locus-tag class description HQN80_RS00010 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) HQN80_RS00020 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HQN80_RS00025 ENOG4105VP5 Bacterial protein of unknown function (DUF937) HQN80_RS00030 ENOG410667J hydrolase HQN80_RS00035 ENOG410657R replicase EC 2.7 HQN80_RS00040 ENOG4105EMF GntR family transcriptional regulator HQN80_RS00045 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 HQN80_RS00050 ENOG4108RTU Aldolase HQN80_RS00070 ENOG4105D99 atp gtp-binding protein HQN80_RS00075 ENOG4105R2A (LipO)protein HQN80_RS00095 ENOG4105FDP GntR family transcriptional regulator HQN80_RS00100 ENOG4105CI1 PTS System HQN80_RS00115 ENOG4108AHD Transcriptional regulator HQN80_RS00120 ENOG4107RUZ Sss sodium solute transporter superfamily HQN80_RS00125 ENOG4105CBG Sulfatase HQN80_RS00130 ENOG4106DRA Inner membrane protein YidI HQN80_RS00135 ENOG4105VG5 Membrane HQN80_RS00140 ENOG4105JP4 Inner membrane protein yidG HQN80_RS00145 ENOG4105J13 transcriptional regulator HQN80_RS00150 ENOG4105E5M Multidrug resistance protein D HQN80_RS00165 ENOG4105C7K acetolactate synthase HQN80_RS00170 ENOG4105M71 acetolactate synthase 1 regulatory subunit HQN80_RS00175 ENOG4108KX4 response regulator HQN80_RS00180 ENOG4105BZU Histidine kinase HQN80_RS00185 ENOG4105CXY transporter HQN80_RS00190 ENOG4105CXY transporter HQN80_RS00195 ENOG4105CPN adenine deaminase HQN80_RS00200 ENOG4105C7N Xanthine uracil vitamin C permease HQN80_RS00205 ENOG4108SAJ Protein of unknown function (DUF1198) HQN80_RS00215 ENOG4105T8A Uncharacterized protein YicS HQN80_RS00220 ENOG4105D01 (LipO)protein HQN80_RS00225 ENOG4108UZ3 Transporter HQN80_RS00230 ENOG4105S8Q sugar efflux transporter HQN80_RS00245 ENOG4105CT4 transporter HQN80_RS00250 ENOG4105CJQ hydrolase, family 31 HQN80_RS00255 ENOG4105JV1 AsmA family HQN80_RS00260 ENOG4105C2W permease HQN80_RS00265 ENOG4105D6U Sodium Glutamate Symporter HQN80_RS00275 ENOG4105CB5 ATP-dependent DNA helicase recG HQN80_RS00280 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase HQN80_RS00285 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) HQN80_RS00295 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) HQN80_RS00310 ENOG4105EN6 Membrane HQN80_RS00315 ENOG4105F5P DNA-damage-inducible protein d HQN80_RS00320 ENOG4105DSJ YicC domain protein HQN80_RS00335 ENOG4107RRE RNA-directed DNA polymerase HQN80_RS00345 ENOG4108Z1K This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) HQN80_RS00350 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase HQN80_RS00360 ENOG4105KDC 50s ribosomal protein l28 HQN80_RS00380 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase HQN80_RS00385 ENOG4105DKP glycosyl transferase, family 9 HQN80_RS00390 ENOG4107RJ7 Glycosyl transferase (Group 1 HQN80_RS00395 ENOG4107543 (lipo)polysaccharide HQN80_RS00400 ENOG4106AH0 Glycosyl Transferase HQN80_RS00405 ENOG4105X1N Glycosyl transferase family 8 HQN80_RS00415 ENOG4105X1N Glycosyl transferase family 8 HQN80_RS00420 ENOG4105K64 Glycosyl transferase, family 2 HQN80_RS00425 ENOG41068PG O-Antigen polymerase HQN80_RS00430 ENOG4105D16 lipopolysaccharide heptosyltransferase i HQN80_RS00435 ENOG4105XA0 heptosyltransferase ii HQN80_RS00445 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) HQN80_RS00455 ENOG4105K64 Glycosyl transferase, family 2 HQN80_RS00460 ENOG4105PXI polysaccharide deacetylase HQN80_RS00465 ENOG41063SB peptidase HQN80_RS00475 ENOG4107YZP Rhodanese domain protein HQN80_RS00480 ENOG4105VW4 glutaredoxin 3 HQN80_RS00495 ENOG4105D7W serine acetyltransferase HQN80_RS00500 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) HQN80_RS00510 ENOG41073TP transcriptional regulator HQN80_RS00515 ENOG4105DAA L-lactate HQN80_RS00520 ENOG4105EUR Domain-Containing protein HQN80_RS00525 ENOG4108WY4 inner membrane lipoprotein HQN80_RS00530 ENOG4108YYI Protein of unknown function (DUF2810) HQN80_RS00540 ENOG4105E61 Mannitol repressor protein HQN80_RS00550 ENOG4105CTS PTS system mannitol-specific HQN80_RS00555 ENOG4105FP6 Protein of unknown function (DUF3302) HQN80_RS00560 ENOG4105EFX secretion protein, HlyD family HQN80_RS00600 ENOG4108U78 Glutathione S-transferase HQN80_RS00610 ENOG4105EM7 Selenocysteine-specific translation elongation factor HQN80_RS00615 ENOG4105C0A alcohol dehydrogenase HQN80_RS00620 ENOG4105C26 Dehydrogenase HQN80_RS00625 ENOG4105KK7 inner membrane protein YiaW HQN80_RS00630 ENOG4105EFX secretion protein, HlyD family HQN80_RS00635 ENOG4108Q2M Transcriptional regulator HQN80_RS00640 ENOG4105GNX MltA-interacting MipA family protein HQN80_RS00650 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase HQN80_RS00655 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase HQN80_RS00660 ENOG4105H6Q decarboxylase HQN80_RS00670 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit HQN80_RS00675 ENOG4105CG6 trap dicarboxylate transporter dctm subunit HQN80_RS00680 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter HQN80_RS00685 ENOG4108R66 Conserved Protein HQN80_RS00695 ENOG4105J4Q Transcriptional regulator HQN80_RS00700 ENOG4108XIB electron transport protein ysaA HQN80_RS00705 ENOG4105JKW Valine--pyruvate aminotransferase HQN80_RS00710 ENOG4107T9C Alpha amylase catalytic region HQN80_RS00715 ENOG4108UR8 BAX protein HQN80_RS00720 ENOG4105T16 Transcriptional regulator (AraC family) HQN80_RS00725 ENOG4108HWW ABC transporter HQN80_RS00730 ENOG4105C2J ABC transporter HQN80_RS00735 ENOG4105DFW ABC transporter HQN80_RS00745 ENOG4105CMG Carbohydrate kinase HQN80_RS00750 ENOG410688U Inner membrane protein yiaB HQN80_RS00755 ENOG4108Z12 YiaAB two helix domain-containing protein HQN80_RS00760 ENOG4105MEV Acyl-transferase HQN80_RS00780 ENOG41060TC Hok gef cell toxic protein HQN80_RS00790 ENOG4105MVF Transcriptional regulator HQN80_RS00795 ENOG4106JH6 (LipO)protein HQN80_RS00805 ENOG4108ZG0 Ompa motb domain protein HQN80_RS00810 ENOG4107QY8 reductase HQN80_RS00815 ENOG4105HNP -acetyltransferase HQN80_RS00820 ENOG4108R3E Dna-3-methyladenine glycosylase i HQN80_RS00825 ENOG4105EAX Putative lipase HQN80_RS00830 ENOG4105FCD Major Facilitator HQN80_RS00835 ENOG4105DIJ Phosphoethanolamine transferase HQN80_RS00850 ENOG4105DEF Extracellular solute-binding protein, family 5 HQN80_RS00855 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HQN80_RS00860 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HQN80_RS00865 ENOG4105C3U ABC transporter HQN80_RS00870 ENOG4108JQ7 (ABC) transporter HQN80_RS00875 ENOG4105C44 Serine transporter HQN80_RS00900 ENOG4105D1V cellulose synthase operon protein YhjU HQN80_RS00905 ENOG4105WQA Cellulose biosynthesis protein BcsF HQN80_RS00910 ENOG4105U74 cellulose biosynthesis protein BcsE HQN80_RS00915 ENOG410661M cytoplasmic protein HQN80_RS00925 ENOG4107QZ7 Cellulose synthase catalytic subunit HQN80_RS00930 ENOG4107EEX Cellulose synthase regulator protein HQN80_RS00935 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) HQN80_RS00940 ENOG4105EJG cellulose synthase HQN80_RS00945 ENOG4105BZU Histidine kinase HQN80_RS00955 ENOG4105CS0 peptidase HQN80_RS00965 ENOG4105CMB EAL domain-containing protein HQN80_RS00970 ENOG41066T0 asmA family HQN80_RS00975 ENOG4105CSH Transporter HQN80_RS00980 ENOG4107H3J ribonuclease HQN80_RS00985 ENOG4105CBN LysR family transcriptional regulator HQN80_RS00990 ENOG4106S2D Transcriptional regulator HQN80_RS01000 ENOG4105CA0 peroxidase HQN80_RS01005 ENOG4105CVK Glutamate decarboxylase HQN80_RS01010 ENOG4108NKV transcriptional regulator HQN80_RS01020 ENOG4105BZS acriflavin resistance protein HQN80_RS01025 ENOG4105C1P efflux transporter, rnd family, mfp subunit HQN80_RS01035 ENOG4106WJ0 Regulates the expression of several genes involved in acid resistance. Required for the expression of gadA and gadBC, among others, regardless of media or growth conditions. Binds directly to the 20 bp GAD box found in the control regions of both loci HQN80_RS01040 ENOG4108YK4 Acid-resistance membrane protein HQN80_RS01045 ENOG41060V2 Acid-resistance protein HQN80_RS01050 ENOG4105XXV Acid-resistance protein HQN80_RS01055 ENOG4105KT7 mgtC SapB transporter HQN80_RS01065 ENOG4105Y4Z Outer Membrane Lipoprotein HQN80_RS01075 ENOG4105K89 arsenate reductase HQN80_RS01080 ENOG4107R5R arsenical pump membrane protein HQN80_RS01085 ENOG4105KBH arsR family transcriptional regulator HQN80_RS01095 ENOG4105DC8 reductase HQN80_RS01100 ENOG4105D6S protein involved in catabolism of external DNA HQN80_RS01105 ENOG4105DGW oligopeptidase A HQN80_RS01115 ENOG4105DUX Transporter HQN80_RS01130 ENOG4105CJ3 phosphate transporter HQN80_RS01135 ENOG4105CBX hi0933 family HQN80_RS01215 ENOG410624V efflux system protein HQN80_RS01245 ENOG4105DR5 peptidase HQN80_RS01255 ENOG4105E3B Multicopper oxidase HQN80_RS01260 ENOG4105VR0 copper resistance HQN80_RS01265 ENOG4105JDN Copper resistance protein HQN80_RS01270 ENOG4108PG2 copper resistance HQN80_RS01275 ENOG4105CK6 Two component transcriptional regulator (Winged helix family HQN80_RS01280 ENOG4105GR3 Histidine kinase HQN80_RS01290 ENOG4107UNS conserved inner membrane protein HQN80_RS01305 ENOG4105D0S secretion protein (HlyD HQN80_RS01310 ENOG4105CJ1 ABC, transporter HQN80_RS01315 ENOG4105CMI transporter HQN80_RS01340 ENOG4106665 Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) HQN80_RS01345 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HQN80_RS01350 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HQN80_RS01355 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein HQN80_RS01360 ENOG4107YAK holo-(acyl carrier protein) synthase 2 HQN80_RS01365 ENOG4105DSF transport protein HQN80_RS01370 ENOG4105F9N Major Facilitator Superfamily HQN80_RS01375 ENOG4108W1V Lipoprotein HQN80_RS01380 ENOG4105EX9 Membrane HQN80_RS01395 ENOG4107FS9 Membrane HQN80_RS01405 ENOG4105MG3 Membrane HQN80_RS01410 ENOG4106H78 methyltransferase HQN80_RS01415 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) HQN80_RS01420 ENOG4105CAK Cell division ATP-binding protein ftsE HQN80_RS01425 ENOG4105CRP Part of the ABC transporter FtsEX involved in HQN80_RS01430 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HQN80_RS01435 ENOG4105CP9 extracellular ligand-binding receptor HQN80_RS01450 ENOG4105U59 -acetyltransferase HQN80_RS01455 ENOG4105CP9 extracellular ligand-binding receptor HQN80_RS01460 ENOG4105C32 Amino acid ABC transporter (Permease) HQN80_RS01465 ENOG4105CF8 branched-chain amino acid ABC transporter, permease HQN80_RS01470 ENOG4105C0Z ABC transporter HQN80_RS01475 ENOG4108IV0 ABC, transporter HQN80_RS01480 ENOG4105BZ7 extracellular solute-binding protein family 1 HQN80_RS01485 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component HQN80_RS01490 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component HQN80_RS01500 ENOG4107T6V glycerophosphoryl diester phosphodiesterase HQN80_RS01505 ENOG4105WC8 Conserved Protein HQN80_RS01510 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) HQN80_RS01515 ENOG4106FA4 HQN80_RS01520 ENOG4105WCN acetyltransferase HQN80_RS01525 ENOG4105D9R oxidoreductase HQN80_RS01530 ENOG4105C2I pirin domain protein HQN80_RS01535 ENOG4105DIQ Transcriptional regulator HQN80_RS01540 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family HQN80_RS01545 ENOG4105C6Z Gluconate HQN80_RS01550 ENOG41076UM multiple antibiotic resistance (MarC)-related protein HQN80_RS01555 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) HQN80_RS01580 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) HQN80_RS01605 ENOG4105C6V Glycerol-3-phosphate dehydrogenase HQN80_RS01620 ENOG4105E98 transcriptional regulator DeoR family HQN80_RS01625 ENOG4105CYB regulatoR HQN80_RS01630 ENOG4105E0Y RtcB Protein HQN80_RS01645 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) HQN80_RS01650 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) HQN80_RS01655 ENOG4105C6Z Gluconate HQN80_RS01665 ENOG4105MJ2 Competence protein HQN80_RS01675 ENOG4105DNE Transposase HQN80_RS01685 ENOG4105CE1 Ferrous iron transport protein b HQN80_RS01690 ENOG4105XFK Ferrous iron transport protein A HQN80_RS01695 ENOG4105BZM domain protein HQN80_RS01700 ENOG4108RRZ Transcription elongation factor GreB HQN80_RS01710 ENOG4105E0F Histidine kinase HQN80_RS01720 ENOG4108MAJ Membrane HQN80_RS01730 ENOG4105VEJ Heat shock protein HQN80_RS01735 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 HQN80_RS01740 ENOG4105DQY intracellular growth attenuator HQN80_RS01745 ENOG4107RK2 ADP-ribose diphosphatase NudE HQN80_RS01750 ENOG4108JQC penicillin-binding protein 1A HQN80_RS01755 ENOG4108U1Q Pilus assembly protein HQN80_RS01760 ENOG41065NF Fimbrial assembly family protein HQN80_RS01765 ENOG4105XPX DNA utilization protein HofO HQN80_RS01770 ENOG4105ITY Required for the use of extracellular DNA as a nutrient HQN80_RS01775 ENOG4105E4G Type IV pilus HQN80_RS01790 ENOG4105EGB membrane protein DamX HQN80_RS01795 ENOG4105DFE Dna adenine methylase HQN80_RS01800 ENOG4105DJV ribulose-phosphate 3-epimerase HQN80_RS01805 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) HQN80_RS01810 ENOG4105C31 Tryptophanyl-tRNA synthetase HQN80_RS01815 ENOG4108M21 HQN80_RS01820 ENOG4105RMW regulation of transcription, DNA-dependent HQN80_RS01825 ENOG4108626 Racemase HQN80_RS01830 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) HQN80_RS01835 ENOG41080QX K07048 phosphotriesterase-related protein HQN80_RS01840 ENOG4105MUZ Protein of unknown function DUF2620 HQN80_RS01845 ENOG4106M0N transport system permease protein HQN80_RS01850 ENOG4106PKC pyridoxal phosphate binding HQN80_RS01855 ENOG4105FDP GntR family transcriptional regulator HQN80_RS01860 ENOG4108KPW sugar kinase HQN80_RS01865 ENOG4107Y0V Not clear, may be involved in an isomerization step HQN80_RS01870 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine HQN80_RS01875 ENOG4107QHQ amino acid HQN80_RS01880 ENOG4105VYH HQN80_RS01890 ENOG4107V9H nitrite transporter HQN80_RS01895 ENOG4105WZK nitrite reductase NADPH small subunit HQN80_RS01900 ENOG4107QZF nitrite reductase NADPH large subunit HQN80_RS01910 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) HQN80_RS01920 ENOG4105MZU cell filamentation protein HQN80_RS01925 ENOG4105DDQ anthranilate synthase HQN80_RS01930 ENOG4105C8Y Acetylornithine aminotransferase HQN80_RS01935 ENOG410613R integral membrane protein, YccS YhfK family HQN80_RS01945 ENOG4108UKZ OsmC family HQN80_RS01950 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) HQN80_RS01960 ENOG4105DNZ Alpha Beta Hydrolase HQN80_RS01965 ENOG4105C5H ABC transporter HQN80_RS01980 ENOG4105VKU nucleicacid-binding protein HQN80_RS01985 ENOG4108YZY peptidylprolyl cis-trans isomerase HQN80_RS01995 ENOG4108V1T peptidylprolyl cis-trans isomerase HQN80_RS02000 ENOG4105WWK YheO domain protein HQN80_RS02040 ENOG4108NNZ chitinase HQN80_RS02045 ENOG4105W53 bacterioferritin-associated ferredoxin HQN80_RS02050 ENOG4108UQY Iron-storage protein HQN80_RS02055 ENOG4105EHH Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity) HQN80_RS02065 ENOG41063JA Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity) HQN80_RS02070 ENOG4105R04 type II secretion system protein K HQN80_RS02085 ENOG41069X0 general secretion pathway protein h HQN80_RS02090 ENOG4108VAU general secretion pathway protein G HQN80_RS02095 ENOG4105D7Q type ii secretion system HQN80_RS02100 ENOG4107QHF type ii secretion system protein e HQN80_RS02105 ENOG4105GVR general secretion pathway protein D HQN80_RS02110 ENOG4107KSE General secretion pathway protein C HQN80_RS02115 ENOG410899B May play a regulatory role under conditions of derepressed gsp gene expression HQN80_RS02120 ENOG4107ACA Calcium-binding protein required for initiation of chromosome replication HQN80_RS02140 ENOG41080KG One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) HQN80_RS02185 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) HQN80_RS02230 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) HQN80_RS02235 ENOG41067V7 50S ribosomal protein L36 HQN80_RS02265 ENOG4105VTS DnaJ-like, subfamily C HQN80_RS02270 ENOG4105W1Y Transcriptional regulator HQN80_RS02275 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system HQN80_RS02285 ENOG4105C1A potassium transporter peripheral membrane HQN80_RS02305 ENOG4105C79 DNA protecting protein DprA HQN80_RS02315 ENOG4108WI1 Dna topoisomerase HQN80_RS02330 ENOG4105SG3 Protein of unknown function (DUF1488) HQN80_RS02335 ENOG4108Z0R Transferase HQN80_RS02375 ENOG4105CDA abc transporter atp-binding protein HQN80_RS02380 ENOG4105DRP amino acid AbC transporter HQN80_RS02385 ENOG4105EZ7 amino acid ABC transporter HQN80_RS02395 ENOG4105XCM membrane LIPOPROTEIN HQN80_RS02400 ENOG4105BZS acriflavin resistance protein HQN80_RS02405 ENOG4105C1P efflux transporter, rnd family, mfp subunit HQN80_RS02410 ENOG4108XG4 DNA-binding transcriptional regulator HQN80_RS02415 ENOG41061ME transport protein HQN80_RS02420 ENOG4105CEC DNA methylase N-4 N-6 HQN80_RS02430 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) HQN80_RS02440 ENOG4108IA2 Sodium pantothenate symporter HQN80_RS02445 ENOG4105RG0 Membrane HQN80_RS02450 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase HQN80_RS02455 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein HQN80_RS02460 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family HQN80_RS02465 ENOG41062P1 Diguanylate cyclase phosphodiesterase HQN80_RS02475 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) HQN80_RS02480 ENOG4105VQ7 Rod shape-determining protein MreD HQN80_RS02490 ENOG4105C03 ribonuclease HQN80_RS02495 ENOG4105QD6 exported protein HQN80_RS02500 ENOG4105D1U peptidase U62 modulator of DNA gyrase HQN80_RS02505 ENOG4105CR8 Transcriptional regulator HQN80_RS02510 ENOG4105ZQC membrane protein AaeX HQN80_RS02525 ENOG4105UNR (Barnase) inhibitor HQN80_RS02530 ENOG4105RID UPF0379 protein yhcN HQN80_RS02545 ENOG4105C0H protease HQN80_RS02550 ENOG4105C0H protease HQN80_RS02555 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III HQN80_RS02560 ENOG4105D6Z AFG1 family ATPase HQN80_RS02575 ENOG4107MKT Stringent starvation protein a HQN80_RS02580 ENOG4105KB2 stringent starvation protein b HQN80_RS02585 ENOG4105CEE C4-dicarboxylate transporter HQN80_RS02590 ENOG4108QBF Transcriptional regulator HQN80_RS02615 ENOG4108R66 Conserved Protein HQN80_RS02620 ENOG4105DFS Conserved Protein HQN80_RS02625 ENOG4105BZ8 glutamate synthase HQN80_RS02630 ENOG4105CBC glutamate synthase HQN80_RS02635 ENOG4105N5T Radical SAM Protein HQN80_RS02640 ENOG4105BZU Histidine kinase HQN80_RS02645 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain HQN80_RS02655 ENOG4108NIH transferase activity, transferring phosphorus-containing groups HQN80_RS02660 ENOG41080Z8 PHOSPHOCARRIER protein HQN80_RS02670 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN HQN80_RS02675 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA HQN80_RS02680 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HQN80_RS02685 ENOG4108IUZ ABC transporter HQN80_RS02690 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA HQN80_RS02695 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) HQN80_RS02705 ENOG4105C2X Arabinose 5-phosphate isomerase HQN80_RS02710 ENOG4105FEU K -dependent Na -Ca exchanger HQN80_RS02715 ENOG4105DHJ ABC, transporter HQN80_RS02720 ENOG4105CY3 ABC transporter, permease HQN80_RS02725 ENOG4107PE3 Mammalian cell entry related domain protein HQN80_RS02730 ENOG4105E3I toluene tolerance HQN80_RS02735 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane HQN80_RS02740 ENOG4105VFK BolA family HQN80_RS02750 ENOG4105HVQ Regulatory factor of maltose metabolism HQN80_RS02755 ENOG4105EAH synthase HQN80_RS02770 ENOG4105QYV Membrane HQN80_RS02780 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase HQN80_RS02785 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) HQN80_RS02790 ENOG4105HBR Rna-binding protein HQN80_RS02800 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) HQN80_RS02805 ENOG4105EEI dihydropteroate synthase HQN80_RS02815 ENOG4105NTZ Preprotein translocase subunit SecG HQN80_RS02845 ENOG4105CHV Transcription elongation factor NusA HQN80_RS02885 ENOG4105C1J atp-dependent rna helicase HQN80_RS02890 ENOG4105CIC tryptophan-specific transport protein HQN80_RS02895 ENOG4105DEN Luciferase family HQN80_RS02915 ENOG4108YYD acetyltransferase HQN80_RS02930 ENOG4107R7Y intracellular protease Pfpi family HQN80_RS02935 ENOG4105K4T epimerase HQN80_RS02940 ENOG4107S21 permease HQN80_RS02945 ENOG4105W4M Transport-associated protein HQN80_RS02965 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) HQN80_RS02970 ENOG4105I74 Fimbrial protein HQN80_RS02985 ENOG4108VCD Chaperone HQN80_RS02990 ENOG4105Q10 Fimbrial-like protein HQN80_RS02995 ENOG4106HBN Galactosamine-6-phosphate isomerase HQN80_RS03000 ENOG4105F3R pts