locus-tag	class	description
IB009_RS00010	COG0592	DNA-directed DNA polymerase activity
IB009_RS00020	COG0187	DNA topoisomerase II activity
IB009_RS00025	COG3753	Protein conserved in bacteria
IB009_RS00030	COG0561	phosphatase activity
IB009_RS00040	COG2186	Transcriptional regulator
IB009_RS00045	COG3734	2-keto-3-deoxy-galactonokinase
IB009_RS00050	COG0800	Aldolase
IB009_RS00060	COG2271	Major facilitator Superfamily
IB009_RS00070	COG0823	Involved in the tonB-independent uptake of proteins
IB009_RS00075	COG5645	(Lipo)protein
IB009_RS00095	COG2188	Transcriptional regulator
IB009_RS00110	COG2207	Transcriptional regulator
IB009_RS00115	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IB009_RS00120	COG3119	arylsulfatase activity
IB009_RS00130	COG2149	membrane
IB009_RS00140	COG0641	radical SAM
IB009_RS00145	COG2814	Major facilitator Superfamily
IB009_RS00160	COG0028	Belongs to the TPP enzyme family
IB009_RS00165	COG0440	acetolactate synthase activity
IB009_RS00170	COG2197	response regulator
IB009_RS00175	COG3851	Histidine kinase
IB009_RS00180	COG2271	Major facilitator Superfamily
IB009_RS00185	COG2271	Major facilitator Superfamily
IB009_RS00195	COG2252	PERMEase
IB009_RS00215	COG1464	Belongs to the NlpA lipoprotein family
IB009_RS00220	COG0697	spore germination
IB009_RS00235	COG2211	Major facilitator Superfamily
IB009_RS00240	COG1501	Belongs to the glycosyl hydrolase 31 family
IB009_RS00245	COG2982	Protein involved in outer membrane biogenesis
IB009_RS00250	COG2233	PERMEase
IB009_RS00255	COG0786	glutamate:sodium symporter activity
IB009_RS00265	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IB009_RS00270	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IB009_RS00275	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IB009_RS00285	COG0194	GDP metabolic process
IB009_RS00295	COG2860	membrane
IB009_RS00300	COG3645	SOS response
IB009_RS00310	COG1561	YicC-like family, N-terminal region
IB009_RS00335	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IB009_RS00365	COG1519	Transferase
IB009_RS00370	COG0859	PFAM glycosyl transferase family 9
IB009_RS00375	COG0438	transferase activity, transferring glycosyl groups
IB009_RS00380	COG0515	serine threonine protein kinase
IB009_RS00390	COG3642	lipopolysaccharide core region biosynthetic process
IB009_RS00410	COG0859	PFAM glycosyl transferase family 9
IB009_RS00415	COG0859	PFAM glycosyl transferase family 9
IB009_RS00430	COG0156	8-amino-7-oxononanoate synthase activity
IB009_RS00440	COG1216	Glycosyl transferase, family 2
IB009_RS00445	COG2861	carbohydrate metabolic process
IB009_RS00450	COG4942	peptidase
IB009_RS00460	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IB009_RS00465	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IB009_RS00480	COG1045	serine acetyltransferase
IB009_RS00485	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IB009_RS00495	COG2186	Transcriptional regulator
IB009_RS00500	COG1620	l-lactate permease
IB009_RS00505	COG5295	Hep Hag repeat protein
IB009_RS00525	COG3722	fumarate hydratase activity
IB009_RS00535	COG2213	PTS system mannitol-specific
IB009_RS00535	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IB009_RS00545	COG1566	PFAM secretion protein HlyD family protein
IB009_RS00555	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
IB009_RS00565	COG1413	lyase activity
IB009_RS00575	COG3209	COG3209 Rhs family protein
IB009_RS00580	COG0625	glutathione transferase activity
IB009_RS00590	COG3276	selenocysteine insertion sequence binding
IB009_RS00595	COG1454	alcohol dehydrogenase
IB009_RS00600	COG1012	belongs to the aldehyde dehydrogenase family
IB009_RS00615	COG1566	PFAM secretion protein HlyD family protein
IB009_RS00620	COG0583	DNA-binding transcription factor activity
IB009_RS00625	COG3713	MltA-interacting MipA family protein
IB009_RS00635	COG0235	Class ii aldolase
IB009_RS00640	COG3623	hexulose-6-phosphate isomerase
IB009_RS00645	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
IB009_RS00650	COG1070	Carbohydrate kinase
IB009_RS00655	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IB009_RS00660	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IB009_RS00665	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IB009_RS00690	COG1414	Transcriptional regulator
IB009_RS00695	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IB009_RS00700	COG3977	Valine--pyruvate aminotransferase
IB009_RS00705	COG0366	Alpha amylase catalytic
IB009_RS00710	COG2992	FlgJ-related protein
IB009_RS00715	COG2207	Transcriptional regulator
IB009_RS00715	COG1609	Transcriptional regulator
IB009_RS00720	COG4214	carbohydrate transport
IB009_RS00725	COG1129	ABC transporter
IB009_RS00730	COG4213	ABC transporter substrate-binding protein
IB009_RS00740	COG1070	Carbohydrate kinase
IB009_RS00745	COG4682	membrane
IB009_RS00750	COG4682	membrane
IB009_RS00755	COG3274	enterobacterial common antigen metabolic process
IB009_RS00780	COG1278	Cold shock
IB009_RS00785	COG2944	sequence-specific DNA binding
IB009_RS00800	COG2885	chlorophyll binding
IB009_RS00805	COG0243	molybdopterin cofactor binding
IB009_RS00810	COG0456	acetyltransferase
IB009_RS00815	COG2818	Glycosylase
IB009_RS00820	COG5571	outer membrane autotransporter
IB009_RS00825	COG2223	nitrite transmembrane transporter activity
IB009_RS00830	COG2194	sulfuric ester hydrolase activity
IB009_RS00845	COG0747	negative chemotaxis
IB009_RS00850	COG0601	transmembrane transport
IB009_RS00855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IB009_RS00860	COG0444	Belongs to the ABC transporter superfamily
IB009_RS00865	COG4608	Belongs to the ABC transporter superfamily
IB009_RS00870	COG0814	amino acid
IB009_RS00890	COG2194	sulfuric ester hydrolase activity
IB009_RS00920	COG1215	transferase activity, transferring glycosyl groups
IB009_RS00925	COG1215	transferase activity, transferring glycosyl groups
IB009_RS00930	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
IB009_RS00935	COG0457	Tetratricopeptide repeat
IB009_RS00935	COG3118	belongs to the thioredoxin family
IB009_RS00940	COG2200	EAL domain
IB009_RS00940	COG2199	diguanylate cyclase activity
IB009_RS00950	COG0612	Peptidase, M16
IB009_RS00960	COG2200	EAL domain
IB009_RS00965	COG2982	Protein involved in outer membrane biogenesis
IB009_RS00970	COG0477	Major facilitator Superfamily
IB009_RS00975	COG1295	ribonuclease BN
IB009_RS00980	COG0583	DNA-binding transcription factor activity
IB009_RS00985	COG2197	response regulator
IB009_RS00995	COG1858	cytochrome C peroxidase
IB009_RS01010	COG2207	Transcriptional regulator
IB009_RS01015	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IB009_RS01020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IB009_RS01030	COG2771	luxR family
IB009_RS01035	COG3247	response to pH
IB009_RS01050	COG1285	pathogenesis
IB009_RS01055	COG2197	response regulator
IB009_RS01060	COG3065	identical protein binding
IB009_RS01080	COG1393	Belongs to the ArsC family
IB009_RS01085	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IB009_RS01090	COG0640	Transcriptional regulator
IB009_RS01100	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IB009_RS01105	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IB009_RS01110	COG0339	signal peptide processing
IB009_RS01120	COG3104	oligopeptide transport
IB009_RS01125	COG0589	response to stress
IB009_RS01135	COG0306	phosphate transporter
IB009_RS01140	COG2081	HI0933 family
IB009_RS01205	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IB009_RS01235	COG0739	heme binding
IB009_RS01245	COG2132	Multicopper oxidase
IB009_RS01250	COG3667	copper resistance
IB009_RS01255	COG2372	response to copper ion
IB009_RS01260	COG1276	copper resistance
IB009_RS01265	COG0745	RESPONSE REGULATOR receiver
IB009_RS01270	COG2205	protein histidine kinase activity
IB009_RS01295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IB009_RS01300	COG0842	Transport permease protein
IB009_RS01300	COG1129	ABC transporter
IB009_RS01305	COG0842	Transport permease protein
IB009_RS01330	COG0444	Belongs to the ABC transporter superfamily
IB009_RS01335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IB009_RS01340	COG0601	transmembrane transport
IB009_RS01345	COG0747	negative chemotaxis
IB009_RS01350	COG2091	lysine biosynthetic process via aminoadipic acid
IB009_RS01355	COG0628	permease
IB009_RS01370	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IB009_RS01385	COG3714	YhhN family
IB009_RS01395	COG3776	membrane
IB009_RS01400	COG0742	ribosomal rna small subunit methyltransferase
IB009_RS01405	COG0552	protein localization to endoplasmic reticulum
IB009_RS01410	COG2884	Cell division ATP-binding protein ftsE
IB009_RS01415	COG2177	Part of the ABC transporter FtsEX involved in
IB009_RS01420	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IB009_RS01425	COG0683	leucine binding
IB009_RS01430	COG0456	acetyltransferase
IB009_RS01435	COG0683	leucine binding
IB009_RS01440	COG0559	Belongs to the binding-protein-dependent transport system permease family
IB009_RS01445	COG4177	L-phenylalanine transmembrane transporter activity
IB009_RS01450	COG0411	ABC transporter
IB009_RS01455	COG0410	ABC transporter
IB009_RS01460	COG1653	transport
IB009_RS01465	COG1175	transmembrane transport
IB009_RS01470	COG0395	ABC-type sugar transport system, permease component
IB009_RS01480	COG0584	glycerophosphoryl diester phosphodiesterase
IB009_RS01490	COG0405	Gamma-glutamyltransferase
IB009_RS01510	COG3157	Type VI secretion system effector, Hcp
IB009_RS01515	COG1247	-acetyltransferase
IB009_RS01520	COG0673	inositol 2-dehydrogenase activity
IB009_RS01525	COG1741	Belongs to the pirin family
IB009_RS01530	COG1609	Transcriptional regulator
IB009_RS01535	COG3265	gluconokinase activity
IB009_RS01540	COG2610	gluconate transmembrane transporter activity
IB009_RS01545	COG2095	MarC family integral membrane protein
IB009_RS01550	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IB009_RS01575	COG0058	SHG alpha-glucan phosphorylase activity
IB009_RS01580	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IB009_RS01600	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IB009_RS01615	COG1349	DNA-binding transcription factor activity
IB009_RS01620	COG4650	regulator
IB009_RS01625	COG1690	Belongs to the RtcB family
IB009_RS01640	COG0058	SHG alpha-glucan phosphorylase activity
IB009_RS01645	COG1640	4-alpha-glucanotransferase
IB009_RS01650	COG2610	gluconate transmembrane transporter activity
IB009_RS01670	COG5464	transposase or invertase
IB009_RS01680	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
IB009_RS01685	COG1918	ferrous iron import across plasma membrane
IB009_RS01690	COG2183	response to ionizing radiation
IB009_RS01695	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IB009_RS01715	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
IB009_RS01725	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IB009_RS01730	COG1011	Hydrolase
IB009_RS01740	COG0494	nUDIX hydrolase
IB009_RS01745	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IB009_RS01750	COG4972	Pilus assembly protein
IB009_RS01755	COG3166	PFAM Fimbrial assembly family protein
IB009_RS01770	COG4796	Type ii and iii secretion system protein
IB009_RS01785	COG3266	domain, Protein
IB009_RS01790	COG0338	D12 class N6 adenine-specific DNA methyltransferase
IB009_RS01795	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IB009_RS01805	COG0180	Tryptophanyl-tRNA synthetase
IB009_RS01810	COG2188	Transcriptional regulator
IB009_RS01820	COG3457	Alanine racemase
IB009_RS01825	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
IB009_RS01830	COG1735	metal-dependent hydrolase with the TIM-barrel fold
IB009_RS01845	COG0626	cystathionine gamma-synthase activity
IB009_RS01850	COG2188	Transcriptional regulator
IB009_RS01855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IB009_RS01860	COG1082	Xylose isomerase domain protein TIM barrel
IB009_RS01865	COG2222	sugar isomerase
IB009_RS01870	COG0531	amino acid
IB009_RS01885	COG2116	formate transmembrane transporter activity
IB009_RS01890	COG2146	nitrite reductase [NAD(P)H] activity
IB009_RS01895	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IB009_RS01905	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IB009_RS01915	COG2184	nucleotidyltransferase activity
IB009_RS01920	COG0512	Glutamine amidotransferase of anthranilate synthase
IB009_RS01925	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IB009_RS01930	COG1289	transmembrane transporter activity
IB009_RS01935	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IB009_RS01940	COG1765	OsmC-like protein
IB009_RS01945	COG3954	Phosphoribulokinase
IB009_RS01955	COG0429	hydrolase of the alpha beta-hydrolase fold
IB009_RS01960	COG0488	(ABC) transporter
IB009_RS01975	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
IB009_RS01980	COG1047	Peptidyl-prolyl cis-trans
IB009_RS01990	COG0545	Peptidyl-prolyl cis-trans isomerase
IB009_RS01995	COG2964	Protein conserved in bacteria
IB009_RS02065	COG0089	rRNA binding
IB009_RS02155	COG0201	protein transport
IB009_RS02195	COG0789	Transcriptional regulator
IB009_RS02200	COG3036	rescue of stalled ribosome
IB009_RS02210	COG0569	domain protein
IB009_RS02230	COG0758	DNA mediated transformation
IB009_RS02240	COG0551	DNA topoisomerase type I activity
IB009_RS02260	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IB009_RS02300	COG1126	abc transporter atp-binding protein
IB009_RS02305	COG0765	amino acid transport
IB009_RS02310	COG4597	amino acid ABC transporter
IB009_RS02315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IB009_RS02325	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IB009_RS02330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IB009_RS02335	COG1309	transcriptional regulator
IB009_RS02345	COG2189	Belongs to the N(4) N(6)-methyltransferase family
IB009_RS02355	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IB009_RS02365	COG4145	pantothenate transmembrane transporter activity
IB009_RS02370	COG3924	membrane
IB009_RS02375	COG0439	Biotin carboxylase
IB009_RS02380	COG0511	ligase activity, forming carbon-carbon bonds
IB009_RS02385	COG0604	alcohol dehydrogenase
IB009_RS02390	COG2200	EAL domain
IB009_RS02390	COG2199	diguanylate cyclase activity
IB009_RS02395	COG1077	Cell shape determining protein MreB Mrl
IB009_RS02400	COG1792	Involved in formation and maintenance of cell shape
IB009_RS02405	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IB009_RS02415	COG1530	ribonuclease E activity
IB009_RS02420	COG3164	Protein of unknown function
IB009_RS02425	COG0312	modulator of DNA gyrase
IB009_RS02430	COG0583	DNA-binding transcription factor activity
IB009_RS02450	COG2732	(Barnase) inhibitor
IB009_RS02470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IB009_RS02475	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IB009_RS02480	COG3105	Protein conserved in bacteria
IB009_RS02485	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IB009_RS02500	COG0625	glutathione transferase activity
IB009_RS02505	COG2969	positive regulation of protein catabolic process
IB009_RS02510	COG3069	C4-dicarboxylate transmembrane transporter activity
IB009_RS02540	COG2731	YhcH YjgK YiaL family protein
IB009_RS02545	COG4804	nuclease activity
IB009_RS02550	COG0493	'glutamate synthase
IB009_RS02555	COG0070	glutamate synthase
IB009_RS02555	COG0069	glutamate synthase activity
IB009_RS02555	COG0067	glutamate synthase
IB009_RS02560	COG1242	4 iron, 4 sulfur cluster binding
IB009_RS02565	COG2198	Histidine kinase
IB009_RS02565	COG5002	protein histidine kinase activity
IB009_RS02565	COG0784	Response regulator, receiver
IB009_RS02570	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
IB009_RS02580	COG0515	serine threonine protein kinase
IB009_RS02585	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IB009_RS02600	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IB009_RS02605	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
IB009_RS02610	COG1137	ATPase activity
IB009_RS02615	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IB009_RS02620	COG3117	lipopolysaccharide transmembrane transporter activity
IB009_RS02625	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IB009_RS02630	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IB009_RS02630	COG0517	IMP dehydrogenase activity
IB009_RS02635	COG0530	calcium, potassium:sodium antiporter activity
IB009_RS02640	COG1127	ABC transporter
IB009_RS02645	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IB009_RS02650	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IB009_RS02655	COG2854	intermembrane phospholipid transfer
IB009_RS02660	COG3113	response to antibiotic
IB009_RS02665	COG5007	Belongs to the BolA IbaG family
IB009_RS02675	COG3423	Transcriptional regulator
IB009_RS02680	COG0142	geranyltranstransferase activity
IB009_RS02695	COG0697	spore germination
IB009_RS02705	COG2027	D-alanyl-D-alanine carboxypeptidase
IB009_RS02710	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IB009_RS02715	COG1534	Rna-binding protein
IB009_RS02725	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IB009_RS02730	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IB009_RS02740	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IB009_RS02750	COG2194	sulfuric ester hydrolase activity
IB009_RS02770	COG0195	Participates in both transcription termination and antitermination
IB009_RS02810	COG0513	Belongs to the DEAD box helicase family
IB009_RS02815	COG0814	amino acid
IB009_RS02820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IB009_RS02825	COG0826	peptidase U32
IB009_RS02830	COG0826	peptidase U32
IB009_RS02835	COG3154	lipid carrier protein
IB009_RS02840	COG3153	acetyltransferase
IB009_RS02855	COG0693	protein deglycase activity
IB009_RS02860	COG0702	epimerase
IB009_RS02865	COG0701	Predicted permease
IB009_RS02870	COG2823	Periplasmic or secreted lipoprotein
IB009_RS02890	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IB009_RS02895	COG3539	Fimbrial protein
IB009_RS02900	COG3188	usher protein
IB009_RS02905	COG3121	Chaperone
IB009_RS02910	COG3539	Fimbrial protein
IB009_RS02915	COG0363	glucosamine-6-phosphate deaminase activity
IB009_RS02920	COG3716	PTS system mannose fructose sorbose family IID component
IB009_RS02925	COG3715	PTS system
IB009_RS02930	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IB009_RS02940	COG2222	sugar isomerase
IB009_RS02945	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IB009_RS02950	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
IB009_RS02955	COG3716	PTS system mannose fructose sorbose family IID component
