locus-tag	class	description
C9E46_RS00015	COG3312	ion transport
C9E46_RS00065	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C9E46_RS00090	COG3539	Fimbrial protein
C9E46_RS00100	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C9E46_RS00105	COG0573	inorganic phosphate transmembrane transporter activity
C9E46_RS00110	COG0581	inorganic phosphate transmembrane transporter activity
C9E46_RS00115	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C9E46_RS00120	COG0704	Plays a role in the regulation of phosphate uptake
C9E46_RS00160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C9E46_RS00165	COG2252	PERMEase
C9E46_RS00170	COG0431	NADPH-dependent FMN reductase
C9E46_RS00175	COG2091	lysine biosynthetic process via aminoadipic acid
C9E46_RS00190	COG0814	amino acid
C9E46_RS00245	COG0592	DNA-directed DNA polymerase activity
C9E46_RS00255	COG0187	DNA topoisomerase II activity
C9E46_RS00260	COG3753	Protein conserved in bacteria
C9E46_RS00265	COG0561	phosphatase activity
C9E46_RS00275	COG0644	oxidoreductase
C9E46_RS00280	COG0823	Involved in the tonB-independent uptake of proteins
C9E46_RS00285	COG5645	(Lipo)protein
C9E46_RS00305	COG2188	Transcriptional regulator
C9E46_RS00320	COG2207	Transcriptional regulator
C9E46_RS00325	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C9E46_RS00330	COG3119	arylsulfatase activity
C9E46_RS00340	COG2149	membrane
C9E46_RS00350	COG0641	radical SAM
C9E46_RS00355	COG2814	Major facilitator Superfamily
C9E46_RS00370	COG0028	Belongs to the TPP enzyme family
C9E46_RS00375	COG0440	acetolactate synthase activity
C9E46_RS00400	COG2197	response regulator
C9E46_RS00405	COG3851	Histidine kinase
C9E46_RS00410	COG2271	Major facilitator Superfamily
C9E46_RS00415	COG2271	Major facilitator Superfamily
C9E46_RS00450	COG2814	Major facilitator Superfamily
C9E46_RS00460	COG1464	Belongs to the NlpA lipoprotein family
C9E46_RS00465	COG0697	spore germination
C9E46_RS00635	COG5492	domain, Protein
C9E46_RS00695	COG4372	Transposase
C9E46_RS00700	COG3436	PFAM IS66 Orf2 family protein
C9E46_RS00740	COG0582	viral genome integration into host DNA
C9E46_RS00750	COG2211	Major facilitator Superfamily
C9E46_RS00755	COG1501	Belongs to the glycosyl hydrolase 31 family
C9E46_RS00760	COG2982	Protein involved in outer membrane biogenesis
C9E46_RS00765	COG2233	PERMEase
C9E46_RS00770	COG0786	glutamate:sodium symporter activity
C9E46_RS00780	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C9E46_RS00785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C9E46_RS00790	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C9E46_RS00800	COG0194	GDP metabolic process
C9E46_RS00810	COG2860	membrane
C9E46_RS00815	COG3645	SOS response
C9E46_RS00820	COG1561	YicC-like family, N-terminal region
C9E46_RS00845	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C9E46_RS00875	COG1519	Transferase
C9E46_RS00880	COG0859	PFAM glycosyl transferase family 9
C9E46_RS00885	COG0438	transferase activity, transferring glycosyl groups
C9E46_RS00890	COG0515	serine threonine protein kinase
C9E46_RS00900	COG3642	lipopolysaccharide core region biosynthetic process
C9E46_RS00920	COG0859	PFAM glycosyl transferase family 9
C9E46_RS00925	COG0859	PFAM glycosyl transferase family 9
C9E46_RS00940	COG0156	8-amino-7-oxononanoate synthase activity
C9E46_RS00950	COG1216	Glycosyl transferase, family 2
C9E46_RS00955	COG2861	carbohydrate metabolic process
C9E46_RS00960	COG4942	peptidase
C9E46_RS00970	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C9E46_RS00975	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C9E46_RS00990	COG1045	serine acetyltransferase
C9E46_RS00995	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C9E46_RS01005	COG2186	Transcriptional regulator
C9E46_RS01010	COG1620	l-lactate permease
C9E46_RS01015	COG5295	Hep Hag repeat protein
C9E46_RS01040	COG3722	fumarate hydratase activity
C9E46_RS01050	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9E46_RS01050	COG2213	PTS system mannitol-specific
C9E46_RS01060	COG1566	PFAM secretion protein HlyD family protein
C9E46_RS01085	COG3209	COG3209 Rhs family protein
C9E46_RS01090	COG0625	glutathione transferase activity
C9E46_RS01100	COG3276	selenocysteine insertion sequence binding
C9E46_RS01105	COG1454	alcohol dehydrogenase
C9E46_RS01115	COG1012	belongs to the aldehyde dehydrogenase family
C9E46_RS01130	COG1566	PFAM secretion protein HlyD family protein
C9E46_RS01135	COG0583	DNA-binding transcription factor activity
C9E46_RS01140	COG3713	MltA-interacting MipA family protein
C9E46_RS01150	COG2211	Major facilitator Superfamily
C9E46_RS01160	COG1414	Transcriptional regulator
C9E46_RS01165	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C9E46_RS01170	COG3977	Valine--pyruvate aminotransferase
C9E46_RS01175	COG0366	Alpha amylase catalytic
C9E46_RS01180	COG2992	FlgJ-related protein
C9E46_RS01185	COG2207	Transcriptional regulator
C9E46_RS01185	COG1609	Transcriptional regulator
C9E46_RS01190	COG4214	carbohydrate transport
C9E46_RS01200	COG4213	ABC transporter substrate-binding protein
C9E46_RS01210	COG1070	Carbohydrate kinase
C9E46_RS01215	COG4682	membrane
C9E46_RS01220	COG4682	membrane
C9E46_RS01225	COG3274	enterobacterial common antigen metabolic process
C9E46_RS01250	COG1278	Cold shock
C9E46_RS01255	COG2944	sequence-specific DNA binding
C9E46_RS01270	COG2885	chlorophyll binding
C9E46_RS01275	COG0243	molybdopterin cofactor binding
C9E46_RS01280	COG0456	acetyltransferase
C9E46_RS01285	COG2818	Glycosylase
C9E46_RS01290	COG5571	outer membrane autotransporter
C9E46_RS01295	COG2223	nitrite transmembrane transporter activity
C9E46_RS01300	COG3539	Fimbrial protein
C9E46_RS01305	COG3121	Chaperone
C9E46_RS01315	COG3539	Fimbrial protein
C9E46_RS01325	COG2194	sulfuric ester hydrolase activity
C9E46_RS01335	COG0747	negative chemotaxis
C9E46_RS01345	COG0601	transmembrane transport
C9E46_RS01350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C9E46_RS01355	COG0444	Belongs to the ABC transporter superfamily
C9E46_RS01360	COG4608	Belongs to the ABC transporter superfamily
C9E46_RS01365	COG0814	amino acid
C9E46_RS01380	COG2194	sulfuric ester hydrolase activity
C9E46_RS01410	COG1215	transferase activity, transferring glycosyl groups
C9E46_RS01415	COG1215	transferase activity, transferring glycosyl groups
C9E46_RS01420	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
C9E46_RS01425	COG0457	Tetratricopeptide repeat
C9E46_RS01425	COG3118	belongs to the thioredoxin family
C9E46_RS01430	COG2200	EAL domain
C9E46_RS01430	COG2199	diguanylate cyclase activity
C9E46_RS01440	COG0612	Peptidase, M16
C9E46_RS01450	COG2200	EAL domain
C9E46_RS01455	COG2982	Protein involved in outer membrane biogenesis
C9E46_RS01460	COG0477	Major facilitator Superfamily
C9E46_RS01465	COG1295	ribonuclease BN
C9E46_RS01470	COG0583	DNA-binding transcription factor activity
C9E46_RS01475	COG2197	response regulator
C9E46_RS01485	COG1858	cytochrome C peroxidase
C9E46_RS01490	COG0076	glutamate decarboxylase activity
C9E46_RS01495	COG2207	Transcriptional regulator
C9E46_RS01500	COG2207	Transcriptional regulator
C9E46_RS01505	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C9E46_RS01510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C9E46_RS01520	COG2771	luxR family
C9E46_RS01525	COG3247	response to pH
C9E46_RS01540	COG1285	pathogenesis
C9E46_RS01545	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
C9E46_RS01550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C9E46_RS01560	COG3721	Heme iron utilization protein
C9E46_RS01570	COG4558	Periplasmic binding protein
C9E46_RS01580	COG4771	TonB-dependent receptor
C9E46_RS01585	COG3720	iron ion transport
C9E46_RS01590	COG2197	response regulator
C9E46_RS01595	COG3065	identical protein binding
C9E46_RS01605	COG1393	Belongs to the ArsC family
C9E46_RS01610	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C9E46_RS01615	COG0640	Transcriptional regulator
C9E46_RS01625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C9E46_RS01630	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
C9E46_RS01635	COG0339	signal peptide processing
C9E46_RS01645	COG3104	oligopeptide transport
C9E46_RS01655	COG0589	response to stress
C9E46_RS01665	COG0306	phosphate transporter
C9E46_RS01670	COG2081	HI0933 family
C9E46_RS01690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C9E46_RS01695	COG1129	ABC transporter
C9E46_RS01695	COG0842	Transport permease protein
C9E46_RS01700	COG0842	Transport permease protein
C9E46_RS01715	COG0191	fructose-bisphosphate aldolase activity
C9E46_RS01730	COG3775	system Galactitol-specific IIC component
C9E46_RS01735	COG3414	Phosphotransferase system galactitol-specific IIB component
C9E46_RS01745	COG2188	Transcriptional regulator
C9E46_RS01755	COG1124	(ABC) transporter
C9E46_RS01760	COG0444	Belongs to the ABC transporter superfamily
C9E46_RS01765	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C9E46_RS01770	COG0601	transmembrane transport
C9E46_RS01775	COG0747	negative chemotaxis
C9E46_RS01780	COG2091	lysine biosynthetic process via aminoadipic acid
C9E46_RS01785	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C9E46_RS01790	COG1028	Short-chain dehydrogenase reductase Sdr
C9E46_RS01800	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C9E46_RS01825	COG1216	Glycosyl transferase, family 2
C9E46_RS01845	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C9E46_RS01855	COG0204	Acyl-transferase
C9E46_RS01875	COG0628	permease
C9E46_RS01890	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C9E46_RS01905	COG3714	YhhN family
C9E46_RS01915	COG3776	membrane
C9E46_RS01920	COG0742	ribosomal rna small subunit methyltransferase
C9E46_RS01925	COG0552	protein localization to endoplasmic reticulum
C9E46_RS01930	COG2884	Cell division ATP-binding protein ftsE
C9E46_RS01935	COG2177	Part of the ABC transporter FtsEX involved in
C9E46_RS01940	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C9E46_RS01945	COG0683	leucine binding
C9E46_RS01960	COG0456	acetyltransferase
C9E46_RS01965	COG0683	leucine binding
C9E46_RS01970	COG0559	Belongs to the binding-protein-dependent transport system permease family
C9E46_RS01975	COG4177	L-phenylalanine transmembrane transporter activity
C9E46_RS01980	COG0411	ABC transporter
C9E46_RS01985	COG0410	ABC transporter
C9E46_RS01995	COG1653	transport
C9E46_RS02000	COG1175	transmembrane transport
C9E46_RS02010	COG3842	ATPase activity
C9E46_RS02015	COG0584	glycerophosphoryl diester phosphodiesterase
C9E46_RS02025	COG0405	Gamma-glutamyltransferase
C9E46_RS02040	COG1247	-acetyltransferase
C9E46_RS02045	COG0673	inositol 2-dehydrogenase activity
C9E46_RS02050	COG1741	Belongs to the pirin family
C9E46_RS02055	COG1609	Transcriptional regulator
C9E46_RS02060	COG3265	gluconokinase activity
C9E46_RS02065	COG2610	gluconate transmembrane transporter activity
C9E46_RS02070	COG0514	ATP-dependent DNA helicase (RecQ)
C9E46_RS02090	COG2095	MarC family integral membrane protein
C9E46_RS02095	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C9E46_RS02100	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
C9E46_RS02120	COG0058	SHG alpha-glucan phosphorylase activity
C9E46_RS02125	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C9E46_RS02140	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C9E46_RS02155	COG1349	DNA-binding transcription factor activity
C9E46_RS02160	COG4650	regulator
C9E46_RS02165	COG1690	Belongs to the RtcB family
C9E46_RS02190	COG0058	SHG alpha-glucan phosphorylase activity
C9E46_RS02195	COG1640	4-alpha-glucanotransferase
C9E46_RS02200	COG2610	gluconate transmembrane transporter activity
C9E46_RS02210	COG1040	competence protein
C9E46_RS02220	COG5464	transposase or invertase
C9E46_RS02230	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
C9E46_RS02235	COG1918	ferrous iron import across plasma membrane
C9E46_RS02240	COG2183	response to ionizing radiation
C9E46_RS02245	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C9E46_RS02265	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
C9E46_RS02275	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C9E46_RS02280	COG1011	Hydrolase
C9E46_RS02290	COG0494	nUDIX hydrolase
C9E46_RS02295	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
C9E46_RS02300	COG4972	Pilus assembly protein
C9E46_RS02305	COG3166	PFAM Fimbrial assembly family protein
C9E46_RS02320	COG4796	Type ii and iii secretion system protein
C9E46_RS02335	COG3266	domain, Protein
C9E46_RS02340	COG0338	D12 class N6 adenine-specific DNA methyltransferase
C9E46_RS02345	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C9E46_RS02350	COG0546	phosphoglycolate phosphatase activity
C9E46_RS02355	COG0180	Tryptophanyl-tRNA synthetase
C9E46_RS02360	COG2188	Transcriptional regulator
C9E46_RS02370	COG1082	Xylose isomerase domain protein TIM barrel
C9E46_RS02375	COG2222	sugar isomerase
C9E46_RS02380	COG0531	amino acid
C9E46_RS02395	COG2116	formate transmembrane transporter activity
C9E46_RS02400	COG2146	nitrite reductase [NAD(P)H] activity
C9E46_RS02405	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C9E46_RS02420	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C9E46_RS02430	COG2184	nucleotidyltransferase activity
C9E46_RS02435	COG0512	Glutamine amidotransferase of anthranilate synthase
C9E46_RS02440	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C9E46_RS02445	COG1289	transmembrane transporter activity
C9E46_RS02450	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C9E46_RS02455	COG1765	OsmC-like protein
C9E46_RS02460	COG3954	Phosphoribulokinase
C9E46_RS02470	COG0429	hydrolase of the alpha beta-hydrolase fold
C9E46_RS02475	COG0488	(ABC) transporter
C9E46_RS02490	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
C9E46_RS02495	COG1047	Peptidyl-prolyl cis-trans
C9E46_RS02505	COG0545	Peptidyl-prolyl cis-trans isomerase
C9E46_RS02510	COG2964	Protein conserved in bacteria
C9E46_RS02585	COG0089	rRNA binding
C9E46_RS02675	COG0201	protein transport
C9E46_RS02715	COG0789	Transcriptional regulator
C9E46_RS02720	COG3036	rescue of stalled ribosome
C9E46_RS02730	COG0569	domain protein
C9E46_RS02750	COG0758	DNA mediated transformation
C9E46_RS02760	COG0551	DNA topoisomerase type I activity
C9E46_RS02765	COG0009	L-threonylcarbamoyladenylate synthase
C9E46_RS02780	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C9E46_RS02825	COG1126	abc transporter atp-binding protein
C9E46_RS02835	COG4597	amino acid ABC transporter
C9E46_RS02840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9E46_RS02855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C9E46_RS02860	COG1309	transcriptional regulator
C9E46_RS02870	COG2189	Belongs to the N(4) N(6)-methyltransferase family
C9E46_RS02880	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C9E46_RS02890	COG4145	pantothenate transmembrane transporter activity
C9E46_RS02895	COG3924	membrane
C9E46_RS02900	COG0439	Biotin carboxylase
C9E46_RS02905	COG0511	ligase activity, forming carbon-carbon bonds
C9E46_RS02910	COG0604	alcohol dehydrogenase
C9E46_RS02915	COG2200	EAL domain
C9E46_RS02915	COG2199	diguanylate cyclase activity
C9E46_RS02920	COG1077	Cell shape determining protein MreB Mrl
C9E46_RS02925	COG1792	Involved in formation and maintenance of cell shape
C9E46_RS02930	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C9E46_RS02935	COG0424	maF-like protein
C9E46_RS02940	COG1530	ribonuclease E activity
C9E46_RS02945	COG3164	Protein of unknown function
C9E46_RS02950	COG0312	modulator of DNA gyrase
C9E46_RS02955	COG0583	DNA-binding transcription factor activity
C9E46_RS02975	COG2732	(Barnase) inhibitor
C9E46_RS02995	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C9E46_RS03000	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C9E46_RS03005	COG3105	Protein conserved in bacteria
C9E46_RS03010	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
C9E46_RS03030	COG0625	glutathione transferase activity
C9E46_RS03035	COG2969	positive regulation of protein catabolic process
C9E46_RS03040	COG3069	C4-dicarboxylate transmembrane transporter activity
C9E46_RS03070	COG2731	YhcH YjgK YiaL family protein
C9E46_RS03075	COG4804	nuclease activity
C9E46_RS03080	COG0493	'glutamate synthase
C9E46_RS03085	COG0070	glutamate synthase
C9E46_RS03085	COG0069	glutamate synthase activity
C9E46_RS03085	COG0067	glutamate synthase
C9E46_RS03090	COG1242	4 iron, 4 sulfur cluster binding
C9E46_RS03095	COG5002	protein histidine kinase activity
C9E46_RS03095	COG2198	Histidine kinase
C9E46_RS03095	COG0784	Response regulator, receiver
C9E46_RS03100	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
C9E46_RS03110	COG0515	serine threonine protein kinase
C9E46_RS03115	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9E46_RS03130	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C9E46_RS03135	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C9E46_RS03140	COG1137	ATPase activity
C9E46_RS03145	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
C9E46_RS03150	COG3117	lipopolysaccharide transmembrane transporter activity
C9E46_RS03155	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
C9E46_RS03160	COG0517	IMP dehydrogenase activity
C9E46_RS03160	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C9E46_RS03165	COG0530	calcium, potassium:sodium antiporter activity
C9E46_RS03170	COG1127	ABC transporter
C9E46_RS03175	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C9E46_RS03180	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C9E46_RS03185	COG2854	intermembrane phospholipid transfer
C9E46_RS03190	COG3113	response to antibiotic
C9E46_RS03195	COG5007	Belongs to the BolA IbaG family
C9E46_RS03205	COG3423	Transcriptional regulator
C9E46_RS03210	COG0142	geranyltranstransferase activity
C9E46_RS03225	COG0697	spore germination
C9E46_RS03235	COG2027	D-alanyl-D-alanine carboxypeptidase
C9E46_RS03240	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C9E46_RS03245	COG1534	Rna-binding protein
C9E46_RS03255	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C9E46_RS03260	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C9E46_RS03270	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C9E46_RS03280	COG2194	sulfuric ester hydrolase activity
C9E46_RS03300	COG0195	Participates in both transcription termination and antitermination
C9E46_RS03340	COG0513	Belongs to the DEAD box helicase family
C9E46_RS03345	COG0814	amino acid
C9E46_RS03350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C9E46_RS03355	COG0826	peptidase U32
C9E46_RS03360	COG0826	peptidase U32
C9E46_RS03365	COG3154	lipid carrier protein
C9E46_RS03370	COG3153	acetyltransferase
C9E46_RS03380	COG3787	Belongs to the UPF0306 family
C9E46_RS03385	COG0693	protein deglycase activity
C9E46_RS03390	COG0702	epimerase
C9E46_RS03395	COG0701	Predicted permease
C9E46_RS03400	COG2823	Periplasmic or secreted lipoprotein
C9E46_RS03420	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C9E46_RS03425	COG3539	Fimbrial protein
C9E46_RS03435	COG3539	Fimbrial protein
C9E46_RS03440	COG3188	usher protein
C9E46_RS03445	COG3121	Chaperone
C9E46_RS03450	COG3539	Fimbrial protein
C9E46_RS03460	COG3716	PTS system mannose fructose sorbose family IID component
C9E46_RS03470	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C9E46_RS03480	COG2222	sugar isomerase
C9E46_RS03485	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C9E46_RS03490	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9E46_RS03495	COG3716	PTS system mannose fructose sorbose family IID component
C9E46_RS03505	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C9E46_RS03515	COG1349	DNA-binding transcription factor activity
C9E46_RS03525	COG2002	toxin-antitoxin pair type II binding
C9E46_RS03530	COG2721	sulfolactate sulfo-lyase activity
C9E46_RS03535	COG2271	Major facilitator Superfamily
C9E46_RS03545	COG2084	Dehydrogenase
C9E46_RS03550	COG1929	Belongs to the glycerate kinase type-1 family
C9E46_RS03575	COG0583	DNA-binding transcription factor activity
C9E46_RS03580	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C9E46_RS03590	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C9E46_RS03595	COG1882	Formate acetyltransferase
