locus-tag	class	description
C6P53_RS00005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6P53_RS00015	COG1278	Cold shock
C6P53_RS00045	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C6P53_RS00050	COG4988	ABC transporter
C6P53_RS00055	COG0492	ferredoxin-NADP+ reductase activity
C6P53_RS00065	COG1522	sequence-specific DNA binding
C6P53_RS00090	COG0243	molybdopterin cofactor binding
C6P53_RS00095	COG0437	4 iron, 4 sulfur cluster binding
C6P53_RS00100	COG3302	dmso reductase anchor subunit
C6P53_RS00105	COG1335	isochorismatase
C6P53_RS00120	COG0583	DNA-binding transcription factor activity
C6P53_RS00125	COG2249	NAD(P)H dehydrogenase (quinone) activity
C6P53_RS00130	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C6P53_RS00135	COG1882	Formate acetyltransferase
C6P53_RS00145	COG1944	ATP diphosphatase activity
C6P53_RS00150	COG2323	membrane
C6P53_RS00165	COG0501	Belongs to the peptidase M48B family
C6P53_RS00175	COG0539	negative regulation of cytoplasmic translation
C6P53_RS00185	COG2333	competence protein COMEC
C6P53_RS00185	COG0658	competence protein
C6P53_RS00190	COG1132	(ABC) transporter
C6P53_RS00200	COG3214	Protein conserved in bacteria
C6P53_RS00215	COG3173	Aminoglycoside phosphotransferase
C6P53_RS00220	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C6P53_RS00225	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C6P53_RS00235	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
C6P53_RS00245	COG2989	Protein conserved in bacteria
C6P53_RS00255	COG3108	Peptidase M15
C6P53_RS00260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C6P53_RS00275	COG1448	Aminotransferase
C6P53_RS00295	COG0308	aminopeptidase N
C6P53_RS00305	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C6P53_RS00320	COG0431	NADPH-dependent FMN reductase
C6P53_RS00335	COG3121	Chaperone
C6P53_RS00340	COG3188	usher protein
C6P53_RS00345	COG3539	Fimbrial protein
C6P53_RS00350	COG3539	Fimbrial protein
C6P53_RS00355	COG3539	Fimbrial protein
C6P53_RS00360	COG3121	Chaperone
C6P53_RS00375	COG0633	Ferredoxin
C6P53_RS00375	COG3217	Mosc domain protein beta barrel domain protein
C6P53_RS00405	COG3130	regulation of translation
C6P53_RS00415	COG1067	ATP-dependent peptidase activity
C6P53_RS00440	COG3070	regulator of competence-specific genes
C6P53_RS00445	COG1289	transmembrane transporter activity
C6P53_RS00450	COG3304	Inner membrane component domain
C6P53_RS00470	COG1832	CoA-binding protein
C6P53_RS00490	COG2920	part of a sulfur-relay system
C6P53_RS00495	COG0670	Belongs to the BI1 family
C6P53_RS00560	COG1396	sequence-specific DNA binding
C6P53_RS00585	COG1846	Transcriptional regulator
C6P53_RS00630	COG1403	HNH endonuclease
C6P53_RS00635	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C6P53_RS00640	COG0484	heat shock protein binding
C6P53_RS00740	COG0740	serine-type endopeptidase activity
C6P53_RS00830	COG0727	PFAM Uncharacterised protein family (UPF0153)
C6P53_RS00840	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
C6P53_RS00845	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
C6P53_RS00850	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
C6P53_RS00855	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C6P53_RS00860	COG1999	signal sequence binding
C6P53_RS00865	COG1773	rubredoxin
C6P53_RS00890	COG3206	protein involved in exopolysaccharide biosynthesis
C6P53_RS00890	COG0489	protein tyrosine kinase activity
C6P53_RS00895	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C6P53_RS00900	COG1596	polysaccharide export
C6P53_RS00905	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C6P53_RS00925	COG1278	Cold shock
C6P53_RS00930	COG1278	Cold shock
C6P53_RS00950	COG0348	domain, Protein
C6P53_RS00955	COG0784	Response regulator, receiver
C6P53_RS00955	COG2205	protein histidine kinase activity
C6P53_RS00955	COG2198	Histidine kinase
C6P53_RS00965	COG0745	RESPONSE REGULATOR receiver
C6P53_RS00970	COG3005	denitrification pathway
C6P53_RS01020	COG3729	General stress protein
C6P53_RS01025	COG2233	PERMEase
C6P53_RS01110	COG1702	phosphate starvation-inducible protein PhoH
C6P53_RS01115	COG3658	cytochrome
C6P53_RS01120	COG1215	transferase activity, transferring glycosyl groups
C6P53_RS01125	COG1649	PFAM Uncharacterised BCR, COG1649
C6P53_RS01125	COG0726	polysaccharide deacetylase
C6P53_RS01195	COG1462	curli production assembly transport component CsgG
C6P53_RS01245	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C6P53_RS01250	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C6P53_RS01280	COG5645	(Lipo)protein
C6P53_RS01295	COG1560	Kdo2-lipid A biosynthetic process
C6P53_RS01305	COG2353	YceI-like domain
C6P53_RS01310	COG3038	cytochrome b561
C6P53_RS01350	COG2999	glutathione oxidoreductase activity
C6P53_RS01360	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C6P53_RS01370	COG0673	inositol 2-dehydrogenase activity
C6P53_RS01375	COG0728	peptidoglycan biosynthetic process
C6P53_RS01380	COG3418	PFAM FlgN family protein
C6P53_RS01385	COG2747	anti-sigma28 factor FlgM
C6P53_RS01390	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
C6P53_RS01395	COG1815	bacterial-type flagellum-dependent cell motility
C6P53_RS01400	COG1815	bacterial-type flagellum-dependent cell motility
C6P53_RS01405	COG1558	bacterial-type flagellum-dependent cell motility
C6P53_RS01410	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C6P53_RS01415	COG1749	Flagellar hook protein flgE
C6P53_RS01425	COG4787	bacterial-type flagellum-dependent cell motility
C6P53_RS01445	COG1705	Flagellar rod assembly protein muramidase FlgJ
C6P53_RS01445	COG3951	Flagellar rod assembly protein muramidase FlgJ
C6P53_RS01450	COG1256	bacterial-type flagellum assembly
C6P53_RS01455	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C6P53_RS01475	COG0424	maF-like protein
C6P53_RS01480	COG1399	metal-binding, possibly nucleic acid-binding protein
C6P53_RS01500	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C6P53_RS01505	COG1028	Short-chain dehydrogenase reductase Sdr
C6P53_RS01515	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C6P53_RS01520	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C6P53_RS01525	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C6P53_RS01535	COG0470	DNA polymerase III
C6P53_RS01550	COG4773	Receptor
C6P53_RS01555	COG0537	adenosine 5'-monophosphoramidase activity
C6P53_RS01565	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
C6P53_RS01595	COG3134	Outer membrane lipoprotein
C6P53_RS01610	COG1376	ErfK ybiS ycfS ynhG family protein
C6P53_RS01610	COG1388	LysM domain
C6P53_RS01620	COG4763	Acyl-transferase
C6P53_RS01625	COG4591	ABC-type transport system involved in lipoprotein release permease component
C6P53_RS01630	COG1136	(ABC) transporter
C6P53_RS01645	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C6P53_RS01660	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C6P53_RS01665	COG1177	transmembrane transport
C6P53_RS01670	COG0582	viral genome integration into host DNA
C6P53_RS01680	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6P53_RS01720	COG4197	protein conserved in bacteria, prophage-related
C6P53_RS01795	COG1403	HNH endonuclease
C6P53_RS01800	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C6P53_RS01825	COG3064	Membrane
C6P53_RS01835	COG2207	Transcriptional regulator
C6P53_RS01855	COG3772	lysozyme
C6P53_RS01980	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6P53_RS01980	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6P53_RS01995	COG0727	PFAM Uncharacterised protein family (UPF0153)
C6P53_RS02020	COG2850	peptidyl-arginine hydroxylation
C6P53_RS02025	COG2205	protein histidine kinase activity
C6P53_RS02035	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C6P53_RS02055	COG1187	pseudouridine synthase activity
C6P53_RS02070	COG5562	phage envelope protein
C6P53_RS02075	COG0789	Transcriptional regulator
C6P53_RS02080	COG2200	EAL domain
C6P53_RS02105	COG2200	EAL domain
C6P53_RS02165	COG2894	cell division
C6P53_RS02200	COG0179	Fumarylacetoacetate (FAA) hydrolase
C6P53_RS02215	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C6P53_RS02225	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C6P53_RS02240	COG2719	SpoVR family
C6P53_RS02250	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C6P53_RS02265	COG1619	proteins homologs of microcin C7 resistance protein MccF
C6P53_RS02310	COG1461	Dihydroxyacetone kinase
C6P53_RS02315	COG2376	Dihydroxyacetone kinase
C6P53_RS02325	COG3468	outer membrane autotransporter barrel domain protein
C6P53_RS02340	COG0012	GTP binding
C6P53_RS02355	COG0659	secondary active sulfate transmembrane transporter activity
C6P53_RS02365	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C6P53_RS02395	COG2890	protein-(glutamine-N5) methyltransferase activity
C6P53_RS02400	COG3094	Invasion gene expression up-regulator, SirB
C6P53_RS02435	COG0387	Pfam Sodium calcium exchanger
C6P53_RS02440	COG4572	Cation transport regulator
C6P53_RS02445	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
C6P53_RS02450	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
C6P53_RS02455	COG4932	domain protein
C6P53_RS02460	COG2197	response regulator
C6P53_RS02465	COG3850	Histidine kinase
C6P53_RS02475	COG2223	nitrite transmembrane transporter activity
C6P53_RS02480	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C6P53_RS02485	COG1140	nitrate reductase beta subunit
C6P53_RS02490	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C6P53_RS02495	COG2181	nitrate reductase activity
C6P53_RS02520	COG0788	formyltetrahydrofolate deformylase activity
C6P53_RS02530	COG1752	Esterase of the alpha-beta hydrolase superfamily
C6P53_RS02535	COG0745	RESPONSE REGULATOR receiver
C6P53_RS02550	COG1435	thymidine kinase activity
C6P53_RS02575	COG4166	transmembrane transport
C6P53_RS02585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C6P53_RS02590	COG0444	Belongs to the ABC transporter superfamily
C6P53_RS02620	COG2350	Protein conserved in bacteria
C6P53_RS02625	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
C6P53_RS02630	COG1607	acyl-coa hydrolase
C6P53_RS02650	COG3047	cAMP biosynthetic process
C6P53_RS02655	COG0582	viral genome integration into host DNA
C6P53_RS02665	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6P53_RS02770	COG1403	HNH endonuclease
C6P53_RS02775	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C6P53_RS02805	COG2207	Transcriptional regulator
C6P53_RS02825	COG3772	lysozyme
C6P53_RS02975	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6P53_RS02975	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6P53_RS03020	COG3685	Protein conserved in bacteria
C6P53_RS03025	COG3685	Protein conserved in bacteria
C6P53_RS03030	COG3729	General stress protein
C6P53_RS03050	COG0512	Glutamine amidotransferase of anthranilate synthase
C6P53_RS03050	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C6P53_RS03055	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C6P53_RS03065	COG0613	PHP domain protein
C6P53_RS03070	COG0009	L-threonylcarbamoyladenylate synthase
C6P53_RS03075	COG1187	pseudouridine synthase activity
C6P53_RS03080	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
C6P53_RS03085	COG1028	Short-chain dehydrogenase reductase Sdr
C6P53_RS03090	COG0616	signal peptide processing
C6P53_RS03115	COG0583	DNA-binding transcription factor activity
C6P53_RS03145	COG0671	phosphoesterase, PA-phosphatase related
C6P53_RS03150	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
C6P53_RS03155	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
C6P53_RS03165	COG0023	Translation Initiation Factor
C6P53_RS03175	COG1349	DNA-binding transcription factor activity
C6P53_RS03200	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C6P53_RS03200	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C6P53_RS03205	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C6P53_RS03210	COG2852	Protein conserved in bacteria
C6P53_RS03215	COG4172	Belongs to the ABC transporter superfamily
C6P53_RS03220	COG4172	Belongs to the ABC transporter superfamily
C6P53_RS03225	COG4171	peptide transport system, permease
C6P53_RS03230	COG4168	peptide transport system, permease
C6P53_RS03235	COG4166	transmembrane transport
C6P53_RS03255	COG0174	glutamine synthetase
C6P53_RS03265	COG1917	Cupin 2, conserved barrel domain protein
C6P53_RS03265	COG1396	sequence-specific DNA binding
C6P53_RS03280	COG1012	belongs to the aldehyde dehydrogenase family
C6P53_RS03285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C6P53_RS03290	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C6P53_RS03295	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C6P53_RS03300	COG1842	Phage shock protein A
C6P53_RS03310	COG1983	PspC domain protein
C6P53_RS03320	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C6P53_RS03335	COG1175	transmembrane transport
C6P53_RS03340	COG0395	ABC-type sugar transport system, permease component
C6P53_RS03345	COG1063	alcohol dehydrogenase
C6P53_RS03350	COG1082	Xylose isomerase domain protein TIM barrel
C6P53_RS03365	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C6P53_RS03370	COG3842	ATPase activity
C6P53_RS03380	COG1609	Transcriptional regulator
C6P53_RS03385	COG3106	COG3106 Predicted ATPase
C6P53_RS03395	COG3283	Transcriptional regulator of aromatic amino acids metabolism
C6P53_RS03400	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
C6P53_RS03405	COG4948	Mandelate Racemase Muconate Lactonizing
C6P53_RS03410	COG2866	Carboxypeptidase
C6P53_RS03415	COG0702	epimerase
C6P53_RS03420	COG1073	alpha beta
C6P53_RS03425	COG1073	alpha beta
C6P53_RS03430	COG0583	DNA-binding transcription factor activity
C6P53_RS03435	COG4166	transmembrane transport
C6P53_RS03440	COG0668	transmembrane transport
C6P53_RS03445	COG3182	Iron-regulated membrane protein
C6P53_RS03455	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C6P53_RS03465	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
C6P53_RS03475	COG1473	amidohydrolase
C6P53_RS03485	COG0583	DNA-binding transcription factor activity
C6P53_RS03490	COG2840	Smr protein MutS2
C6P53_RS03495	COG3706	GGDEF domain
C6P53_RS03510	COG0513	Belongs to the DEAD box helicase family
C6P53_RS03520	COG0589	response to stress
C6P53_RS03525	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C6P53_RS03540	COG3042	response to heat
C6P53_RS03545	COG3187	Heat shock protein
C6P53_RS03580	COG3733	amine oxidase
C6P53_RS03585	COG1012	belongs to the aldehyde dehydrogenase family
C6P53_RS03585	COG2030	dehydratase
C6P53_RS03595	COG3460	Phenylacetate-CoA oxygenase
C6P53_RS03605	COG2151	metal-sulfur cluster biosynthetic enzyme
C6P53_RS03610	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C6P53_RS03615	COG1024	Enoyl-CoA hydratase
C6P53_RS03620	COG1024	Enoyl-CoA hydratase
C6P53_RS03625	COG1250	3-hydroxyacyl-CoA dehydrogenase
C6P53_RS03630	COG2050	protein possibly involved in aromatic compounds catabolism
C6P53_RS03635	COG0183	Belongs to the thiolase family
C6P53_RS03645	COG3327	negative regulation of DNA-templated transcription, initiation
C6P53_RS03665	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C6P53_RS03670	COG4589	Belongs to the CDS family
C6P53_RS03675	COG2267	carboxylic ester hydrolase activity
C6P53_RS03680	COG0671	phosphoesterase, PA-phosphatase related
