locus-tag	class	description
C9E41_RS00015	COG3312	ion transport
C9E41_RS00055	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C9E41_RS00065	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C9E41_RS00090	COG3539	Fimbrial protein
C9E41_RS00100	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C9E41_RS00105	COG0573	inorganic phosphate transmembrane transporter activity
C9E41_RS00110	COG0581	inorganic phosphate transmembrane transporter activity
C9E41_RS00115	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C9E41_RS00120	COG0704	Plays a role in the regulation of phosphate uptake
C9E41_RS00160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C9E41_RS00165	COG2252	PERMEase
C9E41_RS00170	COG0431	NADPH-dependent FMN reductase
C9E41_RS00175	COG2091	lysine biosynthetic process via aminoadipic acid
C9E41_RS00190	COG0814	amino acid
C9E41_RS00245	COG0592	DNA-directed DNA polymerase activity
C9E41_RS00255	COG0187	DNA topoisomerase II activity
C9E41_RS00260	COG3753	Protein conserved in bacteria
C9E41_RS00265	COG0561	phosphatase activity
C9E41_RS00275	COG0644	oxidoreductase
C9E41_RS00280	COG0823	Involved in the tonB-independent uptake of proteins
C9E41_RS00285	COG5645	(Lipo)protein
C9E41_RS00305	COG2188	Transcriptional regulator
C9E41_RS00320	COG2207	Transcriptional regulator
C9E41_RS00325	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C9E41_RS00330	COG3119	arylsulfatase activity
C9E41_RS00340	COG2149	membrane
C9E41_RS00350	COG0641	radical SAM
C9E41_RS00355	COG2814	Major facilitator Superfamily
C9E41_RS00370	COG0028	Belongs to the TPP enzyme family
C9E41_RS00375	COG0440	acetolactate synthase activity
C9E41_RS00395	COG2197	response regulator
C9E41_RS00400	COG3851	Histidine kinase
C9E41_RS00405	COG2271	Major facilitator Superfamily
C9E41_RS00410	COG2271	Major facilitator Superfamily
C9E41_RS00445	COG2814	Major facilitator Superfamily
C9E41_RS00455	COG1464	Belongs to the NlpA lipoprotein family
C9E41_RS00460	COG0697	spore germination
C9E41_RS00630	COG5492	domain, Protein
C9E41_RS00690	COG4372	Transposase
C9E41_RS00695	COG3436	PFAM IS66 Orf2 family protein
C9E41_RS00735	COG0582	viral genome integration into host DNA
C9E41_RS00745	COG2211	Major facilitator Superfamily
C9E41_RS00750	COG1501	Belongs to the glycosyl hydrolase 31 family
C9E41_RS00755	COG2982	Protein involved in outer membrane biogenesis
C9E41_RS00760	COG2233	PERMEase
C9E41_RS00765	COG0786	glutamate:sodium symporter activity
C9E41_RS00775	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C9E41_RS00780	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C9E41_RS00785	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C9E41_RS00795	COG0194	GDP metabolic process
C9E41_RS00805	COG2860	membrane
C9E41_RS00810	COG3645	SOS response
C9E41_RS00815	COG1561	YicC-like family, N-terminal region
C9E41_RS00840	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C9E41_RS00870	COG1519	Transferase
C9E41_RS00875	COG0859	PFAM glycosyl transferase family 9
C9E41_RS00880	COG0438	transferase activity, transferring glycosyl groups
C9E41_RS00885	COG0515	serine threonine protein kinase
C9E41_RS00895	COG3642	lipopolysaccharide core region biosynthetic process
C9E41_RS00915	COG0859	PFAM glycosyl transferase family 9
C9E41_RS00920	COG0859	PFAM glycosyl transferase family 9
C9E41_RS00935	COG0156	8-amino-7-oxononanoate synthase activity
C9E41_RS00945	COG1216	Glycosyl transferase, family 2
C9E41_RS00950	COG2861	carbohydrate metabolic process
C9E41_RS00955	COG4942	peptidase
C9E41_RS00965	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C9E41_RS00970	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C9E41_RS00985	COG1045	serine acetyltransferase
C9E41_RS00990	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C9E41_RS01000	COG2186	Transcriptional regulator
C9E41_RS01005	COG1620	l-lactate permease
C9E41_RS01010	COG5295	Hep Hag repeat protein
C9E41_RS01035	COG3722	fumarate hydratase activity
C9E41_RS01045	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9E41_RS01045	COG2213	PTS system mannitol-specific
C9E41_RS01055	COG1566	PFAM secretion protein HlyD family protein
C9E41_RS01075	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C9E41_RS01080	COG3209	COG3209 Rhs family protein
C9E41_RS01085	COG0625	glutathione transferase activity
C9E41_RS01095	COG3276	selenocysteine insertion sequence binding
C9E41_RS01100	COG1454	alcohol dehydrogenase
C9E41_RS01110	COG1012	belongs to the aldehyde dehydrogenase family
C9E41_RS01125	COG1566	PFAM secretion protein HlyD family protein
C9E41_RS01130	COG0583	DNA-binding transcription factor activity
C9E41_RS01135	COG3713	MltA-interacting MipA family protein
C9E41_RS01145	COG2211	Major facilitator Superfamily
C9E41_RS01155	COG1414	Transcriptional regulator
C9E41_RS01160	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C9E41_RS01165	COG3977	Valine--pyruvate aminotransferase
C9E41_RS01170	COG0366	Alpha amylase catalytic
C9E41_RS01175	COG2992	FlgJ-related protein
C9E41_RS01180	COG2207	Transcriptional regulator
C9E41_RS01180	COG1609	Transcriptional regulator
C9E41_RS01185	COG4214	carbohydrate transport
C9E41_RS01195	COG4213	ABC transporter substrate-binding protein
C9E41_RS01205	COG1070	Carbohydrate kinase
C9E41_RS01210	COG4682	membrane
C9E41_RS01215	COG4682	membrane
C9E41_RS01220	COG3274	enterobacterial common antigen metabolic process
C9E41_RS01245	COG1278	Cold shock
C9E41_RS01250	COG2944	sequence-specific DNA binding
C9E41_RS01265	COG2885	chlorophyll binding
C9E41_RS01270	COG0243	molybdopterin cofactor binding
C9E41_RS01275	COG0456	acetyltransferase
C9E41_RS01280	COG2818	Glycosylase
C9E41_RS01285	COG5571	outer membrane autotransporter
C9E41_RS01290	COG2223	nitrite transmembrane transporter activity
C9E41_RS01295	COG3539	Fimbrial protein
C9E41_RS01300	COG3121	Chaperone
C9E41_RS01310	COG3539	Fimbrial protein
C9E41_RS01315	COG3539	Fimbrial protein
C9E41_RS01320	COG2194	sulfuric ester hydrolase activity
C9E41_RS01330	COG0747	negative chemotaxis
C9E41_RS01340	COG0601	transmembrane transport
C9E41_RS01345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C9E41_RS01350	COG0444	Belongs to the ABC transporter superfamily
C9E41_RS01355	COG4608	Belongs to the ABC transporter superfamily
C9E41_RS01360	COG0814	amino acid
C9E41_RS01375	COG2194	sulfuric ester hydrolase activity
C9E41_RS01405	COG1215	transferase activity, transferring glycosyl groups
C9E41_RS01410	COG1215	transferase activity, transferring glycosyl groups
C9E41_RS01415	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
C9E41_RS01425	COG2199	diguanylate cyclase activity
C9E41_RS01425	COG2200	EAL domain
C9E41_RS01435	COG0612	Peptidase, M16
C9E41_RS01445	COG2200	EAL domain
C9E41_RS01450	COG2982	Protein involved in outer membrane biogenesis
C9E41_RS01455	COG0477	Major facilitator Superfamily
C9E41_RS01460	COG1295	ribonuclease BN
C9E41_RS01465	COG0583	DNA-binding transcription factor activity
C9E41_RS01470	COG2197	response regulator
C9E41_RS01480	COG1858	cytochrome C peroxidase
C9E41_RS01485	COG0076	glutamate decarboxylase activity
C9E41_RS01490	COG2207	Transcriptional regulator
C9E41_RS01495	COG2207	Transcriptional regulator
C9E41_RS01500	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C9E41_RS01505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C9E41_RS01515	COG2771	luxR family
C9E41_RS01520	COG3247	response to pH
C9E41_RS01535	COG1285	pathogenesis
C9E41_RS01540	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
C9E41_RS01545	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C9E41_RS01555	COG3721	Heme iron utilization protein
C9E41_RS01565	COG4558	Periplasmic binding protein
C9E41_RS01575	COG4771	TonB-dependent receptor
C9E41_RS01580	COG3720	iron ion transport
C9E41_RS01585	COG2197	response regulator
C9E41_RS01590	COG3065	identical protein binding
C9E41_RS01600	COG1393	Belongs to the ArsC family
C9E41_RS01605	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C9E41_RS01610	COG0640	Transcriptional regulator
C9E41_RS01620	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C9E41_RS01625	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
C9E41_RS01630	COG0339	signal peptide processing
C9E41_RS01640	COG3104	oligopeptide transport
C9E41_RS01650	COG0589	response to stress
C9E41_RS01660	COG0306	phosphate transporter
C9E41_RS01665	COG2081	HI0933 family
C9E41_RS01685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C9E41_RS01690	COG1129	ABC transporter
C9E41_RS01690	COG0842	Transport permease protein
C9E41_RS01695	COG0842	Transport permease protein
C9E41_RS01710	COG0191	fructose-bisphosphate aldolase activity
C9E41_RS01725	COG3775	system Galactitol-specific IIC component
C9E41_RS01730	COG3414	Phosphotransferase system galactitol-specific IIB component
C9E41_RS01740	COG2188	Transcriptional regulator
C9E41_RS01750	COG1124	(ABC) transporter
C9E41_RS01755	COG0444	Belongs to the ABC transporter superfamily
C9E41_RS01760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C9E41_RS01765	COG0601	transmembrane transport
C9E41_RS01770	COG0747	negative chemotaxis
C9E41_RS01775	COG2091	lysine biosynthetic process via aminoadipic acid
C9E41_RS01780	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C9E41_RS01785	COG1028	Short-chain dehydrogenase reductase Sdr
C9E41_RS01795	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C9E41_RS01820	COG1216	Glycosyl transferase, family 2
C9E41_RS01840	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C9E41_RS01850	COG0204	Acyl-transferase
C9E41_RS01870	COG0628	permease
C9E41_RS01875	COG0477	Major facilitator Superfamily
C9E41_RS01885	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C9E41_RS01900	COG3714	YhhN family
C9E41_RS01910	COG3776	membrane
C9E41_RS01915	COG0742	ribosomal rna small subunit methyltransferase
C9E41_RS01920	COG0552	protein localization to endoplasmic reticulum
C9E41_RS01925	COG2884	Cell division ATP-binding protein ftsE
C9E41_RS01930	COG2177	Part of the ABC transporter FtsEX involved in
C9E41_RS01935	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C9E41_RS01940	COG0683	leucine binding
C9E41_RS01955	COG0456	acetyltransferase
C9E41_RS01960	COG0683	leucine binding
C9E41_RS01965	COG0559	Belongs to the binding-protein-dependent transport system permease family
C9E41_RS01970	COG4177	L-phenylalanine transmembrane transporter activity
C9E41_RS01975	COG0411	ABC transporter
C9E41_RS01980	COG0410	ABC transporter
C9E41_RS01990	COG1653	transport
C9E41_RS01995	COG1175	transmembrane transport
C9E41_RS02005	COG3842	ATPase activity
C9E41_RS02010	COG0584	glycerophosphoryl diester phosphodiesterase
C9E41_RS02020	COG0405	Gamma-glutamyltransferase
C9E41_RS02035	COG1247	-acetyltransferase
C9E41_RS02040	COG0673	inositol 2-dehydrogenase activity
C9E41_RS02045	COG1741	Belongs to the pirin family
C9E41_RS02050	COG1609	Transcriptional regulator
C9E41_RS02055	COG3265	gluconokinase activity
C9E41_RS02060	COG2610	gluconate transmembrane transporter activity
C9E41_RS02065	COG0514	ATP-dependent DNA helicase (RecQ)
C9E41_RS02085	COG2095	MarC family integral membrane protein
C9E41_RS02090	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C9E41_RS02095	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
C9E41_RS02115	COG0058	SHG alpha-glucan phosphorylase activity
C9E41_RS02120	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C9E41_RS02135	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C9E41_RS02150	COG1349	DNA-binding transcription factor activity
C9E41_RS02155	COG4650	regulator
C9E41_RS02160	COG1690	Belongs to the RtcB family
C9E41_RS02185	COG0058	SHG alpha-glucan phosphorylase activity
C9E41_RS02190	COG1640	4-alpha-glucanotransferase
C9E41_RS02195	COG2610	gluconate transmembrane transporter activity
C9E41_RS02205	COG1040	competence protein
C9E41_RS02215	COG5464	transposase or invertase
C9E41_RS02225	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
C9E41_RS02230	COG1918	ferrous iron import across plasma membrane
C9E41_RS02235	COG2183	response to ionizing radiation
C9E41_RS02240	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C9E41_RS02260	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
C9E41_RS02270	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C9E41_RS02275	COG1011	Hydrolase
C9E41_RS02285	COG0494	nUDIX hydrolase
C9E41_RS02290	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
C9E41_RS02295	COG4972	Pilus assembly protein
C9E41_RS02300	COG3166	PFAM Fimbrial assembly family protein
C9E41_RS02315	COG4796	Type ii and iii secretion system protein
C9E41_RS02330	COG3266	domain, Protein
C9E41_RS02335	COG0338	D12 class N6 adenine-specific DNA methyltransferase
C9E41_RS02340	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C9E41_RS02345	COG0546	phosphoglycolate phosphatase activity
C9E41_RS02350	COG0180	Tryptophanyl-tRNA synthetase
C9E41_RS02355	COG2188	Transcriptional regulator
C9E41_RS02365	COG1082	Xylose isomerase domain protein TIM barrel
C9E41_RS02370	COG2222	sugar isomerase
C9E41_RS02375	COG0531	amino acid
C9E41_RS02390	COG2116	formate transmembrane transporter activity
C9E41_RS02395	COG2146	nitrite reductase [NAD(P)H] activity
C9E41_RS02400	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C9E41_RS02415	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C9E41_RS02425	COG2184	nucleotidyltransferase activity
C9E41_RS02430	COG0512	Glutamine amidotransferase of anthranilate synthase
C9E41_RS02435	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C9E41_RS02440	COG1289	transmembrane transporter activity
C9E41_RS02445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C9E41_RS02450	COG1765	OsmC-like protein
C9E41_RS02455	COG3954	Phosphoribulokinase
C9E41_RS02465	COG0429	hydrolase of the alpha beta-hydrolase fold
C9E41_RS02470	COG0488	(ABC) transporter
C9E41_RS02485	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
C9E41_RS02490	COG1047	Peptidyl-prolyl cis-trans
C9E41_RS02500	COG0545	Peptidyl-prolyl cis-trans isomerase
C9E41_RS02505	COG2964	Protein conserved in bacteria
C9E41_RS02580	COG0089	rRNA binding
C9E41_RS02670	COG0201	protein transport
C9E41_RS02710	COG0789	Transcriptional regulator
C9E41_RS02715	COG3036	rescue of stalled ribosome
C9E41_RS02725	COG0569	domain protein
C9E41_RS02745	COG0758	DNA mediated transformation
C9E41_RS02755	COG0551	DNA topoisomerase type I activity
C9E41_RS02760	COG0009	L-threonylcarbamoyladenylate synthase
C9E41_RS02775	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C9E41_RS02820	COG1126	abc transporter atp-binding protein
C9E41_RS02825	COG0765	amino acid transport
C9E41_RS02830	COG4597	amino acid ABC transporter
C9E41_RS02835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9E41_RS02850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C9E41_RS02855	COG1309	transcriptional regulator
C9E41_RS02865	COG2189	Belongs to the N(4) N(6)-methyltransferase family
C9E41_RS02875	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C9E41_RS02885	COG4145	pantothenate transmembrane transporter activity
C9E41_RS02890	COG3924	membrane
C9E41_RS02895	COG0439	Biotin carboxylase
C9E41_RS02900	COG0511	ligase activity, forming carbon-carbon bonds
C9E41_RS02905	COG0604	alcohol dehydrogenase
C9E41_RS02910	COG2199	diguanylate cyclase activity
C9E41_RS02910	COG2200	EAL domain
C9E41_RS02915	COG1077	Cell shape determining protein MreB Mrl
C9E41_RS02920	COG1792	Involved in formation and maintenance of cell shape
C9E41_RS02925	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C9E41_RS02930	COG0424	maF-like protein
C9E41_RS02935	COG1530	ribonuclease E activity
C9E41_RS02940	COG3164	Protein of unknown function
C9E41_RS02945	COG0312	modulator of DNA gyrase
C9E41_RS02950	COG0583	DNA-binding transcription factor activity
C9E41_RS02970	COG2732	(Barnase) inhibitor
C9E41_RS02990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C9E41_RS02995	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C9E41_RS03000	COG3105	Protein conserved in bacteria
C9E41_RS03005	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
C9E41_RS03025	COG0625	glutathione transferase activity
C9E41_RS03030	COG2969	positive regulation of protein catabolic process
C9E41_RS03035	COG3069	C4-dicarboxylate transmembrane transporter activity
C9E41_RS03065	COG2731	YhcH YjgK YiaL family protein
C9E41_RS03070	COG4804	nuclease activity
C9E41_RS03075	COG0493	'glutamate synthase
C9E41_RS03080	COG0067	glutamate synthase
C9E41_RS03080	COG0070	glutamate synthase
C9E41_RS03080	COG0069	glutamate synthase activity
C9E41_RS03085	COG1242	4 iron, 4 sulfur cluster binding
C9E41_RS03090	COG0784	Response regulator, receiver
C9E41_RS03090	COG2198	Histidine kinase
C9E41_RS03090	COG5002	protein histidine kinase activity
C9E41_RS03095	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
C9E41_RS03105	COG0515	serine threonine protein kinase
C9E41_RS03110	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9E41_RS03125	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C9E41_RS03130	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C9E41_RS03135	COG1137	ATPase activity
C9E41_RS03140	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
C9E41_RS03145	COG3117	lipopolysaccharide transmembrane transporter activity
C9E41_RS03150	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
C9E41_RS03155	COG0517	IMP dehydrogenase activity
C9E41_RS03155	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C9E41_RS03160	COG0530	calcium, potassium:sodium antiporter activity
C9E41_RS03165	COG1127	ABC transporter
C9E41_RS03170	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C9E41_RS03175	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C9E41_RS03180	COG2854	intermembrane phospholipid transfer
C9E41_RS03185	COG3113	response to antibiotic
C9E41_RS03190	COG5007	Belongs to the BolA IbaG family
C9E41_RS03200	COG3423	Transcriptional regulator
C9E41_RS03205	COG0142	geranyltranstransferase activity
C9E41_RS03220	COG0697	spore germination
C9E41_RS03230	COG2027	D-alanyl-D-alanine carboxypeptidase
C9E41_RS03235	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C9E41_RS03240	COG1534	Rna-binding protein
C9E41_RS03250	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C9E41_RS03255	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C9E41_RS03265	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C9E41_RS03275	COG2194	sulfuric ester hydrolase activity
C9E41_RS03295	COG0195	Participates in both transcription termination and antitermination
C9E41_RS03335	COG0513	Belongs to the DEAD box helicase family
C9E41_RS03340	COG0814	amino acid
C9E41_RS03345	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C9E41_RS03350	COG0826	peptidase U32
C9E41_RS03355	COG0826	peptidase U32
C9E41_RS03360	COG3154	lipid carrier protein
C9E41_RS03365	COG3153	acetyltransferase
C9E41_RS03375	COG3787	Belongs to the UPF0306 family
C9E41_RS03380	COG0693	protein deglycase activity
C9E41_RS03385	COG0702	epimerase
C9E41_RS03390	COG0701	Predicted permease
C9E41_RS03395	COG2823	Periplasmic or secreted lipoprotein
C9E41_RS03415	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C9E41_RS03420	COG3539	Fimbrial protein
C9E41_RS03430	COG3539	Fimbrial protein
C9E41_RS03435	COG3188	usher protein
C9E41_RS03440	COG3121	Chaperone
C9E41_RS03445	COG3539	Fimbrial protein
C9E41_RS03455	COG3716	PTS system mannose fructose sorbose family IID component
C9E41_RS03465	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C9E41_RS03475	COG2222	sugar isomerase
C9E41_RS03480	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C9E41_RS03485	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9E41_RS03490	COG3716	PTS system mannose fructose sorbose family IID component
C9E41_RS03500	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C9E41_RS03510	COG1349	DNA-binding transcription factor activity
C9E41_RS03520	COG2002	toxin-antitoxin pair type II binding
C9E41_RS03525	COG2721	sulfolactate sulfo-lyase activity
C9E41_RS03530	COG2271	Major facilitator Superfamily
C9E41_RS03540	COG2084	Dehydrogenase
C9E41_RS03545	COG1929	Belongs to the glycerate kinase type-1 family
C9E41_RS03570	COG0583	DNA-binding transcription factor activity
