locus-tag	class	description
A5955_RS00065	COG4220	transposase activity
A5955_RS00115	COG3772	lysozyme
A5955_RS00160	COG2207	Transcriptional regulator
A5955_RS00180	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
A5955_RS00185	COG1403	HNH endonuclease
A5955_RS00225	COG1846	Transcriptional regulator
A5955_RS00240	COG1396	sequence-specific DNA binding
A5955_RS00265	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A5955_RS00305	COG0477	Major facilitator Superfamily
A5955_RS00310	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A5955_RS00315	COG0217	transcriptional regulatory protein
A5955_RS00335	COG0583	DNA-binding transcription factor activity
A5955_RS00340	COG0583	DNA-binding transcription factor activity
A5955_RS00350	COG1376	ErfK ybiS ycfS ynhG family protein
A5955_RS00365	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
A5955_RS00375	COG4771	TonB-dependent receptor
A5955_RS00380	COG1475	DNA binding
A5955_RS00385	COG3969	phosphoadenosine phosphosulfate
A5955_RS00460	COG2003	Belongs to the UPF0758 family
A5955_RS00490	COG4917	ethanolamine utilization protein
A5955_RS00500	COG1289	transmembrane transporter activity
A5955_RS00510	COG1686	Belongs to the peptidase S11 family
A5955_RS00515	COG2925	Exonuclease
A5955_RS00520	COG0425	Belongs to the sulfur carrier protein TusA family
A5955_RS00525	COG2391	methyltransferase activity
A5955_RS00530	COG0531	amino acid
A5955_RS00535	COG0583	DNA-binding transcription factor activity
A5955_RS00540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A5955_RS00545	COG4115	mRNA cleavage
A5955_RS00550	COG2161	toxin-antitoxin pair type II binding
A5955_RS00570	COG0131	Imidazoleglycerol-phosphate dehydratase
A5955_RS00570	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
A5955_RS00575	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
A5955_RS00590	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
A5955_RS00590	COG0140	phosphoribosyl-ATP diphosphatase activity
A5955_RS00595	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
A5955_RS00600	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
A5955_RS00605	COG5433	transposase activity
A5955_RS00610	COG5433	transposase activity
A5955_RS00625	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
A5955_RS00630	COG1216	Glycosyl transferase, family 2
A5955_RS00655	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A5955_RS00660	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
A5955_RS00660	COG0662	Cupin 2, conserved barrel domain protein
A5955_RS00665	COG1051	belongs to the nudix hydrolase family
A5955_RS00670	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
A5955_RS00680	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A5955_RS00685	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A5955_RS00695	COG0438	transferase activity, transferring glycosyl groups
A5955_RS00700	COG2327	Polysaccharide pyruvyl transferase
A5955_RS00705	COG2244	polysaccharide biosynthetic process
A5955_RS00710	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A5955_RS00715	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A5955_RS00720	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
A5955_RS00720	COG0662	Cupin 2, conserved barrel domain protein
A5955_RS00725	COG0297	glycogen (starch) synthase activity
A5955_RS00730	COG1051	belongs to the nudix hydrolase family
A5955_RS00735	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A5955_RS00740	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
A5955_RS00745	COG0110	maltose O-acetyltransferase activity
A5955_RS00750	COG1216	Glycosyl transferase, family 2
A5955_RS00760	COG0438	transferase activity, transferring glycosyl groups
A5955_RS00765	COG1045	serine acetyltransferase
A5955_RS00770	COG0463	Glycosyl transferase, family 2
A5955_RS00775	COG3206	protein involved in exopolysaccharide biosynthesis
A5955_RS00775	COG0489	protein tyrosine kinase activity
A5955_RS00780	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A5955_RS00785	COG1596	polysaccharide export
A5955_RS00790	COG1253	flavin adenine dinucleotide binding
A5955_RS00805	COG2982	Protein involved in outer membrane biogenesis
A5955_RS00815	COG0572	uridine kinase
A5955_RS00820	COG5001	Diguanylate cyclase
A5955_RS00820	COG5002	protein histidine kinase activity
A5955_RS00820	COG3447	MASE1 domain protein
A5955_RS00825	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
A5955_RS00835	COG0443	Heat shock 70 kDa protein
A5955_RS00840	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
A5955_RS00845	COG0631	protein serine/threonine phosphatase activity
A5955_RS00850	COG4245	von Willebrand factor, type A
A5955_RS00875	COG2205	protein histidine kinase activity
A5955_RS00880	COG0745	RESPONSE REGULATOR receiver
A5955_RS00890	COG3609	addiction module antidote protein, CC2985 family
A5955_RS00900	COG0826	peptidase U32
A5955_RS00920	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A5955_RS00930	COG1070	Carbohydrate kinase
A5955_RS00955	COG1069	ribulokinase activity
A5955_RS00965	COG1063	alcohol dehydrogenase
A5955_RS00970	COG3775	system Galactitol-specific IIC component
A5955_RS00975	COG3414	Phosphotransferase system galactitol-specific IIB component
A5955_RS00980	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A5955_RS00995	COG1830	Aldolase
A5955_RS01000	COG2211	Major facilitator Superfamily
A5955_RS01005	COG1397	ADP-ribosylglycohydrolase
A5955_RS01010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A5955_RS01015	COG2188	Transcriptional regulator
A5955_RS01020	COG3757	hydrolase, family 25
A5955_RS01025	COG0351	phosphomethylpyrimidine kinase
A5955_RS01060	COG5455	response to cobalt ion
A5955_RS01065	COG3539	Fimbrial protein
A5955_RS01080	COG3539	Fimbrial protein
A5955_RS01095	COG0489	protein tyrosine kinase activity
A5955_RS01110	COG3831	ATPase activity
A5955_RS01115	COG3831	ATPase activity
A5955_RS01130	COG0714	Associated with various cellular activities
A5955_RS01135	COG2425	protein containing a von Willebrand factor type A (vWA) domain
A5955_RS01140	COG3552	Protein containing von Willebrand factor type A (VWA) domain
A5955_RS01145	COG4715	Zinc finger, swim domain protein
A5955_RS01150	COG4808	Protein conserved in bacteria
A5955_RS01155	COG4807	Protein conserved in bacteria
A5955_RS01160	COG3279	Response regulator of the LytR AlgR family
A5955_RS01165	COG3275	phosphorelay sensor kinase activity
A5955_RS01170	COG0789	Transcriptional regulator
A5955_RS01180	COG1174	glycine betaine transport
A5955_RS01185	COG1125	glycine betaine transport
A5955_RS01190	COG1174	glycine betaine transport
A5955_RS01195	COG1732	Glycine betaine
A5955_RS01200	COG1472	Belongs to the glycosyl hydrolase 3 family
A5955_RS01205	COG0277	FAD linked oxidase domain protein
A5955_RS01210	COG1686	Belongs to the peptidase S11 family
A5955_RS01220	COG0586	Pfam SNARE associated Golgi protein
A5955_RS01225	COG1028	Short-chain dehydrogenase reductase Sdr
A5955_RS01230	COG1538	Outer membrane efflux protein
A5955_RS01240	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A5955_RS01245	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A5955_RS01250	COG0625	glutathione transferase activity
A5955_RS01265	COG2271	Major facilitator Superfamily
A5955_RS01280	COG1346	cytolysis
A5955_RS01290	COG2949	membrane
A5955_RS01300	COG0493	'glutamate synthase
A5955_RS01305	COG0167	dihydroorotate dehydrogenase activity
A5955_RS01305	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
A5955_RS01310	COG4211	Belongs to the binding-protein-dependent transport system permease family
A5955_RS01315	COG1129	ABC transporter
A5955_RS01320	COG1879	ABC-type sugar transport system periplasmic component
A5955_RS01325	COG1609	Transcriptional regulator
A5955_RS01335	COG2311	Membrane
A5955_RS01350	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
A5955_RS01355	COG4771	TonB-dependent receptor
A5955_RS01365	COG0833	amino acid
A5955_RS01370	COG0583	DNA-binding transcription factor activity
A5955_RS01375	COG2855	membrane
A5955_RS01385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A5955_RS01385	COG1522	sequence-specific DNA binding
A5955_RS01390	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A5955_RS01400	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A5955_RS01405	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A5955_RS01410	COG2313	pseudouridylate synthase activity
A5955_RS01415	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A5955_RS01420	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A5955_RS01420	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A5955_RS01420	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
A5955_RS01425	COG1105	Belongs to the carbohydrate kinase PfkB family
A5955_RS01430	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A5955_RS01430	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
A5955_RS01435	COG2814	Major facilitator Superfamily
A5955_RS01450	COG0246	Mannitol dehydrogenase
A5955_RS01455	COG0523	cobalamin synthesis protein
A5955_RS01460	COG0671	phosphoesterase, PA-phosphatase related
A5955_RS01465	COG0791	NLP P60 protein
A5955_RS01470	COG2200	EAL domain
A5955_RS01475	COG4166	transmembrane transport
A5955_RS01480	COG4174	ABC transporter (Permease)
A5955_RS01485	COG4239	(ABC) transporter, permease
A5955_RS01490	COG4172	Belongs to the ABC transporter superfamily
A5955_RS01500	COG2814	Major facilitator Superfamily
A5955_RS01505	COG1187	pseudouridine synthase activity
A5955_RS01510	COG1061	Type III restriction enzyme res subunit
A5955_RS01530	COG3083	sulfuric ester hydrolase activity
A5955_RS01540	COG3468	outer membrane autotransporter barrel domain protein
A5955_RS01550	COG2197	response regulator
A5955_RS01555	COG3088	subunit of a heme lyase
A5955_RS01555	COG4235	cytochrome complex assembly
A5955_RS01560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A5955_RS01565	COG1138	Cytochrome C-type biogenesis protein
A5955_RS01575	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A5955_RS01580	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A5955_RS01585	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A5955_RS01590	COG4133	protoheme IX ABC transporter activity
A5955_RS01595	COG3005	denitrification pathway
A5955_RS01600	COG3043	anaerobic respiration
A5955_RS01605	COG0348	domain, Protein
A5955_RS01610	COG0437	4 iron, 4 sulfur cluster binding
A5955_RS01620	COG3062	negative regulation of establishment of protein localization
A5955_RS01625	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
A5955_RS01625	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
A5955_RS01645	COG4615	Cyclic peptide transporter
A5955_RS01650	COG3145	DNA-N1-methyladenine dioxygenase activity
A5955_RS01655	COG2169	Transcriptional regulator
A5955_RS01655	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A5955_RS01660	COG1477	protein flavinylation
A5955_RS01665	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
A5955_RS01680	COG0642	Histidine kinase
A5955_RS01680	COG2198	Histidine kinase
A5955_RS01685	COG2197	response regulator
A5955_RS01690	COG0784	Response regulator, receiver
A5955_RS01690	COG2205	protein histidine kinase activity
A5955_RS01695	COG4676	Protein conserved in bacteria
A5955_RS01705	COG2373	Large extracellular alpha-helical protein
A5955_RS01710	COG3547	Transposase (IS116 IS110 IS902 family)
A5955_RS01715	COG2373	Large extracellular alpha-helical protein
A5955_RS01720	COG3234	Protein of unknown function (DUF1175)
A5955_RS01725	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
A5955_RS01730	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A5955_RS01740	COG3468	outer membrane autotransporter barrel domain protein
A5955_RS01750	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A5955_RS01755	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A5955_RS01760	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A5955_RS01765	COG3642	lipopolysaccharide core region biosynthetic process
A5955_RS01775	COG0583	DNA-binding transcription factor activity
A5955_RS01785	COG0584	glycerophosphoryl diester phosphodiesterase
A5955_RS01790	COG2271	Major facilitator Superfamily
A5955_RS01795	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
A5955_RS01805	COG0247	lactate metabolic process
A5955_RS01810	COG5464	transposase or invertase
A5955_RS01815	COG3836	Belongs to the HpcH HpaI aldolase family
A5955_RS01820	COG2271	Major facilitator Superfamily
A5955_RS01825	COG4948	Mandelate Racemase Muconate Lactonizing
A5955_RS01830	COG1414	Transcriptional regulator
A5955_RS01850	COG0406	alpha-ribazole phosphatase activity
A5955_RS01895	COG0318	PFAM AMP-dependent synthetase and ligase
A5955_RS01905	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
A5955_RS01920	COG1169	isochorismate synthase
A5955_RS01925	COG4575	ribosome binding
A5955_RS01930	COG2153	protein acetylation
A5955_RS01940	COG5160	protein modification by small protein removal
A5955_RS01945	COG5160	protein modification by small protein removal
A5955_RS01950	COG2234	aminopeptidase activity
A5955_RS01965	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A5955_RS01970	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A5955_RS01980	COG0839	Belongs to the complex I subunit 6 family
A5955_RS01995	COG1034	ATP synthesis coupled electron transport
A5955_RS02000	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
A5955_RS02005	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
A5955_RS02025	COG0583	DNA-binding transcription factor activity
A5955_RS02030	COG0436	Aminotransferase
A5955_RS02040	COG0471	metal ion transport
A5955_RS02040	COG0490	domain, Protein
A5955_RS02045	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A5955_RS02065	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
A5955_RS02070	COG0280	phosphate acetyltransferase
