locus-tag	class	description
GZS08_RS00010	COG0592	DNA-directed DNA polymerase activity
GZS08_RS00020	COG0187	DNA topoisomerase II activity
GZS08_RS00025	COG3753	Protein conserved in bacteria
GZS08_RS00030	COG0561	phosphatase activity
GZS08_RS00040	COG2186	Transcriptional regulator
GZS08_RS00045	COG3734	2-keto-3-deoxy-galactonokinase
GZS08_RS00050	COG0800	Aldolase
GZS08_RS00060	COG2271	Major facilitator Superfamily
GZS08_RS00065	COG0644	oxidoreductase
GZS08_RS00070	COG0823	Involved in the tonB-independent uptake of proteins
GZS08_RS00075	COG5645	(Lipo)protein
GZS08_RS00095	COG2188	Transcriptional regulator
GZS08_RS00110	COG2207	Transcriptional regulator
GZS08_RS00115	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GZS08_RS00120	COG3119	arylsulfatase activity
GZS08_RS00130	COG2149	membrane
GZS08_RS00140	COG0641	radical SAM
GZS08_RS00145	COG2814	Major facilitator Superfamily
GZS08_RS00165	COG0028	Belongs to the TPP enzyme family
GZS08_RS00170	COG0440	acetolactate synthase activity
GZS08_RS00175	COG2197	response regulator
GZS08_RS00180	COG3851	Histidine kinase
GZS08_RS00185	COG2271	Major facilitator Superfamily
GZS08_RS00190	COG2271	Major facilitator Superfamily
GZS08_RS00200	COG2252	PERMEase
GZS08_RS00220	COG1464	Belongs to the NlpA lipoprotein family
GZS08_RS00225	COG0697	spore germination
GZS08_RS00230	COG2814	Major facilitator Superfamily
GZS08_RS00245	COG2211	Major facilitator Superfamily
GZS08_RS00250	COG1501	Belongs to the glycosyl hydrolase 31 family
GZS08_RS00255	COG2982	Protein involved in outer membrane biogenesis
GZS08_RS00260	COG2233	PERMEase
GZS08_RS00265	COG0786	glutamate:sodium symporter activity
GZS08_RS00270	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GZS08_RS00275	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GZS08_RS00280	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GZS08_RS00290	COG0194	GDP metabolic process
GZS08_RS00300	COG2860	membrane
GZS08_RS00305	COG3645	SOS response
GZS08_RS00315	COG1561	YicC-like family, N-terminal region
GZS08_RS00340	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GZS08_RS00370	COG1519	Transferase
GZS08_RS00375	COG0859	PFAM glycosyl transferase family 9
GZS08_RS00380	COG0438	transferase activity, transferring glycosyl groups
GZS08_RS00385	COG0515	serine threonine protein kinase
GZS08_RS00390	COG1442	glycosyl transferase family 8
GZS08_RS00395	COG0438	transferase activity, transferring glycosyl groups
GZS08_RS00400	COG1442	glycosyl transferase family 8
GZS08_RS00405	COG1442	glycosyl transferase family 8
GZS08_RS00410	COG3642	lipopolysaccharide core region biosynthetic process
GZS08_RS00430	COG0859	PFAM glycosyl transferase family 9
GZS08_RS00435	COG0859	PFAM glycosyl transferase family 9
GZS08_RS00445	COG0156	8-amino-7-oxononanoate synthase activity
GZS08_RS00455	COG1216	Glycosyl transferase, family 2
GZS08_RS00460	COG2861	carbohydrate metabolic process
GZS08_RS00465	COG4942	peptidase
GZS08_RS00475	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GZS08_RS00480	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GZS08_RS00495	COG1045	serine acetyltransferase
GZS08_RS00500	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GZS08_RS00510	COG2186	Transcriptional regulator
GZS08_RS00515	COG1620	l-lactate permease
GZS08_RS00530	COG3722	fumarate hydratase activity
GZS08_RS00540	COG2213	PTS system mannitol-specific
GZS08_RS00540	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GZS08_RS00550	COG1566	PFAM secretion protein HlyD family protein
GZS08_RS00560	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GZS08_RS00575	COG1413	lyase activity
GZS08_RS00580	COG3209	COG3209 Rhs family protein
GZS08_RS00585	COG0625	glutathione transferase activity
GZS08_RS00595	COG3276	selenocysteine insertion sequence binding
GZS08_RS00600	COG1454	alcohol dehydrogenase
GZS08_RS00605	COG1012	belongs to the aldehyde dehydrogenase family
GZS08_RS00620	COG1566	PFAM secretion protein HlyD family protein
GZS08_RS00625	COG0583	DNA-binding transcription factor activity
GZS08_RS00630	COG3713	MltA-interacting MipA family protein
GZS08_RS00640	COG0235	Class ii aldolase
GZS08_RS00645	COG3623	hexulose-6-phosphate isomerase
GZS08_RS00650	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
GZS08_RS00655	COG1070	Carbohydrate kinase
GZS08_RS00660	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GZS08_RS00665	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GZS08_RS00670	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GZS08_RS00675	COG2731	YhcH YjgK YiaL family protein
GZS08_RS00685	COG1414	Transcriptional regulator
GZS08_RS00690	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GZS08_RS00695	COG3977	Valine--pyruvate aminotransferase
GZS08_RS00700	COG0366	Alpha amylase catalytic
GZS08_RS00705	COG2992	FlgJ-related protein
GZS08_RS00710	COG1609	Transcriptional regulator
GZS08_RS00710	COG2207	Transcriptional regulator
GZS08_RS00715	COG4214	carbohydrate transport
GZS08_RS00720	COG1129	ABC transporter
GZS08_RS00725	COG4213	ABC transporter substrate-binding protein
GZS08_RS00740	COG1070	Carbohydrate kinase
GZS08_RS00745	COG4682	membrane
GZS08_RS00750	COG4682	membrane
GZS08_RS00755	COG3274	enterobacterial common antigen metabolic process
GZS08_RS00785	COG1278	Cold shock
GZS08_RS00790	COG2944	sequence-specific DNA binding
GZS08_RS00805	COG2885	chlorophyll binding
GZS08_RS00810	COG0243	molybdopterin cofactor binding
GZS08_RS00815	COG0456	acetyltransferase
GZS08_RS00820	COG2818	Glycosylase
GZS08_RS00825	COG5571	outer membrane autotransporter
GZS08_RS00830	COG2223	nitrite transmembrane transporter activity
GZS08_RS00835	COG2194	sulfuric ester hydrolase activity
GZS08_RS00845	COG0747	negative chemotaxis
GZS08_RS00850	COG0601	transmembrane transport
GZS08_RS00855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GZS08_RS00860	COG0444	Belongs to the ABC transporter superfamily
GZS08_RS00865	COG4608	Belongs to the ABC transporter superfamily
GZS08_RS00870	COG0814	amino acid
GZS08_RS00880	COG2194	sulfuric ester hydrolase activity
GZS08_RS00905	COG1215	transferase activity, transferring glycosyl groups
GZS08_RS00910	COG1215	transferase activity, transferring glycosyl groups
GZS08_RS00920	COG0457	Tetratricopeptide repeat
GZS08_RS00920	COG3118	belongs to the thioredoxin family
GZS08_RS00925	COG2199	diguanylate cyclase activity
GZS08_RS00925	COG2200	EAL domain
GZS08_RS00935	COG0612	Peptidase, M16
GZS08_RS00940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GZS08_RS00945	COG2200	EAL domain
GZS08_RS00950	COG2982	Protein involved in outer membrane biogenesis
GZS08_RS00955	COG0477	Major facilitator Superfamily
GZS08_RS00960	COG1295	ribonuclease BN
GZS08_RS00965	COG0583	DNA-binding transcription factor activity
GZS08_RS00970	COG2197	response regulator
GZS08_RS00980	COG1858	cytochrome C peroxidase
GZS08_RS00985	COG0076	glutamate decarboxylase activity
GZS08_RS00990	COG2207	Transcriptional regulator
GZS08_RS00995	COG2207	Transcriptional regulator
GZS08_RS01000	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GZS08_RS01005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GZS08_RS01015	COG2771	luxR family
GZS08_RS01020	COG3247	response to pH
GZS08_RS01035	COG1285	pathogenesis
GZS08_RS01040	COG2197	response regulator
GZS08_RS01045	COG3065	identical protein binding
GZS08_RS01055	COG1393	Belongs to the ArsC family
GZS08_RS01060	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GZS08_RS01065	COG0640	Transcriptional regulator
GZS08_RS01075	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GZS08_RS01080	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GZS08_RS01085	COG0339	signal peptide processing
GZS08_RS01095	COG3104	oligopeptide transport
GZS08_RS01100	COG0589	response to stress
GZS08_RS01110	COG0306	phosphate transporter
GZS08_RS01115	COG2081	HI0933 family
GZS08_RS01135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GZS08_RS01140	COG0842	Transport permease protein
GZS08_RS01140	COG1129	ABC transporter
GZS08_RS01145	COG0842	Transport permease protein
GZS08_RS01150	COG5433	transposase activity
GZS08_RS01165	COG3209	COG3209 Rhs family protein
GZS08_RS01175	COG1124	(ABC) transporter
GZS08_RS01180	COG0444	Belongs to the ABC transporter superfamily
GZS08_RS01185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GZS08_RS01190	COG0601	transmembrane transport
GZS08_RS01195	COG0747	negative chemotaxis
GZS08_RS01200	COG2091	lysine biosynthetic process via aminoadipic acid
GZS08_RS01205	COG0628	permease
GZS08_RS01210	COG0477	Major facilitator Superfamily
GZS08_RS01220	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GZS08_RS01230	COG2217	Heavy metal translocating P-type atpase
GZS08_RS01235	COG3714	YhhN family
GZS08_RS01245	COG3776	membrane
GZS08_RS01250	COG0742	ribosomal rna small subunit methyltransferase
GZS08_RS01255	COG0552	protein localization to endoplasmic reticulum
GZS08_RS01260	COG2884	Cell division ATP-binding protein ftsE
GZS08_RS01265	COG2177	Part of the ABC transporter FtsEX involved in
GZS08_RS01270	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GZS08_RS01275	COG0683	leucine binding
GZS08_RS01280	COG0456	acetyltransferase
GZS08_RS01285	COG0683	leucine binding
GZS08_RS01290	COG0559	Belongs to the binding-protein-dependent transport system permease family
GZS08_RS01295	COG4177	L-phenylalanine transmembrane transporter activity
GZS08_RS01300	COG0411	ABC transporter
GZS08_RS01305	COG0410	ABC transporter
GZS08_RS01310	COG1653	transport
GZS08_RS01315	COG1175	transmembrane transport
GZS08_RS01320	COG0395	ABC-type sugar transport system, permease component
GZS08_RS01325	COG3842	ATPase activity
GZS08_RS01330	COG0584	glycerophosphoryl diester phosphodiesterase
GZS08_RS01340	COG0405	Gamma-glutamyltransferase
GZS08_RS01360	COG3157	Type VI secretion system effector, Hcp
GZS08_RS01370	COG1247	-acetyltransferase
GZS08_RS01375	COG0673	inositol 2-dehydrogenase activity
GZS08_RS01380	COG1741	Belongs to the pirin family
GZS08_RS01385	COG1609	Transcriptional regulator
GZS08_RS01390	COG3265	gluconokinase activity
GZS08_RS01395	COG2610	gluconate transmembrane transporter activity
GZS08_RS01400	COG2095	MarC family integral membrane protein
GZS08_RS01405	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GZS08_RS01430	COG0058	SHG alpha-glucan phosphorylase activity
GZS08_RS01440	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GZS08_RS01455	COG1349	DNA-binding transcription factor activity
GZS08_RS01460	COG4650	regulator
GZS08_RS01465	COG1690	Belongs to the RtcB family
GZS08_RS01480	COG0058	SHG alpha-glucan phosphorylase activity
GZS08_RS01485	COG1640	4-alpha-glucanotransferase
GZS08_RS01490	COG2610	gluconate transmembrane transporter activity
GZS08_RS01500	COG1040	competence protein
GZS08_RS01510	COG5464	transposase or invertase
GZS08_RS01520	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GZS08_RS01525	COG1918	ferrous iron import across plasma membrane
GZS08_RS01530	COG2183	response to ionizing radiation
GZS08_RS01535	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GZS08_RS01555	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
GZS08_RS01565	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GZS08_RS01570	COG1011	Hydrolase
GZS08_RS01580	COG0494	nUDIX hydrolase
GZS08_RS01585	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GZS08_RS01590	COG4972	Pilus assembly protein
GZS08_RS01595	COG3166	PFAM Fimbrial assembly family protein
GZS08_RS01610	COG4796	Type ii and iii secretion system protein
GZS08_RS01625	COG3266	domain, Protein
GZS08_RS01630	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GZS08_RS01635	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GZS08_RS01640	COG0546	phosphoglycolate phosphatase activity
GZS08_RS01645	COG0180	Tryptophanyl-tRNA synthetase
GZS08_RS01650	COG2188	Transcriptional regulator
GZS08_RS01660	COG3457	Alanine racemase
GZS08_RS01665	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GZS08_RS01670	COG1735	metal-dependent hydrolase with the TIM-barrel fold
GZS08_RS01685	COG0626	cystathionine gamma-synthase activity
GZS08_RS01690	COG2188	Transcriptional regulator
GZS08_RS01695	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GZS08_RS01700	COG1082	Xylose isomerase domain protein TIM barrel
GZS08_RS01705	COG2222	sugar isomerase
GZS08_RS01710	COG0531	amino acid
GZS08_RS01725	COG2116	formate transmembrane transporter activity
GZS08_RS01730	COG2146	nitrite reductase [NAD(P)H] activity
GZS08_RS01735	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GZS08_RS01745	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GZS08_RS01755	COG2184	nucleotidyltransferase activity
GZS08_RS01760	COG0512	Glutamine amidotransferase of anthranilate synthase
GZS08_RS01765	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GZS08_RS01770	COG1289	transmembrane transporter activity
GZS08_RS01775	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GZS08_RS01780	COG1765	OsmC-like protein
GZS08_RS01785	COG3954	Phosphoribulokinase
GZS08_RS01795	COG0429	hydrolase of the alpha beta-hydrolase fold
GZS08_RS01800	COG0488	(ABC) transporter
GZS08_RS01815	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
GZS08_RS01820	COG1047	Peptidyl-prolyl cis-trans
GZS08_RS01830	COG0545	Peptidyl-prolyl cis-trans isomerase
GZS08_RS01835	COG2964	Protein conserved in bacteria
GZS08_RS01875	COG3979	chitinase
GZS08_RS01880	COG2906	2 iron, 2 sulfur cluster binding
GZS08_RS01885	COG2193	ferroxidase activity
GZS08_RS01890	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GZS08_RS01895	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GZS08_RS01900	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GZS08_RS01905	COG3156	type II secretion system protein K
GZS08_RS01910	COG4795	General secretion pathway protein
GZS08_RS01915	COG2165	general secretion pathway protein
GZS08_RS01920	COG2165	general secretion pathway protein
GZS08_RS01925	COG2165	general secretion pathway protein
GZS08_RS01930	COG1459	type II secretion system
GZS08_RS01935	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GZS08_RS01940	COG1450	Type ii and iii secretion system protein
GZS08_RS01945	COG3031	protein transport across the cell outer membrane
GZS08_RS01950	COG3267	Type II secretory pathway component ExeA
GZS08_RS01950	COG3409	Peptidoglycan-binding domain 1 protein
GZS08_RS01975	COG0089	rRNA binding
GZS08_RS02065	COG0201	protein transport
GZS08_RS02105	COG0789	Transcriptional regulator
GZS08_RS02110	COG3036	rescue of stalled ribosome
GZS08_RS02120	COG0569	domain protein
GZS08_RS02140	COG0758	DNA mediated transformation
GZS08_RS02150	COG0551	DNA topoisomerase type I activity
GZS08_RS02170	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GZS08_RS02210	COG1126	abc transporter atp-binding protein
GZS08_RS02215	COG0765	amino acid transport
GZS08_RS02220	COG4597	amino acid ABC transporter
GZS08_RS02225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GZS08_RS02235	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GZS08_RS02255	COG2189	Belongs to the N(4) N(6)-methyltransferase family
GZS08_RS02265	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GZS08_RS02275	COG4145	pantothenate transmembrane transporter activity
GZS08_RS02280	COG3924	membrane
GZS08_RS02285	COG0439	Biotin carboxylase
GZS08_RS02290	COG0511	ligase activity, forming carbon-carbon bonds
GZS08_RS02295	COG0604	alcohol dehydrogenase
GZS08_RS02300	COG2200	EAL domain
GZS08_RS02300	COG2199	diguanylate cyclase activity
GZS08_RS02305	COG1077	Cell shape determining protein MreB Mrl
GZS08_RS02310	COG1792	Involved in formation and maintenance of cell shape
GZS08_RS02315	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GZS08_RS02320	COG0424	maF-like protein
GZS08_RS02325	COG1530	ribonuclease E activity
GZS08_RS02330	COG3164	Protein of unknown function
GZS08_RS02335	COG0312	modulator of DNA gyrase
GZS08_RS02340	COG0583	DNA-binding transcription factor activity
GZS08_RS02360	COG2732	(Barnase) inhibitor
GZS08_RS02380	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GZS08_RS02385	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GZS08_RS02390	COG3105	Protein conserved in bacteria
GZS08_RS02395	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GZS08_RS02410	COG0625	glutathione transferase activity
GZS08_RS02415	COG2969	positive regulation of protein catabolic process
GZS08_RS02420	COG3069	C4-dicarboxylate transmembrane transporter activity
GZS08_RS02450	COG2731	YhcH YjgK YiaL family protein
GZS08_RS02455	COG4804	nuclease activity
GZS08_RS02465	COG3344	reverse transcriptase
GZS08_RS02480	COG3539	Fimbrial protein
GZS08_RS02490	COG3188	usher protein
GZS08_RS02495	COG3121	Chaperone
GZS08_RS02500	COG3539	Fimbrial protein
GZS08_RS02505	COG0493	'glutamate synthase
GZS08_RS02510	COG0067	glutamate synthase
GZS08_RS02510	COG0069	glutamate synthase activity
GZS08_RS02510	COG0070	glutamate synthase
GZS08_RS02515	COG1242	4 iron, 4 sulfur cluster binding
GZS08_RS02520	COG0784	Response regulator, receiver
GZS08_RS02520	COG2198	Histidine kinase
GZS08_RS02520	COG5002	protein histidine kinase activity
GZS08_RS02525	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GZS08_RS02535	COG0515	serine threonine protein kinase
GZS08_RS02540	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GZS08_RS02555	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GZS08_RS02560	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GZS08_RS02565	COG1137	ATPase activity
GZS08_RS02570	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GZS08_RS02575	COG3117	lipopolysaccharide transmembrane transporter activity
GZS08_RS02580	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GZS08_RS02585	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GZS08_RS02585	COG0517	IMP dehydrogenase activity
GZS08_RS02590	COG0530	calcium, potassium:sodium antiporter activity
GZS08_RS02595	COG1127	ABC transporter
GZS08_RS02600	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GZS08_RS02605	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GZS08_RS02610	COG2854	intermembrane phospholipid transfer
GZS08_RS02615	COG3113	response to antibiotic
GZS08_RS02620	COG5007	Belongs to the BolA IbaG family
GZS08_RS02630	COG3423	Transcriptional regulator
GZS08_RS02635	COG0142	geranyltranstransferase activity
GZS08_RS02650	COG0697	spore germination
GZS08_RS02660	COG2027	D-alanyl-D-alanine carboxypeptidase
GZS08_RS02665	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GZS08_RS02670	COG1534	Rna-binding protein
GZS08_RS02680	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GZS08_RS02685	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GZS08_RS02695	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GZS08_RS02725	COG0195	Participates in both transcription termination and antitermination
GZS08_RS02765	COG0513	Belongs to the DEAD box helicase family
GZS08_RS02770	COG0814	amino acid
GZS08_RS02775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GZS08_RS02780	COG0826	peptidase U32
GZS08_RS02785	COG0826	peptidase U32
GZS08_RS02790	COG3154	lipid carrier protein
GZS08_RS02795	COG3153	acetyltransferase
GZS08_RS02810	COG0693	protein deglycase activity
GZS08_RS02815	COG0702	epimerase
GZS08_RS02820	COG0701	Predicted permease
GZS08_RS02825	COG2823	Periplasmic or secreted lipoprotein
GZS08_RS02840	COG3107	peptidoglycan biosynthetic process
GZS08_RS02845	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GZS08_RS02850	COG3539	Fimbrial protein