C9E41_RS03575	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C9E41_RS03585	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C9E41_RS03590	COG1882	Formate acetyltransferase
C9E41_RS03595	COG0251	oxidation-reduction process
C9E41_RS03600	COG1760	l-serine dehydratase
C9E41_RS03605	COG0814	amino acid
C9E41_RS03620	COG1741	Belongs to the pirin family
C9E41_RS03625	COG0583	DNA-binding transcription factor activity
C9E41_RS03630	COG3152	Membrane
C9E41_RS03635	COG3152	Membrane
C9E41_RS03640	COG0435	Glutathione S-transferase
C9E41_RS03645	COG2259	Doxx family
C9E41_RS03655	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
C9E41_RS03660	COG4575	ribosome binding
C9E41_RS03665	COG1422	Protein of unknown function (DUF1090)
C9E41_RS03675	COG0586	Pfam SNARE associated Golgi protein
C9E41_RS03680	COG2186	Transcriptional regulator
C9E41_RS03685	COG2271	Major facilitator Superfamily
C9E41_RS03695	COG2721	sulfolactate sulfo-lyase activity
C9E41_RS03705	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
C9E41_RS03710	COG0861	Integral membrane protein TerC family
C9E41_RS03715	COG0673	inositol 2-dehydrogenase activity
C9E41_RS03720	COG2949	membrane
C9E41_RS03725	COG1451	nucleotide metabolic process
C9E41_RS03735	COG4680	protein conserved in bacteria
C9E41_RS03740	COG5499	transcription regulator containing HTH domain
C9E41_RS03745	COG0446	pyridine nucleotide-disulphide oxidoreductase
C9E41_RS03745	COG1902	pentaerythritol trinitrate reductase activity
C9E41_RS03750	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
C9E41_RS03750	COG3408	Glycogen debranching enzyme
C9E41_RS03760	COG0531	amino acid
C9E41_RS03765	COG2731	YhcH YjgK YiaL family protein
C9E41_RS03770	COG3250	beta-galactosidase activity
C9E41_RS03775	COG1609	Transcriptional regulator
C9E41_RS03780	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C9E41_RS03790	COG0840	transmembrane signaling receptor activity
C9E41_RS03795	COG1695	Transcriptional regulator
C9E41_RS03800	COG2375	cellular response to nickel ion
C9E41_RS03815	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C9E41_RS03820	COG0358	DNA primase activity
C9E41_RS03825	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C9E41_RS03830	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C9E41_RS03835	COG0471	metal ion transport
C9E41_RS03840	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C9E41_RS03845	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C9E41_RS03850	COG0583	DNA-binding transcription factor activity
C9E41_RS03860	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C9E41_RS03875	COG4991	sh3 domain protein
C9E41_RS03880	COG3025	triphosphatase activity
C9E41_RS03905	COG2268	Band 7 protein
C9E41_RS03910	COG1585	Membrane protein implicated in regulation of membrane protease activity
C9E41_RS03935	COG3384	dioxygenase
C9E41_RS03940	COG0754	glutathionylspermidine amidase activity
C9E41_RS03950	COG1538	Outer membrane efflux protein
C9E41_RS03955	COG0494	nUDIX hydrolase
C9E41_RS03960	COG3151	Protein conserved in bacteria
C9E41_RS03965	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C9E41_RS03970	COG3150	esterase
C9E41_RS03975	COG0187	DNA topoisomerase II activity
C9E41_RS03980	COG4774	siderophore transport
C9E41_RS03985	COG1120	ATPase activity
C9E41_RS03990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C9E41_RS03995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C9E41_RS04005	COG1737	Transcriptional regulator
C9E41_RS04010	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C9E41_RS04015	COG2249	NAD(P)H dehydrogenase (quinone) activity
C9E41_RS04020	COG0642	Histidine kinase
C9E41_RS04025	COG0745	RESPONSE REGULATOR receiver
C9E41_RS04030	COG3111	PFAM Bacterial OB fold (BOF) protein
C9E41_RS04035	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
C9E41_RS04040	COG4166	transmembrane transport
C9E41_RS04045	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C9E41_RS04050	COG0204	Acyl-transferase
C9E41_RS04055	COG2132	Multicopper oxidase
C9E41_RS04060	COG1032	radical SAM domain protein
C9E41_RS04065	COG4238	major outer membrane lipoprotein
C9E41_RS04075	COG0656	L-ascorbic acid biosynthetic process
C9E41_RS04080	COG1979	alcohol dehydrogenase
C9E41_RS04085	COG2207	Transcriptional regulator
C9E41_RS04090	COG0586	Pfam SNARE associated Golgi protein
C9E41_RS04095	COG0626	cystathionine gamma-synthase activity
C9E41_RS04100	COG0811	peptide transport
C9E41_RS04105	COG0848	biopolymer transport protein
C9E41_RS04110	COG1028	Short-chain dehydrogenase reductase Sdr
C9E41_RS04120	COG0667	Aldo Keto reductase
C9E41_RS04135	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
C9E41_RS04140	COG0437	4 iron, 4 sulfur cluster binding
C9E41_RS04145	COG5557	Pfam Polysulphide reductase, NrfD
C9E41_RS04150	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
C9E41_RS04155	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C9E41_RS04160	COG1773	rubredoxin
C9E41_RS04165	COG0375	protein maturation
C9E41_RS04170	COG0298	carbon dioxide binding
C9E41_RS04175	COG0625	glutathione transferase activity
C9E41_RS04180	COG0754	glutathionylspermidine amidase activity
C9E41_RS04205	COG3436	PFAM IS66 Orf2 family protein
C9E41_RS04215	COG4372	Transposase
C9E41_RS04220	COG3436	PFAM IS66 Orf2 family protein
C9E41_RS04310	COG3436	PFAM IS66 Orf2 family protein
C9E41_RS04330	COG0582	viral genome integration into host DNA
C9E41_RS04340	COG1811	Na channel or pump
C9E41_RS04345	COG1982	Orn Lys Arg decarboxylase major
C9E41_RS04350	COG2211	Major facilitator Superfamily
C9E41_RS04365	COG1194	a g-specific adenine glycosylase
C9E41_RS04375	COG3171	Protein conserved in bacteria
C9E41_RS04385	COG0252	asparaginase activity
C9E41_RS04395	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C9E41_RS04400	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C9E41_RS04410	COG0762	integral membrane protein
C9E41_RS04415	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C9E41_RS04420	COG2805	Type II/IV secretion system protein
C9E41_RS04435	COG0189	ligase activity
C9E41_RS04440	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C9E41_RS04445	COG2356	endonuclease I
C9E41_RS04450	COG3091	SprT-like family
C9E41_RS04455	COG2814	Major facilitator Superfamily
C9E41_RS04470	COG1166	arginine decarboxylase activity
C9E41_RS04485	COG0501	Belongs to the peptidase M48B family
C9E41_RS04490	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C9E41_RS04495	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9E41_RS04500	COG2213	PTS system mannitol-specific
C9E41_RS04505	COG1063	alcohol dehydrogenase
C9E41_RS04510	COG1494	fructose-1,6-bisphosphatase
C9E41_RS04520	COG1072	(Pantothenic acid kinase))
C9E41_RS04525	COG1122	ATPase activity
C9E41_RS04530	COG1122	ATPase activity
C9E41_RS04555	COG0126	phosphoglycerate kinase activity
C9E41_RS04560	COG0191	fructose-bisphosphate aldolase activity
C9E41_RS04565	COG0668	transmembrane transport
C9E41_RS04575	COG2968	Membrane
C9E41_RS04580	COG0583	DNA-binding transcription factor activity
C9E41_RS04585	COG0583	DNA-binding transcription factor activity
C9E41_RS04590	COG0427	acetyl-CoA hydrolase
C9E41_RS04595	COG1024	Enoyl-CoA hydratase
C9E41_RS04600	COG1703	isobutyryl-CoA mutase activity
C9E41_RS04605	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C9E41_RS04605	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C9E41_RS04620	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C9E41_RS04635	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C9E41_RS04655	COG0006	proline dipeptidase activity
C9E41_RS04660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C9E41_RS04665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C9E41_RS04690	COG2723	6-phospho-beta-galactosidase activity
C9E41_RS04700	COG1272	protein, Hemolysin III
C9E41_RS04710	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
C9E41_RS04720	COG0716	FMN binding
C9E41_RS04725	COG4974	Belongs to the 'phage' integrase family
C9E41_RS04730	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C9E41_RS04735	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C9E41_RS04745	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C9E41_RS04765	COG2233	PERMEase
C9E41_RS04770	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C9E41_RS04770	COG0493	'glutamate synthase
C9E41_RS04780	COG2252	PERMEase
C9E41_RS04785	COG0402	S-adenosylhomocysteine deaminase activity
C9E41_RS04790	COG2233	PERMEase
C9E41_RS04795	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C9E41_RS04795	COG2080	2 iron, 2 sulfur cluster binding
C9E41_RS04800	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C9E41_RS04805	COG0402	S-adenosylhomocysteine deaminase activity
C9E41_RS04810	COG0493	'glutamate synthase
C9E41_RS04810	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C9E41_RS04815	COG2068	MobA-Related Protein
C9E41_RS04820	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C9E41_RS04825	COG3608	succinylglutamate desuccinylase aspartoacylase
C9E41_RS04825	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C9E41_RS04830	COG0549	Belongs to the carbamate kinase family
C9E41_RS04840	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C9E41_RS04845	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C9E41_RS04850	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C9E41_RS04855	COG3829	transcription factor binding
C9E41_RS04860	COG2080	2 iron, 2 sulfur cluster binding
C9E41_RS04865	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C9E41_RS04870	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C9E41_RS04875	COG4942	peptidase
C9E41_RS04895	COG2207	Transcriptional regulator
C9E41_RS05005	COG2197	response regulator
C9E41_RS05010	COG0741	lytic transglycosylase activity
C9E41_RS05020	COG0457	Tetratricopeptide repeat
C9E41_RS05020	COG3710	Transcriptional regulator
C9E41_RS05030	COG0457	Tetratricopeptide repeat
C9E41_RS05055	COG3710	Transcriptional regulator
C9E41_RS05060	COG2771	luxR family
C9E41_RS05065	COG0814	amino acid
C9E41_RS05070	COG0183	Belongs to the thiolase family
C9E41_RS05080	COG1028	Short-chain dehydrogenase reductase Sdr
C9E41_RS05085	COG2814	Major facilitator Superfamily
C9E41_RS05090	COG1794	racemase activity, acting on amino acids and derivatives
C9E41_RS05095	COG0583	DNA-binding transcription factor activity
C9E41_RS05105	COG1609	Transcriptional regulator
C9E41_RS05125	COG0667	Aldo Keto reductase
C9E41_RS05135	COG0861	Integral membrane protein TerC family
C9E41_RS05155	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
C9E41_RS05170	COG2165	general secretion pathway protein
C9E41_RS05175	COG4795	General secretion pathway protein
C9E41_RS05185	COG4967	type IV pilus modification protein PilV
C9E41_RS05190	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
C9E41_RS05195	COG1025	Belongs to the peptidase M16 family
C9E41_RS05200	COG1074	ATP-dependent DNA helicase activity
C9E41_RS05205	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C9E41_RS05210	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C9E41_RS05210	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C9E41_RS05215	COG0860	N-Acetylmuramoyl-L-alanine amidase
C9E41_RS05235	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
C9E41_RS05240	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C9E41_RS05245	COG2166	iron-sulfur cluster assembly
C9E41_RS05250	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C9E41_RS05260	COG0583	DNA-binding transcription factor activity
C9E41_RS05265	COG2363	Small membrane protein
C9E41_RS05275	COG1349	DNA-binding transcription factor activity
C9E41_RS05285	COG1070	Carbohydrate kinase
C9E41_RS05295	COG0738	Major facilitator superfamily
C9E41_RS05300	COG0235	Class ii aldolase
C9E41_RS05305	COG1454	alcohol dehydrogenase
C9E41_RS05315	COG1760	l-serine dehydratase
C9E41_RS05320	COG0814	amino acid
C9E41_RS05325	COG1611	Belongs to the LOG family
C9E41_RS05340	COG3098	single-species biofilm formation
C9E41_RS05345	COG0564	pseudouridine synthase activity
C9E41_RS05350	COG0716	FMN binding
C9E41_RS05355	COG2271	Major facilitator Superfamily
C9E41_RS05360	COG4948	Mandelate Racemase Muconate Lactonizing
C9E41_RS05365	COG4948	Mandelate Racemase Muconate Lactonizing
C9E41_RS05370	COG4948	Mandelate Racemase Muconate Lactonizing
C9E41_RS05375	COG3850	Histidine kinase
C9E41_RS05375	COG3437	response regulator, receiver
C9E41_RS05375	COG4999	Histidine kinase
C9E41_RS05375	COG2205	protein histidine kinase activity
C9E41_RS05380	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C9E41_RS05385	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C9E41_RS05390	COG2336	PFAM SpoVT AbrB
C9E41_RS05395	COG2337	Toxic component of a toxin-antitoxin (TA) module
C9E41_RS05400	COG3956	TIGRFAM MazG family protein
C9E41_RS05415	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
C9E41_RS05420	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
C9E41_RS05430	COG0602	queuosine metabolic process
C9E41_RS05435	COG1070	Carbohydrate kinase
C9E41_RS05440	COG2223	nitrite transmembrane transporter activity
C9E41_RS05445	COG1028	Short-chain dehydrogenase reductase Sdr
C9E41_RS05450	COG0277	FAD linked oxidase domain protein
C9E41_RS05460	COG2086	electron transfer activity
C9E41_RS05470	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
C9E41_RS05475	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C9E41_RS05480	COG0644	oxidoreductase
C9E41_RS05485	COG0720	synthase
C9E41_RS05490	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C9E41_RS05515	COG1203	CRISPR-associated helicase, Cas3
C9E41_RS05530	COG1857	crispr-associated protein
C9E41_RS05545	COG1518	maintenance of DNA repeat elements
C9E41_RS05550	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C9E41_RS05555	COG2234	aminopeptidase activity
C9E41_RS05610	COG4942	peptidase
C9E41_RS05610	COG1388	LysM domain
C9E41_RS05615	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C9E41_RS05620	COG1846	Transcriptional regulator
C9E41_RS05625	COG0163	prenyltransferase activity
C9E41_RS05630	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C9E41_RS05640	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C9E41_RS05655	COG3604	Transcriptional regulator
C9E41_RS05660	COG0309	Hydrogenase expression formation protein (HypE)
C9E41_RS05665	COG0409	Hydrogenase expression formation protein
C9E41_RS05670	COG0298	carbon dioxide binding
C9E41_RS05675	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
C9E41_RS05680	COG0375	protein maturation
C9E41_RS05690	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C9E41_RS05695	COG0651	ATP synthesis coupled electron transport
C9E41_RS05700	COG0650	Formate hydrogenlyase subunit 4
C9E41_RS05705	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
C9E41_RS05705	COG3261	NADH dehydrogenase
C9E41_RS05710	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C9E41_RS05715	COG3260	NADH ubiquinone oxidoreductase 20
C9E41_RS05725	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C9E41_RS05730	COG2723	6-phospho-beta-galactosidase activity
C9E41_RS05735	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C9E41_RS05735	COG1263	PTS System
C9E41_RS05740	COG1609	Transcriptional regulator
C9E41_RS05745	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C9E41_RS05750	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
C9E41_RS05760	COG0426	domain, Protein
C9E41_RS05760	COG1773	rubredoxin
C9E41_RS05770	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C9E41_RS05770	COG0517	IMP dehydrogenase activity
C9E41_RS05775	COG1349	DNA-binding transcription factor activity
C9E41_RS05780	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9E41_RS05785	COG1028	Short-chain dehydrogenase reductase Sdr
C9E41_RS05805	COG2951	lytic endotransglycosylase activity
C9E41_RS05810	COG1546	Belongs to the CinA family
C9E41_RS05825	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C9E41_RS05830	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
C9E41_RS05860	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C9E41_RS05865	COG1238	metal cluster binding
C9E41_RS05880	COG2814	Major facilitator Superfamily
C9E41_RS05885	COG1566	PFAM secretion protein HlyD family protein
C9E41_RS05890	COG1846	Transcriptional regulator
C9E41_RS05900	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
C9E41_RS05905	COG2814	Major facilitator Superfamily
C9E41_RS05910	COG2113	Glycine betaine
C9E41_RS05915	COG4176	ABC-type proline glycine betaine transport system permease component
C9E41_RS05920	COG4175	Glycine betaine
C9E41_RS05925	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C9E41_RS05930	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C9E41_RS05940	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C9E41_RS05950	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C9E41_RS05960	COG4575	ribosome binding
C9E41_RS05975	COG2916	Histone family protein nucleoid-structuring protein H-NS
C9E41_RS05980	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C9E41_RS05985	COG0640	Transcriptional regulator
C9E41_RS05990	COG0401	homolog of Blt101
C9E41_RS05995	COG1652	LysM domain
C9E41_RS06000	COG1802	Transcriptional regulator
C9E41_RS06005	COG1113	amino acid transport
C9E41_RS06010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C9E41_RS06015	COG1012	belongs to the aldehyde dehydrogenase family
C9E41_RS06020	COG0579	oxidoreductase
C9E41_RS06055	COG3468	outer membrane autotransporter barrel domain protein
C9E41_RS06105	COG2826	transposase and inactivated derivatives, IS30 family
C9E41_RS06165	COG3436	PFAM IS66 Orf2 family protein
C9E41_RS06215	COG0727	PFAM Uncharacterised protein family (UPF0153)
C9E41_RS06240	COG2867	negative regulation of translational initiation
C9E41_RS06250	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C9E41_RS06255	COG0497	DNA recombination
C9E41_RS06270	COG4536	flavin adenine dinucleotide binding
C9E41_RS06275	COG4137	Cytochrome C assembly protein
C9E41_RS06280	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C9E41_RS06305	COG2885	chlorophyll binding
C9E41_RS06310	COG2199	diguanylate cyclase activity
C9E41_RS06325	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C9E41_RS06330	COG0287	Prephenate dehydrogenase
C9E41_RS06330	COG1605	Chorismate mutase
C9E41_RS06335	COG0077	Prephenate dehydratase
C9E41_RS06335	COG1605	Chorismate mutase
C9E41_RS06345	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C9E41_RS06350	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C9E41_RS06355	COG0564	pseudouridine synthase activity
C9E41_RS06365	COG0542	response to heat
C9E41_RS06390	COG0477	Major facilitator Superfamily
C9E41_RS06395	COG5544	Lipoprotein
C9E41_RS06400	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C9E41_RS06405	COG0045	succinate-CoA ligase (ADP-forming) activity
C9E41_RS06405	COG1042	CoA-binding domain protein
C9E41_RS06405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C9E41_RS06410	COG3148	PFAM DTW domain containing protein
C9E41_RS06415	COG3118	belongs to the thioredoxin family
C9E41_RS06420	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C9E41_RS06435	COG1280	lysine exporter protein (LysE YggA)
C9E41_RS06440	COG0583	DNA-binding transcription factor activity
C9E41_RS06445	COG0513	Belongs to the DEAD box helicase family
C9E41_RS06450	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C9E41_RS06455	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C9E41_RS06465	COG1595	DNA-templated transcription, initiation
C9E41_RS06470	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
C9E41_RS06475	COG3026	antisigma factor binding
C9E41_RS06480	COG3086	response to oxidative stress
C9E41_RS06490	COG0681	Belongs to the peptidase S26 family
C9E41_RS06510	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
C9E41_RS06525	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C9E41_RS06530	COG1737	Transcriptional regulator
C9E41_RS06535	COG0560	Phosphoserine phosphatase
C9E41_RS06540	COG0590	tRNA wobble adenosine to inosine editing
C9E41_RS06545	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
C9E41_RS06550	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C9E41_RS06550	COG0047	phosphoribosylformylglycinamidine synthase activity
C9E41_RS06555	COG2205	protein histidine kinase activity
C9E41_RS06560	COG3170	Tfp pilus assembly protein FimV
