	COG0366	Alpha amylase catalytic
CP48_RS22865	COG3977	Valine--pyruvate aminotransferase
CP48_RS22875	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CP48_RS22880	COG1414	Transcriptional regulator
CP48_RS22890	COG2731	YhcH YjgK YiaL family protein
CP48_RS22895	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CP48_RS22900	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CP48_RS22905	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CP48_RS22910	COG1070	Carbohydrate kinase
CP48_RS22915	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CP48_RS22920	COG3623	hexulose-6-phosphate isomerase
CP48_RS22925	COG0235	Class ii aldolase
CP48_RS22930	COG3385	transposase activity
CP48_RS22935	COG0235	Class ii aldolase
CP48_RS22940	COG3713	MltA-interacting MipA family protein
CP48_RS22945	COG0583	DNA-binding transcription factor activity
CP48_RS22950	COG1566	PFAM secretion protein HlyD family protein
CP48_RS22965	COG1012	belongs to the aldehyde dehydrogenase family
CP48_RS22970	COG1454	alcohol dehydrogenase
CP48_RS22975	COG3276	selenocysteine insertion sequence binding
CP48_RS22985	COG0625	glutathione transferase activity
CP48_RS22990	COG3209	COG3209 Rhs family protein
CP48_RS22995	COG1413	lyase activity
CP48_RS23000	COG3209	COG3209 Rhs family protein
CP48_RS23005	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CP48_RS23015	COG1566	PFAM secretion protein HlyD family protein
CP48_RS23025	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP48_RS23025	COG2213	PTS system mannitol-specific
CP48_RS23035	COG3722	fumarate hydratase activity
CP48_RS23055	COG5295	Hep Hag repeat protein
CP48_RS23060	COG1620	l-lactate permease
CP48_RS23065	COG2186	Transcriptional regulator
CP48_RS23075	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CP48_RS23080	COG1045	serine acetyltransferase
CP48_RS23095	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CP48_RS23100	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CP48_RS23110	COG4942	peptidase
CP48_RS23115	COG2861	carbohydrate metabolic process
CP48_RS23120	COG1216	Glycosyl transferase, family 2
CP48_RS23130	COG0156	8-amino-7-oxononanoate synthase activity
CP48_RS23140	COG0859	PFAM glycosyl transferase family 9
CP48_RS23145	COG0859	PFAM glycosyl transferase family 9
CP48_RS23160	COG1442	glycosyl transferase family 8
CP48_RS23165	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CP48_RS23180	COG0515	serine threonine protein kinase
CP48_RS23185	COG0438	transferase activity, transferring glycosyl groups
CP48_RS23190	COG0859	PFAM glycosyl transferase family 9
CP48_RS23195	COG1519	Transferase
CP48_RS23225	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CP48_RS23250	COG1561	YicC-like family, N-terminal region
CP48_RS23260	COG2860	membrane
CP48_RS23270	COG0194	GDP metabolic process
CP48_RS23280	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CP48_RS23285	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CP48_RS23290	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CP48_RS23295	COG0786	glutamate:sodium symporter activity
CP48_RS23300	COG2233	PERMEase
CP48_RS23305	COG2982	Protein involved in outer membrane biogenesis
CP48_RS23310	COG1501	Belongs to the glycosyl hydrolase 31 family
CP48_RS23315	COG2211	Major facilitator Superfamily
CP48_RS23325	COG0582	viral genome integration into host DNA
CP48_RS23385	COG2814	Major facilitator Superfamily
CP48_RS23390	COG0697	spore germination
CP48_RS23395	COG1464	Belongs to the NlpA lipoprotein family
CP48_RS23420	COG2252	PERMEase
CP48_RS23430	COG2271	Major facilitator Superfamily
CP48_RS23435	COG2271	Major facilitator Superfamily
CP48_RS23440	COG3851	Histidine kinase
CP48_RS23445	COG2197	response regulator
CP48_RS23450	COG0440	acetolactate synthase activity
CP48_RS23455	COG0028	Belongs to the TPP enzyme family
CP48_RS23475	COG2814	Major facilitator Superfamily
CP48_RS23480	COG0641	radical SAM
CP48_RS23490	COG2149	membrane
CP48_RS23500	COG3119	arylsulfatase activity
CP48_RS23505	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CP48_RS23510	COG2207	Transcriptional regulator
CP48_RS23545	COG5645	(Lipo)protein
CP48_RS23550	COG0823	Involved in the tonB-independent uptake of proteins
CP48_RS23555	COG0644	oxidoreductase