GZS08_RS02855	COG3188	usher protein
GZS08_RS02860	COG3121	Chaperone
GZS08_RS02865	COG3539	Fimbrial protein
GZS08_RS02870	COG0363	glucosamine-6-phosphate deaminase activity
GZS08_RS02875	COG3716	PTS system mannose fructose sorbose family IID component
GZS08_RS02890	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GZS08_RS02900	COG2222	sugar isomerase
GZS08_RS02905	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GZS08_RS02910	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GZS08_RS02915	COG3716	PTS system mannose fructose sorbose family IID component
GZS08_RS02925	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GZS08_RS02935	COG1349	DNA-binding transcription factor activity
GZS08_RS02945	COG2002	toxin-antitoxin pair type II binding
GZS08_RS02950	COG2721	sulfolactate sulfo-lyase activity
GZS08_RS02955	COG2271	Major facilitator Superfamily
GZS08_RS02965	COG2084	Dehydrogenase
GZS08_RS02970	COG1929	Belongs to the glycerate kinase type-1 family
GZS08_RS02995	COG0583	DNA-binding transcription factor activity
GZS08_RS03000	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GZS08_RS03010	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GZS08_RS03015	COG1882	Formate acetyltransferase
GZS08_RS03020	COG0251	oxidation-reduction process
GZS08_RS03025	COG1760	l-serine dehydratase
GZS08_RS03030	COG0814	amino acid
GZS08_RS03045	COG1741	Belongs to the pirin family
GZS08_RS03050	COG0583	DNA-binding transcription factor activity
GZS08_RS03055	COG3152	Membrane
GZS08_RS03065	COG3152	Membrane
GZS08_RS03070	COG0435	Glutathione S-transferase
GZS08_RS03075	COG2259	Doxx family
GZS08_RS03085	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
GZS08_RS03090	COG4575	ribosome binding
GZS08_RS03095	COG1422	Protein of unknown function (DUF1090)
GZS08_RS03105	COG0586	Pfam SNARE associated Golgi protein
GZS08_RS03110	COG2186	Transcriptional regulator
GZS08_RS03115	COG2271	Major facilitator Superfamily
GZS08_RS03125	COG2721	sulfolactate sulfo-lyase activity
GZS08_RS03135	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GZS08_RS03140	COG0861	Integral membrane protein TerC family
GZS08_RS03145	COG0673	inositol 2-dehydrogenase activity
GZS08_RS03150	COG2949	membrane
GZS08_RS03155	COG1451	nucleotide metabolic process
GZS08_RS03165	COG4680	protein conserved in bacteria
GZS08_RS03170	COG5499	transcription regulator containing HTH domain
GZS08_RS03175	COG1902	pentaerythritol trinitrate reductase activity
GZS08_RS03175	COG0446	pyridine nucleotide-disulphide oxidoreductase
GZS08_RS03180	COG3408	Glycogen debranching enzyme
GZS08_RS03180	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
GZS08_RS03190	COG0531	amino acid
GZS08_RS03195	COG2731	YhcH YjgK YiaL family protein
GZS08_RS03200	COG3250	beta-galactosidase activity
GZS08_RS03205	COG1609	Transcriptional regulator
GZS08_RS03210	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GZS08_RS03220	COG0840	transmembrane signaling receptor activity
GZS08_RS03225	COG1695	Transcriptional regulator
GZS08_RS03230	COG2375	cellular response to nickel ion
GZS08_RS03245	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GZS08_RS03250	COG0358	DNA primase activity
GZS08_RS03255	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GZS08_RS03265	COG0471	metal ion transport
GZS08_RS03270	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GZS08_RS03275	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GZS08_RS03280	COG0583	DNA-binding transcription factor activity
GZS08_RS03290	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GZS08_RS03305	COG4991	sh3 domain protein
GZS08_RS03310	COG3025	triphosphatase activity
GZS08_RS03335	COG2268	Band 7 protein
GZS08_RS03340	COG1585	Membrane protein implicated in regulation of membrane protease activity
GZS08_RS03350	COG3539	Fimbrial protein
GZS08_RS03355	COG3121	Chaperone
GZS08_RS03375	COG3539	Fimbrial protein
GZS08_RS03380	COG2960	long-chain fatty acid transporting porin activity
GZS08_RS03400	COG3384	dioxygenase
GZS08_RS03405	COG0754	glutathionylspermidine amidase activity
GZS08_RS03415	COG1538	Outer membrane efflux protein
GZS08_RS03420	COG0494	nUDIX hydrolase
GZS08_RS03425	COG3151	Protein conserved in bacteria
GZS08_RS03430	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GZS08_RS03435	COG3150	esterase
GZS08_RS03440	COG0187	DNA topoisomerase II activity
GZS08_RS03445	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GZS08_RS03450	COG2249	NAD(P)H dehydrogenase (quinone) activity
GZS08_RS03460	COG0642	Histidine kinase
GZS08_RS03465	COG0745	RESPONSE REGULATOR receiver
GZS08_RS03470	COG3111	PFAM Bacterial OB fold (BOF) protein
GZS08_RS03475	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
GZS08_RS03485	COG2944	sequence-specific DNA binding
GZS08_RS03490	COG4166	transmembrane transport
GZS08_RS03495	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GZS08_RS03500	COG0204	Acyl-transferase
GZS08_RS03505	COG2132	Multicopper oxidase
GZS08_RS03510	COG1032	radical SAM domain protein
GZS08_RS03515	COG4238	major outer membrane lipoprotein
GZS08_RS03525	COG0656	L-ascorbic acid biosynthetic process
GZS08_RS03530	COG1979	alcohol dehydrogenase
GZS08_RS03535	COG2207	Transcriptional regulator
GZS08_RS03540	COG0586	Pfam SNARE associated Golgi protein
GZS08_RS03545	COG0626	cystathionine gamma-synthase activity
GZS08_RS03550	COG0811	peptide transport
GZS08_RS03555	COG0848	biopolymer transport protein
GZS08_RS03560	COG1028	Short-chain dehydrogenase reductase Sdr
GZS08_RS03570	COG0667	Aldo Keto reductase
GZS08_RS03590	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
GZS08_RS03595	COG0437	4 iron, 4 sulfur cluster binding
GZS08_RS03600	COG5557	Pfam Polysulphide reductase, NrfD
GZS08_RS03605	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
GZS08_RS03610	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GZS08_RS03615	COG1773	rubredoxin
GZS08_RS03625	COG0298	carbon dioxide binding
GZS08_RS03630	COG0625	glutathione transferase activity
GZS08_RS03635	COG0754	glutathionylspermidine amidase activity
GZS08_RS03640	COG0306	phosphate transporter
GZS08_RS03645	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GZS08_RS03650	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GZS08_RS03655	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GZS08_RS03660	COG2244	polysaccharide biosynthetic process
GZS08_RS03670	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GZS08_RS03675	COG0795	lipopolysaccharide-transporting ATPase activity
GZS08_RS03685	COG0156	8-amino-7-oxononanoate synthase activity
GZS08_RS03690	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GZS08_RS03700	COG0318	PFAM AMP-dependent synthetase and ligase
GZS08_RS03705	COG0456	acetyltransferase
GZS08_RS03710	COG2186	Transcriptional regulator
GZS08_RS03715	COG0277	FAD linked oxidase domain protein
GZS08_RS03720	COG0277	FAD linked oxidase domain protein
GZS08_RS03725	COG0247	lactate metabolic process
GZS08_RS03730	COG3193	protein, possibly involved in utilization of glycolate and propanediol
GZS08_RS03735	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GZS08_RS03740	COG1620	l-lactate permease
GZS08_RS03745	COG3064	Membrane
GZS08_RS03755	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GZS08_RS03765	COG3031	protein transport across the cell outer membrane
GZS08_RS03780	COG1459	type II secretion system
GZS08_RS03785	COG2165	general secretion pathway protein
GZS08_RS03815	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GZS08_RS03850	COG2003	Belongs to the UPF0758 family
GZS08_RS03875	COG2378	regulation of single-species biofilm formation
GZS08_RS03880	COG3596	GTP binding
GZS08_RS03900	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GZS08_RS03905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GZS08_RS03910	COG2313	pseudouridylate synthase activity
GZS08_RS03915	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GZS08_RS03920	COG1522	sequence-specific DNA binding
GZS08_RS03920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GZS08_RS03970	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GZS08_RS03975	COG2207	Transcriptional regulator
GZS08_RS03980	COG2972	Histidine kinase
GZS08_RS04000	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GZS08_RS04005	COG1882	Formate acetyltransferase
GZS08_RS04010	COG0693	protein deglycase activity
GZS08_RS04020	COG1012	belongs to the aldehyde dehydrogenase family
GZS08_RS04055	COG4820	ethanolamine utilization protein (EutJ)
GZS08_RS04060	COG4869	propanediol catabolic process
GZS08_RS04110	COG3969	phosphoadenosine phosphosulfate
GZS08_RS04115	COG1475	DNA binding
GZS08_RS04135	COG1201	RNA secondary structure unwinding
GZS08_RS04160	COG2194	sulfuric ester hydrolase activity
GZS08_RS04165	COG0582	viral genome integration into host DNA
GZS08_RS04175	COG1811	Na channel or pump
GZS08_RS04180	COG1982	Orn Lys Arg decarboxylase major
GZS08_RS04185	COG2211	Major facilitator Superfamily
GZS08_RS04200	COG1194	a g-specific adenine glycosylase
GZS08_RS04210	COG3171	Protein conserved in bacteria
GZS08_RS04220	COG0252	asparaginase activity
GZS08_RS04230	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GZS08_RS04235	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GZS08_RS04245	COG0762	integral membrane protein
GZS08_RS04250	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GZS08_RS04255	COG2805	Type II/IV secretion system protein
GZS08_RS04270	COG0189	ligase activity
GZS08_RS04275	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GZS08_RS04280	COG2356	endonuclease I
GZS08_RS04290	COG2814	Major facilitator Superfamily
GZS08_RS04310	COG1166	arginine decarboxylase activity
GZS08_RS04320	COG0501	Belongs to the peptidase M48B family
GZS08_RS04325	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GZS08_RS04330	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GZS08_RS04335	COG2213	PTS system mannitol-specific
GZS08_RS04340	COG1063	alcohol dehydrogenase
GZS08_RS04345	COG1494	fructose-1,6-bisphosphatase
GZS08_RS04350	COG3722	fumarate hydratase activity
GZS08_RS04355	COG1072	(Pantothenic acid kinase))
GZS08_RS04370	COG0191	fructose-bisphosphate aldolase activity
GZS08_RS04375	COG0668	transmembrane transport
GZS08_RS04380	COG1279	arginine transmembrane transporter activity
GZS08_RS04385	COG2968	Membrane
GZS08_RS04390	COG0583	DNA-binding transcription factor activity
GZS08_RS04395	COG0427	acetyl-CoA hydrolase
GZS08_RS04400	COG1024	Enoyl-CoA hydratase
GZS08_RS04405	COG1703	isobutyryl-CoA mutase activity
GZS08_RS04410	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GZS08_RS04410	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GZS08_RS04430	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GZS08_RS04440	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GZS08_RS04460	COG0006	proline dipeptidase activity
GZS08_RS04465	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GZS08_RS04470	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GZS08_RS04495	COG1028	Short-chain dehydrogenase reductase Sdr
GZS08_RS04500	COG2723	6-phospho-beta-galactosidase activity
GZS08_RS04510	COG1272	protein, Hemolysin III
GZS08_RS04520	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GZS08_RS04530	COG0716	FMN binding
GZS08_RS04535	COG4974	Belongs to the 'phage' integrase family
GZS08_RS04540	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GZS08_RS04545	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GZS08_RS04555	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GZS08_RS04575	COG2233	PERMEase
GZS08_RS04580	COG0493	'glutamate synthase
GZS08_RS04580	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GZS08_RS04585	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GZS08_RS04590	COG2252	PERMEase
GZS08_RS04595	COG0402	S-adenosylhomocysteine deaminase activity
GZS08_RS04600	COG2233	PERMEase
GZS08_RS04605	COG2080	2 iron, 2 sulfur cluster binding
GZS08_RS04605	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GZS08_RS04610	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GZS08_RS04615	COG0402	S-adenosylhomocysteine deaminase activity
GZS08_RS04620	COG0493	'glutamate synthase
GZS08_RS04620	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GZS08_RS04625	COG2068	MobA-Related Protein
GZS08_RS04630	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GZS08_RS04635	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GZS08_RS04635	COG3608	succinylglutamate desuccinylase aspartoacylase
GZS08_RS04640	COG0549	Belongs to the carbamate kinase family
GZS08_RS04650	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GZS08_RS04655	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GZS08_RS04660	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GZS08_RS04665	COG3829	transcription factor binding
GZS08_RS04670	COG2080	2 iron, 2 sulfur cluster binding
GZS08_RS04675	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GZS08_RS04680	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GZS08_RS04685	COG4942	peptidase
GZS08_RS04695	COG4974	Belongs to the 'phage' integrase family
GZS08_RS04705	COG1484	DNA-dependent DNA replication
GZS08_RS04710	COG4584	PFAM Integrase catalytic
GZS08_RS04735	COG3385	transposase activity
GZS08_RS04835	COG3710	Transcriptional regulator
GZS08_RS04835	COG0457	Tetratricopeptide repeat
GZS08_RS04840	COG0457	Tetratricopeptide repeat
GZS08_RS04865	COG3710	Transcriptional regulator
GZS08_RS04870	COG2771	luxR family
GZS08_RS04875	COG0814	amino acid
GZS08_RS04880	COG0183	Belongs to the thiolase family
GZS08_RS04890	COG1028	Short-chain dehydrogenase reductase Sdr
GZS08_RS04895	COG2814	Major facilitator Superfamily
GZS08_RS04900	COG1794	racemase activity, acting on amino acids and derivatives
GZS08_RS04905	COG0583	DNA-binding transcription factor activity
GZS08_RS04915	COG1609	Transcriptional regulator
GZS08_RS04930	COG0667	Aldo Keto reductase
GZS08_RS04940	COG0861	Integral membrane protein TerC family
GZS08_RS04955	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
GZS08_RS04970	COG2165	general secretion pathway protein
GZS08_RS04975	COG4795	General secretion pathway protein
GZS08_RS04985	COG4967	type IV pilus modification protein PilV
GZS08_RS04990	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GZS08_RS04995	COG1025	Belongs to the peptidase M16 family
GZS08_RS05000	COG1074	ATP-dependent DNA helicase activity
GZS08_RS05005	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GZS08_RS05010	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GZS08_RS05010	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GZS08_RS05015	COG0860	N-Acetylmuramoyl-L-alanine amidase
GZS08_RS05030	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GZS08_RS05035	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GZS08_RS05040	COG2166	iron-sulfur cluster assembly
GZS08_RS05045	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GZS08_RS05055	COG0583	DNA-binding transcription factor activity
GZS08_RS05060	COG2363	Small membrane protein
GZS08_RS05070	COG1349	DNA-binding transcription factor activity
GZS08_RS05080	COG1070	Carbohydrate kinase
GZS08_RS05090	COG0738	Major facilitator superfamily
GZS08_RS05095	COG0235	Class ii aldolase
GZS08_RS05100	COG1454	alcohol dehydrogenase
GZS08_RS05110	COG1760	l-serine dehydratase
GZS08_RS05115	COG0814	amino acid
GZS08_RS05120	COG1611	Belongs to the LOG family
GZS08_RS05135	COG3098	single-species biofilm formation
GZS08_RS05140	COG0564	pseudouridine synthase activity
GZS08_RS05145	COG0716	FMN binding
GZS08_RS05150	COG2271	Major facilitator Superfamily
GZS08_RS05155	COG4948	Mandelate Racemase Muconate Lactonizing
GZS08_RS05160	COG4948	Mandelate Racemase Muconate Lactonizing
GZS08_RS05165	COG4999	Histidine kinase
GZS08_RS05165	COG3850	Histidine kinase
GZS08_RS05165	COG3437	response regulator, receiver
GZS08_RS05165	COG2205	protein histidine kinase activity
GZS08_RS05170	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GZS08_RS05175	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GZS08_RS05180	COG2336	PFAM SpoVT AbrB
GZS08_RS05185	COG2337	Toxic component of a toxin-antitoxin (TA) module
GZS08_RS05190	COG3956	TIGRFAM MazG family protein
GZS08_RS05205	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GZS08_RS05215	COG0602	queuosine metabolic process
GZS08_RS05220	COG1070	Carbohydrate kinase
GZS08_RS05225	COG2223	nitrite transmembrane transporter activity
GZS08_RS05230	COG1028	Short-chain dehydrogenase reductase Sdr
GZS08_RS05235	COG0277	FAD linked oxidase domain protein
GZS08_RS05240	COG0477	Major facilitator Superfamily
GZS08_RS05245	COG2086	electron transfer activity
GZS08_RS05250	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GZS08_RS05255	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GZS08_RS05260	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
GZS08_RS05265	COG0644	oxidoreductase
GZS08_RS05270	COG0720	synthase
GZS08_RS05290	COG1203	CRISPR-associated helicase, Cas3
GZS08_RS05305	COG1857	crispr-associated protein
GZS08_RS05320	COG1518	maintenance of DNA repeat elements
GZS08_RS05325	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GZS08_RS05330	COG2234	aminopeptidase activity
GZS08_RS05385	COG4942	peptidase
GZS08_RS05385	COG1388	LysM domain
GZS08_RS05390	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GZS08_RS05395	COG2610	gluconate transmembrane transporter activity
GZS08_RS05400	COG3622	Belongs to the hyi family
GZS08_RS05405	COG0235	Class ii aldolase
GZS08_RS05410	COG3395	kinase activity
GZS08_RS05415	COG2084	Dehydrogenase
GZS08_RS05420	COG1349	DNA-binding transcription factor activity
GZS08_RS05425	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GZS08_RS05445	COG3604	Transcriptional regulator
GZS08_RS05450	COG0309	Hydrogenase expression formation protein (HypE)
GZS08_RS05455	COG0409	Hydrogenase expression formation protein
GZS08_RS05460	COG0298	carbon dioxide binding
GZS08_RS05465	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GZS08_RS05470	COG0375	protein maturation
GZS08_RS05480	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GZS08_RS05485	COG0651	ATP synthesis coupled electron transport
GZS08_RS05490	COG0650	Formate hydrogenlyase subunit 4
GZS08_RS05495	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
GZS08_RS05495	COG3261	NADH dehydrogenase
GZS08_RS05500	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GZS08_RS05505	COG3260	NADH ubiquinone oxidoreductase 20
GZS08_RS05515	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GZS08_RS05520	COG2723	6-phospho-beta-galactosidase activity
GZS08_RS05525	COG1263	PTS System
GZS08_RS05525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GZS08_RS05530	COG1609	Transcriptional regulator
GZS08_RS05535	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GZS08_RS05540	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
GZS08_RS05560	COG0517	IMP dehydrogenase activity
GZS08_RS05560	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GZS08_RS05565	COG1349	DNA-binding transcription factor activity
GZS08_RS05570	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
GZS08_RS05575	COG1028	Short-chain dehydrogenase reductase Sdr
GZS08_RS05580	COG3731	PTS system glucitol sorbitol-specific IIA component
GZS08_RS05585	COG3732	PTS system glucitol sorbitol-specific
GZS08_RS05590	COG3730	PTS system glucitol sorbitol-specific
GZS08_RS05595	COG2951	lytic endotransglycosylase activity
GZS08_RS05600	COG1546	Belongs to the CinA family