IB009_RS02965	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IB009_RS02975	COG1349	DNA-binding transcription factor activity
IB009_RS02985	COG2002	toxin-antitoxin pair type II binding
IB009_RS02990	COG2721	sulfolactate sulfo-lyase activity
IB009_RS02995	COG2271	Major facilitator Superfamily
IB009_RS03005	COG2084	Dehydrogenase
IB009_RS03010	COG1929	Belongs to the glycerate kinase type-1 family
IB009_RS03035	COG0583	DNA-binding transcription factor activity
IB009_RS03040	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IB009_RS03050	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IB009_RS03055	COG1882	Formate acetyltransferase
IB009_RS03060	COG0251	oxidation-reduction process
IB009_RS03065	COG1760	l-serine dehydratase
IB009_RS03070	COG0814	amino acid
IB009_RS03085	COG1741	Belongs to the pirin family
IB009_RS03090	COG0583	DNA-binding transcription factor activity
IB009_RS03095	COG3152	Membrane
IB009_RS03100	COG3152	Membrane
IB009_RS03105	COG0435	Glutathione S-transferase
IB009_RS03110	COG2259	Doxx family
IB009_RS03120	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
IB009_RS03125	COG4575	ribosome binding
IB009_RS03130	COG1422	Protein of unknown function (DUF1090)
IB009_RS03140	COG0586	Pfam SNARE associated Golgi protein
IB009_RS03145	COG2186	Transcriptional regulator
IB009_RS03170	COG2271	Major facilitator Superfamily
IB009_RS03180	COG2721	sulfolactate sulfo-lyase activity
IB009_RS03190	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
IB009_RS03195	COG0861	Integral membrane protein TerC family
IB009_RS03200	COG0673	inositol 2-dehydrogenase activity
IB009_RS03205	COG2949	membrane
IB009_RS03210	COG1451	nucleotide metabolic process
IB009_RS03220	COG4680	protein conserved in bacteria
IB009_RS03225	COG5499	transcription regulator containing HTH domain
IB009_RS03230	COG0446	pyridine nucleotide-disulphide oxidoreductase
IB009_RS03230	COG1902	pentaerythritol trinitrate reductase activity
IB009_RS03235	COG3408	Glycogen debranching enzyme
IB009_RS03235	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
IB009_RS03245	COG0531	amino acid
IB009_RS03250	COG2731	YhcH YjgK YiaL family protein
IB009_RS03255	COG3250	beta-galactosidase activity
IB009_RS03260	COG1609	Transcriptional regulator
IB009_RS03265	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IB009_RS03275	COG0840	transmembrane signaling receptor activity
IB009_RS03280	COG1695	Transcriptional regulator
IB009_RS03285	COG2375	cellular response to nickel ion
IB009_RS03370	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IB009_RS03375	COG0358	DNA primase activity
IB009_RS03380	COG0828	Belongs to the bacterial ribosomal protein bS21 family
IB009_RS03390	COG0471	metal ion transport
IB009_RS03395	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IB009_RS03400	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IB009_RS03405	COG0583	DNA-binding transcription factor activity
IB009_RS03415	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IB009_RS03430	COG4991	sh3 domain protein
IB009_RS03435	COG3025	triphosphatase activity
IB009_RS03460	COG2268	Band 7 protein
IB009_RS03465	COG1585	Membrane protein implicated in regulation of membrane protease activity
IB009_RS03475	COG3539	Fimbrial protein
IB009_RS03480	COG3121	Chaperone
IB009_RS03485	COG3188	usher protein
IB009_RS03490	COG3539	Fimbrial protein
IB009_RS03500	COG2960	long-chain fatty acid transporting porin activity
IB009_RS03520	COG3384	dioxygenase
IB009_RS03525	COG0754	glutathionylspermidine amidase activity
IB009_RS03535	COG1538	Outer membrane efflux protein
IB009_RS03540	COG0494	nUDIX hydrolase
IB009_RS03545	COG3151	Protein conserved in bacteria
IB009_RS03550	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IB009_RS03555	COG3150	esterase
IB009_RS03560	COG0187	DNA topoisomerase II activity
IB009_RS03565	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IB009_RS03570	COG2249	NAD(P)H dehydrogenase (quinone) activity
IB009_RS03580	COG0642	Histidine kinase
IB009_RS03585	COG0745	RESPONSE REGULATOR receiver
IB009_RS03590	COG3111	PFAM Bacterial OB fold (BOF) protein
IB009_RS03595	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
IB009_RS03600	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IB009_RS03605	COG0204	Acyl-transferase
IB009_RS03610	COG2132	Multicopper oxidase
IB009_RS03615	COG1032	radical SAM domain protein
IB009_RS03620	COG4238	major outer membrane lipoprotein
IB009_RS03630	COG0656	L-ascorbic acid biosynthetic process
IB009_RS03635	COG1979	alcohol dehydrogenase
IB009_RS03640	COG2207	Transcriptional regulator
IB009_RS03645	COG0586	Pfam SNARE associated Golgi protein
IB009_RS03650	COG0626	cystathionine gamma-synthase activity
IB009_RS03655	COG0811	peptide transport
IB009_RS03660	COG0848	biopolymer transport protein
IB009_RS03665	COG1028	Short-chain dehydrogenase reductase Sdr
IB009_RS03675	COG0667	Aldo Keto reductase
IB009_RS03690	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
IB009_RS03695	COG0437	4 iron, 4 sulfur cluster binding
IB009_RS03700	COG5557	Pfam Polysulphide reductase, NrfD
IB009_RS03705	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
IB009_RS03710	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IB009_RS03715	COG1773	rubredoxin
IB009_RS03725	COG0298	carbon dioxide binding
IB009_RS03730	COG0625	glutathione transferase activity
IB009_RS03735	COG0754	glutathionylspermidine amidase activity
IB009_RS03740	COG0306	phosphate transporter
IB009_RS03745	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IB009_RS03750	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IB009_RS03755	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IB009_RS03760	COG2244	polysaccharide biosynthetic process
IB009_RS03770	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
IB009_RS03775	COG0795	lipopolysaccharide-transporting ATPase activity
IB009_RS03785	COG0156	8-amino-7-oxononanoate synthase activity
IB009_RS03790	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IB009_RS03800	COG0318	PFAM AMP-dependent synthetase and ligase
IB009_RS03805	COG0456	acetyltransferase
IB009_RS03810	COG2186	Transcriptional regulator
IB009_RS03815	COG0277	FAD linked oxidase domain protein
IB009_RS03820	COG0277	FAD linked oxidase domain protein
IB009_RS03825	COG0247	lactate metabolic process
IB009_RS03830	COG3193	protein, possibly involved in utilization of glycolate and propanediol
IB009_RS03835	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IB009_RS03840	COG1620	l-lactate permease
IB009_RS03870	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IB009_RS03875	COG1459	type II secretion system
IB009_RS03880	COG2165	general secretion pathway protein
IB009_RS03910	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
IB009_RS03920	COG1811	Na channel or pump
IB009_RS03925	COG1982	Orn Lys Arg decarboxylase major
IB009_RS03930	COG2211	Major facilitator Superfamily
IB009_RS03945	COG1194	a g-specific adenine glycosylase
IB009_RS03955	COG3171	Protein conserved in bacteria
IB009_RS03965	COG0252	asparaginase activity
IB009_RS03980	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IB009_RS03985	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IB009_RS03990	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IB009_RS04005	COG0762	integral membrane protein
IB009_RS04010	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IB009_RS04015	COG2805	Type II/IV secretion system protein
IB009_RS04030	COG0189	ligase activity
IB009_RS04035	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IB009_RS04040	COG2356	endonuclease I
IB009_RS04050	COG2814	Major facilitator Superfamily
IB009_RS04070	COG1166	arginine decarboxylase activity
IB009_RS04080	COG0501	Belongs to the peptidase M48B family
IB009_RS04085	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IB009_RS04090	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IB009_RS04095	COG2213	PTS system mannitol-specific
IB009_RS04105	COG1494	fructose-1,6-bisphosphatase
IB009_RS04115	COG1072	(Pantothenic acid kinase))
IB009_RS04120	COG1122	ATPase activity
IB009_RS04125	COG1122	ATPase activity
IB009_RS04155	COG0191	fructose-bisphosphate aldolase activity
IB009_RS04160	COG0668	transmembrane transport
IB009_RS04165	COG1279	arginine transmembrane transporter activity
IB009_RS04170	COG2968	Membrane
IB009_RS04175	COG0583	DNA-binding transcription factor activity
IB009_RS04180	COG0427	acetyl-CoA hydrolase
IB009_RS04185	COG1024	Enoyl-CoA hydratase
IB009_RS04190	COG1703	isobutyryl-CoA mutase activity
IB009_RS04195	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IB009_RS04195	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IB009_RS04215	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IB009_RS04230	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IB009_RS04250	COG0006	proline dipeptidase activity
IB009_RS04255	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IB009_RS04260	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IB009_RS04285	COG1028	Short-chain dehydrogenase reductase Sdr
IB009_RS04290	COG2723	6-phospho-beta-galactosidase activity
IB009_RS04300	COG1272	protein, Hemolysin III
IB009_RS04310	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IB009_RS04320	COG0716	FMN binding
IB009_RS04325	COG4974	Belongs to the 'phage' integrase family
IB009_RS04330	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IB009_RS04335	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IB009_RS04360	COG4942	peptidase
IB009_RS04370	COG3387	PFAM Glycoside hydrolase 15-related
IB009_RS04470	COG3710	Transcriptional regulator
IB009_RS04470	COG0457	Tetratricopeptide repeat
IB009_RS04475	COG0457	Tetratricopeptide repeat
IB009_RS04500	COG3710	Transcriptional regulator
IB009_RS04505	COG2771	luxR family
IB009_RS04510	COG0814	amino acid
IB009_RS04515	COG0183	Belongs to the thiolase family
IB009_RS04525	COG1028	Short-chain dehydrogenase reductase Sdr
IB009_RS04530	COG2814	Major facilitator Superfamily
IB009_RS04535	COG1794	racemase activity, acting on amino acids and derivatives
IB009_RS04540	COG0583	DNA-binding transcription factor activity
IB009_RS04550	COG1609	Transcriptional regulator
IB009_RS04565	COG0667	Aldo Keto reductase
IB009_RS04575	COG0861	Integral membrane protein TerC family
IB009_RS04590	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
IB009_RS04605	COG2165	general secretion pathway protein
IB009_RS04610	COG4795	General secretion pathway protein
IB009_RS04620	COG4967	type IV pilus modification protein PilV
IB009_RS04625	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IB009_RS04630	COG1025	Belongs to the peptidase M16 family
IB009_RS04635	COG1074	ATP-dependent DNA helicase activity
IB009_RS04640	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IB009_RS04645	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IB009_RS04645	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IB009_RS04650	COG0860	N-Acetylmuramoyl-L-alanine amidase
IB009_RS04710	COG1484	DNA-dependent DNA replication
IB009_RS04715	COG4584	PFAM Integrase catalytic
IB009_RS04750	COG2885	chlorophyll binding
IB009_RS04790	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
IB009_RS04795	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IB009_RS04800	COG2166	iron-sulfur cluster assembly
IB009_RS04805	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IB009_RS04815	COG0583	DNA-binding transcription factor activity
IB009_RS04820	COG2363	Small membrane protein
IB009_RS04830	COG1349	DNA-binding transcription factor activity
IB009_RS04840	COG1070	Carbohydrate kinase
IB009_RS04850	COG0738	Major facilitator superfamily
IB009_RS04855	COG0235	Class ii aldolase
IB009_RS04860	COG1454	alcohol dehydrogenase
IB009_RS04870	COG1760	l-serine dehydratase
IB009_RS04875	COG0814	amino acid
IB009_RS04880	COG1611	Belongs to the LOG family
IB009_RS04895	COG3098	single-species biofilm formation
IB009_RS04900	COG0564	pseudouridine synthase activity
IB009_RS04905	COG0716	FMN binding
IB009_RS04910	COG2271	Major facilitator Superfamily
IB009_RS04915	COG4948	Mandelate Racemase Muconate Lactonizing
IB009_RS04920	COG4948	Mandelate Racemase Muconate Lactonizing
IB009_RS04925	COG3850	Histidine kinase
IB009_RS04925	COG3437	response regulator, receiver
IB009_RS04925	COG2205	protein histidine kinase activity
IB009_RS04925	COG4999	Histidine kinase
IB009_RS04935	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IB009_RS04940	COG2336	PFAM SpoVT AbrB
IB009_RS04945	COG2337	Toxic component of a toxin-antitoxin (TA) module
IB009_RS04950	COG3956	TIGRFAM MazG family protein
IB009_RS04970	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IB009_RS04980	COG0602	queuosine metabolic process
IB009_RS04985	COG1070	Carbohydrate kinase
IB009_RS04990	COG0720	synthase
IB009_RS05015	COG1203	CRISPR-associated helicase, Cas3
IB009_RS05030	COG1857	crispr-associated protein
IB009_RS05045	COG1518	maintenance of DNA repeat elements
IB009_RS05050	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IB009_RS05055	COG2234	aminopeptidase activity
IB009_RS05110	COG4942	peptidase
IB009_RS05110	COG1388	LysM domain
IB009_RS05115	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IB009_RS05130	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IB009_RS05140	COG2610	gluconate transmembrane transporter activity
IB009_RS05145	COG3622	Belongs to the hyi family
IB009_RS05150	COG0235	Class ii aldolase
IB009_RS05155	COG3395	kinase activity
IB009_RS05160	COG2084	Dehydrogenase
IB009_RS05165	COG1349	DNA-binding transcription factor activity
IB009_RS05170	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IB009_RS05190	COG3604	Transcriptional regulator
IB009_RS05195	COG0309	Hydrogenase expression formation protein (HypE)
IB009_RS05200	COG0409	Hydrogenase expression formation protein
IB009_RS05205	COG0298	carbon dioxide binding
IB009_RS05210	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IB009_RS05215	COG0375	protein maturation
IB009_RS05225	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IB009_RS05230	COG0651	ATP synthesis coupled electron transport
IB009_RS05235	COG0650	Formate hydrogenlyase subunit 4
IB009_RS05240	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
IB009_RS05240	COG3261	NADH dehydrogenase
IB009_RS05245	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IB009_RS05250	COG3260	NADH ubiquinone oxidoreductase 20
IB009_RS05260	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IB009_RS05270	COG5499	transcription regulator containing HTH domain
IB009_RS05275	COG2723	6-phospho-beta-galactosidase activity
IB009_RS05280	COG1263	PTS System
IB009_RS05280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IB009_RS05285	COG1609	Transcriptional regulator
IB009_RS05290	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IB009_RS05295	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
IB009_RS05320	COG1349	DNA-binding transcription factor activity
IB009_RS05325	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
IB009_RS05330	COG1028	Short-chain dehydrogenase reductase Sdr
IB009_RS05340	COG3732	PTS system glucitol sorbitol-specific
IB009_RS05345	COG3730	PTS system glucitol sorbitol-specific
IB009_RS05350	COG2951	lytic endotransglycosylase activity
IB009_RS05355	COG1546	Belongs to the CinA family
IB009_RS05375	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IB009_RS05405	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IB009_RS05410	COG1238	metal cluster binding
IB009_RS05425	COG2814	Major facilitator Superfamily
IB009_RS05430	COG1566	PFAM secretion protein HlyD family protein
IB009_RS05435	COG1846	Transcriptional regulator
IB009_RS05445	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IB009_RS05450	COG2814	Major facilitator Superfamily
IB009_RS05455	COG2113	Glycine betaine
IB009_RS05460	COG4176	ABC-type proline glycine betaine transport system permease component
IB009_RS05465	COG4175	Glycine betaine
IB009_RS05470	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IB009_RS05475	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IB009_RS05485	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IB009_RS05490	COG4575	ribosome binding
IB009_RS05505	COG2916	Histone family protein nucleoid-structuring protein H-NS
IB009_RS05510	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IB009_RS05515	COG0640	Transcriptional regulator
IB009_RS05520	COG0401	homolog of Blt101
IB009_RS05525	COG1652	LysM domain
IB009_RS05530	COG1802	Transcriptional regulator
IB009_RS05535	COG1113	amino acid transport
IB009_RS05540	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IB009_RS05545	COG1012	belongs to the aldehyde dehydrogenase family
IB009_RS05550	COG0579	oxidoreductase
IB009_RS05585	COG0582	viral genome integration into host DNA
IB009_RS05605	COG0582	viral genome integration into host DNA
IB009_RS05620	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
IB009_RS05625	COG5532	Uncharacterized conserved protein (DUF2303)
IB009_RS05670	COG1846	Transcriptional regulator
IB009_RS05680	COG4725	Belongs to the MT-A70-like family
IB009_RS05690	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
IB009_RS05700	COG1403	HNH endonuclease
IB009_RS05735	COG5562	phage envelope protein
IB009_RS05745	COG4220	transposase activity
IB009_RS05765	COG1030	water channel activity
IB009_RS05815	COG1196	nuclear chromosome segregation
IB009_RS05850	COG5301	cellulose 1,4-beta-cellobiosidase activity
IB009_RS05885	COG2867	negative regulation of translational initiation
IB009_RS05895	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IB009_RS05900	COG0497	DNA recombination
IB009_RS05915	COG4536	flavin adenine dinucleotide binding
IB009_RS05920	COG4137	Cytochrome C assembly protein
IB009_RS05925	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IB009_RS05950	COG2885	chlorophyll binding
IB009_RS05955	COG2199	diguanylate cyclase activity
IB009_RS05970	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IB009_RS05975	COG1605	Chorismate mutase
IB009_RS05975	COG0287	Prephenate dehydrogenase
IB009_RS05980	COG0077	Prephenate dehydratase
IB009_RS05980	COG1605	Chorismate mutase
IB009_RS05990	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IB009_RS05995	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IB009_RS06000	COG0564	pseudouridine synthase activity
IB009_RS06005	COG1496	oxidoreductase activity
IB009_RS06010	COG0542	response to heat
IB009_RS06035	COG0477	Major facilitator Superfamily
IB009_RS06040	COG5544	Lipoprotein
IB009_RS06045	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IB009_RS06050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IB009_RS06050	COG1042	CoA-binding domain protein