C9E46_RS03600	COG0251	oxidation-reduction process
C9E46_RS03605	COG1760	l-serine dehydratase
C9E46_RS03610	COG0814	amino acid
C9E46_RS03625	COG1741	Belongs to the pirin family
C9E46_RS03630	COG0583	DNA-binding transcription factor activity
C9E46_RS03635	COG3152	Membrane
C9E46_RS03640	COG3152	Membrane
C9E46_RS03645	COG0435	Glutathione S-transferase
C9E46_RS03650	COG2259	Doxx family
C9E46_RS03660	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
C9E46_RS03665	COG4575	ribosome binding
C9E46_RS03670	COG1422	Protein of unknown function (DUF1090)
C9E46_RS03680	COG0586	Pfam SNARE associated Golgi protein
C9E46_RS03685	COG2186	Transcriptional regulator
C9E46_RS03690	COG2271	Major facilitator Superfamily
C9E46_RS03700	COG2721	sulfolactate sulfo-lyase activity
C9E46_RS03710	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
C9E46_RS03715	COG0861	Integral membrane protein TerC family
C9E46_RS03720	COG0673	inositol 2-dehydrogenase activity
C9E46_RS03725	COG2949	membrane
C9E46_RS03730	COG1451	nucleotide metabolic process
C9E46_RS03740	COG4680	protein conserved in bacteria
C9E46_RS03745	COG5499	transcription regulator containing HTH domain
C9E46_RS03750	COG1902	pentaerythritol trinitrate reductase activity
C9E46_RS03750	COG0446	pyridine nucleotide-disulphide oxidoreductase
C9E46_RS03755	COG3408	Glycogen debranching enzyme
C9E46_RS03755	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
C9E46_RS03765	COG0531	amino acid
C9E46_RS03770	COG2731	YhcH YjgK YiaL family protein
C9E46_RS03775	COG3250	beta-galactosidase activity
C9E46_RS03780	COG1609	Transcriptional regulator
C9E46_RS03785	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C9E46_RS03795	COG0840	transmembrane signaling receptor activity
C9E46_RS03800	COG1695	Transcriptional regulator
C9E46_RS03805	COG2375	cellular response to nickel ion
C9E46_RS03820	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C9E46_RS03825	COG0358	DNA primase activity
C9E46_RS03830	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C9E46_RS03840	COG0471	metal ion transport
C9E46_RS03845	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C9E46_RS03850	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C9E46_RS03855	COG0583	DNA-binding transcription factor activity
C9E46_RS03865	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C9E46_RS03880	COG4991	sh3 domain protein
C9E46_RS03885	COG3025	triphosphatase activity
C9E46_RS03910	COG2268	Band 7 protein
C9E46_RS03915	COG1585	Membrane protein implicated in regulation of membrane protease activity
C9E46_RS03940	COG3384	dioxygenase
C9E46_RS03945	COG0754	glutathionylspermidine amidase activity
C9E46_RS03955	COG1538	Outer membrane efflux protein
C9E46_RS03960	COG0494	nUDIX hydrolase
C9E46_RS03965	COG3151	Protein conserved in bacteria
C9E46_RS03970	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C9E46_RS03975	COG3150	esterase
C9E46_RS03980	COG0187	DNA topoisomerase II activity
C9E46_RS03985	COG4774	siderophore transport
C9E46_RS03990	COG1120	ATPase activity
C9E46_RS03995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C9E46_RS04000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C9E46_RS04010	COG1737	Transcriptional regulator
C9E46_RS04015	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C9E46_RS04020	COG2249	NAD(P)H dehydrogenase (quinone) activity
C9E46_RS04025	COG0642	Histidine kinase
C9E46_RS04030	COG0745	RESPONSE REGULATOR receiver
C9E46_RS04035	COG3111	PFAM Bacterial OB fold (BOF) protein
C9E46_RS04040	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
C9E46_RS04045	COG4166	transmembrane transport
C9E46_RS04050	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C9E46_RS04055	COG0204	Acyl-transferase
C9E46_RS04060	COG2132	Multicopper oxidase
C9E46_RS04065	COG1032	radical SAM domain protein
C9E46_RS04070	COG4238	major outer membrane lipoprotein
C9E46_RS04080	COG0656	L-ascorbic acid biosynthetic process
C9E46_RS04085	COG1979	alcohol dehydrogenase
C9E46_RS04090	COG2207	Transcriptional regulator
C9E46_RS04095	COG0586	Pfam SNARE associated Golgi protein
C9E46_RS04100	COG0626	cystathionine gamma-synthase activity
C9E46_RS04105	COG0811	peptide transport
C9E46_RS04110	COG0848	biopolymer transport protein
C9E46_RS04115	COG1028	Short-chain dehydrogenase reductase Sdr
C9E46_RS04125	COG0667	Aldo Keto reductase
C9E46_RS04140	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
C9E46_RS04145	COG0437	4 iron, 4 sulfur cluster binding
C9E46_RS04150	COG5557	Pfam Polysulphide reductase, NrfD
C9E46_RS04155	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
C9E46_RS04160	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C9E46_RS04165	COG1773	rubredoxin
C9E46_RS04170	COG0375	protein maturation
C9E46_RS04175	COG0298	carbon dioxide binding
C9E46_RS04180	COG0625	glutathione transferase activity
C9E46_RS04185	COG0754	glutathionylspermidine amidase activity
C9E46_RS04210	COG3436	PFAM IS66 Orf2 family protein
C9E46_RS04220	COG4372	Transposase
C9E46_RS04225	COG3436	PFAM IS66 Orf2 family protein
C9E46_RS04310	COG3436	PFAM IS66 Orf2 family protein
C9E46_RS04330	COG0582	viral genome integration into host DNA
C9E46_RS04340	COG1811	Na channel or pump
C9E46_RS04345	COG1982	Orn Lys Arg decarboxylase major
C9E46_RS04350	COG2211	Major facilitator Superfamily
C9E46_RS04365	COG1194	a g-specific adenine glycosylase
C9E46_RS04375	COG3171	Protein conserved in bacteria
C9E46_RS04385	COG0252	asparaginase activity
C9E46_RS04395	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C9E46_RS04400	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C9E46_RS04410	COG0762	integral membrane protein
C9E46_RS04415	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C9E46_RS04420	COG2805	Type II/IV secretion system protein
C9E46_RS04435	COG0189	ligase activity
C9E46_RS04440	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C9E46_RS04445	COG2356	endonuclease I
C9E46_RS04450	COG3091	SprT-like family
C9E46_RS04455	COG2814	Major facilitator Superfamily
C9E46_RS04470	COG1166	arginine decarboxylase activity
C9E46_RS04485	COG0501	Belongs to the peptidase M48B family
C9E46_RS04490	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C9E46_RS04495	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9E46_RS04500	COG2213	PTS system mannitol-specific
C9E46_RS04505	COG1063	alcohol dehydrogenase
C9E46_RS04510	COG1494	fructose-1,6-bisphosphatase
C9E46_RS04520	COG1072	(Pantothenic acid kinase))
C9E46_RS04525	COG1122	ATPase activity
C9E46_RS04530	COG1122	ATPase activity
C9E46_RS04555	COG0126	phosphoglycerate kinase activity
C9E46_RS04560	COG0191	fructose-bisphosphate aldolase activity
C9E46_RS04565	COG0668	transmembrane transport
C9E46_RS04575	COG2968	Membrane
C9E46_RS04580	COG0583	DNA-binding transcription factor activity
C9E46_RS04585	COG0583	DNA-binding transcription factor activity
C9E46_RS04600	COG1703	isobutyryl-CoA mutase activity
C9E46_RS04605	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C9E46_RS04605	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C9E46_RS04620	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C9E46_RS04635	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C9E46_RS04655	COG0006	proline dipeptidase activity
C9E46_RS04660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C9E46_RS04665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C9E46_RS04690	COG2723	6-phospho-beta-galactosidase activity
C9E46_RS04700	COG1272	protein, Hemolysin III
C9E46_RS04710	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
C9E46_RS04720	COG0716	FMN binding
C9E46_RS04725	COG4974	Belongs to the 'phage' integrase family
C9E46_RS04730	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C9E46_RS04735	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C9E46_RS04745	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C9E46_RS04765	COG2233	PERMEase
C9E46_RS04770	COG0493	'glutamate synthase
C9E46_RS04770	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C9E46_RS04780	COG2252	PERMEase
C9E46_RS04785	COG0402	S-adenosylhomocysteine deaminase activity
C9E46_RS04790	COG2233	PERMEase
C9E46_RS04795	COG2080	2 iron, 2 sulfur cluster binding
C9E46_RS04795	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C9E46_RS04800	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C9E46_RS04805	COG0402	S-adenosylhomocysteine deaminase activity
C9E46_RS04810	COG0493	'glutamate synthase
C9E46_RS04810	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C9E46_RS04815	COG2068	MobA-Related Protein
C9E46_RS04820	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C9E46_RS04825	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C9E46_RS04825	COG3608	succinylglutamate desuccinylase aspartoacylase
C9E46_RS04830	COG0549	Belongs to the carbamate kinase family
C9E46_RS04840	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C9E46_RS04845	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C9E46_RS04850	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C9E46_RS04855	COG3829	transcription factor binding
C9E46_RS04860	COG2080	2 iron, 2 sulfur cluster binding
C9E46_RS04865	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C9E46_RS04870	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C9E46_RS04875	COG4942	peptidase
C9E46_RS04895	COG2207	Transcriptional regulator
C9E46_RS05010	COG0741	lytic transglycosylase activity
C9E46_RS05020	COG3710	Transcriptional regulator
C9E46_RS05020	COG0457	Tetratricopeptide repeat
C9E46_RS05030	COG0457	Tetratricopeptide repeat
C9E46_RS05055	COG3710	Transcriptional regulator
C9E46_RS05060	COG2771	luxR family
C9E46_RS05065	COG0814	amino acid
C9E46_RS05070	COG0183	Belongs to the thiolase family
C9E46_RS05080	COG1028	Short-chain dehydrogenase reductase Sdr
C9E46_RS05085	COG2814	Major facilitator Superfamily
C9E46_RS05090	COG1794	racemase activity, acting on amino acids and derivatives
C9E46_RS05095	COG0583	DNA-binding transcription factor activity
C9E46_RS05105	COG1609	Transcriptional regulator
C9E46_RS05125	COG0667	Aldo Keto reductase
C9E46_RS05135	COG0861	Integral membrane protein TerC family
C9E46_RS05155	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
C9E46_RS05170	COG2165	general secretion pathway protein
C9E46_RS05175	COG4795	General secretion pathway protein
C9E46_RS05185	COG4967	type IV pilus modification protein PilV
C9E46_RS05190	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
C9E46_RS05195	COG1025	Belongs to the peptidase M16 family
C9E46_RS05200	COG1074	ATP-dependent DNA helicase activity
C9E46_RS05205	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C9E46_RS05210	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C9E46_RS05210	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C9E46_RS05215	COG0860	N-Acetylmuramoyl-L-alanine amidase
C9E46_RS05235	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
C9E46_RS05240	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C9E46_RS05245	COG2166	iron-sulfur cluster assembly
C9E46_RS05250	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C9E46_RS05260	COG0583	DNA-binding transcription factor activity
C9E46_RS05265	COG2363	Small membrane protein
C9E46_RS05275	COG1349	DNA-binding transcription factor activity
C9E46_RS05285	COG1070	Carbohydrate kinase
C9E46_RS05295	COG0738	Major facilitator superfamily
C9E46_RS05300	COG0235	Class ii aldolase
C9E46_RS05305	COG1454	alcohol dehydrogenase
C9E46_RS05315	COG1760	l-serine dehydratase
C9E46_RS05320	COG0814	amino acid
C9E46_RS05325	COG1611	Belongs to the LOG family
C9E46_RS05340	COG3098	single-species biofilm formation
C9E46_RS05345	COG0564	pseudouridine synthase activity
C9E46_RS05350	COG0716	FMN binding
C9E46_RS05355	COG2271	Major facilitator Superfamily
C9E46_RS05360	COG4948	Mandelate Racemase Muconate Lactonizing
C9E46_RS05365	COG4948	Mandelate Racemase Muconate Lactonizing
C9E46_RS05370	COG4948	Mandelate Racemase Muconate Lactonizing
C9E46_RS05375	COG2205	protein histidine kinase activity
C9E46_RS05375	COG3437	response regulator, receiver
C9E46_RS05375	COG3850	Histidine kinase
C9E46_RS05375	COG4999	Histidine kinase
C9E46_RS05380	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C9E46_RS05385	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C9E46_RS05390	COG2336	PFAM SpoVT AbrB
C9E46_RS05395	COG2337	Toxic component of a toxin-antitoxin (TA) module
C9E46_RS05400	COG3956	TIGRFAM MazG family protein
C9E46_RS05415	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
C9E46_RS05425	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
C9E46_RS05435	COG0602	queuosine metabolic process
C9E46_RS05440	COG1070	Carbohydrate kinase
C9E46_RS05445	COG2223	nitrite transmembrane transporter activity
C9E46_RS05450	COG1028	Short-chain dehydrogenase reductase Sdr
C9E46_RS05455	COG0277	FAD linked oxidase domain protein
C9E46_RS05465	COG2086	electron transfer activity
C9E46_RS05475	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
C9E46_RS05480	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C9E46_RS05485	COG0644	oxidoreductase
C9E46_RS05490	COG0720	synthase
C9E46_RS05495	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C9E46_RS05520	COG1203	CRISPR-associated helicase, Cas3
C9E46_RS05535	COG1857	crispr-associated protein
C9E46_RS05550	COG1518	maintenance of DNA repeat elements
C9E46_RS05555	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C9E46_RS05560	COG2234	aminopeptidase activity
C9E46_RS05615	COG1388	LysM domain
C9E46_RS05615	COG4942	peptidase
C9E46_RS05620	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C9E46_RS05625	COG1846	Transcriptional regulator
C9E46_RS05630	COG0163	prenyltransferase activity
C9E46_RS05635	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C9E46_RS05645	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C9E46_RS05660	COG3604	Transcriptional regulator
C9E46_RS05665	COG0309	Hydrogenase expression formation protein (HypE)
C9E46_RS05670	COG0409	Hydrogenase expression formation protein
C9E46_RS05675	COG0298	carbon dioxide binding
C9E46_RS05680	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
C9E46_RS05685	COG0375	protein maturation
C9E46_RS05695	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C9E46_RS05700	COG0651	ATP synthesis coupled electron transport
C9E46_RS05705	COG0650	Formate hydrogenlyase subunit 4
C9E46_RS05710	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
C9E46_RS05710	COG3261	NADH dehydrogenase
C9E46_RS05715	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C9E46_RS05720	COG3260	NADH ubiquinone oxidoreductase 20
C9E46_RS05730	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C9E46_RS05735	COG2723	6-phospho-beta-galactosidase activity
C9E46_RS05740	COG1263	PTS System
C9E46_RS05740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C9E46_RS05745	COG1609	Transcriptional regulator
C9E46_RS05750	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C9E46_RS05755	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
C9E46_RS05775	COG0517	IMP dehydrogenase activity
C9E46_RS05775	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C9E46_RS05780	COG1349	DNA-binding transcription factor activity
C9E46_RS05785	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9E46_RS05790	COG1028	Short-chain dehydrogenase reductase Sdr
C9E46_RS05810	COG2951	lytic endotransglycosylase activity
C9E46_RS05815	COG1546	Belongs to the CinA family
C9E46_RS05830	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C9E46_RS05835	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
C9E46_RS05865	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C9E46_RS05870	COG1238	metal cluster binding
C9E46_RS05885	COG2814	Major facilitator Superfamily
C9E46_RS05890	COG1566	PFAM secretion protein HlyD family protein
C9E46_RS05895	COG1846	Transcriptional regulator
C9E46_RS05905	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
C9E46_RS05910	COG2814	Major facilitator Superfamily
C9E46_RS05915	COG2113	Glycine betaine
C9E46_RS05920	COG4176	ABC-type proline glycine betaine transport system permease component
C9E46_RS05925	COG4175	Glycine betaine
C9E46_RS05930	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C9E46_RS05935	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C9E46_RS05945	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C9E46_RS05955	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C9E46_RS05965	COG4575	ribosome binding
C9E46_RS05980	COG2916	Histone family protein nucleoid-structuring protein H-NS
C9E46_RS05985	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C9E46_RS05990	COG0640	Transcriptional regulator
C9E46_RS05995	COG0401	homolog of Blt101
C9E46_RS06000	COG1652	LysM domain
C9E46_RS06005	COG1802	Transcriptional regulator
C9E46_RS06010	COG1113	amino acid transport
C9E46_RS06015	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C9E46_RS06020	COG1012	belongs to the aldehyde dehydrogenase family
C9E46_RS06025	COG0579	oxidoreductase
C9E46_RS06110	COG2826	transposase and inactivated derivatives, IS30 family
C9E46_RS06170	COG3436	PFAM IS66 Orf2 family protein
C9E46_RS06205	COG0727	PFAM Uncharacterised protein family (UPF0153)
C9E46_RS06230	COG2867	negative regulation of translational initiation
C9E46_RS06240	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C9E46_RS06245	COG0497	DNA recombination
C9E46_RS06260	COG4536	flavin adenine dinucleotide binding
C9E46_RS06265	COG4137	Cytochrome C assembly protein
C9E46_RS06270	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C9E46_RS06295	COG2885	chlorophyll binding
C9E46_RS06300	COG2199	diguanylate cyclase activity
C9E46_RS06315	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C9E46_RS06320	COG1605	Chorismate mutase
C9E46_RS06320	COG0287	Prephenate dehydrogenase
C9E46_RS06325	COG0077	Prephenate dehydratase
C9E46_RS06325	COG1605	Chorismate mutase
C9E46_RS06335	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C9E46_RS06340	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C9E46_RS06345	COG0564	pseudouridine synthase activity
C9E46_RS06355	COG0542	response to heat
C9E46_RS06380	COG0477	Major facilitator Superfamily
C9E46_RS06385	COG5544	Lipoprotein
C9E46_RS06390	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C9E46_RS06395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C9E46_RS06395	COG1042	CoA-binding domain protein
C9E46_RS06395	COG0045	succinate-CoA ligase (ADP-forming) activity
C9E46_RS06400	COG3148	PFAM DTW domain containing protein
C9E46_RS06405	COG3118	belongs to the thioredoxin family
C9E46_RS06410	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C9E46_RS06425	COG1280	lysine exporter protein (LysE YggA)
C9E46_RS06430	COG0583	DNA-binding transcription factor activity
C9E46_RS06435	COG0513	Belongs to the DEAD box helicase family
C9E46_RS06440	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C9E46_RS06445	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C9E46_RS06455	COG1595	DNA-templated transcription, initiation
C9E46_RS06460	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
C9E46_RS06465	COG3026	antisigma factor binding
C9E46_RS06470	COG3086	response to oxidative stress
C9E46_RS06480	COG0681	Belongs to the peptidase S26 family
C9E46_RS06500	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
C9E46_RS06515	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C9E46_RS06520	COG1737	Transcriptional regulator
C9E46_RS06525	COG0560	Phosphoserine phosphatase
C9E46_RS06530	COG0590	tRNA wobble adenosine to inosine editing
C9E46_RS06535	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
C9E46_RS06540	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C9E46_RS06540	COG0047	phosphoribosylformylglycinamidine synthase activity
C9E46_RS06545	COG2205	protein histidine kinase activity
C9E46_RS06550	COG3170	Tfp pilus assembly protein FimV
C9E46_RS06555	COG2204	response regulator
C9E46_RS06560	COG0347	Belongs to the P(II) protein family
C9E46_RS06565	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C9E46_RS06565	COG1017	nitric oxide dioxygenase activity
C9E46_RS06575	COG1940	carbohydrate kinase activity
C9E46_RS06585	COG1940	carbohydrate kinase activity
C9E46_RS06590	COG0457	Tetratricopeptide repeat
C9E46_RS06595	COG1879	ABC-type sugar transport system periplasmic component