C6P53_RS03680	COG2453	phosphatase
C6P53_RS03695	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C6P53_RS03705	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C6P53_RS03710	COG3038	cytochrome b561
C6P53_RS03725	COG0840	transmembrane signaling receptor activity
C6P53_RS03730	COG0583	DNA-binding transcription factor activity
C6P53_RS03735	COG5383	Protein conserved in bacteria
C6P53_RS03755	COG2841	Protein conserved in bacteria
C6P53_RS03760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C6P53_RS03770	COG1275	C4-dicarboxylate transporter malic acid transport protein
C6P53_RS03775	COG0500	methyltransferase
C6P53_RS03790	COG0675	Transposase, IS605 OrfB family
C6P53_RS03795	COG3135	benzoate transporter
C6P53_RS03800	COG1396	sequence-specific DNA binding
C6P53_RS03805	COG0826	peptidase U32
C6P53_RS03820	COG1598	PFAM Uncharacterised protein family UPF0150
C6P53_RS03825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C6P53_RS03830	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C6P53_RS03835	COG3842	ATPase activity
C6P53_RS03840	COG1176	ABC-type spermidine putrescine transport system, permease component I
C6P53_RS03845	COG1177	transmembrane transport
C6P53_RS03880	COG3238	Protein conserved in bacteria
C6P53_RS03885	COG1247	-acetyltransferase
C6P53_RS03895	COG2130	NADP-dependent
C6P53_RS03900	COG1802	Transcriptional regulator
C6P53_RS03920	COG3391	amine dehydrogenase activity
C6P53_RS03930	COG0625	glutathione transferase activity
C6P53_RS03965	COG5433	transposase activity
C6P53_RS04005	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C6P53_RS04010	COG2162	N-hydroxyarylamine O-acetyltransferase activity
C6P53_RS04015	COG0384	phenazine biosynthesis protein PhzF
C6P53_RS04020	COG2181	nitrate reductase activity
C6P53_RS04025	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C6P53_RS04035	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C6P53_RS04040	COG2223	nitrite transmembrane transporter activity
C6P53_RS04045	COG4886	Leucine-rich repeat (LRR) protein
C6P53_RS04050	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C6P53_RS04055	COG0697	spore germination
C6P53_RS04060	COG3383	formate dehydrogenase (NAD+) activity
C6P53_RS04060	COG0243	molybdopterin cofactor binding
C6P53_RS04065	COG3383	formate dehydrogenase (NAD+) activity
C6P53_RS04065	COG0243	molybdopterin cofactor binding
C6P53_RS04070	COG0437	4 iron, 4 sulfur cluster binding
C6P53_RS04075	COG2864	formate dehydrogenase
C6P53_RS04080	COG3093	addiction module antidote protein HigA
C6P53_RS04085	COG1064	alcohol dehydrogenase
C6P53_RS04110	COG1764	response to oxidative stress
C6P53_RS04115	COG4608	Belongs to the ABC transporter superfamily
C6P53_RS04120	COG0444	Belongs to the ABC transporter superfamily
C6P53_RS04125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C6P53_RS04130	COG0601	transmembrane transport
C6P53_RS04135	COG0747	negative chemotaxis
C6P53_RS04140	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
C6P53_RS04145	COG2199	diguanylate cyclase activity
C6P53_RS04145	COG2200	EAL domain
C6P53_RS04145	COG2202	Pas domain
C6P53_RS04155	COG1649	PFAM Uncharacterised BCR, COG1649
C6P53_RS04160	COG0531	amino acid
C6P53_RS04165	COG0076	glutamate decarboxylase activity
C6P53_RS04170	COG0612	Peptidase, M16
C6P53_RS04175	COG4771	TonB-dependent receptor
C6P53_RS04180	COG4178	(ABC) transporter
C6P53_RS04185	COG0641	radical SAM
C6P53_RS04190	COG3119	arylsulfatase activity
C6P53_RS04195	COG2207	Transcriptional regulator
C6P53_RS04205	COG0243	molybdopterin cofactor binding
C6P53_RS04215	COG3539	Fimbrial protein
C6P53_RS04220	COG3539	Fimbrial protein
C6P53_RS04225	COG3188	usher protein
C6P53_RS04235	COG3539	Fimbrial protein
C6P53_RS04250	COG3550	peptidyl-serine autophosphorylation
C6P53_RS04255	COG1396	sequence-specific DNA binding
C6P53_RS04315	COG3781	membrane
C6P53_RS04335	COG2199	diguanylate cyclase activity
C6P53_RS04350	COG2066	Belongs to the glutaminase family
C6P53_RS04355	COG1012	belongs to the aldehyde dehydrogenase family
C6P53_RS04385	COG1846	Transcriptional regulator
C6P53_RS04390	COG4977	sequence-specific DNA binding
C6P53_RS04410	COG1447	Phosphotransferase system cellobiose-specific component IIA
C6P53_RS04415	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C6P53_RS04425	COG2188	Transcriptional regulator
C6P53_RS04430	COG0697	spore germination
C6P53_RS04435	COG2814	Major facilitator Superfamily
C6P53_RS04445	COG3706	GGDEF domain
C6P53_RS04450	COG3111	PFAM Bacterial OB fold (BOF) protein
C6P53_RS04455	COG1546	Belongs to the CinA family
C6P53_RS04465	COG0339	signal peptide processing
C6P53_RS04475	COG4221	oxidoreductase activity
C6P53_RS04480	COG1802	Transcriptional regulator
C6P53_RS04490	COG0246	Mannitol dehydrogenase
C6P53_RS04495	COG0477	Major facilitator Superfamily
C6P53_RS04500	COG0477	Major facilitator Superfamily
C6P53_RS04505	COG1063	alcohol dehydrogenase
C6P53_RS04545	COG0243	molybdopterin cofactor binding
C6P53_RS04555	COG0437	4 iron, 4 sulfur cluster binding
C6P53_RS04565	COG3561	AntA/AntB antirepressor
C6P53_RS04600	COG3111	PFAM Bacterial OB fold (BOF) protein
C6P53_RS04740	COG3772	lysozyme
C6P53_RS04855	COG1846	Transcriptional regulator
C6P53_RS04860	COG1484	DNA-dependent DNA replication
C6P53_RS04945	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6P53_RS04980	COG0582	viral genome integration into host DNA
C6P53_RS04985	COG0437	4 iron, 4 sulfur cluster binding
C6P53_RS04990	COG3302	dmso reductase anchor subunit
C6P53_RS04995	COG3381	protein complex oligomerization
C6P53_RS05005	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C6P53_RS05020	COG2814	Major facilitator Superfamily
C6P53_RS05040	COG3591	Belongs to the peptidase S1B family
C6P53_RS05060	COG0628	permease
C6P53_RS05065	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
C6P53_RS05070	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
C6P53_RS05085	COG0531	amino acid
C6P53_RS05095	COG3136	membrane protein required for alginate biosynthesis
C6P53_RS05100	COG0745	RESPONSE REGULATOR receiver
C6P53_RS05115	COG0114	fumarate hydratase activity
C6P53_RS05120	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C6P53_RS05120	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C6P53_RS05125	COG1482	cell wall glycoprotein biosynthetic process
C6P53_RS05130	COG5339	Protein conserved in bacteria
C6P53_RS05145	COG3250	beta-galactosidase activity
C6P53_RS05155	COG1028	Short-chain dehydrogenase reductase Sdr
C6P53_RS05160	COG1609	Transcriptional regulator
C6P53_RS05165	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6P53_RS05165	COG1263	PTS System
C6P53_RS05180	COG0673	inositol 2-dehydrogenase activity
C6P53_RS05235	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C6P53_RS05245	COG3104	oligopeptide transport
C6P53_RS05250	COG0625	glutathione transferase activity
C6P53_RS05270	COG3895	Periplasmic Protein
C6P53_RS05280	COG3133	Outer membrane lipoprotein
C6P53_RS05300	COG1289	transmembrane transporter activity
C6P53_RS05310	COG4989	oxidoreductase activity
C6P53_RS05315	COG3313	Fe-S protein
C6P53_RS05320	COG1309	transcriptional regulator
C6P53_RS05325	COG1902	pentaerythritol trinitrate reductase activity
C6P53_RS05330	COG0346	lactoylglutathione lyase activity
C6P53_RS05345	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C6P53_RS05350	COG0791	NLP P60 protein
C6P53_RS05360	COG2814	Major facilitator Superfamily
C6P53_RS05380	COG0583	DNA-binding transcription factor activity
C6P53_RS05385	COG2814	Major facilitator Superfamily
C6P53_RS05395	COG0307	riboflavin synthase, alpha
C6P53_RS05425	COG4529	Protein conserved in bacteria
C6P53_RS05435	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
C6P53_RS05440	COG0437	4 iron, 4 sulfur cluster binding
C6P53_RS05450	COG2414	aldehyde ferredoxin oxidoreductase
C6P53_RS05455	COG0437	4 iron, 4 sulfur cluster binding
C6P53_RS05465	COG0469	pyruvate kinase activity
C6P53_RS05470	COG4238	major outer membrane lipoprotein
C6P53_RS05475	COG1376	ErfK ybiS ycfS ynhG family protein
C6P53_RS05490	COG0719	Fe-S assembly protein
C6P53_RS05495	COG0396	ATPase activity
C6P53_RS05505	COG0316	Belongs to the HesB IscA family
C6P53_RS05515	COG2050	protein possibly involved in aromatic compounds catabolism
C6P53_RS05520	COG0247	lactate metabolic process
C6P53_RS05520	COG0277	FAD linked oxidase domain protein
C6P53_RS05530	COG0628	permease
C6P53_RS05545	COG0738	Major facilitator superfamily
C6P53_RS05550	COG2271	Major facilitator Superfamily
C6P53_RS05565	COG4670	ketone body catabolic process
C6P53_RS05575	COG1917	Cupin 2, conserved barrel domain protein
C6P53_RS05575	COG2207	Transcriptional regulator
C6P53_RS05585	COG2086	electron transfer activity
C6P53_RS05590	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C6P53_RS05600	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C6P53_RS05605	COG0318	PFAM AMP-dependent synthetase and ligase
C6P53_RS05610	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C6P53_RS05610	COG0574	Belongs to the PEP-utilizing enzyme family
C6P53_RS05625	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C6P53_RS05630	COG4256	Hemin uptake protein
C6P53_RS05640	COG2200	EAL domain
C6P53_RS05645	COG0791	NLP P60 protein
C6P53_RS05655	COG0386	Belongs to the glutathione peroxidase family
C6P53_RS05740	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C6P53_RS05745	COG1988	membrane-bound metal-dependent
C6P53_RS05750	COG1823	symporter activity
C6P53_RS05770	COG0753	catalase activity
C6P53_RS05775	COG3547	Transposase (IS116 IS110 IS902 family)
C6P53_RS05790	COG1486	melibiose metabolic process
C6P53_RS05800	COG1447	Phosphotransferase system cellobiose-specific component IIA
C6P53_RS05805	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C6P53_RS05810	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C6P53_RS05820	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C6P53_RS05830	COG0322	excinuclease ABC activity
C6P53_RS05840	COG3678	ATP-independent chaperone mediated protein folding
C6P53_RS05875	COG0708	Exodeoxyribonuclease III
C6P53_RS05880	COG0398	Pfam SNARE associated Golgi protein
C6P53_RS05900	COG4134	Bacterial extracellular solute-binding protein
C6P53_RS05910	COG4136	ATPase activity
C6P53_RS05920	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C6P53_RS05925	COG0494	nUDIX hydrolase
C6P53_RS05935	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C6P53_RS05960	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C6P53_RS05965	COG0709	Synthesizes selenophosphate from selenide and ATP
C6P53_RS05975	COG0778	Nitroreductase
C6P53_RS05985	COG0616	signal peptide processing
C6P53_RS05990	COG0252	asparaginase activity
C6P53_RS05995	COG1335	isochorismatase
C6P53_RS06000	COG2814	Major facilitator Superfamily
C6P53_RS06005	COG1349	DNA-binding transcription factor activity
C6P53_RS06010	COG0667	Aldo Keto reductase
C6P53_RS06015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6P53_RS06020	COG0191	fructose-bisphosphate aldolase activity
C6P53_RS06025	COG1063	alcohol dehydrogenase
C6P53_RS06030	COG2271	Major facilitator Superfamily
C6P53_RS06040	COG3139	Protein of unknown function (DUF1315)
C6P53_RS06050	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C6P53_RS06055	COG0676	glucose-6-phosphate 1-epimerase activity
C6P53_RS06060	COG0656	L-ascorbic acid biosynthetic process
C6P53_RS06065	COG3713	MltA-interacting MipA family protein
C6P53_RS06085	COG2199	diguanylate cyclase activity
C6P53_RS06090	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C6P53_RS06105	COG2207	Transcriptional regulator
C6P53_RS06115	COG3189	MarR family transcriptional regulator
C6P53_RS06120	COG3042	response to heat
C6P53_RS06125	COG2203	Gaf domain
C6P53_RS06125	COG2199	diguanylate cyclase activity
C6P53_RS06140	COG2261	transglycosylase associated protein
C6P53_RS06145	COG0675	Transposase, IS605 OrfB family
C6P53_RS06160	COG3615	Tellurite resistance protein tehB
C6P53_RS06170	COG0583	DNA-binding transcription factor activity
C6P53_RS06175	COG0473	3-isopropylmalate dehydrogenase activity
C6P53_RS06180	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C6P53_RS06185	COG4638	Rieske (2fe-2S)
C6P53_RS06190	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C6P53_RS06195	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
C6P53_RS06205	COG3065	identical protein binding
C6P53_RS06215	COG1199	ATP-dependent helicase activity
C6P53_RS06220	COG0251	oxidation-reduction process
C6P53_RS06250	COG2200	EAL domain
C6P53_RS06255	COG1253	flavin adenine dinucleotide binding
C6P53_RS06275	COG3715	PTS system
C6P53_RS06280	COG3716	PTS system mannose fructose sorbose family IID component
C6P53_RS06300	COG2226	methyltransferase
C6P53_RS06335	COG1414	Transcriptional regulator
C6P53_RS06350	COG0793	Belongs to the peptidase S41A family
C6P53_RS06360	COG1956	GAF domain-containing protein
C6P53_RS06365	COG2995	paraquat-inducible protein a
C6P53_RS06370	COG3008	intermembrane lipid transfer
C6P53_RS06390	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C6P53_RS06405	COG2372	response to copper ion
C6P53_RS06415	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C6P53_RS06420	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6P53_RS06425	COG1770	oligopeptidase
C6P53_RS06430	COG2979	Protein of unknown function (DUF533)
C6P53_RS06440	COG3141	response to X-ray
C6P53_RS06450	COG0800	Aldolase
C6P53_RS06455	COG0129	dihydroxy-acid dehydratase activity
C6P53_RS06460	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C6P53_RS06470	COG0469	pyruvate kinase activity
C6P53_RS06475	COG1560	Kdo2-lipid A biosynthetic process
C6P53_RS06480	COG0739	heme binding
C6P53_RS06485	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
C6P53_RS06495	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C6P53_RS06525	COG0217	transcriptional regulatory protein
C6P53_RS06530	COG0494	nUDIX hydrolase
C6P53_RS06540	COG1335	isochorismatase
C6P53_RS06550	COG3788	relative of glutathione S-transferase, MAPEG superfamily
C6P53_RS06570	COG3005	denitrification pathway
C6P53_RS06580	COG3102	Protein conserved in bacteria
C6P53_RS06595	COG3755	Protein conserved in bacteria
C6P53_RS06605	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C6P53_RS06610	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C6P53_RS06615	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
C6P53_RS06620	COG0745	RESPONSE REGULATOR receiver
C6P53_RS06630	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C6P53_RS06640	COG0840	transmembrane signaling receptor activity
C6P53_RS06650	COG0643	Histidine kinase
C6P53_RS06650	COG2198	Histidine kinase
C6P53_RS06655	COG1360	Flagellar Motor Protein
C6P53_RS06660	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C6P53_RS06675	COG0589	response to stress
C6P53_RS06685	COG1877	trehalose-phosphatase activity
C6P53_RS06690	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6P53_RS06700	COG1879	ABC-type sugar transport system periplasmic component
C6P53_RS06710	COG1528	Iron-storage protein
C6P53_RS06735	COG1528	Iron-storage protein
C6P53_RS06745	COG0814	amino acid
C6P53_RS06780	COG2197	response regulator
C6P53_RS06790	COG2197	response regulator
C6P53_RS06795	COG1126	abc transporter atp-binding protein
C6P53_RS06800	COG0765	amino acid transport