system mannose fructose sorbose family iid HQN80_RS03005 ENOG4105ETZ PTS System HQN80_RS03010 ENOG4108UZY PTS System HQN80_RS03020 ENOG4105E70 isomerase HQN80_RS03025 ENOG4105CE4 GlcNAc 6-P deacetylase HQN80_RS03030 ENOG4108YTN IIa component HQN80_RS03035 ENOG4105F3R pts system mannose fructose sorbose family iid HQN80_RS03045 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB HQN80_RS03055 ENOG4105E98 transcriptional regulator DeoR family HQN80_RS03060 ENOG4108R8Z these effects are overcome by concomitant expression of antitoxin SohA (PrlF). Massive overexpression is toxic. Unlike most other characterized TA systems degrades rRNA, and co-folding of the proteins is necessary in vitro for inhibition of the RNase activity. It is not known if it has any sequence-specificity. Acts as a transcription factor. The YhaV PrlF complex binds the prlF-yhaV operon, probably negatively regulating its expression HQN80_RS03065 ENOG4105ZEG Suppressor protein HQN80_RS03070 ENOG4105CTX dehydratase HQN80_RS03075 ENOG4105DJB Major Facilitator Superfamily HQN80_RS03085 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase HQN80_RS03090 ENOG4105BZW Glycerate kinase HQN80_RS03115 ENOG410811B TRANSCRIPTIONal HQN80_RS03120 ENOG4105C7B Threonine dehydratase HQN80_RS03130 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) HQN80_RS03135 ENOG4105C6N Formate acetyltransferase HQN80_RS03140 ENOG4105KME endoribonuclease L-psp HQN80_RS03145 ENOG4105EJQ L-serine dehydratase HQN80_RS03150 ENOG4105C44 Serine transporter HQN80_RS03160 ENOG4106D80 Uncharacterized protein YhaL HQN80_RS03165 ENOG4108CNN domain protein HQN80_RS03170 ENOG4105CWB LysR family transcriptional Regulator HQN80_RS03175 ENOG4105KAF membrAne HQN80_RS03180 ENOG4105KAF membrAne HQN80_RS03185 ENOG4105CHF Glutathione S-transferase HQN80_RS03190 ENOG4108VBZ doxx family HQN80_RS03195 ENOG4105YJD HQN80_RS03200 ENOG41090KG Inner membrane protein YqjE HQN80_RS03205 ENOG4105NE1 Conserved Protein HQN80_RS03210 ENOG4105WAY exported protein HQN80_RS03215 ENOG4105IYR Modulates the activity of the EnvZ OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR (By similarity) HQN80_RS03220 ENOG4106W5V Membrane HQN80_RS03225 ENOG4107YCY Transcriptional regulator HQN80_RS03250 ENOG4105DPW Major facilitator superfamily MFS_1 HQN80_RS03260 ENOG4105CTX dehydratase HQN80_RS03265 ENOG4105P66 Membrane HQN80_RS03270 ENOG4107QV7 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity) HQN80_RS03275 ENOG4105DU1 integral membrane protein, terc HQN80_RS03280 ENOG4105EE0 oxidoreductase HQN80_RS03285 ENOG4108UB4 uncharacterized protein ygjQ HQN80_RS03290 ENOG4108VKG metal-dependent hydrolase HQN80_RS03300 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase HQN80_RS03305 ENOG4107WCA isomerase HQN80_RS03310 ENOG4107W6W Conserved Protein HQN80_RS03315 ENOG4105E5D amino acid HQN80_RS03320 ENOG4105FK9 beta-D-galactosidase beta subunit HQN80_RS03325 ENOG4105CNT hydrolase family 2 HQN80_RS03330 ENOG4105CQ4 Transcriptional regulator HQN80_RS03335 ENOG4108Y51 tRNA-binding protein HQN80_RS03345 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor HQN80_RS03350 ENOG4105NTW Transcriptional regulator HQN80_RS03355 ENOG4105Q26 Siderophore-interacting protein HQN80_RS03370 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HQN80_RS03375 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) HQN80_RS03385 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) HQN80_RS03390 ENOG4107QPK )-transporter HQN80_RS03395 ENOG4107GFK fumarate HQN80_RS03400 ENOG4106DSS Tartrate dehydratase subunit alpha HQN80_RS03405 ENOG4105EJC lysr family transcriptional regulator HQN80_RS03415 ENOG4107ZVW dihydroneopterin aldolase HQN80_RS03430 ENOG4106MWK domain protein HQN80_RS03435 ENOG4105I7R Adenylate cyclase HQN80_RS03440 ENOG4105CE6 Adenylation and deadenylation of glutamate--ammonia ligase (By similarity) HQN80_RS03465 ENOG4105PV3 Inner membrane protein yqiJ HQN80_RS03475 ENOG4108MY7 Fimbrial HQN80_RS03480 ENOG4108TTM chaperone HQN80_RS03490 ENOG4105H8W Fimbrial protein HQN80_RS03495 ENOG4105W0Z cytoplasmic protein HQN80_RS03515 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b HQN80_RS03520 ENOG4106032 Glutathionylspermidine synthase HQN80_RS03530 ENOG4105DFG type I secretion outer membrane protein HQN80_RS03535 ENOG41087AY ADP-Ribose pyrophosphatase HQN80_RS03540 ENOG4108SX3 cytoplasmic protein HQN80_RS03545 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) HQN80_RS03550 ENOG4105IPS esterase HQN80_RS03555 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HQN80_RS03560 ENOG4105VRH Antibiotic biosynthesis monooxygenase HQN80_RS03565 ENOG4105NF4 modulator of drug activity HQN80_RS03575 ENOG4107DEU Inner membrane protein YgiZ HQN80_RS03580 ENOG4105DHQ Histidine kinase HQN80_RS03585 ENOG4105XJC Two component transcriptional regulator (Winged helix family HQN80_RS03590 ENOG4105H4F exported protein HQN80_RS03595 ENOG4105F4I Transcriptional regulator HQN80_RS03600 ENOG4105RT5 Toxic component of a toxin-antitoxin (TA) module. An mRNA interferase which has been reported to be translation- independent (PubMed 19690171, PubMed 19943910) and translation- dependent (PubMed 20041169). Cleavage has been reported to occur on either side of G in the sequence GCU (PubMed 19690171) but also after C in GC(A U) sequences (PubMed 19943910). There are only 14 genes in E.coli W3110 (and probably also MG1655) that do not have a GCU sequence and thus are resistant to the mRNA interferase activity. Overexpression causes cessation of cell growth and inhibits cell proliferation via inhibition of translation as well as increasing persister cell formation HQN80_RS03605 ENOG4105WJ3 XRE family Transcriptional regulator HQN80_RS03610 ENOG4108J59 Extracellular solute-binding protein, family 5 HQN80_RS03615 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HQN80_RS03620 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase HQN80_RS03625 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) HQN80_RS03630 ENOG4105CCT upf0313 protein HQN80_RS03640 ENOG4105ZKC Conserved Protein HQN80_RS03645 ENOG4105CV8 reductase HQN80_RS03650 ENOG4108I6A alcohol dehydrogenase HQN80_RS03655 ENOG4105CF7 AraC family transcriptional regulator HQN80_RS03660 ENOG4108K81 inner membrane protein YghB HQN80_RS03665 ENOG4105C28 cystathionine HQN80_RS03670 ENOG4105CWK Biopolymer transport protein, ExbB HQN80_RS03675 ENOG4108ZZF transport protein (ExbD) HQN80_RS03680 ENOG4105CYX Short-chain dehydrogenase reductase Sdr HQN80_RS03690 ENOG4105CPC Aldo Keto reductase HQN80_RS03700 ENOG410900S Protein of unknown function (DUF2623) HQN80_RS03705 ENOG4105E3S small subunit HQN80_RS03710 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HQN80_RS03715 ENOG4105CJ5 hydrogenase 2 b cytochrome subunit HQN80_RS03720 ENOG4105DPX Hydrogenase, large subunit HQN80_RS03725 ENOG4108USZ hydrogenase HQN80_RS03730 ENOG4108WGS hydrogenase 2-specific chaperone HQN80_RS03740 ENOG41082MF Hydrogenase assembly chaperone hypC hupF HQN80_RS03745 ENOG4105CYM Glutathione S-transferase HQN80_RS03750 ENOG4106032 Glutathionylspermidine synthase HQN80_RS03755 ENOG4105CJ3 phosphate transporter HQN80_RS03760 ENOG4108GH0 ATP-binding protein yghT HQN80_RS03765 ENOG4108NDC ATP-binding protein yghS HQN80_RS03775 ENOG4106FPV ATP-binding protein YghR HQN80_RS03780 ENOG4108S55 polysaccharide biosynthesis protein HQN80_RS03790 ENOG4108UUE Transcriptional regulator HQN80_RS03795 ENOG4108M8S permease YjgP YjgQ family protein HQN80_RS03805 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) HQN80_RS03810 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) HQN80_RS03820 ENOG4107RCI amp-dependent synthetase and ligase HQN80_RS03830 ENOG4108KWP DNA-binding transcriptional regulator GlcC HQN80_RS03835 ENOG4105CQB FAD linked oxidase domain protein HQN80_RS03840 ENOG4105EU8 FAD linked oxidase domain protein HQN80_RS03845 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) HQN80_RS03850 ENOG4108ZJF Glcg protein HQN80_RS03855 ENOG4107QP3 malate synthase g HQN80_RS03860 ENOG4105DAA L-lactate HQN80_RS03885 ENOG4105U1E general secretion pathway protein M HQN80_RS03895 ENOG4108UQV Membrane HQN80_RS03900 ENOG4105CXN decarboxylase HQN80_RS03905 ENOG4105EAA nucleoside HQN80_RS03920 ENOG4105CEN a g-specific adenine glycosylase HQN80_RS03930 ENOG41090ED Protein with unknown function (DUF469) HQN80_RS03935 ENOG4105K33 Periplasmic Protein HQN80_RS03940 ENOG4105HDK L-asparaginase HQN80_RS03945 ENOG4106MH3 alpha helix chain HQN80_RS03950 ENOG4105CSA Coproporphyrinogen iii oxidase HQN80_RS03955 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) HQN80_RS03965 ENOG4108VIA integral membrane protein HQN80_RS03970 ENOG4105DFA alanine racemase domain protein HQN80_RS03975 ENOG4105CZX twitching motility protein HQN80_RS03990 ENOG4105D7Z glutathione synthase HQN80_RS03995 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) HQN80_RS04000 ENOG4105RWS endonuclease I HQN80_RS04010 ENOG4107QNK )-transporter HQN80_RS04030 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) HQN80_RS04045 ENOG4108K0D peptidase, M48 HQN80_RS04050 ENOG4105CV1 Transketolase (EC 2.2.1.1) HQN80_RS04055 ENOG4108X7Y Mannitol-specific cryptic phosphotransferase enzyme iia HQN80_RS04065 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein HQN80_RS04070 ENOG4108Q8A Fructose-1,6-bisphosphatase HQN80_RS04075 ENOG4108R4K DNA-binding, transcriptional regulator HQN80_RS04080 ENOG4107Z1W Fructose transport system kinase HQN80_RS04085 ENOG4108JJB ABC transporter HQN80_RS04090 ENOG4108JJB ABC transporter HQN80_RS04120 ENOG4105D2N Aldolase HQN80_RS04125 ENOG4105D64 Mechanosensitive ion channel HQN80_RS04130 ENOG4108ZUB Lysine exporter protein (Lyse ygga) HQN80_RS04135 ENOG4105MPN Membrane HQN80_RS04140 ENOG4105DEQ transcriptional regulator HQN80_RS04145 ENOG4105CYC Transferase HQN80_RS04150 ENOG4108M7F enoyl-CoA hydratase isomerase HQN80_RS04155 ENOG4105DJT lAO AO transport system ATPase HQN80_RS04160 ENOG4105D5P Methylmalonyl-coA mutase HQN80_RS04180 ENOG4108JQ1 Dehydrogenase HQN80_RS04195 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase HQN80_RS04215 ENOG4107RAQ aminopeptidase HQN80_RS04220 ENOG4105D0A hydroxylase HQN80_RS04225 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family HQN80_RS04255 ENOG4105CS2 ec 3.2.1.21 HQN80_RS04265 ENOG4108UT2 hemolysin iii HQN80_RS04275 ENOG4105Y75 tpr repeat protein HQN80_RS04280 ENOG4108YDB Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB HQN80_RS04285 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) HQN80_RS04290 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) HQN80_RS04295 ENOG4105T95 Thiol disulfide interChange protein HQN80_RS04300 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) HQN80_RS04330 ENOG4105C2W permease HQN80_RS04335 ENOG4105BZ8 glutamate synthase HQN80_RS04340 ENOG4108R8B oxidoreductase Fe-S subunit HQN80_RS04345 ENOG4105C7N Xanthine uracil vitamin C permease HQN80_RS04350 ENOG4107QUY Guanine deaminase HQN80_RS04355 ENOG4105C2W permease HQN80_RS04360 ENOG4105C7W Xanthine dehydrogenase HQN80_RS04365 ENOG410873Y FAD binding domain in molybdopterin dehydrogenase HQN80_RS04370 ENOG4107UUR Chlorohydrolase aminohydrolase HQN80_RS04375 ENOG4105BZ8 glutamate synthase HQN80_RS04380 ENOG4105MFX 4-diphosphocytidyl-2c-methyl-d-erythritol synthase HQN80_RS04385 ENOG4105MJ6 selenium-dependent hydroxylase accessory protein YqeC HQN80_RS04390 ENOG4107P0T Selenium-dependent molybdenum hydroxylase system protein, YqeB family HQN80_RS04395 ENOG4105C5B carbamate kinase HQN80_RS04405 ENOG4107S4Y M20 DapE family protein YgeY HQN80_RS04410 ENOG4107RCH Diaminopropionate ammonia-lyase HQN80_RS04415 ENOG4105IW6 Carbamoyltransferase HQN80_RS04420 ENOG4108JUB Transcriptional regulator HQN80_RS04425 ENOG4108UTP (2Fe-2S)-binding domain protein HQN80_RS04430 ENOG4108HR6 Dehydrogenase HQN80_RS04435 ENOG4105C7W Xanthine dehydrogenase HQN80_RS04440 ENOG4108K5P (LipO)protein HQN80_RS04450 ENOG4108T88 HQN80_RS04490 ENOG41075IY surface presentation of antigens protein SpaP HQN80_RS04495 ENOG4105U07 type iii secretion HQN80_RS04500 ENOG4108TN6 type iii secretion HQN80_RS04505 ENOG4108M6W surface presentation of antigens protein SpaS HQN80_RS04510 ENOG4108M6W surface presentation of antigens protein SpaS HQN80_RS04515 ENOG4108M6W surface presentation of antigens protein SpaS HQN80_RS04530 ENOG4108RC9 Type III secretion system protein HQN80_RS04545 ENOG4108RBT type iii secretion HQN80_RS04580 ENOG4108YAB Invasion protein HQN80_RS04605 ENOG4105FV3 HQN80_RS04610 ENOG4108TC1 Transcriptional regulator HQN80_RS04615 ENOG4105ISV protein with bipartite regulator domain HQN80_RS04620 ENOG4108MHD transport protein HQN80_RS04625 ENOG4105CHU acetyl-coa acetyltransferase HQN80_RS04635 ENOG4105CHR reductase HQN80_RS04640 ENOG4107QNK )-transporter HQN80_RS04650 ENOG4105RQF LysR family Transcriptional regulator HQN80_RS04660 ENOG41060NJ transcriptional regulator HQN80_RS04665 ENOG4105CEY Amp-dependent synthetase and ligase HQN80_RS04670 ENOG4107S74 Lysophospholipid transporter LplT HQN80_RS04675 ENOG4105CPC Aldo Keto reductase HQN80_RS04680 ENOG4105SUV lipoprotein YgdR HQN80_RS04685 ENOG4105EE5 Membrane protein terC HQN80_RS04700 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase HQN80_RS04715 ENOG4105IPU prepilin peptidase dependent protein A HQN80_RS04720 ENOG4105JCS prepilin peptidase dependent protein HQN80_RS04725 ENOG4105SEN Protein of unknown function (DUF2509) HQN80_RS04730 ENOG4105RVB Prepilin peptidase dependent protein c HQN80_RS04735 ENOG4105DSY exodeoxyribonuclease V, gamma HQN80_RS04740 ENOG4107QXK peptidase HQN80_RS04745 ENOG4107QKA exodeoxyribonuclease V beta HQN80_RS04750 ENOG4107QYX exodeoxyribonuclease v alpha HQN80_RS04755 ENOG4108EKC n-acetylglutamate synthase HQN80_RS04760 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase HQN80_RS04780 ENOG4105CA3 membrane-bound lytic murein transglycosylase HQN80_RS04785 ENOG4105CUZ uba thif-type nad fad binding protein HQN80_RS04790 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) HQN80_RS04795 ENOG4105C9B Cysteine desulfurase HQN80_RS04800 ENOG4105M5B (LipO)protein HQN80_RS04805 ENOG4105ETT transcriptional Regulator, LysR family HQN80_RS04810 ENOG4105M08 Membrane HQN80_RS04820 ENOG4107EDW L-fucose operon activator HQN80_RS04830 ENOG4105CMG Carbohydrate kinase HQN80_RS04840 ENOG4105EDR glucose galactose transporter HQN80_RS04845 ENOG4107W7X Aldolase HQN80_RS04850 ENOG4105C0A alcohol dehydrogenase HQN80_RS04860 ENOG4105EJQ L-serine dehydratase HQN80_RS04865 ENOG4105C44 Serine transporter HQN80_RS04870 ENOG4105EWT decarboxylase family HQN80_RS04885 ENOG4105WP7 tRNA pseudouridine synthase C HQN80_RS04890 ENOG4105DR9 pseudouridine synthase HQN80_RS04895 ENOG4105QDK Flavodoxin HQN80_RS04900 ENOG4105DJB Major Facilitator Superfamily HQN80_RS04905 ENOG4105EQX glucarate dehydratase HQN80_RS04910 ENOG4105EQX glucarate dehydratase HQN80_RS04915 ENOG4105BZU Histidine kinase HQN80_RS04920 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) HQN80_RS04925 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) HQN80_RS04930 ENOG4106A2Z transcriptional regulator antitoxin, MazE HQN80_RS04935 ENOG4105MZG transcriptional modulator of maze toxin, mazf HQN80_RS04940 ENOG4105DXN mazG family HQN80_RS04955 ENOG4105HA9 of methanol dehydrogenase type HQN80_RS04965 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) HQN80_RS04970 ENOG4108CWB sugar kinase ygcE HQN80_RS04975 ENOG4108ITV Inner membrane protein yqcE HQN80_RS04980 ENOG4105CHR reductase HQN80_RS04985 ENOG4107R3A FAD linked oxidase domain protein HQN80_RS04990 ENOG4105C54 Major Facilitator superfamily HQN80_RS04995 ENOG4106IKH Electron transfer flavoprotein HQN80_RS05000 ENOG4105YBM electron transfer flavoprotein subunit ygcQ HQN80_RS05005 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator HQN80_RS05010 ENOG4105WQV ferredoxin-like protein HQN80_RS05015 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase HQN80_RS05020 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase HQN80_RS05040 ENOG4107635 Hok Gef family protein HQN80_RS05045 ENOG4105F5W AtP-binding protein HQN80_RS05050 ENOG4105D70 Integrase catalytic subunit HQN80_RS05055 ENOG4108SER Transposase HQN80_RS05070 ENOG4108VWQ crispr-associated protein HQN80_RS05080 ENOG4105TZK CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) HQN80_RS05085 ENOG4105PWE CRISPR-associated protein cas2 HQN80_RS05090 ENOG4108MXK alkaline phosphatase isozyme conversion HQN80_RS05095 ENOG4105C11 sulfate adenylyltransferase), subunit 2 HQN80_RS05100 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) HQN80_RS05110 ENOG4105N0Z inner membrane protein ygbE HQN80_RS05145 ENOG4108K5P (LipO)protein HQN80_RS05150 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HQN80_RS05155 ENOG4105C6Z Gluconate HQN80_RS05160 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) HQN80_RS05165 ENOG4105FB2 class II Aldolase HQN80_RS05170 ENOG4105G63 Type III effector Hrp-dependent HQN80_RS05175 ENOG4105ZXK Dehydrogenase HQN80_RS05180 ENOG4105MVE transcriptional regulator HQN80_RS05185 ENOG4105MEW serine threonine protein phosphatase HQN80_RS05200 ENOG4105VXR cytoplasmic protein HQN80_RS05205 ENOG4108JUA Transcriptional regulator HQN80_RS05210 ENOG4105C45 hydrogenase expression formation protein (HypE) HQN80_RS05215 ENOG4105CQS hydrogenase expression formation protein HypD HQN80_RS05220 ENOG41083WG hydrogenase assembly chaperone HQN80_RS05225 ENOG4107RSS Hydrogenase accessory protein HypB HQN80_RS05230 ENOG410816D Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) HQN80_RS05235 ENOG4108VRC Formate hydrogenlyase regulatory protein hycA HQN80_RS05240 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) HQN80_RS05245 ENOG4107R30 NADH dehydrogenase HQN80_RS05250 ENOG4107TDF Formate hydrogenlyase subunit 4 HQN80_RS05255 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) HQN80_RS05260 ENOG4108RG7 formate hydrogenlyase complex iron-sulfur subunit HQN80_RS05265 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit HQN80_RS05270 ENOG4105I6X formate hydrogenlyase maturation HQN80_RS05275 ENOG4108MG9 hydrogenase 3 maturation protease HQN80_RS05285 ENOG4105RVE Uncharacterized protein conserved in bacteria (DUF2136) HQN80_RS05290 ENOG4108Z3N Transcriptional regulator HQN80_RS05295 ENOG4105CS2 ec 3.2.1.21 HQN80_RS05300 ENOG4105C5Y PTS System HQN80_RS05305 ENOG4105DDV Transcriptional regulator (LacI family HQN80_RS05310 ENOG4108RC0 Electron transport protein HQN80_RS05315 ENOG4105C8H hydrogenase maturation protein Hypf HQN80_RS05320 ENOG4108EQM faD-dependent pyridine nucleotide-disulfide oxidoreductase HQN80_RS05325 ENOG4108ESE uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center HQN80_RS05340 ENOG410804X Transcriptional regulator HQN80_RS05345 ENOG4105J92 DNA-binding transcriptional activator GutM HQN80_RS05350 ENOG4107QMF Sorbitol-6-phosphate dehydrogenase HQN80_RS05355 ENOG4105VI0 Pts system, glucitol sorbitol-specific HQN80_RS05360 ENOG4105DZY Pts system, glucitol sorbitol-specific HQN80_RS05365 ENOG410787A Pts system, glucitol sorbitol-specific HQN80_RS05370 ENOG4105CVE Lytic murein transglycosylase HQN80_RS05375 ENOG4107TH8 cina domain protein HQN80_RS05395 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) HQN80_RS05425 ENOG4107VXZ Hydrolase HQN80_RS05430 ENOG4105W39 Membrane HQN80_RS05445 ENOG4105C0R drug resistance transporter emrb qaca subfamily HQN80_RS05450 ENOG4105CW7 secretion protein, HlyD family HQN80_RS05455 ENOG4105NTK Transcriptional repressor Mpra HQN80_RS05460 ENOG4105ZED uncharacterized protein ygaH HQN80_RS05465 ENOG4108UMN azlc family HQN80_RS05475 ENOG4105GIJ Glycine betaine HQN80_RS05480 ENOG4108HQS Glycine betaine HQN80_RS05485 ENOG4108IJ7 Glycine betaine HQN80_RS05490 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HQN80_RS05495 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HQN80_RS05505 ENOG4105WAZ (Glutaredoxin-like protein) NrdH HQN80_RS05510 ENOG4108ZQZ Bacterial protein of unknown function (DUF883) HQN80_RS05515 ENOG4108WMJ Protein of unknown function (DUF2002) HQN80_RS05520 ENOG4108RNS Exports L-alanine (By similarity) HQN80_RS05525 ENOG4108X73 DNA- binding protein HQN80_RS05530 ENOG4108V62 Rhodanese domain protein HQN80_RS05535 ENOG41080HT Transcriptional regulator, arsr family HQN80_RS05540 ENOG4105VPI YqaE family transport protein HQN80_RS05545 ENOG4109066 lysm domain bon superfamily protein HQN80_RS05550 ENOG4108PVQ transcriptional regulator HQN80_RS05555 ENOG4105C85 amino acid HQN80_RS05560 ENOG4108JPW Aminotransferase HQN80_RS05565 ENOG4105C26 Dehydrogenase HQN80_RS05570 ENOG4105D5U fad dependent oxidoreductase HQN80_RS05575 ENOG4105EK3 May be involved in the control of utilization of gamma- aminobutyric