C9E46_RS06600	COG1129	ABC transporter
C9E46_RS06605	COG1172	Belongs to the binding-protein-dependent transport system permease family
C9E46_RS06615	COG2017	converts alpha-aldose to the beta-anomer
C9E46_RS06620	COG2259	Doxx family
C9E46_RS06645	COG4638	Rieske (2fe-2S)
C9E46_RS06650	COG0583	DNA-binding transcription factor activity
C9E46_RS06655	COG2814	Major facilitator Superfamily
C9E46_RS06660	COG3711	transcriptional antiterminator
C9E46_RS06665	COG1073	alpha beta
C9E46_RS06670	COG0483	inositol monophosphate 1-phosphatase activity
C9E46_RS06690	COG0822	iron-sulfur transferase activity
C9E46_RS06710	COG0633	Ferredoxin
C9E46_RS06715	COG2975	iron-sulfur cluster assembly
C9E46_RS06730	COG2897	thiosulfate sulfurtransferase activity
C9E46_RS06735	COG2373	Large extracellular alpha-helical protein
C9E46_RS06740	COG4953	penicillin-binding protein 1C
C9E46_RS06745	COG0243	molybdopterin cofactor binding
C9E46_RS06750	COG0437	4 iron, 4 sulfur cluster binding
C9E46_RS06755	COG3302	dmso reductase anchor subunit
C9E46_RS06790	COG2976	Protein conserved in bacteria
C9E46_RS06805	COG1645	bacterial-type flagellum-dependent swarming motility
C9E46_RS06815	COG0516	GMP reductase activity
C9E46_RS06815	COG0517	IMP dehydrogenase activity
C9E46_RS06830	COG3133	Outer membrane lipoprotein
C9E46_RS06840	COG2200	EAL domain
C9E46_RS06845	COG0248	Ppx GppA phosphatase
C9E46_RS06850	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
C9E46_RS06855	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C9E46_RS06870	COG2233	PERMEase
C9E46_RS06880	COG1393	Belongs to the ArsC family
C9E46_RS06885	COG4783	chaperone-mediated protein folding
C9E46_RS06890	COG0628	permease
C9E46_RS06895	COG2116	formate transmembrane transporter activity
C9E46_RS06900	COG3604	Transcriptional regulator
C9E46_RS06910	COG3260	NADH ubiquinone oxidoreductase 20
C9E46_RS06915	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C9E46_RS06920	COG3261	NADH dehydrogenase
C9E46_RS06920	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
C9E46_RS06925	COG0651	ATP synthesis coupled electron transport
C9E46_RS06930	COG4237	Hydrogenase 4 membrane
C9E46_RS06935	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C9E46_RS06940	COG0650	Formate hydrogenlyase subunit 4
C9E46_RS06945	COG0651	ATP synthesis coupled electron transport
C9E46_RS06950	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C9E46_RS06955	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C9E46_RS06960	COG2716	regulation of RNA biosynthetic process
C9E46_RS06970	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
C9E46_RS06980	COG2321	neutral zinc metallopeptidase
C9E46_RS06990	COG0400	carboxylic ester hydrolase activity
C9E46_RS07005	COG1393	Belongs to the ArsC family
C9E46_RS07020	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C9E46_RS07025	COG3850	Histidine kinase
C9E46_RS07030	COG0493	'glutamate synthase
C9E46_RS07030	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C9E46_RS07040	COG5342	invasion associated locus B
C9E46_RS07045	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C9E46_RS07050	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C9E46_RS07055	COG0280	phosphate acetyltransferase
C9E46_RS07055	COG0281	malic enzyme
C9E46_RS07060	COG4810	utilization protein
C9E46_RS07065	COG4917	ethanolamine utilization protein
C9E46_RS07070	COG4766	ethanolamine catabolic process
C9E46_RS07075	COG4812	Cobalamin adenosyltransferase
C9E46_RS07080	COG0280	phosphate acetyltransferase
C9E46_RS07085	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
C9E46_RS07090	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
C9E46_RS07095	COG1012	belongs to the aldehyde dehydrogenase family
C9E46_RS07100	COG4820	ethanolamine utilization protein (EutJ)
C9E46_RS07105	COG1454	alcohol dehydrogenase
C9E46_RS07110	COG3192	ethanolamine utilization protein
C9E46_RS07115	COG4819	ethanolamine utilization protein
C9E46_RS07120	COG4819	ethanolamine utilization protein
C9E46_RS07125	COG4303	Ethanolamine ammonia lyase large subunit
C9E46_RS07135	COG4816	utilization protein
C9E46_RS07140	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
C9E46_RS07145	COG2207	Transcriptional regulator
C9E46_RS07155	COG0860	N-Acetylmuramoyl-L-alanine amidase
C9E46_RS07175	COG2837	iron assimilation
C9E46_RS07180	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C9E46_RS07185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C9E46_RS07185	COG1263	PTS System
C9E46_RS07200	COG1028	Short-chain dehydrogenase reductase Sdr
C9E46_RS07205	COG4150	thiosulfate binding
C9E46_RS07210	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
C9E46_RS07215	COG4208	sulfate ABC transporter
C9E46_RS07220	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C9E46_RS07225	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C9E46_RS07240	COG2190	(PTS) system
C9E46_RS07245	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C9E46_RS07250	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9E46_RS07255	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C9E46_RS07275	COG3530	Putative quorum-sensing-regulated virulence factor
C9E46_RS07280	COG0385	Bile acid
C9E46_RS07285	COG0583	DNA-binding transcription factor activity
C9E46_RS07330	COG0675	Transposase, IS605 OrfB family
C9E46_RS07335	COG3415	Transposase
C9E46_RS07340	COG3415	Transposase
C9E46_RS07355	COG2199	diguanylate cyclase activity
C9E46_RS07355	COG2200	EAL domain
C9E46_RS07360	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C9E46_RS07385	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C9E46_RS07390	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C9E46_RS07395	COG0006	proline dipeptidase activity
C9E46_RS07400	COG1363	Peptidase, m42
C9E46_RS07405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9E46_RS07405	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C9E46_RS07405	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9E46_RS07410	COG2207	Transcriptional regulator
C9E46_RS07415	COG3279	Response regulator of the LytR AlgR family
C9E46_RS07420	COG3275	phosphorelay sensor kinase activity
C9E46_RS07425	COG0436	Aminotransferase
C9E46_RS07435	COG1560	Kdo2-lipid A biosynthetic process
C9E46_RS07460	COG0028	Belongs to the TPP enzyme family
C9E46_RS07465	COG0679	Auxin Efflux Carrier
C9E46_RS07470	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C9E46_RS07475	COG2198	Histidine kinase
C9E46_RS07475	COG2205	protein histidine kinase activity
C9E46_RS07475	COG0784	Response regulator, receiver
C9E46_RS07475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9E46_RS07480	COG2197	response regulator
C9E46_RS07485	COG1566	PFAM secretion protein HlyD family protein
C9E46_RS07490	COG0477	Major facilitator Superfamily
C9E46_RS07565	COG0582	viral genome integration into host DNA
C9E46_RS07575	COG2116	formate transmembrane transporter activity
C9E46_RS07580	COG2853	Lipoprotein
C9E46_RS07595	COG2067	long-chain fatty acid transport protein
C9E46_RS07600	COG3691	Protein conserved in bacteria
C9E46_RS07615	COG2062	phosphohistidine phosphatase, SixA
C9E46_RS07620	COG3539	Fimbrial protein
C9E46_RS07625	COG3188	usher protein
C9E46_RS07630	COG3121	Chaperone
C9E46_RS07635	COG3539	Fimbrial protein
C9E46_RS07640	COG3539	Fimbrial protein
C9E46_RS07645	COG3539	Fimbrial protein
C9E46_RS07675	COG0730	response to heat
C9E46_RS07680	COG3101	peptidyl-lysine hydroxylation
C9E46_RS07690	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
C9E46_RS07690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C9E46_RS07695	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C9E46_RS07700	COG2814	Major facilitator Superfamily
C9E46_RS07715	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C9E46_RS07725	COG0586	Pfam SNARE associated Golgi protein
C9E46_RS07735	COG0285	dihydrofolate synthase activity
C9E46_RS07740	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
C9E46_RS07745	COG1286	toxin biosynthetic process
C9E46_RS07750	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C9E46_RS07755	COG0163	prenyltransferase activity
C9E46_RS07760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9E46_RS07765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9E46_RS07770	COG4215	(ABC) transporter
C9E46_RS07775	COG4160	amino acid transport
C9E46_RS07780	COG4598	ABC transporter
C9E46_RS07785	COG5464	transposase or invertase
C9E46_RS07790	COG1090	epimerase
C9E46_RS07795	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C9E46_RS07800	COG0625	glutathione transferase activity
C9E46_RS07805	COG0625	glutathione transferase activity
C9E46_RS07810	COG0622	Phosphoesterase
C9E46_RS07815	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
C9E46_RS07820	COG1288	antiporter activity
C9E46_RS07825	COG0857	belongs to the CobB CobQ family
C9E46_RS07825	COG0280	phosphate acetyltransferase
C9E46_RS07830	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C9E46_RS07845	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C9E46_RS07850	COG0471	metal ion transport
C9E46_RS07850	COG0490	domain, Protein
C9E46_RS07860	COG0436	Aminotransferase
C9E46_RS07865	COG0583	DNA-binding transcription factor activity
C9E46_RS07885	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
C9E46_RS07890	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
C9E46_RS07895	COG1034	ATP synthesis coupled electron transport
C9E46_RS07910	COG0839	Belongs to the complex I subunit 6 family
C9E46_RS07920	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C9E46_RS07925	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C9E46_RS07945	COG5160	protein modification by small protein removal
C9E46_RS07950	COG1234	tRNA 3'-trailer cleavage
C9E46_RS07955	COG2153	protein acetylation
C9E46_RS07960	COG4575	ribosome binding
C9E46_RS07965	COG1169	isochorismate synthase
C9E46_RS07980	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C9E46_RS07990	COG0318	PFAM AMP-dependent synthetase and ligase
C9E46_RS08035	COG0406	alpha-ribazole phosphatase activity
C9E46_RS08055	COG1414	Transcriptional regulator
C9E46_RS08060	COG4948	Mandelate Racemase Muconate Lactonizing
C9E46_RS08065	COG2271	Major facilitator Superfamily
C9E46_RS08070	COG3836	Belongs to the HpcH HpaI aldolase family
C9E46_RS08075	COG5464	transposase or invertase
C9E46_RS08080	COG0247	lactate metabolic process
C9E46_RS08090	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C9E46_RS08095	COG2271	Major facilitator Superfamily
C9E46_RS08110	COG0583	DNA-binding transcription factor activity
C9E46_RS08115	COG2814	Major facilitator Superfamily
C9E46_RS08120	COG3642	lipopolysaccharide core region biosynthetic process
C9E46_RS08125	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C9E46_RS08130	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C9E46_RS08135	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C9E46_RS08140	COG3468	outer membrane autotransporter barrel domain protein
C9E46_RS08150	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C9E46_RS08155	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
C9E46_RS08160	COG3234	Protein of unknown function (DUF1175)
C9E46_RS08165	COG2373	Large extracellular alpha-helical protein
C9E46_RS08175	COG4676	Protein conserved in bacteria
C9E46_RS08180	COG2205	protein histidine kinase activity
C9E46_RS08180	COG0784	Response regulator, receiver
C9E46_RS08185	COG2197	response regulator
C9E46_RS08190	COG2198	Histidine kinase
C9E46_RS08190	COG0642	Histidine kinase
C9E46_RS08195	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C9E46_RS08200	COG1477	protein flavinylation
C9E46_RS08205	COG2169	Transcriptional regulator
C9E46_RS08205	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C9E46_RS08210	COG3145	DNA-N1-methyladenine dioxygenase activity
C9E46_RS08215	COG4615	Cyclic peptide transporter
C9E46_RS08230	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
C9E46_RS08230	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C9E46_RS08235	COG3062	negative regulation of establishment of protein localization
C9E46_RS08245	COG0437	4 iron, 4 sulfur cluster binding
C9E46_RS08250	COG0348	domain, Protein
C9E46_RS08255	COG3043	anaerobic respiration
C9E46_RS08260	COG3005	denitrification pathway
C9E46_RS08265	COG4133	protoheme IX ABC transporter activity
C9E46_RS08270	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C9E46_RS08275	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C9E46_RS08280	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C9E46_RS08290	COG1138	Cytochrome C-type biogenesis protein
C9E46_RS08295	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C9E46_RS08300	COG3088	subunit of a heme lyase
C9E46_RS08300	COG4235	cytochrome complex assembly
C9E46_RS08305	COG2197	response regulator
C9E46_RS08310	COG3468	outer membrane autotransporter barrel domain protein
C9E46_RS08320	COG3083	sulfuric ester hydrolase activity
C9E46_RS08340	COG1061	Type III restriction enzyme res subunit
C9E46_RS08345	COG1187	pseudouridine synthase activity
C9E46_RS08350	COG2814	Major facilitator Superfamily
C9E46_RS08360	COG4172	Belongs to the ABC transporter superfamily
C9E46_RS08365	COG4239	(ABC) transporter, permease
C9E46_RS08370	COG4174	ABC transporter (Permease)
C9E46_RS08375	COG4166	transmembrane transport
C9E46_RS08380	COG2200	EAL domain
C9E46_RS08385	COG0791	NLP P60 protein
C9E46_RS08390	COG0671	phosphoesterase, PA-phosphatase related
C9E46_RS08395	COG0523	cobalamin synthesis protein
C9E46_RS08400	COG0246	Mannitol dehydrogenase
C9E46_RS08415	COG2814	Major facilitator Superfamily
C9E46_RS08420	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9E46_RS08420	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9E46_RS08425	COG1105	Belongs to the carbohydrate kinase PfkB family
C9E46_RS08430	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
C9E46_RS08430	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C9E46_RS08430	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C9E46_RS08435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C9E46_RS08440	COG2313	pseudouridylate synthase activity
C9E46_RS08445	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C9E46_RS08450	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C9E46_RS08460	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C9E46_RS08465	COG1522	sequence-specific DNA binding
C9E46_RS08465	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C9E46_RS08475	COG2855	membrane
C9E46_RS08480	COG0583	DNA-binding transcription factor activity
C9E46_RS08485	COG0833	amino acid
C9E46_RS08490	COG4771	TonB-dependent receptor
C9E46_RS08495	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
C9E46_RS08505	COG2311	Membrane
C9E46_RS08510	COG1609	Transcriptional regulator
C9E46_RS08515	COG1879	ABC-type sugar transport system periplasmic component
C9E46_RS08520	COG1129	ABC transporter
C9E46_RS08525	COG4211	Belongs to the binding-protein-dependent transport system permease family
C9E46_RS08530	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
C9E46_RS08530	COG0167	dihydroorotate dehydrogenase activity
C9E46_RS08535	COG0493	'glutamate synthase
C9E46_RS08545	COG2949	membrane
C9E46_RS08555	COG1346	cytolysis
C9E46_RS08570	COG2271	Major facilitator Superfamily
C9E46_RS08585	COG0625	glutathione transferase activity
C9E46_RS08590	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C9E46_RS08595	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C9E46_RS08605	COG1538	Outer membrane efflux protein
C9E46_RS08610	COG1028	Short-chain dehydrogenase reductase Sdr
C9E46_RS08615	COG0586	Pfam SNARE associated Golgi protein
C9E46_RS08625	COG1686	Belongs to the peptidase S11 family
C9E46_RS08630	COG0277	FAD linked oxidase domain protein
C9E46_RS08635	COG1472	Belongs to the glycosyl hydrolase 3 family
C9E46_RS08640	COG1732	Glycine betaine
C9E46_RS08645	COG1174	glycine betaine transport
C9E46_RS08650	COG1125	glycine betaine transport
C9E46_RS08655	COG1174	glycine betaine transport
C9E46_RS08665	COG0789	Transcriptional regulator
C9E46_RS08670	COG0582	viral genome integration into host DNA
C9E46_RS08885	COG3772	lysozyme
C9E46_RS08935	COG0740	serine-type endopeptidase activity
C9E46_RS09010	COG5301	cellulose 1,4-beta-cellobiosidase activity
C9E46_RS09045	COG3275	phosphorelay sensor kinase activity
C9E46_RS09050	COG3279	Response regulator of the LytR AlgR family
C9E46_RS09055	COG4807	Protein conserved in bacteria
C9E46_RS09060	COG4808	Protein conserved in bacteria
C9E46_RS09065	COG4715	Zinc finger, swim domain protein
C9E46_RS09070	COG3552	Protein containing von Willebrand factor type A (VWA) domain
C9E46_RS09075	COG2425	protein containing a von Willebrand factor type A (vWA) domain
C9E46_RS09080	COG2425	protein containing a von Willebrand factor type A (vWA) domain
C9E46_RS09085	COG0714	Associated with various cellular activities
C9E46_RS09095	COG3831	ATPase activity
C9E46_RS09105	COG3831	ATPase activity
C9E46_RS09120	COG0489	protein tyrosine kinase activity
C9E46_RS09130	COG3539	Fimbrial protein
C9E46_RS09135	COG3121	Chaperone
C9E46_RS09140	COG3188	usher protein
C9E46_RS09145	COG3539	Fimbrial protein
C9E46_RS09150	COG5455	response to cobalt ion
C9E46_RS09155	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
C9E46_RS09190	COG0351	phosphomethylpyrimidine kinase
C9E46_RS09195	COG3757	hydrolase, family 25
C9E46_RS09200	COG2188	Transcriptional regulator
C9E46_RS09205	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C9E46_RS09210	COG1397	ADP-ribosylglycohydrolase
C9E46_RS09215	COG2211	Major facilitator Superfamily
C9E46_RS09220	COG1830	Aldolase
C9E46_RS09235	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9E46_RS09240	COG3414	Phosphotransferase system galactitol-specific IIB component
C9E46_RS09245	COG3775	system Galactitol-specific IIC component
C9E46_RS09250	COG1063	alcohol dehydrogenase
C9E46_RS09275	COG0826	peptidase U32
C9E46_RS09280	COG3422	double-strand break repair
C9E46_RS09285	COG0745	RESPONSE REGULATOR receiver
C9E46_RS09290	COG2205	protein histidine kinase activity
C9E46_RS09305	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C9E46_RS09330	COG4245	von Willebrand factor, type A
C9E46_RS09335	COG0631	protein serine/threonine phosphatase activity
C9E46_RS09340	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
C9E46_RS09345	COG0443	Heat shock 70 kDa protein
C9E46_RS09350	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C9E46_RS09360	COG0572	uridine kinase
C9E46_RS09370	COG2982	Protein involved in outer membrane biogenesis
C9E46_RS09385	COG1253	flavin adenine dinucleotide binding
C9E46_RS09390	COG1596	polysaccharide export
C9E46_RS09395	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C9E46_RS09400	COG0489	protein tyrosine kinase activity
C9E46_RS09400	COG3206	protein involved in exopolysaccharide biosynthesis
C9E46_RS09405	COG0463	Glycosyl transferase, family 2
C9E46_RS09410	COG1045	serine acetyltransferase
C9E46_RS09415	COG0438	transferase activity, transferring glycosyl groups
C9E46_RS09425	COG1216	Glycosyl transferase, family 2
C9E46_RS09430	COG0110	maltose O-acetyltransferase activity
C9E46_RS09435	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
C9E46_RS09440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C9E46_RS09445	COG1051	belongs to the nudix hydrolase family
C9E46_RS09450	COG0297	glycogen (starch) synthase activity
C9E46_RS09455	COG0662	Cupin 2, conserved barrel domain protein
C9E46_RS09455	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
C9E46_RS09460	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C9E46_RS09465	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C9E46_RS09470	COG2244	polysaccharide biosynthetic process
C9E46_RS09475	COG2327	Polysaccharide pyruvyl transferase
C9E46_RS09480	COG0438	transferase activity, transferring glycosyl groups
C9E46_RS09490	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C9E46_RS09495	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C9E46_RS09520	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C9E46_RS09530	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
C9E46_RS09535	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C9E46_RS09540	COG1051	belongs to the nudix hydrolase family