C6P53_RS06810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6P53_RS06820	COG1191	sigma factor activity
C6P53_RS06840	COG1516	flagellar protein fliS
C6P53_RS06870	COG0425	Belongs to the sulfur carrier protein TusA family
C6P53_RS06875	COG2135	peptidase activity
C6P53_RS06880	COG0675	Transposase, IS605 OrfB family
C6P53_RS06895	COG2207	Transcriptional regulator
C6P53_RS06900	COG1881	PFAM PEBP family protein
C6P53_RS06905	COG2076	Multidrug Resistance protein
C6P53_RS06920	COG1766	The M ring may be actively involved in energy transduction
C6P53_RS06925	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C6P53_RS06930	COG1317	bacterial-type flagellum organization
C6P53_RS06935	COG1157	protein secretion by the type III secretion system
C6P53_RS06940	COG2882	bacterial-type flagellum organization
C6P53_RS06950	COG1580	Controls the rotational direction of flagella during chemotaxis
C6P53_RS06955	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C6P53_RS06960	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C6P53_RS06965	COG3190	flagellar
C6P53_RS06970	COG1338	Plays a role in the flagellum-specific transport system
C6P53_RS06975	COG1987	bacterial-type flagellum assembly
C6P53_RS06985	COG2197	response regulator
C6P53_RS07015	COG5475	Uncharacterized small protein (DUF2158)
C6P53_RS07020	COG2354	Protein conserved in bacteria
C6P53_RS07025	COG0697	spore germination
C6P53_RS07035	COG0270	DNA (cytosine-5-)-methyltransferase activity
C6P53_RS07040	COG1418	mRNA catabolic process
C6P53_RS07070	COG0745	RESPONSE REGULATOR receiver
C6P53_RS07075	COG2351	hydroxyisourate hydrolase activity
C6P53_RS07090	COG3443	Belongs to the bacterial solute-binding protein 9 family
C6P53_RS07095	COG3038	cytochrome b561
C6P53_RS07125	COG4932	domain protein
C6P53_RS07125	COG2373	Large extracellular alpha-helical protein
C6P53_RS07125	COG1388	LysM domain
C6P53_RS07165	COG0217	transcriptional regulatory protein
C6P53_RS07195	COG0582	viral genome integration into host DNA
C6P53_RS07205	COG5290	Psort location Cytoplasmic, score
C6P53_RS07220	COG0583	DNA-binding transcription factor activity
C6P53_RS07235	COG1376	ErfK ybiS ycfS ynhG family protein
C6P53_RS07250	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
C6P53_RS07310	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
C6P53_RS07325	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
C6P53_RS07340	COG1454	alcohol dehydrogenase
C6P53_RS07340	COG1012	belongs to the aldehyde dehydrogenase family
C6P53_RS07370	COG1289	transmembrane transporter activity
C6P53_RS07380	COG1686	Belongs to the peptidase S11 family
C6P53_RS07390	COG0425	Belongs to the sulfur carrier protein TusA family
C6P53_RS07395	COG2391	methyltransferase activity
C6P53_RS07410	COG0583	DNA-binding transcription factor activity
C6P53_RS07420	COG4115	mRNA cleavage
C6P53_RS07425	COG2161	toxin-antitoxin pair type II binding
C6P53_RS07455	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C6P53_RS07455	COG0131	Imidazoleglycerol-phosphate dehydratase
C6P53_RS07460	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C6P53_RS07495	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C6P53_RS07500	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C6P53_RS07510	COG0463	Glycosyl transferase, family 2
C6P53_RS07510	COG1216	Glycosyl transferase, family 2
C6P53_RS07520	COG0110	maltose O-acetyltransferase activity
C6P53_RS07535	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C6P53_RS07540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C6P53_RS07550	COG0438	transferase activity, transferring glycosyl groups
C6P53_RS07555	COG2327	Polysaccharide pyruvyl transferase
C6P53_RS07570	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C6P53_RS07575	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
C6P53_RS07575	COG0662	Cupin 2, conserved barrel domain protein
C6P53_RS07590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C6P53_RS07595	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
C6P53_RS07605	COG1216	Glycosyl transferase, family 2
C6P53_RS07615	COG0438	transferase activity, transferring glycosyl groups
C6P53_RS07620	COG1045	serine acetyltransferase
C6P53_RS07625	COG0463	Glycosyl transferase, family 2
C6P53_RS07635	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C6P53_RS07640	COG1596	polysaccharide export
C6P53_RS07650	COG2982	Protein involved in outer membrane biogenesis
C6P53_RS07660	COG0572	uridine kinase
C6P53_RS07665	COG3447	MASE1 domain protein
C6P53_RS07665	COG5002	protein histidine kinase activity
C6P53_RS07665	COG5001	Diguanylate cyclase
C6P53_RS07670	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C6P53_RS07680	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
C6P53_RS07685	COG0631	protein serine/threonine phosphatase activity
C6P53_RS07690	COG4245	von Willebrand factor, type A
C6P53_RS07730	COG2205	protein histidine kinase activity
C6P53_RS07735	COG0745	RESPONSE REGULATOR receiver
C6P53_RS07745	COG3609	addiction module antidote protein, CC2985 family
C6P53_RS07755	COG0826	peptidase U32
C6P53_RS07905	COG4695	Portal protein
C6P53_RS07955	COG4974	Belongs to the 'phage' integrase family
C6P53_RS07980	COG1063	alcohol dehydrogenase
C6P53_RS07985	COG3775	system Galactitol-specific IIC component
C6P53_RS07990	COG3414	Phosphotransferase system galactitol-specific IIB component
C6P53_RS07995	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6P53_RS08015	COG2211	Major facilitator Superfamily
C6P53_RS08020	COG1397	ADP-ribosylglycohydrolase
C6P53_RS08025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6P53_RS08030	COG2188	Transcriptional regulator
C6P53_RS08035	COG3757	hydrolase, family 25
C6P53_RS08040	COG0351	phosphomethylpyrimidine kinase
C6P53_RS08055	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
C6P53_RS08060	COG5455	response to cobalt ion
C6P53_RS08065	COG3539	Fimbrial protein
C6P53_RS08075	COG3121	Chaperone
C6P53_RS08080	COG3539	Fimbrial protein
C6P53_RS08090	COG0489	protein tyrosine kinase activity
C6P53_RS08105	COG3831	ATPase activity
C6P53_RS08115	COG0714	Associated with various cellular activities
C6P53_RS08125	COG3552	Protein containing von Willebrand factor type A (VWA) domain
C6P53_RS08130	COG4715	Zinc finger, swim domain protein
C6P53_RS08135	COG4808	Protein conserved in bacteria
C6P53_RS08140	COG4807	Protein conserved in bacteria
C6P53_RS08145	COG3279	Response regulator of the LytR AlgR family
C6P53_RS08155	COG0789	Transcriptional regulator
C6P53_RS08165	COG1174	glycine betaine transport
C6P53_RS08170	COG1125	glycine betaine transport
C6P53_RS08175	COG1174	glycine betaine transport
C6P53_RS08185	COG1472	Belongs to the glycosyl hydrolase 3 family
C6P53_RS08190	COG0277	FAD linked oxidase domain protein
C6P53_RS08195	COG1686	Belongs to the peptidase S11 family
C6P53_RS08205	COG0586	Pfam SNARE associated Golgi protein
C6P53_RS08210	COG1028	Short-chain dehydrogenase reductase Sdr
C6P53_RS08245	COG1346	cytolysis
C6P53_RS08255	COG2949	membrane
C6P53_RS08265	COG0493	'glutamate synthase
C6P53_RS08275	COG4211	Belongs to the binding-protein-dependent transport system permease family
C6P53_RS08285	COG1879	ABC-type sugar transport system periplasmic component
C6P53_RS08290	COG1609	Transcriptional regulator
C6P53_RS08300	COG2311	Membrane
C6P53_RS08335	COG0833	amino acid
C6P53_RS08350	COG2855	membrane
C6P53_RS08360	COG1522	sequence-specific DNA binding
C6P53_RS08360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6P53_RS08365	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C6P53_RS08375	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C6P53_RS08380	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C6P53_RS08400	COG1105	Belongs to the carbohydrate kinase PfkB family
C6P53_RS08410	COG2814	Major facilitator Superfamily
C6P53_RS08425	COG0246	Mannitol dehydrogenase
C6P53_RS08430	COG0523	cobalamin synthesis protein
C6P53_RS08435	COG0671	phosphoesterase, PA-phosphatase related
C6P53_RS08440	COG0791	NLP P60 protein
C6P53_RS08445	COG2200	EAL domain
C6P53_RS08450	COG4166	transmembrane transport
C6P53_RS08455	COG4174	ABC transporter (Permease)
C6P53_RS08460	COG4239	(ABC) transporter, permease
C6P53_RS08490	COG1061	Type III restriction enzyme res subunit
C6P53_RS08520	COG0582	viral genome integration into host DNA
C6P53_RS08595	COG0740	serine-type endopeptidase activity
C6P53_RS08620	COG2197	response regulator
C6P53_RS08630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C6P53_RS08635	COG1138	Cytochrome C-type biogenesis protein
C6P53_RS08645	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C6P53_RS08650	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C6P53_RS08655	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C6P53_RS08665	COG3005	denitrification pathway
C6P53_RS08670	COG3043	anaerobic respiration
C6P53_RS08675	COG0348	domain, Protein
C6P53_RS08680	COG0437	4 iron, 4 sulfur cluster binding
C6P53_RS08690	COG3062	negative regulation of establishment of protein localization
C6P53_RS08695	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6P53_RS08695	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6P53_RS08715	COG4615	Cyclic peptide transporter
C6P53_RS08720	COG3145	DNA-N1-methyladenine dioxygenase activity
C6P53_RS08730	COG1477	protein flavinylation
C6P53_RS08750	COG2198	Histidine kinase
C6P53_RS08750	COG0642	Histidine kinase
C6P53_RS08755	COG2197	response regulator
C6P53_RS08780	COG3234	Protein of unknown function (DUF1175)
C6P53_RS08785	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
C6P53_RS08790	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C6P53_RS08800	COG3468	outer membrane autotransporter barrel domain protein
C6P53_RS08810	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C6P53_RS08820	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C6P53_RS08825	COG3642	lipopolysaccharide core region biosynthetic process
C6P53_RS08830	COG0583	DNA-binding transcription factor activity
C6P53_RS08835	COG0584	glycerophosphoryl diester phosphodiesterase
C6P53_RS08840	COG2271	Major facilitator Superfamily
C6P53_RS08850	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C6P53_RS08860	COG0247	lactate metabolic process
C6P53_RS08865	COG5464	transposase or invertase
C6P53_RS08935	COG0318	PFAM AMP-dependent synthetase and ligase
C6P53_RS08960	COG1169	isochorismate synthase
C6P53_RS08965	COG4575	ribosome binding
C6P53_RS08970	COG2153	protein acetylation
C6P53_RS09000	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C6P53_RS09005	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C6P53_RS09015	COG0839	Belongs to the complex I subunit 6 family
C6P53_RS09035	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
C6P53_RS09060	COG0583	DNA-binding transcription factor activity
C6P53_RS09070	COG0436	Aminotransferase
C6P53_RS09080	COG0471	metal ion transport
C6P53_RS09080	COG0490	domain, Protein
C6P53_RS09085	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C6P53_RS09100	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C6P53_RS09105	COG0857	belongs to the CobB CobQ family
C6P53_RS09105	COG0280	phosphate acetyltransferase
C6P53_RS09110	COG1288	antiporter activity
C6P53_RS09115	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
C6P53_RS09120	COG0622	Phosphoesterase
C6P53_RS09135	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C6P53_RS09140	COG1090	epimerase
C6P53_RS09150	COG4598	ABC transporter
C6P53_RS09160	COG4215	(ABC) transporter
C6P53_RS09175	COG0163	prenyltransferase activity
C6P53_RS09185	COG1286	toxin biosynthetic process
C6P53_RS09190	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
C6P53_RS09195	COG0285	dihydrofolate synthase activity
C6P53_RS09205	COG0586	Pfam SNARE associated Golgi protein
C6P53_RS09215	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C6P53_RS09240	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C6P53_RS09265	COG3101	peptidyl-lysine hydroxylation
C6P53_RS09270	COG0730	response to heat
C6P53_RS09300	COG3539	Fimbrial protein
C6P53_RS09305	COG3539	Fimbrial protein
C6P53_RS09310	COG3539	Fimbrial protein
C6P53_RS09315	COG3121	Chaperone
C6P53_RS09325	COG3539	Fimbrial protein
C6P53_RS09345	COG3691	Protein conserved in bacteria
C6P53_RS09355	COG2067	long-chain fatty acid transport protein
C6P53_RS09370	COG2853	Lipoprotein
C6P53_RS09380	COG2116	formate transmembrane transporter activity
C6P53_RS09390	COG0582	viral genome integration into host DNA
C6P53_RS09490	COG1783	phage Terminase large subunit
C6P53_RS09650	COG4712	double-strand break repair protein
C6P53_RS09755	COG1566	PFAM secretion protein HlyD family protein
C6P53_RS09760	COG2197	response regulator
C6P53_RS09780	COG0028	Belongs to the TPP enzyme family
C6P53_RS09820	COG0436	Aminotransferase
C6P53_RS09825	COG3275	phosphorelay sensor kinase activity
C6P53_RS09830	COG3279	Response regulator of the LytR AlgR family
C6P53_RS09845	COG1363	Peptidase, m42
C6P53_RS09850	COG0006	proline dipeptidase activity
C6P53_RS09855	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6P53_RS09860	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6P53_RS09885	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C6P53_RS09905	COG3415	Transposase
C6P53_RS09910	COG3415	Transposase
C6P53_RS09950	COG0385	Bile acid
C6P53_RS09955	COG3530	Putative quorum-sensing-regulated virulence factor
C6P53_RS09980	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6P53_RS09985	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C6P53_RS10005	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C6P53_RS10010	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C6P53_RS10015	COG4208	sulfate ABC transporter
C6P53_RS10020	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
C6P53_RS10025	COG4150	thiosulfate binding
C6P53_RS10050	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C6P53_RS10055	COG2837	iron assimilation
C6P53_RS10075	COG0860	N-Acetylmuramoyl-L-alanine amidase
C6P53_RS10090	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
C6P53_RS10095	COG4816	utilization protein
C6P53_RS10105	COG4303	Ethanolamine ammonia lyase large subunit
C6P53_RS10110	COG4819	ethanolamine utilization protein
C6P53_RS10115	COG3192	ethanolamine utilization protein
C6P53_RS10120	COG1454	alcohol dehydrogenase
C6P53_RS10130	COG1012	belongs to the aldehyde dehydrogenase family
C6P53_RS10135	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
C6P53_RS10140	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
C6P53_RS10145	COG0280	phosphate acetyltransferase
C6P53_RS10150	COG4812	Cobalamin adenosyltransferase
C6P53_RS10155	COG4766	ethanolamine catabolic process
C6P53_RS10160	COG4917	ethanolamine utilization protein
C6P53_RS10165	COG4810	utilization protein
C6P53_RS10175	COG0280	phosphate acetyltransferase
C6P53_RS10175	COG0281	malic enzyme
C6P53_RS10180	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C6P53_RS10185	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C6P53_RS10190	COG5342	invasion associated locus B
C6P53_RS10200	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6P53_RS10200	COG0493	'glutamate synthase
C6P53_RS10210	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C6P53_RS10225	COG1393	Belongs to the ArsC family
C6P53_RS10240	COG0400	carboxylic ester hydrolase activity