GZS08_RS05620	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GZS08_RS05650	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GZS08_RS05655	COG1238	metal cluster binding
GZS08_RS05670	COG2814	Major facilitator Superfamily
GZS08_RS05675	COG1566	PFAM secretion protein HlyD family protein
GZS08_RS05680	COG1846	Transcriptional regulator
GZS08_RS05695	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GZS08_RS05700	COG2814	Major facilitator Superfamily
GZS08_RS05705	COG2113	Glycine betaine
GZS08_RS05710	COG4176	ABC-type proline glycine betaine transport system permease component
GZS08_RS05715	COG4175	Glycine betaine
GZS08_RS05720	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GZS08_RS05725	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GZS08_RS05735	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GZS08_RS05740	COG4575	ribosome binding
GZS08_RS05755	COG2916	Histone family protein nucleoid-structuring protein H-NS
GZS08_RS05760	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GZS08_RS05765	COG0640	Transcriptional regulator
GZS08_RS05770	COG0401	homolog of Blt101
GZS08_RS05775	COG1652	LysM domain
GZS08_RS05780	COG1802	Transcriptional regulator
GZS08_RS05785	COG1113	amino acid transport
GZS08_RS05790	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GZS08_RS05795	COG1012	belongs to the aldehyde dehydrogenase family
GZS08_RS05800	COG0579	oxidoreductase
GZS08_RS05840	COG3468	outer membrane autotransporter barrel domain protein
GZS08_RS05855	COG2867	negative regulation of translational initiation
GZS08_RS05865	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GZS08_RS05870	COG0497	DNA recombination
GZS08_RS05885	COG4536	flavin adenine dinucleotide binding
GZS08_RS05890	COG4137	Cytochrome C assembly protein
GZS08_RS05895	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GZS08_RS05920	COG2885	chlorophyll binding
GZS08_RS05925	COG2199	diguanylate cyclase activity
GZS08_RS05940	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GZS08_RS05945	COG1605	Chorismate mutase
GZS08_RS05945	COG0287	Prephenate dehydrogenase
GZS08_RS05950	COG1605	Chorismate mutase
GZS08_RS05950	COG0077	Prephenate dehydratase
GZS08_RS05960	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GZS08_RS05965	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GZS08_RS05970	COG0564	pseudouridine synthase activity
GZS08_RS05975	COG1496	oxidoreductase activity
GZS08_RS05980	COG0542	response to heat
GZS08_RS06005	COG0477	Major facilitator Superfamily
GZS08_RS06010	COG5544	Lipoprotein
GZS08_RS06015	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GZS08_RS06020	COG0045	succinate-CoA ligase (ADP-forming) activity
GZS08_RS06020	COG1042	CoA-binding domain protein
GZS08_RS06020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GZS08_RS06025	COG3148	PFAM DTW domain containing protein
GZS08_RS06030	COG3118	belongs to the thioredoxin family
GZS08_RS06035	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GZS08_RS06055	COG0583	DNA-binding transcription factor activity
GZS08_RS06060	COG0513	Belongs to the DEAD box helicase family
GZS08_RS06070	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GZS08_RS06080	COG1595	DNA-templated transcription, initiation
GZS08_RS06085	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
GZS08_RS06090	COG3026	antisigma factor binding
GZS08_RS06095	COG3086	response to oxidative stress
GZS08_RS06105	COG0681	Belongs to the peptidase S26 family
GZS08_RS06125	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GZS08_RS06140	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GZS08_RS06145	COG1737	Transcriptional regulator
GZS08_RS06150	COG0560	Phosphoserine phosphatase
GZS08_RS06165	COG0047	phosphoribosylformylglycinamidine synthase activity
GZS08_RS06165	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GZS08_RS06170	COG2205	protein histidine kinase activity
GZS08_RS06175	COG3170	Tfp pilus assembly protein FimV
GZS08_RS06180	COG2204	response regulator
GZS08_RS06185	COG0347	Belongs to the P(II) protein family
GZS08_RS06190	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GZS08_RS06190	COG1017	nitric oxide dioxygenase activity
GZS08_RS06200	COG1940	carbohydrate kinase activity
GZS08_RS06205	COG0457	Tetratricopeptide repeat
GZS08_RS06210	COG1879	ABC-type sugar transport system periplasmic component
GZS08_RS06215	COG1129	ABC transporter
GZS08_RS06220	COG1172	Belongs to the binding-protein-dependent transport system permease family
GZS08_RS06225	COG1063	alcohol dehydrogenase
GZS08_RS06230	COG2017	converts alpha-aldose to the beta-anomer
GZS08_RS06235	COG2259	Doxx family
GZS08_RS06260	COG4638	Rieske (2fe-2S)
GZS08_RS06265	COG0583	DNA-binding transcription factor activity
GZS08_RS06270	COG2814	Major facilitator Superfamily
GZS08_RS06275	COG3711	transcriptional antiterminator
GZS08_RS06280	COG1073	alpha beta
GZS08_RS06285	COG0483	inositol monophosphate 1-phosphatase activity
GZS08_RS06305	COG0822	iron-sulfur transferase activity
GZS08_RS06325	COG0633	Ferredoxin
GZS08_RS06330	COG2975	iron-sulfur cluster assembly
GZS08_RS06345	COG2897	thiosulfate sulfurtransferase activity
GZS08_RS06350	COG2373	Large extracellular alpha-helical protein
GZS08_RS06355	COG4953	penicillin-binding protein 1C
GZS08_RS06385	COG2976	Protein conserved in bacteria
GZS08_RS06400	COG1645	bacterial-type flagellum-dependent swarming motility
GZS08_RS06410	COG0517	IMP dehydrogenase activity
GZS08_RS06410	COG0516	GMP reductase activity
GZS08_RS06425	COG3133	Outer membrane lipoprotein
GZS08_RS06440	COG2200	EAL domain
GZS08_RS06445	COG0248	Ppx GppA phosphatase
GZS08_RS06450	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GZS08_RS06455	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GZS08_RS06470	COG2233	PERMEase
GZS08_RS06480	COG1393	Belongs to the ArsC family
GZS08_RS06485	COG4783	chaperone-mediated protein folding
GZS08_RS06490	COG0628	permease
GZS08_RS06495	COG2116	formate transmembrane transporter activity
GZS08_RS06500	COG3604	Transcriptional regulator
GZS08_RS06510	COG3260	NADH ubiquinone oxidoreductase 20
GZS08_RS06515	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GZS08_RS06520	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
GZS08_RS06520	COG3261	NADH dehydrogenase
GZS08_RS06525	COG0651	ATP synthesis coupled electron transport
GZS08_RS06530	COG4237	Hydrogenase 4 membrane
GZS08_RS06535	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GZS08_RS06540	COG0650	Formate hydrogenlyase subunit 4
GZS08_RS06545	COG0651	ATP synthesis coupled electron transport
GZS08_RS06550	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GZS08_RS06555	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GZS08_RS06560	COG2716	regulation of RNA biosynthetic process
GZS08_RS06570	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GZS08_RS06580	COG2321	neutral zinc metallopeptidase
GZS08_RS06585	COG1444	tRNA N-acetyltransferase activity
GZS08_RS06590	COG0400	carboxylic ester hydrolase activity
GZS08_RS06605	COG1393	Belongs to the ArsC family
GZS08_RS06615	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GZS08_RS06620	COG3850	Histidine kinase
GZS08_RS06625	COG0493	'glutamate synthase
GZS08_RS06625	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GZS08_RS06635	COG5342	invasion associated locus B
GZS08_RS06640	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GZS08_RS06645	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GZS08_RS06650	COG0280	phosphate acetyltransferase
GZS08_RS06650	COG0281	malic enzyme
GZS08_RS06655	COG4810	utilization protein
GZS08_RS06660	COG4917	ethanolamine utilization protein
GZS08_RS06665	COG4766	ethanolamine catabolic process
GZS08_RS06670	COG4812	Cobalamin adenosyltransferase
GZS08_RS06675	COG0280	phosphate acetyltransferase
GZS08_RS06680	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
GZS08_RS06685	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
GZS08_RS06690	COG1012	belongs to the aldehyde dehydrogenase family
GZS08_RS06695	COG4820	ethanolamine utilization protein (EutJ)
GZS08_RS06700	COG1454	alcohol dehydrogenase
GZS08_RS06705	COG3192	ethanolamine utilization protein
GZS08_RS06710	COG4819	ethanolamine utilization protein
GZS08_RS06715	COG4303	Ethanolamine ammonia lyase large subunit
GZS08_RS06725	COG4816	utilization protein
GZS08_RS06730	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
GZS08_RS06735	COG2207	Transcriptional regulator
GZS08_RS06745	COG0860	N-Acetylmuramoyl-L-alanine amidase
GZS08_RS06750	COG0456	acetyltransferase
GZS08_RS06765	COG2837	iron assimilation
GZS08_RS06770	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GZS08_RS06775	COG1263	PTS System
GZS08_RS06775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GZS08_RS06790	COG1028	Short-chain dehydrogenase reductase Sdr
GZS08_RS06795	COG4150	thiosulfate binding
GZS08_RS06800	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
GZS08_RS06805	COG4208	sulfate ABC transporter
GZS08_RS06810	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GZS08_RS06815	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GZS08_RS06820	COG4884	unkown
GZS08_RS06820	COG3831	ATPase activity
GZS08_RS06835	COG2190	(PTS) system
GZS08_RS06840	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GZS08_RS06845	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GZS08_RS06850	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GZS08_RS06870	COG3530	Putative quorum-sensing-regulated virulence factor
GZS08_RS06875	COG0385	Bile acid
GZS08_RS06880	COG0583	DNA-binding transcription factor activity
GZS08_RS06890	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GZS08_RS06895	COG2211	Major facilitator Superfamily
GZS08_RS06905	COG0583	DNA-binding transcription factor activity
GZS08_RS06935	COG3415	Transposase
GZS08_RS06940	COG3415	Transposase
GZS08_RS06955	COG2199	diguanylate cyclase activity
GZS08_RS06955	COG2200	EAL domain
GZS08_RS06960	COG3385	transposase activity
GZS08_RS06965	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GZS08_RS06990	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GZS08_RS06995	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GZS08_RS07000	COG0006	proline dipeptidase activity
GZS08_RS07005	COG1363	Peptidase, m42
GZS08_RS07010	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GZS08_RS07010	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GZS08_RS07010	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GZS08_RS07020	COG3279	Response regulator of the LytR AlgR family
GZS08_RS07025	COG3275	phosphorelay sensor kinase activity
GZS08_RS07030	COG0436	Aminotransferase
GZS08_RS07040	COG1560	Kdo2-lipid A biosynthetic process
GZS08_RS07065	COG0028	Belongs to the TPP enzyme family
GZS08_RS07070	COG0679	Auxin Efflux Carrier
GZS08_RS07075	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GZS08_RS07080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GZS08_RS07080	COG2198	Histidine kinase
GZS08_RS07080	COG2205	protein histidine kinase activity
GZS08_RS07080	COG0784	Response regulator, receiver
GZS08_RS07085	COG2197	response regulator
GZS08_RS07090	COG1566	PFAM secretion protein HlyD family protein
GZS08_RS07095	COG0477	Major facilitator Superfamily
GZS08_RS07135	COG2116	formate transmembrane transporter activity
GZS08_RS07140	COG2853	Lipoprotein
GZS08_RS07150	COG3547	Transposase (IS116 IS110 IS902 family)
GZS08_RS07155	COG2067	long-chain fatty acid transport protein
GZS08_RS07160	COG3691	Protein conserved in bacteria
GZS08_RS07175	COG2062	phosphohistidine phosphatase, SixA
GZS08_RS07180	COG3539	Fimbrial protein
GZS08_RS07185	COG3188	usher protein
GZS08_RS07190	COG3121	Chaperone
GZS08_RS07195	COG3539	Fimbrial protein
GZS08_RS07200	COG3539	Fimbrial protein
GZS08_RS07205	COG3539	Fimbrial protein
GZS08_RS07220	COG2890	protein-(glutamine-N5) methyltransferase activity
GZS08_RS07235	COG0730	response to heat
GZS08_RS07240	COG3101	peptidyl-lysine hydroxylation
GZS08_RS07255	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GZS08_RS07260	COG2814	Major facilitator Superfamily
GZS08_RS07275	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GZS08_RS07285	COG0586	Pfam SNARE associated Golgi protein
GZS08_RS07295	COG0285	dihydrofolate synthase activity
GZS08_RS07300	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GZS08_RS07305	COG1286	toxin biosynthetic process
GZS08_RS07310	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GZS08_RS07315	COG0163	prenyltransferase activity
GZS08_RS07320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GZS08_RS07325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GZS08_RS07330	COG4215	(ABC) transporter
GZS08_RS07335	COG4160	amino acid transport
GZS08_RS07340	COG4598	ABC transporter
GZS08_RS07345	COG5464	transposase or invertase
GZS08_RS07350	COG1090	epimerase
GZS08_RS07355	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GZS08_RS07360	COG0625	glutathione transferase activity
GZS08_RS07365	COG0625	glutathione transferase activity
GZS08_RS07370	COG0622	Phosphoesterase
GZS08_RS07375	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GZS08_RS07380	COG1288	antiporter activity
GZS08_RS07385	COG0280	phosphate acetyltransferase
GZS08_RS07385	COG0857	belongs to the CobB CobQ family
GZS08_RS07390	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GZS08_RS07405	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GZS08_RS07410	COG0471	metal ion transport
GZS08_RS07410	COG0490	domain, Protein
GZS08_RS07420	COG0436	Aminotransferase
GZS08_RS07425	COG0583	DNA-binding transcription factor activity
GZS08_RS07445	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
GZS08_RS07450	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GZS08_RS07455	COG1034	ATP synthesis coupled electron transport
GZS08_RS07470	COG0839	Belongs to the complex I subunit 6 family
GZS08_RS07480	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GZS08_RS07485	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GZS08_RS07495	COG0457	Tetratricopeptide repeat
GZS08_RS07515	COG2234	aminopeptidase activity
GZS08_RS07520	COG2304	oxidoreductase activity
GZS08_RS07525	COG5160	protein modification by small protein removal
GZS08_RS07535	COG2153	protein acetylation
GZS08_RS07540	COG4575	ribosome binding
GZS08_RS07545	COG1169	isochorismate synthase
GZS08_RS07560	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GZS08_RS07570	COG0318	PFAM AMP-dependent synthetase and ligase
GZS08_RS07645	COG2271	Major facilitator Superfamily
GZS08_RS07660	COG5464	transposase or invertase
GZS08_RS07665	COG0247	lactate metabolic process
GZS08_RS07675	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GZS08_RS07680	COG2271	Major facilitator Superfamily
GZS08_RS07685	COG0584	glycerophosphoryl diester phosphodiesterase
GZS08_RS07695	COG3642	lipopolysaccharide core region biosynthetic process
GZS08_RS07700	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GZS08_RS07705	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GZS08_RS07710	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GZS08_RS07715	COG3468	outer membrane autotransporter barrel domain protein
GZS08_RS07725	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GZS08_RS07730	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
GZS08_RS07735	COG3234	Protein of unknown function (DUF1175)
GZS08_RS07740	COG2373	Large extracellular alpha-helical protein
GZS08_RS07745	COG5445	Predicted secreted protein (DUF2300)
GZS08_RS07750	COG4676	Protein conserved in bacteria
GZS08_RS07755	COG0183	Belongs to the thiolase family
GZS08_RS07760	COG2031	fatty acid transporter
GZS08_RS07765	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GZS08_RS07770	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GZS08_RS07775	COG2204	response regulator
GZS08_RS07780	COG3852	Histidine kinase
GZS08_RS07785	COG2205	protein histidine kinase activity
GZS08_RS07785	COG0784	Response regulator, receiver
GZS08_RS07790	COG2197	response regulator
GZS08_RS07795	COG0642	Histidine kinase
GZS08_RS07795	COG2198	Histidine kinase
GZS08_RS07800	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GZS08_RS07805	COG1477	protein flavinylation
GZS08_RS07810	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GZS08_RS07810	COG2169	Transcriptional regulator
GZS08_RS07815	COG3145	DNA-N1-methyladenine dioxygenase activity
GZS08_RS07820	COG4615	Cyclic peptide transporter
GZS08_RS07835	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
GZS08_RS07835	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GZS08_RS07840	COG3062	negative regulation of establishment of protein localization
GZS08_RS07850	COG0437	4 iron, 4 sulfur cluster binding
GZS08_RS07855	COG0348	domain, Protein
GZS08_RS07860	COG3043	anaerobic respiration
GZS08_RS07865	COG3005	denitrification pathway
GZS08_RS07870	COG4133	protoheme IX ABC transporter activity
GZS08_RS07875	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GZS08_RS07880	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GZS08_RS07885	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GZS08_RS07895	COG1138	Cytochrome C-type biogenesis protein
GZS08_RS07900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GZS08_RS07905	COG3088	subunit of a heme lyase
GZS08_RS07905	COG4235	cytochrome complex assembly
GZS08_RS07910	COG2197	response regulator
GZS08_RS07915	COG3468	outer membrane autotransporter barrel domain protein
GZS08_RS07925	COG3083	sulfuric ester hydrolase activity
GZS08_RS07945	COG1061	Type III restriction enzyme res subunit
GZS08_RS07950	COG1187	pseudouridine synthase activity
GZS08_RS07955	COG2814	Major facilitator Superfamily
GZS08_RS07965	COG4172	Belongs to the ABC transporter superfamily
GZS08_RS07970	COG4239	(ABC) transporter, permease
GZS08_RS07975	COG4174	ABC transporter (Permease)
GZS08_RS07980	COG4166	transmembrane transport
GZS08_RS07985	COG2200	EAL domain
GZS08_RS07990	COG0791	NLP P60 protein
GZS08_RS07995	COG0671	phosphoesterase, PA-phosphatase related
GZS08_RS08000	COG0523	cobalamin synthesis protein
GZS08_RS08005	COG0246	Mannitol dehydrogenase
GZS08_RS08020	COG2814	Major facilitator Superfamily
GZS08_RS08025	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GZS08_RS08025	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GZS08_RS08030	COG1105	Belongs to the carbohydrate kinase PfkB family
GZS08_RS08035	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GZS08_RS08035	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GZS08_RS08035	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GZS08_RS08040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GZS08_RS08045	COG2313	pseudouridylate synthase activity
GZS08_RS08050	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GZS08_RS08055	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GZS08_RS08065	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GZS08_RS08070	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GZS08_RS08070	COG1522	sequence-specific DNA binding
GZS08_RS08080	COG2855	membrane
GZS08_RS08085	COG0583	DNA-binding transcription factor activity
GZS08_RS08090	COG0833	amino acid
GZS08_RS08110	COG2311	Membrane
GZS08_RS08115	COG1609	Transcriptional regulator
GZS08_RS08120	COG1879	ABC-type sugar transport system periplasmic component
GZS08_RS08125	COG1129	ABC transporter
GZS08_RS08130	COG4211	Belongs to the binding-protein-dependent transport system permease family
GZS08_RS08135	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GZS08_RS08135	COG0167	dihydroorotate dehydrogenase activity
GZS08_RS08140	COG0493	'glutamate synthase