IB009_RS06050	COG0045	succinate-CoA ligase (ADP-forming) activity
IB009_RS06055	COG3148	PFAM DTW domain containing protein
IB009_RS06060	COG3118	belongs to the thioredoxin family
IB009_RS06065	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IB009_RS06085	COG0583	DNA-binding transcription factor activity
IB009_RS06090	COG0513	Belongs to the DEAD box helicase family
IB009_RS06100	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
IB009_RS06110	COG1595	DNA-templated transcription, initiation
IB009_RS06115	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
IB009_RS06120	COG3026	antisigma factor binding
IB009_RS06125	COG3086	response to oxidative stress
IB009_RS06135	COG0681	Belongs to the peptidase S26 family
IB009_RS06155	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IB009_RS06170	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IB009_RS06175	COG1737	Transcriptional regulator
IB009_RS06180	COG0560	Phosphoserine phosphatase
IB009_RS06200	COG2205	protein histidine kinase activity
IB009_RS06205	COG3170	Tfp pilus assembly protein FimV
IB009_RS06210	COG2204	response regulator
IB009_RS06215	COG0347	Belongs to the P(II) protein family
IB009_RS06220	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IB009_RS06220	COG1017	nitric oxide dioxygenase activity
IB009_RS06230	COG1940	carbohydrate kinase activity
IB009_RS06235	COG0457	Tetratricopeptide repeat
IB009_RS06240	COG1879	ABC-type sugar transport system periplasmic component
IB009_RS06245	COG1129	ABC transporter
IB009_RS06250	COG1172	Belongs to the binding-protein-dependent transport system permease family
IB009_RS06255	COG1063	alcohol dehydrogenase
IB009_RS06260	COG2017	converts alpha-aldose to the beta-anomer
IB009_RS06265	COG2259	Doxx family
IB009_RS06290	COG4638	Rieske (2fe-2S)
IB009_RS06295	COG0583	DNA-binding transcription factor activity
IB009_RS06300	COG2814	Major facilitator Superfamily
IB009_RS06305	COG3711	transcriptional antiterminator
IB009_RS06310	COG1073	alpha beta
IB009_RS06315	COG0483	inositol monophosphate 1-phosphatase activity
IB009_RS06335	COG0822	iron-sulfur transferase activity
IB009_RS06355	COG0633	Ferredoxin
IB009_RS06360	COG2975	iron-sulfur cluster assembly
IB009_RS06375	COG2897	thiosulfate sulfurtransferase activity
IB009_RS06380	COG2373	Large extracellular alpha-helical protein
IB009_RS06385	COG4953	penicillin-binding protein 1C
IB009_RS06415	COG2976	Protein conserved in bacteria
IB009_RS06430	COG1645	bacterial-type flagellum-dependent swarming motility
IB009_RS06440	COG0516	GMP reductase activity
IB009_RS06440	COG0517	IMP dehydrogenase activity
IB009_RS06455	COG3133	Outer membrane lipoprotein
IB009_RS06470	COG2200	EAL domain
IB009_RS06475	COG0248	Ppx GppA phosphatase
IB009_RS06480	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IB009_RS06485	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IB009_RS06500	COG2233	PERMEase
IB009_RS06510	COG1393	Belongs to the ArsC family
IB009_RS06515	COG4783	chaperone-mediated protein folding
IB009_RS06520	COG0628	permease
IB009_RS06525	COG2116	formate transmembrane transporter activity
IB009_RS06530	COG2116	formate transmembrane transporter activity
IB009_RS06535	COG3604	Transcriptional regulator
IB009_RS06545	COG3260	NADH ubiquinone oxidoreductase 20
IB009_RS06550	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IB009_RS06560	COG0651	ATP synthesis coupled electron transport
IB009_RS06565	COG4237	Hydrogenase 4 membrane
IB009_RS06570	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IB009_RS06575	COG0650	Formate hydrogenlyase subunit 4
IB009_RS06585	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IB009_RS06590	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IB009_RS06595	COG2716	regulation of RNA biosynthetic process
IB009_RS06605	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
IB009_RS06625	COG2321	neutral zinc metallopeptidase
IB009_RS06635	COG0400	carboxylic ester hydrolase activity
IB009_RS06640	COG3547	Transposase (IS116 IS110 IS902 family)
IB009_RS06655	COG1393	Belongs to the ArsC family
IB009_RS06665	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IB009_RS06670	COG3850	Histidine kinase
IB009_RS06675	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IB009_RS06675	COG0493	'glutamate synthase
IB009_RS06685	COG5342	invasion associated locus B
IB009_RS06690	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IB009_RS06695	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IB009_RS06700	COG0281	malic enzyme
IB009_RS06700	COG0280	phosphate acetyltransferase
IB009_RS06705	COG4810	utilization protein
IB009_RS06710	COG4917	ethanolamine utilization protein
IB009_RS06715	COG4766	ethanolamine catabolic process
IB009_RS06720	COG4812	Cobalamin adenosyltransferase
IB009_RS06725	COG0280	phosphate acetyltransferase
IB009_RS06730	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
IB009_RS06735	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
IB009_RS06740	COG1012	belongs to the aldehyde dehydrogenase family
IB009_RS06745	COG4820	ethanolamine utilization protein (EutJ)
IB009_RS06750	COG1454	alcohol dehydrogenase
IB009_RS06755	COG3192	ethanolamine utilization protein
IB009_RS06760	COG4819	ethanolamine utilization protein
IB009_RS06770	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IB009_RS06775	COG0531	amino acid
IB009_RS06780	COG0076	glutamate decarboxylase activity
IB009_RS06785	COG0076	glutamate decarboxylase activity
IB009_RS06825	COG0582	viral genome integration into host DNA
IB009_RS06830	COG4303	Ethanolamine ammonia lyase large subunit
IB009_RS06840	COG4816	utilization protein
IB009_RS06845	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
IB009_RS06850	COG2207	Transcriptional regulator
IB009_RS06860	COG0860	N-Acetylmuramoyl-L-alanine amidase
IB009_RS06880	COG2837	iron assimilation
IB009_RS06885	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IB009_RS06890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IB009_RS06890	COG1263	PTS System
IB009_RS06905	COG1028	Short-chain dehydrogenase reductase Sdr
IB009_RS06910	COG4150	thiosulfate binding
IB009_RS06915	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IB009_RS06920	COG4208	sulfate ABC transporter
IB009_RS06925	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IB009_RS06930	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IB009_RS06945	COG2190	(PTS) system
IB009_RS06950	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IB009_RS06955	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IB009_RS06960	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IB009_RS06980	COG3530	Putative quorum-sensing-regulated virulence factor
IB009_RS06985	COG0385	Bile acid
IB009_RS06990	COG0583	DNA-binding transcription factor activity
IB009_RS07000	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IB009_RS07005	COG2211	Major facilitator Superfamily
IB009_RS07015	COG0583	DNA-binding transcription factor activity
IB009_RS07050	COG3415	Transposase
IB009_RS07055	COG3415	Transposase
IB009_RS07070	COG2200	EAL domain
IB009_RS07070	COG2199	diguanylate cyclase activity
IB009_RS07075	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IB009_RS07100	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IB009_RS07105	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IB009_RS07110	COG0006	proline dipeptidase activity
IB009_RS07115	COG1363	Peptidase, m42
IB009_RS07125	COG2207	Transcriptional regulator
IB009_RS07130	COG3279	Response regulator of the LytR AlgR family
IB009_RS07135	COG3275	phosphorelay sensor kinase activity
IB009_RS07140	COG0436	Aminotransferase
IB009_RS07150	COG1560	Kdo2-lipid A biosynthetic process
IB009_RS07175	COG0028	Belongs to the TPP enzyme family
IB009_RS07180	COG0679	Auxin Efflux Carrier
IB009_RS07185	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IB009_RS07190	COG0784	Response regulator, receiver
IB009_RS07190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IB009_RS07190	COG2205	protein histidine kinase activity
IB009_RS07190	COG2198	Histidine kinase
IB009_RS07195	COG2197	response regulator
IB009_RS07200	COG1566	PFAM secretion protein HlyD family protein
IB009_RS07205	COG0477	Major facilitator Superfamily
IB009_RS07245	COG2116	formate transmembrane transporter activity
IB009_RS07250	COG2853	Lipoprotein
IB009_RS07260	COG2067	long-chain fatty acid transport protein
IB009_RS07265	COG3691	Protein conserved in bacteria
IB009_RS07280	COG2062	phosphohistidine phosphatase, SixA
IB009_RS07285	COG3539	Fimbrial protein
IB009_RS07290	COG3188	usher protein
IB009_RS07295	COG3121	Chaperone
IB009_RS07300	COG3539	Fimbrial protein
IB009_RS07305	COG3539	Fimbrial protein
IB009_RS07310	COG3539	Fimbrial protein
IB009_RS07340	COG0730	response to heat
IB009_RS07345	COG3101	peptidyl-lysine hydroxylation
IB009_RS07360	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IB009_RS07365	COG2814	Major facilitator Superfamily
IB009_RS07380	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IB009_RS07390	COG0586	Pfam SNARE associated Golgi protein
IB009_RS07400	COG0285	dihydrofolate synthase activity
IB009_RS07405	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
IB009_RS07410	COG1286	toxin biosynthetic process
IB009_RS07415	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IB009_RS07420	COG0163	prenyltransferase activity
IB009_RS07425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IB009_RS07430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IB009_RS07435	COG4215	(ABC) transporter
IB009_RS07440	COG4160	amino acid transport
IB009_RS07445	COG4598	ABC transporter
IB009_RS07450	COG5464	transposase or invertase
IB009_RS07455	COG1090	epimerase
IB009_RS07460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IB009_RS07465	COG0625	glutathione transferase activity
IB009_RS07470	COG0625	glutathione transferase activity
IB009_RS07475	COG0622	Phosphoesterase
IB009_RS07480	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
IB009_RS07485	COG1288	antiporter activity
IB009_RS07490	COG0857	belongs to the CobB CobQ family
IB009_RS07490	COG0280	phosphate acetyltransferase
IB009_RS07495	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IB009_RS07510	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IB009_RS07515	COG0471	metal ion transport
IB009_RS07515	COG0490	domain, Protein
IB009_RS07525	COG0436	Aminotransferase
IB009_RS07530	COG0583	DNA-binding transcription factor activity
IB009_RS07550	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
IB009_RS07555	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IB009_RS07560	COG1034	ATP synthesis coupled electron transport
IB009_RS07575	COG0839	Belongs to the complex I subunit 6 family
IB009_RS07585	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IB009_RS07590	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IB009_RS07620	COG2153	protein acetylation
IB009_RS07625	COG4575	ribosome binding
IB009_RS07630	COG1169	isochorismate synthase
IB009_RS07645	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IB009_RS07655	COG0318	PFAM AMP-dependent synthetase and ligase
IB009_RS07735	COG5464	transposase or invertase
IB009_RS07740	COG0247	lactate metabolic process
IB009_RS07750	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IB009_RS07760	COG0584	glycerophosphoryl diester phosphodiesterase
IB009_RS07770	COG3642	lipopolysaccharide core region biosynthetic process
IB009_RS07775	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IB009_RS07780	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IB009_RS07785	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IB009_RS07790	COG3468	outer membrane autotransporter barrel domain protein
IB009_RS07800	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IB009_RS07805	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
IB009_RS07810	COG3234	Protein of unknown function (DUF1175)
IB009_RS07815	COG2373	Large extracellular alpha-helical protein
IB009_RS07820	COG5445	Predicted secreted protein (DUF2300)
IB009_RS07825	COG4676	Protein conserved in bacteria
IB009_RS07830	COG0183	Belongs to the thiolase family
IB009_RS07835	COG2031	fatty acid transporter
IB009_RS07840	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IB009_RS07845	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IB009_RS07850	COG2204	response regulator
IB009_RS07855	COG3852	Histidine kinase
IB009_RS07860	COG2205	protein histidine kinase activity
IB009_RS07860	COG0784	Response regulator, receiver
IB009_RS07865	COG2197	response regulator
IB009_RS07870	COG0642	Histidine kinase
IB009_RS07870	COG2198	Histidine kinase
IB009_RS07875	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IB009_RS07880	COG1477	protein flavinylation
IB009_RS07885	COG2169	Transcriptional regulator
IB009_RS07885	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IB009_RS07890	COG3145	DNA-N1-methyladenine dioxygenase activity
IB009_RS07895	COG4615	Cyclic peptide transporter
IB009_RS07915	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IB009_RS07915	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
IB009_RS07920	COG3062	negative regulation of establishment of protein localization
IB009_RS07930	COG0437	4 iron, 4 sulfur cluster binding
IB009_RS07935	COG0348	domain, Protein
IB009_RS07940	COG3043	anaerobic respiration
IB009_RS07945	COG3005	denitrification pathway
IB009_RS07950	COG4133	protoheme IX ABC transporter activity
IB009_RS07955	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IB009_RS07960	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IB009_RS07965	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IB009_RS07975	COG1138	Cytochrome C-type biogenesis protein
IB009_RS07980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IB009_RS07985	COG4235	cytochrome complex assembly
IB009_RS07985	COG3088	subunit of a heme lyase
IB009_RS07990	COG2197	response regulator
IB009_RS07995	COG3468	outer membrane autotransporter barrel domain protein
IB009_RS08005	COG3083	sulfuric ester hydrolase activity
IB009_RS08025	COG1061	Type III restriction enzyme res subunit
IB009_RS08030	COG1187	pseudouridine synthase activity
IB009_RS08035	COG2814	Major facilitator Superfamily
IB009_RS08045	COG4172	Belongs to the ABC transporter superfamily
IB009_RS08050	COG4239	(ABC) transporter, permease
IB009_RS08055	COG4174	ABC transporter (Permease)
IB009_RS08060	COG4166	transmembrane transport
IB009_RS08065	COG2200	EAL domain
IB009_RS08070	COG0791	NLP P60 protein
IB009_RS08075	COG0671	phosphoesterase, PA-phosphatase related
IB009_RS08080	COG0523	cobalamin synthesis protein
IB009_RS08085	COG0246	Mannitol dehydrogenase
IB009_RS08100	COG2814	Major facilitator Superfamily
IB009_RS08105	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IB009_RS08105	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IB009_RS08110	COG1105	Belongs to the carbohydrate kinase PfkB family
IB009_RS08115	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IB009_RS08115	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IB009_RS08115	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IB009_RS08120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IB009_RS08125	COG2313	pseudouridylate synthase activity
IB009_RS08130	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IB009_RS08135	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IB009_RS08145	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IB009_RS08150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IB009_RS08150	COG1522	sequence-specific DNA binding
IB009_RS08160	COG2855	membrane
IB009_RS08165	COG0583	DNA-binding transcription factor activity
IB009_RS08170	COG0833	amino acid
IB009_RS08175	COG4771	TonB-dependent receptor
IB009_RS08190	COG2311	Membrane
IB009_RS08195	COG1609	Transcriptional regulator
IB009_RS08200	COG1879	ABC-type sugar transport system periplasmic component
IB009_RS08205	COG1129	ABC transporter
IB009_RS08210	COG4211	Belongs to the binding-protein-dependent transport system permease family
IB009_RS08215	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IB009_RS08215	COG0167	dihydroorotate dehydrogenase activity
IB009_RS08220	COG0493	'glutamate synthase
IB009_RS08230	COG2949	membrane
IB009_RS08240	COG1346	cytolysis
IB009_RS08250	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IB009_RS08265	COG1028	Short-chain dehydrogenase reductase Sdr
IB009_RS08270	COG0586	Pfam SNARE associated Golgi protein
IB009_RS08280	COG1686	Belongs to the peptidase S11 family
IB009_RS08285	COG0277	FAD linked oxidase domain protein
IB009_RS08290	COG1472	Belongs to the glycosyl hydrolase 3 family
IB009_RS08295	COG1732	Glycine betaine
IB009_RS08300	COG1174	glycine betaine transport
IB009_RS08305	COG1125	glycine betaine transport
IB009_RS08310	COG1174	glycine betaine transport
IB009_RS08320	COG0789	Transcriptional regulator
IB009_RS08325	COG3275	phosphorelay sensor kinase activity
IB009_RS08330	COG3279	Response regulator of the LytR AlgR family
IB009_RS08335	COG4807	Protein conserved in bacteria
IB009_RS08340	COG4808	Protein conserved in bacteria
IB009_RS08360	COG0489	protein tyrosine kinase activity
IB009_RS08370	COG3539	Fimbrial protein
IB009_RS08375	COG3121	Chaperone
IB009_RS08380	COG3188	usher protein
IB009_RS08385	COG3539	Fimbrial protein
IB009_RS08390	COG5455	response to cobalt ion
IB009_RS08410	COG0351	phosphomethylpyrimidine kinase
IB009_RS08415	COG3757	hydrolase, family 25
IB009_RS08420	COG2188	Transcriptional regulator
IB009_RS08425	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IB009_RS08430	COG1397	ADP-ribosylglycohydrolase
IB009_RS08435	COG2211	Major facilitator Superfamily
IB009_RS08440	COG1830	Aldolase
IB009_RS08485	COG0826	peptidase U32
IB009_RS08500	COG0745	RESPONSE REGULATOR receiver
IB009_RS08505	COG2205	protein histidine kinase activity
IB009_RS08545	COG4245	von Willebrand factor, type A
IB009_RS08550	COG0631	protein serine/threonine phosphatase activity
IB009_RS08560	COG0443	Heat shock 70 kDa protein
IB009_RS08565	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IB009_RS08575	COG0572	uridine kinase
IB009_RS08585	COG2982	Protein involved in outer membrane biogenesis
IB009_RS08590	COG1253	flavin adenine dinucleotide binding
IB009_RS08645	COG0438	transferase activity, transferring glycosyl groups
IB009_RS08670	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IB009_RS08700	COG1088	dTDP-glucose 4,6-dehydratase activity
IB009_RS08735	COG0140	phosphoribosyl-ATP diphosphatase activity