C9E41_RS06565	COG2204	response regulator
C9E41_RS06570	COG0347	Belongs to the P(II) protein family
C9E41_RS06575	COG1017	nitric oxide dioxygenase activity
C9E41_RS06575	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C9E41_RS06585	COG1940	carbohydrate kinase activity
C9E41_RS06590	COG0457	Tetratricopeptide repeat
C9E41_RS06595	COG1879	ABC-type sugar transport system periplasmic component
C9E41_RS06600	COG1129	ABC transporter
C9E41_RS06605	COG1172	Belongs to the binding-protein-dependent transport system permease family
C9E41_RS06615	COG2017	converts alpha-aldose to the beta-anomer
C9E41_RS06620	COG2259	Doxx family
C9E41_RS06645	COG4638	Rieske (2fe-2S)
C9E41_RS06650	COG0583	DNA-binding transcription factor activity
C9E41_RS06655	COG2814	Major facilitator Superfamily
C9E41_RS06660	COG3711	transcriptional antiterminator
C9E41_RS06665	COG1073	alpha beta
C9E41_RS06670	COG0483	inositol monophosphate 1-phosphatase activity
C9E41_RS06690	COG0822	iron-sulfur transferase activity
C9E41_RS06710	COG0633	Ferredoxin
C9E41_RS06715	COG2975	iron-sulfur cluster assembly
C9E41_RS06730	COG2897	thiosulfate sulfurtransferase activity
C9E41_RS06735	COG2373	Large extracellular alpha-helical protein
C9E41_RS06740	COG4953	penicillin-binding protein 1C
C9E41_RS06745	COG0243	molybdopterin cofactor binding
C9E41_RS06750	COG0437	4 iron, 4 sulfur cluster binding
C9E41_RS06755	COG3302	dmso reductase anchor subunit
C9E41_RS06790	COG2976	Protein conserved in bacteria
C9E41_RS06805	COG1645	bacterial-type flagellum-dependent swarming motility
C9E41_RS06815	COG0516	GMP reductase activity
C9E41_RS06815	COG0517	IMP dehydrogenase activity
C9E41_RS06830	COG3133	Outer membrane lipoprotein
C9E41_RS06840	COG2200	EAL domain
C9E41_RS06845	COG0248	Ppx GppA phosphatase
C9E41_RS06850	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
C9E41_RS06855	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C9E41_RS06870	COG2233	PERMEase
C9E41_RS06880	COG1393	Belongs to the ArsC family
C9E41_RS06885	COG4783	chaperone-mediated protein folding
C9E41_RS06890	COG0628	permease
C9E41_RS06895	COG2116	formate transmembrane transporter activity
C9E41_RS06900	COG3604	Transcriptional regulator
C9E41_RS06910	COG3260	NADH ubiquinone oxidoreductase 20
C9E41_RS06915	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C9E41_RS06920	COG3261	NADH dehydrogenase
C9E41_RS06920	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
C9E41_RS06925	COG0651	ATP synthesis coupled electron transport
C9E41_RS06930	COG4237	Hydrogenase 4 membrane
C9E41_RS06935	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C9E41_RS06940	COG0650	Formate hydrogenlyase subunit 4
C9E41_RS06945	COG0651	ATP synthesis coupled electron transport
C9E41_RS06950	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C9E41_RS06955	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C9E41_RS06960	COG2716	regulation of RNA biosynthetic process
C9E41_RS06970	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
C9E41_RS06980	COG2321	neutral zinc metallopeptidase
C9E41_RS06990	COG0400	carboxylic ester hydrolase activity
C9E41_RS07005	COG1393	Belongs to the ArsC family
C9E41_RS07020	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C9E41_RS07025	COG3850	Histidine kinase
C9E41_RS07030	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C9E41_RS07030	COG0493	'glutamate synthase
C9E41_RS07040	COG5342	invasion associated locus B
C9E41_RS07045	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C9E41_RS07050	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C9E41_RS07055	COG0280	phosphate acetyltransferase
C9E41_RS07055	COG0281	malic enzyme
C9E41_RS07060	COG4810	utilization protein
C9E41_RS07065	COG4917	ethanolamine utilization protein
C9E41_RS07070	COG4766	ethanolamine catabolic process
C9E41_RS07075	COG4812	Cobalamin adenosyltransferase
C9E41_RS07080	COG0280	phosphate acetyltransferase
C9E41_RS07085	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
C9E41_RS07090	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
C9E41_RS07095	COG1012	belongs to the aldehyde dehydrogenase family
C9E41_RS07100	COG4820	ethanolamine utilization protein (EutJ)
C9E41_RS07105	COG1454	alcohol dehydrogenase
C9E41_RS07110	COG3192	ethanolamine utilization protein
C9E41_RS07115	COG4819	ethanolamine utilization protein
C9E41_RS07120	COG4303	Ethanolamine ammonia lyase large subunit
C9E41_RS07130	COG4816	utilization protein
C9E41_RS07135	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
C9E41_RS07140	COG2207	Transcriptional regulator
C9E41_RS07150	COG0860	N-Acetylmuramoyl-L-alanine amidase
C9E41_RS07170	COG2837	iron assimilation
C9E41_RS07175	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C9E41_RS07180	COG1263	PTS System
C9E41_RS07180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C9E41_RS07195	COG1028	Short-chain dehydrogenase reductase Sdr
C9E41_RS07200	COG4150	thiosulfate binding
C9E41_RS07205	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
C9E41_RS07210	COG4208	sulfate ABC transporter
C9E41_RS07215	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C9E41_RS07220	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C9E41_RS07235	COG2190	(PTS) system
C9E41_RS07240	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C9E41_RS07245	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9E41_RS07250	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C9E41_RS07270	COG3530	Putative quorum-sensing-regulated virulence factor
C9E41_RS07275	COG0385	Bile acid
C9E41_RS07320	COG0675	Transposase, IS605 OrfB family
C9E41_RS07325	COG3415	Transposase
C9E41_RS07330	COG3415	Transposase
C9E41_RS07345	COG2200	EAL domain
C9E41_RS07345	COG2199	diguanylate cyclase activity
C9E41_RS07350	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C9E41_RS07375	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C9E41_RS07380	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C9E41_RS07385	COG0006	proline dipeptidase activity
C9E41_RS07390	COG1363	Peptidase, m42
C9E41_RS07395	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9E41_RS07395	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9E41_RS07395	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C9E41_RS07400	COG2207	Transcriptional regulator
C9E41_RS07405	COG3279	Response regulator of the LytR AlgR family
C9E41_RS07410	COG3275	phosphorelay sensor kinase activity
C9E41_RS07415	COG0436	Aminotransferase
C9E41_RS07425	COG1560	Kdo2-lipid A biosynthetic process
C9E41_RS07450	COG0028	Belongs to the TPP enzyme family
C9E41_RS07455	COG0679	Auxin Efflux Carrier
C9E41_RS07465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9E41_RS07465	COG2198	Histidine kinase
C9E41_RS07465	COG2205	protein histidine kinase activity
C9E41_RS07465	COG0784	Response regulator, receiver
C9E41_RS07470	COG2197	response regulator
C9E41_RS07475	COG1566	PFAM secretion protein HlyD family protein
C9E41_RS07480	COG0477	Major facilitator Superfamily
C9E41_RS07555	COG0582	viral genome integration into host DNA
C9E41_RS07565	COG2116	formate transmembrane transporter activity
C9E41_RS07570	COG2853	Lipoprotein
C9E41_RS07585	COG2067	long-chain fatty acid transport protein
C9E41_RS07590	COG3691	Protein conserved in bacteria
C9E41_RS07600	COG1024	Enoyl-CoA hydratase
C9E41_RS07600	COG1250	3-hydroxyacyl-CoA dehydrogenase
C9E41_RS07605	COG2062	phosphohistidine phosphatase, SixA
C9E41_RS07610	COG3539	Fimbrial protein
C9E41_RS07615	COG3188	usher protein
C9E41_RS07620	COG3121	Chaperone
C9E41_RS07625	COG3539	Fimbrial protein
C9E41_RS07630	COG3539	Fimbrial protein
C9E41_RS07635	COG3539	Fimbrial protein
C9E41_RS07665	COG0730	response to heat
C9E41_RS07670	COG3101	peptidyl-lysine hydroxylation
C9E41_RS07680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C9E41_RS07680	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
C9E41_RS07685	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C9E41_RS07690	COG2814	Major facilitator Superfamily
C9E41_RS07705	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C9E41_RS07715	COG0586	Pfam SNARE associated Golgi protein
C9E41_RS07725	COG0285	dihydrofolate synthase activity
C9E41_RS07730	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
C9E41_RS07735	COG1286	toxin biosynthetic process
C9E41_RS07740	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C9E41_RS07745	COG0163	prenyltransferase activity
C9E41_RS07750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9E41_RS07755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9E41_RS07760	COG4215	(ABC) transporter
C9E41_RS07765	COG4160	amino acid transport
C9E41_RS07770	COG4598	ABC transporter
C9E41_RS07775	COG5464	transposase or invertase
C9E41_RS07780	COG1090	epimerase
C9E41_RS07785	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C9E41_RS07790	COG0625	glutathione transferase activity
C9E41_RS07795	COG0625	glutathione transferase activity
C9E41_RS07800	COG0622	Phosphoesterase
C9E41_RS07805	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
C9E41_RS07810	COG1288	antiporter activity
C9E41_RS07815	COG0280	phosphate acetyltransferase
C9E41_RS07815	COG0857	belongs to the CobB CobQ family
C9E41_RS07820	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C9E41_RS07835	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C9E41_RS07840	COG0490	domain, Protein
C9E41_RS07840	COG0471	metal ion transport
C9E41_RS07850	COG0436	Aminotransferase
C9E41_RS07855	COG0583	DNA-binding transcription factor activity
C9E41_RS07875	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
C9E41_RS07880	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
C9E41_RS07885	COG1034	ATP synthesis coupled electron transport
C9E41_RS07900	COG0839	Belongs to the complex I subunit 6 family
C9E41_RS07910	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C9E41_RS07915	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C9E41_RS07935	COG5160	protein modification by small protein removal
C9E41_RS07940	COG1234	tRNA 3'-trailer cleavage
C9E41_RS07945	COG2153	protein acetylation
C9E41_RS07950	COG4575	ribosome binding
C9E41_RS07955	COG1169	isochorismate synthase
C9E41_RS07970	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C9E41_RS07980	COG0318	PFAM AMP-dependent synthetase and ligase
C9E41_RS08025	COG0406	alpha-ribazole phosphatase activity
C9E41_RS08045	COG1414	Transcriptional regulator
C9E41_RS08050	COG4948	Mandelate Racemase Muconate Lactonizing
C9E41_RS08055	COG2271	Major facilitator Superfamily
C9E41_RS08070	COG3836	Belongs to the HpcH HpaI aldolase family
C9E41_RS08075	COG5464	transposase or invertase
C9E41_RS08080	COG0247	lactate metabolic process
C9E41_RS08090	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C9E41_RS08095	COG2271	Major facilitator Superfamily
C9E41_RS08100	COG0584	glycerophosphoryl diester phosphodiesterase
C9E41_RS08110	COG0583	DNA-binding transcription factor activity
C9E41_RS08115	COG2814	Major facilitator Superfamily
C9E41_RS08120	COG3642	lipopolysaccharide core region biosynthetic process
C9E41_RS08125	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C9E41_RS08130	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C9E41_RS08135	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C9E41_RS08140	COG3468	outer membrane autotransporter barrel domain protein
C9E41_RS08150	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C9E41_RS08155	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
C9E41_RS08160	COG3234	Protein of unknown function (DUF1175)
C9E41_RS08165	COG2373	Large extracellular alpha-helical protein
C9E41_RS08175	COG4676	Protein conserved in bacteria
C9E41_RS08180	COG0784	Response regulator, receiver
C9E41_RS08180	COG2205	protein histidine kinase activity
C9E41_RS08185	COG2197	response regulator
C9E41_RS08190	COG0642	Histidine kinase
C9E41_RS08190	COG2198	Histidine kinase
C9E41_RS08195	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C9E41_RS08200	COG1477	protein flavinylation
C9E41_RS08205	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C9E41_RS08205	COG2169	Transcriptional regulator
C9E41_RS08210	COG3145	DNA-N1-methyladenine dioxygenase activity
C9E41_RS08215	COG4615	Cyclic peptide transporter
C9E41_RS08230	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C9E41_RS08230	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
C9E41_RS08235	COG3062	negative regulation of establishment of protein localization
C9E41_RS08245	COG0437	4 iron, 4 sulfur cluster binding
C9E41_RS08250	COG0348	domain, Protein
C9E41_RS08255	COG3043	anaerobic respiration
C9E41_RS08260	COG3005	denitrification pathway
C9E41_RS08265	COG4133	protoheme IX ABC transporter activity
C9E41_RS08270	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C9E41_RS08275	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C9E41_RS08280	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C9E41_RS08290	COG1138	Cytochrome C-type biogenesis protein
C9E41_RS08295	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C9E41_RS08300	COG3088	subunit of a heme lyase
C9E41_RS08300	COG4235	cytochrome complex assembly
C9E41_RS08305	COG2197	response regulator
C9E41_RS08310	COG3468	outer membrane autotransporter barrel domain protein
C9E41_RS08320	COG3083	sulfuric ester hydrolase activity
C9E41_RS08340	COG1061	Type III restriction enzyme res subunit
C9E41_RS08345	COG1187	pseudouridine synthase activity
C9E41_RS08350	COG2814	Major facilitator Superfamily
C9E41_RS08360	COG4172	Belongs to the ABC transporter superfamily
C9E41_RS08365	COG4239	(ABC) transporter, permease
C9E41_RS08370	COG4174	ABC transporter (Permease)
C9E41_RS08375	COG4166	transmembrane transport
C9E41_RS08380	COG2200	EAL domain
C9E41_RS08385	COG0791	NLP P60 protein
C9E41_RS08390	COG0671	phosphoesterase, PA-phosphatase related
C9E41_RS08395	COG0523	cobalamin synthesis protein
C9E41_RS08400	COG0246	Mannitol dehydrogenase
C9E41_RS08415	COG2814	Major facilitator Superfamily
C9E41_RS08420	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9E41_RS08420	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9E41_RS08425	COG1105	Belongs to the carbohydrate kinase PfkB family
C9E41_RS08430	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C9E41_RS08430	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
C9E41_RS08430	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C9E41_RS08435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C9E41_RS08440	COG2313	pseudouridylate synthase activity
C9E41_RS08445	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C9E41_RS08450	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C9E41_RS08460	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C9E41_RS08465	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C9E41_RS08465	COG1522	sequence-specific DNA binding
C9E41_RS08475	COG2855	membrane
C9E41_RS08480	COG0583	DNA-binding transcription factor activity
C9E41_RS08485	COG0833	amino acid
C9E41_RS08490	COG4771	TonB-dependent receptor
C9E41_RS08495	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
C9E41_RS08505	COG2311	Membrane
C9E41_RS08510	COG1609	Transcriptional regulator
C9E41_RS08515	COG1879	ABC-type sugar transport system periplasmic component
C9E41_RS08520	COG1129	ABC transporter
C9E41_RS08525	COG4211	Belongs to the binding-protein-dependent transport system permease family
C9E41_RS08530	COG0167	dihydroorotate dehydrogenase activity
C9E41_RS08530	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
C9E41_RS08535	COG0493	'glutamate synthase
C9E41_RS08545	COG2949	membrane
C9E41_RS08555	COG1346	cytolysis
C9E41_RS08570	COG2271	Major facilitator Superfamily
C9E41_RS08585	COG0625	glutathione transferase activity
C9E41_RS08590	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C9E41_RS08595	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C9E41_RS08605	COG1538	Outer membrane efflux protein
C9E41_RS08610	COG1028	Short-chain dehydrogenase reductase Sdr
C9E41_RS08615	COG0586	Pfam SNARE associated Golgi protein
C9E41_RS08625	COG1686	Belongs to the peptidase S11 family
C9E41_RS08630	COG0277	FAD linked oxidase domain protein
C9E41_RS08635	COG1472	Belongs to the glycosyl hydrolase 3 family
C9E41_RS08640	COG1732	Glycine betaine
C9E41_RS08645	COG1174	glycine betaine transport
C9E41_RS08650	COG1125	glycine betaine transport
C9E41_RS08655	COG1174	glycine betaine transport
C9E41_RS08665	COG0789	Transcriptional regulator
C9E41_RS08670	COG0582	viral genome integration into host DNA
C9E41_RS08915	COG3772	lysozyme
C9E41_RS08965	COG0740	serine-type endopeptidase activity
C9E41_RS09050	COG5301	cellulose 1,4-beta-cellobiosidase activity
C9E41_RS09075	COG3275	phosphorelay sensor kinase activity
C9E41_RS09080	COG3279	Response regulator of the LytR AlgR family
C9E41_RS09085	COG4807	Protein conserved in bacteria
C9E41_RS09090	COG4808	Protein conserved in bacteria
C9E41_RS09095	COG4715	Zinc finger, swim domain protein
C9E41_RS09100	COG3552	Protein containing von Willebrand factor type A (VWA) domain
C9E41_RS09105	COG2425	protein containing a von Willebrand factor type A (vWA) domain
C9E41_RS09110	COG2425	protein containing a von Willebrand factor type A (vWA) domain
C9E41_RS09115	COG0714	Associated with various cellular activities
C9E41_RS09125	COG3831	ATPase activity
C9E41_RS09130	COG3831	ATPase activity
C9E41_RS09135	COG3831	ATPase activity
C9E41_RS09150	COG0489	protein tyrosine kinase activity
C9E41_RS09160	COG3539	Fimbrial protein
C9E41_RS09165	COG3121	Chaperone
C9E41_RS09170	COG3188	usher protein
C9E41_RS09175	COG3539	Fimbrial protein
C9E41_RS09180	COG5455	response to cobalt ion
C9E41_RS09185	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
C9E41_RS09220	COG0351	phosphomethylpyrimidine kinase
C9E41_RS09225	COG3757	hydrolase, family 25
C9E41_RS09230	COG2188	Transcriptional regulator
C9E41_RS09235	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C9E41_RS09240	COG1397	ADP-ribosylglycohydrolase
C9E41_RS09245	COG2211	Major facilitator Superfamily
C9E41_RS09250	COG1830	Aldolase
C9E41_RS09265	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9E41_RS09270	COG3414	Phosphotransferase system galactitol-specific IIB component
C9E41_RS09275	COG3775	system Galactitol-specific IIC component
C9E41_RS09280	COG1063	alcohol dehydrogenase
C9E41_RS09305	COG0826	peptidase U32
C9E41_RS09310	COG3422	double-strand break repair
C9E41_RS09315	COG0745	RESPONSE REGULATOR receiver
C9E41_RS09320	COG2205	protein histidine kinase activity
C9E41_RS09335	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C9E41_RS09360	COG4245	von Willebrand factor, type A
C9E41_RS09365	COG0631	protein serine/threonine phosphatase activity
C9E41_RS09370	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
C9E41_RS09375	COG0443	Heat shock 70 kDa protein
C9E41_RS09380	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C9E41_RS09390	COG0572	uridine kinase
C9E41_RS09400	COG2982	Protein involved in outer membrane biogenesis
C9E41_RS09415	COG1253	flavin adenine dinucleotide binding
C9E41_RS09420	COG1596	polysaccharide export
C9E41_RS09425	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C9E41_RS09430	COG0489	protein tyrosine kinase activity
C9E41_RS09430	COG3206	protein involved in exopolysaccharide biosynthesis
C9E41_RS09435	COG0463	Glycosyl transferase, family 2
C9E41_RS09440	COG1045	serine acetyltransferase
C9E41_RS09445	COG0438	transferase activity, transferring glycosyl groups
C9E41_RS09455	COG1216	Glycosyl transferase, family 2
C9E41_RS09460	COG0110	maltose O-acetyltransferase activity
C9E41_RS09465	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
C9E41_RS09470	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C9E41_RS09475	COG1051	belongs to the nudix hydrolase family
C9E41_RS09480	COG0297	glycogen (starch) synthase activity
C9E41_RS09485	COG0662	Cupin 2, conserved barrel domain protein
C9E41_RS09485	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
C9E41_RS09490	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C9E41_RS09495	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C9E41_RS09500	COG2244	polysaccharide biosynthetic process
C9E41_RS09505	COG2327	Polysaccharide pyruvyl transferase
C9E41_RS09510	COG0438	transferase activity, transferring glycosyl groups