acid (By similarity) HQN80_RS05600 ENOG4105DZR Type I site-specific deoxyribonuclease HQN80_RS05605 ENOG41082EK Restriction modification system DNA (Specificity HQN80_RS05610 ENOG4105CVR type I restriction-modification system HQN80_RS05625 ENOG4105FA0 parb-like partition protein HQN80_RS05635 ENOG4105DFP Integrase HQN80_RS05650 ENOG4108Z1B Cyclase dehydrase HQN80_RS05660 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) HQN80_RS05665 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) HQN80_RS05680 ENOG4108JU6 CBS domain protein HQN80_RS05685 ENOG4106KVJ cytochrome C assembly protein HQN80_RS05690 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY HQN80_RS05715 ENOG41090EK ompa motb domain protein HQN80_RS05720 ENOG4108KHX Diguanylate cyclase HQN80_RS05725 ENOG4108WS1 HQN80_RS05730 ENOG4105QP9 Protein of unknown function (DUF2799) HQN80_RS05735 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) HQN80_RS05740 ENOG4105EHE chorismate mutase- prephenate dehydrogenase HQN80_RS05745 ENOG4105CQC Prephenate dehydratase HQN80_RS05755 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA HQN80_RS05760 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane HQN80_RS05765 ENOG4105C34 Pseudouridine synthase HQN80_RS05770 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase HQN80_RS05775 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit HQN80_RS05800 ENOG4105CSH Transporter HQN80_RS05805 ENOG4105T42 (LipO)protein HQN80_RS05810 ENOG4105JIM Phosphatidylserine synthase HQN80_RS05815 ENOG4105CD5 CoA-binding domain protein HQN80_RS05820 ENOG4106IUH DTW domain containing protein HQN80_RS05825 ENOG4105K63 Thioredoxin HQN80_RS05830 ENOG4105EIB trna rrna methyltransferase HQN80_RS05850 ENOG41090KR LysR family transcriptional Regulator HQN80_RS05855 ENOG4105C1J atp-dependent rna helicase HQN80_RS05865 ENOG4108IYU L-aspartate oxidase HQN80_RS05875 ENOG4105EMN RNA polymerase sigma factor HQN80_RS05880 ENOG41069PW sigma-e factor negative regulatory protein HQN80_RS05885 ENOG4105VQK sigma E regulatory protein, MucB RseB HQN80_RS05890 ENOG4105WMJ Positive regulator of sigma E, RseC MucC HQN80_RS05900 ENOG4105C3F Signal peptidase i HQN80_RS05920 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) HQN80_RS05935 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding HQN80_RS05940 ENOG4106G6Q Transcriptional regulator HQN80_RS05945 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB HQN80_RS05950 ENOG4108Z6B deaminase HQN80_RS05965 ENOG4107WP9 Histidine kinase HQN80_RS05970 ENOG4108SKK alpha helix protein HQN80_RS05975 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HQN80_RS05985 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) HQN80_RS05995 ENOG4108NZE NAGC-like transcriptional regulator HQN80_RS06000 ENOG4107HQ7 repeat protein HQN80_RS06005 ENOG4105FCA ABC transporter periplasmic-binding protein YphF HQN80_RS06010 ENOG4108F37 ATP-binding component of a transport system HQN80_RS06015 ENOG4105CNN ABC, transporter HQN80_RS06020 ENOG4105CPQ Dehydrogenase HQN80_RS06025 ENOG4108ZKT aldose 1-epimerase HQN80_RS06030 ENOG4108SB3 DoxX Family HQN80_RS06055 ENOG4105FUY alpha subunit HQN80_RS06060 ENOG4108W5M transcriptional regulator HQN80_RS06065 ENOG4105D8G Major Facilitator superfamily HQN80_RS06070 ENOG4108MN2 Stationary phase inducible protein CsiE HQN80_RS06075 ENOG4107XM9 (LipO)protein HQN80_RS06080 ENOG4105ECY inositol monophosphatase HQN80_RS06100 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins HQN80_RS06120 ENOG4108ZIT Ferredoxin, 2FE-2S HQN80_RS06125 ENOG4105WVQ Fe-S assembly protein IscX HQN80_RS06135 ENOG4105YYA enhanced serine sensitivity protein SseB HQN80_RS06140 ENOG4105KHC sulfurtransferase HQN80_RS06145 ENOG4105DN3 alpha-2-macroglobulin domain protein HQN80_RS06150 ENOG4108JQB penicillin-binding protein 1C HQN80_RS06180 ENOG4105N21 Membrane HQN80_RS06195 ENOG4105VPD cellular component movement HQN80_RS06205 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) HQN80_RS06215 ENOG41066DY Membrane HQN80_RS06220 ENOG4108ZMA Outer membrane lipoprotein HQN80_RS06225 ENOG41062G3 Protein of unknown function (DUF2633) HQN80_RS06235 ENOG4105BZU Histidine kinase HQN80_RS06240 ENOG4105C9X ppx gppa phosphatase HQN80_RS06245 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) HQN80_RS06250 ENOG4108V3E phosphoribosylglycinamide formyltransferase HQN80_RS06265 ENOG4105C2W permease HQN80_RS06270 ENOG4108KZ1 Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity) HQN80_RS06275 ENOG4105K89 arsenate reductase HQN80_RS06280 ENOG4105ERG peptidase m48, ste24p HQN80_RS06285 ENOG4105C02 permease HQN80_RS06290 ENOG4105TMB Formate nitrite transporter HQN80_RS06295 ENOG4108JUA Transcriptional regulator HQN80_RS06300 ENOG4105I6X formate hydrogenlyase maturation HQN80_RS06305 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit HQN80_RS06315 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) HQN80_RS06320 ENOG4108JPZ Monovalent cation H antiporter subunit D HQN80_RS06325 ENOG4107WQX hydrogenase 4 membrane subunit HQN80_RS06335 ENOG4107TDF Formate hydrogenlyase subunit 4 HQN80_RS06345 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) HQN80_RS06350 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen HQN80_RS06355 ENOG4105RH4 Glycine cleavage system transcriptional repressor HQN80_RS06365 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) HQN80_RS06380 ENOG4105M0J Toxic component of a toxin-antitoxin (TA) module. A HQN80_RS06385 ENOG4105CGZ zinc metallopeptidase HQN80_RS06395 ENOG4106KED esterase YpfH HQN80_RS06410 ENOG4105KUZ arsenate reductase HQN80_RS06420 ENOG4105BZS acriflavin resistance protein HQN80_RS06425 ENOG4105BZU Histidine kinase HQN80_RS06430 ENOG4105BZ8 glutamate synthase HQN80_RS06440 ENOG4108PVD exported protein HQN80_RS06445 ENOG4105CV1 Transketolase (EC 2.2.1.1) HQN80_RS06450 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) HQN80_RS06455 ENOG4105C6K Malic enzyme HQN80_RS06460 ENOG4108VJN May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place HQN80_RS06465 ENOG4106S4J ethanolamine utilization protein EutP HQN80_RS06470 ENOG4105NDK ethanolamine utilization protein HQN80_RS06475 ENOG4108PFF ethanolamine utilization cobalamin adenosyltransferase HQN80_RS06485 ENOG4105KNY Microcompartments protein HQN80_RS06490 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml HQN80_RS06495 ENOG4108EKI Dehydrogenase HQN80_RS06500 ENOG4107RWI ethanolamine utilization protein eutJ HQN80_RS06505 ENOG4105C0A alcohol dehydrogenase HQN80_RS06510 ENOG4105ENY Ethanolamine utilization protein eutH HQN80_RS06515 ENOG4105DYY Reactivating factor for ethanolamine ammonia lyase HQN80_RS06520 ENOG4105CPD ethanolamine ammonia-lyase HQN80_RS06530 ENOG4106D67 ethanolamine utilization protein HQN80_RS06535 ENOG4108X49 Ethanolamine utilization protein EutK HQN80_RS06540 ENOG4108K3Z AraC family transcriptional regulator HQN80_RS06550 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase HQN80_RS06560 ENOG4105QZU Inner membrane protein YfeZ HQN80_RS06565 ENOG4105E7K (LipO)protein HQN80_RS06570 ENOG4105EZR dyp-type peroxidase family protein HQN80_RS06575 ENOG4107S1E Beta-lactamase HQN80_RS06580 ENOG4105C5Y PTS System HQN80_RS06595 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr HQN80_RS06600 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein HQN80_RS06605 ENOG4108I5D sulfate abc transporter HQN80_RS06610 ENOG4105ECW sulfate abc transporter HQN80_RS06615 ENOG4108IJ6 ABC transporter HQN80_RS06620 ENOG4105C6T cysteine synthase HQN80_RS06625 ENOG4105M0Y HQN80_RS06635 ENOG4105C5Y PTS System HQN80_RS06640 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) HQN80_RS06650 ENOG4105C6T cysteine synthase HQN80_RS06670 ENOG4105VRT cytoplasmic protein HQN80_RS06675 ENOG4105DHU Bile acid HQN80_RS06680 ENOG4108M0I Transcriptional regulator HQN80_RS06685 ENOG4108NFH Sugar hydrolase HQN80_RS06690 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) HQN80_RS06695 ENOG4105EAA nucleoside HQN80_RS06705 ENOG4105CN8 Transcriptional regulator HQN80_RS06735 ENOG4105GXM Putative transcription regulator (DUF1323) HQN80_RS06740 ENOG4105HZG regulatoR HQN80_RS06755 ENOG4108KMM Diguanylate cyclase HQN80_RS06760 ENOG4105D9N nucleoside HQN80_RS06770 ENOG4109076 Conserved Protein HQN80_RS06785 ENOG4105R6B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) HQN80_RS06790 ENOG410863U PTS System HQN80_RS06800 ENOG4105CN9 Peptidase m42 family protein HQN80_RS06805 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) HQN80_RS06810 ENOG4108CIP transcriptional regulator HQN80_RS06815 ENOG4105DY9 regulatoR HQN80_RS06820 ENOG4108HRK Histidine kinase HQN80_RS06825 ENOG4105CHM Aminotransferase HQN80_RS06835 ENOG4105D1S lipid A biosynthesis HQN80_RS06840 ENOG4105W9M Membrane HQN80_RS06850 ENOG4108V08 YfdX protein HQN80_RS06860 ENOG4105CFN oxalyl-CoA decarboxylase HQN80_RS06865 ENOG4108N2Y auxin Efflux HQN80_RS06885 ENOG4105BZU Histidine kinase HQN80_RS06890 ENOG4108WQH regulatoR HQN80_RS06895 ENOG4105CW7 secretion protein, HlyD family HQN80_RS06900 ENOG4105C0R drug resistance transporter emrb qaca subfamily HQN80_RS06905 ENOG4105BZC d-serine deaminase HQN80_RS06915 ENOG4106NDP Transcriptional regulator HQN80_RS06920 ENOG4108HKT sucrose-6-phosphate hydrolase HQN80_RS06925 ENOG4105D7K pfkb domain protein HQN80_RS06940 ENOG4105S64 Formate nitrite transporter HQN80_RS06945 ENOG410903C (LipO)protein HQN80_RS06955 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation HQN80_RS06960 ENOG4105KZW UPF0381 protein HQN80_RS06975 ENOG4108BY2 phosphohistidine phosphatase HQN80_RS06985 ENOG4106PG1 outer membrane usher protein HQN80_RS06990 ENOG4108FZ9 Chaperone HQN80_RS06995 ENOG4105NEV Fimbrial HQN80_RS07000 ENOG4105UGQ Fimbrial HQN80_RS07005 ENOG4105US4 fimbrial-like protein yfcP HQN80_RS07035 ENOG4105EJ9 Membrane HQN80_RS07040 ENOG4108BPE -transporting atpase HQN80_RS07045 ENOG4105MH2 YfcL protein HQN80_RS07050 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) HQN80_RS07055 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) HQN80_RS07060 ENOG4105F9N Major Facilitator Superfamily HQN80_RS07065 ENOG4106WZ1 flagella biosynthesis regulator HQN80_RS07075 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) HQN80_RS07085 ENOG4105DQR SNARE associated Golgi HQN80_RS07095 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase HQN80_RS07100 ENOG4108S3P Sporulation domain protein HQN80_RS07105 ENOG4105E96 Colicin v production protein HQN80_RS07110 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase HQN80_RS07115 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase HQN80_RS07120 ENOG4105E89 ABC transporter HQN80_RS07125 ENOG4105E89 ABC transporter HQN80_RS07130 ENOG4105DSP amino acid AbC transporter HQN80_RS07135 ENOG4106YG3 ABC transporter HQN80_RS07140 ENOG4108JEH abc transporter atp-binding protein HQN80_RS07145 ENOG4105DNE Transposase HQN80_RS07150 ENOG4105ECP epimerase HQN80_RS07155 ENOG4105KKP D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase HQN80_RS07160 ENOG4105CYM Glutathione S-transferase HQN80_RS07165 ENOG4108SHQ Glutathione S-transferase HQN80_RS07170 ENOG4108RE9 Phosphodiesterase HQN80_RS07175 ENOG4105PTV Nudix Hydrolase HQN80_RS07180 ENOG4105CSX c4-dicarboxylate anaerobic carrier HQN80_RS07185 ENOG4105C6K Malic enzyme HQN80_RS07190 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) HQN80_RS07200 ENOG4105XWI UPF0304 protein HQN80_RS07205 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 HQN80_RS07210 ENOG4107QWE )-transporter HQN80_RS07220 ENOG4105CHM Aminotransferase HQN80_RS07225 ENOG4107NQ8 LysR family Transcriptional regulator HQN80_RS07245 ENOG4105GKE subunit e HQN80_RS07250 ENOG4107QIZ NADH dehydrogenase HQN80_RS07255 ENOG4108IEH NADH dehydrogenase subunit g HQN80_RS07270 ENOG4107UFS subunit j HQN80_RS07280 ENOG4105D65 subunit l HQN80_RS07285 ENOG4105C8S subunit m HQN80_RS07295 ENOG4105GDX Domain of unknown function (DUF1877) HQN80_RS07300 ENOG4107VAM peptidase, m28 HQN80_RS07305 ENOG4105CP2 von willebrand factor, type a HQN80_RS07320 ENOG4107YB6 acetyltransferase, (GNAT) family HQN80_RS07325 ENOG4105TNS Conserved Protein HQN80_RS07330 ENOG4105E4F Isochorismate synthase HQN80_RS07345 ENOG4108IPT Naphthoate synthase HQN80_RS07350 ENOG4105DNI Converts SHCHC to OSB (By similarity) HQN80_RS07355 ENOG4105CEY Amp-dependent synthetase and ligase HQN80_RS07360 ENOG4106GZG polymyxin resistance protein B HQN80_RS07365 ENOG4105U65 Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity) HQN80_RS07375 ENOG4105SA9 Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity) HQN80_RS07410 ENOG4108UII YfaZ family HQN80_RS07415 ENOG4108EWA cinA-like protein HQN80_RS07420 ENOG4107258 Transcriptional regulator HQN80_RS07430 ENOG4105CSP Major Facilitator Superfamily HQN80_RS07445 ENOG4105DNE Transposase HQN80_RS07450 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) HQN80_RS07460 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A HQN80_RS07465 ENOG4105CXY transporter HQN80_RS07470 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase HQN80_RS07490 ENOG4105FQR PH-inducible protein involved in stress response HQN80_RS07495 ENOG4105XPH Ferredoxin HQN80_RS07500 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HQN80_RS07505 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HQN80_RS07510 ENOG4107GHC outer membrane autotransporter HQN80_RS07520 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HQN80_RS07525 ENOG4107FKF Uncharacterized protein conserved in bacteria (DUF2138) HQN80_RS07530 ENOG4108QJJ Protein of unknown function (DUF1175) HQN80_RS07535 ENOG4107S52 alpha-2-macroglobulin domain protein HQN80_RS07540 ENOG41081SK signal peptide protein HQN80_RS07545 ENOG4105EDV vault protein HQN80_RS07550 ENOG4105CHU acetyl-coa acetyltransferase HQN80_RS07555 ENOG4105CRW Short chain fatty acid transporter HQN80_RS07560 ENOG4107QNJ CoA-transferase subunit B HQN80_RS07565 ENOG4107QP7 CoA-transferase subunit A HQN80_RS07570 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HQN80_RS07575 ENOG4105BZU Histidine kinase HQN80_RS07580 ENOG4105BZU Histidine kinase HQN80_RS07585 ENOG41068CG regulatoR HQN80_RS07590 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC HQN80_RS07595 ENOG4105FCK Membrane HQN80_RS07600 ENOG4105CJ2 (LipO)protein HQN80_RS07605 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) HQN80_RS07610 ENOG4105CF1 Alkylated DNA repair protein HQN80_RS07615 ENOG4105IBP Cyclic peptide transporter HQN80_RS07620 ENOG4105DWT malate dehydrogenase (quinone) HQN80_RS07635 ENOG4108ZNS ferredoxin-type protein NapF HQN80_RS07640 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase HQN80_RS07650 ENOG4108BGM Quinol dehydrogenase periplasmic component HQN80_RS07655 ENOG4105GXZ Ferredoxin-type protein NapH HQN80_RS07660 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) HQN80_RS07665 ENOG4105CUW cytochrome C-TYPE protein HQN80_RS07670 ENOG4107EV4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity) HQN80_RS07675 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) HQN80_RS07680 ENOG41060IM Heme exporter protein HQN80_RS07685 ENOG4105X3C heme exporter protein HQN80_RS07695 ENOG4105DA4 cytochrome c-type biogenesis protein HQN80_RS07700 ENOG4107QX9 Thiol disulfide interChange protein HQN80_RS07705 ENOG4105KWW Biogenesis protein HQN80_RS07710 ENOG4105WH1 Two component transcriptional regulator luxr family HQN80_RS07715 ENOG4108MGN ATP-binding component of a transport system HQN80_RS07725 ENOG4105E68 Sulfatase HQN80_RS07745 ENOG4105CFI type iii restriction protein res subunit HQN80_RS07750 ENOG4105I08 Pseudouridine synthase HQN80_RS07755 ENOG4105C2C drug resistance transporter, Bcr CflA HQN80_RS07760 ENOG4105HG6 HQN80_RS07765 ENOG4108JQ5 ABC transporter HQN80_RS07770 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component HQN80_RS07775 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component HQN80_RS07780 ENOG4105E43 Extracellular solute-binding protein, family 5 HQN80_RS07785 ENOG4105CXC rtn protein HQN80_RS07790 ENOG4107TT5 NLP P60 protein HQN80_RS07795 ENOG41076MN Phosphoesterase, PA-phosphatase related HQN80_RS07800 ENOG4105CKI cobalamin synthesis protein HQN80_RS07805 ENOG4105DEI Mannitol dehydrogenase HQN80_RS07815 ENOG4105KRS Proteinase inhibitor HQN80_RS07820 ENOG4105S8Q sugar efflux transporter HQN80_RS07825 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein HQN80_RS07830 ENOG4105DE4 1-phosphofructokinase HQN80_RS07835 ENOG4105DM4 PTS System HQN80_RS07840 ENOG4105DD7 kinase (PfkB family HQN80_RS07845 ENOG4105D53 Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity) HQN80_RS07850 ENOG4105D9N nucleoside HQN80_RS07855 ENOG4108Y4K DNA-binding transcriptional activator HQN80_RS07865 ENOG4105D9N nucleoside HQN80_RS07870 ENOG4105DD7 kinase (PfkB family HQN80_RS07880 ENOG4105HMI Membrane HQN80_RS07885 ENOG4105DUM transcriptional regulator, lysR family HQN80_RS07890 ENOG4108IQI permease HQN80_RS07895 ENOG4105D05 Receptor HQN80_RS07900 ENOG4105C4W S-formylglutathione hydrolase HQN80_RS07910 ENOG4105DHF Membrane HQN80_RS07915 ENOG41060NJ transcriptional regulator HQN80_RS07920 ENOG4105EMA Periplasmic binding protein LacI transcriptional regulator HQN80_RS07925 ENOG4105C2J ABC transporter HQN80_RS07930 ENOG4108HWV )-transporter HQN80_RS07935 ENOG4107SJI Dehydrogenase HQN80_RS07940 ENOG4105BZ8 glutamate synthase HQN80_RS07945 ENOG4105Y9N Membrane HQN80_RS07950 ENOG4107GZ4 SanA protein HQN80_RS07960 ENOG41067MG lrgb family HQN80_RS07970 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) HQN80_RS07980 ENOG4105ETP RND efflux system, outer membrane lipoprotein HQN80_RS07985 ENOG4105H9W Short-chain dehydrogenase reductase Sdr HQN80_RS07990 ENOG4105KHU inner membrane protein YohD HQN80_RS07995 ENOG41069YE inner membrane protein yohC HQN80_RS08000 ENOG41061WM D-Alanyl-D-Alanine HQN80_RS08005 ENOG4105CXG d-lactate dehydrogenase HQN80_RS08010 ENOG4107QK4 glycoside hydrolase, family 3 domain protein HQN80_RS08015 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system HQN80_RS08020 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component HQN80_RS08025 ENOG4108IJ8 ABC transporter HQN80_RS08030 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component HQN80_RS08040 ENOG4108XDN Transcriptional regulator HQN80_RS08045 ENOG4108HRK Histidine kinase HQN80_RS08050 ENOG4108NEV two component transcriptional regulator, LytTR family HQN80_RS08055 ENOG4108W15 Protein of unknown function (DUF1456) HQN80_RS08060 ENOG4108YCW (LipO)protein HQN80_RS08065 ENOG410903U zinc ion binding HQN80_RS08070 ENOG4105DEG Vwa containing coxe family protein HQN80_RS08075 ENOG4105RD5 HQN80_RS08080 ENOG4105KKX ATPase associated with various cellular activities aaa_5 HQN80_RS08095 ENOG4108KDT Molybdate metabolism regulator HQN80_RS08105 ENOG4105D1F ATP-binding protein HQN80_RS08110 ENOG41067AK Protein of unknown function (DUF2574) HQN80_RS08115 ENOG41063W2 Fimbrial protein HQN80_RS08120 ENOG4108MQF Chaperone HQN80_RS08125 ENOG4105CW0 outer membrane usher protein HQN80_RS08130 ENOG410662B Type-1 fimbrial protein HQN80_RS08135 ENOG4108Z1S Influences nickel and cobalt homeostasis. May act by modulating RcnA-mediated export of these ions to avoid excess efflux. Not involved in nickel import and does not bind nickel or cobalt ions directly HQN80_RS08155 ENOG4105DWF phosphomethylpyrimidine kinase HQN80_RS08165 ENOG4105FDP GntR family transcriptional regulator HQN80_RS08170 ENOG4108TFM Kinase, PfkB family HQN80_RS08175 ENOG4108KD5 ADP-ribosylation crystallin J1 HQN80_RS08180 ENOG4105EAA nucleoside HQN80_RS08185 ENOG4105EIE fructose-bisphosphate aldolase HQN80_RS08200 ENOG41082GB PTS system galactitol-specific transporter subunit IIA HQN80_RS08205 ENOG41090UW PTS System HQN80_RS08210 ENOG4105DT3 PTS system, galactitol-specific IIc component HQN80_RS08215 ENOG4107WTH Galactitol-1-phosphate dehydrogenase HQN80_RS08230 ENOG41076Z6 Uncharacterized protein yegR HQN80_RS08235 ENOG4105CFP Peptidase U32 HQN80_RS08245 ENOG4105X54 addiction module antidote protein HQN80_RS08250 ENOG4105KWI UPF0339 protein HQN80_RS08255 ENOG4105E3W Two component transcriptional regulator (Winged helix family HQN80_RS08260 ENOG4105EB3 Histidine kinase HQN80_RS08270 ENOG4105BZS acriflavin resistance protein HQN80_RS08275 ENOG4105BZS acriflavin resistance protein HQN80_RS08300 ENOG4108M24 von Willebrand factor, type A HQN80_RS08305 ENOG4105UM3 Inherit from NOG: serine threonine phosphoprotein phosphatase HQN80_RS08310 ENOG4105ZD5 Uncharacterized protein conserved in bacteria (DUF2314) HQN80_RS08330 ENOG4105R8A Heat shock protein HQN80_RS08335 ENOG4105D03 DNA-3-methyladenine glycosylase II HQN80_RS08340 ENOG4105BZU Histidine kinase HQN80_RS08345 ENOG4105DBI uridine monophosphokinase HQN80_RS08355 ENOG4108GAE asmA family HQN80_RS08360 ENOG4105EE5 Membrane protein terC HQN80_RS08370 ENOG4105DAY polysaccharide export protein HQN80_RS08375 ENOG4105KJF protein tyrosine phosphatase HQN80_RS08380 ENOG4105D75 Capsular exopolysaccharide family HQN80_RS08385 ENOG41090RK glycosyl transferase HQN80_RS08390 ENOG41068PY Colanic acid biosynthesis acetyltransferase wcaB HQN80_RS08395 ENOG4107RXY Glycosyl transferase HQN80_RS08400 ENOG4108NYJ Colanic acid HQN80_RS08405 ENOG4105ECJ Glycosyl Transferase HQN80_RS08410 ENOG4108Z90 colanic acid biosynthesis acetyltransferase wcaF HQN80_RS08415 ENOG4105C0K Gdp-mannose 4,6-dehydratase HQN80_RS08420 ENOG4105C30 Nad-dependent epimerase dehydratase HQN80_RS08425 ENOG4105FGF GDP-mannose mannosyl hydrolase HQN80_RS08430 ENOG4106CD9 glycosyl transferase group 1 HQN80_RS08435 ENOG4105CJT Mannose-1-phosphate guanylyltransferase HQN80_RS08440 ENOG4107QKV phosphomannomutase HQN80_RS08445 ENOG4105D3Q Sugar transferase HQN80_RS08450 ENOG4105PSV Polysaccharide Biosynthesis Protein HQN80_RS08455 ENOG4105C74 pyruvyl transferase HQN80_RS08460 ENOG4107T8Q Glycosyl transferase (Group 1 HQN80_RS08465 ENOG4105G1A colanic acid biosynthesis protein HQN80_RS08470 ENOG4105DMT epimerase dehydratase HQN80_RS08475 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase HQN80_RS08480 ENOG4105C1B dTDP-glucose 4-6-dehydratase HQN80_RS08485 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase HQN80_RS08490 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) HQN80_RS08495 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase HQN80_RS08510 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase HQN80_RS08515 ENOG4108RT7 Glycosyl transferase, family 2 HQN80_RS08540 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) HQN80_RS08550 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase HQN80_RS08555 ENOG4105C1B dTDP-glucose 4-6-dehydratase HQN80_RS08560 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase HQN80_RS08565 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) HQN80_RS08570 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase HQN80_RS08585 ENOG4107SJB teichoic acid biosynthesis HQN80_RS08605 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) HQN80_RS08625 ENOG4105F9F transposase HQN80_RS08635 ENOG4108KPN Confers a modal distribution of chain length on the O- antigen component of lipopolysaccharide (LPS). Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules, with a modal value of 13 (in strain O111 M92) and of 17 (in strain K12) HQN80_RS08655 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) HQN80_RS08660 ENOG4105ECC imidazole-glycerol-phosphate dehydratase HQN80_RS08665 ENOG4105CIH Imidazole acetol-phosphate transaminase HQN80_RS08670 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) HQN80_RS08685 ENOG4105VTW prevent-host-death family HQN80_RS08690 ENOG4105KRQ Addiction module toxin, Txe YoeB family HQN80_RS08695 ENOG4107SRH Nad-dependent epimerase dehydratase HQN80_RS08700 ENOG4105EQ1 Transcriptional regulator HQN80_RS08710 ENOG4105CUB amino acid HQN80_RS08715 ENOG4105CUC YeeE YedE family protein HQN80_RS08725 ENOG4105CJB Exodeoxyribonuclease I HQN80_RS08730 ENOG4105DZ1 carboxypeptidase HQN80_RS08740 ENOG4105DR8 Membrane HQN80_RS08780 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles HQN80_RS08790 ENOG4108YGG dna repair protein HQN80_RS08795 ENOG4105MFG Antirestriction protein HQN80_RS08805 ENOG4105F5W AtP-binding protein HQN80_RS08810 ENOG4105D70 Integrase catalytic subunit HQN80_RS08830 ENOG4108PZQ Inner membrane protein YeeR HQN80_RS08835 ENOG4105F4K antigen 43 HQN80_RS08845 ENOG4108P8R HQN80_RS08895 ENOG4105F9F transposase HQN80_RS08910 ENOG4108YZT Adenosylcobinamide kinase HQN80_RS08915 ENOG4108UHF Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity) HQN80_RS08920 ENOG4105CUP Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity) HQN80_RS08925 ENOG4108PXI ErfK YbiS YcfS YnhG HQN80_RS08935 ENOG4106P55 Transcriptional regulator HQN80_RS08940 ENOG4107R11 Transcriptional regulator HQN80_RS08950 ENOG4105UQX Mate efflux family protein HQN80_RS08960 ENOG4105CDY transcriptional regulatory protein HQN80_RS08965 ENOG4105FYV Amp nucleosidase HQN80_RS08970 ENOG4105CSH Transporter HQN80_RS08980 ENOG4105TNG K13735 adhesin invasin HQN80_RS09000 ENOG4108VKM cytochrome b561 HQN80_RS09005 ENOG4108MEK Metal-binding protein YodA HQN80_RS09020 ENOG4105VT2 5-hydroxyisourate hydrolase HQN80_RS09025 ENOG4105CK6 Two component transcriptional regulator (Winged helix family HQN80_RS09030 ENOG4107ZY3 Histidine kinase HQN80_RS09040 ENOG4105ZIT Porin Gram-negative type HQN80_RS09045 ENOG4105Y0K Inner membrane protein YedR HQN80_RS09050 ENOG4105EST Metal Dependent Phosphohydrolase HQN80_RS09055 ENOG4105DVF Cytosine-specific methyltransferase HQN80_RS09060 ENOG41090BB DNA mismatch endonuclease (vsr) HQN80_RS09065 ENOG4105FDR Membrane HQN80_RS09070 ENOG4105CKW Inner membrane protein yedI HQN80_RS09075 ENOG4105VNZ cytoplasmic protein HQN80_RS09090 ENOG4105YX3 cellular response to acidity HQN80_RS09100 ENOG4107TKS colanic acid capsular biosynthesis activation protein A HQN80_RS09105 ENOG4105D19 Role in flagellar biosynthesis (By similarity) HQN80_RS09115 ENOG4105CN7 Flagellar biosynthetic protein FliP HQN80_RS09120 ENOG4105K0P flagellar biosynthesis protein HQN80_RS09125 ENOG4105DD5 Flagellar motor switch protein HQN80_RS09130 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) HQN80_RS09135 ENOG4107ZI8 flagellar basal body-associated protein flil HQN80_RS09140 ENOG4105WF4 Flagellar hook-length control protein HQN80_RS09145 ENOG4105GSA Flagellar export protein flij HQN80_RS09150 ENOG4108JIR Flagellum-specific ATP synthase HQN80_RS09155 ENOG41090PJ Flagellar assembly protein HQN80_RS09160 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) HQN80_RS09165 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) HQN80_RS09180 ENOG4108V1U phospholipid-binding protein HQN80_RS09185 ENOG4108UQN AraC family transcriptional regulator HQN80_RS09195 ENOG4105D7V transposase HQN80_RS09200 ENOG4108RAV Conserved protein HQN80_RS09210 ENOG41066VF YeeE YedE family protein HQN80_RS09215 ENOG4108W9D (LipO)protein HQN80_RS09220 ENOG4105E5K Alpha-amylase HQN80_RS09230 ENOG4105MQ3 flagellar protein FliS HQN80_RS09235 ENOG4105DTS flagellar hook-associated HQN80_RS09240 ENOG4105I03 Flagellin HQN80_RS09245 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HQN80_RS09250 ENOG4108M9K flagella biosynthesis protein FliZ HQN80_RS09255 ENOG4105EAB amino acid AbC transporter HQN80_RS09260 ENOG4105K6H D-cysteine desulfhydrase HQN80_RS09265 ENOG4105E5Q amino acid AbC transporter HQN80_RS09270 ENOG4105CDA abc transporter atp-binding protein HQN80_RS09275 ENOG4105VJY transcriptional regulator HQN80_RS09280 ENOG4105XVG cytoplasmic protein HQN80_RS09290 ENOG4105WH1 Two component transcriptional regulator luxr family HQN80_RS09320 ENOG4106RHG Yeca family HQN80_RS09325 ENOG4105E0U tyrosine-specific transport protein HQN80_RS09330 ENOG4105VVZ metal-binding protein HQN80_RS09335 ENOG41090A1 ferritin HQN80_RS09340 ENOG4105P23 (LipO)protein HQN80_RS09350 ENOG4105N4N Protein of unknown function (DUF2766) HQN80_RS09355 ENOG4108UEC Ferritin-like protein HQN80_RS09360 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator HQN80_RS09365 ENOG4105C2J ABC transporter HQN80_RS09370 ENOG4105CNN ABC, transporter HQN80_RS09375 ENOG4108K4C ec 3.1.3.12 HQN80_RS09385 ENOG4108VA4 Universal stress protein HQN80_RS09395 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region HQN80_RS09400 ENOG4107RD7 Flagellar Motor Protein, MotA HQN80_RS09405 ENOG4105ER2 Ompa motb domain protein HQN80_RS09410 ENOG4105CBS Chea signal transduction histidine kinase HQN80_RS09415 ENOG4108V3W Chemotaxis protein, CheW HQN80_RS09420 ENOG4105C8Q Methyl-accepting chemotaxis HQN80_RS09425 ENOG4105C8Q Methyl-accepting chemotaxis HQN80_RS09430 ENOG4105BZU Histidine kinase HQN80_RS09440 ENOG4108VYJ response regulator receiver protein HQN80_RS09445 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) HQN80_RS09450 ENOG4105D00 flagellar biosynthetic protein flhB HQN80_RS09455 ENOG4105D7B Flagellar biosynthesis protein flha HQN80_RS09460 ENOG4105W13 flagellar protein HQN80_RS09475 ENOG4106ZCM YecM protein HQN80_RS09485 ENOG4105CUW cytochrome C-TYPE protein HQN80_RS09490 ENOG4108J2R molybdopterin oxidoreductase HQN80_RS09505 ENOG4105WJG Glutathione HQN80_RS09510 ENOG41081XQ Conserved Protein HQN80_RS09570 ENOG4107TII Recombinase HQN80_RS09575 ENOG41081XQ Conserved Protein HQN80_RS09580 ENOG4105D3W isochorismatase HQN80_RS09590 ENOG4108TIT dATP pyrophosphohydrolase HQN80_RS09595 ENOG4105CDY transcriptional regulatory protein HQN80_RS09605 ENOG4107S01 Repressor protein MetJ HQN80_RS09625 ENOG4105FAV ABC, transporter HQN80_RS09635 ENOG4105NXV High-affinity zinc uptake system protein HQN80_RS09640 ENOG4105DR5 peptidase HQN80_RS09645 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase HQN80_RS09650 ENOG4105CA9 Pyruvate kinase HQN80_RS09655 ENOG4106KNT transcriptional regulator HQN80_RS09660 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase HQN80_RS09665 ENOG4105C01 Dihydroxy-acid dehydratase HQN80_RS09670 ENOG4108UHU Aldolase HQN80_RS09680 ENOG4105X2V dna damage-inducible protein HQN80_RS09690 ENOG4108Q2J Inner membrane protein YebE HQN80_RS09695 ENOG4105CUG Oligopeptidase b HQN80_RS09700 ENOG4105UMD exodeoxyribonuclease X HQN80_RS09705 ENOG4108YGA nitrilase cyanide hydratase and apolipoprotein n-acyltransferase HQN80_RS09710 ENOG4105MPK DNA polymerase III subunit theta HQN80_RS09715 ENOG4105FXM Copper resistance protein HQN80_RS09720 ENOG4108PNC copper resistance HQN80_RS09725 ENOG4105NKT exported protein HQN80_RS09730 ENOG4108R1E Serine threonine protein phosphatase 1 HQN80_RS09735 ENOG4105UVW uncharacterized protein yebW HQN80_RS09740 ENOG4105WT8 Protein of unknown function (DUF1480) HQN80_RS09750 ENOG4105DY2 Paraquat-inducible protein b HQN80_RS09755 ENOG4105H2K paraquat-inducible protein a HQN80_RS09760 ENOG4108ZGC gaf domain protein HQN80_RS09770 ENOG4105CN1 protease HQN80_RS09780 ENOG4105C0R drug resistance transporter emrb qaca subfamily HQN80_RS09785 ENOG4105J4Q Transcriptional regulator HQN80_RS09790 ENOG4105TIK HQN80_RS09800 ENOG4105Q3Y exported protein HQN80_RS09815 ENOG4105DHI Methyltransferase HQN80_RS09830 ENOG4105F3R pts system mannose fructose sorbose family iid HQN80_RS09835 ENOG4105ETZ PTS System HQN80_RS09840 ENOG4105DAS pts system HQN80_RS09845 ENOG4105EE5 Membrane protein terC HQN80_RS09850 ENOG4107XTP (EAL) domain protein HQN80_RS09855 ENOG4105EJQ L-serine dehydratase HQN80_RS09865 ENOG4105CRQ synthase (Component I) HQN80_RS09875 ENOG4105V2F Uncharacterized protein yoac HQN80_RS09880 ENOG4105M4H endoribonuclease L-psp HQN80_RS09885 ENOG4105DVT helicase HQN80_RS09890 ENOG41072GX Peptidase M22 Glycoprotease HQN80_RS09895 ENOG4105Y4Z Outer Membrane Lipoprotein HQN80_RS09900 ENOG4105CEY Amp-dependent synthetase and ligase HQN80_RS09905 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) HQN80_RS09910 ENOG4105E3J oxidoreductase HQN80_RS09915 ENOG4105DVW rieske (2Fe-2S) HQN80_RS09920 ENOG4105C94 Transporter HQN80_RS09925 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) HQN80_RS09940 ENOG4108YS1 cytoplasmic protein HQN80_RS09945 ENOG4105YP6 Domain of unknown function (DUF1869) HQN80_RS09950 ENOG4105Y3U Transglycosylase-associated protein HQN80_RS09960 ENOG4106G4W HQN80_RS09965 ENOG410620I Diguanylate cyclase HQN80_RS09970 ENOG4105UCG Domain of unknown function (DUF333) HQN80_RS09975 ENOG4105K78 MarR family Transcriptional regulator HQN80_RS09980 ENOG4105DJ2 Major Facilitator Superfamily HQN80_RS09985 ENOG4105R1U AraC Family Transcriptional Regulator HQN80_RS10000 ENOG4108KXH Ybak prolyl-tRNA synthetase associated HQN80_RS10005 ENOG4108KHP Diguanylate cyclase HQN80_RS10010 ENOG4106KTS Inner membrane protein yeaI HQN80_RS10020 ENOG4105CYN Serine protein kinase HQN80_RS10025 ENOG4105GNX MltA-interacting MipA family protein HQN80_RS10030 ENOG4105CV8 reductase HQN80_RS10035 ENOG4105DSB aldose 1-epimerase HQN80_RS10040 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase HQN80_RS10050 ENOG4105VUT cytoplasmic protein HQN80_RS10055 ENOG4108RWI nicotinamidase HQN80_RS10060 ENOG4105HDK L-asparaginase HQN80_RS10065 ENOG4105D07 Signal peptide peptidase, SppA HQN80_RS10070 ENOG41069NU Nitroreductase HQN80_RS10080 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) HQN80_RS10085 ENOG41065FB inner membrane protein ynji HQN80_RS10090 ENOG4105D82 Glutamate dehydrogenase HQN80_RS10095 ENOG4105MTM Protein of unknown function (DUF1496) HQN80_RS10100 ENOG4105M6F mutator MutT protein HQN80_RS10105 ENOG4108T9J Cdp-alcohol phosphatidyltransferase HQN80_RS10110 ENOG4107RM6 sulfurtransferase HQN80_RS10115 ENOG4108VGW abc transporter atp-binding protein HQN80_RS10120 ENOG4105CXZ ABC transporter, permease HQN80_RS10125 ENOG4105VNH ABC transporter solute-binding protein HQN80_RS10130 ENOG4107ZN8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) HQN80_RS10135 ENOG4108N5C SNARE associated Golgi protein-related protein HQN80_RS10140 ENOG4108KCW iron-sulfur cluster binding HQN80_RS10145 ENOG4108RSN SNARE associated Golgi HQN80_RS10150 ENOG4105CGK Exodeoxyribonuclease III HQN80_RS10180 ENOG4108SPG Periplasmic Protein HQN80_RS10190 ENOG4105DKD Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity) HQN80_RS10200 ENOG4105KKI DNA-binding transcriptional activator OsmE HQN80_RS10205 ENOG4105VZJ PTS System HQN80_RS10210 ENOG4105CK1 PTS System HQN80_RS10215 ENOG4105VCP PTS System HQN80_RS10220 ENOG4105EZV Transcriptional regulator HQN80_RS10225 ENOG4105F8D glycoside hydrolase family 4 HQN80_RS10235 ENOG4105CH6 catalase HQN80_RS10250 ENOG4108ETY sodium dicarboxylate symporter HQN80_RS10255 ENOG4107K5X Membrane-bound metal-dependent hydrolase HQN80_RS10260 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 HQN80_RS10265 ENOG4107PN8 YfeABCD locus regulator HQN80_RS10275 ENOG4105P10 Uncharacterized protein ydiZ HQN80_RS10280 ENOG4105DE4 1-phosphofructokinase HQN80_RS10285 ENOG4108NE3 Salt-induced outer membrane protein HQN80_RS10305 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) HQN80_RS10310 ENOG41082NX 50s ribosomal protein l35 HQN80_RS10345 ENOG4108V06 Glutathione peroxidase HQN80_RS10355 ENOG4108QBX (LipO)protein HQN80_RS10360 ENOG4108TC0 Diguanylate phosphodiesterase HQN80_RS10375 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) HQN80_RS10385 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) HQN80_RS10390 ENOG4105CEY Amp-dependent synthetase and ligase HQN80_RS10395 ENOG41090P5 ferredoxin-like protein HQN80_RS10400 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase HQN80_RS10405 ENOG4105C10 Electron transfer flavoprotein HQN80_RS10410 ENOG4105CV7 Electron transfer flavoprotein HQN80_RS10415 ENOG4105W4W Transcriptional regulator HQN80_RS10420 ENOG4105C1G acyl-Coa dehydrogenase HQN80_RS10425 ENOG4108IIG CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) HQN80_RS10440 ENOG4105EMV Major Facilitator HQN80_RS10445 ENOG4105EMV Major Facilitator HQN80_RS10450 ENOG4105SUA Ydil protein HQN80_RS10460 ENOG4105IPI Membrane HQN80_RS10465 ENOG4105CQB FAD linked oxidase domain protein HQN80_RS10470 ENOG4105KA0 thioesterase Superfamily protein HQN80_RS10475 ENOG410671Z uncharacterized protein ydiH HQN80_RS10480 ENOG4108Z4V iron-sulfur cluster assembly HQN80_RS10485 ENOG4105DIW FeS assembly protein SUFB HQN80_RS10490 ENOG4105C3K feS assembly ATPase SufC HQN80_RS10495 ENOG4105JRK feS assembly protein SufD HQN80_RS10510 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein HQN80_RS10515 ENOG4105KMX major outer membrane lipoprotein HQN80_RS10520 ENOG4105CA9 Pyruvate kinase HQN80_RS10525 ENOG4105RFR Protein of unknown function (DUF2767) HQN80_RS10530 ENOG4108PU5 4fe-4S ferredoxin, iron-sulfur binding domain protein HQN80_RS10535 ENOG4105WE2 aldehyde ferredoxin oxidoreductase HQN80_RS10540 ENOG4105JVW HQN80_RS10545 ENOG4108393 oxidoreductase Fe-S subunit HQN80_RS10550 ENOG4108NWD Cytochrome HQN80_RS10555 ENOG4108Y7C Conserved Protein HQN80_RS10560 ENOG4108KTU conserved protein with FAD NAD(P)-binding domain HQN80_RS10565 ENOG4105N0V mono-oxygenase ydhR HQN80_RS10590 ENOG4108R6K riboflavin synthase, subunit alpha HQN80_RS10595 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase HQN80_RS10600 ENOG4105CZQ inner membrane transport protein YdhC HQN80_RS10605 ENOG4105F52 Transcriptional regulator HQN80_RS10620 ENOG4105F27 Major Facilitator HQN80_RS10625 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) HQN80_RS10630 ENOG4105K4H Nlp p60 protein HQN80_RS10635 ENOG4105M2J Glutaredoxin HQN80_RS10640 ENOG4107QRT dEAD DEAH box helicase HQN80_RS10650 ENOG4108UYE Lactoylglutathione lyase HQN80_RS10655 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase HQN80_RS10660 ENOG4108WUH Transcriptional regulator, TetR family HQN80_RS10665 ENOG4105XZD Fe-S protein HQN80_RS10670 ENOG4107RGM aldo keto reductase HQN80_RS10675 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) HQN80_RS10680 ENOG4105DSW Fusaric acid resistance protein HQN80_RS10685 ENOG4105Y49 secretion protein, HlyD family HQN80_RS10700 ENOG4108XTF Outer Membrane Lipoprotein HQN80_RS10710 ENOG410642K Lysozyme inhibitor HQN80_RS10725 ENOG4107XGF functions in a salvage pathway. Uses pyridoxamine (By similarity) HQN80_RS10730 ENOG4108K3A Glutathione S-transferase HQN80_RS10735 ENOG4105DUX Transporter HQN80_RS10740 ENOG4105CSM endonuclease III HQN80_RS10750 ENOG4108UQQ Electron transport complex HQN80_RS10775 ENOG4105M9B inner membrane protein ydgK HQN80_RS10780 ENOG4105QZ5 OriC-binding nucleoid-associated protein HQN80_RS10785 ENOG4106C6R beta-lactam resistance protein HQN80_RS10790 ENOG4105D9R oxidoreductase HQN80_RS10800 ENOG4105C87 Aminotransferase class I and II HQN80_RS10805 ENOG4105CI1 PTS System HQN80_RS10810 ENOG4107P2S Transcriptional regulator HQN80_RS10815 ENOG4107ZQV short-chain dehydrogenase reductase HQN80_RS10820 ENOG4105XEA Tetr family transcriptional regulator HQN80_RS10825 ENOG4105CNT hydrolase family 2 HQN80_RS10830 ENOG4105CT4 transporter HQN80_RS10835 ENOG4108QNI outer membrane porin protein HQN80_RS10840 ENOG4106J39 exported protein HQN80_RS10845 ENOG4105EIP mannose-6-phosphate isomerase HQN80_RS10850 ENOG4107GFK fumarate HQN80_RS10855 ENOG4105C9Q fumarate hydratase class II HQN80_RS10865 ENOG4105JJR Histidine kinase HQN80_RS10870 ENOG4107EXC regulatoR HQN80_RS10875 ENOG4105RA2 Membrane HQN80_RS10885 ENOG4105D5Q Arginine ornithine antiporter HQN80_RS10890 ENOG4105C5D exported protein HQN80_RS10895 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) HQN80_RS10900 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) HQN80_RS10905 ENOG4105DSF transport protein HQN80_RS10920 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap HQN80_RS10935 ENOG4105D94 Major Facilitator Superfamily HQN80_RS10940 ENOG4106NZI LysR family Transcriptional regulator HQN80_RS10945 ENOG4105DAG ROK family HQN80_RS10950 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) HQN80_RS10960 ENOG4108NEM leader-binding protein dmsD HQN80_RS10965 ENOG4107KGK dmso reductase anchor subunit HQN80_RS10970 ENOG4105QAX Iron-sulfur HQN80_RS10975 ENOG4105C3J Cysteine desulfurase HQN80_RS10980 ENOG4107QY8 reductase HQN80_RS10985 ENOG4105KBG Protein of unknown function (DUF1161) HQN80_RS10990 ENOG4105D69 UPF0257 lipoprotein ynfC HQN80_RS10995 ENOG4108MK9 spermidine N(1)-acetyltransferase HQN80_RS11010 ENOG4105CXK mandelate racemase muconate lactonizing HQN80_RS11015 ENOG4105CPQ Dehydrogenase HQN80_RS11025 ENOG4107R08 Integrase HQN80_RS11040 ENOG4106G8A Qin prophage HQN80_RS11105 ENOG4108MXB Protein of unknown function (DUF968) HQN80_RS11110 ENOG4105KSK (crossover) junction endodeoxyribonuclease HQN80_RS11115 ENOG4105HGD Antitermination protein HQN80_RS11170 ENOG4105DEI Mannitol dehydrogenase HQN80_RS11175 ENOG41061EV selenium-binding protein YdfZ HQN80_RS11180 ENOG4107XBN GntR Family Transcriptional Regulator HQN80_RS11185 ENOG4105EMU Dehydrogenase HQN80_RS11190 ENOG4105DGW oligopeptidase A HQN80_RS11195 ENOG4108WTK competence damage-inducible protein HQN80_RS11200 ENOG4108YDI single-species biofilm formation on inanimate substrate HQN80_RS11205 ENOG4105FSR swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria HQN80_RS11215 ENOG4105E5W Transporter HQN80_RS11220 ENOG4108594 Permease of the drug metabolite transporter HQN80_RS11225 ENOG4105FDP GntR family transcriptional regulator HQN80_RS11235 ENOG4105CK1 PTS System HQN80_RS11240 ENOG4105VCP PTS System HQN80_RS11250 ENOG4105CS2 ec 3.2.1.21 HQN80_RS11255 ENOG4106DNR multiple antibiotic resistance protein HQN80_RS11260 ENOG4108XW0 May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF HQN80_RS11265 