C9E46_RS09545	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
C9E46_RS09545	COG0662	Cupin 2, conserved barrel domain protein
C9E46_RS09550	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C9E46_RS09565	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C9E46_RS09570	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C9E46_RS09600	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C9E46_RS09605	COG0131	Imidazoleglycerol-phosphate dehydratase
C9E46_RS09605	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C9E46_RS09615	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C9E46_RS09630	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C9E46_RS09635	COG0583	DNA-binding transcription factor activity
C9E46_RS09645	COG0531	amino acid
C9E46_RS09650	COG2391	methyltransferase activity
C9E46_RS09655	COG0425	Belongs to the sulfur carrier protein TusA family
C9E46_RS09660	COG2925	Exonuclease
C9E46_RS09665	COG0582	viral genome integration into host DNA
C9E46_RS09925	COG3772	lysozyme
C9E46_RS10045	COG1185	polyribonucleotide nucleotidyltransferase activity
C9E46_RS10080	COG5301	cellulose 1,4-beta-cellobiosidase activity
C9E46_RS10090	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C9E46_RS10120	COG1686	Belongs to the peptidase S11 family
C9E46_RS10130	COG1289	transmembrane transporter activity
C9E46_RS10140	COG4917	ethanolamine utilization protein
C9E46_RS10175	COG2003	Belongs to the UPF0758 family
C9E46_RS10225	COG4771	TonB-dependent receptor
C9E46_RS10240	COG4372	Transposase
C9E46_RS10245	COG3436	PFAM IS66 Orf2 family protein
C9E46_RS10260	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
C9E46_RS10275	COG1376	ErfK ybiS ycfS ynhG family protein
C9E46_RS10285	COG0583	DNA-binding transcription factor activity
C9E46_RS10290	COG0583	DNA-binding transcription factor activity
C9E46_RS10300	COG0534	Mate efflux family protein
C9E46_RS10310	COG0217	transcriptional regulatory protein
C9E46_RS10315	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C9E46_RS10320	COG0477	Major facilitator Superfamily
C9E46_RS10330	COG2373	Large extracellular alpha-helical protein
C9E46_RS10330	COG1388	LysM domain
C9E46_RS10330	COG4932	domain protein
C9E46_RS10360	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C9E46_RS10405	COG1846	Transcriptional regulator
C9E46_RS10455	COG1403	HNH endonuclease
C9E46_RS10460	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C9E46_RS10520	COG3772	lysozyme
C9E46_RS10555	COG4220	transposase activity
C9E46_RS10645	COG5301	cellulose 1,4-beta-cellobiosidase activity
C9E46_RS10670	COG3038	cytochrome b561
C9E46_RS10675	COG3443	Belongs to the bacterial solute-binding protein 9 family
C9E46_RS10690	COG2351	hydroxyisourate hydrolase activity
C9E46_RS10695	COG0745	RESPONSE REGULATOR receiver
C9E46_RS10700	COG2205	protein histidine kinase activity
C9E46_RS10725	COG1418	mRNA catabolic process
C9E46_RS10730	COG0270	DNA (cytosine-5-)-methyltransferase activity
C9E46_RS10735	COG3727	T/G mismatch-specific endonuclease activity
C9E46_RS10740	COG0697	spore germination
C9E46_RS10745	COG2354	Protein conserved in bacteria
C9E46_RS10750	COG5475	Uncharacterized small protein (DUF2158)
C9E46_RS10755	COG3706	GGDEF domain
C9E46_RS10780	COG2197	response regulator
C9E46_RS10785	COG1684	flagellar biosynthetic protein fliR
C9E46_RS10790	COG1987	bacterial-type flagellum assembly
C9E46_RS10795	COG1338	Plays a role in the flagellum-specific transport system
C9E46_RS10800	COG3190	flagellar
C9E46_RS10805	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C9E46_RS10810	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C9E46_RS10815	COG1580	Controls the rotational direction of flagella during chemotaxis
C9E46_RS10820	COG3144	bacterial-type flagellum assembly
C9E46_RS10825	COG2882	bacterial-type flagellum organization
C9E46_RS10830	COG1157	protein secretion by the type III secretion system
C9E46_RS10835	COG1317	bacterial-type flagellum organization
C9E46_RS10840	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C9E46_RS10845	COG1766	The M ring may be actively involved in energy transduction
C9E46_RS10865	COG0454	-acetyltransferase
C9E46_RS10880	COG0454	-acetyltransferase
C9E46_RS10885	COG2135	peptidase activity
C9E46_RS10890	COG0425	Belongs to the sulfur carrier protein TusA family
C9E46_RS10895	COG2391	methyltransferase activity
C9E46_RS10905	COG0366	Alpha amylase catalytic
C9E46_RS10915	COG1516	flagellar protein fliS
C9E46_RS10920	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C9E46_RS10930	COG1191	sigma factor activity
C9E46_RS10940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9E46_RS10950	COG0765	amino acid transport
C9E46_RS10955	COG1126	abc transporter atp-binding protein
C9E46_RS10960	COG2197	response regulator
C9E46_RS10980	COG2197	response regulator
C9E46_RS11020	COG2826	transposase and inactivated derivatives, IS30 family
C9E46_RS11170	COG4974	Belongs to the 'phage' integrase family
C9E46_RS11175	COG3012	SEC-C Motif Domain Protein
C9E46_RS11175	COG3318	Belongs to the UPF0149 family
C9E46_RS11180	COG0814	amino acid
C9E46_RS11190	COG1528	Iron-storage protein
C9E46_RS11210	COG1528	Iron-storage protein
C9E46_RS11215	COG1879	ABC-type sugar transport system periplasmic component
C9E46_RS11220	COG1129	ABC transporter
C9E46_RS11225	COG1172	Belongs to the binding-protein-dependent transport system permease family
C9E46_RS11230	COG1877	trehalose-phosphatase activity
C9E46_RS11240	COG0589	response to stress
C9E46_RS11255	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C9E46_RS11260	COG1360	Flagellar Motor Protein
C9E46_RS11265	COG0643	Histidine kinase
C9E46_RS11265	COG2198	Histidine kinase
C9E46_RS11270	COG0835	chemotaxis
C9E46_RS11275	COG0840	transmembrane signaling receptor activity
C9E46_RS11280	COG0840	transmembrane signaling receptor activity
C9E46_RS11285	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C9E46_RS11290	COG2201	protein-glutamate methylesterase activity
C9E46_RS11295	COG0745	RESPONSE REGULATOR receiver
C9E46_RS11305	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C9E46_RS11310	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C9E46_RS11320	COG3755	Protein conserved in bacteria
C9E46_RS11330	COG3102	Protein conserved in bacteria
C9E46_RS11340	COG3005	denitrification pathway
C9E46_RS11345	COG0243	molybdopterin cofactor binding
C9E46_RS11360	COG3788	relative of glutathione S-transferase, MAPEG superfamily
C9E46_RS11365	COG1801	Protein of unknown function DUF72
C9E46_RS11370	COG1335	isochorismatase
C9E46_RS11380	COG0494	nUDIX hydrolase
C9E46_RS11385	COG0217	transcriptional regulatory protein
C9E46_RS11415	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C9E46_RS11425	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
C9E46_RS11430	COG0739	heme binding
C9E46_RS11435	COG1560	Kdo2-lipid A biosynthetic process
C9E46_RS11440	COG0469	pyruvate kinase activity
C9E46_RS11445	COG1737	Transcriptional regulator
C9E46_RS11450	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C9E46_RS11455	COG0129	dihydroxy-acid dehydratase activity
C9E46_RS11460	COG0800	Aldolase
C9E46_RS11465	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
C9E46_RS11470	COG3141	response to X-ray
C9E46_RS11480	COG2979	Protein of unknown function (DUF533)
C9E46_RS11485	COG1770	oligopeptidase
C9E46_RS11490	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C9E46_RS11495	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C9E46_RS11505	COG2372	response to copper ion
C9E46_RS11510	COG1276	copper resistance
C9E46_RS11520	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C9E46_RS11540	COG3008	intermembrane lipid transfer
C9E46_RS11545	COG2995	paraquat-inducible protein a
C9E46_RS11550	COG1956	GAF domain-containing protein
C9E46_RS11560	COG0793	Belongs to the peptidase S41A family
C9E46_RS11570	COG2814	Major facilitator Superfamily
C9E46_RS11575	COG1414	Transcriptional regulator
C9E46_RS11605	COG2226	methyltransferase
C9E46_RS11620	COG3716	PTS system mannose fructose sorbose family IID component
C9E46_RS11625	COG3715	PTS system
C9E46_RS11630	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C9E46_RS11630	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9E46_RS11635	COG1253	flavin adenine dinucleotide binding
C9E46_RS11640	COG2200	EAL domain
C9E46_RS11645	COG1760	l-serine dehydratase
C9E46_RS11655	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C9E46_RS11670	COG0251	oxidation-reduction process
C9E46_RS11675	COG1199	ATP-dependent helicase activity
C9E46_RS11680	COG1214	PFAM Peptidase M22, glycoprotease
C9E46_RS11685	COG3065	identical protein binding
C9E46_RS11690	COG0318	PFAM AMP-dependent synthetase and ligase
C9E46_RS11695	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
C9E46_RS11700	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C9E46_RS11705	COG4638	Rieske (2fe-2S)
C9E46_RS11710	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C9E46_RS11715	COG0473	3-isopropylmalate dehydrogenase activity
C9E46_RS11720	COG0583	DNA-binding transcription factor activity
C9E46_RS11725	COG1280	lysine exporter protein (LysE YggA)
C9E46_RS11730	COG3615	Tellurite resistance protein tehB
C9E46_RS11740	COG2261	transglycosylase associated protein
C9E46_RS11755	COG2203	Gaf domain
C9E46_RS11755	COG2199	diguanylate cyclase activity
C9E46_RS11760	COG3042	response to heat
C9E46_RS11765	COG3189	MarR family transcriptional regulator
C9E46_RS11770	COG2807	transmembrane transport
C9E46_RS11775	COG2207	Transcriptional regulator
C9E46_RS11790	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C9E46_RS11795	COG2199	diguanylate cyclase activity
C9E46_RS11800	COG2199	diguanylate cyclase activity
C9E46_RS11810	COG2766	serine protein kinase
C9E46_RS11815	COG3713	MltA-interacting MipA family protein
C9E46_RS11820	COG0656	L-ascorbic acid biosynthetic process
C9E46_RS11825	COG0676	glucose-6-phosphate 1-epimerase activity
C9E46_RS11830	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C9E46_RS11840	COG3139	Protein of unknown function (DUF1315)
C9E46_RS11845	COG1063	alcohol dehydrogenase
C9E46_RS11850	COG2271	Major facilitator Superfamily
C9E46_RS11855	COG1063	alcohol dehydrogenase
C9E46_RS11860	COG0191	fructose-bisphosphate aldolase activity
C9E46_RS11865	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C9E46_RS11870	COG0667	Aldo Keto reductase
C9E46_RS11875	COG1349	DNA-binding transcription factor activity
C9E46_RS11890	COG2814	Major facilitator Superfamily
C9E46_RS11895	COG1335	isochorismatase
C9E46_RS11900	COG0252	asparaginase activity
C9E46_RS11910	COG0616	signal peptide processing
C9E46_RS11915	COG0778	Nitroreductase
C9E46_RS11920	COG0709	Synthesizes selenophosphate from selenide and ATP
C9E46_RS11925	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C9E46_RS11935	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C9E46_RS11945	COG0494	nUDIX hydrolase
C9E46_RS11950	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C9E46_RS11955	COG2897	thiosulfate sulfurtransferase activity
C9E46_RS11960	COG4136	ATPase activity
C9E46_RS11965	COG4135	transport system, permease component
C9E46_RS11970	COG4134	Bacterial extracellular solute-binding protein
C9E46_RS11975	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C9E46_RS11980	COG0398	Pfam SNARE associated Golgi protein
C9E46_RS11990	COG0398	Pfam SNARE associated Golgi protein
C9E46_RS11995	COG0708	Exodeoxyribonuclease III
C9E46_RS12025	COG3678	ATP-independent chaperone mediated protein folding
C9E46_RS12035	COG0322	excinuclease ABC activity
C9E46_RS12045	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C9E46_RS12055	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C9E46_RS12060	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C9E46_RS12065	COG1447	Phosphotransferase system cellobiose-specific component IIA
C9E46_RS12070	COG2169	Transcriptional regulator
C9E46_RS12070	COG1917	Cupin 2, conserved barrel domain protein
C9E46_RS12075	COG1486	melibiose metabolic process
C9E46_RS12085	COG0753	catalase activity
C9E46_RS12100	COG1823	symporter activity
C9E46_RS12105	COG1988	membrane-bound metal-dependent
C9E46_RS12110	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C9E46_RS12120	COG3001	Fructosamine kinase
C9E46_RS12130	COG1105	Belongs to the carbohydrate kinase PfkB family
C9E46_RS12135	COG3137	Salt-induced outer membrane protein
C9E46_RS12180	COG0072	phenylalanine-tRNA ligase activity
C9E46_RS12180	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C9E46_RS12195	COG0386	Belongs to the glutathione peroxidase family
C9E46_RS12205	COG0791	NLP P60 protein
C9E46_RS12210	COG2200	EAL domain
C9E46_RS12220	COG4256	Hemin uptake protein
C9E46_RS12225	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C9E46_RS12235	COG0574	Belongs to the PEP-utilizing enzyme family
C9E46_RS12235	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C9E46_RS12240	COG0318	PFAM AMP-dependent synthetase and ligase
C9E46_RS12245	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C9E46_RS12250	COG0644	oxidoreductase
C9E46_RS12255	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C9E46_RS12260	COG2086	electron transfer activity
C9E46_RS12265	COG1917	Cupin 2, conserved barrel domain protein
C9E46_RS12265	COG2207	Transcriptional regulator
C9E46_RS12270	COG1960	acyl-CoA dehydrogenase activity
C9E46_RS12275	COG4670	ketone body catabolic process
C9E46_RS12290	COG2271	Major facilitator Superfamily
C9E46_RS12295	COG0738	Major facilitator superfamily
C9E46_RS12310	COG0628	permease
C9E46_RS12315	COG0247	lactate metabolic process
C9E46_RS12315	COG0277	FAD linked oxidase domain protein
C9E46_RS12320	COG2050	protein possibly involved in aromatic compounds catabolism
C9E46_RS12330	COG0316	Belongs to the HesB IscA family
C9E46_RS12335	COG0719	Fe-S assembly protein
C9E46_RS12340	COG0396	ATPase activity
C9E46_RS12345	COG0719	Fe-S assembly protein
C9E46_RS12360	COG1376	ErfK ybiS ycfS ynhG family protein
C9E46_RS12365	COG4238	major outer membrane lipoprotein
C9E46_RS12370	COG0469	pyruvate kinase activity
C9E46_RS12380	COG0437	4 iron, 4 sulfur cluster binding
C9E46_RS12385	COG2414	aldehyde ferredoxin oxidoreductase
C9E46_RS12395	COG0437	4 iron, 4 sulfur cluster binding
C9E46_RS12400	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
C9E46_RS12410	COG4529	Protein conserved in bacteria
C9E46_RS12430	COG3468	outer membrane autotransporter barrel domain protein
C9E46_RS12440	COG0307	riboflavin synthase, alpha
C9E46_RS12445	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C9E46_RS12450	COG2814	Major facilitator Superfamily
C9E46_RS12455	COG0583	DNA-binding transcription factor activity
C9E46_RS12470	COG2814	Major facilitator Superfamily
C9E46_RS12475	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C9E46_RS12480	COG0791	NLP P60 protein
C9E46_RS12485	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C9E46_RS12490	COG1201	RNA secondary structure unwinding
C9E46_RS12500	COG0346	lactoylglutathione lyase activity
C9E46_RS12505	COG1902	pentaerythritol trinitrate reductase activity
C9E46_RS12510	COG1309	transcriptional regulator
C9E46_RS12515	COG3313	Fe-S protein
C9E46_RS12520	COG4989	oxidoreductase activity
C9E46_RS12525	COG2032	superoxide dismutase activity
C9E46_RS12530	COG1289	transmembrane transporter activity
C9E46_RS12535	COG1566	PFAM secretion protein HlyD family protein
C9E46_RS12550	COG3133	Outer membrane lipoprotein
C9E46_RS12560	COG3895	Periplasmic Protein
C9E46_RS12575	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
C9E46_RS12580	COG0625	glutathione transferase activity
C9E46_RS12585	COG3104	oligopeptide transport
C9E46_RS12590	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C9E46_RS12600	COG4659	FMN binding
C9E46_RS12640	COG0673	inositol 2-dehydrogenase activity
C9E46_RS12650	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C9E46_RS12655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C9E46_RS12655	COG1263	PTS System
C9E46_RS12660	COG1609	Transcriptional regulator
C9E46_RS12665	COG1028	Short-chain dehydrogenase reductase Sdr
C9E46_RS12670	COG1309	transcriptional regulator
C9E46_RS12690	COG5339	Protein conserved in bacteria
C9E46_RS12695	COG1482	cell wall glycoprotein biosynthetic process
C9E46_RS12700	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C9E46_RS12700	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C9E46_RS12705	COG0114	fumarate hydratase activity
C9E46_RS12715	COG2205	protein histidine kinase activity
C9E46_RS12720	COG0745	RESPONSE REGULATOR receiver
C9E46_RS12725	COG3136	membrane protein required for alginate biosynthesis
C9E46_RS12735	COG0531	amino acid
C9E46_RS12745	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
C9E46_RS12750	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
C9E46_RS12755	COG0628	permease
C9E46_RS12775	COG3591	Belongs to the peptidase S1B family
C9E46_RS12790	COG2814	Major facilitator Superfamily
C9E46_RS12795	COG0583	DNA-binding transcription factor activity
C9E46_RS12800	COG1940	carbohydrate kinase activity
C9E46_RS12805	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C9E46_RS12815	COG3381	protein complex oligomerization
C9E46_RS12820	COG3302	dmso reductase anchor subunit
C9E46_RS12825	COG0437	4 iron, 4 sulfur cluster binding
C9E46_RS12830	COG0243	molybdopterin cofactor binding
C9E46_RS12835	COG0243	molybdopterin cofactor binding
C9E46_RS12850	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C9E46_RS12880	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C9E46_RS12935	COG1846	Transcriptional regulator
C9E46_RS12940	COG1484	DNA-dependent DNA replication
C9E46_RS12975	COG1403	HNH endonuclease
C9E46_RS12980	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C9E46_RS13035	COG3772	lysozyme
C9E46_RS13175	COG5301	cellulose 1,4-beta-cellobiosidase activity
C9E46_RS13215	COG4372	Transposase
C9E46_RS13220	COG3436	PFAM IS66 Orf2 family protein
C9E46_RS13275	COG0582	viral genome integration into host DNA
C9E46_RS13295	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C9E46_RS13355	COG1846	Transcriptional regulator
C9E46_RS13390	COG3111	PFAM Bacterial OB fold (BOF) protein
C9E46_RS13400	COG1403	HNH endonuclease
C9E46_RS13405	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C9E46_RS13420	COG2207	Transcriptional regulator
C9E46_RS13460	COG3772	lysozyme
C9E46_RS13495	COG4220	transposase activity
C9E46_RS13515	COG1030	water channel activity
C9E46_RS13600	COG5301	cellulose 1,4-beta-cellobiosidase activity
C9E46_RS13635	COG0477	Major facilitator Superfamily
C9E46_RS13640	COG0246	Mannitol dehydrogenase
C9E46_RS13650	COG1802	Transcriptional regulator
C9E46_RS13655	COG4221	oxidoreductase activity
C9E46_RS13660	COG0339	signal peptide processing
C9E46_RS13665	COG1546	Belongs to the CinA family
C9E46_RS13670	COG3111	PFAM Bacterial OB fold (BOF) protein
C9E46_RS13675	COG3706	GGDEF domain
C9E46_RS13695	COG2814	Major facilitator Superfamily
C9E46_RS13700	COG0697	spore germination
C9E46_RS13710	COG4977	sequence-specific DNA binding
C9E46_RS13715	COG1846	Transcriptional regulator
C9E46_RS13720	COG2095	MarC family integral membrane protein
C9E46_RS13725	COG2814	Major facilitator Superfamily
C9E46_RS13735	COG0583	DNA-binding transcription factor activity
C9E46_RS13740	COG1012	belongs to the aldehyde dehydrogenase family
C9E46_RS13745	COG2066	Belongs to the glutaminase family
C9E46_RS13755	COG2199	diguanylate cyclase activity
C9E46_RS13775	COG1830	Aldolase
C9E46_RS13785	COG1172	Belongs to the binding-protein-dependent transport system permease family
C9E46_RS13790	COG1172	Belongs to the binding-protein-dependent transport system permease family
C9E46_RS13795	COG1129	ABC transporter
C9E46_RS13805	COG1070	Carbohydrate kinase
C9E46_RS13810	COG2911	Protein conserved in bacteria
C9E46_RS13810	COG3210	domain, Protein
C9E46_RS13835	COG3539	Fimbrial protein
C9E46_RS13845	COG3188	usher protein
C9E46_RS13850	COG3539	Fimbrial protein
C9E46_RS13855	COG3539	Fimbrial protein
C9E46_RS13860	COG3539	Fimbrial protein
C9E46_RS13865	COG0243	molybdopterin cofactor binding
C9E46_RS13875	COG2207	Transcriptional regulator
C9E46_RS13880	COG3119	arylsulfatase activity