GZS08_RS08150	COG2949	membrane
GZS08_RS08160	COG1346	cytolysis
GZS08_RS08170	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GZS08_RS08185	COG1028	Short-chain dehydrogenase reductase Sdr
GZS08_RS08190	COG0586	Pfam SNARE associated Golgi protein
GZS08_RS08200	COG1686	Belongs to the peptidase S11 family
GZS08_RS08205	COG0277	FAD linked oxidase domain protein
GZS08_RS08210	COG1472	Belongs to the glycosyl hydrolase 3 family
GZS08_RS08215	COG1732	Glycine betaine
GZS08_RS08220	COG1174	glycine betaine transport
GZS08_RS08225	COG1125	glycine betaine transport
GZS08_RS08230	COG1174	glycine betaine transport
GZS08_RS08240	COG0789	Transcriptional regulator
GZS08_RS08245	COG3275	phosphorelay sensor kinase activity
GZS08_RS08250	COG3279	Response regulator of the LytR AlgR family
GZS08_RS08255	COG4807	Protein conserved in bacteria
GZS08_RS08260	COG4808	Protein conserved in bacteria
GZS08_RS08265	COG4715	Zinc finger, swim domain protein
GZS08_RS08270	COG3552	Protein containing von Willebrand factor type A (VWA) domain
GZS08_RS08290	COG3831	ATPase activity
GZS08_RS08295	COG3831	ATPase activity
GZS08_RS08300	COG3831	ATPase activity
GZS08_RS08310	COG0489	protein tyrosine kinase activity
GZS08_RS08320	COG3539	Fimbrial protein
GZS08_RS08325	COG3121	Chaperone
GZS08_RS08330	COG3188	usher protein
GZS08_RS08335	COG3539	Fimbrial protein
GZS08_RS08340	COG5455	response to cobalt ion
GZS08_RS08360	COG0351	phosphomethylpyrimidine kinase
GZS08_RS08365	COG3757	hydrolase, family 25
GZS08_RS08370	COG2188	Transcriptional regulator
GZS08_RS08375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GZS08_RS08380	COG1397	ADP-ribosylglycohydrolase
GZS08_RS08385	COG2211	Major facilitator Superfamily
GZS08_RS08390	COG1830	Aldolase
GZS08_RS08405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GZS08_RS08410	COG3414	Phosphotransferase system galactitol-specific IIB component
GZS08_RS08415	COG3775	system Galactitol-specific IIC component
GZS08_RS08420	COG1063	alcohol dehydrogenase
GZS08_RS08440	COG0826	peptidase U32
GZS08_RS08450	COG0745	RESPONSE REGULATOR receiver
GZS08_RS08455	COG2205	protein histidine kinase activity
GZS08_RS08495	COG4245	von Willebrand factor, type A
GZS08_RS08505	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
GZS08_RS08510	COG0443	Heat shock 70 kDa protein
GZS08_RS08515	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GZS08_RS08525	COG3547	Transposase (IS116 IS110 IS902 family)
GZS08_RS08535	COG0572	uridine kinase
GZS08_RS08545	COG2982	Protein involved in outer membrane biogenesis
GZS08_RS08565	COG2826	transposase and inactivated derivatives, IS30 family
GZS08_RS08610	COG5039	Polysaccharide pyruvyl transferase
GZS08_RS08690	COG0140	phosphoribosyl-ATP diphosphatase activity
GZS08_RS08690	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GZS08_RS08705	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GZS08_RS08710	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GZS08_RS08710	COG0131	Imidazoleglycerol-phosphate dehydratase
GZS08_RS08735	COG2161	toxin-antitoxin pair type II binding
GZS08_RS08740	COG4115	mRNA cleavage
GZS08_RS08745	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GZS08_RS08750	COG0583	DNA-binding transcription factor activity
GZS08_RS08760	COG0531	amino acid
GZS08_RS08765	COG2391	methyltransferase activity
GZS08_RS08770	COG0425	Belongs to the sulfur carrier protein TusA family
GZS08_RS08775	COG2925	Exonuclease
GZS08_RS08780	COG1686	Belongs to the peptidase S11 family
GZS08_RS08795	COG1289	transmembrane transporter activity
GZS08_RS08825	COG3436	PFAM IS66 Orf2 family protein
GZS08_RS08830	COG4372	Transposase
GZS08_RS08860	COG2003	Belongs to the UPF0758 family
GZS08_RS08880	COG3468	outer membrane autotransporter barrel domain protein
GZS08_RS08885	COG4584	PFAM Integrase catalytic
GZS08_RS08890	COG1484	DNA-dependent DNA replication
GZS08_RS08955	COG2826	transposase and inactivated derivatives, IS30 family
GZS08_RS08965	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
GZS08_RS08980	COG1376	ErfK ybiS ycfS ynhG family protein
GZS08_RS09015	COG2916	Histone family protein nucleoid-structuring protein H-NS
GZS08_RS09115	COG0582	viral genome integration into host DNA
GZS08_RS09125	COG0583	DNA-binding transcription factor activity
GZS08_RS09130	COG0583	DNA-binding transcription factor activity
GZS08_RS09155	COG0217	transcriptional regulatory protein
GZS08_RS09160	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GZS08_RS09165	COG0477	Major facilitator Superfamily
GZS08_RS09175	COG1470	cell adhesion involved in biofilm formation
GZS08_RS09175	COG1388	LysM domain
GZS08_RS09200	COG3443	Belongs to the bacterial solute-binding protein 9 family
GZS08_RS09215	COG2351	hydroxyisourate hydrolase activity
GZS08_RS09220	COG0745	RESPONSE REGULATOR receiver
GZS08_RS09225	COG2205	protein histidine kinase activity
GZS08_RS09240	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GZS08_RS09250	COG1418	mRNA catabolic process
GZS08_RS09255	COG0270	DNA (cytosine-5-)-methyltransferase activity
GZS08_RS09260	COG3727	T/G mismatch-specific endonuclease activity
GZS08_RS09265	COG0697	spore germination
GZS08_RS09270	COG2354	Protein conserved in bacteria
GZS08_RS09275	COG5475	Uncharacterized small protein (DUF2158)
GZS08_RS09300	COG2197	response regulator
GZS08_RS09305	COG1684	flagellar biosynthetic protein fliR
GZS08_RS09310	COG1987	bacterial-type flagellum assembly
GZS08_RS09315	COG1338	Plays a role in the flagellum-specific transport system
GZS08_RS09320	COG3190	flagellar
GZS08_RS09325	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GZS08_RS09330	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GZS08_RS09335	COG1580	Controls the rotational direction of flagella during chemotaxis
GZS08_RS09340	COG3144	bacterial-type flagellum assembly
GZS08_RS09345	COG2882	bacterial-type flagellum organization
GZS08_RS09355	COG1317	bacterial-type flagellum organization
GZS08_RS09360	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GZS08_RS09365	COG1766	The M ring may be actively involved in energy transduction
GZS08_RS09385	COG2135	peptidase activity
GZS08_RS09390	COG0425	Belongs to the sulfur carrier protein TusA family
GZS08_RS09395	COG2391	methyltransferase activity
GZS08_RS09405	COG0366	Alpha amylase catalytic
GZS08_RS09415	COG1516	flagellar protein fliS
GZS08_RS09420	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GZS08_RS09430	COG1191	sigma factor activity
GZS08_RS09440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GZS08_RS09450	COG0765	amino acid transport
GZS08_RS09455	COG1126	abc transporter atp-binding protein
GZS08_RS09460	COG2197	response regulator
GZS08_RS09475	COG2197	response regulator
GZS08_RS09505	COG3012	SEC-C Motif Domain Protein
GZS08_RS09505	COG3318	Belongs to the UPF0149 family
GZS08_RS09510	COG0814	amino acid
GZS08_RS09520	COG1528	Iron-storage protein
GZS08_RS09540	COG1528	Iron-storage protein
GZS08_RS09545	COG1879	ABC-type sugar transport system periplasmic component
GZS08_RS09550	COG1129	ABC transporter
GZS08_RS09555	COG1172	Belongs to the binding-protein-dependent transport system permease family
GZS08_RS09560	COG1877	trehalose-phosphatase activity
GZS08_RS09570	COG0589	response to stress
GZS08_RS09585	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GZS08_RS09590	COG1360	Flagellar Motor Protein
GZS08_RS09595	COG2198	Histidine kinase
GZS08_RS09595	COG0643	Histidine kinase
GZS08_RS09600	COG0835	chemotaxis
GZS08_RS09605	COG0840	transmembrane signaling receptor activity
GZS08_RS09610	COG0840	transmembrane signaling receptor activity
GZS08_RS09615	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GZS08_RS09620	COG2201	protein-glutamate methylesterase activity
GZS08_RS09625	COG0745	RESPONSE REGULATOR receiver
GZS08_RS09630	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GZS08_RS09635	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GZS08_RS09650	COG3755	Protein conserved in bacteria
GZS08_RS09660	COG3102	Protein conserved in bacteria
GZS08_RS09670	COG3005	denitrification pathway
GZS08_RS09675	COG0243	molybdopterin cofactor binding
GZS08_RS09690	COG3788	relative of glutathione S-transferase, MAPEG superfamily
GZS08_RS09695	COG1801	Protein of unknown function DUF72
GZS08_RS09700	COG1335	isochorismatase
GZS08_RS09710	COG0494	nUDIX hydrolase
GZS08_RS09715	COG0217	transcriptional regulatory protein
GZS08_RS09745	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GZS08_RS09755	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GZS08_RS09760	COG0739	heme binding
GZS08_RS09765	COG1560	Kdo2-lipid A biosynthetic process
GZS08_RS09770	COG0469	pyruvate kinase activity
GZS08_RS09775	COG1737	Transcriptional regulator
GZS08_RS09780	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GZS08_RS09785	COG0129	dihydroxy-acid dehydratase activity
GZS08_RS09790	COG0800	Aldolase
GZS08_RS09800	COG3141	response to X-ray
GZS08_RS09810	COG2979	Protein of unknown function (DUF533)
GZS08_RS09815	COG1770	oligopeptidase
GZS08_RS09820	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GZS08_RS09825	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GZS08_RS09835	COG2372	response to copper ion
GZS08_RS09840	COG1276	copper resistance
GZS08_RS09850	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GZS08_RS09870	COG3008	intermembrane lipid transfer
GZS08_RS09875	COG2995	paraquat-inducible protein a
GZS08_RS09880	COG1956	GAF domain-containing protein
GZS08_RS09890	COG0793	Belongs to the peptidase S41A family
GZS08_RS09900	COG2814	Major facilitator Superfamily
GZS08_RS09905	COG1414	Transcriptional regulator
GZS08_RS09935	COG2226	methyltransferase
GZS08_RS09950	COG3716	PTS system mannose fructose sorbose family IID component
GZS08_RS09955	COG3715	PTS system
GZS08_RS09960	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GZS08_RS09960	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GZS08_RS09965	COG1253	flavin adenine dinucleotide binding
GZS08_RS09975	COG1760	l-serine dehydratase
GZS08_RS09985	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GZS08_RS10000	COG0251	oxidation-reduction process
GZS08_RS10005	COG1199	ATP-dependent helicase activity
GZS08_RS10010	COG1214	PFAM Peptidase M22, glycoprotease
GZS08_RS10015	COG3065	identical protein binding
GZS08_RS10020	COG0318	PFAM AMP-dependent synthetase and ligase
GZS08_RS10025	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GZS08_RS10030	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GZS08_RS10035	COG4638	Rieske (2fe-2S)
GZS08_RS10045	COG0473	3-isopropylmalate dehydrogenase activity
GZS08_RS10050	COG0583	DNA-binding transcription factor activity
GZS08_RS10060	COG3615	Tellurite resistance protein tehB
GZS08_RS10065	COG3385	transposase activity
GZS08_RS10080	COG2261	transglycosylase associated protein
GZS08_RS10095	COG2199	diguanylate cyclase activity
GZS08_RS10095	COG2203	Gaf domain
GZS08_RS10100	COG3042	response to heat
GZS08_RS10105	COG3189	MarR family transcriptional regulator
GZS08_RS10110	COG2807	transmembrane transport
GZS08_RS10115	COG2207	Transcriptional regulator
GZS08_RS10130	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GZS08_RS10135	COG2199	diguanylate cyclase activity
GZS08_RS10140	COG2199	diguanylate cyclase activity
GZS08_RS10150	COG2766	serine protein kinase
GZS08_RS10155	COG3713	MltA-interacting MipA family protein
GZS08_RS10160	COG0656	L-ascorbic acid biosynthetic process
GZS08_RS10165	COG0676	glucose-6-phosphate 1-epimerase activity
GZS08_RS10170	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GZS08_RS10180	COG3139	Protein of unknown function (DUF1315)
GZS08_RS10185	COG1063	alcohol dehydrogenase
GZS08_RS10190	COG2271	Major facilitator Superfamily
GZS08_RS10195	COG1063	alcohol dehydrogenase
GZS08_RS10200	COG0191	fructose-bisphosphate aldolase activity
GZS08_RS10205	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GZS08_RS10210	COG0667	Aldo Keto reductase
GZS08_RS10215	COG1349	DNA-binding transcription factor activity
GZS08_RS10220	COG2814	Major facilitator Superfamily
GZS08_RS10225	COG1335	isochorismatase
GZS08_RS10230	COG0252	asparaginase activity
GZS08_RS10235	COG0616	signal peptide processing
GZS08_RS10240	COG0778	Nitroreductase
GZS08_RS10250	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GZS08_RS10260	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GZS08_RS10270	COG0494	nUDIX hydrolase
GZS08_RS10275	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GZS08_RS10280	COG2897	thiosulfate sulfurtransferase activity
GZS08_RS10285	COG4136	ATPase activity
GZS08_RS10290	COG4135	transport system, permease component
GZS08_RS10295	COG4134	Bacterial extracellular solute-binding protein
GZS08_RS10300	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GZS08_RS10305	COG0398	Pfam SNARE associated Golgi protein
GZS08_RS10315	COG0398	Pfam SNARE associated Golgi protein
GZS08_RS10320	COG0708	Exodeoxyribonuclease III
GZS08_RS10350	COG3678	ATP-independent chaperone mediated protein folding
GZS08_RS10360	COG0322	excinuclease ABC activity
GZS08_RS10370	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GZS08_RS10375	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GZS08_RS10380	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GZS08_RS10385	COG1447	Phosphotransferase system cellobiose-specific component IIA
GZS08_RS10390	COG1917	Cupin 2, conserved barrel domain protein
GZS08_RS10390	COG2169	Transcriptional regulator
GZS08_RS10395	COG1486	melibiose metabolic process
GZS08_RS10405	COG0753	catalase activity
GZS08_RS10420	COG1823	symporter activity
GZS08_RS10425	COG1988	membrane-bound metal-dependent
GZS08_RS10430	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GZS08_RS10440	COG3001	Fructosamine kinase
GZS08_RS10450	COG1105	Belongs to the carbohydrate kinase PfkB family
GZS08_RS10455	COG3137	Salt-induced outer membrane protein
GZS08_RS10500	COG0072	phenylalanine-tRNA ligase activity
GZS08_RS10500	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GZS08_RS10515	COG0386	Belongs to the glutathione peroxidase family
GZS08_RS10525	COG0791	NLP P60 protein
GZS08_RS10530	COG2200	EAL domain
GZS08_RS10540	COG4256	Hemin uptake protein
GZS08_RS10545	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GZS08_RS10555	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GZS08_RS10555	COG0574	Belongs to the PEP-utilizing enzyme family
GZS08_RS10560	COG0318	PFAM AMP-dependent synthetase and ligase
GZS08_RS10565	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
GZS08_RS10570	COG0644	oxidoreductase
GZS08_RS10575	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GZS08_RS10580	COG2086	electron transfer activity
GZS08_RS10585	COG1917	Cupin 2, conserved barrel domain protein
GZS08_RS10585	COG2207	Transcriptional regulator
GZS08_RS10590	COG1960	acyl-CoA dehydrogenase activity
GZS08_RS10595	COG4670	ketone body catabolic process
GZS08_RS10610	COG2271	Major facilitator Superfamily
GZS08_RS10615	COG0738	Major facilitator superfamily
GZS08_RS10630	COG0628	permease
GZS08_RS10635	COG0247	lactate metabolic process
GZS08_RS10635	COG0277	FAD linked oxidase domain protein
GZS08_RS10640	COG2050	protein possibly involved in aromatic compounds catabolism
GZS08_RS10650	COG0316	Belongs to the HesB IscA family
GZS08_RS10655	COG0719	Fe-S assembly protein
GZS08_RS10660	COG0396	ATPase activity
GZS08_RS10690	COG1376	ErfK ybiS ycfS ynhG family protein
GZS08_RS10695	COG4238	major outer membrane lipoprotein
GZS08_RS10700	COG0469	pyruvate kinase activity
GZS08_RS10710	COG0437	4 iron, 4 sulfur cluster binding
GZS08_RS10715	COG2414	aldehyde ferredoxin oxidoreductase
GZS08_RS10725	COG0437	4 iron, 4 sulfur cluster binding
GZS08_RS10730	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
GZS08_RS10740	COG4529	Protein conserved in bacteria
GZS08_RS10760	COG3468	outer membrane autotransporter barrel domain protein
GZS08_RS10770	COG0307	riboflavin synthase, alpha
GZS08_RS10775	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GZS08_RS10780	COG2814	Major facilitator Superfamily
GZS08_RS10785	COG0583	DNA-binding transcription factor activity
GZS08_RS10800	COG2814	Major facilitator Superfamily
GZS08_RS10805	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GZS08_RS10810	COG0791	NLP P60 protein
GZS08_RS10815	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GZS08_RS10820	COG1201	RNA secondary structure unwinding
GZS08_RS10825	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GZS08_RS10830	COG0346	lactoylglutathione lyase activity
GZS08_RS10835	COG1902	pentaerythritol trinitrate reductase activity
GZS08_RS10840	COG1309	transcriptional regulator
GZS08_RS10845	COG3313	Fe-S protein
GZS08_RS10850	COG4989	oxidoreductase activity
GZS08_RS10855	COG2032	superoxide dismutase activity
GZS08_RS10860	COG1289	transmembrane transporter activity
GZS08_RS10865	COG1566	PFAM secretion protein HlyD family protein
GZS08_RS10880	COG3133	Outer membrane lipoprotein
GZS08_RS10890	COG3895	Periplasmic Protein
GZS08_RS10905	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
GZS08_RS10910	COG0625	glutathione transferase activity
GZS08_RS10915	COG3104	oligopeptide transport
GZS08_RS10920	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GZS08_RS10930	COG4659	FMN binding
GZS08_RS10970	COG0673	inositol 2-dehydrogenase activity
GZS08_RS10980	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GZS08_RS10985	COG1263	PTS System
GZS08_RS10985	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GZS08_RS10990	COG1609	Transcriptional regulator
GZS08_RS10995	COG1028	Short-chain dehydrogenase reductase Sdr
GZS08_RS11000	COG1309	transcriptional regulator
GZS08_RS11005	COG3250	beta-galactosidase activity
GZS08_RS11020	COG5339	Protein conserved in bacteria
GZS08_RS11025	COG1482	cell wall glycoprotein biosynthetic process
GZS08_RS11030	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GZS08_RS11030	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GZS08_RS11035	COG0114	fumarate hydratase activity
GZS08_RS11045	COG2205	protein histidine kinase activity
GZS08_RS11050	COG0745	RESPONSE REGULATOR receiver
GZS08_RS11055	COG3136	membrane protein required for alginate biosynthesis
GZS08_RS11065	COG0531	amino acid
GZS08_RS11075	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GZS08_RS11080	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GZS08_RS11085	COG0628	permease
GZS08_RS11100	COG3591	Belongs to the peptidase S1B family
GZS08_RS11115	COG2814	Major facilitator Superfamily
GZS08_RS11120	COG0583	DNA-binding transcription factor activity
GZS08_RS11125	COG1940	carbohydrate kinase activity
GZS08_RS11130	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GZS08_RS11140	COG3381	protein complex oligomerization
GZS08_RS11145	COG3302	dmso reductase anchor subunit
GZS08_RS11150	COG0437	4 iron, 4 sulfur cluster binding
GZS08_RS11155	COG0243	molybdopterin cofactor binding
GZS08_RS11160	COG0243	molybdopterin cofactor binding
GZS08_RS11175	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GZS08_RS11190	COG4948	Mandelate Racemase Muconate Lactonizing
GZS08_RS11195	COG1063	alcohol dehydrogenase
GZS08_RS11200	COG0477	Major facilitator Superfamily
GZS08_RS11205	COG0246	Mannitol dehydrogenase
GZS08_RS11215	COG1802	Transcriptional regulator
GZS08_RS11220	COG4221	oxidoreductase activity
GZS08_RS11225	COG0339	signal peptide processing
GZS08_RS11230	COG1546	Belongs to the CinA family
GZS08_RS11235	COG3111	PFAM Bacterial OB fold (BOF) protein
GZS08_RS11240	COG3706	GGDEF domain