A5955_RS02070	COG0857	belongs to the CobB CobQ family
A5955_RS02075	COG1288	antiporter activity
A5955_RS02080	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
A5955_RS02085	COG0622	Phosphoesterase
A5955_RS02090	COG0625	glutathione transferase activity
A5955_RS02095	COG0625	glutathione transferase activity
A5955_RS02100	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
A5955_RS02105	COG1090	epimerase
A5955_RS02110	COG5464	transposase or invertase
A5955_RS02115	COG4598	ABC transporter
A5955_RS02120	COG4160	amino acid transport
A5955_RS02125	COG4215	(ABC) transporter
A5955_RS02130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A5955_RS02135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A5955_RS02140	COG0163	prenyltransferase activity
A5955_RS02145	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
A5955_RS02150	COG1286	toxin biosynthetic process
A5955_RS02155	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
A5955_RS02160	COG0285	dihydrofolate synthase activity
A5955_RS02170	COG0586	Pfam SNARE associated Golgi protein
A5955_RS02180	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A5955_RS02195	COG2814	Major facilitator Superfamily
A5955_RS02200	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A5955_RS02205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A5955_RS02205	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
A5955_RS02215	COG3101	peptidyl-lysine hydroxylation
A5955_RS02220	COG0730	response to heat
A5955_RS02250	COG3539	Fimbrial protein
A5955_RS02255	COG3539	Fimbrial protein
A5955_RS02260	COG3539	Fimbrial protein
A5955_RS02265	COG3121	Chaperone
A5955_RS02270	COG3188	usher protein
A5955_RS02275	COG3539	Fimbrial protein
A5955_RS02280	COG2062	phosphohistidine phosphatase, SixA
A5955_RS02295	COG3691	Protein conserved in bacteria
A5955_RS02300	COG2067	long-chain fatty acid transport protein
A5955_RS02310	COG2853	Lipoprotein
A5955_RS02315	COG2116	formate transmembrane transporter activity
A5955_RS02465	COG3772	lysozyme
A5955_RS02600	COG2815	serine threonine protein kinase
A5955_RS02600	COG0515	serine threonine protein kinase
A5955_RS02700	COG0582	viral genome integration into host DNA
A5955_RS02770	COG2610	gluconate transmembrane transporter activity
A5955_RS02780	COG0477	Major facilitator Superfamily
A5955_RS02785	COG1566	PFAM secretion protein HlyD family protein
A5955_RS02790	COG2197	response regulator
A5955_RS02795	COG0784	Response regulator, receiver
A5955_RS02795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A5955_RS02795	COG2198	Histidine kinase
A5955_RS02795	COG2205	protein histidine kinase activity
A5955_RS02800	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A5955_RS02805	COG0679	Auxin Efflux Carrier
A5955_RS02810	COG0028	Belongs to the TPP enzyme family
A5955_RS02840	COG1560	Kdo2-lipid A biosynthetic process
A5955_RS02845	COG0436	Aminotransferase
A5955_RS02850	COG3275	phosphorelay sensor kinase activity
A5955_RS02855	COG3279	Response regulator of the LytR AlgR family
A5955_RS02860	COG2207	Transcriptional regulator
A5955_RS02865	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A5955_RS02865	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A5955_RS02865	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A5955_RS02870	COG1363	Peptidase, m42
A5955_RS02875	COG0006	proline dipeptidase activity
A5955_RS02880	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A5955_RS02885	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A5955_RS02915	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A5955_RS02920	COG2199	diguanylate cyclase activity
A5955_RS02920	COG2200	EAL domain
A5955_RS02935	COG3415	Transposase
A5955_RS02940	COG3415	Transposase
A5955_RS02985	COG0583	DNA-binding transcription factor activity
A5955_RS02990	COG0385	Bile acid
A5955_RS02995	COG3530	Putative quorum-sensing-regulated virulence factor
A5955_RS03015	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A5955_RS03020	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A5955_RS03025	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A5955_RS03030	COG2190	(PTS) system
A5955_RS03045	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A5955_RS03050	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
A5955_RS03055	COG4208	sulfate ABC transporter
A5955_RS03060	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
A5955_RS03065	COG4150	thiosulfate binding
A5955_RS03070	COG1028	Short-chain dehydrogenase reductase Sdr
A5955_RS03085	COG1263	PTS System
A5955_RS03085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A5955_RS03090	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A5955_RS03095	COG2837	iron assimilation
A5955_RS03115	COG0860	N-Acetylmuramoyl-L-alanine amidase
A5955_RS03125	COG2207	Transcriptional regulator
A5955_RS03130	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
A5955_RS03135	COG4816	utilization protein
A5955_RS03145	COG4303	Ethanolamine ammonia lyase large subunit
A5955_RS03150	COG4819	ethanolamine utilization protein
A5955_RS03155	COG3192	ethanolamine utilization protein
A5955_RS03160	COG1454	alcohol dehydrogenase
A5955_RS03165	COG4820	ethanolamine utilization protein (EutJ)
A5955_RS03170	COG1012	belongs to the aldehyde dehydrogenase family
A5955_RS03175	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
A5955_RS03180	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
A5955_RS03185	COG0280	phosphate acetyltransferase
A5955_RS03190	COG4812	Cobalamin adenosyltransferase
A5955_RS03195	COG4766	ethanolamine catabolic process
A5955_RS03200	COG4917	ethanolamine utilization protein
A5955_RS03205	COG4810	utilization protein
A5955_RS03210	COG0281	malic enzyme
A5955_RS03210	COG0280	phosphate acetyltransferase
A5955_RS03215	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A5955_RS03220	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
A5955_RS03225	COG5342	invasion associated locus B
A5955_RS03235	COG0493	'glutamate synthase
A5955_RS03235	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A5955_RS03240	COG3850	Histidine kinase
A5955_RS03245	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A5955_RS03255	COG1393	Belongs to the ArsC family
A5955_RS03270	COG0400	carboxylic ester hydrolase activity
A5955_RS03280	COG2321	neutral zinc metallopeptidase
A5955_RS03295	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
A5955_RS03305	COG2716	regulation of RNA biosynthetic process
A5955_RS03310	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A5955_RS03315	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A5955_RS03320	COG0651	ATP synthesis coupled electron transport
A5955_RS03325	COG0650	Formate hydrogenlyase subunit 4
A5955_RS03330	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A5955_RS03335	COG4237	Hydrogenase 4 membrane
A5955_RS03340	COG0651	ATP synthesis coupled electron transport
A5955_RS03345	COG3261	NADH dehydrogenase
A5955_RS03345	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
A5955_RS03350	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A5955_RS03355	COG3260	NADH ubiquinone oxidoreductase 20
A5955_RS03365	COG3604	Transcriptional regulator
A5955_RS03370	COG2116	formate transmembrane transporter activity
A5955_RS03375	COG0628	permease
A5955_RS03380	COG4783	chaperone-mediated protein folding
A5955_RS03385	COG1393	Belongs to the ArsC family
A5955_RS03395	COG2233	PERMEase
A5955_RS03410	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
A5955_RS03415	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
A5955_RS03420	COG0248	Ppx GppA phosphatase
A5955_RS03425	COG2200	EAL domain
A5955_RS03440	COG3133	Outer membrane lipoprotein
A5955_RS03455	COG0516	GMP reductase activity
A5955_RS03455	COG0517	IMP dehydrogenase activity
A5955_RS03465	COG1645	bacterial-type flagellum-dependent swarming motility
A5955_RS03480	COG2976	Protein conserved in bacteria
A5955_RS03515	COG3302	dmso reductase anchor subunit
A5955_RS03520	COG0437	4 iron, 4 sulfur cluster binding
A5955_RS03525	COG0243	molybdopterin cofactor binding
A5955_RS03530	COG4953	penicillin-binding protein 1C
A5955_RS03535	COG2373	Large extracellular alpha-helical protein
A5955_RS03540	COG2897	thiosulfate sulfurtransferase activity
A5955_RS03555	COG2975	iron-sulfur cluster assembly
A5955_RS03560	COG0633	Ferredoxin
A5955_RS03580	COG0822	iron-sulfur transferase activity
A5955_RS03600	COG0483	inositol monophosphate 1-phosphatase activity
A5955_RS03605	COG1073	alpha beta
A5955_RS03610	COG3711	transcriptional antiterminator
A5955_RS03615	COG2814	Major facilitator Superfamily
A5955_RS03620	COG0583	DNA-binding transcription factor activity
A5955_RS03625	COG4638	Rieske (2fe-2S)
A5955_RS03650	COG2259	Doxx family
A5955_RS03655	COG2017	converts alpha-aldose to the beta-anomer
A5955_RS03660	COG1063	alcohol dehydrogenase
A5955_RS03665	COG1172	Belongs to the binding-protein-dependent transport system permease family
A5955_RS03670	COG1129	ABC transporter
A5955_RS03675	COG1879	ABC-type sugar transport system periplasmic component
A5955_RS03680	COG0457	Tetratricopeptide repeat
A5955_RS03685	COG1940	carbohydrate kinase activity
A5955_RS03695	COG1017	nitric oxide dioxygenase activity
A5955_RS03695	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A5955_RS03700	COG0347	Belongs to the P(II) protein family
A5955_RS03705	COG2204	response regulator
A5955_RS03710	COG3170	Tfp pilus assembly protein FimV
A5955_RS03715	COG2205	protein histidine kinase activity
A5955_RS03720	COG0047	phosphoribosylformylglycinamidine synthase activity
A5955_RS03720	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A5955_RS03730	COG0590	tRNA wobble adenosine to inosine editing
A5955_RS03735	COG0560	Phosphoserine phosphatase
A5955_RS03740	COG1737	Transcriptional regulator
A5955_RS03755	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
A5955_RS03770	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
A5955_RS03895	COG1783	phage Terminase large subunit
A5955_RS04005	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
A5955_RS04025	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
A5955_RS04045	COG0681	Belongs to the peptidase S26 family
A5955_RS04055	COG3086	response to oxidative stress
A5955_RS04060	COG3026	antisigma factor binding
A5955_RS04065	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
A5955_RS04070	COG1595	DNA-templated transcription, initiation
A5955_RS04080	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
A5955_RS04085	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
A5955_RS04090	COG0513	Belongs to the DEAD box helicase family
A5955_RS04095	COG0583	DNA-binding transcription factor activity
A5955_RS04100	COG1280	lysine exporter protein (LysE YggA)
A5955_RS04115	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A5955_RS04125	COG3118	belongs to the thioredoxin family
A5955_RS04130	COG3148	PFAM DTW domain containing protein
A5955_RS04135	COG1042	CoA-binding domain protein
A5955_RS04135	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A5955_RS04135	COG0045	succinate-CoA ligase (ADP-forming) activity
A5955_RS04140	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A5955_RS04145	COG5544	Lipoprotein
A5955_RS04150	COG0477	Major facilitator Superfamily
A5955_RS04180	COG0542	response to heat
A5955_RS04190	COG0564	pseudouridine synthase activity
A5955_RS04195	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A5955_RS04205	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
A5955_RS04210	COG0077	Prephenate dehydratase
A5955_RS04210	COG1605	Chorismate mutase
A5955_RS04215	COG0287	Prephenate dehydrogenase
A5955_RS04215	COG1605	Chorismate mutase
A5955_RS04220	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A5955_RS04235	COG2199	diguanylate cyclase activity
A5955_RS04240	COG2885	chlorophyll binding
A5955_RS04265	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A5955_RS04270	COG4137	Cytochrome C assembly protein
A5955_RS04275	COG4536	flavin adenine dinucleotide binding
A5955_RS04290	COG0497	DNA recombination
A5955_RS04295	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A5955_RS04305	COG2867	negative regulation of translational initiation
A5955_RS04320	COG0582	viral genome integration into host DNA
A5955_RS04475	COG0579	oxidoreductase
A5955_RS04480	COG1012	belongs to the aldehyde dehydrogenase family
A5955_RS04485	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A5955_RS04490	COG1113	amino acid transport
A5955_RS04495	COG1802	Transcriptional regulator
A5955_RS04500	COG1652	LysM domain
A5955_RS04505	COG0401	homolog of Blt101
A5955_RS04510	COG0640	Transcriptional regulator
A5955_RS04515	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A5955_RS04520	COG2916	Histone family protein nucleoid-structuring protein H-NS
A5955_RS04535	COG4575	ribosome binding
A5955_RS04545	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A5955_RS04550	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
A5955_RS04560	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A5955_RS04565	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A5955_RS04570	COG4175	Glycine betaine
A5955_RS04575	COG4176	ABC-type proline glycine betaine transport system permease component
A5955_RS04580	COG2113	Glycine betaine
A5955_RS04585	COG2814	Major facilitator Superfamily
A5955_RS04590	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
A5955_RS04600	COG1846	Transcriptional regulator
A5955_RS04605	COG1566	PFAM secretion protein HlyD family protein
A5955_RS04610	COG2814	Major facilitator Superfamily
A5955_RS04625	COG1238	metal cluster binding
A5955_RS04630	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A5955_RS04660	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
A5955_RS04665	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A5955_RS04685	COG1546	Belongs to the CinA family
A5955_RS04690	COG2951	lytic endotransglycosylase activity