CP48_RS23560	COG2271	Major facilitator Superfamily
CP48_RS23570	COG0800	Aldolase
CP48_RS23575	COG3734	2-keto-3-deoxy-galactonokinase
CP48_RS23580	COG2186	Transcriptional regulator
CP48_RS23590	COG0561	phosphatase activity
CP48_RS23595	COG3753	Protein conserved in bacteria
CP48_RS23605	COG0187	DNA topoisomerase II activity
CP48_RS23615	COG0592	DNA-directed DNA polymerase activity
CP48_RS23660	COG0814	amino acid
CP48_RS23675	COG2091	lysine biosynthetic process via aminoadipic acid
CP48_RS23680	COG0431	NADPH-dependent FMN reductase
CP48_RS23685	COG2252	PERMEase
CP48_RS23690	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CP48_RS23700	COG3196	Protein conserved in bacteria
CP48_RS23705	COG0363	glucosamine-6-phosphate deaminase activity
CP48_RS23710	COG2382	esterase
CP48_RS23725	COG2723	6-phospho-beta-galactosidase activity
CP48_RS23730	COG1263	PTS System
CP48_RS23730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CP48_RS23730	COG2190	(PTS) system
CP48_RS23735	COG3711	transcriptional antiterminator
CP48_RS23740	COG0704	Plays a role in the regulation of phosphate uptake
CP48_RS23745	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CP48_RS23750	COG0581	inorganic phosphate transmembrane transporter activity
CP48_RS23755	COG0573	inorganic phosphate transmembrane transporter activity
CP48_RS23760	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CP48_RS23785	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CP48_RS23835	COG3312	ion transport
CP48_RS23850	COG0716	FMN binding
CP48_RS23855	COG1522	sequence-specific DNA binding
CP48_RS23885	COG1129	ABC transporter
CP48_RS23890	COG1172	Belongs to the binding-protein-dependent transport system permease family
CP48_RS23895	COG1879	ABC-type sugar transport system periplasmic component
CP48_RS23900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP48_RS23905	COG1609	Transcriptional regulator
CP48_RS23910	COG0477	Major facilitator Superfamily
CP48_RS23915	COG2186	Transcriptional regulator
CP48_RS23955	COG3085	chromosome segregation
CP48_RS23960	COG0606	chelatase, subunit chli
CP48_RS23975	COG3978	acetolactate synthase activity
CP48_RS23980	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CP48_RS23990	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CP48_RS23995	COG0583	DNA-binding transcription factor activity
CP48_RS24005	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CP48_RS24010	COG3692	DNA binding
CP48_RS24015	COG0210	DNA helicase
CP48_RS24030	COG3118	belongs to the thioredoxin family
CP48_RS24040	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CP48_RS24050	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CP48_RS24055	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CP48_RS24060	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CP48_RS24065	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CP48_RS24070	COG1088	dTDP-glucose 4,6-dehydratase activity
CP48_RS24075	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CP48_RS24080	COG0456	acetyltransferase
CP48_RS24085	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CP48_RS24090	COG2244	polysaccharide biosynthetic process
CP48_RS24110	COG1113	amino acid transport
CP48_RS24135	COG0641	radical SAM
CP48_RS24140	COG3119	arylsulfatase activity
CP48_RS24145	COG3071	HemY protein
CP48_RS24150	COG2959	enzyme of heme biosynthesis
CP48_RS24155	COG1587	Uroporphyrinogen-III synthase
CP48_RS24165	COG3072	Adenylate cyclase
CP48_RS24175	COG5567	small periplasmic lipoprotein
CP48_RS24185	COG3159	Protein conserved in bacteria
CP48_RS24195	COG1011	Hydrolase
CP48_RS24200	COG0210	DNA helicase
CP48_RS24205	COG3698	Phosphodiester glycosidase
CP48_RS24215	COG0598	Magnesium transport protein CorA
CP48_RS24250	COG2050	protein possibly involved in aromatic compounds catabolism
CP48_RS24255	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
CP48_RS24260	COG0514	ATP-dependent DNA helicase (RecQ)
CP48_RS24265	COG1280	lysine exporter protein (LysE YggA)
CP48_RS24270	COG1280	lysine exporter protein (LysE YggA)
CP48_RS24275	COG2267	carboxylic ester hydrolase activity
CP48_RS24280	COG0561	phosphatase activity
CP48_RS24285	COG0697	spore germination
CP48_RS24290	COG0583	DNA-binding transcription factor activity