GZS08_RS11250	COG2814	Major facilitator Superfamily
GZS08_RS11265	COG4977	sequence-specific DNA binding
GZS08_RS11270	COG1846	Transcriptional regulator
GZS08_RS11290	COG0583	DNA-binding transcription factor activity
GZS08_RS11295	COG1012	belongs to the aldehyde dehydrogenase family
GZS08_RS11300	COG2066	Belongs to the glutaminase family
GZS08_RS11320	COG3781	membrane
GZS08_RS11370	COG2911	Protein conserved in bacteria
GZS08_RS11370	COG3210	domain, Protein
GZS08_RS11375	COG1396	sequence-specific DNA binding
GZS08_RS11380	COG3550	peptidyl-serine autophosphorylation
GZS08_RS11395	COG3539	Fimbrial protein
GZS08_RS11400	COG3539	Fimbrial protein
GZS08_RS11405	COG3539	Fimbrial protein
GZS08_RS11410	COG0243	molybdopterin cofactor binding
GZS08_RS11420	COG2207	Transcriptional regulator
GZS08_RS11425	COG3119	arylsulfatase activity
GZS08_RS11430	COG0641	radical SAM
GZS08_RS11440	COG4178	(ABC) transporter
GZS08_RS11445	COG4771	TonB-dependent receptor
GZS08_RS11450	COG0612	Peptidase, M16
GZS08_RS11455	COG0076	glutamate decarboxylase activity
GZS08_RS11460	COG0531	amino acid
GZS08_RS11465	COG1649	PFAM Uncharacterised BCR, COG1649
GZS08_RS11470	COG3706	GGDEF domain
GZS08_RS11475	COG2200	EAL domain
GZS08_RS11475	COG2199	diguanylate cyclase activity
GZS08_RS11475	COG2202	Pas domain
GZS08_RS11480	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
GZS08_RS11485	COG0747	negative chemotaxis
GZS08_RS11490	COG0601	transmembrane transport
GZS08_RS11495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GZS08_RS11500	COG0444	Belongs to the ABC transporter superfamily
GZS08_RS11505	COG4608	Belongs to the ABC transporter superfamily
GZS08_RS11510	COG1764	response to oxidative stress
GZS08_RS11530	COG1064	alcohol dehydrogenase
GZS08_RS11535	COG3093	addiction module antidote protein HigA
GZS08_RS11540	COG2864	formate dehydrogenase
GZS08_RS11545	COG0437	4 iron, 4 sulfur cluster binding
GZS08_RS11555	COG0697	spore germination
GZS08_RS11560	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GZS08_RS11570	COG2223	nitrite transmembrane transporter activity
GZS08_RS11580	COG1140	nitrate reductase beta subunit
GZS08_RS11585	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GZS08_RS11590	COG2181	nitrate reductase activity
GZS08_RS11595	COG0384	phenazine biosynthesis protein PhzF
GZS08_RS11600	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GZS08_RS11605	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GZS08_RS11615	COG5433	transposase activity
GZS08_RS11635	COG3209	COG3209 Rhs family protein
GZS08_RS11650	COG0625	glutathione transferase activity
GZS08_RS11655	COG1113	amino acid transport
GZS08_RS11660	COG3391	amine dehydrogenase activity
GZS08_RS11665	COG4772	TonB-dependent receptor
GZS08_RS11670	COG1802	Transcriptional regulator
GZS08_RS11675	COG2130	NADP-dependent
GZS08_RS11680	COG1247	-acetyltransferase
GZS08_RS11685	COG3238	Protein conserved in bacteria
GZS08_RS11710	COG1177	transmembrane transport
GZS08_RS11715	COG1176	ABC-type spermidine putrescine transport system, permease component I
GZS08_RS11720	COG3842	ATPase activity
GZS08_RS11725	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GZS08_RS11730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GZS08_RS11735	COG1598	PFAM Uncharacterised protein family UPF0150
GZS08_RS11740	COG1724	mRNA binding
GZS08_RS11750	COG0826	peptidase U32
GZS08_RS11755	COG1396	sequence-specific DNA binding
GZS08_RS11760	COG3135	benzoate transporter
GZS08_RS11765	COG0675	Transposase, IS605 OrfB family
GZS08_RS11780	COG0500	methyltransferase
GZS08_RS11785	COG1275	C4-dicarboxylate transporter malic acid transport protein
GZS08_RS11790	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GZS08_RS11795	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GZS08_RS11800	COG2841	Protein conserved in bacteria
GZS08_RS11810	COG5383	Protein conserved in bacteria
GZS08_RS11815	COG0583	DNA-binding transcription factor activity
GZS08_RS11820	COG0840	transmembrane signaling receptor activity
GZS08_RS11835	COG3038	cytochrome b561
GZS08_RS11845	COG1012	belongs to the aldehyde dehydrogenase family
GZS08_RS11850	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GZS08_RS11855	COG1643	Atp-dependent helicase
GZS08_RS11865	COG0671	phosphoesterase, PA-phosphatase related
GZS08_RS11865	COG2453	phosphatase
GZS08_RS11870	COG2267	carboxylic ester hydrolase activity
GZS08_RS11875	COG4589	Belongs to the CDS family
GZS08_RS11880	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GZS08_RS11890	COG0667	Aldo Keto reductase
GZS08_RS11915	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GZS08_RS11920	COG3327	negative regulation of DNA-templated transcription, initiation
GZS08_RS11925	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
GZS08_RS11930	COG0183	Belongs to the thiolase family
GZS08_RS11935	COG2050	protein possibly involved in aromatic compounds catabolism
GZS08_RS11940	COG1250	3-hydroxyacyl-CoA dehydrogenase
GZS08_RS11945	COG1024	Enoyl-CoA hydratase
GZS08_RS11950	COG1024	Enoyl-CoA hydratase
GZS08_RS11955	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GZS08_RS11960	COG2151	metal-sulfur cluster biosynthetic enzyme
GZS08_RS11965	COG3396	Phenylacetate-CoA oxygenase
GZS08_RS11970	COG3460	Phenylacetate-CoA oxygenase
GZS08_RS11975	COG3396	Phenylacetate-CoA oxygenase
GZS08_RS11980	COG1012	belongs to the aldehyde dehydrogenase family
GZS08_RS11980	COG2030	dehydratase
GZS08_RS11985	COG3733	amine oxidase
GZS08_RS11990	COG1012	belongs to the aldehyde dehydrogenase family
GZS08_RS11995	COG2207	Transcriptional regulator
GZS08_RS12000	COG3784	Protein of unknown function (DUF1318)
GZS08_RS12010	COG2911	Protein conserved in bacteria
GZS08_RS12015	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GZS08_RS12020	COG3187	Heat shock protein
GZS08_RS12025	COG3042	response to heat
GZS08_RS12030	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GZS08_RS12030	COG0674	pyruvate-flavodoxin oxidoreductase activity
GZS08_RS12030	COG1013	pyruvate-flavodoxin oxidoreductase activity
GZS08_RS12030	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GZS08_RS12035	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GZS08_RS12040	COG0589	response to stress
GZS08_RS12050	COG0513	Belongs to the DEAD box helicase family
GZS08_RS12060	COG3706	GGDEF domain
GZS08_RS12065	COG2840	Smr protein MutS2
GZS08_RS12070	COG0583	DNA-binding transcription factor activity
GZS08_RS12075	COG1473	amidohydrolase
GZS08_RS12080	COG1473	amidohydrolase
GZS08_RS12085	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GZS08_RS12090	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GZS08_RS12095	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GZS08_RS12100	COG0589	response to stress
GZS08_RS12105	COG3182	Iron-regulated membrane protein
GZS08_RS12110	COG0668	transmembrane transport
GZS08_RS12115	COG4166	transmembrane transport
GZS08_RS12120	COG0583	DNA-binding transcription factor activity
GZS08_RS12125	COG1073	alpha beta
GZS08_RS12140	COG2866	Carboxypeptidase
GZS08_RS12145	COG4948	Mandelate Racemase Muconate Lactonizing
GZS08_RS12150	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GZS08_RS12155	COG3283	Transcriptional regulator of aromatic amino acids metabolism
GZS08_RS12165	COG3106	COG3106 Predicted ATPase
GZS08_RS12170	COG1609	Transcriptional regulator
GZS08_RS12180	COG3842	ATPase activity
GZS08_RS12185	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GZS08_RS12190	COG1554	hydrolase, family 65, central catalytic
GZS08_RS12195	COG0673	inositol 2-dehydrogenase activity
GZS08_RS12200	COG1082	Xylose isomerase domain protein TIM barrel
GZS08_RS12205	COG1063	alcohol dehydrogenase
GZS08_RS12210	COG0395	ABC-type sugar transport system, permease component
GZS08_RS12215	COG1175	transmembrane transport
GZS08_RS12225	COG0366	Alpha amylase catalytic
GZS08_RS12230	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GZS08_RS12240	COG1983	PspC domain protein
GZS08_RS12250	COG1842	Phage shock protein A
GZS08_RS12255	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GZS08_RS12260	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GZS08_RS12265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GZS08_RS12270	COG1012	belongs to the aldehyde dehydrogenase family
GZS08_RS12275	COG1917	Cupin 2, conserved barrel domain protein
GZS08_RS12275	COG1396	sequence-specific DNA binding
GZS08_RS12280	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GZS08_RS12285	COG0174	glutamine synthetase
GZS08_RS12295	COG0531	amino acid
GZS08_RS12305	COG4166	transmembrane transport
GZS08_RS12310	COG4168	peptide transport system, permease
GZS08_RS12315	COG4171	peptide transport system, permease
GZS08_RS12320	COG4172	Belongs to the ABC transporter superfamily
GZS08_RS12325	COG4172	Belongs to the ABC transporter superfamily
GZS08_RS12330	COG2852	Protein conserved in bacteria
GZS08_RS12335	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GZS08_RS12340	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GZS08_RS12340	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GZS08_RS12355	COG5001	Diguanylate cyclase
GZS08_RS12365	COG1349	DNA-binding transcription factor activity
GZS08_RS12375	COG0023	Translation Initiation Factor
GZS08_RS12385	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GZS08_RS12390	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
GZS08_RS12395	COG0671	phosphoesterase, PA-phosphatase related
GZS08_RS12405	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GZS08_RS12430	COG0583	DNA-binding transcription factor activity
GZS08_RS12435	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GZS08_RS12445	COG0616	signal peptide processing
GZS08_RS12450	COG1028	Short-chain dehydrogenase reductase Sdr
GZS08_RS12455	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GZS08_RS12460	COG1187	pseudouridine synthase activity
GZS08_RS12465	COG4907	membrane protein (DUF2207)
GZS08_RS12470	COG0009	L-threonylcarbamoyladenylate synthase
GZS08_RS12475	COG0613	PHP domain protein
GZS08_RS12485	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GZS08_RS12490	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GZS08_RS12490	COG0512	Glutamine amidotransferase of anthranilate synthase
GZS08_RS12495	COG0135	phosphoribosylanthranilate isomerase activity
GZS08_RS12495	COG0134	indole-3-glycerol-phosphate synthase activity
GZS08_RS12510	COG3729	General stress protein
GZS08_RS12515	COG3685	Protein conserved in bacteria
GZS08_RS12520	COG3685	Protein conserved in bacteria
GZS08_RS12525	COG3047	cAMP biosynthetic process
GZS08_RS12545	COG1607	acyl-coa hydrolase
GZS08_RS12550	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GZS08_RS12555	COG2350	Protein conserved in bacteria
GZS08_RS12560	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GZS08_RS12580	COG4608	Belongs to the ABC transporter superfamily
GZS08_RS12585	COG0444	Belongs to the ABC transporter superfamily
GZS08_RS12590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GZS08_RS12595	COG0601	transmembrane transport
GZS08_RS12600	COG4166	transmembrane transport
GZS08_RS12605	COG2095	MarC family integral membrane protein
GZS08_RS12610	COG1012	belongs to the aldehyde dehydrogenase family
GZS08_RS12610	COG1454	alcohol dehydrogenase
GZS08_RS12620	COG1435	thymidine kinase activity
GZS08_RS12630	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GZS08_RS12635	COG0745	RESPONSE REGULATOR receiver
GZS08_RS12640	COG1752	Esterase of the alpha-beta hydrolase superfamily
GZS08_RS12650	COG0788	formyltetrahydrofolate deformylase activity
GZS08_RS12685	COG2181	nitrate reductase activity
GZS08_RS12690	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GZS08_RS12695	COG1140	nitrate reductase beta subunit
GZS08_RS12700	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GZS08_RS12705	COG2223	nitrite transmembrane transporter activity
GZS08_RS12710	COG3850	Histidine kinase
GZS08_RS12715	COG2197	response regulator
GZS08_RS12720	COG4932	domain protein
GZS08_RS12725	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GZS08_RS12730	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
GZS08_RS12735	COG4572	Cation transport regulator
GZS08_RS12740	COG0387	Pfam Sodium calcium exchanger
GZS08_RS12765	COG2912	Transglutaminase-like superfamily
GZS08_RS12770	COG3094	Invasion gene expression up-regulator, SirB
GZS08_RS12775	COG2890	protein-(glutamine-N5) methyltransferase activity
GZS08_RS12800	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GZS08_RS12805	COG0659	secondary active sulfate transmembrane transporter activity
GZS08_RS12820	COG0012	GTP binding
GZS08_RS12825	COG3468	outer membrane autotransporter barrel domain protein
GZS08_RS12830	COG3284	Transcriptional regulator
GZS08_RS12835	COG2376	Dihydroxyacetone kinase
GZS08_RS12840	COG1461	Dihydroxyacetone kinase
GZS08_RS12845	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
GZS08_RS12845	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GZS08_RS12845	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GZS08_RS12860	COG2261	transglycosylase associated protein
GZS08_RS12865	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
GZS08_RS12875	COG1619	proteins homologs of microcin C7 resistance protein MccF
GZS08_RS12885	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GZS08_RS12895	COG2719	SpoVR family
GZS08_RS12910	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GZS08_RS12915	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GZS08_RS12920	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GZS08_RS12935	COG0179	Fumarylacetoacetate (FAA) hydrolase
GZS08_RS12960	COG2894	cell division
GZS08_RS13035	COG2200	EAL domain
GZS08_RS13040	COG0789	Transcriptional regulator
GZS08_RS13045	COG5562	phage envelope protein
GZS08_RS13060	COG0538	isocitrate dehydrogenase activity
GZS08_RS13065	COG1187	pseudouridine synthase activity
GZS08_RS13085	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GZS08_RS13090	COG0745	RESPONSE REGULATOR receiver
GZS08_RS13095	COG2205	protein histidine kinase activity
GZS08_RS13100	COG2850	peptidyl-arginine hydroxylation
GZS08_RS13110	COG3842	ATPase activity
GZS08_RS13125	COG0500	methyltransferase
GZS08_RS13145	COG3344	reverse transcriptase
GZS08_RS13280	COG3772	lysozyme
GZS08_RS13325	COG0484	heat shock protein binding
GZS08_RS13330	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
GZS08_RS13335	COG1403	HNH endonuclease
GZS08_RS13420	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GZS08_RS13430	COG0582	viral genome integration into host DNA
GZS08_RS13435	COG1177	transmembrane transport
GZS08_RS13440	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GZS08_RS13450	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GZS08_RS13455	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GZS08_RS13465	COG4591	ABC-type transport system involved in lipoprotein release permease component
GZS08_RS13470	COG1136	(ABC) transporter
GZS08_RS13475	COG4591	ABC-type transport system involved in lipoprotein release permease component
GZS08_RS13480	COG4763	Acyl-transferase
GZS08_RS13485	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GZS08_RS13490	COG1388	LysM domain
GZS08_RS13490	COG1376	ErfK ybiS ycfS ynhG family protein
GZS08_RS13500	COG1309	transcriptional regulator
GZS08_RS13505	COG3134	Outer membrane lipoprotein
GZS08_RS13510	COG1252	NADH dehydrogenase
GZS08_RS13530	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
GZS08_RS13535	COG5633	Lipoprotein
GZS08_RS13540	COG0537	adenosine 5'-monophosphoramidase activity
GZS08_RS13545	COG4773	Receptor
GZS08_RS13550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GZS08_RS13550	COG1263	PTS System
GZS08_RS13555	COG0084	hydrolase, TatD family'
GZS08_RS13560	COG0470	DNA polymerase III
GZS08_RS13570	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GZS08_RS13575	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GZS08_RS13580	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GZS08_RS13590	COG1028	Short-chain dehydrogenase reductase Sdr
GZS08_RS13595	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GZS08_RS13615	COG1399	metal-binding, possibly nucleic acid-binding protein
GZS08_RS13620	COG0424	maF-like protein
GZS08_RS13625	COG0564	pseudouridine synthase activity
GZS08_RS13635	COG1530	ribonuclease E activity
GZS08_RS13640	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GZS08_RS13645	COG1256	bacterial-type flagellum assembly
GZS08_RS13650	COG1705	Flagellar rod assembly protein muramidase FlgJ
GZS08_RS13650	COG3951	Flagellar rod assembly protein muramidase FlgJ
GZS08_RS13665	COG4786	Flagellar basal body rod
GZS08_RS13670	COG4787	bacterial-type flagellum-dependent cell motility
GZS08_RS13685	COG1815	bacterial-type flagellum-dependent cell motility
GZS08_RS13690	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
GZS08_RS13695	COG2747	anti-sigma28 factor FlgM
GZS08_RS13700	COG3418	PFAM FlgN family protein
GZS08_RS13705	COG0728	peptidoglycan biosynthetic process
GZS08_RS13710	COG0673	inositol 2-dehydrogenase activity
GZS08_RS13720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GZS08_RS13730	COG2999	glutathione oxidoreductase activity
GZS08_RS13765	COG3038	cytochrome b561
GZS08_RS13770	COG2353	YceI-like domain
GZS08_RS13780	COG1560	Kdo2-lipid A biosynthetic process
GZS08_RS13795	COG5645	(Lipo)protein
GZS08_RS13800	COG2943	transferase activity, transferring hexosyl groups
GZS08_RS13815	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GZS08_RS13820	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
GZS08_RS13845	COG2197	response regulator
GZS08_RS13860	COG1462	curli production assembly transport component CsgG
GZS08_RS13870	COG3381	protein complex oligomerization
GZS08_RS13910	COG3706	GGDEF domain
GZS08_RS13915	COG0457	Tetratricopeptide repeat
GZS08_RS13920	COG0726	polysaccharide deacetylase
GZS08_RS13920	COG1649	PFAM Uncharacterised BCR, COG1649
GZS08_RS13925	COG1215	transferase activity, transferring glycosyl groups
GZS08_RS13930	COG3658	cytochrome
GZS08_RS13935	COG1702	phosphate starvation-inducible protein PhoH
GZS08_RS13940	COG2837	iron assimilation
GZS08_RS13945	COG2822	iron ion transport
GZS08_RS13955	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GZS08_RS13965	COG0506	proline dehydrogenase activity
GZS08_RS13965	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GZS08_RS13965	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GZS08_RS13970	COG1309	transcriptional regulator
GZS08_RS14005	COG2233	PERMEase
GZS08_RS14010	COG3729	General stress protein
GZS08_RS14045	COG3381	protein complex oligomerization
GZS08_RS14050	COG0243	molybdopterin cofactor binding
GZS08_RS14055	COG3005	denitrification pathway
GZS08_RS14060	COG0745	RESPONSE REGULATOR receiver
GZS08_RS14065	COG1879	ABC-type sugar transport system periplasmic component
GZS08_RS14070	COG0784	Response regulator, receiver
GZS08_RS14070	COG2198	Histidine kinase
GZS08_RS14070	COG2205	protein histidine kinase activity
GZS08_RS14075	COG0348	domain, Protein
GZS08_RS14095	COG1278	Cold shock
GZS08_RS14100	COG1278	Cold shock
GZS08_RS14120	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GZS08_RS14125	COG1596	polysaccharide export
GZS08_RS14130	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GZS08_RS14135	COG3206	protein involved in exopolysaccharide biosynthesis
GZS08_RS14135	COG0489	protein tyrosine kinase activity
GZS08_RS14150	COG1294	oxidase, subunit
GZS08_RS14155	COG1271	oxidase subunit