A5955_RS04695	COG3730	PTS system glucitol sorbitol-specific
A5955_RS04700	COG3732	PTS system glucitol sorbitol-specific
A5955_RS04710	COG1028	Short-chain dehydrogenase reductase Sdr
A5955_RS04715	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
A5955_RS04720	COG1349	DNA-binding transcription factor activity
A5955_RS04725	COG0517	IMP dehydrogenase activity
A5955_RS04725	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
A5955_RS04745	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
A5955_RS04750	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A5955_RS04755	COG1609	Transcriptional regulator
A5955_RS04760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A5955_RS04760	COG1263	PTS System
A5955_RS04765	COG2723	6-phospho-beta-galactosidase activity
A5955_RS04770	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
A5955_RS04780	COG3260	NADH ubiquinone oxidoreductase 20
A5955_RS04785	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A5955_RS04790	COG3261	NADH dehydrogenase
A5955_RS04790	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
A5955_RS04795	COG0650	Formate hydrogenlyase subunit 4
A5955_RS04800	COG0651	ATP synthesis coupled electron transport
A5955_RS04805	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A5955_RS04820	COG0375	protein maturation
A5955_RS04825	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
A5955_RS04830	COG0298	carbon dioxide binding
A5955_RS04835	COG0409	Hydrogenase expression formation protein
A5955_RS04840	COG0309	Hydrogenase expression formation protein (HypE)
A5955_RS04845	COG3604	Transcriptional regulator
A5955_RS04860	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
A5955_RS04870	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
A5955_RS04875	COG0163	prenyltransferase activity
A5955_RS04885	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A5955_RS04890	COG1388	LysM domain
A5955_RS04890	COG4942	peptidase
A5955_RS04945	COG2234	aminopeptidase activity
A5955_RS04950	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A5955_RS04955	COG1518	maintenance of DNA repeat elements
A5955_RS04970	COG1857	crispr-associated protein
A5955_RS04985	COG1203	CRISPR-associated helicase, Cas3
A5955_RS05005	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
A5955_RS05010	COG0720	synthase
A5955_RS05015	COG0644	oxidoreductase
A5955_RS05020	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
A5955_RS05025	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
A5955_RS05030	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
A5955_RS05035	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
A5955_RS05040	COG2086	electron transfer activity
A5955_RS05045	COG0477	Major facilitator Superfamily
A5955_RS05050	COG0277	FAD linked oxidase domain protein
A5955_RS05055	COG1028	Short-chain dehydrogenase reductase Sdr
A5955_RS05060	COG2223	nitrite transmembrane transporter activity
A5955_RS05065	COG2223	nitrite transmembrane transporter activity
A5955_RS05070	COG1070	Carbohydrate kinase
A5955_RS05075	COG0602	queuosine metabolic process
A5955_RS05085	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
A5955_RS05095	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
A5955_RS05110	COG3956	TIGRFAM MazG family protein
A5955_RS05115	COG2337	Toxic component of a toxin-antitoxin (TA) module
A5955_RS05120	COG2336	PFAM SpoVT AbrB
A5955_RS05125	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A5955_RS05130	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A5955_RS05135	COG2205	protein histidine kinase activity
A5955_RS05135	COG3437	response regulator, receiver
A5955_RS05135	COG4999	Histidine kinase
A5955_RS05135	COG3850	Histidine kinase
A5955_RS05140	COG4948	Mandelate Racemase Muconate Lactonizing
A5955_RS05145	COG4948	Mandelate Racemase Muconate Lactonizing
A5955_RS05150	COG2271	Major facilitator Superfamily
A5955_RS05155	COG0716	FMN binding
A5955_RS05160	COG0564	pseudouridine synthase activity
A5955_RS05165	COG3098	single-species biofilm formation
A5955_RS05185	COG1611	Belongs to the LOG family
A5955_RS05190	COG0814	amino acid
A5955_RS05195	COG1760	l-serine dehydratase
A5955_RS05205	COG1454	alcohol dehydrogenase
A5955_RS05210	COG0235	Class ii aldolase
A5955_RS05215	COG0738	Major facilitator superfamily
A5955_RS05225	COG1070	Carbohydrate kinase
A5955_RS05235	COG1349	DNA-binding transcription factor activity
A5955_RS05245	COG2363	Small membrane protein
A5955_RS05250	COG0583	DNA-binding transcription factor activity
A5955_RS05260	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A5955_RS05265	COG2166	iron-sulfur cluster assembly
A5955_RS05270	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
A5955_RS05275	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
A5955_RS05295	COG0860	N-Acetylmuramoyl-L-alanine amidase
A5955_RS05300	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
A5955_RS05300	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
A5955_RS05305	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A5955_RS05310	COG1074	ATP-dependent DNA helicase activity
A5955_RS05315	COG1025	Belongs to the peptidase M16 family
A5955_RS05320	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
A5955_RS05325	COG4967	type IV pilus modification protein PilV
A5955_RS05335	COG4795	General secretion pathway protein
A5955_RS05340	COG2165	general secretion pathway protein
A5955_RS05355	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
A5955_RS05380	COG0861	Integral membrane protein TerC family
A5955_RS05390	COG0667	Aldo Keto reductase
A5955_RS05405	COG1609	Transcriptional regulator
A5955_RS05415	COG0583	DNA-binding transcription factor activity
A5955_RS05420	COG1794	racemase activity, acting on amino acids and derivatives
A5955_RS05425	COG2814	Major facilitator Superfamily
A5955_RS05430	COG1028	Short-chain dehydrogenase reductase Sdr
A5955_RS05440	COG0183	Belongs to the thiolase family
A5955_RS05445	COG0814	amino acid
A5955_RS05450	COG2771	luxR family
A5955_RS05455	COG3710	Transcriptional regulator
A5955_RS05485	COG0457	Tetratricopeptide repeat
A5955_RS05495	COG3710	Transcriptional regulator
A5955_RS05495	COG0457	Tetratricopeptide repeat
A5955_RS05515	COG2207	Transcriptional regulator
A5955_RS05535	COG4942	peptidase
A5955_RS05540	COG1529	Aldehyde oxidase and xanthine dehydrogenase
A5955_RS05545	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
A5955_RS05550	COG2080	2 iron, 2 sulfur cluster binding
A5955_RS05555	COG3829	transcription factor binding
A5955_RS05560	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
A5955_RS05565	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A5955_RS05570	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A5955_RS05580	COG0549	Belongs to the carbamate kinase family
A5955_RS05585	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
A5955_RS05585	COG3608	succinylglutamate desuccinylase aspartoacylase
A5955_RS05590	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
A5955_RS05595	COG2068	MobA-Related Protein
A5955_RS05600	COG0493	'glutamate synthase
A5955_RS05600	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
A5955_RS05605	COG0402	S-adenosylhomocysteine deaminase activity
A5955_RS05610	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
A5955_RS05615	COG1529	Aldehyde oxidase and xanthine dehydrogenase
A5955_RS05615	COG2080	2 iron, 2 sulfur cluster binding
A5955_RS05620	COG2233	PERMEase
A5955_RS05625	COG0402	S-adenosylhomocysteine deaminase activity
A5955_RS05630	COG2252	PERMEase
A5955_RS05635	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A5955_RS05640	COG0493	'glutamate synthase
A5955_RS05640	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A5955_RS05650	COG2233	PERMEase
A5955_RS05665	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
A5955_RS05675	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A5955_RS05680	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A5955_RS05685	COG4974	Belongs to the 'phage' integrase family
A5955_RS05690	COG0716	FMN binding
A5955_RS05700	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
A5955_RS05710	COG1272	protein, Hemolysin III
A5955_RS05720	COG2723	6-phospho-beta-galactosidase activity
A5955_RS05740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A5955_RS05745	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A5955_RS05750	COG0006	proline dipeptidase activity
A5955_RS05770	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A5955_RS05780	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A5955_RS05795	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A5955_RS05795	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A5955_RS05800	COG1703	isobutyryl-CoA mutase activity
A5955_RS05805	COG1024	Enoyl-CoA hydratase
A5955_RS05810	COG0427	acetyl-CoA hydrolase
A5955_RS05815	COG0583	DNA-binding transcription factor activity
A5955_RS05820	COG0583	DNA-binding transcription factor activity
A5955_RS05825	COG2968	Membrane
A5955_RS05835	COG0668	transmembrane transport
A5955_RS05840	COG0191	fructose-bisphosphate aldolase activity
A5955_RS05845	COG0126	phosphoglycerate kinase activity
A5955_RS05870	COG1122	ATPase activity
A5955_RS05875	COG1122	ATPase activity
A5955_RS05880	COG1072	(Pantothenic acid kinase))
A5955_RS05890	COG1494	fructose-1,6-bisphosphatase
A5955_RS05895	COG1063	alcohol dehydrogenase
A5955_RS05900	COG2213	PTS system mannitol-specific
A5955_RS05905	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A5955_RS05910	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
A5955_RS05915	COG0501	Belongs to the peptidase M48B family
A5955_RS05930	COG1166	arginine decarboxylase activity
A5955_RS05955	COG2814	Major facilitator Superfamily
A5955_RS05965	COG2356	endonuclease I
A5955_RS05970	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A5955_RS05975	COG0189	ligase activity
A5955_RS05990	COG2805	Type II/IV secretion system protein
A5955_RS05995	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
A5955_RS06000	COG0762	integral membrane protein
A5955_RS06010	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
A5955_RS06015	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A5955_RS06025	COG0252	asparaginase activity
A5955_RS06040	COG3171	Protein conserved in bacteria
A5955_RS06050	COG1194	a g-specific adenine glycosylase
A5955_RS06065	COG2211	Major facilitator Superfamily
A5955_RS06070	COG1982	Orn Lys Arg decarboxylase major
A5955_RS06075	COG1811	Na channel or pump
A5955_RS06085	COG0582	viral genome integration into host DNA
A5955_RS06090	COG4372	Transposase
A5955_RS06100	COG3436	PFAM IS66 Orf2 family protein
A5955_RS06105	COG2433	Pfam Transposase IS66
A5955_RS06180	COG3436	PFAM IS66 Orf2 family protein
A5955_RS06190	COG4372	Transposase
A5955_RS06260	COG2003	Belongs to the UPF0758 family
A5955_RS06285	COG4584	PFAM Integrase catalytic
A5955_RS06290	COG1484	DNA-dependent DNA replication
A5955_RS06310	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
A5955_RS06340	COG2165	general secretion pathway protein
A5955_RS06345	COG1459	type II secretion system
A5955_RS06350	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A5955_RS06360	COG3031	protein transport across the cell outer membrane
A5955_RS06375	COG3064	Membrane
A5955_RS06385	COG1620	l-lactate permease
A5955_RS06390	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
A5955_RS06395	COG3193	protein, possibly involved in utilization of glycolate and propanediol
A5955_RS06400	COG0247	lactate metabolic process
A5955_RS06405	COG0277	FAD linked oxidase domain protein
A5955_RS06410	COG0277	FAD linked oxidase domain protein
A5955_RS06415	COG2186	Transcriptional regulator
A5955_RS06420	COG0456	acetyltransferase
A5955_RS06425	COG0318	PFAM AMP-dependent synthetase and ligase
A5955_RS06435	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A5955_RS06440	COG0156	8-amino-7-oxononanoate synthase activity
A5955_RS06450	COG0795	lipopolysaccharide-transporting ATPase activity
A5955_RS06455	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
A5955_RS06465	COG2244	polysaccharide biosynthetic process
A5955_RS06470	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
A5955_RS06475	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
A5955_RS06485	COG0306	phosphate transporter
A5955_RS06490	COG0754	glutathionylspermidine amidase activity
A5955_RS06495	COG0625	glutathione transferase activity
A5955_RS06500	COG0298	carbon dioxide binding
A5955_RS06505	COG0375	protein maturation
A5955_RS06510	COG1773	rubredoxin
A5955_RS06515	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
A5955_RS06520	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
A5955_RS06525	COG5557	Pfam Polysulphide reductase, NrfD
A5955_RS06530	COG0437	4 iron, 4 sulfur cluster binding
A5955_RS06535	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
A5955_RS06555	COG0667	Aldo Keto reductase
A5955_RS06565	COG1028	Short-chain dehydrogenase reductase Sdr
A5955_RS06570	COG0848	biopolymer transport protein
A5955_RS06575	COG0811	peptide transport
A5955_RS06585	COG0626	cystathionine gamma-synthase activity
A5955_RS06590	COG0586	Pfam SNARE associated Golgi protein
A5955_RS06595	COG2207	Transcriptional regulator
A5955_RS06605	COG1979	alcohol dehydrogenase
A5955_RS06610	COG0656	L-ascorbic acid biosynthetic process
A5955_RS06620	COG4238	major outer membrane lipoprotein
A5955_RS06625	COG1032	radical SAM domain protein
A5955_RS06630	COG2132	Multicopper oxidase
A5955_RS06635	COG0204	Acyl-transferase
A5955_RS06640	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A5955_RS06645	COG4166	transmembrane transport
A5955_RS06650	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
A5955_RS06655	COG3111	PFAM Bacterial OB fold (BOF) protein
A5955_RS06660	COG0745	RESPONSE REGULATOR receiver
A5955_RS06665	COG0642	Histidine kinase