CP48_RS24300	COG0412	Dienelactone hydrolase
CP48_RS24305	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CP48_RS24310	COG1322	Protein conserved in bacteria
CP48_RS24320	COG3165	ubiquinone biosynthetic process from chorismate
CP48_RS24330	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CP48_RS24335	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CP48_RS24340	COG0805	protein transport
CP48_RS24345	COG0084	hydrolase, TatD family'
CP48_RS24350	COG0250	Participates in transcription elongation, termination and antitermination
CP48_RS24355	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CP48_RS24360	COG0543	2 iron, 2 sulfur cluster binding
CP48_RS24380	COG1739	Uncharacterized protein family UPF0029
CP48_RS24385	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CP48_RS24390	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CP48_RS24420	COG1763	Mo-molybdopterin cofactor biosynthetic process
CP48_RS24425	COG0746	molybdenum cofactor guanylyltransferase activity
CP48_RS24430	COG3084	Protein conserved in bacteria
CP48_RS24435	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CP48_RS24440	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CP48_RS24445	COG5339	Protein conserved in bacteria
CP48_RS24450	COG0204	Acyl-transferase
CP48_RS24465	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CP48_RS24465	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CP48_RS24480	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CP48_RS24490	COG2204	response regulator
CP48_RS24495	COG3852	Histidine kinase
CP48_RS24500	COG0174	glutamine synthetase
CP48_RS24510	COG1217	gtp-binding protein TYPA
CP48_RS24515	COG2188	Transcriptional regulator
CP48_RS24520	COG1082	Xylose isomerase domain protein TIM barrel
CP48_RS24525	COG2271	Major facilitator Superfamily
CP48_RS24530	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CP48_RS24535	COG2211	Major facilitator Superfamily
CP48_RS24545	COG1501	Belongs to the glycosyl hydrolase 31 family
CP48_RS24550	COG2017	converts alpha-aldose to the beta-anomer
CP48_RS24555	COG2942	2-epimerase
CP48_RS24560	COG3684	Belongs to the aldolase LacD family
CP48_RS24565	COG2084	Dehydrogenase
CP48_RS24570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP48_RS24575	COG1349	DNA-binding transcription factor activity
CP48_RS24580	COG1011	Hydrolase
CP48_RS24595	COG0456	acetyltransferase
CP48_RS24600	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CP48_RS24605	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CP48_RS24620	COG2864	formate dehydrogenase
CP48_RS24625	COG0437	4 iron, 4 sulfur cluster binding
CP48_RS24630	COG0243	molybdopterin cofactor binding
CP48_RS24630	COG3383	formate dehydrogenase (NAD+) activity
CP48_RS24635	COG3383	formate dehydrogenase (NAD+) activity
CP48_RS24635	COG0243	molybdopterin cofactor binding
CP48_RS24650	COG3711	transcriptional antiterminator
CP48_RS24650	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP48_RS24655	COG1363	Peptidase, m42
CP48_RS24660	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CP48_RS24660	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CP48_RS24665	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP48_RS24710	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CP48_RS24725	COG2258	MOSC domain
CP48_RS24730	COG2205	protein histidine kinase activity
CP48_RS24735	COG0745	RESPONSE REGULATOR receiver
CP48_RS24740	COG3678	ATP-independent chaperone mediated protein folding
CP48_RS24755	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CP48_RS24775	COG3152	Membrane
CP48_RS24780	COG3691	Protein conserved in bacteria
CP48_RS24785	COG0589	response to stress
CP48_RS24790	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CP48_RS24795	COG1494	fructose-1,6-bisphosphatase
CP48_RS24805	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CP48_RS24820	COG1575	Belongs to the MenA family. Type 1 subfamily
CP48_RS24835	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CP48_RS24840	COG1609	Transcriptional regulator
CP48_RS24845	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CP48_RS24855	COG3209	COG3209 Rhs family protein
CP48_RS24860	COG3385	transposase activity