C9E41_RS09520	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C9E41_RS09525	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C9E41_RS09550	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C9E41_RS09560	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
C9E41_RS09565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C9E41_RS09570	COG1051	belongs to the nudix hydrolase family
C9E41_RS09575	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
C9E41_RS09575	COG0662	Cupin 2, conserved barrel domain protein
C9E41_RS09580	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C9E41_RS09595	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C9E41_RS09600	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C9E41_RS09630	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C9E41_RS09635	COG0131	Imidazoleglycerol-phosphate dehydratase
C9E41_RS09635	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C9E41_RS09645	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C9E41_RS09660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C9E41_RS09665	COG0583	DNA-binding transcription factor activity
C9E41_RS09675	COG0531	amino acid
C9E41_RS09680	COG2391	methyltransferase activity
C9E41_RS09685	COG0425	Belongs to the sulfur carrier protein TusA family
C9E41_RS09690	COG2925	Exonuclease
C9E41_RS09695	COG1686	Belongs to the peptidase S11 family
C9E41_RS09705	COG1289	transmembrane transporter activity
C9E41_RS09715	COG4917	ethanolamine utilization protein
C9E41_RS09750	COG2003	Belongs to the UPF0758 family
C9E41_RS09800	COG4771	TonB-dependent receptor
C9E41_RS09815	COG4372	Transposase
C9E41_RS09820	COG3436	PFAM IS66 Orf2 family protein
C9E41_RS09835	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
C9E41_RS09850	COG1376	ErfK ybiS ycfS ynhG family protein
C9E41_RS09860	COG0583	DNA-binding transcription factor activity
C9E41_RS09865	COG0583	DNA-binding transcription factor activity
C9E41_RS09885	COG0217	transcriptional regulatory protein
C9E41_RS09890	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C9E41_RS09895	COG0477	Major facilitator Superfamily
C9E41_RS09905	COG1388	LysM domain
C9E41_RS09905	COG2373	Large extracellular alpha-helical protein
C9E41_RS09905	COG4932	domain protein
C9E41_RS09935	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C9E41_RS09980	COG1846	Transcriptional regulator
C9E41_RS10030	COG1403	HNH endonuclease
C9E41_RS10035	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C9E41_RS10095	COG3772	lysozyme
C9E41_RS10130	COG4220	transposase activity
C9E41_RS10215	COG5301	cellulose 1,4-beta-cellobiosidase activity
C9E41_RS10240	COG3038	cytochrome b561
C9E41_RS10245	COG3443	Belongs to the bacterial solute-binding protein 9 family
C9E41_RS10260	COG2351	hydroxyisourate hydrolase activity
C9E41_RS10265	COG0745	RESPONSE REGULATOR receiver
C9E41_RS10270	COG2205	protein histidine kinase activity
C9E41_RS10295	COG1418	mRNA catabolic process
C9E41_RS10300	COG0270	DNA (cytosine-5-)-methyltransferase activity
C9E41_RS10305	COG3727	T/G mismatch-specific endonuclease activity
C9E41_RS10310	COG0697	spore germination
C9E41_RS10315	COG2354	Protein conserved in bacteria
C9E41_RS10320	COG5475	Uncharacterized small protein (DUF2158)
C9E41_RS10325	COG3706	GGDEF domain
C9E41_RS10350	COG2197	response regulator
C9E41_RS10355	COG1684	flagellar biosynthetic protein fliR
C9E41_RS10360	COG1987	bacterial-type flagellum assembly
C9E41_RS10365	COG1338	Plays a role in the flagellum-specific transport system
C9E41_RS10370	COG3190	flagellar
C9E41_RS10375	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C9E41_RS10380	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C9E41_RS10385	COG1580	Controls the rotational direction of flagella during chemotaxis
C9E41_RS10390	COG3144	bacterial-type flagellum assembly
C9E41_RS10395	COG2882	bacterial-type flagellum organization
C9E41_RS10400	COG1157	protein secretion by the type III secretion system
C9E41_RS10405	COG1317	bacterial-type flagellum organization
C9E41_RS10410	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C9E41_RS10415	COG1766	The M ring may be actively involved in energy transduction
C9E41_RS10435	COG0454	-acetyltransferase
C9E41_RS10450	COG0454	-acetyltransferase
C9E41_RS10455	COG2135	peptidase activity
C9E41_RS10460	COG0425	Belongs to the sulfur carrier protein TusA family
C9E41_RS10465	COG2391	methyltransferase activity
C9E41_RS10475	COG0366	Alpha amylase catalytic
C9E41_RS10485	COG1516	flagellar protein fliS
C9E41_RS10490	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C9E41_RS10500	COG1191	sigma factor activity
C9E41_RS10510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9E41_RS10520	COG0765	amino acid transport
C9E41_RS10525	COG1126	abc transporter atp-binding protein
C9E41_RS10530	COG2197	response regulator
C9E41_RS10550	COG2197	response regulator
C9E41_RS10590	COG2826	transposase and inactivated derivatives, IS30 family
C9E41_RS10740	COG4974	Belongs to the 'phage' integrase family
C9E41_RS10745	COG3318	Belongs to the UPF0149 family
C9E41_RS10745	COG3012	SEC-C Motif Domain Protein
C9E41_RS10750	COG0814	amino acid
C9E41_RS10760	COG1528	Iron-storage protein
C9E41_RS10780	COG1528	Iron-storage protein
C9E41_RS10785	COG1879	ABC-type sugar transport system periplasmic component
C9E41_RS10790	COG1129	ABC transporter
C9E41_RS10800	COG1877	trehalose-phosphatase activity
C9E41_RS10805	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
C9E41_RS10810	COG0589	response to stress
C9E41_RS10825	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C9E41_RS10830	COG1360	Flagellar Motor Protein
C9E41_RS10835	COG2198	Histidine kinase
C9E41_RS10835	COG0643	Histidine kinase
C9E41_RS10840	COG0835	chemotaxis
C9E41_RS10845	COG0840	transmembrane signaling receptor activity
C9E41_RS10850	COG0840	transmembrane signaling receptor activity
C9E41_RS10855	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C9E41_RS10860	COG2201	protein-glutamate methylesterase activity
C9E41_RS10865	COG0745	RESPONSE REGULATOR receiver
C9E41_RS10875	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C9E41_RS10880	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C9E41_RS10890	COG3755	Protein conserved in bacteria
C9E41_RS10900	COG3102	Protein conserved in bacteria
C9E41_RS10910	COG3005	denitrification pathway
C9E41_RS10915	COG0243	molybdopterin cofactor binding
C9E41_RS10930	COG3788	relative of glutathione S-transferase, MAPEG superfamily
C9E41_RS10935	COG1801	Protein of unknown function DUF72
C9E41_RS10940	COG1335	isochorismatase
C9E41_RS10945	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C9E41_RS10950	COG0494	nUDIX hydrolase
C9E41_RS10955	COG0217	transcriptional regulatory protein
C9E41_RS10985	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C9E41_RS10995	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
C9E41_RS11000	COG0739	heme binding
C9E41_RS11005	COG1560	Kdo2-lipid A biosynthetic process
C9E41_RS11010	COG0469	pyruvate kinase activity
C9E41_RS11015	COG1737	Transcriptional regulator
C9E41_RS11020	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C9E41_RS11025	COG0129	dihydroxy-acid dehydratase activity
C9E41_RS11030	COG0800	Aldolase
C9E41_RS11035	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
C9E41_RS11040	COG3141	response to X-ray
C9E41_RS11050	COG2979	Protein of unknown function (DUF533)
C9E41_RS11055	COG1770	oligopeptidase
C9E41_RS11060	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C9E41_RS11065	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C9E41_RS11075	COG2372	response to copper ion
C9E41_RS11080	COG1276	copper resistance
C9E41_RS11090	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C9E41_RS11110	COG3008	intermembrane lipid transfer
C9E41_RS11115	COG2995	paraquat-inducible protein a
C9E41_RS11120	COG1956	GAF domain-containing protein
C9E41_RS11130	COG0793	Belongs to the peptidase S41A family
C9E41_RS11140	COG2814	Major facilitator Superfamily
C9E41_RS11145	COG1414	Transcriptional regulator
C9E41_RS11175	COG2226	methyltransferase
C9E41_RS11190	COG3716	PTS system mannose fructose sorbose family IID component
C9E41_RS11195	COG3715	PTS system
C9E41_RS11200	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9E41_RS11200	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C9E41_RS11205	COG1253	flavin adenine dinucleotide binding
C9E41_RS11210	COG2200	EAL domain
C9E41_RS11215	COG1760	l-serine dehydratase
C9E41_RS11225	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C9E41_RS11240	COG0251	oxidation-reduction process
C9E41_RS11245	COG1199	ATP-dependent helicase activity
C9E41_RS11250	COG1214	PFAM Peptidase M22, glycoprotease
C9E41_RS11255	COG3065	identical protein binding
C9E41_RS11260	COG0318	PFAM AMP-dependent synthetase and ligase
C9E41_RS11265	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
C9E41_RS11270	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C9E41_RS11275	COG4638	Rieske (2fe-2S)
C9E41_RS11280	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C9E41_RS11285	COG0473	3-isopropylmalate dehydrogenase activity
C9E41_RS11290	COG0583	DNA-binding transcription factor activity
C9E41_RS11295	COG1280	lysine exporter protein (LysE YggA)
C9E41_RS11300	COG3615	Tellurite resistance protein tehB
C9E41_RS11310	COG2261	transglycosylase associated protein
C9E41_RS11330	COG3042	response to heat
C9E41_RS11335	COG3189	MarR family transcriptional regulator
C9E41_RS11340	COG2807	transmembrane transport
C9E41_RS11345	COG2207	Transcriptional regulator
C9E41_RS11360	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C9E41_RS11365	COG2199	diguanylate cyclase activity
C9E41_RS11370	COG2199	diguanylate cyclase activity
C9E41_RS11380	COG2766	serine protein kinase
C9E41_RS11385	COG3713	MltA-interacting MipA family protein
C9E41_RS11390	COG0656	L-ascorbic acid biosynthetic process
C9E41_RS11395	COG0676	glucose-6-phosphate 1-epimerase activity
C9E41_RS11400	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C9E41_RS11410	COG3139	Protein of unknown function (DUF1315)
C9E41_RS11415	COG1063	alcohol dehydrogenase
C9E41_RS11420	COG2271	Major facilitator Superfamily
C9E41_RS11425	COG1063	alcohol dehydrogenase
C9E41_RS11430	COG0191	fructose-bisphosphate aldolase activity
C9E41_RS11435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C9E41_RS11440	COG0667	Aldo Keto reductase
C9E41_RS11445	COG1349	DNA-binding transcription factor activity
C9E41_RS11460	COG2814	Major facilitator Superfamily
C9E41_RS11465	COG1335	isochorismatase
C9E41_RS11470	COG0252	asparaginase activity
C9E41_RS11480	COG0616	signal peptide processing
C9E41_RS11485	COG0778	Nitroreductase
C9E41_RS11490	COG0709	Synthesizes selenophosphate from selenide and ATP
C9E41_RS11495	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C9E41_RS11505	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C9E41_RS11515	COG0494	nUDIX hydrolase
C9E41_RS11520	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C9E41_RS11525	COG2897	thiosulfate sulfurtransferase activity
C9E41_RS11530	COG4136	ATPase activity
C9E41_RS11535	COG4135	transport system, permease component
C9E41_RS11540	COG4134	Bacterial extracellular solute-binding protein
C9E41_RS11545	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C9E41_RS11550	COG0398	Pfam SNARE associated Golgi protein
C9E41_RS11560	COG0398	Pfam SNARE associated Golgi protein
C9E41_RS11565	COG0708	Exodeoxyribonuclease III
C9E41_RS11595	COG3678	ATP-independent chaperone mediated protein folding
C9E41_RS11605	COG0322	excinuclease ABC activity
C9E41_RS11615	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C9E41_RS11625	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C9E41_RS11630	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C9E41_RS11635	COG1447	Phosphotransferase system cellobiose-specific component IIA
C9E41_RS11640	COG1917	Cupin 2, conserved barrel domain protein
C9E41_RS11640	COG2169	Transcriptional regulator
C9E41_RS11645	COG1486	melibiose metabolic process
C9E41_RS11655	COG0753	catalase activity
C9E41_RS11670	COG1823	symporter activity
C9E41_RS11675	COG1988	membrane-bound metal-dependent
C9E41_RS11680	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C9E41_RS11690	COG3001	Fructosamine kinase
C9E41_RS11700	COG1105	Belongs to the carbohydrate kinase PfkB family
C9E41_RS11705	COG3137	Salt-induced outer membrane protein
C9E41_RS11750	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C9E41_RS11750	COG0072	phenylalanine-tRNA ligase activity
C9E41_RS11765	COG0386	Belongs to the glutathione peroxidase family
C9E41_RS11775	COG0791	NLP P60 protein
C9E41_RS11780	COG2200	EAL domain
C9E41_RS11790	COG4256	Hemin uptake protein
C9E41_RS11795	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C9E41_RS11805	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C9E41_RS11805	COG0574	Belongs to the PEP-utilizing enzyme family
C9E41_RS11810	COG0318	PFAM AMP-dependent synthetase and ligase
C9E41_RS11815	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C9E41_RS11820	COG0644	oxidoreductase
C9E41_RS11825	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C9E41_RS11830	COG2086	electron transfer activity
C9E41_RS11835	COG2207	Transcriptional regulator
C9E41_RS11835	COG1917	Cupin 2, conserved barrel domain protein
C9E41_RS11840	COG1960	acyl-CoA dehydrogenase activity
C9E41_RS11845	COG4670	ketone body catabolic process
C9E41_RS11860	COG2271	Major facilitator Superfamily
C9E41_RS11865	COG0738	Major facilitator superfamily
C9E41_RS11880	COG0628	permease
C9E41_RS11885	COG0277	FAD linked oxidase domain protein
C9E41_RS11885	COG0247	lactate metabolic process
C9E41_RS11890	COG2050	protein possibly involved in aromatic compounds catabolism
C9E41_RS11900	COG0316	Belongs to the HesB IscA family
C9E41_RS11905	COG0719	Fe-S assembly protein
C9E41_RS11910	COG0396	ATPase activity
C9E41_RS11915	COG0719	Fe-S assembly protein
C9E41_RS11930	COG1376	ErfK ybiS ycfS ynhG family protein
C9E41_RS11935	COG4238	major outer membrane lipoprotein
C9E41_RS11940	COG0469	pyruvate kinase activity
C9E41_RS11950	COG0437	4 iron, 4 sulfur cluster binding
C9E41_RS11955	COG2414	aldehyde ferredoxin oxidoreductase
C9E41_RS11965	COG0437	4 iron, 4 sulfur cluster binding
C9E41_RS11970	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
C9E41_RS11980	COG4529	Protein conserved in bacteria
C9E41_RS12000	COG3468	outer membrane autotransporter barrel domain protein
C9E41_RS12010	COG0307	riboflavin synthase, alpha
C9E41_RS12015	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C9E41_RS12020	COG2814	Major facilitator Superfamily
C9E41_RS12025	COG0583	DNA-binding transcription factor activity
C9E41_RS12040	COG2814	Major facilitator Superfamily
C9E41_RS12045	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C9E41_RS12050	COG0791	NLP P60 protein
C9E41_RS12055	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C9E41_RS12060	COG1201	RNA secondary structure unwinding
C9E41_RS12070	COG0346	lactoylglutathione lyase activity
C9E41_RS12075	COG1902	pentaerythritol trinitrate reductase activity
C9E41_RS12080	COG1309	transcriptional regulator
C9E41_RS12085	COG3313	Fe-S protein
C9E41_RS12090	COG4989	oxidoreductase activity
C9E41_RS12095	COG2032	superoxide dismutase activity
C9E41_RS12100	COG1289	transmembrane transporter activity
C9E41_RS12105	COG1566	PFAM secretion protein HlyD family protein
C9E41_RS12120	COG3133	Outer membrane lipoprotein
C9E41_RS12130	COG3895	Periplasmic Protein
C9E41_RS12145	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
C9E41_RS12150	COG0625	glutathione transferase activity
C9E41_RS12155	COG3104	oligopeptide transport
C9E41_RS12160	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C9E41_RS12170	COG4659	FMN binding
C9E41_RS12180	COG4656	Part of a membrane complex involved in electron transport
C9E41_RS12210	COG0673	inositol 2-dehydrogenase activity
C9E41_RS12220	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C9E41_RS12225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C9E41_RS12225	COG1263	PTS System
C9E41_RS12230	COG1609	Transcriptional regulator
C9E41_RS12235	COG1028	Short-chain dehydrogenase reductase Sdr
C9E41_RS12240	COG1309	transcriptional regulator
C9E41_RS12260	COG5339	Protein conserved in bacteria
C9E41_RS12265	COG1482	cell wall glycoprotein biosynthetic process
C9E41_RS12270	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C9E41_RS12270	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C9E41_RS12275	COG0114	fumarate hydratase activity
C9E41_RS12285	COG2205	protein histidine kinase activity
C9E41_RS12290	COG0745	RESPONSE REGULATOR receiver
C9E41_RS12295	COG3136	membrane protein required for alginate biosynthesis
C9E41_RS12305	COG0531	amino acid
C9E41_RS12315	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
C9E41_RS12320	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
C9E41_RS12325	COG0628	permease
C9E41_RS12345	COG3591	Belongs to the peptidase S1B family
C9E41_RS12360	COG2814	Major facilitator Superfamily
C9E41_RS12365	COG0583	DNA-binding transcription factor activity
C9E41_RS12370	COG1940	carbohydrate kinase activity
C9E41_RS12375	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C9E41_RS12385	COG3381	protein complex oligomerization
C9E41_RS12390	COG3302	dmso reductase anchor subunit
C9E41_RS12395	COG0437	4 iron, 4 sulfur cluster binding
C9E41_RS12400	COG0243	molybdopterin cofactor binding
C9E41_RS12405	COG0243	molybdopterin cofactor binding
C9E41_RS12420	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C9E41_RS12450	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C9E41_RS12505	COG1846	Transcriptional regulator
C9E41_RS12510	COG1484	DNA-dependent DNA replication
C9E41_RS12545	COG1403	HNH endonuclease
C9E41_RS12550	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C9E41_RS12605	COG3772	lysozyme
C9E41_RS12730	COG5301	cellulose 1,4-beta-cellobiosidase activity
C9E41_RS12780	COG4372	Transposase
C9E41_RS12785	COG3436	PFAM IS66 Orf2 family protein
C9E41_RS12805	COG0582	viral genome integration into host DNA
C9E41_RS12810	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C9E41_RS12870	COG1846	Transcriptional regulator
C9E41_RS12905	COG3111	PFAM Bacterial OB fold (BOF) protein
C9E41_RS12915	COG1403	HNH endonuclease
C9E41_RS12920	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C9E41_RS12935	COG2207	Transcriptional regulator
C9E41_RS12975	COG3772	lysozyme
C9E41_RS13010	COG4220	transposase activity
C9E41_RS13030	COG1030	water channel activity
C9E41_RS13115	COG5301	cellulose 1,4-beta-cellobiosidase activity
C9E41_RS13150	COG0477	Major facilitator Superfamily
C9E41_RS13155	COG0246	Mannitol dehydrogenase
C9E41_RS13165	COG1802	Transcriptional regulator
C9E41_RS13170	COG4221	oxidoreductase activity
C9E41_RS13175	COG0339	signal peptide processing
C9E41_RS13180	COG1546	Belongs to the CinA family
C9E41_RS13185	COG3111	PFAM Bacterial OB fold (BOF) protein
C9E41_RS13190	COG3706	GGDEF domain
C9E41_RS13210	COG2814	Major facilitator Superfamily
C9E41_RS13215	COG0697	spore germination
C9E41_RS13225	COG4977	sequence-specific DNA binding
C9E41_RS13230	COG1846	Transcriptional regulator
C9E41_RS13235	COG2095	MarC family integral membrane protein
C9E41_RS13240	COG2814	Major facilitator Superfamily
C9E41_RS13250	COG0583	DNA-binding transcription factor activity
C9E41_RS13255	COG1012	belongs to the aldehyde dehydrogenase family
C9E41_RS13260	COG2066	Belongs to the glutaminase family
C9E41_RS13270	COG2199	diguanylate cyclase activity
C9E41_RS13280	COG3781	membrane
C9E41_RS13295	COG1830	Aldolase
C9E41_RS13305	COG1172	Belongs to the binding-protein-dependent transport system permease family
C9E41_RS13310	COG1172	Belongs to the binding-protein-dependent transport system permease family
C9E41_RS13315	COG1129	ABC transporter
C9E41_RS13325	COG1070	Carbohydrate kinase
C9E41_RS13330	COG2911	Protein conserved in bacteria
C9E41_RS13330	COG3210	domain, Protein
C9E41_RS13355	COG3539	Fimbrial protein
C9E41_RS13365	COG3188	usher protein
C9E41_RS13370	COG3539	Fimbrial protein
C9E41_RS13375	COG3539	Fimbrial protein
C9E41_RS13380	COG3539	Fimbrial protein
C9E41_RS13385	COG0243	molybdopterin cofactor binding
C9E41_RS13395	COG2207	Transcriptional regulator
C9E41_RS13400	COG3119	arylsulfatase activity