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes HQN80_RS11285 ENOG4105EGI Transcriptional regulator HQN80_RS11290 ENOG4105C26 Dehydrogenase HQN80_RS11295 ENOG4105CSV Glutaminase HQN80_RS11300 ENOG4105M0C cytoplasmic protein HQN80_RS11305 ENOG4105BZU Histidine kinase HQN80_RS11315 ENOG4105FFC UPF0187 protein HQN80_RS11320 ENOG4107R6G Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity) HQN80_RS11325 ENOG4105K34 Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the cleavage of phosphorylated 4,5- dihydroxy-2,3-pentanedione (P-DPD) to 2-phosphoglycolic acid (PG) and another three-carbon compound HQN80_RS11350 ENOG4105C2J ABC transporter HQN80_RS11370 ENOG41061P8 Persistence to inhibition of murein or DNA biosynthesis regulatory protein HQN80_RS11375 ENOG4105CAF HipA N-terminal domain protein HQN80_RS11385 ENOG4108RQP Major type 1 subunit fimbrin HQN80_RS11395 ENOG4105CW0 outer membrane usher protein HQN80_RS11400 ENOG4108WDE Fimbrial protein HQN80_RS11405 ENOG4106318 fimbrial-like protein YdeR HQN80_RS11410 ENOG4106PIH fimbrial-like protein ydeQ HQN80_RS11415 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit HQN80_RS11465 ENOG4105CQ0 ABC transporter HQN80_RS11470 ENOG4105PE1 Receptor HQN80_RS11475 ENOG4107RAN Peptidase, M16 HQN80_RS11480 ENOG4105CVK Glutamate decarboxylase HQN80_RS11485 ENOG4105E5D amino acid HQN80_RS11490 ENOG4105F32 YngK protein HQN80_RS11500 ENOG4105BZU Histidine kinase HQN80_RS11505 ENOG4108UQS dipeptidase HQN80_RS11510 ENOG4105DEF Extracellular solute-binding protein, family 5 HQN80_RS11515 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HQN80_RS11520 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HQN80_RS11525 ENOG4105C3U ABC transporter HQN80_RS11530 ENOG4107H6U ABC transporter HQN80_RS11535 ENOG4108Z9K Osmotically inducible protein HQN80_RS11540 ENOG4105TPS biofilm-dependent modulation protein HQN80_RS11545 ENOG4107AV5 Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein HQN80_RS11555 ENOG4105DQ4 alcohol dehydrogenase HQN80_RS11560 ENOG41084S7 Plasmid maintenance system antidote protein HQN80_RS11565 ENOG4108MG3 formate dehydrogenase HQN80_RS11570 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HQN80_RS11580 ENOG4105RPH Inner membrane protein YddG HQN80_RS11595 ENOG4107QND Nitrite extrusion protein HQN80_RS11600 ENOG4105CRU nitrate reductase, alpha subunit HQN80_RS11605 ENOG4108IUE nitrate reductase beta subunit HQN80_RS11610 ENOG4108NZN Respiratory nitrate reductase 2 delta chain HQN80_RS11615 ENOG4105D0D Nitrate reductase 2, gamma subunit HQN80_RS11620 ENOG4105JAB phenazine biosynthesis protein, phzf family HQN80_RS11625 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase HQN80_RS11630 ENOG4108MEJ flavin reductase domain protein HQN80_RS11660 ENOG4105CNA YD repeat protein HQN80_RS11665 ENOG4105CS6 Rhs element vgr protein HQN80_RS11675 ENOG4108N27 Glutathione S-transferase HQN80_RS11680 ENOG4105C85 amino acid HQN80_RS11685 ENOG4108NS2 receptor HQN80_RS11690 ENOG4105CHB tonB-dependent Receptor HQN80_RS11695 ENOG4108WYP Transcriptional regulator HQN80_RS11700 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein HQN80_RS11705 ENOG4108Z7F N-acetyltransferase HQN80_RS11710 ENOG4108T9Y Inner membrane protein ydcZ HQN80_RS11715 ENOG4105R71 cytoplasmic protein HQN80_RS11720 ENOG410654E Membrane HQN80_RS11735 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component HQN80_RS11740 ENOG4105D81 ABC transporter, permease HQN80_RS11745 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) HQN80_RS11750 ENOG4107TYH extracellular solute-binding protein family 1 HQN80_RS11755 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family HQN80_RS11760 ENOG4105PF0 Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin HQN80_RS11770 ENOG4105RR0 Protein of unknown function (DUF2554) HQN80_RS11775 ENOG4105CFP Peptidase U32 HQN80_RS11780 ENOG4108JCI Transcriptional regulator HQN80_RS11785 ENOG4105DKK Benzoate HQN80_RS11790 ENOG4105D7V transposase HQN80_RS11800 ENOG4108KKZ (LipO)protein HQN80_RS11805 ENOG41088CC tellurite resistance protein tehB HQN80_RS11810 ENOG4108NKP c4-dicarboxylate transporter malic acid transport protein HQN80_RS11815 ENOG4107WE3 acetyltransferase YdcK HQN80_RS11820 ENOG4108Z9I -acetyltransferase HQN80_RS11825 ENOG4105Z2P Protein of unknown function (DUF465) HQN80_RS11835 ENOG4105E32 cytoplasmic protein HQN80_RS11840 ENOG4105DDW LysR family Transcriptional regulator HQN80_RS11845 ENOG4105C8Q Methyl-accepting chemotaxis HQN80_RS11850 ENOG4107NK6 Hok/gef family HQN80_RS11855 ENOG4105UPP uncharacterized protein ydcA HQN80_RS11860 ENOG4105CPW cytochrome b561 HQN80_RS11865 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase HQN80_RS11870 ENOG4105C26 Dehydrogenase HQN80_RS11875 ENOG4107DB1 DUF218 domain HQN80_RS11880 ENOG4105CQ7 ATP-dependent helicase HQN80_RS11890 ENOG41077RS Phosphatase HQN80_RS11895 ENOG4105E8V Alpha Beta Hydrolase Fold protein HQN80_RS11900 ENOG4108HPI phosphatidate Cytidylyltransferase HQN80_RS11905 ENOG4108UMZ Cdp-alcohol phosphatidyltransferase HQN80_RS11915 ENOG4107S5I aldo keto reductase HQN80_RS11920 ENOG4108Z0R Transferase HQN80_RS11925 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein HQN80_RS11930 ENOG4105DZS Phenylacetate-CoA ligase HQN80_RS11935 ENOG4105CHU acetyl-coa acetyltransferase HQN80_RS11940 ENOG4108ZJI phenylacetic acid degradation protein HQN80_RS11945 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase HQN80_RS11950 ENOG4108UKI Enoyl-CoA hydratase HQN80_RS11955 ENOG4105E39 Enoyl-CoA hydratase HQN80_RS11960 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) HQN80_RS11965 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit HQN80_RS11970 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit HQN80_RS11975 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit HQN80_RS11980 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit HQN80_RS11985 ENOG4105DXM phenylacetic acid degradation protein HQN80_RS11990 ENOG4105F11 amine oxidase HQN80_RS11995 ENOG4105C26 Dehydrogenase HQN80_RS12000 ENOG4108WFR AraC Family Transcriptional Regulator HQN80_RS12005 ENOG4105WXT Conserved Protein HQN80_RS12010 ENOG410689M (LipO)protein HQN80_RS12015 ENOG4107H52 Dicarboxylate transport HQN80_RS12020 ENOG4105C5I Dehydrogenase HQN80_RS12025 ENOG41090X5 Heat shock protein hslJ HQN80_RS12030 ENOG4105IKK cytoplasmic protein HQN80_RS12035 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) HQN80_RS12040 ENOG4105FCK Membrane HQN80_RS12045 ENOG4108RW8 Universal stress protein F HQN80_RS12055 ENOG4105C1J atp-dependent rna helicase HQN80_RS12065 ENOG4105BZU Histidine kinase HQN80_RS12070 ENOG4108DG9 Smr protein MutS2 HQN80_RS12075 ENOG4106KR7 LysR family Transcriptional regulator HQN80_RS12080 ENOG4105CH2 amidohydrolase HQN80_RS12085 ENOG4107RT5 aminobenzoyl-glutamate utilization protein B HQN80_RS12090 ENOG4105CFC Transporter HQN80_RS12095 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) HQN80_RS12100 ENOG4105DS0 Transcriptional regulator, Crp Fnr family HQN80_RS12105 ENOG4105Q9Y Universal stress protein HQN80_RS12110 ENOG4105S5I Membrane HQN80_RS12115 ENOG4105D64 Mechanosensitive ion channel HQN80_RS12120 ENOG4107QSI ABC, transporter HQN80_RS12125 ENOG4105EQ2 LysR family Transcriptional regulator HQN80_RS12130 ENOG4105ENX hydrolase HQN80_RS12145 ENOG4105KXI murein peptide amidase A HQN80_RS12150 ENOG4107S8C mandelate racemase muconate lactonizing HQN80_RS12155 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) HQN80_RS12160 ENOG4108JU8 Transcriptional regulator HQN80_RS12170 ENOG4105CM6 amino acid regulated cytosolic protein HQN80_RS12175 ENOG4105FKQ transcriptional regulator HQN80_RS12180 ENOG4107EFV Outer membrane protein G HQN80_RS12185 ENOG4108IJ9 (ABC) transporter HQN80_RS12190 ENOG4107URF beta-phospho-glucomutase HQN80_RS12195 ENOG4105C71 hydrolase family 65, central catalytic HQN80_RS12200 ENOG4105CK5 oxidoreductase HQN80_RS12205 ENOG4107TYA transient receptor potential locus HQN80_RS12210 ENOG4107RRD Dehydrogenase HQN80_RS12215 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component HQN80_RS12220 ENOG4105HS6 binding-protein-dependent transport systems inner membrane Component HQN80_RS12225 ENOG4105WEM extracellular solute-binding protein HQN80_RS12230 ENOG4107QW3 Sucrose phosphorylase HQN80_RS12235 ENOG4105K8Z Phage shock protein HQN80_RS12240 ENOG4105NNG Peripheral inner membrane phage-shock protein HQN80_RS12245 ENOG4105FM1 phage shock protein C HQN80_RS12250 ENOG4105YYT phage shock protein B HQN80_RS12255 ENOG41087YS Phage shock protein A HQN80_RS12260 ENOG4105E51 psp operon transcriptional activator HQN80_RS12265 ENOG4108JPW Aminotransferase HQN80_RS12270 ENOG4105CJP fad dependent oxidoreductase HQN80_RS12275 ENOG4105C26 Dehydrogenase HQN80_RS12280 ENOG4107VRI Transcriptional regulator HQN80_RS12285 ENOG4108Z86 Glutamine amidotransferase HQN80_RS12290 ENOG4105CFQ glutamine synthetase HQN80_RS12300 ENOG4105CUB amino acid HQN80_RS12305 ENOG4105N0E Protein of unknown function (DUF2543) HQN80_RS12310 ENOG4108HIY periplasmic HQN80_RS12315 ENOG4108I5W peptide transport system, permease protein HQN80_RS12320 ENOG4108EU3 peptide transport system, permease HQN80_RS12325 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein HQN80_RS12330 ENOG4108JQ2 peptide transport system atp-binding protein HQN80_RS12335 ENOG4105WDY DNA (cytosine-5-)-methyltransferase HQN80_RS12340 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH HQN80_RS12345 ENOG4105Q4T oxidoreductase HQN80_RS12360 ENOG4105BZU Histidine kinase HQN80_RS12365 ENOG410643D UPF0509 protein HQN80_RS12370 ENOG4105N2W Transcriptional regulator HQN80_RS12380 ENOG4108ZJT translation initiation factor, Sui1 HQN80_RS12390 ENOG4105CFV Tetratricopeptide repeat protein HQN80_RS12395 ENOG4105Q4A inner membrane protein yciS HQN80_RS12400 ENOG4105EYK Phosphatidylglycerophosphatase B HQN80_RS12410 ENOG4107QM5 aconitate hydratase HQN80_RS12430 ENOG4107R11 Transcriptional regulator HQN80_RS12435 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) HQN80_RS12440 ENOG4105RKX Protein of unknown function (DUF2498) HQN80_RS12445 ENOG4105ERU peptidase HQN80_RS12450 ENOG4105UBK short-chain dehydrogenase reductase HQN80_RS12455 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase HQN80_RS12460 ENOG4105FE9 pseudouridine synthase HQN80_RS12465 ENOG4107RTD sua5 ycio yrdc ywlc family protein HQN80_RS12470 ENOG4105DB7 PHP domain protein HQN80_RS12480 ENOG4105CRQ synthase (Component I) HQN80_RS12485 ENOG4108EFP Anthranilate synthase component II HQN80_RS12490 ENOG4105DK0 Indole-3-glycerol phosphate synthase HQN80_RS12510 ENOG4108Z9Z response to DNA damage stimulus HQN80_RS12515 ENOG4108N8X transition metal ion binding HQN80_RS12520 ENOG4105EIF outer membrane protein W HQN80_RS12540 ENOG4105NAU thioesterase Superfamily protein HQN80_RS12545 ENOG410822N TonB family HQN80_RS12550 ENOG4105K9H YciI-like protein HQN80_RS12555 ENOG4107SVH Potassium channel protein HQN80_RS12575 ENOG4108JQ7 (ABC) transporter HQN80_RS12580 ENOG4105C3U ABC transporter HQN80_RS12585 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HQN80_RS12590 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HQN80_RS12595 ENOG4108J59 Extracellular solute-binding protein, family 5 HQN80_RS12605 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein HQN80_RS12610 ENOG4105C0A alcohol dehydrogenase HQN80_RS12620 ENOG4108SAU DNA-binding protein H-ns HQN80_RS12625 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase HQN80_RS12630 ENOG4105I93 response regulator HQN80_RS12635 ENOG4105D78 K07001 NTE family protein HQN80_RS12640 ENOG4105K5B UPF0225 protein HQN80_RS12645 ENOG4105CIY formyltetrahydrofolate deformylase HQN80_RS12670 ENOG41076YT nitrate reductase, gamma subunit HQN80_RS12675 ENOG4105R3A Nitrate reductase HQN80_RS12680 ENOG4108IUE nitrate reductase beta subunit HQN80_RS12685 ENOG4105CRU nitrate reductase, alpha subunit HQN80_RS12690 ENOG4105DQQ Major facilitator superfamily MFS_1 HQN80_RS12695 ENOG4105BZU Histidine kinase HQN80_RS12700 ENOG4105WH1 Two component transcriptional regulator luxr family HQN80_RS12705 ENOG4105ID0 Putative invasin HQN80_RS12710 ENOG41090EX DsrE family HQN80_RS12715 ENOG4108NH8 Cation transport protein HQN80_RS12720 ENOG4105WS7 Cation transport regulator HQN80_RS12725 ENOG4105EWV Sodium calcium exchanger membrane region HQN80_RS12745 ENOG41063JG Transcriptional regulator HQN80_RS12750 ENOG4108YY7 Invasion gene expression up-regulator SirB HQN80_RS12765 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) HQN80_RS12780 ENOG4105C5T Phosphoribosyl pyrophosphate synthase HQN80_RS12785 ENOG4105CHH sulfate transporter HQN80_RS12790 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria HQN80_RS12800 ENOG4105C3G gtp-binding protein HQN80_RS12810 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family HQN80_RS12815 ENOG4105CMT Dihydroxyacetone kinase HQN80_RS12820 ENOG4108UTZ Dihydroxyacetone kinase HQN80_RS12825 ENOG4105VDH Dihydroxyacetone kinase HQN80_RS12845 ENOG4108T7K Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity) HQN80_RS12855 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A HQN80_RS12865 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) HQN80_RS12875 ENOG4105ED1 spovr family HQN80_RS12895 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) HQN80_RS12900 ENOG4105KT5 UmuD protein HQN80_RS12915 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase HQN80_RS12925 ENOG41066UD Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium HQN80_RS12930 ENOG4105S66 prophage protein HQN80_RS12940 ENOG4107QMS site-determining protein HQN80_RS12975 ENOG410658X HQN80_RS12995 ENOG4105BZU Histidine kinase HQN80_RS13000 ENOG410738I uncharacterized protein ymgC HQN80_RS13010 ENOG41077SS Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. May serve to stimulate biofilm maturation, probably via the Rcs phosphorelay. Mild overexpression at 16 degrees Celsius increases the production of colanic acid, an exopolysaccharide and matrix component, and reduces adhesive curli fimbriae expression. Both of these effects require RcsB HQN80_RS13015 ENOG4105WKE Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. Partially antagonizes the activities of YmgA and AriR, proteins that, via the Rcs phosphorelay, promote the synthesis of colanic acid, an exopolysaccharide and matrix component HQN80_RS13020 ENOG4105BZU Histidine kinase HQN80_RS13025 ENOG4108XDN Transcriptional regulator HQN80_RS13030 ENOG41064WM Uncharacterized protein YcgX HQN80_RS13045 ENOG4108HMX isocitrate dehydrogenase (NADP) HQN80_RS13055 ENOG4105FBQ ATPase associated with various cellular activities aaa_5 HQN80_RS13125 ENOG4108I1J Integrase HQN80_RS13130 ENOG4108HMX isocitrate dehydrogenase (NADP) HQN80_RS13135 ENOG4108R99 pseudouridine synthase HQN80_RS13155 ENOG4107QTF adenylosuccinate lyase HQN80_RS13160 ENOG4105XJC Two component transcriptional regulator (Winged helix family HQN80_RS13165 ENOG4105IFJ Histidine kinase HQN80_RS13170 ENOG4105EZE Cupin 4 family protein HQN80_RS13190 ENOG4105D38 putrescine abc transporter HQN80_RS13195 ENOG4107RUE extracellular solute-binding protein family 1 HQN80_RS13210 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) HQN80_RS13220 ENOG4105D60 lipoprotein releasing system transmembrane protein HQN80_RS13225 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) HQN80_RS13230 ENOG4105D60 lipoprotein releasing system transmembrane protein HQN80_RS13235 ENOG4105IQC Inner membrane protein YcfT HQN80_RS13240 ENOG4108JA2 transcriptioN-repair coupling factor HQN80_RS13245 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein HQN80_RS13250 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction HQN80_RS13255 ENOG4108IND Tetr family transcriptional regulator HQN80_RS13260 ENOG4107MBR 17 kDa surface antigen HQN80_RS13265 ENOG4105CEP NADH dehydrogenase HQN80_RS13280 ENOG4108RUM thiamine kinase HQN80_RS13285 ENOG4108WEF Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity) HQN80_RS13290 ENOG41090DQ Lipoprotein HQN80_RS13295 ENOG4105K59 histidine triad (HIT) protein HQN80_RS13300 ENOG4105CNM Receptor HQN80_RS13305 ENOG4105CI1 PTS System HQN80_RS13310 ENOG4105F8V Hydrolase, tatD family HQN80_RS13315 ENOG4107QRG dna polymerase iii HQN80_RS13325 ENOG4105HHA aminodeoxychorismate lyase HQN80_RS13330 ENOG4105YAZ 4-amino-4-deoxychorismate lyase HQN80_RS13335 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) HQN80_RS13340 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) HQN80_RS13345 ENOG4105CHR reductase HQN80_RS13350 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase HQN80_RS13370 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein HQN80_RS13375 ENOG4108UHJ MAF-like protein HQN80_RS13380 ENOG4105EI2 Pseudouridine synthase HQN80_RS13385 ENOG4107QQB Ribonuclease E HQN80_RS13390 ENOG4105DTJ flagellar hook-associated protein HQN80_RS13395 ENOG4105E1Q flagellar hook-associated protein HQN80_RS13400 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj HQN80_RS13415 ENOG4105CGA flagellar basal-body rod protein FlgG HQN80_RS13420 ENOG4108KPB Flagellar basal-body rod protein FlgF HQN80_RS13425 ENOG4105BZE flagellar hook protein, FlgE HQN80_RS13430 ENOG4105W00 Flagellar hook capping protein HQN80_RS13435 ENOG4108ZC9 flagellar basal-body rod protein flgc HQN80_RS13440 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) HQN80_RS13445 ENOG4105CKS Flagella basal body P-ring formation protein flgA HQN80_RS13450 ENOG4105M9M anti-sigma28 factor FlgM HQN80_RS13455 ENOG4105QVD Flagella synthesis protein FlgN HQN80_RS13460 ENOG4105CJR Integral membrane protein (MviN HQN80_RS13465 ENOG4105EP9 oxidoreductase HQN80_RS13475 ENOG4105D9U N-acetyltransferase HQN80_RS13485 ENOG4105E9S glutaredoxin 2 HQN80_RS13490 ENOG4105F3T (LipO)protein HQN80_RS13500 ENOG4105MEA DNA damage-inducible protein i HQN80_RS13505 ENOG4105PVA Biofilm formation regulatory protein BssS HQN80_RS13515 ENOG4106974 biofilm formation HQN80_RS13520 ENOG4105DS1 cytochrome b561 HQN80_RS13525 ENOG4108YYC ycei family HQN80_RS13535 ENOG4105D1S lipid A biosynthesis HQN80_RS13545 ENOG4108W47 Acidic protein msyB HQN80_RS13550 ENOG4105NAC (LipO)protein HQN80_RS13555 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) HQN80_RS13570 ENOG4107RZC phospholipase d HQN80_RS13575 ENOG4108UVJ appr-1-p processing domain protein HQN80_RS13590 ENOG4105G76 Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin HQN80_RS13595 ENOG4108U0V Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin. The minor subunit is the nucleation component of curlin monomers HQN80_RS13600 ENOG41086KC Transcriptional regulator HQN80_RS13605 ENOG4108XDW curli assembly protein CsgE HQN80_RS13610 ENOG4108WYR Curli production assembly transport component, CsgF HQN80_RS13615 ENOG4105P8Q Curli production assembly transport component CsgG HQN80_RS13620 ENOG4108UQ5 membrane protein YcdZ HQN80_RS13625 ENOG4107XHZ cytoplasmic chaperone TorD family protein HQN80_RS13650 ENOG4108T85 Membrane HQN80_RS13665 ENOG4105BZU Histidine kinase HQN80_RS13670 ENOG4108TUY outer membrane protein PgaA HQN80_RS13675 ENOG4107BJW polysaccharide deacetylase HQN80_RS13680 ENOG4105CND Glycosyl transferase, family 2 HQN80_RS13690 ENOG4105D5M phosphate starvation-inducible protein HQN80_RS13700 ENOG410650H (LipO)protein HQN80_RS13715 ENOG4105CK7 Sodium proline symporter HQN80_RS13720 ENOG4105C26 Dehydrogenase HQN80_RS13725 ENOG4108R86 Transcriptional regulator HQN80_RS13760 ENOG4105C2W permease HQN80_RS13765 ENOG4105XF5 Escherichia coli IMT2125 genomic chromosome, IMT2125 HQN80_RS13780 ENOG4105XH3 HQN80_RS13785 ENOG4105D6F Phosphatase HQN80_RS13810 ENOG4108J2R molybdopterin oxidoreductase HQN80_RS13815 ENOG4105CUW cytochrome C-TYPE protein HQN80_RS13820 ENOG4106WF9 DNA-binding transcriptional regulator TorR HQN80_RS13825 ENOG4108SV3 Tmao reductase system periplasmic protein tort HQN80_RS13830 ENOG4105BZU Histidine kinase HQN80_RS13835 ENOG4105HEE Binding Domain protein HQN80_RS13840 ENOG4106H71 Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation HQN80_RS13855 ENOG4105VEQ Cold shock protein HQN80_RS13860 ENOG41060EU Cold shock-like protein HQN80_RS13870 ENOG4108Y9B (LipO)protein HQN80_RS13875 ENOG4108W78 Pfam:DUF1017 HQN80_RS13880 ENOG4105E3R (LipO)protein HQN80_RS13885 ENOG4105DAY polysaccharide export protein HQN80_RS13890 ENOG4107ZF2 Phosphatase HQN80_RS13895 ENOG4108F2G Chain length determinant protein HQN80_RS13900 ENOG4105D6F Phosphatase HQN80_RS13910 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii HQN80_RS13915 ENOG4105C4M (Ubiquinol oxidase) subunit I HQN80_RS13920 ENOG4105MVP hydrogenase-1 operon protein HyaF HQN80_RS13925 ENOG4108VXY Hydrogenase-1 operon protein HyaE HQN80_RS13930 ENOG4108USZ hydrogenase HQN80_RS13935 