GZS08_RS14160	COG1773	rubredoxin
GZS08_RS14165	COG1999	signal sequence binding
GZS08_RS14170	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GZS08_RS14175	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
GZS08_RS14180	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
GZS08_RS14185	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
GZS08_RS14195	COG0670	Belongs to the BI1 family
GZS08_RS14200	COG2920	part of a sulfur-relay system
GZS08_RS14205	COG1254	Belongs to the acylphosphatase family
GZS08_RS14220	COG1832	CoA-binding protein
GZS08_RS14235	COG0210	DNA helicase
GZS08_RS14240	COG3304	Inner membrane component domain
GZS08_RS14245	COG1289	transmembrane transporter activity
GZS08_RS14250	COG3070	regulator of competence-specific genes
GZS08_RS14260	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GZS08_RS14260	COG2885	chlorophyll binding
GZS08_RS14270	COG1067	ATP-dependent peptidase activity
GZS08_RS14280	COG3130	regulation of translation
GZS08_RS14285	COG3009	Protein conserved in bacteria
GZS08_RS14290	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GZS08_RS14290	COG3008	intermembrane lipid transfer
GZS08_RS14295	COG2995	paraquat-inducible protein a
GZS08_RS14300	COG0488	(ABC) transporter
GZS08_RS14310	COG0633	Ferredoxin
GZS08_RS14310	COG3217	Mosc domain protein beta barrel domain protein
GZS08_RS14325	COG3121	Chaperone
GZS08_RS14330	COG3539	Fimbrial protein
GZS08_RS14335	COG3539	Fimbrial protein
GZS08_RS14340	COG3539	Fimbrial protein
GZS08_RS14345	COG3188	usher protein
GZS08_RS14350	COG3121	Chaperone
GZS08_RS14355	COG3539	Fimbrial protein
GZS08_RS14360	COG0431	NADPH-dependent FMN reductase
GZS08_RS14365	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GZS08_RS14375	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GZS08_RS14380	COG1116	anion transmembrane transporter activity
GZS08_RS14385	COG0308	aminopeptidase N
GZS08_RS14405	COG1448	Aminotransferase
GZS08_RS14410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GZS08_RS14415	COG3108	Peptidase M15
GZS08_RS14420	COG2989	Protein conserved in bacteria
GZS08_RS14430	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
GZS08_RS14440	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GZS08_RS14445	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GZS08_RS14450	COG3173	Aminoglycoside phosphotransferase
GZS08_RS14465	COG3214	Protein conserved in bacteria
GZS08_RS14470	COG1663	tetraacyldisaccharide 4'-kinase activity
GZS08_RS14475	COG1132	(ABC) transporter
GZS08_RS14480	COG0658	competence protein
GZS08_RS14480	COG2333	competence protein COMEC
GZS08_RS14490	COG0539	negative regulation of cytoplasmic translation
GZS08_RS14500	COG0501	Belongs to the peptidase M48B family
GZS08_RS14515	COG2323	membrane
GZS08_RS14520	COG1944	ATP diphosphatase activity
GZS08_RS14525	COG2116	formate transmembrane transporter activity
GZS08_RS14530	COG1882	Formate acetyltransferase
GZS08_RS14535	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GZS08_RS14540	COG2249	NAD(P)H dehydrogenase (quinone) activity
GZS08_RS14545	COG0583	DNA-binding transcription factor activity
GZS08_RS14550	COG0531	amino acid
GZS08_RS14560	COG1335	isochorismatase
GZS08_RS14565	COG3302	dmso reductase anchor subunit
GZS08_RS14570	COG0437	4 iron, 4 sulfur cluster binding
GZS08_RS14575	COG0243	molybdopterin cofactor binding
GZS08_RS14585	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GZS08_RS14595	COG1674	ftsk spoiiie
GZS08_RS14595	COG1178	ABC-type Fe3 transport system permease component
GZS08_RS14600	COG1522	sequence-specific DNA binding
GZS08_RS14605	COG0492	ferredoxin-NADP+ reductase activity
GZS08_RS14610	COG4988	ABC transporter
GZS08_RS14615	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GZS08_RS14635	COG0542	response to heat
GZS08_RS14645	COG1278	Cold shock
GZS08_RS14650	COG1136	(ABC) transporter
GZS08_RS14650	COG0577	efflux transmembrane transporter activity
GZS08_RS14655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GZS08_RS14660	COG2990	Protein conserved in bacteria
GZS08_RS14665	COG3593	DNA synthesis involved in DNA repair
GZS08_RS14675	COG2431	L-lysine efflux transmembrane transporter activity
GZS08_RS14685	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GZS08_RS14690	COG0028	Belongs to the TPP enzyme family
GZS08_RS14695	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
GZS08_RS14700	COG0702	epimerase
GZS08_RS14705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GZS08_RS14710	COG3023	N-Acetylmuramoyl-L-alanine amidase
GZS08_RS14725	COG1126	abc transporter atp-binding protein
GZS08_RS14730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GZS08_RS14735	COG4215	(ABC) transporter
GZS08_RS14740	COG4160	amino acid transport
GZS08_RS14745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GZS08_RS14760	COG1177	transmembrane transport
GZS08_RS14765	COG1176	ABC-type spermidine putrescine transport system, permease component I
GZS08_RS14770	COG3842	ATPase activity
GZS08_RS14775	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GZS08_RS14790	COG0778	Nitroreductase
GZS08_RS14800	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GZS08_RS14815	COG3226	Transcriptional regulator
GZS08_RS14820	COG0738	Major facilitator superfamily
GZS08_RS14825	COG0561	phosphatase activity
GZS08_RS14835	COG2814	Major facilitator Superfamily
GZS08_RS14840	COG0671	phosphoesterase, PA-phosphatase related
GZS08_RS14845	COG1349	DNA-binding transcription factor activity
GZS08_RS14850	COG1686	Belongs to the peptidase S11 family
GZS08_RS14855	COG0625	glutathione transferase activity
GZS08_RS14860	COG2133	pyrroloquinoline quinone binding
GZS08_RS14875	COG2199	diguanylate cyclase activity
GZS08_RS14885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GZS08_RS14895	COG0747	negative chemotaxis
GZS08_RS14900	COG4172	Belongs to the ABC transporter superfamily
GZS08_RS14905	COG1446	asparaginase
GZS08_RS14910	COG0303	'Molybdopterin
GZS08_RS14915	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GZS08_RS14920	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GZS08_RS14925	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GZS08_RS14930	COG1882	Formate acetyltransferase
GZS08_RS14935	COG0561	phosphatase activity
GZS08_RS14945	COG0488	(ABC) transporter
GZS08_RS14950	COG1376	ErfK ybiS ycfS ynhG family protein
GZS08_RS14955	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GZS08_RS14960	COG1321	iron dependent repressor
GZS08_RS14970	COG2194	sulfuric ester hydrolase activity
GZS08_RS14975	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GZS08_RS14985	COG5006	permease, DMT superfamily
GZS08_RS14995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GZS08_RS15000	COG0765	amino acid transport
GZS08_RS15005	COG1126	abc transporter atp-binding protein
GZS08_RS15010	COG0668	transmembrane transport
GZS08_RS15025	COG4774	siderophore transport
GZS08_RS15035	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GZS08_RS15045	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GZS08_RS15050	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GZS08_RS15055	COG1199	ATP-dependent helicase activity
GZS08_RS15060	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
GZS08_RS15065	COG0513	Belongs to the DEAD box helicase family
GZS08_RS15070	COG1309	transcriptional regulator
GZS08_RS15080	COG1131	(ABC) transporter
GZS08_RS15085	COG0842	Transport permease protein
GZS08_RS15090	COG0842	Transport permease protein
GZS08_RS15100	COG3568	Endonuclease Exonuclease Phosphatase
GZS08_RS15105	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GZS08_RS15110	COG0392	lysyltransferase activity
GZS08_RS15115	COG0670	Belongs to the BI1 family
GZS08_RS15120	COG0670	Belongs to the BI1 family
GZS08_RS15125	COG0314	molybdopterin synthase activity
GZS08_RS15130	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GZS08_RS15140	COG0521	Mo-molybdopterin cofactor biosynthetic process
GZS08_RS15150	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GZS08_RS15160	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GZS08_RS15165	COG2226	methyltransferase
GZS08_RS15180	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GZS08_RS15185	COG1881	PFAM PEBP family protein
GZS08_RS15190	COG4677	pectinesterase activity
GZS08_RS15195	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GZS08_RS15200	COG0471	metal ion transport
GZS08_RS15205	COG2828	Protein conserved in bacteria
GZS08_RS15210	COG0583	DNA-binding transcription factor activity
GZS08_RS15220	COG0561	phosphatase activity
GZS08_RS15225	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GZS08_RS15230	COG4149	molybdate abc transporter
GZS08_RS15235	COG0725	ABC transporter, periplasmic molybdate-binding protein
GZS08_RS15245	COG2005	Transcriptional regulator
GZS08_RS15245	COG3585	molybdate ion transport
GZS08_RS15250	COG1119	ATPase activity
GZS08_RS15255	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GZS08_RS15260	COG1085	galactose-1-phosphate uridylyltransferase
GZS08_RS15270	COG2017	converts alpha-aldose to the beta-anomer
GZS08_RS15280	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GZS08_RS15290	COG1230	cation diffusion facilitator family transporter
GZS08_RS15295	COG3201	nicotinamide mononucleotide transporter
GZS08_RS15345	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GZS08_RS15350	COG2885	chlorophyll binding
GZS08_RS15360	COG3064	Membrane
GZS08_RS15365	COG0848	biopolymer transport protein
GZS08_RS15370	COG0811	peptide transport
GZS08_RS15375	COG0824	Thioesterase
GZS08_RS15380	COG3790	cyd operon protein YbgE
GZS08_RS15385	COG4890	Cyd operon protein YbgT
GZS08_RS15390	COG1294	oxidase, subunit
GZS08_RS15395	COG1271	oxidase subunit
GZS08_RS15405	COG0383	alpha-mannosidase activity
GZS08_RS15410	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GZS08_RS15410	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GZS08_RS15410	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GZS08_RS15415	COG2188	Transcriptional regulator
GZS08_RS15420	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GZS08_RS15430	COG0508	dehydrogenase complex catalyzes the overall conversion of
GZS08_RS15435	COG0567	Dehydrogenase, E1 component
GZS08_RS15440	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GZS08_RS15445	COG1053	succinate dehydrogenase
GZS08_RS15450	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GZS08_RS15455	COG2009	succinate dehydrogenase
GZS08_RS15465	COG0372	Belongs to the citrate synthase family
GZS08_RS15470	COG3539	Fimbrial protein
GZS08_RS15475	COG3188	usher protein
GZS08_RS15480	COG3121	Chaperone
GZS08_RS15485	COG3539	Fimbrial protein
GZS08_RS15490	COG3180	Ammonia monooxygenase
GZS08_RS15505	COG1984	allophanate hydrolase subunit 2
GZS08_RS15510	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GZS08_RS15515	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GZS08_RS15520	COG3104	oligopeptide transport
GZS08_RS15525	COG0415	Belongs to the DNA photolyase family
GZS08_RS15530	COG3272	Protein of unknown function (DUF1722)
GZS08_RS15565	COG3209	COG3209 Rhs family protein
GZS08_RS15595	COG2205	protein histidine kinase activity
GZS08_RS15600	COG0745	RESPONSE REGULATOR receiver
GZS08_RS15615	COG0531	amino acid
GZS08_RS15635	COG0033	Phosphoglucomutase
GZS08_RS15640	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
GZS08_RS15645	COG0596	Alpha beta hydrolase
GZS08_RS15655	COG0716	FMN binding
GZS08_RS15665	COG0735	belongs to the Fur family
GZS08_RS15685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GZS08_RS15685	COG2190	(PTS) system
GZS08_RS15685	COG1263	PTS System
GZS08_RS15695	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GZS08_RS15700	COG1846	Transcriptional regulator
GZS08_RS15700	COG1940	carbohydrate kinase activity
GZS08_RS15705	COG0647	UMP catabolic process
GZS08_RS15710	COG0367	asparagine synthase
GZS08_RS15750	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GZS08_RS15760	COG1702	phosphate starvation-inducible protein PhoH
GZS08_RS15770	COG4535	Mg2 and Co2 transporter CorC
GZS08_RS15775	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GZS08_RS15780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GZS08_RS15785	COG0765	amino acid transport
GZS08_RS15790	COG0765	amino acid transport
GZS08_RS15795	COG1126	abc transporter atp-binding protein
GZS08_RS15805	COG0443	Heat shock 70 kDa protein
GZS08_RS15810	COG2214	Heat shock protein DnaJ domain protein
GZS08_RS15820	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GZS08_RS15825	COG2214	Heat shock protein DnaJ domain protein
GZS08_RS15835	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GZS08_RS15840	COG2888	peptidyl-tyrosine sulfation
GZS08_RS15855	COG1466	dna polymerase III delta subunit
GZS08_RS15865	COG0406	alpha-ribazole phosphatase activity
GZS08_RS15870	COG0799	negative regulation of ribosome biogenesis
GZS08_RS15880	COG0768	penicillin binding
GZS08_RS15885	COG0772	Belongs to the SEDS family
GZS08_RS15890	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GZS08_RS15895	COG1686	Belongs to the peptidase S11 family
GZS08_RS15910	COG0583	DNA-binding transcription factor activity
GZS08_RS15920	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GZS08_RS15945	COG3069	C4-dicarboxylate transmembrane transporter activity
GZS08_RS15950	COG4565	transcriptional regulatory protein
GZS08_RS15955	COG3290	protein histidine kinase activity
GZS08_RS15960	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
GZS08_RS15970	COG2301	Belongs to the HpcH HpaI aldolase family
GZS08_RS15975	COG3051	citrate lyase alpha subunit
GZS08_RS15990	COG0471	metal ion transport
GZS08_RS15995	COG3719	Belongs to the RNase T2 family
GZS08_RS16000	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GZS08_RS16005	COG1063	alcohol dehydrogenase
GZS08_RS16010	COG0589	response to stress
GZS08_RS16015	COG3634	alkyl hydroperoxide reductase activity
GZS08_RS16020	COG0450	alkyl hydroperoxide reductase
GZS08_RS16025	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GZS08_RS16030	COG0583	DNA-binding transcription factor activity
GZS08_RS16035	COG3969	phosphoadenosine phosphosulfate
GZS08_RS16040	COG1475	DNA binding
GZS08_RS16045	COG0436	Aminotransferase
GZS08_RS16050	COG0371	Dehydrogenase
GZS08_RS16055	COG2879	small protein
GZS08_RS16060	COG1966	Carbon starvation protein
GZS08_RS16065	COG2050	protein possibly involved in aromatic compounds catabolism
GZS08_RS16070	COG1028	Short-chain dehydrogenase reductase Sdr
GZS08_RS16075	COG3433	isochorismatase activity
GZS08_RS16075	COG1535	isochorismatase
GZS08_RS16080	COG1021	2,3-dihydroxybenzoate-AMP ligase
GZS08_RS16085	COG1169	isochorismate synthase
GZS08_RS16090	COG4592	Periplasmic binding protein
GZS08_RS16100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GZS08_RS16105	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GZS08_RS16110	COG1120	ATPase activity
GZS08_RS16115	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
GZS08_RS16120	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GZS08_RS16120	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GZS08_RS16125	COG3251	PFAM MbtH domain protein
GZS08_RS16130	COG2382	esterase
GZS08_RS16140	COG4771	TonB-dependent receptor
GZS08_RS16145	COG2977	Belongs to the P-Pant transferase superfamily
GZS08_RS16150	COG3385	transposase activity
GZS08_RS16185	COG3423	Transcriptional regulator
GZS08_RS16205	COG0500	methyltransferase
GZS08_RS16210	COG0438	transferase activity, transferring glycosyl groups
GZS08_RS16215	COG0438	transferase activity, transferring glycosyl groups
GZS08_RS16255	COG0778	Nitroreductase
GZS08_RS16260	COG0668	transmembrane transport
GZS08_RS16265	COG1113	amino acid transport
GZS08_RS16270	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GZS08_RS16275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GZS08_RS16280	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GZS08_RS16285	COG1538	Outer membrane efflux protein
GZS08_RS16290	COG0745	RESPONSE REGULATOR receiver
GZS08_RS16295	COG5002	protein histidine kinase activity
GZS08_RS16300	COG1215	transferase activity, transferring glycosyl groups
GZS08_RS16305	COG4783	chaperone-mediated protein folding
GZS08_RS16315	COG2207	Transcriptional regulator
GZS08_RS16325	COG2197	response regulator
GZS08_RS16330	COG3539	Fimbrial protein
GZS08_RS16335	COG3539	Fimbrial protein
GZS08_RS16340	COG3188	usher protein
GZS08_RS16345	COG3121	Chaperone
GZS08_RS16350	COG3539	Fimbrial protein
GZS08_RS16360	COG2501	S4 domain
GZS08_RS16365	COG1988	membrane-bound metal-dependent
GZS08_RS16375	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GZS08_RS16385	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GZS08_RS16390	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GZS08_RS16395	COG0549	Belongs to the carbamate kinase family
GZS08_RS16405	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GZS08_RS16410	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GZS08_RS16415	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GZS08_RS16420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GZS08_RS16425	COG3257	ureidoglycine aminohydrolase activity
GZS08_RS16430	COG1929	Belongs to the glycerate kinase type-1 family
GZS08_RS16435	COG2233	PERMEase
GZS08_RS16445	COG1953	Uracil, thiamine, allantoin
GZS08_RS16450	COG2084	Dehydrogenase
GZS08_RS16460	COG3960	tartronate-semialdehyde synthase activity
GZS08_RS16465	COG1414	Transcriptional regulator
GZS08_RS16475	COG0583	DNA-binding transcription factor activity
GZS08_RS16495	COG3209	COG3209 Rhs family protein
GZS08_RS16505	COG3209	COG3209 Rhs family protein
GZS08_RS16510	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GZS08_RS16515	COG4181	ATPase activity
GZS08_RS16520	COG2755	lipolytic protein G-D-S-L family
GZS08_RS16525	COG0300	oxidoreductase activity
GZS08_RS16530	COG3118	belongs to the thioredoxin family
GZS08_RS16535	COG0390	transport system, permease component
GZS08_RS16540	COG4619	ABC transporter
GZS08_RS16545	COG0330	HflC and HflK could
GZS08_RS16550	COG1585	Membrane protein implicated in regulation of membrane protease activity
GZS08_RS16555	COG0789	Transcriptional regulator
GZS08_RS16560	COG0531	amino acid
GZS08_RS16565	COG2066	Belongs to the glutaminase family
GZS08_RS16570	COG2217	Heavy metal translocating P-type atpase
GZS08_RS16575	COG3093	addiction module antidote protein HigA
GZS08_RS16580	COG3735	TraB family
GZS08_RS16585	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GZS08_RS16590	COG0737	Belongs to the 5'-nucleotidase family
GZS08_RS16595	COG2223	nitrite transmembrane transporter activity
GZS08_RS16600	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GZS08_RS16600	COG4651	solute:proton antiporter activity
GZS08_RS16605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GZS08_RS16640	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GZS08_RS16650	COG2832	Protein of unknown function (DUF454)
GZS08_RS16655	COG3923	Primosomal replication protein n
GZS08_RS16665	COG1196	nuclear chromosome segregation
GZS08_RS16665	COG3264	Mechanosensitive ion channel
GZS08_RS16675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GZS08_RS16680	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GZS08_RS16695	COG0110	maltose O-acetyltransferase activity
GZS08_RS16705	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GZS08_RS16710	COG5507	3-demethylubiquinone-9 3-methyltransferase
GZS08_RS16720	COG3695	enzyme binding
GZS08_RS16725	COG3126	Type III secretion system lipoprotein chaperone (YscW)