C9E46_RS13885	COG0641	radical SAM
C9E46_RS13895	COG4178	(ABC) transporter
C9E46_RS13900	COG4771	TonB-dependent receptor
C9E46_RS13905	COG0612	Peptidase, M16
C9E46_RS13910	COG0076	glutamate decarboxylase activity
C9E46_RS13915	COG0531	amino acid
C9E46_RS13920	COG1649	PFAM Uncharacterised BCR, COG1649
C9E46_RS13925	COG3706	GGDEF domain
C9E46_RS13935	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
C9E46_RS13940	COG0747	negative chemotaxis
C9E46_RS13945	COG0601	transmembrane transport
C9E46_RS13950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C9E46_RS13955	COG0444	Belongs to the ABC transporter superfamily
C9E46_RS13960	COG4608	Belongs to the ABC transporter superfamily
C9E46_RS13965	COG1764	response to oxidative stress
C9E46_RS13985	COG1064	alcohol dehydrogenase
C9E46_RS13990	COG3093	addiction module antidote protein HigA
C9E46_RS13995	COG2864	formate dehydrogenase
C9E46_RS14000	COG0437	4 iron, 4 sulfur cluster binding
C9E46_RS14010	COG0697	spore germination
C9E46_RS14025	COG4886	Leucine-rich repeat (LRR) protein
C9E46_RS14030	COG4886	Leucine-rich repeat (LRR) protein
C9E46_RS14035	COG2223	nitrite transmembrane transporter activity
C9E46_RS14040	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C9E46_RS14045	COG1140	nitrate reductase beta subunit
C9E46_RS14050	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C9E46_RS14055	COG2181	nitrate reductase activity
C9E46_RS14060	COG0384	phenazine biosynthesis protein PhzF
C9E46_RS14070	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C9E46_RS14085	COG4372	Transposase
C9E46_RS14090	COG3436	PFAM IS66 Orf2 family protein
C9E46_RS14115	COG3209	COG3209 Rhs family protein
C9E46_RS14130	COG0625	glutathione transferase activity
C9E46_RS14135	COG1113	amino acid transport
C9E46_RS14140	COG3391	amine dehydrogenase activity
C9E46_RS14145	COG4772	TonB-dependent receptor
C9E46_RS14150	COG1802	Transcriptional regulator
C9E46_RS14155	COG2130	NADP-dependent
C9E46_RS14160	COG1247	-acetyltransferase
C9E46_RS14165	COG3238	Protein conserved in bacteria
C9E46_RS14190	COG1177	transmembrane transport
C9E46_RS14195	COG1176	ABC-type spermidine putrescine transport system, permease component I
C9E46_RS14200	COG3842	ATPase activity
C9E46_RS14205	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C9E46_RS14210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C9E46_RS14215	COG1598	PFAM Uncharacterised protein family UPF0150
C9E46_RS14220	COG1724	mRNA binding
C9E46_RS14230	COG0826	peptidase U32
C9E46_RS14235	COG1396	sequence-specific DNA binding
C9E46_RS14240	COG3135	benzoate transporter
C9E46_RS14250	COG0500	methyltransferase
C9E46_RS14255	COG1275	C4-dicarboxylate transporter malic acid transport protein
C9E46_RS14260	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C9E46_RS14270	COG2841	Protein conserved in bacteria
C9E46_RS14280	COG5383	Protein conserved in bacteria
C9E46_RS14285	COG0583	DNA-binding transcription factor activity
C9E46_RS14290	COG0840	transmembrane signaling receptor activity
C9E46_RS14305	COG3038	cytochrome b561
C9E46_RS14310	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C9E46_RS14315	COG1012	belongs to the aldehyde dehydrogenase family
C9E46_RS14320	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C9E46_RS14345	COG1643	Atp-dependent helicase
C9E46_RS14350	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C9E46_RS14355	COG0671	phosphoesterase, PA-phosphatase related
C9E46_RS14355	COG2453	phosphatase
C9E46_RS14360	COG2267	carboxylic ester hydrolase activity
C9E46_RS14365	COG4589	Belongs to the CDS family
C9E46_RS14370	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C9E46_RS14380	COG0667	Aldo Keto reductase
C9E46_RS14395	COG3784	Protein of unknown function (DUF1318)
C9E46_RS14405	COG2911	Protein conserved in bacteria
C9E46_RS14410	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C9E46_RS14415	COG3187	Heat shock protein
C9E46_RS14420	COG3042	response to heat
C9E46_RS14425	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
C9E46_RS14425	COG1013	pyruvate-flavodoxin oxidoreductase activity
C9E46_RS14425	COG0674	pyruvate-flavodoxin oxidoreductase activity
C9E46_RS14425	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C9E46_RS14435	COG0589	response to stress
C9E46_RS14445	COG0513	Belongs to the DEAD box helicase family
C9E46_RS14460	COG3706	GGDEF domain
C9E46_RS14465	COG2840	Smr protein MutS2
C9E46_RS14470	COG0583	DNA-binding transcription factor activity
C9E46_RS14475	COG1473	amidohydrolase
C9E46_RS14480	COG1473	amidohydrolase
C9E46_RS14485	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
C9E46_RS14490	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C9E46_RS14495	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C9E46_RS14500	COG0589	response to stress
C9E46_RS14505	COG3182	Iron-regulated membrane protein
C9E46_RS14510	COG0668	transmembrane transport
C9E46_RS14515	COG4166	transmembrane transport
C9E46_RS14520	COG0583	DNA-binding transcription factor activity
C9E46_RS14525	COG1073	alpha beta
C9E46_RS14530	COG1073	alpha beta
C9E46_RS14540	COG0702	epimerase
C9E46_RS14545	COG2866	Carboxypeptidase
C9E46_RS14550	COG4948	Mandelate Racemase Muconate Lactonizing
C9E46_RS14555	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
C9E46_RS14560	COG3283	Transcriptional regulator of aromatic amino acids metabolism
C9E46_RS14570	COG3106	COG3106 Predicted ATPase
C9E46_RS14575	COG1609	Transcriptional regulator
C9E46_RS14585	COG3842	ATPase activity
C9E46_RS14590	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C9E46_RS14595	COG1554	hydrolase, family 65, central catalytic
C9E46_RS14600	COG0673	inositol 2-dehydrogenase activity
C9E46_RS14605	COG1082	Xylose isomerase domain protein TIM barrel
C9E46_RS14610	COG1063	alcohol dehydrogenase
C9E46_RS14615	COG0395	ABC-type sugar transport system, permease component
C9E46_RS14620	COG1175	transmembrane transport
C9E46_RS14635	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C9E46_RS14645	COG1983	PspC domain protein
C9E46_RS14655	COG1842	Phage shock protein A
C9E46_RS14660	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C9E46_RS14665	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C9E46_RS14670	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C9E46_RS14675	COG1012	belongs to the aldehyde dehydrogenase family
C9E46_RS14680	COG1396	sequence-specific DNA binding
C9E46_RS14680	COG1917	Cupin 2, conserved barrel domain protein
C9E46_RS14685	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C9E46_RS14690	COG0174	glutamine synthetase
C9E46_RS14700	COG0531	amino acid
C9E46_RS14710	COG4166	transmembrane transport
C9E46_RS14715	COG4168	peptide transport system, permease
C9E46_RS14720	COG4171	peptide transport system, permease
C9E46_RS14725	COG4172	Belongs to the ABC transporter superfamily
C9E46_RS14730	COG4172	Belongs to the ABC transporter superfamily
C9E46_RS14735	COG2814	Major facilitator Superfamily
C9E46_RS14745	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C9E46_RS14750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C9E46_RS14760	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C9E46_RS14765	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C9E46_RS14765	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C9E46_RS14775	COG5001	Diguanylate cyclase
C9E46_RS14785	COG1349	DNA-binding transcription factor activity
C9E46_RS14795	COG0023	Translation Initiation Factor
C9E46_RS14805	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
C9E46_RS14810	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
C9E46_RS14815	COG0671	phosphoesterase, PA-phosphatase related
C9E46_RS14825	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C9E46_RS14845	COG0583	DNA-binding transcription factor activity
C9E46_RS14850	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C9E46_RS14860	COG0616	signal peptide processing
C9E46_RS14865	COG1028	Short-chain dehydrogenase reductase Sdr
C9E46_RS14870	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
C9E46_RS14875	COG1187	pseudouridine synthase activity
C9E46_RS14880	COG4907	membrane protein (DUF2207)
C9E46_RS14885	COG0009	L-threonylcarbamoyladenylate synthase
C9E46_RS14890	COG0613	PHP domain protein
C9E46_RS14900	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C9E46_RS14905	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C9E46_RS14905	COG0512	Glutamine amidotransferase of anthranilate synthase
C9E46_RS14910	COG0134	indole-3-glycerol-phosphate synthase activity
C9E46_RS14910	COG0135	phosphoribosylanthranilate isomerase activity
C9E46_RS14925	COG3729	General stress protein
C9E46_RS14930	COG3685	Protein conserved in bacteria
C9E46_RS14935	COG3685	Protein conserved in bacteria
C9E46_RS14975	COG5301	cellulose 1,4-beta-cellobiosidase activity
C9E46_RS15110	COG3772	lysozyme
C9E46_RS15160	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C9E46_RS15165	COG1403	HNH endonuclease
C9E46_RS15200	COG1846	Transcriptional regulator
C9E46_RS15230	COG1396	sequence-specific DNA binding
C9E46_RS15275	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C9E46_RS15285	COG0582	viral genome integration into host DNA
C9E46_RS15290	COG3047	cAMP biosynthetic process
C9E46_RS15310	COG1607	acyl-coa hydrolase
C9E46_RS15315	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
C9E46_RS15320	COG2350	Protein conserved in bacteria
C9E46_RS15325	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C9E46_RS15345	COG4608	Belongs to the ABC transporter superfamily
C9E46_RS15350	COG0444	Belongs to the ABC transporter superfamily
C9E46_RS15355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C9E46_RS15360	COG0601	transmembrane transport
C9E46_RS15365	COG4166	transmembrane transport
C9E46_RS15370	COG2095	MarC family integral membrane protein
C9E46_RS15375	COG1012	belongs to the aldehyde dehydrogenase family
C9E46_RS15375	COG1454	alcohol dehydrogenase
C9E46_RS15380	COG1435	thymidine kinase activity
C9E46_RS15390	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C9E46_RS15395	COG0745	RESPONSE REGULATOR receiver
C9E46_RS15400	COG1752	Esterase of the alpha-beta hydrolase superfamily
C9E46_RS15410	COG0788	formyltetrahydrofolate deformylase activity
C9E46_RS15440	COG2181	nitrate reductase activity
C9E46_RS15445	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C9E46_RS15450	COG1140	nitrate reductase beta subunit
C9E46_RS15455	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C9E46_RS15460	COG2223	nitrite transmembrane transporter activity
C9E46_RS15465	COG3850	Histidine kinase
C9E46_RS15470	COG2197	response regulator
C9E46_RS15475	COG4932	domain protein
C9E46_RS15480	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
C9E46_RS15485	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
C9E46_RS15490	COG4572	Cation transport regulator
C9E46_RS15495	COG0387	Pfam Sodium calcium exchanger
C9E46_RS15525	COG2912	Transglutaminase-like superfamily
C9E46_RS15530	COG3094	Invasion gene expression up-regulator, SirB
C9E46_RS15560	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C9E46_RS15565	COG0659	secondary active sulfate transmembrane transporter activity
C9E46_RS15580	COG0012	GTP binding
C9E46_RS15585	COG3468	outer membrane autotransporter barrel domain protein
C9E46_RS15590	COG3284	Transcriptional regulator
C9E46_RS15605	COG1619	proteins homologs of microcin C7 resistance protein MccF
C9E46_RS15625	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C9E46_RS15635	COG2719	SpoVR family
C9E46_RS15650	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C9E46_RS15655	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C9E46_RS15660	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C9E46_RS15675	COG0179	Fumarylacetoacetate (FAA) hydrolase
C9E46_RS15700	COG2894	cell division
C9E46_RS15725	COG4571	Outer membrane protease
C9E46_RS15740	COG4372	Transposase
C9E46_RS15745	COG3436	PFAM IS66 Orf2 family protein
C9E46_RS15760	COG0500	methyltransferase
C9E46_RS15770	COG3729	General stress protein
C9E46_RS15775	COG3685	Protein conserved in bacteria
C9E46_RS15780	COG3685	Protein conserved in bacteria
C9E46_RS15785	COG3546	catalase activity
C9E46_RS15790	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C9E46_RS15795	COG5301	cellulose 1,4-beta-cellobiosidase activity
C9E46_RS15830	COG1196	nuclear chromosome segregation
C9E46_RS15880	COG1030	water channel activity
C9E46_RS15900	COG4220	transposase activity
C9E46_RS15915	COG5562	phage envelope protein
C9E46_RS15955	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C9E46_RS15980	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C9E46_RS15990	COG2076	Multidrug Resistance protein
C9E46_RS16015	COG0582	viral genome integration into host DNA
C9E46_RS16020	COG0538	isocitrate dehydrogenase activity
C9E46_RS16025	COG1187	pseudouridine synthase activity
C9E46_RS16035	COG0482	sulfurtransferase activity
C9E46_RS16045	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C9E46_RS16050	COG0745	RESPONSE REGULATOR receiver
C9E46_RS16055	COG2205	protein histidine kinase activity
C9E46_RS16065	COG4220	transposase activity
C9E46_RS16175	COG2850	peptidyl-arginine hydroxylation
C9E46_RS16185	COG3842	ATPase activity
C9E46_RS16395	COG3772	lysozyme
C9E46_RS16435	COG0484	heat shock protein binding
C9E46_RS16440	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C9E46_RS16445	COG1403	HNH endonuclease
C9E46_RS16500	COG1846	Transcriptional regulator
C9E46_RS16520	COG4197	protein conserved in bacteria, prophage-related
C9E46_RS16550	COG0582	viral genome integration into host DNA
C9E46_RS16555	COG1177	transmembrane transport
C9E46_RS16560	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C9E46_RS16565	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C9E46_RS16575	COG4591	ABC-type transport system involved in lipoprotein release permease component
C9E46_RS16580	COG1136	(ABC) transporter
C9E46_RS16585	COG4591	ABC-type transport system involved in lipoprotein release permease component
C9E46_RS16590	COG4763	Acyl-transferase
C9E46_RS16595	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C9E46_RS16600	COG1376	ErfK ybiS ycfS ynhG family protein
C9E46_RS16600	COG1388	LysM domain
C9E46_RS16610	COG1309	transcriptional regulator
C9E46_RS16615	COG3134	Outer membrane lipoprotein
C9E46_RS16620	COG1252	NADH dehydrogenase
C9E46_RS16635	COG0510	thiamine kinase activity
C9E46_RS16640	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
C9E46_RS16645	COG5633	Lipoprotein
C9E46_RS16650	COG0537	adenosine 5'-monophosphoramidase activity
C9E46_RS16660	COG4773	Receptor
C9E46_RS16665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C9E46_RS16665	COG1263	PTS System
C9E46_RS16670	COG0084	hydrolase, TatD family'
C9E46_RS16675	COG0470	DNA polymerase III
C9E46_RS16685	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C9E46_RS16690	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C9E46_RS16695	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C9E46_RS16705	COG1028	Short-chain dehydrogenase reductase Sdr
C9E46_RS16710	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C9E46_RS16730	COG1399	metal-binding, possibly nucleic acid-binding protein
C9E46_RS16735	COG0424	maF-like protein
C9E46_RS16740	COG0564	pseudouridine synthase activity
C9E46_RS16745	COG1530	ribonuclease E activity
C9E46_RS16750	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C9E46_RS16755	COG1256	bacterial-type flagellum assembly
C9E46_RS16760	COG1705	Flagellar rod assembly protein muramidase FlgJ
C9E46_RS16760	COG3951	Flagellar rod assembly protein muramidase FlgJ
C9E46_RS16775	COG4786	Flagellar basal body rod
C9E46_RS16780	COG4787	bacterial-type flagellum-dependent cell motility
C9E46_RS16785	COG1749	Flagellar hook protein flgE
C9E46_RS16790	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C9E46_RS16795	COG1558	bacterial-type flagellum-dependent cell motility
C9E46_RS16800	COG1815	bacterial-type flagellum-dependent cell motility
C9E46_RS16805	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
C9E46_RS16810	COG2747	anti-sigma28 factor FlgM
C9E46_RS16815	COG3418	PFAM FlgN family protein
C9E46_RS16820	COG0728	peptidoglycan biosynthetic process
C9E46_RS16825	COG0673	inositol 2-dehydrogenase activity
C9E46_RS16835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C9E46_RS16845	COG2999	glutathione oxidoreductase activity
C9E46_RS16880	COG3038	cytochrome b561
C9E46_RS16885	COG2353	YceI-like domain
C9E46_RS16895	COG1560	Kdo2-lipid A biosynthetic process
C9E46_RS16910	COG5645	(Lipo)protein
C9E46_RS16915	COG2943	transferase activity, transferring hexosyl groups
C9E46_RS16930	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C9E46_RS16935	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C9E46_RS16960	COG2197	response regulator
C9E46_RS16975	COG1462	curli production assembly transport component CsgG
C9E46_RS16985	COG3381	protein complex oligomerization
C9E46_RS17035	COG2003	Belongs to the UPF0758 family
C9E46_RS17070	COG3468	outer membrane autotransporter barrel domain protein
C9E46_RS17185	COG4771	TonB-dependent receptor
C9E46_RS17250	COG1358	cellular component organization or biogenesis
C9E46_RS17285	COG4372	Transposase
C9E46_RS17290	COG3436	PFAM IS66 Orf2 family protein
C9E46_RS17335	COG0254	rRNA binding
C9E46_RS17380	COG0829	nickel cation binding
C9E46_RS17390	COG2194	sulfuric ester hydrolase activity
C9E46_RS17395	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C9E46_RS17455	COG3436	PFAM IS66 Orf2 family protein
C9E46_RS17460	COG4372	Transposase
C9E46_RS17485	COG4983	Phage plasmid primase, P4 family domain protein
C9E46_RS17515	COG0582	viral genome integration into host DNA
C9E46_RS17565	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C9E46_RS17570	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C9E46_RS17580	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C9E46_RS17590	COG0736	holo-[acyl-carrier-protein] synthase activity
C9E46_RS17595	COG2831	hemolysin activation secretion protein
C9E46_RS17600	COG3210	domain, Protein
C9E46_RS17610	COG3539	Fimbrial protein
C9E46_RS17620	COG3188	usher protein
C9E46_RS17630	COG3121	Chaperone
C9E46_RS17635	COG1028	Short-chain dehydrogenase reductase Sdr
C9E46_RS17640	COG3710	Transcriptional regulator
C9E46_RS17650	COG2200	EAL domain
C9E46_RS17655	COG3706	GGDEF domain
C9E46_RS17660	COG0457	Tetratricopeptide repeat
C9E46_RS17665	COG1649	PFAM Uncharacterised BCR, COG1649
C9E46_RS17665	COG0726	polysaccharide deacetylase
C9E46_RS17670	COG1215	transferase activity, transferring glycosyl groups
C9E46_RS17675	COG3658	cytochrome
C9E46_RS17680	COG1702	phosphate starvation-inducible protein PhoH
C9E46_RS17685	COG2837	iron assimilation
C9E46_RS17690	COG2822	iron ion transport
C9E46_RS17705	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C9E46_RS17715	COG0506	proline dehydrogenase activity
C9E46_RS17715	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C9E46_RS17715	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C9E46_RS17720	COG1309	transcriptional regulator
C9E46_RS17760	COG2233	PERMEase
C9E46_RS17765	COG3729	General stress protein
C9E46_RS17805	COG0243	molybdopterin cofactor binding
C9E46_RS17810	COG3005	denitrification pathway
C9E46_RS17815	COG0745	RESPONSE REGULATOR receiver
C9E46_RS17820	COG1879	ABC-type sugar transport system periplasmic component
C9E46_RS17825	COG2205	protein histidine kinase activity
C9E46_RS17825	COG2198	Histidine kinase
C9E46_RS17825	COG0784	Response regulator, receiver
C9E46_RS17830	COG0348	domain, Protein
C9E46_RS17850	COG1278	Cold shock
C9E46_RS17855	COG1278	Cold shock
C9E46_RS17875	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C9E46_RS17880	COG1596	polysaccharide export
C9E46_RS17885	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C9E46_RS17890	COG0489	protein tyrosine kinase activity
C9E46_RS17890	COG3206	protein involved in exopolysaccharide biosynthesis
C9E46_RS17905	COG1294	oxidase, subunit
C9E46_RS17910	COG1271	oxidase subunit
C9E46_RS17915	COG1773	rubredoxin
C9E46_RS17920	COG1999	signal sequence binding
C9E46_RS17925	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C9E46_RS17930	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