C6P53_RS10245	COG1444	tRNA N-acetyltransferase activity
C6P53_RS10285	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C6P53_RS10290	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6P53_RS10295	COG0651	ATP synthesis coupled electron transport
C6P53_RS10305	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C6P53_RS10320	COG0651	ATP synthesis coupled electron transport
C6P53_RS10325	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
C6P53_RS10325	COG3261	NADH dehydrogenase
C6P53_RS10330	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C6P53_RS10335	COG3260	NADH ubiquinone oxidoreductase 20
C6P53_RS10350	COG2116	formate transmembrane transporter activity
C6P53_RS10355	COG0628	permease
C6P53_RS10365	COG1393	Belongs to the ArsC family
C6P53_RS10375	COG2233	PERMEase
C6P53_RS10395	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C6P53_RS10400	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
C6P53_RS10405	COG0248	Ppx GppA phosphatase
C6P53_RS10430	COG3133	Outer membrane lipoprotein
C6P53_RS10455	COG1645	bacterial-type flagellum-dependent swarming motility
C6P53_RS10470	COG2976	Protein conserved in bacteria
C6P53_RS10505	COG4953	penicillin-binding protein 1C
C6P53_RS10510	COG2373	Large extracellular alpha-helical protein
C6P53_RS10515	COG2897	thiosulfate sulfurtransferase activity
C6P53_RS10530	COG2975	iron-sulfur cluster assembly
C6P53_RS10535	COG0633	Ferredoxin
C6P53_RS10555	COG0822	iron-sulfur transferase activity
C6P53_RS10575	COG0483	inositol monophosphate 1-phosphatase activity
C6P53_RS10595	COG0583	DNA-binding transcription factor activity
C6P53_RS10600	COG4638	Rieske (2fe-2S)
C6P53_RS10625	COG2259	Doxx family
C6P53_RS10630	COG2017	converts alpha-aldose to the beta-anomer
C6P53_RS10635	COG1063	alcohol dehydrogenase
C6P53_RS10640	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6P53_RS10655	COG1879	ABC-type sugar transport system periplasmic component
C6P53_RS10660	COG0457	Tetratricopeptide repeat
C6P53_RS10665	COG1940	carbohydrate kinase activity
C6P53_RS10680	COG0347	Belongs to the P(II) protein family
C6P53_RS10685	COG2204	response regulator
C6P53_RS10690	COG3170	Tfp pilus assembly protein FimV
C6P53_RS10720	COG0560	Phosphoserine phosphatase
C6P53_RS10730	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6P53_RS10755	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
C6P53_RS10795	COG3026	antisigma factor binding
C6P53_RS10800	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
C6P53_RS10815	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C6P53_RS10820	COG0513	Belongs to the DEAD box helicase family
C6P53_RS10825	COG0583	DNA-binding transcription factor activity
C6P53_RS10845	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C6P53_RS10855	COG3118	belongs to the thioredoxin family
C6P53_RS10865	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C6P53_RS10865	COG1042	CoA-binding domain protein
C6P53_RS10865	COG0045	succinate-CoA ligase (ADP-forming) activity
C6P53_RS10875	COG5544	Lipoprotein
C6P53_RS10910	COG0542	response to heat
C6P53_RS10915	COG1496	oxidoreductase activity
C6P53_RS10920	COG0564	pseudouridine synthase activity
C6P53_RS10925	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C6P53_RS10935	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C6P53_RS10955	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C6P53_RS10970	COG2199	diguanylate cyclase activity
C6P53_RS10975	COG2885	chlorophyll binding
C6P53_RS11000	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C6P53_RS11005	COG4137	Cytochrome C assembly protein
C6P53_RS11010	COG4536	flavin adenine dinucleotide binding
C6P53_RS11030	COG0497	DNA recombination
C6P53_RS11035	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C6P53_RS11045	COG2867	negative regulation of translational initiation
C6P53_RS11060	COG0582	viral genome integration into host DNA
C6P53_RS11095	COG0579	oxidoreductase
C6P53_RS11100	COG1012	belongs to the aldehyde dehydrogenase family
C6P53_RS11105	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C6P53_RS11110	COG1113	amino acid transport
C6P53_RS11115	COG1802	Transcriptional regulator
C6P53_RS11120	COG1652	LysM domain
C6P53_RS11130	COG0640	Transcriptional regulator
C6P53_RS11135	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C6P53_RS11140	COG2916	Histone family protein nucleoid-structuring protein H-NS
C6P53_RS11155	COG4575	ribosome binding
C6P53_RS11160	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C6P53_RS11175	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C6P53_RS11180	COG4175	Glycine betaine
C6P53_RS11185	COG4176	ABC-type proline glycine betaine transport system permease component
C6P53_RS11190	COG2113	Glycine betaine
C6P53_RS11195	COG2814	Major facilitator Superfamily
C6P53_RS11215	COG1566	PFAM secretion protein HlyD family protein
C6P53_RS11220	COG2814	Major facilitator Superfamily
C6P53_RS11235	COG1238	metal cluster binding
C6P53_RS11240	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C6P53_RS11270	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
C6P53_RS11290	COG1546	Belongs to the CinA family
C6P53_RS11295	COG2951	lytic endotransglycosylase activity
C6P53_RS11305	COG3732	PTS system glucitol sorbitol-specific
C6P53_RS11320	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6P53_RS11325	COG1349	DNA-binding transcription factor activity
C6P53_RS11330	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C6P53_RS11330	COG0517	IMP dehydrogenase activity
C6P53_RS11350	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
C6P53_RS11355	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6P53_RS11360	COG1609	Transcriptional regulator
C6P53_RS11370	COG2723	6-phospho-beta-galactosidase activity
C6P53_RS11375	COG5499	transcription regulator containing HTH domain
C6P53_RS11395	COG3260	NADH ubiquinone oxidoreductase 20
C6P53_RS11400	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C6P53_RS11405	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
C6P53_RS11405	COG3261	NADH dehydrogenase
C6P53_RS11410	COG0650	Formate hydrogenlyase subunit 4
C6P53_RS11415	COG0651	ATP synthesis coupled electron transport
C6P53_RS11420	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6P53_RS11430	COG0375	protein maturation
C6P53_RS11440	COG0298	carbon dioxide binding
C6P53_RS11445	COG0409	Hydrogenase expression formation protein
C6P53_RS11450	COG0309	Hydrogenase expression formation protein (HypE)
C6P53_RS11455	COG3604	Transcriptional regulator
C6P53_RS11475	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C6P53_RS11480	COG1349	DNA-binding transcription factor activity
C6P53_RS11495	COG0235	Class ii aldolase
C6P53_RS11500	COG3622	Belongs to the hyi family
C6P53_RS11505	COG2610	gluconate transmembrane transporter activity
C6P53_RS11530	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C6P53_RS11535	COG4942	peptidase
C6P53_RS11535	COG1388	LysM domain
C6P53_RS11595	COG2234	aminopeptidase activity
C6P53_RS11600	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6P53_RS11605	COG1518	maintenance of DNA repeat elements
C6P53_RS11620	COG1857	crispr-associated protein
C6P53_RS11640	COG1203	CRISPR-associated helicase, Cas3
C6P53_RS11670	COG0720	synthase
C6P53_RS11675	COG0644	oxidoreductase
C6P53_RS11680	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C6P53_RS11685	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
C6P53_RS11695	COG2086	electron transfer activity
C6P53_RS11700	COG0477	Major facilitator Superfamily
C6P53_RS11720	COG1070	Carbohydrate kinase
C6P53_RS11750	COG3956	TIGRFAM MazG family protein
C6P53_RS11755	COG2337	Toxic component of a toxin-antitoxin (TA) module
C6P53_RS11760	COG2336	PFAM SpoVT AbrB
C6P53_RS11765	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C6P53_RS11775	COG2205	protein histidine kinase activity
C6P53_RS11775	COG3437	response regulator, receiver
C6P53_RS11775	COG3850	Histidine kinase
C6P53_RS11775	COG4999	Histidine kinase
C6P53_RS11780	COG4948	Mandelate Racemase Muconate Lactonizing
C6P53_RS11785	COG4948	Mandelate Racemase Muconate Lactonizing
C6P53_RS11790	COG2271	Major facilitator Superfamily
C6P53_RS11795	COG0716	FMN binding
C6P53_RS11800	COG0564	pseudouridine synthase activity
C6P53_RS11805	COG3098	single-species biofilm formation
C6P53_RS11820	COG1611	Belongs to the LOG family
C6P53_RS11830	COG0814	amino acid
C6P53_RS11835	COG1760	l-serine dehydratase
C6P53_RS11845	COG1454	alcohol dehydrogenase
C6P53_RS11860	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C6P53_RS11865	COG1609	Transcriptional regulator
C6P53_RS11870	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6P53_RS11875	COG1129	ABC transporter
C6P53_RS11905	COG2363	Small membrane protein
C6P53_RS11910	COG0583	DNA-binding transcription factor activity
C6P53_RS11920	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C6P53_RS11925	COG2166	iron-sulfur cluster assembly
C6P53_RS11930	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C6P53_RS11960	COG0860	N-Acetylmuramoyl-L-alanine amidase
C6P53_RS11965	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C6P53_RS11965	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C6P53_RS11970	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C6P53_RS11990	COG4967	type IV pilus modification protein PilV
C6P53_RS12000	COG4795	General secretion pathway protein
C6P53_RS12005	COG2165	general secretion pathway protein
C6P53_RS12025	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
C6P53_RS12050	COG0667	Aldo Keto reductase
C6P53_RS12065	COG1609	Transcriptional regulator
C6P53_RS12080	COG1794	racemase activity, acting on amino acids and derivatives
C6P53_RS12085	COG2814	Major facilitator Superfamily
C6P53_RS12090	COG1028	Short-chain dehydrogenase reductase Sdr
C6P53_RS12105	COG0814	amino acid
C6P53_RS12110	COG2771	luxR family
C6P53_RS12115	COG3710	Transcriptional regulator
C6P53_RS12140	COG0457	Tetratricopeptide repeat
C6P53_RS12160	COG2197	response regulator
C6P53_RS12165	COG2197	response regulator
C6P53_RS12260	COG3387	PFAM Glycoside hydrolase 15-related
C6P53_RS12290	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C6P53_RS12295	COG2080	2 iron, 2 sulfur cluster binding
C6P53_RS12305	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C6P53_RS12315	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C6P53_RS12325	COG0549	Belongs to the carbamate kinase family
C6P53_RS12330	COG3608	succinylglutamate desuccinylase aspartoacylase
C6P53_RS12330	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C6P53_RS12340	COG2068	MobA-Related Protein
C6P53_RS12350	COG0402	S-adenosylhomocysteine deaminase activity
C6P53_RS12370	COG0402	S-adenosylhomocysteine deaminase activity
C6P53_RS12375	COG2252	PERMEase
C6P53_RS12380	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6P53_RS12395	COG2233	PERMEase
C6P53_RS12430	COG4974	Belongs to the 'phage' integrase family
C6P53_RS12445	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
C6P53_RS12455	COG1272	protein, Hemolysin III
C6P53_RS12465	COG2723	6-phospho-beta-galactosidase activity
C6P53_RS12470	COG1028	Short-chain dehydrogenase reductase Sdr
C6P53_RS12495	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C6P53_RS12500	COG0006	proline dipeptidase activity
C6P53_RS12545	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C6P53_RS12565	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C6P53_RS12565	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C6P53_RS12580	COG0427	acetyl-CoA hydrolase
C6P53_RS12600	COG0668	transmembrane transport
C6P53_RS12645	COG1122	ATPase activity
C6P53_RS12650	COG1122	ATPase activity
C6P53_RS12665	COG1494	fructose-1,6-bisphosphatase
C6P53_RS12675	COG2213	PTS system mannitol-specific
C6P53_RS12680	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6P53_RS12690	COG0501	Belongs to the peptidase M48B family
C6P53_RS12705	COG3716	PTS system mannose fructose sorbose family IID component
C6P53_RS12710	COG3715	PTS system
C6P53_RS12715	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6P53_RS12715	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6P53_RS12740	COG1166	arginine decarboxylase activity
C6P53_RS12765	COG2814	Major facilitator Superfamily
C6P53_RS12775	COG2356	endonuclease I
C6P53_RS12780	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C6P53_RS12785	COG0189	ligase activity
C6P53_RS12800	COG2805	Type II/IV secretion system protein
C6P53_RS12805	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C6P53_RS12810	COG0762	integral membrane protein
C6P53_RS12825	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C6P53_RS12830	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C6P53_RS12835	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
C6P53_RS12850	COG0252	asparaginase activity
C6P53_RS12860	COG3171	Protein conserved in bacteria
C6P53_RS12890	COG2211	Major facilitator Superfamily
C6P53_RS12895	COG1982	Orn Lys Arg decarboxylase major
C6P53_RS12905	COG1811	Na channel or pump
C6P53_RS12915	COG0582	viral genome integration into host DNA
C6P53_RS12960	COG3436	PFAM IS66 Orf2 family protein
C6P53_RS12965	COG4372	Transposase
C6P53_RS13005	COG2207	Transcriptional regulator
C6P53_RS13190	COG5295	Hep Hag repeat protein
C6P53_RS13220	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6P53_RS13230	COG3037	sugar-specific permease SgaT UlaA
C6P53_RS13420	COG3436	PFAM IS66 Orf2 family protein
C6P53_RS13425	COG4372	Transposase
C6P53_RS13455	COG3468	outer membrane autotransporter barrel domain protein
C6P53_RS13495	COG2003	Belongs to the UPF0758 family
C6P53_RS13530	COG3609	addiction module antidote protein, CC2985 family
C6P53_RS13545	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
C6P53_RS13575	COG2165	general secretion pathway protein
C6P53_RS13580	COG1459	type II secretion system
C6P53_RS13630	COG3193	protein, possibly involved in utilization of glycolate and propanediol
C6P53_RS13635	COG0247	lactate metabolic process
C6P53_RS13640	COG0277	FAD linked oxidase domain protein
C6P53_RS13645	COG0277	FAD linked oxidase domain protein
C6P53_RS13650	COG2186	Transcriptional regulator
C6P53_RS13675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C6P53_RS13680	COG0156	8-amino-7-oxononanoate synthase activity
C6P53_RS13690	COG0795	lipopolysaccharide-transporting ATPase activity
C6P53_RS13695	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
C6P53_RS13705	COG2244	polysaccharide biosynthetic process
C6P53_RS13710	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C6P53_RS13715	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C6P53_RS13720	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C6P53_RS13730	COG0754	glutathionylspermidine amidase activity
C6P53_RS13735	COG0625	glutathione transferase activity
C6P53_RS13750	COG0298	carbon dioxide binding
C6P53_RS13770	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
C6P53_RS13775	COG5557	Pfam Polysulphide reductase, NrfD
C6P53_RS13785	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
C6P53_RS13805	COG0667	Aldo Keto reductase
C6P53_RS13820	COG0848	biopolymer transport protein
C6P53_RS13825	COG0811	peptide transport
C6P53_RS13835	COG0626	cystathionine gamma-synthase activity
C6P53_RS13840	COG0586	Pfam SNARE associated Golgi protein
C6P53_RS13845	COG2207	Transcriptional regulator