IB009_RS08735	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IB009_RS08750	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IB009_RS08755	COG0131	Imidazoleglycerol-phosphate dehydratase
IB009_RS08755	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IB009_RS08780	COG2161	toxin-antitoxin pair type II binding
IB009_RS08785	COG4115	mRNA cleavage
IB009_RS08790	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IB009_RS08795	COG0583	DNA-binding transcription factor activity
IB009_RS08805	COG0531	amino acid
IB009_RS08810	COG2391	methyltransferase activity
IB009_RS08815	COG0425	Belongs to the sulfur carrier protein TusA family
IB009_RS08820	COG2925	Exonuclease
IB009_RS08825	COG1686	Belongs to the peptidase S11 family
IB009_RS08835	COG1289	transmembrane transporter activity
IB009_RS08860	COG3436	PFAM IS66 Orf2 family protein
IB009_RS08865	COG4372	Transposase
IB009_RS08870	COG4584	PFAM Integrase catalytic
IB009_RS08875	COG1484	DNA-dependent DNA replication
IB009_RS08900	COG2003	Belongs to the UPF0758 family
IB009_RS08920	COG3468	outer membrane autotransporter barrel domain protein
IB009_RS08985	COG2826	transposase and inactivated derivatives, IS30 family
IB009_RS08995	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
IB009_RS09010	COG1376	ErfK ybiS ycfS ynhG family protein
IB009_RS09020	COG0583	DNA-binding transcription factor activity
IB009_RS09025	COG0583	DNA-binding transcription factor activity
IB009_RS09050	COG0217	transcriptional regulatory protein
IB009_RS09055	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IB009_RS09060	COG0477	Major facilitator Superfamily
IB009_RS09070	COG1470	cell adhesion involved in biofilm formation
IB009_RS09070	COG1388	LysM domain
IB009_RS09120	COG2351	hydroxyisourate hydrolase activity
IB009_RS09125	COG0745	RESPONSE REGULATOR receiver
IB009_RS09130	COG2205	protein histidine kinase activity
IB009_RS09140	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IB009_RS09150	COG1418	mRNA catabolic process
IB009_RS09155	COG0270	DNA (cytosine-5-)-methyltransferase activity
IB009_RS09160	COG3727	T/G mismatch-specific endonuclease activity
IB009_RS09165	COG0697	spore germination
IB009_RS09170	COG2354	Protein conserved in bacteria
IB009_RS09175	COG5475	Uncharacterized small protein (DUF2158)
IB009_RS09200	COG2197	response regulator
IB009_RS09205	COG1684	flagellar biosynthetic protein fliR
IB009_RS09210	COG1987	bacterial-type flagellum assembly
IB009_RS09215	COG1338	Plays a role in the flagellum-specific transport system
IB009_RS09220	COG3190	flagellar
IB009_RS09225	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IB009_RS09230	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IB009_RS09235	COG1580	Controls the rotational direction of flagella during chemotaxis
IB009_RS09240	COG3144	bacterial-type flagellum assembly
IB009_RS09245	COG2882	bacterial-type flagellum organization
IB009_RS09250	COG1157	protein secretion by the type III secretion system
IB009_RS09255	COG1317	bacterial-type flagellum organization
IB009_RS09260	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IB009_RS09265	COG1766	The M ring may be actively involved in energy transduction
IB009_RS09275	COG2076	Multidrug Resistance protein
IB009_RS09280	COG1881	PFAM PEBP family protein
IB009_RS09285	COG2207	Transcriptional regulator
IB009_RS09305	COG0675	Transposase, IS605 OrfB family
IB009_RS09310	COG2135	peptidase activity
IB009_RS09315	COG0425	Belongs to the sulfur carrier protein TusA family
IB009_RS09320	COG2391	methyltransferase activity
IB009_RS09330	COG0366	Alpha amylase catalytic
IB009_RS09340	COG1516	flagellar protein fliS
IB009_RS09345	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IB009_RS09350	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IB009_RS09355	COG1191	sigma factor activity
IB009_RS09365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IB009_RS09375	COG0765	amino acid transport
IB009_RS09380	COG1126	abc transporter atp-binding protein
IB009_RS09385	COG2197	response regulator
IB009_RS09400	COG2197	response regulator
IB009_RS09430	COG3012	SEC-C Motif Domain Protein
IB009_RS09430	COG3318	Belongs to the UPF0149 family
IB009_RS09435	COG0814	amino acid
IB009_RS09445	COG1528	Iron-storage protein
IB009_RS09465	COG1528	Iron-storage protein
IB009_RS09470	COG1879	ABC-type sugar transport system periplasmic component
IB009_RS09475	COG1129	ABC transporter
IB009_RS09480	COG1172	Belongs to the binding-protein-dependent transport system permease family
IB009_RS09485	COG1877	trehalose-phosphatase activity
IB009_RS09495	COG0589	response to stress
IB009_RS09510	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IB009_RS09515	COG1360	Flagellar Motor Protein
IB009_RS09520	COG0643	Histidine kinase
IB009_RS09520	COG2198	Histidine kinase
IB009_RS09525	COG0835	chemotaxis
IB009_RS09530	COG0840	transmembrane signaling receptor activity
IB009_RS09535	COG0840	transmembrane signaling receptor activity
IB009_RS09540	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IB009_RS09545	COG2201	protein-glutamate methylesterase activity
IB009_RS09550	COG0745	RESPONSE REGULATOR receiver
IB009_RS09555	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
IB009_RS09560	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IB009_RS09565	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IB009_RS09575	COG3755	Protein conserved in bacteria
IB009_RS09585	COG3102	Protein conserved in bacteria
IB009_RS09595	COG3005	denitrification pathway
IB009_RS09600	COG0243	molybdopterin cofactor binding
IB009_RS09615	COG3788	relative of glutathione S-transferase, MAPEG superfamily
IB009_RS09620	COG1801	Protein of unknown function DUF72
IB009_RS09675	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IB009_RS09680	COG1801	Protein of unknown function DUF72
IB009_RS09685	COG1335	isochorismatase
IB009_RS09695	COG0494	nUDIX hydrolase
IB009_RS09700	COG0217	transcriptional regulatory protein
IB009_RS09730	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IB009_RS09740	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
IB009_RS09745	COG0739	heme binding
IB009_RS09750	COG1560	Kdo2-lipid A biosynthetic process
IB009_RS09755	COG0469	pyruvate kinase activity
IB009_RS09760	COG1737	Transcriptional regulator
IB009_RS09765	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IB009_RS09770	COG0129	dihydroxy-acid dehydratase activity
IB009_RS09775	COG0800	Aldolase
IB009_RS09785	COG3141	response to X-ray
IB009_RS09795	COG2979	Protein of unknown function (DUF533)
IB009_RS09800	COG1770	oligopeptidase
IB009_RS09805	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IB009_RS09810	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IB009_RS09820	COG2372	response to copper ion
IB009_RS09825	COG1276	copper resistance
IB009_RS09835	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IB009_RS09855	COG3008	intermembrane lipid transfer
IB009_RS09860	COG2995	paraquat-inducible protein a
IB009_RS09865	COG1956	GAF domain-containing protein
IB009_RS09875	COG0793	Belongs to the peptidase S41A family
IB009_RS09885	COG2814	Major facilitator Superfamily
IB009_RS09890	COG1414	Transcriptional regulator
IB009_RS09920	COG2226	methyltransferase
IB009_RS09935	COG3716	PTS system mannose fructose sorbose family IID component
IB009_RS09940	COG3715	PTS system
IB009_RS09945	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IB009_RS09945	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
IB009_RS09950	COG1253	flavin adenine dinucleotide binding
IB009_RS09955	COG2200	EAL domain
IB009_RS09960	COG1760	l-serine dehydratase
IB009_RS09970	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IB009_RS09985	COG0251	oxidation-reduction process
IB009_RS09990	COG1199	ATP-dependent helicase activity
IB009_RS09995	COG1214	PFAM Peptidase M22, glycoprotease
IB009_RS10000	COG3065	identical protein binding
IB009_RS10005	COG0318	PFAM AMP-dependent synthetase and ligase
IB009_RS10010	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
IB009_RS10015	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IB009_RS10020	COG4638	Rieske (2fe-2S)
IB009_RS10025	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IB009_RS10030	COG0473	3-isopropylmalate dehydrogenase activity
IB009_RS10035	COG0583	DNA-binding transcription factor activity
IB009_RS10050	COG0675	Transposase, IS605 OrfB family
IB009_RS10055	COG2261	transglycosylase associated protein
IB009_RS10070	COG2203	Gaf domain
IB009_RS10070	COG2199	diguanylate cyclase activity
IB009_RS10075	COG3042	response to heat
IB009_RS10080	COG3189	MarR family transcriptional regulator
IB009_RS10085	COG2807	transmembrane transport
IB009_RS10090	COG2207	Transcriptional regulator
IB009_RS10105	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IB009_RS10110	COG2199	diguanylate cyclase activity
IB009_RS10115	COG2199	diguanylate cyclase activity
IB009_RS10125	COG2766	serine protein kinase
IB009_RS10130	COG3713	MltA-interacting MipA family protein
IB009_RS10135	COG0656	L-ascorbic acid biosynthetic process
IB009_RS10140	COG0676	glucose-6-phosphate 1-epimerase activity
IB009_RS10145	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IB009_RS10155	COG3139	Protein of unknown function (DUF1315)
IB009_RS10160	COG1335	isochorismatase
IB009_RS10165	COG0252	asparaginase activity
IB009_RS10170	COG0616	signal peptide processing
IB009_RS10175	COG0778	Nitroreductase
IB009_RS10185	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IB009_RS10195	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IB009_RS10205	COG0494	nUDIX hydrolase
IB009_RS10210	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IB009_RS10215	COG2897	thiosulfate sulfurtransferase activity
IB009_RS10220	COG4136	ATPase activity
IB009_RS10225	COG4135	transport system, permease component
IB009_RS10230	COG4134	Bacterial extracellular solute-binding protein
IB009_RS10235	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IB009_RS10240	COG0398	Pfam SNARE associated Golgi protein
IB009_RS10250	COG0398	Pfam SNARE associated Golgi protein
IB009_RS10255	COG0708	Exodeoxyribonuclease III
IB009_RS10285	COG3678	ATP-independent chaperone mediated protein folding
IB009_RS10295	COG0322	excinuclease ABC activity
IB009_RS10305	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IB009_RS10310	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IB009_RS10315	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IB009_RS10320	COG1447	Phosphotransferase system cellobiose-specific component IIA
IB009_RS10325	COG2169	Transcriptional regulator
IB009_RS10325	COG1917	Cupin 2, conserved barrel domain protein
IB009_RS10330	COG1486	melibiose metabolic process
IB009_RS10340	COG0753	catalase activity
IB009_RS10355	COG1823	symporter activity
IB009_RS10360	COG1988	membrane-bound metal-dependent
IB009_RS10365	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IB009_RS10375	COG3001	Fructosamine kinase
IB009_RS10385	COG1105	Belongs to the carbohydrate kinase PfkB family
IB009_RS10390	COG3137	Salt-induced outer membrane protein
IB009_RS10435	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IB009_RS10435	COG0072	phenylalanine-tRNA ligase activity
IB009_RS10450	COG0386	Belongs to the glutathione peroxidase family
IB009_RS10460	COG0791	NLP P60 protein
IB009_RS10465	COG2200	EAL domain
IB009_RS10475	COG4256	Hemin uptake protein
IB009_RS10480	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IB009_RS10490	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IB009_RS10490	COG0574	Belongs to the PEP-utilizing enzyme family
IB009_RS10495	COG0318	PFAM AMP-dependent synthetase and ligase
IB009_RS10500	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IB009_RS10505	COG0644	oxidoreductase
IB009_RS10510	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
IB009_RS10515	COG2086	electron transfer activity
IB009_RS10520	COG2207	Transcriptional regulator
IB009_RS10520	COG1917	Cupin 2, conserved barrel domain protein
IB009_RS10525	COG1960	acyl-CoA dehydrogenase activity
IB009_RS10530	COG4670	ketone body catabolic process
IB009_RS10545	COG2271	Major facilitator Superfamily
IB009_RS10550	COG0738	Major facilitator superfamily
IB009_RS10565	COG0628	permease
IB009_RS10570	COG0277	FAD linked oxidase domain protein
IB009_RS10570	COG0247	lactate metabolic process
IB009_RS10575	COG2050	protein possibly involved in aromatic compounds catabolism
IB009_RS10585	COG0316	Belongs to the HesB IscA family
IB009_RS10590	COG0719	Fe-S assembly protein
IB009_RS10595	COG0396	ATPase activity
IB009_RS10600	COG0719	Fe-S assembly protein
IB009_RS10615	COG1376	ErfK ybiS ycfS ynhG family protein
IB009_RS10620	COG4238	major outer membrane lipoprotein
IB009_RS10625	COG0469	pyruvate kinase activity
IB009_RS10635	COG0437	4 iron, 4 sulfur cluster binding
IB009_RS10640	COG2414	aldehyde ferredoxin oxidoreductase
IB009_RS10650	COG0437	4 iron, 4 sulfur cluster binding
IB009_RS10655	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
IB009_RS10665	COG4529	Protein conserved in bacteria
IB009_RS10685	COG3468	outer membrane autotransporter barrel domain protein
IB009_RS10695	COG0307	riboflavin synthase, alpha
IB009_RS10700	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IB009_RS10705	COG2814	Major facilitator Superfamily
IB009_RS10710	COG0583	DNA-binding transcription factor activity
IB009_RS10725	COG2814	Major facilitator Superfamily
IB009_RS10730	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IB009_RS10735	COG0791	NLP P60 protein
IB009_RS10740	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IB009_RS10745	COG1201	RNA secondary structure unwinding
IB009_RS10755	COG0346	lactoylglutathione lyase activity
IB009_RS10760	COG1902	pentaerythritol trinitrate reductase activity
IB009_RS10765	COG1309	transcriptional regulator
IB009_RS10770	COG3313	Fe-S protein
IB009_RS10775	COG4989	oxidoreductase activity
IB009_RS10780	COG2032	superoxide dismutase activity
IB009_RS10785	COG1289	transmembrane transporter activity
IB009_RS10790	COG1566	PFAM secretion protein HlyD family protein
IB009_RS10805	COG3133	Outer membrane lipoprotein
IB009_RS10815	COG3895	Periplasmic Protein
IB009_RS10830	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
IB009_RS10835	COG0625	glutathione transferase activity
IB009_RS10840	COG3104	oligopeptide transport
IB009_RS10845	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IB009_RS10855	COG4659	FMN binding
IB009_RS10895	COG0673	inositol 2-dehydrogenase activity
IB009_RS10905	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
IB009_RS10910	COG1263	PTS System
IB009_RS10910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IB009_RS10915	COG1609	Transcriptional regulator
IB009_RS10920	COG1028	Short-chain dehydrogenase reductase Sdr
IB009_RS10925	COG1309	transcriptional regulator
IB009_RS10930	COG3250	beta-galactosidase activity
IB009_RS10945	COG5339	Protein conserved in bacteria
IB009_RS10950	COG1482	cell wall glycoprotein biosynthetic process
IB009_RS10955	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IB009_RS10955	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IB009_RS10960	COG0114	fumarate hydratase activity
IB009_RS10970	COG2205	protein histidine kinase activity
IB009_RS10975	COG0745	RESPONSE REGULATOR receiver
IB009_RS10980	COG3136	membrane protein required for alginate biosynthesis
IB009_RS10990	COG0531	amino acid
IB009_RS11000	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
IB009_RS11005	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
IB009_RS11010	COG0628	permease
IB009_RS11025	COG3591	Belongs to the peptidase S1B family
IB009_RS11040	COG2814	Major facilitator Superfamily
IB009_RS11045	COG0583	DNA-binding transcription factor activity
IB009_RS11050	COG1940	carbohydrate kinase activity
IB009_RS11055	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IB009_RS11065	COG3381	protein complex oligomerization
IB009_RS11070	COG3302	dmso reductase anchor subunit
IB009_RS11075	COG0437	4 iron, 4 sulfur cluster binding
IB009_RS11085	COG0243	molybdopterin cofactor binding
IB009_RS11100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IB009_RS11115	COG4948	Mandelate Racemase Muconate Lactonizing
IB009_RS11120	COG1063	alcohol dehydrogenase
IB009_RS11130	COG0582	viral genome integration into host DNA
IB009_RS11140	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IB009_RS11165	COG1396	sequence-specific DNA binding
IB009_RS11180	COG1846	Transcriptional regulator
IB009_RS11210	COG1403	HNH endonuclease
IB009_RS11215	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
IB009_RS11220	COG0484	heat shock protein binding
IB009_RS11240	COG3064	Membrane
IB009_RS11260	COG3772	lysozyme
IB009_RS11300	COG0740	serine-type endopeptidase activity
IB009_RS11375	COG5301	cellulose 1,4-beta-cellobiosidase activity
IB009_RS11380	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
IB009_RS11395	COG0246	Mannitol dehydrogenase
IB009_RS11405	COG1802	Transcriptional regulator
IB009_RS11410	COG4221	oxidoreductase activity
IB009_RS11415	COG0339	signal peptide processing
IB009_RS11420	COG1546	Belongs to the CinA family
IB009_RS11425	COG3111	PFAM Bacterial OB fold (BOF) protein
IB009_RS11430	COG3706	GGDEF domain
IB009_RS11440	COG2814	Major facilitator Superfamily
IB009_RS11445	COG0697	spore germination
IB009_RS11450	COG2188	Transcriptional regulator
IB009_RS11460	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IB009_RS11465	COG1447	Phosphotransferase system cellobiose-specific component IIA
IB009_RS11475	COG2723	6-phospho-beta-galactosidase activity
IB009_RS11485	COG4977	sequence-specific DNA binding
IB009_RS11490	COG1846	Transcriptional regulator
IB009_RS11510	COG0583	DNA-binding transcription factor activity
IB009_RS11515	COG1012	belongs to the aldehyde dehydrogenase family
IB009_RS11520	COG2066	Belongs to the glutaminase family
IB009_RS11530	COG2199	diguanylate cyclase activity
IB009_RS11540	COG3781	membrane
IB009_RS11590	COG2911	Protein conserved in bacteria
IB009_RS11590	COG3210	domain, Protein
IB009_RS11595	COG1396	sequence-specific DNA binding
IB009_RS11600	COG3550	peptidyl-serine autophosphorylation
IB009_RS11615	COG0243	molybdopterin cofactor binding
IB009_RS11625	COG2207	Transcriptional regulator
IB009_RS11630	COG3119	arylsulfatase activity
IB009_RS11635	COG0641	radical SAM
IB009_RS11645	COG4178	(ABC) transporter
IB009_RS11650	COG4771	TonB-dependent receptor
IB009_RS11655	COG0612	Peptidase, M16
IB009_RS11660	COG0076	glutamate decarboxylase activity
IB009_RS11665	COG0531	amino acid
IB009_RS11670	COG1649	PFAM Uncharacterised BCR, COG1649
IB009_RS11685	COG2200	EAL domain
IB009_RS11685	COG2199	diguanylate cyclase activity