CP48_RS24865	COG3209	COG3209 Rhs family protein
CP48_RS24895	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
CP48_RS24905	COG0626	cystathionine gamma-synthase activity
CP48_RS24910	COG0460	homoserine dehydrogenase
CP48_RS24910	COG0527	aspartate kinase activity
CP48_RS24920	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CP48_RS24930	COG0697	spore germination
CP48_RS24935	COG3738	Protein conserved in bacteria
CP48_RS24945	COG0371	Dehydrogenase
CP48_RS24950	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CP48_RS24955	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP48_RS24955	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP48_RS24955	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CP48_RS24960	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CP48_RS24965	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CP48_RS24970	COG1882	Formate acetyltransferase
CP48_RS24975	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CP48_RS24980	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CP48_RS24985	COG2207	Transcriptional regulator
CP48_RS24990	COG2194	sulfuric ester hydrolase activity
CP48_RS25005	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CP48_RS25020	COG0583	DNA-binding transcription factor activity
CP48_RS25045	COG4206	TonB-dependent receptor
CP48_RS25080	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CP48_RS25080	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CP48_RS25120	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CP48_RS25125	COG0250	Participates in transcription elongation, termination and antitermination
CP48_RS25165	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CP48_RS25175	COG2104	thiamine diphosphate biosynthetic process
CP48_RS25180	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CP48_RS25215	COG3068	Protein conserved in bacteria
CP48_RS25230	COG3678	ATP-independent chaperone mediated protein folding
CP48_RS25235	COG4191	Histidine kinase
CP48_RS25240	COG2204	response regulator
CP48_RS25245	COG0151	Belongs to the GarS family
CP48_RS25280	COG0456	acetyltransferase
CP48_RS25290	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CP48_RS25295	COG2224	Isocitrate lyase
CP48_RS25315	COG1414	Transcriptional regulator
CP48_RS25320	COG0646	methionine synthase
CP48_RS25320	COG1410	methionine synthase
CP48_RS25325	COG1283	sodium-dependent phosphate transmembrane transporter activity
CP48_RS25335	COG1187	pseudouridine synthase activity
CP48_RS25345	COG0527	aspartate kinase activity
CP48_RS25370	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP48_RS25390	COG0477	Major facilitator Superfamily
CP48_RS25390	COG2814	Major facilitator Superfamily
CP48_RS25395	COG3833	ABC-type maltose transport systems, permease component
CP48_RS25400	COG1175	transmembrane transport
CP48_RS25405	COG2182	Extracellular solute-binding protein
CP48_RS25415	COG3842	ATPase activity
CP48_RS25435	COG1357	PFAM Pentapeptide repeats (8 copies)
CP48_RS25455	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CP48_RS25465	COG0534	Mate efflux family protein
CP48_RS25470	COG3237	CsbD-like
CP48_RS25475	COG0735	belongs to the Fur family
CP48_RS25490	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CP48_RS25500	COG0604	alcohol dehydrogenase
CP48_RS25505	COG0305	Participates in initiation and elongation during chromosome replication
CP48_RS25510	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CP48_RS25515	COG1448	Aminotransferase
CP48_RS25525	COG3700	Belongs to the class B bacterial acid phosphatase family
CP48_RS25530	COG0432	Pfam Uncharacterised protein family UPF0047
CP48_RS25535	COG2315	Protein conserved in bacteria
CP48_RS25540	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CP48_RS25545	COG0629	single-stranded DNA binding
CP48_RS25555	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CP48_RS25560	COG2207	Transcriptional regulator
CP48_RS25565	COG0789	Transcriptional regulator
CP48_RS25570	COG2252	PERMEase
CP48_RS25575	COG0025	NhaP-type Na H and K H
CP48_RS25580	COG1357	PFAM Pentapeptide repeats (8 copies)
CP48_RS25590	COG3162	membrane
CP48_RS25595	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CP48_RS25605	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CP48_RS25610	COG0437	4 iron, 4 sulfur cluster binding
