locus-tag	class	description
AYN27_RS00005	COG0410	ABC transporter
AYN27_RS00010	COG1653	transport
AYN27_RS00015	COG1175	transmembrane transport
AYN27_RS00025	COG3842	ATPase activity
AYN27_RS00030	COG0584	glycerophosphoryl diester phosphodiesterase
AYN27_RS00040	COG0405	Gamma-glutamyltransferase
AYN27_RS00055	COG3157	Type VI secretion system effector, Hcp
AYN27_RS00060	COG1247	-acetyltransferase
AYN27_RS00070	COG0673	inositol 2-dehydrogenase activity
AYN27_RS00075	COG1741	Belongs to the pirin family
AYN27_RS00080	COG1609	Transcriptional regulator
AYN27_RS00085	COG3265	gluconokinase activity
AYN27_RS00090	COG2610	gluconate transmembrane transporter activity
AYN27_RS00095	COG2095	MarC family integral membrane protein
AYN27_RS00100	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AYN27_RS00125	COG0058	SHG alpha-glucan phosphorylase activity
AYN27_RS00130	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AYN27_RS00150	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AYN27_RS00165	COG1349	DNA-binding transcription factor activity
AYN27_RS00170	COG4650	regulator
AYN27_RS00175	COG1690	Belongs to the RtcB family
AYN27_RS00190	COG0058	SHG alpha-glucan phosphorylase activity
AYN27_RS00195	COG1640	4-alpha-glucanotransferase
AYN27_RS00200	COG2610	gluconate transmembrane transporter activity
AYN27_RS00220	COG5464	transposase or invertase
AYN27_RS00235	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AYN27_RS00240	COG1918	ferrous iron import across plasma membrane
AYN27_RS00250	COG2183	response to ionizing radiation
AYN27_RS00255	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AYN27_RS00280	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AYN27_RS00290	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AYN27_RS00295	COG1011	Hydrolase
AYN27_RS00305	COG0494	nUDIX hydrolase
AYN27_RS00310	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AYN27_RS00315	COG4972	Pilus assembly protein
AYN27_RS00320	COG3166	PFAM Fimbrial assembly family protein
AYN27_RS00335	COG4796	Type ii and iii secretion system protein
AYN27_RS00355	COG3266	domain, Protein
AYN27_RS00360	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AYN27_RS00365	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AYN27_RS00370	COG0546	phosphoglycolate phosphatase activity
AYN27_RS00375	COG0180	Tryptophanyl-tRNA synthetase
AYN27_RS00380	COG2188	Transcriptional regulator
AYN27_RS00390	COG3457	Alanine racemase
AYN27_RS00395	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AYN27_RS00400	COG1735	metal-dependent hydrolase with the TIM-barrel fold
AYN27_RS00415	COG0626	cystathionine gamma-synthase activity
AYN27_RS00420	COG2188	Transcriptional regulator
AYN27_RS00430	COG1082	Xylose isomerase domain protein TIM barrel
AYN27_RS00440	COG2222	sugar isomerase
AYN27_RS00445	COG0531	amino acid
AYN27_RS00460	COG2116	formate transmembrane transporter activity
AYN27_RS00465	COG2146	nitrite reductase [NAD(P)H] activity
AYN27_RS00470	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AYN27_RS00480	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AYN27_RS00490	COG2184	nucleotidyltransferase activity
AYN27_RS00495	COG0512	Glutamine amidotransferase of anthranilate synthase
AYN27_RS00500	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AYN27_RS00505	COG1289	transmembrane transporter activity
AYN27_RS00510	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AYN27_RS00520	COG1765	OsmC-like protein
AYN27_RS00525	COG3954	Phosphoribulokinase
AYN27_RS00535	COG0429	hydrolase of the alpha beta-hydrolase fold
AYN27_RS00540	COG0488	(ABC) transporter
AYN27_RS00560	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AYN27_RS00565	COG1047	Peptidyl-prolyl cis-trans
AYN27_RS00575	COG0545	Peptidyl-prolyl cis-trans isomerase
AYN27_RS00580	COG2964	Protein conserved in bacteria
AYN27_RS00660	COG0089	rRNA binding
AYN27_RS00750	COG0201	protein transport
AYN27_RS00790	COG0789	Transcriptional regulator
AYN27_RS00795	COG3036	rescue of stalled ribosome
AYN27_RS00805	COG0569	domain protein
AYN27_RS00835	COG0551	DNA topoisomerase type I activity
AYN27_RS00855	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AYN27_RS00900	COG1126	abc transporter atp-binding protein
AYN27_RS00905	COG0765	amino acid transport
AYN27_RS00910	COG4597	amino acid ABC transporter
AYN27_RS00915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AYN27_RS00930	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AYN27_RS00935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYN27_RS00945	COG1309	transcriptional regulator
AYN27_RS00955	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AYN27_RS00965	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AYN27_RS00975	COG4145	pantothenate transmembrane transporter activity
AYN27_RS00980	COG3924	membrane
AYN27_RS00985	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AYN27_RS00990	COG1349	DNA-binding transcription factor activity
AYN27_RS01000	COG1879	ABC-type sugar transport system periplasmic component
AYN27_RS01005	COG1129	ABC transporter
AYN27_RS01010	COG1172	Belongs to the binding-protein-dependent transport system permease family
AYN27_RS01015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AYN27_RS01025	COG0439	Biotin carboxylase
AYN27_RS01030	COG0511	ligase activity, forming carbon-carbon bonds
AYN27_RS01045	COG0604	alcohol dehydrogenase
AYN27_RS01050	COG2199	diguanylate cyclase activity
AYN27_RS01050	COG2200	EAL domain
AYN27_RS01065	COG1077	Cell shape determining protein MreB Mrl
AYN27_RS01070	COG1792	Involved in formation and maintenance of cell shape
AYN27_RS01075	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AYN27_RS01085	COG1530	ribonuclease E activity
AYN27_RS01090	COG3164	Protein of unknown function
AYN27_RS01095	COG0312	modulator of DNA gyrase
AYN27_RS01100	COG0583	DNA-binding transcription factor activity
AYN27_RS01120	COG2732	(Barnase) inhibitor
AYN27_RS01140	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AYN27_RS01145	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AYN27_RS01150	COG3105	Protein conserved in bacteria
AYN27_RS01155	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AYN27_RS01185	COG0625	glutathione transferase activity
AYN27_RS01190	COG2969	positive regulation of protein catabolic process
AYN27_RS01195	COG3069	C4-dicarboxylate transmembrane transporter activity
AYN27_RS01230	COG2731	YhcH YjgK YiaL family protein
AYN27_RS01240	COG0493	'glutamate synthase
AYN27_RS01245	COG0069	glutamate synthase activity
AYN27_RS01245	COG0070	glutamate synthase
AYN27_RS01245	COG0067	glutamate synthase
AYN27_RS01260	COG1242	4 iron, 4 sulfur cluster binding
AYN27_RS01265	COG0784	Response regulator, receiver
AYN27_RS01265	COG2198	Histidine kinase
AYN27_RS01265	COG5002	protein histidine kinase activity
AYN27_RS01270	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AYN27_RS01280	COG0515	serine threonine protein kinase
AYN27_RS01285	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN27_RS01300	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AYN27_RS01305	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AYN27_RS01310	COG1137	ATPase activity
AYN27_RS01315	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AYN27_RS01320	COG3117	lipopolysaccharide transmembrane transporter activity
AYN27_RS01325	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AYN27_RS01330	COG0517	IMP dehydrogenase activity
AYN27_RS01330	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AYN27_RS01335	COG0530	calcium, potassium:sodium antiporter activity
AYN27_RS01340	COG1127	ABC transporter
AYN27_RS01345	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AYN27_RS01350	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AYN27_RS01355	COG2854	intermembrane phospholipid transfer
AYN27_RS01360	COG3113	response to antibiotic
AYN27_RS01365	COG5007	Belongs to the BolA IbaG family
AYN27_RS01375	COG3423	Transcriptional regulator
AYN27_RS01380	COG0142	geranyltranstransferase activity
AYN27_RS01395	COG0697	spore germination
AYN27_RS01405	COG2027	D-alanyl-D-alanine carboxypeptidase
AYN27_RS01410	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AYN27_RS01415	COG1534	Rna-binding protein
AYN27_RS01425	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AYN27_RS01430	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AYN27_RS01440	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AYN27_RS01480	COG0195	Participates in both transcription termination and antitermination
AYN27_RS01520	COG0513	Belongs to the DEAD box helicase family
AYN27_RS01525	COG0814	amino acid
AYN27_RS01530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AYN27_RS01535	COG0826	peptidase U32
AYN27_RS01540	COG0826	peptidase U32
AYN27_RS01545	COG3154	lipid carrier protein
AYN27_RS01550	COG3153	acetyltransferase
AYN27_RS01565	COG0693	protein deglycase activity
AYN27_RS01570	COG0702	epimerase
AYN27_RS01575	COG0701	Predicted permease
AYN27_RS01580	COG2823	Periplasmic or secreted lipoprotein
AYN27_RS01600	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AYN27_RS01605	COG3539	Fimbrial protein
AYN27_RS01610	COG3188	usher protein
AYN27_RS01615	COG3121	Chaperone
AYN27_RS01620	COG3539	Fimbrial protein
AYN27_RS01625	COG0363	glucosamine-6-phosphate deaminase activity
AYN27_RS01630	COG3716	PTS system mannose fructose sorbose family IID component
AYN27_RS01635	COG3715	PTS system
AYN27_RS01640	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AYN27_RS01650	COG2222	sugar isomerase
AYN27_RS01655	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AYN27_RS01660	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN27_RS01665	COG3716	PTS system mannose fructose sorbose family IID component
AYN27_RS01675	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AYN27_RS01690	COG1349	DNA-binding transcription factor activity
AYN27_RS01700	COG2002	toxin-antitoxin pair type II binding
AYN27_RS01705	COG2721	sulfolactate sulfo-lyase activity
AYN27_RS01710	COG2271	Major facilitator Superfamily
AYN27_RS01720	COG2084	Dehydrogenase
AYN27_RS01725	COG1929	Belongs to the glycerate kinase type-1 family
AYN27_RS01750	COG0583	DNA-binding transcription factor activity
AYN27_RS01760	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AYN27_RS01770	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AYN27_RS01775	COG1882	Formate acetyltransferase
AYN27_RS01780	COG0251	oxidation-reduction process
AYN27_RS01785	COG1760	l-serine dehydratase
AYN27_RS01795	COG0814	amino acid
AYN27_RS01810	COG1741	Belongs to the pirin family
AYN27_RS01815	COG0583	DNA-binding transcription factor activity
AYN27_RS01825	COG3152	Membrane
AYN27_RS01830	COG3152	Membrane
AYN27_RS01835	COG0435	Glutathione S-transferase
AYN27_RS01840	COG2259	Doxx family
AYN27_RS01850	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
AYN27_RS01855	COG4575	ribosome binding
AYN27_RS01860	COG1422	Protein of unknown function (DUF1090)
AYN27_RS01870	COG0586	Pfam SNARE associated Golgi protein
AYN27_RS01875	COG2186	Transcriptional regulator
AYN27_RS01905	COG2271	Major facilitator Superfamily
AYN27_RS01915	COG2721	sulfolactate sulfo-lyase activity
AYN27_RS01925	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AYN27_RS01930	COG0861	Integral membrane protein TerC family
AYN27_RS01935	COG0673	inositol 2-dehydrogenase activity
AYN27_RS01940	COG2949	membrane
AYN27_RS01945	COG1451	nucleotide metabolic process
AYN27_RS01955	COG4680	protein conserved in bacteria
AYN27_RS01960	COG5499	transcription regulator containing HTH domain
AYN27_RS01965	COG0446	pyridine nucleotide-disulphide oxidoreductase
AYN27_RS01965	COG1902	pentaerythritol trinitrate reductase activity
AYN27_RS01970	COG3408	Glycogen debranching enzyme
AYN27_RS01970	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
AYN27_RS01980	COG0531	amino acid
AYN27_RS01985	COG2731	YhcH YjgK YiaL family protein
AYN27_RS01990	COG3250	beta-galactosidase activity
AYN27_RS01995	COG1609	Transcriptional regulator
AYN27_RS02005	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AYN27_RS02020	COG0840	transmembrane signaling receptor activity
AYN27_RS02025	COG1695	Transcriptional regulator
AYN27_RS02035	COG2375	cellular response to nickel ion
AYN27_RS02090	COG0740	serine-type endopeptidase activity
AYN27_RS02115	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AYN27_RS02125	COG0358	DNA primase activity
AYN27_RS02130	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AYN27_RS02145	COG0471	metal ion transport
AYN27_RS02150	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AYN27_RS02155	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AYN27_RS02165	COG0583	DNA-binding transcription factor activity
AYN27_RS02175	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AYN27_RS02190	COG4991	sh3 domain protein
AYN27_RS02200	COG3025	triphosphatase activity
AYN27_RS02230	COG2268	Band 7 protein
AYN27_RS02235	COG1585	Membrane protein implicated in regulation of membrane protease activity
AYN27_RS02245	COG3539	Fimbrial protein
AYN27_RS02255	COG3188	usher protein
AYN27_RS02260	COG3539	Fimbrial protein
AYN27_RS02265	COG2960	long-chain fatty acid transporting porin activity
AYN27_RS02285	COG3384	dioxygenase
AYN27_RS02290	COG0754	glutathionylspermidine amidase activity
AYN27_RS02305	COG1538	Outer membrane efflux protein
AYN27_RS02310	COG0494	nUDIX hydrolase
AYN27_RS02315	COG3151	Protein conserved in bacteria
AYN27_RS02320	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AYN27_RS02325	COG3150	esterase
AYN27_RS02330	COG0187	DNA topoisomerase II activity
AYN27_RS02335	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AYN27_RS02340	COG2249	NAD(P)H dehydrogenase (quinone) activity
AYN27_RS02350	COG0642	Histidine kinase
AYN27_RS02355	COG0745	RESPONSE REGULATOR receiver
AYN27_RS02360	COG3111	PFAM Bacterial OB fold (BOF) protein
AYN27_RS02365	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AYN27_RS02375	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AYN27_RS02380	COG0204	Acyl-transferase
AYN27_RS02385	COG2132	Multicopper oxidase
AYN27_RS02390	COG1032	radical SAM domain protein
AYN27_RS02395	COG4238	major outer membrane lipoprotein
AYN27_RS02405	COG0656	L-ascorbic acid biosynthetic process
AYN27_RS02410	COG1979	alcohol dehydrogenase
AYN27_RS02415	COG2207	Transcriptional regulator
AYN27_RS02420	COG0586	Pfam SNARE associated Golgi protein
AYN27_RS02425	COG0626	cystathionine gamma-synthase activity
AYN27_RS02435	COG0811	peptide transport
AYN27_RS02440	COG0848	biopolymer transport protein
AYN27_RS02445	COG1028	Short-chain dehydrogenase reductase Sdr
AYN27_RS02455	COG0667	Aldo Keto reductase
AYN27_RS02475	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AYN27_RS02480	COG0437	4 iron, 4 sulfur cluster binding
AYN27_RS02485	COG5557	Pfam Polysulphide reductase, NrfD
AYN27_RS02490	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AYN27_RS02495	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AYN27_RS02500	COG1773	rubredoxin
AYN27_RS02510	COG0298	carbon dioxide binding
AYN27_RS02515	COG0625	glutathione transferase activity
AYN27_RS02520	COG0754	glutathionylspermidine amidase activity
AYN27_RS02530	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AYN27_RS02535	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AYN27_RS02540	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AYN27_RS02545	COG2244	polysaccharide biosynthetic process
AYN27_RS02555	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AYN27_RS02560	COG0795	lipopolysaccharide-transporting ATPase activity
AYN27_RS02570	COG0156	8-amino-7-oxononanoate synthase activity
AYN27_RS02575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AYN27_RS02585	COG0318	PFAM AMP-dependent synthetase and ligase
AYN27_RS02595	COG0456	acetyltransferase
AYN27_RS02600	COG2186	Transcriptional regulator
AYN27_RS02605	COG0277	FAD linked oxidase domain protein
AYN27_RS02610	COG0277	FAD linked oxidase domain protein
AYN27_RS02615	COG0247	lactate metabolic process
AYN27_RS02620	COG3193	protein, possibly involved in utilization of glycolate and propanediol
AYN27_RS02625	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AYN27_RS02630	COG1620	l-lactate permease
AYN27_RS02640	COG3064	Membrane
AYN27_RS02665	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AYN27_RS02670	COG1459	type II secretion system
AYN27_RS02675	COG2165	general secretion pathway protein
AYN27_RS02705	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AYN27_RS03040	COG1811	Na channel or pump
AYN27_RS03050	COG1982	Orn Lys Arg decarboxylase major
AYN27_RS03055	COG2211	Major facilitator Superfamily
AYN27_RS03070	COG1194	a g-specific adenine glycosylase
AYN27_RS03085	COG3171	Protein conserved in bacteria
AYN27_RS03095	COG0252	asparaginase activity
AYN27_RS03110	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AYN27_RS03115	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AYN27_RS03120	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AYN27_RS03135	COG0762	integral membrane protein
AYN27_RS03140	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AYN27_RS03145	COG2805	Type II/IV secretion system protein
AYN27_RS03160	COG0189	ligase activity
AYN27_RS03165	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AYN27_RS03170	COG2356	endonuclease I
AYN27_RS03180	COG2814	Major facilitator Superfamily
AYN27_RS03205	COG1166	arginine decarboxylase activity
AYN27_RS03230	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AYN27_RS03230	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN27_RS03235	COG3715	PTS system
AYN27_RS03240	COG3716	PTS system mannose fructose sorbose family IID component
AYN27_RS03255	COG0501	Belongs to the peptidase M48B family
AYN27_RS03260	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AYN27_RS03265	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN27_RS03270	COG2213	PTS system mannitol-specific
AYN27_RS03275	COG1063	alcohol dehydrogenase
AYN27_RS03280	COG1494	fructose-1,6-bisphosphatase
AYN27_RS03290	COG1072	(Pantothenic acid kinase))
AYN27_RS03295	COG1122	ATPase activity
AYN27_RS03300	COG1122	ATPase activity
AYN27_RS03335	COG0191	fructose-bisphosphate aldolase activity
AYN27_RS03345	COG0668	transmembrane transport
AYN27_RS03355	COG2968	Membrane
AYN27_RS03360	COG0583	DNA-binding transcription factor activity
AYN27_RS03365	COG0427	acetyl-CoA hydrolase
AYN27_RS03370	COG1024	Enoyl-CoA hydratase
AYN27_RS03375	COG1703	isobutyryl-CoA mutase activity
AYN27_RS03380	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AYN27_RS03380	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AYN27_RS03400	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AYN27_RS03420	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AYN27_RS03445	COG0006	proline dipeptidase activity
AYN27_RS03450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AYN27_RS03455	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AYN27_RS03475	COG1028	Short-chain dehydrogenase reductase Sdr
AYN27_RS03480	COG2723	6-phospho-beta-galactosidase activity
AYN27_RS03490	COG1272	protein, Hemolysin III
AYN27_RS03500	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AYN27_RS03510	COG0716	FMN binding
AYN27_RS03515	COG4974	Belongs to the 'phage' integrase family
AYN27_RS03520	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AYN27_RS03525	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AYN27_RS03550	COG2233	PERMEase