A5955_RS06670	COG2249	NAD(P)H dehydrogenase (quinone) activity
A5955_RS06675	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
A5955_RS06680	COG1737	Transcriptional regulator
A5955_RS06690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A5955_RS06695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A5955_RS06700	COG1120	ATPase activity
A5955_RS06705	COG4774	siderophore transport
A5955_RS06710	COG0187	DNA topoisomerase II activity
A5955_RS06715	COG3150	esterase
A5955_RS06720	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
A5955_RS06725	COG3151	Protein conserved in bacteria
A5955_RS06730	COG0494	nUDIX hydrolase
A5955_RS06735	COG1538	Outer membrane efflux protein
A5955_RS06750	COG0754	glutathionylspermidine amidase activity
A5955_RS06755	COG3384	dioxygenase
A5955_RS06785	COG1585	Membrane protein implicated in regulation of membrane protease activity
A5955_RS06790	COG2268	Band 7 protein
A5955_RS06815	COG3025	triphosphatase activity
A5955_RS06825	COG4991	sh3 domain protein
A5955_RS06840	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
A5955_RS06850	COG0583	DNA-binding transcription factor activity
A5955_RS06855	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
A5955_RS06860	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
A5955_RS06865	COG0471	metal ion transport
A5955_RS06875	COG0828	Belongs to the bacterial ribosomal protein bS21 family
A5955_RS06880	COG0358	DNA primase activity
A5955_RS06885	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A5955_RS06900	COG2375	cellular response to nickel ion
A5955_RS06905	COG1695	Transcriptional regulator
A5955_RS06910	COG0840	transmembrane signaling receptor activity
A5955_RS06920	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A5955_RS06925	COG1609	Transcriptional regulator
A5955_RS06930	COG3250	beta-galactosidase activity
A5955_RS06935	COG2731	YhcH YjgK YiaL family protein
A5955_RS06940	COG0531	amino acid
A5955_RS06950	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
A5955_RS06950	COG3408	Glycogen debranching enzyme
A5955_RS06955	COG0446	pyridine nucleotide-disulphide oxidoreductase
A5955_RS06955	COG1902	pentaerythritol trinitrate reductase activity
A5955_RS06960	COG5499	transcription regulator containing HTH domain
A5955_RS06965	COG4680	protein conserved in bacteria
A5955_RS06980	COG1451	nucleotide metabolic process
A5955_RS06985	COG2949	membrane
A5955_RS06990	COG0673	inositol 2-dehydrogenase activity
A5955_RS06995	COG0861	Integral membrane protein TerC family
A5955_RS07000	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
A5955_RS07010	COG2721	sulfolactate sulfo-lyase activity
A5955_RS07020	COG2271	Major facilitator Superfamily
A5955_RS07025	COG2186	Transcriptional regulator
A5955_RS07030	COG0586	Pfam SNARE associated Golgi protein
A5955_RS07040	COG1422	Protein of unknown function (DUF1090)
A5955_RS07045	COG4575	ribosome binding
A5955_RS07050	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
A5955_RS07060	COG2259	Doxx family
A5955_RS07065	COG0435	Glutathione S-transferase
A5955_RS07070	COG3152	Membrane
A5955_RS07075	COG3152	Membrane
A5955_RS07080	COG0583	DNA-binding transcription factor activity
A5955_RS07085	COG1741	Belongs to the pirin family
A5955_RS07100	COG0814	amino acid
A5955_RS07105	COG1760	l-serine dehydratase
A5955_RS07110	COG0251	oxidation-reduction process
A5955_RS07115	COG1882	Formate acetyltransferase
A5955_RS07120	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
A5955_RS07130	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A5955_RS07135	COG0583	DNA-binding transcription factor activity
A5955_RS07160	COG1929	Belongs to the glycerate kinase type-1 family
A5955_RS07165	COG2084	Dehydrogenase
A5955_RS07175	COG2271	Major facilitator Superfamily
A5955_RS07180	COG2721	sulfolactate sulfo-lyase activity
A5955_RS07185	COG2002	toxin-antitoxin pair type II binding
A5955_RS07195	COG1349	DNA-binding transcription factor activity
A5955_RS07205	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A5955_RS07215	COG3716	PTS system mannose fructose sorbose family IID component
A5955_RS07220	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
A5955_RS07225	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A5955_RS07230	COG2222	sugar isomerase
A5955_RS07240	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A5955_RS07245	COG3715	PTS system
A5955_RS07250	COG3716	PTS system mannose fructose sorbose family IID component
A5955_RS07260	COG3539	Fimbrial protein
A5955_RS07265	COG3121	Chaperone
A5955_RS07270	COG3188	usher protein
A5955_RS07275	COG3539	Fimbrial protein
A5955_RS07280	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
A5955_RS07300	COG2823	Periplasmic or secreted lipoprotein
A5955_RS07305	COG0701	Predicted permease
A5955_RS07310	COG0702	epimerase
A5955_RS07315	COG0693	protein deglycase activity
A5955_RS07320	COG3787	Belongs to the UPF0306 family
A5955_RS07330	COG3153	acetyltransferase
A5955_RS07335	COG3154	lipid carrier protein
A5955_RS07340	COG0826	peptidase U32
A5955_RS07345	COG0826	peptidase U32
A5955_RS07350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A5955_RS07355	COG0814	amino acid
A5955_RS07365	COG0513	Belongs to the DEAD box helicase family
A5955_RS07400	COG0195	Participates in both transcription termination and antitermination
A5955_RS07420	COG2194	sulfuric ester hydrolase activity
A5955_RS07430	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A5955_RS07440	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A5955_RS07445	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A5955_RS07455	COG1534	Rna-binding protein
A5955_RS07460	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A5955_RS07465	COG2027	D-alanyl-D-alanine carboxypeptidase
A5955_RS07475	COG0697	spore germination
A5955_RS07490	COG0142	geranyltranstransferase activity
A5955_RS07495	COG3423	Transcriptional regulator
A5955_RS07505	COG5007	Belongs to the BolA IbaG family
A5955_RS07510	COG3113	response to antibiotic
A5955_RS07515	COG2854	intermembrane phospholipid transfer
A5955_RS07520	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
A5955_RS07525	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A5955_RS07530	COG1127	ABC transporter
A5955_RS07535	COG0530	calcium, potassium:sodium antiporter activity
A5955_RS07540	COG0517	IMP dehydrogenase activity
A5955_RS07540	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
A5955_RS07545	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
A5955_RS07550	COG3117	lipopolysaccharide transmembrane transporter activity
A5955_RS07555	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
A5955_RS07560	COG1137	ATPase activity
A5955_RS07565	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
A5955_RS07570	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
A5955_RS07585	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A5955_RS07590	COG0515	serine threonine protein kinase
A5955_RS07600	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
A5955_RS07605	COG2198	Histidine kinase
A5955_RS07605	COG5002	protein histidine kinase activity
A5955_RS07605	COG0784	Response regulator, receiver
A5955_RS07610	COG1242	4 iron, 4 sulfur cluster binding
A5955_RS07615	COG0069	glutamate synthase activity
A5955_RS07615	COG0067	glutamate synthase
A5955_RS07615	COG0070	glutamate synthase
A5955_RS07620	COG0493	'glutamate synthase
A5955_RS07625	COG4804	nuclease activity
A5955_RS07630	COG2731	YhcH YjgK YiaL family protein
A5955_RS07660	COG3069	C4-dicarboxylate transmembrane transporter activity
A5955_RS07665	COG2969	positive regulation of protein catabolic process
A5955_RS07670	COG0625	glutathione transferase activity
A5955_RS07685	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
A5955_RS07690	COG3105	Protein conserved in bacteria
A5955_RS07695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A5955_RS07700	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A5955_RS07720	COG2732	(Barnase) inhibitor
A5955_RS07740	COG0583	DNA-binding transcription factor activity
A5955_RS07745	COG0312	modulator of DNA gyrase
A5955_RS07750	COG3164	Protein of unknown function
A5955_RS07755	COG1530	ribonuclease E activity
A5955_RS07760	COG0424	maF-like protein
A5955_RS07765	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
A5955_RS07770	COG1792	Involved in formation and maintenance of cell shape
A5955_RS07775	COG1077	Cell shape determining protein MreB Mrl
A5955_RS07785	COG2199	diguanylate cyclase activity
A5955_RS07785	COG2200	EAL domain
A5955_RS07790	COG0604	alcohol dehydrogenase
A5955_RS07810	COG0511	ligase activity, forming carbon-carbon bonds
A5955_RS07815	COG0439	Biotin carboxylase
A5955_RS07820	COG3924	membrane
A5955_RS07825	COG4145	pantothenate transmembrane transporter activity
A5955_RS07835	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A5955_RS07845	COG2189	Belongs to the N(4) N(6)-methyltransferase family
A5955_RS07855	COG1309	transcriptional regulator
A5955_RS07860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A5955_RS07865	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A5955_RS07880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A5955_RS07885	COG4597	amino acid ABC transporter
A5955_RS07890	COG0765	amino acid transport
A5955_RS07895	COG1126	abc transporter atp-binding protein
A5955_RS07935	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
A5955_RS07950	COG0009	L-threonylcarbamoyladenylate synthase
A5955_RS07955	COG0551	DNA topoisomerase type I activity
A5955_RS07965	COG0758	DNA mediated transformation
A5955_RS07985	COG0569	domain protein
A5955_RS07995	COG3036	rescue of stalled ribosome
A5955_RS08000	COG0789	Transcriptional regulator
A5955_RS08040	COG0201	protein transport
A5955_RS08130	COG0089	rRNA binding
A5955_RS08205	COG2964	Protein conserved in bacteria
A5955_RS08210	COG0545	Peptidyl-prolyl cis-trans isomerase
A5955_RS08220	COG1047	Peptidyl-prolyl cis-trans
A5955_RS08225	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
A5955_RS08240	COG0488	(ABC) transporter
A5955_RS08245	COG0429	hydrolase of the alpha beta-hydrolase fold
A5955_RS08255	COG3954	Phosphoribulokinase
A5955_RS08260	COG1765	OsmC-like protein
A5955_RS08270	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A5955_RS08275	COG1289	transmembrane transporter activity
A5955_RS08280	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A5955_RS08285	COG0512	Glutamine amidotransferase of anthranilate synthase
A5955_RS08290	COG2184	nucleotidyltransferase activity
A5955_RS08300	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A5955_RS08310	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A5955_RS08315	COG2146	nitrite reductase [NAD(P)H] activity
A5955_RS08320	COG2116	formate transmembrane transporter activity
A5955_RS08335	COG0531	amino acid
A5955_RS08340	COG2222	sugar isomerase
A5955_RS08345	COG1082	Xylose isomerase domain protein TIM barrel
A5955_RS08350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A5955_RS08355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A5955_RS08360	COG2188	Transcriptional regulator
A5955_RS08365	COG0180	Tryptophanyl-tRNA synthetase
A5955_RS08370	COG0546	phosphoglycolate phosphatase activity
A5955_RS08375	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A5955_RS08380	COG0338	D12 class N6 adenine-specific DNA methyltransferase
A5955_RS08385	COG3266	domain, Protein
A5955_RS08400	COG4796	Type ii and iii secretion system protein
A5955_RS08415	COG3166	PFAM Fimbrial assembly family protein
A5955_RS08420	COG4972	Pilus assembly protein
A5955_RS08425	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
A5955_RS08430	COG0494	nUDIX hydrolase
A5955_RS08440	COG1011	Hydrolase
A5955_RS08445	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
A5955_RS08455	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
A5955_RS08480	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A5955_RS08485	COG2183	response to ionizing radiation
A5955_RS08490	COG1918	ferrous iron import across plasma membrane
A5955_RS08495	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
A5955_RS08505	COG5464	transposase or invertase
A5955_RS08515	COG1040	competence protein
A5955_RS08525	COG2610	gluconate transmembrane transporter activity
A5955_RS08530	COG1640	4-alpha-glucanotransferase
A5955_RS08535	COG0058	SHG alpha-glucan phosphorylase activity
A5955_RS08560	COG1690	Belongs to the RtcB family
A5955_RS08565	COG4650	regulator
A5955_RS08570	COG1349	DNA-binding transcription factor activity
A5955_RS08585	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
A5955_RS08600	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A5955_RS08605	COG0058	SHG alpha-glucan phosphorylase activity
A5955_RS08625	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
A5955_RS08630	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A5955_RS08635	COG2095	MarC family integral membrane protein
A5955_RS08650	COG2610	gluconate transmembrane transporter activity
A5955_RS08655	COG3265	gluconokinase activity
A5955_RS08660	COG1609	Transcriptional regulator
A5955_RS08665	COG1741	Belongs to the pirin family
A5955_RS08670	COG0673	inositol 2-dehydrogenase activity
A5955_RS08675	COG1247	-acetyltransferase
A5955_RS08690	COG0405	Gamma-glutamyltransferase
A5955_RS08700	COG0584	glycerophosphoryl diester phosphodiesterase
A5955_RS08715	COG1175	transmembrane transport
A5955_RS08720	COG1653	transport
A5955_RS08730	COG0410	ABC transporter
A5955_RS08735	COG0411	ABC transporter
A5955_RS08740	COG4177	L-phenylalanine transmembrane transporter activity
A5955_RS08745	COG0559	Belongs to the binding-protein-dependent transport system permease family
A5955_RS08750	COG0683	leucine binding
A5955_RS08755	COG0456	acetyltransferase
A5955_RS08770	COG0683	leucine binding
A5955_RS08775	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A5955_RS08780	COG2177	Part of the ABC transporter FtsEX involved in