IB009_RS11685	COG2202	Pas domain
IB009_RS11690	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
IB009_RS11695	COG0747	negative chemotaxis
IB009_RS11700	COG0601	transmembrane transport
IB009_RS11705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IB009_RS11710	COG0444	Belongs to the ABC transporter superfamily
IB009_RS11715	COG4608	Belongs to the ABC transporter superfamily
IB009_RS11720	COG1764	response to oxidative stress
IB009_RS11740	COG1064	alcohol dehydrogenase
IB009_RS11745	COG3093	addiction module antidote protein HigA
IB009_RS11750	COG2864	formate dehydrogenase
IB009_RS11755	COG0437	4 iron, 4 sulfur cluster binding
IB009_RS11765	COG0697	spore germination
IB009_RS11770	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IB009_RS11775	COG4886	Leucine-rich repeat (LRR) protein
IB009_RS11780	COG2223	nitrite transmembrane transporter activity
IB009_RS11785	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IB009_RS11790	COG1140	nitrate reductase beta subunit
IB009_RS11795	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
IB009_RS11800	COG2181	nitrate reductase activity
IB009_RS11805	COG0384	phenazine biosynthesis protein PhzF
IB009_RS11810	COG2162	N-hydroxyarylamine O-acetyltransferase activity
IB009_RS11815	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IB009_RS11835	COG3209	COG3209 Rhs family protein
IB009_RS11840	COG4584	PFAM Integrase catalytic
IB009_RS11845	COG1484	DNA-dependent DNA replication
IB009_RS11875	COG3209	COG3209 Rhs family protein
IB009_RS11890	COG0625	glutathione transferase activity
IB009_RS11895	COG1113	amino acid transport
IB009_RS11900	COG3391	amine dehydrogenase activity
IB009_RS11905	COG4772	TonB-dependent receptor
IB009_RS11910	COG1802	Transcriptional regulator
IB009_RS11915	COG2130	NADP-dependent
IB009_RS11920	COG1247	-acetyltransferase
IB009_RS11925	COG3238	Protein conserved in bacteria
IB009_RS11955	COG1177	transmembrane transport
IB009_RS11960	COG1176	ABC-type spermidine putrescine transport system, permease component I
IB009_RS11965	COG3842	ATPase activity
IB009_RS11970	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IB009_RS11975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IB009_RS11980	COG1598	PFAM Uncharacterised protein family UPF0150
IB009_RS11995	COG0826	peptidase U32
IB009_RS12000	COG1396	sequence-specific DNA binding
IB009_RS12005	COG3135	benzoate transporter
IB009_RS12010	COG0675	Transposase, IS605 OrfB family
IB009_RS12025	COG0500	methyltransferase
IB009_RS12030	COG1275	C4-dicarboxylate transporter malic acid transport protein
IB009_RS12035	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IB009_RS12040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IB009_RS12045	COG2841	Protein conserved in bacteria
IB009_RS12055	COG5383	Protein conserved in bacteria
IB009_RS12060	COG0583	DNA-binding transcription factor activity
IB009_RS12065	COG0840	transmembrane signaling receptor activity
IB009_RS12080	COG3038	cytochrome b561
IB009_RS12085	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IB009_RS12090	COG1012	belongs to the aldehyde dehydrogenase family
IB009_RS12095	COG1434	Gram-negative-bacterium-type cell wall biogenesis
IB009_RS12100	COG1643	Atp-dependent helicase
IB009_RS12110	COG2453	phosphatase
IB009_RS12110	COG0671	phosphoesterase, PA-phosphatase related
IB009_RS12115	COG2267	carboxylic ester hydrolase activity
IB009_RS12120	COG4589	Belongs to the CDS family
IB009_RS12125	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IB009_RS12135	COG0667	Aldo Keto reductase
IB009_RS12140	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IB009_RS12145	COG3327	negative regulation of DNA-templated transcription, initiation
IB009_RS12150	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
IB009_RS12155	COG0183	Belongs to the thiolase family
IB009_RS12160	COG2050	protein possibly involved in aromatic compounds catabolism
IB009_RS12165	COG1250	3-hydroxyacyl-CoA dehydrogenase
IB009_RS12170	COG1024	Enoyl-CoA hydratase
IB009_RS12175	COG1024	Enoyl-CoA hydratase
IB009_RS12180	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IB009_RS12185	COG2151	metal-sulfur cluster biosynthetic enzyme
IB009_RS12190	COG3396	Phenylacetate-CoA oxygenase
IB009_RS12195	COG3460	Phenylacetate-CoA oxygenase
IB009_RS12200	COG3396	Phenylacetate-CoA oxygenase
IB009_RS12205	COG1012	belongs to the aldehyde dehydrogenase family
IB009_RS12205	COG2030	dehydratase
IB009_RS12210	COG3733	amine oxidase
IB009_RS12215	COG1012	belongs to the aldehyde dehydrogenase family
IB009_RS12220	COG2207	Transcriptional regulator
IB009_RS12225	COG3784	Protein of unknown function (DUF1318)
IB009_RS12235	COG2911	Protein conserved in bacteria
IB009_RS12240	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IB009_RS12245	COG3187	Heat shock protein
IB009_RS12250	COG3042	response to heat
IB009_RS12255	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IB009_RS12255	COG1013	pyruvate-flavodoxin oxidoreductase activity
IB009_RS12255	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
IB009_RS12255	COG0674	pyruvate-flavodoxin oxidoreductase activity
IB009_RS12260	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IB009_RS12265	COG0589	response to stress
IB009_RS12275	COG0513	Belongs to the DEAD box helicase family
IB009_RS12285	COG3706	GGDEF domain
IB009_RS12290	COG2840	Smr protein MutS2
IB009_RS12295	COG0583	DNA-binding transcription factor activity
IB009_RS12300	COG1473	amidohydrolase
IB009_RS12305	COG1473	amidohydrolase
IB009_RS12310	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
IB009_RS12315	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IB009_RS12320	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IB009_RS12325	COG0589	response to stress
IB009_RS12330	COG3182	Iron-regulated membrane protein
IB009_RS12335	COG0668	transmembrane transport
IB009_RS12340	COG4166	transmembrane transport
IB009_RS12345	COG0583	DNA-binding transcription factor activity
IB009_RS12350	COG1073	alpha beta
IB009_RS12355	COG1073	alpha beta
IB009_RS12360	COG0702	epimerase
IB009_RS12365	COG2866	Carboxypeptidase
IB009_RS12370	COG4948	Mandelate Racemase Muconate Lactonizing
IB009_RS12375	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IB009_RS12380	COG3283	Transcriptional regulator of aromatic amino acids metabolism
IB009_RS12390	COG3106	COG3106 Predicted ATPase
IB009_RS12405	COG0366	Alpha amylase catalytic
IB009_RS12410	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IB009_RS12420	COG1983	PspC domain protein
IB009_RS12430	COG1842	Phage shock protein A
IB009_RS12435	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
IB009_RS12440	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IB009_RS12445	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IB009_RS12450	COG1012	belongs to the aldehyde dehydrogenase family
IB009_RS12455	COG1917	Cupin 2, conserved barrel domain protein
IB009_RS12455	COG1396	sequence-specific DNA binding
IB009_RS12460	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IB009_RS12465	COG0174	glutamine synthetase
IB009_RS12475	COG0531	amino acid
IB009_RS12485	COG4166	transmembrane transport
IB009_RS12490	COG4168	peptide transport system, permease
IB009_RS12495	COG4171	peptide transport system, permease
IB009_RS12500	COG4172	Belongs to the ABC transporter superfamily
IB009_RS12505	COG4172	Belongs to the ABC transporter superfamily
IB009_RS12515	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IB009_RS12520	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IB009_RS12520	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IB009_RS12535	COG5001	Diguanylate cyclase
IB009_RS12545	COG1349	DNA-binding transcription factor activity
IB009_RS12555	COG0023	Translation Initiation Factor
IB009_RS12565	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
IB009_RS12570	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
IB009_RS12575	COG0671	phosphoesterase, PA-phosphatase related
IB009_RS12585	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IB009_RS12610	COG0583	DNA-binding transcription factor activity
IB009_RS12615	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IB009_RS12625	COG0616	signal peptide processing
IB009_RS12630	COG1028	Short-chain dehydrogenase reductase Sdr
IB009_RS12635	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
IB009_RS12640	COG1187	pseudouridine synthase activity
IB009_RS12645	COG0009	L-threonylcarbamoyladenylate synthase
IB009_RS12650	COG0613	PHP domain protein
IB009_RS12660	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IB009_RS12665	COG0512	Glutamine amidotransferase of anthranilate synthase
IB009_RS12665	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IB009_RS12670	COG0134	indole-3-glycerol-phosphate synthase activity
IB009_RS12670	COG0135	phosphoribosylanthranilate isomerase activity
IB009_RS12685	COG3729	General stress protein
IB009_RS12690	COG3685	Protein conserved in bacteria
IB009_RS12695	COG3685	Protein conserved in bacteria
IB009_RS12715	COG0500	methyltransferase
IB009_RS12720	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
IB009_RS12725	COG5301	cellulose 1,4-beta-cellobiosidase activity
IB009_RS12855	COG3772	lysozyme
IB009_RS12900	COG0484	heat shock protein binding
IB009_RS12905	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
IB009_RS12910	COG1403	HNH endonuclease
IB009_RS12950	COG1846	Transcriptional regulator
IB009_RS12965	COG1396	sequence-specific DNA binding
IB009_RS12990	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IB009_RS13000	COG0582	viral genome integration into host DNA
IB009_RS13005	COG3047	cAMP biosynthetic process
IB009_RS13025	COG1607	acyl-coa hydrolase
IB009_RS13040	COG1484	DNA-dependent DNA replication
IB009_RS13045	COG4584	PFAM Integrase catalytic
IB009_RS13105	COG2350	Protein conserved in bacteria
IB009_RS13110	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IB009_RS13130	COG4608	Belongs to the ABC transporter superfamily
IB009_RS13135	COG0444	Belongs to the ABC transporter superfamily
IB009_RS13140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IB009_RS13145	COG0601	transmembrane transport
IB009_RS13150	COG4166	transmembrane transport
IB009_RS13160	COG2095	MarC family integral membrane protein
IB009_RS13165	COG1012	belongs to the aldehyde dehydrogenase family
IB009_RS13165	COG1454	alcohol dehydrogenase
IB009_RS13175	COG1435	thymidine kinase activity
IB009_RS13185	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IB009_RS13190	COG0745	RESPONSE REGULATOR receiver
IB009_RS13195	COG1752	Esterase of the alpha-beta hydrolase superfamily
IB009_RS13205	COG0788	formyltetrahydrofolate deformylase activity
IB009_RS13225	COG2181	nitrate reductase activity
IB009_RS13230	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
IB009_RS13235	COG1140	nitrate reductase beta subunit
IB009_RS13240	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IB009_RS13245	COG2223	nitrite transmembrane transporter activity
IB009_RS13250	COG3850	Histidine kinase
IB009_RS13255	COG2197	response regulator
IB009_RS13260	COG4932	domain protein
IB009_RS13265	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
IB009_RS13270	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
IB009_RS13275	COG4572	Cation transport regulator
IB009_RS13280	COG0387	Pfam Sodium calcium exchanger
IB009_RS13305	COG2912	Transglutaminase-like superfamily
IB009_RS13310	COG3094	Invasion gene expression up-regulator, SirB
IB009_RS13315	COG2890	protein-(glutamine-N5) methyltransferase activity
IB009_RS13340	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IB009_RS13345	COG0659	secondary active sulfate transmembrane transporter activity
IB009_RS13360	COG0012	GTP binding
IB009_RS13365	COG3468	outer membrane autotransporter barrel domain protein
IB009_RS13370	COG3284	Transcriptional regulator
IB009_RS13375	COG2376	Dihydroxyacetone kinase
IB009_RS13380	COG1461	Dihydroxyacetone kinase
IB009_RS13385	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IB009_RS13385	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IB009_RS13385	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
IB009_RS13405	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
IB009_RS13415	COG1619	proteins homologs of microcin C7 resistance protein MccF
IB009_RS13425	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IB009_RS13435	COG2719	SpoVR family
IB009_RS13455	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IB009_RS13460	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IB009_RS13475	COG0179	Fumarylacetoacetate (FAA) hydrolase
IB009_RS13500	COG2894	cell division
IB009_RS13585	COG2200	EAL domain
IB009_RS13590	COG0789	Transcriptional regulator
IB009_RS13595	COG5562	phage envelope protein
IB009_RS13615	COG0538	isocitrate dehydrogenase activity
IB009_RS13620	COG1187	pseudouridine synthase activity
IB009_RS13640	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IB009_RS13650	COG2205	protein histidine kinase activity
IB009_RS13655	COG2850	peptidyl-arginine hydroxylation
IB009_RS13665	COG3842	ATPase activity
IB009_RS13675	COG1177	transmembrane transport
IB009_RS13680	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IB009_RS13690	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IB009_RS13695	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IB009_RS13705	COG4591	ABC-type transport system involved in lipoprotein release permease component
IB009_RS13715	COG4591	ABC-type transport system involved in lipoprotein release permease component
IB009_RS13720	COG4763	Acyl-transferase
IB009_RS13725	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IB009_RS13730	COG1388	LysM domain
IB009_RS13730	COG1376	ErfK ybiS ycfS ynhG family protein
IB009_RS13740	COG1309	transcriptional regulator
IB009_RS13745	COG3134	Outer membrane lipoprotein
IB009_RS13750	COG1252	NADH dehydrogenase
IB009_RS13770	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
IB009_RS13775	COG5633	Lipoprotein
IB009_RS13780	COG0537	adenosine 5'-monophosphoramidase activity
IB009_RS13785	COG4773	Receptor
IB009_RS13790	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IB009_RS13790	COG1263	PTS System
IB009_RS13795	COG0084	hydrolase, TatD family'
IB009_RS13800	COG0470	DNA polymerase III
IB009_RS13810	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IB009_RS13815	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IB009_RS13820	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IB009_RS13830	COG1028	Short-chain dehydrogenase reductase Sdr
IB009_RS13835	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IB009_RS13855	COG1399	metal-binding, possibly nucleic acid-binding protein
IB009_RS13860	COG0424	maF-like protein
IB009_RS13865	COG0564	pseudouridine synthase activity
IB009_RS13870	COG1530	ribonuclease E activity
IB009_RS13875	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IB009_RS13880	COG1256	bacterial-type flagellum assembly
IB009_RS13885	COG3951	Flagellar rod assembly protein muramidase FlgJ
IB009_RS13885	COG1705	Flagellar rod assembly protein muramidase FlgJ
IB009_RS13900	COG4786	Flagellar basal body rod
IB009_RS13905	COG4787	bacterial-type flagellum-dependent cell motility
IB009_RS13910	COG1749	Flagellar hook protein flgE
IB009_RS13915	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
IB009_RS13920	COG1558	bacterial-type flagellum-dependent cell motility
IB009_RS13925	COG1815	bacterial-type flagellum-dependent cell motility
IB009_RS13930	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
IB009_RS13935	COG2747	anti-sigma28 factor FlgM
IB009_RS13940	COG3418	PFAM FlgN family protein
IB009_RS13945	COG0728	peptidoglycan biosynthetic process
IB009_RS13950	COG0673	inositol 2-dehydrogenase activity
IB009_RS13960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IB009_RS13970	COG2999	glutathione oxidoreductase activity
IB009_RS14005	COG3038	cytochrome b561
IB009_RS14010	COG2353	YceI-like domain
IB009_RS14020	COG1560	Kdo2-lipid A biosynthetic process
IB009_RS14035	COG5645	(Lipo)protein
IB009_RS14040	COG2943	transferase activity, transferring hexosyl groups
IB009_RS14055	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IB009_RS14060	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
IB009_RS14085	COG2197	response regulator
IB009_RS14100	COG1462	curli production assembly transport component CsgG
IB009_RS14110	COG3381	protein complex oligomerization
IB009_RS14150	COG3706	GGDEF domain
IB009_RS14155	COG0457	Tetratricopeptide repeat
IB009_RS14160	COG0726	polysaccharide deacetylase
IB009_RS14160	COG1649	PFAM Uncharacterised BCR, COG1649
IB009_RS14165	COG1215	transferase activity, transferring glycosyl groups
IB009_RS14170	COG3658	cytochrome
IB009_RS14175	COG1702	phosphate starvation-inducible protein PhoH
IB009_RS14185	COG2822	iron ion transport
IB009_RS14195	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IB009_RS14205	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IB009_RS14205	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IB009_RS14205	COG0506	proline dehydrogenase activity
IB009_RS14210	COG1309	transcriptional regulator
IB009_RS14245	COG2233	PERMEase
IB009_RS14250	COG3729	General stress protein
IB009_RS14290	COG0243	molybdopterin cofactor binding
IB009_RS14295	COG3005	denitrification pathway
IB009_RS14300	COG0745	RESPONSE REGULATOR receiver
IB009_RS14305	COG1879	ABC-type sugar transport system periplasmic component
IB009_RS14310	COG0784	Response regulator, receiver
IB009_RS14310	COG2205	protein histidine kinase activity
IB009_RS14310	COG2198	Histidine kinase
IB009_RS14315	COG0348	domain, Protein
IB009_RS14335	COG1278	Cold shock
IB009_RS14340	COG1278	Cold shock
IB009_RS14365	COG1484	DNA-dependent DNA replication
IB009_RS14370	COG4584	PFAM Integrase catalytic
IB009_RS14380	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IB009_RS14405	COG0640	Transcriptional regulator
IB009_RS14465	COG1596	polysaccharide export
IB009_RS14470	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IB009_RS14475	COG3206	protein involved in exopolysaccharide biosynthesis
IB009_RS14475	COG0489	protein tyrosine kinase activity
IB009_RS14490	COG1294	oxidase, subunit
IB009_RS14495	COG1271	oxidase subunit
IB009_RS14500	COG1773	rubredoxin
IB009_RS14505	COG1999	signal sequence binding
IB009_RS14510	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IB009_RS14515	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
IB009_RS14520	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
IB009_RS14525	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
IB009_RS14535	COG0670	Belongs to the BI1 family