C6P53_RS13855	COG0656	L-ascorbic acid biosynthetic process
C6P53_RS13865	COG4238	major outer membrane lipoprotein
C6P53_RS13875	COG2132	Multicopper oxidase
C6P53_RS13880	COG0204	Acyl-transferase
C6P53_RS13885	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C6P53_RS13895	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
C6P53_RS13900	COG3111	PFAM Bacterial OB fold (BOF) protein
C6P53_RS13905	COG0745	RESPONSE REGULATOR receiver
C6P53_RS13910	COG0642	Histidine kinase
C6P53_RS13920	COG2249	NAD(P)H dehydrogenase (quinone) activity
C6P53_RS13925	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C6P53_RS13930	COG0187	DNA topoisomerase II activity
C6P53_RS13945	COG3151	Protein conserved in bacteria
C6P53_RS13950	COG0494	nUDIX hydrolase
C6P53_RS13970	COG0754	glutathionylspermidine amidase activity
C6P53_RS13975	COG3384	dioxygenase
C6P53_RS14005	COG3188	usher protein
C6P53_RS14010	COG3121	Chaperone
C6P53_RS14015	COG3539	Fimbrial protein
C6P53_RS14075	COG4991	sh3 domain protein
C6P53_RS14090	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C6P53_RS14110	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C6P53_RS14115	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C6P53_RS14135	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C6P53_RS14140	COG0358	DNA primase activity
C6P53_RS14150	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C6P53_RS14165	COG2375	cellular response to nickel ion
C6P53_RS14175	COG1695	Transcriptional regulator
C6P53_RS14180	COG0840	transmembrane signaling receptor activity
C6P53_RS14195	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C6P53_RS14205	COG1609	Transcriptional regulator
C6P53_RS14210	COG3250	beta-galactosidase activity
C6P53_RS14215	COG2731	YhcH YjgK YiaL family protein
C6P53_RS14220	COG0531	amino acid
C6P53_RS14230	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
C6P53_RS14230	COG3408	Glycogen debranching enzyme
C6P53_RS14235	COG0446	pyridine nucleotide-disulphide oxidoreductase
C6P53_RS14235	COG1902	pentaerythritol trinitrate reductase activity
C6P53_RS14240	COG5499	transcription regulator containing HTH domain
C6P53_RS14245	COG4680	protein conserved in bacteria
C6P53_RS14255	COG1451	nucleotide metabolic process
C6P53_RS14260	COG2949	membrane
C6P53_RS14265	COG0673	inositol 2-dehydrogenase activity
C6P53_RS14270	COG0861	Integral membrane protein TerC family
C6P53_RS14275	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
C6P53_RS14285	COG2721	sulfolactate sulfo-lyase activity
C6P53_RS14295	COG2271	Major facilitator Superfamily
C6P53_RS14330	COG2186	Transcriptional regulator
C6P53_RS14345	COG1422	Protein of unknown function (DUF1090)
C6P53_RS14350	COG4575	ribosome binding
C6P53_RS14355	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
C6P53_RS14365	COG2259	Doxx family
C6P53_RS14370	COG0435	Glutathione S-transferase
C6P53_RS14375	COG3152	Membrane
C6P53_RS14390	COG0583	DNA-binding transcription factor activity
C6P53_RS14395	COG1741	Belongs to the pirin family
C6P53_RS14410	COG0814	amino acid
C6P53_RS14420	COG1760	l-serine dehydratase
C6P53_RS14425	COG0251	oxidation-reduction process
C6P53_RS14430	COG1882	Formate acetyltransferase
C6P53_RS14445	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C6P53_RS14455	COG0583	DNA-binding transcription factor activity
C6P53_RS14485	COG1929	Belongs to the glycerate kinase type-1 family
C6P53_RS14510	COG2002	toxin-antitoxin pair type II binding
C6P53_RS14520	COG1349	DNA-binding transcription factor activity
C6P53_RS14535	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6P53_RS14545	COG3716	PTS system mannose fructose sorbose family IID component
C6P53_RS14550	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6P53_RS14555	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C6P53_RS14560	COG2222	sugar isomerase
C6P53_RS14570	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6P53_RS14575	COG3715	PTS system
C6P53_RS14580	COG3716	PTS system mannose fructose sorbose family IID component
C6P53_RS14585	COG0363	glucosamine-6-phosphate deaminase activity
C6P53_RS14590	COG3539	Fimbrial protein
C6P53_RS14595	COG3121	Chaperone
C6P53_RS14600	COG3188	usher protein
C6P53_RS14605	COG3539	Fimbrial protein
C6P53_RS14610	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C6P53_RS14635	COG0701	Predicted permease
C6P53_RS14640	COG0702	epimerase
C6P53_RS14645	COG0693	protein deglycase activity
C6P53_RS14660	COG3153	acetyltransferase
C6P53_RS14670	COG0826	peptidase U32
C6P53_RS14675	COG0826	peptidase U32
C6P53_RS14680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C6P53_RS14685	COG0814	amino acid
C6P53_RS14690	COG0513	Belongs to the DEAD box helicase family
C6P53_RS14735	COG0195	Participates in both transcription termination and antitermination
C6P53_RS14765	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C6P53_RS14775	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C6P53_RS14780	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C6P53_RS14790	COG1534	Rna-binding protein
C6P53_RS14795	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C6P53_RS14810	COG0697	spore germination
C6P53_RS14825	COG0142	geranyltranstransferase activity
C6P53_RS14840	COG5007	Belongs to the BolA IbaG family
C6P53_RS14845	COG3113	response to antibiotic
C6P53_RS14850	COG2854	intermembrane phospholipid transfer
C6P53_RS14855	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C6P53_RS14860	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C6P53_RS14865	COG1127	ABC transporter
C6P53_RS14875	COG0517	IMP dehydrogenase activity
C6P53_RS14875	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C6P53_RS14880	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
C6P53_RS14885	COG3117	lipopolysaccharide transmembrane transporter activity
C6P53_RS14895	COG1137	ATPase activity
C6P53_RS14900	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C6P53_RS14905	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C6P53_RS14920	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6P53_RS14925	COG0515	serine threonine protein kinase
C6P53_RS14935	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
C6P53_RS14960	COG0069	glutamate synthase activity
C6P53_RS14960	COG0067	glutamate synthase
C6P53_RS14960	COG0070	glutamate synthase
C6P53_RS14965	COG0493	'glutamate synthase
C6P53_RS14970	COG4804	nuclease activity
C6P53_RS14980	COG2731	YhcH YjgK YiaL family protein
C6P53_RS15020	COG2969	positive regulation of protein catabolic process
C6P53_RS15025	COG0625	glutathione transferase activity
C6P53_RS15055	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
C6P53_RS15060	COG3105	Protein conserved in bacteria
C6P53_RS15070	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C6P53_RS15090	COG2732	(Barnase) inhibitor
C6P53_RS15120	COG3164	Protein of unknown function
C6P53_RS15125	COG1530	ribonuclease E activity
C6P53_RS15135	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C6P53_RS15145	COG1077	Cell shape determining protein MreB Mrl
C6P53_RS15165	COG0604	alcohol dehydrogenase
C6P53_RS15175	COG0511	ligase activity, forming carbon-carbon bonds
C6P53_RS15180	COG0439	Biotin carboxylase
C6P53_RS15185	COG3924	membrane
C6P53_RS15190	COG4145	pantothenate transmembrane transporter activity
C6P53_RS15200	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C6P53_RS15210	COG2189	Belongs to the N(4) N(6)-methyltransferase family
C6P53_RS15235	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C6P53_RS15250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6P53_RS15255	COG4597	amino acid ABC transporter
C6P53_RS15305	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C6P53_RS15325	COG0551	DNA topoisomerase type I activity
C6P53_RS15355	COG0569	domain protein
C6P53_RS15365	COG3036	rescue of stalled ribosome
C6P53_RS15370	COG0789	Transcriptional regulator
C6P53_RS15500	COG0089	rRNA binding
C6P53_RS15580	COG2964	Protein conserved in bacteria
C6P53_RS15585	COG0545	Peptidyl-prolyl cis-trans isomerase
C6P53_RS15595	COG1047	Peptidyl-prolyl cis-trans
C6P53_RS15600	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
C6P53_RS15620	COG0488	(ABC) transporter
C6P53_RS15635	COG3954	Phosphoribulokinase
C6P53_RS15640	COG1765	OsmC-like protein
C6P53_RS15650	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C6P53_RS15660	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C6P53_RS15665	COG0512	Glutamine amidotransferase of anthranilate synthase
C6P53_RS15670	COG2184	nucleotidyltransferase activity
C6P53_RS15680	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C6P53_RS15690	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C6P53_RS15695	COG2146	nitrite reductase [NAD(P)H] activity
C6P53_RS15700	COG2116	formate transmembrane transporter activity
C6P53_RS15715	COG0531	amino acid
C6P53_RS15720	COG2222	sugar isomerase
C6P53_RS15740	COG2188	Transcriptional regulator
C6P53_RS15745	COG0626	cystathionine gamma-synthase activity
C6P53_RS15760	COG1735	metal-dependent hydrolase with the TIM-barrel fold
C6P53_RS15770	COG3457	Alanine racemase
C6P53_RS15780	COG2188	Transcriptional regulator
C6P53_RS15785	COG0180	Tryptophanyl-tRNA synthetase
C6P53_RS15795	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C6P53_RS15800	COG0338	D12 class N6 adenine-specific DNA methyltransferase
C6P53_RS15805	COG3266	domain, Protein
C6P53_RS15840	COG3166	PFAM Fimbrial assembly family protein
C6P53_RS15845	COG4972	Pilus assembly protein
C6P53_RS15850	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
C6P53_RS15855	COG0494	nUDIX hydrolase
C6P53_RS15865	COG1011	Hydrolase
C6P53_RS15870	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C6P53_RS15910	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C6P53_RS15915	COG2183	response to ionizing radiation
C6P53_RS15925	COG1918	ferrous iron import across plasma membrane
C6P53_RS15930	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
C6P53_RS15945	COG5464	transposase or invertase
C6P53_RS15955	COG1040	competence protein
C6P53_RS15965	COG2610	gluconate transmembrane transporter activity
C6P53_RS15990	COG1690	Belongs to the RtcB family
C6P53_RS15995	COG4650	regulator
C6P53_RS16000	COG1349	DNA-binding transcription factor activity
C6P53_RS16035	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C6P53_RS16070	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C6P53_RS16075	COG2095	MarC family integral membrane protein
C6P53_RS16085	COG3265	gluconokinase activity
C6P53_RS16090	COG1609	Transcriptional regulator
C6P53_RS16095	COG1741	Belongs to the pirin family
C6P53_RS16100	COG0673	inositol 2-dehydrogenase activity
C6P53_RS16110	COG1247	-acetyltransferase
C6P53_RS16135	COG0405	Gamma-glutamyltransferase
C6P53_RS16145	COG0584	glycerophosphoryl diester phosphodiesterase
C6P53_RS16155	COG0395	ABC-type sugar transport system, permease component
C6P53_RS16160	COG1175	transmembrane transport
C6P53_RS16165	COG1653	transport
C6P53_RS16170	COG0410	ABC transporter
C6P53_RS16175	COG0411	ABC transporter
C6P53_RS16180	COG4177	L-phenylalanine transmembrane transporter activity
C6P53_RS16195	COG0456	acetyltransferase
C6P53_RS16210	COG0683	leucine binding
C6P53_RS16220	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C6P53_RS16225	COG2177	Part of the ABC transporter FtsEX involved in
C6P53_RS16230	COG2884	Cell division ATP-binding protein ftsE
C6P53_RS16235	COG0552	protein localization to endoplasmic reticulum
C6P53_RS16240	COG0742	ribosomal rna small subunit methyltransferase
C6P53_RS16245	COG3776	membrane
C6P53_RS16255	COG3714	YhhN family
C6P53_RS16270	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C6P53_RS16285	COG0628	permease
C6P53_RS16295	COG0747	negative chemotaxis
C6P53_RS16300	COG0601	transmembrane transport
C6P53_RS16305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C6P53_RS16310	COG0444	Belongs to the ABC transporter superfamily
C6P53_RS16315	COG1124	(ABC) transporter
C6P53_RS16335	COG0842	Transport permease protein
C6P53_RS16340	COG0842	Transport permease protein
C6P53_RS16340	COG1129	ABC transporter
C6P53_RS16345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6P53_RS16375	COG0306	phosphate transporter
C6P53_RS16405	COG0339	signal peptide processing
C6P53_RS16415	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C6P53_RS16430	COG0640	Transcriptional regulator
C6P53_RS16435	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C6P53_RS16460	COG3065	identical protein binding
C6P53_RS16475	COG1285	pathogenesis
C6P53_RS16490	COG3247	response to pH
C6P53_RS16495	COG2771	luxR family
C6P53_RS16505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6P53_RS16520	COG2207	Transcriptional regulator
C6P53_RS16530	COG0076	glutamate decarboxylase activity
C6P53_RS16545	COG2197	response regulator
C6P53_RS16550	COG0583	DNA-binding transcription factor activity
C6P53_RS16555	COG1295	ribonuclease BN
C6P53_RS16610	COG0457	Tetratricopeptide repeat
C6P53_RS16610	COG3118	belongs to the thioredoxin family
C6P53_RS16615	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
C6P53_RS16625	COG1215	transferase activity, transferring glycosyl groups
C6P53_RS16650	COG2194	sulfuric ester hydrolase activity
C6P53_RS16680	COG0814	amino acid
C6P53_RS16685	COG4608	Belongs to the ABC transporter superfamily
C6P53_RS16690	COG0444	Belongs to the ABC transporter superfamily
C6P53_RS16695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C6P53_RS16700	COG0601	transmembrane transport
C6P53_RS16710	COG0747	negative chemotaxis
C6P53_RS16735	COG2223	nitrite transmembrane transporter activity
C6P53_RS16745	COG5571	outer membrane autotransporter
C6P53_RS16750	COG2818	Glycosylase
C6P53_RS16755	COG0456	acetyltransferase
C6P53_RS16765	COG2885	chlorophyll binding
C6P53_RS16780	COG2944	sequence-specific DNA binding
C6P53_RS16785	COG1278	Cold shock
C6P53_RS16810	COG3274	enterobacterial common antigen metabolic process
C6P53_RS16815	COG4682	membrane
C6P53_RS16820	COG4682	membrane
C6P53_RS16825	COG1070	Carbohydrate kinase
C6P53_RS16835	COG4213	ABC transporter substrate-binding protein
C6P53_RS16840	COG1129	ABC transporter
C6P53_RS16845	COG4214	carbohydrate transport
C6P53_RS16850	COG1609	Transcriptional regulator
C6P53_RS16850	COG2207	Transcriptional regulator
C6P53_RS16855	COG2992	FlgJ-related protein
C6P53_RS16860	COG0366	Alpha amylase catalytic
C6P53_RS16865	COG3977	Valine--pyruvate aminotransferase
C6P53_RS16870	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6P53_RS16875	COG1414	Transcriptional regulator
C6P53_RS16885	COG2731	YhcH YjgK YiaL family protein
C6P53_RS16890	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
C6P53_RS16895	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
C6P53_RS16900	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C6P53_RS16910	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
C6P53_RS16920	COG0235	Class ii aldolase
C6P53_RS16930	COG3713	MltA-interacting MipA family protein
C6P53_RS16935	COG0583	DNA-binding transcription factor activity
C6P53_RS16940	COG1566	PFAM secretion protein HlyD family protein
C6P53_RS16955	COG1012	belongs to the aldehyde dehydrogenase family
C6P53_RS16960	COG1454	alcohol dehydrogenase
C6P53_RS16965	COG3276	selenocysteine insertion sequence binding
C6P53_RS16975	COG0625	glutathione transferase activity