C9E41_RS13405	COG0641	radical SAM
C9E41_RS13415	COG4178	(ABC) transporter
C9E41_RS13420	COG4771	TonB-dependent receptor
C9E41_RS13425	COG0612	Peptidase, M16
C9E41_RS13430	COG0076	glutamate decarboxylase activity
C9E41_RS13435	COG0531	amino acid
C9E41_RS13440	COG1649	PFAM Uncharacterised BCR, COG1649
C9E41_RS13445	COG3706	GGDEF domain
C9E41_RS13455	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
C9E41_RS13460	COG0747	negative chemotaxis
C9E41_RS13465	COG0601	transmembrane transport
C9E41_RS13470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C9E41_RS13475	COG0444	Belongs to the ABC transporter superfamily
C9E41_RS13480	COG4608	Belongs to the ABC transporter superfamily
C9E41_RS13485	COG1764	response to oxidative stress
C9E41_RS13505	COG1064	alcohol dehydrogenase
C9E41_RS13510	COG3093	addiction module antidote protein HigA
C9E41_RS13515	COG2864	formate dehydrogenase
C9E41_RS13520	COG0437	4 iron, 4 sulfur cluster binding
C9E41_RS13530	COG0697	spore germination
C9E41_RS13545	COG4886	Leucine-rich repeat (LRR) protein
C9E41_RS13550	COG4886	Leucine-rich repeat (LRR) protein
C9E41_RS13555	COG2223	nitrite transmembrane transporter activity
C9E41_RS13560	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C9E41_RS13565	COG1140	nitrate reductase beta subunit
C9E41_RS13570	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C9E41_RS13575	COG2181	nitrate reductase activity
C9E41_RS13580	COG0384	phenazine biosynthesis protein PhzF
C9E41_RS13590	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C9E41_RS13620	COG3209	COG3209 Rhs family protein
C9E41_RS13635	COG0625	glutathione transferase activity
C9E41_RS13640	COG1113	amino acid transport
C9E41_RS13645	COG3391	amine dehydrogenase activity
C9E41_RS13650	COG4772	TonB-dependent receptor
C9E41_RS13655	COG1802	Transcriptional regulator
C9E41_RS13660	COG2130	NADP-dependent
C9E41_RS13665	COG1247	-acetyltransferase
C9E41_RS13670	COG3238	Protein conserved in bacteria
C9E41_RS13695	COG1177	transmembrane transport
C9E41_RS13700	COG1176	ABC-type spermidine putrescine transport system, permease component I
C9E41_RS13705	COG3842	ATPase activity
C9E41_RS13710	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C9E41_RS13715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C9E41_RS13720	COG1598	PFAM Uncharacterised protein family UPF0150
C9E41_RS13725	COG1724	mRNA binding
C9E41_RS13735	COG0826	peptidase U32
C9E41_RS13740	COG1396	sequence-specific DNA binding
C9E41_RS13745	COG3135	benzoate transporter
C9E41_RS13755	COG0500	methyltransferase
C9E41_RS13760	COG1275	C4-dicarboxylate transporter malic acid transport protein
C9E41_RS13765	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C9E41_RS13775	COG2841	Protein conserved in bacteria
C9E41_RS13785	COG5383	Protein conserved in bacteria
C9E41_RS13790	COG0583	DNA-binding transcription factor activity
C9E41_RS13795	COG0840	transmembrane signaling receptor activity
C9E41_RS13810	COG3038	cytochrome b561
C9E41_RS13815	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C9E41_RS13820	COG1012	belongs to the aldehyde dehydrogenase family
C9E41_RS13825	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C9E41_RS13850	COG1643	Atp-dependent helicase
C9E41_RS13855	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C9E41_RS13860	COG2453	phosphatase
C9E41_RS13860	COG0671	phosphoesterase, PA-phosphatase related
C9E41_RS13865	COG2267	carboxylic ester hydrolase activity
C9E41_RS13870	COG4589	Belongs to the CDS family
C9E41_RS13875	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C9E41_RS13885	COG0667	Aldo Keto reductase
C9E41_RS13900	COG3784	Protein of unknown function (DUF1318)
C9E41_RS13910	COG2911	Protein conserved in bacteria
C9E41_RS13915	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C9E41_RS13920	COG3187	Heat shock protein
C9E41_RS13925	COG3042	response to heat
C9E41_RS13930	COG0674	pyruvate-flavodoxin oxidoreductase activity
C9E41_RS13930	COG1013	pyruvate-flavodoxin oxidoreductase activity
C9E41_RS13930	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
C9E41_RS13930	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C9E41_RS13940	COG0589	response to stress
C9E41_RS13965	COG5301	cellulose 1,4-beta-cellobiosidase activity
C9E41_RS13980	COG2032	superoxide dismutase activity
C9E41_RS14120	COG3772	lysozyme
C9E41_RS14220	COG1846	Transcriptional regulator
C9E41_RS14225	COG1484	DNA-dependent DNA replication
C9E41_RS14230	COG3756	Protein conserved in bacteria
C9E41_RS14285	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C9E41_RS14290	COG3723	Recombinational DNA repair protein, rece pathway
C9E41_RS14310	COG0582	viral genome integration into host DNA
C9E41_RS14320	COG0513	Belongs to the DEAD box helicase family
C9E41_RS14335	COG3706	GGDEF domain
C9E41_RS14340	COG2840	Smr protein MutS2
C9E41_RS14345	COG0583	DNA-binding transcription factor activity
C9E41_RS14350	COG1473	amidohydrolase
C9E41_RS14355	COG1473	amidohydrolase
C9E41_RS14375	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C9E41_RS14380	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C9E41_RS14385	COG0589	response to stress
C9E41_RS14390	COG3182	Iron-regulated membrane protein
C9E41_RS14395	COG0668	transmembrane transport
C9E41_RS14400	COG4166	transmembrane transport
C9E41_RS14405	COG0583	DNA-binding transcription factor activity
C9E41_RS14410	COG1073	alpha beta
C9E41_RS14420	COG0702	epimerase
C9E41_RS14425	COG2866	Carboxypeptidase
C9E41_RS14430	COG4948	Mandelate Racemase Muconate Lactonizing
C9E41_RS14435	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
C9E41_RS14440	COG3283	Transcriptional regulator of aromatic amino acids metabolism
C9E41_RS14450	COG3106	COG3106 Predicted ATPase
C9E41_RS14455	COG1609	Transcriptional regulator
C9E41_RS14465	COG3842	ATPase activity
C9E41_RS14470	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C9E41_RS14475	COG1554	hydrolase, family 65, central catalytic
C9E41_RS14480	COG0673	inositol 2-dehydrogenase activity
C9E41_RS14485	COG1082	Xylose isomerase domain protein TIM barrel
C9E41_RS14490	COG1063	alcohol dehydrogenase
C9E41_RS14495	COG0395	ABC-type sugar transport system, permease component
C9E41_RS14500	COG1175	transmembrane transport
C9E41_RS14515	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C9E41_RS14525	COG1983	PspC domain protein
C9E41_RS14535	COG1842	Phage shock protein A
C9E41_RS14540	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C9E41_RS14545	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C9E41_RS14550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C9E41_RS14555	COG1012	belongs to the aldehyde dehydrogenase family
C9E41_RS14560	COG1396	sequence-specific DNA binding
C9E41_RS14560	COG1917	Cupin 2, conserved barrel domain protein
C9E41_RS14565	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C9E41_RS14570	COG0174	glutamine synthetase
C9E41_RS14580	COG0531	amino acid
C9E41_RS14590	COG4166	transmembrane transport
C9E41_RS14595	COG4168	peptide transport system, permease
C9E41_RS14600	COG4171	peptide transport system, permease
C9E41_RS14605	COG4172	Belongs to the ABC transporter superfamily
C9E41_RS14610	COG4172	Belongs to the ABC transporter superfamily
C9E41_RS14615	COG2814	Major facilitator Superfamily
C9E41_RS14625	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C9E41_RS14630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C9E41_RS14640	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C9E41_RS14645	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C9E41_RS14645	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C9E41_RS14655	COG5001	Diguanylate cyclase
C9E41_RS14665	COG1349	DNA-binding transcription factor activity
C9E41_RS14675	COG0023	Translation Initiation Factor
C9E41_RS14685	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
C9E41_RS14690	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
C9E41_RS14695	COG0671	phosphoesterase, PA-phosphatase related
C9E41_RS14705	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C9E41_RS14725	COG0583	DNA-binding transcription factor activity
C9E41_RS14730	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C9E41_RS14740	COG0616	signal peptide processing
C9E41_RS14745	COG1028	Short-chain dehydrogenase reductase Sdr
C9E41_RS14750	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
C9E41_RS14755	COG1187	pseudouridine synthase activity
C9E41_RS14760	COG4907	membrane protein (DUF2207)
C9E41_RS14765	COG0009	L-threonylcarbamoyladenylate synthase
C9E41_RS14770	COG0613	PHP domain protein
C9E41_RS14780	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C9E41_RS14785	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C9E41_RS14785	COG0512	Glutamine amidotransferase of anthranilate synthase
C9E41_RS14790	COG0135	phosphoribosylanthranilate isomerase activity
C9E41_RS14790	COG0134	indole-3-glycerol-phosphate synthase activity
C9E41_RS14805	COG3729	General stress protein
C9E41_RS14810	COG3685	Protein conserved in bacteria
C9E41_RS14815	COG3685	Protein conserved in bacteria
C9E41_RS14870	COG3436	PFAM IS66 Orf2 family protein
C9E41_RS14875	COG4372	Transposase
C9E41_RS14905	COG5301	cellulose 1,4-beta-cellobiosidase activity
C9E41_RS15045	COG3772	lysozyme
C9E41_RS15095	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C9E41_RS15100	COG1403	HNH endonuclease
C9E41_RS15135	COG1846	Transcriptional regulator
C9E41_RS15165	COG1396	sequence-specific DNA binding
C9E41_RS15210	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C9E41_RS15220	COG0582	viral genome integration into host DNA
C9E41_RS15225	COG3047	cAMP biosynthetic process
C9E41_RS15245	COG1607	acyl-coa hydrolase
C9E41_RS15250	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
C9E41_RS15255	COG2350	Protein conserved in bacteria
C9E41_RS15260	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C9E41_RS15280	COG4608	Belongs to the ABC transporter superfamily
C9E41_RS15285	COG0444	Belongs to the ABC transporter superfamily
C9E41_RS15290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C9E41_RS15295	COG0601	transmembrane transport
C9E41_RS15300	COG4166	transmembrane transport
C9E41_RS15305	COG2095	MarC family integral membrane protein
C9E41_RS15310	COG1012	belongs to the aldehyde dehydrogenase family
C9E41_RS15310	COG1454	alcohol dehydrogenase
C9E41_RS15315	COG1435	thymidine kinase activity
C9E41_RS15325	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C9E41_RS15330	COG0745	RESPONSE REGULATOR receiver
C9E41_RS15335	COG1752	Esterase of the alpha-beta hydrolase superfamily
C9E41_RS15345	COG0788	formyltetrahydrofolate deformylase activity
C9E41_RS15375	COG2181	nitrate reductase activity
C9E41_RS15380	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C9E41_RS15385	COG1140	nitrate reductase beta subunit
C9E41_RS15390	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C9E41_RS15395	COG2223	nitrite transmembrane transporter activity
C9E41_RS15400	COG3850	Histidine kinase
C9E41_RS15405	COG2197	response regulator
C9E41_RS15410	COG4932	domain protein
C9E41_RS15415	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
C9E41_RS15420	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
C9E41_RS15425	COG4572	Cation transport regulator
C9E41_RS15430	COG0387	Pfam Sodium calcium exchanger
C9E41_RS15460	COG2912	Transglutaminase-like superfamily
C9E41_RS15465	COG3094	Invasion gene expression up-regulator, SirB
C9E41_RS15495	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C9E41_RS15500	COG0659	secondary active sulfate transmembrane transporter activity
C9E41_RS15515	COG0012	GTP binding
C9E41_RS15525	COG2376	Dihydroxyacetone kinase
C9E41_RS15530	COG1461	Dihydroxyacetone kinase
C9E41_RS15535	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
C9E41_RS15535	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9E41_RS15535	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C9E41_RS15545	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
C9E41_RS15555	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C9E41_RS15560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C9E41_RS15565	COG1120	ATPase activity
C9E41_RS15570	COG0500	methyltransferase
C9E41_RS15580	COG0157	Belongs to the NadC ModD family
C9E41_RS15595	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
C9E41_RS15610	COG1619	proteins homologs of microcin C7 resistance protein MccF
C9E41_RS15620	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C9E41_RS15630	COG2719	SpoVR family
C9E41_RS15645	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C9E41_RS15650	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C9E41_RS15655	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C9E41_RS15670	COG0179	Fumarylacetoacetate (FAA) hydrolase
C9E41_RS15695	COG2894	cell division
C9E41_RS15725	COG4571	Outer membrane protease
C9E41_RS15740	COG4372	Transposase
C9E41_RS15745	COG3436	PFAM IS66 Orf2 family protein
C9E41_RS15760	COG0500	methyltransferase
C9E41_RS15770	COG3729	General stress protein
C9E41_RS15775	COG3685	Protein conserved in bacteria
C9E41_RS15780	COG3685	Protein conserved in bacteria
C9E41_RS15785	COG3546	catalase activity
C9E41_RS15790	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C9E41_RS15795	COG5301	cellulose 1,4-beta-cellobiosidase activity
C9E41_RS15830	COG1196	nuclear chromosome segregation
C9E41_RS15880	COG1030	water channel activity
C9E41_RS15900	COG4220	transposase activity
C9E41_RS15915	COG5562	phage envelope protein
C9E41_RS15955	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C9E41_RS15980	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C9E41_RS15990	COG2076	Multidrug Resistance protein
C9E41_RS16015	COG0582	viral genome integration into host DNA
C9E41_RS16020	COG0538	isocitrate dehydrogenase activity
C9E41_RS16025	COG1187	pseudouridine synthase activity
C9E41_RS16035	COG0482	sulfurtransferase activity
C9E41_RS16045	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C9E41_RS16050	COG0745	RESPONSE REGULATOR receiver
C9E41_RS16055	COG2205	protein histidine kinase activity
C9E41_RS16070	COG1802	Transcriptional regulator
C9E41_RS16070	COG4626	Terminase
C9E41_RS16185	COG2850	peptidyl-arginine hydroxylation
C9E41_RS16195	COG3842	ATPase activity
C9E41_RS16405	COG3772	lysozyme
C9E41_RS16445	COG0484	heat shock protein binding
C9E41_RS16450	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C9E41_RS16455	COG1403	HNH endonuclease
C9E41_RS16510	COG1846	Transcriptional regulator
C9E41_RS16530	COG4197	protein conserved in bacteria, prophage-related
C9E41_RS16560	COG0582	viral genome integration into host DNA
C9E41_RS16565	COG1177	transmembrane transport
C9E41_RS16570	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C9E41_RS16575	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C9E41_RS16585	COG4591	ABC-type transport system involved in lipoprotein release permease component
C9E41_RS16590	COG1136	(ABC) transporter
C9E41_RS16595	COG4591	ABC-type transport system involved in lipoprotein release permease component
C9E41_RS16600	COG4763	Acyl-transferase
C9E41_RS16605	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C9E41_RS16610	COG1388	LysM domain
C9E41_RS16610	COG1376	ErfK ybiS ycfS ynhG family protein
C9E41_RS16620	COG1309	transcriptional regulator
C9E41_RS16625	COG3134	Outer membrane lipoprotein
C9E41_RS16630	COG1252	NADH dehydrogenase
C9E41_RS16645	COG0510	thiamine kinase activity
C9E41_RS16650	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
C9E41_RS16655	COG5633	Lipoprotein
C9E41_RS16660	COG0537	adenosine 5'-monophosphoramidase activity
C9E41_RS16670	COG4773	Receptor
C9E41_RS16675	COG1263	PTS System
C9E41_RS16675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C9E41_RS16680	COG0084	hydrolase, TatD family'
C9E41_RS16685	COG0470	DNA polymerase III
C9E41_RS16695	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C9E41_RS16700	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C9E41_RS16705	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C9E41_RS16715	COG1028	Short-chain dehydrogenase reductase Sdr
C9E41_RS16720	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C9E41_RS16740	COG1399	metal-binding, possibly nucleic acid-binding protein
C9E41_RS16745	COG0424	maF-like protein
C9E41_RS16750	COG0564	pseudouridine synthase activity
C9E41_RS16755	COG1530	ribonuclease E activity
C9E41_RS16760	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C9E41_RS16765	COG1256	bacterial-type flagellum assembly
C9E41_RS16770	COG3951	Flagellar rod assembly protein muramidase FlgJ
C9E41_RS16770	COG1705	Flagellar rod assembly protein muramidase FlgJ
C9E41_RS16785	COG4786	Flagellar basal body rod
C9E41_RS16790	COG4787	bacterial-type flagellum-dependent cell motility
C9E41_RS16795	COG1749	Flagellar hook protein flgE
C9E41_RS16800	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C9E41_RS16805	COG1558	bacterial-type flagellum-dependent cell motility
C9E41_RS16810	COG1815	bacterial-type flagellum-dependent cell motility
C9E41_RS16815	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
C9E41_RS16820	COG2747	anti-sigma28 factor FlgM
C9E41_RS16825	COG3418	PFAM FlgN family protein
C9E41_RS16830	COG0728	peptidoglycan biosynthetic process
C9E41_RS16835	COG0673	inositol 2-dehydrogenase activity
C9E41_RS16845	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C9E41_RS16855	COG2999	glutathione oxidoreductase activity
C9E41_RS16890	COG3038	cytochrome b561
C9E41_RS16895	COG2353	YceI-like domain
C9E41_RS16905	COG1560	Kdo2-lipid A biosynthetic process
C9E41_RS16920	COG5645	(Lipo)protein
C9E41_RS16925	COG2943	transferase activity, transferring hexosyl groups
C9E41_RS16940	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C9E41_RS16945	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C9E41_RS16970	COG2197	response regulator
C9E41_RS16985	COG1462	curli production assembly transport component CsgG
C9E41_RS16995	COG3381	protein complex oligomerization
C9E41_RS17045	COG2003	Belongs to the UPF0758 family
C9E41_RS17080	COG3468	outer membrane autotransporter barrel domain protein
C9E41_RS17130	COG1475	DNA binding
C9E41_RS17135	COG3969	phosphoadenosine phosphosulfate
C9E41_RS17140	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
C9E41_RS17150	COG2831	hemolysin activation secretion protein
C9E41_RS17255	COG4771	TonB-dependent receptor
C9E41_RS17320	COG1358	cellular component organization or biogenesis
C9E41_RS17355	COG4372	Transposase
C9E41_RS17360	COG3436	PFAM IS66 Orf2 family protein
C9E41_RS17405	COG0254	rRNA binding
C9E41_RS17450	COG0829	nickel cation binding
C9E41_RS17460	COG2194	sulfuric ester hydrolase activity
C9E41_RS17465	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C9E41_RS17510	COG3436	PFAM IS66 Orf2 family protein
C9E41_RS17515	COG4372	Transposase
C9E41_RS17555	COG4983	Phage plasmid primase, P4 family domain protein
C9E41_RS17585	COG0582	viral genome integration into host DNA
C9E41_RS17635	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C9E41_RS17640	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C9E41_RS17650	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C9E41_RS17660	COG0736	holo-[acyl-carrier-protein] synthase activity
C9E41_RS17665	COG2831	hemolysin activation secretion protein
C9E41_RS17670	COG3210	domain, Protein
C9E41_RS17680	COG3539	Fimbrial protein
C9E41_RS17690	COG3188	usher protein
C9E41_RS17700	COG3121	Chaperone
C9E41_RS17705	COG1028	Short-chain dehydrogenase reductase Sdr
C9E41_RS17710	COG3710	Transcriptional regulator
C9E41_RS17720	COG2200	EAL domain
C9E41_RS17725	COG3706	GGDEF domain
C9E41_RS17730	COG0457	Tetratricopeptide repeat
C9E41_RS17735	COG0726	polysaccharide deacetylase
C9E41_RS17735	COG1649	PFAM Uncharacterised BCR, COG1649
C9E41_RS17740	COG1215	transferase activity, transferring glycosyl groups
C9E41_RS17745	COG3658	cytochrome
C9E41_RS17750	COG1702	phosphate starvation-inducible protein PhoH
C9E41_RS17755	COG2837	iron assimilation
C9E41_RS17760	COG2822	iron ion transport
C9E41_RS17775	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C9E41_RS17785	COG0506	proline dehydrogenase activity
C9E41_RS17785	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C9E41_RS17785	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C9E41_RS17790	COG1309	transcriptional regulator