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit HQN80_RS13940 ENOG4105DPX Hydrogenase, large subunit HQN80_RS13945 ENOG4105E3S small subunit HQN80_RS13955 ENOG4108MN8 Membrane HQN80_RS13960 ENOG4108Z0T Part of a sulfur-relay system (By similarity) HQN80_RS13965 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 HQN80_RS13980 ENOG4105K4P CoA-binding domain protein HQN80_RS13995 ENOG41088T4 Helicase IV HQN80_RS14000 ENOG410901E Membrane HQN80_RS14005 ENOG4105EM2 membrane HQN80_RS14010 ENOG4108RZ1 DNA transformation protein HQN80_RS14020 ENOG4105UYK outer membrane protein a HQN80_RS14030 ENOG4105DAN ATP-dependent protease HQN80_RS14040 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) HQN80_RS14045 ENOG4108Q2G (LipO)protein HQN80_RS14050 ENOG4105DY2 Paraquat-inducible protein b HQN80_RS14055 ENOG4105F1S paraquat-inducible protein a HQN80_RS14060 ENOG4105C5H ABC transporter HQN80_RS14070 ENOG4105QVC MOSC domain-containing protein HQN80_RS14075 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) HQN80_RS14085 ENOG4106PH7 chaperone HQN80_RS14090 ENOG4105MX3 Fimbrial HQN80_RS14095 ENOG4105Q7J Fimbrial HQN80_RS14100 ENOG4108MDY Fimbrial HQN80_RS14105 ENOG4105CW0 outer membrane usher protein HQN80_RS14110 ENOG4106JJN Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. Could be required for the biogenesis of the ElfA fimbriae HQN80_RS14115 ENOG41071VI Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. ElfA is the major fimbrial subunit produced by this operon HQN80_RS14120 ENOG4108UZX fmn reductase HQN80_RS14125 ENOG4105GVF (ABC) transporter HQN80_RS14135 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component HQN80_RS14145 ENOG4105CD8 aminopeptidase N HQN80_RS14160 ENOG4105FCK Membrane HQN80_RS14165 ENOG4105CGF Aromatic amino acid aminotransferase HQN80_RS14170 ENOG4105C5X domain protein HQN80_RS14175 ENOG4105EAQ (twin-arginine translocation) pathway signal HQN80_RS14180 ENOG4105DIT ErfK YbiS YcfS YnhG family protein HQN80_RS14190 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) HQN80_RS14200 ENOG4106371 Methyltransferase HQN80_RS14205 ENOG4107S90 membrAne HQN80_RS14210 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups HQN80_RS14225 ENOG4105T0Z Conserved Protein HQN80_RS14235 ENOG4105BZ1 (ABC) transporter HQN80_RS14240 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 HQN80_RS14250 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) HQN80_RS14260 ENOG4108K0D peptidase, M48 HQN80_RS14275 ENOG4107VMU Membrane HQN80_RS14280 ENOG4105DDY UPF0142 protein ycaO HQN80_RS14285 ENOG4105TMB Formate nitrite transporter HQN80_RS14290 ENOG4105C6N Formate acetyltransferase HQN80_RS14295 ENOG4105F1A Pyruvate formate-lyase HQN80_RS14300 ENOG4108X0B nad(p)h dehydrogenase (quinone) HQN80_RS14305 ENOG410642W LysR family Transcriptional regulator HQN80_RS14310 ENOG4105E5D amino acid HQN80_RS14320 ENOG4105CHJ isochorismatase hydrolase HQN80_RS14325 ENOG4107KGK dmso reductase anchor subunit HQN80_RS14330 ENOG4105QAX Iron-sulfur HQN80_RS14335 ENOG4107QY8 reductase HQN80_RS14345 ENOG4105D1H recombination factor protein RarA HQN80_RS14355 ENOG4105CNU cell division protein FtsK HQN80_RS14365 ENOG4105C3M thioredoxin reductase HQN80_RS14370 ENOG4108JJ9 ABC, transporter HQN80_RS14375 ENOG4108JJ8 (ABC) transporter HQN80_RS14385 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) HQN80_RS14395 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit HQN80_RS14405 ENOG4105VEQ Cold shock protein HQN80_RS14410 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) HQN80_RS14415 ENOG4105DJY efflux transporter, rnd family, mfp subunit HQN80_RS14420 ENOG4108MJ5 VirK protein HQN80_RS14425 ENOG4105CPB ATP-dependent endonuclease of the OLD family HQN80_RS14430 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) HQN80_RS14435 ENOG4105DWU Membrane HQN80_RS14445 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) HQN80_RS14450 ENOG4105C7K acetolactate synthase HQN80_RS14455 ENOG4105C5W Aldolase HQN80_RS14460 ENOG4105CGD Nad-dependent epimerase dehydratase HQN80_RS14465 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase HQN80_RS14470 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase HQN80_RS14480 ENOG41064MM (LipO)protein HQN80_RS14485 ENOG4105E5Z arginine transporter ATP-binding subunit HQN80_RS14490 ENOG4106PMH Extracellular solute-binding protein family 3 HQN80_RS14495 ENOG4105GBT ABC transporter HQN80_RS14500 ENOG4105DMR ABC, transporter HQN80_RS14505 ENOG4106TNF Periplasmic binding protein HQN80_RS14515 ENOG4105RBQ inner membrane protein ybjO HQN80_RS14520 ENOG4105D38 putrescine abc transporter HQN80_RS14525 ENOG4105F38 ABC transporter, permease HQN80_RS14530 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) HQN80_RS14535 ENOG4107RUE extracellular solute-binding protein family 1 HQN80_RS14540 ENOG4108RMJ sensory transduction regulator HQN80_RS14550 ENOG4108DBC nitroreductase HQN80_RS14555 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress HQN80_RS14560 ENOG41090BQ Glutaredoxin HQN80_RS14565 ENOG4105GWF inner membrane protein YbjM HQN80_RS14575 ENOG4108RFG Tetr family transcriptional regulator HQN80_RS14580 ENOG4106UW1 Major Facilitator superfamily HQN80_RS14585 ENOG4108HCJ Hydrolase HQN80_RS14595 ENOG4107QF7 multi-drug HQN80_RS14600 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase HQN80_RS14605 ENOG4107FB0 transcriptional regulator DeoR family HQN80_RS14610 ENOG4105DZ1 carboxypeptidase HQN80_RS14615 ENOG4108TGY Glutathione S-transferase HQN80_RS14620 ENOG4105D8V Glucose sorbosone dehydrogenase HQN80_RS14625 ENOG4105UFT Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway HQN80_RS14635 ENOG41064RH membrane protein YliF HQN80_RS14640 ENOG4105BZU Histidine kinase HQN80_RS14665 ENOG4105D44 asparaginase HQN80_RS14670 ENOG4105CVM Molybdenum cofactor synthesis domain protein HQN80_RS14675 ENOG4105D06 uba thif-type nad fad binding protein HQN80_RS14680 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) HQN80_RS14685 ENOG4105F1A Pyruvate formate-lyase HQN80_RS14695 ENOG4108HCJ Hydrolase HQN80_RS14700 ENOG41072TH Protein of unknown function (DUF1479) HQN80_RS14705 ENOG4105C5H ABC transporter HQN80_RS14710 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein HQN80_RS14715 ENOG4105F4P )-transporter HQN80_RS14720 ENOG4105KST dependent repressor HQN80_RS14730 ENOG4108I6E Sulfatase HQN80_RS14735 ENOG4108T1M outer membrane protein x HQN80_RS14745 ENOG4107AQZ Membrane HQN80_RS14755 ENOG4107R0W ABC transporter HQN80_RS14760 ENOG4105E5Q amino acid AbC transporter HQN80_RS14765 ENOG4105CDA abc transporter atp-binding protein HQN80_RS14770 ENOG4105D8X mechanosensitive ion channel HQN80_RS14780 ENOG4105ZY9 UPF0379 protein ybiM HQN80_RS14785 ENOG4108IU3 tonb-dependent siderophore receptor HQN80_RS14795 ENOG4105KSC Transcriptional regulator, TraR DksA family HQN80_RS14800 ENOG4105VR4 UPF0379 protein ybiJ HQN80_RS14805 ENOG4105DG4 malate L-lactate dehydrogenase HQN80_RS14810 ENOG4108MTB glycosyl transferase family HQN80_RS14815 ENOG4105DVT helicase HQN80_RS14820 ENOG4108UV1 cellular component movement HQN80_RS14825 ENOG4105C1J atp-dependent rna helicase HQN80_RS14830 ENOG4107MVR Transcriptional regulator HQN80_RS14840 ENOG4105CJ1 ABC, transporter HQN80_RS14845 ENOG4107QWP ABC-2 type transporter HQN80_RS14850 ENOG4107QWP ABC-2 type transporter HQN80_RS14855 ENOG4105I9U inner membrane protein ybhQ HQN80_RS14860 ENOG4105X23 Endonuclease Exonuclease phosphatase HQN80_RS14865 ENOG4105DZQ phospholipase D Transphosphatidylase HQN80_RS14870 ENOG4107UXM Membrane HQN80_RS14890 ENOG4105HFZ Membrane HQN80_RS14895 ENOG4108ZAF Molybdopterin HQN80_RS14900 ENOG4105M00 molybdopterin converting factor, subunit 1 HQN80_RS14910 ENOG4108RIR Molybdenum cofactor biosynthesis protein HQN80_RS14920 ENOG4105CHW UPF0052 protein HQN80_RS14930 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) HQN80_RS14935 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) HQN80_RS14940 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) HQN80_RS14950 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) HQN80_RS14955 ENOG4108V1U phospholipid-binding protein HQN80_RS14960 ENOG4106KTS Inner membrane protein yeaI HQN80_RS14970 ENOG4108WF3 methyltransferase HQN80_RS14985 ENOG4105FKG DNA packaging protein HQN80_RS14990 ENOG4106YSC HQN80_RS14995 ENOG41064WM Uncharacterized protein YcgX HQN80_RS15005 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 HQN80_RS15010 ENOG4105KUS lysozyme HQN80_RS15015 ENOG4105QFS Lysis protein S homolog from lambdoid prophage HQN80_RS15025 ENOG4107SEY Conserved Protein HQN80_RS15035 ENOG4105HRS Antitermination protein HQN80_RS15050 ENOG4105RWQ Protein of unknown function (DUF1364) HQN80_RS15055 ENOG410757E Protein NinE homolog from lambdoid prophage DLP12 HQN80_RS15060 ENOG4108V2F protein ybcN in lambdoid DLP12 prophage regi HQN80_RS15175 ENOG4108I1J Integrase HQN80_RS15180 ENOG4105NBR Pectinesterase HQN80_RS15185 ENOG4107QM5 aconitate hydratase HQN80_RS15190 ENOG4107QPK )-transporter HQN80_RS15195 ENOG4105C7F AcnD-accessory protein PrpF HQN80_RS15200 ENOG4105F04 LysR family Transcriptional regulator HQN80_RS15210 ENOG4108K4B hydrolase HQN80_RS15215 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) HQN80_RS15220 ENOG4105E0C molybdate abc transporter HQN80_RS15225 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein HQN80_RS15235 ENOG4105F4R Transcriptional regulator mode HQN80_RS15240 ENOG4105DKW ABC transporter HQN80_RS15245 ENOG4105CMR udp-glucose 4-epimerase HQN80_RS15250 ENOG4105F0Z galactose-1-phosphate uridylyltransferase HQN80_RS15260 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) HQN80_RS15270 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) HQN80_RS15275 ENOG4105JND homeobox protein HQN80_RS15280 ENOG4105PGM cation diffusion facilitator family transporter HQN80_RS15285 ENOG4106Z1T Nicotinamide Mononucleotide Transporter HQN80_RS15335 ENOG4105UFD tol-pal system protein YbgF HQN80_RS15340 ENOG4105KCK Peptidoglycan-associated lipoprotein HQN80_RS15350 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA HQN80_RS15360 ENOG4105E02 MotA TolQ exbB proton channel HQN80_RS15365 ENOG4107YD3 Thioesterase HQN80_RS15370 ENOG4105KJB cyd operon protein YbgE HQN80_RS15380 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii HQN80_RS15385 ENOG4105C4M (Ubiquinol oxidase) subunit I HQN80_RS15390 ENOG4105C8I hydrolase, family 38 HQN80_RS15395 ENOG4105DM4 PTS System HQN80_RS15400 ENOG4105FDP GntR family transcriptional regulator HQN80_RS15405 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha HQN80_RS15415 ENOG4105C7S Dehydrogenase HQN80_RS15420 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 HQN80_RS15425 ENOG4105E33 succinate dehydrogenase HQN80_RS15430 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) HQN80_RS15435 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein HQN80_RS15440 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit HQN80_RS15450 ENOG4105BZN citrate synthase HQN80_RS15455 ENOG4106UBK fimbrial-like adhesin protein HQN80_RS15460 ENOG4106PG1 outer membrane usher protein HQN80_RS15465 ENOG4108TTM chaperone HQN80_RS15470 ENOG4108MY7 Fimbrial HQN80_RS15475 ENOG4108KK1 membrane protein AbrB duplication HQN80_RS15485 ENOG4105E7W lamb ycsf family protein HQN80_RS15490 ENOG4107R7A Allophanate hydrolase subunit 2 HQN80_RS15495 ENOG4105P4J Allophanate hydrolase, subunit 1 HQN80_RS15500 ENOG4107QNR UPF0135 protein HQN80_RS15505 ENOG4105DUX Transporter HQN80_RS15510 ENOG4105CVP deoxyribo-dipyrimidine photolyase HQN80_RS15515 ENOG4107SEY Conserved Protein HQN80_RS15530 ENOG4106R09 HQN80_RS15535 ENOG4105CNA YD repeat protein HQN80_RS15540 ENOG41079JQ Membrane HQN80_RS15545 ENOG4105CNA YD repeat protein HQN80_RS15550 ENOG4105XIQ Protein of unknown function (DUF2517) HQN80_RS15565 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) HQN80_RS15575 ENOG4105C08 Histidine kinase HQN80_RS15580 ENOG4105EEX Two component transcriptional regulator (Winged helix family HQN80_RS15590 ENOG4105CXN decarboxylase HQN80_RS15595 ENOG4105D5Q Arginine ornithine antiporter HQN80_RS15600 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 HQN80_RS15605 ENOG4107CDU Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity) HQN80_RS15610 ENOG4105EV9 Alpha Beta Hydrolase HQN80_RS15615 ENOG4105NNH LexA regulated protein HQN80_RS15620 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) HQN80_RS15630 ENOG41090R7 Ferric uptake HQN80_RS15635 ENOG4105GX6 (LipO)protein HQN80_RS15650 ENOG4105CI1 PTS System HQN80_RS15660 ENOG4105CE4 GlcNAc 6-P deacetylase HQN80_RS15665 ENOG4105E2R ROK family HQN80_RS15670 ENOG4105D4U had-superfamily hydrolase, subfamily iia HQN80_RS15675 ENOG4105CAQ asparagine synthetase HQN80_RS15715 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family HQN80_RS15725 ENOG4105C9A Phoh family HQN80_RS15735 ENOG4108JU5 Magnesium and cobalt efflux protein HQN80_RS15740 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) HQN80_RS15750 ENOG4107RP9 extracellular solute-binding protein, family 3 HQN80_RS15755 ENOG4105EAD ABC transporter HQN80_RS15760 ENOG4105DRP amino acid AbC transporter HQN80_RS15765 ENOG4105CDA abc transporter atp-binding protein HQN80_RS15790 ENOG4105QFC Hsc56 co-chaperone of HscC HQN80_RS15795 ENOG41069CF Protein of unknown function (DUF1266) HQN80_RS15800 ENOG4107JFD Sel1 repeat HQN80_RS15805 ENOG4105QFC Hsc56 co-chaperone of HscC HQN80_RS15810 ENOG41069CF Protein of unknown function (DUF1266) HQN80_RS15815 ENOG4105EUU Sel1 domain protein repeat-containing protein HQN80_RS15820 ENOG4107PAI alpha helical protein HQN80_RS15835 ENOG4105DJF DNA polymerase III, delta' subunit HQN80_RS15845 ENOG4108TGR phosphatase HQN80_RS15850 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) HQN80_RS15860 ENOG4105CJN penicillin-binding protein HQN80_RS15865 ENOG4105CNI cell division protein FtsW HQN80_RS15870 ENOG4105K6T rare lipoprotein A HQN80_RS15875 ENOG4105DZ1 carboxypeptidase HQN80_RS15890 ENOG41064T2 transcriptional regulator, lysR family HQN80_RS15900 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) HQN80_RS15910 ENOG4107Z6W Protein CrcB homolog HQN80_RS15920 ENOG41079UR PagP is required both for biosynthesis of hepta-acylated lipid A species containing palmitate and for resistance to cationic antimicrobial peptides (CAMPs). It catalyzes the transfer of a palmitate chain (16 0) from the sn-1 position of a glycerophospholipid to the free hydroxyl group of the (R)-3- hydroxymyristate chain at position 2 of lipid A (endotoxin) (By similarity) HQN80_RS15925 ENOG4105CEE C4-dicarboxylate transporter HQN80_RS15930 ENOG4106YYS transcriptional regulatory protein HQN80_RS15935 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism HQN80_RS15940 ENOG4105DUA (citrate (pro-3S)-lyase ligase HQN80_RS15950 ENOG4105CI0 Citrate lyase HQN80_RS15955 ENOG4105CHY citrate lyase, alpha HQN80_RS15970 ENOG4107QPK )-transporter HQN80_RS15975 ENOG4105KTS ribonuclease HQN80_RS15980 ENOG4105NXH GreA GreB family elongation factor HQN80_RS15985 ENOG4105E2A Dehydrogenase HQN80_RS15990 ENOG4108U51 Universal stress protein HQN80_RS15995 ENOG4108JU3 Alkyl hydroperoxide reductase HQN80_RS16000 ENOG4105D3R alkyl hydroperoxide reductase HQN80_RS16005 ENOG4108KHN disulfide isomerase, thiol-disulfide oxidase HQN80_RS16025 ENOG4105BZV Phosphoadenosine phosphosulfate reductase HQN80_RS16030 ENOG4105GTN ParB Domain Protein Nuclease HQN80_RS16035 ENOG4105CHM Aminotransferase HQN80_RS16040 ENOG4107SCQ Iron-containing alcohol dehydrogenase HQN80_RS16045 ENOG4105VCD cytoplasmic protein HQN80_RS16050 ENOG4105D22 carbon starvation protein HQN80_RS16055 ENOG4108TZA Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules (By similarity) HQN80_RS16060 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase HQN80_RS16065 ENOG4105WQI isochorismatase HQN80_RS16070 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase HQN80_RS16075 ENOG4105E4F Isochorismate synthase HQN80_RS16080 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein HQN80_RS16090 ENOG4105DQ5 transport system permease protein HQN80_RS16095 ENOG4105TVJ transport system, permease HQN80_RS16100 ENOG4105E0A ABC, transporter HQN80_RS16105 ENOG4108QY5 Ferric enterobactin transport protein HQN80_RS16110 ENOG4105C0W non-ribosomal peptide synthetase HQN80_RS16115 ENOG41085A6 mbth domain-containing protein HQN80_RS16120 ENOG4105E93 esterase HQN80_RS16125 ENOG4107RNH Outer membrane receptor FepA HQN80_RS16130 ENOG4108TSE Transferase HQN80_RS16135 ENOG4107635 Hok Gef family protein HQN80_RS16140 ENOG4106KXD ATP-dependent carboxylate-amine ligase (By similarity) HQN80_RS16145 ENOG4105WQ6 Membrane HQN80_RS16150 ENOG4105MSB protein, conserved in bacteria HQN80_RS16155 ENOG4108RCM Nitroreductase HQN80_RS16160 ENOG4105CUY Mechanosensitive ion channel HQN80_RS16165 ENOG4105C85 amino acid HQN80_RS16170 ENOG4108IJF Heavy metal efflux pump, CzcA HQN80_RS16175 ENOG4105EP1 Efflux transporter rnd family, mfp subunit HQN80_RS16180 ENOG410624V efflux system protein HQN80_RS16185 ENOG4105ENJ RND efflux system, outer membrane lipoprotein HQN80_RS16190 ENOG4105CK6 Two component transcriptional regulator (Winged helix family HQN80_RS16195 ENOG4105GR3 Histidine kinase HQN80_RS16215 ENOG4105CNA YD repeat protein HQN80_RS16230 ENOG410600T transposase HQN80_RS16240 ENOG41090FC Bacteriophage N4 receptor, outer membrane subunit HQN80_RS16245 ENOG4105QUW HQN80_RS16260 ENOG4108Q9V regulatoR HQN80_RS16265 ENOG4108ZI2 Fimbrial protein HQN80_RS16270 ENOG4108M66 Involved in regulation of length and mediation of adhesion of SfmA fimbriae (but not necessary for the production of fimbriae). Seems to be mannose binding adhesin (By similarity) HQN80_RS16280 ENOG4108AF8 Chaperone HQN80_RS16285 ENOG4108WDE Fimbrial protein HQN80_RS16290 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) HQN80_RS16295 ENOG4105WQ3 Rna-binding protein HQN80_RS16300 ENOG4105S2T inner membrane protein YbcI HQN80_RS16310 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) HQN80_RS16320 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) HQN80_RS16325 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit HQN80_RS16330 ENOG4105C5B carbamate kinase HQN80_RS16335 ENOG4105G5A Protein of unknown function (DUF2877) HQN80_RS16340 ENOG4107REC cytoplasmic protein HQN80_RS16345 ENOG4107R1Q Membrane protein FdrA HQN80_RS16350 ENOG4105DG4 malate L-lactate dehydrogenase HQN80_RS16355 ENOG4105CE7 Amidase, hydantoinase carbamoylase family HQN80_RS16360 ENOG4105S0E allantoin catabolism protein HQN80_RS16365 ENOG4105BZW Glycerate kinase HQN80_RS16370 ENOG4105DTE Xanthine uracil vitamin C permease HQN80_RS16380 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease HQN80_RS16385 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase HQN80_RS16390 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) HQN80_RS16395 ENOG41060W2 glyoxylate carboligase HQN80_RS16400 ENOG4108N16 Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region HQN80_RS16410 ENOG4107653 Transcriptional regulator HQN80_RS16420 ENOG4105CV6 ABC transporter, permease HQN80_RS16425 ENOG4108I0Y (ABC) transporter HQN80_RS16430 ENOG4108UJV acyl-CoA thioesterase i HQN80_RS16435 ENOG4105E1F short-chain dehydrogenase reductase HQN80_RS16440 ENOG4107QR8 Thioredoxin HQN80_RS16445 ENOG4105C4B ABC transporter, permease HQN80_RS16450 ENOG41083J0 (ABC) transporter HQN80_RS16455 ENOG4107QX8 SPFH domain, Band 7 family protein HQN80_RS16460 ENOG4105G5H Membrane HQN80_RS16465 ENOG4108Z6Z Transcriptional regulator HQN80_RS16470 ENOG4107RY6 amino acid HQN80_RS16475 ENOG4105CSV Glutaminase HQN80_RS16480 ENOG4105C59 p-type ATPase HQN80_RS16485 ENOG41081XE plasmid maintenance system antidote protein, xre family HQN80_RS16490 ENOG4105MBR gumn family HQN80_RS16495 ENOG4108Z66 YbaK ebsC protein HQN80_RS16500 ENOG4105CGH 5'-nucleotidase HQN80_RS16505 ENOG4105EU0 Major facilitator Superfamily HQN80_RS16510 ENOG4105CKD glutathione-regulated potassium-efflux system protein HQN80_RS16515 ENOG4107RE1 Inosine-guanosine kinase HQN80_RS16550 ENOG4107QMP dna polymerase iii subunits gamma and tau HQN80_RS16560 ENOG4105WD1 Membrane HQN80_RS16565 ENOG4108URS primosomal replication protein n'' HQN80_RS16570 ENOG4106428 Protein of unknown function (DUF2496) HQN80_RS16575 ENOG4105EGS Mechanosensitive ion channel HQN80_RS16580 ENOG4107XI7 Tetr family transcriptional regulator HQN80_RS16585 ENOG4105C1P efflux transporter, rnd family, mfp subunit HQN80_RS16590 ENOG4105BZS acriflavin resistance protein HQN80_RS16595 ENOG4108UKR Biofilm formation regulator YbaJ HQN80_RS16600 ENOG4105KF5 hemolysin expression-modulating protein HQN80_RS16605 ENOG4108UW5 maltose o-acetyltransferase HQN80_RS16610 ENOG4105GSJ Inner membrane protein ylaC HQN80_RS16615 