C6P53_RS17000	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C6P53_RS17030	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6P53_RS17030	COG2213	PTS system mannitol-specific
C6P53_RS17040	COG3722	fumarate hydratase activity
C6P53_RS17100	COG2186	Transcriptional regulator
C6P53_RS17110	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C6P53_RS17115	COG1045	serine acetyltransferase
C6P53_RS17130	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C6P53_RS17135	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C6P53_RS17150	COG4942	peptidase
C6P53_RS17185	COG0859	PFAM glycosyl transferase family 9
C6P53_RS17190	COG0859	PFAM glycosyl transferase family 9
C6P53_RS17225	COG0438	transferase activity, transferring glycosyl groups
C6P53_RS17230	COG0859	PFAM glycosyl transferase family 9
C6P53_RS17265	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C6P53_RS17295	COG1561	YicC-like family, N-terminal region
C6P53_RS17300	COG3645	SOS response
C6P53_RS17305	COG2860	membrane
C6P53_RS17325	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C6P53_RS17330	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C6P53_RS17340	COG0786	glutamate:sodium symporter activity
C6P53_RS17345	COG2233	PERMEase
C6P53_RS17350	COG2982	Protein involved in outer membrane biogenesis
C6P53_RS17355	COG1501	Belongs to the glycosyl hydrolase 31 family
C6P53_RS17360	COG2211	Major facilitator Superfamily
C6P53_RS17370	COG0582	viral genome integration into host DNA
C6P53_RS17415	COG2207	Transcriptional regulator
C6P53_RS17430	COG4771	TonB-dependent receptor
C6P53_RS17450	COG1609	Transcriptional regulator
C6P53_RS17455	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6P53_RS17465	COG3037	sugar-specific permease SgaT UlaA
C6P53_RS17490	COG2826	transposase and inactivated derivatives, IS30 family
C6P53_RS17755	COG3468	outer membrane autotransporter barrel domain protein
C6P53_RS17790	COG2003	Belongs to the UPF0758 family
C6P53_RS17840	COG0697	spore germination
C6P53_RS17845	COG1464	Belongs to the NlpA lipoprotein family
C6P53_RS17885	COG2271	Major facilitator Superfamily
C6P53_RS17890	COG2271	Major facilitator Superfamily
C6P53_RS17895	COG3851	Histidine kinase
C6P53_RS17900	COG2197	response regulator
C6P53_RS17905	COG0440	acetolactate synthase activity
C6P53_RS17910	COG0028	Belongs to the TPP enzyme family
C6P53_RS17945	COG2814	Major facilitator Superfamily
C6P53_RS17950	COG0641	radical SAM
C6P53_RS17960	COG2149	membrane
C6P53_RS17970	COG3119	arylsulfatase activity
C6P53_RS17975	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C6P53_RS17980	COG2207	Transcriptional regulator
C6P53_RS17995	COG2188	Transcriptional regulator
C6P53_RS18015	COG5645	(Lipo)protein
C6P53_RS18020	COG0823	Involved in the tonB-independent uptake of proteins
C6P53_RS18030	COG2271	Major facilitator Superfamily
C6P53_RS18040	COG0800	Aldolase
C6P53_RS18045	COG3734	2-keto-3-deoxy-galactonokinase
C6P53_RS18050	COG2186	Transcriptional regulator
C6P53_RS18060	COG0561	phosphatase activity
C6P53_RS18080	COG0592	DNA-directed DNA polymerase activity
C6P53_RS18130	COG0814	amino acid
C6P53_RS18150	COG0431	NADPH-dependent FMN reductase
C6P53_RS18160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C6P53_RS18175	COG0363	glucosamine-6-phosphate deaminase activity
C6P53_RS18190	COG2723	6-phospho-beta-galactosidase activity
C6P53_RS18205	COG0704	Plays a role in the regulation of phosphate uptake
C6P53_RS18210	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C6P53_RS18215	COG0581	inorganic phosphate transmembrane transporter activity
C6P53_RS18225	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C6P53_RS18235	COG3188	usher protein
C6P53_RS18250	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C6P53_RS18305	COG3312	ion transport
C6P53_RS18360	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6P53_RS18365	COG1879	ABC-type sugar transport system periplasmic component
C6P53_RS18370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6P53_RS18375	COG1609	Transcriptional regulator
C6P53_RS18380	COG0477	Major facilitator Superfamily
C6P53_RS18385	COG2186	Transcriptional regulator
C6P53_RS18425	COG3085	chromosome segregation
C6P53_RS18455	COG3978	acetolactate synthase activity
C6P53_RS18470	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C6P53_RS18475	COG0583	DNA-binding transcription factor activity
C6P53_RS18485	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C6P53_RS18490	COG3692	DNA binding
C6P53_RS18525	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C6P53_RS18540	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
C6P53_RS18545	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C6P53_RS18560	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C6P53_RS18570	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C6P53_RS18595	COG1113	amino acid transport
C6P53_RS18625	COG3071	HemY protein
C6P53_RS18630	COG2959	enzyme of heme biosynthesis
C6P53_RS18650	COG3072	Adenylate cyclase
C6P53_RS18660	COG5567	small periplasmic lipoprotein
C6P53_RS18670	COG3159	Protein conserved in bacteria
C6P53_RS18680	COG1011	Hydrolase
C6P53_RS18690	COG3698	Phosphodiester glycosidase
C6P53_RS18695	COG0598	Magnesium transport protein CorA
C6P53_RS18725	COG2962	Rard protein
C6P53_RS18730	COG2050	protein possibly involved in aromatic compounds catabolism
C6P53_RS18740	COG0514	ATP-dependent DNA helicase (RecQ)
C6P53_RS18745	COG1280	lysine exporter protein (LysE YggA)
C6P53_RS18750	COG1280	lysine exporter protein (LysE YggA)
C6P53_RS18760	COG0561	phosphatase activity
C6P53_RS18765	COG0697	spore germination
C6P53_RS18780	COG0412	Dienelactone hydrolase
C6P53_RS18785	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
C6P53_RS18790	COG1322	Protein conserved in bacteria
C6P53_RS18800	COG3165	ubiquinone biosynthetic process from chorismate
C6P53_RS18810	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C6P53_RS18815	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C6P53_RS18820	COG0805	protein transport
C6P53_RS18825	COG0084	hydrolase, TatD family'
C6P53_RS18830	COG0250	Participates in transcription elongation, termination and antitermination
C6P53_RS18840	COG0543	2 iron, 2 sulfur cluster binding
C6P53_RS18860	COG1739	Uncharacterized protein family UPF0029
C6P53_RS18870	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
C6P53_RS18900	COG1763	Mo-molybdopterin cofactor biosynthetic process
C6P53_RS18915	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C6P53_RS18920	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C6P53_RS18925	COG5339	Protein conserved in bacteria
C6P53_RS18930	COG0204	Acyl-transferase
C6P53_RS18955	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C6P53_RS18965	COG2204	response regulator
C6P53_RS18985	COG1217	gtp-binding protein TYPA
C6P53_RS19005	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
C6P53_RS19010	COG2211	Major facilitator Superfamily
C6P53_RS19025	COG2017	converts alpha-aldose to the beta-anomer
C6P53_RS19035	COG3684	Belongs to the aldolase LacD family
C6P53_RS19045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6P53_RS19050	COG1349	DNA-binding transcription factor activity
C6P53_RS19055	COG1011	Hydrolase
C6P53_RS19070	COG0456	acetyltransferase
C6P53_RS19080	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
C6P53_RS19095	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C6P53_RS19100	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C6P53_RS19110	COG2864	formate dehydrogenase
C6P53_RS19115	COG0437	4 iron, 4 sulfur cluster binding
C6P53_RS19140	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6P53_RS19140	COG3711	transcriptional antiterminator
C6P53_RS19145	COG1363	Peptidase, m42
C6P53_RS19150	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6P53_RS19150	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6P53_RS19155	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6P53_RS19195	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C6P53_RS19210	COG2258	MOSC domain
C6P53_RS19220	COG0745	RESPONSE REGULATOR receiver
C6P53_RS19245	COG3547	Transposase (IS116 IS110 IS902 family)
C6P53_RS19275	COG3691	Protein conserved in bacteria
C6P53_RS19280	COG0589	response to stress
C6P53_RS19290	COG1494	fructose-1,6-bisphosphatase
C6P53_RS19300	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C6P53_RS19330	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C6P53_RS19335	COG1609	Transcriptional regulator
C6P53_RS19375	COG3547	Transposase (IS116 IS110 IS902 family)
C6P53_RS19390	COG0626	cystathionine gamma-synthase activity
C6P53_RS19410	COG0697	spore germination
C6P53_RS19415	COG3738	Protein conserved in bacteria
C6P53_RS19420	COG0371	Dehydrogenase
C6P53_RS19425	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C6P53_RS19430	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6P53_RS19430	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6P53_RS19430	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C6P53_RS19435	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6P53_RS19440	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6P53_RS19445	COG1882	Formate acetyltransferase
C6P53_RS19450	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C6P53_RS19455	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6P53_RS19480	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C6P53_RS19495	COG0583	DNA-binding transcription factor activity
C6P53_RS19560	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C6P53_RS19565	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
C6P53_RS19565	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
C6P53_RS19610	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C6P53_RS19615	COG0250	Participates in transcription elongation, termination and antitermination
C6P53_RS19670	COG2104	thiamine diphosphate biosynthetic process
C6P53_RS19725	COG3678	ATP-independent chaperone mediated protein folding
C6P53_RS19735	COG4191	Histidine kinase
C6P53_RS19740	COG2204	response regulator
C6P53_RS19745	COG0151	Belongs to the GarS family
C6P53_RS19780	COG0456	acetyltransferase
C6P53_RS19790	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C6P53_RS19795	COG2224	Isocitrate lyase
C6P53_RS19815	COG1414	Transcriptional regulator
C6P53_RS19835	COG1187	pseudouridine synthase activity
C6P53_RS19850	COG3541	Predicted nucleotidyltransferase
C6P53_RS19855	COG0542	response to heat
C6P53_RS19860	COG0527	aspartate kinase activity
C6P53_RS19915	COG3833	ABC-type maltose transport systems, permease component
C6P53_RS19920	COG1175	transmembrane transport
C6P53_RS19925	COG2182	Extracellular solute-binding protein
C6P53_RS19955	COG1357	PFAM Pentapeptide repeats (8 copies)
C6P53_RS19980	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C6P53_RS19995	COG3237	CsbD-like
C6P53_RS20000	COG0735	belongs to the Fur family
C6P53_RS20020	COG0604	alcohol dehydrogenase
C6P53_RS20045	COG3700	Belongs to the class B bacterial acid phosphatase family
C6P53_RS20050	COG0432	Pfam Uncharacterised protein family UPF0047
C6P53_RS20060	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C6P53_RS20065	COG0629	single-stranded DNA binding
C6P53_RS20080	COG4943	cyclic-guanylate-specific phosphodiesterase activity
C6P53_RS20085	COG2207	Transcriptional regulator
C6P53_RS20090	COG0789	Transcriptional regulator
C6P53_RS20110	COG2252	PERMEase
C6P53_RS20120	COG1357	PFAM Pentapeptide repeats (8 copies)
C6P53_RS20130	COG3162	membrane
C6P53_RS20135	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C6P53_RS20150	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
C6P53_RS20155	COG0437	4 iron, 4 sulfur cluster binding
C6P53_RS20160	COG3301	Polysulphide reductase, NrfD
C6P53_RS20170	COG3088	subunit of a heme lyase
C6P53_RS20175	COG4235	cytochrome complex assembly
C6P53_RS20185	COG1301	dicarboxylic acid transport
C6P53_RS20205	COG1289	transmembrane transporter activity
C6P53_RS20220	COG2015	COG2015, Alkyl sulfatase and related hydrolases
C6P53_RS20225	COG0698	ribose 5-phosphate isomerase
C6P53_RS20235	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C6P53_RS20240	COG0456	acetyltransferase
C6P53_RS20245	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
C6P53_RS20255	COG4778	phosphonate C-P lyase system protein PhnL
C6P53_RS20260	COG4107	phosphonate C-P lyase system protein PhnK
C6P53_RS20265	COG3627	carbon phosphorus lyase activity
C6P53_RS20270	COG3626	phosphonate metabolism
C6P53_RS20275	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
C6P53_RS20280	COG3624	Phosphonate C-P lyase system protein PhnG
C6P53_RS20285	COG2188	Transcriptional regulator
C6P53_RS20290	COG3639	organic phosphonate transmembrane transporter activity
C6P53_RS20295	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
C6P53_RS20305	COG2764	glyoxalase bleomycin resistance protein dioxygenase
C6P53_RS20320	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C6P53_RS20335	COG0477	Major facilitator Superfamily
C6P53_RS20345	COG0642	Histidine kinase
C6P53_RS20350	COG0745	RESPONSE REGULATOR receiver
C6P53_RS20360	COG0531	amino acid
C6P53_RS20365	COG2207	Transcriptional regulator
C6P53_RS20370	COG1982	Orn Lys Arg decarboxylase major
C6P53_RS20375	COG2169	Transcriptional regulator
C6P53_RS20390	COG2211	Major facilitator Superfamily
C6P53_RS20395	COG3647	Membrane
C6P53_RS20400	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C6P53_RS20400	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C6P53_RS20415	COG4565	transcriptional regulatory protein
C6P53_RS20420	COG3290	protein histidine kinase activity
C6P53_RS20425	COG3592	Divergent 4Fe-4S mono-cluster
C6P53_RS20430	COG2388	GCN5-related N-acetyl-transferase
C6P53_RS20450	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C6P53_RS20455	COG3104	oligopeptide transport
C6P53_RS20460	COG1982	Orn Lys Arg decarboxylase major
C6P53_RS20470	COG3710	Transcriptional regulator
C6P53_RS20510	COG0305	Participates in initiation and elongation during chromosome replication
C6P53_RS20565	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C6P53_RS20770	COG2994	toxin metabolic process
C6P53_RS20775	COG2831	hemolysin activation secretion protein
C6P53_RS20875	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
C6P53_RS20880	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
C6P53_RS21035	COG2841	Protein conserved in bacteria
C6P53_RS21040	COG2823	Periplasmic or secreted lipoprotein
C6P53_RS21065	COG0210	DNA helicase
C6P53_RS21100	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C6P53_RS21105	COG1027	Aspartate ammonia-lyase
C6P53_RS21110	COG3030	protein affecting phage T7 exclusion by the F plasmid
C6P53_RS21140	COG3547	Transposase (IS116 IS110 IS902 family)
C6P53_RS21145	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C6P53_RS21160	COG1263	PTS System
C6P53_RS21160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6P53_RS21165	COG0366	Alpha amylase catalytic
C6P53_RS21170	COG1328	CTP reductase activity
C6P53_RS21175	COG0602	queuosine metabolic process
C6P53_RS21185	COG3077	Addiction module antitoxin, RelB DinJ family
C6P53_RS21195	COG3783	Cytochrome b(562)
C6P53_RS21225	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6P53_RS21230	COG1129	ABC transporter