A5955_RS08785	COG2884	Cell division ATP-binding protein ftsE
A5955_RS08790	COG0552	protein localization to endoplasmic reticulum
A5955_RS08795	COG0742	ribosomal rna small subunit methyltransferase
A5955_RS08800	COG3776	membrane
A5955_RS08810	COG3714	YhhN family
A5955_RS08825	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
A5955_RS08840	COG0628	permease
A5955_RS08860	COG0204	Acyl-transferase
A5955_RS08870	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A5955_RS08890	COG1216	Glycosyl transferase, family 2
A5955_RS08915	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A5955_RS08925	COG1028	Short-chain dehydrogenase reductase Sdr
A5955_RS08930	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A5955_RS08935	COG2091	lysine biosynthetic process via aminoadipic acid
A5955_RS08940	COG0747	negative chemotaxis
A5955_RS08945	COG0601	transmembrane transport
A5955_RS08950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A5955_RS08955	COG0444	Belongs to the ABC transporter superfamily
A5955_RS08960	COG1124	(ABC) transporter
A5955_RS08970	COG2188	Transcriptional regulator
A5955_RS08980	COG3414	Phosphotransferase system galactitol-specific IIB component
A5955_RS08985	COG3775	system Galactitol-specific IIC component
A5955_RS09000	COG0191	fructose-bisphosphate aldolase activity
A5955_RS09015	COG0842	Transport permease protein
A5955_RS09020	COG1129	ABC transporter
A5955_RS09020	COG0842	Transport permease protein
A5955_RS09025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A5955_RS09055	COG2081	HI0933 family
A5955_RS09060	COG0306	phosphate transporter
A5955_RS09070	COG0589	response to stress
A5955_RS09075	COG3104	oligopeptide transport
A5955_RS09085	COG0339	signal peptide processing
A5955_RS09090	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
A5955_RS09095	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A5955_RS09110	COG0640	Transcriptional regulator
A5955_RS09115	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A5955_RS09120	COG1393	Belongs to the ArsC family
A5955_RS09130	COG3065	identical protein binding
A5955_RS09135	COG2197	response regulator
A5955_RS09140	COG3720	iron ion transport
A5955_RS09145	COG4771	TonB-dependent receptor
A5955_RS09155	COG4558	Periplasmic binding protein
A5955_RS09165	COG3721	Heme iron utilization protein
A5955_RS09175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A5955_RS09185	COG1285	pathogenesis
A5955_RS09200	COG3247	response to pH
A5955_RS09205	COG2771	luxR family
A5955_RS09215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A5955_RS09220	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A5955_RS09225	COG2207	Transcriptional regulator
A5955_RS09230	COG2207	Transcriptional regulator
A5955_RS09235	COG0076	glutamate decarboxylase activity
A5955_RS09240	COG1858	cytochrome C peroxidase
A5955_RS09250	COG2197	response regulator
A5955_RS09255	COG0583	DNA-binding transcription factor activity
A5955_RS09260	COG1295	ribonuclease BN
A5955_RS09265	COG0477	Major facilitator Superfamily
A5955_RS09270	COG2982	Protein involved in outer membrane biogenesis
A5955_RS09275	COG2200	EAL domain
A5955_RS09290	COG0612	Peptidase, M16
A5955_RS09300	COG2199	diguanylate cyclase activity
A5955_RS09300	COG2200	EAL domain
A5955_RS09305	COG3118	belongs to the thioredoxin family
A5955_RS09305	COG0457	Tetratricopeptide repeat
A5955_RS09310	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
A5955_RS09315	COG1215	transferase activity, transferring glycosyl groups
A5955_RS09320	COG1215	transferase activity, transferring glycosyl groups
A5955_RS09345	COG2194	sulfuric ester hydrolase activity
A5955_RS09360	COG0814	amino acid
A5955_RS09365	COG4608	Belongs to the ABC transporter superfamily
A5955_RS09370	COG0444	Belongs to the ABC transporter superfamily
A5955_RS09375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A5955_RS09380	COG0601	transmembrane transport
A5955_RS09390	COG0747	negative chemotaxis
A5955_RS09405	COG2194	sulfuric ester hydrolase activity
A5955_RS09410	COG3539	Fimbrial protein
A5955_RS09415	COG3539	Fimbrial protein
A5955_RS09425	COG3121	Chaperone
A5955_RS09430	COG3539	Fimbrial protein
A5955_RS09435	COG2223	nitrite transmembrane transporter activity
A5955_RS09440	COG5571	outer membrane autotransporter
A5955_RS09445	COG2818	Glycosylase
A5955_RS09450	COG0456	acetyltransferase
A5955_RS09455	COG0243	molybdopterin cofactor binding
A5955_RS09460	COG2885	chlorophyll binding
A5955_RS09475	COG2944	sequence-specific DNA binding
A5955_RS09480	COG1278	Cold shock
A5955_RS09505	COG3274	enterobacterial common antigen metabolic process
A5955_RS09510	COG4682	membrane
A5955_RS09515	COG4682	membrane
A5955_RS09520	COG1070	Carbohydrate kinase
A5955_RS09530	COG4213	ABC transporter substrate-binding protein
A5955_RS09540	COG4214	carbohydrate transport
A5955_RS09545	COG2207	Transcriptional regulator
A5955_RS09545	COG1609	Transcriptional regulator
A5955_RS09550	COG2992	FlgJ-related protein
A5955_RS09555	COG0366	Alpha amylase catalytic
A5955_RS09560	COG3977	Valine--pyruvate aminotransferase
A5955_RS09570	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A5955_RS09580	COG2211	Major facilitator Superfamily
A5955_RS09590	COG3713	MltA-interacting MipA family protein
A5955_RS09595	COG0583	DNA-binding transcription factor activity
A5955_RS09600	COG1566	PFAM secretion protein HlyD family protein
A5955_RS09615	COG1012	belongs to the aldehyde dehydrogenase family
A5955_RS09625	COG1454	alcohol dehydrogenase
A5955_RS09630	COG3276	selenocysteine insertion sequence binding
A5955_RS09640	COG0625	glutathione transferase activity
A5955_RS09645	COG3209	COG3209 Rhs family protein
A5955_RS09655	COG3209	COG3209 Rhs family protein
A5955_RS09660	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
A5955_RS09670	COG1566	PFAM secretion protein HlyD family protein
A5955_RS09680	COG2213	PTS system mannitol-specific
A5955_RS09680	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
A5955_RS09690	COG3722	fumarate hydratase activity
A5955_RS09710	COG5295	Hep Hag repeat protein
A5955_RS09715	COG1620	l-lactate permease
A5955_RS09720	COG2186	Transcriptional regulator
A5955_RS09730	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
A5955_RS09735	COG1045	serine acetyltransferase
A5955_RS09750	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
A5955_RS09755	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A5955_RS09765	COG4942	peptidase
A5955_RS09770	COG2861	carbohydrate metabolic process
A5955_RS09775	COG1216	Glycosyl transferase, family 2
A5955_RS09785	COG0156	8-amino-7-oxononanoate synthase activity
A5955_RS09800	COG0859	PFAM glycosyl transferase family 9
A5955_RS09805	COG0859	PFAM glycosyl transferase family 9
A5955_RS09825	COG3642	lipopolysaccharide core region biosynthetic process
A5955_RS09835	COG0515	serine threonine protein kinase
A5955_RS09840	COG0438	transferase activity, transferring glycosyl groups
A5955_RS09845	COG0859	PFAM glycosyl transferase family 9
A5955_RS09850	COG1519	Transferase
A5955_RS09880	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A5955_RS09905	COG1561	YicC-like family, N-terminal region
A5955_RS09910	COG3645	SOS response
A5955_RS09915	COG2860	membrane
A5955_RS09925	COG0194	GDP metabolic process
A5955_RS09935	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A5955_RS09940	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A5955_RS09945	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A5955_RS09955	COG0786	glutamate:sodium symporter activity
A5955_RS09960	COG2233	PERMEase
A5955_RS09965	COG2982	Protein involved in outer membrane biogenesis
A5955_RS09970	COG1501	Belongs to the glycosyl hydrolase 31 family
A5955_RS09975	COG2211	Major facilitator Superfamily
A5955_RS09985	COG0582	viral genome integration into host DNA
A5955_RS09990	COG2963	transposase activity
A5955_RS09995	COG2826	transposase and inactivated derivatives, IS30 family
A5955_RS10090	COG5492	domain, Protein
A5955_RS10260	COG0697	spore germination
A5955_RS10265	COG1464	Belongs to the NlpA lipoprotein family
A5955_RS10280	COG2814	Major facilitator Superfamily
A5955_RS10315	COG2271	Major facilitator Superfamily
A5955_RS10320	COG2271	Major facilitator Superfamily
A5955_RS10325	COG3851	Histidine kinase
A5955_RS10330	COG2197	response regulator
A5955_RS10350	COG0440	acetolactate synthase activity
A5955_RS10355	COG0028	Belongs to the TPP enzyme family
A5955_RS10380	COG2814	Major facilitator Superfamily
A5955_RS10385	COG0641	radical SAM
A5955_RS10395	COG2149	membrane
A5955_RS10405	COG3119	arylsulfatase activity
A5955_RS10410	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A5955_RS10415	COG2207	Transcriptional regulator
A5955_RS10430	COG2188	Transcriptional regulator
A5955_RS10450	COG5645	(Lipo)protein
A5955_RS10455	COG0823	Involved in the tonB-independent uptake of proteins
A5955_RS10460	COG0644	oxidoreductase
A5955_RS10470	COG0561	phosphatase activity
A5955_RS10475	COG3753	Protein conserved in bacteria
A5955_RS10485	COG0187	DNA topoisomerase II activity
A5955_RS10495	COG0592	DNA-directed DNA polymerase activity
A5955_RS10545	COG0814	amino acid
A5955_RS10560	COG2091	lysine biosynthetic process via aminoadipic acid
A5955_RS10565	COG0431	NADPH-dependent FMN reductase
A5955_RS10570	COG2252	PERMEase
A5955_RS10575	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A5955_RS10615	COG0704	Plays a role in the regulation of phosphate uptake
A5955_RS10620	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A5955_RS10625	COG0581	inorganic phosphate transmembrane transporter activity
A5955_RS10630	COG0573	inorganic phosphate transmembrane transporter activity
A5955_RS10635	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A5955_RS10645	COG3539	Fimbrial protein
A5955_RS10740	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A5955_RS10790	COG3312	ion transport
A5955_RS10805	COG0716	FMN binding
A5955_RS10810	COG1522	sequence-specific DNA binding
A5955_RS10830	COG3158	transport of potassium into the cell
A5955_RS10840	COG1129	ABC transporter
A5955_RS10845	COG1172	Belongs to the binding-protein-dependent transport system permease family
A5955_RS10850	COG1879	ABC-type sugar transport system periplasmic component
A5955_RS10855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A5955_RS10860	COG1609	Transcriptional regulator
A5955_RS10865	COG0477	Major facilitator Superfamily
A5955_RS10870	COG2186	Transcriptional regulator
A5955_RS10910	COG3085	chromosome segregation
A5955_RS10915	COG0606	chelatase, subunit chli
A5955_RS10930	COG3978	acetolactate synthase activity
A5955_RS10935	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A5955_RS10945	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A5955_RS10950	COG0583	DNA-binding transcription factor activity
A5955_RS10960	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A5955_RS10965	COG3692	DNA binding
A5955_RS10970	COG0210	DNA helicase
A5955_RS10985	COG3118	belongs to the thioredoxin family
A5955_RS10995	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
A5955_RS11005	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A5955_RS11010	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
A5955_RS11015	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
A5955_RS11020	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
A5955_RS11025	COG1088	dTDP-glucose 4,6-dehydratase activity
A5955_RS11030	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
A5955_RS11035	COG0456	acetyltransferase
A5955_RS11040	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A5955_RS11045	COG2244	polysaccharide biosynthetic process
A5955_RS11065	COG1113	amino acid transport
A5955_RS11090	COG0641	radical SAM
A5955_RS11100	COG3119	arylsulfatase activity
A5955_RS11105	COG3071	HemY protein
A5955_RS11110	COG2959	enzyme of heme biosynthesis
A5955_RS11115	COG1587	Uroporphyrinogen-III synthase
A5955_RS11125	COG3072	Adenylate cyclase
A5955_RS11135	COG5567	small periplasmic lipoprotein
A5955_RS11145	COG3159	Protein conserved in bacteria
A5955_RS11155	COG1011	Hydrolase
A5955_RS11160	COG0210	DNA helicase
A5955_RS11165	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
A5955_RS11170	COG3698	Phosphodiester glycosidase
A5955_RS11180	COG0598	Magnesium transport protein CorA
A5955_RS11205	COG2962	Rard protein
A5955_RS11210	COG2050	protein possibly involved in aromatic compounds catabolism
A5955_RS11215	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
A5955_RS11220	COG0514	ATP-dependent DNA helicase (RecQ)
A5955_RS11225	COG1280	lysine exporter protein (LysE YggA)
A5955_RS11230	COG1280	lysine exporter protein (LysE YggA)
A5955_RS11235	COG2267	carboxylic ester hydrolase activity
A5955_RS11240	COG0561	phosphatase activity
A5955_RS11245	COG0697	spore germination
A5955_RS11250	COG0583	DNA-binding transcription factor activity
A5955_RS11260	COG0412	Dienelactone hydrolase
A5955_RS11265	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
A5955_RS11270	COG1322	Protein conserved in bacteria
A5955_RS11280	COG3165	ubiquinone biosynthetic process from chorismate
A5955_RS11290	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A5955_RS11295	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A5955_RS11300	COG0805	protein transport
A5955_RS11305	COG0084	hydrolase, TatD family'
A5955_RS11310	COG0250	Participates in transcription elongation, termination and antitermination
A5955_RS11315	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
A5955_RS11320	COG0543	2 iron, 2 sulfur cluster binding
A5955_RS11325	COG0183	Belongs to the thiolase family
A5955_RS11340	COG1739	Uncharacterized protein family UPF0029
A5955_RS11345	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A5955_RS11350	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
A5955_RS11380	COG1763	Mo-molybdopterin cofactor biosynthetic process