C9E41_RS17830	COG2233	PERMEase
C9E41_RS17835	COG3729	General stress protein
C9E41_RS17850	COG3561	AntA/AntB antirepressor
C9E41_RS17890	COG3111	PFAM Bacterial OB fold (BOF) protein
C9E41_RS18065	COG3772	lysozyme
C9E41_RS18140	COG0305	Participates in initiation and elongation during chromosome replication
C9E41_RS18285	COG0582	viral genome integration into host DNA
C9E41_RS18295	COG3561	AntA/AntB antirepressor
C9E41_RS18335	COG3111	PFAM Bacterial OB fold (BOF) protein
C9E41_RS18510	COG3772	lysozyme
C9E41_RS18585	COG0305	Participates in initiation and elongation during chromosome replication
C9E41_RS18730	COG0582	viral genome integration into host DNA
C9E41_RS18770	COG0243	molybdopterin cofactor binding
C9E41_RS18775	COG3005	denitrification pathway
C9E41_RS18780	COG0745	RESPONSE REGULATOR receiver
C9E41_RS18785	COG1879	ABC-type sugar transport system periplasmic component
C9E41_RS18790	COG2205	protein histidine kinase activity
C9E41_RS18790	COG2198	Histidine kinase
C9E41_RS18790	COG0784	Response regulator, receiver
C9E41_RS18795	COG0348	domain, Protein
C9E41_RS18815	COG1278	Cold shock
C9E41_RS18820	COG1278	Cold shock
C9E41_RS18840	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C9E41_RS18845	COG1596	polysaccharide export
C9E41_RS18850	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C9E41_RS18855	COG0489	protein tyrosine kinase activity
C9E41_RS18855	COG3206	protein involved in exopolysaccharide biosynthesis
C9E41_RS18870	COG1294	oxidase, subunit
C9E41_RS18875	COG1271	oxidase subunit
C9E41_RS18880	COG1773	rubredoxin
C9E41_RS18885	COG1999	signal sequence binding
C9E41_RS18890	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C9E41_RS18895	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
C9E41_RS18900	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
C9E41_RS18905	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
C9E41_RS18930	COG5301	cellulose 1,4-beta-cellobiosidase activity
C9E41_RS18945	COG2032	superoxide dismutase activity
C9E41_RS19025	COG4220	transposase activity
C9E41_RS19030	COG4372	Transposase
C9E41_RS19035	COG3436	PFAM IS66 Orf2 family protein
C9E41_RS19070	COG3772	lysozyme
C9E41_RS19130	COG2207	Transcriptional regulator
C9E41_RS19150	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C9E41_RS19155	COG1403	HNH endonuclease
C9E41_RS19195	COG1846	Transcriptional regulator
C9E41_RS19200	COG1484	DNA-dependent DNA replication
C9E41_RS19275	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C9E41_RS19290	COG0670	Belongs to the BI1 family
C9E41_RS19295	COG2920	part of a sulfur-relay system
C9E41_RS19300	COG1254	Belongs to the acylphosphatase family
C9E41_RS19315	COG1832	CoA-binding protein
C9E41_RS19330	COG0210	DNA helicase
C9E41_RS19335	COG3304	Inner membrane component domain
C9E41_RS19340	COG1289	transmembrane transporter activity
C9E41_RS19345	COG3070	regulator of competence-specific genes
C9E41_RS19355	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
C9E41_RS19355	COG2885	chlorophyll binding
C9E41_RS19365	COG1067	ATP-dependent peptidase activity
C9E41_RS19375	COG3130	regulation of translation
C9E41_RS19380	COG3009	Protein conserved in bacteria
C9E41_RS19385	COG3008	intermembrane lipid transfer
C9E41_RS19385	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C9E41_RS19390	COG2995	paraquat-inducible protein a
C9E41_RS19395	COG0488	(ABC) transporter
C9E41_RS19405	COG0633	Ferredoxin
C9E41_RS19405	COG3217	Mosc domain protein beta barrel domain protein
C9E41_RS19425	COG3539	Fimbrial protein
C9E41_RS19430	COG3539	Fimbrial protein
C9E41_RS19440	COG3539	Fimbrial protein
C9E41_RS19450	COG3121	Chaperone
C9E41_RS19455	COG3539	Fimbrial protein
C9E41_RS19460	COG0431	NADPH-dependent FMN reductase
C9E41_RS19465	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C9E41_RS19475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C9E41_RS19480	COG1116	anion transmembrane transporter activity
C9E41_RS19485	COG0308	aminopeptidase N
C9E41_RS19495	COG0017	Asparaginyl-tRNA synthetase
C9E41_RS19505	COG1448	Aminotransferase
C9E41_RS19510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C9E41_RS19515	COG3108	Peptidase M15
C9E41_RS19520	COG2989	Protein conserved in bacteria
C9E41_RS19530	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
C9E41_RS19540	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C9E41_RS19545	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C9E41_RS19550	COG3173	Aminoglycoside phosphotransferase
C9E41_RS19565	COG3214	Protein conserved in bacteria
C9E41_RS19575	COG1132	(ABC) transporter
C9E41_RS19580	COG0658	competence protein
C9E41_RS19580	COG2333	competence protein COMEC
C9E41_RS19590	COG0539	negative regulation of cytoplasmic translation
C9E41_RS19600	COG0501	Belongs to the peptidase M48B family
C9E41_RS19615	COG2323	membrane
C9E41_RS19620	COG1944	ATP diphosphatase activity
C9E41_RS19625	COG2116	formate transmembrane transporter activity
C9E41_RS19630	COG1882	Formate acetyltransferase
C9E41_RS19635	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C9E41_RS19645	COG0531	amino acid
C9E41_RS19655	COG1335	isochorismatase
C9E41_RS19660	COG3302	dmso reductase anchor subunit
C9E41_RS19665	COG0437	4 iron, 4 sulfur cluster binding
C9E41_RS19670	COG0243	molybdopterin cofactor binding
C9E41_RS19680	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C9E41_RS19690	COG1178	ABC-type Fe3 transport system permease component
C9E41_RS19690	COG1674	ftsk spoiiie
C9E41_RS19695	COG1522	sequence-specific DNA binding
C9E41_RS19700	COG0492	ferredoxin-NADP+ reductase activity
C9E41_RS19705	COG4988	ABC transporter
C9E41_RS19710	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C9E41_RS19730	COG0542	response to heat
C9E41_RS19740	COG1278	Cold shock
C9E41_RS19745	COG0577	efflux transmembrane transporter activity
C9E41_RS19745	COG1136	(ABC) transporter
C9E41_RS19750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C9E41_RS19755	COG2990	Protein conserved in bacteria
C9E41_RS19760	COG3593	DNA synthesis involved in DNA repair
C9E41_RS19765	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C9E41_RS19775	COG2431	L-lysine efflux transmembrane transporter activity
C9E41_RS19785	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C9E41_RS19790	COG0028	Belongs to the TPP enzyme family
C9E41_RS19795	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
C9E41_RS19800	COG0702	epimerase
C9E41_RS19805	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C9E41_RS19810	COG3023	N-Acetylmuramoyl-L-alanine amidase
C9E41_RS19845	COG1126	abc transporter atp-binding protein
C9E41_RS19850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9E41_RS19855	COG4215	(ABC) transporter
C9E41_RS19860	COG4160	amino acid transport
C9E41_RS19865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9E41_RS19895	COG1177	transmembrane transport
C9E41_RS19900	COG1176	ABC-type spermidine putrescine transport system, permease component I
C9E41_RS19905	COG3842	ATPase activity
C9E41_RS19910	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C9E41_RS19925	COG0778	Nitroreductase
C9E41_RS19935	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C9E41_RS19950	COG3226	Transcriptional regulator
C9E41_RS19955	COG0738	Major facilitator superfamily
C9E41_RS19960	COG0561	phosphatase activity
C9E41_RS19970	COG2814	Major facilitator Superfamily
C9E41_RS19975	COG0671	phosphoesterase, PA-phosphatase related
C9E41_RS19980	COG1349	DNA-binding transcription factor activity
C9E41_RS19985	COG1686	Belongs to the peptidase S11 family
C9E41_RS19990	COG0625	glutathione transferase activity
C9E41_RS19995	COG2133	pyrroloquinoline quinone binding
C9E41_RS20020	COG2199	diguanylate cyclase activity
C9E41_RS20025	COG2200	EAL domain
C9E41_RS20035	COG0601	transmembrane transport
C9E41_RS20040	COG0747	negative chemotaxis
C9E41_RS20045	COG4172	Belongs to the ABC transporter superfamily
C9E41_RS20055	COG0303	'Molybdopterin
C9E41_RS20060	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C9E41_RS20065	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C9E41_RS20070	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C9E41_RS20080	COG0561	phosphatase activity
C9E41_RS20090	COG0488	(ABC) transporter
C9E41_RS20095	COG1376	ErfK ybiS ycfS ynhG family protein
C9E41_RS20100	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C9E41_RS20105	COG1321	iron dependent repressor
C9E41_RS20115	COG2194	sulfuric ester hydrolase activity
C9E41_RS20120	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
C9E41_RS20130	COG5006	permease, DMT superfamily
C9E41_RS20140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9E41_RS20145	COG0765	amino acid transport
C9E41_RS20150	COG1126	abc transporter atp-binding protein
C9E41_RS20155	COG0668	transmembrane transport
C9E41_RS20170	COG4774	siderophore transport
C9E41_RS20180	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C9E41_RS20190	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
C9E41_RS20195	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C9E41_RS20200	COG1199	ATP-dependent helicase activity
C9E41_RS20210	COG0513	Belongs to the DEAD box helicase family
C9E41_RS20215	COG1309	transcriptional regulator
C9E41_RS20225	COG1131	(ABC) transporter
C9E41_RS20230	COG0842	Transport permease protein
C9E41_RS20235	COG0842	Transport permease protein
C9E41_RS20245	COG3568	Endonuclease Exonuclease Phosphatase
C9E41_RS20250	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C9E41_RS20255	COG0392	lysyltransferase activity
C9E41_RS20260	COG0670	Belongs to the BI1 family
C9E41_RS20265	COG0670	Belongs to the BI1 family
C9E41_RS20270	COG0314	molybdopterin synthase activity
C9E41_RS20275	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C9E41_RS20285	COG0521	Mo-molybdopterin cofactor biosynthetic process
C9E41_RS20295	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C9E41_RS20305	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C9E41_RS20310	COG2226	methyltransferase
C9E41_RS20325	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C9E41_RS20330	COG1881	PFAM PEBP family protein
C9E41_RS20375	COG5301	cellulose 1,4-beta-cellobiosidase activity
C9E41_RS20450	COG0740	serine-type endopeptidase activity
C9E41_RS20495	COG3772	lysozyme
C9E41_RS20610	COG0582	viral genome integration into host DNA
C9E41_RS20615	COG4677	pectinesterase activity
C9E41_RS20620	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C9E41_RS20625	COG0471	metal ion transport
C9E41_RS20630	COG2828	Protein conserved in bacteria
C9E41_RS20635	COG0583	DNA-binding transcription factor activity
C9E41_RS20645	COG0561	phosphatase activity
C9E41_RS20655	COG4149	molybdate abc transporter
C9E41_RS20660	COG0725	ABC transporter, periplasmic molybdate-binding protein
C9E41_RS20670	COG3585	molybdate ion transport
C9E41_RS20670	COG2005	Transcriptional regulator
C9E41_RS20675	COG1119	ATPase activity
C9E41_RS20680	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C9E41_RS20685	COG1085	galactose-1-phosphate uridylyltransferase
C9E41_RS20695	COG2017	converts alpha-aldose to the beta-anomer
C9E41_RS20705	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C9E41_RS20715	COG1230	cation diffusion facilitator family transporter
C9E41_RS20720	COG3201	nicotinamide mononucleotide transporter
C9E41_RS20725	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
C9E41_RS20760	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
C9E41_RS20765	COG2885	chlorophyll binding
C9E41_RS20775	COG3064	Membrane
C9E41_RS20780	COG0848	biopolymer transport protein
C9E41_RS20785	COG0811	peptide transport
C9E41_RS20790	COG0824	Thioesterase
C9E41_RS20795	COG3790	cyd operon protein YbgE
C9E41_RS20800	COG4890	Cyd operon protein YbgT
C9E41_RS20805	COG1294	oxidase, subunit
C9E41_RS20810	COG1271	oxidase subunit
C9E41_RS20825	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C9E41_RS20835	COG4865	methylaspartate mutase activity
C9E41_RS20840	COG3799	methylaspartate ammonia-lyase activity
C9E41_RS20855	COG1301	dicarboxylic acid transport
C9E41_RS20860	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C9E41_RS20860	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C9E41_RS20865	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
C9E41_RS20870	COG0583	DNA-binding transcription factor activity
C9E41_RS20885	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C9E41_RS20895	COG0508	dehydrogenase complex catalyzes the overall conversion of
C9E41_RS20900	COG0567	Dehydrogenase, E1 component
C9E41_RS20905	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C9E41_RS20910	COG1053	succinate dehydrogenase
C9E41_RS20915	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
C9E41_RS20920	COG2009	succinate dehydrogenase
C9E41_RS20930	COG0372	Belongs to the citrate synthase family
C9E41_RS20935	COG3539	Fimbrial protein
C9E41_RS20940	COG3188	usher protein
C9E41_RS20945	COG3188	usher protein
C9E41_RS20950	COG3121	Chaperone
C9E41_RS20955	COG3539	Fimbrial protein
C9E41_RS20960	COG3180	Ammonia monooxygenase
C9E41_RS20965	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C9E41_RS20975	COG1984	allophanate hydrolase subunit 2
C9E41_RS20980	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C9E41_RS20985	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C9E41_RS20990	COG3104	oligopeptide transport
C9E41_RS20995	COG0415	Belongs to the DNA photolyase family
C9E41_RS21000	COG3272	Protein of unknown function (DUF1722)
C9E41_RS21030	COG3209	COG3209 Rhs family protein
C9E41_RS21060	COG2205	protein histidine kinase activity
C9E41_RS21065	COG0745	RESPONSE REGULATOR receiver
C9E41_RS21080	COG1982	Orn Lys Arg decarboxylase major
C9E41_RS21085	COG0531	amino acid
C9E41_RS21090	COG0033	Phosphoglucomutase
C9E41_RS21095	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
C9E41_RS21100	COG0596	Alpha beta hydrolase
C9E41_RS21110	COG0716	FMN binding
C9E41_RS21120	COG0735	belongs to the Fur family
C9E41_RS21145	COG2190	(PTS) system
C9E41_RS21145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C9E41_RS21145	COG1263	PTS System
C9E41_RS21155	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C9E41_RS21160	COG1846	Transcriptional regulator
C9E41_RS21160	COG1940	carbohydrate kinase activity
C9E41_RS21165	COG0647	UMP catabolic process
C9E41_RS21170	COG0367	asparagine synthase
C9E41_RS21210	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C9E41_RS21220	COG1702	phosphate starvation-inducible protein PhoH
C9E41_RS21230	COG4535	Mg2 and Co2 transporter CorC
C9E41_RS21235	COG0815	Transfers the fatty acyl group on membrane lipoproteins
C9E41_RS21240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9E41_RS21245	COG0765	amino acid transport
C9E41_RS21250	COG0765	amino acid transport
C9E41_RS21255	COG1126	abc transporter atp-binding protein
C9E41_RS21265	COG0443	Heat shock 70 kDa protein
C9E41_RS21280	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C9E41_RS21285	COG2214	Heat shock protein DnaJ domain protein
C9E41_RS21300	COG2888	peptidyl-tyrosine sulfation
C9E41_RS21315	COG1466	dna polymerase III delta subunit
C9E41_RS21325	COG0406	alpha-ribazole phosphatase activity
C9E41_RS21330	COG0799	negative regulation of ribosome biogenesis
C9E41_RS21340	COG0768	penicillin binding
C9E41_RS21345	COG0772	Belongs to the SEDS family
C9E41_RS21350	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C9E41_RS21355	COG1686	Belongs to the peptidase S11 family
C9E41_RS21370	COG0583	DNA-binding transcription factor activity
C9E41_RS21380	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C9E41_RS21385	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C9E41_RS21405	COG3069	C4-dicarboxylate transmembrane transporter activity
C9E41_RS21410	COG4565	transcriptional regulatory protein
C9E41_RS21415	COG3290	protein histidine kinase activity
C9E41_RS21420	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
C9E41_RS21430	COG2301	Belongs to the HpcH HpaI aldolase family
C9E41_RS21435	COG3051	citrate lyase alpha subunit
C9E41_RS21445	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
C9E41_RS21450	COG0471	metal ion transport
C9E41_RS21455	COG3719	Belongs to the RNase T2 family
C9E41_RS21460	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C9E41_RS21465	COG1063	alcohol dehydrogenase
C9E41_RS21470	COG0589	response to stress
C9E41_RS21475	COG3634	alkyl hydroperoxide reductase activity
C9E41_RS21480	COG0450	alkyl hydroperoxide reductase
C9E41_RS21485	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C9E41_RS21490	COG0583	DNA-binding transcription factor activity
C9E41_RS21495	COG3969	phosphoadenosine phosphosulfate
C9E41_RS21500	COG1475	DNA binding
C9E41_RS21505	COG0436	Aminotransferase
C9E41_RS21510	COG0371	Dehydrogenase
C9E41_RS21515	COG2879	small protein
C9E41_RS21520	COG1966	Carbon starvation protein
C9E41_RS21530	COG1028	Short-chain dehydrogenase reductase Sdr
C9E41_RS21535	COG3433	isochorismatase activity
C9E41_RS21535	COG1535	isochorismatase
C9E41_RS21540	COG1021	2,3-dihydroxybenzoate-AMP ligase
C9E41_RS21545	COG1169	isochorismate synthase
C9E41_RS21550	COG4592	Periplasmic binding protein
C9E41_RS21560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C9E41_RS21565	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C9E41_RS21570	COG1120	ATPase activity
C9E41_RS21575	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
C9E41_RS21580	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
C9E41_RS21580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9E41_RS21585	COG3251	PFAM MbtH domain protein
C9E41_RS21590	COG2382	esterase
C9E41_RS21595	COG4771	TonB-dependent receptor
C9E41_RS21600	COG2977	Belongs to the P-Pant transferase superfamily
C9E41_RS21635	COG2315	Protein conserved in bacteria
C9E41_RS21640	COG0778	Nitroreductase
C9E41_RS21645	COG0668	transmembrane transport
C9E41_RS21650	COG1113	amino acid transport
C9E41_RS21655	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C9E41_RS21660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C9E41_RS21665	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C9E41_RS21670	COG1538	Outer membrane efflux protein
C9E41_RS21675	COG0745	RESPONSE REGULATOR receiver
C9E41_RS21680	COG5002	protein histidine kinase activity
C9E41_RS21695	COG4104	PAAR repeat-containing protein
C9E41_RS21695	COG3209	COG3209 Rhs family protein
C9E41_RS21710	COG3209	COG3209 Rhs family protein
C9E41_RS21710	COG4104	PAAR repeat-containing protein
C9E41_RS21720	COG5433	transposase activity
C9E41_RS21725	COG1215	transferase activity, transferring glycosyl groups
C9E41_RS21730	COG4783	chaperone-mediated protein folding
C9E41_RS21740	COG2207	Transcriptional regulator
C9E41_RS21750	COG2197	response regulator
C9E41_RS21755	COG3539	Fimbrial protein
C9E41_RS21760	COG3539	Fimbrial protein
C9E41_RS21765	COG3188	usher protein
C9E41_RS21770	COG3121	Chaperone
C9E41_RS21775	COG3539	Fimbrial protein
C9E41_RS21785	COG2501	S4 domain
C9E41_RS21790	COG1988	membrane-bound metal-dependent
C9E41_RS21800	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C9E41_RS21810	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C9E41_RS21815	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C9E41_RS21820	COG0549	Belongs to the carbamate kinase family
C9E41_RS21830	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C9E41_RS21835	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C9E41_RS21840	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
C9E41_RS21845	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C9E41_RS21850	COG3257	ureidoglycine aminohydrolase activity
C9E41_RS21855	COG1929	Belongs to the glycerate kinase type-1 family
C9E41_RS21860	COG2233	PERMEase
C9E41_RS21870	COG1953	Uracil, thiamine, allantoin
C9E41_RS21875	COG2084	Dehydrogenase
C9E41_RS21880	COG3622	Belongs to the hyi family
C9E41_RS21885	COG3960	tartronate-semialdehyde synthase activity
C9E41_RS21890	COG1414	Transcriptional regulator
C9E41_RS21900	COG0583	DNA-binding transcription factor activity
C9E41_RS21920	COG3209	COG3209 Rhs family protein
C9E41_RS21925	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
C9E41_RS21930	COG4181	ATPase activity
C9E41_RS21935	COG2755	lipolytic protein G-D-S-L family