C9E46_RS17935	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
C9E46_RS17940	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
C9E46_RS17965	COG5301	cellulose 1,4-beta-cellobiosidase activity
C9E46_RS17980	COG2032	superoxide dismutase activity
C9E46_RS18060	COG4220	transposase activity
C9E46_RS18065	COG4372	Transposase
C9E46_RS18070	COG3436	PFAM IS66 Orf2 family protein
C9E46_RS18105	COG3772	lysozyme
C9E46_RS18165	COG2207	Transcriptional regulator
C9E46_RS18185	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C9E46_RS18190	COG1403	HNH endonuclease
C9E46_RS18230	COG1846	Transcriptional regulator
C9E46_RS18235	COG1484	DNA-dependent DNA replication
C9E46_RS18310	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C9E46_RS18325	COG0670	Belongs to the BI1 family
C9E46_RS18330	COG2920	part of a sulfur-relay system
C9E46_RS18335	COG1254	Belongs to the acylphosphatase family
C9E46_RS18350	COG1832	CoA-binding protein
C9E46_RS18365	COG0210	DNA helicase
C9E46_RS18370	COG3304	Inner membrane component domain
C9E46_RS18375	COG1289	transmembrane transporter activity
C9E46_RS18380	COG3070	regulator of competence-specific genes
C9E46_RS18390	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
C9E46_RS18390	COG2885	chlorophyll binding
C9E46_RS18400	COG1067	ATP-dependent peptidase activity
C9E46_RS18410	COG3130	regulation of translation
C9E46_RS18415	COG3009	Protein conserved in bacteria
C9E46_RS18420	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C9E46_RS18420	COG3008	intermembrane lipid transfer
C9E46_RS18425	COG2995	paraquat-inducible protein a
C9E46_RS18430	COG0488	(ABC) transporter
C9E46_RS18440	COG0633	Ferredoxin
C9E46_RS18440	COG3217	Mosc domain protein beta barrel domain protein
C9E46_RS18460	COG3539	Fimbrial protein
C9E46_RS18465	COG3539	Fimbrial protein
C9E46_RS18470	COG3539	Fimbrial protein
C9E46_RS18480	COG3121	Chaperone
C9E46_RS18485	COG3539	Fimbrial protein
C9E46_RS18490	COG0431	NADPH-dependent FMN reductase
C9E46_RS18495	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C9E46_RS18505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C9E46_RS18510	COG1116	anion transmembrane transporter activity
C9E46_RS18515	COG0308	aminopeptidase N
C9E46_RS18525	COG0017	Asparaginyl-tRNA synthetase
C9E46_RS18535	COG1448	Aminotransferase
C9E46_RS18540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C9E46_RS18545	COG3108	Peptidase M15
C9E46_RS18550	COG2989	Protein conserved in bacteria
C9E46_RS18560	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
C9E46_RS18570	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C9E46_RS18575	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C9E46_RS18580	COG3173	Aminoglycoside phosphotransferase
C9E46_RS18595	COG3214	Protein conserved in bacteria
C9E46_RS18605	COG1132	(ABC) transporter
C9E46_RS18610	COG2333	competence protein COMEC
C9E46_RS18610	COG0658	competence protein
C9E46_RS18620	COG0539	negative regulation of cytoplasmic translation
C9E46_RS18630	COG0501	Belongs to the peptidase M48B family
C9E46_RS18645	COG2323	membrane
C9E46_RS18650	COG1944	ATP diphosphatase activity
C9E46_RS18655	COG2116	formate transmembrane transporter activity
C9E46_RS18660	COG1882	Formate acetyltransferase
C9E46_RS18665	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C9E46_RS18675	COG0531	amino acid
C9E46_RS18685	COG1335	isochorismatase
C9E46_RS18690	COG3302	dmso reductase anchor subunit
C9E46_RS18695	COG0437	4 iron, 4 sulfur cluster binding
C9E46_RS18700	COG0243	molybdopterin cofactor binding
C9E46_RS18710	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C9E46_RS18720	COG1178	ABC-type Fe3 transport system permease component
C9E46_RS18720	COG1674	ftsk spoiiie
C9E46_RS18725	COG1522	sequence-specific DNA binding
C9E46_RS18730	COG0492	ferredoxin-NADP+ reductase activity
C9E46_RS18735	COG4988	ABC transporter
C9E46_RS18740	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C9E46_RS18760	COG0542	response to heat
C9E46_RS18770	COG1278	Cold shock
C9E46_RS18775	COG0577	efflux transmembrane transporter activity
C9E46_RS18775	COG1136	(ABC) transporter
C9E46_RS18780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C9E46_RS18785	COG2990	Protein conserved in bacteria
C9E46_RS18790	COG3593	DNA synthesis involved in DNA repair
C9E46_RS18805	COG2431	L-lysine efflux transmembrane transporter activity
C9E46_RS18815	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C9E46_RS18820	COG0028	Belongs to the TPP enzyme family
C9E46_RS18825	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
C9E46_RS18830	COG0702	epimerase
C9E46_RS18835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C9E46_RS18840	COG3023	N-Acetylmuramoyl-L-alanine amidase
C9E46_RS18870	COG1126	abc transporter atp-binding protein
C9E46_RS18875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9E46_RS18880	COG4215	(ABC) transporter
C9E46_RS18885	COG4160	amino acid transport
C9E46_RS18890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9E46_RS18920	COG1177	transmembrane transport
C9E46_RS18925	COG1176	ABC-type spermidine putrescine transport system, permease component I
C9E46_RS18930	COG3842	ATPase activity
C9E46_RS18935	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C9E46_RS18950	COG0778	Nitroreductase
C9E46_RS18960	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C9E46_RS18975	COG3226	Transcriptional regulator
C9E46_RS18980	COG0738	Major facilitator superfamily
C9E46_RS18985	COG0561	phosphatase activity
C9E46_RS18995	COG2814	Major facilitator Superfamily
C9E46_RS19000	COG0671	phosphoesterase, PA-phosphatase related
C9E46_RS19005	COG1349	DNA-binding transcription factor activity
C9E46_RS19010	COG1686	Belongs to the peptidase S11 family
C9E46_RS19015	COG0625	glutathione transferase activity
C9E46_RS19020	COG2133	pyrroloquinoline quinone binding
C9E46_RS19045	COG2199	diguanylate cyclase activity
C9E46_RS19050	COG2200	EAL domain
C9E46_RS19060	COG0601	transmembrane transport
C9E46_RS19065	COG0747	negative chemotaxis
C9E46_RS19070	COG4172	Belongs to the ABC transporter superfamily
C9E46_RS19080	COG0303	'Molybdopterin
C9E46_RS19085	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C9E46_RS19090	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C9E46_RS19095	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C9E46_RS19105	COG0561	phosphatase activity
C9E46_RS19115	COG0488	(ABC) transporter
C9E46_RS19120	COG1376	ErfK ybiS ycfS ynhG family protein
C9E46_RS19125	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C9E46_RS19130	COG1321	iron dependent repressor
C9E46_RS19140	COG2194	sulfuric ester hydrolase activity
C9E46_RS19145	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
C9E46_RS19155	COG5006	permease, DMT superfamily
C9E46_RS19165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9E46_RS19170	COG0765	amino acid transport
C9E46_RS19175	COG1126	abc transporter atp-binding protein
C9E46_RS19180	COG0668	transmembrane transport
C9E46_RS19195	COG4774	siderophore transport
C9E46_RS19205	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C9E46_RS19215	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
C9E46_RS19220	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C9E46_RS19225	COG1199	ATP-dependent helicase activity
C9E46_RS19235	COG0513	Belongs to the DEAD box helicase family
C9E46_RS19240	COG1309	transcriptional regulator
C9E46_RS19250	COG1131	(ABC) transporter
C9E46_RS19255	COG0842	Transport permease protein
C9E46_RS19260	COG0842	Transport permease protein
C9E46_RS19270	COG3568	Endonuclease Exonuclease Phosphatase
C9E46_RS19275	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C9E46_RS19280	COG0392	lysyltransferase activity
C9E46_RS19285	COG0670	Belongs to the BI1 family
C9E46_RS19290	COG0670	Belongs to the BI1 family
C9E46_RS19295	COG0314	molybdopterin synthase activity
C9E46_RS19300	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C9E46_RS19310	COG0521	Mo-molybdopterin cofactor biosynthetic process
C9E46_RS19320	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C9E46_RS19330	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C9E46_RS19335	COG2226	methyltransferase
C9E46_RS19350	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C9E46_RS19355	COG1881	PFAM PEBP family protein
C9E46_RS19400	COG5301	cellulose 1,4-beta-cellobiosidase activity
C9E46_RS19475	COG0740	serine-type endopeptidase activity
C9E46_RS19520	COG3772	lysozyme
C9E46_RS19565	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C9E46_RS19635	COG0582	viral genome integration into host DNA
C9E46_RS19640	COG4677	pectinesterase activity
C9E46_RS19645	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C9E46_RS19650	COG0471	metal ion transport
C9E46_RS19655	COG2828	Protein conserved in bacteria
C9E46_RS19660	COG0583	DNA-binding transcription factor activity
C9E46_RS19670	COG0561	phosphatase activity
C9E46_RS19680	COG4149	molybdate abc transporter
C9E46_RS19685	COG0725	ABC transporter, periplasmic molybdate-binding protein
C9E46_RS19695	COG3585	molybdate ion transport
C9E46_RS19695	COG2005	Transcriptional regulator
C9E46_RS19700	COG1119	ATPase activity
C9E46_RS19705	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C9E46_RS19710	COG1085	galactose-1-phosphate uridylyltransferase
C9E46_RS19720	COG2017	converts alpha-aldose to the beta-anomer
C9E46_RS19730	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C9E46_RS19740	COG1230	cation diffusion facilitator family transporter
C9E46_RS19745	COG3201	nicotinamide mononucleotide transporter
C9E46_RS19750	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
C9E46_RS19785	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
C9E46_RS19790	COG2885	chlorophyll binding
C9E46_RS19800	COG3064	Membrane
C9E46_RS19805	COG0848	biopolymer transport protein
C9E46_RS19810	COG0811	peptide transport
C9E46_RS19815	COG0824	Thioesterase
C9E46_RS19820	COG3790	cyd operon protein YbgE
C9E46_RS19825	COG4890	Cyd operon protein YbgT
C9E46_RS19830	COG1294	oxidase, subunit
C9E46_RS19835	COG1271	oxidase subunit
C9E46_RS19850	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C9E46_RS19860	COG4865	methylaspartate mutase activity
C9E46_RS19865	COG3799	methylaspartate ammonia-lyase activity
C9E46_RS19880	COG1301	dicarboxylic acid transport
C9E46_RS19885	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C9E46_RS19885	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C9E46_RS19890	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
C9E46_RS19895	COG0583	DNA-binding transcription factor activity
C9E46_RS19910	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C9E46_RS19920	COG0508	dehydrogenase complex catalyzes the overall conversion of
C9E46_RS19925	COG0567	Dehydrogenase, E1 component
C9E46_RS19930	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C9E46_RS19935	COG1053	succinate dehydrogenase
C9E46_RS19940	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
C9E46_RS19945	COG2009	succinate dehydrogenase
C9E46_RS19955	COG0372	Belongs to the citrate synthase family
C9E46_RS19960	COG3539	Fimbrial protein
C9E46_RS19965	COG3188	usher protein
C9E46_RS19970	COG3121	Chaperone
C9E46_RS19975	COG3539	Fimbrial protein
C9E46_RS19980	COG3180	Ammonia monooxygenase
C9E46_RS19985	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C9E46_RS19995	COG1984	allophanate hydrolase subunit 2
C9E46_RS20000	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C9E46_RS20005	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C9E46_RS20010	COG3104	oligopeptide transport
C9E46_RS20015	COG0415	Belongs to the DNA photolyase family
C9E46_RS20020	COG3272	Protein of unknown function (DUF1722)
C9E46_RS20025	COG5433	transposase activity
C9E46_RS20050	COG3209	COG3209 Rhs family protein
C9E46_RS20080	COG2205	protein histidine kinase activity
C9E46_RS20085	COG0745	RESPONSE REGULATOR receiver
C9E46_RS20100	COG1982	Orn Lys Arg decarboxylase major
C9E46_RS20105	COG0531	amino acid
C9E46_RS20110	COG0033	Phosphoglucomutase
C9E46_RS20115	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
C9E46_RS20120	COG0596	Alpha beta hydrolase
C9E46_RS20130	COG0716	FMN binding
C9E46_RS20140	COG0735	belongs to the Fur family
C9E46_RS20165	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C9E46_RS20165	COG1263	PTS System
C9E46_RS20165	COG2190	(PTS) system
C9E46_RS20175	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C9E46_RS20180	COG1846	Transcriptional regulator
C9E46_RS20180	COG1940	carbohydrate kinase activity
C9E46_RS20185	COG0647	UMP catabolic process
C9E46_RS20190	COG0367	asparagine synthase
C9E46_RS20230	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C9E46_RS20240	COG1702	phosphate starvation-inducible protein PhoH
C9E46_RS20250	COG4535	Mg2 and Co2 transporter CorC
C9E46_RS20255	COG0815	Transfers the fatty acyl group on membrane lipoproteins
C9E46_RS20260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9E46_RS20265	COG0765	amino acid transport
C9E46_RS20270	COG0765	amino acid transport
C9E46_RS20275	COG1126	abc transporter atp-binding protein
C9E46_RS20285	COG0443	Heat shock 70 kDa protein
C9E46_RS20300	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C9E46_RS20305	COG2214	Heat shock protein DnaJ domain protein
C9E46_RS20320	COG2888	peptidyl-tyrosine sulfation
C9E46_RS20335	COG1466	dna polymerase III delta subunit
C9E46_RS20345	COG0406	alpha-ribazole phosphatase activity
C9E46_RS20350	COG0799	negative regulation of ribosome biogenesis
C9E46_RS20360	COG0768	penicillin binding
C9E46_RS20365	COG0772	Belongs to the SEDS family
C9E46_RS20370	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C9E46_RS20375	COG1686	Belongs to the peptidase S11 family
C9E46_RS20390	COG0583	DNA-binding transcription factor activity
C9E46_RS20400	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C9E46_RS20405	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C9E46_RS20425	COG3069	C4-dicarboxylate transmembrane transporter activity
C9E46_RS20430	COG4565	transcriptional regulatory protein
C9E46_RS20435	COG3290	protein histidine kinase activity
C9E46_RS20440	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
C9E46_RS20450	COG2301	Belongs to the HpcH HpaI aldolase family
C9E46_RS20455	COG3051	citrate lyase alpha subunit
C9E46_RS20465	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
C9E46_RS20470	COG0471	metal ion transport
C9E46_RS20475	COG3719	Belongs to the RNase T2 family
C9E46_RS20480	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C9E46_RS20485	COG1063	alcohol dehydrogenase
C9E46_RS20490	COG0589	response to stress
C9E46_RS20495	COG3634	alkyl hydroperoxide reductase activity
C9E46_RS20500	COG0450	alkyl hydroperoxide reductase
C9E46_RS20505	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C9E46_RS20510	COG0583	DNA-binding transcription factor activity
C9E46_RS20515	COG3969	phosphoadenosine phosphosulfate
C9E46_RS20520	COG1475	DNA binding
C9E46_RS20525	COG0436	Aminotransferase
C9E46_RS20530	COG0371	Dehydrogenase
C9E46_RS20535	COG2879	small protein
C9E46_RS20540	COG1966	Carbon starvation protein
C9E46_RS20550	COG1028	Short-chain dehydrogenase reductase Sdr
C9E46_RS20555	COG3433	isochorismatase activity
C9E46_RS20555	COG1535	isochorismatase
C9E46_RS20560	COG1021	2,3-dihydroxybenzoate-AMP ligase
C9E46_RS20565	COG1169	isochorismate synthase
C9E46_RS20570	COG4592	Periplasmic binding protein
C9E46_RS20580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C9E46_RS20585	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C9E46_RS20590	COG1120	ATPase activity
C9E46_RS20595	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
C9E46_RS20600	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9E46_RS20600	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
C9E46_RS20605	COG3251	PFAM MbtH domain protein
C9E46_RS20610	COG2382	esterase
C9E46_RS20615	COG4771	TonB-dependent receptor
C9E46_RS20620	COG2977	Belongs to the P-Pant transferase superfamily
C9E46_RS20655	COG2315	Protein conserved in bacteria
C9E46_RS20660	COG0778	Nitroreductase
C9E46_RS20665	COG0668	transmembrane transport
C9E46_RS20670	COG1113	amino acid transport
C9E46_RS20675	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C9E46_RS20680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C9E46_RS20685	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C9E46_RS20690	COG1538	Outer membrane efflux protein
C9E46_RS20695	COG0745	RESPONSE REGULATOR receiver
C9E46_RS20700	COG5002	protein histidine kinase activity
C9E46_RS20715	COG3209	COG3209 Rhs family protein
C9E46_RS20715	COG4104	PAAR repeat-containing protein
C9E46_RS20730	COG4104	PAAR repeat-containing protein
C9E46_RS20730	COG3209	COG3209 Rhs family protein
C9E46_RS20740	COG5433	transposase activity
C9E46_RS20745	COG1215	transferase activity, transferring glycosyl groups
C9E46_RS20760	COG2207	Transcriptional regulator
C9E46_RS20770	COG2197	response regulator
C9E46_RS20775	COG3539	Fimbrial protein
C9E46_RS20780	COG3539	Fimbrial protein
C9E46_RS20785	COG3188	usher protein
C9E46_RS20790	COG3121	Chaperone
C9E46_RS20795	COG3539	Fimbrial protein
C9E46_RS20805	COG2501	S4 domain
C9E46_RS20810	COG1988	membrane-bound metal-dependent
C9E46_RS20820	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C9E46_RS20830	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C9E46_RS20835	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C9E46_RS20840	COG0549	Belongs to the carbamate kinase family
C9E46_RS20850	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C9E46_RS20855	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C9E46_RS20860	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
C9E46_RS20865	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C9E46_RS20870	COG3257	ureidoglycine aminohydrolase activity
C9E46_RS20875	COG1929	Belongs to the glycerate kinase type-1 family
C9E46_RS20880	COG2233	PERMEase
C9E46_RS20890	COG1953	Uracil, thiamine, allantoin
C9E46_RS20895	COG2084	Dehydrogenase
C9E46_RS20900	COG3622	Belongs to the hyi family
C9E46_RS20905	COG3960	tartronate-semialdehyde synthase activity
C9E46_RS20910	COG1414	Transcriptional regulator
C9E46_RS20920	COG0583	DNA-binding transcription factor activity
C9E46_RS20940	COG3209	COG3209 Rhs family protein
C9E46_RS20945	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
C9E46_RS20950	COG4181	ATPase activity
C9E46_RS20955	COG2755	lipolytic protein G-D-S-L family
C9E46_RS20960	COG0300	oxidoreductase activity
C9E46_RS20965	COG3118	belongs to the thioredoxin family
C9E46_RS20970	COG0390	transport system, permease component
C9E46_RS20975	COG4619	ABC transporter
C9E46_RS20980	COG0330	HflC and HflK could
C9E46_RS20985	COG1585	Membrane protein implicated in regulation of membrane protease activity
C9E46_RS21010	COG0789	Transcriptional regulator
C9E46_RS21035	COG0531	amino acid
C9E46_RS21040	COG2066	Belongs to the glutaminase family
C9E46_RS21045	COG2217	Heavy metal translocating P-type atpase
C9E46_RS21050	COG3093	addiction module antidote protein HigA
C9E46_RS21060	COG3735	TraB family
C9E46_RS21065	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C9E46_RS21070	COG0737	Belongs to the 5'-nucleotidase family
C9E46_RS21075	COG2223	nitrite transmembrane transporter activity
C9E46_RS21080	COG4651	solute:proton antiporter activity
C9E46_RS21080	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C9E46_RS21085	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C9E46_RS21120	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C9E46_RS21130	COG2832	Protein of unknown function (DUF454)
C9E46_RS21135	COG3923	Primosomal replication protein n
C9E46_RS21145	COG3264	Mechanosensitive ion channel
C9E46_RS21145	COG1196	nuclear chromosome segregation
C9E46_RS21150	COG1309	transcriptional regulator
C9E46_RS21155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C9E46_RS21160	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C9E46_RS21175	COG0110	maltose O-acetyltransferase activity
C9E46_RS21185	COG4943	cyclic-guanylate-specific phosphodiesterase activity
C9E46_RS21190	COG5507	3-demethylubiquinone-9 3-methyltransferase
C9E46_RS21200	COG3695	enzyme binding