GZS08_RS16730	COG1946	Acyl-CoA thioesterase
GZS08_RS16735	COG0004	ammonium transporteR
GZS08_RS16740	COG0347	Belongs to the P(II) protein family
GZS08_RS16745	COG1132	(ABC) transporter
GZS08_RS16750	COG1132	(ABC) transporter
GZS08_RS16755	COG1522	sequence-specific DNA binding
GZS08_RS16765	COG4533	DNA binding
GZS08_RS16775	COG0824	Thioesterase
GZS08_RS16780	COG1555	photosystem II stabilization
GZS08_RS16785	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GZS08_RS16790	COG0776	regulation of translation
GZS08_RS16795	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GZS08_RS16815	COG0271	Belongs to the BolA IbaG family
GZS08_RS16820	COG3056	Lipoprotein
GZS08_RS16825	COG2223	nitrite transmembrane transporter activity
GZS08_RS16830	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GZS08_RS16835	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GZS08_RS16840	COG1845	cytochrome c oxidase, subunit III
GZS08_RS16845	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GZS08_RS16855	COG2814	Major facilitator Superfamily
GZS08_RS16865	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GZS08_RS16870	COG0693	protein deglycase activity
GZS08_RS16885	COG0142	geranyltranstransferase activity
GZS08_RS16895	COG0667	Aldo Keto reductase
GZS08_RS16900	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GZS08_RS16905	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GZS08_RS16920	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GZS08_RS16920	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GZS08_RS16930	COG4238	major outer membrane lipoprotein
GZS08_RS16935	COG3248	Nucleoside-binding outer membrane protein
GZS08_RS16940	COG1403	HNH endonuclease
GZS08_RS16945	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GZS08_RS16950	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GZS08_RS16955	COG1862	Preprotein translocase
GZS08_RS16975	COG0366	Alpha amylase catalytic
GZS08_RS16980	COG1113	amino acid transport
GZS08_RS16985	COG1114	Component of the transport system for branched-chain amino acids
GZS08_RS16990	COG5002	protein histidine kinase activity
GZS08_RS16995	COG0745	RESPONSE REGULATOR receiver
GZS08_RS17000	COG0420	3'-5' exonuclease activity
GZS08_RS17005	COG0419	ATPase involved in DNA repair
GZS08_RS17010	COG2814	Major facilitator Superfamily
GZS08_RS17015	COG1940	carbohydrate kinase activity
GZS08_RS17040	COG4126	flavin adenine dinucleotide binding
GZS08_RS17060	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GZS08_RS17065	COG3706	GGDEF domain
GZS08_RS17075	COG1785	Belongs to the alkaline phosphatase family
GZS08_RS17090	COG1181	Belongs to the D-alanine--D-alanine ligase family
GZS08_RS17110	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
GZS08_RS17115	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GZS08_RS17120	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GZS08_RS17125	COG3468	outer membrane autotransporter barrel domain protein
GZS08_RS17130	COG0113	porphobilinogen synthase activity
GZS08_RS17135	COG2175	clavaminate synthase activity
GZS08_RS17140	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GZS08_RS17150	COG4521	taurine ABC transporter
GZS08_RS17160	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GZS08_RS17165	COG1215	transferase activity, transferring glycosyl groups
GZS08_RS17180	COG3547	Transposase (IS116 IS110 IS902 family)
GZS08_RS17200	COG3122	Protein conserved in bacteria
GZS08_RS17205	COG2814	Major facilitator Superfamily
GZS08_RS17220	COG3971	2-oxopent-4-enoate hydratase activity
GZS08_RS17240	COG1414	Transcriptional regulator
GZS08_RS17245	COG1609	Transcriptional regulator
GZS08_RS17250	COG3250	beta-galactosidase activity
GZS08_RS17255	COG2223	nitrite transmembrane transporter activity
GZS08_RS17260	COG0110	maltose O-acetyltransferase activity
GZS08_RS17265	COG2807	transmembrane transport
GZS08_RS17275	COG0288	reversible hydration of carbon dioxide
GZS08_RS17280	COG0583	DNA-binding transcription factor activity
GZS08_RS17285	COG0402	S-adenosylhomocysteine deaminase activity
GZS08_RS17290	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GZS08_RS17295	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GZS08_RS17300	COG2079	MmgE PrpD family protein
GZS08_RS17305	COG0372	Belongs to the citrate synthase family
GZS08_RS17310	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GZS08_RS17315	COG3829	transcription factor binding
GZS08_RS17325	COG1280	lysine exporter protein (LysE YggA)
GZS08_RS17340	COG1064	alcohol dehydrogenase
GZS08_RS17345	COG0402	S-adenosylhomocysteine deaminase activity
GZS08_RS17350	COG0549	Belongs to the carbamate kinase family
GZS08_RS17360	COG1304	FMN binding
GZS08_RS17365	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GZS08_RS17375	COG0666	response to abiotic stimulus
GZS08_RS17385	COG0583	DNA-binding transcription factor activity
GZS08_RS17390	COG2771	luxR family
GZS08_RS17390	COG2200	EAL domain
GZS08_RS17400	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GZS08_RS17425	COG1556	Lactate utilization protein
GZS08_RS17430	COG1139	Iron-sulfur cluster binding protein
GZS08_RS17435	COG0247	lactate metabolic process
GZS08_RS17440	COG2207	Transcriptional regulator
GZS08_RS17445	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GZS08_RS17455	COG3059	membrane
GZS08_RS17465	COG3708	Transcriptional regulator
GZS08_RS17465	COG2207	Transcriptional regulator
GZS08_RS17470	COG1388	LysM domain
GZS08_RS17515	COG3188	usher protein
GZS08_RS17525	COG3121	Chaperone
GZS08_RS17530	COG0727	PFAM Uncharacterised protein family (UPF0153)
GZS08_RS17535	COG3477	response to acidic pH
GZS08_RS17540	COG2080	2 iron, 2 sulfur cluster binding
GZS08_RS17545	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GZS08_RS17550	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GZS08_RS17555	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GZS08_RS17585	COG2003	Belongs to the UPF0758 family
GZS08_RS17610	COG2020	methyltransferase activity
GZS08_RS17690	COG1401	restriction endodeoxyribonuclease activity
GZS08_RS17710	COG3344	reverse transcriptase
GZS08_RS17725	COG2826	transposase and inactivated derivatives, IS30 family
GZS08_RS17745	COG2189	Belongs to the N(4) N(6)-methyltransferase family
GZS08_RS17750	COG1404	Belongs to the peptidase S8 family
GZS08_RS17755	COG0464	growth
GZS08_RS17760	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GZS08_RS17790	COG0531	amino acid
GZS08_RS17795	COG1982	Orn Lys Arg decarboxylase major
GZS08_RS17800	COG0531	amino acid
GZS08_RS17830	COG0582	viral genome integration into host DNA
GZS08_RS17850	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GZS08_RS17870	COG2195	Cleaves the N-terminal amino acid of tripeptides
GZS08_RS17885	COG0454	-acetyltransferase
GZS08_RS17895	COG2161	toxin-antitoxin pair type II binding
GZS08_RS17915	COG1943	Transposase
GZS08_RS17920	COG0791	NLP P60 protein
GZS08_RS17925	COG3077	Addiction module antitoxin, RelB DinJ family
GZS08_RS17930	COG3041	Addiction module toxin RelE StbE family
GZS08_RS17935	COG3034	peptidoglycan biosynthetic process
GZS08_RS17940	COG0121	glutamine amidotransferase
GZS08_RS17950	COG1960	acyl-CoA dehydrogenase activity
GZS08_RS17960	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GZS08_RS17965	COG5433	transposase activity
GZS08_RS17975	COG3209	COG3209 Rhs family protein
GZS08_RS18065	COG3157	Type VI secretion system effector, Hcp
GZS08_RS18070	COG4104	PAAR repeat-containing protein
GZS08_RS18090	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GZS08_RS18100	COG2226	methyltransferase
GZS08_RS18110	COG1388	LysM domain
GZS08_RS18110	COG0741	lytic transglycosylase activity
GZS08_RS18125	COG0583	DNA-binding transcription factor activity
GZS08_RS18130	COG0656	L-ascorbic acid biosynthetic process
GZS08_RS18165	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GZS08_RS18170	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GZS08_RS18175	COG2011	ABC-type metal ion transport system permease component
GZS08_RS18180	COG1464	Belongs to the NlpA lipoprotein family
GZS08_RS18190	COG1720	tRNA m6t6A37 methyltransferase activity
GZS08_RS18200	COG0791	NLP P60 protein
GZS08_RS18205	COG3015	lipoprotein NlpE involved in copper resistance
GZS08_RS18210	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GZS08_RS18215	COG4681	YaeQ
GZS08_RS18225	COG4568	rho-dependent transcription termination
GZS08_RS18230	COG0037	tRNA processing
GZS08_RS18235	COG0346	lactoylglutathione lyase activity
GZS08_RS18240	COG1982	Orn Lys Arg decarboxylase major
GZS08_RS18250	COG0587	DNA-directed DNA polymerase activity
GZS08_RS18275	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GZS08_RS18280	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
GZS08_RS18290	COG0750	zinc metalloprotease
GZS08_RS18295	COG0575	Belongs to the CDS family
GZS08_RS18300	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GZS08_RS18305	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GZS08_RS18330	COG0024	Methionine aminopeptidase
GZS08_RS18345	COG1408	metallophosphoesterase
GZS08_RS18355	COG3835	regulator
GZS08_RS18360	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GZS08_RS18375	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GZS08_RS18380	COG2860	membrane
GZS08_RS18405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GZS08_RS18410	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GZS08_RS18415	COG1120	ATPase activity
GZS08_RS18420	COG4774	siderophore transport
GZS08_RS18425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GZS08_RS18430	COG1643	Atp-dependent helicase
GZS08_RS18435	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GZS08_RS18445	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GZS08_RS18455	COG0617	tRNA 3'-terminal CCA addition
GZS08_RS18460	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GZS08_RS18465	COG3539	Fimbrial protein
GZS08_RS18470	COG3121	Chaperone
GZS08_RS18475	COG3188	usher protein
GZS08_RS18480	COG3539	Fimbrial protein
GZS08_RS18485	COG3539	Fimbrial protein
GZS08_RS18490	COG3539	Fimbrial protein
GZS08_RS18495	COG3539	Fimbrial protein
GZS08_RS18510	COG5464	transposase or invertase
GZS08_RS18520	COG0726	polysaccharide deacetylase
GZS08_RS18525	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GZS08_RS18530	COG0842	Transport permease protein
GZS08_RS18535	COG1131	(ABC) transporter
GZS08_RS18540	COG0288	reversible hydration of carbon dioxide
GZS08_RS18545	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GZS08_RS18550	COG4993	Dehydrogenase
GZS08_RS18555	COG2132	Multicopper oxidase
GZS08_RS18580	COG1049	propionate catabolic process, 2-methylcitrate cycle
GZS08_RS18585	COG3064	Membrane
GZS08_RS18590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GZS08_RS18595	COG0508	dehydrogenase complex catalyzes the overall conversion of
GZS08_RS18600	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GZS08_RS18605	COG2186	Transcriptional regulator
GZS08_RS18610	COG1113	amino acid transport
GZS08_RS18615	COG3725	Membrane protein required for beta-lactamase induction
GZS08_RS18620	COG3023	N-Acetylmuramoyl-L-alanine amidase
GZS08_RS18625	COG0157	Belongs to the NadC ModD family
GZS08_RS18630	COG4969	Belongs to the N-Me-Phe pilin family
GZS08_RS18635	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GZS08_RS18640	COG1459	type II secretion system
GZS08_RS18650	COG0237	dephospho-CoA kinase activity
GZS08_RS18665	COG0494	nUDIX hydrolase
GZS08_RS18685	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GZS08_RS18690	COG0849	cell division
GZS08_RS18695	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GZS08_RS18700	COG1181	Belongs to the D-alanine--D-alanine ligase family
GZS08_RS18715	COG0772	Belongs to the SEDS family
GZS08_RS18730	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GZS08_RS18735	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GZS08_RS18740	COG0768	penicillin binding
GZS08_RS18745	COG3116	cell division
GZS08_RS18755	COG2001	Belongs to the MraZ family
GZS08_RS18760	COG1609	Transcriptional regulator
GZS08_RS18770	COG0440	acetolactate synthase activity
GZS08_RS18775	COG0028	Belongs to the TPP enzyme family
GZS08_RS18785	COG0583	DNA-binding transcription factor activity
GZS08_RS18800	COG0473	3-isopropylmalate dehydrogenase activity
GZS08_RS18815	COG2814	Major facilitator Superfamily
GZS08_RS18825	COG4533	DNA binding
GZS08_RS18830	COG4143	(ABC) transporter
GZS08_RS18835	COG1178	ABC-type Fe3 transport system permease component
GZS08_RS18840	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
GZS08_RS18845	COG0586	Pfam SNARE associated Golgi protein
GZS08_RS18850	COG4977	sequence-specific DNA binding
GZS08_RS18855	COG1069	ribulokinase activity
GZS08_RS18860	COG2160	L-arabinose isomerase activity
GZS08_RS18865	COG0235	Class ii aldolase
GZS08_RS18870	COG0417	DNA replication proofreading
GZS08_RS18880	COG0564	pseudouridine synthase activity
GZS08_RS18900	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GZS08_RS18905	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GZS08_RS18910	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GZS08_RS18935	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GZS08_RS18950	COG2271	Major facilitator Superfamily
GZS08_RS18955	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
GZS08_RS18960	COG0644	oxidoreductase
GZS08_RS19010	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GZS08_RS19015	COG0505	Belongs to the CarA family
GZS08_RS19035	COG1047	Peptidyl-prolyl cis-trans
GZS08_RS19050	COG0196	riboflavin kinase activity
GZS08_RS19080	COG0583	DNA-binding transcription factor activity
GZS08_RS19100	COG3385	transposase activity
GZS08_RS19120	COG4735	regulation of single-species biofilm formation
GZS08_RS19125	COG1584	GPR1 FUN34 yaaH family protein
GZS08_RS19130	COG0521	Mo-molybdopterin cofactor biosynthetic process
GZS08_RS19135	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GZS08_RS19140	COG1115	amino acid carrier protein
GZS08_RS19155	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GZS08_RS19165	COG0460	homoserine dehydrogenase
GZS08_RS19165	COG0527	aspartate kinase activity
GZS08_RS19175	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
GZS08_RS19185	COG0745	RESPONSE REGULATOR receiver
GZS08_RS19190	COG4452	Inner membrane protein CreD
GZS08_RS19195	COG2205	protein histidine kinase activity
GZS08_RS19200	COG0745	RESPONSE REGULATOR receiver
GZS08_RS19205	COG3045	CreA protein
GZS08_RS19210	COG3708	Transcriptional regulator
GZS08_RS19210	COG2207	Transcriptional regulator
GZS08_RS19230	COG0741	lytic transglycosylase activity
GZS08_RS19235	COG0488	(ABC) transporter
GZS08_RS19245	COG3172	ATPase kinase involved in NAD metabolism
GZS08_RS19245	COG1056	cytidyltransferase-related domain
GZS08_RS19250	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GZS08_RS19255	COG0560	Phosphoserine phosphatase
GZS08_RS19260	COG3726	membrane protein affecting hemolysin expression
GZS08_RS19295	COG1328	CTP reductase activity
GZS08_RS19300	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GZS08_RS19305	COG0084	hydrolase, TatD family'
GZS08_RS19310	COG4667	esterase of the alpha-beta hydrolase superfamily
GZS08_RS19320	COG2823	Periplasmic or secreted lipoprotein
GZS08_RS19330	COG1011	Hydrolase
GZS08_RS19335	COG0456	acetyltransferase
GZS08_RS19340	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
GZS08_RS19370	COG4114	ferric iron reductase
GZS08_RS19375	COG2197	response regulator
GZS08_RS19380	COG2197	response regulator
GZS08_RS19385	COG2966	Psort location CytoplasmicMembrane, score
GZS08_RS19400	COG1484	DNA-dependent DNA replication
GZS08_RS19415	COG1063	alcohol dehydrogenase
GZS08_RS19420	COG1802	Transcriptional regulator
GZS08_RS19425	COG2271	Major facilitator Superfamily
GZS08_RS19430	COG0840	transmembrane signaling receptor activity
GZS08_RS19435	COG1966	Carbon starvation protein
GZS08_RS19440	COG2879	small protein
GZS08_RS19445	COG0523	cobalamin synthesis protein
GZS08_RS19465	COG2814	Major facilitator Superfamily
GZS08_RS19470	COG2733	membrane
GZS08_RS19475	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
GZS08_RS19480	COG1924	4 iron, 4 sulfur cluster binding
GZS08_RS19495	COG0477	Major facilitator Superfamily
GZS08_RS19505	COG3366	ferrous iron transmembrane transporter activity
GZS08_RS19510	COG0700	Nucleoside recognition
GZS08_RS19515	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GZS08_RS19520	COG0583	DNA-binding transcription factor activity
GZS08_RS19540	COG2186	Transcriptional regulator
GZS08_RS19545	COG0246	Mannitol dehydrogenase
GZS08_RS19555	COG2610	gluconate transmembrane transporter activity
GZS08_RS19570	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GZS08_RS19605	COG3436	PFAM IS66 Orf2 family protein
GZS08_RS19610	COG4372	Transposase
GZS08_RS19645	COG1595	DNA-templated transcription, initiation
GZS08_RS19650	COG3712	iron ion homeostasis
GZS08_RS19655	COG4772	TonB-dependent receptor
GZS08_RS19660	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GZS08_RS19665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GZS08_RS19670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GZS08_RS19675	COG1120	ATPase activity
GZS08_RS19680	COG2085	NADP oxidoreductase coenzyme F420-dependent
GZS08_RS19690	COG3344	reverse transcriptase
GZS08_RS19705	COG1309	transcriptional regulator
GZS08_RS19720	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GZS08_RS19735	COG2990	Protein conserved in bacteria
GZS08_RS19740	COG0297	glycogen (starch) synthase activity
GZS08_RS19745	COG0726	polysaccharide deacetylase
GZS08_RS19755	COG3344	reverse transcriptase
GZS08_RS19835	COG0582	viral genome integration into host DNA
GZS08_RS19845	COG1064	alcohol dehydrogenase
GZS08_RS19850	COG0433	COG0433 Predicted ATPase
GZS08_RS19855	COG0795	lipopolysaccharide-transporting ATPase activity
GZS08_RS19860	COG0795	lipopolysaccharide-transporting ATPase activity
GZS08_RS19870	COG2927	DNA polymerase III (CHI subunit)
GZS08_RS19885	COG0456	acetyltransferase
GZS08_RS19890	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
GZS08_RS19905	COG2731	YhcH YjgK YiaL family protein
GZS08_RS19910	COG1309	transcriptional regulator
GZS08_RS19915	COG1028	Short-chain dehydrogenase reductase Sdr
GZS08_RS19920	COG0251	oxidation-reduction process
GZS08_RS19940	COG0251	oxidation-reduction process
GZS08_RS19945	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GZS08_RS19955	COG1609	Transcriptional regulator
GZS08_RS19960	COG1263	PTS System
GZS08_RS19960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GZS08_RS19965	COG0366	Alpha amylase catalytic
GZS08_RS19970	COG1328	CTP reductase activity
GZS08_RS19975	COG0602	queuosine metabolic process
GZS08_RS19980	COG3783	Cytochrome b(562)
GZS08_RS19985	COG0312	modulator of DNA gyrase
GZS08_RS19995	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GZS08_RS20005	COG1172	Belongs to the binding-protein-dependent transport system permease family
GZS08_RS20015	COG1129	ABC transporter
GZS08_RS20020	COG1879	ABC-type sugar transport system periplasmic component
GZS08_RS20025	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GZS08_RS20030	COG2337	Toxic component of a toxin-antitoxin (TA) module
GZS08_RS20035	COG2336	PFAM SpoVT AbrB
GZS08_RS20040	COG2105	PFAM AIG2 family protein
GZS08_RS20045	COG2911	Protein conserved in bacteria
GZS08_RS20050	COG0729	surface antigen
GZS08_RS20060	COG1253	flavin adenine dinucleotide binding