C9E41_RS21940	COG0300	oxidoreductase activity
C9E41_RS21945	COG3118	belongs to the thioredoxin family
C9E41_RS21950	COG0390	transport system, permease component
C9E41_RS21955	COG4619	ABC transporter
C9E41_RS21960	COG0330	HflC and HflK could
C9E41_RS21965	COG1585	Membrane protein implicated in regulation of membrane protease activity
C9E41_RS21990	COG0789	Transcriptional regulator
C9E41_RS22015	COG0531	amino acid
C9E41_RS22020	COG2066	Belongs to the glutaminase family
C9E41_RS22025	COG2217	Heavy metal translocating P-type atpase
C9E41_RS22030	COG3093	addiction module antidote protein HigA
C9E41_RS22040	COG3735	TraB family
C9E41_RS22045	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C9E41_RS22050	COG0737	Belongs to the 5'-nucleotidase family
C9E41_RS22055	COG2223	nitrite transmembrane transporter activity
C9E41_RS22060	COG4651	solute:proton antiporter activity
C9E41_RS22060	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C9E41_RS22065	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C9E41_RS22100	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C9E41_RS22110	COG2832	Protein of unknown function (DUF454)
C9E41_RS22115	COG3923	Primosomal replication protein n
C9E41_RS22125	COG3264	Mechanosensitive ion channel
C9E41_RS22125	COG1196	nuclear chromosome segregation
C9E41_RS22130	COG1309	transcriptional regulator
C9E41_RS22135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C9E41_RS22140	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C9E41_RS22155	COG0110	maltose O-acetyltransferase activity
C9E41_RS22165	COG4943	cyclic-guanylate-specific phosphodiesterase activity
C9E41_RS22170	COG5507	3-demethylubiquinone-9 3-methyltransferase
C9E41_RS22180	COG3695	enzyme binding
C9E41_RS22185	COG3126	Type III secretion system lipoprotein chaperone (YscW)
C9E41_RS22190	COG1946	Acyl-CoA thioesterase
C9E41_RS22195	COG0004	ammonium transporteR
C9E41_RS22200	COG0347	Belongs to the P(II) protein family
C9E41_RS22205	COG1132	(ABC) transporter
C9E41_RS22210	COG1132	(ABC) transporter
C9E41_RS22215	COG1522	sequence-specific DNA binding
C9E41_RS22225	COG4533	DNA binding
C9E41_RS22235	COG0824	Thioesterase
C9E41_RS22240	COG1555	photosystem II stabilization
C9E41_RS22245	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C9E41_RS22250	COG0776	regulation of translation
C9E41_RS22255	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C9E41_RS22275	COG0271	Belongs to the BolA IbaG family
C9E41_RS22280	COG3056	Lipoprotein
C9E41_RS22285	COG2223	nitrite transmembrane transporter activity
C9E41_RS22290	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C9E41_RS22295	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C9E41_RS22300	COG1845	cytochrome c oxidase, subunit III
C9E41_RS22305	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C9E41_RS22315	COG2814	Major facilitator Superfamily
C9E41_RS22325	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C9E41_RS22330	COG0693	protein deglycase activity
C9E41_RS22345	COG0142	geranyltranstransferase activity
C9E41_RS22355	COG0667	Aldo Keto reductase
C9E41_RS22365	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C9E41_RS22370	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C9E41_RS22385	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C9E41_RS22385	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C9E41_RS22395	COG4238	major outer membrane lipoprotein
C9E41_RS22400	COG3248	Nucleoside-binding outer membrane protein
C9E41_RS22405	COG1403	HNH endonuclease
C9E41_RS22415	COG3609	addiction module antidote protein, CC2985 family
C9E41_RS22425	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C9E41_RS22430	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C9E41_RS22435	COG1862	Preprotein translocase
C9E41_RS22460	COG0366	Alpha amylase catalytic
C9E41_RS22465	COG1113	amino acid transport
C9E41_RS22470	COG1114	Component of the transport system for branched-chain amino acids
C9E41_RS22475	COG5002	protein histidine kinase activity
C9E41_RS22480	COG0745	RESPONSE REGULATOR receiver
C9E41_RS22485	COG0420	3'-5' exonuclease activity
C9E41_RS22490	COG0419	ATPase involved in DNA repair
C9E41_RS22495	COG2814	Major facilitator Superfamily
C9E41_RS22500	COG1940	carbohydrate kinase activity
C9E41_RS22525	COG4126	flavin adenine dinucleotide binding
C9E41_RS22545	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C9E41_RS22550	COG3706	GGDEF domain
C9E41_RS22560	COG1785	Belongs to the alkaline phosphatase family
C9E41_RS22570	COG1181	Belongs to the D-alanine--D-alanine ligase family
C9E41_RS22590	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
C9E41_RS22595	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C9E41_RS22600	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C9E41_RS22605	COG3468	outer membrane autotransporter barrel domain protein
C9E41_RS22610	COG0113	porphobilinogen synthase activity
C9E41_RS22615	COG2175	clavaminate synthase activity
C9E41_RS22620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C9E41_RS22625	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
C9E41_RS22630	COG4521	taurine ABC transporter
C9E41_RS22645	COG2271	Major facilitator Superfamily
C9E41_RS22650	COG1840	ABC-type Fe3 transport system, periplasmic component
C9E41_RS22660	COG3842	ATPase activity
C9E41_RS22675	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
C9E41_RS22680	COG3122	Protein conserved in bacteria
C9E41_RS22685	COG2814	Major facilitator Superfamily
C9E41_RS22690	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C9E41_RS22705	COG0596	Alpha beta hydrolase
C9E41_RS22720	COG1414	Transcriptional regulator
C9E41_RS22725	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
C9E41_RS22735	COG1609	Transcriptional regulator
C9E41_RS22740	COG3250	beta-galactosidase activity
C9E41_RS22745	COG2223	nitrite transmembrane transporter activity
C9E41_RS22750	COG0110	maltose O-acetyltransferase activity
C9E41_RS22755	COG2807	transmembrane transport
C9E41_RS22765	COG0288	reversible hydration of carbon dioxide
C9E41_RS22770	COG0583	DNA-binding transcription factor activity
C9E41_RS22775	COG0402	S-adenosylhomocysteine deaminase activity
C9E41_RS22780	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C9E41_RS22785	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C9E41_RS22790	COG2079	MmgE PrpD family protein
C9E41_RS22795	COG0372	Belongs to the citrate synthase family
C9E41_RS22800	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C9E41_RS22805	COG3829	transcription factor binding
C9E41_RS22815	COG1280	lysine exporter protein (LysE YggA)
C9E41_RS22830	COG1064	alcohol dehydrogenase
C9E41_RS22840	COG1172	Belongs to the binding-protein-dependent transport system permease family
C9E41_RS22850	COG1879	ABC-type sugar transport system periplasmic component
C9E41_RS22860	COG0402	S-adenosylhomocysteine deaminase activity
C9E41_RS22865	COG0549	Belongs to the carbamate kinase family
C9E41_RS22875	COG1304	FMN binding
C9E41_RS22880	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C9E41_RS22890	COG0666	response to abiotic stimulus
C9E41_RS22905	COG2771	luxR family
C9E41_RS22905	COG2200	EAL domain
C9E41_RS22915	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C9E41_RS22945	COG2771	luxR family
C9E41_RS22945	COG2200	EAL domain
C9E41_RS22975	COG1556	Lactate utilization protein
C9E41_RS22980	COG1139	Iron-sulfur cluster binding protein
C9E41_RS22985	COG0247	lactate metabolic process
C9E41_RS22990	COG2207	Transcriptional regulator
C9E41_RS22995	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C9E41_RS23005	COG3059	membrane
C9E41_RS23010	COG0656	L-ascorbic acid biosynthetic process
C9E41_RS23015	COG3708	Transcriptional regulator
C9E41_RS23015	COG2207	Transcriptional regulator
C9E41_RS23020	COG1388	LysM domain
C9E41_RS23035	COG0583	DNA-binding transcription factor activity
C9E41_RS23040	COG1073	alpha beta
C9E41_RS23045	COG1902	pentaerythritol trinitrate reductase activity
C9E41_RS23055	COG4372	Transposase
C9E41_RS23060	COG3436	PFAM IS66 Orf2 family protein
C9E41_RS23105	COG3188	usher protein
C9E41_RS23115	COG3121	Chaperone
C9E41_RS23120	COG0727	PFAM Uncharacterised protein family (UPF0153)
C9E41_RS23125	COG3477	response to acidic pH
C9E41_RS23130	COG2080	2 iron, 2 sulfur cluster binding
C9E41_RS23135	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C9E41_RS23140	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C9E41_RS23145	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C9E41_RS23160	COG0583	DNA-binding transcription factor activity
C9E41_RS23175	COG4221	oxidoreductase activity
C9E41_RS23180	COG0583	DNA-binding transcription factor activity
C9E41_RS23265	COG0582	viral genome integration into host DNA
C9E41_RS23285	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C9E41_RS23300	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C9E41_RS23365	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C9E41_RS23385	COG2195	Cleaves the N-terminal amino acid of tripeptides
C9E41_RS23390	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
C9E41_RS23395	COG1690	Belongs to the RtcB family
C9E41_RS23400	COG0454	-acetyltransferase
C9E41_RS23410	COG2161	toxin-antitoxin pair type II binding
C9E41_RS23415	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C9E41_RS23435	COG0791	NLP P60 protein
C9E41_RS23440	COG3077	Addiction module antitoxin, RelB DinJ family
C9E41_RS23445	COG3041	Addiction module toxin RelE StbE family
C9E41_RS23450	COG3034	peptidoglycan biosynthetic process
C9E41_RS23455	COG0121	glutamine amidotransferase
C9E41_RS23465	COG1960	acyl-CoA dehydrogenase activity
C9E41_RS23475	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C9E41_RS23480	COG5433	transposase activity
C9E41_RS23495	COG3209	COG3209 Rhs family protein
C9E41_RS23500	COG5433	transposase activity
C9E41_RS23515	COG3209	COG3209 Rhs family protein
C9E41_RS23640	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C9E41_RS23650	COG2226	methyltransferase
C9E41_RS23660	COG1388	LysM domain
C9E41_RS23660	COG0741	lytic transglycosylase activity
C9E41_RS23665	COG2226	methyltransferase
C9E41_RS23675	COG0583	DNA-binding transcription factor activity
C9E41_RS23680	COG0656	L-ascorbic acid biosynthetic process
C9E41_RS23715	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C9E41_RS23720	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C9E41_RS23725	COG2011	ABC-type metal ion transport system permease component
C9E41_RS23730	COG1464	Belongs to the NlpA lipoprotein family
C9E41_RS23740	COG1720	tRNA m6t6A37 methyltransferase activity
C9E41_RS23750	COG0791	NLP P60 protein
C9E41_RS23755	COG3015	lipoprotein NlpE involved in copper resistance
C9E41_RS23760	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
C9E41_RS23775	COG4568	rho-dependent transcription termination
C9E41_RS23780	COG0037	tRNA processing
C9E41_RS23785	COG0346	lactoylglutathione lyase activity
C9E41_RS23790	COG1982	Orn Lys Arg decarboxylase major
C9E41_RS23800	COG0587	DNA-directed DNA polymerase activity
C9E41_RS23825	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C9E41_RS23830	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
C9E41_RS23840	COG0750	zinc metalloprotease
C9E41_RS23845	COG0575	Belongs to the CDS family
C9E41_RS23850	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C9E41_RS23855	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C9E41_RS23880	COG0024	Methionine aminopeptidase
C9E41_RS23900	COG3835	regulator
C9E41_RS23905	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C9E41_RS23920	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C9E41_RS23925	COG2860	membrane
C9E41_RS23950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C9E41_RS23955	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C9E41_RS23960	COG1120	ATPase activity
C9E41_RS23965	COG4774	siderophore transport
C9E41_RS23970	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C9E41_RS23975	COG1643	Atp-dependent helicase
C9E41_RS23980	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C9E41_RS23990	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C9E41_RS23995	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C9E41_RS24000	COG0617	tRNA 3'-terminal CCA addition
C9E41_RS24005	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C9E41_RS24015	COG3121	Chaperone
C9E41_RS24020	COG3188	usher protein
C9E41_RS24025	COG3539	Fimbrial protein
C9E41_RS24030	COG3539	Fimbrial protein
C9E41_RS24055	COG5464	transposase or invertase
C9E41_RS24065	COG0726	polysaccharide deacetylase
C9E41_RS24070	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9E41_RS24075	COG0842	Transport permease protein
C9E41_RS24080	COG1131	(ABC) transporter
C9E41_RS24085	COG0288	reversible hydration of carbon dioxide
C9E41_RS24090	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
C9E41_RS24095	COG4993	Dehydrogenase
C9E41_RS24100	COG2132	Multicopper oxidase
C9E41_RS24125	COG1049	propionate catabolic process, 2-methylcitrate cycle
C9E41_RS24130	COG3064	Membrane
C9E41_RS24135	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C9E41_RS24140	COG0508	dehydrogenase complex catalyzes the overall conversion of
C9E41_RS24145	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
C9E41_RS24150	COG2186	Transcriptional regulator
C9E41_RS24155	COG1113	amino acid transport
C9E41_RS24160	COG3725	Membrane protein required for beta-lactamase induction
C9E41_RS24165	COG3023	N-Acetylmuramoyl-L-alanine amidase
C9E41_RS24170	COG0157	Belongs to the NadC ModD family
C9E41_RS24175	COG4969	Belongs to the N-Me-Phe pilin family
C9E41_RS24180	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C9E41_RS24185	COG1459	type II secretion system
C9E41_RS24195	COG0237	dephospho-CoA kinase activity
C9E41_RS24210	COG0494	nUDIX hydrolase
C9E41_RS24230	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C9E41_RS24235	COG0849	cell division
C9E41_RS24240	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C9E41_RS24245	COG1181	Belongs to the D-alanine--D-alanine ligase family
C9E41_RS24260	COG0772	Belongs to the SEDS family
C9E41_RS24265	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C9E41_RS24275	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C9E41_RS24280	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C9E41_RS24285	COG0768	penicillin binding
C9E41_RS24290	COG3116	cell division
C9E41_RS24305	COG1609	Transcriptional regulator
C9E41_RS24315	COG0440	acetolactate synthase activity
C9E41_RS24320	COG0028	Belongs to the TPP enzyme family
C9E41_RS24325	COG0583	DNA-binding transcription factor activity
C9E41_RS24340	COG0473	3-isopropylmalate dehydrogenase activity
C9E41_RS24360	COG4533	DNA binding
C9E41_RS24370	COG4143	(ABC) transporter
C9E41_RS24375	COG1178	ABC-type Fe3 transport system permease component
C9E41_RS24380	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
C9E41_RS24385	COG0586	Pfam SNARE associated Golgi protein
C9E41_RS24390	COG4977	sequence-specific DNA binding
C9E41_RS24405	COG0235	Class ii aldolase
C9E41_RS24410	COG0417	DNA replication proofreading
C9E41_RS24420	COG0564	pseudouridine synthase activity
C9E41_RS24430	COG1357	PFAM Pentapeptide repeats (8 copies)
C9E41_RS24435	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
C9E41_RS24440	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
C9E41_RS24445	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C9E41_RS24480	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C9E41_RS24495	COG2271	Major facilitator Superfamily
C9E41_RS24500	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C9E41_RS24505	COG0644	oxidoreductase
C9E41_RS24540	COG1024	Enoyl-CoA hydratase
C9E41_RS24555	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C9E41_RS24560	COG0505	Belongs to the CarA family
C9E41_RS24580	COG1047	Peptidyl-prolyl cis-trans
C9E41_RS24595	COG0196	riboflavin kinase activity
C9E41_RS24620	COG3121	Chaperone
C9E41_RS24625	COG3188	usher protein
C9E41_RS24635	COG0583	DNA-binding transcription factor activity
C9E41_RS24665	COG4735	regulation of single-species biofilm formation
C9E41_RS24670	COG1584	GPR1 FUN34 yaaH family protein
C9E41_RS24675	COG0521	Mo-molybdopterin cofactor biosynthetic process
C9E41_RS24680	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C9E41_RS24685	COG1115	amino acid carrier protein
C9E41_RS24700	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C9E41_RS24710	COG0460	homoserine dehydrogenase
C9E41_RS24710	COG0527	aspartate kinase activity
C9E41_RS24720	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
C9E41_RS24730	COG0745	RESPONSE REGULATOR receiver
C9E41_RS24735	COG4452	Inner membrane protein CreD
C9E41_RS24740	COG2205	protein histidine kinase activity
C9E41_RS24745	COG0745	RESPONSE REGULATOR receiver
C9E41_RS24750	COG3045	CreA protein
C9E41_RS24755	COG2207	Transcriptional regulator
C9E41_RS24755	COG3708	Transcriptional regulator
C9E41_RS24765	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
C9E41_RS24775	COG0741	lytic transglycosylase activity
C9E41_RS24780	COG0488	(ABC) transporter
C9E41_RS24785	COG3172	ATPase kinase involved in NAD metabolism
C9E41_RS24785	COG1056	cytidyltransferase-related domain
C9E41_RS24790	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C9E41_RS24795	COG0560	Phosphoserine phosphatase
C9E41_RS24805	COG3726	membrane protein affecting hemolysin expression
C9E41_RS24805	COG0095	Lipoate-protein ligase
C9E41_RS24840	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C9E41_RS24845	COG0084	hydrolase, TatD family'
C9E41_RS24850	COG4667	esterase of the alpha-beta hydrolase superfamily
C9E41_RS24860	COG2823	Periplasmic or secreted lipoprotein
C9E41_RS24870	COG1011	Hydrolase
C9E41_RS24875	COG0456	acetyltransferase
C9E41_RS24880	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
C9E41_RS24900	COG4114	ferric iron reductase
C9E41_RS24905	COG2197	response regulator
C9E41_RS24910	COG2197	response regulator
C9E41_RS24915	COG2966	Psort location CytoplasmicMembrane, score
C9E41_RS24930	COG1484	DNA-dependent DNA replication
C9E41_RS24945	COG1063	alcohol dehydrogenase
C9E41_RS24950	COG1802	Transcriptional regulator
C9E41_RS24955	COG2271	Major facilitator Superfamily
C9E41_RS24960	COG0840	transmembrane signaling receptor activity
C9E41_RS24970	COG1966	Carbon starvation protein
C9E41_RS24975	COG2879	small protein
C9E41_RS24980	COG0523	cobalamin synthesis protein
C9E41_RS25005	COG0732	type I restriction modification DNA specificity domain
C9E41_RS25025	COG5457	Domain of unknown function (DUF1127)
C9E41_RS25030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C9E41_RS25040	COG2814	Major facilitator Superfamily
C9E41_RS25045	COG2733	membrane
C9E41_RS25050	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
C9E41_RS25055	COG1924	4 iron, 4 sulfur cluster binding
C9E41_RS25075	COG3204	pilus organization
C9E41_RS25080	COG0477	Major facilitator Superfamily
C9E41_RS25095	COG3366	ferrous iron transmembrane transporter activity
C9E41_RS25100	COG0700	Nucleoside recognition
C9E41_RS25105	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C9E41_RS25130	COG2186	Transcriptional regulator
C9E41_RS25135	COG0246	Mannitol dehydrogenase
C9E41_RS25145	COG2610	gluconate transmembrane transporter activity
C9E41_RS25150	COG3539	Fimbrial protein
C9E41_RS25155	COG3539	Fimbrial protein
C9E41_RS25160	COG3539	Fimbrial protein
C9E41_RS25165	COG3188	usher protein
C9E41_RS25170	COG3121	Chaperone
C9E41_RS25175	COG3539	Fimbrial protein
C9E41_RS25180	COG3539	Fimbrial protein
C9E41_RS25185	COG4974	Belongs to the 'phage' integrase family
C9E41_RS25190	COG0582	viral genome integration into host DNA
C9E41_RS25195	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
C9E41_RS25200	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
C9E41_RS25215	COG0210	DNA helicase
C9E41_RS25220	COG1111	helicase
C9E41_RS25220	COG1205	dead DEAH box helicase
C9E41_RS25230	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C9E41_RS25275	COG0582	viral genome integration into host DNA
C9E41_RS25335	COG1064	alcohol dehydrogenase
C9E41_RS25340	COG0433	COG0433 Predicted ATPase
C9E41_RS25345	COG0795	lipopolysaccharide-transporting ATPase activity
C9E41_RS25350	COG0795	lipopolysaccharide-transporting ATPase activity
C9E41_RS25360	COG2927	DNA polymerase III (CHI subunit)