AYN27_RS03560	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AYN27_RS03560	COG0493	'glutamate synthase
AYN27_RS03565	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AYN27_RS03570	COG2252	PERMEase
AYN27_RS03575	COG0402	S-adenosylhomocysteine deaminase activity
AYN27_RS03580	COG2233	PERMEase
AYN27_RS03585	COG2080	2 iron, 2 sulfur cluster binding
AYN27_RS03585	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AYN27_RS03590	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AYN27_RS03595	COG0402	S-adenosylhomocysteine deaminase activity
AYN27_RS03600	COG0493	'glutamate synthase
AYN27_RS03600	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AYN27_RS03605	COG2068	MobA-Related Protein
AYN27_RS03610	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AYN27_RS03615	COG3608	succinylglutamate desuccinylase aspartoacylase
AYN27_RS03615	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AYN27_RS03620	COG0549	Belongs to the carbamate kinase family
AYN27_RS03630	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AYN27_RS03635	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AYN27_RS03640	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AYN27_RS03645	COG3829	transcription factor binding
AYN27_RS03650	COG2080	2 iron, 2 sulfur cluster binding
AYN27_RS03655	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AYN27_RS03660	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AYN27_RS03670	COG4942	peptidase
AYN27_RS03770	COG2197	response regulator
AYN27_RS03775	COG2197	response regulator
AYN27_RS03790	COG0457	Tetratricopeptide repeat
AYN27_RS03790	COG3710	Transcriptional regulator
AYN27_RS03820	COG3710	Transcriptional regulator
AYN27_RS03825	COG2771	luxR family
AYN27_RS03830	COG0814	amino acid
AYN27_RS03835	COG0183	Belongs to the thiolase family
AYN27_RS03845	COG1028	Short-chain dehydrogenase reductase Sdr
AYN27_RS03850	COG2814	Major facilitator Superfamily
AYN27_RS03855	COG1794	racemase activity, acting on amino acids and derivatives
AYN27_RS03860	COG0583	DNA-binding transcription factor activity
AYN27_RS03870	COG1609	Transcriptional regulator
AYN27_RS03885	COG0667	Aldo Keto reductase
AYN27_RS03895	COG0861	Integral membrane protein TerC family
AYN27_RS03910	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
AYN27_RS03930	COG2165	general secretion pathway protein
AYN27_RS03935	COG4795	General secretion pathway protein
AYN27_RS03945	COG4967	type IV pilus modification protein PilV
AYN27_RS03950	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AYN27_RS03955	COG1025	Belongs to the peptidase M16 family
AYN27_RS03960	COG1074	ATP-dependent DNA helicase activity
AYN27_RS03965	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AYN27_RS03970	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AYN27_RS03970	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AYN27_RS03980	COG0860	N-Acetylmuramoyl-L-alanine amidase
AYN27_RS03985	COG3711	transcriptional antiterminator
AYN27_RS03995	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AYN27_RS04030	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AYN27_RS04035	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AYN27_RS04040	COG2166	iron-sulfur cluster assembly
AYN27_RS04045	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AYN27_RS04055	COG0583	DNA-binding transcription factor activity
AYN27_RS04060	COG2363	Small membrane protein
AYN27_RS04070	COG1349	DNA-binding transcription factor activity
AYN27_RS04080	COG1070	Carbohydrate kinase
AYN27_RS04090	COG0738	Major facilitator superfamily
AYN27_RS04095	COG0235	Class ii aldolase
AYN27_RS04100	COG1454	alcohol dehydrogenase
AYN27_RS04110	COG1760	l-serine dehydratase
AYN27_RS04115	COG0814	amino acid
AYN27_RS04120	COG1611	Belongs to the LOG family
AYN27_RS04135	COG3098	single-species biofilm formation
AYN27_RS04140	COG0564	pseudouridine synthase activity
AYN27_RS04145	COG0716	FMN binding
AYN27_RS04150	COG2271	Major facilitator Superfamily
AYN27_RS04155	COG4948	Mandelate Racemase Muconate Lactonizing
AYN27_RS04160	COG4948	Mandelate Racemase Muconate Lactonizing
AYN27_RS04165	COG4999	Histidine kinase
AYN27_RS04165	COG3850	Histidine kinase
AYN27_RS04165	COG3437	response regulator, receiver
AYN27_RS04165	COG2205	protein histidine kinase activity
AYN27_RS04175	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AYN27_RS04180	COG2336	PFAM SpoVT AbrB
AYN27_RS04185	COG2337	Toxic component of a toxin-antitoxin (TA) module
AYN27_RS04190	COG3956	TIGRFAM MazG family protein
AYN27_RS04205	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AYN27_RS04215	COG0602	queuosine metabolic process
AYN27_RS04220	COG1070	Carbohydrate kinase
AYN27_RS04225	COG2223	nitrite transmembrane transporter activity
AYN27_RS04230	COG1028	Short-chain dehydrogenase reductase Sdr
AYN27_RS04235	COG0277	FAD linked oxidase domain protein
AYN27_RS04240	COG0477	Major facilitator Superfamily
AYN27_RS04245	COG2086	electron transfer activity
AYN27_RS04250	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AYN27_RS04255	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AYN27_RS04260	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AYN27_RS04265	COG0644	oxidoreductase
AYN27_RS04270	COG0720	synthase
AYN27_RS04300	COG1203	CRISPR-associated helicase, Cas3
AYN27_RS04315	COG1857	crispr-associated protein
AYN27_RS04330	COG1518	maintenance of DNA repeat elements
AYN27_RS04335	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AYN27_RS04340	COG2234	aminopeptidase activity
AYN27_RS04395	COG4942	peptidase
AYN27_RS04395	COG1388	LysM domain
AYN27_RS04400	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AYN27_RS04415	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AYN27_RS04425	COG2610	gluconate transmembrane transporter activity
AYN27_RS04430	COG3622	Belongs to the hyi family
AYN27_RS04435	COG0235	Class ii aldolase
AYN27_RS04440	COG3395	kinase activity
AYN27_RS04445	COG2084	Dehydrogenase
AYN27_RS04450	COG1349	DNA-binding transcription factor activity
AYN27_RS04455	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AYN27_RS04470	COG3604	Transcriptional regulator
AYN27_RS04475	COG0309	Hydrogenase expression formation protein (HypE)
AYN27_RS04480	COG0409	Hydrogenase expression formation protein
AYN27_RS04485	COG0298	carbon dioxide binding
AYN27_RS04490	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AYN27_RS04495	COG0375	protein maturation
AYN27_RS04505	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AYN27_RS04510	COG0651	ATP synthesis coupled electron transport
AYN27_RS04515	COG0650	Formate hydrogenlyase subunit 4
AYN27_RS04520	COG3261	NADH dehydrogenase
AYN27_RS04520	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AYN27_RS04525	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AYN27_RS04530	COG3260	NADH ubiquinone oxidoreductase 20
AYN27_RS04540	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AYN27_RS04550	COG4680	protein conserved in bacteria
AYN27_RS04555	COG5499	transcription regulator containing HTH domain
AYN27_RS04560	COG2723	6-phospho-beta-galactosidase activity
AYN27_RS04565	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AYN27_RS04565	COG1263	PTS System
AYN27_RS04570	COG1609	Transcriptional regulator
AYN27_RS04575	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AYN27_RS04580	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AYN27_RS04605	COG1349	DNA-binding transcription factor activity
AYN27_RS04610	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN27_RS04615	COG1028	Short-chain dehydrogenase reductase Sdr
AYN27_RS04625	COG3732	PTS system glucitol sorbitol-specific
AYN27_RS04630	COG3730	PTS system glucitol sorbitol-specific
AYN27_RS04635	COG2951	lytic endotransglycosylase activity
AYN27_RS04640	COG1546	Belongs to the CinA family
AYN27_RS04660	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AYN27_RS04690	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AYN27_RS04695	COG1238	metal cluster binding
AYN27_RS04710	COG2814	Major facilitator Superfamily
AYN27_RS04715	COG1566	PFAM secretion protein HlyD family protein
AYN27_RS04720	COG1846	Transcriptional regulator
AYN27_RS04730	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AYN27_RS04735	COG2814	Major facilitator Superfamily
AYN27_RS04740	COG2113	Glycine betaine
AYN27_RS04745	COG4176	ABC-type proline glycine betaine transport system permease component
AYN27_RS04750	COG4175	Glycine betaine
AYN27_RS04755	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AYN27_RS04760	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AYN27_RS04770	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AYN27_RS04775	COG4575	ribosome binding
AYN27_RS04790	COG2916	Histone family protein nucleoid-structuring protein H-NS
AYN27_RS04795	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AYN27_RS04800	COG0640	Transcriptional regulator
AYN27_RS04805	COG0401	homolog of Blt101
AYN27_RS04810	COG1652	LysM domain
AYN27_RS04815	COG1802	Transcriptional regulator
AYN27_RS04820	COG1113	amino acid transport
AYN27_RS04825	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AYN27_RS04830	COG1012	belongs to the aldehyde dehydrogenase family
AYN27_RS04835	COG0579	oxidoreductase
AYN27_RS04900	COG4712	double-strand break repair protein
AYN27_RS04940	COG0305	Participates in initiation and elongation during chromosome replication
AYN27_RS05235	COG0740	serine-type endopeptidase activity
AYN27_RS05320	COG5301	cellulose 1,4-beta-cellobiosidase activity
AYN27_RS05350	COG2867	negative regulation of translational initiation
AYN27_RS05360	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AYN27_RS05365	COG0497	DNA recombination
AYN27_RS05385	COG4536	flavin adenine dinucleotide binding
AYN27_RS05390	COG4137	Cytochrome C assembly protein
AYN27_RS05395	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AYN27_RS05420	COG2885	chlorophyll binding
AYN27_RS05425	COG2199	diguanylate cyclase activity
AYN27_RS05440	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AYN27_RS05445	COG0287	Prephenate dehydrogenase
AYN27_RS05445	COG1605	Chorismate mutase
AYN27_RS05450	COG1605	Chorismate mutase
AYN27_RS05450	COG0077	Prephenate dehydratase
AYN27_RS05465	COG1396	sequence-specific DNA binding
AYN27_RS05545	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AYN27_RS05580	COG4695	Portal protein
AYN27_RS05665	COG5301	cellulose 1,4-beta-cellobiosidase activity
AYN27_RS05665	COG5301	cellulose 1,4-beta-cellobiosidase activity
AYN27_RS05690	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AYN27_RS05750	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AYN27_RS05760	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AYN27_RS05765	COG0564	pseudouridine synthase activity
AYN27_RS05770	COG1496	oxidoreductase activity
AYN27_RS05775	COG0542	response to heat
AYN27_RS05805	COG0477	Major facilitator Superfamily
AYN27_RS05810	COG5544	Lipoprotein
AYN27_RS05815	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AYN27_RS05820	COG0045	succinate-CoA ligase (ADP-forming) activity
AYN27_RS05820	COG1042	CoA-binding domain protein
AYN27_RS05820	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AYN27_RS05825	COG3148	PFAM DTW domain containing protein
AYN27_RS05830	COG3118	belongs to the thioredoxin family
AYN27_RS05840	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AYN27_RS05860	COG0583	DNA-binding transcription factor activity
AYN27_RS05865	COG0513	Belongs to the DEAD box helicase family
AYN27_RS05875	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AYN27_RS05880	COG1595	DNA-templated transcription, initiation
AYN27_RS05885	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
AYN27_RS05890	COG3026	antisigma factor binding
AYN27_RS05895	COG3086	response to oxidative stress
AYN27_RS05905	COG0681	Belongs to the peptidase S26 family
AYN27_RS05930	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AYN27_RS05955	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AYN27_RS05960	COG1737	Transcriptional regulator
AYN27_RS05965	COG0560	Phosphoserine phosphatase
AYN27_RS05985	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AYN27_RS05985	COG0047	phosphoribosylformylglycinamidine synthase activity
AYN27_RS05990	COG2205	protein histidine kinase activity
AYN27_RS05995	COG3170	Tfp pilus assembly protein FimV
AYN27_RS06000	COG2204	response regulator
AYN27_RS06005	COG0347	Belongs to the P(II) protein family
AYN27_RS06010	COG1017	nitric oxide dioxygenase activity
AYN27_RS06010	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AYN27_RS06020	COG1940	carbohydrate kinase activity
AYN27_RS06035	COG1129	ABC transporter
AYN27_RS06040	COG1172	Belongs to the binding-protein-dependent transport system permease family
AYN27_RS06045	COG1063	alcohol dehydrogenase
AYN27_RS06050	COG2017	converts alpha-aldose to the beta-anomer
AYN27_RS06055	COG2259	Doxx family
AYN27_RS06080	COG4638	Rieske (2fe-2S)
AYN27_RS06085	COG0583	DNA-binding transcription factor activity
AYN27_RS06090	COG2814	Major facilitator Superfamily
AYN27_RS06095	COG3711	transcriptional antiterminator
AYN27_RS06100	COG1073	alpha beta
AYN27_RS06105	COG0483	inositol monophosphate 1-phosphatase activity
AYN27_RS06125	COG0822	iron-sulfur transferase activity
AYN27_RS06145	COG0633	Ferredoxin
AYN27_RS06150	COG2975	iron-sulfur cluster assembly
AYN27_RS06165	COG2897	thiosulfate sulfurtransferase activity
AYN27_RS06170	COG2373	Large extracellular alpha-helical protein
AYN27_RS06175	COG4953	penicillin-binding protein 1C
AYN27_RS06210	COG2976	Protein conserved in bacteria
AYN27_RS06225	COG1645	bacterial-type flagellum-dependent swarming motility
AYN27_RS06235	COG0516	GMP reductase activity
AYN27_RS06235	COG0517	IMP dehydrogenase activity
AYN27_RS06250	COG3133	Outer membrane lipoprotein
AYN27_RS06270	COG2200	EAL domain
AYN27_RS06275	COG0248	Ppx GppA phosphatase
AYN27_RS06280	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AYN27_RS06285	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AYN27_RS06305	COG2233	PERMEase
AYN27_RS06315	COG1393	Belongs to the ArsC family
AYN27_RS06320	COG4783	chaperone-mediated protein folding
AYN27_RS06325	COG0628	permease
AYN27_RS06335	COG2116	formate transmembrane transporter activity
AYN27_RS06340	COG3604	Transcriptional regulator
AYN27_RS06355	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AYN27_RS06360	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AYN27_RS06360	COG3261	NADH dehydrogenase
AYN27_RS06365	COG0651	ATP synthesis coupled electron transport
AYN27_RS06370	COG4237	Hydrogenase 4 membrane
AYN27_RS06375	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AYN27_RS06380	COG0650	Formate hydrogenlyase subunit 4
AYN27_RS06385	COG0651	ATP synthesis coupled electron transport
AYN27_RS06390	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AYN27_RS06395	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AYN27_RS06400	COG2716	regulation of RNA biosynthetic process
AYN27_RS06410	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AYN27_RS06430	COG2321	neutral zinc metallopeptidase
AYN27_RS06440	COG0400	carboxylic ester hydrolase activity
AYN27_RS06455	COG1393	Belongs to the ArsC family
AYN27_RS06470	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AYN27_RS06475	COG3850	Histidine kinase
AYN27_RS06480	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AYN27_RS06480	COG0493	'glutamate synthase
AYN27_RS06490	COG5342	invasion associated locus B
AYN27_RS06495	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AYN27_RS06500	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AYN27_RS06505	COG0281	malic enzyme
AYN27_RS06505	COG0280	phosphate acetyltransferase
AYN27_RS06515	COG4810	utilization protein
AYN27_RS06520	COG4917	ethanolamine utilization protein
AYN27_RS06525	COG4766	ethanolamine catabolic process
AYN27_RS06530	COG4812	Cobalamin adenosyltransferase
AYN27_RS06535	COG0280	phosphate acetyltransferase
AYN27_RS06540	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AYN27_RS06545	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
AYN27_RS06550	COG1012	belongs to the aldehyde dehydrogenase family
AYN27_RS06555	COG4820	ethanolamine utilization protein (EutJ)
AYN27_RS06560	COG1454	alcohol dehydrogenase
AYN27_RS06565	COG3192	ethanolamine utilization protein
AYN27_RS06570	COG4819	ethanolamine utilization protein
AYN27_RS06575	COG4303	Ethanolamine ammonia lyase large subunit
AYN27_RS06585	COG4816	utilization protein
AYN27_RS06590	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AYN27_RS06595	COG2207	Transcriptional regulator
AYN27_RS06605	COG0860	N-Acetylmuramoyl-L-alanine amidase
AYN27_RS06625	COG2837	iron assimilation
AYN27_RS06630	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AYN27_RS06635	COG1263	PTS System
AYN27_RS06635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AYN27_RS06650	COG1028	Short-chain dehydrogenase reductase Sdr
AYN27_RS06655	COG4150	thiosulfate binding
AYN27_RS06660	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AYN27_RS06665	COG4208	sulfate ABC transporter
AYN27_RS06670	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AYN27_RS06675	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AYN27_RS06690	COG2190	(PTS) system
AYN27_RS06695	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AYN27_RS06700	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN27_RS06705	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AYN27_RS06725	COG3530	Putative quorum-sensing-regulated virulence factor
AYN27_RS06730	COG0385	Bile acid
AYN27_RS06735	COG0583	DNA-binding transcription factor activity
AYN27_RS06745	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AYN27_RS06750	COG2211	Major facilitator Superfamily
AYN27_RS06760	COG0583	DNA-binding transcription factor activity
AYN27_RS06790	COG3415	Transposase
AYN27_RS06795	COG3415	Transposase
AYN27_RS06815	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AYN27_RS06840	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AYN27_RS06845	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AYN27_RS06850	COG0006	proline dipeptidase activity
AYN27_RS06855	COG1363	Peptidase, m42
AYN27_RS06865	COG2207	Transcriptional regulator
AYN27_RS06875	COG3275	phosphorelay sensor kinase activity
AYN27_RS06880	COG0436	Aminotransferase
AYN27_RS06890	COG1560	Kdo2-lipid A biosynthetic process
AYN27_RS06920	COG0028	Belongs to the TPP enzyme family
AYN27_RS06925	COG0679	Auxin Efflux Carrier
AYN27_RS06930	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AYN27_RS06935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AYN27_RS06935	COG2198	Histidine kinase
AYN27_RS06935	COG2205	protein histidine kinase activity
AYN27_RS06935	COG0784	Response regulator, receiver
AYN27_RS06940	COG2197	response regulator
AYN27_RS06945	COG1566	PFAM secretion protein HlyD family protein
AYN27_RS06950	COG0477	Major facilitator Superfamily
AYN27_RS07065	COG5532	Uncharacterized conserved protein (DUF2303)
AYN27_RS07105	COG3561	AntA/AntB antirepressor
AYN27_RS07110	COG3646	Phage regulatory protein
AYN27_RS07175	COG2842	Transposition protein
AYN27_RS07205	COG4396	Host-nuclease inhibitor protein Gam
AYN27_RS07260	COG5566	PFAM Mor transcription activator
AYN27_RS07295	COG4373	Mu-like prophage FluMu protein gp28
AYN27_RS07300	COG4383	Mu-like prophage protein gp29
AYN27_RS07305	COG2369	cell adhesion
AYN27_RS07310	COG5005	Phage virion morphogenesis
AYN27_RS07315	COG4388	Caudovirus prohead serine protease