C6P53_RS21240	COG1879	ABC-type sugar transport system periplasmic component
C6P53_RS21245	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
C6P53_RS21250	COG4974	Belongs to the 'phage' integrase family
C6P53_RS21350	COG4695	Portal protein
C6P53_RS21450	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6P53_RS21450	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6P53_RS21455	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C6P53_RS21490	COG2105	PFAM AIG2 family protein
C6P53_RS21495	COG2911	Protein conserved in bacteria
C6P53_RS21525	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
C6P53_RS21535	COG0737	Belongs to the 5'-nucleotidase family
C6P53_RS21540	COG1733	regulation of RNA biosynthetic process
C6P53_RS21545	COG0702	epimerase
C6P53_RS21550	COG0697	spore germination
C6P53_RS21560	COG1113	amino acid transport
C6P53_RS21575	COG3061	Opacity-associated protein A
C6P53_RS21585	COG0675	Transposase, IS605 OrfB family
C6P53_RS21610	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C6P53_RS21630	COG3477	response to acidic pH
C6P53_RS21660	COG3037	sugar-specific permease SgaT UlaA
C6P53_RS21675	COG1073	alpha beta
C6P53_RS21680	COG3650	response to hydrogen peroxide
C6P53_RS21695	COG1960	acyl-CoA dehydrogenase activity
C6P53_RS21700	COG0754	glutathionylspermidine amidase activity
C6P53_RS21705	COG5463	Belongs to the UPF0441 family
C6P53_RS21710	COG3766	membrane
C6P53_RS21720	COG1842	Phage shock protein A
C6P53_RS21725	COG3789	protein conserved in bacteria
C6P53_RS21735	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C6P53_RS21740	COG0557	exoribonuclease II activity
C6P53_RS21755	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
C6P53_RS21760	COG0330	HflC and HflK could
C6P53_RS21765	COG0330	HflC and HflK could
C6P53_RS21770	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C6P53_RS21790	COG0860	N-Acetylmuramoyl-L-alanine amidase
C6P53_RS21795	COG0802	atpase or kinase
C6P53_RS21800	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C6P53_RS21800	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C6P53_RS21865	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C6P53_RS21880	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C6P53_RS21890	COG2076	Multidrug Resistance protein
C6P53_RS21895	COG5510	response to toxic substance
C6P53_RS21900	COG5510	response to toxic substance
C6P53_RS21910	COG1509	lysine 2,3-aminomutase activity
C6P53_RS21930	COG0251	oxidation-reduction process
C6P53_RS21955	COG0251	oxidation-reduction process
C6P53_RS21960	COG1028	Short-chain dehydrogenase reductase Sdr
C6P53_RS21965	COG1309	transcriptional regulator
C6P53_RS21985	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
C6P53_RS21990	COG0456	acetyltransferase
C6P53_RS22000	COG0525	valine-tRNA ligase activity
C6P53_RS22005	COG2927	DNA polymerase III (CHI subunit)
C6P53_RS22015	COG0795	lipopolysaccharide-transporting ATPase activity
C6P53_RS22020	COG0795	lipopolysaccharide-transporting ATPase activity
C6P53_RS22025	COG0433	COG0433 Predicted ATPase
C6P53_RS22030	COG1609	Transcriptional regulator
C6P53_RS22035	COG2610	gluconate transmembrane transporter activity
C6P53_RS22040	COG1028	Short-chain dehydrogenase reductase Sdr
C6P53_RS22050	COG3265	gluconokinase activity
C6P53_RS22065	COG0582	viral genome integration into host DNA
C6P53_RS22090	COG4133	protoheme IX ABC transporter activity
C6P53_RS22120	COG2085	NADP oxidoreductase coenzyme F420-dependent
C6P53_RS22125	COG1120	ATPase activity
C6P53_RS22130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6P53_RS22135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6P53_RS22140	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
C6P53_RS22145	COG4772	TonB-dependent receptor
C6P53_RS22150	COG3712	iron ion homeostasis
C6P53_RS22155	COG1595	DNA-templated transcription, initiation
C6P53_RS22175	COG4372	Transposase
C6P53_RS22180	COG3436	PFAM IS66 Orf2 family protein
C6P53_RS22265	COG2020	methyltransferase activity
C6P53_RS22295	COG2003	Belongs to the UPF0758 family
C6P53_RS22375	COG0582	viral genome integration into host DNA
C6P53_RS22395	COG3539	Fimbrial protein
C6P53_RS22400	COG3121	Chaperone
C6P53_RS22405	COG3188	usher protein
C6P53_RS22410	COG3539	Fimbrial protein
C6P53_RS22415	COG3539	Fimbrial protein
C6P53_RS22420	COG3539	Fimbrial protein
C6P53_RS22425	COG2610	gluconate transmembrane transporter activity
C6P53_RS22450	COG2186	Transcriptional regulator
C6P53_RS22470	COG0583	DNA-binding transcription factor activity
C6P53_RS22480	COG0700	Nucleoside recognition
C6P53_RS22485	COG3366	ferrous iron transmembrane transporter activity
C6P53_RS22500	COG0477	Major facilitator Superfamily
C6P53_RS22515	COG1924	4 iron, 4 sulfur cluster binding
C6P53_RS22520	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
C6P53_RS22525	COG2733	membrane
C6P53_RS22530	COG2814	Major facilitator Superfamily
C6P53_RS22550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C6P53_RS22555	COG5457	Domain of unknown function (DUF1127)
C6P53_RS22565	COG0523	cobalamin synthesis protein
C6P53_RS22585	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C6P53_RS22590	COG2368	4-hydroxyphenylacetate
C6P53_RS22610	COG3971	2-oxopent-4-enoate hydratase activity
C6P53_RS22625	COG1012	belongs to the aldehyde dehydrogenase family
C6P53_RS22635	COG1846	Transcriptional regulator
C6P53_RS22640	COG0840	transmembrane signaling receptor activity
C6P53_RS22650	COG1802	Transcriptional regulator
C6P53_RS22655	COG1063	alcohol dehydrogenase
C6P53_RS22670	COG1484	DNA-dependent DNA replication
C6P53_RS22685	COG2966	Psort location CytoplasmicMembrane, score
C6P53_RS22690	COG2197	response regulator
C6P53_RS22700	COG4114	ferric iron reductase
C6P53_RS22730	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
C6P53_RS22735	COG0456	acetyltransferase
C6P53_RS22740	COG1011	Hydrolase
C6P53_RS22760	COG4667	esterase of the alpha-beta hydrolase superfamily
C6P53_RS22765	COG0084	hydrolase, TatD family'
C6P53_RS22775	COG1328	CTP reductase activity
C6P53_RS22810	COG3726	membrane protein affecting hemolysin expression
C6P53_RS22815	COG0560	Phosphoserine phosphatase
C6P53_RS22820	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C6P53_RS22825	COG3172	ATPase kinase involved in NAD metabolism
C6P53_RS22825	COG1056	cytidyltransferase-related domain
C6P53_RS22830	COG0488	(ABC) transporter
C6P53_RS22840	COG0741	lytic transglycosylase activity
C6P53_RS22870	COG2207	Transcriptional regulator
C6P53_RS22870	COG3708	Transcriptional regulator
C6P53_RS22875	COG3045	CreA protein
C6P53_RS22880	COG0745	RESPONSE REGULATOR receiver
C6P53_RS22885	COG2205	protein histidine kinase activity
C6P53_RS22890	COG4452	Inner membrane protein CreD
C6P53_RS22895	COG0745	RESPONSE REGULATOR receiver
C6P53_RS22905	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
C6P53_RS22915	COG0460	homoserine dehydrogenase
C6P53_RS22915	COG0527	aspartate kinase activity
C6P53_RS22925	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C6P53_RS22940	COG3547	Transposase (IS116 IS110 IS902 family)
C6P53_RS22950	COG1115	amino acid carrier protein
C6P53_RS22960	COG0521	Mo-molybdopterin cofactor biosynthetic process
C6P53_RS22970	COG4735	regulation of single-species biofilm formation
C6P53_RS22975	COG4735	regulation of single-species biofilm formation
C6P53_RS23005	COG0583	DNA-binding transcription factor activity
C6P53_RS23040	COG0196	riboflavin kinase activity
C6P53_RS23055	COG1047	Peptidyl-prolyl cis-trans
C6P53_RS23080	COG0505	Belongs to the CarA family
C6P53_RS23140	COG0644	oxidoreductase
C6P53_RS23145	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C6P53_RS23150	COG2271	Major facilitator Superfamily
C6P53_RS23215	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
C6P53_RS23220	COG0564	pseudouridine synthase activity
C6P53_RS23235	COG0235	Class ii aldolase
C6P53_RS23255	COG4977	sequence-specific DNA binding
C6P53_RS23260	COG0586	Pfam SNARE associated Golgi protein
C6P53_RS23270	COG1178	ABC-type Fe3 transport system permease component
C6P53_RS23290	COG2814	Major facilitator Superfamily
C6P53_RS23320	COG0583	DNA-binding transcription factor activity
C6P53_RS23325	COG0583	DNA-binding transcription factor activity
C6P53_RS23335	COG0440	acetolactate synthase activity
C6P53_RS23345	COG1609	Transcriptional regulator
C6P53_RS23370	COG3116	cell division
C6P53_RS23380	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C6P53_RS23415	COG1181	Belongs to the D-alanine--D-alanine ligase family
C6P53_RS23420	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C6P53_RS23425	COG0849	cell division
C6P53_RS23450	COG0494	nUDIX hydrolase
C6P53_RS23465	COG0237	dephospho-CoA kinase activity
C6P53_RS23480	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C6P53_RS23485	COG4969	Belongs to the N-Me-Phe pilin family
C6P53_RS23495	COG0157	Belongs to the NadC ModD family
C6P53_RS23505	COG3725	Membrane protein required for beta-lactamase induction
C6P53_RS23510	COG1113	amino acid transport
C6P53_RS23515	COG2186	Transcriptional regulator
C6P53_RS23530	COG0508	dehydrogenase complex catalyzes the overall conversion of
C6P53_RS23535	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C6P53_RS23540	COG3064	Membrane
C6P53_RS23550	COG1049	propionate catabolic process, 2-methylcitrate cycle
C6P53_RS23580	COG4993	Dehydrogenase
C6P53_RS23585	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
C6P53_RS23590	COG0288	reversible hydration of carbon dioxide
C6P53_RS23595	COG1131	(ABC) transporter
C6P53_RS23600	COG0842	Transport permease protein
C6P53_RS23605	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6P53_RS23630	COG5464	transposase or invertase
C6P53_RS23645	COG3539	Fimbrial protein
C6P53_RS23650	COG3539	Fimbrial protein
C6P53_RS23655	COG3539	Fimbrial protein
C6P53_RS23660	COG3539	Fimbrial protein
C6P53_RS23670	COG3121	Chaperone
C6P53_RS23675	COG3539	Fimbrial protein
C6P53_RS23680	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C6P53_RS23685	COG0617	tRNA 3'-terminal CCA addition
C6P53_RS23695	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C6P53_RS23705	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C6P53_RS23720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C6P53_RS23730	COG1120	ATPase activity
C6P53_RS23735	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C6P53_RS23740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6P53_RS23760	COG2860	membrane
C6P53_RS23765	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C6P53_RS23810	COG0024	Methionine aminopeptidase
C6P53_RS23850	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C6P53_RS23855	COG0575	Belongs to the CDS family
C6P53_RS23870	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
C6P53_RS23875	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C6P53_RS23915	COG0346	lactoylglutathione lyase activity
C6P53_RS23920	COG0037	tRNA processing
C6P53_RS23925	COG4568	rho-dependent transcription termination
C6P53_RS23935	COG4681	YaeQ
C6P53_RS23940	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
C6P53_RS23945	COG3015	lipoprotein NlpE involved in copper resistance
C6P53_RS23950	COG0791	NLP P60 protein
C6P53_RS23960	COG1720	tRNA m6t6A37 methyltransferase activity
C6P53_RS23970	COG1464	Belongs to the NlpA lipoprotein family
C6P53_RS23975	COG2011	ABC-type metal ion transport system permease component
C6P53_RS23985	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C6P53_RS24020	COG0656	L-ascorbic acid biosynthetic process
C6P53_RS24035	COG2226	methyltransferase
C6P53_RS24040	COG0741	lytic transglycosylase activity
C6P53_RS24040	COG1388	LysM domain
C6P53_RS24045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C6P53_RS24050	COG2226	methyltransferase
C6P53_RS24060	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6P53_RS24100	COG3436	PFAM IS66 Orf2 family protein
C6P53_RS24140	COG2003	Belongs to the UPF0758 family
C6P53_RS24245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6P53_RS24250	COG1120	ATPase activity
C6P53_RS24365	COG0823	Involved in the tonB-independent uptake of proteins
C6P53_RS24370	COG1028	Short-chain dehydrogenase reductase Sdr
C6P53_RS24375	COG1917	Cupin 2, conserved barrel domain protein
C6P53_RS24380	COG2211	Major facilitator Superfamily
C6P53_RS24415	COG0440	acetolactate synthase activity
C6P53_RS24420	COG1349	DNA-binding transcription factor activity
C6P53_RS24430	COG0738	Major facilitator superfamily
C6P53_RS24450	COG3037	sugar-specific permease SgaT UlaA
C6P53_RS24460	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6P53_RS24500	COG3210	domain, Protein
C6P53_RS24600	COG2197	response regulator
C6P53_RS24645	COG0121	glutamine amidotransferase
C6P53_RS24650	COG3034	peptidoglycan biosynthetic process
C6P53_RS24655	COG0791	NLP P60 protein
C6P53_RS24670	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C6P53_RS24675	COG0454	-acetyltransferase
C6P53_RS24685	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
C6P53_RS24710	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C6P53_RS24735	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C6P53_RS24745	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C6P53_RS24750	COG2080	2 iron, 2 sulfur cluster binding
C6P53_RS24760	COG3477	response to acidic pH
C6P53_RS24770	COG0727	PFAM Uncharacterised protein family (UPF0153)
C6P53_RS24850	COG3708	Transcriptional regulator
C6P53_RS24850	COG2207	Transcriptional regulator
C6P53_RS24860	COG3059	membrane
C6P53_RS24870	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C6P53_RS24880	COG0247	lactate metabolic process
C6P53_RS24940	COG2200	EAL domain
C6P53_RS24940	COG2771	luxR family
C6P53_RS24945	COG0583	DNA-binding transcription factor activity
C6P53_RS24975	COG1304	FMN binding
C6P53_RS24980	COG0549	Belongs to the carbamate kinase family
C6P53_RS24985	COG0402	S-adenosylhomocysteine deaminase activity
C6P53_RS24995	COG1879	ABC-type sugar transport system periplasmic component
C6P53_RS25000	COG1129	ABC transporter
C6P53_RS25005	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6P53_RS25015	COG1064	alcohol dehydrogenase
C6P53_RS25030	COG1280	lysine exporter protein (LysE YggA)
C6P53_RS25040	COG3829	transcription factor binding
C6P53_RS25045	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C6P53_RS25050	COG0372	Belongs to the citrate synthase family
C6P53_RS25060	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C6P53_RS25065	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C6P53_RS25070	COG0402	S-adenosylhomocysteine deaminase activity
C6P53_RS25075	COG0583	DNA-binding transcription factor activity
C6P53_RS25080	COG0288	reversible hydration of carbon dioxide
C6P53_RS25090	COG2807	transmembrane transport
C6P53_RS25095	COG2223	nitrite transmembrane transporter activity
C6P53_RS25110	COG1609	Transcriptional regulator
C6P53_RS25150	COG2814	Major facilitator Superfamily
C6P53_RS25185	COG1215	transferase activity, transferring glycosyl groups
C6P53_RS25190	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C6P53_RS25205	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
C6P53_RS25210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C6P53_RS25220	COG0113	porphobilinogen synthase activity