IB009_RS14540	COG2920	part of a sulfur-relay system
IB009_RS14545	COG1254	Belongs to the acylphosphatase family
IB009_RS14560	COG1832	CoA-binding protein
IB009_RS14575	COG0210	DNA helicase
IB009_RS14580	COG3304	Inner membrane component domain
IB009_RS14585	COG1289	transmembrane transporter activity
IB009_RS14590	COG3070	regulator of competence-specific genes
IB009_RS14610	COG1067	ATP-dependent peptidase activity
IB009_RS14620	COG3130	regulation of translation
IB009_RS14625	COG3009	Protein conserved in bacteria
IB009_RS14630	COG3008	intermembrane lipid transfer
IB009_RS14630	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IB009_RS14635	COG2995	paraquat-inducible protein a
IB009_RS14640	COG0488	(ABC) transporter
IB009_RS14650	COG0633	Ferredoxin
IB009_RS14650	COG3217	Mosc domain protein beta barrel domain protein
IB009_RS14665	COG3121	Chaperone
IB009_RS14670	COG3539	Fimbrial protein
IB009_RS14675	COG3539	Fimbrial protein
IB009_RS14680	COG3539	Fimbrial protein
IB009_RS14685	COG3188	usher protein
IB009_RS14690	COG3121	Chaperone
IB009_RS14695	COG3539	Fimbrial protein
IB009_RS14700	COG0431	NADPH-dependent FMN reductase
IB009_RS14705	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IB009_RS14715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IB009_RS14725	COG0308	aminopeptidase N
IB009_RS14745	COG1448	Aminotransferase
IB009_RS14750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IB009_RS14755	COG3108	Peptidase M15
IB009_RS14760	COG2989	Protein conserved in bacteria
IB009_RS14770	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
IB009_RS14780	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IB009_RS14785	COG1434	Gram-negative-bacterium-type cell wall biogenesis
IB009_RS14790	COG3173	Aminoglycoside phosphotransferase
IB009_RS14805	COG3214	Protein conserved in bacteria
IB009_RS14815	COG1132	(ABC) transporter
IB009_RS14820	COG2333	competence protein COMEC
IB009_RS14820	COG0658	competence protein
IB009_RS14830	COG0539	negative regulation of cytoplasmic translation
IB009_RS14840	COG0501	Belongs to the peptidase M48B family
IB009_RS14855	COG2323	membrane
IB009_RS14860	COG1944	ATP diphosphatase activity
IB009_RS14865	COG2116	formate transmembrane transporter activity
IB009_RS14870	COG1882	Formate acetyltransferase
IB009_RS14875	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IB009_RS14880	COG2249	NAD(P)H dehydrogenase (quinone) activity
IB009_RS14885	COG0583	DNA-binding transcription factor activity
IB009_RS14890	COG0531	amino acid
IB009_RS14900	COG1335	isochorismatase
IB009_RS14905	COG3302	dmso reductase anchor subunit
IB009_RS14910	COG0437	4 iron, 4 sulfur cluster binding
IB009_RS14915	COG0243	molybdopterin cofactor binding
IB009_RS14925	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IB009_RS14940	COG1522	sequence-specific DNA binding
IB009_RS14945	COG0492	ferredoxin-NADP+ reductase activity
IB009_RS14950	COG4988	ABC transporter
IB009_RS14955	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IB009_RS14975	COG0542	response to heat
IB009_RS14985	COG1278	Cold shock
IB009_RS14990	COG0577	efflux transmembrane transporter activity
IB009_RS14990	COG1136	(ABC) transporter
IB009_RS14995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IB009_RS15000	COG2990	Protein conserved in bacteria
IB009_RS15005	COG3593	DNA synthesis involved in DNA repair
IB009_RS15015	COG2431	L-lysine efflux transmembrane transporter activity
IB009_RS15030	COG0028	Belongs to the TPP enzyme family
IB009_RS15035	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
IB009_RS15040	COG0702	epimerase
IB009_RS15045	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IB009_RS15050	COG3023	N-Acetylmuramoyl-L-alanine amidase
IB009_RS15065	COG1126	abc transporter atp-binding protein
IB009_RS15070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IB009_RS15075	COG4215	(ABC) transporter
IB009_RS15080	COG4160	amino acid transport
IB009_RS15085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IB009_RS15100	COG1177	transmembrane transport
IB009_RS15105	COG1176	ABC-type spermidine putrescine transport system, permease component I
IB009_RS15110	COG3842	ATPase activity
IB009_RS15115	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IB009_RS15130	COG0778	Nitroreductase
IB009_RS15140	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IB009_RS15195	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IB009_RS15205	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
IB009_RS15300	COG4695	Portal protein
IB009_RS15350	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IB009_RS15390	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IB009_RS15395	COG3226	Transcriptional regulator
IB009_RS15400	COG0738	Major facilitator superfamily
IB009_RS15405	COG0561	phosphatase activity
IB009_RS15415	COG2814	Major facilitator Superfamily
IB009_RS15420	COG0671	phosphoesterase, PA-phosphatase related
IB009_RS15425	COG1349	DNA-binding transcription factor activity
IB009_RS15430	COG1686	Belongs to the peptidase S11 family
IB009_RS15435	COG0625	glutathione transferase activity
IB009_RS15440	COG2133	pyrroloquinoline quinone binding
IB009_RS15455	COG2199	diguanylate cyclase activity
IB009_RS15460	COG2200	EAL domain
IB009_RS15485	COG1446	asparaginase
IB009_RS15490	COG0303	'Molybdopterin
IB009_RS15495	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IB009_RS15500	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IB009_RS15505	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IB009_RS15510	COG1882	Formate acetyltransferase
IB009_RS15515	COG0561	phosphatase activity
IB009_RS15525	COG3547	Transposase (IS116 IS110 IS902 family)
IB009_RS15530	COG0488	(ABC) transporter
IB009_RS15535	COG1376	ErfK ybiS ycfS ynhG family protein
IB009_RS15540	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IB009_RS15545	COG1321	iron dependent repressor
IB009_RS15555	COG2194	sulfuric ester hydrolase activity
IB009_RS15560	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IB009_RS15570	COG5006	permease, DMT superfamily
IB009_RS15580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IB009_RS15585	COG0765	amino acid transport
IB009_RS15590	COG1126	abc transporter atp-binding protein
IB009_RS15595	COG0668	transmembrane transport
IB009_RS15610	COG4774	siderophore transport
IB009_RS15620	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IB009_RS15630	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
IB009_RS15635	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IB009_RS15640	COG1199	ATP-dependent helicase activity
IB009_RS15645	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
IB009_RS15650	COG0513	Belongs to the DEAD box helicase family
IB009_RS15655	COG1309	transcriptional regulator
IB009_RS15665	COG1131	(ABC) transporter
IB009_RS15670	COG0842	Transport permease protein
IB009_RS15675	COG0842	Transport permease protein
IB009_RS15685	COG3568	Endonuclease Exonuclease Phosphatase
IB009_RS15690	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IB009_RS15695	COG0392	lysyltransferase activity
IB009_RS15700	COG0670	Belongs to the BI1 family
IB009_RS15705	COG0670	Belongs to the BI1 family
IB009_RS15710	COG0314	molybdopterin synthase activity
IB009_RS15715	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IB009_RS15725	COG0521	Mo-molybdopterin cofactor biosynthetic process
IB009_RS15735	COG0391	Required for morphogenesis under gluconeogenic growth conditions
IB009_RS15745	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IB009_RS15750	COG2226	methyltransferase
IB009_RS15765	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IB009_RS15770	COG1881	PFAM PEBP family protein
IB009_RS15775	COG4677	pectinesterase activity
IB009_RS15780	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IB009_RS15785	COG0471	metal ion transport
IB009_RS15790	COG2828	Protein conserved in bacteria
IB009_RS15795	COG0583	DNA-binding transcription factor activity
IB009_RS15805	COG0561	phosphatase activity
IB009_RS15815	COG4149	molybdate abc transporter
IB009_RS15820	COG0725	ABC transporter, periplasmic molybdate-binding protein
IB009_RS15830	COG2005	Transcriptional regulator
IB009_RS15830	COG3585	molybdate ion transport
IB009_RS15835	COG1119	ATPase activity
IB009_RS15840	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IB009_RS15845	COG1085	galactose-1-phosphate uridylyltransferase
IB009_RS15855	COG2017	converts alpha-aldose to the beta-anomer
IB009_RS15865	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IB009_RS15875	COG1230	cation diffusion facilitator family transporter
IB009_RS15880	COG3201	nicotinamide mononucleotide transporter
IB009_RS15930	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
IB009_RS15935	COG2885	chlorophyll binding
IB009_RS15945	COG3064	Membrane
IB009_RS15950	COG0848	biopolymer transport protein
IB009_RS15955	COG0811	peptide transport
IB009_RS15960	COG0824	Thioesterase
IB009_RS15965	COG3790	cyd operon protein YbgE
IB009_RS15970	COG4890	Cyd operon protein YbgT
IB009_RS15975	COG1294	oxidase, subunit
IB009_RS15980	COG1271	oxidase subunit
IB009_RS15985	COG0383	alpha-mannosidase activity
IB009_RS15990	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IB009_RS15990	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IB009_RS15990	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IB009_RS15995	COG2188	Transcriptional regulator
IB009_RS16000	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IB009_RS16010	COG0508	dehydrogenase complex catalyzes the overall conversion of
IB009_RS16015	COG0567	Dehydrogenase, E1 component
IB009_RS16020	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IB009_RS16025	COG1053	succinate dehydrogenase
IB009_RS16030	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IB009_RS16035	COG2009	succinate dehydrogenase
IB009_RS16045	COG0372	Belongs to the citrate synthase family
IB009_RS16050	COG3539	Fimbrial protein
IB009_RS16055	COG3188	usher protein
IB009_RS16060	COG3121	Chaperone
IB009_RS16065	COG3539	Fimbrial protein
IB009_RS16070	COG3180	Ammonia monooxygenase
IB009_RS16085	COG1984	allophanate hydrolase subunit 2
IB009_RS16090	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
IB009_RS16095	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IB009_RS16105	COG0415	Belongs to the DNA photolyase family
IB009_RS16110	COG3272	Protein of unknown function (DUF1722)
IB009_RS16140	COG3209	COG3209 Rhs family protein
IB009_RS16170	COG2205	protein histidine kinase activity
IB009_RS16175	COG0745	RESPONSE REGULATOR receiver
IB009_RS16185	COG1982	Orn Lys Arg decarboxylase major
IB009_RS16190	COG0531	amino acid
IB009_RS16195	COG0033	Phosphoglucomutase
IB009_RS16200	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
IB009_RS16205	COG0596	Alpha beta hydrolase
IB009_RS16215	COG0716	FMN binding
IB009_RS16225	COG0735	belongs to the Fur family
IB009_RS16245	COG1263	PTS System
IB009_RS16245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IB009_RS16245	COG2190	(PTS) system
IB009_RS16255	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IB009_RS16260	COG1940	carbohydrate kinase activity
IB009_RS16260	COG1846	Transcriptional regulator
IB009_RS16265	COG0647	UMP catabolic process
IB009_RS16270	COG0367	asparagine synthase
IB009_RS16310	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IB009_RS16320	COG1702	phosphate starvation-inducible protein PhoH
IB009_RS16330	COG4535	Mg2 and Co2 transporter CorC
IB009_RS16335	COG0815	Transfers the fatty acyl group on membrane lipoproteins
IB009_RS16345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IB009_RS16350	COG0765	amino acid transport
IB009_RS16355	COG0765	amino acid transport
IB009_RS16360	COG1126	abc transporter atp-binding protein
IB009_RS16370	COG0443	Heat shock 70 kDa protein
IB009_RS16375	COG2214	Heat shock protein DnaJ domain protein
IB009_RS16385	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
IB009_RS16390	COG2214	Heat shock protein DnaJ domain protein
IB009_RS16400	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
IB009_RS16405	COG2888	peptidyl-tyrosine sulfation
IB009_RS16420	COG1466	dna polymerase III delta subunit
IB009_RS16430	COG0406	alpha-ribazole phosphatase activity
IB009_RS16435	COG0799	negative regulation of ribosome biogenesis
IB009_RS16445	COG0768	penicillin binding
IB009_RS16450	COG0772	Belongs to the SEDS family
IB009_RS16455	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IB009_RS16460	COG1686	Belongs to the peptidase S11 family
IB009_RS16475	COG0583	DNA-binding transcription factor activity
IB009_RS16485	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IB009_RS16490	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IB009_RS16510	COG3069	C4-dicarboxylate transmembrane transporter activity
IB009_RS16515	COG4565	transcriptional regulatory protein
IB009_RS16520	COG3290	protein histidine kinase activity
IB009_RS16525	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
IB009_RS16535	COG2301	Belongs to the HpcH HpaI aldolase family
IB009_RS16540	COG3051	citrate lyase alpha subunit
IB009_RS16555	COG0471	metal ion transport
IB009_RS16560	COG3719	Belongs to the RNase T2 family
IB009_RS16565	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IB009_RS16570	COG1063	alcohol dehydrogenase
IB009_RS16575	COG0589	response to stress
IB009_RS16580	COG3634	alkyl hydroperoxide reductase activity
IB009_RS16585	COG0450	alkyl hydroperoxide reductase
IB009_RS16590	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IB009_RS16595	COG0583	DNA-binding transcription factor activity
IB009_RS16600	COG3969	phosphoadenosine phosphosulfate
IB009_RS16605	COG1475	DNA binding
IB009_RS16610	COG0436	Aminotransferase
IB009_RS16615	COG0371	Dehydrogenase
IB009_RS16620	COG2879	small protein
IB009_RS16625	COG1966	Carbon starvation protein
IB009_RS16630	COG2050	protein possibly involved in aromatic compounds catabolism
IB009_RS16635	COG1028	Short-chain dehydrogenase reductase Sdr
IB009_RS16640	COG1535	isochorismatase
IB009_RS16640	COG3433	isochorismatase activity
IB009_RS16645	COG1021	2,3-dihydroxybenzoate-AMP ligase
IB009_RS16650	COG1169	isochorismate synthase
IB009_RS16655	COG4592	Periplasmic binding protein
IB009_RS16665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IB009_RS16670	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IB009_RS16675	COG1120	ATPase activity
IB009_RS16680	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
IB009_RS16685	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IB009_RS16685	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
IB009_RS16690	COG3251	PFAM MbtH domain protein
IB009_RS16695	COG2382	esterase
IB009_RS16700	COG4771	TonB-dependent receptor
IB009_RS16705	COG2977	Belongs to the P-Pant transferase superfamily
IB009_RS16730	COG2315	Protein conserved in bacteria
IB009_RS16735	COG0778	Nitroreductase
IB009_RS16740	COG0668	transmembrane transport
IB009_RS16745	COG1113	amino acid transport
IB009_RS16750	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IB009_RS16790	COG2207	Transcriptional regulator
IB009_RS16800	COG2197	response regulator
IB009_RS16805	COG3539	Fimbrial protein
IB009_RS16810	COG3539	Fimbrial protein
IB009_RS16820	COG3121	Chaperone
IB009_RS16840	COG2501	S4 domain
IB009_RS16845	COG1988	membrane-bound metal-dependent
IB009_RS16855	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IB009_RS16865	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IB009_RS16870	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IB009_RS16875	COG0549	Belongs to the carbamate kinase family
IB009_RS16885	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IB009_RS16890	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IB009_RS16895	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
IB009_RS16900	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IB009_RS16905	COG3257	ureidoglycine aminohydrolase activity
IB009_RS16910	COG1929	Belongs to the glycerate kinase type-1 family
IB009_RS16915	COG2233	PERMEase
IB009_RS16925	COG1953	Uracil, thiamine, allantoin
IB009_RS16930	COG2084	Dehydrogenase
IB009_RS16935	COG3622	Belongs to the hyi family
IB009_RS16940	COG3960	tartronate-semialdehyde synthase activity
IB009_RS16945	COG1414	Transcriptional regulator
IB009_RS16955	COG0583	DNA-binding transcription factor activity
IB009_RS16965	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
IB009_RS16970	COG4181	ATPase activity
IB009_RS16975	COG2755	lipolytic protein G-D-S-L family
IB009_RS16980	COG0300	oxidoreductase activity
IB009_RS16985	COG3118	belongs to the thioredoxin family
IB009_RS16990	COG0390	transport system, permease component
IB009_RS16995	COG4619	ABC transporter
IB009_RS17000	COG0330	HflC and HflK could
IB009_RS17005	COG1585	Membrane protein implicated in regulation of membrane protease activity
IB009_RS17010	COG0789	Transcriptional regulator
IB009_RS17015	COG0531	amino acid
IB009_RS17020	COG2066	Belongs to the glutaminase family
IB009_RS17025	COG2217	Heavy metal translocating P-type atpase
IB009_RS17030	COG3093	addiction module antidote protein HigA
IB009_RS17035	COG3735	TraB family
IB009_RS17040	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IB009_RS17045	COG0737	Belongs to the 5'-nucleotidase family
IB009_RS17050	COG2223	nitrite transmembrane transporter activity
IB009_RS17055	COG4651	solute:proton antiporter activity
IB009_RS17055	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IB009_RS17060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IB009_RS17095	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IB009_RS17105	COG2832	Protein of unknown function (DUF454)
IB009_RS17110	COG3923	Primosomal replication protein n
IB009_RS17120	COG1196	nuclear chromosome segregation
IB009_RS17120	COG3264	Mechanosensitive ion channel
IB009_RS17125	COG1309	transcriptional regulator
IB009_RS17130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IB009_RS17135	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IB009_RS17150	COG0110	maltose O-acetyltransferase activity
IB009_RS17160	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IB009_RS17165	COG5507	3-demethylubiquinone-9 3-methyltransferase
IB009_RS17175	COG3695	enzyme binding
IB009_RS17180	COG3126	Type III secretion system lipoprotein chaperone (YscW)
IB009_RS17185	COG1946	Acyl-CoA thioesterase
IB009_RS17190	COG0004	ammonium transporteR
IB009_RS17195	COG0347	Belongs to the P(II) protein family
IB009_RS17200	COG1132	(ABC) transporter
IB009_RS17205	COG1132	(ABC) transporter
IB009_RS17210	COG1522	sequence-specific DNA binding
IB009_RS17220	COG4533	DNA binding
IB009_RS17230	COG0824	Thioesterase