AYN27_RS07320	COG4397	Mu-like prophage major head subunit gpT
AYN27_RS07345	COG4386	tail sheath protein
AYN27_RS07355	COG4518	Phage tail assembly chaperone proteins, E, or 41 or 14
AYN27_RS07375	COG4384	Bacteriophage Mu Gp45 protein
AYN27_RS07385	COG3299	homolog of phage Mu protein gp47
AYN27_RS07415	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AYN27_RS07530	COG3772	lysozyme
AYN27_RS07675	COG2116	formate transmembrane transporter activity
AYN27_RS07685	COG2853	Lipoprotein
AYN27_RS07700	COG2067	long-chain fatty acid transport protein
AYN27_RS07715	COG3691	Protein conserved in bacteria
AYN27_RS07730	COG2062	phosphohistidine phosphatase, SixA
AYN27_RS07735	COG3539	Fimbrial protein
AYN27_RS07740	COG3188	usher protein
AYN27_RS07745	COG3121	Chaperone
AYN27_RS07750	COG3539	Fimbrial protein
AYN27_RS07755	COG3539	Fimbrial protein
AYN27_RS07760	COG3539	Fimbrial protein
AYN27_RS07790	COG0730	response to heat
AYN27_RS07795	COG3101	peptidyl-lysine hydroxylation
AYN27_RS07810	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AYN27_RS07820	COG2814	Major facilitator Superfamily
AYN27_RS07835	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AYN27_RS07845	COG0586	Pfam SNARE associated Golgi protein
AYN27_RS07855	COG0285	dihydrofolate synthase activity
AYN27_RS07860	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AYN27_RS07865	COG1286	toxin biosynthetic process
AYN27_RS07870	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AYN27_RS07875	COG0163	prenyltransferase activity
AYN27_RS07880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AYN27_RS07885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AYN27_RS07890	COG4215	(ABC) transporter
AYN27_RS07895	COG4160	amino acid transport
AYN27_RS07900	COG4598	ABC transporter
AYN27_RS07905	COG5464	transposase or invertase
AYN27_RS07910	COG1090	epimerase
AYN27_RS07915	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AYN27_RS07920	COG0625	glutathione transferase activity
AYN27_RS07925	COG0625	glutathione transferase activity
AYN27_RS07930	COG0622	Phosphoesterase
AYN27_RS07935	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AYN27_RS07940	COG1288	antiporter activity
AYN27_RS07945	COG0857	belongs to the CobB CobQ family
AYN27_RS07945	COG0280	phosphate acetyltransferase
AYN27_RS07950	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AYN27_RS07965	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AYN27_RS07970	COG0471	metal ion transport
AYN27_RS07970	COG0490	domain, Protein
AYN27_RS07980	COG0436	Aminotransferase
AYN27_RS07990	COG0583	DNA-binding transcription factor activity
AYN27_RS08010	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AYN27_RS08015	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AYN27_RS08020	COG1034	ATP synthesis coupled electron transport
AYN27_RS08035	COG0839	Belongs to the complex I subunit 6 family
AYN27_RS08045	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AYN27_RS08050	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AYN27_RS08065	COG2234	aminopeptidase activity
AYN27_RS08070	COG2304	oxidoreductase activity
AYN27_RS08085	COG2153	protein acetylation
AYN27_RS08090	COG4575	ribosome binding
AYN27_RS08095	COG1169	isochorismate synthase
AYN27_RS08110	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AYN27_RS08120	COG0318	PFAM AMP-dependent synthetase and ligase
AYN27_RS08190	COG5464	transposase or invertase
AYN27_RS08195	COG0247	lactate metabolic process
AYN27_RS08205	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AYN27_RS08215	COG2271	Major facilitator Superfamily
AYN27_RS08220	COG0584	glycerophosphoryl diester phosphodiesterase
AYN27_RS08225	COG0583	DNA-binding transcription factor activity
AYN27_RS08230	COG3642	lipopolysaccharide core region biosynthetic process
AYN27_RS08235	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AYN27_RS08240	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AYN27_RS08245	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AYN27_RS08255	COG3468	outer membrane autotransporter barrel domain protein
AYN27_RS08265	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AYN27_RS08270	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
AYN27_RS08275	COG3234	Protein of unknown function (DUF1175)
AYN27_RS08280	COG0582	viral genome integration into host DNA
AYN27_RS08350	COG3772	lysozyme
AYN27_RS08395	COG2373	Large extracellular alpha-helical protein
AYN27_RS08400	COG5445	Predicted secreted protein (DUF2300)
AYN27_RS08405	COG4676	Protein conserved in bacteria
AYN27_RS08410	COG0784	Response regulator, receiver
AYN27_RS08410	COG2205	protein histidine kinase activity
AYN27_RS08415	COG2197	response regulator
AYN27_RS08420	COG2198	Histidine kinase
AYN27_RS08420	COG0642	Histidine kinase
AYN27_RS08435	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AYN27_RS08440	COG1477	protein flavinylation
AYN27_RS08445	COG2169	Transcriptional regulator
AYN27_RS08445	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AYN27_RS08450	COG3145	DNA-N1-methyladenine dioxygenase activity
AYN27_RS08455	COG4615	Cyclic peptide transporter
AYN27_RS08475	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AYN27_RS08475	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
AYN27_RS08480	COG3062	negative regulation of establishment of protein localization
AYN27_RS08490	COG0437	4 iron, 4 sulfur cluster binding
AYN27_RS08495	COG0348	domain, Protein
AYN27_RS08500	COG3043	anaerobic respiration
AYN27_RS08505	COG3005	denitrification pathway
AYN27_RS08510	COG4133	protoheme IX ABC transporter activity
AYN27_RS08515	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AYN27_RS08520	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AYN27_RS08525	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AYN27_RS08535	COG1138	Cytochrome C-type biogenesis protein
AYN27_RS08540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AYN27_RS08545	COG4235	cytochrome complex assembly
AYN27_RS08545	COG3088	subunit of a heme lyase
AYN27_RS08550	COG2197	response regulator
AYN27_RS08565	COG3468	outer membrane autotransporter barrel domain protein
AYN27_RS08640	COG0582	viral genome integration into host DNA
AYN27_RS08650	COG3083	sulfuric ester hydrolase activity
AYN27_RS08670	COG1061	Type III restriction enzyme res subunit
AYN27_RS08680	COG1187	pseudouridine synthase activity
AYN27_RS08685	COG2814	Major facilitator Superfamily
AYN27_RS08700	COG4172	Belongs to the ABC transporter superfamily
AYN27_RS08705	COG4239	(ABC) transporter, permease
AYN27_RS08710	COG4174	ABC transporter (Permease)
AYN27_RS08715	COG4166	transmembrane transport
AYN27_RS08720	COG2200	EAL domain
AYN27_RS08725	COG0791	NLP P60 protein
AYN27_RS08730	COG0671	phosphoesterase, PA-phosphatase related
AYN27_RS08735	COG0523	cobalamin synthesis protein
AYN27_RS08740	COG0246	Mannitol dehydrogenase
AYN27_RS08755	COG2814	Major facilitator Superfamily
AYN27_RS08760	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN27_RS08760	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN27_RS08765	COG1105	Belongs to the carbohydrate kinase PfkB family
AYN27_RS08770	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AYN27_RS08770	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AYN27_RS08770	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AYN27_RS08775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AYN27_RS08780	COG2313	pseudouridylate synthase activity
AYN27_RS08785	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AYN27_RS08790	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AYN27_RS08815	COG2855	membrane
AYN27_RS08820	COG0583	DNA-binding transcription factor activity
AYN27_RS08830	COG0833	amino acid
AYN27_RS08840	COG4771	TonB-dependent receptor
AYN27_RS08865	COG2311	Membrane
AYN27_RS08875	COG1609	Transcriptional regulator
AYN27_RS08880	COG1879	ABC-type sugar transport system periplasmic component
AYN27_RS08885	COG1129	ABC transporter
AYN27_RS08890	COG4211	Belongs to the binding-protein-dependent transport system permease family
AYN27_RS08895	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AYN27_RS08895	COG0167	dihydroorotate dehydrogenase activity
AYN27_RS08900	COG0493	'glutamate synthase
AYN27_RS08910	COG2949	membrane
AYN27_RS08920	COG1346	cytolysis
AYN27_RS08930	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AYN27_RS08955	COG1028	Short-chain dehydrogenase reductase Sdr
AYN27_RS08960	COG0586	Pfam SNARE associated Golgi protein
AYN27_RS08970	COG1686	Belongs to the peptidase S11 family
AYN27_RS08975	COG0277	FAD linked oxidase domain protein
AYN27_RS08980	COG1472	Belongs to the glycosyl hydrolase 3 family
AYN27_RS08985	COG1732	Glycine betaine
AYN27_RS08990	COG1174	glycine betaine transport
AYN27_RS08995	COG1125	glycine betaine transport
AYN27_RS09000	COG1174	glycine betaine transport
AYN27_RS09010	COG0789	Transcriptional regulator
AYN27_RS09015	COG3275	phosphorelay sensor kinase activity
AYN27_RS09020	COG3279	Response regulator of the LytR AlgR family
AYN27_RS09025	COG4807	Protein conserved in bacteria
AYN27_RS09030	COG4808	Protein conserved in bacteria
AYN27_RS09040	COG3552	Protein containing von Willebrand factor type A (VWA) domain
AYN27_RS09045	COG2425	protein containing a von Willebrand factor type A (vWA) domain
AYN27_RS09050	COG0714	Associated with various cellular activities
AYN27_RS09060	COG3831	ATPase activity
AYN27_RS09075	COG0489	protein tyrosine kinase activity
AYN27_RS09090	COG3539	Fimbrial protein
AYN27_RS09095	COG3121	Chaperone
AYN27_RS09100	COG3188	usher protein
AYN27_RS09105	COG3539	Fimbrial protein
AYN27_RS09110	COG5455	response to cobalt ion
AYN27_RS09115	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AYN27_RS09130	COG0351	phosphomethylpyrimidine kinase
AYN27_RS09135	COG3757	hydrolase, family 25
AYN27_RS09140	COG2188	Transcriptional regulator
AYN27_RS09145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AYN27_RS09150	COG1397	ADP-ribosylglycohydrolase
AYN27_RS09155	COG2211	Major facilitator Superfamily
AYN27_RS09160	COG1830	Aldolase
AYN27_RS09175	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN27_RS09180	COG3414	Phosphotransferase system galactitol-specific IIB component
AYN27_RS09185	COG3775	system Galactitol-specific IIC component
AYN27_RS09190	COG1063	alcohol dehydrogenase
AYN27_RS09215	COG0826	peptidase U32
AYN27_RS09225	COG3609	addiction module antidote protein, CC2985 family
AYN27_RS09235	COG0745	RESPONSE REGULATOR receiver
AYN27_RS09240	COG2205	protein histidine kinase activity
AYN27_RS09280	COG4245	von Willebrand factor, type A
AYN27_RS09285	COG0631	protein serine/threonine phosphatase activity
AYN27_RS09290	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
AYN27_RS09295	COG0443	Heat shock 70 kDa protein
AYN27_RS09300	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AYN27_RS09305	COG5002	protein histidine kinase activity
AYN27_RS09305	COG3447	MASE1 domain protein
AYN27_RS09305	COG5001	Diguanylate cyclase
AYN27_RS09310	COG0572	uridine kinase
AYN27_RS09320	COG2982	Protein involved in outer membrane biogenesis
AYN27_RS09335	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AYN27_RS09340	COG3206	protein involved in exopolysaccharide biosynthesis
AYN27_RS09340	COG0489	protein tyrosine kinase activity
AYN27_RS09345	COG0463	Glycosyl transferase, family 2
AYN27_RS09350	COG1045	serine acetyltransferase
AYN27_RS09365	COG1216	Glycosyl transferase, family 2
AYN27_RS09370	COG0110	maltose O-acetyltransferase activity
AYN27_RS09385	COG2963	transposase activity
AYN27_RS09410	COG0438	transferase activity, transferring glycosyl groups
AYN27_RS09415	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AYN27_RS09420	COG1051	belongs to the nudix hydrolase family
AYN27_RS09430	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AYN27_RS09465	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AYN27_RS09505	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AYN27_RS09540	COG2161	toxin-antitoxin pair type II binding
AYN27_RS09545	COG4115	mRNA cleavage
AYN27_RS09550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AYN27_RS09555	COG0583	DNA-binding transcription factor activity
AYN27_RS09565	COG0531	amino acid
AYN27_RS09570	COG2391	methyltransferase activity
AYN27_RS09575	COG0425	Belongs to the sulfur carrier protein TusA family
AYN27_RS09580	COG2925	Exonuclease
AYN27_RS09585	COG1686	Belongs to the peptidase S11 family
AYN27_RS09640	COG2003	Belongs to the UPF0758 family
AYN27_RS09710	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
AYN27_RS09725	COG1376	ErfK ybiS ycfS ynhG family protein
AYN27_RS09735	COG0583	DNA-binding transcription factor activity
AYN27_RS09740	COG0583	DNA-binding transcription factor activity
AYN27_RS09765	COG0217	transcriptional regulatory protein
AYN27_RS09770	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AYN27_RS09810	COG0582	viral genome integration into host DNA
AYN27_RS09830	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AYN27_RS09890	COG1484	DNA-dependent DNA replication
AYN27_RS09895	COG1846	Transcriptional regulator
AYN27_RS09930	COG3111	PFAM Bacterial OB fold (BOF) protein
AYN27_RS09940	COG1403	HNH endonuclease
AYN27_RS09945	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
AYN27_RS09960	COG2207	Transcriptional regulator
AYN27_RS09980	COG4372	Transposase
AYN27_RS09985	COG3436	PFAM IS66 Orf2 family protein
AYN27_RS10040	COG3772	lysozyme
AYN27_RS10070	COG4220	transposase activity
AYN27_RS10175	COG5301	cellulose 1,4-beta-cellobiosidase activity
AYN27_RS10195	COG3038	cytochrome b561
AYN27_RS10200	COG3443	Belongs to the bacterial solute-binding protein 9 family
AYN27_RS10215	COG2351	hydroxyisourate hydrolase activity
AYN27_RS10220	COG0745	RESPONSE REGULATOR receiver
AYN27_RS10225	COG2205	protein histidine kinase activity
AYN27_RS10240	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AYN27_RS10250	COG1418	mRNA catabolic process
AYN27_RS10255	COG0270	DNA (cytosine-5-)-methyltransferase activity
AYN27_RS10260	COG3727	T/G mismatch-specific endonuclease activity
AYN27_RS10265	COG0697	spore germination
AYN27_RS10270	COG2354	Protein conserved in bacteria
AYN27_RS10275	COG5475	Uncharacterized small protein (DUF2158)
AYN27_RS10285	COG3706	GGDEF domain
AYN27_RS10305	COG2197	response regulator
AYN27_RS10310	COG1684	flagellar biosynthetic protein fliR
AYN27_RS10315	COG1987	bacterial-type flagellum assembly
AYN27_RS10320	COG1338	Plays a role in the flagellum-specific transport system
AYN27_RS10325	COG3190	flagellar
AYN27_RS10330	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AYN27_RS10335	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AYN27_RS10340	COG1580	Controls the rotational direction of flagella during chemotaxis
AYN27_RS10345	COG3144	bacterial-type flagellum assembly
AYN27_RS10350	COG2882	bacterial-type flagellum organization
AYN27_RS10355	COG1157	protein secretion by the type III secretion system
AYN27_RS10360	COG1317	bacterial-type flagellum organization
AYN27_RS10365	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AYN27_RS10370	COG1766	The M ring may be actively involved in energy transduction
AYN27_RS10380	COG2076	Multidrug Resistance protein
AYN27_RS10385	COG1881	PFAM PEBP family protein
AYN27_RS10390	COG2207	Transcriptional regulator
AYN27_RS10400	COG0675	Transposase, IS605 OrfB family
AYN27_RS10405	COG2135	peptidase activity
AYN27_RS10410	COG0425	Belongs to the sulfur carrier protein TusA family
AYN27_RS10415	COG2391	methyltransferase activity
AYN27_RS10430	COG0366	Alpha amylase catalytic
AYN27_RS10440	COG1516	flagellar protein fliS
AYN27_RS10455	COG1191	sigma factor activity
AYN27_RS10465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AYN27_RS10475	COG0765	amino acid transport
AYN27_RS10480	COG1126	abc transporter atp-binding protein
AYN27_RS10485	COG2197	response regulator
AYN27_RS10495	COG2197	response regulator
AYN27_RS10525	COG3318	Belongs to the UPF0149 family
AYN27_RS10525	COG3012	SEC-C Motif Domain Protein
AYN27_RS10530	COG0814	amino acid
AYN27_RS10540	COG1528	Iron-storage protein
AYN27_RS10560	COG1528	Iron-storage protein
AYN27_RS10570	COG1879	ABC-type sugar transport system periplasmic component
AYN27_RS10575	COG1129	ABC transporter
AYN27_RS10580	COG1172	Belongs to the binding-protein-dependent transport system permease family
AYN27_RS10585	COG1877	trehalose-phosphatase activity
AYN27_RS10595	COG0589	response to stress
AYN27_RS10610	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AYN27_RS10615	COG1360	Flagellar Motor Protein
AYN27_RS10620	COG0643	Histidine kinase
AYN27_RS10620	COG2198	Histidine kinase
AYN27_RS10625	COG0835	chemotaxis
AYN27_RS10630	COG0840	transmembrane signaling receptor activity
AYN27_RS10635	COG0840	transmembrane signaling receptor activity
AYN27_RS10640	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AYN27_RS10645	COG2201	protein-glutamate methylesterase activity
AYN27_RS10650	COG0745	RESPONSE REGULATOR receiver
AYN27_RS10655	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AYN27_RS10660	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AYN27_RS10665	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AYN27_RS10675	COG3755	Protein conserved in bacteria
AYN27_RS10690	COG3102	Protein conserved in bacteria
AYN27_RS10700	COG3005	denitrification pathway
AYN27_RS10705	COG0243	molybdopterin cofactor binding
AYN27_RS10720	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AYN27_RS10725	COG1801	Protein of unknown function DUF72
AYN27_RS10730	COG1335	isochorismatase
AYN27_RS10740	COG0494	nUDIX hydrolase
AYN27_RS10745	COG0217	transcriptional regulatory protein
AYN27_RS10775	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AYN27_RS10785	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AYN27_RS10790	COG0739	heme binding
AYN27_RS10795	COG1560	Kdo2-lipid A biosynthetic process
AYN27_RS10815	COG3842	ATPase activity
AYN27_RS10825	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AYN27_RS10835	COG2182	Extracellular solute-binding protein
AYN27_RS10840	COG1175	transmembrane transport
AYN27_RS10845	COG3833	ABC-type maltose transport systems, permease component
AYN27_RS10870	COG0469	pyruvate kinase activity
AYN27_RS10875	COG1737	Transcriptional regulator
AYN27_RS10880	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AYN27_RS10885	COG0129	dihydroxy-acid dehydratase activity
AYN27_RS10890	COG0800	Aldolase
AYN27_RS10900	COG3141	response to X-ray
AYN27_RS10910	COG2979	Protein of unknown function (DUF533)
AYN27_RS10915	COG1770	oligopeptidase
AYN27_RS10920	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AYN27_RS10925	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AYN27_RS10935	COG2372	response to copper ion
AYN27_RS10940	COG1276	copper resistance
AYN27_RS10950	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AYN27_RS10970	COG3008	intermembrane lipid transfer
AYN27_RS10975	COG2995	paraquat-inducible protein a
AYN27_RS10980	COG1956	GAF domain-containing protein
AYN27_RS10990	COG0793	Belongs to the peptidase S41A family
AYN27_RS11000	COG2814	Major facilitator Superfamily
AYN27_RS11005	COG1414	Transcriptional regulator
AYN27_RS11040	COG2226	methyltransferase
AYN27_RS11060	COG3716	PTS system mannose fructose sorbose family IID component
AYN27_RS11065	COG3715	PTS system
AYN27_RS11070	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN27_RS11070	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AYN27_RS11085	COG1253	flavin adenine dinucleotide binding