C6P53_RS25235	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C6P53_RS25240	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C6P53_RS25250	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
C6P53_RS25275	COG1181	Belongs to the D-alanine--D-alanine ligase family
C6P53_RS25290	COG1785	Belongs to the alkaline phosphatase family
C6P53_RS25305	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C6P53_RS25330	COG4126	flavin adenine dinucleotide binding
C6P53_RS25355	COG1940	carbohydrate kinase activity
C6P53_RS25365	COG0419	ATPase involved in DNA repair
C6P53_RS25375	COG0745	RESPONSE REGULATOR receiver
C6P53_RS25390	COG1113	amino acid transport
C6P53_RS25395	COG0366	Alpha amylase catalytic
C6P53_RS25415	COG1862	Preprotein translocase
C6P53_RS25420	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C6P53_RS25430	COG1403	HNH endonuclease
C6P53_RS25435	COG3248	Nucleoside-binding outer membrane protein
C6P53_RS25440	COG4238	major outer membrane lipoprotein
C6P53_RS25450	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C6P53_RS25450	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C6P53_RS25470	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C6P53_RS25475	COG0667	Aldo Keto reductase
C6P53_RS25485	COG0142	geranyltranstransferase activity
C6P53_RS25500	COG0693	protein deglycase activity
C6P53_RS25505	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C6P53_RS25540	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C6P53_RS25550	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C6P53_RS25555	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C6P53_RS25560	COG2223	nitrite transmembrane transporter activity
C6P53_RS25570	COG0271	Belongs to the BolA IbaG family
C6P53_RS25595	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C6P53_RS25600	COG0776	regulation of translation
C6P53_RS25605	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C6P53_RS25610	COG1555	photosystem II stabilization
C6P53_RS25615	COG0824	Thioesterase
C6P53_RS25635	COG1522	sequence-specific DNA binding
C6P53_RS25640	COG1132	(ABC) transporter
C6P53_RS25650	COG0347	Belongs to the P(II) protein family
C6P53_RS25660	COG1946	Acyl-CoA thioesterase
C6P53_RS25665	COG3126	Type III secretion system lipoprotein chaperone (YscW)
C6P53_RS25670	COG3695	enzyme binding
C6P53_RS25680	COG5507	3-demethylubiquinone-9 3-methyltransferase
C6P53_RS25685	COG4943	cyclic-guanylate-specific phosphodiesterase activity
C6P53_RS25695	COG0110	maltose O-acetyltransferase activity
C6P53_RS25710	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C6P53_RS25715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6P53_RS25720	COG1309	transcriptional regulator
C6P53_RS25740	COG3923	Primosomal replication protein n
C6P53_RS25745	COG2832	Protein of unknown function (DUF454)
C6P53_RS25760	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C6P53_RS25800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6P53_RS25825	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C6P53_RS25835	COG3735	TraB family
C6P53_RS25845	COG3093	addiction module antidote protein HigA
C6P53_RS25850	COG2217	Heavy metal translocating P-type atpase
C6P53_RS25855	COG2066	Belongs to the glutaminase family
C6P53_RS25865	COG0789	Transcriptional regulator
C6P53_RS25870	COG1585	Membrane protein implicated in regulation of membrane protease activity
C6P53_RS25875	COG0330	HflC and HflK could
C6P53_RS25880	COG4619	ABC transporter
C6P53_RS25885	COG0390	transport system, permease component
C6P53_RS25890	COG3118	belongs to the thioredoxin family
C6P53_RS25895	COG0300	oxidoreductase activity
C6P53_RS25900	COG2755	lipolytic protein G-D-S-L family
C6P53_RS25905	COG4181	ATPase activity
C6P53_RS25915	COG3209	COG3209 Rhs family protein
C6P53_RS25945	COG0583	DNA-binding transcription factor activity
C6P53_RS25955	COG1414	Transcriptional regulator
C6P53_RS25960	COG3960	tartronate-semialdehyde synthase activity
C6P53_RS25965	COG3622	Belongs to the hyi family
C6P53_RS25970	COG2084	Dehydrogenase
C6P53_RS25975	COG1953	Uracil, thiamine, allantoin
C6P53_RS25985	COG2233	PERMEase
C6P53_RS25990	COG1929	Belongs to the glycerate kinase type-1 family
C6P53_RS25995	COG3257	ureidoglycine aminohydrolase activity
C6P53_RS26000	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C6P53_RS26010	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C6P53_RS26015	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C6P53_RS26030	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C6P53_RS26035	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C6P53_RS26050	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C6P53_RS26065	COG2501	S4 domain
C6P53_RS26080	COG3121	Chaperone
C6P53_RS26095	COG3539	Fimbrial protein
C6P53_RS26100	COG3539	Fimbrial protein
C6P53_RS26105	COG2197	response regulator
C6P53_RS26120	COG2207	Transcriptional regulator
C6P53_RS26135	COG4783	chaperone-mediated protein folding
C6P53_RS26145	COG5433	transposase activity
C6P53_RS26190	COG5002	protein histidine kinase activity
C6P53_RS26195	COG0745	RESPONSE REGULATOR receiver
C6P53_RS26210	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6P53_RS26215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6P53_RS26230	COG0668	transmembrane transport
C6P53_RS26240	COG2315	Protein conserved in bacteria
C6P53_RS26275	COG2977	Belongs to the P-Pant transferase superfamily
C6P53_RS26295	COG3251	PFAM MbtH domain protein
C6P53_RS26300	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
C6P53_RS26300	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C6P53_RS26305	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
C6P53_RS26310	COG1120	ATPase activity
C6P53_RS26315	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6P53_RS26320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6P53_RS26335	COG1169	isochorismate synthase
C6P53_RS26345	COG1535	isochorismatase
C6P53_RS26345	COG3433	isochorismatase activity
C6P53_RS26350	COG1028	Short-chain dehydrogenase reductase Sdr
C6P53_RS26355	COG2050	protein possibly involved in aromatic compounds catabolism
C6P53_RS26365	COG2879	small protein
C6P53_RS26375	COG0436	Aminotransferase
C6P53_RS26380	COG1475	DNA binding
C6P53_RS26395	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C6P53_RS26400	COG0450	alkyl hydroperoxide reductase
C6P53_RS26405	COG3634	alkyl hydroperoxide reductase activity
C6P53_RS26410	COG0589	response to stress
C6P53_RS26415	COG1063	alcohol dehydrogenase
C6P53_RS26425	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C6P53_RS26435	COG3719	Belongs to the RNase T2 family
C6P53_RS26440	COG0471	metal ion transport
C6P53_RS26460	COG2301	Belongs to the HpcH HpaI aldolase family
C6P53_RS26470	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
C6P53_RS26475	COG3290	protein histidine kinase activity
C6P53_RS26480	COG4565	transcriptional regulatory protein
C6P53_RS26485	COG3069	C4-dicarboxylate transmembrane transporter activity
C6P53_RS26510	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C6P53_RS26515	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C6P53_RS26530	COG0583	DNA-binding transcription factor activity
C6P53_RS26550	COG1686	Belongs to the peptidase S11 family
C6P53_RS26555	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C6P53_RS26560	COG0772	Belongs to the SEDS family
C6P53_RS26565	COG0768	penicillin binding
C6P53_RS26575	COG0799	negative regulation of ribosome biogenesis
C6P53_RS26580	COG0406	alpha-ribazole phosphatase activity
C6P53_RS26605	COG2888	peptidyl-tyrosine sulfation
C6P53_RS26610	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C6P53_RS26620	COG2214	Heat shock protein DnaJ domain protein
C6P53_RS26625	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C6P53_RS26635	COG2214	Heat shock protein DnaJ domain protein
C6P53_RS26640	COG0443	Heat shock 70 kDa protein
C6P53_RS26650	COG1126	abc transporter atp-binding protein
C6P53_RS26655	COG0765	amino acid transport
C6P53_RS26660	COG0765	amino acid transport
C6P53_RS26665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6P53_RS26680	COG0815	Transfers the fatty acyl group on membrane lipoproteins
C6P53_RS26685	COG4535	Mg2 and Co2 transporter CorC
C6P53_RS26695	COG1702	phosphate starvation-inducible protein PhoH
C6P53_RS26705	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C6P53_RS26750	COG0367	asparagine synthase
C6P53_RS26760	COG0647	UMP catabolic process
C6P53_RS26805	COG0735	belongs to the Fur family
C6P53_RS26825	COG0596	Alpha beta hydrolase
C6P53_RS26830	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
C6P53_RS26835	COG0033	Phosphoglucomutase
C6P53_RS26840	COG0531	amino acid
C6P53_RS26845	COG1982	Orn Lys Arg decarboxylase major
C6P53_RS26860	COG0745	RESPONSE REGULATOR receiver
C6P53_RS26865	COG2205	protein histidine kinase activity
C6P53_RS26895	COG3209	COG3209 Rhs family protein
C6P53_RS26915	COG3272	Protein of unknown function (DUF1722)
C6P53_RS26920	COG0415	Belongs to the DNA photolyase family
C6P53_RS26930	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C6P53_RS26935	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C6P53_RS26940	COG1984	allophanate hydrolase subunit 2
C6P53_RS26955	COG3180	Ammonia monooxygenase
C6P53_RS26960	COG3539	Fimbrial protein
C6P53_RS26965	COG3121	Chaperone
C6P53_RS26975	COG3539	Fimbrial protein
C6P53_RS26980	COG0372	Belongs to the citrate synthase family
C6P53_RS26995	COG2009	succinate dehydrogenase
C6P53_RS27000	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
C6P53_RS27005	COG1053	succinate dehydrogenase
C6P53_RS27010	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C6P53_RS27015	COG0567	Dehydrogenase, E1 component
C6P53_RS27020	COG0508	dehydrogenase complex catalyzes the overall conversion of
C6P53_RS27030	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C6P53_RS27035	COG2188	Transcriptional regulator
C6P53_RS27045	COG0383	alpha-mannosidase activity
C6P53_RS27065	COG4890	Cyd operon protein YbgT
C6P53_RS27070	COG3790	cyd operon protein YbgE
C6P53_RS27075	COG0824	Thioesterase
C6P53_RS27080	COG0811	peptide transport
C6P53_RS27085	COG0848	biopolymer transport protein
C6P53_RS27100	COG2885	chlorophyll binding
C6P53_RS27105	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
C6P53_RS27150	COG3201	nicotinamide mononucleotide transporter
C6P53_RS27155	COG1230	cation diffusion facilitator family transporter
C6P53_RS27170	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C6P53_RS27190	COG1085	galactose-1-phosphate uridylyltransferase
C6P53_RS27195	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C6P53_RS27200	COG1119	ATPase activity
C6P53_RS27220	COG0725	ABC transporter, periplasmic molybdate-binding protein
C6P53_RS27225	COG4149	molybdate abc transporter
C6P53_RS27235	COG0561	phosphatase activity
C6P53_RS27245	COG0583	DNA-binding transcription factor activity
C6P53_RS27255	COG0471	metal ion transport
C6P53_RS27260	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C6P53_RS27265	COG4677	pectinesterase activity
C6P53_RS27275	COG1881	PFAM PEBP family protein
C6P53_RS27280	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C6P53_RS27295	COG2226	methyltransferase
C6P53_RS27300	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C6P53_RS27310	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C6P53_RS27320	COG0521	Mo-molybdopterin cofactor biosynthetic process
C6P53_RS27330	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C6P53_RS27335	COG0314	molybdopterin synthase activity
C6P53_RS27340	COG0670	Belongs to the BI1 family
C6P53_RS27350	COG0670	Belongs to the BI1 family
C6P53_RS27355	COG0392	lysyltransferase activity
C6P53_RS27360	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C6P53_RS27365	COG3568	Endonuclease Exonuclease Phosphatase
C6P53_RS27375	COG0842	Transport permease protein
C6P53_RS27380	COG0842	Transport permease protein
C6P53_RS27395	COG1309	transcriptional regulator
C6P53_RS27415	COG1199	ATP-dependent helicase activity
C6P53_RS27420	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C6P53_RS27425	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
C6P53_RS27435	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C6P53_RS27445	COG4774	siderophore transport
C6P53_RS27460	COG0668	transmembrane transport
C6P53_RS27470	COG0765	amino acid transport
C6P53_RS27475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6P53_RS27510	COG2194	sulfuric ester hydrolase activity
C6P53_RS27520	COG1321	iron dependent repressor
C6P53_RS27525	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C6P53_RS27530	COG1376	ErfK ybiS ycfS ynhG family protein
C6P53_RS27535	COG0488	(ABC) transporter
C6P53_RS27570	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C6P53_RS27575	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C6P53_RS27580	COG0303	'Molybdopterin
C6P53_RS27585	COG1446	asparaginase
C6P53_RS27610	COG2200	EAL domain
C6P53_RS27615	COG2199	diguanylate cyclase activity
C6P53_RS27635	COG0625	glutathione transferase activity
C6P53_RS27640	COG1686	Belongs to the peptidase S11 family
C6P53_RS27645	COG1349	DNA-binding transcription factor activity
C6P53_RS27650	COG0671	phosphoesterase, PA-phosphatase related
C6P53_RS27655	COG2814	Major facilitator Superfamily
C6P53_RS27665	COG0561	phosphatase activity
C6P53_RS27670	COG0738	Major facilitator superfamily
C6P53_RS27675	COG3226	Transcriptional regulator
C6P53_RS27680	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
C6P53_RS27720	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C6P53_RS27760	COG4695	Portal protein
C6P53_RS27870	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C6P53_RS27925	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C6P53_RS27935	COG0778	Nitroreductase
C6P53_RS27955	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C6P53_RS27965	COG1176	ABC-type spermidine putrescine transport system, permease component I
C6P53_RS27990	COG4160	amino acid transport
C6P53_RS27995	COG4215	(ABC) transporter
C6P53_RS28000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6P53_RS28005	COG1126	abc transporter atp-binding protein
C6P53_RS28020	COG3023	N-Acetylmuramoyl-L-alanine amidase
C6P53_RS28025	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C6P53_RS28030	COG0702	epimerase
C6P53_RS28035	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
C6P53_RS28040	COG0028	Belongs to the TPP enzyme family
C6P53_RS28045	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C6P53_RS28055	COG2431	L-lysine efflux transmembrane transporter activity
C6P53_RS28065	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C6P53_RS28090	COG1121	(ABC) transporter
C6P53_RS28095	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C6P53_RS28100	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C6P53_RS28550	COG5001	Diguanylate cyclase
C6P53_RS28550	COG3300	MHYT domain
C6P53_RS28675	COG0697	spore germination
C6P53_RS28705	COG0697	spore germination
C6P53_RS28780	COG0446	pyridine nucleotide-disulphide oxidoreductase
C6P53_RS28780	COG1902	pentaerythritol trinitrate reductase activity
C6P53_RS28835	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C6P53_RS28860	COG2819	hydrolase of the alpha beta superfamily
C6P53_RS28865	COG2382	esterase
C6P53_RS28955	COG1538	Outer membrane efflux protein
C6P53_RS28965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6P53_RS28995	COG4571	Outer membrane protease