ENOG41066DG (EAL) domain protein HQN80_RS16620 ENOG4105KCV RNA signal recognition particle 4.5S RNA HQN80_RS16630 ENOG41080UX Methyltransferase HQN80_RS16635 ENOG4108MNP Glycoprotein polysaccharide metabolism HQN80_RS16640 ENOG4105C29 acyl-CoA thioesterase HQN80_RS16645 ENOG4105BZU Histidine kinase HQN80_RS16650 ENOG4108YZA Nitrogen regulatory protein pii HQN80_RS16655 ENOG4105BZ1 (ABC) transporter HQN80_RS16660 ENOG4105BZ1 (ABC) transporter HQN80_RS16665 ENOG4108XM1 transcriptional regulator AsnC family HQN80_RS16675 ENOG4108NFA extracellular solute-binding protein HQN80_RS16685 ENOG4108TGP Thioesterase superfamily protein HQN80_RS16690 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein HQN80_RS16695 ENOG4105EIN peptidylprolyl cis-trans isomerase HQN80_RS16700 ENOG4105K70 DNA-binding protein HQN80_RS16705 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) HQN80_RS16725 ENOG4105M85 Bola protein HQN80_RS16730 ENOG4105IEY (LipO)protein HQN80_RS16735 ENOG4105EYM Major Facilitator superfamily HQN80_RS16740 ENOG4105E2S oxidase) subunit II HQN80_RS16745 ENOG4105BZ9 Cytochrome C oxidase, subunit I HQN80_RS16750 ENOG4105CCU oxidase (Subunit III) HQN80_RS16755 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) HQN80_RS16765 ENOG4107RDB Major Facilitator HQN80_RS16775 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) HQN80_RS16780 ENOG4107S0N DJ-1 family HQN80_RS16795 ENOG4105CTB Polyprenyl synthetase HQN80_RS16805 ENOG4105CPC Aldo Keto reductase HQN80_RS16810 ENOG4108ZAI phosphatidylglycerophosphatase a HQN80_RS16815 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) HQN80_RS16825 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) HQN80_RS16830 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) HQN80_RS16840 ENOG4108KIC (LipO)protein HQN80_RS16845 ENOG4105DRB nucleoside-specific channel-forming protein HQN80_RS16850 ENOG4105N1F Hnh endonuclease HQN80_RS16855 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) HQN80_RS16860 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) HQN80_RS16865 ENOG4105VIE preprotein translocase, subunit YajC HQN80_RS16885 ENOG4107R28 alpha amylase, catalytic region HQN80_RS16890 ENOG4105C85 amino acid HQN80_RS16895 ENOG4105CWM branched-chain amino acid transport system II carrier protein HQN80_RS16900 ENOG4105BZU Histidine kinase HQN80_RS16905 ENOG4105CK6 Two component transcriptional regulator (Winged helix family HQN80_RS16910 ENOG4107RH8 nuclease SbcCD subunit D HQN80_RS16915 ENOG4105EYH Exonuclease HQN80_RS16920 ENOG4105F27 Major Facilitator HQN80_RS16925 ENOG4105DKQ ROK family HQN80_RS16950 ENOG4105HBA AroM protein HQN80_RS16955 ENOG4105SS3 HQN80_RS16965 ENOG4108UPT UPF0178 protein HQN80_RS16970 ENOG4105II7 pyrroline-5-carboxylate reductase HQN80_RS16975 ENOG4105BZU Histidine kinase HQN80_RS16980 ENOG4105VIF phosphate starvation-inducible protein HQN80_RS16985 ENOG4105G6Z alkaline phosphatase HQN80_RS17005 ENOG4105CPF Cell wall formation (By similarity) HQN80_RS17010 ENOG4105UNH Membrane HQN80_RS17015 ENOG4105FR5 inner membrane protein YaiY HQN80_RS17020 ENOG4107QS8 (LipO)protein HQN80_RS17025 ENOG4108DQG in Escherichia coli SbmA is involved in uptake of microcin J25 HQN80_RS17030 ENOG4107R6D beta-lactam binding protein AmpH HQN80_RS17035 ENOG4108PNB DNA-binding transcriptional regulator HQN80_RS17050 ENOG4105D52 delta-aminolevulinic acid dehydratase HQN80_RS17055 ENOG4105E2B Taurine dioxygenase HQN80_RS17060 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component HQN80_RS17070 ENOG4106FTQ Taurine ABC transporter, periplasmic HQN80_RS17075 ENOG4107W19 lmbE family HQN80_RS17080 ENOG4108PBI Polysaccharide metabolism HQN80_RS17090 ENOG4105SRB Uncharacterized protein yaiO HQN80_RS17110 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme HQN80_RS17115 ENOG4108SC4 )-transporter HQN80_RS17135 ENOG4106HB6 Alpha beta hydrolase HQN80_RS17150 ENOG4108K2P TRANSCRIPTIONal HQN80_RS17155 ENOG4105ETE Transcriptional regulator (LacI family HQN80_RS17165 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) HQN80_RS17170 ENOG4108UW5 maltose o-acetyltransferase HQN80_RS17175 ENOG4105DJ2 Major Facilitator Superfamily HQN80_RS17185 ENOG4107B2H carbonic anhydrase HQN80_RS17190 ENOG4105DND Transcriptional regulator HQN80_RS17195 ENOG4105DZC cytosine deaminase HQN80_RS17200 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin HQN80_RS17205 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) HQN80_RS17210 ENOG4105DXD 2-methylcitrate dehydratase HQN80_RS17215 ENOG4105BZN citrate synthase HQN80_RS17220 ENOG4105CR4 methylisocitrate lyase HQN80_RS17225 ENOG4108JU7 Transcriptional regulator HQN80_RS17230 ENOG4105TDT uncharacterized protein yahO HQN80_RS17235 ENOG4105E82 cytochrome subunit of dehydrogenase HQN80_RS17250 ENOG4105DQ4 alcohol dehydrogenase HQN80_RS17255 ENOG4105DZC cytosine deaminase HQN80_RS17260 ENOG4105C5B carbamate kinase HQN80_RS17265 ENOG4107REC cytoplasmic protein HQN80_RS17285 ENOG4105N16 Protein of unknown function (DUF2877) HQN80_RS17290 ENOG4107SNB ankyrin repeat protein YahD HQN80_RS17295 ENOG4105SZ2 membrAne HQN80_RS17300 ENOG4108NUU Transcriptional regulator HQN80_RS17305 ENOG4105BZU Histidine kinase HQN80_RS17315 ENOG4105C94 Transporter HQN80_RS17325 ENOG4105C26 Dehydrogenase HQN80_RS17330 ENOG4105CZ6 Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity) HQN80_RS17340 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) HQN80_RS17345 ENOG4107QR9 Iron-sulfur cluster binding protein HQN80_RS17350 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) HQN80_RS17355 ENOG4108K01 transcriptional regulator HQN80_RS17360 ENOG4107QN2 dihydrolipoyl dehydrogenase HQN80_RS17365 ENOG41066GK UPF0379 protein ykgI HQN80_RS17370 ENOG4108KBJ Inner membrane protein YkgB HQN80_RS17425 ENOG4108N3D putative enzyme HQN80_RS17430 ENOG4106PYX Receptor HQN80_RS17435 ENOG4108UD7 cell wall organization HQN80_RS17440 ENOG4105PI0 Ferredoxin HQN80_RS17445 ENOG4105R3P Inner membrane protein yagU HQN80_RS17450 ENOG4107XKX isoquinoline 1-oxidoreductase, alpha subunit HQN80_RS17455 ENOG4105DIP Molybdopterin dehydrogenase FAD-binding HQN80_RS17460 ENOG4105C7W Xanthine dehydrogenase HQN80_RS17465 ENOG4107XAN XdhC and CoxI family HQN80_RS17480 ENOG4108NKV transcriptional regulator HQN80_RS17495 ENOG4105UZW Tail fiber assembly protein HQN80_RS17515 ENOG4105CAR Terminase, large subunit HQN80_RS17525 ENOG4108S1U HQN80_RS17550 ENOG4105H40 HQN80_RS17555 ENOG4108HJ1 Uncharacterized conserved protein (DUF2303) HQN80_RS17560 ENOG4108R7K Metal Dependent Phosphohydrolase HQN80_RS17570 ENOG4108R7K Metal Dependent Phosphohydrolase HQN80_RS17585 ENOG4108KU3 Integrase HQN80_RS17605 ENOG4105FCK Membrane HQN80_RS17625 ENOG4105CIN aminoacyl-histidine dipeptidase HQN80_RS17630 ENOG4108S2Y peptide Chain Release factor HQN80_RS17640 ENOG4108HYG acetyltransferase HQN80_RS17645 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) HQN80_RS17660 ENOG4108UK5 Transposase HQN80_RS17665 ENOG4108YS0 lipoprotein YafL HQN80_RS17670 ENOG4105F7V ErfK ybiS ycfS ynhG family protein HQN80_RS17675 ENOG4105E7A Glutamine amidotransferase HQN80_RS17685 ENOG4107QPN acyl-Coa dehydrogenase HQN80_RS17690 ENOG4108WN0 inhibitor of vertebrate lysozyme HQN80_RS17695 ENOG4105CZ7 nitrilase cyanide hydratase and apolipoprotein n-acyltransferase HQN80_RS17725 ENOG4105GMB type VI secretion system effector, hcp1 family HQN80_RS17740 ENOG410600K aminopeptidase HQN80_RS17750 ENOG4107RZZ dna polymerase iii epsilon subunit HQN80_RS17760 ENOG4105D1A Methyltransferase HQN80_RS17770 ENOG4105E9H Lytic Murein transglycosylase HQN80_RS17785 ENOG4105HEI LysR family (Transcriptional regulator HQN80_RS17790 ENOG4105CV8 reductase HQN80_RS17825 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase HQN80_RS17830 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) HQN80_RS17835 ENOG4108UMI ABC transporter, permease HQN80_RS17840 ENOG4105D01 (LipO)protein HQN80_RS17845 ENOG4108R8X outer membrane lipoprotein HQN80_RS17850 ENOG4108R96 Methyltransferase, YaeB family HQN80_RS17865 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion HQN80_RS17870 ENOG4108YZN class I peptide chain release factor HQN80_RS17875 ENOG4108VWS Yaeq family HQN80_RS17885 ENOG4105M1T rho-binding antiterminator HQN80_RS17890 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) HQN80_RS17895 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase HQN80_RS17900 ENOG4105CXN decarboxylase HQN80_RS17910 ENOG4105C0B DNA polymerase III (alpha subunit) HQN80_RS17935 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) HQN80_RS17940 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) HQN80_RS17950 ENOG4105DZP Membrane-associated zinc metalloprotease HQN80_RS17955 ENOG4105KNE Phosphatidate cytidylyltransferase HQN80_RS17960 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) HQN80_RS17965 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) HQN80_RS17990 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) HQN80_RS18010 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR HQN80_RS18015 ENOG4105C0H protease HQN80_RS18030 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) HQN80_RS18035 ENOG4105EN6 Membrane HQN80_RS18060 ENOG4105S6R Iron-hydroxamate transporter permease subunit HQN80_RS18065 ENOG4105J76 Periplasmic binding protein HQN80_RS18070 ENOG4105E0A ABC, transporter HQN80_RS18075 ENOG4105E0K tonB-dependent siderophore receptor HQN80_RS18080 ENOG4105BZ4 penicillin-binding protein HQN80_RS18085 ENOG4105CQ7 ATP-dependent helicase HQN80_RS18090 ENOG4107XID 2'-5' rna ligase HQN80_RS18110 ENOG4105DJ0 Poly(A) Polymerase HQN80_RS18115 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase HQN80_RS18125 ENOG4108VEV chaperone HQN80_RS18130 ENOG4105CW0 outer membrane usher protein HQN80_RS18135 ENOG4108XEY fimbrial-like adhesin protein HQN80_RS18140 ENOG4105SYG Fimbrial protein HQN80_RS18145 ENOG4105SN2 fimbrial-like adhesin protein HQN80_RS18180 ENOG4108A32 Transposase HQN80_RS18190 ENOG4107BJW polysaccharide deacetylase HQN80_RS18195 ENOG4108YTN IIa component HQN80_RS18200 ENOG4105E3A (ABC) transporter HQN80_RS18205 ENOG4105DA5 (ABC) transporter HQN80_RS18210 ENOG41077A9 carbonic anhydrase HQN80_RS18215 ENOG4108UGV hypoxanthine phosphoribosyltransferase HQN80_RS18220 ENOG4105DZG Dehydrogenase HQN80_RS18225 ENOG4105E3B Multicopper oxidase HQN80_RS18230 ENOG4108ZRK uncharacterized protein yacC HQN80_RS18250 ENOG4107QIJ Aconitate hydratase 2 HQN80_RS18255 ENOG4108NST exported protein HQN80_RS18260 ENOG4107QN2 dihydrolipoyl dehydrogenase HQN80_RS18265 ENOG4107QSN dihydrolipoamide acetyltransferase HQN80_RS18270 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) HQN80_RS18275 ENOG41073TP transcriptional regulator HQN80_RS18280 ENOG4105C85 amino acid HQN80_RS18285 ENOG4106A72 regulatory protein AmpE HQN80_RS18290 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase HQN80_RS18295 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase HQN80_RS18300 ENOG4108ZUW Major pilin subunit HQN80_RS18305 ENOG4107QHF type ii secretion system protein e HQN80_RS18310 ENOG4105D7Q type ii secretion system HQN80_RS18320 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) HQN80_RS18335 ENOG4105M6F mutator MutT protein HQN80_RS18345 ENOG4108SR7 Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation (By similarity) HQN80_RS18355 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) HQN80_RS18360 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) HQN80_RS18365 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) HQN80_RS18370 ENOG4105CPF Cell wall formation (By similarity) HQN80_RS18375 ENOG4105DFU Cell wall formation (By similarity) HQN80_RS18385 ENOG4105CNI cell division protein FtsW HQN80_RS18390 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) HQN80_RS18400 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) HQN80_RS18405 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) HQN80_RS18410 ENOG4105CJN penicillin-binding protein HQN80_RS18415 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) HQN80_RS18430 ENOG4107B7Y DNA-binding transcriptional regulator FruR HQN80_RS18440 ENOG4108ZP8 Acetolactate synthase small subunit HQN80_RS18445 ENOG4105C7K acetolactate synthase HQN80_RS18450 ENOG41064T2 transcriptional regulator, lysR family HQN80_RS18465 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) HQN80_RS18480 ENOG4105S8Q sugar efflux transporter HQN80_RS18495 ENOG4105DP9 ABC transporter HQN80_RS18500 ENOG4106SMU thiamine transporter membrane protein HQN80_RS18510 ENOG4108KF1 Membrane HQN80_RS18515 ENOG41063TF transcriptional regulator (AraC HQN80_RS18520 ENOG4105EF1 ribulokinase HQN80_RS18530 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase HQN80_RS18535 ENOG4105CQ2 DNA polymerase HQN80_RS18540 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) HQN80_RS18545 ENOG4105D3G Pseudouridine synthase HQN80_RS18550 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) HQN80_RS18555 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) HQN80_RS18560 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) HQN80_RS18580 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) HQN80_RS18585 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) HQN80_RS18600 ENOG4105C54 Major Facilitator superfamily HQN80_RS18605 ENOG4105IBM Could be part of an electron transfer system required for anaerobic carnitine reduction. Could be a 3Fe-4S cluster- containing protein HQN80_RS18610 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase HQN80_RS18615 ENOG4105C10 Electron transfer flavoprotein HQN80_RS18645 ENOG4106YT9 Enoyl-CoA hydratase HQN80_RS18655 ENOG4108XNW Transcriptional activatory protein CaiF HQN80_RS18660 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain HQN80_RS18665 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain HQN80_RS18685 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase HQN80_RS18695 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) HQN80_RS18700 ENOG4105DTN riboflavin biosynthesis protein ribF HQN80_RS18705 ENOG410647N response to DNA damage stimulus HQN80_RS18720 ENOG4105CW0 outer membrane usher protein HQN80_RS18725 ENOG4105CW0 outer membrane usher protein HQN80_RS18735 ENOG41063Z6 transcriptional regulator, lysR family HQN80_RS18745 ENOG4105WI6 cell killing protein encoded within cryptic prophage HQN80_RS18765 ENOG4108QUJ UPF0174 protein YaaW HQN80_RS18770 ENOG4106HK8 GPR1 FUN34 yaaH family protein HQN80_RS18775 ENOG4108RIR Molybdenum cofactor biosynthesis protein HQN80_RS18780 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) HQN80_RS18785 ENOG4105BZG amino acid carrier protein HQN80_RS18795 ENOG41062C6 Protein of unknown function (DUF2502) HQN80_RS18800 ENOG4105D98 threonine synthase HQN80_RS18810 ENOG4105CFH Aspartokinase HQN80_RS18820 ENOG4106FVC RNA methyltransferase HQN80_RS18825 ENOG410759A HQN80_RS18830 ENOG41065U4 response regulator HQN80_RS18835 ENOG4105CT7 inner membrane cred family protein HQN80_RS18845 ENOG4105E3W Two component transcriptional regulator (Winged helix family HQN80_RS18850 ENOG4108RH0 Crea protein HQN80_RS18855 ENOG4105UEI Transcriptional Regulator AraC Family HQN80_RS18875 ENOG4107SC1 transglycosylase HQN80_RS18880 ENOG4105C5H ABC transporter HQN80_RS18885 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase HQN80_RS18890 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) HQN80_RS18895 ENOG4105EAC phosphoserine phosphatase HQN80_RS18900 ENOG41062Z9 Membrane HQN80_RS18935 ENOG4105G0K glycine radical enzyme YjjI family HQN80_RS18940 ENOG41076CZ activating enzyme HQN80_RS18945 ENOG4105EYA deoxyribonuclease HQN80_RS18950 ENOG4108NRW Phospholipase, patatin family HQN80_RS18960 ENOG4105K3G Periplasmic Protein HQN80_RS18995 ENOG4105UZW Tail fiber assembly protein HQN80_RS19015 ENOG4105HGD Antitermination protein HQN80_RS19020 ENOG4108MXB Protein of unknown function (DUF968) HQN80_RS19030 ENOG4106CZA Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC (By similarity) HQN80_RS19060 ENOG4108S1U HQN80_RS19065 ENOG41078CG DNA-binding transcriptional regulator HQN80_RS19070 ENOG4105RDA repressor HQN80_RS19075 ENOG4105H40 HQN80_RS19080 ENOG4108HJ1 Uncharacterized conserved protein (DUF2303) HQN80_RS19085 ENOG4108R7K Metal Dependent Phosphohydrolase HQN80_RS19090 ENOG41077V0 CPS-53 (KpLE1) prophage HQN80_RS19110 ENOG4105PAD Hydrolase HQN80_RS19115 ENOG4105KEG ribosomal-protein-alanine acetyltransferase HQN80_RS19120 ENOG4108WPU DNA polymerase III subunit psi HQN80_RS19145 ENOG4105YBH Protein of unknown function (DUF1435) HQN80_RS19150 ENOG4108819 ferric iron reductase HQN80_RS19155 ENOG4108T94 DNA-binding transcriptional activator BglJ HQN80_RS19160 ENOG4108N8T regulatoR HQN80_RS19165 ENOG4105DWK Membrane HQN80_RS19170 ENOG4107XM3 UPF0442 protein HQN80_RS19180 ENOG4106CVF DNA replication protein HQN80_RS19185 ENOG4105RI1 glycoprotein receptor HQN80_RS19195 ENOG4105CPQ Dehydrogenase HQN80_RS19200 ENOG410617M Transcriptional regulator HQN80_RS19210 ENOG4108I5G Major Facilitator superfamily HQN80_RS19215 ENOG4105C8Q Methyl-accepting chemotaxis HQN80_RS19220 ENOG4108V8F Transcriptional regulator, MarR family HQN80_RS19225 ENOG4105ERH Fumarylacetoacetate hydrolase HQN80_RS19230 ENOG4105C26 Dehydrogenase HQN80_RS19235 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase HQN80_RS19250 ENOG4105CNV Aldolase HQN80_RS19265 ENOG4105EFA 4-hydroxyphenylacetate HQN80_RS19270 ENOG4107UWN reductase HQN80_RS19275 ENOG4105D22 carbon starvation protein HQN80_RS19280 ENOG4105VCD cytoplasmic protein HQN80_RS19285 ENOG4105CKI cobalamin synthesis protein HQN80_RS19295 ENOG4106DIZ Domain of unknown function (DUF1127) HQN80_RS19300 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family HQN80_RS19310 ENOG41083G8 Multidrug resistance protein MdtM HQN80_RS19315 ENOG4106BRA Membrane HQN80_RS19320 ENOG4105DCU 2-hydroxyglutaryl-CoA dehydratase HQN80_RS19325 ENOG4105CIZ coA-substrate-specific enzyme activase HQN80_RS19340 ENOG4105CBP Major Facilitator HQN80_RS19350 ENOG41074DU domain protein HQN80_RS19355 ENOG4108P2H Inner membrane protein YjiG HQN80_RS19360 ENOG4105DYB Isoaspartyl dipeptidase HQN80_RS19365 ENOG4107YNJ LysR family Transcriptional regulator HQN80_RS19385 ENOG4105C6F GntR Family Transcriptional Regulator HQN80_RS19390 ENOG4105DEI Mannitol dehydrogenase HQN80_RS19405 ENOG410643X FIMH SUBUNIT MANNOSE-sensitive type 1 fimbrial adhesin HQN80_RS19410 ENOG4108T65 Fimbrial HQN80_RS19415 ENOG4108SQA Fimbrial HQN80_RS19420 ENOG4105CW0 outer membrane usher protein HQN80_RS19425 ENOG4108NAE Fimbrial chaperone protein HQN80_RS19430 ENOG4108S54 Fimbrial protein HQN80_RS19440 ENOG4105E71 FimE is one of the 2 regulatory proteins which control the phase variation of type 1 fimbriae in E.coli. These proteins mediate the periodic inversion of a 300bp DNA segment that harbors the promoter for the fimbrial structural gene, fimA. FimE switches fimA off HQN80_RS19445 ENOG4108W9T type 1 fimbriae regulatory protein HQN80_RS19455 ENOG4108MX5 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity) HQN80_RS19505 ENOG4108YXQ IS66 Orf2 family protein HQN80_RS19510 ENOG4105E5H Transposase HQN80_RS19545 ENOG4108SF5 RNA Polymerase HQN80_RS19550 ENOG4108S3W Anti-feci sigma factor, fecr HQN80_RS19555 ENOG4105GAV receptor HQN80_RS19560 ENOG4108HUF Transporter HQN80_RS19565 ENOG4105DQ5 transport system permease protein HQN80_RS19570 ENOG4108IHU transport system permease protein HQN80_RS19575 ENOG4105E0A ABC, transporter HQN80_RS19590 ENOG4105F9F transposase HQN80_RS19595 ENOG4105PBD transposase, IS3 IS911 family protein HQN80_RS19650 ENOG4105DQ4 alcohol dehydrogenase HQN80_RS19655 ENOG4105D7A ATP-binding protein HQN80_RS19660 ENOG4108K5H permease YjgP YjgQ family protein HQN80_RS19665 ENOG4108M8S permease YjgP YjgQ family protein HQN80_RS19675 ENOG4105MYG DNA polymerase iii, chi subunit HQN80_RS19680 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) HQN80_RS19685 ENOG4108M3P Membrane HQN80_RS19690 ENOG4108MJ3 acetyltransferase HQN80_RS19695 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) HQN80_RS19710 ENOG4105XEP YhcH YjgK YiaL family protein HQN80_RS19715 ENOG4108XFH Transcriptional regulator HQN80_RS19720 ENOG4105F6U Short-chain dehydrogenase reductase Sdr HQN80_RS19725 ENOG4108UQ8 endoribonuclease L-psp HQN80_RS19730 ENOG4107C93 pyrBI operon leader peptide HQN80_RS19745 ENOG4105KME endoribonuclease L-psp HQN80_RS19750 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic HQN80_RS19760 ENOG4105D4X repressor HQN80_RS19765 ENOG4105C5Y PTS System HQN80_RS19770 ENOG4105CG3 alpha amylase, catalytic region HQN80_RS19775 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase HQN80_RS19780 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) HQN80_RS19790 ENOG4105CMS