AYN27_RS11090	COG2200	EAL domain
AYN27_RS11095	COG1760	l-serine dehydratase
AYN27_RS11105	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AYN27_RS11120	COG0251	oxidation-reduction process
AYN27_RS11125	COG1199	ATP-dependent helicase activity
AYN27_RS11130	COG1214	PFAM Peptidase M22, glycoprotease
AYN27_RS11135	COG3065	identical protein binding
AYN27_RS11140	COG0318	PFAM AMP-dependent synthetase and ligase
AYN27_RS11145	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AYN27_RS11150	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AYN27_RS11155	COG4638	Rieske (2fe-2S)
AYN27_RS11160	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AYN27_RS11165	COG0473	3-isopropylmalate dehydrogenase activity
AYN27_RS11170	COG0583	DNA-binding transcription factor activity
AYN27_RS11180	COG3615	Tellurite resistance protein tehB
AYN27_RS11195	COG0675	Transposase, IS605 OrfB family
AYN27_RS11205	COG2261	transglycosylase associated protein
AYN27_RS11220	COG2199	diguanylate cyclase activity
AYN27_RS11220	COG2203	Gaf domain
AYN27_RS11225	COG3042	response to heat
AYN27_RS11230	COG3189	MarR family transcriptional regulator
AYN27_RS11235	COG2807	transmembrane transport
AYN27_RS11240	COG2207	Transcriptional regulator
AYN27_RS11255	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AYN27_RS11260	COG2199	diguanylate cyclase activity
AYN27_RS11265	COG2199	diguanylate cyclase activity
AYN27_RS11275	COG2766	serine protein kinase
AYN27_RS11280	COG3713	MltA-interacting MipA family protein
AYN27_RS11285	COG0656	L-ascorbic acid biosynthetic process
AYN27_RS11290	COG0676	glucose-6-phosphate 1-epimerase activity
AYN27_RS11295	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AYN27_RS11305	COG3139	Protein of unknown function (DUF1315)
AYN27_RS11310	COG1335	isochorismatase
AYN27_RS11315	COG0252	asparaginase activity
AYN27_RS11320	COG0616	signal peptide processing
AYN27_RS11330	COG0778	Nitroreductase
AYN27_RS11345	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AYN27_RS11355	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AYN27_RS11365	COG0494	nUDIX hydrolase
AYN27_RS11370	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AYN27_RS11375	COG2897	thiosulfate sulfurtransferase activity
AYN27_RS11380	COG4136	ATPase activity
AYN27_RS11385	COG4135	transport system, permease component
AYN27_RS11390	COG4134	Bacterial extracellular solute-binding protein
AYN27_RS11395	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AYN27_RS11400	COG0398	Pfam SNARE associated Golgi protein
AYN27_RS11410	COG0398	Pfam SNARE associated Golgi protein
AYN27_RS11415	COG0708	Exodeoxyribonuclease III
AYN27_RS11450	COG3678	ATP-independent chaperone mediated protein folding
AYN27_RS11460	COG0322	excinuclease ABC activity
AYN27_RS11470	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AYN27_RS11480	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AYN27_RS11485	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AYN27_RS11490	COG1447	Phosphotransferase system cellobiose-specific component IIA
AYN27_RS11495	COG2169	Transcriptional regulator
AYN27_RS11495	COG1917	Cupin 2, conserved barrel domain protein
AYN27_RS11500	COG1486	melibiose metabolic process
AYN27_RS11510	COG0753	catalase activity
AYN27_RS11530	COG1823	symporter activity
AYN27_RS11535	COG1988	membrane-bound metal-dependent
AYN27_RS11540	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AYN27_RS11550	COG3001	Fructosamine kinase
AYN27_RS11560	COG1105	Belongs to the carbohydrate kinase PfkB family
AYN27_RS11565	COG3137	Salt-induced outer membrane protein
AYN27_RS11675	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AYN27_RS11680	COG5301	cellulose 1,4-beta-cellobiosidase activity
AYN27_RS11765	COG4695	Portal protein
AYN27_RS11830	COG0386	Belongs to the glutathione peroxidase family
AYN27_RS11840	COG0791	NLP P60 protein
AYN27_RS11845	COG2200	EAL domain
AYN27_RS11855	COG4256	Hemin uptake protein
AYN27_RS11860	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AYN27_RS11875	COG0574	Belongs to the PEP-utilizing enzyme family
AYN27_RS11875	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AYN27_RS11880	COG0318	PFAM AMP-dependent synthetase and ligase
AYN27_RS11885	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AYN27_RS11890	COG0644	oxidoreductase
AYN27_RS11895	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AYN27_RS11900	COG2086	electron transfer activity
AYN27_RS11910	COG1917	Cupin 2, conserved barrel domain protein
AYN27_RS11910	COG2207	Transcriptional regulator
AYN27_RS11915	COG1960	acyl-CoA dehydrogenase activity
AYN27_RS11935	COG2271	Major facilitator Superfamily
AYN27_RS11940	COG0738	Major facilitator superfamily
AYN27_RS11955	COG0628	permease
AYN27_RS11965	COG0247	lactate metabolic process
AYN27_RS11965	COG0277	FAD linked oxidase domain protein
AYN27_RS11970	COG2050	protein possibly involved in aromatic compounds catabolism
AYN27_RS11980	COG0316	Belongs to the HesB IscA family
AYN27_RS11985	COG0719	Fe-S assembly protein
AYN27_RS11990	COG0396	ATPase activity
AYN27_RS11995	COG0719	Fe-S assembly protein
AYN27_RS12010	COG1376	ErfK ybiS ycfS ynhG family protein
AYN27_RS12015	COG4238	major outer membrane lipoprotein
AYN27_RS12020	COG0469	pyruvate kinase activity
AYN27_RS12030	COG0437	4 iron, 4 sulfur cluster binding
AYN27_RS12035	COG2414	aldehyde ferredoxin oxidoreductase
AYN27_RS12045	COG0437	4 iron, 4 sulfur cluster binding
AYN27_RS12050	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
AYN27_RS12060	COG4529	Protein conserved in bacteria
AYN27_RS12080	COG3468	outer membrane autotransporter barrel domain protein
AYN27_RS12090	COG0307	riboflavin synthase, alpha
AYN27_RS12095	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AYN27_RS12100	COG2814	Major facilitator Superfamily
AYN27_RS12105	COG0583	DNA-binding transcription factor activity
AYN27_RS12125	COG2814	Major facilitator Superfamily
AYN27_RS12130	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AYN27_RS12135	COG0791	NLP P60 protein
AYN27_RS12140	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AYN27_RS12145	COG1201	RNA secondary structure unwinding
AYN27_RS12155	COG0346	lactoylglutathione lyase activity
AYN27_RS12160	COG1902	pentaerythritol trinitrate reductase activity
AYN27_RS12165	COG1309	transcriptional regulator
AYN27_RS12170	COG3313	Fe-S protein
AYN27_RS12175	COG4989	oxidoreductase activity
AYN27_RS12180	COG2032	superoxide dismutase activity
AYN27_RS12185	COG1289	transmembrane transporter activity
AYN27_RS12190	COG1566	PFAM secretion protein HlyD family protein
AYN27_RS12205	COG3133	Outer membrane lipoprotein
AYN27_RS12215	COG3895	Periplasmic Protein
AYN27_RS12230	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AYN27_RS12235	COG0625	glutathione transferase activity
AYN27_RS12240	COG3104	oligopeptide transport
AYN27_RS12250	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AYN27_RS12260	COG4659	FMN binding
AYN27_RS12305	COG0673	inositol 2-dehydrogenase activity
AYN27_RS12315	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AYN27_RS12320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AYN27_RS12320	COG1263	PTS System
AYN27_RS12325	COG1609	Transcriptional regulator
AYN27_RS12330	COG1028	Short-chain dehydrogenase reductase Sdr
AYN27_RS12335	COG1309	transcriptional regulator
AYN27_RS12340	COG3250	beta-galactosidase activity
AYN27_RS12355	COG5339	Protein conserved in bacteria
AYN27_RS12360	COG1482	cell wall glycoprotein biosynthetic process
AYN27_RS12365	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AYN27_RS12365	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AYN27_RS12370	COG0114	fumarate hydratase activity
AYN27_RS12380	COG2205	protein histidine kinase activity
AYN27_RS12385	COG0745	RESPONSE REGULATOR receiver
AYN27_RS12390	COG3136	membrane protein required for alginate biosynthesis
AYN27_RS12400	COG0531	amino acid
AYN27_RS12415	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AYN27_RS12420	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AYN27_RS12425	COG0628	permease
AYN27_RS12445	COG3591	Belongs to the peptidase S1B family
AYN27_RS12465	COG2814	Major facilitator Superfamily
AYN27_RS12470	COG0583	DNA-binding transcription factor activity
AYN27_RS12475	COG1940	carbohydrate kinase activity
AYN27_RS12480	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AYN27_RS12490	COG3381	protein complex oligomerization
AYN27_RS12495	COG3302	dmso reductase anchor subunit
AYN27_RS12500	COG0437	4 iron, 4 sulfur cluster binding
AYN27_RS12505	COG0243	molybdopterin cofactor binding
AYN27_RS12510	COG0243	molybdopterin cofactor binding
AYN27_RS12525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AYN27_RS12545	COG4948	Mandelate Racemase Muconate Lactonizing
AYN27_RS12550	COG1063	alcohol dehydrogenase
AYN27_RS12560	COG0582	viral genome integration into host DNA
AYN27_RS12575	COG3436	PFAM IS66 Orf2 family protein
AYN27_RS12580	COG4372	Transposase
AYN27_RS12590	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AYN27_RS12620	COG1396	sequence-specific DNA binding
AYN27_RS12635	COG1846	Transcriptional regulator
AYN27_RS12690	COG3772	lysozyme
AYN27_RS12835	COG5301	cellulose 1,4-beta-cellobiosidase activity
AYN27_RS12930	COG1607	acyl-coa hydrolase
AYN27_RS12950	COG3047	cAMP biosynthetic process
AYN27_RS12955	COG0582	viral genome integration into host DNA
AYN27_RS12965	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AYN27_RS13005	COG1396	sequence-specific DNA binding
AYN27_RS13025	COG1846	Transcriptional regulator
AYN27_RS13060	COG1403	HNH endonuclease
AYN27_RS13065	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
AYN27_RS13115	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AYN27_RS13140	COG0477	Major facilitator Superfamily
AYN27_RS13145	COG0246	Mannitol dehydrogenase
AYN27_RS13155	COG1802	Transcriptional regulator
AYN27_RS13160	COG4221	oxidoreductase activity
AYN27_RS13170	COG0339	signal peptide processing
AYN27_RS13180	COG1546	Belongs to the CinA family
AYN27_RS13185	COG3111	PFAM Bacterial OB fold (BOF) protein
AYN27_RS13190	COG3706	GGDEF domain
AYN27_RS13200	COG2814	Major facilitator Superfamily
AYN27_RS13205	COG0697	spore germination
AYN27_RS13210	COG2188	Transcriptional regulator
AYN27_RS13220	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AYN27_RS13225	COG1447	Phosphotransferase system cellobiose-specific component IIA
AYN27_RS13235	COG2723	6-phospho-beta-galactosidase activity
AYN27_RS13245	COG4977	sequence-specific DNA binding
AYN27_RS13250	COG1846	Transcriptional regulator
AYN27_RS13275	COG0583	DNA-binding transcription factor activity
AYN27_RS13280	COG1012	belongs to the aldehyde dehydrogenase family
AYN27_RS13285	COG2066	Belongs to the glutaminase family
AYN27_RS13300	COG2199	diguanylate cyclase activity
AYN27_RS13320	COG3781	membrane
AYN27_RS13390	COG1396	sequence-specific DNA binding
AYN27_RS13395	COG3550	peptidyl-serine autophosphorylation
AYN27_RS13415	COG3539	Fimbrial protein
AYN27_RS13425	COG3188	usher protein
AYN27_RS13430	COG3539	Fimbrial protein
AYN27_RS13435	COG3539	Fimbrial protein
AYN27_RS13440	COG3539	Fimbrial protein
AYN27_RS13445	COG0243	molybdopterin cofactor binding
AYN27_RS13455	COG2207	Transcriptional regulator
AYN27_RS13460	COG3119	arylsulfatase activity
AYN27_RS13465	COG0641	radical SAM
AYN27_RS13470	COG4178	(ABC) transporter
AYN27_RS13475	COG4771	TonB-dependent receptor
AYN27_RS13480	COG0612	Peptidase, M16
AYN27_RS13485	COG0076	glutamate decarboxylase activity
AYN27_RS13490	COG0531	amino acid
AYN27_RS13495	COG1649	PFAM Uncharacterised BCR, COG1649
AYN27_RS13505	COG2202	Pas domain
AYN27_RS13505	COG2200	EAL domain
AYN27_RS13505	COG2199	diguanylate cyclase activity
AYN27_RS13510	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AYN27_RS13515	COG0747	negative chemotaxis
AYN27_RS13520	COG0601	transmembrane transport
AYN27_RS13525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AYN27_RS13530	COG0444	Belongs to the ABC transporter superfamily
AYN27_RS13535	COG4608	Belongs to the ABC transporter superfamily
AYN27_RS13540	COG1764	response to oxidative stress
AYN27_RS13565	COG1064	alcohol dehydrogenase
AYN27_RS13570	COG3093	addiction module antidote protein HigA
AYN27_RS13575	COG2864	formate dehydrogenase
AYN27_RS13580	COG0437	4 iron, 4 sulfur cluster binding
AYN27_RS13590	COG0697	spore germination
AYN27_RS13595	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AYN27_RS13600	COG4886	Leucine-rich repeat (LRR) protein
AYN27_RS13605	COG2223	nitrite transmembrane transporter activity
AYN27_RS13610	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AYN27_RS13615	COG1140	nitrate reductase beta subunit
AYN27_RS13620	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AYN27_RS13625	COG2181	nitrate reductase activity
AYN27_RS13630	COG0384	phenazine biosynthesis protein PhzF
AYN27_RS13635	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AYN27_RS13640	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AYN27_RS13670	COG3209	COG3209 Rhs family protein
AYN27_RS13685	COG0625	glutathione transferase activity
AYN27_RS13695	COG3391	amine dehydrogenase activity
AYN27_RS13710	COG4772	TonB-dependent receptor
AYN27_RS13715	COG1802	Transcriptional regulator
AYN27_RS13720	COG2130	NADP-dependent
AYN27_RS13730	COG1247	-acetyltransferase
AYN27_RS13735	COG3238	Protein conserved in bacteria
AYN27_RS13770	COG1177	transmembrane transport
AYN27_RS13775	COG1176	ABC-type spermidine putrescine transport system, permease component I
AYN27_RS13780	COG3842	ATPase activity
AYN27_RS13785	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AYN27_RS13790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AYN27_RS13795	COG1598	PFAM Uncharacterised protein family UPF0150
AYN27_RS13800	COG1724	mRNA binding
AYN27_RS13810	COG0826	peptidase U32
AYN27_RS13815	COG1396	sequence-specific DNA binding
AYN27_RS13820	COG3135	benzoate transporter
AYN27_RS13825	COG0675	Transposase, IS605 OrfB family
AYN27_RS13840	COG0500	methyltransferase
AYN27_RS13845	COG1275	C4-dicarboxylate transporter malic acid transport protein
AYN27_RS13850	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AYN27_RS13855	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AYN27_RS13860	COG2841	Protein conserved in bacteria
AYN27_RS13880	COG5383	Protein conserved in bacteria
AYN27_RS13885	COG0583	DNA-binding transcription factor activity
AYN27_RS13890	COG0840	transmembrane signaling receptor activity
AYN27_RS13905	COG3038	cytochrome b561
AYN27_RS13910	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AYN27_RS13920	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AYN27_RS13925	COG1643	Atp-dependent helicase
AYN27_RS13935	COG2453	phosphatase
AYN27_RS13935	COG0671	phosphoesterase, PA-phosphatase related
AYN27_RS13940	COG2267	carboxylic ester hydrolase activity
AYN27_RS13945	COG4589	Belongs to the CDS family
AYN27_RS13950	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AYN27_RS13960	COG0667	Aldo Keto reductase
AYN27_RS13965	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AYN27_RS13970	COG3327	negative regulation of DNA-templated transcription, initiation
AYN27_RS13975	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AYN27_RS13980	COG0183	Belongs to the thiolase family
AYN27_RS13985	COG2050	protein possibly involved in aromatic compounds catabolism
AYN27_RS13990	COG1250	3-hydroxyacyl-CoA dehydrogenase
AYN27_RS13995	COG1024	Enoyl-CoA hydratase
AYN27_RS14000	COG1024	Enoyl-CoA hydratase
AYN27_RS14005	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AYN27_RS14010	COG2151	metal-sulfur cluster biosynthetic enzyme
AYN27_RS14015	COG3396	Phenylacetate-CoA oxygenase
AYN27_RS14020	COG3460	Phenylacetate-CoA oxygenase
AYN27_RS14025	COG3396	Phenylacetate-CoA oxygenase
AYN27_RS14030	COG2030	dehydratase
AYN27_RS14030	COG1012	belongs to the aldehyde dehydrogenase family
AYN27_RS14035	COG3733	amine oxidase
AYN27_RS14045	COG2207	Transcriptional regulator
AYN27_RS14050	COG3784	Protein of unknown function (DUF1318)
AYN27_RS14060	COG2911	Protein conserved in bacteria
AYN27_RS14065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AYN27_RS14070	COG3187	Heat shock protein
AYN27_RS14075	COG3042	response to heat
AYN27_RS14080	COG0674	pyruvate-flavodoxin oxidoreductase activity
AYN27_RS14080	COG1013	pyruvate-flavodoxin oxidoreductase activity
AYN27_RS14080	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AYN27_RS14080	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AYN27_RS14090	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AYN27_RS14095	COG0589	response to stress
AYN27_RS14120	COG5301	cellulose 1,4-beta-cellobiosidase activity
AYN27_RS14135	COG2032	superoxide dismutase activity
AYN27_RS14280	COG3772	lysozyme
AYN27_RS14380	COG1846	Transcriptional regulator
AYN27_RS14385	COG1484	DNA-dependent DNA replication
AYN27_RS14390	COG3756	Protein conserved in bacteria
AYN27_RS14450	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AYN27_RS14455	COG3723	Recombinational DNA repair protein, rece pathway
AYN27_RS14475	COG0582	viral genome integration into host DNA
AYN27_RS14485	COG0513	Belongs to the DEAD box helicase family
AYN27_RS14500	COG3706	GGDEF domain
AYN27_RS14505	COG2840	Smr protein MutS2
AYN27_RS14510	COG0583	DNA-binding transcription factor activity
AYN27_RS14520	COG1473	amidohydrolase
AYN27_RS14530	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AYN27_RS14535	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AYN27_RS14540	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AYN27_RS14545	COG0589	response to stress
AYN27_RS14550	COG3182	Iron-regulated membrane protein
AYN27_RS14555	COG0668	transmembrane transport
AYN27_RS14560	COG4166	transmembrane transport
AYN27_RS14565	COG0583	DNA-binding transcription factor activity
AYN27_RS14570	COG1073	alpha beta
AYN27_RS14575	COG1073	alpha beta
AYN27_RS14580	COG0702	epimerase
AYN27_RS14585	COG2866	Carboxypeptidase
AYN27_RS14590	COG4948	Mandelate Racemase Muconate Lactonizing
AYN27_RS14595	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AYN27_RS14600	COG3283	Transcriptional regulator of aromatic amino acids metabolism
AYN27_RS14610	COG3106	COG3106 Predicted ATPase
AYN27_RS14615	COG1609	Transcriptional regulator
AYN27_RS14625	COG3842	ATPase activity
AYN27_RS14630	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AYN27_RS14640	COG0673	inositol 2-dehydrogenase activity
AYN27_RS14645	COG1082	Xylose isomerase domain protein TIM barrel
AYN27_RS14650	COG1063	alcohol dehydrogenase
AYN27_RS14655	COG0395	ABC-type sugar transport system, permease component
AYN27_RS14660	COG1175	transmembrane transport
AYN27_RS14665	COG1653	transport
AYN27_RS14675	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AYN27_RS14685	COG1983	PspC domain protein
AYN27_RS14695	COG1842	Phage shock protein A
AYN27_RS14700	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AYN27_RS14705	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AYN27_RS14710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AYN27_RS14715	COG1012	belongs to the aldehyde dehydrogenase family
AYN27_RS14725	COG1396	sequence-specific DNA binding
AYN27_RS14725	COG1917	Cupin 2, conserved barrel domain protein
AYN27_RS14730	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AYN27_RS14735	COG0174	glutamine synthetase
AYN27_RS14740	COG0531	amino acid