CP48_RS25615	COG3301	Polysulphide reductase, NrfD
CP48_RS25620	COG1138	Cytochrome C-type biogenesis protein
CP48_RS25625	COG3088	subunit of a heme lyase
CP48_RS25630	COG4235	cytochrome complex assembly
CP48_RS25635	COG1301	dicarboxylic acid transport
CP48_RS25640	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CP48_RS25645	COG3383	formate dehydrogenase (NAD+) activity
CP48_RS25650	COG3383	formate dehydrogenase (NAD+) activity
CP48_RS25660	COG1289	transmembrane transporter activity
CP48_RS25665	COG1566	PFAM secretion protein HlyD family protein
CP48_RS25675	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CP48_RS25680	COG0698	ribose 5-phosphate isomerase
CP48_RS25690	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CP48_RS25695	COG0456	acetyltransferase
CP48_RS25700	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CP48_RS25705	COG3454	Phosphonate metabolism
CP48_RS25710	COG4778	phosphonate C-P lyase system protein PhnL
CP48_RS25715	COG4107	phosphonate C-P lyase system protein PhnK
CP48_RS25720	COG3627	carbon phosphorus lyase activity
CP48_RS25725	COG3626	phosphonate metabolism
CP48_RS25730	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CP48_RS25735	COG3624	Phosphonate C-P lyase system protein PhnG
CP48_RS25740	COG2188	Transcriptional regulator
CP48_RS25745	COG3639	organic phosphonate transmembrane transporter activity
CP48_RS25750	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CP48_RS25760	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CP48_RS25765	COG2824	Alkylphosphonate utilization operon protein PhnA
CP48_RS25770	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CP48_RS25780	COG0477	Major facilitator Superfamily
CP48_RS25790	COG0642	Histidine kinase
CP48_RS25795	COG0745	RESPONSE REGULATOR receiver
CP48_RS25800	COG2194	sulfuric ester hydrolase activity
CP48_RS25805	COG0531	amino acid
CP48_RS25810	COG2207	Transcriptional regulator
CP48_RS25815	COG1982	Orn Lys Arg decarboxylase major
CP48_RS25820	COG2169	Transcriptional regulator
CP48_RS25830	COG1486	melibiose metabolic process
CP48_RS25835	COG2211	Major facilitator Superfamily
CP48_RS25840	COG3647	Membrane
CP48_RS25845	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CP48_RS25845	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CP48_RS25850	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CP48_RS25860	COG4565	transcriptional regulatory protein
CP48_RS25865	COG3290	protein histidine kinase activity
CP48_RS25870	COG3592	Divergent 4Fe-4S mono-cluster
CP48_RS25875	COG2388	GCN5-related N-acetyl-transferase
CP48_RS25890	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CP48_RS25895	COG3104	oligopeptide transport
CP48_RS25900	COG1982	Orn Lys Arg decarboxylase major
CP48_RS25905	COG0531	amino acid
CP48_RS25910	COG3710	Transcriptional regulator
CP48_RS25925	COG1309	transcriptional regulator
CP48_RS25940	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CP48_RS25945	COG1027	Aspartate ammonia-lyase
CP48_RS25950	COG3030	protein affecting phage T7 exclusion by the F plasmid
CP48_RS25955	COG0531	amino acid
CP48_RS25980	COG1509	lysine 2,3-aminomutase activity
CP48_RS25990	COG5510	response to toxic substance
CP48_RS25995	COG5510	response to toxic substance
CP48_RS26000	COG2076	Multidrug Resistance protein
CP48_RS26005	COG3040	lipid binding
CP48_RS26010	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CP48_RS26025	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CP48_RS26030	COG1053	succinate dehydrogenase
CP48_RS26040	COG0531	amino acid
CP48_RS26045	COG3264	Mechanosensitive ion channel
CP48_RS26045	COG1511	domain protein
CP48_RS26080	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CP48_RS26085	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CP48_RS26085	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CP48_RS26090	COG0802	atpase or kinase
CP48_RS26095	COG0860	N-Acetylmuramoyl-L-alanine amidase
CP48_RS26115	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CP48_RS26125	COG0330	HflC and HflK could
CP48_RS26130	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CP48_RS26145	COG0557	exoribonuclease II activity