peptidase U62, modulator of DNA gyrase HQN80_RS19800 ENOG4105DFU Cell wall formation (By similarity) HQN80_RS19810 ENOG41062B0 ABC transporter, permease HQN80_RS19815 ENOG4107R9N ABC transporter HQN80_RS19820 ENOG4105C2J ABC transporter HQN80_RS19825 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator HQN80_RS19830 ENOG4105F0N pyrophosphate phospho-hydrolase HQN80_RS19835 ENOG4108ZHD aig2 family HQN80_RS19840 ENOG4105MA0 exported protein HQN80_RS19845 ENOG4105CFU surface antigen HQN80_RS19855 ENOG4105C37 (CBS) domain HQN80_RS19860 ENOG41061GZ Protein of unknown function (DUF1107) HQN80_RS19865 ENOG4108UUE Transcriptional regulator HQN80_RS19870 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase HQN80_RS19875 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic HQN80_RS19880 ENOG4105KVH Transcriptional regulator HQN80_RS19885 ENOG4105ECR NmrA family HQN80_RS19890 ENOG4105DXC membrane HQN80_RS19900 ENOG4105C85 amino acid HQN80_RS19905 ENOG4108V1T peptidylprolyl cis-trans isomerase HQN80_RS19910 ENOG4105FHY Opacity-associated protein A HQN80_RS19920 ENOG4105CHR reductase HQN80_RS19930 ENOG4105E39 Enoyl-CoA hydratase HQN80_RS19935 ENOG4107R0K CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) HQN80_RS19940 ENOG4107S3R L-aspartate oxidase HQN80_RS19945 ENOG41069H7 transport system small permease component HQN80_RS19950 ENOG4105CG6 trap dicarboxylate transporter dctm subunit HQN80_RS19955 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit HQN80_RS19965 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) HQN80_RS19980 ENOG4105KIT UPF0379 protein yjfY HQN80_RS19985 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase HQN80_RS20005 ENOG410907W The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in ascorbate transport HQN80_RS20010 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC HQN80_RS20025 ENOG4108MXZ Esterase HQN80_RS20030 ENOG4105WSB biofilm stress and motility protein A HQN80_RS20035 ENOG4105S17 UPF0379 protein yjfN HQN80_RS20040 ENOG4105CSU acyl-Coa dehydrogenase HQN80_RS20045 ENOG4106032 Glutathionylspermidine synthase HQN80_RS20050 ENOG4108KXT Conserved Protein HQN80_RS20055 ENOG4105Z6B inner membrane protein yjfl HQN80_RS20060 ENOG4107VNS Protein of unknown function (DUF2491) HQN80_RS20065 ENOG4108P9J Phage shock protein A HQN80_RS20070 ENOG4105FUX Conserved Protein HQN80_RS20075 ENOG4105C2N RNA methyltransferase TrmH family group 3 HQN80_RS20080 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) HQN80_RS20100 ENOG4105EPW hflc protein HQN80_RS20105 ENOG4107QJR hflk protein HQN80_RS20110 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) HQN80_RS20125 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) HQN80_RS20130 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase HQN80_RS20135 ENOG4105K8N protein family UPF0079, ATPase HQN80_RS20140 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) HQN80_RS20145 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) HQN80_RS20185 ENOG4105EGS Mechanosensitive ion channel HQN80_RS20190 ENOG4106CG8 Inner membrane protein YjeO HQN80_RS20195 ENOG4106V5W HQN80_RS20200 ENOG4107SC7 Inner membrane transporter yjeM HQN80_RS20210 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) HQN80_RS20215 ENOG4105E33 succinate dehydrogenase HQN80_RS20230 ENOG41066YJ Beta-lactamase HQN80_RS20235 ENOG4105QNF Outer membrane lipoprotein HQN80_RS20240 ENOG4105KPY Small multidrug resistance protein HQN80_RS20245 ENOG4106BSU Entericidin B HQN80_RS20250 ENOG4107PEH Entericidin EcnA/B family HQN80_RS20260 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein HQN80_RS20265 ENOG4105MTB Uncharacterized protein YjeJ HQN80_RS20270 ENOG4108ZVF (LipO)protein HQN80_RS20285 ENOG4105DVH amino acid HQN80_RS20290 ENOG4108YH1 overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7 HQN80_RS20295 ENOG4108IJ0 Aspartate ammonia-lyase HQN80_RS20300 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter HQN80_RS20315 ENOG4108SIC Transcriptional regulator HQN80_RS20325 ENOG4108M3R transcriptional activator CadC HQN80_RS20330 ENOG4105D5Q Arginine ornithine antiporter HQN80_RS20335 ENOG4105CXN decarboxylase HQN80_RS20340 ENOG4105DUX Transporter HQN80_RS20345 ENOG4105CRK lysyL-tRNA synthetase HQN80_RS20360 ENOG410830R acetyltransferase HQN80_RS20365 ENOG4105VR1 Pfam:DUF1271 HQN80_RS20370 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism HQN80_RS20375 ENOG4108MRH transcriptional regulatory protein HQN80_RS20380 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter HQN80_RS20385 ENOG4107GFK fumarate HQN80_RS20390 ENOG4108R5S membrane HQN80_RS20400 ENOG4105F8D glycoside hydrolase family 4 HQN80_RS20405 ENOG4108K2B transcriptional regulator HQN80_RS20410 ENOG4105CXN decarboxylase HQN80_RS20415 ENOG4106ZGR Transcriptional regulator HQN80_RS20420 ENOG4105D5Q Arginine ornithine antiporter HQN80_RS20425 ENOG4105DIJ Phosphoethanolamine transferase HQN80_RS20430 ENOG4105XJC Two component transcriptional regulator (Winged helix family HQN80_RS20435 ENOG4105ECM Sensor protein basS pmrB HQN80_RS20445 ENOG4105CSH Transporter HQN80_RS20450 ENOG4108YIV HQN80_RS20455 ENOG4108F5E vimentin HQN80_RS20460 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA HQN80_RS20465 ENOG4108SQ4 Glyoxalase Bleomycin resistance protein (Dioxygenase HQN80_RS20470 ENOG4105D5T phosphonate abc transporter HQN80_RS20475 ENOG4105EHI Phosphonate ABC transporter, periplasmic HQN80_RS20485 ENOG4107RJJ Transcriptional regulator HQN80_RS20490 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG HQN80_RS20495 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH HQN80_RS20500 ENOG4105EKV Phosphonate metabolism protein HQN80_RS20505 ENOG4105FT8 Phosphonate metabolism HQN80_RS20510 ENOG4105ENV phosphonate C-P lyase system protein PhnK HQN80_RS20515 ENOG4105HRV phosphonate c-p lyase system protein phnl HQN80_RS20520 ENOG4105FD8 phosphonate metabolism protein PhnM HQN80_RS20525 ENOG4105MFQ Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity) HQN80_RS20530 ENOG410849A acetyltransferase, (GNAT) family HQN80_RS20535 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein HQN80_RS20545 ENOG4108YZG isomerase HQN80_RS20550 ENOG4105NYY transcriptional regulator, RpiR HQN80_RS20555 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator HQN80_RS20560 ENOG4105C2J ABC transporter HQN80_RS20565 ENOG4105CNN ABC, transporter HQN80_RS20570 ENOG4105UP7 3-epimerase HQN80_RS20575 ENOG4107TFG D-allose kinase HQN80_RS20580 ENOG4105EUZ Beta-lactamase domain protein HQN80_RS20590 ENOG4105J12 Multidrug resistance protein mdtN HQN80_RS20595 ENOG4108MI0 Resistance protein HQN80_RS20600 ENOG4105ETP RND efflux system, outer membrane lipoprotein HQN80_RS20610 ENOG41082ND Uncharacterized protein yjcO HQN80_RS20615 ENOG4105CK2 sodium dicarboxylate symporter HQN80_RS20620 ENOG4108W0S formate-dependent nitrite reductase complex HQN80_RS20630 ENOG4108QKW cytochrome c-type biogenesis protein HQN80_RS20635 ENOG4105DVI reductase, NrfD HQN80_RS20640 ENOG4105D3S 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HQN80_RS20645 ENOG4105JJ8 Cytochrome c nitrite reductase, pentaheme subunit HQN80_RS20655 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) HQN80_RS20660 ENOG41062QD Membrane HQN80_RS20675 ENOG4105EEQ Na H antiporter HQN80_RS20680 ENOG4105C7N Xanthine uracil vitamin C permease HQN80_RS20685 ENOG4108Z4X TRANSCRIPTIONal HQN80_RS20690 ENOG4108W3Q Transcriptional regulator HQN80_RS20710 ENOG4105PMV Membrane HQN80_RS20715 ENOG4108UUM single-stranded DNA-binding protein HQN80_RS20720 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) HQN80_RS20725 ENOG4105MSB protein, conserved in bacteria HQN80_RS20730 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme HQN80_RS20735 ENOG4105F0S class B acid phosphatase HQN80_RS20745 ENOG4105CGF Aromatic amino acid aminotransferase HQN80_RS20750 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) HQN80_RS20755 ENOG4105CDU Replicative dna helicase HQN80_RS20760 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein HQN80_RS20765 ENOG4105P4Z Phage shock protein G HQN80_RS20770 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) HQN80_RS20780 ENOG4106FE3 DNA repair HQN80_RS20815 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 HQN80_RS20820 ENOG4105KUS lysozyme HQN80_RS20825 ENOG4105QFS Lysis protein S homolog from lambdoid prophage HQN80_RS20855 ENOG4108MXB Protein of unknown function (DUF968) HQN80_RS20865 ENOG4106CZA Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC (By similarity) HQN80_RS20910 ENOG41078CG DNA-binding transcriptional regulator HQN80_RS20915 ENOG4105RDA repressor HQN80_RS20920 ENOG4105H40 HQN80_RS20925 ENOG4108HJ1 Uncharacterized conserved protein (DUF2303) HQN80_RS20950 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) HQN80_RS20960 ENOG4105MYN Zinc uptake regulation protein HQN80_RS20965 ENOG4105VDW Csbd family HQN80_RS20970 ENOG4107R73 Mate efflux family protein HQN80_RS20980 ENOG41080IJ Diacylglycerol kinase HQN80_RS21005 ENOG4107W52 maltose operon periplasmic protein HQN80_RS21015 ENOG4108IJ9 (ABC) transporter HQN80_RS21020 ENOG4107FKK extracellular solute-binding protein family 1 HQN80_RS21025 ENOG4105D56 permease protein HQN80_RS21030 ENOG4105EG2 ABC transporter, permease HQN80_RS21035 ENOG4107QNK )-transporter HQN80_RS21055 ENOG4105E3R (LipO)protein HQN80_RS21075 ENOG4108MDC (LipO)protein HQN80_RS21085 ENOG4107QP8 phosphohexose isomerase HQN80_RS21090 ENOG4105CFH Aspartokinase HQN80_RS21095 ENOG4108WZA zeta toxin HQN80_RS21100 ENOG410756H nucleotidyltransferase HQN80_RS21110 ENOG4108ZR5 Conserved Protein HQN80_RS21115 ENOG4105FE9 pseudouridine synthase HQN80_RS21120 ENOG4105DKT Transcriptional regulator HQN80_RS21125 ENOG4105CHR reductase HQN80_RS21130 ENOG4108XCU pts system HQN80_RS21135 ENOG4105KPI PTS system sorbose subfamily IIB component HQN80_RS21140 ENOG4105ETZ PTS System HQN80_RS21145 ENOG4105F3R pts system mannose fructose sorbose family iid HQN80_RS21150 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein HQN80_RS21160 ENOG4105EAM Na Pi-cotransporter HQN80_RS21165 ENOG4105C3R Methionine synthase HQN80_RS21170 ENOG41069M3 Transcriptional regulator HQN80_RS21185 ENOG4108I9X Isocitrate lyase HQN80_RS21190 ENOG4107QP3 malate synthase g HQN80_RS21200 ENOG4105K5X acetyltransferase HQN80_RS21205 ENOG41062WK cellular response to acidity HQN80_RS21235 ENOG4105C12 Phosphoribosylglycinamide synthetase HQN80_RS21240 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HQN80_RS21245 ENOG4105BZU Histidine kinase HQN80_RS21250 ENOG4105JBU Binds zinc. Could be an important component of the zinc- balancing mechanism HQN80_RS21255 ENOG4108T8B Protein of unknown function (DUF1481) HQN80_RS21265 ENOG4105R2J Conserved Protein HQN80_RS21300 ENOG4105D06 uba thif-type nad fad binding protein HQN80_RS21305 ENOG4105WHD thiamine biosynthesis protein ThiS HQN80_RS21315 ENOG4105D41 biosynthesis protein thiH HQN80_RS21320 ENOG410645W Thiamin biosynthesis protein ThiH HQN80_RS21355 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) HQN80_RS21360 ENOG4105PM1 preprotein translocase subunit SecE HQN80_RS21395 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase HQN80_RS21440 ENOG4108Y73 Membrane HQN80_RS21445 ENOG4105EJ2 Transcriptional regulator HQN80_RS21455 ENOG4105C5Q Transcriptional regulator HQN80_RS21460 ENOG4108I5G Major Facilitator superfamily HQN80_RS21465 ENOG4105CXK mandelate racemase muconate lactonizing HQN80_RS21480 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase HQN80_RS21495 ENOG4105DIJ Phosphoethanolamine transferase HQN80_RS21500 ENOG4106R3P AraC family transcriptional regulator HQN80_RS21505 ENOG4108XCZ PTS System HQN80_RS21510 ENOG4108AHH pyruvate formate lyase II activase HQN80_RS21520 ENOG4108YRF PTS System HQN80_RS21525 ENOG4105DM4 PTS System HQN80_RS21530 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) HQN80_RS21535 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) HQN80_RS21540 ENOG4105DCT glycerol dehydrogenase HQN80_RS21545 ENOG4108XC3 NADH ubiquinone oxidoreductase HQN80_RS21550 ENOG4108Q5Y Membrane HQN80_RS21560 ENOG4105SYT Methylenetetrahydrofolate reductase HQN80_RS21565 ENOG4105CFH Aspartokinase HQN80_RS21570 ENOG4105C28 cystathionine HQN80_RS21580 ENOG4107S01 Repressor protein MetJ HQN80_RS21605 ENOG4105CNA YD repeat protein HQN80_RS21615 ENOG4105C25 Primosomal protein n' HQN80_RS21620 ENOG4105ETE Transcriptional regulator (LacI family HQN80_RS21625 ENOG41063M6 Cell Division Protein HQN80_RS21640 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase HQN80_RS21655 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) HQN80_RS21665 ENOG4105CBT Fructose-1,6-bisphosphatase HQN80_RS21670 ENOG4105DP0 ferredoxin-NADP reductase HQN80_RS21680 ENOG41065TG regulatoR HQN80_RS21685 ENOG4108VTS Membrane HQN80_RS21690 ENOG4105EBK exported protein HQN80_RS21705 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein HQN80_RS21720 ENOG4105FMW periplasmic HQN80_RS21725 ENOG4105E3W Two component transcriptional regulator (Winged helix family HQN80_RS21730 ENOG4105E0F Histidine kinase HQN80_RS21735 ENOG4108RPX mosc domain containing protein HQN80_RS21745 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) HQN80_RS21775 ENOG4105C9J Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde (By similarity) HQN80_RS21785 ENOG41064BA PTS system, fructose-specific, IIA component HQN80_RS21790 ENOG4105DM4 PTS System HQN80_RS21795 ENOG4105CN9 Peptidase m42 family protein HQN80_RS21800 ENOG4106C3V frv operon regulatory protein HQN80_RS21820 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) HQN80_RS21830 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HQN80_RS21835 ENOG4108MG3 formate dehydrogenase HQN80_RS21845 ENOG41068KX affects formate dehydrogenase-N HQN80_RS21855 ENOG4105SUU thioesterase domain HQN80_RS21870 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 HQN80_RS21875 ENOG4105E98 transcriptional regulator DeoR family HQN80_RS21880 ENOG4108MGF sugar kinase HQN80_RS21885 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase HQN80_RS21890 ENOG4105D2M Aldolase HQN80_RS21895 ENOG4107QKS N-acylglucosamine 2-epimerase HQN80_RS21900 ENOG4107WI4 Aldose-1-epimerase HQN80_RS21905 ENOG4105CJQ hydrolase, family 31 HQN80_RS21910 ENOG4105CT4 transporter HQN80_RS21915 ENOG4105CT4 transporter HQN80_RS21920 ENOG4108KUC Outer membrane channel protein that allows an efficient diffusion of low-molecular-weight solutes such as small sugars and tetraglycine. However, the specific substrate recognized by the OmpL channel is HQN80_RS21925 ENOG4105R9B Major Facilitator HQN80_RS21930 ENOG4108KHF Resistance protein HQN80_RS21935 ENOG4108K85 Transcriptional regulator HQN80_RS21940 ENOG4105CI3 gtp-binding protein typa HQN80_RS21945 ENOG4105C5F glutamine synthetase HQN80_RS21950 ENOG4105CUX Signal transduction histidine kinase HQN80_RS21955 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HQN80_RS21960 ENOG4106FIY HQN80_RS21965 ENOG4105D4P Coproporphyrinogen iii oxidase HQN80_RS21980 ENOG4105C2M dna polymerase I HQN80_RS21985 ENOG4106HNH Acyl-transferase HQN80_RS21995 ENOG4108Z33 Thiol disulfide Interchange Protein HQN80_RS22000 ENOG4105E27 serine threonine protein kinase HQN80_RS22005 ENOG4105PC1 Conserved Protein HQN80_RS22010 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) HQN80_RS22015 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b HQN80_RS22045 ENOG4108RR8 protoporphyrinogen oxidase HQN80_RS22050 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) HQN80_RS22055 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein HQN80_RS22065 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase HQN80_RS22075 ENOG4108EX3 reductase HQN80_RS22080 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) HQN80_RS22085 ENOG4105MDZ Transcriptional activator rfaH HQN80_RS22095 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) HQN80_RS22100 ENOG4105X8U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity) HQN80_RS22105 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) HQN80_RS22115 ENOG4105JC1 sterol-binding domain protein HQN80_RS22125 ENOG4105CGY Dna recombination protein HQN80_RS22130 ENOG4108I5U Uridine phosphorylase HQN80_RS22135 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) HQN80_RS22145 ENOG4105DZ2 Transcriptional regulator HQN80_RS22150 ENOG4105EMK carboxylate amino acid amine transporter HQN80_RS22155 ENOG4105DQF Hydrolase HQN80_RS22160 ENOG4108EUD Lysophospholipase HQN80_RS22165 ENOG410829K Lysine exporter protein (Lyse ygga) HQN80_RS22170 ENOG4105CCF Lysine exporter protein (Lyse ygga) HQN80_RS22175 ENOG4105C9U ATP-dependent DNA helicase RecQ HQN80_RS22180 ENOG4105HDD phospholipase HQN80_RS22185 ENOG4108VUY thioesterase Superfamily protein HQN80_RS22190 ENOG4105FR1 rard protein HQN80_RS22195 ENOG4106WR8 Inner membrane protein YigG HQN80_RS22200 ENOG4105NRM Membrane HQN80_RS22205 ENOG4107QUT magnesium and cobalt transport protein CorA HQN80_RS22210 ENOG4108T58 Mg2 transport protein CorA HQN80_RS22215 ENOG4105C4R Atp-dependent dna helicase HQN80_RS22220 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant HQN80_RS22230 ENOG4105CT0 Protein of unknown function, DUF484 HQN80_RS22240 ENOG4105S7Z (LipO)protein HQN80_RS22250 ENOG4107T0K Adenylate cyclase HQN80_RS22255 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) HQN80_RS22260 ENOG41076E6 Uroporphyrinogen-III Synthase HQN80_RS22265 ENOG4105ECF c-methyltransferase HQN80_RS22270 ENOG410601J HemY protein HQN80_RS22275 ENOG4105ENH Sulfatase HQN80_RS22280 ENOG4105C4X radical SAM domain protein HQN80_RS22305 ENOG4105C85 amino acid HQN80_RS22325 ENOG4105EGZ biosynthesis protein HQN80_RS22330 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase HQN80_RS22335 ENOG4108WJ1 acetyltransferase HQN80_RS22340 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) HQN80_RS22345 ENOG4105C1B dTDP-glucose 4-6-dehydratase HQN80_RS22350 ENOG4107QQG Dehydrogenase HQN80_RS22355 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase HQN80_RS22360 ENOG4105SFE lipopolysaccharide biosynthesis protein HQN80_RS22365 ENOG4105ESV Glycosyl transferase, family 4 HQN80_RS22370 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) HQN80_RS22395 ENOG4105C4R Atp-dependent dna helicase HQN80_RS22405 ENOG4105KQ5 peptidylprolyl cis-trans isomerase HQN80_RS22415 ENOG4105EMY transcriptional regulator HQN80_RS22420 ENOG4105C7B Threonine dehydratase HQN80_RS22430 ENOG4105CM2 brancheD-chain amino acid aminotransferase HQN80_RS22435 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit HQN80_RS22455 ENOG4105C0P Mg chelatase subunit ChlI HQN80_RS22460 ENOG4108WFC UPF0438 protein yifE HQN80_RS22500 ENOG4107EJG GntR family transcriptional regulator HQN80_RS22505 ENOG4105C0R drug resistance transporter emrb qaca subfamily HQN80_RS22510 ENOG4105ETE Transcriptional regulator (LacI family HQN80_RS22515 ENOG4108RVA ribokinase HQN80_RS22520 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator HQN80_RS22525 ENOG4105CNN ABC, transporter HQN80_RS22550 ENOG4105EV2 VWA domain protein interacting with AAA ATPase HQN80_RS22560 ENOG4108VVK transcriptional Regulator, AsnC HQN80_RS22565 ENOG4105QTB Flavodoxin HQN80_RS22580 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation HQN80_RS22630 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) HQN80_RS22635 ENOG4108RQP Major type 1 subunit fimbrin HQN80_RS22665 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) HQN80_RS22670 ENOG4105C8U phosphate abc transporter HQN80_RS22675 ENOG4105E2Z phosphate ABC transporter (Permease HQN80_RS22680 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) HQN80_RS22685 ENOG4108UTW Plays a role in the regulation of phosphate uptake HQN80_RS22690 ENOG4105CID antiterminator HQN80_RS22695 ENOG4105C5Y PTS System HQN80_RS22700 ENOG4105CS2 ec 3.2.1.21 HQN80_RS22710 ENOG4105DYC esterase HQN80_RS22715 ENOG4107VKM 6-phosphogluconolactonase HQN80_RS22720 ENOG4106611 bacteriocin immunity HQN80_RS22730 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 HQN80_RS22735 ENOG4105C7N Xanthine uracil vitamin C permease HQN80_RS22740 ENOG4108YYH Nadph-dependent fmn reductase HQN80_RS22745 ENOG4105E8Q phosphopantetheinyl transferase HQN80_RS22755 ENOG4105CNH Multidrug resistance protein MdtL HQN80_RS22760 ENOG4108P6C Tryptophan transporter of low affinity HQN80_RS22795 ENOG4105VG0 50S ribosomal protein l34 HQN80_RS22815 ENOG410607W Transposase HQN80_RS22855 ENOG4108BUD transposase HQN80_RS22875 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) HQN80_RS23040 ENOG41073YN Protein of unknown function (DUF1380) HQN80_RS23290 ENOG4105CZX twitching motility protein HQN80_RS23355 ENOG4105K5T PilT protein HQN80_RS23370 ENOG4107QHF type ii secretion system protein e