IB009_RS17235	COG1555	photosystem II stabilization
IB009_RS17240	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IB009_RS17245	COG0776	regulation of translation
IB009_RS17250	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IB009_RS17270	COG0271	Belongs to the BolA IbaG family
IB009_RS17275	COG3056	Lipoprotein
IB009_RS17280	COG2223	nitrite transmembrane transporter activity
IB009_RS17285	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IB009_RS17290	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IB009_RS17295	COG1845	cytochrome c oxidase, subunit III
IB009_RS17300	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IB009_RS17325	COG2814	Major facilitator Superfamily
IB009_RS17335	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IB009_RS17340	COG0693	protein deglycase activity
IB009_RS17355	COG0142	geranyltranstransferase activity
IB009_RS17365	COG0667	Aldo Keto reductase
IB009_RS17370	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IB009_RS17375	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IB009_RS17390	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IB009_RS17390	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IB009_RS17400	COG4238	major outer membrane lipoprotein
IB009_RS17405	COG3248	Nucleoside-binding outer membrane protein
IB009_RS17410	COG1403	HNH endonuclease
IB009_RS17415	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IB009_RS17420	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IB009_RS17425	COG1862	Preprotein translocase
IB009_RS17445	COG0366	Alpha amylase catalytic
IB009_RS17450	COG1113	amino acid transport
IB009_RS17455	COG1114	Component of the transport system for branched-chain amino acids
IB009_RS17460	COG5002	protein histidine kinase activity
IB009_RS17465	COG0745	RESPONSE REGULATOR receiver
IB009_RS17470	COG0420	3'-5' exonuclease activity
IB009_RS17475	COG0419	ATPase involved in DNA repair
IB009_RS17480	COG2814	Major facilitator Superfamily
IB009_RS17485	COG1940	carbohydrate kinase activity
IB009_RS17505	COG4126	flavin adenine dinucleotide binding
IB009_RS17525	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IB009_RS17530	COG3706	GGDEF domain
IB009_RS17540	COG1785	Belongs to the alkaline phosphatase family
IB009_RS17555	COG1181	Belongs to the D-alanine--D-alanine ligase family
IB009_RS17575	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
IB009_RS17580	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IB009_RS17585	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IB009_RS17605	COG0113	porphobilinogen synthase activity
IB009_RS17610	COG2175	clavaminate synthase activity
IB009_RS17615	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IB009_RS17625	COG4521	taurine ABC transporter
IB009_RS17635	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IB009_RS17640	COG1215	transferase activity, transferring glycosyl groups
IB009_RS17670	COG3122	Protein conserved in bacteria
IB009_RS17675	COG2814	Major facilitator Superfamily
IB009_RS17710	COG1414	Transcriptional regulator
IB009_RS17715	COG1609	Transcriptional regulator
IB009_RS17725	COG2223	nitrite transmembrane transporter activity
IB009_RS17730	COG0110	maltose O-acetyltransferase activity
IB009_RS17735	COG2807	transmembrane transport
IB009_RS17745	COG0288	reversible hydration of carbon dioxide
IB009_RS17750	COG0583	DNA-binding transcription factor activity
IB009_RS17755	COG0402	S-adenosylhomocysteine deaminase activity
IB009_RS17760	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IB009_RS17765	COG3547	Transposase (IS116 IS110 IS902 family)
IB009_RS17770	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IB009_RS17775	COG2079	MmgE PrpD family protein
IB009_RS17780	COG0372	Belongs to the citrate synthase family
IB009_RS17785	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IB009_RS17790	COG3829	transcription factor binding
IB009_RS17800	COG1280	lysine exporter protein (LysE YggA)
IB009_RS17815	COG1064	alcohol dehydrogenase
IB009_RS17825	COG1172	Belongs to the binding-protein-dependent transport system permease family
IB009_RS17830	COG1129	ABC transporter
IB009_RS17835	COG1879	ABC-type sugar transport system periplasmic component
IB009_RS17845	COG0402	S-adenosylhomocysteine deaminase activity
IB009_RS17850	COG0549	Belongs to the carbamate kinase family
IB009_RS17855	COG1304	FMN binding
IB009_RS17870	COG2771	luxR family
IB009_RS17870	COG2200	EAL domain
IB009_RS17885	COG4584	PFAM Integrase catalytic
IB009_RS17890	COG1484	DNA-dependent DNA replication
IB009_RS17900	COG3468	outer membrane autotransporter barrel domain protein
IB009_RS17910	COG1556	Lactate utilization protein
IB009_RS17915	COG1139	Iron-sulfur cluster binding protein
IB009_RS17920	COG0247	lactate metabolic process
IB009_RS17925	COG2207	Transcriptional regulator
IB009_RS17930	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IB009_RS17940	COG3059	membrane
IB009_RS17945	COG0656	L-ascorbic acid biosynthetic process
IB009_RS17950	COG3708	Transcriptional regulator
IB009_RS17950	COG2207	Transcriptional regulator
IB009_RS17955	COG1388	LysM domain
IB009_RS17995	COG3188	usher protein
IB009_RS18005	COG3121	Chaperone
IB009_RS18010	COG0727	PFAM Uncharacterised protein family (UPF0153)
IB009_RS18015	COG3477	response to acidic pH
IB009_RS18020	COG2080	2 iron, 2 sulfur cluster binding
IB009_RS18025	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
IB009_RS18030	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IB009_RS18035	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IB009_RS18060	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IB009_RS18080	COG2195	Cleaves the N-terminal amino acid of tripeptides
IB009_RS18085	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IB009_RS18090	COG1690	Belongs to the RtcB family
IB009_RS18095	COG0454	-acetyltransferase
IB009_RS18125	COG0791	NLP P60 protein
IB009_RS18130	COG3077	Addiction module antitoxin, RelB DinJ family
IB009_RS18135	COG3041	Addiction module toxin RelE StbE family
IB009_RS18140	COG3034	peptidoglycan biosynthetic process
IB009_RS18145	COG0121	glutamine amidotransferase
IB009_RS18155	COG1960	acyl-CoA dehydrogenase activity
IB009_RS18165	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IB009_RS18200	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IB009_RS18210	COG2226	methyltransferase
IB009_RS18220	COG0741	lytic transglycosylase activity
IB009_RS18220	COG1388	LysM domain
IB009_RS18225	COG2226	methyltransferase
IB009_RS18235	COG0583	DNA-binding transcription factor activity
IB009_RS18240	COG0656	L-ascorbic acid biosynthetic process
IB009_RS18275	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IB009_RS18280	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IB009_RS18285	COG2011	ABC-type metal ion transport system permease component
IB009_RS18290	COG1464	Belongs to the NlpA lipoprotein family
IB009_RS18300	COG1720	tRNA m6t6A37 methyltransferase activity
IB009_RS18315	COG3015	lipoprotein NlpE involved in copper resistance
IB009_RS18320	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IB009_RS18325	COG4681	YaeQ
IB009_RS18335	COG4568	rho-dependent transcription termination
IB009_RS18345	COG0346	lactoylglutathione lyase activity
IB009_RS18350	COG1982	Orn Lys Arg decarboxylase major
IB009_RS18360	COG0587	DNA-directed DNA polymerase activity
IB009_RS18385	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IB009_RS18390	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
IB009_RS18400	COG0750	zinc metalloprotease
IB009_RS18405	COG0575	Belongs to the CDS family
IB009_RS18410	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IB009_RS18415	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
IB009_RS18440	COG0024	Methionine aminopeptidase
IB009_RS18460	COG3835	regulator
IB009_RS18465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IB009_RS18480	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IB009_RS18485	COG2860	membrane
IB009_RS18510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IB009_RS18515	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IB009_RS18520	COG1120	ATPase activity
IB009_RS18525	COG4774	siderophore transport
IB009_RS18530	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IB009_RS18535	COG1643	Atp-dependent helicase
IB009_RS18540	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IB009_RS18550	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IB009_RS18560	COG0617	tRNA 3'-terminal CCA addition
IB009_RS18565	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IB009_RS18570	COG3539	Fimbrial protein
IB009_RS18575	COG3121	Chaperone
IB009_RS18580	COG3188	usher protein
IB009_RS18585	COG3539	Fimbrial protein
IB009_RS18590	COG3539	Fimbrial protein
IB009_RS18595	COG3539	Fimbrial protein
IB009_RS18600	COG3539	Fimbrial protein
IB009_RS18615	COG5464	transposase or invertase
IB009_RS18625	COG0726	polysaccharide deacetylase
IB009_RS18630	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
IB009_RS18635	COG0842	Transport permease protein
IB009_RS18640	COG1131	(ABC) transporter
IB009_RS18645	COG0288	reversible hydration of carbon dioxide
IB009_RS18650	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
IB009_RS18655	COG4993	Dehydrogenase
IB009_RS18660	COG2132	Multicopper oxidase
IB009_RS18685	COG1049	propionate catabolic process, 2-methylcitrate cycle
IB009_RS18690	COG3064	Membrane
IB009_RS18695	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IB009_RS18700	COG0508	dehydrogenase complex catalyzes the overall conversion of
IB009_RS18705	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
IB009_RS18710	COG2186	Transcriptional regulator
IB009_RS18715	COG1113	amino acid transport
IB009_RS18720	COG3725	Membrane protein required for beta-lactamase induction
IB009_RS18725	COG3023	N-Acetylmuramoyl-L-alanine amidase
IB009_RS18730	COG0157	Belongs to the NadC ModD family
IB009_RS18735	COG4969	Belongs to the N-Me-Phe pilin family
IB009_RS18740	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IB009_RS18745	COG1459	type II secretion system
IB009_RS18760	COG0237	dephospho-CoA kinase activity
IB009_RS18775	COG3547	Transposase (IS116 IS110 IS902 family)
IB009_RS18780	COG0494	nUDIX hydrolase
IB009_RS18800	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IB009_RS18805	COG0849	cell division
IB009_RS18810	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IB009_RS18815	COG1181	Belongs to the D-alanine--D-alanine ligase family
IB009_RS18830	COG0772	Belongs to the SEDS family
IB009_RS18845	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IB009_RS18850	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IB009_RS18855	COG0768	penicillin binding
IB009_RS18860	COG3116	cell division
IB009_RS18875	COG1609	Transcriptional regulator
IB009_RS18885	COG0440	acetolactate synthase activity
IB009_RS18890	COG0028	Belongs to the TPP enzyme family
IB009_RS18900	COG0583	DNA-binding transcription factor activity
IB009_RS18915	COG0473	3-isopropylmalate dehydrogenase activity
IB009_RS18930	COG2814	Major facilitator Superfamily
IB009_RS18945	COG4143	(ABC) transporter
IB009_RS18950	COG1178	ABC-type Fe3 transport system permease component
IB009_RS18960	COG0586	Pfam SNARE associated Golgi protein
IB009_RS18965	COG4977	sequence-specific DNA binding
IB009_RS18980	COG0235	Class ii aldolase
IB009_RS18985	COG0417	DNA replication proofreading
IB009_RS18995	COG0564	pseudouridine synthase activity
IB009_RS19000	COG3547	Transposase (IS116 IS110 IS902 family)
IB009_RS19005	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IB009_RS19010	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
IB009_RS19015	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IB009_RS19040	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IB009_RS19055	COG2271	Major facilitator Superfamily
IB009_RS19065	COG0644	oxidoreductase
IB009_RS19115	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IB009_RS19120	COG0505	Belongs to the CarA family
IB009_RS19140	COG1047	Peptidyl-prolyl cis-trans
IB009_RS19155	COG0196	riboflavin kinase activity
IB009_RS19185	COG0583	DNA-binding transcription factor activity
IB009_RS19215	COG4735	regulation of single-species biofilm formation
IB009_RS19220	COG1584	GPR1 FUN34 yaaH family protein
IB009_RS19225	COG0521	Mo-molybdopterin cofactor biosynthetic process
IB009_RS19230	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IB009_RS19235	COG1115	amino acid carrier protein
IB009_RS19245	COG3547	Transposase (IS116 IS110 IS902 family)
IB009_RS19255	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IB009_RS19265	COG0527	aspartate kinase activity
IB009_RS19265	COG0460	homoserine dehydrogenase
IB009_RS19275	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
IB009_RS19285	COG0745	RESPONSE REGULATOR receiver
IB009_RS19290	COG4452	Inner membrane protein CreD
IB009_RS19295	COG2205	protein histidine kinase activity
IB009_RS19300	COG0745	RESPONSE REGULATOR receiver
IB009_RS19305	COG3045	CreA protein
IB009_RS19310	COG3708	Transcriptional regulator
IB009_RS19310	COG2207	Transcriptional regulator
IB009_RS19325	COG3547	Transposase (IS116 IS110 IS902 family)
IB009_RS19335	COG0741	lytic transglycosylase activity
IB009_RS19340	COG0488	(ABC) transporter
IB009_RS19345	COG1056	cytidyltransferase-related domain
IB009_RS19345	COG3172	ATPase kinase involved in NAD metabolism
IB009_RS19350	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IB009_RS19355	COG0560	Phosphoserine phosphatase
IB009_RS19360	COG3726	membrane protein affecting hemolysin expression
IB009_RS19395	COG1328	CTP reductase activity
IB009_RS19400	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IB009_RS19405	COG0084	hydrolase, TatD family'
IB009_RS19410	COG4667	esterase of the alpha-beta hydrolase superfamily
IB009_RS19420	COG2823	Periplasmic or secreted lipoprotein
IB009_RS19430	COG1011	Hydrolase
IB009_RS19435	COG0456	acetyltransferase
IB009_RS19440	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
IB009_RS19470	COG4114	ferric iron reductase
IB009_RS19475	COG2197	response regulator
IB009_RS19480	COG2197	response regulator
IB009_RS19485	COG2966	Psort location CytoplasmicMembrane, score
IB009_RS19500	COG1484	DNA-dependent DNA replication
IB009_RS19515	COG1063	alcohol dehydrogenase
IB009_RS19520	COG1802	Transcriptional regulator
IB009_RS19525	COG2271	Major facilitator Superfamily
IB009_RS19530	COG0840	transmembrane signaling receptor activity
IB009_RS19535	COG1966	Carbon starvation protein
IB009_RS19540	COG2879	small protein
IB009_RS19545	COG0523	cobalamin synthesis protein
IB009_RS19565	COG0732	type I restriction modification DNA specificity domain
IB009_RS19580	COG5457	Domain of unknown function (DUF1127)
IB009_RS19585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IB009_RS19595	COG2814	Major facilitator Superfamily
IB009_RS19600	COG2733	membrane
IB009_RS19605	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
IB009_RS19610	COG1924	4 iron, 4 sulfur cluster binding
IB009_RS19625	COG0477	Major facilitator Superfamily
IB009_RS19635	COG3366	ferrous iron transmembrane transporter activity
IB009_RS19640	COG0700	Nucleoside recognition
IB009_RS19645	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IB009_RS19650	COG0583	DNA-binding transcription factor activity
IB009_RS19670	COG2186	Transcriptional regulator
IB009_RS19675	COG0246	Mannitol dehydrogenase
IB009_RS19685	COG2610	gluconate transmembrane transporter activity
IB009_RS19710	COG1484	DNA-dependent DNA replication
IB009_RS19715	COG4584	PFAM Integrase catalytic
IB009_RS19740	COG2003	Belongs to the UPF0758 family
IB009_RS19765	COG2020	methyltransferase activity
IB009_RS19770	COG3468	outer membrane autotransporter barrel domain protein
IB009_RS19825	COG3436	PFAM IS66 Orf2 family protein
IB009_RS19830	COG4372	Transposase
IB009_RS19855	COG1595	DNA-templated transcription, initiation
IB009_RS19860	COG3712	iron ion homeostasis
IB009_RS19865	COG4772	TonB-dependent receptor
IB009_RS19870	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
IB009_RS19875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IB009_RS19880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IB009_RS19885	COG1120	ATPase activity
IB009_RS19890	COG2085	NADP oxidoreductase coenzyme F420-dependent
IB009_RS19900	COG0726	polysaccharide deacetylase
IB009_RS19905	COG0297	glycogen (starch) synthase activity
IB009_RS19910	COG2990	Protein conserved in bacteria
IB009_RS19925	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IB009_RS19940	COG1309	transcriptional regulator
IB009_RS19965	COG1064	alcohol dehydrogenase
IB009_RS19970	COG0433	COG0433 Predicted ATPase
IB009_RS19975	COG0795	lipopolysaccharide-transporting ATPase activity
IB009_RS19980	COG0795	lipopolysaccharide-transporting ATPase activity
IB009_RS19990	COG2927	DNA polymerase III (CHI subunit)
IB009_RS20000	COG4269	membrane
IB009_RS20005	COG0456	acetyltransferase
IB009_RS20010	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
IB009_RS20025	COG2731	YhcH YjgK YiaL family protein
IB009_RS20030	COG1309	transcriptional regulator
IB009_RS20035	COG1028	Short-chain dehydrogenase reductase Sdr
IB009_RS20040	COG0251	oxidation-reduction process
IB009_RS20060	COG0251	oxidation-reduction process
IB009_RS20065	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IB009_RS20075	COG1609	Transcriptional regulator
IB009_RS20080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IB009_RS20080	COG1263	PTS System
IB009_RS20085	COG0366	Alpha amylase catalytic
IB009_RS20090	COG1328	CTP reductase activity
IB009_RS20095	COG0602	queuosine metabolic process
IB009_RS20100	COG3783	Cytochrome b(562)
IB009_RS20105	COG0312	modulator of DNA gyrase
IB009_RS20115	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IB009_RS20125	COG1172	Belongs to the binding-protein-dependent transport system permease family
IB009_RS20130	COG1172	Belongs to the binding-protein-dependent transport system permease family
IB009_RS20135	COG1129	ABC transporter
IB009_RS20140	COG1879	ABC-type sugar transport system periplasmic component
IB009_RS20145	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IB009_RS20150	COG2105	PFAM AIG2 family protein
IB009_RS20155	COG2911	Protein conserved in bacteria
IB009_RS20160	COG0729	surface antigen
IB009_RS20170	COG1253	flavin adenine dinucleotide binding
IB009_RS20180	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
IB009_RS20185	COG1218	3'(2'),5'-bisphosphate nucleotidase
IB009_RS20190	COG0737	Belongs to the 5'-nucleotidase family
IB009_RS20195	COG1733	regulation of RNA biosynthetic process
IB009_RS20200	COG0702	epimerase