C9E46_RS21205	COG3126	Type III secretion system lipoprotein chaperone (YscW)
C9E46_RS21210	COG1946	Acyl-CoA thioesterase
C9E46_RS21215	COG0004	ammonium transporteR
C9E46_RS21220	COG0347	Belongs to the P(II) protein family
C9E46_RS21225	COG1132	(ABC) transporter
C9E46_RS21230	COG1132	(ABC) transporter
C9E46_RS21235	COG1522	sequence-specific DNA binding
C9E46_RS21245	COG4533	DNA binding
C9E46_RS21255	COG0824	Thioesterase
C9E46_RS21260	COG1555	photosystem II stabilization
C9E46_RS21265	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C9E46_RS21270	COG0776	regulation of translation
C9E46_RS21275	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C9E46_RS21295	COG0271	Belongs to the BolA IbaG family
C9E46_RS21300	COG3056	Lipoprotein
C9E46_RS21305	COG2223	nitrite transmembrane transporter activity
C9E46_RS21310	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C9E46_RS21315	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C9E46_RS21320	COG1845	cytochrome c oxidase, subunit III
C9E46_RS21325	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C9E46_RS21335	COG2814	Major facilitator Superfamily
C9E46_RS21345	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C9E46_RS21350	COG0693	protein deglycase activity
C9E46_RS21365	COG0142	geranyltranstransferase activity
C9E46_RS21375	COG0667	Aldo Keto reductase
C9E46_RS21385	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C9E46_RS21390	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C9E46_RS21405	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C9E46_RS21405	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C9E46_RS21415	COG4238	major outer membrane lipoprotein
C9E46_RS21420	COG3248	Nucleoside-binding outer membrane protein
C9E46_RS21425	COG1403	HNH endonuclease
C9E46_RS21435	COG3609	addiction module antidote protein, CC2985 family
C9E46_RS21440	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C9E46_RS21445	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C9E46_RS21450	COG1862	Preprotein translocase
C9E46_RS21475	COG0366	Alpha amylase catalytic
C9E46_RS21480	COG1113	amino acid transport
C9E46_RS21485	COG1114	Component of the transport system for branched-chain amino acids
C9E46_RS21490	COG5002	protein histidine kinase activity
C9E46_RS21495	COG0745	RESPONSE REGULATOR receiver
C9E46_RS21500	COG0420	3'-5' exonuclease activity
C9E46_RS21505	COG0419	ATPase involved in DNA repair
C9E46_RS21510	COG2814	Major facilitator Superfamily
C9E46_RS21515	COG1940	carbohydrate kinase activity
C9E46_RS21540	COG4126	flavin adenine dinucleotide binding
C9E46_RS21560	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C9E46_RS21565	COG3706	GGDEF domain
C9E46_RS21575	COG1785	Belongs to the alkaline phosphatase family
C9E46_RS21585	COG1181	Belongs to the D-alanine--D-alanine ligase family
C9E46_RS21605	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
C9E46_RS21610	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C9E46_RS21615	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C9E46_RS21620	COG3468	outer membrane autotransporter barrel domain protein
C9E46_RS21625	COG0113	porphobilinogen synthase activity
C9E46_RS21630	COG2175	clavaminate synthase activity
C9E46_RS21635	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C9E46_RS21640	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
C9E46_RS21645	COG4521	taurine ABC transporter
C9E46_RS21660	COG2271	Major facilitator Superfamily
C9E46_RS21665	COG1840	ABC-type Fe3 transport system, periplasmic component
C9E46_RS21675	COG3842	ATPase activity
C9E46_RS21690	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
C9E46_RS21695	COG3122	Protein conserved in bacteria
C9E46_RS21700	COG2814	Major facilitator Superfamily
C9E46_RS21705	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C9E46_RS21720	COG0596	Alpha beta hydrolase
C9E46_RS21735	COG1414	Transcriptional regulator
C9E46_RS21740	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
C9E46_RS21750	COG1609	Transcriptional regulator
C9E46_RS21755	COG3250	beta-galactosidase activity
C9E46_RS21760	COG2223	nitrite transmembrane transporter activity
C9E46_RS21765	COG0110	maltose O-acetyltransferase activity
C9E46_RS21770	COG2807	transmembrane transport
C9E46_RS21780	COG0288	reversible hydration of carbon dioxide
C9E46_RS21785	COG0583	DNA-binding transcription factor activity
C9E46_RS21790	COG0402	S-adenosylhomocysteine deaminase activity
C9E46_RS21795	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C9E46_RS21800	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C9E46_RS21805	COG2079	MmgE PrpD family protein
C9E46_RS21810	COG0372	Belongs to the citrate synthase family
C9E46_RS21815	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C9E46_RS21820	COG3829	transcription factor binding
C9E46_RS21830	COG1280	lysine exporter protein (LysE YggA)
C9E46_RS21845	COG1064	alcohol dehydrogenase
C9E46_RS21855	COG1172	Belongs to the binding-protein-dependent transport system permease family
C9E46_RS21860	COG1129	ABC transporter
C9E46_RS21865	COG1879	ABC-type sugar transport system periplasmic component
C9E46_RS21875	COG0402	S-adenosylhomocysteine deaminase activity
C9E46_RS21880	COG0549	Belongs to the carbamate kinase family
C9E46_RS21890	COG1304	FMN binding
C9E46_RS21895	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C9E46_RS21905	COG0666	response to abiotic stimulus
C9E46_RS21920	COG2771	luxR family
C9E46_RS21920	COG2200	EAL domain
C9E46_RS21930	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C9E46_RS21960	COG2771	luxR family
C9E46_RS21960	COG2200	EAL domain
C9E46_RS21990	COG1556	Lactate utilization protein
C9E46_RS21995	COG1139	Iron-sulfur cluster binding protein
C9E46_RS22000	COG0247	lactate metabolic process
C9E46_RS22005	COG2207	Transcriptional regulator
C9E46_RS22010	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C9E46_RS22020	COG3059	membrane
C9E46_RS22025	COG0656	L-ascorbic acid biosynthetic process
C9E46_RS22030	COG3708	Transcriptional regulator
C9E46_RS22030	COG2207	Transcriptional regulator
C9E46_RS22035	COG1388	LysM domain
C9E46_RS22050	COG0583	DNA-binding transcription factor activity
C9E46_RS22055	COG1073	alpha beta
C9E46_RS22060	COG1902	pentaerythritol trinitrate reductase activity
C9E46_RS22070	COG4372	Transposase
C9E46_RS22075	COG3436	PFAM IS66 Orf2 family protein
C9E46_RS22120	COG3188	usher protein
C9E46_RS22130	COG3121	Chaperone
C9E46_RS22135	COG0727	PFAM Uncharacterised protein family (UPF0153)
C9E46_RS22140	COG3477	response to acidic pH
C9E46_RS22145	COG2080	2 iron, 2 sulfur cluster binding
C9E46_RS22150	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C9E46_RS22155	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C9E46_RS22160	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C9E46_RS22175	COG0583	DNA-binding transcription factor activity
C9E46_RS22190	COG4221	oxidoreductase activity
C9E46_RS22195	COG0583	DNA-binding transcription factor activity
C9E46_RS22280	COG0582	viral genome integration into host DNA
C9E46_RS22300	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C9E46_RS22315	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C9E46_RS22325	COG3778	Protein conserved in bacteria
C9E46_RS22330	COG3299	homolog of phage Mu protein gp47
C9E46_RS22350	COG4228	DNA circulation
C9E46_RS22375	COG4386	tail sheath protein
C9E46_RS22420	COG4626	Terminase
C9E46_RS22420	COG1802	Transcriptional regulator
C9E46_RS22475	COG0484	heat shock protein binding
C9E46_RS22480	COG1403	HNH endonuclease
C9E46_RS22490	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C9E46_RS22500	COG4725	Belongs to the MT-A70-like family
C9E46_RS22510	COG1846	Transcriptional regulator
C9E46_RS22560	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
C9E46_RS22580	COG0582	viral genome integration into host DNA
C9E46_RS22600	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C9E46_RS22620	COG2195	Cleaves the N-terminal amino acid of tripeptides
C9E46_RS22625	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
C9E46_RS22630	COG1690	Belongs to the RtcB family
C9E46_RS22635	COG0454	-acetyltransferase
C9E46_RS22645	COG2161	toxin-antitoxin pair type II binding
C9E46_RS22650	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C9E46_RS22670	COG0791	NLP P60 protein
C9E46_RS22675	COG3077	Addiction module antitoxin, RelB DinJ family
C9E46_RS22680	COG3041	Addiction module toxin RelE StbE family
C9E46_RS22685	COG3034	peptidoglycan biosynthetic process
C9E46_RS22690	COG0121	glutamine amidotransferase
C9E46_RS22700	COG1960	acyl-CoA dehydrogenase activity
C9E46_RS22710	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C9E46_RS22715	COG5433	transposase activity
C9E46_RS22730	COG3209	COG3209 Rhs family protein
C9E46_RS22855	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C9E46_RS22865	COG2226	methyltransferase
C9E46_RS22875	COG0741	lytic transglycosylase activity
C9E46_RS22875	COG1388	LysM domain
C9E46_RS22880	COG2226	methyltransferase
C9E46_RS22890	COG0583	DNA-binding transcription factor activity
C9E46_RS22895	COG0656	L-ascorbic acid biosynthetic process
C9E46_RS22930	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C9E46_RS22935	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C9E46_RS22940	COG2011	ABC-type metal ion transport system permease component
C9E46_RS22945	COG1464	Belongs to the NlpA lipoprotein family
C9E46_RS22955	COG1720	tRNA m6t6A37 methyltransferase activity
C9E46_RS22965	COG0791	NLP P60 protein
C9E46_RS22970	COG3015	lipoprotein NlpE involved in copper resistance
C9E46_RS22975	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
C9E46_RS22980	COG4681	YaeQ
C9E46_RS22990	COG4568	rho-dependent transcription termination
C9E46_RS22995	COG0037	tRNA processing
C9E46_RS23000	COG0346	lactoylglutathione lyase activity
C9E46_RS23005	COG1982	Orn Lys Arg decarboxylase major
C9E46_RS23015	COG0587	DNA-directed DNA polymerase activity
C9E46_RS23040	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C9E46_RS23045	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
C9E46_RS23055	COG0750	zinc metalloprotease
C9E46_RS23060	COG0575	Belongs to the CDS family
C9E46_RS23065	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C9E46_RS23070	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C9E46_RS23095	COG0024	Methionine aminopeptidase
C9E46_RS23115	COG3835	regulator
C9E46_RS23120	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C9E46_RS23135	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C9E46_RS23140	COG2860	membrane
C9E46_RS23165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C9E46_RS23170	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C9E46_RS23175	COG1120	ATPase activity
C9E46_RS23180	COG4774	siderophore transport
C9E46_RS23185	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C9E46_RS23190	COG1643	Atp-dependent helicase
C9E46_RS23195	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C9E46_RS23205	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C9E46_RS23210	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C9E46_RS23215	COG0617	tRNA 3'-terminal CCA addition
C9E46_RS23220	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C9E46_RS23240	COG2842	Transposition protein
C9E46_RS23270	COG4396	Host-nuclease inhibitor protein Gam
C9E46_RS23325	COG5566	PFAM Mor transcription activator
C9E46_RS23365	COG4373	Mu-like prophage FluMu protein gp28
C9E46_RS23370	COG4383	Mu-like prophage protein gp29
C9E46_RS23375	COG2369	cell adhesion
C9E46_RS23380	COG5005	Phage virion morphogenesis
C9E46_RS23385	COG4388	Caudovirus prohead serine protease
C9E46_RS23390	COG4397	Mu-like prophage major head subunit gpT
C9E46_RS23415	COG4386	tail sheath protein
C9E46_RS23425	COG4518	Phage tail assembly chaperone proteins, E, or 41 or 14
C9E46_RS23450	COG4384	Bacteriophage Mu Gp45 protein
C9E46_RS23460	COG3299	homolog of phage Mu protein gp47
C9E46_RS23490	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C9E46_RS23535	COG3121	Chaperone
C9E46_RS23540	COG3188	usher protein
C9E46_RS23545	COG3539	Fimbrial protein
C9E46_RS23550	COG3539	Fimbrial protein
C9E46_RS23575	COG5464	transposase or invertase
C9E46_RS23585	COG0726	polysaccharide deacetylase
C9E46_RS23590	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9E46_RS23595	COG0842	Transport permease protein
C9E46_RS23600	COG1131	(ABC) transporter
C9E46_RS23605	COG0288	reversible hydration of carbon dioxide
C9E46_RS23610	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
C9E46_RS23615	COG4993	Dehydrogenase
C9E46_RS23620	COG2132	Multicopper oxidase
C9E46_RS23645	COG1049	propionate catabolic process, 2-methylcitrate cycle
C9E46_RS23650	COG3064	Membrane
C9E46_RS23655	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C9E46_RS23660	COG0508	dehydrogenase complex catalyzes the overall conversion of
C9E46_RS23665	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
C9E46_RS23670	COG2186	Transcriptional regulator
C9E46_RS23675	COG1113	amino acid transport
C9E46_RS23680	COG3725	Membrane protein required for beta-lactamase induction
C9E46_RS23685	COG3023	N-Acetylmuramoyl-L-alanine amidase
C9E46_RS23690	COG0157	Belongs to the NadC ModD family
C9E46_RS23695	COG4969	Belongs to the N-Me-Phe pilin family
C9E46_RS23700	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C9E46_RS23705	COG1459	type II secretion system
C9E46_RS23715	COG0237	dephospho-CoA kinase activity
C9E46_RS23730	COG0494	nUDIX hydrolase
C9E46_RS23750	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C9E46_RS23755	COG0849	cell division
C9E46_RS23760	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C9E46_RS23765	COG1181	Belongs to the D-alanine--D-alanine ligase family
C9E46_RS23780	COG0772	Belongs to the SEDS family
C9E46_RS23785	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C9E46_RS23795	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C9E46_RS23800	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C9E46_RS23805	COG0768	penicillin binding
C9E46_RS23810	COG3116	cell division
C9E46_RS23825	COG1609	Transcriptional regulator
C9E46_RS23835	COG0440	acetolactate synthase activity
C9E46_RS23840	COG0028	Belongs to the TPP enzyme family
C9E46_RS23845	COG0583	DNA-binding transcription factor activity
C9E46_RS23860	COG0473	3-isopropylmalate dehydrogenase activity
C9E46_RS23880	COG4533	DNA binding
C9E46_RS23890	COG4143	(ABC) transporter
C9E46_RS23895	COG1178	ABC-type Fe3 transport system permease component
C9E46_RS23900	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
C9E46_RS23905	COG0586	Pfam SNARE associated Golgi protein
C9E46_RS23910	COG4977	sequence-specific DNA binding
C9E46_RS23925	COG0235	Class ii aldolase
C9E46_RS23930	COG0417	DNA replication proofreading
C9E46_RS23940	COG0564	pseudouridine synthase activity
C9E46_RS23950	COG1357	PFAM Pentapeptide repeats (8 copies)
C9E46_RS23955	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
C9E46_RS23960	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
C9E46_RS23965	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C9E46_RS24000	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C9E46_RS24015	COG2271	Major facilitator Superfamily
C9E46_RS24020	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C9E46_RS24025	COG0644	oxidoreductase
C9E46_RS24075	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C9E46_RS24080	COG0505	Belongs to the CarA family
C9E46_RS24100	COG1047	Peptidyl-prolyl cis-trans
C9E46_RS24115	COG0196	riboflavin kinase activity
C9E46_RS24140	COG3121	Chaperone
C9E46_RS24145	COG3188	usher protein
C9E46_RS24155	COG0583	DNA-binding transcription factor activity
C9E46_RS24185	COG4735	regulation of single-species biofilm formation
C9E46_RS24190	COG1584	GPR1 FUN34 yaaH family protein
C9E46_RS24195	COG0521	Mo-molybdopterin cofactor biosynthetic process
C9E46_RS24200	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C9E46_RS24205	COG1115	amino acid carrier protein
C9E46_RS24220	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C9E46_RS24230	COG0527	aspartate kinase activity
C9E46_RS24230	COG0460	homoserine dehydrogenase
C9E46_RS24240	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
C9E46_RS24250	COG0745	RESPONSE REGULATOR receiver
C9E46_RS24255	COG4452	Inner membrane protein CreD
C9E46_RS24260	COG2205	protein histidine kinase activity
C9E46_RS24265	COG0745	RESPONSE REGULATOR receiver
C9E46_RS24270	COG3045	CreA protein
C9E46_RS24275	COG2207	Transcriptional regulator
C9E46_RS24275	COG3708	Transcriptional regulator
C9E46_RS24285	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
C9E46_RS24295	COG0741	lytic transglycosylase activity
C9E46_RS24300	COG0488	(ABC) transporter
C9E46_RS24305	COG1056	cytidyltransferase-related domain
C9E46_RS24305	COG3172	ATPase kinase involved in NAD metabolism
C9E46_RS24310	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C9E46_RS24315	COG0560	Phosphoserine phosphatase
C9E46_RS24325	COG0095	Lipoate-protein ligase
C9E46_RS24325	COG3726	membrane protein affecting hemolysin expression
C9E46_RS24360	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C9E46_RS24365	COG0084	hydrolase, TatD family'
C9E46_RS24370	COG4667	esterase of the alpha-beta hydrolase superfamily
C9E46_RS24380	COG2823	Periplasmic or secreted lipoprotein
C9E46_RS24390	COG1011	Hydrolase
C9E46_RS24395	COG0456	acetyltransferase
C9E46_RS24400	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
C9E46_RS24420	COG4114	ferric iron reductase
C9E46_RS24425	COG2197	response regulator
C9E46_RS24430	COG2197	response regulator
C9E46_RS24435	COG2966	Psort location CytoplasmicMembrane, score
C9E46_RS24450	COG1484	DNA-dependent DNA replication
C9E46_RS24465	COG1063	alcohol dehydrogenase
C9E46_RS24470	COG1802	Transcriptional regulator
C9E46_RS24475	COG2271	Major facilitator Superfamily
C9E46_RS24480	COG0840	transmembrane signaling receptor activity
C9E46_RS24490	COG1966	Carbon starvation protein
C9E46_RS24495	COG2879	small protein
C9E46_RS24500	COG0523	cobalamin synthesis protein
C9E46_RS24525	COG0732	type I restriction modification DNA specificity domain
C9E46_RS24545	COG5457	Domain of unknown function (DUF1127)
C9E46_RS24550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C9E46_RS24560	COG2814	Major facilitator Superfamily
C9E46_RS24565	COG2733	membrane
C9E46_RS24570	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
C9E46_RS24575	COG1924	4 iron, 4 sulfur cluster binding
C9E46_RS24595	COG3204	pilus organization
C9E46_RS24600	COG0477	Major facilitator Superfamily
C9E46_RS24605	COG4932	domain protein
C9E46_RS24605	COG1388	LysM domain
C9E46_RS24605	COG2373	Large extracellular alpha-helical protein
C9E46_RS24610	COG1388	LysM domain
C9E46_RS24610	COG1470	cell adhesion involved in biofilm formation
C9E46_RS24620	COG3366	ferrous iron transmembrane transporter activity
C9E46_RS24625	COG0700	Nucleoside recognition
C9E46_RS24630	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C9E46_RS24655	COG2186	Transcriptional regulator
C9E46_RS24660	COG0246	Mannitol dehydrogenase
C9E46_RS24670	COG2610	gluconate transmembrane transporter activity
C9E46_RS24675	COG3539	Fimbrial protein
C9E46_RS24680	COG3539	Fimbrial protein
C9E46_RS24685	COG3539	Fimbrial protein
C9E46_RS24690	COG3188	usher protein
C9E46_RS24695	COG3121	Chaperone
C9E46_RS24700	COG3539	Fimbrial protein
C9E46_RS24705	COG3539	Fimbrial protein
C9E46_RS24710	COG4974	Belongs to the 'phage' integrase family
C9E46_RS24715	COG0582	viral genome integration into host DNA
C9E46_RS24720	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
C9E46_RS24725	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
C9E46_RS24740	COG0210	DNA helicase
C9E46_RS24745	COG1111	helicase
C9E46_RS24745	COG1205	dead DEAH box helicase
C9E46_RS24755	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C9E46_RS24800	COG0582	viral genome integration into host DNA
C9E46_RS24885	COG0582	viral genome integration into host DNA
C9E46_RS24895	COG1064	alcohol dehydrogenase
C9E46_RS24900	COG0433	COG0433 Predicted ATPase
C9E46_RS24905	COG0795	lipopolysaccharide-transporting ATPase activity
C9E46_RS24910	COG0795	lipopolysaccharide-transporting ATPase activity
C9E46_RS24920	COG2927	DNA polymerase III (CHI subunit)