AYN27_RS14755	COG4166	transmembrane transport
AYN27_RS14760	COG4168	peptide transport system, permease
AYN27_RS14765	COG4171	peptide transport system, permease
AYN27_RS14770	COG4172	Belongs to the ABC transporter superfamily
AYN27_RS14775	COG4172	Belongs to the ABC transporter superfamily
AYN27_RS14780	COG2852	Protein conserved in bacteria
AYN27_RS14785	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AYN27_RS14790	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AYN27_RS14790	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AYN27_RS14805	COG5001	Diguanylate cyclase
AYN27_RS14825	COG1349	DNA-binding transcription factor activity
AYN27_RS14835	COG0023	Translation Initiation Factor
AYN27_RS14845	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AYN27_RS14850	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AYN27_RS14855	COG0671	phosphoesterase, PA-phosphatase related
AYN27_RS14865	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AYN27_RS14885	COG0583	DNA-binding transcription factor activity
AYN27_RS14895	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AYN27_RS14910	COG0616	signal peptide processing
AYN27_RS14915	COG1028	Short-chain dehydrogenase reductase Sdr
AYN27_RS14920	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
AYN27_RS14925	COG1187	pseudouridine synthase activity
AYN27_RS14930	COG0009	L-threonylcarbamoyladenylate synthase
AYN27_RS14935	COG0613	PHP domain protein
AYN27_RS14945	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AYN27_RS14950	COG0512	Glutamine amidotransferase of anthranilate synthase
AYN27_RS14950	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AYN27_RS14955	COG0134	indole-3-glycerol-phosphate synthase activity
AYN27_RS14955	COG0135	phosphoribosylanthranilate isomerase activity
AYN27_RS14970	COG3729	General stress protein
AYN27_RS14975	COG3685	Protein conserved in bacteria
AYN27_RS14980	COG3685	Protein conserved in bacteria
AYN27_RS15015	COG5301	cellulose 1,4-beta-cellobiosidase activity
AYN27_RS15090	COG0740	serine-type endopeptidase activity
AYN27_RS15120	COG3772	lysozyme
AYN27_RS15175	COG0484	heat shock protein binding
AYN27_RS15180	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
AYN27_RS15185	COG1403	HNH endonuclease
AYN27_RS15235	COG1846	Transcriptional regulator
AYN27_RS15255	COG2350	Protein conserved in bacteria
AYN27_RS15260	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AYN27_RS15280	COG4608	Belongs to the ABC transporter superfamily
AYN27_RS15285	COG0444	Belongs to the ABC transporter superfamily
AYN27_RS15290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AYN27_RS15295	COG0601	transmembrane transport
AYN27_RS15300	COG4166	transmembrane transport
AYN27_RS15310	COG2095	MarC family integral membrane protein
AYN27_RS15315	COG1012	belongs to the aldehyde dehydrogenase family
AYN27_RS15315	COG1454	alcohol dehydrogenase
AYN27_RS15325	COG1435	thymidine kinase activity
AYN27_RS15335	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AYN27_RS15340	COG0745	RESPONSE REGULATOR receiver
AYN27_RS15345	COG1752	Esterase of the alpha-beta hydrolase superfamily
AYN27_RS15355	COG0788	formyltetrahydrofolate deformylase activity
AYN27_RS15380	COG2181	nitrate reductase activity
AYN27_RS15385	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AYN27_RS15390	COG1140	nitrate reductase beta subunit
AYN27_RS15395	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AYN27_RS15400	COG2223	nitrite transmembrane transporter activity
AYN27_RS15410	COG3850	Histidine kinase
AYN27_RS15415	COG4932	domain protein
AYN27_RS15420	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AYN27_RS15425	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AYN27_RS15430	COG4572	Cation transport regulator
AYN27_RS15435	COG0387	Pfam Sodium calcium exchanger
AYN27_RS15460	COG2912	Transglutaminase-like superfamily
AYN27_RS15465	COG3094	Invasion gene expression up-regulator, SirB
AYN27_RS15470	COG2890	protein-(glutamine-N5) methyltransferase activity
AYN27_RS15500	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AYN27_RS15510	COG0659	secondary active sulfate transmembrane transporter activity
AYN27_RS15525	COG0012	GTP binding
AYN27_RS15540	COG3468	outer membrane autotransporter barrel domain protein
AYN27_RS15545	COG3284	Transcriptional regulator
AYN27_RS15550	COG2376	Dihydroxyacetone kinase
AYN27_RS15555	COG1461	Dihydroxyacetone kinase
AYN27_RS15560	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AYN27_RS15560	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN27_RS15560	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
AYN27_RS15585	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
AYN27_RS15600	COG1619	proteins homologs of microcin C7 resistance protein MccF
AYN27_RS15615	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AYN27_RS15625	COG2719	SpoVR family
AYN27_RS15650	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AYN27_RS15665	COG0179	Fumarylacetoacetate (FAA) hydrolase
AYN27_RS15700	COG2894	cell division
AYN27_RS15760	COG2200	EAL domain
AYN27_RS15785	COG2200	EAL domain
AYN27_RS15790	COG0789	Transcriptional regulator
AYN27_RS15795	COG5562	phage envelope protein
AYN27_RS15805	COG0538	isocitrate dehydrogenase activity
AYN27_RS15810	COG1187	pseudouridine synthase activity
AYN27_RS15830	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AYN27_RS15840	COG2205	protein histidine kinase activity
AYN27_RS15845	COG2850	peptidyl-arginine hydroxylation
AYN27_RS15890	COG3328	transposase activity
AYN27_RS15910	COG5301	cellulose 1,4-beta-cellobiosidase activity
AYN27_RS15945	COG1185	polyribonucleotide nucleotidyltransferase activity
AYN27_RS16050	COG3772	lysozyme
AYN27_RS16105	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
AYN27_RS16110	COG1403	HNH endonuclease
AYN27_RS16140	COG1846	Transcriptional regulator
AYN27_RS16200	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AYN27_RS16210	COG0582	viral genome integration into host DNA
AYN27_RS16215	COG1177	transmembrane transport
AYN27_RS16220	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AYN27_RS16230	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AYN27_RS16235	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AYN27_RS16245	COG4591	ABC-type transport system involved in lipoprotein release permease component
AYN27_RS16250	COG1136	(ABC) transporter
AYN27_RS16255	COG4591	ABC-type transport system involved in lipoprotein release permease component
AYN27_RS16260	COG4763	Acyl-transferase
AYN27_RS16265	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AYN27_RS16270	COG1388	LysM domain
AYN27_RS16270	COG1376	ErfK ybiS ycfS ynhG family protein
AYN27_RS16280	COG1309	transcriptional regulator
AYN27_RS16285	COG3134	Outer membrane lipoprotein
AYN27_RS16295	COG1252	NADH dehydrogenase
AYN27_RS16315	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
AYN27_RS16320	COG5633	Lipoprotein
AYN27_RS16325	COG0537	adenosine 5'-monophosphoramidase activity
AYN27_RS16330	COG4773	Receptor
AYN27_RS16335	COG1263	PTS System
AYN27_RS16335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AYN27_RS16340	COG0084	hydrolase, TatD family'
AYN27_RS16345	COG0470	DNA polymerase III
AYN27_RS16355	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AYN27_RS16360	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AYN27_RS16365	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AYN27_RS16375	COG1028	Short-chain dehydrogenase reductase Sdr
AYN27_RS16380	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AYN27_RS16400	COG1399	metal-binding, possibly nucleic acid-binding protein
AYN27_RS16405	COG0424	maF-like protein
AYN27_RS16410	COG0564	pseudouridine synthase activity
AYN27_RS16420	COG1530	ribonuclease E activity
AYN27_RS16425	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AYN27_RS16430	COG1256	bacterial-type flagellum assembly
AYN27_RS16435	COG3951	Flagellar rod assembly protein muramidase FlgJ
AYN27_RS16435	COG1705	Flagellar rod assembly protein muramidase FlgJ
AYN27_RS16450	COG4786	Flagellar basal body rod
AYN27_RS16455	COG4787	bacterial-type flagellum-dependent cell motility
AYN27_RS16460	COG1749	Flagellar hook protein flgE
AYN27_RS16465	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AYN27_RS16470	COG1558	bacterial-type flagellum-dependent cell motility
AYN27_RS16475	COG1815	bacterial-type flagellum-dependent cell motility
AYN27_RS16480	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
AYN27_RS16485	COG2747	anti-sigma28 factor FlgM
AYN27_RS16490	COG3418	PFAM FlgN family protein
AYN27_RS16495	COG0728	peptidoglycan biosynthetic process
AYN27_RS16500	COG0673	inositol 2-dehydrogenase activity
AYN27_RS16510	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AYN27_RS16520	COG2999	glutathione oxidoreductase activity
AYN27_RS16560	COG3038	cytochrome b561
AYN27_RS16565	COG2353	YceI-like domain
AYN27_RS16575	COG1560	Kdo2-lipid A biosynthetic process
AYN27_RS16590	COG5645	(Lipo)protein
AYN27_RS16595	COG2943	transferase activity, transferring hexosyl groups
AYN27_RS16620	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AYN27_RS16625	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AYN27_RS16660	COG2197	response regulator
AYN27_RS16675	COG1462	curli production assembly transport component CsgG
AYN27_RS16685	COG3381	protein complex oligomerization
AYN27_RS16735	COG2003	Belongs to the UPF0758 family
AYN27_RS16805	COG1475	DNA binding
AYN27_RS16815	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AYN27_RS16820	COG2831	hemolysin activation secretion protein
AYN27_RS16920	COG4771	TonB-dependent receptor
AYN27_RS16985	COG1358	cellular component organization or biogenesis
AYN27_RS17025	COG4372	Transposase
AYN27_RS17030	COG3436	PFAM IS66 Orf2 family protein
AYN27_RS17085	COG0254	rRNA binding
AYN27_RS17115	COG0804	urea catabolic process
AYN27_RS17130	COG0829	nickel cation binding
AYN27_RS17145	COG2194	sulfuric ester hydrolase activity
AYN27_RS17150	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AYN27_RS17180	COG4372	Transposase
AYN27_RS17205	COG4983	Phage plasmid primase, P4 family domain protein
AYN27_RS17235	COG0582	viral genome integration into host DNA
AYN27_RS17255	COG1702	phosphate starvation-inducible protein PhoH
AYN27_RS17265	COG2822	iron ion transport
AYN27_RS17285	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AYN27_RS17300	COG0506	proline dehydrogenase activity
AYN27_RS17300	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AYN27_RS17300	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AYN27_RS17305	COG1309	transcriptional regulator
AYN27_RS17340	COG2233	PERMEase
AYN27_RS17345	COG3729	General stress protein
AYN27_RS17390	COG0243	molybdopterin cofactor binding
AYN27_RS17395	COG3005	denitrification pathway
AYN27_RS17400	COG0745	RESPONSE REGULATOR receiver
AYN27_RS17405	COG1879	ABC-type sugar transport system periplasmic component
AYN27_RS17410	COG2198	Histidine kinase
AYN27_RS17410	COG2205	protein histidine kinase activity
AYN27_RS17410	COG0784	Response regulator, receiver
AYN27_RS17415	COG0348	domain, Protein
AYN27_RS17435	COG1278	Cold shock
AYN27_RS17440	COG1278	Cold shock
AYN27_RS17460	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AYN27_RS17465	COG1596	polysaccharide export
AYN27_RS17470	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AYN27_RS17475	COG0489	protein tyrosine kinase activity
AYN27_RS17475	COG3206	protein involved in exopolysaccharide biosynthesis
AYN27_RS17490	COG1294	oxidase, subunit
AYN27_RS17495	COG1271	oxidase subunit
AYN27_RS17500	COG1773	rubredoxin
AYN27_RS17505	COG1999	signal sequence binding
AYN27_RS17510	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AYN27_RS17515	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
AYN27_RS17520	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AYN27_RS17525	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AYN27_RS17575	COG3772	lysozyme
AYN27_RS17630	COG2207	Transcriptional regulator
AYN27_RS17650	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
AYN27_RS17655	COG1403	HNH endonuclease
AYN27_RS17780	COG0670	Belongs to the BI1 family
AYN27_RS17785	COG2920	part of a sulfur-relay system
AYN27_RS17790	COG1254	Belongs to the acylphosphatase family
AYN27_RS17805	COG1832	CoA-binding protein
AYN27_RS17820	COG0210	DNA helicase
AYN27_RS17825	COG3304	Inner membrane component domain
AYN27_RS17830	COG1289	transmembrane transporter activity
AYN27_RS17835	COG3070	regulator of competence-specific genes
AYN27_RS17850	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AYN27_RS17850	COG2885	chlorophyll binding
AYN27_RS17860	COG1067	ATP-dependent peptidase activity
AYN27_RS17870	COG3130	regulation of translation
AYN27_RS17875	COG3009	Protein conserved in bacteria
AYN27_RS17880	COG3008	intermembrane lipid transfer
AYN27_RS17880	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AYN27_RS17885	COG2995	paraquat-inducible protein a
AYN27_RS17890	COG0488	(ABC) transporter
AYN27_RS17900	COG3217	Mosc domain protein beta barrel domain protein
AYN27_RS17900	COG0633	Ferredoxin
AYN27_RS17915	COG3121	Chaperone
AYN27_RS17920	COG3539	Fimbrial protein
AYN27_RS17925	COG3539	Fimbrial protein
AYN27_RS17930	COG3539	Fimbrial protein
AYN27_RS17935	COG3188	usher protein
AYN27_RS17940	COG3121	Chaperone
AYN27_RS17945	COG3539	Fimbrial protein
AYN27_RS17955	COG0431	NADPH-dependent FMN reductase
AYN27_RS17960	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AYN27_RS17970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AYN27_RS17980	COG0308	aminopeptidase N
AYN27_RS18005	COG1448	Aminotransferase
AYN27_RS18010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AYN27_RS18015	COG3108	Peptidase M15
AYN27_RS18025	COG2989	Protein conserved in bacteria
AYN27_RS18035	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
AYN27_RS18045	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AYN27_RS18050	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AYN27_RS18055	COG3173	Aminoglycoside phosphotransferase
AYN27_RS18070	COG3214	Protein conserved in bacteria
AYN27_RS18080	COG1132	(ABC) transporter
AYN27_RS18085	COG2333	competence protein COMEC
AYN27_RS18085	COG0658	competence protein
AYN27_RS18095	COG0539	negative regulation of cytoplasmic translation
AYN27_RS18105	COG0501	Belongs to the peptidase M48B family
AYN27_RS18120	COG2323	membrane
AYN27_RS18125	COG1944	ATP diphosphatase activity
AYN27_RS18130	COG2116	formate transmembrane transporter activity
AYN27_RS18135	COG1882	Formate acetyltransferase
AYN27_RS18140	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AYN27_RS18145	COG2249	NAD(P)H dehydrogenase (quinone) activity
AYN27_RS18150	COG0583	DNA-binding transcription factor activity
AYN27_RS18155	COG0531	amino acid
AYN27_RS18165	COG1335	isochorismatase
AYN27_RS18170	COG3302	dmso reductase anchor subunit
AYN27_RS18175	COG0437	4 iron, 4 sulfur cluster binding
AYN27_RS18180	COG0243	molybdopterin cofactor binding
AYN27_RS18190	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AYN27_RS18205	COG1522	sequence-specific DNA binding
AYN27_RS18215	COG0492	ferredoxin-NADP+ reductase activity
AYN27_RS18220	COG4988	ABC transporter
AYN27_RS18225	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AYN27_RS18245	COG0542	response to heat
AYN27_RS18255	COG1278	Cold shock
AYN27_RS18260	COG0577	efflux transmembrane transporter activity
AYN27_RS18260	COG1136	(ABC) transporter
AYN27_RS18265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYN27_RS18270	COG2990	Protein conserved in bacteria
AYN27_RS18275	COG3593	DNA synthesis involved in DNA repair
AYN27_RS18290	COG2431	L-lysine efflux transmembrane transporter activity
AYN27_RS18300	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AYN27_RS18305	COG0028	Belongs to the TPP enzyme family
AYN27_RS18310	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AYN27_RS18315	COG0702	epimerase
AYN27_RS18320	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AYN27_RS18325	COG3023	N-Acetylmuramoyl-L-alanine amidase
AYN27_RS18340	COG1126	abc transporter atp-binding protein
AYN27_RS18345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AYN27_RS18350	COG4215	(ABC) transporter
AYN27_RS18355	COG4160	amino acid transport
AYN27_RS18360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AYN27_RS18375	COG1177	transmembrane transport
AYN27_RS18380	COG1176	ABC-type spermidine putrescine transport system, permease component I
AYN27_RS18385	COG3842	ATPase activity
AYN27_RS18390	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AYN27_RS18410	COG0778	Nitroreductase
AYN27_RS18420	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AYN27_RS18435	COG3226	Transcriptional regulator
AYN27_RS18445	COG0561	phosphatase activity
AYN27_RS18455	COG2814	Major facilitator Superfamily
AYN27_RS18460	COG0671	phosphoesterase, PA-phosphatase related
AYN27_RS18465	COG1349	DNA-binding transcription factor activity
AYN27_RS18470	COG1686	Belongs to the peptidase S11 family
AYN27_RS18475	COG0625	glutathione transferase activity
AYN27_RS18480	COG2133	pyrroloquinoline quinone binding
AYN27_RS18495	COG2199	diguanylate cyclase activity
AYN27_RS18500	COG2200	EAL domain
AYN27_RS18525	COG1446	asparaginase
AYN27_RS18530	COG0303	'Molybdopterin
AYN27_RS18535	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AYN27_RS18540	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AYN27_RS18545	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AYN27_RS18550	COG1882	Formate acetyltransferase
AYN27_RS18555	COG0561	phosphatase activity
AYN27_RS18565	COG0488	(ABC) transporter
AYN27_RS18570	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AYN27_RS18610	COG1376	ErfK ybiS ycfS ynhG family protein
AYN27_RS18615	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AYN27_RS18620	COG1321	iron dependent repressor
AYN27_RS18630	COG2194	sulfuric ester hydrolase activity
AYN27_RS18635	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AYN27_RS18640	COG5006	permease, DMT superfamily
AYN27_RS18660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AYN27_RS18665	COG0765	amino acid transport
AYN27_RS18670	COG1126	abc transporter atp-binding protein
AYN27_RS18675	COG0668	transmembrane transport
AYN27_RS18690	COG4774	siderophore transport
AYN27_RS18700	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AYN27_RS18710	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AYN27_RS18715	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AYN27_RS18720	COG1199	ATP-dependent helicase activity
AYN27_RS18730	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
AYN27_RS18735	COG0513	Belongs to the DEAD box helicase family
AYN27_RS18740	COG1309	transcriptional regulator
AYN27_RS18750	COG1131	(ABC) transporter
AYN27_RS18755	COG0842	Transport permease protein
AYN27_RS18760	COG0842	Transport permease protein
AYN27_RS18770	COG3568	Endonuclease Exonuclease Phosphatase
AYN27_RS18775	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AYN27_RS18780	COG0392	lysyltransferase activity
AYN27_RS18785	COG0670	Belongs to the BI1 family
AYN27_RS18790	COG0670	Belongs to the BI1 family
AYN27_RS18795	COG0314	molybdopterin synthase activity
AYN27_RS18800	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AYN27_RS18810	COG0521	Mo-molybdopterin cofactor biosynthetic process
AYN27_RS18820	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AYN27_RS18830	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AYN27_RS18835	COG2226	methyltransferase