A5955_RS11385	COG0746	molybdenum cofactor guanylyltransferase activity
A5955_RS11390	COG3084	Protein conserved in bacteria
A5955_RS11395	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A5955_RS11400	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A5955_RS11405	COG5339	Protein conserved in bacteria
A5955_RS11410	COG0204	Acyl-transferase
A5955_RS11425	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A5955_RS11425	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A5955_RS11435	COG3078	GTPase activator activity
A5955_RS11440	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A5955_RS11450	COG2204	response regulator
A5955_RS11455	COG3852	Histidine kinase
A5955_RS11460	COG0174	glutamine synthetase
A5955_RS11470	COG1217	gtp-binding protein TYPA
A5955_RS11475	COG2188	Transcriptional regulator
A5955_RS11480	COG1082	Xylose isomerase domain protein TIM barrel
A5955_RS11485	COG2271	Major facilitator Superfamily
A5955_RS11490	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
A5955_RS11495	COG2211	Major facilitator Superfamily
A5955_RS11500	COG2211	Major facilitator Superfamily
A5955_RS11505	COG1501	Belongs to the glycosyl hydrolase 31 family
A5955_RS11515	COG2017	converts alpha-aldose to the beta-anomer
A5955_RS11520	COG2942	2-epimerase
A5955_RS11525	COG3684	Belongs to the aldolase LacD family
A5955_RS11530	COG2084	Dehydrogenase
A5955_RS11535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A5955_RS11540	COG1349	DNA-binding transcription factor activity
A5955_RS11545	COG1011	Hydrolase
A5955_RS11560	COG0456	acetyltransferase
A5955_RS11580	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
A5955_RS11585	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
A5955_RS11600	COG2864	formate dehydrogenase
A5955_RS11605	COG0437	4 iron, 4 sulfur cluster binding
A5955_RS11610	COG3383	formate dehydrogenase (NAD+) activity
A5955_RS11610	COG0243	molybdopterin cofactor binding
A5955_RS11615	COG3383	formate dehydrogenase (NAD+) activity
A5955_RS11615	COG0243	molybdopterin cofactor binding
A5955_RS11630	COG3711	transcriptional antiterminator
A5955_RS11630	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A5955_RS11635	COG1363	Peptidase, m42
A5955_RS11640	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A5955_RS11640	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A5955_RS11645	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A5955_RS11685	COG4977	sequence-specific DNA binding
A5955_RS11685	COG1917	Cupin 2, conserved barrel domain protein
A5955_RS11695	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A5955_RS11710	COG2258	MOSC domain
A5955_RS11715	COG2205	protein histidine kinase activity
A5955_RS11720	COG0745	RESPONSE REGULATOR receiver
A5955_RS11725	COG3678	ATP-independent chaperone mediated protein folding
A5955_RS11745	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
A5955_RS11765	COG3152	Membrane
A5955_RS11770	COG3691	Protein conserved in bacteria
A5955_RS11775	COG0589	response to stress
A5955_RS11785	COG1494	fructose-1,6-bisphosphatase
A5955_RS11795	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A5955_RS11820	COG1575	Belongs to the MenA family. Type 1 subfamily
A5955_RS11835	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
A5955_RS11840	COG1609	Transcriptional regulator
A5955_RS11845	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A5955_RS11855	COG3209	COG3209 Rhs family protein
A5955_RS11885	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
A5955_RS11895	COG0626	cystathionine gamma-synthase activity
A5955_RS11900	COG0527	aspartate kinase activity
A5955_RS11900	COG0460	homoserine dehydrogenase
A5955_RS11910	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
A5955_RS11920	COG0697	spore germination
A5955_RS11925	COG3738	Protein conserved in bacteria
A5955_RS11935	COG0371	Dehydrogenase
A5955_RS11940	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A5955_RS11945	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A5955_RS11945	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A5955_RS11945	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A5955_RS11950	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A5955_RS11955	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A5955_RS11960	COG1882	Formate acetyltransferase
A5955_RS11965	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A5955_RS11970	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A5955_RS11975	COG2207	Transcriptional regulator
A5955_RS11980	COG2194	sulfuric ester hydrolase activity
A5955_RS11995	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
A5955_RS12010	COG0583	DNA-binding transcription factor activity
A5955_RS12020	COG1473	amidohydrolase
A5955_RS12025	COG0477	Major facilitator Superfamily
A5955_RS12040	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A5955_RS12045	COG4206	TonB-dependent receptor
A5955_RS12050	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
A5955_RS12075	COG0812	UDP-N-acetylmuramate dehydrogenase activity
A5955_RS12080	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
A5955_RS12080	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
A5955_RS12120	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A5955_RS12125	COG0250	Participates in transcription elongation, termination and antitermination
A5955_RS12165	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
A5955_RS12170	COG2022	thiamine diphosphate biosynthetic process
A5955_RS12175	COG2104	thiamine diphosphate biosynthetic process
A5955_RS12180	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A5955_RS12215	COG3068	Protein conserved in bacteria
A5955_RS12230	COG3678	ATP-independent chaperone mediated protein folding
A5955_RS12235	COG4191	Histidine kinase
A5955_RS12240	COG2204	response regulator
A5955_RS12245	COG0151	Belongs to the GarS family
A5955_RS12275	COG0456	acetyltransferase
A5955_RS12285	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
A5955_RS12290	COG2224	Isocitrate lyase
A5955_RS12310	COG1414	Transcriptional regulator
A5955_RS12315	COG1410	methionine synthase
A5955_RS12315	COG0646	methionine synthase
A5955_RS12320	COG1283	sodium-dependent phosphate transmembrane transporter activity
A5955_RS12370	COG1187	pseudouridine synthase activity
A5955_RS12380	COG0527	aspartate kinase activity
A5955_RS12405	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A5955_RS12425	COG2814	Major facilitator Superfamily
A5955_RS12425	COG0477	Major facilitator Superfamily
A5955_RS12430	COG3833	ABC-type maltose transport systems, permease component
A5955_RS12435	COG1175	transmembrane transport
A5955_RS12440	COG2182	Extracellular solute-binding protein
A5955_RS12450	COG3842	ATPase activity
A5955_RS12465	COG1357	PFAM Pentapeptide repeats (8 copies)
A5955_RS12485	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
A5955_RS12495	COG0534	Mate efflux family protein
A5955_RS12500	COG3237	CsbD-like
A5955_RS12505	COG0735	belongs to the Fur family
A5955_RS12515	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A5955_RS12525	COG0604	alcohol dehydrogenase
A5955_RS12530	COG0305	Participates in initiation and elongation during chromosome replication
A5955_RS12535	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A5955_RS12540	COG1448	Aminotransferase
A5955_RS12550	COG3700	Belongs to the class B bacterial acid phosphatase family
A5955_RS12555	COG0432	Pfam Uncharacterised protein family UPF0047
A5955_RS12560	COG2315	Protein conserved in bacteria
A5955_RS12565	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A5955_RS12570	COG0629	single-stranded DNA binding
A5955_RS12580	COG4943	cyclic-guanylate-specific phosphodiesterase activity
A5955_RS12585	COG2207	Transcriptional regulator
A5955_RS12590	COG0789	Transcriptional regulator
A5955_RS12595	COG2252	PERMEase
A5955_RS12600	COG0025	NhaP-type Na H and K H
A5955_RS12605	COG1357	PFAM Pentapeptide repeats (8 copies)
A5955_RS12615	COG3162	membrane
A5955_RS12620	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A5955_RS12630	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
A5955_RS12635	COG0437	4 iron, 4 sulfur cluster binding
A5955_RS12640	COG3301	Polysulphide reductase, NrfD
A5955_RS12645	COG1138	Cytochrome C-type biogenesis protein
A5955_RS12650	COG3088	subunit of a heme lyase
A5955_RS12655	COG4235	cytochrome complex assembly
A5955_RS12660	COG1301	dicarboxylic acid transport
A5955_RS12665	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
A5955_RS12670	COG3383	formate dehydrogenase (NAD+) activity
A5955_RS12675	COG3383	formate dehydrogenase (NAD+) activity
A5955_RS12680	COG1538	Outer membrane efflux protein
A5955_RS12685	COG1289	transmembrane transporter activity
A5955_RS12700	COG2015	COG2015, Alkyl sulfatase and related hydrolases
A5955_RS12710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A5955_RS12730	COG1172	Belongs to the binding-protein-dependent transport system permease family
A5955_RS12735	COG1129	ABC transporter
A5955_RS12750	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
A5955_RS12755	COG0456	acetyltransferase
A5955_RS12760	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
A5955_RS12765	COG3454	Phosphonate metabolism
A5955_RS12770	COG4778	phosphonate C-P lyase system protein PhnL
A5955_RS12775	COG4107	phosphonate C-P lyase system protein PhnK
A5955_RS12780	COG3627	carbon phosphorus lyase activity
A5955_RS12785	COG3626	phosphonate metabolism
A5955_RS12790	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
A5955_RS12795	COG3624	Phosphonate C-P lyase system protein PhnG
A5955_RS12800	COG2188	Transcriptional regulator
A5955_RS12805	COG3639	organic phosphonate transmembrane transporter activity
A5955_RS12810	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
A5955_RS12815	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
A5955_RS12820	COG2764	glyoxalase bleomycin resistance protein dioxygenase
A5955_RS12825	COG2824	Alkylphosphonate utilization operon protein PhnA
A5955_RS12830	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
A5955_RS12840	COG0477	Major facilitator Superfamily
A5955_RS12850	COG0642	Histidine kinase
A5955_RS12855	COG0745	RESPONSE REGULATOR receiver
A5955_RS12860	COG2194	sulfuric ester hydrolase activity
A5955_RS12865	COG0531	amino acid
A5955_RS12870	COG2207	Transcriptional regulator
A5955_RS12875	COG1982	Orn Lys Arg decarboxylase major
A5955_RS12880	COG2169	Transcriptional regulator
A5955_RS12890	COG1486	melibiose metabolic process
A5955_RS12895	COG2211	Major facilitator Superfamily
A5955_RS12900	COG3647	Membrane
A5955_RS12905	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
A5955_RS12905	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
A5955_RS12910	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
A5955_RS12920	COG4565	transcriptional regulatory protein
A5955_RS12925	COG3290	protein histidine kinase activity
A5955_RS12930	COG3592	Divergent 4Fe-4S mono-cluster
A5955_RS12935	COG2388	GCN5-related N-acetyl-transferase
A5955_RS12950	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
A5955_RS12955	COG3104	oligopeptide transport
A5955_RS12960	COG1982	Orn Lys Arg decarboxylase major
A5955_RS12965	COG0531	amino acid
A5955_RS12970	COG3710	Transcriptional regulator
A5955_RS13010	COG2003	Belongs to the UPF0758 family
A5955_RS13030	COG3468	outer membrane autotransporter barrel domain protein
A5955_RS13115	COG2433	Pfam Transposase IS66
A5955_RS13120	COG3436	PFAM IS66 Orf2 family protein
A5955_RS13135	COG3335	DDE superfamily endonuclease
A5955_RS13165	COG3328	transposase activity
A5955_RS13230	COG2801	Transposase and inactivated derivatives
A5955_RS13255	COG4372	Transposase
A5955_RS13270	COG2963	transposase activity
A5955_RS13275	COG2826	transposase and inactivated derivatives, IS30 family
A5955_RS13285	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
A5955_RS13285	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A5955_RS13290	COG0582	viral genome integration into host DNA
A5955_RS13300	COG1309	transcriptional regulator
A5955_RS13305	COG4232	protein-disulfide reductase activity
A5955_RS13315	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
A5955_RS13320	COG1027	Aspartate ammonia-lyase
A5955_RS13325	COG3030	protein affecting phage T7 exclusion by the F plasmid
A5955_RS13330	COG0531	amino acid
A5955_RS13355	COG1509	lysine 2,3-aminomutase activity
A5955_RS13365	COG5510	response to toxic substance
A5955_RS13370	COG5510	response to toxic substance
A5955_RS13375	COG2076	Multidrug Resistance protein
A5955_RS13380	COG3040	lipid binding
A5955_RS13385	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A5955_RS13400	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A5955_RS13405	COG1053	succinate dehydrogenase
A5955_RS13415	COG0531	amino acid
A5955_RS13420	COG3264	Mechanosensitive ion channel
A5955_RS13420	COG1511	domain protein
A5955_RS13435	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
A5955_RS13460	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
A5955_RS13460	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
A5955_RS13465	COG0802	atpase or kinase
A5955_RS13470	COG0860	N-Acetylmuramoyl-L-alanine amidase
A5955_RS13490	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A5955_RS13495	COG0330	HflC and HflK could
A5955_RS13500	COG0330	HflC and HflK could
A5955_RS13505	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
A5955_RS13520	COG0557	exoribonuclease II activity
A5955_RS13525	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A5955_RS13530	COG3789	protein conserved in bacteria
A5955_RS13535	COG1842	Phage shock protein A
A5955_RS13545	COG3766	membrane
A5955_RS13550	COG5463	Belongs to the UPF0441 family
A5955_RS13555	COG0754	glutathionylspermidine amidase activity
A5955_RS13560	COG1960	acyl-CoA dehydrogenase activity