CP48_RS26150	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CP48_RS26155	COG1414	Transcriptional regulator
CP48_RS26160	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CP48_RS26165	COG2271	Major facilitator Superfamily
CP48_RS26170	COG2721	sulfolactate sulfo-lyase activity
CP48_RS26175	COG3789	protein conserved in bacteria
CP48_RS26180	COG1842	Phage shock protein A
CP48_RS26190	COG3766	membrane
CP48_RS26195	COG5463	Belongs to the UPF0441 family
CP48_RS26200	COG0754	glutathionylspermidine amidase activity
CP48_RS26205	COG1960	acyl-CoA dehydrogenase activity
CP48_RS26215	COG3650	response to hydrogen peroxide
CP48_RS26220	COG1073	alpha beta
CP48_RS26235	COG3037	sugar-specific permease SgaT UlaA
CP48_RS26240	COG3414	Phosphotransferase system galactitol-specific IIB component
CP48_RS26285	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CP48_RS26295	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CP48_RS26305	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CP48_RS26310	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CP48_RS26315	COG4670	ketone body catabolic process
CP48_RS26320	COG1024	Enoyl-CoA hydratase
CP48_RS26335	COG1309	transcriptional regulator
CP48_RS26340	COG3061	Opacity-associated protein A
CP48_RS26345	COG0545	Peptidyl-prolyl cis-trans isomerase
CP48_RS26350	COG1113	amino acid transport
CP48_RS26360	COG0697	spore germination
CP48_RS26365	COG0702	epimerase
CP48_RS26370	COG1733	regulation of RNA biosynthetic process
CP48_RS26375	COG0737	Belongs to the 5'-nucleotidase family
CP48_RS26380	COG1218	3'(2'),5'-bisphosphate nucleotidase
CP48_RS26385	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CP48_RS26395	COG1253	flavin adenine dinucleotide binding
CP48_RS26410	COG0729	surface antigen
CP48_RS26415	COG2911	Protein conserved in bacteria
CP48_RS26420	COG2105	PFAM AIG2 family protein
CP48_RS26425	COG2336	PFAM SpoVT AbrB
CP48_RS26430	COG2337	Toxic component of a toxin-antitoxin (TA) module
CP48_RS26435	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CP48_RS26440	COG1879	ABC-type sugar transport system periplasmic component
CP48_RS26445	COG1129	ABC transporter
CP48_RS26450	COG1172	Belongs to the binding-protein-dependent transport system permease family
CP48_RS26455	COG1172	Belongs to the binding-protein-dependent transport system permease family
CP48_RS26465	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CP48_RS26475	COG0312	modulator of DNA gyrase
CP48_RS26480	COG3783	Cytochrome b(562)
CP48_RS26485	COG0602	queuosine metabolic process
CP48_RS26490	COG1328	CTP reductase activity
CP48_RS26495	COG0366	Alpha amylase catalytic
CP48_RS26500	COG1263	PTS System
CP48_RS26500	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CP48_RS26505	COG1609	Transcriptional regulator
CP48_RS26510	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CP48_RS26515	COG0251	oxidation-reduction process
CP48_RS26540	COG0251	oxidation-reduction process
CP48_RS26545	COG1028	Short-chain dehydrogenase reductase Sdr
CP48_RS26550	COG1309	transcriptional regulator
CP48_RS26555	COG2731	YhcH YjgK YiaL family protein
CP48_RS26570	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
CP48_RS26575	COG0456	acetyltransferase
CP48_RS26580	COG4269	membrane
CP48_RS26585	COG0525	valine-tRNA ligase activity
CP48_RS26590	COG2927	DNA polymerase III (CHI subunit)
CP48_RS26600	COG0795	lipopolysaccharide-transporting ATPase activity
CP48_RS26605	COG0795	lipopolysaccharide-transporting ATPase activity
CP48_RS26610	COG0433	COG0433 Predicted ATPase
CP48_RS26615	COG0433	COG0433 Predicted ATPase
CP48_RS26620	COG1609	Transcriptional regulator
CP48_RS26625	COG2610	gluconate transmembrane transporter activity
CP48_RS26630	COG1028	Short-chain dehydrogenase reductase Sdr
CP48_RS26635	COG1063	alcohol dehydrogenase
CP48_RS26640	COG3265	gluconokinase activity
CP48_RS26645	COG1064	alcohol dehydrogenase
CP48_RS26655	COG0582	viral genome integration into host DNA
CP48_RS26665	COG2194	sulfuric ester hydrolase activity
CP48_RS26685	COG3385	transposase activity
CP48_RS26695	COG2814	Major facilitator Superfamily
CP48_RS26700	COG0673	inositol 2-dehydrogenase activity
CP48_RS26720	COG3188	usher protein
CP48_RS26725	COG3539	Fimbrial protein