AYN27_RS18850	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AYN27_RS18855	COG1881	PFAM PEBP family protein
AYN27_RS18910	COG5301	cellulose 1,4-beta-cellobiosidase activity
AYN27_RS19100	COG3772	lysozyme
AYN27_RS19105	COG0582	viral genome integration into host DNA
AYN27_RS19110	COG4677	pectinesterase activity
AYN27_RS19115	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AYN27_RS19120	COG0471	metal ion transport
AYN27_RS19130	COG0583	DNA-binding transcription factor activity
AYN27_RS19140	COG0561	phosphatase activity
AYN27_RS19150	COG4149	molybdate abc transporter
AYN27_RS19155	COG0725	ABC transporter, periplasmic molybdate-binding protein
AYN27_RS19170	COG2005	Transcriptional regulator
AYN27_RS19170	COG3585	molybdate ion transport
AYN27_RS19175	COG1119	ATPase activity
AYN27_RS19180	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AYN27_RS19185	COG1085	galactose-1-phosphate uridylyltransferase
AYN27_RS19195	COG2017	converts alpha-aldose to the beta-anomer
AYN27_RS19205	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AYN27_RS19220	COG1230	cation diffusion facilitator family transporter
AYN27_RS19225	COG3201	nicotinamide mononucleotide transporter
AYN27_RS19275	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AYN27_RS19280	COG2885	chlorophyll binding
AYN27_RS19290	COG3064	Membrane
AYN27_RS19295	COG0848	biopolymer transport protein
AYN27_RS19300	COG0811	peptide transport
AYN27_RS19305	COG0824	Thioesterase
AYN27_RS19310	COG3790	cyd operon protein YbgE
AYN27_RS19315	COG4890	Cyd operon protein YbgT
AYN27_RS19320	COG1294	oxidase, subunit
AYN27_RS19325	COG1271	oxidase subunit
AYN27_RS19335	COG0383	alpha-mannosidase activity
AYN27_RS19340	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AYN27_RS19340	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AYN27_RS19340	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN27_RS19345	COG2188	Transcriptional regulator
AYN27_RS19350	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AYN27_RS19360	COG0508	dehydrogenase complex catalyzes the overall conversion of
AYN27_RS19365	COG0567	Dehydrogenase, E1 component
AYN27_RS19370	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AYN27_RS19375	COG1053	succinate dehydrogenase
AYN27_RS19380	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AYN27_RS19385	COG2009	succinate dehydrogenase
AYN27_RS19400	COG0372	Belongs to the citrate synthase family
AYN27_RS19405	COG3539	Fimbrial protein
AYN27_RS19410	COG3188	usher protein
AYN27_RS19415	COG3121	Chaperone
AYN27_RS19420	COG3539	Fimbrial protein
AYN27_RS19425	COG3180	Ammonia monooxygenase
AYN27_RS19440	COG1984	allophanate hydrolase subunit 2
AYN27_RS19445	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AYN27_RS19450	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AYN27_RS19460	COG0415	Belongs to the DNA photolyase family
AYN27_RS19465	COG3272	Protein of unknown function (DUF1722)
AYN27_RS19490	COG3209	COG3209 Rhs family protein
AYN27_RS19520	COG2205	protein histidine kinase activity
AYN27_RS19525	COG0745	RESPONSE REGULATOR receiver
AYN27_RS19540	COG1982	Orn Lys Arg decarboxylase major
AYN27_RS19545	COG0531	amino acid
AYN27_RS19550	COG0033	Phosphoglucomutase
AYN27_RS19555	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AYN27_RS19560	COG0596	Alpha beta hydrolase
AYN27_RS19570	COG0716	FMN binding
AYN27_RS19580	COG0735	belongs to the Fur family
AYN27_RS19605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AYN27_RS19605	COG2190	(PTS) system
AYN27_RS19605	COG1263	PTS System
AYN27_RS19615	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AYN27_RS19620	COG1940	carbohydrate kinase activity
AYN27_RS19620	COG1846	Transcriptional regulator
AYN27_RS19625	COG0647	UMP catabolic process
AYN27_RS19635	COG0367	asparagine synthase
AYN27_RS19680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AYN27_RS19690	COG1702	phosphate starvation-inducible protein PhoH
AYN27_RS19700	COG4535	Mg2 and Co2 transporter CorC
AYN27_RS19705	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AYN27_RS19720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AYN27_RS19725	COG0765	amino acid transport
AYN27_RS19730	COG0765	amino acid transport
AYN27_RS19735	COG1126	abc transporter atp-binding protein
AYN27_RS19745	COG0443	Heat shock 70 kDa protein
AYN27_RS19750	COG2214	Heat shock protein DnaJ domain protein
AYN27_RS19760	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AYN27_RS19765	COG2214	Heat shock protein DnaJ domain protein
AYN27_RS19775	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AYN27_RS19780	COG2888	peptidyl-tyrosine sulfation
AYN27_RS19795	COG1466	dna polymerase III delta subunit
AYN27_RS19805	COG0406	alpha-ribazole phosphatase activity
AYN27_RS19810	COG0799	negative regulation of ribosome biogenesis
AYN27_RS19820	COG0768	penicillin binding
AYN27_RS19825	COG0772	Belongs to the SEDS family
AYN27_RS19830	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AYN27_RS19835	COG1686	Belongs to the peptidase S11 family
AYN27_RS19855	COG0583	DNA-binding transcription factor activity
AYN27_RS19870	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AYN27_RS19875	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AYN27_RS19900	COG3069	C4-dicarboxylate transmembrane transporter activity
AYN27_RS19905	COG4565	transcriptional regulatory protein
AYN27_RS19910	COG3290	protein histidine kinase activity
AYN27_RS19915	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
AYN27_RS19925	COG2301	Belongs to the HpcH HpaI aldolase family
AYN27_RS19930	COG3051	citrate lyase alpha subunit
AYN27_RS19945	COG0471	metal ion transport
AYN27_RS19950	COG3719	Belongs to the RNase T2 family
AYN27_RS19960	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AYN27_RS19970	COG1063	alcohol dehydrogenase
AYN27_RS19975	COG0589	response to stress
AYN27_RS19980	COG3634	alkyl hydroperoxide reductase activity
AYN27_RS19985	COG0450	alkyl hydroperoxide reductase
AYN27_RS19990	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AYN27_RS19995	COG0583	DNA-binding transcription factor activity
AYN27_RS20000	COG3969	phosphoadenosine phosphosulfate
AYN27_RS20010	COG0436	Aminotransferase
AYN27_RS20015	COG0371	Dehydrogenase
AYN27_RS20020	COG2879	small protein
AYN27_RS20025	COG1966	Carbon starvation protein
AYN27_RS20030	COG2050	protein possibly involved in aromatic compounds catabolism
AYN27_RS20035	COG1028	Short-chain dehydrogenase reductase Sdr
AYN27_RS20040	COG3433	isochorismatase activity
AYN27_RS20040	COG1535	isochorismatase
AYN27_RS20045	COG1021	2,3-dihydroxybenzoate-AMP ligase
AYN27_RS20050	COG1169	isochorismate synthase
AYN27_RS20060	COG4592	Periplasmic binding protein
AYN27_RS20070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AYN27_RS20075	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AYN27_RS20080	COG1120	ATPase activity
AYN27_RS20085	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
AYN27_RS20090	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AYN27_RS20090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AYN27_RS20095	COG3251	PFAM MbtH domain protein
AYN27_RS20100	COG2382	esterase
AYN27_RS20110	COG4771	TonB-dependent receptor
AYN27_RS20115	COG2977	Belongs to the P-Pant transferase superfamily
AYN27_RS20150	COG2315	Protein conserved in bacteria
AYN27_RS20155	COG0778	Nitroreductase
AYN27_RS20160	COG0668	transmembrane transport
AYN27_RS20165	COG1113	amino acid transport
AYN27_RS20170	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AYN27_RS20175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYN27_RS20180	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYN27_RS20185	COG1538	Outer membrane efflux protein
AYN27_RS20195	COG0745	RESPONSE REGULATOR receiver
AYN27_RS20200	COG5002	protein histidine kinase activity
AYN27_RS20205	COG3501	Rhs element vgr protein
AYN27_RS20215	COG4104	PAAR repeat-containing protein
AYN27_RS20215	COG3209	COG3209 Rhs family protein
AYN27_RS20230	COG3209	COG3209 Rhs family protein
AYN27_RS20230	COG4104	PAAR repeat-containing protein
AYN27_RS20235	COG5433	transposase activity
AYN27_RS20240	COG1215	transferase activity, transferring glycosyl groups
AYN27_RS20245	COG4783	chaperone-mediated protein folding
AYN27_RS20260	COG2207	Transcriptional regulator
AYN27_RS20275	COG4571	Outer membrane protease
AYN27_RS20290	COG0500	methyltransferase
AYN27_RS20300	COG1196	nuclear chromosome segregation
AYN27_RS20375	COG2197	response regulator
AYN27_RS20380	COG3539	Fimbrial protein
AYN27_RS20390	COG3188	usher protein
AYN27_RS20395	COG3121	Chaperone
AYN27_RS20400	COG3539	Fimbrial protein
AYN27_RS20410	COG2501	S4 domain
AYN27_RS20415	COG1988	membrane-bound metal-dependent
AYN27_RS20425	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AYN27_RS20440	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AYN27_RS20445	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AYN27_RS20450	COG0549	Belongs to the carbamate kinase family
AYN27_RS20460	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AYN27_RS20465	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AYN27_RS20470	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AYN27_RS20475	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AYN27_RS20480	COG3257	ureidoglycine aminohydrolase activity
AYN27_RS20485	COG1929	Belongs to the glycerate kinase type-1 family
AYN27_RS20490	COG2233	PERMEase
AYN27_RS20500	COG1953	Uracil, thiamine, allantoin
AYN27_RS20505	COG2084	Dehydrogenase
AYN27_RS20510	COG3622	Belongs to the hyi family
AYN27_RS20515	COG3960	tartronate-semialdehyde synthase activity
AYN27_RS20520	COG1414	Transcriptional regulator
AYN27_RS20530	COG0583	DNA-binding transcription factor activity
AYN27_RS20560	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AYN27_RS20565	COG4181	ATPase activity
AYN27_RS20570	COG2755	lipolytic protein G-D-S-L family
AYN27_RS20575	COG0300	oxidoreductase activity
AYN27_RS20580	COG3118	belongs to the thioredoxin family
AYN27_RS20585	COG0390	transport system, permease component
AYN27_RS20590	COG4619	ABC transporter
AYN27_RS20595	COG0330	HflC and HflK could
AYN27_RS20600	COG1585	Membrane protein implicated in regulation of membrane protease activity
AYN27_RS20605	COG0789	Transcriptional regulator
AYN27_RS20610	COG0531	amino acid
AYN27_RS20620	COG2217	Heavy metal translocating P-type atpase
AYN27_RS20625	COG3093	addiction module antidote protein HigA
AYN27_RS20635	COG3735	TraB family
AYN27_RS20645	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AYN27_RS20650	COG0737	Belongs to the 5'-nucleotidase family
AYN27_RS20660	COG2223	nitrite transmembrane transporter activity
AYN27_RS20665	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AYN27_RS20665	COG4651	solute:proton antiporter activity
AYN27_RS20670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AYN27_RS20710	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AYN27_RS20725	COG2832	Protein of unknown function (DUF454)
AYN27_RS20730	COG3923	Primosomal replication protein n
AYN27_RS20760	COG3264	Mechanosensitive ion channel
AYN27_RS20760	COG1196	nuclear chromosome segregation
AYN27_RS20770	COG1309	transcriptional regulator
AYN27_RS20775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYN27_RS20780	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AYN27_RS20795	COG0110	maltose O-acetyltransferase activity
AYN27_RS20805	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AYN27_RS20810	COG5507	3-demethylubiquinone-9 3-methyltransferase
AYN27_RS20820	COG3695	enzyme binding
AYN27_RS20825	COG3126	Type III secretion system lipoprotein chaperone (YscW)
AYN27_RS20830	COG1946	Acyl-CoA thioesterase
AYN27_RS20835	COG0004	ammonium transporteR
AYN27_RS20840	COG0347	Belongs to the P(II) protein family
AYN27_RS20845	COG1132	(ABC) transporter
AYN27_RS20850	COG1132	(ABC) transporter
AYN27_RS20855	COG1522	sequence-specific DNA binding
AYN27_RS20865	COG4533	DNA binding
AYN27_RS20875	COG0824	Thioesterase
AYN27_RS20880	COG1555	photosystem II stabilization
AYN27_RS20885	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AYN27_RS20890	COG0776	regulation of translation
AYN27_RS20895	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AYN27_RS20920	COG0271	Belongs to the BolA IbaG family
AYN27_RS20925	COG3056	Lipoprotein
AYN27_RS20930	COG2223	nitrite transmembrane transporter activity
AYN27_RS20935	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AYN27_RS20940	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AYN27_RS20945	COG1845	cytochrome c oxidase, subunit III
AYN27_RS20950	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AYN27_RS20975	COG2814	Major facilitator Superfamily
AYN27_RS20985	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AYN27_RS20990	COG0693	protein deglycase activity
AYN27_RS21005	COG0142	geranyltranstransferase activity
AYN27_RS21020	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AYN27_RS21025	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AYN27_RS21040	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AYN27_RS21040	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AYN27_RS21050	COG4238	major outer membrane lipoprotein
AYN27_RS21055	COG3248	Nucleoside-binding outer membrane protein
AYN27_RS21060	COG1403	HNH endonuclease
AYN27_RS21065	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AYN27_RS21070	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AYN27_RS21075	COG1862	Preprotein translocase
AYN27_RS21095	COG0366	Alpha amylase catalytic
AYN27_RS21100	COG1113	amino acid transport
AYN27_RS21105	COG1114	Component of the transport system for branched-chain amino acids
AYN27_RS21110	COG5002	protein histidine kinase activity
AYN27_RS21115	COG0745	RESPONSE REGULATOR receiver
AYN27_RS21120	COG0420	3'-5' exonuclease activity
AYN27_RS21125	COG0419	ATPase involved in DNA repair
AYN27_RS21130	COG2814	Major facilitator Superfamily
AYN27_RS21135	COG1940	carbohydrate kinase activity
AYN27_RS21160	COG4126	flavin adenine dinucleotide binding
AYN27_RS21185	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AYN27_RS21190	COG3706	GGDEF domain
AYN27_RS21200	COG1785	Belongs to the alkaline phosphatase family
AYN27_RS21215	COG1181	Belongs to the D-alanine--D-alanine ligase family
AYN27_RS21240	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AYN27_RS21250	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AYN27_RS21255	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AYN27_RS21260	COG3468	outer membrane autotransporter barrel domain protein
AYN27_RS21275	COG0113	porphobilinogen synthase activity
AYN27_RS21280	COG2175	clavaminate synthase activity
AYN27_RS21290	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AYN27_RS21295	COG4521	taurine ABC transporter
AYN27_RS21305	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AYN27_RS21310	COG1215	transferase activity, transferring glycosyl groups
AYN27_RS21340	COG3122	Protein conserved in bacteria
AYN27_RS21345	COG2814	Major facilitator Superfamily
AYN27_RS21380	COG1414	Transcriptional regulator
AYN27_RS21385	COG1609	Transcriptional regulator
AYN27_RS21395	COG3250	beta-galactosidase activity
AYN27_RS21400	COG2223	nitrite transmembrane transporter activity
AYN27_RS21405	COG2807	transmembrane transport
AYN27_RS21415	COG0288	reversible hydration of carbon dioxide
AYN27_RS21420	COG0583	DNA-binding transcription factor activity
AYN27_RS21425	COG0402	S-adenosylhomocysteine deaminase activity
AYN27_RS21430	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AYN27_RS21435	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AYN27_RS21440	COG2079	MmgE PrpD family protein
AYN27_RS21445	COG0372	Belongs to the citrate synthase family
AYN27_RS21450	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AYN27_RS21455	COG3829	transcription factor binding
AYN27_RS21465	COG1280	lysine exporter protein (LysE YggA)
AYN27_RS21480	COG1064	alcohol dehydrogenase
AYN27_RS21490	COG1172	Belongs to the binding-protein-dependent transport system permease family
AYN27_RS21495	COG1129	ABC transporter
AYN27_RS21500	COG1879	ABC-type sugar transport system periplasmic component
AYN27_RS21510	COG0402	S-adenosylhomocysteine deaminase activity
AYN27_RS21515	COG0549	Belongs to the carbamate kinase family
AYN27_RS21520	COG1304	FMN binding
AYN27_RS21525	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AYN27_RS21535	COG0666	response to abiotic stimulus
AYN27_RS21550	COG0583	DNA-binding transcription factor activity
AYN27_RS21555	COG2200	EAL domain
AYN27_RS21555	COG2771	luxR family
AYN27_RS21565	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AYN27_RS21605	COG1556	Lactate utilization protein
AYN27_RS21610	COG1139	Iron-sulfur cluster binding protein
AYN27_RS21615	COG0247	lactate metabolic process
AYN27_RS21620	COG2207	Transcriptional regulator
AYN27_RS21625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AYN27_RS21660	COG0582	viral genome integration into host DNA
AYN27_RS21685	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AYN27_RS21705	COG2195	Cleaves the N-terminal amino acid of tripeptides
AYN27_RS21710	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AYN27_RS21715	COG1690	Belongs to the RtcB family
AYN27_RS21725	COG0454	-acetyltransferase
AYN27_RS21740	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AYN27_RS21745	COG1191	sigma factor activity
AYN27_RS21770	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AYN27_RS21780	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AYN27_RS21795	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AYN27_RS21820	COG4786	Flagellar basal body rod
AYN27_RS21825	COG4787	bacterial-type flagellum-dependent cell motility
AYN27_RS21830	COG1749	Flagellar hook protein flgE
AYN27_RS21840	COG1558	bacterial-type flagellum-dependent cell motility
AYN27_RS21845	COG1815	bacterial-type flagellum-dependent cell motility
AYN27_RS21875	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AYN27_RS21895	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AYN27_RS21905	COG1677	Flagellar hook-basal body complex protein FliE
AYN27_RS21930	COG1987	bacterial-type flagellum assembly
AYN27_RS21960	COG0791	NLP P60 protein
AYN27_RS21965	COG3077	Addiction module antitoxin, RelB DinJ family
AYN27_RS21970	COG3041	Addiction module toxin RelE StbE family
AYN27_RS21975	COG3034	peptidoglycan biosynthetic process
AYN27_RS21980	COG0121	glutamine amidotransferase
AYN27_RS21990	COG1960	acyl-CoA dehydrogenase activity
AYN27_RS22000	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AYN27_RS22020	COG3209	COG3209 Rhs family protein
AYN27_RS22115	COG3157	Type VI secretion system effector, Hcp
AYN27_RS22120	COG4104	PAAR repeat-containing protein
AYN27_RS22145	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AYN27_RS22155	COG2226	methyltransferase
AYN27_RS22165	COG0741	lytic transglycosylase activity
AYN27_RS22165	COG1388	LysM domain
AYN27_RS22170	COG2226	methyltransferase
AYN27_RS22180	COG0583	DNA-binding transcription factor activity
AYN27_RS22185	COG0656	L-ascorbic acid biosynthetic process
AYN27_RS22220	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AYN27_RS22225	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AYN27_RS22230	COG2011	ABC-type metal ion transport system permease component
AYN27_RS22235	COG1464	Belongs to the NlpA lipoprotein family
AYN27_RS22245	COG1720	tRNA m6t6A37 methyltransferase activity
AYN27_RS22260	COG3015	lipoprotein NlpE involved in copper resistance
AYN27_RS22265	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AYN27_RS22270	COG4681	YaeQ
AYN27_RS22280	COG4568	rho-dependent transcription termination
AYN27_RS22290	COG0346	lactoylglutathione lyase activity
AYN27_RS22295	COG1982	Orn Lys Arg decarboxylase major
AYN27_RS22305	COG0587	DNA-directed DNA polymerase activity
AYN27_RS22330	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AYN27_RS22335	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AYN27_RS22345	COG0750	zinc metalloprotease
AYN27_RS22350	COG0575	Belongs to the CDS family
AYN27_RS22360	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AYN27_RS22395	COG0024	Methionine aminopeptidase
AYN27_RS22410	COG1408	metallophosphoesterase
AYN27_RS22420	COG3835	regulator
AYN27_RS22425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AYN27_RS22445	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AYN27_RS22450	COG2860	membrane
AYN27_RS22470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AYN27_RS22475	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AYN27_RS22480	COG1120	ATPase activity
AYN27_RS22485	COG4774	siderophore transport
AYN27_RS22490	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AYN27_RS22500	COG1643	Atp-dependent helicase
AYN27_RS22505	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AYN27_RS22515	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AYN27_RS22525	COG0617	tRNA 3'-terminal CCA addition
AYN27_RS22530	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AYN27_RS22535	COG3539	Fimbrial protein
AYN27_RS22540	COG3121	Chaperone
AYN27_RS22545	COG3188	usher protein
AYN27_RS22550	COG3539	Fimbrial protein
AYN27_RS22555	COG3539	Fimbrial protein
AYN27_RS22560	COG3539	Fimbrial protein
AYN27_RS22580	COG5464	transposase or invertase
AYN27_RS22600	COG0726	polysaccharide deacetylase
AYN27_RS22605	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN27_RS22610	COG0842	Transport permease protein
AYN27_RS22615	COG1131	(ABC) transporter
AYN27_RS22620	COG0288	reversible hydration of carbon dioxide
AYN27_RS22625	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AYN27_RS22630	COG4993	Dehydrogenase
AYN27_RS22635	COG2132	Multicopper oxidase
AYN27_RS22660	COG1049	propionate catabolic process, 2-methylcitrate cycle
AYN27_RS22670	COG3064	Membrane
AYN27_RS22675	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AYN27_RS22680	COG0508	dehydrogenase complex catalyzes the overall conversion of
AYN27_RS22685	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AYN27_RS22695	COG2186	Transcriptional regulator
AYN27_RS22700	COG1113	amino acid transport
AYN27_RS22705	COG3725	Membrane protein required for beta-lactamase induction
AYN27_RS22710	COG3023	N-Acetylmuramoyl-L-alanine amidase
AYN27_RS22715	COG0157	Belongs to the NadC ModD family
AYN27_RS22725	COG4969	Belongs to the N-Me-Phe pilin family
AYN27_RS22730	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AYN27_RS22735	COG1459	type II secretion system
AYN27_RS22745	COG0237	dephospho-CoA kinase activity
AYN27_RS22760	COG0494	nUDIX hydrolase
AYN27_RS22780	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AYN27_RS22785	COG0849	cell division
AYN27_RS22790	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AYN27_RS22795	COG1181	Belongs to the D-alanine--D-alanine ligase family
AYN27_RS22810	COG0772	Belongs to the SEDS family
AYN27_RS22825	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AYN27_RS22830	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AYN27_RS22835	COG0768	penicillin binding
AYN27_RS22840	COG3116	cell division
AYN27_RS22865	COG1609	Transcriptional regulator
AYN27_RS22875	COG0440	acetolactate synthase activity
AYN27_RS22880	COG0028	Belongs to the TPP enzyme family
AYN27_RS22885	COG0583	DNA-binding transcription factor activity
AYN27_RS22900	COG0473	3-isopropylmalate dehydrogenase activity
AYN27_RS22915	COG2814	Major facilitator Superfamily
AYN27_RS22930	COG4143	(ABC) transporter
AYN27_RS22935	COG1178	ABC-type Fe3 transport system permease component
AYN27_RS22945	COG0586	Pfam SNARE associated Golgi protein
AYN27_RS22950	COG4977	sequence-specific DNA binding
AYN27_RS22970	COG0235	Class ii aldolase
AYN27_RS22975	COG0417	DNA replication proofreading
AYN27_RS22985	COG0564	pseudouridine synthase activity
AYN27_RS22990	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AYN27_RS22995	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AYN27_RS23000	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AYN27_RS23040	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AYN27_RS23055	COG2271	Major facilitator Superfamily
AYN27_RS23060	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AYN27_RS23065	COG0644	oxidoreductase
AYN27_RS23120	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AYN27_RS23125	COG0505	Belongs to the CarA family
AYN27_RS23150	COG1047	Peptidyl-prolyl cis-trans
AYN27_RS23165	COG0196	riboflavin kinase activity
AYN27_RS23195	COG0583	DNA-binding transcription factor activity
AYN27_RS23225	COG4735	regulation of single-species biofilm formation
AYN27_RS23230	COG1584	GPR1 FUN34 yaaH family protein
AYN27_RS23235	COG0521	Mo-molybdopterin cofactor biosynthetic process
AYN27_RS23240	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AYN27_RS23245	COG1115	amino acid carrier protein
AYN27_RS23260	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AYN27_RS23270	COG0527	aspartate kinase activity
AYN27_RS23270	COG0460	homoserine dehydrogenase
AYN27_RS23280	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AYN27_RS23295	COG0745	RESPONSE REGULATOR receiver
AYN27_RS23300	COG4452	Inner membrane protein CreD
AYN27_RS23305	COG2205	protein histidine kinase activity
AYN27_RS23310	COG0745	RESPONSE REGULATOR receiver
AYN27_RS23315	COG3045	CreA protein
AYN27_RS23320	COG3708	Transcriptional regulator
AYN27_RS23320	COG2207	Transcriptional regulator
AYN27_RS23340	COG0741	lytic transglycosylase activity
AYN27_RS23350	COG0488	(ABC) transporter
AYN27_RS23355	COG3172	ATPase kinase involved in NAD metabolism
AYN27_RS23355	COG1056	cytidyltransferase-related domain
AYN27_RS23360	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AYN27_RS23365	COG0560	Phosphoserine phosphatase
AYN27_RS23370	COG3726	membrane protein affecting hemolysin expression
AYN27_RS23400	COG1328	CTP reductase activity
AYN27_RS23405	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AYN27_RS23410	COG0084	hydrolase, TatD family'
AYN27_RS23415	COG4667	esterase of the alpha-beta hydrolase superfamily
AYN27_RS23425	COG2823	Periplasmic or secreted lipoprotein
AYN27_RS23435	COG1011	Hydrolase
AYN27_RS23440	COG0456	acetyltransferase
AYN27_RS23445	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
AYN27_RS23475	COG4114	ferric iron reductase
AYN27_RS23480	COG2197	response regulator
AYN27_RS23485	COG2197	response regulator
AYN27_RS23490	COG2966	Psort location CytoplasmicMembrane, score
AYN27_RS23505	COG1484	DNA-dependent DNA replication
AYN27_RS23520	COG1063	alcohol dehydrogenase
AYN27_RS23525	COG1802	Transcriptional regulator
AYN27_RS23530	COG2271	Major facilitator Superfamily
AYN27_RS23535	COG0840	transmembrane signaling receptor activity
AYN27_RS23540	COG1846	Transcriptional regulator
AYN27_RS23545	COG0179	Fumarylacetoacetate (FAA) hydrolase
AYN27_RS23550	COG1012	belongs to the aldehyde dehydrogenase family
AYN27_RS23555	COG3384	dioxygenase
AYN27_RS23565	COG3971	2-oxopent-4-enoate hydratase activity
AYN27_RS23585	COG2368	4-hydroxyphenylacetate
AYN27_RS23590	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AYN27_RS23600	COG1966	Carbon starvation protein
AYN27_RS23605	COG2879	small protein
AYN27_RS23610	COG0523	cobalamin synthesis protein
AYN27_RS23630	COG5457	Domain of unknown function (DUF1127)
AYN27_RS23635	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AYN27_RS23650	COG2814	Major facilitator Superfamily
AYN27_RS23655	COG2733	membrane
AYN27_RS23660	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
AYN27_RS23665	COG1924	4 iron, 4 sulfur cluster binding
AYN27_RS23680	COG0477	Major facilitator Superfamily
AYN27_RS23695	COG3366	ferrous iron transmembrane transporter activity
AYN27_RS23700	COG0700	Nucleoside recognition
AYN27_RS23705	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AYN27_RS23710	COG0583	DNA-binding transcription factor activity
AYN27_RS23730	COG2186	Transcriptional regulator
AYN27_RS23740	COG0246	Mannitol dehydrogenase
AYN27_RS23755	COG2610	gluconate transmembrane transporter activity
AYN27_RS23765	COG3539	Fimbrial protein
AYN27_RS23770	COG3539	Fimbrial protein
AYN27_RS23775	COG3539	Fimbrial protein
AYN27_RS23790	COG3121	Chaperone
AYN27_RS23795	COG3539	Fimbrial protein
AYN27_RS23810	COG4974	Belongs to the 'phage' integrase family
AYN27_RS23815	COG0582	viral genome integration into host DNA
AYN27_RS23830	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AYN27_RS23915	COG0582	viral genome integration into host DNA
AYN27_RS23925	COG1064	alcohol dehydrogenase
AYN27_RS23935	COG0795	lipopolysaccharide-transporting ATPase activity
AYN27_RS23940	COG0795	lipopolysaccharide-transporting ATPase activity
AYN27_RS23950	COG2927	DNA polymerase III (CHI subunit)
AYN27_RS23955	COG0525	valine-tRNA ligase activity
AYN27_RS23960	COG4269	membrane
AYN27_RS23965	COG0456	acetyltransferase
AYN27_RS23970	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
AYN27_RS23990	COG2731	YhcH YjgK YiaL family protein
AYN27_RS23995	COG1309	transcriptional regulator
AYN27_RS24000	COG1028	Short-chain dehydrogenase reductase Sdr
AYN27_RS24005	COG0251	oxidation-reduction process
AYN27_RS24030	COG0251	oxidation-reduction process
AYN27_RS24035	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AYN27_RS24045	COG1609	Transcriptional regulator
AYN27_RS24050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AYN27_RS24050	COG1263	PTS System
AYN27_RS24055	COG0366	Alpha amylase catalytic
AYN27_RS24060	COG1328	CTP reductase activity
AYN27_RS24065	COG0602	queuosine metabolic process
AYN27_RS24070	COG3783	Cytochrome b(562)
AYN27_RS24075	COG0312	modulator of DNA gyrase
AYN27_RS24085	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AYN27_RS24095	COG1172	Belongs to the binding-protein-dependent transport system permease family
AYN27_RS24100	COG1172	Belongs to the binding-protein-dependent transport system permease family
AYN27_RS24105	COG1129	ABC transporter
AYN27_RS24110	COG1879	ABC-type sugar transport system periplasmic component
AYN27_RS24115	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AYN27_RS24120	COG2337	Toxic component of a toxin-antitoxin (TA) module
AYN27_RS24125	COG2336	PFAM SpoVT AbrB
AYN27_RS24130	COG2105	PFAM AIG2 family protein
AYN27_RS24135	COG2911	Protein conserved in bacteria
AYN27_RS24140	COG0729	surface antigen
AYN27_RS24155	COG1253	flavin adenine dinucleotide binding
AYN27_RS24165	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AYN27_RS24170	COG1218	3'(2'),5'-bisphosphate nucleotidase
AYN27_RS24175	COG0737	Belongs to the 5'-nucleotidase family
AYN27_RS24180	COG1733	regulation of RNA biosynthetic process
AYN27_RS24185	COG0702	epimerase
AYN27_RS24190	COG0697	spore germination
AYN27_RS24210	COG1113	amino acid transport
AYN27_RS24215	COG0545	Peptidyl-prolyl cis-trans isomerase
AYN27_RS24225	COG3061	Opacity-associated protein A
AYN27_RS24235	COG0675	Transposase, IS605 OrfB family
AYN27_RS24275	COG3436	PFAM IS66 Orf2 family protein
AYN27_RS24295	COG0582	viral genome integration into host DNA
AYN27_RS24305	COG1309	transcriptional regulator
AYN27_RS24320	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AYN27_RS24325	COG1027	Aspartate ammonia-lyase
AYN27_RS24330	COG3030	protein affecting phage T7 exclusion by the F plasmid
AYN27_RS24335	COG0531	amino acid
AYN27_RS24360	COG1509	lysine 2,3-aminomutase activity
AYN27_RS24370	COG5510	response to toxic substance
AYN27_RS24375	COG5510	response to toxic substance
AYN27_RS24380	COG2076	Multidrug Resistance protein
AYN27_RS24385	COG3040	lipid binding
AYN27_RS24390	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AYN27_RS24405	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AYN27_RS24410	COG1053	succinate dehydrogenase
AYN27_RS24420	COG0531	amino acid
AYN27_RS24435	COG3264	Mechanosensitive ion channel
AYN27_RS24435	COG1511	domain protein
AYN27_RS24480	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AYN27_RS24480	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AYN27_RS24485	COG0802	atpase or kinase
AYN27_RS24490	COG0860	N-Acetylmuramoyl-L-alanine amidase
AYN27_RS24510	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AYN27_RS24515	COG0330	HflC and HflK could
AYN27_RS24520	COG0330	HflC and HflK could
AYN27_RS24525	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AYN27_RS24540	COG0557	exoribonuclease II activity
AYN27_RS24545	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AYN27_RS24555	COG3789	protein conserved in bacteria
AYN27_RS24560	COG1842	Phage shock protein A
AYN27_RS24570	COG3766	membrane
AYN27_RS24575	COG5463	Belongs to the UPF0441 family
AYN27_RS24580	COG0754	glutathionylspermidine amidase activity
AYN27_RS24585	COG1960	acyl-CoA dehydrogenase activity
AYN27_RS24595	COG3650	response to hydrogen peroxide
AYN27_RS24600	COG1073	alpha beta
AYN27_RS24615	COG3037	sugar-specific permease SgaT UlaA
AYN27_RS24660	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AYN27_RS24755	COG2388	GCN5-related N-acetyl-transferase
AYN27_RS24760	COG3592	Divergent 4Fe-4S mono-cluster
AYN27_RS24765	COG3290	protein histidine kinase activity
AYN27_RS24770	COG4565	transcriptional regulatory protein
AYN27_RS24780	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AYN27_RS24785	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AYN27_RS24785	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AYN27_RS24790	COG3647	Membrane
AYN27_RS24800	COG2211	Major facilitator Superfamily
AYN27_RS24805	COG1486	melibiose metabolic process
AYN27_RS24815	COG2169	Transcriptional regulator
AYN27_RS24820	COG1982	Orn Lys Arg decarboxylase major
AYN27_RS24825	COG2207	Transcriptional regulator
AYN27_RS24830	COG0531	amino acid
AYN27_RS24835	COG2194	sulfuric ester hydrolase activity
AYN27_RS24840	COG0745	RESPONSE REGULATOR receiver
AYN27_RS24845	COG0642	Histidine kinase
AYN27_RS24855	COG0477	Major facilitator Superfamily
AYN27_RS24865	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AYN27_RS24875	COG2824	Alkylphosphonate utilization operon protein PhnA
AYN27_RS24880	COG2764	glyoxalase bleomycin resistance protein dioxygenase
AYN27_RS24890	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AYN27_RS24895	COG3639	organic phosphonate transmembrane transporter activity
AYN27_RS24900	COG2188	Transcriptional regulator
AYN27_RS24905	COG3624	Phosphonate C-P lyase system protein PhnG
AYN27_RS24910	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AYN27_RS24915	COG3626	phosphonate metabolism
AYN27_RS24920	COG3627	carbon phosphorus lyase activity
AYN27_RS24925	COG4107	phosphonate C-P lyase system protein PhnK
AYN27_RS24930	COG4778	phosphonate C-P lyase system protein PhnL
AYN27_RS24935	COG3454	Phosphonate metabolism
AYN27_RS24940	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AYN27_RS24945	COG0456	acetyltransferase
AYN27_RS24950	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AYN27_RS24960	COG0698	ribose 5-phosphate isomerase
AYN27_RS24965	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AYN27_RS24975	COG1566	PFAM secretion protein HlyD family protein
AYN27_RS24980	COG1289	transmembrane transporter activity
AYN27_RS24995	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AYN27_RS25000	COG1301	dicarboxylic acid transport
AYN27_RS25010	COG4235	cytochrome complex assembly
AYN27_RS25015	COG3088	subunit of a heme lyase
AYN27_RS25020	COG1138	Cytochrome C-type biogenesis protein
AYN27_RS25025	COG3301	Polysulphide reductase, NrfD
AYN27_RS25030	COG0437	4 iron, 4 sulfur cluster binding
AYN27_RS25035	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
AYN27_RS25055	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AYN27_RS25060	COG3162	membrane
AYN27_RS25075	COG0025	NhaP-type Na H and K H
AYN27_RS25080	COG2252	PERMEase
AYN27_RS25100	COG0789	Transcriptional regulator
AYN27_RS25105	COG2207	Transcriptional regulator
AYN27_RS25110	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AYN27_RS25125	COG0629	single-stranded DNA binding
AYN27_RS25130	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AYN27_RS25135	COG2315	Protein conserved in bacteria
AYN27_RS25140	COG0432	Pfam Uncharacterised protein family UPF0047
AYN27_RS25145	COG3700	Belongs to the class B bacterial acid phosphatase family
AYN27_RS25155	COG1448	Aminotransferase
AYN27_RS25160	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AYN27_RS25165	COG0305	Participates in initiation and elongation during chromosome replication
AYN27_RS25170	COG0604	alcohol dehydrogenase
AYN27_RS25180	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AYN27_RS25200	COG0727	PFAM Uncharacterised protein family (UPF0153)
AYN27_RS25230	COG5301	cellulose 1,4-beta-cellobiosidase activity
AYN27_RS25360	COG3772	lysozyme
AYN27_RS25405	COG0484	heat shock protein binding
AYN27_RS25450	COG5532	Uncharacterized conserved protein (DUF2303)
AYN27_RS25455	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AYN27_RS25500	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AYN27_RS25515	COG0735	belongs to the Fur family
AYN27_RS25520	COG3237	CsbD-like
AYN27_RS25525	COG0534	Mate efflux family protein
AYN27_RS25535	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AYN27_RS25560	COG1357	PFAM Pentapeptide repeats (8 copies)
AYN27_RS25580	COG3842	ATPase activity
AYN27_RS25590	COG2182	Extracellular solute-binding protein
AYN27_RS25595	COG1175	transmembrane transport
AYN27_RS25600	COG3833	ABC-type maltose transport systems, permease component
AYN27_RS25605	COG0477	Major facilitator Superfamily
AYN27_RS25605	COG2814	Major facilitator Superfamily
AYN27_RS25620	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AYN27_RS25650	COG0527	aspartate kinase activity
AYN27_RS25655	COG0542	response to heat
AYN27_RS25660	COG3541	Predicted nucleotidyltransferase
AYN27_RS25720	COG1283	sodium-dependent phosphate transmembrane transporter activity
AYN27_RS25725	COG0646	methionine synthase
AYN27_RS25725	COG1410	methionine synthase
AYN27_RS25730	COG1414	Transcriptional regulator
AYN27_RS25745	COG2224	Isocitrate lyase
AYN27_RS25750	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AYN27_RS25760	COG0456	acetyltransferase
AYN27_RS25795	COG0151	Belongs to the GarS family
AYN27_RS25800	COG2204	response regulator
AYN27_RS25805	COG4191	Histidine kinase
AYN27_RS25815	COG3678	ATP-independent chaperone mediated protein folding
AYN27_RS25830	COG3068	Protein conserved in bacteria
AYN27_RS25865	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AYN27_RS25870	COG2104	thiamine diphosphate biosynthetic process
AYN27_RS25880	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AYN27_RS25925	COG0250	Participates in transcription elongation, termination and antitermination
AYN27_RS25930	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AYN27_RS25975	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AYN27_RS25975	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AYN27_RS26040	COG0583	DNA-binding transcription factor activity
AYN27_RS26055	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AYN27_RS26070	COG2194	sulfuric ester hydrolase activity
AYN27_RS26075	COG2207	Transcriptional regulator
AYN27_RS26080	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AYN27_RS26085	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AYN27_RS26090	COG1882	Formate acetyltransferase
AYN27_RS26095	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AYN27_RS26100	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AYN27_RS26105	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AYN27_RS26105	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN27_RS26105	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN27_RS26110	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AYN27_RS26115	COG0371	Dehydrogenase
AYN27_RS26120	COG3738	Protein conserved in bacteria
AYN27_RS26125	COG0697	spore germination
AYN27_RS26135	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AYN27_RS26140	COG0527	aspartate kinase activity
AYN27_RS26140	COG0460	homoserine dehydrogenase
AYN27_RS26145	COG0626	cystathionine gamma-synthase activity
AYN27_RS26155	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
AYN27_RS26175	COG3209	COG3209 Rhs family protein
AYN27_RS26185	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AYN27_RS26190	COG1609	Transcriptional regulator
AYN27_RS26195	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AYN27_RS26210	COG1575	Belongs to the MenA family. Type 1 subfamily
AYN27_RS26225	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AYN27_RS26235	COG1494	fructose-1,6-bisphosphatase
AYN27_RS26245	COG0589	response to stress
AYN27_RS26250	COG3691	Protein conserved in bacteria
AYN27_RS26255	COG3152	Membrane
AYN27_RS26275	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AYN27_RS26290	COG3678	ATP-independent chaperone mediated protein folding
AYN27_RS26295	COG0745	RESPONSE REGULATOR receiver
AYN27_RS26300	COG2205	protein histidine kinase activity
AYN27_RS26305	COG2258	MOSC domain
AYN27_RS26320	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AYN27_RS26355	COG1454	alcohol dehydrogenase
AYN27_RS26365	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN27_RS26370	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AYN27_RS26370	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AYN27_RS26375	COG1363	Peptidase, m42
AYN27_RS26380	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN27_RS26380	COG3711	transcriptional antiterminator
AYN27_RS26400	COG3383	formate dehydrogenase (NAD+) activity
AYN27_RS26400	COG0243	molybdopterin cofactor binding
AYN27_RS26405	COG3383	formate dehydrogenase (NAD+) activity
AYN27_RS26405	COG0243	molybdopterin cofactor binding
AYN27_RS26410	COG0437	4 iron, 4 sulfur cluster binding
AYN27_RS26415	COG2864	formate dehydrogenase
AYN27_RS26425	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AYN27_RS26430	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AYN27_RS26445	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
AYN27_RS26455	COG0456	acetyltransferase
AYN27_RS26470	COG1011	Hydrolase
AYN27_RS26475	COG1349	DNA-binding transcription factor activity
AYN27_RS26480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AYN27_RS26485	COG2084	Dehydrogenase
AYN27_RS26490	COG3684	Belongs to the aldolase LacD family
AYN27_RS26495	COG2942	2-epimerase
AYN27_RS26500	COG2017	converts alpha-aldose to the beta-anomer
AYN27_RS26505	COG1501	Belongs to the glycosyl hydrolase 31 family
AYN27_RS26510	COG2211	Major facilitator Superfamily
AYN27_RS26515	COG2211	Major facilitator Superfamily
AYN27_RS26520	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AYN27_RS26525	COG2271	Major facilitator Superfamily
AYN27_RS26530	COG1082	Xylose isomerase domain protein TIM barrel
AYN27_RS26535	COG2188	Transcriptional regulator
AYN27_RS26540	COG1217	gtp-binding protein TYPA
AYN27_RS26550	COG0174	glutamine synthetase
AYN27_RS26560	COG3852	Histidine kinase
AYN27_RS26565	COG2204	response regulator
AYN27_RS26575	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AYN27_RS26590	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AYN27_RS26590	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AYN27_RS26600	COG0204	Acyl-transferase
AYN27_RS26610	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AYN27_RS26615	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AYN27_RS26620	COG3084	Protein conserved in bacteria
AYN27_RS26625	COG0746	molybdenum cofactor guanylyltransferase activity
AYN27_RS26630	COG1763	Mo-molybdopterin cofactor biosynthetic process
AYN27_RS26660	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
AYN27_RS26665	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AYN27_RS26670	COG1739	Uncharacterized protein family UPF0029
AYN27_RS26690	COG0543	2 iron, 2 sulfur cluster binding
AYN27_RS26695	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AYN27_RS26700	COG0250	Participates in transcription elongation, termination and antitermination
AYN27_RS26710	COG0805	protein transport
AYN27_RS26715	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AYN27_RS26720	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AYN27_RS26730	COG3165	ubiquinone biosynthetic process from chorismate
AYN27_RS26740	COG1322	Protein conserved in bacteria
AYN27_RS26745	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
AYN27_RS26750	COG0412	Dienelactone hydrolase
AYN27_RS26760	COG0583	DNA-binding transcription factor activity
AYN27_RS26765	COG0697	spore germination
AYN27_RS26770	COG0561	phosphatase activity
AYN27_RS26775	COG2267	carboxylic ester hydrolase activity
AYN27_RS26780	COG1280	lysine exporter protein (LysE YggA)
AYN27_RS26785	COG1280	lysine exporter protein (LysE YggA)
AYN27_RS26790	COG0514	ATP-dependent DNA helicase (RecQ)
AYN27_RS26795	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
AYN27_RS26800	COG2050	protein possibly involved in aromatic compounds catabolism
AYN27_RS26835	COG0598	Magnesium transport protein CorA
AYN27_RS26840	COG3698	Phosphodiester glycosidase
AYN27_RS26845	COG0210	DNA helicase
AYN27_RS26850	COG1011	Hydrolase
AYN27_RS26860	COG3159	Protein conserved in bacteria
AYN27_RS26870	COG5567	small periplasmic lipoprotein
AYN27_RS26895	COG3072	Adenylate cyclase
AYN27_RS26910	COG1587	Uroporphyrinogen-III synthase
AYN27_RS26915	COG2959	enzyme of heme biosynthesis
AYN27_RS26920	COG3071	HemY protein
AYN27_RS26925	COG0641	radical SAM
AYN27_RS26950	COG1113	amino acid transport
AYN27_RS26970	COG2244	polysaccharide biosynthetic process
AYN27_RS26975	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AYN27_RS26980	COG0456	acetyltransferase
AYN27_RS26985	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AYN27_RS26990	COG1088	dTDP-glucose 4,6-dehydratase activity
AYN27_RS26995	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AYN27_RS27000	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AYN27_RS27005	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
AYN27_RS27010	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AYN27_RS27020	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AYN27_RS27030	COG3118	belongs to the thioredoxin family
AYN27_RS27050	COG0210	DNA helicase
AYN27_RS27055	COG3692	DNA binding
AYN27_RS27060	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AYN27_RS27070	COG0583	DNA-binding transcription factor activity
AYN27_RS27075	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AYN27_RS27085	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AYN27_RS27090	COG3978	acetolactate synthase activity
AYN27_RS27115	COG0606	chelatase, subunit chli
AYN27_RS27120	COG3085	chromosome segregation
AYN27_RS27160	COG2186	Transcriptional regulator
AYN27_RS27165	COG0477	Major facilitator Superfamily
AYN27_RS27170	COG1609	Transcriptional regulator
AYN27_RS27175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AYN27_RS27180	COG1879	ABC-type sugar transport system periplasmic component
AYN27_RS27185	COG1172	Belongs to the binding-protein-dependent transport system permease family
AYN27_RS27190	COG1129	ABC transporter
AYN27_RS27220	COG1522	sequence-specific DNA binding
AYN27_RS27225	COG0716	FMN binding
AYN27_RS27240	COG3312	ion transport
AYN27_RS27305	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AYN27_RS27320	COG3188	usher protein
AYN27_RS27330	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AYN27_RS27335	COG0573	inorganic phosphate transmembrane transporter activity
AYN27_RS27340	COG0581	inorganic phosphate transmembrane transporter activity
AYN27_RS27345	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AYN27_RS27350	COG0704	Plays a role in the regulation of phosphate uptake
AYN27_RS27355	COG3711	transcriptional antiterminator
AYN27_RS27365	COG2723	6-phospho-beta-galactosidase activity
AYN27_RS27375	COG2382	esterase
AYN27_RS27380	COG0363	glucosamine-6-phosphate deaminase activity
AYN27_RS27385	COG3196	Protein conserved in bacteria
AYN27_RS27395	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AYN27_RS27400	COG2252	PERMEase
AYN27_RS27405	COG0431	NADPH-dependent FMN reductase
AYN27_RS27410	COG2091	lysine biosynthetic process via aminoadipic acid
AYN27_RS27425	COG0814	amino acid
AYN27_RS27475	COG0592	DNA-directed DNA polymerase activity
AYN27_RS27485	COG0187	DNA topoisomerase II activity
AYN27_RS27490	COG3753	Protein conserved in bacteria
AYN27_RS27495	COG0561	phosphatase activity
AYN27_RS27505	COG2186	Transcriptional regulator
AYN27_RS27510	COG3734	2-keto-3-deoxy-galactonokinase
AYN27_RS27515	COG0800	Aldolase
AYN27_RS27525	COG2271	Major facilitator Superfamily
AYN27_RS27535	COG0823	Involved in the tonB-independent uptake of proteins
AYN27_RS27540	COG5645	(Lipo)protein
AYN27_RS27560	COG2188	Transcriptional regulator
AYN27_RS27575	COG2207	Transcriptional regulator
AYN27_RS27580	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AYN27_RS27585	COG3119	arylsulfatase activity
AYN27_RS27595	COG2149	membrane
AYN27_RS27605	COG0641	radical SAM
AYN27_RS27610	COG2814	Major facilitator Superfamily
AYN27_RS27645	COG0028	Belongs to the TPP enzyme family
AYN27_RS27650	COG0440	acetolactate synthase activity
AYN27_RS27655	COG2197	response regulator
AYN27_RS27660	COG3851	Histidine kinase
AYN27_RS27665	COG2271	Major facilitator Superfamily
AYN27_RS27670	COG2271	Major facilitator Superfamily
AYN27_RS27680	COG2252	PERMEase
AYN27_RS27710	COG1464	Belongs to the NlpA lipoprotein family
AYN27_RS27715	COG0697	spore germination
AYN27_RS27720	COG2814	Major facilitator Superfamily
AYN27_RS27735	COG2211	Major facilitator Superfamily
AYN27_RS27740	COG1501	Belongs to the glycosyl hydrolase 31 family
AYN27_RS27745	COG2982	Protein involved in outer membrane biogenesis
AYN27_RS27750	COG2233	PERMEase
AYN27_RS27755	COG0786	glutamate:sodium symporter activity
AYN27_RS27765	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AYN27_RS27770	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AYN27_RS27775	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AYN27_RS27785	COG0194	GDP metabolic process
AYN27_RS27795	COG2860	membrane
AYN27_RS27800	COG3645	SOS response
AYN27_RS27805	COG1561	YicC-like family, N-terminal region
AYN27_RS27835	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AYN27_RS27865	COG1519	Transferase
AYN27_RS27870	COG0859	PFAM glycosyl transferase family 9
AYN27_RS27875	COG0438	transferase activity, transferring glycosyl groups
AYN27_RS27880	COG0515	serine threonine protein kinase
AYN27_RS27890	COG3642	lipopolysaccharide core region biosynthetic process
AYN27_RS27910	COG0859	PFAM glycosyl transferase family 9
AYN27_RS27915	COG0859	PFAM glycosyl transferase family 9
AYN27_RS27930	COG0156	8-amino-7-oxononanoate synthase activity
AYN27_RS27940	COG1216	Glycosyl transferase, family 2
AYN27_RS27945	COG2861	carbohydrate metabolic process
AYN27_RS27950	COG4942	peptidase
AYN27_RS27965	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AYN27_RS27970	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AYN27_RS27985	COG1045	serine acetyltransferase
AYN27_RS27990	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AYN27_RS28000	COG2186	Transcriptional regulator
AYN27_RS28005	COG1620	l-lactate permease
AYN27_RS28015	COG5295	Hep Hag repeat protein
AYN27_RS28040	COG3722	fumarate hydratase activity
AYN27_RS28050	COG2213	PTS system mannitol-specific
AYN27_RS28050	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYN27_RS28060	COG1566	PFAM secretion protein HlyD family protein
AYN27_RS28080	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AYN27_RS28090	COG1413	lyase activity
AYN27_RS28095	COG3209	COG3209 Rhs family protein
AYN27_RS28110	COG0625	glutathione transferase activity
AYN27_RS28120	COG3276	selenocysteine insertion sequence binding
AYN27_RS28125	COG1454	alcohol dehydrogenase
AYN27_RS28130	COG1012	belongs to the aldehyde dehydrogenase family
AYN27_RS28145	COG1566	PFAM secretion protein HlyD family protein
AYN27_RS28150	COG0583	DNA-binding transcription factor activity
AYN27_RS28155	COG3713	MltA-interacting MipA family protein
AYN27_RS28165	COG0235	Class ii aldolase
AYN27_RS28170	COG3623	hexulose-6-phosphate isomerase
AYN27_RS28175	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AYN27_RS28180	COG1070	Carbohydrate kinase
AYN27_RS28185	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AYN27_RS28190	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AYN27_RS28195	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AYN27_RS28200	COG2731	YhcH YjgK YiaL family protein
AYN27_RS28210	COG1414	Transcriptional regulator
AYN27_RS28215	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AYN27_RS28220	COG3977	Valine--pyruvate aminotransferase
AYN27_RS28225	COG0366	Alpha amylase catalytic
AYN27_RS28230	COG2992	FlgJ-related protein
AYN27_RS28235	COG2207	Transcriptional regulator
AYN27_RS28235	COG1609	Transcriptional regulator
AYN27_RS28240	COG4214	carbohydrate transport
AYN27_RS28245	COG1129	ABC transporter
AYN27_RS28250	COG4213	ABC transporter substrate-binding protein
AYN27_RS28260	COG1070	Carbohydrate kinase
AYN27_RS28265	COG4682	membrane
AYN27_RS28270	COG4682	membrane
AYN27_RS28275	COG3274	enterobacterial common antigen metabolic process
AYN27_RS28300	COG1278	Cold shock
AYN27_RS28305	COG2944	sequence-specific DNA binding
AYN27_RS28320	COG2885	chlorophyll binding
AYN27_RS28325	COG0243	molybdopterin cofactor binding
AYN27_RS28330	COG0456	acetyltransferase
AYN27_RS28335	COG2818	Glycosylase
AYN27_RS28340	COG5571	outer membrane autotransporter
AYN27_RS28350	COG2223	nitrite transmembrane transporter activity
AYN27_RS28380	COG2194	sulfuric ester hydrolase activity
AYN27_RS28400	COG0747	negative chemotaxis
AYN27_RS28410	COG0601	transmembrane transport
AYN27_RS28415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AYN27_RS28420	COG0444	Belongs to the ABC transporter superfamily
AYN27_RS28425	COG4608	Belongs to the ABC transporter superfamily
AYN27_RS28430	COG0814	amino acid
AYN27_RS28460	COG2194	sulfuric ester hydrolase activity
AYN27_RS28485	COG1215	transferase activity, transferring glycosyl groups
AYN27_RS28495	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AYN27_RS28500	COG0457	Tetratricopeptide repeat
AYN27_RS28500	COG3118	belongs to the thioredoxin family
AYN27_RS28505	COG2199	diguanylate cyclase activity
AYN27_RS28505	COG2200	EAL domain
AYN27_RS28520	COG0612	Peptidase, M16
AYN27_RS28535	COG2200	EAL domain
AYN27_RS28540	COG2982	Protein involved in outer membrane biogenesis
AYN27_RS28545	COG0477	Major facilitator Superfamily
AYN27_RS28550	COG1295	ribonuclease BN
AYN27_RS28555	COG0583	DNA-binding transcription factor activity
AYN27_RS28560	COG2197	response regulator
AYN27_RS28570	COG1858	cytochrome C peroxidase
AYN27_RS28575	COG0076	glutamate decarboxylase activity
AYN27_RS28585	COG2207	Transcriptional regulator
AYN27_RS28595	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AYN27_RS28600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYN27_RS28610	COG2771	luxR family
AYN27_RS28615	COG3247	response to pH
AYN27_RS28630	COG1285	pathogenesis
AYN27_RS28645	COG3065	identical protein binding
AYN27_RS28675	COG1393	Belongs to the ArsC family
AYN27_RS28680	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AYN27_RS28685	COG0640	Transcriptional regulator
AYN27_RS28700	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AYN27_RS28705	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AYN27_RS28710	COG0339	signal peptide processing
AYN27_RS28720	COG3104	oligopeptide transport
AYN27_RS28730	COG0589	response to stress
AYN27_RS28740	COG0306	phosphate transporter
AYN27_RS28745	COG2081	HI0933 family
AYN27_RS28770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYN27_RS28775	COG1129	ABC transporter
AYN27_RS28775	COG0842	Transport permease protein
AYN27_RS28780	COG0842	Transport permease protein
AYN27_RS28790	COG1413	lyase activity
AYN27_RS28800	COG3209	COG3209 Rhs family protein
AYN27_RS28815	COG0444	Belongs to the ABC transporter superfamily
AYN27_RS28820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AYN27_RS28825	COG0601	transmembrane transport
AYN27_RS28830	COG0747	negative chemotaxis
AYN27_RS28835	COG2091	lysine biosynthetic process via aminoadipic acid
AYN27_RS28840	COG0628	permease
AYN27_RS28855	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AYN27_RS28870	COG3714	YhhN family
AYN27_RS28880	COG3776	membrane
AYN27_RS28885	COG0742	ribosomal rna small subunit methyltransferase
AYN27_RS28890	COG0552	protein localization to endoplasmic reticulum
AYN27_RS28895	COG2884	Cell division ATP-binding protein ftsE
AYN27_RS28900	COG2177	Part of the ABC transporter FtsEX involved in
AYN27_RS28905	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AYN27_RS28910	COG0683	leucine binding
AYN27_RS28915	COG0456	acetyltransferase
AYN27_RS28920	COG0683	leucine binding
AYN27_RS28925	COG0559	Belongs to the binding-protein-dependent transport system permease family
AYN27_RS28930	COG4177	L-phenylalanine transmembrane transporter activity
AYN27_RS28935	COG0411	ABC transporter
AYN27_RS28960	COG3436	PFAM IS66 Orf2 family protein
AYN27_RS28965	COG4372	Transposase
AYN27_RS29020	COG3436	PFAM IS66 Orf2 family protein
AYN27_RS29025	COG4372	Transposase
AYN27_RS29100	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AYN27_RS29240	COG1192	Involved in chromosome partitioning
AYN27_RS29260	COG0697	spore germination
AYN27_RS29330	COG3300	MHYT domain
AYN27_RS29330	COG5001	Diguanylate cyclase
AYN27_RS29520	COG1585	Membrane protein implicated in regulation of membrane protease activity
AYN27_RS29525	COG2268	Band 7 protein
AYN27_RS29565	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AYN27_RS29580	COG0741	lytic transglycosylase activity
AYN27_RS29640	COG2805	Type II/IV secretion system protein
AYN27_RS29940	COG3436	PFAM IS66 Orf2 family protein
AYN27_RS29975	COG1475	DNA binding
AYN27_RS30155	COG5001	Diguanylate cyclase
AYN27_RS30155	COG3300	MHYT domain
AYN27_RS30180	COG3173	Aminoglycoside phosphotransferase
AYN27_RS30260	COG1660	Displays ATPase and GTPase activities
AYN27_RS30400	COG4372	Transposase
AYN27_RS30410	COG1560	Kdo2-lipid A biosynthetic process
AYN27_RS30415	COG2194	sulfuric ester hydrolase activity
AYN27_RS30420	COG0297	glycogen (starch) synthase activity
AYN27_RS30425	COG0726	polysaccharide deacetylase
AYN27_RS30470	COG2274	protein secretion by the type I secretion system
AYN27_RS30485	COG4372	Transposase