A5955_RS13570	COG3650	response to hydrogen peroxide
A5955_RS13575	COG1073	alpha beta
A5955_RS13590	COG3037	sugar-specific permease SgaT UlaA
A5955_RS13595	COG3414	Phosphotransferase system galactitol-specific IIB component
A5955_RS13600	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A5955_RS13635	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
A5955_RS13650	COG1309	transcriptional regulator
A5955_RS13660	COG0675	Transposase, IS605 OrfB family
A5955_RS13665	COG3061	Opacity-associated protein A
A5955_RS13670	COG0545	Peptidyl-prolyl cis-trans isomerase
A5955_RS13675	COG1113	amino acid transport
A5955_RS13685	COG0697	spore germination
A5955_RS13690	COG0702	epimerase
A5955_RS13695	COG1733	regulation of RNA biosynthetic process
A5955_RS13700	COG0737	Belongs to the 5'-nucleotidase family
A5955_RS13705	COG1218	3'(2'),5'-bisphosphate nucleotidase
A5955_RS13715	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
A5955_RS13725	COG1253	flavin adenine dinucleotide binding
A5955_RS13740	COG0729	surface antigen
A5955_RS13745	COG2911	Protein conserved in bacteria
A5955_RS13750	COG2105	PFAM AIG2 family protein
A5955_RS13755	COG2336	PFAM SpoVT AbrB
A5955_RS13760	COG2337	Toxic component of a toxin-antitoxin (TA) module
A5955_RS13765	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
A5955_RS13770	COG1879	ABC-type sugar transport system periplasmic component
A5955_RS13775	COG1129	ABC transporter
A5955_RS13780	COG1172	Belongs to the binding-protein-dependent transport system permease family
A5955_RS13785	COG1172	Belongs to the binding-protein-dependent transport system permease family
A5955_RS13795	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
A5955_RS13805	COG0312	modulator of DNA gyrase
A5955_RS13810	COG3783	Cytochrome b(562)
A5955_RS13815	COG0602	queuosine metabolic process
A5955_RS13820	COG1328	CTP reductase activity
A5955_RS13825	COG0366	Alpha amylase catalytic
A5955_RS13830	COG1263	PTS System
A5955_RS13830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A5955_RS13835	COG1609	Transcriptional regulator
A5955_RS13840	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A5955_RS13845	COG0251	oxidation-reduction process
A5955_RS13870	COG0251	oxidation-reduction process
A5955_RS13875	COG1028	Short-chain dehydrogenase reductase Sdr
A5955_RS13880	COG1309	transcriptional regulator
A5955_RS13885	COG2731	YhcH YjgK YiaL family protein
A5955_RS13895	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
A5955_RS13900	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
A5955_RS13905	COG0456	acetyltransferase
A5955_RS13910	COG4269	membrane
A5955_RS13920	COG2927	DNA polymerase III (CHI subunit)
A5955_RS13930	COG0795	lipopolysaccharide-transporting ATPase activity
A5955_RS13935	COG0795	lipopolysaccharide-transporting ATPase activity
A5955_RS13940	COG0433	COG0433 Predicted ATPase
A5955_RS13945	COG1064	alcohol dehydrogenase
A5955_RS13955	COG0582	viral genome integration into host DNA
A5955_RS14000	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A5955_RS14010	COG1111	helicase
A5955_RS14010	COG1205	dead DEAH box helicase
A5955_RS14015	COG0210	DNA helicase
A5955_RS14045	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
A5955_RS14050	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
A5955_RS14065	COG0582	viral genome integration into host DNA
A5955_RS14070	COG4974	Belongs to the 'phage' integrase family
A5955_RS14080	COG3539	Fimbrial protein
A5955_RS14085	COG3539	Fimbrial protein
A5955_RS14090	COG3121	Chaperone
A5955_RS14095	COG3188	usher protein
A5955_RS14100	COG3539	Fimbrial protein
A5955_RS14105	COG3539	Fimbrial protein
A5955_RS14110	COG3539	Fimbrial protein
A5955_RS14115	COG2610	gluconate transmembrane transporter activity
A5955_RS14130	COG0246	Mannitol dehydrogenase
A5955_RS14140	COG2186	Transcriptional regulator
A5955_RS14170	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A5955_RS14175	COG0700	Nucleoside recognition
A5955_RS14180	COG3366	ferrous iron transmembrane transporter activity
A5955_RS14190	COG1388	LysM domain
A5955_RS14190	COG1470	cell adhesion involved in biofilm formation
A5955_RS14195	COG0477	Major facilitator Superfamily
A5955_RS14200	COG3204	pilus organization
A5955_RS14215	COG1924	4 iron, 4 sulfur cluster binding
A5955_RS14220	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
A5955_RS14225	COG2733	membrane
A5955_RS14230	COG2814	Major facilitator Superfamily
A5955_RS14240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A5955_RS14245	COG5457	Domain of unknown function (DUF1127)
A5955_RS14265	COG0732	type I restriction modification DNA specificity domain
A5955_RS14290	COG0523	cobalamin synthesis protein
A5955_RS14295	COG2879	small protein
A5955_RS14300	COG1966	Carbon starvation protein
A5955_RS14315	COG0840	transmembrane signaling receptor activity
A5955_RS14320	COG2271	Major facilitator Superfamily
A5955_RS14325	COG1802	Transcriptional regulator
A5955_RS14330	COG1063	alcohol dehydrogenase
A5955_RS14345	COG1484	DNA-dependent DNA replication
A5955_RS14360	COG2966	Psort location CytoplasmicMembrane, score
A5955_RS14365	COG2197	response regulator
A5955_RS14370	COG2197	response regulator
A5955_RS14375	COG4114	ferric iron reductase
A5955_RS14410	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
A5955_RS14415	COG0456	acetyltransferase
A5955_RS14420	COG1011	Hydrolase
A5955_RS14430	COG2823	Periplasmic or secreted lipoprotein
A5955_RS14440	COG4667	esterase of the alpha-beta hydrolase superfamily
A5955_RS14445	COG0084	hydrolase, TatD family'
A5955_RS14450	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A5955_RS14455	COG1328	CTP reductase activity
A5955_RS14490	COG0095	Lipoate-protein ligase
A5955_RS14490	COG3726	membrane protein affecting hemolysin expression
A5955_RS14495	COG3726	membrane protein affecting hemolysin expression
A5955_RS14500	COG0560	Phosphoserine phosphatase
A5955_RS14505	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
A5955_RS14510	COG3172	ATPase kinase involved in NAD metabolism
A5955_RS14510	COG1056	cytidyltransferase-related domain
A5955_RS14520	COG0488	(ABC) transporter
A5955_RS14525	COG0741	lytic transglycosylase activity
A5955_RS14535	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
A5955_RS14545	COG3708	Transcriptional regulator
A5955_RS14545	COG2207	Transcriptional regulator
A5955_RS14550	COG3045	CreA protein
A5955_RS14555	COG0745	RESPONSE REGULATOR receiver
A5955_RS14560	COG2205	protein histidine kinase activity
A5955_RS14565	COG4452	Inner membrane protein CreD
A5955_RS14570	COG0745	RESPONSE REGULATOR receiver
A5955_RS14580	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
A5955_RS14590	COG0460	homoserine dehydrogenase
A5955_RS14590	COG0527	aspartate kinase activity
A5955_RS14600	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A5955_RS14625	COG1115	amino acid carrier protein
A5955_RS14630	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A5955_RS14635	COG0521	Mo-molybdopterin cofactor biosynthetic process
A5955_RS14640	COG1584	GPR1 FUN34 yaaH family protein
A5955_RS14645	COG4735	regulation of single-species biofilm formation
A5955_RS14675	COG0583	DNA-binding transcription factor activity
A5955_RS14685	COG3188	usher protein
A5955_RS14690	COG3121	Chaperone
A5955_RS14715	COG0196	riboflavin kinase activity
A5955_RS14730	COG1047	Peptidyl-prolyl cis-trans
A5955_RS14760	COG0505	Belongs to the CarA family
A5955_RS14765	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
A5955_RS14820	COG0644	oxidoreductase
A5955_RS14825	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
A5955_RS14830	COG2271	Major facilitator Superfamily
A5955_RS14845	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
A5955_RS14880	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A5955_RS14885	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
A5955_RS14890	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
A5955_RS14895	COG1357	PFAM Pentapeptide repeats (8 copies)
A5955_RS14900	COG0564	pseudouridine synthase activity
A5955_RS14910	COG0417	DNA replication proofreading
A5955_RS14915	COG0235	Class ii aldolase
A5955_RS14930	COG4977	sequence-specific DNA binding
A5955_RS14935	COG0586	Pfam SNARE associated Golgi protein
A5955_RS14940	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
A5955_RS14945	COG1178	ABC-type Fe3 transport system permease component
A5955_RS14950	COG4143	(ABC) transporter
A5955_RS14960	COG4533	DNA binding
A5955_RS14980	COG0473	3-isopropylmalate dehydrogenase activity
A5955_RS14995	COG0583	DNA-binding transcription factor activity
A5955_RS15000	COG0028	Belongs to the TPP enzyme family
A5955_RS15005	COG0440	acetolactate synthase activity
A5955_RS15015	COG1609	Transcriptional regulator
A5955_RS15030	COG3116	cell division
A5955_RS15035	COG0768	penicillin binding
A5955_RS15040	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
A5955_RS15045	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A5955_RS15055	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
A5955_RS15060	COG0772	Belongs to the SEDS family
A5955_RS15075	COG1181	Belongs to the D-alanine--D-alanine ligase family
A5955_RS15080	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
A5955_RS15085	COG0849	cell division
A5955_RS15090	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A5955_RS15110	COG0494	nUDIX hydrolase
A5955_RS15130	COG0237	dephospho-CoA kinase activity
A5955_RS15140	COG1459	type II secretion system
A5955_RS15150	COG4969	Belongs to the N-Me-Phe pilin family
A5955_RS15160	COG0157	Belongs to the NadC ModD family
A5955_RS15165	COG3023	N-Acetylmuramoyl-L-alanine amidase
A5955_RS15170	COG3725	Membrane protein required for beta-lactamase induction
A5955_RS15180	COG2186	Transcriptional regulator
A5955_RS15185	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
A5955_RS15190	COG0508	dehydrogenase complex catalyzes the overall conversion of
A5955_RS15195	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A5955_RS15200	COG3064	Membrane
A5955_RS15205	COG1049	propionate catabolic process, 2-methylcitrate cycle
A5955_RS15230	COG2132	Multicopper oxidase
A5955_RS15235	COG4993	Dehydrogenase
A5955_RS15240	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
A5955_RS15245	COG0288	reversible hydration of carbon dioxide
A5955_RS15250	COG1131	(ABC) transporter
A5955_RS15255	COG0842	Transport permease protein
A5955_RS15260	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
A5955_RS15265	COG0726	polysaccharide deacetylase
A5955_RS15275	COG5464	transposase or invertase
A5955_RS15300	COG3539	Fimbrial protein
A5955_RS15305	COG3539	Fimbrial protein
A5955_RS15310	COG3188	usher protein
A5955_RS15315	COG3121	Chaperone
A5955_RS15325	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A5955_RS15330	COG0617	tRNA 3'-terminal CCA addition
A5955_RS15335	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A5955_RS15340	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A5955_RS15350	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
A5955_RS15355	COG1643	Atp-dependent helicase
A5955_RS15365	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A5955_RS15375	COG1120	ATPase activity
A5955_RS15380	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A5955_RS15385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A5955_RS15405	COG2860	membrane
A5955_RS15410	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A5955_RS15425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A5955_RS15430	COG3835	regulator
A5955_RS15450	COG0024	Methionine aminopeptidase
A5955_RS15475	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
A5955_RS15480	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A5955_RS15485	COG0575	Belongs to the CDS family
A5955_RS15490	COG0750	zinc metalloprotease
A5955_RS15500	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
A5955_RS15505	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A5955_RS15530	COG0587	DNA-directed DNA polymerase activity
A5955_RS15540	COG1982	Orn Lys Arg decarboxylase major
A5955_RS15545	COG0346	lactoylglutathione lyase activity
A5955_RS15550	COG0037	tRNA processing
A5955_RS15555	COG4568	rho-dependent transcription termination
A5955_RS15565	COG4681	YaeQ
A5955_RS15570	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
A5955_RS15575	COG3015	lipoprotein NlpE involved in copper resistance
A5955_RS15580	COG0791	NLP P60 protein
A5955_RS15590	COG1720	tRNA m6t6A37 methyltransferase activity
A5955_RS15600	COG1464	Belongs to the NlpA lipoprotein family
A5955_RS15605	COG2011	ABC-type metal ion transport system permease component
A5955_RS15610	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A5955_RS15615	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
A5955_RS15650	COG0656	L-ascorbic acid biosynthetic process
A5955_RS15655	COG0583	DNA-binding transcription factor activity
A5955_RS15665	COG2226	methyltransferase
A5955_RS15670	COG0741	lytic transglycosylase activity
A5955_RS15670	COG1388	LysM domain
A5955_RS15680	COG2226	methyltransferase
A5955_RS15690	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A5955_RS15825	COG3209	COG3209 Rhs family protein
A5955_RS15830	COG0666	response to abiotic stimulus
A5955_RS15835	COG3209	COG3209 Rhs family protein
A5955_RS15855	COG5433	transposase activity
A5955_RS15860	COG3209	COG3209 Rhs family protein
A5955_RS15875	COG5433	transposase activity
A5955_RS15880	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A5955_RS15890	COG1960	acyl-CoA dehydrogenase activity
A5955_RS15900	COG0121	glutamine amidotransferase
A5955_RS15905	COG3034	peptidoglycan biosynthetic process
A5955_RS15910	COG3041	Addiction module toxin RelE StbE family
A5955_RS15915	COG3077	Addiction module antitoxin, RelB DinJ family
A5955_RS15920	COG0791	NLP P60 protein
A5955_RS15940	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A5955_RS15945	COG2161	toxin-antitoxin pair type II binding