GZS08_RS20070	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GZS08_RS20080	COG1218	3'(2'),5'-bisphosphate nucleotidase
GZS08_RS20085	COG0737	Belongs to the 5'-nucleotidase family
GZS08_RS20090	COG1733	regulation of RNA biosynthetic process
GZS08_RS20095	COG0702	epimerase
GZS08_RS20100	COG0697	spore germination
GZS08_RS20110	COG1113	amino acid transport
GZS08_RS20115	COG0545	Peptidyl-prolyl cis-trans isomerase
GZS08_RS20120	COG3061	Opacity-associated protein A
GZS08_RS20130	COG0675	Transposase, IS605 OrfB family
GZS08_RS20150	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GZS08_RS20170	COG3477	response to acidic pH
GZS08_RS20175	COG0235	Class ii aldolase
GZS08_RS20190	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GZS08_RS20195	COG3414	Phosphotransferase system galactitol-specific IIB component
GZS08_RS20215	COG1073	alpha beta
GZS08_RS20220	COG3650	response to hydrogen peroxide
GZS08_RS20230	COG1960	acyl-CoA dehydrogenase activity
GZS08_RS20235	COG0754	glutathionylspermidine amidase activity
GZS08_RS20240	COG5463	Belongs to the UPF0441 family
GZS08_RS20245	COG3766	membrane
GZS08_RS20265	COG2721	sulfolactate sulfo-lyase activity
GZS08_RS20270	COG2271	Major facilitator Superfamily
GZS08_RS20275	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GZS08_RS20280	COG1414	Transcriptional regulator
GZS08_RS20285	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GZS08_RS20290	COG0557	exoribonuclease II activity
GZS08_RS20305	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
GZS08_RS20310	COG0330	HflC and HflK could
GZS08_RS20315	COG0330	HflC and HflK could
GZS08_RS20320	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GZS08_RS20340	COG0860	N-Acetylmuramoyl-L-alanine amidase
GZS08_RS20345	COG0802	atpase or kinase
GZS08_RS20350	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GZS08_RS20350	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GZS08_RS20355	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GZS08_RS20395	COG3264	Mechanosensitive ion channel
GZS08_RS20395	COG1511	domain protein
GZS08_RS20410	COG0531	amino acid
GZS08_RS20420	COG1053	succinate dehydrogenase
GZS08_RS20425	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GZS08_RS20440	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GZS08_RS20445	COG3040	lipid binding
GZS08_RS20450	COG2076	Multidrug Resistance protein
GZS08_RS20455	COG5510	response to toxic substance
GZS08_RS20460	COG5510	response to toxic substance
GZS08_RS20470	COG1509	lysine 2,3-aminomutase activity
GZS08_RS20495	COG0531	amino acid
GZS08_RS20500	COG3030	protein affecting phage T7 exclusion by the F plasmid
GZS08_RS20505	COG1027	Aspartate ammonia-lyase
GZS08_RS20510	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GZS08_RS20520	COG4232	protein-disulfide reductase activity
GZS08_RS20525	COG1309	transcriptional regulator
GZS08_RS20535	COG3710	Transcriptional regulator
GZS08_RS20540	COG0531	amino acid
GZS08_RS20545	COG1982	Orn Lys Arg decarboxylase major
GZS08_RS20550	COG3104	oligopeptide transport
GZS08_RS20555	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GZS08_RS20570	COG2388	GCN5-related N-acetyl-transferase
GZS08_RS20575	COG3592	Divergent 4Fe-4S mono-cluster
GZS08_RS20580	COG3290	protein histidine kinase activity
GZS08_RS20585	COG4565	transcriptional regulatory protein
GZS08_RS20590	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GZS08_RS20595	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GZS08_RS20595	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GZS08_RS20600	COG3647	Membrane
GZS08_RS20620	COG1486	melibiose metabolic process
GZS08_RS20625	COG2169	Transcriptional regulator
GZS08_RS20630	COG1982	Orn Lys Arg decarboxylase major
GZS08_RS20635	COG2207	Transcriptional regulator
GZS08_RS20640	COG0531	amino acid
GZS08_RS20645	COG2194	sulfuric ester hydrolase activity
GZS08_RS20650	COG0745	RESPONSE REGULATOR receiver
GZS08_RS20655	COG0642	Histidine kinase
GZS08_RS20665	COG0477	Major facilitator Superfamily
GZS08_RS20680	COG2824	Alkylphosphonate utilization operon protein PhnA
GZS08_RS20685	COG2764	glyoxalase bleomycin resistance protein dioxygenase
GZS08_RS20690	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GZS08_RS20695	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
GZS08_RS20705	COG2188	Transcriptional regulator
GZS08_RS20710	COG3624	Phosphonate C-P lyase system protein PhnG
GZS08_RS20715	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
GZS08_RS20720	COG3626	phosphonate metabolism
GZS08_RS20725	COG3627	carbon phosphorus lyase activity
GZS08_RS20730	COG4107	phosphonate C-P lyase system protein PhnK
GZS08_RS20735	COG4778	phosphonate C-P lyase system protein PhnL
GZS08_RS20740	COG3454	Phosphonate metabolism
GZS08_RS20745	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
GZS08_RS20750	COG0456	acetyltransferase
GZS08_RS20755	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GZS08_RS20765	COG0698	ribose 5-phosphate isomerase
GZS08_RS20770	COG1737	Transcriptional regulator
GZS08_RS20775	COG1879	ABC-type sugar transport system periplasmic component
GZS08_RS20780	COG1129	ABC transporter
GZS08_RS20785	COG1172	Belongs to the binding-protein-dependent transport system permease family
GZS08_RS20790	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GZS08_RS20795	COG1940	carbohydrate kinase activity
GZS08_RS20800	COG2015	COG2015, Alkyl sulfatase and related hydrolases
GZS08_RS20810	COG1566	PFAM secretion protein HlyD family protein
GZS08_RS20815	COG1289	transmembrane transporter activity
GZS08_RS20820	COG1538	Outer membrane efflux protein
GZS08_RS20830	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GZS08_RS20835	COG1301	dicarboxylic acid transport
GZS08_RS20840	COG4235	cytochrome complex assembly
GZS08_RS20845	COG3088	subunit of a heme lyase
GZS08_RS20850	COG1138	Cytochrome C-type biogenesis protein
GZS08_RS20855	COG3301	Polysulphide reductase, NrfD
GZS08_RS20860	COG0437	4 iron, 4 sulfur cluster binding
GZS08_RS20865	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
GZS08_RS20875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GZS08_RS20880	COG3162	membrane
GZS08_RS20890	COG1357	PFAM Pentapeptide repeats (8 copies)
GZS08_RS20895	COG0025	NhaP-type Na H and K H
GZS08_RS20900	COG2252	PERMEase
GZS08_RS20905	COG0789	Transcriptional regulator
GZS08_RS20910	COG2207	Transcriptional regulator
GZS08_RS20915	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GZS08_RS20955	COG0629	single-stranded DNA binding
GZS08_RS20960	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GZS08_RS20965	COG2315	Protein conserved in bacteria
GZS08_RS20970	COG0432	Pfam Uncharacterised protein family UPF0047
GZS08_RS20975	COG3700	Belongs to the class B bacterial acid phosphatase family
GZS08_RS20985	COG1448	Aminotransferase
GZS08_RS20990	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GZS08_RS20995	COG0305	Participates in initiation and elongation during chromosome replication
GZS08_RS21000	COG0604	alcohol dehydrogenase
GZS08_RS21010	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GZS08_RS21025	COG0735	belongs to the Fur family
GZS08_RS21030	COG3237	CsbD-like
GZS08_RS21035	COG0534	Mate efflux family protein
GZS08_RS21045	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GZS08_RS21080	COG3842	ATPase activity
GZS08_RS21085	COG2182	Extracellular solute-binding protein
GZS08_RS21090	COG1175	transmembrane transport
GZS08_RS21095	COG3833	ABC-type maltose transport systems, permease component
GZS08_RS21100	COG0477	Major facilitator Superfamily
GZS08_RS21100	COG2814	Major facilitator Superfamily
GZS08_RS21120	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GZS08_RS21145	COG0527	aspartate kinase activity
GZS08_RS21155	COG1187	pseudouridine synthase activity
GZS08_RS21165	COG1283	sodium-dependent phosphate transmembrane transporter activity
GZS08_RS21170	COG0646	methionine synthase
GZS08_RS21170	COG1410	methionine synthase
GZS08_RS21175	COG1414	Transcriptional regulator
GZS08_RS21190	COG2224	Isocitrate lyase
GZS08_RS21195	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GZS08_RS21205	COG0456	acetyltransferase
GZS08_RS21240	COG0151	Belongs to the GarS family
GZS08_RS21245	COG2204	response regulator
GZS08_RS21250	COG4191	Histidine kinase
GZS08_RS21255	COG3678	ATP-independent chaperone mediated protein folding
GZS08_RS21270	COG3068	Protein conserved in bacteria
GZS08_RS21305	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GZS08_RS21310	COG2104	thiamine diphosphate biosynthetic process
GZS08_RS21320	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GZS08_RS21360	COG0250	Participates in transcription elongation, termination and antitermination
GZS08_RS21365	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GZS08_RS21400	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GZS08_RS21400	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GZS08_RS21405	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GZS08_RS21450	COG1309	transcriptional regulator
GZS08_RS21460	COG0583	DNA-binding transcription factor activity
GZS08_RS21475	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GZS08_RS21490	COG2194	sulfuric ester hydrolase activity
GZS08_RS21495	COG2207	Transcriptional regulator
GZS08_RS21500	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GZS08_RS21505	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GZS08_RS21510	COG1882	Formate acetyltransferase
GZS08_RS21515	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GZS08_RS21520	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GZS08_RS21525	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GZS08_RS21525	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GZS08_RS21525	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GZS08_RS21530	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GZS08_RS21535	COG0371	Dehydrogenase
GZS08_RS21540	COG3738	Protein conserved in bacteria
GZS08_RS21545	COG0697	spore germination
GZS08_RS21555	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GZS08_RS21560	COG0460	homoserine dehydrogenase
GZS08_RS21560	COG0527	aspartate kinase activity
GZS08_RS21565	COG0626	cystathionine gamma-synthase activity
GZS08_RS21575	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
GZS08_RS21585	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GZS08_RS21590	COG1609	Transcriptional regulator
GZS08_RS21595	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GZS08_RS21610	COG1575	Belongs to the MenA family. Type 1 subfamily
GZS08_RS21625	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GZS08_RS21635	COG1494	fructose-1,6-bisphosphatase
GZS08_RS21640	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GZS08_RS21645	COG0589	response to stress
GZS08_RS21650	COG3691	Protein conserved in bacteria
GZS08_RS21655	COG3152	Membrane
GZS08_RS21675	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GZS08_RS21740	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GZS08_RS21745	COG4372	Transposase
GZS08_RS21750	COG3436	PFAM IS66 Orf2 family protein
GZS08_RS21765	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
GZS08_RS21820	COG1484	DNA-dependent DNA replication
GZS08_RS21825	COG4584	PFAM Integrase catalytic
GZS08_RS21870	COG4974	Belongs to the 'phage' integrase family
GZS08_RS21875	COG3678	ATP-independent chaperone mediated protein folding
GZS08_RS21880	COG0745	RESPONSE REGULATOR receiver
GZS08_RS21885	COG2205	protein histidine kinase activity
GZS08_RS21890	COG2258	MOSC domain
GZS08_RS21900	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GZS08_RS21940	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GZS08_RS21945	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GZS08_RS21945	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GZS08_RS21950	COG1363	Peptidase, m42
GZS08_RS21955	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GZS08_RS21955	COG3711	transcriptional antiterminator
GZS08_RS21975	COG0437	4 iron, 4 sulfur cluster binding
GZS08_RS21980	COG2864	formate dehydrogenase
GZS08_RS21990	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GZS08_RS21995	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GZS08_RS22000	COG0456	acetyltransferase
GZS08_RS22015	COG1011	Hydrolase
GZS08_RS22020	COG1349	DNA-binding transcription factor activity
GZS08_RS22025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GZS08_RS22030	COG2084	Dehydrogenase
GZS08_RS22035	COG3684	Belongs to the aldolase LacD family
GZS08_RS22040	COG2942	2-epimerase
GZS08_RS22045	COG2017	converts alpha-aldose to the beta-anomer
GZS08_RS22050	COG1501	Belongs to the glycosyl hydrolase 31 family
GZS08_RS22055	COG2211	Major facilitator Superfamily
GZS08_RS22060	COG2211	Major facilitator Superfamily
GZS08_RS22065	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GZS08_RS22070	COG2271	Major facilitator Superfamily
GZS08_RS22075	COG1082	Xylose isomerase domain protein TIM barrel
GZS08_RS22080	COG2188	Transcriptional regulator
GZS08_RS22085	COG1217	gtp-binding protein TYPA
GZS08_RS22090	COG0174	glutamine synthetase
GZS08_RS22095	COG3852	Histidine kinase
GZS08_RS22100	COG2204	response regulator
GZS08_RS22110	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GZS08_RS22125	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GZS08_RS22125	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GZS08_RS22135	COG0204	Acyl-transferase
GZS08_RS22140	COG5339	Protein conserved in bacteria
GZS08_RS22145	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GZS08_RS22150	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GZS08_RS22155	COG3084	Protein conserved in bacteria
GZS08_RS22160	COG0746	molybdenum cofactor guanylyltransferase activity
GZS08_RS22165	COG1763	Mo-molybdopterin cofactor biosynthetic process
GZS08_RS22195	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
GZS08_RS22200	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GZS08_RS22205	COG1739	Uncharacterized protein family UPF0029
GZS08_RS22220	COG0183	Belongs to the thiolase family
GZS08_RS22225	COG0543	2 iron, 2 sulfur cluster binding
GZS08_RS22230	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GZS08_RS22235	COG0250	Participates in transcription elongation, termination and antitermination
GZS08_RS22240	COG0084	hydrolase, TatD family'
GZS08_RS22245	COG0805	protein transport
GZS08_RS22250	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GZS08_RS22255	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GZS08_RS22265	COG3165	ubiquinone biosynthetic process from chorismate
GZS08_RS22275	COG1322	Protein conserved in bacteria
GZS08_RS22280	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
GZS08_RS22285	COG0412	Dienelactone hydrolase
GZS08_RS22295	COG0583	DNA-binding transcription factor activity
GZS08_RS22300	COG0697	spore germination
GZS08_RS22305	COG0561	phosphatase activity
GZS08_RS22310	COG2267	carboxylic ester hydrolase activity
GZS08_RS22315	COG1280	lysine exporter protein (LysE YggA)
GZS08_RS22320	COG1280	lysine exporter protein (LysE YggA)
GZS08_RS22325	COG0514	ATP-dependent DNA helicase (RecQ)
GZS08_RS22330	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
GZS08_RS22335	COG2050	protein possibly involved in aromatic compounds catabolism
GZS08_RS22340	COG2962	Rard protein
GZS08_RS22355	COG0598	Magnesium transport protein CorA
GZS08_RS22360	COG3698	Phosphodiester glycosidase
GZS08_RS22365	COG0210	DNA helicase
GZS08_RS22370	COG1011	Hydrolase
GZS08_RS22380	COG3159	Protein conserved in bacteria
GZS08_RS22390	COG5567	small periplasmic lipoprotein
GZS08_RS22400	COG3072	Adenylate cyclase
GZS08_RS22410	COG1587	Uroporphyrinogen-III synthase
GZS08_RS22415	COG2959	enzyme of heme biosynthesis
GZS08_RS22420	COG3071	HemY protein
GZS08_RS22425	COG3119	arylsulfatase activity
GZS08_RS22430	COG0641	radical SAM
GZS08_RS22455	COG1113	amino acid transport
GZS08_RS22475	COG2244	polysaccharide biosynthetic process
GZS08_RS22480	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GZS08_RS22485	COG0456	acetyltransferase
GZS08_RS22490	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GZS08_RS22495	COG1088	dTDP-glucose 4,6-dehydratase activity
GZS08_RS22500	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GZS08_RS22505	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GZS08_RS22510	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
GZS08_RS22515	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GZS08_RS22520	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GZS08_RS22530	COG3118	belongs to the thioredoxin family
GZS08_RS22545	COG0210	DNA helicase
GZS08_RS22555	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GZS08_RS22565	COG0583	DNA-binding transcription factor activity
GZS08_RS22570	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GZS08_RS22580	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GZS08_RS22585	COG3978	acetolactate synthase activity
GZS08_RS22605	COG0606	chelatase, subunit chli
GZS08_RS22610	COG3085	chromosome segregation
GZS08_RS22650	COG2186	Transcriptional regulator
GZS08_RS22655	COG0477	Major facilitator Superfamily
GZS08_RS22660	COG1609	Transcriptional regulator
GZS08_RS22665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GZS08_RS22670	COG1879	ABC-type sugar transport system periplasmic component
GZS08_RS22675	COG1172	Belongs to the binding-protein-dependent transport system permease family
GZS08_RS22680	COG1129	ABC transporter
GZS08_RS22710	COG1522	sequence-specific DNA binding
GZS08_RS22715	COG0716	FMN binding
GZS08_RS22730	COG3312	ion transport
GZS08_RS22780	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GZS08_RS22785	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GZS08_RS22790	COG0573	inorganic phosphate transmembrane transporter activity
GZS08_RS22795	COG0581	inorganic phosphate transmembrane transporter activity
GZS08_RS22800	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GZS08_RS22805	COG0704	Plays a role in the regulation of phosphate uptake
GZS08_RS22810	COG3711	transcriptional antiterminator
GZS08_RS22815	COG1263	PTS System
GZS08_RS22815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GZS08_RS22815	COG2190	(PTS) system
GZS08_RS22820	COG2723	6-phospho-beta-galactosidase activity
GZS08_RS22830	COG2382	esterase
GZS08_RS22835	COG0363	glucosamine-6-phosphate deaminase activity
GZS08_RS22850	COG3436	PFAM IS66 Orf2 family protein
GZS08_RS22855	COG4372	Transposase
GZS08_RS22870	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GZS08_RS22875	COG2252	PERMEase
GZS08_RS22880	COG0431	NADPH-dependent FMN reductase
GZS08_RS22885	COG2091	lysine biosynthetic process via aminoadipic acid
GZS08_RS22900	COG0814	amino acid
GZS08_RS22960	COG1196	nuclear chromosome segregation
GZS08_RS23310	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
GZS08_RS23320	COG4584	PFAM Integrase catalytic
GZS08_RS23325	COG1484	DNA-dependent DNA replication
GZS08_RS23420	COG3173	Aminoglycoside phosphotransferase
GZS08_RS23495	COG1192	Involved in chromosome partitioning
GZS08_RS23630	COG4584	PFAM Integrase catalytic
GZS08_RS23635	COG1484	DNA-dependent DNA replication
GZS08_RS23755	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GZS08_RS23770	COG0741	lytic transglycosylase activity
GZS08_RS23910	COG0673	inositol 2-dehydrogenase activity
GZS08_RS24000	COG1253	flavin adenine dinucleotide binding
GZS08_RS24040	COG1749	Flagellar hook protein flgE
GZS08_RS24045	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GZS08_RS24110	COG0459	protein refolding