C9E41_RS25370	COG4269	membrane
C9E41_RS25375	COG0456	acetyltransferase
C9E41_RS25380	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
C9E41_RS25385	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C9E41_RS25395	COG2731	YhcH YjgK YiaL family protein
C9E41_RS25400	COG1309	transcriptional regulator
C9E41_RS25405	COG1028	Short-chain dehydrogenase reductase Sdr
C9E41_RS25410	COG0251	oxidation-reduction process
C9E41_RS25430	COG0251	oxidation-reduction process
C9E41_RS25435	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C9E41_RS25445	COG1609	Transcriptional regulator
C9E41_RS25450	COG1263	PTS System
C9E41_RS25450	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C9E41_RS25455	COG0366	Alpha amylase catalytic
C9E41_RS25460	COG1328	CTP reductase activity
C9E41_RS25465	COG0602	queuosine metabolic process
C9E41_RS25470	COG3783	Cytochrome b(562)
C9E41_RS25475	COG0312	modulator of DNA gyrase
C9E41_RS25485	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C9E41_RS25495	COG1172	Belongs to the binding-protein-dependent transport system permease family
C9E41_RS25500	COG1172	Belongs to the binding-protein-dependent transport system permease family
C9E41_RS25505	COG1129	ABC transporter
C9E41_RS25510	COG1879	ABC-type sugar transport system periplasmic component
C9E41_RS25515	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
C9E41_RS25520	COG2337	Toxic component of a toxin-antitoxin (TA) module
C9E41_RS25525	COG2336	PFAM SpoVT AbrB
C9E41_RS25530	COG2105	PFAM AIG2 family protein
C9E41_RS25535	COG2911	Protein conserved in bacteria
C9E41_RS25540	COG0729	surface antigen
C9E41_RS25550	COG1253	flavin adenine dinucleotide binding
C9E41_RS25560	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
C9E41_RS25570	COG1218	3'(2'),5'-bisphosphate nucleotidase
C9E41_RS25575	COG0737	Belongs to the 5'-nucleotidase family
C9E41_RS25580	COG1733	regulation of RNA biosynthetic process
C9E41_RS25585	COG0702	epimerase
C9E41_RS25590	COG0697	spore germination
C9E41_RS25600	COG1113	amino acid transport
C9E41_RS25605	COG0545	Peptidyl-prolyl cis-trans isomerase
C9E41_RS25610	COG3061	Opacity-associated protein A
C9E41_RS25620	COG0675	Transposase, IS605 OrfB family
C9E41_RS25645	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C9E41_RS25680	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9E41_RS25685	COG3414	Phosphotransferase system galactitol-specific IIB component
C9E41_RS25690	COG3037	sugar-specific permease SgaT UlaA
C9E41_RS25705	COG1073	alpha beta
C9E41_RS25710	COG3650	response to hydrogen peroxide
C9E41_RS25720	COG1960	acyl-CoA dehydrogenase activity
C9E41_RS25725	COG0754	glutathionylspermidine amidase activity
C9E41_RS25730	COG5463	Belongs to the UPF0441 family
C9E41_RS25735	COG3766	membrane
C9E41_RS25745	COG1842	Phage shock protein A
C9E41_RS25750	COG3789	protein conserved in bacteria
C9E41_RS25755	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C9E41_RS25760	COG0557	exoribonuclease II activity
C9E41_RS25775	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
C9E41_RS25780	COG0330	HflC and HflK could
C9E41_RS25785	COG0330	HflC and HflK could
C9E41_RS25790	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C9E41_RS25805	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C9E41_RS25810	COG0860	N-Acetylmuramoyl-L-alanine amidase
C9E41_RS25815	COG0802	atpase or kinase
C9E41_RS25820	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C9E41_RS25820	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C9E41_RS25850	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
C9E41_RS25865	COG3264	Mechanosensitive ion channel
C9E41_RS25865	COG1511	domain protein
C9E41_RS25870	COG0531	amino acid
C9E41_RS25880	COG1053	succinate dehydrogenase
C9E41_RS25885	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C9E41_RS25900	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C9E41_RS25905	COG3040	lipid binding
C9E41_RS25910	COG2076	Multidrug Resistance protein
C9E41_RS25915	COG5510	response to toxic substance
C9E41_RS25920	COG5510	response to toxic substance
C9E41_RS25930	COG1509	lysine 2,3-aminomutase activity
C9E41_RS25955	COG0531	amino acid
C9E41_RS25960	COG3030	protein affecting phage T7 exclusion by the F plasmid
C9E41_RS25965	COG1027	Aspartate ammonia-lyase
C9E41_RS25970	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C9E41_RS25980	COG4232	protein-disulfide reductase activity
C9E41_RS25985	COG1309	transcriptional regulator
C9E41_RS25995	COG3710	Transcriptional regulator
C9E41_RS26005	COG0531	amino acid
C9E41_RS26010	COG1982	Orn Lys Arg decarboxylase major
C9E41_RS26015	COG3104	oligopeptide transport
C9E41_RS26020	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C9E41_RS26035	COG2388	GCN5-related N-acetyl-transferase
C9E41_RS26040	COG3592	Divergent 4Fe-4S mono-cluster
C9E41_RS26045	COG3290	protein histidine kinase activity
C9E41_RS26050	COG4565	transcriptional regulatory protein
C9E41_RS26060	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C9E41_RS26065	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C9E41_RS26065	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C9E41_RS26070	COG3647	Membrane
C9E41_RS26080	COG2211	Major facilitator Superfamily
C9E41_RS26085	COG1486	melibiose metabolic process
C9E41_RS26090	COG2169	Transcriptional regulator
C9E41_RS26095	COG1982	Orn Lys Arg decarboxylase major
C9E41_RS26100	COG2207	Transcriptional regulator
C9E41_RS26105	COG0531	amino acid
C9E41_RS26110	COG2194	sulfuric ester hydrolase activity
C9E41_RS26115	COG0745	RESPONSE REGULATOR receiver
C9E41_RS26120	COG0642	Histidine kinase
C9E41_RS26130	COG0477	Major facilitator Superfamily
C9E41_RS26140	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C9E41_RS26145	COG2824	Alkylphosphonate utilization operon protein PhnA
C9E41_RS26150	COG2764	glyoxalase bleomycin resistance protein dioxygenase
C9E41_RS26155	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
C9E41_RS26160	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
C9E41_RS26165	COG3639	organic phosphonate transmembrane transporter activity
C9E41_RS26170	COG2188	Transcriptional regulator
C9E41_RS26175	COG3624	Phosphonate C-P lyase system protein PhnG
C9E41_RS26180	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
C9E41_RS26185	COG3626	phosphonate metabolism
C9E41_RS26190	COG3627	carbon phosphorus lyase activity
C9E41_RS26195	COG4107	phosphonate C-P lyase system protein PhnK
C9E41_RS26200	COG4778	phosphonate C-P lyase system protein PhnL
C9E41_RS26205	COG3454	Phosphonate metabolism
C9E41_RS26210	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
C9E41_RS26215	COG0456	acetyltransferase
C9E41_RS26220	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C9E41_RS26240	COG1129	ABC transporter
C9E41_RS26245	COG1172	Belongs to the binding-protein-dependent transport system permease family
C9E41_RS26265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C9E41_RS26275	COG2015	COG2015, Alkyl sulfatase and related hydrolases
C9E41_RS26285	COG1566	PFAM secretion protein HlyD family protein
C9E41_RS26290	COG1289	transmembrane transporter activity
C9E41_RS26295	COG1538	Outer membrane efflux protein
C9E41_RS26305	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C9E41_RS26310	COG1301	dicarboxylic acid transport
C9E41_RS26315	COG4235	cytochrome complex assembly
C9E41_RS26320	COG3088	subunit of a heme lyase
C9E41_RS26325	COG1138	Cytochrome C-type biogenesis protein
C9E41_RS26330	COG3301	Polysulphide reductase, NrfD
C9E41_RS26335	COG0437	4 iron, 4 sulfur cluster binding
C9E41_RS26340	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
C9E41_RS26350	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C9E41_RS26355	COG3162	membrane
C9E41_RS26365	COG1357	PFAM Pentapeptide repeats (8 copies)
C9E41_RS26370	COG0025	NhaP-type Na H and K H
C9E41_RS26375	COG2252	PERMEase
C9E41_RS26380	COG0789	Transcriptional regulator
C9E41_RS26385	COG2207	Transcriptional regulator
C9E41_RS26390	COG4943	cyclic-guanylate-specific phosphodiesterase activity
C9E41_RS26400	COG0629	single-stranded DNA binding
C9E41_RS26405	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C9E41_RS26410	COG2315	Protein conserved in bacteria
C9E41_RS26415	COG0432	Pfam Uncharacterised protein family UPF0047
C9E41_RS26420	COG3700	Belongs to the class B bacterial acid phosphatase family
C9E41_RS26430	COG1448	Aminotransferase
C9E41_RS26435	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C9E41_RS26440	COG0305	Participates in initiation and elongation during chromosome replication
C9E41_RS26445	COG0604	alcohol dehydrogenase
C9E41_RS26455	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C9E41_RS26465	COG0735	belongs to the Fur family
C9E41_RS26470	COG3237	CsbD-like
C9E41_RS26475	COG0534	Mate efflux family protein
C9E41_RS26485	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C9E41_RS26505	COG1357	PFAM Pentapeptide repeats (8 copies)
C9E41_RS26520	COG3842	ATPase activity
C9E41_RS26530	COG2182	Extracellular solute-binding protein
C9E41_RS26535	COG1175	transmembrane transport
C9E41_RS26540	COG3833	ABC-type maltose transport systems, permease component
C9E41_RS26545	COG0477	Major facilitator Superfamily
C9E41_RS26545	COG2814	Major facilitator Superfamily
C9E41_RS26560	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C9E41_RS26585	COG0527	aspartate kinase activity
C9E41_RS26595	COG1187	pseudouridine synthase activity
C9E41_RS26640	COG1283	sodium-dependent phosphate transmembrane transporter activity
C9E41_RS26645	COG1410	methionine synthase
C9E41_RS26645	COG0646	methionine synthase
C9E41_RS26650	COG1414	Transcriptional regulator
C9E41_RS26665	COG2224	Isocitrate lyase
C9E41_RS26670	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C9E41_RS26680	COG0456	acetyltransferase
C9E41_RS26710	COG0151	Belongs to the GarS family
C9E41_RS26715	COG2204	response regulator
C9E41_RS26720	COG4191	Histidine kinase
C9E41_RS26725	COG3678	ATP-independent chaperone mediated protein folding
C9E41_RS26740	COG3068	Protein conserved in bacteria
C9E41_RS26775	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C9E41_RS26780	COG2104	thiamine diphosphate biosynthetic process
C9E41_RS26785	COG2022	thiamine diphosphate biosynthetic process
C9E41_RS26790	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
C9E41_RS26830	COG0250	Participates in transcription elongation, termination and antitermination
C9E41_RS26835	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C9E41_RS26870	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
C9E41_RS26870	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
C9E41_RS26875	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C9E41_RS26900	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C9E41_RS26905	COG4206	TonB-dependent receptor
C9E41_RS26910	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C9E41_RS26920	COG1309	transcriptional regulator
C9E41_RS26925	COG0477	Major facilitator Superfamily
C9E41_RS26930	COG1473	amidohydrolase
C9E41_RS26935	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C9E41_RS26940	COG0583	DNA-binding transcription factor activity
C9E41_RS26945	COG0165	Argininosuccinate lyase
C9E41_RS26955	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C9E41_RS26970	COG2194	sulfuric ester hydrolase activity
C9E41_RS26975	COG2207	Transcriptional regulator
C9E41_RS26980	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C9E41_RS26985	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C9E41_RS26990	COG1882	Formate acetyltransferase
C9E41_RS26995	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C9E41_RS27005	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C9E41_RS27005	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9E41_RS27005	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9E41_RS27010	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C9E41_RS27015	COG0371	Dehydrogenase
C9E41_RS27020	COG3738	Protein conserved in bacteria
C9E41_RS27025	COG0697	spore germination
C9E41_RS27035	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C9E41_RS27040	COG0527	aspartate kinase activity
C9E41_RS27040	COG0460	homoserine dehydrogenase
C9E41_RS27045	COG0626	cystathionine gamma-synthase activity
C9E41_RS27055	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
C9E41_RS27070	COG3209	COG3209 Rhs family protein
C9E41_RS27080	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C9E41_RS27085	COG1609	Transcriptional regulator
C9E41_RS27090	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C9E41_RS27105	COG1575	Belongs to the MenA family. Type 1 subfamily
C9E41_RS27130	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C9E41_RS27140	COG1494	fructose-1,6-bisphosphatase
C9E41_RS27150	COG0589	response to stress
C9E41_RS27155	COG3691	Protein conserved in bacteria
C9E41_RS27160	COG3152	Membrane
C9E41_RS27180	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C9E41_RS27195	COG3678	ATP-independent chaperone mediated protein folding
C9E41_RS27200	COG0745	RESPONSE REGULATOR receiver
C9E41_RS27205	COG2205	protein histidine kinase activity
C9E41_RS27210	COG2258	MOSC domain
C9E41_RS27220	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C9E41_RS27230	COG1917	Cupin 2, conserved barrel domain protein
C9E41_RS27230	COG4977	sequence-specific DNA binding
C9E41_RS27265	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9E41_RS27270	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C9E41_RS27270	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C9E41_RS27275	COG1363	Peptidase, m42
C9E41_RS27280	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9E41_RS27280	COG3711	transcriptional antiterminator
C9E41_RS27300	COG0437	4 iron, 4 sulfur cluster binding
C9E41_RS27305	COG2864	formate dehydrogenase
C9E41_RS27315	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C9E41_RS27320	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C9E41_RS27345	COG0456	acetyltransferase
C9E41_RS27360	COG1011	Hydrolase
C9E41_RS27365	COG1349	DNA-binding transcription factor activity
C9E41_RS27370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C9E41_RS27375	COG2084	Dehydrogenase
C9E41_RS27380	COG3684	Belongs to the aldolase LacD family
C9E41_RS27385	COG2942	2-epimerase
C9E41_RS27390	COG2017	converts alpha-aldose to the beta-anomer
C9E41_RS27400	COG1501	Belongs to the glycosyl hydrolase 31 family
C9E41_RS27405	COG2211	Major facilitator Superfamily
C9E41_RS27410	COG2211	Major facilitator Superfamily
C9E41_RS27415	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
C9E41_RS27420	COG2271	Major facilitator Superfamily
C9E41_RS27425	COG1082	Xylose isomerase domain protein TIM barrel
C9E41_RS27430	COG2188	Transcriptional regulator
C9E41_RS27435	COG1217	gtp-binding protein TYPA
C9E41_RS27440	COG0174	glutamine synthetase
C9E41_RS27445	COG3852	Histidine kinase
C9E41_RS27450	COG2204	response regulator
C9E41_RS27460	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C9E41_RS27465	COG3078	GTPase activator activity
C9E41_RS27475	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C9E41_RS27475	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C9E41_RS27485	COG0204	Acyl-transferase
C9E41_RS27490	COG5339	Protein conserved in bacteria
C9E41_RS27495	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C9E41_RS27500	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C9E41_RS27505	COG3084	Protein conserved in bacteria
C9E41_RS27510	COG0746	molybdenum cofactor guanylyltransferase activity
C9E41_RS27515	COG1763	Mo-molybdopterin cofactor biosynthetic process
C9E41_RS27545	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
C9E41_RS27550	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C9E41_RS27555	COG1739	Uncharacterized protein family UPF0029
C9E41_RS27570	COG0183	Belongs to the thiolase family
C9E41_RS27575	COG0543	2 iron, 2 sulfur cluster binding
C9E41_RS27580	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C9E41_RS27585	COG0250	Participates in transcription elongation, termination and antitermination
C9E41_RS27590	COG0084	hydrolase, TatD family'
C9E41_RS27595	COG0805	protein transport
C9E41_RS27600	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C9E41_RS27605	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C9E41_RS27615	COG3165	ubiquinone biosynthetic process from chorismate
C9E41_RS27625	COG1322	Protein conserved in bacteria
C9E41_RS27630	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
C9E41_RS27635	COG0412	Dienelactone hydrolase
C9E41_RS27640	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C9E41_RS27645	COG0583	DNA-binding transcription factor activity
C9E41_RS27650	COG0697	spore germination
C9E41_RS27655	COG0561	phosphatase activity
C9E41_RS27660	COG2267	carboxylic ester hydrolase activity
C9E41_RS27665	COG1280	lysine exporter protein (LysE YggA)
C9E41_RS27670	COG1280	lysine exporter protein (LysE YggA)
C9E41_RS27675	COG0514	ATP-dependent DNA helicase (RecQ)
C9E41_RS27680	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
C9E41_RS27685	COG2050	protein possibly involved in aromatic compounds catabolism
C9E41_RS27690	COG2962	Rard protein
C9E41_RS27720	COG0598	Magnesium transport protein CorA
C9E41_RS27725	COG3698	Phosphodiester glycosidase
C9E41_RS27730	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
C9E41_RS27735	COG0210	DNA helicase
C9E41_RS27740	COG1011	Hydrolase
C9E41_RS27750	COG3159	Protein conserved in bacteria
C9E41_RS27760	COG5567	small periplasmic lipoprotein
C9E41_RS27775	COG3072	Adenylate cyclase
C9E41_RS27785	COG1587	Uroporphyrinogen-III synthase
C9E41_RS27790	COG2959	enzyme of heme biosynthesis
C9E41_RS27795	COG3071	HemY protein
C9E41_RS27800	COG3119	arylsulfatase activity
C9E41_RS27805	COG0641	radical SAM
C9E41_RS27840	COG1113	amino acid transport
C9E41_RS27855	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C9E41_RS27860	COG2244	polysaccharide biosynthetic process
C9E41_RS27865	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C9E41_RS27870	COG0456	acetyltransferase
C9E41_RS27875	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C9E41_RS27880	COG1088	dTDP-glucose 4,6-dehydratase activity
C9E41_RS27885	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
C9E41_RS27890	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C9E41_RS27895	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
C9E41_RS27900	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C9E41_RS27905	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C9E41_RS27915	COG3118	belongs to the thioredoxin family
C9E41_RS27920	COG0513	Belongs to the DEAD box helicase family
C9E41_RS27930	COG0210	DNA helicase
C9E41_RS27935	COG3692	DNA binding
C9E41_RS27940	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C9E41_RS27950	COG0583	DNA-binding transcription factor activity
C9E41_RS27955	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C9E41_RS27965	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C9E41_RS27970	COG3978	acetolactate synthase activity
C9E41_RS27990	COG0606	chelatase, subunit chli
C9E41_RS27995	COG3085	chromosome segregation
C9E41_RS28035	COG2186	Transcriptional regulator
C9E41_RS28040	COG0477	Major facilitator Superfamily
C9E41_RS28045	COG1609	Transcriptional regulator
C9E41_RS28050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C9E41_RS28055	COG1879	ABC-type sugar transport system periplasmic component
C9E41_RS28060	COG1172	Belongs to the binding-protein-dependent transport system permease family
C9E41_RS28065	COG1129	ABC transporter
C9E41_RS28075	COG3158	transport of potassium into the cell
C9E41_RS28095	COG1522	sequence-specific DNA binding
C9E41_RS28100	COG0716	FMN binding
C9E41_RS28180	COG3468	outer membrane autotransporter barrel domain protein
C9E41_RS28195	COG0726	polysaccharide deacetylase
C9E41_RS28200	COG0297	glycogen (starch) synthase activity
C9E41_RS28205	COG2194	sulfuric ester hydrolase activity
C9E41_RS28210	COG1560	Kdo2-lipid A biosynthetic process
C9E41_RS28245	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C9E41_RS28320	COG2274	protein secretion by the type I secretion system
C9E41_RS28545	COG1475	DNA binding
C9E41_RS28635	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
C9E41_RS28645	COG1525	nuclease