C9E46_RS24930	COG4269	membrane
C9E46_RS24935	COG0456	acetyltransferase
C9E46_RS24940	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
C9E46_RS24945	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C9E46_RS24955	COG2731	YhcH YjgK YiaL family protein
C9E46_RS24960	COG1309	transcriptional regulator
C9E46_RS24965	COG1028	Short-chain dehydrogenase reductase Sdr
C9E46_RS24970	COG0251	oxidation-reduction process
C9E46_RS24990	COG0251	oxidation-reduction process
C9E46_RS24995	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C9E46_RS25005	COG1609	Transcriptional regulator
C9E46_RS25010	COG1263	PTS System
C9E46_RS25010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C9E46_RS25015	COG0366	Alpha amylase catalytic
C9E46_RS25020	COG1328	CTP reductase activity
C9E46_RS25025	COG0602	queuosine metabolic process
C9E46_RS25030	COG3783	Cytochrome b(562)
C9E46_RS25035	COG0312	modulator of DNA gyrase
C9E46_RS25045	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C9E46_RS25055	COG1172	Belongs to the binding-protein-dependent transport system permease family
C9E46_RS25060	COG1172	Belongs to the binding-protein-dependent transport system permease family
C9E46_RS25065	COG1129	ABC transporter
C9E46_RS25070	COG1879	ABC-type sugar transport system periplasmic component
C9E46_RS25075	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
C9E46_RS25080	COG2337	Toxic component of a toxin-antitoxin (TA) module
C9E46_RS25085	COG2336	PFAM SpoVT AbrB
C9E46_RS25090	COG2105	PFAM AIG2 family protein
C9E46_RS25095	COG2911	Protein conserved in bacteria
C9E46_RS25100	COG0729	surface antigen
C9E46_RS25110	COG1253	flavin adenine dinucleotide binding
C9E46_RS25120	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
C9E46_RS25130	COG1218	3'(2'),5'-bisphosphate nucleotidase
C9E46_RS25135	COG0737	Belongs to the 5'-nucleotidase family
C9E46_RS25140	COG1733	regulation of RNA biosynthetic process
C9E46_RS25145	COG0702	epimerase
C9E46_RS25150	COG0697	spore germination
C9E46_RS25160	COG1113	amino acid transport
C9E46_RS25165	COG0545	Peptidyl-prolyl cis-trans isomerase
C9E46_RS25170	COG3061	Opacity-associated protein A
C9E46_RS25180	COG0675	Transposase, IS605 OrfB family
C9E46_RS25205	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C9E46_RS25240	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9E46_RS25245	COG3414	Phosphotransferase system galactitol-specific IIB component
C9E46_RS25250	COG3037	sugar-specific permease SgaT UlaA
C9E46_RS25265	COG1073	alpha beta
C9E46_RS25270	COG3650	response to hydrogen peroxide
C9E46_RS25280	COG1960	acyl-CoA dehydrogenase activity
C9E46_RS25285	COG0754	glutathionylspermidine amidase activity
C9E46_RS25290	COG5463	Belongs to the UPF0441 family
C9E46_RS25295	COG3766	membrane
C9E46_RS25305	COG1842	Phage shock protein A
C9E46_RS25310	COG3789	protein conserved in bacteria
C9E46_RS25315	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C9E46_RS25320	COG0557	exoribonuclease II activity
C9E46_RS25335	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
C9E46_RS25340	COG0330	HflC and HflK could
C9E46_RS25345	COG0330	HflC and HflK could
C9E46_RS25350	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C9E46_RS25370	COG0860	N-Acetylmuramoyl-L-alanine amidase
C9E46_RS25375	COG0802	atpase or kinase
C9E46_RS25380	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C9E46_RS25380	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C9E46_RS25410	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
C9E46_RS25425	COG1511	domain protein
C9E46_RS25425	COG3264	Mechanosensitive ion channel
C9E46_RS25430	COG0531	amino acid
C9E46_RS25440	COG1053	succinate dehydrogenase
C9E46_RS25445	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C9E46_RS25460	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C9E46_RS25465	COG3040	lipid binding
C9E46_RS25470	COG2076	Multidrug Resistance protein
C9E46_RS25475	COG5510	response to toxic substance
C9E46_RS25480	COG5510	response to toxic substance
C9E46_RS25490	COG1509	lysine 2,3-aminomutase activity
C9E46_RS25515	COG0531	amino acid
C9E46_RS25520	COG3030	protein affecting phage T7 exclusion by the F plasmid
C9E46_RS25525	COG1027	Aspartate ammonia-lyase
C9E46_RS25530	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C9E46_RS25540	COG4232	protein-disulfide reductase activity
C9E46_RS25545	COG1309	transcriptional regulator
C9E46_RS25555	COG3710	Transcriptional regulator
C9E46_RS25565	COG0531	amino acid
C9E46_RS25570	COG1982	Orn Lys Arg decarboxylase major
C9E46_RS25575	COG3104	oligopeptide transport
C9E46_RS25580	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C9E46_RS25595	COG2388	GCN5-related N-acetyl-transferase
C9E46_RS25600	COG3592	Divergent 4Fe-4S mono-cluster
C9E46_RS25605	COG3290	protein histidine kinase activity
C9E46_RS25610	COG4565	transcriptional regulatory protein
C9E46_RS25620	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C9E46_RS25625	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C9E46_RS25625	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C9E46_RS25630	COG3647	Membrane
C9E46_RS25640	COG2211	Major facilitator Superfamily
C9E46_RS25645	COG1486	melibiose metabolic process
C9E46_RS25650	COG2169	Transcriptional regulator
C9E46_RS25655	COG1982	Orn Lys Arg decarboxylase major
C9E46_RS25660	COG2207	Transcriptional regulator
C9E46_RS25665	COG0531	amino acid
C9E46_RS25670	COG2194	sulfuric ester hydrolase activity
C9E46_RS25675	COG0745	RESPONSE REGULATOR receiver
C9E46_RS25680	COG0642	Histidine kinase
C9E46_RS25690	COG0477	Major facilitator Superfamily
C9E46_RS25700	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C9E46_RS25705	COG2824	Alkylphosphonate utilization operon protein PhnA
C9E46_RS25710	COG2764	glyoxalase bleomycin resistance protein dioxygenase
C9E46_RS25715	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
C9E46_RS25720	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
C9E46_RS25725	COG3639	organic phosphonate transmembrane transporter activity
C9E46_RS25730	COG2188	Transcriptional regulator
C9E46_RS25735	COG3624	Phosphonate C-P lyase system protein PhnG
C9E46_RS25740	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
C9E46_RS25745	COG3626	phosphonate metabolism
C9E46_RS25750	COG3627	carbon phosphorus lyase activity
C9E46_RS25755	COG4107	phosphonate C-P lyase system protein PhnK
C9E46_RS25760	COG4778	phosphonate C-P lyase system protein PhnL
C9E46_RS25765	COG3454	Phosphonate metabolism
C9E46_RS25770	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
C9E46_RS25775	COG0456	acetyltransferase
C9E46_RS25780	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C9E46_RS25800	COG1129	ABC transporter
C9E46_RS25805	COG1172	Belongs to the binding-protein-dependent transport system permease family
C9E46_RS25825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C9E46_RS25835	COG2015	COG2015, Alkyl sulfatase and related hydrolases
C9E46_RS25845	COG1566	PFAM secretion protein HlyD family protein
C9E46_RS25850	COG1289	transmembrane transporter activity
C9E46_RS25855	COG1538	Outer membrane efflux protein
C9E46_RS25865	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C9E46_RS25870	COG1301	dicarboxylic acid transport
C9E46_RS25875	COG4235	cytochrome complex assembly
C9E46_RS25880	COG3088	subunit of a heme lyase
C9E46_RS25885	COG1138	Cytochrome C-type biogenesis protein
C9E46_RS25890	COG3301	Polysulphide reductase, NrfD
C9E46_RS25895	COG0437	4 iron, 4 sulfur cluster binding
C9E46_RS25900	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
C9E46_RS25910	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C9E46_RS25915	COG3162	membrane
C9E46_RS25925	COG1357	PFAM Pentapeptide repeats (8 copies)
C9E46_RS25930	COG0025	NhaP-type Na H and K H
C9E46_RS25935	COG2252	PERMEase
C9E46_RS25940	COG0789	Transcriptional regulator
C9E46_RS25945	COG2207	Transcriptional regulator
C9E46_RS25950	COG4943	cyclic-guanylate-specific phosphodiesterase activity
C9E46_RS25960	COG0629	single-stranded DNA binding
C9E46_RS25965	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C9E46_RS25970	COG2315	Protein conserved in bacteria
C9E46_RS25975	COG0432	Pfam Uncharacterised protein family UPF0047
C9E46_RS25980	COG3700	Belongs to the class B bacterial acid phosphatase family
C9E46_RS25990	COG1448	Aminotransferase
C9E46_RS25995	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C9E46_RS26000	COG0305	Participates in initiation and elongation during chromosome replication
C9E46_RS26005	COG0604	alcohol dehydrogenase
C9E46_RS26015	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C9E46_RS26060	COG5301	cellulose 1,4-beta-cellobiosidase activity
C9E46_RS26080	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
C9E46_RS26120	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C9E46_RS26130	COG0735	belongs to the Fur family
C9E46_RS26135	COG3237	CsbD-like
C9E46_RS26140	COG0534	Mate efflux family protein
C9E46_RS26150	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C9E46_RS26170	COG1357	PFAM Pentapeptide repeats (8 copies)
C9E46_RS26185	COG3842	ATPase activity
C9E46_RS26195	COG2182	Extracellular solute-binding protein
C9E46_RS26200	COG1175	transmembrane transport
C9E46_RS26205	COG3833	ABC-type maltose transport systems, permease component
C9E46_RS26210	COG0477	Major facilitator Superfamily
C9E46_RS26210	COG2814	Major facilitator Superfamily
C9E46_RS26225	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C9E46_RS26250	COG0527	aspartate kinase activity
C9E46_RS26260	COG1187	pseudouridine synthase activity
C9E46_RS26305	COG1283	sodium-dependent phosphate transmembrane transporter activity
C9E46_RS26310	COG1410	methionine synthase
C9E46_RS26310	COG0646	methionine synthase
C9E46_RS26315	COG1414	Transcriptional regulator
C9E46_RS26330	COG2224	Isocitrate lyase
C9E46_RS26335	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C9E46_RS26345	COG0456	acetyltransferase
C9E46_RS26375	COG0151	Belongs to the GarS family
C9E46_RS26380	COG2204	response regulator
C9E46_RS26385	COG4191	Histidine kinase
C9E46_RS26390	COG3678	ATP-independent chaperone mediated protein folding
C9E46_RS26405	COG3068	Protein conserved in bacteria
C9E46_RS26440	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C9E46_RS26445	COG2104	thiamine diphosphate biosynthetic process
C9E46_RS26450	COG2022	thiamine diphosphate biosynthetic process
C9E46_RS26455	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
C9E46_RS26495	COG0250	Participates in transcription elongation, termination and antitermination
C9E46_RS26500	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C9E46_RS26535	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
C9E46_RS26535	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
C9E46_RS26540	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C9E46_RS26565	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C9E46_RS26570	COG4206	TonB-dependent receptor
C9E46_RS26575	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C9E46_RS26585	COG1309	transcriptional regulator
C9E46_RS26590	COG0477	Major facilitator Superfamily
C9E46_RS26595	COG1473	amidohydrolase
C9E46_RS26605	COG0583	DNA-binding transcription factor activity
C9E46_RS26620	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C9E46_RS26635	COG2194	sulfuric ester hydrolase activity
C9E46_RS26640	COG2207	Transcriptional regulator
C9E46_RS26645	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C9E46_RS26650	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C9E46_RS26655	COG1882	Formate acetyltransferase
C9E46_RS26660	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C9E46_RS26665	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C9E46_RS26670	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C9E46_RS26670	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9E46_RS26670	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9E46_RS26675	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C9E46_RS26680	COG0371	Dehydrogenase
C9E46_RS26685	COG3738	Protein conserved in bacteria
C9E46_RS26690	COG0697	spore germination
C9E46_RS26700	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C9E46_RS26705	COG0527	aspartate kinase activity
C9E46_RS26705	COG0460	homoserine dehydrogenase
C9E46_RS26710	COG0626	cystathionine gamma-synthase activity
C9E46_RS26720	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
C9E46_RS26735	COG3209	COG3209 Rhs family protein
C9E46_RS26745	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C9E46_RS26750	COG1609	Transcriptional regulator
C9E46_RS26755	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C9E46_RS26770	COG1575	Belongs to the MenA family. Type 1 subfamily
C9E46_RS26795	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C9E46_RS26805	COG1494	fructose-1,6-bisphosphatase
C9E46_RS26815	COG0589	response to stress
C9E46_RS26820	COG3691	Protein conserved in bacteria
C9E46_RS26825	COG3152	Membrane
C9E46_RS26845	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C9E46_RS26860	COG3678	ATP-independent chaperone mediated protein folding
C9E46_RS26865	COG0745	RESPONSE REGULATOR receiver
C9E46_RS26870	COG2205	protein histidine kinase activity
C9E46_RS26875	COG2258	MOSC domain
C9E46_RS26885	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C9E46_RS26895	COG1917	Cupin 2, conserved barrel domain protein
C9E46_RS26895	COG4977	sequence-specific DNA binding
C9E46_RS26930	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9E46_RS26935	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C9E46_RS26935	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C9E46_RS26940	COG1363	Peptidase, m42
C9E46_RS26945	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9E46_RS26945	COG3711	transcriptional antiterminator
C9E46_RS26965	COG0437	4 iron, 4 sulfur cluster binding
C9E46_RS26970	COG2864	formate dehydrogenase
C9E46_RS26980	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C9E46_RS26985	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C9E46_RS27010	COG0456	acetyltransferase
C9E46_RS27025	COG1011	Hydrolase
C9E46_RS27030	COG1349	DNA-binding transcription factor activity
C9E46_RS27035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C9E46_RS27040	COG2084	Dehydrogenase
C9E46_RS27045	COG3684	Belongs to the aldolase LacD family
C9E46_RS27050	COG2942	2-epimerase
C9E46_RS27055	COG2017	converts alpha-aldose to the beta-anomer
C9E46_RS27065	COG1501	Belongs to the glycosyl hydrolase 31 family
C9E46_RS27070	COG2211	Major facilitator Superfamily
C9E46_RS27075	COG2211	Major facilitator Superfamily
C9E46_RS27080	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
C9E46_RS27085	COG2271	Major facilitator Superfamily
C9E46_RS27090	COG1082	Xylose isomerase domain protein TIM barrel
C9E46_RS27095	COG2188	Transcriptional regulator
C9E46_RS27100	COG1217	gtp-binding protein TYPA
C9E46_RS27105	COG0174	glutamine synthetase
C9E46_RS27110	COG3852	Histidine kinase
C9E46_RS27115	COG2204	response regulator
C9E46_RS27125	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C9E46_RS27130	COG3078	GTPase activator activity
C9E46_RS27140	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C9E46_RS27140	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C9E46_RS27150	COG0204	Acyl-transferase
C9E46_RS27155	COG5339	Protein conserved in bacteria
C9E46_RS27160	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C9E46_RS27165	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C9E46_RS27170	COG3084	Protein conserved in bacteria
C9E46_RS27175	COG0746	molybdenum cofactor guanylyltransferase activity
C9E46_RS27180	COG1763	Mo-molybdopterin cofactor biosynthetic process
C9E46_RS27210	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
C9E46_RS27215	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C9E46_RS27220	COG1739	Uncharacterized protein family UPF0029
C9E46_RS27235	COG0183	Belongs to the thiolase family
C9E46_RS27240	COG0543	2 iron, 2 sulfur cluster binding
C9E46_RS27245	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C9E46_RS27250	COG0250	Participates in transcription elongation, termination and antitermination
C9E46_RS27255	COG0084	hydrolase, TatD family'
C9E46_RS27260	COG0805	protein transport
C9E46_RS27265	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C9E46_RS27270	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C9E46_RS27280	COG3165	ubiquinone biosynthetic process from chorismate
C9E46_RS27290	COG1322	Protein conserved in bacteria
C9E46_RS27295	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
C9E46_RS27300	COG0412	Dienelactone hydrolase
C9E46_RS27310	COG0583	DNA-binding transcription factor activity
C9E46_RS27315	COG0697	spore germination
C9E46_RS27320	COG0561	phosphatase activity
C9E46_RS27325	COG2267	carboxylic ester hydrolase activity
C9E46_RS27330	COG1280	lysine exporter protein (LysE YggA)
C9E46_RS27335	COG1280	lysine exporter protein (LysE YggA)
C9E46_RS27340	COG0514	ATP-dependent DNA helicase (RecQ)
C9E46_RS27345	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
C9E46_RS27350	COG2050	protein possibly involved in aromatic compounds catabolism
C9E46_RS27355	COG2962	Rard protein
C9E46_RS27385	COG0598	Magnesium transport protein CorA
C9E46_RS27390	COG3698	Phosphodiester glycosidase
C9E46_RS27395	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
C9E46_RS27400	COG0210	DNA helicase
C9E46_RS27405	COG1011	Hydrolase
C9E46_RS27415	COG3159	Protein conserved in bacteria
C9E46_RS27425	COG5567	small periplasmic lipoprotein
C9E46_RS27440	COG3072	Adenylate cyclase
C9E46_RS27450	COG1587	Uroporphyrinogen-III synthase
C9E46_RS27455	COG2959	enzyme of heme biosynthesis
C9E46_RS27460	COG3071	HemY protein
C9E46_RS27465	COG3119	arylsulfatase activity
C9E46_RS27470	COG0641	radical SAM
C9E46_RS27505	COG1113	amino acid transport
C9E46_RS27525	COG2244	polysaccharide biosynthetic process
C9E46_RS27530	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C9E46_RS27535	COG0456	acetyltransferase
C9E46_RS27540	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C9E46_RS27545	COG1088	dTDP-glucose 4,6-dehydratase activity
C9E46_RS27550	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
C9E46_RS27555	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C9E46_RS27560	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
C9E46_RS27565	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C9E46_RS27570	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C9E46_RS27580	COG3118	belongs to the thioredoxin family
C9E46_RS27595	COG0210	DNA helicase
C9E46_RS27600	COG3692	DNA binding
C9E46_RS27605	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C9E46_RS27615	COG0583	DNA-binding transcription factor activity
C9E46_RS27620	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C9E46_RS27630	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C9E46_RS27635	COG3978	acetolactate synthase activity
C9E46_RS27655	COG0606	chelatase, subunit chli
C9E46_RS27660	COG3085	chromosome segregation
C9E46_RS27700	COG2186	Transcriptional regulator
C9E46_RS27705	COG0477	Major facilitator Superfamily
C9E46_RS27710	COG1609	Transcriptional regulator
C9E46_RS27715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C9E46_RS27720	COG1879	ABC-type sugar transport system periplasmic component
C9E46_RS27725	COG1172	Belongs to the binding-protein-dependent transport system permease family
C9E46_RS27730	COG1129	ABC transporter
C9E46_RS27740	COG3158	transport of potassium into the cell
C9E46_RS27760	COG1522	sequence-specific DNA binding
C9E46_RS27765	COG0716	FMN binding
C9E46_RS27905	COG3468	outer membrane autotransporter barrel domain protein
C9E46_RS27920	COG0726	polysaccharide deacetylase
C9E46_RS27925	COG0297	glycogen (starch) synthase activity
C9E46_RS27930	COG2194	sulfuric ester hydrolase activity
C9E46_RS27935	COG1560	Kdo2-lipid A biosynthetic process
C9E46_RS27970	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C9E46_RS28045	COG2274	protein secretion by the type I secretion system
C9E46_RS28255	COG1475	DNA binding
C9E46_RS28335	COG3436	PFAM IS66 Orf2 family protein
C9E46_RS28340	COG4372	Transposase
C9E46_RS28360	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
C9E46_RS28370	COG1525	nuclease