CP48_RS26730	COG3539	Fimbrial protein
CP48_RS26740	COG2610	gluconate transmembrane transporter activity
CP48_RS26755	COG0246	Mannitol dehydrogenase
CP48_RS26765	COG2186	Transcriptional regulator
CP48_RS26790	COG0583	DNA-binding transcription factor activity
CP48_RS26795	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CP48_RS26800	COG0700	Nucleoside recognition
CP48_RS26805	COG3366	ferrous iron transmembrane transporter activity
CP48_RS26810	COG3385	transposase activity
CP48_RS26815	COG3366	ferrous iron transmembrane transporter activity
CP48_RS26825	COG0477	Major facilitator Superfamily
CP48_RS26840	COG1924	4 iron, 4 sulfur cluster binding
CP48_RS26845	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
CP48_RS26855	COG2814	Major facilitator Superfamily
CP48_RS26865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP48_RS26870	COG5457	Domain of unknown function (DUF1127)
CP48_RS26880	COG3385	transposase activity
CP48_RS26895	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CP48_RS26900	COG0732	type I restriction modification DNA specificity domain
CP48_RS26905	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CP48_RS26910	COG1715	Restriction endonuclease
CP48_RS26925	COG0523	cobalamin synthesis protein
CP48_RS26930	COG2879	small protein
CP48_RS26935	COG1966	Carbon starvation protein
CP48_RS26945	COG0840	transmembrane signaling receptor activity
CP48_RS26950	COG2271	Major facilitator Superfamily
CP48_RS26955	COG1802	Transcriptional regulator
CP48_RS26960	COG1063	alcohol dehydrogenase
CP48_RS26975	COG1484	DNA-dependent DNA replication
CP48_RS26990	COG2966	Psort location CytoplasmicMembrane, score
CP48_RS26995	COG2197	response regulator
CP48_RS27000	COG2197	response regulator
CP48_RS27005	COG4114	ferric iron reductase
CP48_RS27040	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CP48_RS27045	COG0456	acetyltransferase
CP48_RS27050	COG1011	Hydrolase
CP48_RS27060	COG2131	deaminase
CP48_RS27090	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CP48_RS27095	COG5532	Uncharacterized conserved protein (DUF2303)
CP48_RS27110	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CP48_RS27115	COG4197	protein conserved in bacteria, prophage-related
CP48_RS27125	COG3646	Phage regulatory protein
CP48_RS27145	COG5301	cellulose 1,4-beta-cellobiosidase activity
CP48_RS27155	COG5301	cellulose 1,4-beta-cellobiosidase activity
CP48_RS27200	COG3436	PFAM IS66 Orf2 family protein
CP48_RS27205	COG4372	Transposase
CP48_RS27250	COG4397	Mu-like prophage major head subunit gpT
CP48_RS27270	COG2369	cell adhesion
CP48_RS27275	COG4383	Mu-like prophage protein gp29
CP48_RS27390	COG2842	Transposition protein
CP48_RS27410	COG1846	Transcriptional regulator
CP48_RS27425	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CP48_RS27440	COG1403	HNH endonuclease
CP48_RS27445	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CP48_RS27450	COG0484	heat shock protein binding
CP48_RS27505	COG3772	lysozyme
CP48_RS27535	COG4220	transposase activity
CP48_RS27640	COG5301	cellulose 1,4-beta-cellobiosidase activity
CP48_RS27660	COG2823	Periplasmic or secreted lipoprotein
CP48_RS27670	COG4667	esterase of the alpha-beta hydrolase superfamily
CP48_RS27675	COG0084	hydrolase, TatD family'
CP48_RS27680	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CP48_RS27685	COG1328	CTP reductase activity
CP48_RS27715	COG3550	peptidyl-serine autophosphorylation
CP48_RS27725	COG3726	membrane protein affecting hemolysin expression
CP48_RS27730	COG0560	Phosphoserine phosphatase
CP48_RS27735	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CP48_RS27740	COG1056	cytidyltransferase-related domain
CP48_RS27740	COG3172	ATPase kinase involved in NAD metabolism
CP48_RS27750	COG0488	(ABC) transporter
CP48_RS27755	COG0741	lytic transglycosylase activity
CP48_RS27775	COG3708	Transcriptional regulator
CP48_RS27775	COG2207	Transcriptional regulator
CP48_RS27780	COG3045	CreA protein
CP48_RS27785	COG0745	RESPONSE REGULATOR receiver
CP48_RS27790	COG2205	protein histidine kinase activity
CP48_RS27795	COG4452	Inner membrane protein CreD
CP48_RS27800	COG0745	RESPONSE REGULATOR receiver
CP48_RS27810	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA