locus-tag	class	description
C6997_RS00020	COG0070	glutamate synthase
C6997_RS00020	COG0069	glutamate synthase activity
C6997_RS00020	COG0067	glutamate synthase
C6997_RS00025	COG0493	'glutamate synthase
C6997_RS00035	COG2731	YhcH YjgK YiaL family protein
C6997_RS00070	COG3069	C4-dicarboxylate transmembrane transporter activity
C6997_RS00075	COG2969	positive regulation of protein catabolic process
C6997_RS00080	COG0625	glutathione transferase activity
C6997_RS00110	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
C6997_RS00115	COG3105	Protein conserved in bacteria
C6997_RS00120	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C6997_RS00125	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C6997_RS00145	COG2732	(Barnase) inhibitor
C6997_RS00165	COG0583	DNA-binding transcription factor activity
C6997_RS00170	COG0312	modulator of DNA gyrase
C6997_RS00175	COG3164	Protein of unknown function
C6997_RS00180	COG1530	ribonuclease E activity
C6997_RS00190	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C6997_RS00195	COG1792	Involved in formation and maintenance of cell shape
C6997_RS00200	COG1077	Cell shape determining protein MreB Mrl
C6997_RS00215	COG2200	EAL domain
C6997_RS00215	COG2199	diguanylate cyclase activity
C6997_RS00220	COG0604	alcohol dehydrogenase
C6997_RS00235	COG0511	ligase activity, forming carbon-carbon bonds
C6997_RS00240	COG0439	Biotin carboxylase
C6997_RS00250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6997_RS00255	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6997_RS00260	COG1129	ABC transporter
C6997_RS00265	COG1879	ABC-type sugar transport system periplasmic component
C6997_RS00275	COG1349	DNA-binding transcription factor activity
C6997_RS00280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6997_RS00285	COG3924	membrane
C6997_RS00290	COG4145	pantothenate transmembrane transporter activity
C6997_RS00300	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C6997_RS00310	COG2189	Belongs to the N(4) N(6)-methyltransferase family
C6997_RS00320	COG1309	transcriptional regulator
C6997_RS00330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6997_RS00335	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C6997_RS00350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6997_RS00370	COG0765	amino acid transport
C6997_RS00375	COG1126	abc transporter atp-binding protein
C6997_RS00420	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C6997_RS00440	COG0551	DNA topoisomerase type I activity
C6997_RS00450	COG0758	DNA mediated transformation
C6997_RS00470	COG0569	domain protein
C6997_RS00480	COG3036	rescue of stalled ribosome
C6997_RS00485	COG0789	Transcriptional regulator
C6997_RS00525	COG0201	protein transport
C6997_RS00615	COG0089	rRNA binding
C6997_RS00695	COG2964	Protein conserved in bacteria
C6997_RS00700	COG0545	Peptidyl-prolyl cis-trans isomerase
C6997_RS00710	COG1047	Peptidyl-prolyl cis-trans
C6997_RS00715	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
C6997_RS00735	COG0488	(ABC) transporter
C6997_RS00740	COG0429	hydrolase of the alpha beta-hydrolase fold
C6997_RS00750	COG3954	Phosphoribulokinase
C6997_RS00755	COG1765	OsmC-like protein
C6997_RS00765	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C6997_RS00770	COG1289	transmembrane transporter activity
C6997_RS00775	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C6997_RS00780	COG0512	Glutamine amidotransferase of anthranilate synthase
C6997_RS00785	COG2184	nucleotidyltransferase activity
C6997_RS00795	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C6997_RS00805	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C6997_RS00810	COG2146	nitrite reductase [NAD(P)H] activity
C6997_RS00815	COG2116	formate transmembrane transporter activity
C6997_RS00830	COG0531	amino acid
C6997_RS00835	COG2222	sugar isomerase
C6997_RS00845	COG1082	Xylose isomerase domain protein TIM barrel
C6997_RS00855	COG2188	Transcriptional regulator
C6997_RS00860	COG0626	cystathionine gamma-synthase activity
C6997_RS00875	COG1735	metal-dependent hydrolase with the TIM-barrel fold
C6997_RS00880	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
C6997_RS00885	COG3457	Alanine racemase
C6997_RS00895	COG2188	Transcriptional regulator
C6997_RS00900	COG0180	Tryptophanyl-tRNA synthetase
C6997_RS00905	COG0546	phosphoglycolate phosphatase activity
C6997_RS00910	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C6997_RS00915	COG0338	D12 class N6 adenine-specific DNA methyltransferase
C6997_RS00920	COG3266	domain, Protein
C6997_RS00940	COG4796	Type ii and iii secretion system protein
C6997_RS00955	COG3166	PFAM Fimbrial assembly family protein
C6997_RS00960	COG4972	Pilus assembly protein
C6997_RS00965	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
C6997_RS00970	COG0494	nUDIX hydrolase
C6997_RS00980	COG1011	Hydrolase
C6997_RS00985	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C6997_RS00995	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
C6997_RS01025	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C6997_RS01030	COG2183	response to ionizing radiation
C6997_RS01040	COG1918	ferrous iron import across plasma membrane
C6997_RS01045	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
C6997_RS01060	COG5464	transposase or invertase
C6997_RS01080	COG2610	gluconate transmembrane transporter activity
C6997_RS01085	COG1640	4-alpha-glucanotransferase
C6997_RS01090	COG0058	SHG alpha-glucan phosphorylase activity
C6997_RS01105	COG1690	Belongs to the RtcB family
C6997_RS01110	COG4650	regulator
C6997_RS01115	COG1349	DNA-binding transcription factor activity
C6997_RS01130	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C6997_RS01150	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C6997_RS01155	COG0058	SHG alpha-glucan phosphorylase activity
C6997_RS01180	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C6997_RS01185	COG2095	MarC family integral membrane protein
C6997_RS01190	COG2610	gluconate transmembrane transporter activity
C6997_RS01195	COG3265	gluconokinase activity
C6997_RS01200	COG1609	Transcriptional regulator
C6997_RS01205	COG1741	Belongs to the pirin family
C6997_RS01210	COG0673	inositol 2-dehydrogenase activity
C6997_RS01220	COG1247	-acetyltransferase
C6997_RS01225	COG3157	Type VI secretion system effector, Hcp
C6997_RS01245	COG0405	Gamma-glutamyltransferase
C6997_RS01255	COG0584	glycerophosphoryl diester phosphodiesterase
C6997_RS01260	COG3842	ATPase activity
C6997_RS01270	COG1175	transmembrane transport
C6997_RS01275	COG1653	transport
C6997_RS01280	COG0410	ABC transporter
C6997_RS01285	COG0411	ABC transporter
C6997_RS01290	COG4177	L-phenylalanine transmembrane transporter activity
C6997_RS01295	COG0559	Belongs to the binding-protein-dependent transport system permease family
C6997_RS01300	COG0683	leucine binding
C6997_RS01305	COG0456	acetyltransferase
C6997_RS01310	COG0683	leucine binding
C6997_RS01315	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C6997_RS01320	COG2177	Part of the ABC transporter FtsEX involved in
C6997_RS01325	COG2884	Cell division ATP-binding protein ftsE
C6997_RS01330	COG0552	protein localization to endoplasmic reticulum
C6997_RS01335	COG0742	ribosomal rna small subunit methyltransferase
C6997_RS01340	COG3776	membrane
C6997_RS01350	COG3714	YhhN family
C6997_RS01365	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C6997_RS01380	COG0628	permease
C6997_RS01385	COG2091	lysine biosynthetic process via aminoadipic acid
C6997_RS01390	COG0747	negative chemotaxis
C6997_RS01395	COG0601	transmembrane transport
C6997_RS01400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C6997_RS01405	COG0444	Belongs to the ABC transporter superfamily
C6997_RS01420	COG3209	COG3209 Rhs family protein
C6997_RS01430	COG1413	lyase activity
C6997_RS01440	COG0842	Transport permease protein
C6997_RS01445	COG1129	ABC transporter
C6997_RS01445	COG0842	Transport permease protein
C6997_RS01450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6997_RS01475	COG2081	HI0933 family
C6997_RS01480	COG0306	phosphate transporter
C6997_RS01490	COG0589	response to stress
C6997_RS01500	COG3104	oligopeptide transport
C6997_RS01510	COG0339	signal peptide processing
C6997_RS01515	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
C6997_RS01520	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C6997_RS01535	COG0640	Transcriptional regulator
C6997_RS01540	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C6997_RS01545	COG1393	Belongs to the ArsC family
C6997_RS01565	COG3065	identical protein binding
C6997_RS01580	COG1285	pathogenesis
C6997_RS01595	COG3247	response to pH
C6997_RS01600	COG2771	luxR family
C6997_RS01610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6997_RS01615	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C6997_RS01625	COG2207	Transcriptional regulator
C6997_RS01635	COG0076	glutamate decarboxylase activity
C6997_RS01640	COG1858	cytochrome C peroxidase
C6997_RS01650	COG2197	response regulator
C6997_RS01655	COG0583	DNA-binding transcription factor activity
C6997_RS01660	COG1295	ribonuclease BN
C6997_RS01665	COG0477	Major facilitator Superfamily
C6997_RS01670	COG2982	Protein involved in outer membrane biogenesis
C6997_RS01675	COG2200	EAL domain
C6997_RS01690	COG0612	Peptidase, M16
C6997_RS01710	COG2200	EAL domain
C6997_RS01710	COG2199	diguanylate cyclase activity
C6997_RS01715	COG0457	Tetratricopeptide repeat
C6997_RS01715	COG3118	belongs to the thioredoxin family
C6997_RS01720	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
C6997_RS01725	COG1215	transferase activity, transferring glycosyl groups
C6997_RS01730	COG1215	transferase activity, transferring glycosyl groups
C6997_RS01755	COG2194	sulfuric ester hydrolase activity
C6997_RS01800	COG0814	amino acid
C6997_RS01805	COG4608	Belongs to the ABC transporter superfamily
C6997_RS01810	COG0444	Belongs to the ABC transporter superfamily
C6997_RS01815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C6997_RS01820	COG0601	transmembrane transport
C6997_RS01830	COG0747	negative chemotaxis
C6997_RS01840	COG3547	Transposase (IS116 IS110 IS902 family)
C6997_RS01860	COG2194	sulfuric ester hydrolase activity
C6997_RS01890	COG2223	nitrite transmembrane transporter activity
C6997_RS01900	COG5571	outer membrane autotransporter
C6997_RS01905	COG2818	Glycosylase
C6997_RS01910	COG0456	acetyltransferase
C6997_RS01915	COG0243	molybdopterin cofactor binding
C6997_RS01920	COG2885	chlorophyll binding
C6997_RS01935	COG2944	sequence-specific DNA binding
C6997_RS01940	COG1278	Cold shock
C6997_RS01965	COG3274	enterobacterial common antigen metabolic process
C6997_RS01970	COG4682	membrane
C6997_RS01975	COG4682	membrane
C6997_RS01980	COG1070	Carbohydrate kinase
C6997_RS01990	COG4213	ABC transporter substrate-binding protein
C6997_RS01995	COG1129	ABC transporter
C6997_RS02000	COG4214	carbohydrate transport
C6997_RS02005	COG1609	Transcriptional regulator
C6997_RS02005	COG2207	Transcriptional regulator
C6997_RS02010	COG2992	FlgJ-related protein
C6997_RS02015	COG0366	Alpha amylase catalytic
C6997_RS02020	COG3977	Valine--pyruvate aminotransferase
C6997_RS02025	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6997_RS02030	COG1414	Transcriptional regulator
C6997_RS02040	COG2731	YhcH YjgK YiaL family protein
C6997_RS02045	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
C6997_RS02050	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
C6997_RS02055	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C6997_RS02060	COG1070	Carbohydrate kinase
C6997_RS02065	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
C6997_RS02070	COG3623	hexulose-6-phosphate isomerase
C6997_RS02075	COG0235	Class ii aldolase
C6997_RS02085	COG3713	MltA-interacting MipA family protein
C6997_RS02090	COG0583	DNA-binding transcription factor activity
C6997_RS02095	COG1566	PFAM secretion protein HlyD family protein
C6997_RS02110	COG1012	belongs to the aldehyde dehydrogenase family
C6997_RS02115	COG1454	alcohol dehydrogenase
C6997_RS02120	COG3276	selenocysteine insertion sequence binding
C6997_RS02130	COG0625	glutathione transferase activity
C6997_RS02135	COG3209	COG3209 Rhs family protein
C6997_RS02140	COG1413	lyase activity
C6997_RS02145	COG3209	COG3209 Rhs family protein
C6997_RS02150	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C6997_RS02180	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6997_RS02180	COG2213	PTS system mannitol-specific
C6997_RS02190	COG3722	fumarate hydratase activity
C6997_RS02215	COG5295	Hep Hag repeat protein
C6997_RS02225	COG1620	l-lactate permease
C6997_RS02230	COG2186	Transcriptional regulator
C6997_RS02240	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C6997_RS02245	COG1045	serine acetyltransferase
C6997_RS02260	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C6997_RS02265	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C6997_RS02280	COG4942	peptidase
C6997_RS02285	COG2861	carbohydrate metabolic process
C6997_RS02290	COG1216	Glycosyl transferase, family 2
C6997_RS02300	COG0156	8-amino-7-oxononanoate synthase activity
C6997_RS02315	COG0859	PFAM glycosyl transferase family 9
C6997_RS02320	COG0859	PFAM glycosyl transferase family 9
C6997_RS02340	COG3642	lipopolysaccharide core region biosynthetic process
C6997_RS02350	COG0515	serine threonine protein kinase
C6997_RS02355	COG0438	transferase activity, transferring glycosyl groups
C6997_RS02360	COG0859	PFAM glycosyl transferase family 9
C6997_RS02365	COG1519	Transferase
C6997_RS02395	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C6997_RS02425	COG1561	YicC-like family, N-terminal region
C6997_RS02430	COG3645	SOS response
C6997_RS02435	COG2860	membrane
C6997_RS02445	COG0194	GDP metabolic process
C6997_RS02455	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C6997_RS02460	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C6997_RS02465	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C6997_RS02475	COG0786	glutamate:sodium symporter activity
C6997_RS02480	COG2233	PERMEase
C6997_RS02485	COG2982	Protein involved in outer membrane biogenesis
C6997_RS02490	COG1501	Belongs to the glycosyl hydrolase 31 family
C6997_RS02495	COG2211	Major facilitator Superfamily
C6997_RS02505	COG0582	viral genome integration into host DNA
C6997_RS02560	COG4372	Transposase
C6997_RS02565	COG3436	PFAM IS66 Orf2 family protein
C6997_RS02605	COG2814	Major facilitator Superfamily
C6997_RS02610	COG0697	spore germination
C6997_RS02615	COG1464	Belongs to the NlpA lipoprotein family
C6997_RS02645	COG2252	PERMEase
C6997_RS02655	COG2271	Major facilitator Superfamily
C6997_RS02660	COG2271	Major facilitator Superfamily
C6997_RS02665	COG3851	Histidine kinase
C6997_RS02670	COG2197	response regulator
C6997_RS02675	COG0440	acetolactate synthase activity
C6997_RS02680	COG0028	Belongs to the TPP enzyme family
C6997_RS02715	COG2814	Major facilitator Superfamily
C6997_RS02720	COG0641	radical SAM
C6997_RS02730	COG2149	membrane
C6997_RS02740	COG3119	arylsulfatase activity
C6997_RS02745	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C6997_RS02750	COG2207	Transcriptional regulator
C6997_RS02765	COG2188	Transcriptional regulator
C6997_RS02785	COG5645	(Lipo)protein
C6997_RS02790	COG0823	Involved in the tonB-independent uptake of proteins
C6997_RS02800	COG2271	Major facilitator Superfamily
C6997_RS02810	COG0800	Aldolase
C6997_RS02815	COG3734	2-keto-3-deoxy-galactonokinase
C6997_RS02820	COG2186	Transcriptional regulator
C6997_RS02830	COG0561	phosphatase activity
C6997_RS02835	COG3753	Protein conserved in bacteria
C6997_RS02840	COG3547	Transposase (IS116 IS110 IS902 family)
C6997_RS02850	COG0187	DNA topoisomerase II activity
C6997_RS02860	COG0592	DNA-directed DNA polymerase activity
C6997_RS02910	COG0814	amino acid
C6997_RS02925	COG2091	lysine biosynthetic process via aminoadipic acid
C6997_RS02930	COG0431	NADPH-dependent FMN reductase
C6997_RS02935	COG2252	PERMEase
C6997_RS02940	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C6997_RS02950	COG3196	Protein conserved in bacteria
C6997_RS02955	COG0363	glucosamine-6-phosphate deaminase activity
C6997_RS02960	COG2382	esterase
C6997_RS02970	COG2723	6-phospho-beta-galactosidase activity
C6997_RS02975	COG1263	PTS System
C6997_RS02975	COG2190	(PTS) system
C6997_RS02975	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6997_RS02980	COG3711	transcriptional antiterminator
C6997_RS02985	COG0704	Plays a role in the regulation of phosphate uptake
C6997_RS02990	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C6997_RS02995	COG0581	inorganic phosphate transmembrane transporter activity
C6997_RS03000	COG0573	inorganic phosphate transmembrane transporter activity
C6997_RS03005	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C6997_RS03015	COG3188	usher protein
C6997_RS03030	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C6997_RS03085	COG3312	ion transport
C6997_RS03100	COG0716	FMN binding
C6997_RS03105	COG1522	sequence-specific DNA binding
C6997_RS03135	COG1129	ABC transporter
C6997_RS03140	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6997_RS03145	COG1879	ABC-type sugar transport system periplasmic component
C6997_RS03150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6997_RS03155	COG1609	Transcriptional regulator
C6997_RS03160	COG0477	Major facilitator Superfamily
C6997_RS03165	COG2186	Transcriptional regulator
C6997_RS03205	COG3085	chromosome segregation
C6997_RS03210	COG0606	chelatase, subunit chli
C6997_RS03235	COG3978	acetolactate synthase activity
C6997_RS03240	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C6997_RS03250	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C6997_RS03255	COG0583	DNA-binding transcription factor activity
C6997_RS03265	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C6997_RS03270	COG3692	DNA binding
C6997_RS03275	COG0210	DNA helicase
C6997_RS03295	COG3118	belongs to the thioredoxin family
C6997_RS03305	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C6997_RS03315	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C6997_RS03320	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
C6997_RS03325	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C6997_RS03330	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
C6997_RS03335	COG1088	dTDP-glucose 4,6-dehydratase activity
C6997_RS03340	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C6997_RS03345	COG0456	acetyltransferase
C6997_RS03350	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C6997_RS03355	COG2244	polysaccharide biosynthetic process
C6997_RS03375	COG1113	amino acid transport
C6997_RS03400	COG0641	radical SAM
C6997_RS03405	COG3071	HemY protein
C6997_RS03410	COG2959	enzyme of heme biosynthesis
C6997_RS03415	COG1587	Uroporphyrinogen-III synthase
C6997_RS03430	COG3072	Adenylate cyclase
C6997_RS03455	COG5567	small periplasmic lipoprotein
C6997_RS03465	COG3159	Protein conserved in bacteria
C6997_RS03475	COG1011	Hydrolase
C6997_RS03480	COG0210	DNA helicase
C6997_RS03485	COG3698	Phosphodiester glycosidase
C6997_RS03490	COG0598	Magnesium transport protein CorA
C6997_RS03520	COG2962	Rard protein
C6997_RS03525	COG2050	protein possibly involved in aromatic compounds catabolism
C6997_RS03530	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
C6997_RS03535	COG0514	ATP-dependent DNA helicase (RecQ)
C6997_RS03540	COG1280	lysine exporter protein (LysE YggA)
C6997_RS03545	COG1280	lysine exporter protein (LysE YggA)
C6997_RS03550	COG2267	carboxylic ester hydrolase activity
C6997_RS03555	COG0561	phosphatase activity
C6997_RS03560	COG0697	spore germination
C6997_RS03565	COG0583	DNA-binding transcription factor activity
C6997_RS03575	COG0412	Dienelactone hydrolase
C6997_RS03580	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
C6997_RS03590	COG1322	Protein conserved in bacteria
C6997_RS03600	COG3165	ubiquinone biosynthetic process from chorismate
C6997_RS03610	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C6997_RS03615	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C6997_RS03620	COG0805	protein transport
C6997_RS03630	COG0250	Participates in transcription elongation, termination and antitermination
C6997_RS03635	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C6997_RS03640	COG0543	2 iron, 2 sulfur cluster binding
C6997_RS03660	COG1739	Uncharacterized protein family UPF0029
C6997_RS03665	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C6997_RS03670	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
C6997_RS03700	COG1763	Mo-molybdopterin cofactor biosynthetic process
C6997_RS03705	COG0746	molybdenum cofactor guanylyltransferase activity
C6997_RS03710	COG3084	Protein conserved in bacteria
C6997_RS03715	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C6997_RS03720	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C6997_RS03725	COG5339	Protein conserved in bacteria
C6997_RS03730	COG0204	Acyl-transferase
C6997_RS03740	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C6997_RS03740	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C6997_RS03755	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C6997_RS03765	COG2204	response regulator
C6997_RS03770	COG3852	Histidine kinase
C6997_RS03780	COG0174	glutamine synthetase
C6997_RS03790	COG1217	gtp-binding protein TYPA
C6997_RS03795	COG2188	Transcriptional regulator
C6997_RS03800	COG1082	Xylose isomerase domain protein TIM barrel
C6997_RS03805	COG2271	Major facilitator Superfamily
C6997_RS03810	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
C6997_RS03815	COG2211	Major facilitator Superfamily
C6997_RS03820	COG2211	Major facilitator Superfamily
C6997_RS03825	COG1501	Belongs to the glycosyl hydrolase 31 family
C6997_RS03830	COG2017	converts alpha-aldose to the beta-anomer
C6997_RS03835	COG2942	2-epimerase
C6997_RS03840	COG3684	Belongs to the aldolase LacD family
C6997_RS03845	COG2084	Dehydrogenase
C6997_RS03850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6997_RS03855	COG1349	DNA-binding transcription factor activity
C6997_RS03860	COG1011	Hydrolase
C6997_RS03875	COG0456	acetyltransferase
C6997_RS03885	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
C6997_RS03900	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C6997_RS03905	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C6997_RS03915	COG2864	formate dehydrogenase
C6997_RS03920	COG0437	4 iron, 4 sulfur cluster binding
C6997_RS03945	COG3711	transcriptional antiterminator
C6997_RS03945	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6997_RS03950	COG1363	Peptidase, m42
C6997_RS03955	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6997_RS03955	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6997_RS03960	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6997_RS03970	COG1454	alcohol dehydrogenase
C6997_RS04005	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C6997_RS04020	COG2258	MOSC domain
C6997_RS04025	COG2205	protein histidine kinase activity
C6997_RS04030	COG0745	RESPONSE REGULATOR receiver
C6997_RS04035	COG3678	ATP-independent chaperone mediated protein folding
C6997_RS04040	COG4974	Belongs to the 'phage' integrase family
C6997_RS04100	COG4695	Portal protein
C6997_RS04200	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C6997_RS04215	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C6997_RS04275	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C6997_RS04295	COG3152	Membrane
C6997_RS04300	COG3691	Protein conserved in bacteria
C6997_RS04305	COG0589	response to stress
C6997_RS04315	COG1494	fructose-1,6-bisphosphatase
C6997_RS04325	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C6997_RS04340	COG1575	Belongs to the MenA family. Type 1 subfamily
C6997_RS04355	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C6997_RS04360	COG1609	Transcriptional regulator
C6997_RS04365	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C6997_RS04375	COG3209	COG3209 Rhs family protein
C6997_RS04395	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
C6997_RS04405	COG0626	cystathionine gamma-synthase activity
C6997_RS04410	COG0460	homoserine dehydrogenase
C6997_RS04410	COG0527	aspartate kinase activity
C6997_RS04415	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C6997_RS04425	COG0697	spore germination
C6997_RS04430	COG3738	Protein conserved in bacteria
C6997_RS04435	COG3547	Transposase (IS116 IS110 IS902 family)
C6997_RS04445	COG0371	Dehydrogenase
C6997_RS04450	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C6997_RS04460	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6997_RS04465	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6997_RS04475	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C6997_RS04480	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6997_RS04485	COG2207	Transcriptional regulator
C6997_RS04490	COG2194	sulfuric ester hydrolase activity
C6997_RS04505	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C6997_RS04520	COG0583	DNA-binding transcription factor activity
C6997_RS04585	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
C6997_RS04585	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
C6997_RS04630	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C6997_RS04635	COG0250	Participates in transcription elongation, termination and antitermination
C6997_RS04680	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
C6997_RS04690	COG2104	thiamine diphosphate biosynthetic process
C6997_RS04695	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C6997_RS04730	COG3068	Protein conserved in bacteria
C6997_RS04745	COG3678	ATP-independent chaperone mediated protein folding
C6997_RS04755	COG4191	Histidine kinase
C6997_RS04760	COG2204	response regulator
C6997_RS04765	COG0151	Belongs to the GarS family
C6997_RS04800	COG0456	acetyltransferase
C6997_RS04810	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C6997_RS04815	COG2224	Isocitrate lyase
C6997_RS04830	COG1414	Transcriptional regulator
C6997_RS04835	COG0646	methionine synthase
C6997_RS04835	COG1410	methionine synthase
C6997_RS04840	COG1283	sodium-dependent phosphate transmembrane transporter activity
C6997_RS04900	COG3541	Predicted nucleotidyltransferase
C6997_RS04905	COG0542	response to heat
C6997_RS04910	COG0527	aspartate kinase activity
C6997_RS04945	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C6997_RS04960	COG0477	Major facilitator Superfamily
C6997_RS04960	COG2814	Major facilitator Superfamily
C6997_RS04965	COG3833	ABC-type maltose transport systems, permease component
C6997_RS04970	COG1175	transmembrane transport
C6997_RS04975	COG2182	Extracellular solute-binding protein
C6997_RS04985	COG3842	ATPase activity
C6997_RS05005	COG1357	PFAM Pentapeptide repeats (8 copies)
C6997_RS05030	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C6997_RS05040	COG0534	Mate efflux family protein
C6997_RS05045	COG3237	CsbD-like
C6997_RS05050	COG0735	belongs to the Fur family
C6997_RS05065	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C6997_RS05115	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
C6997_RS05120	COG5532	Uncharacterized conserved protein (DUF2303)
C6997_RS05145	COG3646	Phage regulatory protein
C6997_RS05155	COG1846	Transcriptional regulator
C6997_RS05165	COG4725	Belongs to the MT-A70-like family
C6997_RS05175	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C6997_RS05190	COG1403	HNH endonuclease
C6997_RS05195	COG0484	heat shock protein binding
C6997_RS05245	COG3772	lysozyme
C6997_RS05400	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6997_RS05450	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C6997_RS05460	COG0604	alcohol dehydrogenase
C6997_RS05465	COG0305	Participates in initiation and elongation during chromosome replication
C6997_RS05470	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C6997_RS05475	COG1448	Aminotransferase
C6997_RS05485	COG3700	Belongs to the class B bacterial acid phosphatase family
C6997_RS05490	COG0432	Pfam Uncharacterised protein family UPF0047
C6997_RS05495	COG2315	Protein conserved in bacteria
C6997_RS05500	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C6997_RS05510	COG0629	single-stranded DNA binding
C6997_RS05525	COG4943	cyclic-guanylate-specific phosphodiesterase activity
C6997_RS05530	COG2207	Transcriptional regulator
C6997_RS05535	COG0789	Transcriptional regulator
C6997_RS05555	COG2252	PERMEase
C6997_RS05560	COG0025	NhaP-type Na H and K H
C6997_RS05575	COG3162	membrane
C6997_RS05580	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C6997_RS05595	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
C6997_RS05600	COG0437	4 iron, 4 sulfur cluster binding
C6997_RS05605	COG3301	Polysulphide reductase, NrfD
C6997_RS05610	COG1138	Cytochrome C-type biogenesis protein
C6997_RS05615	COG3088	subunit of a heme lyase
C6997_RS05620	COG4235	cytochrome complex assembly
C6997_RS05630	COG1301	dicarboxylic acid transport
C6997_RS05635	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C6997_RS05650	COG1289	transmembrane transporter activity
C6997_RS05655	COG1566	PFAM secretion protein HlyD family protein
C6997_RS05665	COG2015	COG2015, Alkyl sulfatase and related hydrolases
C6997_RS05670	COG0698	ribose 5-phosphate isomerase
C6997_RS05680	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C6997_RS05685	COG0456	acetyltransferase
C6997_RS05690	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
C6997_RS05695	COG3454	Phosphonate metabolism
C6997_RS05700	COG4778	phosphonate C-P lyase system protein PhnL
C6997_RS05705	COG4107	phosphonate C-P lyase system protein PhnK
C6997_RS05710	COG3627	carbon phosphorus lyase activity
C6997_RS05715	COG3626	phosphonate metabolism
C6997_RS05720	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
C6997_RS05725	COG3624	Phosphonate C-P lyase system protein PhnG
C6997_RS05730	COG2188	Transcriptional regulator
C6997_RS05735	COG3639	organic phosphonate transmembrane transporter activity
C6997_RS05740	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
C6997_RS05750	COG2764	glyoxalase bleomycin resistance protein dioxygenase
C6997_RS05755	COG2824	Alkylphosphonate utilization operon protein PhnA
C6997_RS05765	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C6997_RS05775	COG0477	Major facilitator Superfamily
C6997_RS05785	COG0642	Histidine kinase
C6997_RS05790	COG0745	RESPONSE REGULATOR receiver
C6997_RS05795	COG2194	sulfuric ester hydrolase activity
C6997_RS05800	COG0531	amino acid
C6997_RS05805	COG2207	Transcriptional regulator
C6997_RS05810	COG1982	Orn Lys Arg decarboxylase major
C6997_RS05815	COG2169	Transcriptional regulator
C6997_RS05825	COG1486	melibiose metabolic process
C6997_RS05830	COG2211	Major facilitator Superfamily
C6997_RS05840	COG3647	Membrane
C6997_RS05845	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C6997_RS05845	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C6997_RS05850	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C6997_RS05860	COG4565	transcriptional regulatory protein
C6997_RS05865	COG3290	protein histidine kinase activity
C6997_RS05870	COG3592	Divergent 4Fe-4S mono-cluster
C6997_RS05875	COG2388	GCN5-related N-acetyl-transferase
C6997_RS05895	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C6997_RS05900	COG3104	oligopeptide transport
C6997_RS05905	COG1982	Orn Lys Arg decarboxylase major
C6997_RS05910	COG0531	amino acid
C6997_RS05920	COG3710	Transcriptional regulator
C6997_RS06205	COG4372	Transposase
C6997_RS06210	COG0582	viral genome integration into host DNA
C6997_RS06220	COG1309	transcriptional regulator
C6997_RS06235	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C6997_RS06240	COG1027	Aspartate ammonia-lyase
C6997_RS06245	COG3030	protein affecting phage T7 exclusion by the F plasmid
C6997_RS06250	COG0531	amino acid
C6997_RS06275	COG3547	Transposase (IS116 IS110 IS902 family)
C6997_RS06285	COG1509	lysine 2,3-aminomutase activity
C6997_RS06295	COG5510	response to toxic substance
C6997_RS06300	COG5510	response to toxic substance
C6997_RS06305	COG2076	Multidrug Resistance protein
C6997_RS06310	COG3040	lipid binding
C6997_RS06315	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C6997_RS06330	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C6997_RS06335	COG1053	succinate dehydrogenase
C6997_RS06345	COG0531	amino acid
C6997_RS06360	COG3264	Mechanosensitive ion channel
C6997_RS06360	COG1511	domain protein
C6997_RS06405	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C6997_RS06405	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C6997_RS06410	COG0802	atpase or kinase
C6997_RS06415	COG0860	N-Acetylmuramoyl-L-alanine amidase
C6997_RS06435	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C6997_RS06440	COG0330	HflC and HflK could
C6997_RS06445	COG0330	HflC and HflK could
C6997_RS06450	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
C6997_RS06465	COG0557	exoribonuclease II activity
C6997_RS06470	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C6997_RS06480	COG3789	protein conserved in bacteria
C6997_RS06485	COG1842	Phage shock protein A
C6997_RS06495	COG3766	membrane
C6997_RS06500	COG5463	Belongs to the UPF0441 family
C6997_RS06505	COG0754	glutathionylspermidine amidase activity
C6997_RS06510	COG1960	acyl-CoA dehydrogenase activity
C6997_RS06520	COG3650	response to hydrogen peroxide
C6997_RS06525	COG1073	alpha beta
C6997_RS06540	COG3037	sugar-specific permease SgaT UlaA
C6997_RS06585	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C6997_RS06610	COG0675	Transposase, IS605 OrfB family
C6997_RS06620	COG3061	Opacity-associated protein A
C6997_RS06630	COG0545	Peptidyl-prolyl cis-trans isomerase
C6997_RS06635	COG1113	amino acid transport
C6997_RS06655	COG0697	spore germination
C6997_RS06660	COG0702	epimerase
C6997_RS06665	COG1733	regulation of RNA biosynthetic process
C6997_RS06670	COG0737	Belongs to the 5'-nucleotidase family
C6997_RS06675	COG1218	3'(2'),5'-bisphosphate nucleotidase
C6997_RS06680	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
C6997_RS06690	COG1253	flavin adenine dinucleotide binding
C6997_RS06705	COG0729	surface antigen
C6997_RS06710	COG2911	Protein conserved in bacteria
C6997_RS06715	COG2105	PFAM AIG2 family protein
C6997_RS06720	COG2336	PFAM SpoVT AbrB
C6997_RS06725	COG2337	Toxic component of a toxin-antitoxin (TA) module
C6997_RS06730	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
C6997_RS06735	COG1879	ABC-type sugar transport system periplasmic component
C6997_RS06740	COG1129	ABC transporter
C6997_RS06745	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6997_RS06750	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6997_RS06760	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C6997_RS06770	COG0312	modulator of DNA gyrase
C6997_RS06780	COG4372	Transposase
C6997_RS06785	COG3436	PFAM IS66 Orf2 family protein
C6997_RS06805	COG0602	queuosine metabolic process
C6997_RS06810	COG1328	CTP reductase activity
C6997_RS06815	COG0366	Alpha amylase catalytic
C6997_RS06820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6997_RS06820	COG1263	PTS System
C6997_RS06825	COG1609	Transcriptional regulator
C6997_RS06835	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C6997_RS06840	COG3547	Transposase (IS116 IS110 IS902 family)
C6997_RS06850	COG0251	oxidation-reduction process
C6997_RS06875	COG0251	oxidation-reduction process
C6997_RS06880	COG1028	Short-chain dehydrogenase reductase Sdr
C6997_RS06885	COG1309	transcriptional regulator
C6997_RS06890	COG2731	YhcH YjgK YiaL family protein
C6997_RS06910	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
C6997_RS06915	COG0456	acetyltransferase
C6997_RS06920	COG4269	membrane
C6997_RS06925	COG4269	membrane
C6997_RS06935	COG2927	DNA polymerase III (CHI subunit)
C6997_RS06945	COG0795	lipopolysaccharide-transporting ATPase activity
C6997_RS06950	COG0795	lipopolysaccharide-transporting ATPase activity
C6997_RS06955	COG0433	COG0433 Predicted ATPase
C6997_RS06960	COG1064	alcohol dehydrogenase
C6997_RS06970	COG0582	viral genome integration into host DNA
C6997_RS06995	COG3436	PFAM IS66 Orf2 family protein
C6997_RS07000	COG4372	Transposase
C6997_RS07065	COG2085	NADP oxidoreductase coenzyme F420-dependent
C6997_RS07070	COG1120	ATPase activity
C6997_RS07075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6997_RS07080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6997_RS07085	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
C6997_RS07090	COG4772	TonB-dependent receptor
C6997_RS07095	COG3712	iron ion homeostasis
C6997_RS07100	COG1595	DNA-templated transcription, initiation
C6997_RS07150	COG4372	Transposase
C6997_RS07155	COG3436	PFAM IS66 Orf2 family protein
C6997_RS07185	COG4372	Transposase
C6997_RS07190	COG3436	PFAM IS66 Orf2 family protein
C6997_RS07230	COG3436	PFAM IS66 Orf2 family protein
C6997_RS07235	COG4372	Transposase
C6997_RS07255	COG4983	Phage plasmid primase, P4 family domain protein
C6997_RS07270	COG3468	outer membrane autotransporter barrel domain protein
C6997_RS07275	COG2020	methyltransferase activity
C6997_RS07305	COG2003	Belongs to the UPF0758 family
C6997_RS07365	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
C6997_RS07370	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
C6997_RS07390	COG0582	viral genome integration into host DNA
C6997_RS07395	COG4974	Belongs to the 'phage' integrase family
C6997_RS07410	COG3539	Fimbrial protein
C6997_RS07415	COG3121	Chaperone
C6997_RS07420	COG3188	usher protein
C6997_RS07425	COG3539	Fimbrial protein
C6997_RS07430	COG3539	Fimbrial protein
C6997_RS07435	COG3539	Fimbrial protein
C6997_RS07455	COG0246	Mannitol dehydrogenase
C6997_RS07465	COG2186	Transcriptional regulator
C6997_RS07490	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C6997_RS07495	COG0700	Nucleoside recognition
C6997_RS07500	COG3366	ferrous iron transmembrane transporter activity
C6997_RS07515	COG0477	Major facilitator Superfamily
C6997_RS07530	COG1924	4 iron, 4 sulfur cluster binding
C6997_RS07535	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
C6997_RS07540	COG2733	membrane
C6997_RS07545	COG2814	Major facilitator Superfamily
C6997_RS07555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C6997_RS07560	COG5457	Domain of unknown function (DUF1127)
C6997_RS07575	COG0732	type I restriction modification DNA specificity domain
C6997_RS07600	COG0523	cobalamin synthesis protein
C6997_RS07605	COG2879	small protein
C6997_RS07610	COG1966	Carbon starvation protein
C6997_RS07620	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C6997_RS07625	COG2368	4-hydroxyphenylacetate
C6997_RS07645	COG3971	2-oxopent-4-enoate hydratase activity
C6997_RS07655	COG3384	dioxygenase
C6997_RS07660	COG1012	belongs to the aldehyde dehydrogenase family
C6997_RS07665	COG0179	Fumarylacetoacetate (FAA) hydrolase
C6997_RS07670	COG1846	Transcriptional regulator
C6997_RS07675	COG0840	transmembrane signaling receptor activity
C6997_RS07680	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
C6997_RS07690	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C6997_RS07695	COG0025	NhaP-type Na H and K H
C6997_RS07700	COG1802	Transcriptional regulator
C6997_RS07705	COG1063	alcohol dehydrogenase
C6997_RS07720	COG1484	DNA-dependent DNA replication
C6997_RS07735	COG2966	Psort location CytoplasmicMembrane, score
C6997_RS07740	COG2197	response regulator
C6997_RS07745	COG2197	response regulator
C6997_RS07750	COG4114	ferric iron reductase
C6997_RS07780	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
C6997_RS07785	COG0456	acetyltransferase
C6997_RS07790	COG1011	Hydrolase
C6997_RS07800	COG2823	Periplasmic or secreted lipoprotein
C6997_RS07810	COG4667	esterase of the alpha-beta hydrolase superfamily
C6997_RS07815	COG0084	hydrolase, TatD family'
C6997_RS07820	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C6997_RS07825	COG1328	CTP reductase activity
C6997_RS07860	COG3726	membrane protein affecting hemolysin expression
C6997_RS07865	COG0560	Phosphoserine phosphatase
C6997_RS07870	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C6997_RS07875	COG1056	cytidyltransferase-related domain
C6997_RS07875	COG3172	ATPase kinase involved in NAD metabolism
C6997_RS07880	COG0488	(ABC) transporter
C6997_RS07890	COG0741	lytic transglycosylase activity
C6997_RS07910	COG3708	Transcriptional regulator
C6997_RS07910	COG2207	Transcriptional regulator
C6997_RS07915	COG3045	CreA protein
C6997_RS07920	COG0745	RESPONSE REGULATOR receiver
C6997_RS07925	COG2205	protein histidine kinase activity
C6997_RS07930	COG4452	Inner membrane protein CreD
C6997_RS07935	COG0745	RESPONSE REGULATOR receiver
C6997_RS07945	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
C6997_RS07955	COG0460	homoserine dehydrogenase
C6997_RS07955	COG0527	aspartate kinase activity
C6997_RS07965	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C6997_RS07980	COG1115	amino acid carrier protein
C6997_RS07990	COG0521	Mo-molybdopterin cofactor biosynthetic process
C6997_RS07995	COG1584	GPR1 FUN34 yaaH family protein
C6997_RS08000	COG4735	regulation of single-species biofilm formation
C6997_RS08030	COG0583	DNA-binding transcription factor activity
C6997_RS08060	COG0196	riboflavin kinase activity
C6997_RS08075	COG1047	Peptidyl-prolyl cis-trans
C6997_RS08100	COG0505	Belongs to the CarA family
C6997_RS08105	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C6997_RS08160	COG0644	oxidoreductase
C6997_RS08165	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C6997_RS08170	COG2271	Major facilitator Superfamily
C6997_RS08185	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C6997_RS08225	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C6997_RS08230	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
C6997_RS08235	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
C6997_RS08240	COG0564	pseudouridine synthase activity
C6997_RS08250	COG0417	DNA replication proofreading
C6997_RS08255	COG0235	Class ii aldolase
C6997_RS08275	COG4977	sequence-specific DNA binding
C6997_RS08280	COG0586	Pfam SNARE associated Golgi protein
C6997_RS08290	COG1178	ABC-type Fe3 transport system permease component
C6997_RS08295	COG4143	(ABC) transporter
C6997_RS08310	COG2814	Major facilitator Superfamily
C6997_RS08325	COG0473	3-isopropylmalate dehydrogenase activity
C6997_RS08340	COG0583	DNA-binding transcription factor activity
C6997_RS08345	COG0028	Belongs to the TPP enzyme family
C6997_RS08350	COG0440	acetolactate synthase activity
C6997_RS08360	COG1609	Transcriptional regulator
C6997_RS08385	COG3116	cell division
C6997_RS08390	COG0768	penicillin binding
C6997_RS08395	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C6997_RS08400	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C6997_RS08415	COG0772	Belongs to the SEDS family
C6997_RS08430	COG1181	Belongs to the D-alanine--D-alanine ligase family
C6997_RS08435	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C6997_RS08440	COG0849	cell division
C6997_RS08445	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C6997_RS08465	COG0494	nUDIX hydrolase
C6997_RS08475	COG3547	Transposase (IS116 IS110 IS902 family)
C6997_RS08490	COG0237	dephospho-CoA kinase activity
C6997_RS08500	COG1459	type II secretion system
C6997_RS08505	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C6997_RS08510	COG4969	Belongs to the N-Me-Phe pilin family
C6997_RS08520	COG0157	Belongs to the NadC ModD family
C6997_RS08525	COG3023	N-Acetylmuramoyl-L-alanine amidase
C6997_RS08530	COG3725	Membrane protein required for beta-lactamase induction
C6997_RS08535	COG1113	amino acid transport
C6997_RS08540	COG2186	Transcriptional regulator
C6997_RS08550	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
C6997_RS08555	COG0508	dehydrogenase complex catalyzes the overall conversion of
C6997_RS08560	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C6997_RS08565	COG3064	Membrane
C6997_RS08575	COG1049	propionate catabolic process, 2-methylcitrate cycle
C6997_RS08600	COG2132	Multicopper oxidase
C6997_RS08605	COG4993	Dehydrogenase
C6997_RS08610	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
C6997_RS08615	COG0288	reversible hydration of carbon dioxide
C6997_RS08620	COG1131	(ABC) transporter
C6997_RS08625	COG0842	Transport permease protein
C6997_RS08630	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6997_RS08635	COG0726	polysaccharide deacetylase
C6997_RS08650	COG5464	transposase or invertase
C6997_RS08670	COG3539	Fimbrial protein
C6997_RS08675	COG3539	Fimbrial protein
C6997_RS08680	COG3539	Fimbrial protein
C6997_RS08685	COG3188	usher protein
C6997_RS08690	COG3121	Chaperone
C6997_RS08695	COG3539	Fimbrial protein
C6997_RS08700	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C6997_RS08705	COG0617	tRNA 3'-terminal CCA addition
C6997_RS08715	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C6997_RS08725	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C6997_RS08730	COG1643	Atp-dependent helicase
C6997_RS08740	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C6997_RS08745	COG4774	siderophore transport
C6997_RS08750	COG1120	ATPase activity
C6997_RS08755	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C6997_RS08760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6997_RS08780	COG2860	membrane
C6997_RS08785	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C6997_RS08805	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C6997_RS08810	COG3835	regulator
C6997_RS08820	COG1408	metallophosphoesterase
C6997_RS08835	COG0024	Methionine aminopeptidase
C6997_RS08870	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C6997_RS08875	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C6997_RS08880	COG0575	Belongs to the CDS family
C6997_RS08885	COG0750	zinc metalloprotease
C6997_RS08895	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
C6997_RS08900	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C6997_RS08925	COG0587	DNA-directed DNA polymerase activity
C6997_RS08935	COG1982	Orn Lys Arg decarboxylase major
C6997_RS08940	COG0346	lactoylglutathione lyase activity
C6997_RS08950	COG4568	rho-dependent transcription termination
C6997_RS08960	COG4681	YaeQ
C6997_RS08965	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
C6997_RS08970	COG3015	lipoprotein NlpE involved in copper resistance
C6997_RS08985	COG1720	tRNA m6t6A37 methyltransferase activity
C6997_RS08995	COG1464	Belongs to the NlpA lipoprotein family
C6997_RS09000	COG2011	ABC-type metal ion transport system permease component
C6997_RS09005	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C6997_RS09010	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C6997_RS09045	COG0656	L-ascorbic acid biosynthetic process
C6997_RS09050	COG0583	DNA-binding transcription factor activity
C6997_RS09060	COG2226	methyltransferase
C6997_RS09065	COG1388	LysM domain
C6997_RS09065	COG0741	lytic transglycosylase activity
C6997_RS09075	COG2226	methyltransferase
C6997_RS09085	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6997_RS09110	COG4104	PAAR repeat-containing protein
C6997_RS09115	COG3157	Type VI secretion system effector, Hcp
C6997_RS09165	COG3209	COG3209 Rhs family protein
C6997_RS09185	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C6997_RS09195	COG1960	acyl-CoA dehydrogenase activity
C6997_RS09205	COG0121	glutamine amidotransferase
C6997_RS09210	COG3034	peptidoglycan biosynthetic process
C6997_RS09215	COG3041	Addiction module toxin RelE StbE family
C6997_RS09220	COG3077	Addiction module antitoxin, RelB DinJ family
C6997_RS09225	COG0791	NLP P60 protein
C6997_RS09255	COG1987	bacterial-type flagellum assembly
C6997_RS09280	COG1677	Flagellar hook-basal body complex protein FliE
C6997_RS09290	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C6997_RS09310	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C6997_RS09340	COG1815	bacterial-type flagellum-dependent cell motility
C6997_RS09345	COG1558	bacterial-type flagellum-dependent cell motility
C6997_RS09355	COG1749	Flagellar hook protein flgE
C6997_RS09360	COG4787	bacterial-type flagellum-dependent cell motility
C6997_RS09365	COG4786	Flagellar basal body rod
C6997_RS09390	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C6997_RS09405	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C6997_RS09415	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C6997_RS09440	COG1191	sigma factor activity
C6997_RS09445	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C6997_RS09460	COG0454	-acetyltransferase
C6997_RS09470	COG1690	Belongs to the RtcB family
C6997_RS09475	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
C6997_RS09480	COG2195	Cleaves the N-terminal amino acid of tripeptides
C6997_RS09500	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C6997_RS09595	COG0583	DNA-binding transcription factor activity
C6997_RS09600	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C6997_RS09605	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C6997_RS09610	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C6997_RS09615	COG2080	2 iron, 2 sulfur cluster binding
C6997_RS09625	COG3477	response to acidic pH
C6997_RS09635	COG0727	PFAM Uncharacterised protein family (UPF0153)
C6997_RS09640	COG3121	Chaperone
C6997_RS09650	COG3188	usher protein
C6997_RS09700	COG1388	LysM domain
C6997_RS09705	COG2207	Transcriptional regulator
C6997_RS09705	COG3708	Transcriptional regulator
C6997_RS09710	COG0656	L-ascorbic acid biosynthetic process
C6997_RS09715	COG3059	membrane
C6997_RS09725	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C6997_RS09730	COG2207	Transcriptional regulator
C6997_RS09735	COG0247	lactate metabolic process
C6997_RS09740	COG1139	Iron-sulfur cluster binding protein
C6997_RS09745	COG1556	Lactate utilization protein
C6997_RS09785	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C6997_RS09795	COG2771	luxR family
C6997_RS09795	COG2200	EAL domain
C6997_RS09800	COG0583	DNA-binding transcription factor activity
C6997_RS09815	COG0666	response to abiotic stimulus
C6997_RS09825	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C6997_RS09830	COG1304	FMN binding
C6997_RS09835	COG0549	Belongs to the carbamate kinase family
C6997_RS09840	COG0402	S-adenosylhomocysteine deaminase activity
C6997_RS09850	COG1879	ABC-type sugar transport system periplasmic component
C6997_RS09855	COG1129	ABC transporter
C6997_RS09860	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6997_RS09870	COG1064	alcohol dehydrogenase
C6997_RS09885	COG1280	lysine exporter protein (LysE YggA)
C6997_RS09895	COG3829	transcription factor binding
C6997_RS09900	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C6997_RS09905	COG0372	Belongs to the citrate synthase family
C6997_RS09910	COG2079	MmgE PrpD family protein
C6997_RS09915	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C6997_RS09920	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C6997_RS09925	COG0402	S-adenosylhomocysteine deaminase activity
C6997_RS09930	COG0583	DNA-binding transcription factor activity
C6997_RS09935	COG0288	reversible hydration of carbon dioxide
C6997_RS09945	COG2807	transmembrane transport
C6997_RS09950	COG2223	nitrite transmembrane transporter activity
C6997_RS09955	COG3250	beta-galactosidase activity
C6997_RS09965	COG1609	Transcriptional regulator
C6997_RS09970	COG1414	Transcriptional regulator
C6997_RS10005	COG2814	Major facilitator Superfamily
C6997_RS10010	COG3122	Protein conserved in bacteria
C6997_RS10040	COG1215	transferase activity, transferring glycosyl groups
C6997_RS10045	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C6997_RS10055	COG4521	taurine ABC transporter
C6997_RS10060	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
C6997_RS10065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C6997_RS10070	COG2175	clavaminate synthase activity
C6997_RS10075	COG0113	porphobilinogen synthase activity
C6997_RS10100	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C6997_RS10105	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C6997_RS10115	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
C6997_RS10140	COG1181	Belongs to the D-alanine--D-alanine ligase family
C6997_RS10155	COG1785	Belongs to the alkaline phosphatase family
C6997_RS10165	COG3706	GGDEF domain
C6997_RS10170	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C6997_RS10195	COG4126	flavin adenine dinucleotide binding
C6997_RS10220	COG1940	carbohydrate kinase activity
C6997_RS10225	COG2814	Major facilitator Superfamily
C6997_RS10230	COG0419	ATPase involved in DNA repair
C6997_RS10235	COG0420	3'-5' exonuclease activity
C6997_RS10240	COG0745	RESPONSE REGULATOR receiver
C6997_RS10245	COG5002	protein histidine kinase activity
C6997_RS10250	COG1114	Component of the transport system for branched-chain amino acids
C6997_RS10255	COG1113	amino acid transport
C6997_RS10260	COG0366	Alpha amylase catalytic
C6997_RS10280	COG1862	Preprotein translocase
C6997_RS10285	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C6997_RS10290	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C6997_RS10295	COG1403	HNH endonuclease
C6997_RS10300	COG3248	Nucleoside-binding outer membrane protein
C6997_RS10305	COG4238	major outer membrane lipoprotein
C6997_RS10315	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C6997_RS10315	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C6997_RS10330	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C6997_RS10335	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C6997_RS10340	COG0667	Aldo Keto reductase
C6997_RS10350	COG0142	geranyltranstransferase activity
C6997_RS10365	COG0693	protein deglycase activity
C6997_RS10370	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C6997_RS10380	COG2814	Major facilitator Superfamily
C6997_RS10405	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C6997_RS10410	COG1845	cytochrome c oxidase, subunit III
C6997_RS10415	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C6997_RS10420	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C6997_RS10425	COG2223	nitrite transmembrane transporter activity
C6997_RS10430	COG3056	Lipoprotein
C6997_RS10435	COG0271	Belongs to the BolA IbaG family
C6997_RS10460	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C6997_RS10465	COG0776	regulation of translation
C6997_RS10470	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C6997_RS10475	COG1555	photosystem II stabilization
C6997_RS10480	COG0824	Thioesterase
C6997_RS10490	COG4533	DNA binding
C6997_RS10500	COG1522	sequence-specific DNA binding
C6997_RS10505	COG1132	(ABC) transporter
C6997_RS10510	COG1132	(ABC) transporter
C6997_RS10515	COG0347	Belongs to the P(II) protein family
C6997_RS10520	COG0004	ammonium transporteR
C6997_RS10525	COG1946	Acyl-CoA thioesterase
C6997_RS10530	COG3126	Type III secretion system lipoprotein chaperone (YscW)
C6997_RS10535	COG3695	enzyme binding
C6997_RS10545	COG5507	3-demethylubiquinone-9 3-methyltransferase
C6997_RS10550	COG4943	cyclic-guanylate-specific phosphodiesterase activity
C6997_RS10560	COG0110	maltose O-acetyltransferase activity
C6997_RS10575	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C6997_RS10580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6997_RS10585	COG1309	transcriptional regulator
C6997_RS10595	COG1196	nuclear chromosome segregation
C6997_RS10595	COG3264	Mechanosensitive ion channel
C6997_RS10600	COG3547	Transposase (IS116 IS110 IS902 family)
C6997_RS10615	COG3923	Primosomal replication protein n
C6997_RS10620	COG2832	Protein of unknown function (DUF454)
C6997_RS10635	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C6997_RS10675	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6997_RS10680	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C6997_RS10680	COG4651	solute:proton antiporter activity
C6997_RS10685	COG2223	nitrite transmembrane transporter activity
C6997_RS10695	COG0737	Belongs to the 5'-nucleotidase family
C6997_RS10700	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C6997_RS10710	COG3735	TraB family
C6997_RS10720	COG3093	addiction module antidote protein HigA
C6997_RS10725	COG2217	Heavy metal translocating P-type atpase
C6997_RS10735	COG0531	amino acid
C6997_RS10740	COG0789	Transcriptional regulator
C6997_RS10745	COG1585	Membrane protein implicated in regulation of membrane protease activity
C6997_RS10750	COG0330	HflC and HflK could
C6997_RS10755	COG4619	ABC transporter
C6997_RS10760	COG0390	transport system, permease component
C6997_RS10765	COG3118	belongs to the thioredoxin family
C6997_RS10770	COG0300	oxidoreductase activity
C6997_RS10775	COG2755	lipolytic protein G-D-S-L family
C6997_RS10780	COG4181	ATPase activity
C6997_RS10785	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
C6997_RS10810	COG0583	DNA-binding transcription factor activity
C6997_RS10820	COG1414	Transcriptional regulator
C6997_RS10825	COG3960	tartronate-semialdehyde synthase activity
C6997_RS10830	COG3622	Belongs to the hyi family
C6997_RS10835	COG2084	Dehydrogenase
C6997_RS10840	COG1953	Uracil, thiamine, allantoin
C6997_RS10855	COG1929	Belongs to the glycerate kinase type-1 family
C6997_RS10860	COG3257	ureidoglycine aminohydrolase activity
C6997_RS10865	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C6997_RS10875	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C6997_RS10880	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C6997_RS10890	COG0549	Belongs to the carbamate kinase family
C6997_RS10895	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C6997_RS10900	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C6997_RS10915	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C6997_RS10925	COG1988	membrane-bound metal-dependent
C6997_RS10930	COG2501	S4 domain
C6997_RS10940	COG3539	Fimbrial protein
C6997_RS10945	COG3121	Chaperone
C6997_RS10950	COG3188	usher protein
C6997_RS10955	COG3539	Fimbrial protein
C6997_RS10960	COG3539	Fimbrial protein
C6997_RS10965	COG2197	response regulator
C6997_RS10975	COG0582	viral genome integration into host DNA
C6997_RS11140	COG3772	lysozyme
C6997_RS11170	COG4220	transposase activity
C6997_RS11195	COG4372	Transposase
C6997_RS11200	COG3436	PFAM IS66 Orf2 family protein
C6997_RS11260	COG1196	nuclear chromosome segregation
C6997_RS11295	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6997_RS11310	COG0500	methyltransferase
C6997_RS11325	COG4571	Outer membrane protease
C6997_RS11340	COG2207	Transcriptional regulator
C6997_RS11355	COG4783	chaperone-mediated protein folding
C6997_RS11360	COG1215	transferase activity, transferring glycosyl groups
C6997_RS11370	COG3209	COG3209 Rhs family protein
C6997_RS11370	COG4104	PAAR repeat-containing protein
C6997_RS11385	COG3209	COG3209 Rhs family protein
C6997_RS11385	COG4104	PAAR repeat-containing protein
C6997_RS11395	COG3501	Rhs element vgr protein
C6997_RS11400	COG5002	protein histidine kinase activity
C6997_RS11405	COG0745	RESPONSE REGULATOR receiver
C6997_RS11415	COG1538	Outer membrane efflux protein
C6997_RS11420	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6997_RS11425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6997_RS11430	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C6997_RS11435	COG1113	amino acid transport
C6997_RS11440	COG0668	transmembrane transport
C6997_RS11445	COG0778	Nitroreductase
C6997_RS11450	COG2315	Protein conserved in bacteria
C6997_RS11485	COG2977	Belongs to the P-Pant transferase superfamily
C6997_RS11490	COG4771	TonB-dependent receptor
C6997_RS11500	COG2382	esterase
C6997_RS11505	COG3251	PFAM MbtH domain protein
C6997_RS11510	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C6997_RS11510	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
C6997_RS11515	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
C6997_RS11520	COG1120	ATPase activity
C6997_RS11525	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6997_RS11530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6997_RS11540	COG4592	Periplasmic binding protein
C6997_RS11550	COG1169	isochorismate synthase
C6997_RS11555	COG1021	2,3-dihydroxybenzoate-AMP ligase
C6997_RS11560	COG3433	isochorismatase activity
C6997_RS11560	COG1535	isochorismatase
C6997_RS11565	COG1028	Short-chain dehydrogenase reductase Sdr
C6997_RS11570	COG2050	protein possibly involved in aromatic compounds catabolism
C6997_RS11575	COG1966	Carbon starvation protein
C6997_RS11580	COG2879	small protein
C6997_RS11585	COG0371	Dehydrogenase
C6997_RS11590	COG0436	Aminotransferase
C6997_RS11595	COG1475	DNA binding
C6997_RS11600	COG3969	phosphoadenosine phosphosulfate
C6997_RS11605	COG0583	DNA-binding transcription factor activity
C6997_RS11610	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C6997_RS11615	COG0450	alkyl hydroperoxide reductase
C6997_RS11620	COG3634	alkyl hydroperoxide reductase activity
C6997_RS11625	COG0589	response to stress
C6997_RS11630	COG1063	alcohol dehydrogenase
C6997_RS11640	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C6997_RS11650	COG3719	Belongs to the RNase T2 family
C6997_RS11655	COG0471	metal ion transport
C6997_RS11670	COG3051	citrate lyase alpha subunit
C6997_RS11675	COG2301	Belongs to the HpcH HpaI aldolase family
C6997_RS11685	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
C6997_RS11690	COG3290	protein histidine kinase activity
C6997_RS11695	COG4565	transcriptional regulatory protein
C6997_RS11700	COG3069	C4-dicarboxylate transmembrane transporter activity
C6997_RS11725	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C6997_RS11730	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C6997_RS11745	COG0583	DNA-binding transcription factor activity
C6997_RS11765	COG1686	Belongs to the peptidase S11 family
C6997_RS11770	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C6997_RS11775	COG0772	Belongs to the SEDS family
C6997_RS11780	COG0768	penicillin binding
C6997_RS11790	COG0799	negative regulation of ribosome biogenesis
C6997_RS11795	COG0406	alpha-ribazole phosphatase activity
C6997_RS11805	COG1466	dna polymerase III delta subunit
C6997_RS11820	COG2888	peptidyl-tyrosine sulfation
C6997_RS11825	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C6997_RS11835	COG2214	Heat shock protein DnaJ domain protein
C6997_RS11840	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C6997_RS11850	COG2214	Heat shock protein DnaJ domain protein
C6997_RS11855	COG0443	Heat shock 70 kDa protein
C6997_RS11865	COG1126	abc transporter atp-binding protein
C6997_RS11870	COG0765	amino acid transport
C6997_RS11875	COG0765	amino acid transport
C6997_RS11880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6997_RS11895	COG0815	Transfers the fatty acyl group on membrane lipoproteins
C6997_RS11900	COG4535	Mg2 and Co2 transporter CorC
C6997_RS11910	COG1702	phosphate starvation-inducible protein PhoH
C6997_RS11920	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C6997_RS11960	COG0367	asparagine synthase
C6997_RS11970	COG0647	UMP catabolic process
C6997_RS11975	COG1846	Transcriptional regulator
C6997_RS11975	COG1940	carbohydrate kinase activity
C6997_RS11980	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C6997_RS11990	COG1263	PTS System
C6997_RS11990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6997_RS11990	COG2190	(PTS) system
C6997_RS12015	COG0735	belongs to the Fur family
C6997_RS12025	COG0716	FMN binding
C6997_RS12035	COG0596	Alpha beta hydrolase
C6997_RS12040	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
C6997_RS12045	COG0033	Phosphoglucomutase
C6997_RS12050	COG0531	amino acid
C6997_RS12055	COG1982	Orn Lys Arg decarboxylase major
C6997_RS12070	COG0745	RESPONSE REGULATOR receiver
C6997_RS12075	COG2205	protein histidine kinase activity
C6997_RS12105	COG3209	COG3209 Rhs family protein
C6997_RS12130	COG3272	Protein of unknown function (DUF1722)
C6997_RS12135	COG0415	Belongs to the DNA photolyase family
C6997_RS12145	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C6997_RS12150	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C6997_RS12155	COG1984	allophanate hydrolase subunit 2
C6997_RS12170	COG3180	Ammonia monooxygenase
C6997_RS12175	COG3539	Fimbrial protein
C6997_RS12180	COG3121	Chaperone
C6997_RS12185	COG3188	usher protein
C6997_RS12195	COG0372	Belongs to the citrate synthase family
C6997_RS12210	COG2009	succinate dehydrogenase
C6997_RS12215	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
C6997_RS12220	COG1053	succinate dehydrogenase
C6997_RS12225	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C6997_RS12230	COG0567	Dehydrogenase, E1 component
C6997_RS12235	COG0508	dehydrogenase complex catalyzes the overall conversion of
C6997_RS12245	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C6997_RS12250	COG2188	Transcriptional regulator
C6997_RS12260	COG0383	alpha-mannosidase activity
C6997_RS12270	COG1271	oxidase subunit
C6997_RS12275	COG1294	oxidase, subunit
C6997_RS12280	COG4890	Cyd operon protein YbgT
C6997_RS12285	COG3790	cyd operon protein YbgE
C6997_RS12290	COG0824	Thioesterase
C6997_RS12295	COG0811	peptide transport
C6997_RS12300	COG0848	biopolymer transport protein
C6997_RS12305	COG3064	Membrane
C6997_RS12315	COG2885	chlorophyll binding
C6997_RS12320	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
C6997_RS12370	COG3201	nicotinamide mononucleotide transporter
C6997_RS12375	COG1230	cation diffusion facilitator family transporter
C6997_RS12390	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C6997_RS12400	COG2017	converts alpha-aldose to the beta-anomer
C6997_RS12410	COG1085	galactose-1-phosphate uridylyltransferase
C6997_RS12415	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C6997_RS12420	COG1119	ATPase activity
C6997_RS12425	COG2005	Transcriptional regulator
C6997_RS12425	COG3585	molybdate ion transport
C6997_RS12440	COG0725	ABC transporter, periplasmic molybdate-binding protein
C6997_RS12445	COG4149	molybdate abc transporter
C6997_RS12455	COG0561	phosphatase activity
C6997_RS12465	COG0583	DNA-binding transcription factor activity
C6997_RS12470	COG2828	Protein conserved in bacteria
C6997_RS12475	COG0471	metal ion transport
C6997_RS12480	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C6997_RS12485	COG4677	pectinesterase activity
C6997_RS12490	COG0582	viral genome integration into host DNA
C6997_RS12710	COG3772	lysozyme
C6997_RS12735	COG4220	transposase activity
C6997_RS12765	COG3436	PFAM IS66 Orf2 family protein
C6997_RS12770	COG4372	Transposase
C6997_RS12860	COG4372	Transposase
C6997_RS12865	COG3436	PFAM IS66 Orf2 family protein
C6997_RS12900	COG1881	PFAM PEBP family protein
C6997_RS12905	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C6997_RS12920	COG2226	methyltransferase
C6997_RS12925	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C6997_RS12935	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C6997_RS12945	COG0521	Mo-molybdopterin cofactor biosynthetic process
C6997_RS12955	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C6997_RS12960	COG0314	molybdopterin synthase activity
C6997_RS12965	COG0670	Belongs to the BI1 family
C6997_RS12970	COG0670	Belongs to the BI1 family
C6997_RS12975	COG0392	lysyltransferase activity
C6997_RS12980	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C6997_RS12985	COG3568	Endonuclease Exonuclease Phosphatase
C6997_RS12995	COG0842	Transport permease protein
C6997_RS13000	COG0842	Transport permease protein
C6997_RS13005	COG1131	(ABC) transporter
C6997_RS13015	COG1309	transcriptional regulator
C6997_RS13020	COG0513	Belongs to the DEAD box helicase family
C6997_RS13025	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
C6997_RS13030	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C6997_RS13035	COG1199	ATP-dependent helicase activity
C6997_RS13045	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
C6997_RS13055	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C6997_RS13065	COG4774	siderophore transport
C6997_RS13080	COG0668	transmembrane transport
C6997_RS13085	COG1126	abc transporter atp-binding protein
C6997_RS13090	COG0765	amino acid transport
C6997_RS13095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6997_RS13115	COG5006	permease, DMT superfamily
C6997_RS13120	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
C6997_RS13125	COG2194	sulfuric ester hydrolase activity
C6997_RS13135	COG1321	iron dependent repressor
C6997_RS13140	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C6997_RS13145	COG1376	ErfK ybiS ycfS ynhG family protein
C6997_RS13150	COG0488	(ABC) transporter
C6997_RS13160	COG3547	Transposase (IS116 IS110 IS902 family)
C6997_RS13170	COG0561	phosphatase activity
C6997_RS13175	COG1882	Formate acetyltransferase
C6997_RS13180	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C6997_RS13185	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C6997_RS13190	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C6997_RS13195	COG0303	'Molybdopterin
C6997_RS13200	COG1446	asparaginase
C6997_RS13225	COG2200	EAL domain
C6997_RS13230	COG2199	diguanylate cyclase activity
C6997_RS13245	COG2133	pyrroloquinoline quinone binding
C6997_RS13250	COG0625	glutathione transferase activity
C6997_RS13255	COG1686	Belongs to the peptidase S11 family
C6997_RS13260	COG1349	DNA-binding transcription factor activity
C6997_RS13265	COG0671	phosphoesterase, PA-phosphatase related
C6997_RS13270	COG2814	Major facilitator Superfamily
C6997_RS13280	COG0561	phosphatase activity
C6997_RS13285	COG0738	Major facilitator superfamily
C6997_RS13290	COG3226	Transcriptional regulator
C6997_RS13305	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C6997_RS13315	COG0778	Nitroreductase
C6997_RS13335	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C6997_RS13340	COG3842	ATPase activity
C6997_RS13345	COG1176	ABC-type spermidine putrescine transport system, permease component I
C6997_RS13350	COG1177	transmembrane transport
C6997_RS13365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6997_RS13370	COG4160	amino acid transport
C6997_RS13375	COG4215	(ABC) transporter
C6997_RS13380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6997_RS13385	COG1126	abc transporter atp-binding protein
C6997_RS13400	COG3023	N-Acetylmuramoyl-L-alanine amidase
C6997_RS13405	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C6997_RS13410	COG0702	epimerase
C6997_RS13415	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
C6997_RS13420	COG0028	Belongs to the TPP enzyme family
C6997_RS13425	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C6997_RS13435	COG2431	L-lysine efflux transmembrane transporter activity
C6997_RS13450	COG3593	DNA synthesis involved in DNA repair
C6997_RS13455	COG2990	Protein conserved in bacteria
C6997_RS13460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6997_RS13465	COG0577	efflux transmembrane transporter activity
C6997_RS13465	COG1136	(ABC) transporter
C6997_RS13470	COG1278	Cold shock
C6997_RS13480	COG0542	response to heat
C6997_RS13500	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C6997_RS13505	COG4988	ABC transporter
C6997_RS13510	COG0492	ferredoxin-NADP+ reductase activity
C6997_RS13520	COG1522	sequence-specific DNA binding
C6997_RS13535	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C6997_RS13545	COG0243	molybdopterin cofactor binding
C6997_RS13550	COG0437	4 iron, 4 sulfur cluster binding
C6997_RS13555	COG3302	dmso reductase anchor subunit
C6997_RS13560	COG1335	isochorismatase
C6997_RS13570	COG0531	amino acid
C6997_RS13575	COG0583	DNA-binding transcription factor activity
C6997_RS13580	COG2249	NAD(P)H dehydrogenase (quinone) activity
C6997_RS13585	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C6997_RS13590	COG1882	Formate acetyltransferase
C6997_RS13595	COG2116	formate transmembrane transporter activity
C6997_RS13600	COG1944	ATP diphosphatase activity
C6997_RS13605	COG2323	membrane
C6997_RS13620	COG0501	Belongs to the peptidase M48B family
C6997_RS13630	COG0539	negative regulation of cytoplasmic translation
C6997_RS13640	COG2333	competence protein COMEC
C6997_RS13640	COG0658	competence protein
C6997_RS13645	COG1132	(ABC) transporter
C6997_RS13655	COG3214	Protein conserved in bacteria
C6997_RS13670	COG3173	Aminoglycoside phosphotransferase
C6997_RS13675	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C6997_RS13680	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C6997_RS13690	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
C6997_RS13700	COG2989	Protein conserved in bacteria
C6997_RS13710	COG3108	Peptidase M15
C6997_RS13715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C6997_RS13720	COG3547	Transposase (IS116 IS110 IS902 family)
C6997_RS13730	COG1448	Aminotransferase
C6997_RS13750	COG0308	aminopeptidase N
C6997_RS13760	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C6997_RS13770	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C6997_RS13775	COG0431	NADPH-dependent FMN reductase
C6997_RS13785	COG3539	Fimbrial protein
C6997_RS13790	COG3121	Chaperone
C6997_RS13795	COG3188	usher protein
C6997_RS13800	COG3539	Fimbrial protein
C6997_RS13805	COG3539	Fimbrial protein
C6997_RS13810	COG3539	Fimbrial protein
C6997_RS13815	COG3121	Chaperone
C6997_RS13830	COG3217	Mosc domain protein beta barrel domain protein
C6997_RS13830	COG0633	Ferredoxin
C6997_RS13840	COG0488	(ABC) transporter
C6997_RS13845	COG2995	paraquat-inducible protein a
C6997_RS13850	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C6997_RS13850	COG3008	intermembrane lipid transfer
C6997_RS13855	COG3009	Protein conserved in bacteria
C6997_RS13860	COG3130	regulation of translation
C6997_RS13870	COG1067	ATP-dependent peptidase activity
C6997_RS13880	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
C6997_RS13880	COG2885	chlorophyll binding
C6997_RS13895	COG3070	regulator of competence-specific genes
C6997_RS13900	COG1289	transmembrane transporter activity
C6997_RS13905	COG3304	Inner membrane component domain
C6997_RS13910	COG0210	DNA helicase
C6997_RS13925	COG1832	CoA-binding protein
C6997_RS13940	COG1254	Belongs to the acylphosphatase family
C6997_RS13945	COG2920	part of a sulfur-relay system
C6997_RS13950	COG0670	Belongs to the BI1 family
C6997_RS13965	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6997_RS14035	COG1846	Transcriptional regulator
C6997_RS14105	COG1403	HNH endonuclease
C6997_RS14110	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C6997_RS14125	COG2207	Transcriptional regulator
C6997_RS14180	COG3772	lysozyme
C6997_RS14310	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6997_RS14325	COG3436	PFAM IS66 Orf2 family protein
C6997_RS14330	COG4372	Transposase
C6997_RS14365	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
C6997_RS14370	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
C6997_RS14375	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
C6997_RS14380	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C6997_RS14385	COG1999	signal sequence binding
C6997_RS14390	COG1773	rubredoxin
C6997_RS14400	COG1294	oxidase, subunit
C6997_RS14410	COG3547	Transposase (IS116 IS110 IS902 family)
C6997_RS14425	COG0489	protein tyrosine kinase activity
C6997_RS14425	COG3206	protein involved in exopolysaccharide biosynthesis
C6997_RS14430	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C6997_RS14435	COG1596	polysaccharide export
C6997_RS14440	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C6997_RS14460	COG1278	Cold shock
C6997_RS14465	COG1278	Cold shock
C6997_RS14485	COG0348	domain, Protein
C6997_RS14490	COG2198	Histidine kinase
C6997_RS14490	COG2205	protein histidine kinase activity
C6997_RS14490	COG0784	Response regulator, receiver
C6997_RS14495	COG1879	ABC-type sugar transport system periplasmic component
C6997_RS14500	COG0745	RESPONSE REGULATOR receiver
C6997_RS14505	COG3005	denitrification pathway
C6997_RS14510	COG0243	molybdopterin cofactor binding
C6997_RS14555	COG3729	General stress protein
C6997_RS14560	COG2233	PERMEase
C6997_RS14595	COG1309	transcriptional regulator
C6997_RS14600	COG0506	proline dehydrogenase activity
C6997_RS14600	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C6997_RS14600	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C6997_RS14615	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C6997_RS14635	COG2822	iron ion transport
C6997_RS14645	COG1702	phosphate starvation-inducible protein PhoH
C6997_RS14665	COG0582	viral genome integration into host DNA
C6997_RS14695	COG4983	Phage plasmid primase, P4 family domain protein
C6997_RS14720	COG4372	Transposase
C6997_RS14725	COG3436	PFAM IS66 Orf2 family protein
C6997_RS14770	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C6997_RS14775	COG2194	sulfuric ester hydrolase activity
C6997_RS14790	COG0829	nickel cation binding
C6997_RS14835	COG0254	rRNA binding
C6997_RS14880	COG3436	PFAM IS66 Orf2 family protein
C6997_RS14885	COG4372	Transposase
C6997_RS14925	COG1358	cellular component organization or biogenesis
C6997_RS14990	COG4771	TonB-dependent receptor
C6997_RS15090	COG2831	hemolysin activation secretion protein
C6997_RS15100	COG3969	phosphoadenosine phosphosulfate
C6997_RS15105	COG3969	phosphoadenosine phosphosulfate
C6997_RS15110	COG1475	DNA binding
C6997_RS15200	COG3468	outer membrane autotransporter barrel domain protein
C6997_RS15240	COG2003	Belongs to the UPF0758 family
C6997_RS15290	COG3381	protein complex oligomerization
C6997_RS15300	COG1462	curli production assembly transport component CsgG
C6997_RS15315	COG2197	response regulator
C6997_RS15350	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C6997_RS15355	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C6997_RS15380	COG2943	transferase activity, transferring hexosyl groups
C6997_RS15385	COG5645	(Lipo)protein
C6997_RS15400	COG1560	Kdo2-lipid A biosynthetic process
C6997_RS15410	COG2353	YceI-like domain
C6997_RS15415	COG3038	cytochrome b561
C6997_RS15455	COG2999	glutathione oxidoreductase activity
C6997_RS15465	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C6997_RS15475	COG0673	inositol 2-dehydrogenase activity
C6997_RS15480	COG0728	peptidoglycan biosynthetic process
C6997_RS15485	COG3418	PFAM FlgN family protein
C6997_RS15490	COG2747	anti-sigma28 factor FlgM
C6997_RS15495	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
C6997_RS15500	COG1815	bacterial-type flagellum-dependent cell motility
C6997_RS15505	COG1558	bacterial-type flagellum-dependent cell motility
C6997_RS15510	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C6997_RS15515	COG1749	Flagellar hook protein flgE
C6997_RS15520	COG4787	bacterial-type flagellum-dependent cell motility
C6997_RS15525	COG4786	Flagellar basal body rod
C6997_RS15540	COG3951	Flagellar rod assembly protein muramidase FlgJ
C6997_RS15540	COG1705	Flagellar rod assembly protein muramidase FlgJ
C6997_RS15545	COG1256	bacterial-type flagellum assembly
C6997_RS15550	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C6997_RS15555	COG1530	ribonuclease E activity
C6997_RS15565	COG0564	pseudouridine synthase activity
C6997_RS15570	COG0424	maF-like protein
C6997_RS15575	COG1399	metal-binding, possibly nucleic acid-binding protein
C6997_RS15595	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C6997_RS15600	COG1028	Short-chain dehydrogenase reductase Sdr
C6997_RS15610	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C6997_RS15615	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C6997_RS15620	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C6997_RS15630	COG0470	DNA polymerase III
C6997_RS15635	COG0084	hydrolase, TatD family'
C6997_RS15640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6997_RS15640	COG1263	PTS System
C6997_RS15645	COG4773	Receptor
C6997_RS15650	COG0537	adenosine 5'-monophosphoramidase activity
C6997_RS15655	COG5633	Lipoprotein
C6997_RS15660	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
C6997_RS15680	COG1252	NADH dehydrogenase
C6997_RS15690	COG3134	Outer membrane lipoprotein
C6997_RS15695	COG1309	transcriptional regulator
C6997_RS15705	COG1388	LysM domain
C6997_RS15705	COG1376	ErfK ybiS ycfS ynhG family protein
C6997_RS15710	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C6997_RS15715	COG4763	Acyl-transferase
C6997_RS15720	COG4591	ABC-type transport system involved in lipoprotein release permease component
C6997_RS15725	COG1136	(ABC) transporter
C6997_RS15730	COG4591	ABC-type transport system involved in lipoprotein release permease component
C6997_RS15740	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C6997_RS15755	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C6997_RS15760	COG1177	transmembrane transport
C6997_RS15775	COG0582	viral genome integration into host DNA
C6997_RS15815	COG4197	protein conserved in bacteria, prophage-related
C6997_RS15830	COG1484	DNA-dependent DNA replication
C6997_RS15835	COG1846	Transcriptional regulator
C6997_RS15870	COG3111	PFAM Bacterial OB fold (BOF) protein
C6997_RS15880	COG1403	HNH endonuclease
C6997_RS15885	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C6997_RS15890	COG0484	heat shock protein binding
C6997_RS15930	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6997_RS16005	COG1484	DNA-dependent DNA replication
C6997_RS16010	COG1846	Transcriptional regulator
C6997_RS16035	COG1403	HNH endonuclease
C6997_RS16040	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C6997_RS16060	COG2207	Transcriptional regulator
C6997_RS16115	COG3772	lysozyme
C6997_RS16165	COG3436	PFAM IS66 Orf2 family protein
C6997_RS16170	COG4372	Transposase
C6997_RS16270	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6997_RS16335	COG2850	peptidyl-arginine hydroxylation
C6997_RS16465	COG4626	Terminase
C6997_RS16465	COG1802	Transcriptional regulator
C6997_RS16475	COG2205	protein histidine kinase activity
C6997_RS16485	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C6997_RS16505	COG1187	pseudouridine synthase activity
C6997_RS16510	COG0538	isocitrate dehydrogenase activity
C6997_RS16520	COG5562	phage envelope protein
C6997_RS16525	COG0789	Transcriptional regulator
C6997_RS16530	COG2200	EAL domain
C6997_RS16555	COG2200	EAL domain
C6997_RS16615	COG2894	cell division
C6997_RS16650	COG0179	Fumarylacetoacetate (FAA) hydrolase
C6997_RS16665	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C6997_RS16670	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C6997_RS16690	COG2719	SpoVR family
C6997_RS16700	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C6997_RS16715	COG1619	proteins homologs of microcin C7 resistance protein MccF
C6997_RS16730	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
C6997_RS16755	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C6997_RS16755	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
C6997_RS16755	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6997_RS16760	COG1461	Dihydroxyacetone kinase
C6997_RS16765	COG2376	Dihydroxyacetone kinase
C6997_RS16770	COG3284	Transcriptional regulator
C6997_RS16775	COG3468	outer membrane autotransporter barrel domain protein
C6997_RS16790	COG0012	GTP binding
C6997_RS16805	COG0659	secondary active sulfate transmembrane transporter activity
C6997_RS16815	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C6997_RS16845	COG2890	protein-(glutamine-N5) methyltransferase activity
C6997_RS16850	COG3094	Invasion gene expression up-regulator, SirB
C6997_RS16855	COG2912	Transglutaminase-like superfamily
C6997_RS16885	COG0387	Pfam Sodium calcium exchanger
C6997_RS16890	COG4572	Cation transport regulator
C6997_RS16895	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
C6997_RS16900	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
C6997_RS16905	COG4932	domain protein
C6997_RS16910	COG2197	response regulator
C6997_RS16915	COG3850	Histidine kinase
C6997_RS16925	COG2223	nitrite transmembrane transporter activity
C6997_RS16930	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C6997_RS16935	COG1140	nitrate reductase beta subunit
C6997_RS16940	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C6997_RS16945	COG2181	nitrate reductase activity
C6997_RS16960	COG0788	formyltetrahydrofolate deformylase activity
C6997_RS16970	COG1752	Esterase of the alpha-beta hydrolase superfamily
C6997_RS16975	COG0745	RESPONSE REGULATOR receiver
C6997_RS16980	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C6997_RS16990	COG1435	thymidine kinase activity
C6997_RS17000	COG1454	alcohol dehydrogenase
C6997_RS17000	COG1012	belongs to the aldehyde dehydrogenase family
C6997_RS17005	COG2095	MarC family integral membrane protein
C6997_RS17015	COG4166	transmembrane transport
C6997_RS17020	COG0601	transmembrane transport
C6997_RS17025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C6997_RS17030	COG0444	Belongs to the ABC transporter superfamily
C6997_RS17035	COG4608	Belongs to the ABC transporter superfamily
C6997_RS17055	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C6997_RS17060	COG2350	Protein conserved in bacteria
C6997_RS17090	COG1607	acyl-coa hydrolase
C6997_RS17110	COG3047	cAMP biosynthetic process
C6997_RS17115	COG0582	viral genome integration into host DNA
C6997_RS17125	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6997_RS17165	COG1396	sequence-specific DNA binding
C6997_RS17220	COG1403	HNH endonuclease
C6997_RS17225	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C6997_RS17280	COG3772	lysozyme
C6997_RS17420	COG3436	PFAM IS66 Orf2 family protein
C6997_RS17425	COG4372	Transposase
C6997_RS17440	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6997_RS17445	COG4372	Transposase
C6997_RS17450	COG3436	PFAM IS66 Orf2 family protein
C6997_RS17550	COG3685	Protein conserved in bacteria
C6997_RS17555	COG3685	Protein conserved in bacteria
C6997_RS17560	COG3729	General stress protein
C6997_RS17575	COG0134	indole-3-glycerol-phosphate synthase activity
C6997_RS17575	COG0135	phosphoribosylanthranilate isomerase activity
C6997_RS17580	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C6997_RS17580	COG0512	Glutamine amidotransferase of anthranilate synthase
C6997_RS17585	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C6997_RS17595	COG0613	PHP domain protein
C6997_RS17600	COG0009	L-threonylcarbamoyladenylate synthase
C6997_RS17605	COG1187	pseudouridine synthase activity
C6997_RS17610	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
C6997_RS17615	COG1028	Short-chain dehydrogenase reductase Sdr
C6997_RS17620	COG0616	signal peptide processing
C6997_RS17635	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C6997_RS17645	COG0583	DNA-binding transcription factor activity
C6997_RS17665	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C6997_RS17675	COG0671	phosphoesterase, PA-phosphatase related
C6997_RS17680	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
C6997_RS17685	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
C6997_RS17695	COG0023	Translation Initiation Factor
C6997_RS17705	COG1349	DNA-binding transcription factor activity
C6997_RS17715	COG5001	Diguanylate cyclase
C6997_RS17730	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C6997_RS17730	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C6997_RS17735	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C6997_RS17740	COG2852	Protein conserved in bacteria
C6997_RS17745	COG4172	Belongs to the ABC transporter superfamily
C6997_RS17750	COG4172	Belongs to the ABC transporter superfamily
C6997_RS17755	COG4171	peptide transport system, permease
C6997_RS17760	COG4168	peptide transport system, permease
C6997_RS17765	COG4166	transmembrane transport
C6997_RS17780	COG0531	amino acid
C6997_RS17785	COG0174	glutamine synthetase
C6997_RS17790	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C6997_RS17795	COG1917	Cupin 2, conserved barrel domain protein
C6997_RS17795	COG1396	sequence-specific DNA binding
C6997_RS17805	COG1012	belongs to the aldehyde dehydrogenase family
C6997_RS17810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C6997_RS17815	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C6997_RS17820	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C6997_RS17825	COG1842	Phage shock protein A
C6997_RS17835	COG1983	PspC domain protein
C6997_RS17845	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C6997_RS17855	COG1653	transport
C6997_RS17860	COG1175	transmembrane transport
C6997_RS17865	COG0395	ABC-type sugar transport system, permease component
C6997_RS17870	COG1063	alcohol dehydrogenase
C6997_RS17875	COG1082	Xylose isomerase domain protein TIM barrel
C6997_RS17880	COG0673	inositol 2-dehydrogenase activity
C6997_RS17885	COG1554	hydrolase, family 65, central catalytic
C6997_RS17890	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C6997_RS17895	COG3842	ATPase activity
C6997_RS17905	COG1609	Transcriptional regulator
C6997_RS17910	COG3106	COG3106 Predicted ATPase
C6997_RS17920	COG3283	Transcriptional regulator of aromatic amino acids metabolism
C6997_RS17925	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
C6997_RS17930	COG4948	Mandelate Racemase Muconate Lactonizing
C6997_RS17935	COG2866	Carboxypeptidase
C6997_RS17940	COG0702	epimerase
C6997_RS17945	COG1073	alpha beta
C6997_RS17950	COG1073	alpha beta
C6997_RS17955	COG0583	DNA-binding transcription factor activity
C6997_RS17960	COG4166	transmembrane transport
C6997_RS17965	COG0668	transmembrane transport
C6997_RS17970	COG3182	Iron-regulated membrane protein
C6997_RS17975	COG0589	response to stress
C6997_RS17980	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C6997_RS17985	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C6997_RS17990	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
C6997_RS18000	COG1473	amidohydrolase
C6997_RS18005	COG1473	amidohydrolase
C6997_RS18010	COG0583	DNA-binding transcription factor activity
C6997_RS18015	COG2840	Smr protein MutS2
C6997_RS18020	COG3706	GGDEF domain
C6997_RS18035	COG0513	Belongs to the DEAD box helicase family
C6997_RS18045	COG0582	viral genome integration into host DNA
C6997_RS18065	COG3723	Recombinational DNA repair protein, rece pathway
C6997_RS18070	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6997_RS18120	COG1484	DNA-dependent DNA replication
C6997_RS18125	COG1846	Transcriptional regulator
C6997_RS18195	COG1403	HNH endonuclease
C6997_RS18200	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C6997_RS18205	COG0484	heat shock protein binding
C6997_RS18235	COG3772	lysozyme
C6997_RS18265	COG4220	transposase activity
C6997_RS18285	COG1030	water channel activity
C6997_RS18370	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6997_RS18400	COG0477	Major facilitator Superfamily
C6997_RS18405	COG0246	Mannitol dehydrogenase
C6997_RS18415	COG1802	Transcriptional regulator
C6997_RS18420	COG4221	oxidoreductase activity
C6997_RS18430	COG0339	signal peptide processing
C6997_RS18440	COG1546	Belongs to the CinA family
C6997_RS18445	COG3111	PFAM Bacterial OB fold (BOF) protein
C6997_RS18470	COG2814	Major facilitator Superfamily
C6997_RS18475	COG0697	spore germination
C6997_RS18480	COG2188	Transcriptional regulator
C6997_RS18490	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C6997_RS18495	COG1447	Phosphotransferase system cellobiose-specific component IIA
C6997_RS18505	COG2723	6-phospho-beta-galactosidase activity
C6997_RS18515	COG4977	sequence-specific DNA binding
C6997_RS18520	COG1846	Transcriptional regulator
C6997_RS18545	COG0583	DNA-binding transcription factor activity
C6997_RS18550	COG1012	belongs to the aldehyde dehydrogenase family
C6997_RS18555	COG2066	Belongs to the glutaminase family
C6997_RS18570	COG2199	diguanylate cyclase activity
C6997_RS18590	COG3781	membrane
C6997_RS18640	COG1396	sequence-specific DNA binding
C6997_RS18645	COG3550	peptidyl-serine autophosphorylation
C6997_RS18665	COG3539	Fimbrial protein
C6997_RS18675	COG3188	usher protein
C6997_RS18680	COG3539	Fimbrial protein
C6997_RS18685	COG3539	Fimbrial protein
C6997_RS18690	COG3539	Fimbrial protein
C6997_RS18700	COG0243	molybdopterin cofactor binding
C6997_RS18710	COG2207	Transcriptional regulator
C6997_RS18715	COG3119	arylsulfatase activity
C6997_RS18725	COG4178	(ABC) transporter
C6997_RS18730	COG4771	TonB-dependent receptor
C6997_RS18735	COG0612	Peptidase, M16
C6997_RS18740	COG0076	glutamate decarboxylase activity
C6997_RS18745	COG0531	amino acid
C6997_RS18750	COG1649	PFAM Uncharacterised BCR, COG1649
C6997_RS18760	COG2199	diguanylate cyclase activity
C6997_RS18760	COG2200	EAL domain
C6997_RS18760	COG2202	Pas domain
C6997_RS18765	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
C6997_RS18770	COG0747	negative chemotaxis
C6997_RS18780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C6997_RS18785	COG0444	Belongs to the ABC transporter superfamily
C6997_RS18790	COG4608	Belongs to the ABC transporter superfamily
C6997_RS18795	COG1764	response to oxidative stress
C6997_RS18820	COG1064	alcohol dehydrogenase
C6997_RS18825	COG3093	addiction module antidote protein HigA
C6997_RS18830	COG2864	formate dehydrogenase
C6997_RS18835	COG0437	4 iron, 4 sulfur cluster binding
C6997_RS18845	COG0697	spore germination
C6997_RS18850	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C6997_RS18855	COG4886	Leucine-rich repeat (LRR) protein
C6997_RS18860	COG2223	nitrite transmembrane transporter activity
C6997_RS18865	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C6997_RS18870	COG1140	nitrate reductase beta subunit
C6997_RS18875	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C6997_RS18880	COG2181	nitrate reductase activity
C6997_RS18885	COG0384	phenazine biosynthesis protein PhzF
C6997_RS18890	COG2162	N-hydroxyarylamine O-acetyltransferase activity
C6997_RS18895	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C6997_RS18925	COG3209	COG3209 Rhs family protein
C6997_RS18940	COG0625	glutathione transferase activity
C6997_RS18945	COG1113	amino acid transport
C6997_RS18950	COG3391	amine dehydrogenase activity
C6997_RS18965	COG4772	TonB-dependent receptor
C6997_RS18970	COG1802	Transcriptional regulator
C6997_RS18975	COG2130	NADP-dependent
C6997_RS18985	COG1247	-acetyltransferase
C6997_RS18990	COG3238	Protein conserved in bacteria
C6997_RS19025	COG1177	transmembrane transport
C6997_RS19030	COG1176	ABC-type spermidine putrescine transport system, permease component I
C6997_RS19035	COG3842	ATPase activity
C6997_RS19040	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C6997_RS19050	COG1598	PFAM Uncharacterised protein family UPF0150
C6997_RS19055	COG1724	mRNA binding
C6997_RS19065	COG0826	peptidase U32
C6997_RS19070	COG1396	sequence-specific DNA binding
C6997_RS19075	COG3135	benzoate transporter
C6997_RS19080	COG0675	Transposase, IS605 OrfB family
C6997_RS19095	COG0500	methyltransferase
C6997_RS19100	COG1275	C4-dicarboxylate transporter malic acid transport protein
C6997_RS19105	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C6997_RS19110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C6997_RS19115	COG2841	Protein conserved in bacteria
C6997_RS19135	COG5383	Protein conserved in bacteria
C6997_RS19140	COG0583	DNA-binding transcription factor activity
C6997_RS19145	COG0840	transmembrane signaling receptor activity
C6997_RS19160	COG3038	cytochrome b561
C6997_RS19165	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C6997_RS19170	COG1012	belongs to the aldehyde dehydrogenase family
C6997_RS19175	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C6997_RS19180	COG1643	Atp-dependent helicase
C6997_RS19190	COG2453	phosphatase
C6997_RS19190	COG0671	phosphoesterase, PA-phosphatase related
C6997_RS19195	COG2267	carboxylic ester hydrolase activity
C6997_RS19200	COG4589	Belongs to the CDS family
C6997_RS19205	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C6997_RS19215	COG0667	Aldo Keto reductase
C6997_RS19220	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C6997_RS19225	COG3327	negative regulation of DNA-templated transcription, initiation
C6997_RS19230	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
C6997_RS19235	COG0183	Belongs to the thiolase family
C6997_RS19240	COG2050	protein possibly involved in aromatic compounds catabolism
C6997_RS19245	COG1250	3-hydroxyacyl-CoA dehydrogenase
C6997_RS19250	COG1024	Enoyl-CoA hydratase
C6997_RS19255	COG1024	Enoyl-CoA hydratase
C6997_RS19260	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C6997_RS19265	COG2151	metal-sulfur cluster biosynthetic enzyme
C6997_RS19270	COG3396	Phenylacetate-CoA oxygenase
C6997_RS19275	COG3460	Phenylacetate-CoA oxygenase
C6997_RS19280	COG3396	Phenylacetate-CoA oxygenase
C6997_RS19285	COG2030	dehydratase
C6997_RS19285	COG1012	belongs to the aldehyde dehydrogenase family
C6997_RS19290	COG3733	amine oxidase
C6997_RS19295	COG1012	belongs to the aldehyde dehydrogenase family
C6997_RS19300	COG2207	Transcriptional regulator
C6997_RS19305	COG3784	Protein of unknown function (DUF1318)
C6997_RS19315	COG2911	Protein conserved in bacteria
C6997_RS19320	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C6997_RS19325	COG3187	Heat shock protein
C6997_RS19330	COG3042	response to heat
C6997_RS19335	COG1013	pyruvate-flavodoxin oxidoreductase activity
C6997_RS19335	COG0674	pyruvate-flavodoxin oxidoreductase activity
C6997_RS19335	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
C6997_RS19335	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C6997_RS19345	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C6997_RS19350	COG0589	response to stress
C6997_RS19380	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6997_RS19460	COG3547	Transposase (IS116 IS110 IS902 family)
C6997_RS19480	COG1030	water channel activity
C6997_RS19500	COG4220	transposase activity
C6997_RS19530	COG3772	lysozyme
C6997_RS19575	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C6997_RS19580	COG1403	HNH endonuclease
C6997_RS19635	COG1846	Transcriptional regulator
C6997_RS19640	COG1484	DNA-dependent DNA replication
C6997_RS19645	COG1846	Transcriptional regulator
C6997_RS19695	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6997_RS19705	COG0582	viral genome integration into host DNA
C6997_RS19715	COG1063	alcohol dehydrogenase
C6997_RS19720	COG4948	Mandelate Racemase Muconate Lactonizing
C6997_RS19740	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C6997_RS19760	COG0243	molybdopterin cofactor binding
C6997_RS19765	COG0437	4 iron, 4 sulfur cluster binding
C6997_RS19770	COG3302	dmso reductase anchor subunit
C6997_RS19775	COG3381	protein complex oligomerization
C6997_RS19785	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C6997_RS19790	COG1940	carbohydrate kinase activity
C6997_RS19795	COG0583	DNA-binding transcription factor activity
C6997_RS19800	COG2814	Major facilitator Superfamily
C6997_RS19820	COG3591	Belongs to the peptidase S1B family
C6997_RS19850	COG4626	Terminase
C6997_RS19850	COG1802	Transcriptional regulator
C6997_RS19965	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
C6997_RS19970	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
C6997_RS19985	COG0531	amino acid
C6997_RS20000	COG0745	RESPONSE REGULATOR receiver
C6997_RS20005	COG2205	protein histidine kinase activity
C6997_RS20015	COG0114	fumarate hydratase activity
C6997_RS20020	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C6997_RS20020	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C6997_RS20025	COG1482	cell wall glycoprotein biosynthetic process
C6997_RS20030	COG5339	Protein conserved in bacteria
C6997_RS20045	COG3250	beta-galactosidase activity
C6997_RS20050	COG1309	transcriptional regulator
C6997_RS20055	COG1028	Short-chain dehydrogenase reductase Sdr
C6997_RS20060	COG1609	Transcriptional regulator
C6997_RS20065	COG1263	PTS System
C6997_RS20065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6997_RS20070	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C6997_RS20080	COG0673	inositol 2-dehydrogenase activity
C6997_RS20125	COG4659	FMN binding
C6997_RS20135	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C6997_RS20145	COG3104	oligopeptide transport
C6997_RS20150	COG0625	glutathione transferase activity
C6997_RS20155	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
C6997_RS20170	COG3895	Periplasmic Protein
C6997_RS20180	COG3133	Outer membrane lipoprotein
C6997_RS20195	COG1566	PFAM secretion protein HlyD family protein
C6997_RS20200	COG1289	transmembrane transporter activity
C6997_RS20205	COG2032	superoxide dismutase activity
C6997_RS20210	COG4989	oxidoreductase activity
C6997_RS20215	COG3313	Fe-S protein
C6997_RS20220	COG1309	transcriptional regulator
C6997_RS20225	COG1902	pentaerythritol trinitrate reductase activity
C6997_RS20230	COG0346	lactoylglutathione lyase activity
C6997_RS20240	COG1201	RNA secondary structure unwinding
C6997_RS20245	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C6997_RS20250	COG0791	NLP P60 protein
C6997_RS20255	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C6997_RS20260	COG2814	Major facilitator Superfamily
C6997_RS20280	COG0583	DNA-binding transcription factor activity
C6997_RS20285	COG2814	Major facilitator Superfamily
C6997_RS20290	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C6997_RS20295	COG0307	riboflavin synthase, alpha
C6997_RS20305	COG3468	outer membrane autotransporter barrel domain protein
C6997_RS20325	COG4529	Protein conserved in bacteria
C6997_RS20335	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
C6997_RS20340	COG0437	4 iron, 4 sulfur cluster binding
C6997_RS20350	COG2414	aldehyde ferredoxin oxidoreductase
C6997_RS20355	COG0437	4 iron, 4 sulfur cluster binding
C6997_RS20365	COG0469	pyruvate kinase activity
C6997_RS20370	COG4238	major outer membrane lipoprotein
C6997_RS20375	COG1376	ErfK ybiS ycfS ynhG family protein
C6997_RS20390	COG0719	Fe-S assembly protein
C6997_RS20395	COG0396	ATPase activity
C6997_RS20400	COG0719	Fe-S assembly protein
C6997_RS20405	COG0316	Belongs to the HesB IscA family
C6997_RS20415	COG2050	protein possibly involved in aromatic compounds catabolism
C6997_RS20420	COG0277	FAD linked oxidase domain protein
C6997_RS20420	COG0247	lactate metabolic process
C6997_RS20430	COG0628	permease
C6997_RS20445	COG0738	Major facilitator superfamily
C6997_RS20450	COG2271	Major facilitator Superfamily
C6997_RS20470	COG1960	acyl-CoA dehydrogenase activity
C6997_RS20475	COG2207	Transcriptional regulator
C6997_RS20475	COG1917	Cupin 2, conserved barrel domain protein
C6997_RS20485	COG2086	electron transfer activity
C6997_RS20490	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C6997_RS20495	COG0644	oxidoreductase
C6997_RS20500	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C6997_RS20505	COG0318	PFAM AMP-dependent synthetase and ligase
C6997_RS20510	COG0574	Belongs to the PEP-utilizing enzyme family
C6997_RS20510	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C6997_RS20525	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C6997_RS20530	COG4256	Hemin uptake protein
C6997_RS20540	COG2200	EAL domain
C6997_RS20545	COG0791	NLP P60 protein
C6997_RS20555	COG0386	Belongs to the glutathione peroxidase family
C6997_RS20615	COG3137	Salt-induced outer membrane protein
C6997_RS20620	COG1105	Belongs to the carbohydrate kinase PfkB family
C6997_RS20630	COG3001	Fructosamine kinase
C6997_RS20640	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C6997_RS20645	COG1988	membrane-bound metal-dependent
C6997_RS20650	COG1823	symporter activity
C6997_RS20670	COG0753	catalase activity
C6997_RS20680	COG1486	melibiose metabolic process
C6997_RS20685	COG1917	Cupin 2, conserved barrel domain protein
C6997_RS20685	COG2169	Transcriptional regulator
C6997_RS20690	COG1447	Phosphotransferase system cellobiose-specific component IIA
C6997_RS20695	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C6997_RS20700	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C6997_RS20710	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C6997_RS20720	COG0322	excinuclease ABC activity
C6997_RS20730	COG3678	ATP-independent chaperone mediated protein folding
C6997_RS20765	COG0708	Exodeoxyribonuclease III
C6997_RS20770	COG0398	Pfam SNARE associated Golgi protein
C6997_RS20780	COG0398	Pfam SNARE associated Golgi protein
C6997_RS20785	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C6997_RS20790	COG4134	Bacterial extracellular solute-binding protein
C6997_RS20795	COG4135	transport system, permease component
C6997_RS20800	COG4136	ATPase activity
C6997_RS20805	COG2897	thiosulfate sulfurtransferase activity
C6997_RS20810	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C6997_RS20815	COG0494	nUDIX hydrolase
C6997_RS20825	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C6997_RS20835	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C6997_RS20850	COG0778	Nitroreductase
C6997_RS20860	COG0616	signal peptide processing
C6997_RS20865	COG0252	asparaginase activity
C6997_RS20870	COG1335	isochorismatase
C6997_RS20875	COG3139	Protein of unknown function (DUF1315)
C6997_RS20885	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C6997_RS20890	COG0676	glucose-6-phosphate 1-epimerase activity
C6997_RS20895	COG0656	L-ascorbic acid biosynthetic process
C6997_RS20900	COG3713	MltA-interacting MipA family protein
C6997_RS20905	COG2766	serine protein kinase
C6997_RS20915	COG2199	diguanylate cyclase activity
C6997_RS20920	COG2199	diguanylate cyclase activity
C6997_RS20925	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C6997_RS20940	COG2207	Transcriptional regulator
C6997_RS20945	COG2807	transmembrane transport
C6997_RS20950	COG3189	MarR family transcriptional regulator
C6997_RS20990	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C6997_RS21020	COG3299	homolog of phage Mu protein gp47
C6997_RS21030	COG4384	Bacteriophage Mu Gp45 protein
C6997_RS21050	COG4518	Phage tail assembly chaperone proteins, E, or 41 or 14
C6997_RS21085	COG4397	Mu-like prophage major head subunit gpT
C6997_RS21090	COG4388	Caudovirus prohead serine protease
C6997_RS21095	COG5005	Phage virion morphogenesis
C6997_RS21100	COG2369	cell adhesion
C6997_RS21105	COG4383	Mu-like prophage protein gp29
C6997_RS21110	COG4373	Mu-like prophage FluMu protein gp28
C6997_RS21145	COG5566	PFAM Mor transcription activator
C6997_RS21195	COG4396	Host-nuclease inhibitor protein Gam
C6997_RS21225	COG2842	Transposition protein
C6997_RS21250	COG2199	diguanylate cyclase activity
C6997_RS21250	COG2203	Gaf domain
C6997_RS21265	COG2261	transglycosylase associated protein
C6997_RS21270	COG0675	Transposase, IS605 OrfB family
C6997_RS21285	COG3615	Tellurite resistance protein tehB
C6997_RS21295	COG0583	DNA-binding transcription factor activity
C6997_RS21300	COG0473	3-isopropylmalate dehydrogenase activity
C6997_RS21305	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C6997_RS21310	COG4638	Rieske (2fe-2S)
C6997_RS21315	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C6997_RS21320	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
C6997_RS21325	COG0318	PFAM AMP-dependent synthetase and ligase
C6997_RS21330	COG3065	identical protein binding
C6997_RS21335	COG1214	PFAM Peptidase M22, glycoprotease
C6997_RS21340	COG1199	ATP-dependent helicase activity
C6997_RS21345	COG0251	oxidation-reduction process
C6997_RS21360	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C6997_RS21370	COG1760	l-serine dehydratase
C6997_RS21375	COG2200	EAL domain
C6997_RS21380	COG1253	flavin adenine dinucleotide binding
C6997_RS21395	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6997_RS21395	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6997_RS21400	COG3715	PTS system
C6997_RS21405	COG3716	PTS system mannose fructose sorbose family IID component
C6997_RS21425	COG2226	methyltransferase
C6997_RS21460	COG1414	Transcriptional regulator
C6997_RS21465	COG2814	Major facilitator Superfamily
C6997_RS21475	COG0793	Belongs to the peptidase S41A family
C6997_RS21485	COG1956	GAF domain-containing protein
C6997_RS21490	COG2995	paraquat-inducible protein a
C6997_RS21495	COG3008	intermembrane lipid transfer
C6997_RS21515	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C6997_RS21545	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6997_RS21560	COG2032	superoxide dismutase activity
C6997_RS21700	COG3772	lysozyme
C6997_RS21735	COG3436	PFAM IS66 Orf2 family protein
C6997_RS21740	COG4372	Transposase
C6997_RS21770	COG2207	Transcriptional regulator
C6997_RS21820	COG1196	nuclear chromosome segregation
C6997_RS21835	COG1846	Transcriptional regulator
C6997_RS21840	COG1484	DNA-dependent DNA replication
C6997_RS21845	COG3756	Protein conserved in bacteria
C6997_RS21885	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6997_RS21890	COG3723	Recombinational DNA repair protein, rece pathway
C6997_RS21910	COG0582	viral genome integration into host DNA
C6997_RS21920	COG1276	copper resistance
C6997_RS21925	COG2372	response to copper ion
C6997_RS21935	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C6997_RS21940	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6997_RS21945	COG1770	oligopeptidase
C6997_RS21950	COG2979	Protein of unknown function (DUF533)
C6997_RS21960	COG3141	response to X-ray
C6997_RS21970	COG0800	Aldolase
C6997_RS21975	COG0129	dihydroxy-acid dehydratase activity
C6997_RS21980	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C6997_RS21985	COG1737	Transcriptional regulator
C6997_RS21990	COG0469	pyruvate kinase activity
C6997_RS22015	COG3833	ABC-type maltose transport systems, permease component
C6997_RS22020	COG1175	transmembrane transport
C6997_RS22025	COG2182	Extracellular solute-binding protein
C6997_RS22035	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C6997_RS22045	COG3842	ATPase activity
C6997_RS22065	COG1560	Kdo2-lipid A biosynthetic process
C6997_RS22070	COG0739	heme binding
C6997_RS22075	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
C6997_RS22085	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C6997_RS22115	COG0217	transcriptional regulatory protein
C6997_RS22120	COG0494	nUDIX hydrolase
C6997_RS22130	COG1335	isochorismatase
C6997_RS22135	COG1801	Protein of unknown function DUF72
C6997_RS22140	COG3788	relative of glutathione S-transferase, MAPEG superfamily
C6997_RS22155	COG0243	molybdopterin cofactor binding
C6997_RS22160	COG3005	denitrification pathway
C6997_RS22170	COG3102	Protein conserved in bacteria
C6997_RS22185	COG3755	Protein conserved in bacteria
C6997_RS22195	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C6997_RS22200	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C6997_RS22205	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
C6997_RS22210	COG0745	RESPONSE REGULATOR receiver
C6997_RS22215	COG2201	protein-glutamate methylesterase activity
C6997_RS22220	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C6997_RS22225	COG0840	transmembrane signaling receptor activity
C6997_RS22230	COG0840	transmembrane signaling receptor activity
C6997_RS22235	COG0835	chemotaxis
C6997_RS22240	COG2198	Histidine kinase
C6997_RS22240	COG0643	Histidine kinase
C6997_RS22245	COG1360	Flagellar Motor Protein
C6997_RS22250	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C6997_RS22265	COG0589	response to stress
C6997_RS22275	COG1877	trehalose-phosphatase activity
C6997_RS22280	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6997_RS22285	COG1129	ABC transporter
C6997_RS22290	COG1879	ABC-type sugar transport system periplasmic component
C6997_RS22300	COG1528	Iron-storage protein
C6997_RS22320	COG1528	Iron-storage protein
C6997_RS22330	COG0814	amino acid
C6997_RS22335	COG3318	Belongs to the UPF0149 family
C6997_RS22335	COG3012	SEC-C Motif Domain Protein
C6997_RS22340	COG4974	Belongs to the 'phage' integrase family
C6997_RS22420	COG4695	Portal protein
C6997_RS22505	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6997_RS22510	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C6997_RS22600	COG2197	response regulator
C6997_RS22615	COG2197	response regulator
C6997_RS22620	COG1126	abc transporter atp-binding protein
C6997_RS22625	COG0765	amino acid transport
C6997_RS22635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6997_RS22645	COG1191	sigma factor activity
C6997_RS22660	COG1516	flagellar protein fliS
C6997_RS22670	COG0366	Alpha amylase catalytic
C6997_RS22685	COG2391	methyltransferase activity
C6997_RS22690	COG0425	Belongs to the sulfur carrier protein TusA family
C6997_RS22695	COG2135	peptidase activity
C6997_RS22710	COG1766	The M ring may be actively involved in energy transduction
C6997_RS22715	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C6997_RS22720	COG1317	bacterial-type flagellum organization
C6997_RS22725	COG1157	protein secretion by the type III secretion system
C6997_RS22730	COG2882	bacterial-type flagellum organization
C6997_RS22735	COG3144	bacterial-type flagellum assembly
C6997_RS22740	COG1580	Controls the rotational direction of flagella during chemotaxis
C6997_RS22745	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C6997_RS22750	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C6997_RS22755	COG3190	flagellar
C6997_RS22760	COG1338	Plays a role in the flagellum-specific transport system
C6997_RS22765	COG1987	bacterial-type flagellum assembly
C6997_RS22770	COG1684	flagellar biosynthetic protein fliR
C6997_RS22775	COG2197	response regulator
C6997_RS22810	COG5475	Uncharacterized small protein (DUF2158)
C6997_RS22815	COG2354	Protein conserved in bacteria
C6997_RS22820	COG0697	spore germination
C6997_RS22825	COG3727	T/G mismatch-specific endonuclease activity
C6997_RS22830	COG0270	DNA (cytosine-5-)-methyltransferase activity
C6997_RS22850	COG2205	protein histidine kinase activity
C6997_RS22855	COG0745	RESPONSE REGULATOR receiver
C6997_RS22860	COG2351	hydroxyisourate hydrolase activity
C6997_RS22875	COG3443	Belongs to the bacterial solute-binding protein 9 family
C6997_RS22905	COG1169	isochorismate synthase
C6997_RS22910	COG2814	Major facilitator Superfamily
C6997_RS22915	COG1132	(ABC) transporter
C6997_RS22930	COG2226	methyltransferase
C6997_RS22930	COG3433	isochorismatase activity
C6997_RS22930	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C6997_RS22950	COG1021	2,3-dihydroxybenzoate-AMP ligase
C6997_RS22955	COG4771	TonB-dependent receptor
C6997_RS22960	COG2373	Large extracellular alpha-helical protein
C6997_RS22960	COG1388	LysM domain
C6997_RS22960	COG4932	domain protein
C6997_RS22965	COG1470	cell adhesion involved in biofilm formation
C6997_RS22965	COG1388	LysM domain
C6997_RS22970	COG1388	LysM domain
C6997_RS22970	COG1470	cell adhesion involved in biofilm formation
C6997_RS22975	COG1388	LysM domain
C6997_RS22975	COG1470	cell adhesion involved in biofilm formation
C6997_RS22985	COG0477	Major facilitator Superfamily
C6997_RS22990	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C6997_RS22995	COG0217	transcriptional regulatory protein
C6997_RS23010	COG0534	Mate efflux family protein
C6997_RS23025	COG0583	DNA-binding transcription factor activity
C6997_RS23035	COG1376	ErfK ybiS ycfS ynhG family protein
C6997_RS23050	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
C6997_RS23070	COG1735	metal-dependent hydrolase with the TIM-barrel fold
C6997_RS23185	COG3436	PFAM IS66 Orf2 family protein
C6997_RS23190	COG4372	Transposase
C6997_RS23240	COG2003	Belongs to the UPF0758 family
C6997_RS23285	COG1289	transmembrane transporter activity
C6997_RS23300	COG2925	Exonuclease
C6997_RS23305	COG0425	Belongs to the sulfur carrier protein TusA family
C6997_RS23310	COG2391	methyltransferase activity
C6997_RS23315	COG0531	amino acid
C6997_RS23325	COG0583	DNA-binding transcription factor activity
C6997_RS23330	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C6997_RS23335	COG4115	mRNA cleavage
C6997_RS23340	COG2161	toxin-antitoxin pair type II binding
C6997_RS23370	COG0131	Imidazoleglycerol-phosphate dehydratase
C6997_RS23370	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C6997_RS23375	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C6997_RS23405	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C6997_RS23410	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C6997_RS23415	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C6997_RS23425	COG0297	glycogen (starch) synthase activity
C6997_RS23435	COG1216	Glycosyl transferase, family 2
C6997_RS23465	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C6997_RS23470	COG1088	dTDP-glucose 4,6-dehydratase activity
C6997_RS23480	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C6997_RS23490	COG0438	transferase activity, transferring glycosyl groups
C6997_RS23495	COG2327	Polysaccharide pyruvyl transferase
C6997_RS23500	COG2244	polysaccharide biosynthetic process
C6997_RS23505	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C6997_RS23510	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C6997_RS23515	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
C6997_RS23515	COG0662	Cupin 2, conserved barrel domain protein
C6997_RS23520	COG0297	glycogen (starch) synthase activity
C6997_RS23525	COG1051	belongs to the nudix hydrolase family
C6997_RS23530	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C6997_RS23535	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
C6997_RS23540	COG0110	maltose O-acetyltransferase activity
C6997_RS23545	COG1216	Glycosyl transferase, family 2
C6997_RS23555	COG0438	transferase activity, transferring glycosyl groups
C6997_RS23560	COG1045	serine acetyltransferase
C6997_RS23565	COG0463	Glycosyl transferase, family 2
C6997_RS23570	COG3206	protein involved in exopolysaccharide biosynthesis
C6997_RS23570	COG0489	protein tyrosine kinase activity
C6997_RS23575	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C6997_RS23580	COG1596	polysaccharide export
C6997_RS23585	COG1253	flavin adenine dinucleotide binding
C6997_RS23595	COG2982	Protein involved in outer membrane biogenesis
C6997_RS23605	COG0572	uridine kinase
C6997_RS23610	COG3447	MASE1 domain protein
C6997_RS23610	COG5001	Diguanylate cyclase
C6997_RS23610	COG5002	protein histidine kinase activity
C6997_RS23615	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C6997_RS23620	COG0443	Heat shock 70 kDa protein
C6997_RS23625	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
C6997_RS23630	COG0631	protein serine/threonine phosphatase activity
C6997_RS23635	COG4245	von Willebrand factor, type A
C6997_RS23675	COG2205	protein histidine kinase activity
C6997_RS23680	COG0745	RESPONSE REGULATOR receiver
C6997_RS23690	COG3609	addiction module antidote protein, CC2985 family
C6997_RS23700	COG0826	peptidase U32
C6997_RS23730	COG3775	system Galactitol-specific IIC component
C6997_RS23735	COG3414	Phosphotransferase system galactitol-specific IIB component
C6997_RS23740	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6997_RS23755	COG1830	Aldolase
C6997_RS23760	COG2211	Major facilitator Superfamily
C6997_RS23765	COG1397	ADP-ribosylglycohydrolase
C6997_RS23770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6997_RS23775	COG2188	Transcriptional regulator
C6997_RS23780	COG3757	hydrolase, family 25
C6997_RS23785	COG0351	phosphomethylpyrimidine kinase
C6997_RS23800	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
C6997_RS23805	COG5455	response to cobalt ion
C6997_RS23810	COG3539	Fimbrial protein
C6997_RS23815	COG3188	usher protein
C6997_RS23820	COG3121	Chaperone
C6997_RS23825	COG3539	Fimbrial protein
C6997_RS23840	COG0489	protein tyrosine kinase activity
C6997_RS23855	COG3831	ATPase activity
C6997_RS23865	COG0714	Associated with various cellular activities
C6997_RS23870	COG2425	protein containing a von Willebrand factor type A (vWA) domain
C6997_RS23875	COG3552	Protein containing von Willebrand factor type A (VWA) domain
C6997_RS23880	COG4715	Zinc finger, swim domain protein
C6997_RS23890	COG3436	PFAM IS66 Orf2 family protein
C6997_RS23895	COG4372	Transposase
C6997_RS23905	COG4807	Protein conserved in bacteria
C6997_RS23910	COG3279	Response regulator of the LytR AlgR family
C6997_RS23915	COG3275	phosphorelay sensor kinase activity
C6997_RS23920	COG0789	Transcriptional regulator
C6997_RS23930	COG1174	glycine betaine transport
C6997_RS23935	COG1125	glycine betaine transport
C6997_RS23940	COG1174	glycine betaine transport
C6997_RS23945	COG1732	Glycine betaine
C6997_RS23950	COG1472	Belongs to the glycosyl hydrolase 3 family
C6997_RS23955	COG0277	FAD linked oxidase domain protein
C6997_RS23960	COG1686	Belongs to the peptidase S11 family
C6997_RS23970	COG0586	Pfam SNARE associated Golgi protein
C6997_RS23975	COG1028	Short-chain dehydrogenase reductase Sdr
C6997_RS24000	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C6997_RS24010	COG1346	cytolysis
C6997_RS24020	COG2949	membrane
C6997_RS24030	COG0493	'glutamate synthase
C6997_RS24035	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
C6997_RS24035	COG0167	dihydroorotate dehydrogenase activity
C6997_RS24040	COG4211	Belongs to the binding-protein-dependent transport system permease family
C6997_RS24045	COG1129	ABC transporter
C6997_RS24050	COG1879	ABC-type sugar transport system periplasmic component
C6997_RS24055	COG1609	Transcriptional regulator
C6997_RS24065	COG2311	Membrane
C6997_RS24090	COG4771	TonB-dependent receptor
C6997_RS24100	COG0833	amino acid
C6997_RS24110	COG0583	DNA-binding transcription factor activity
C6997_RS24115	COG2855	membrane
C6997_RS24125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6997_RS24125	COG1522	sequence-specific DNA binding
C6997_RS24130	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C6997_RS24140	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C6997_RS24145	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C6997_RS24150	COG2313	pseudouridylate synthase activity
C6997_RS24155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6997_RS24160	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
C6997_RS24160	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6997_RS24160	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6997_RS24165	COG1105	Belongs to the carbohydrate kinase PfkB family
C6997_RS24170	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6997_RS24170	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6997_RS24175	COG2814	Major facilitator Superfamily
C6997_RS24190	COG0246	Mannitol dehydrogenase
C6997_RS24195	COG0523	cobalamin synthesis protein
C6997_RS24200	COG0671	phosphoesterase, PA-phosphatase related
C6997_RS24205	COG0791	NLP P60 protein
C6997_RS24210	COG2200	EAL domain
C6997_RS24215	COG4166	transmembrane transport
C6997_RS24220	COG4174	ABC transporter (Permease)
C6997_RS24225	COG4239	(ABC) transporter, permease
C6997_RS24230	COG4172	Belongs to the ABC transporter superfamily
C6997_RS24245	COG2814	Major facilitator Superfamily
C6997_RS24250	COG1187	pseudouridine synthase activity
C6997_RS24260	COG1061	Type III restriction enzyme res subunit
C6997_RS24280	COG3083	sulfuric ester hydrolase activity
C6997_RS24290	COG0582	viral genome integration into host DNA
C6997_RS24380	COG2197	response regulator
C6997_RS24385	COG3088	subunit of a heme lyase
C6997_RS24385	COG4235	cytochrome complex assembly
C6997_RS24390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C6997_RS24395	COG1138	Cytochrome C-type biogenesis protein
C6997_RS24405	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C6997_RS24410	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C6997_RS24415	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C6997_RS24420	COG4133	protoheme IX ABC transporter activity
C6997_RS24425	COG3005	denitrification pathway
C6997_RS24430	COG3043	anaerobic respiration
C6997_RS24435	COG0348	domain, Protein
C6997_RS24440	COG0437	4 iron, 4 sulfur cluster binding
C6997_RS24450	COG3062	negative regulation of establishment of protein localization
C6997_RS24455	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6997_RS24455	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6997_RS24475	COG4615	Cyclic peptide transporter
C6997_RS24480	COG3145	DNA-N1-methyladenine dioxygenase activity
C6997_RS24485	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C6997_RS24485	COG2169	Transcriptional regulator
C6997_RS24490	COG1477	protein flavinylation
C6997_RS24495	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C6997_RS24510	COG0642	Histidine kinase
C6997_RS24510	COG2198	Histidine kinase
C6997_RS24515	COG2197	response regulator
C6997_RS24520	COG0784	Response regulator, receiver
C6997_RS24520	COG2205	protein histidine kinase activity
C6997_RS24525	COG4676	Protein conserved in bacteria
C6997_RS24530	COG5445	Predicted secreted protein (DUF2300)
C6997_RS24535	COG2373	Large extracellular alpha-helical protein
C6997_RS24570	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6997_RS24585	COG4372	Transposase
C6997_RS24590	COG3436	PFAM IS66 Orf2 family protein
C6997_RS24695	COG4220	transposase activity
C6997_RS24715	COG3772	lysozyme
C6997_RS24915	COG0582	viral genome integration into host DNA
C6997_RS24920	COG3234	Protein of unknown function (DUF1175)
C6997_RS24925	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
C6997_RS24930	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C6997_RS24940	COG3468	outer membrane autotransporter barrel domain protein
C6997_RS24950	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C6997_RS24955	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C6997_RS24960	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C6997_RS24965	COG3642	lipopolysaccharide core region biosynthetic process
C6997_RS24970	COG0583	DNA-binding transcription factor activity
C6997_RS24975	COG0584	glycerophosphoryl diester phosphodiesterase
C6997_RS24980	COG2271	Major facilitator Superfamily
C6997_RS24985	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C6997_RS24995	COG0247	lactate metabolic process
C6997_RS25000	COG5464	transposase or invertase
C6997_RS25070	COG0318	PFAM AMP-dependent synthetase and ligase
C6997_RS25080	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C6997_RS25095	COG1169	isochorismate synthase
C6997_RS25100	COG4575	ribosome binding
C6997_RS25105	COG2153	protein acetylation
C6997_RS25120	COG2304	oxidoreductase activity
C6997_RS25125	COG2234	aminopeptidase activity
C6997_RS25140	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C6997_RS25145	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C6997_RS25155	COG0839	Belongs to the complex I subunit 6 family
C6997_RS25170	COG1034	ATP synthesis coupled electron transport
C6997_RS25175	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
C6997_RS25180	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
C6997_RS25200	COG0583	DNA-binding transcription factor activity
C6997_RS25210	COG0436	Aminotransferase
C6997_RS25220	COG0490	domain, Protein
C6997_RS25220	COG0471	metal ion transport
C6997_RS25225	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C6997_RS25240	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C6997_RS25245	COG0280	phosphate acetyltransferase
C6997_RS25245	COG0857	belongs to the CobB CobQ family
C6997_RS25250	COG1288	antiporter activity
C6997_RS25255	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
C6997_RS25260	COG0622	Phosphoesterase
C6997_RS25265	COG0625	glutathione transferase activity
C6997_RS25270	COG0625	glutathione transferase activity
C6997_RS25275	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C6997_RS25280	COG1090	epimerase
C6997_RS25285	COG5464	transposase or invertase
C6997_RS25290	COG4598	ABC transporter
C6997_RS25295	COG4160	amino acid transport
C6997_RS25300	COG4215	(ABC) transporter
C6997_RS25305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6997_RS25310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6997_RS25315	COG0163	prenyltransferase activity
C6997_RS25320	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C6997_RS25325	COG1286	toxin biosynthetic process
C6997_RS25330	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
C6997_RS25335	COG0285	dihydrofolate synthase activity
C6997_RS25345	COG0586	Pfam SNARE associated Golgi protein
C6997_RS25355	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C6997_RS25370	COG2814	Major facilitator Superfamily
C6997_RS25380	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C6997_RS25395	COG3101	peptidyl-lysine hydroxylation
C6997_RS25400	COG0730	response to heat
C6997_RS25435	COG3539	Fimbrial protein
C6997_RS25440	COG3539	Fimbrial protein
C6997_RS25445	COG3121	Chaperone
C6997_RS25450	COG3188	usher protein
C6997_RS25455	COG3539	Fimbrial protein
C6997_RS25460	COG2062	phosphohistidine phosphatase, SixA
C6997_RS25475	COG3691	Protein conserved in bacteria
C6997_RS25485	COG2067	long-chain fatty acid transport protein
C6997_RS25500	COG2853	Lipoprotein
C6997_RS25510	COG2116	formate transmembrane transporter activity
C6997_RS25550	COG3436	PFAM IS66 Orf2 family protein
C6997_RS25555	COG4372	Transposase
C6997_RS25610	COG3468	outer membrane autotransporter barrel domain protein
C6997_RS25630	COG2003	Belongs to the UPF0758 family
C6997_RS25675	COG0477	Major facilitator Superfamily
C6997_RS25680	COG1566	PFAM secretion protein HlyD family protein
C6997_RS25685	COG2197	response regulator
C6997_RS25690	COG2205	protein histidine kinase activity
C6997_RS25690	COG0784	Response regulator, receiver
C6997_RS25690	COG2198	Histidine kinase
C6997_RS25690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6997_RS25695	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C6997_RS25700	COG0679	Auxin Efflux Carrier
C6997_RS25705	COG0028	Belongs to the TPP enzyme family
C6997_RS25735	COG1560	Kdo2-lipid A biosynthetic process
C6997_RS25745	COG0436	Aminotransferase
C6997_RS25750	COG3275	phosphorelay sensor kinase activity
C6997_RS25755	COG3279	Response regulator of the LytR AlgR family
C6997_RS25760	COG2207	Transcriptional regulator
C6997_RS25770	COG1363	Peptidase, m42
C6997_RS25775	COG0006	proline dipeptidase activity
C6997_RS25780	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6997_RS25785	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6997_RS25810	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C6997_RS25815	COG2200	EAL domain
C6997_RS25815	COG2199	diguanylate cyclase activity
C6997_RS25830	COG3415	Transposase
C6997_RS25835	COG3415	Transposase
C6997_RS25870	COG0583	DNA-binding transcription factor activity
C6997_RS25880	COG2211	Major facilitator Superfamily
C6997_RS25885	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
C6997_RS25895	COG0583	DNA-binding transcription factor activity
C6997_RS25900	COG0385	Bile acid
C6997_RS25905	COG3530	Putative quorum-sensing-regulated virulence factor
C6997_RS25925	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C6997_RS25930	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6997_RS25935	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C6997_RS25940	COG2190	(PTS) system
C6997_RS25955	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C6997_RS25960	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C6997_RS25965	COG4208	sulfate ABC transporter
C6997_RS25970	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
C6997_RS25975	COG4150	thiosulfate binding
C6997_RS25980	COG1028	Short-chain dehydrogenase reductase Sdr
C6997_RS25995	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6997_RS25995	COG1263	PTS System
C6997_RS26000	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C6997_RS26005	COG2837	iron assimilation
C6997_RS26025	COG0860	N-Acetylmuramoyl-L-alanine amidase
C6997_RS26035	COG2207	Transcriptional regulator
C6997_RS26040	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
C6997_RS26045	COG4816	utilization protein
C6997_RS26055	COG4303	Ethanolamine ammonia lyase large subunit
C6997_RS26060	COG4819	ethanolamine utilization protein
C6997_RS26065	COG3192	ethanolamine utilization protein
C6997_RS26070	COG1454	alcohol dehydrogenase
C6997_RS26075	COG4820	ethanolamine utilization protein (EutJ)
C6997_RS26080	COG1012	belongs to the aldehyde dehydrogenase family
C6997_RS26085	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
C6997_RS26090	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
C6997_RS26095	COG0280	phosphate acetyltransferase
C6997_RS26100	COG4812	Cobalamin adenosyltransferase
C6997_RS26105	COG4766	ethanolamine catabolic process
C6997_RS26110	COG4917	ethanolamine utilization protein
C6997_RS26115	COG4810	utilization protein
C6997_RS26125	COG0280	phosphate acetyltransferase
C6997_RS26125	COG0281	malic enzyme
C6997_RS26130	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C6997_RS26135	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C6997_RS26140	COG5342	invasion associated locus B
C6997_RS26150	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6997_RS26150	COG0493	'glutamate synthase
C6997_RS26155	COG3850	Histidine kinase
C6997_RS26160	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C6997_RS26175	COG1393	Belongs to the ArsC family
C6997_RS26190	COG0400	carboxylic ester hydrolase activity
C6997_RS26200	COG2321	neutral zinc metallopeptidase
C6997_RS26220	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
C6997_RS26230	COG2716	regulation of RNA biosynthetic process
C6997_RS26235	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C6997_RS26240	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6997_RS26245	COG0651	ATP synthesis coupled electron transport
C6997_RS26250	COG0650	Formate hydrogenlyase subunit 4
C6997_RS26255	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C6997_RS26260	COG4237	Hydrogenase 4 membrane
C6997_RS26265	COG0651	ATP synthesis coupled electron transport
C6997_RS26270	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
C6997_RS26270	COG3261	NADH dehydrogenase
C6997_RS26275	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C6997_RS26290	COG3604	Transcriptional regulator
C6997_RS26295	COG2116	formate transmembrane transporter activity
C6997_RS26305	COG0628	permease
C6997_RS26310	COG4783	chaperone-mediated protein folding
C6997_RS26315	COG1393	Belongs to the ArsC family
C6997_RS26325	COG2233	PERMEase
C6997_RS26345	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C6997_RS26350	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
C6997_RS26355	COG0248	Ppx GppA phosphatase
C6997_RS26360	COG2200	EAL domain
C6997_RS26380	COG3133	Outer membrane lipoprotein
C6997_RS26395	COG0516	GMP reductase activity
C6997_RS26395	COG0517	IMP dehydrogenase activity
C6997_RS26405	COG1645	bacterial-type flagellum-dependent swarming motility
C6997_RS26420	COG2976	Protein conserved in bacteria
C6997_RS26455	COG4953	penicillin-binding protein 1C
C6997_RS26460	COG2373	Large extracellular alpha-helical protein
C6997_RS26465	COG2897	thiosulfate sulfurtransferase activity
C6997_RS26480	COG2975	iron-sulfur cluster assembly
C6997_RS26485	COG0633	Ferredoxin
C6997_RS26505	COG0822	iron-sulfur transferase activity
C6997_RS26525	COG0483	inositol monophosphate 1-phosphatase activity
C6997_RS26530	COG1073	alpha beta
C6997_RS26535	COG3711	transcriptional antiterminator
C6997_RS26540	COG2814	Major facilitator Superfamily
C6997_RS26545	COG0583	DNA-binding transcription factor activity
C6997_RS26550	COG4638	Rieske (2fe-2S)
C6997_RS26575	COG2259	Doxx family
C6997_RS26580	COG2017	converts alpha-aldose to the beta-anomer
C6997_RS26585	COG1063	alcohol dehydrogenase
C6997_RS26590	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6997_RS26595	COG1129	ABC transporter
C6997_RS26600	COG1879	ABC-type sugar transport system periplasmic component
C6997_RS26605	COG0457	Tetratricopeptide repeat
C6997_RS26610	COG1940	carbohydrate kinase activity
C6997_RS26620	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C6997_RS26620	COG1017	nitric oxide dioxygenase activity
C6997_RS26625	COG0347	Belongs to the P(II) protein family
C6997_RS26630	COG2204	response regulator
C6997_RS26635	COG3170	Tfp pilus assembly protein FimV
C6997_RS26640	COG2205	protein histidine kinase activity
C6997_RS26645	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C6997_RS26645	COG0047	phosphoribosylformylglycinamidine synthase activity
C6997_RS26665	COG0560	Phosphoserine phosphatase
C6997_RS26670	COG1737	Transcriptional regulator
C6997_RS26675	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6997_RS26700	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
C6997_RS26725	COG0681	Belongs to the peptidase S26 family
C6997_RS26735	COG3086	response to oxidative stress
C6997_RS26740	COG3026	antisigma factor binding
C6997_RS26745	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
C6997_RS26750	COG1595	DNA-templated transcription, initiation
C6997_RS26755	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C6997_RS26765	COG0513	Belongs to the DEAD box helicase family
C6997_RS26770	COG0583	DNA-binding transcription factor activity
C6997_RS26790	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C6997_RS26800	COG3118	belongs to the thioredoxin family
C6997_RS26805	COG3148	PFAM DTW domain containing protein
C6997_RS26810	COG0045	succinate-CoA ligase (ADP-forming) activity
C6997_RS26810	COG1042	CoA-binding domain protein
C6997_RS26810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C6997_RS26815	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C6997_RS26820	COG5544	Lipoprotein
C6997_RS26825	COG0477	Major facilitator Superfamily
C6997_RS26855	COG0542	response to heat
C6997_RS26860	COG1496	oxidoreductase activity
C6997_RS26865	COG0564	pseudouridine synthase activity
C6997_RS26870	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C6997_RS26880	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C6997_RS26890	COG1605	Chorismate mutase
C6997_RS26890	COG0077	Prephenate dehydratase
C6997_RS26895	COG1605	Chorismate mutase
C6997_RS26895	COG0287	Prephenate dehydrogenase
C6997_RS26900	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C6997_RS26915	COG2199	diguanylate cyclase activity
C6997_RS26920	COG2885	chlorophyll binding
C6997_RS26945	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C6997_RS26950	COG4137	Cytochrome C assembly protein
C6997_RS26955	COG4536	flavin adenine dinucleotide binding
C6997_RS26975	COG0497	DNA recombination
C6997_RS26980	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C6997_RS26990	COG2867	negative regulation of translational initiation
C6997_RS27035	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6997_RS27155	COG3772	lysozyme
C6997_RS27215	COG1403	HNH endonuclease
C6997_RS27225	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C6997_RS27235	COG4725	Belongs to the MT-A70-like family
C6997_RS27245	COG1846	Transcriptional regulator
C6997_RS27265	COG4197	protein conserved in bacteria, prophage-related
C6997_RS27270	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C6997_RS27290	COG5532	Uncharacterized conserved protein (DUF2303)
C6997_RS27295	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
C6997_RS27340	COG0582	viral genome integration into host DNA
C6997_RS27350	COG0582	viral genome integration into host DNA
C6997_RS27385	COG0579	oxidoreductase
C6997_RS27390	COG1012	belongs to the aldehyde dehydrogenase family
C6997_RS27395	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C6997_RS27400	COG1113	amino acid transport
C6997_RS27405	COG1802	Transcriptional regulator
C6997_RS27410	COG1652	LysM domain
C6997_RS27415	COG0401	homolog of Blt101
C6997_RS27420	COG0640	Transcriptional regulator
C6997_RS27425	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C6997_RS27430	COG2916	Histone family protein nucleoid-structuring protein H-NS
C6997_RS27445	COG4575	ribosome binding
C6997_RS27450	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C6997_RS27460	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C6997_RS27465	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C6997_RS27470	COG4175	Glycine betaine
C6997_RS27475	COG4176	ABC-type proline glycine betaine transport system permease component
C6997_RS27480	COG2113	Glycine betaine
C6997_RS27485	COG2814	Major facilitator Superfamily
C6997_RS27490	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
C6997_RS27500	COG1846	Transcriptional regulator
C6997_RS27505	COG1566	PFAM secretion protein HlyD family protein
C6997_RS27510	COG2814	Major facilitator Superfamily
C6997_RS27525	COG1238	metal cluster binding
C6997_RS27530	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C6997_RS27555	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
C6997_RS27575	COG1546	Belongs to the CinA family
C6997_RS27580	COG2951	lytic endotransglycosylase activity
C6997_RS27585	COG3730	PTS system glucitol sorbitol-specific
C6997_RS27590	COG3732	PTS system glucitol sorbitol-specific
C6997_RS27600	COG1028	Short-chain dehydrogenase reductase Sdr
C6997_RS27605	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6997_RS27610	COG1349	DNA-binding transcription factor activity
C6997_RS27635	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
C6997_RS27640	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6997_RS27645	COG1609	Transcriptional regulator
C6997_RS27650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6997_RS27650	COG1263	PTS System
C6997_RS27655	COG2723	6-phospho-beta-galactosidase activity
C6997_RS27660	COG5499	transcription regulator containing HTH domain
C6997_RS27665	COG4680	protein conserved in bacteria
C6997_RS27675	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C6997_RS27685	COG3260	NADH ubiquinone oxidoreductase 20
C6997_RS27690	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C6997_RS27695	COG3261	NADH dehydrogenase
C6997_RS27695	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
C6997_RS27700	COG0650	Formate hydrogenlyase subunit 4
C6997_RS27705	COG0651	ATP synthesis coupled electron transport
C6997_RS27710	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6997_RS27720	COG0375	protein maturation
C6997_RS27725	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
C6997_RS27730	COG0298	carbon dioxide binding
C6997_RS27735	COG0409	Hydrogenase expression formation protein
C6997_RS27740	COG0309	Hydrogenase expression formation protein (HypE)
C6997_RS27745	COG3604	Transcriptional regulator
C6997_RS27760	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C6997_RS27765	COG1349	DNA-binding transcription factor activity
C6997_RS27770	COG2084	Dehydrogenase
C6997_RS27775	COG3395	kinase activity
C6997_RS27780	COG0235	Class ii aldolase
C6997_RS27785	COG3622	Belongs to the hyi family
C6997_RS27790	COG2610	gluconate transmembrane transporter activity
C6997_RS27800	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C6997_RS27815	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C6997_RS27820	COG4942	peptidase
C6997_RS27820	COG1388	LysM domain
C6997_RS27875	COG2234	aminopeptidase activity
C6997_RS27880	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6997_RS27885	COG1518	maintenance of DNA repeat elements
C6997_RS27900	COG1857	crispr-associated protein
C6997_RS27915	COG1203	CRISPR-associated helicase, Cas3
C6997_RS27945	COG0720	synthase
C6997_RS27950	COG0644	oxidoreductase
C6997_RS27955	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C6997_RS27960	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
C6997_RS27965	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C6997_RS27970	COG2086	electron transfer activity
C6997_RS27975	COG0477	Major facilitator Superfamily
C6997_RS27980	COG0277	FAD linked oxidase domain protein
C6997_RS27985	COG1028	Short-chain dehydrogenase reductase Sdr
C6997_RS27990	COG1028	Short-chain dehydrogenase reductase Sdr
C6997_RS27995	COG2223	nitrite transmembrane transporter activity
C6997_RS28000	COG1070	Carbohydrate kinase
C6997_RS28005	COG0602	queuosine metabolic process
C6997_RS28015	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
C6997_RS28030	COG3956	TIGRFAM MazG family protein
C6997_RS28035	COG2337	Toxic component of a toxin-antitoxin (TA) module
C6997_RS28040	COG2336	PFAM SpoVT AbrB
C6997_RS28045	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C6997_RS28055	COG3437	response regulator, receiver
C6997_RS28055	COG3850	Histidine kinase
C6997_RS28055	COG4999	Histidine kinase
C6997_RS28055	COG2205	protein histidine kinase activity
C6997_RS28060	COG4948	Mandelate Racemase Muconate Lactonizing
C6997_RS28065	COG4948	Mandelate Racemase Muconate Lactonizing
C6997_RS28070	COG2271	Major facilitator Superfamily
C6997_RS28075	COG0716	FMN binding
C6997_RS28080	COG0564	pseudouridine synthase activity
C6997_RS28085	COG3098	single-species biofilm formation
C6997_RS28100	COG1611	Belongs to the LOG family
C6997_RS28105	COG0814	amino acid
C6997_RS28110	COG1760	l-serine dehydratase
C6997_RS28120	COG1454	alcohol dehydrogenase
C6997_RS28125	COG0235	Class ii aldolase
C6997_RS28130	COG0738	Major facilitator superfamily
C6997_RS28140	COG1070	Carbohydrate kinase
C6997_RS28150	COG1349	DNA-binding transcription factor activity
C6997_RS28160	COG2363	Small membrane protein
C6997_RS28165	COG0583	DNA-binding transcription factor activity
C6997_RS28175	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C6997_RS28180	COG2166	iron-sulfur cluster assembly
C6997_RS28185	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C6997_RS28190	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
C6997_RS28225	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C6997_RS28230	COG1263	PTS System
C6997_RS28230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6997_RS28235	COG3711	transcriptional antiterminator
C6997_RS28240	COG0860	N-Acetylmuramoyl-L-alanine amidase
C6997_RS28250	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C6997_RS28250	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C6997_RS28255	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C6997_RS28260	COG1074	ATP-dependent DNA helicase activity
C6997_RS28265	COG1025	Belongs to the peptidase M16 family
C6997_RS28270	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
C6997_RS28275	COG4967	type IV pilus modification protein PilV
C6997_RS28285	COG4795	General secretion pathway protein
C6997_RS28290	COG2165	general secretion pathway protein
C6997_RS28305	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
C6997_RS28320	COG0861	Integral membrane protein TerC family
C6997_RS28330	COG0667	Aldo Keto reductase
C6997_RS28345	COG1609	Transcriptional regulator
C6997_RS28355	COG0583	DNA-binding transcription factor activity
C6997_RS28360	COG1794	racemase activity, acting on amino acids and derivatives
C6997_RS28365	COG2814	Major facilitator Superfamily
C6997_RS28370	COG1028	Short-chain dehydrogenase reductase Sdr
C6997_RS28380	COG0183	Belongs to the thiolase family
C6997_RS28385	COG0814	amino acid
C6997_RS28390	COG2771	luxR family
C6997_RS28395	COG3710	Transcriptional regulator
C6997_RS28420	COG0457	Tetratricopeptide repeat
C6997_RS28425	COG3710	Transcriptional regulator
C6997_RS28425	COG0457	Tetratricopeptide repeat
C6997_RS28440	COG2197	response regulator
C6997_RS28445	COG2197	response regulator
C6997_RS28530	COG3387	PFAM Glycoside hydrolase 15-related
C6997_RS28545	COG4372	Transposase
C6997_RS28550	COG3436	PFAM IS66 Orf2 family protein
C6997_RS28585	COG4974	Belongs to the 'phage' integrase family
C6997_RS28595	COG4942	peptidase
C6997_RS28605	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C6997_RS28610	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C6997_RS28615	COG2080	2 iron, 2 sulfur cluster binding
C6997_RS28620	COG3829	transcription factor binding
C6997_RS28625	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C6997_RS28630	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C6997_RS28635	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C6997_RS28645	COG0549	Belongs to the carbamate kinase family
C6997_RS28650	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C6997_RS28650	COG3608	succinylglutamate desuccinylase aspartoacylase
C6997_RS28655	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C6997_RS28660	COG2068	MobA-Related Protein
C6997_RS28665	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6997_RS28665	COG0493	'glutamate synthase
C6997_RS28670	COG0402	S-adenosylhomocysteine deaminase activity
C6997_RS28675	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C6997_RS28680	COG2080	2 iron, 2 sulfur cluster binding
C6997_RS28680	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C6997_RS28685	COG2233	PERMEase
C6997_RS28690	COG0402	S-adenosylhomocysteine deaminase activity
C6997_RS28695	COG2252	PERMEase
C6997_RS28700	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6997_RS28705	COG0493	'glutamate synthase
C6997_RS28705	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6997_RS28715	COG2233	PERMEase
C6997_RS28740	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C6997_RS28745	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C6997_RS28750	COG4974	Belongs to the 'phage' integrase family
C6997_RS28755	COG0716	FMN binding
C6997_RS28765	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
C6997_RS28775	COG1272	protein, Hemolysin III
C6997_RS28785	COG2723	6-phospho-beta-galactosidase activity
C6997_RS28790	COG1028	Short-chain dehydrogenase reductase Sdr
C6997_RS28810	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C6997_RS28815	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C6997_RS28820	COG0006	proline dipeptidase activity
C6997_RS28845	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C6997_RS28865	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C6997_RS28885	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C6997_RS28885	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C6997_RS28890	COG1703	isobutyryl-CoA mutase activity
C6997_RS28895	COG1024	Enoyl-CoA hydratase
C6997_RS28900	COG0427	acetyl-CoA hydrolase
C6997_RS28905	COG0583	DNA-binding transcription factor activity
C6997_RS28910	COG2968	Membrane
C6997_RS28920	COG0668	transmembrane transport
C6997_RS28930	COG0191	fructose-bisphosphate aldolase activity
C6997_RS28965	COG1122	ATPase activity
C6997_RS28970	COG1122	ATPase activity
C6997_RS28975	COG1072	(Pantothenic acid kinase))
C6997_RS28985	COG1494	fructose-1,6-bisphosphatase
C6997_RS28990	COG1063	alcohol dehydrogenase
C6997_RS28995	COG2213	PTS system mannitol-specific
C6997_RS29000	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6997_RS29005	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C6997_RS29010	COG0501	Belongs to the peptidase M48B family
C6997_RS29025	COG3716	PTS system mannose fructose sorbose family IID component
C6997_RS29030	COG3715	PTS system
C6997_RS29035	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6997_RS29035	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6997_RS29060	COG1166	arginine decarboxylase activity
C6997_RS29085	COG2814	Major facilitator Superfamily
C6997_RS29095	COG2356	endonuclease I
C6997_RS29100	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C6997_RS29105	COG0189	ligase activity
C6997_RS29120	COG2805	Type II/IV secretion system protein
C6997_RS29125	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C6997_RS29130	COG0762	integral membrane protein
C6997_RS29145	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C6997_RS29150	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C6997_RS29155	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
C6997_RS29170	COG0252	asparaginase activity
C6997_RS29180	COG3171	Protein conserved in bacteria
C6997_RS29195	COG1194	a g-specific adenine glycosylase
C6997_RS29210	COG2211	Major facilitator Superfamily
C6997_RS29215	COG1982	Orn Lys Arg decarboxylase major
C6997_RS29225	COG1811	Na channel or pump
C6997_RS29235	COG0582	viral genome integration into host DNA
C6997_RS29255	COG4771	TonB-dependent receptor
C6997_RS29275	COG2194	sulfuric ester hydrolase activity
C6997_RS29285	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C6997_RS29290	COG3193	protein, possibly involved in utilization of glycolate and propanediol
C6997_RS29295	COG0247	lactate metabolic process
C6997_RS29300	COG0277	FAD linked oxidase domain protein
C6997_RS29305	COG0277	FAD linked oxidase domain protein
C6997_RS29310	COG2186	Transcriptional regulator
C6997_RS29315	COG0456	acetyltransferase
C6997_RS29325	COG0318	PFAM AMP-dependent synthetase and ligase
C6997_RS29335	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C6997_RS29340	COG0156	8-amino-7-oxononanoate synthase activity
C6997_RS29350	COG0795	lipopolysaccharide-transporting ATPase activity
C6997_RS29355	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
C6997_RS29365	COG2244	polysaccharide biosynthetic process
C6997_RS29370	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C6997_RS29375	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C6997_RS29380	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C6997_RS29385	COG0306	phosphate transporter
C6997_RS29390	COG0754	glutathionylspermidine amidase activity
C6997_RS29395	COG0625	glutathione transferase activity
C6997_RS29405	COG3547	Transposase (IS116 IS110 IS902 family)
C6997_RS29410	COG0298	carbon dioxide binding
C6997_RS29420	COG1773	rubredoxin
C6997_RS29425	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C6997_RS29430	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
C6997_RS29435	COG5557	Pfam Polysulphide reductase, NrfD
C6997_RS29440	COG0437	4 iron, 4 sulfur cluster binding
C6997_RS29445	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
C6997_RS29465	COG0667	Aldo Keto reductase
C6997_RS29475	COG1028	Short-chain dehydrogenase reductase Sdr
C6997_RS29480	COG0848	biopolymer transport protein
C6997_RS29485	COG0811	peptide transport
C6997_RS29495	COG0626	cystathionine gamma-synthase activity
C6997_RS29500	COG0586	Pfam SNARE associated Golgi protein
C6997_RS29505	COG2207	Transcriptional regulator
C6997_RS29510	COG1979	alcohol dehydrogenase
C6997_RS29515	COG0656	L-ascorbic acid biosynthetic process
C6997_RS29525	COG4238	major outer membrane lipoprotein
C6997_RS29530	COG1032	radical SAM domain protein
C6997_RS29535	COG2132	Multicopper oxidase
C6997_RS29540	COG0204	Acyl-transferase
C6997_RS29545	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C6997_RS29555	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
C6997_RS29560	COG3111	PFAM Bacterial OB fold (BOF) protein
C6997_RS29565	COG0745	RESPONSE REGULATOR receiver
C6997_RS29570	COG0642	Histidine kinase
C6997_RS29580	COG2249	NAD(P)H dehydrogenase (quinone) activity
C6997_RS29585	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C6997_RS29590	COG0187	DNA topoisomerase II activity
C6997_RS29595	COG3150	esterase
C6997_RS29600	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C6997_RS29605	COG3151	Protein conserved in bacteria
C6997_RS29610	COG0494	nUDIX hydrolase
C6997_RS29615	COG1538	Outer membrane efflux protein
C6997_RS29630	COG0754	glutathionylspermidine amidase activity
C6997_RS29635	COG3384	dioxygenase
C6997_RS29655	COG2960	long-chain fatty acid transporting porin activity
C6997_RS29660	COG3539	Fimbrial protein
C6997_RS29665	COG3188	usher protein
C6997_RS29670	COG3121	Chaperone
C6997_RS29685	COG1585	Membrane protein implicated in regulation of membrane protease activity
C6997_RS29720	COG3025	triphosphatase activity
C6997_RS29730	COG4991	sh3 domain protein
C6997_RS29745	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C6997_RS29755	COG0583	DNA-binding transcription factor activity
C6997_RS29765	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C6997_RS29770	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C6997_RS29775	COG0471	metal ion transport
C6997_RS29790	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C6997_RS29795	COG0358	DNA primase activity
C6997_RS29805	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C6997_RS29820	COG2375	cellular response to nickel ion
C6997_RS29830	COG1695	Transcriptional regulator
C6997_RS29835	COG0840	transmembrane signaling receptor activity
C6997_RS29850	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C6997_RS29860	COG1609	Transcriptional regulator
C6997_RS29865	COG3250	beta-galactosidase activity
C6997_RS29870	COG2731	YhcH YjgK YiaL family protein
C6997_RS29875	COG0531	amino acid
C6997_RS29890	COG1902	pentaerythritol trinitrate reductase activity
C6997_RS29890	COG0446	pyridine nucleotide-disulphide oxidoreductase
C6997_RS29895	COG5499	transcription regulator containing HTH domain
C6997_RS29900	COG4680	protein conserved in bacteria
C6997_RS29910	COG1451	nucleotide metabolic process
C6997_RS29920	COG0673	inositol 2-dehydrogenase activity
C6997_RS29925	COG0861	Integral membrane protein TerC family
C6997_RS29930	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
C6997_RS29940	COG2721	sulfolactate sulfo-lyase activity
C6997_RS29950	COG2271	Major facilitator Superfamily
C6997_RS29980	COG2186	Transcriptional regulator
C6997_RS29985	COG0586	Pfam SNARE associated Golgi protein
C6997_RS29995	COG1422	Protein of unknown function (DUF1090)
C6997_RS30000	COG4575	ribosome binding
C6997_RS30005	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
C6997_RS30015	COG2259	Doxx family
C6997_RS30020	COG0435	Glutathione S-transferase
C6997_RS30025	COG3152	Membrane
C6997_RS30030	COG3152	Membrane
C6997_RS30040	COG0583	DNA-binding transcription factor activity
C6997_RS30045	COG1741	Belongs to the pirin family
C6997_RS30060	COG0814	amino acid
C6997_RS30070	COG1760	l-serine dehydratase
C6997_RS30075	COG0251	oxidation-reduction process
C6997_RS30080	COG1882	Formate acetyltransferase
C6997_RS30085	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C6997_RS30095	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C6997_RS30105	COG0583	DNA-binding transcription factor activity
C6997_RS30130	COG1929	Belongs to the glycerate kinase type-1 family
C6997_RS30135	COG2084	Dehydrogenase
C6997_RS30145	COG2271	Major facilitator Superfamily
C6997_RS30150	COG2721	sulfolactate sulfo-lyase activity
C6997_RS30155	COG2002	toxin-antitoxin pair type II binding
C6997_RS30165	COG1349	DNA-binding transcription factor activity
C6997_RS30180	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6997_RS30190	COG3716	PTS system mannose fructose sorbose family IID component
C6997_RS30195	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6997_RS30200	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C6997_RS30205	COG2222	sugar isomerase
C6997_RS30215	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6997_RS30220	COG3715	PTS system
C6997_RS30225	COG3716	PTS system mannose fructose sorbose family IID component
C6997_RS30230	COG0363	glucosamine-6-phosphate deaminase activity
C6997_RS30235	COG3539	Fimbrial protein
C6997_RS30240	COG3121	Chaperone
C6997_RS30245	COG3188	usher protein
C6997_RS30250	COG3539	Fimbrial protein
C6997_RS30255	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C6997_RS30275	COG2823	Periplasmic or secreted lipoprotein
C6997_RS30280	COG0701	Predicted permease
C6997_RS30285	COG0702	epimerase
C6997_RS30290	COG0693	protein deglycase activity
C6997_RS30305	COG3153	acetyltransferase
C6997_RS30310	COG3154	lipid carrier protein
C6997_RS30315	COG0826	peptidase U32
C6997_RS30320	COG0826	peptidase U32
C6997_RS30330	COG0814	amino acid
C6997_RS30335	COG0513	Belongs to the DEAD box helicase family
C6997_RS30375	COG0195	Participates in both transcription termination and antitermination
C6997_RS30395	COG2194	sulfuric ester hydrolase activity
C6997_RS30405	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C6997_RS30415	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C6997_RS30420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C6997_RS30430	COG1534	Rna-binding protein
C6997_RS30435	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C6997_RS30440	COG2027	D-alanyl-D-alanine carboxypeptidase
C6997_RS30450	COG0697	spore germination
C6997_RS30465	COG0142	geranyltranstransferase activity
C6997_RS30470	COG3423	Transcriptional regulator
C6997_RS30480	COG5007	Belongs to the BolA IbaG family
C6997_RS30485	COG3113	response to antibiotic
C6997_RS30490	COG2854	intermembrane phospholipid transfer
C6997_RS30495	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C6997_RS30500	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C6997_RS30505	COG1127	ABC transporter
C6997_RS30510	COG0530	calcium, potassium:sodium antiporter activity
C6997_RS30515	COG0517	IMP dehydrogenase activity
C6997_RS30515	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C6997_RS30520	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
C6997_RS30525	COG3117	lipopolysaccharide transmembrane transporter activity
C6997_RS30530	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
C6997_RS30535	COG1137	ATPase activity
C6997_RS30540	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C6997_RS30545	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C6997_RS30560	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6997_RS30565	COG0515	serine threonine protein kinase
C6997_RS30575	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
C6997_RS30580	COG0784	Response regulator, receiver
C6997_RS30580	COG2198	Histidine kinase
C6997_RS30580	COG5002	protein histidine kinase activity
C6997_RS30610	COG1585	Membrane protein implicated in regulation of membrane protease activity
C6997_RS30625	COG3468	outer membrane autotransporter barrel domain protein
C6997_RS30655	COG3436	PFAM IS66 Orf2 family protein
C6997_RS30660	COG4372	Transposase
C6997_RS30680	COG3436	PFAM IS66 Orf2 family protein
C6997_RS30685	COG4372	Transposase
C6997_RS30695	COG1560	Kdo2-lipid A biosynthetic process
C6997_RS30705	COG0297	glycogen (starch) synthase activity
C6997_RS30710	COG0726	polysaccharide deacetylase
C6997_RS30740	COG2274	protein secretion by the type I secretion system
C6997_RS30820	COG3436	PFAM IS66 Orf2 family protein
C6997_RS30825	COG4372	Transposase
C6997_RS30945	COG4372	Transposase
C6997_RS30950	COG3436	PFAM IS66 Orf2 family protein