IB009_RS20205	COG0697	spore germination
IB009_RS20215	COG1113	amino acid transport
IB009_RS20220	COG0545	Peptidyl-prolyl cis-trans isomerase
IB009_RS20225	COG3061	Opacity-associated protein A
IB009_RS20245	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IB009_RS20285	COG3414	Phosphotransferase system galactitol-specific IIB component
IB009_RS20290	COG3037	sugar-specific permease SgaT UlaA
IB009_RS20305	COG1073	alpha beta
IB009_RS20310	COG3650	response to hydrogen peroxide
IB009_RS20320	COG1960	acyl-CoA dehydrogenase activity
IB009_RS20325	COG0754	glutathionylspermidine amidase activity
IB009_RS20335	COG3766	membrane
IB009_RS20355	COG2721	sulfolactate sulfo-lyase activity
IB009_RS20360	COG2271	Major facilitator Superfamily
IB009_RS20365	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IB009_RS20370	COG1414	Transcriptional regulator
IB009_RS20375	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IB009_RS20380	COG0557	exoribonuclease II activity
IB009_RS20395	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
IB009_RS20400	COG0330	HflC and HflK could
IB009_RS20405	COG0330	HflC and HflK could
IB009_RS20410	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IB009_RS20430	COG0860	N-Acetylmuramoyl-L-alanine amidase
IB009_RS20435	COG0802	atpase or kinase
IB009_RS20440	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IB009_RS20440	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IB009_RS20445	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IB009_RS20485	COG1511	domain protein
IB009_RS20485	COG3264	Mechanosensitive ion channel
IB009_RS20490	COG0531	amino acid
IB009_RS20500	COG1053	succinate dehydrogenase
IB009_RS20505	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IB009_RS20520	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IB009_RS20525	COG3040	lipid binding
IB009_RS20530	COG2076	Multidrug Resistance protein
IB009_RS20535	COG5510	response to toxic substance
IB009_RS20540	COG5510	response to toxic substance
IB009_RS20550	COG1509	lysine 2,3-aminomutase activity
IB009_RS20575	COG0531	amino acid
IB009_RS20580	COG3030	protein affecting phage T7 exclusion by the F plasmid
IB009_RS20585	COG1027	Aspartate ammonia-lyase
IB009_RS20590	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
IB009_RS20605	COG1309	transcriptional regulator
IB009_RS20615	COG3710	Transcriptional regulator
IB009_RS20620	COG0531	amino acid
IB009_RS20625	COG1982	Orn Lys Arg decarboxylase major
IB009_RS20630	COG3104	oligopeptide transport
IB009_RS20640	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IB009_RS20655	COG2388	GCN5-related N-acetyl-transferase
IB009_RS20660	COG3592	Divergent 4Fe-4S mono-cluster
IB009_RS20665	COG3290	protein histidine kinase activity
IB009_RS20670	COG4565	transcriptional regulatory protein
IB009_RS20675	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
IB009_RS20680	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IB009_RS20680	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IB009_RS20685	COG3647	Membrane
IB009_RS20690	COG2211	Major facilitator Superfamily
IB009_RS20695	COG1486	melibiose metabolic process
IB009_RS20700	COG2169	Transcriptional regulator
IB009_RS20705	COG1982	Orn Lys Arg decarboxylase major
IB009_RS20710	COG2207	Transcriptional regulator
IB009_RS20715	COG0531	amino acid
IB009_RS20720	COG2194	sulfuric ester hydrolase activity
IB009_RS20725	COG0745	RESPONSE REGULATOR receiver
IB009_RS20730	COG0642	Histidine kinase
IB009_RS20740	COG0477	Major facilitator Superfamily
IB009_RS20755	COG2824	Alkylphosphonate utilization operon protein PhnA
IB009_RS20760	COG2764	glyoxalase bleomycin resistance protein dioxygenase
IB009_RS20770	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
IB009_RS20775	COG3639	organic phosphonate transmembrane transporter activity
IB009_RS20780	COG2188	Transcriptional regulator
IB009_RS20785	COG3624	Phosphonate C-P lyase system protein PhnG
IB009_RS20790	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
IB009_RS20795	COG3626	phosphonate metabolism
IB009_RS20800	COG3627	carbon phosphorus lyase activity
IB009_RS20805	COG4107	phosphonate C-P lyase system protein PhnK
IB009_RS20810	COG4778	phosphonate C-P lyase system protein PhnL
IB009_RS20815	COG3454	Phosphonate metabolism
IB009_RS20820	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
IB009_RS20825	COG0456	acetyltransferase
IB009_RS20830	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
IB009_RS20840	COG0698	ribose 5-phosphate isomerase
IB009_RS20845	COG2015	COG2015, Alkyl sulfatase and related hydrolases
IB009_RS20855	COG1566	PFAM secretion protein HlyD family protein
IB009_RS20860	COG1289	transmembrane transporter activity
IB009_RS20875	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
IB009_RS20880	COG1301	dicarboxylic acid transport
IB009_RS20885	COG4235	cytochrome complex assembly
IB009_RS20890	COG3088	subunit of a heme lyase
IB009_RS20895	COG1138	Cytochrome C-type biogenesis protein
IB009_RS20900	COG3301	Polysulphide reductase, NrfD
IB009_RS20905	COG0437	4 iron, 4 sulfur cluster binding
IB009_RS20910	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
IB009_RS20920	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IB009_RS20925	COG3162	membrane
IB009_RS20940	COG0025	NhaP-type Na H and K H
IB009_RS20945	COG2252	PERMEase
IB009_RS20950	COG0789	Transcriptional regulator
IB009_RS20955	COG2207	Transcriptional regulator
IB009_RS20960	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IB009_RS21000	COG0629	single-stranded DNA binding
IB009_RS21005	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IB009_RS21010	COG2315	Protein conserved in bacteria
IB009_RS21015	COG0432	Pfam Uncharacterised protein family UPF0047
IB009_RS21020	COG3700	Belongs to the class B bacterial acid phosphatase family
IB009_RS21030	COG1448	Aminotransferase
IB009_RS21035	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IB009_RS21040	COG0305	Participates in initiation and elongation during chromosome replication
IB009_RS21045	COG0604	alcohol dehydrogenase
IB009_RS21055	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IB009_RS21070	COG0735	belongs to the Fur family
IB009_RS21075	COG3237	CsbD-like
IB009_RS21080	COG0534	Mate efflux family protein
IB009_RS21090	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IB009_RS21125	COG3842	ATPase activity
IB009_RS21130	COG2182	Extracellular solute-binding protein
IB009_RS21135	COG1175	transmembrane transport
IB009_RS21140	COG3833	ABC-type maltose transport systems, permease component
IB009_RS21145	COG2814	Major facilitator Superfamily
IB009_RS21145	COG0477	Major facilitator Superfamily
IB009_RS21160	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IB009_RS21185	COG0527	aspartate kinase activity
IB009_RS21190	COG0542	response to heat
IB009_RS21195	COG3541	Predicted nucleotidyltransferase
IB009_RS21210	COG1187	pseudouridine synthase activity
IB009_RS21220	COG1283	sodium-dependent phosphate transmembrane transporter activity
IB009_RS21225	COG0646	methionine synthase
IB009_RS21225	COG1410	methionine synthase
IB009_RS21230	COG1414	Transcriptional regulator
IB009_RS21245	COG2224	Isocitrate lyase
IB009_RS21250	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IB009_RS21260	COG0456	acetyltransferase
IB009_RS21290	COG0151	Belongs to the GarS family
IB009_RS21295	COG2204	response regulator
IB009_RS21300	COG4191	Histidine kinase
IB009_RS21305	COG3678	ATP-independent chaperone mediated protein folding
IB009_RS21320	COG3068	Protein conserved in bacteria
IB009_RS21355	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IB009_RS21360	COG2104	thiamine diphosphate biosynthetic process
IB009_RS21370	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IB009_RS21405	COG0250	Participates in transcription elongation, termination and antitermination
IB009_RS21410	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IB009_RS21445	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
IB009_RS21445	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
IB009_RS21495	COG1309	transcriptional regulator
IB009_RS21505	COG0583	DNA-binding transcription factor activity
IB009_RS21520	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IB009_RS21535	COG2194	sulfuric ester hydrolase activity
IB009_RS21540	COG2207	Transcriptional regulator
IB009_RS21545	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IB009_RS21550	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IB009_RS21555	COG1882	Formate acetyltransferase
IB009_RS21560	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IB009_RS21565	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IB009_RS21570	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IB009_RS21570	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IB009_RS21570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IB009_RS21575	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IB009_RS21580	COG0371	Dehydrogenase
IB009_RS21585	COG3738	Protein conserved in bacteria
IB009_RS21590	COG0697	spore germination
IB009_RS21600	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IB009_RS21605	COG0460	homoserine dehydrogenase
IB009_RS21605	COG0527	aspartate kinase activity
IB009_RS21610	COG0626	cystathionine gamma-synthase activity
IB009_RS21645	COG3209	COG3209 Rhs family protein
IB009_RS21655	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IB009_RS21660	COG1609	Transcriptional regulator
IB009_RS21665	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IB009_RS21680	COG1575	Belongs to the MenA family. Type 1 subfamily
IB009_RS21695	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IB009_RS21705	COG1494	fructose-1,6-bisphosphatase
IB009_RS21715	COG0589	response to stress
IB009_RS21720	COG3691	Protein conserved in bacteria
IB009_RS21725	COG3152	Membrane
IB009_RS21745	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IB009_RS21760	COG3678	ATP-independent chaperone mediated protein folding
IB009_RS21765	COG0745	RESPONSE REGULATOR receiver
IB009_RS21770	COG2205	protein histidine kinase activity
IB009_RS21775	COG2258	MOSC domain
IB009_RS21785	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IB009_RS21825	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IB009_RS21830	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IB009_RS21830	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IB009_RS21835	COG1363	Peptidase, m42
IB009_RS21840	COG3711	transcriptional antiterminator
IB009_RS21840	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IB009_RS21860	COG0437	4 iron, 4 sulfur cluster binding
IB009_RS21865	COG2864	formate dehydrogenase
IB009_RS21875	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IB009_RS21880	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IB009_RS21890	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
IB009_RS21900	COG0456	acetyltransferase
IB009_RS21915	COG1011	Hydrolase
IB009_RS21925	COG0477	Major facilitator Superfamily
IB009_RS21935	COG1063	alcohol dehydrogenase
IB009_RS21940	COG3684	Belongs to the aldolase LacD family
IB009_RS21945	COG2084	Dehydrogenase
IB009_RS21950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IB009_RS21955	COG1349	DNA-binding transcription factor activity
IB009_RS21960	COG2271	Major facilitator Superfamily
IB009_RS21965	COG1082	Xylose isomerase domain protein TIM barrel
IB009_RS21970	COG2188	Transcriptional regulator
IB009_RS21975	COG1217	gtp-binding protein TYPA
IB009_RS21980	COG0174	glutamine synthetase
IB009_RS21985	COG3852	Histidine kinase
IB009_RS21990	COG2204	response regulator
IB009_RS22000	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IB009_RS22015	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IB009_RS22015	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IB009_RS22020	COG0204	Acyl-transferase
IB009_RS22025	COG5339	Protein conserved in bacteria
IB009_RS22030	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IB009_RS22035	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IB009_RS22040	COG3084	Protein conserved in bacteria
IB009_RS22045	COG0746	molybdenum cofactor guanylyltransferase activity
IB009_RS22050	COG1763	Mo-molybdopterin cofactor biosynthetic process
IB009_RS22080	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
IB009_RS22085	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IB009_RS22090	COG1739	Uncharacterized protein family UPF0029
IB009_RS22110	COG0543	2 iron, 2 sulfur cluster binding
IB009_RS22115	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IB009_RS22120	COG0250	Participates in transcription elongation, termination and antitermination
IB009_RS22130	COG0805	protein transport
IB009_RS22135	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IB009_RS22140	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IB009_RS22150	COG3165	ubiquinone biosynthetic process from chorismate
IB009_RS22160	COG1322	Protein conserved in bacteria
IB009_RS22165	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
IB009_RS22170	COG0412	Dienelactone hydrolase
IB009_RS22180	COG0583	DNA-binding transcription factor activity
IB009_RS22185	COG0697	spore germination
IB009_RS22190	COG0561	phosphatase activity
IB009_RS22195	COG2267	carboxylic ester hydrolase activity
IB009_RS22200	COG1280	lysine exporter protein (LysE YggA)
IB009_RS22205	COG1280	lysine exporter protein (LysE YggA)
IB009_RS22210	COG0514	ATP-dependent DNA helicase (RecQ)
IB009_RS22215	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
IB009_RS22220	COG2050	protein possibly involved in aromatic compounds catabolism
IB009_RS22225	COG2962	Rard protein
IB009_RS22240	COG0598	Magnesium transport protein CorA
IB009_RS22245	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
IB009_RS22250	COG0210	DNA helicase
IB009_RS22255	COG1011	Hydrolase
IB009_RS22265	COG3159	Protein conserved in bacteria
IB009_RS22275	COG5567	small periplasmic lipoprotein
IB009_RS22285	COG3072	Adenylate cyclase
IB009_RS22295	COG1587	Uroporphyrinogen-III synthase
IB009_RS22300	COG2959	enzyme of heme biosynthesis
IB009_RS22305	COG3071	HemY protein
IB009_RS22310	COG3119	arylsulfatase activity
IB009_RS22315	COG0641	radical SAM
IB009_RS22340	COG1113	amino acid transport
IB009_RS22360	COG2244	polysaccharide biosynthetic process
IB009_RS22365	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IB009_RS22370	COG0456	acetyltransferase
IB009_RS22375	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IB009_RS22380	COG1088	dTDP-glucose 4,6-dehydratase activity
IB009_RS22385	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IB009_RS22390	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IB009_RS22395	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
IB009_RS22400	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IB009_RS22405	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IB009_RS22415	COG3118	belongs to the thioredoxin family
IB009_RS22430	COG0210	DNA helicase
IB009_RS22435	COG3692	DNA binding
IB009_RS22440	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IB009_RS22450	COG0583	DNA-binding transcription factor activity
IB009_RS22455	COG3547	Transposase (IS116 IS110 IS902 family)
IB009_RS22460	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IB009_RS22470	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IB009_RS22475	COG3978	acetolactate synthase activity
IB009_RS22495	COG0606	chelatase, subunit chli
IB009_RS22500	COG3085	chromosome segregation
IB009_RS22540	COG2186	Transcriptional regulator
IB009_RS22545	COG0477	Major facilitator Superfamily
IB009_RS22550	COG1609	Transcriptional regulator
IB009_RS22555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IB009_RS22560	COG1879	ABC-type sugar transport system periplasmic component
IB009_RS22565	COG1172	Belongs to the binding-protein-dependent transport system permease family
IB009_RS22570	COG1129	ABC transporter
IB009_RS22600	COG1522	sequence-specific DNA binding
IB009_RS22605	COG0716	FMN binding
IB009_RS22620	COG3312	ion transport
IB009_RS22670	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IB009_RS22755	COG3188	usher protein
IB009_RS22765	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IB009_RS22770	COG0573	inorganic phosphate transmembrane transporter activity
IB009_RS22775	COG0581	inorganic phosphate transmembrane transporter activity
IB009_RS22780	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IB009_RS22785	COG0704	Plays a role in the regulation of phosphate uptake
IB009_RS22790	COG3711	transcriptional antiterminator
IB009_RS22795	COG1263	PTS System
IB009_RS22795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IB009_RS22795	COG2190	(PTS) system
IB009_RS22800	COG2723	6-phospho-beta-galactosidase activity
IB009_RS22810	COG2382	esterase
IB009_RS22815	COG0363	glucosamine-6-phosphate deaminase activity
IB009_RS22820	COG3196	Protein conserved in bacteria
IB009_RS22830	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IB009_RS22835	COG2252	PERMEase
IB009_RS22840	COG0431	NADPH-dependent FMN reductase
IB009_RS22845	COG2091	lysine biosynthetic process via aminoadipic acid
IB009_RS22860	COG0814	amino acid
IB009_RS22920	COG3609	addiction module antidote protein, CC2985 family
IB009_RS22955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IB009_RS22960	COG1271	oxidase subunit
IB009_RS22965	COG1294	oxidase, subunit
IB009_RS23050	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IB009_RS23280	COG4584	PFAM Integrase catalytic
IB009_RS23285	COG1484	DNA-dependent DNA replication
IB009_RS23365	COG4372	Transposase
IB009_RS23370	COG3436	PFAM IS66 Orf2 family protein
IB009_RS23405	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
IB009_RS23410	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IB009_RS23585	COG0756	dUTP diphosphatase activity
IB009_RS23610	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IB009_RS23665	COG1403	HNH endonuclease
IB009_RS23690	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IB009_RS23755	COG0717	Belongs to the dCTP deaminase family
IB009_RS23790	COG3093	addiction module antidote protein HigA
IB009_RS23795	COG3549	Plasmid maintenance system killer
IB009_RS23820	COG2974	May be involved in recombination
IB009_RS23930	COG0675	Transposase, IS605 OrfB family
IB009_RS24015	COG1192	Involved in chromosome partitioning
IB009_RS24075	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IB009_RS24105	COG2948	multi-organism process
IB009_RS24155	COG0250	Participates in transcription elongation, termination and antitermination
IB009_RS24210	COG2026	Addiction module toxin, RelE StbE family
IB009_RS24240	COG0463	Glycosyl transferase, family 2