A5955_RS15955	COG0454	-acetyltransferase
A5955_RS15960	COG1690	Belongs to the RtcB family
A5955_RS15965	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
A5955_RS15970	COG2195	Cleaves the N-terminal amino acid of tripeptides
A5955_RS15990	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
A5955_RS16010	COG0582	viral genome integration into host DNA
A5955_RS16185	COG3772	lysozyme
A5955_RS16275	COG1196	nuclear chromosome segregation
A5955_RS16310	COG5301	cellulose 1,4-beta-cellobiosidase activity
A5955_RS16345	COG0582	viral genome integration into host DNA
A5955_RS16365	COG0582	viral genome integration into host DNA
A5955_RS16450	COG0583	DNA-binding transcription factor activity
A5955_RS16455	COG4221	oxidoreductase activity
A5955_RS16465	COG0583	DNA-binding transcription factor activity
A5955_RS16485	COG1529	Aldehyde oxidase and xanthine dehydrogenase
A5955_RS16490	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
A5955_RS16495	COG2080	2 iron, 2 sulfur cluster binding
A5955_RS16500	COG3477	response to acidic pH
A5955_RS16505	COG0727	PFAM Uncharacterised protein family (UPF0153)
A5955_RS16520	COG3188	usher protein
A5955_RS16555	COG1902	pentaerythritol trinitrate reductase activity
A5955_RS16560	COG1073	alpha beta
A5955_RS16565	COG0583	DNA-binding transcription factor activity
A5955_RS16575	COG0656	L-ascorbic acid biosynthetic process
A5955_RS16580	COG1388	LysM domain
A5955_RS16585	COG3708	Transcriptional regulator
A5955_RS16585	COG2207	Transcriptional regulator
A5955_RS16590	COG0656	L-ascorbic acid biosynthetic process
A5955_RS16595	COG3059	membrane
A5955_RS16605	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A5955_RS16610	COG2207	Transcriptional regulator
A5955_RS16615	COG0247	lactate metabolic process
A5955_RS16620	COG1139	Iron-sulfur cluster binding protein
A5955_RS16625	COG1556	Lactate utilization protein
A5955_RS16640	COG3468	outer membrane autotransporter barrel domain protein
A5955_RS16650	COG2200	EAL domain
A5955_RS16650	COG2771	luxR family
A5955_RS16680	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A5955_RS16690	COG2771	luxR family
A5955_RS16690	COG2200	EAL domain
A5955_RS16705	COG0666	response to abiotic stimulus
A5955_RS16715	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
A5955_RS16720	COG1304	FMN binding
A5955_RS16735	COG0549	Belongs to the carbamate kinase family
A5955_RS16740	COG0402	S-adenosylhomocysteine deaminase activity
A5955_RS16750	COG1879	ABC-type sugar transport system periplasmic component
A5955_RS16755	COG1129	ABC transporter
A5955_RS16760	COG1172	Belongs to the binding-protein-dependent transport system permease family
A5955_RS16770	COG1064	alcohol dehydrogenase
A5955_RS16785	COG1280	lysine exporter protein (LysE YggA)
A5955_RS16795	COG3829	transcription factor binding
A5955_RS16800	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
A5955_RS16805	COG0372	Belongs to the citrate synthase family
A5955_RS16810	COG2079	MmgE PrpD family protein
A5955_RS16815	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A5955_RS16820	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
A5955_RS16825	COG0402	S-adenosylhomocysteine deaminase activity
A5955_RS16830	COG0583	DNA-binding transcription factor activity
A5955_RS16835	COG0288	reversible hydration of carbon dioxide
A5955_RS16845	COG2807	transmembrane transport
A5955_RS16850	COG0110	maltose O-acetyltransferase activity
A5955_RS16855	COG2223	nitrite transmembrane transporter activity
A5955_RS16860	COG3250	beta-galactosidase activity
A5955_RS16865	COG1609	Transcriptional regulator
A5955_RS16875	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A5955_RS16880	COG1414	Transcriptional regulator
A5955_RS16895	COG0596	Alpha beta hydrolase
A5955_RS16910	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A5955_RS16915	COG2814	Major facilitator Superfamily
A5955_RS16920	COG3122	Protein conserved in bacteria
A5955_RS16925	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
A5955_RS16940	COG3842	ATPase activity
A5955_RS16950	COG1840	ABC-type Fe3 transport system, periplasmic component
A5955_RS16955	COG2271	Major facilitator Superfamily
A5955_RS16970	COG4521	taurine ABC transporter
A5955_RS16975	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
A5955_RS16980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A5955_RS16985	COG2175	clavaminate synthase activity
A5955_RS16990	COG0113	porphobilinogen synthase activity
A5955_RS16995	COG3468	outer membrane autotransporter barrel domain protein
A5955_RS17000	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A5955_RS17005	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A5955_RS17015	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
A5955_RS17040	COG1181	Belongs to the D-alanine--D-alanine ligase family
A5955_RS17055	COG1785	Belongs to the alkaline phosphatase family
A5955_RS17065	COG3706	GGDEF domain
A5955_RS17070	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A5955_RS17095	COG4126	flavin adenine dinucleotide binding
A5955_RS17120	COG1940	carbohydrate kinase activity
A5955_RS17125	COG2814	Major facilitator Superfamily
A5955_RS17130	COG0419	ATPase involved in DNA repair
A5955_RS17135	COG0420	3'-5' exonuclease activity
A5955_RS17140	COG0745	RESPONSE REGULATOR receiver
A5955_RS17145	COG5002	protein histidine kinase activity
A5955_RS17150	COG1114	Component of the transport system for branched-chain amino acids
A5955_RS17155	COG1113	amino acid transport
A5955_RS17160	COG0366	Alpha amylase catalytic
A5955_RS17185	COG1862	Preprotein translocase
A5955_RS17190	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A5955_RS17195	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A5955_RS17200	COG3609	addiction module antidote protein, CC2985 family
A5955_RS17210	COG1403	HNH endonuclease
A5955_RS17220	COG3248	Nucleoside-binding outer membrane protein
A5955_RS17225	COG4238	major outer membrane lipoprotein
A5955_RS17235	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A5955_RS17235	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A5955_RS17250	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
A5955_RS17255	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
A5955_RS17265	COG0667	Aldo Keto reductase
A5955_RS17275	COG0142	geranyltranstransferase activity
A5955_RS17290	COG0693	protein deglycase activity
A5955_RS17295	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A5955_RS17305	COG2814	Major facilitator Superfamily
A5955_RS17315	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
A5955_RS17320	COG1845	cytochrome c oxidase, subunit III
A5955_RS17325	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A5955_RS17330	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
A5955_RS17335	COG2223	nitrite transmembrane transporter activity
A5955_RS17340	COG3056	Lipoprotein
A5955_RS17345	COG0271	Belongs to the BolA IbaG family
A5955_RS17370	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
A5955_RS17375	COG0776	regulation of translation
A5955_RS17380	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A5955_RS17385	COG1555	photosystem II stabilization
A5955_RS17390	COG0824	Thioesterase
A5955_RS17400	COG4533	DNA binding
A5955_RS17410	COG1522	sequence-specific DNA binding
A5955_RS17415	COG1132	(ABC) transporter
A5955_RS17420	COG1132	(ABC) transporter
A5955_RS17425	COG0347	Belongs to the P(II) protein family
A5955_RS17430	COG0004	ammonium transporteR
A5955_RS17435	COG1946	Acyl-CoA thioesterase
A5955_RS17440	COG3126	Type III secretion system lipoprotein chaperone (YscW)
A5955_RS17445	COG3695	enzyme binding
A5955_RS17455	COG5507	3-demethylubiquinone-9 3-methyltransferase
A5955_RS17460	COG4943	cyclic-guanylate-specific phosphodiesterase activity
A5955_RS17470	COG0110	maltose O-acetyltransferase activity
A5955_RS17485	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A5955_RS17490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A5955_RS17495	COG1309	transcriptional regulator
A5955_RS17500	COG1196	nuclear chromosome segregation
A5955_RS17500	COG3264	Mechanosensitive ion channel
A5955_RS17510	COG3923	Primosomal replication protein n
A5955_RS17515	COG2832	Protein of unknown function (DUF454)
A5955_RS17525	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A5955_RS17560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A5955_RS17565	COG4651	solute:proton antiporter activity
A5955_RS17565	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A5955_RS17570	COG2223	nitrite transmembrane transporter activity
A5955_RS17575	COG0737	Belongs to the 5'-nucleotidase family
A5955_RS17580	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A5955_RS17585	COG3735	TraB family
A5955_RS17590	COG3093	addiction module antidote protein HigA
A5955_RS17595	COG2217	Heavy metal translocating P-type atpase
A5955_RS17600	COG2066	Belongs to the glutaminase family
A5955_RS17605	COG0531	amino acid
A5955_RS17630	COG0789	Transcriptional regulator
A5955_RS17655	COG1585	Membrane protein implicated in regulation of membrane protease activity
A5955_RS17660	COG0330	HflC and HflK could
A5955_RS17665	COG4619	ABC transporter
A5955_RS17670	COG0390	transport system, permease component
A5955_RS17675	COG3118	belongs to the thioredoxin family
A5955_RS17680	COG0300	oxidoreductase activity
A5955_RS17685	COG2755	lipolytic protein G-D-S-L family
A5955_RS17690	COG4181	ATPase activity
A5955_RS17695	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
A5955_RS17705	COG3209	COG3209 Rhs family protein
A5955_RS17715	COG2801	Transposase and inactivated derivatives
A5955_RS17725	COG0583	DNA-binding transcription factor activity
A5955_RS17735	COG1414	Transcriptional regulator
A5955_RS17740	COG3960	tartronate-semialdehyde synthase activity
A5955_RS17745	COG3622	Belongs to the hyi family
A5955_RS17750	COG2084	Dehydrogenase
A5955_RS17755	COG1953	Uracil, thiamine, allantoin
A5955_RS17765	COG2233	PERMEase
A5955_RS17770	COG1929	Belongs to the glycerate kinase type-1 family
A5955_RS17775	COG3257	ureidoglycine aminohydrolase activity
A5955_RS17780	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A5955_RS17785	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
A5955_RS17790	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
A5955_RS17795	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
A5955_RS17805	COG0549	Belongs to the carbamate kinase family
A5955_RS17810	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
A5955_RS17815	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A5955_RS17825	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A5955_RS17835	COG1988	membrane-bound metal-dependent
A5955_RS17840	COG2501	S4 domain
A5955_RS17850	COG3539	Fimbrial protein
A5955_RS17855	COG3121	Chaperone
A5955_RS17860	COG3188	usher protein
A5955_RS17865	COG3539	Fimbrial protein
A5955_RS17870	COG3539	Fimbrial protein
A5955_RS17875	COG2197	response regulator
A5955_RS17885	COG0582	viral genome integration into host DNA
A5955_RS17975	COG2076	Multidrug Resistance protein
A5955_RS17985	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
A5955_RS17990	COG1881	PFAM PEBP family protein
A5955_RS17995	COG2207	Transcriptional regulator
A5955_RS18040	COG3772	lysozyme
A5955_RS18060	COG4220	transposase activity
A5955_RS18080	COG1030	water channel activity
A5955_RS18130	COG1196	nuclear chromosome segregation
A5955_RS18165	COG5301	cellulose 1,4-beta-cellobiosidase activity
A5955_RS18170	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
A5955_RS18175	COG0500	methyltransferase
A5955_RS18190	COG4571	Outer membrane protease
A5955_RS18200	COG0456	acetyltransferase
A5955_RS18210	COG2207	Transcriptional regulator
A5955_RS18220	COG4783	chaperone-mediated protein folding
A5955_RS18225	COG1215	transferase activity, transferring glycosyl groups
A5955_RS18230	COG5433	transposase activity
A5955_RS18240	COG4104	PAAR repeat-containing protein
A5955_RS18240	COG3209	COG3209 Rhs family protein
A5955_RS18250	COG4104	PAAR repeat-containing protein
A5955_RS18250	COG3209	COG3209 Rhs family protein
A5955_RS18265	COG5002	protein histidine kinase activity
A5955_RS18270	COG0745	RESPONSE REGULATOR receiver
A5955_RS18275	COG1538	Outer membrane efflux protein
A5955_RS18280	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A5955_RS18285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A5955_RS18290	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A5955_RS18295	COG1113	amino acid transport
A5955_RS18300	COG0668	transmembrane transport
A5955_RS18305	COG0778	Nitroreductase
A5955_RS18310	COG2315	Protein conserved in bacteria
A5955_RS18340	COG2977	Belongs to the P-Pant transferase superfamily
A5955_RS18350	COG4771	TonB-dependent receptor
A5955_RS18355	COG2382	esterase
A5955_RS18360	COG3251	PFAM MbtH domain protein
A5955_RS18365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A5955_RS18365	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
A5955_RS18370	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
A5955_RS18375	COG1120	ATPase activity
A5955_RS18380	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A5955_RS18385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A5955_RS18395	COG4592	Periplasmic binding protein
A5955_RS18400	COG1169	isochorismate synthase
A5955_RS18405	COG1021	2,3-dihydroxybenzoate-AMP ligase
A5955_RS18410	COG1535	isochorismatase
A5955_RS18410	COG3433	isochorismatase activity
A5955_RS18415	COG1028	Short-chain dehydrogenase reductase Sdr
A5955_RS18420	COG2050	protein possibly involved in aromatic compounds catabolism
A5955_RS18425	COG1966	Carbon starvation protein
A5955_RS18430	COG2879	small protein
A5955_RS18435	COG0371	Dehydrogenase
A5955_RS18440	COG0436	Aminotransferase
A5955_RS18445	COG1475	DNA binding
A5955_RS18455	COG0583	DNA-binding transcription factor activity
A5955_RS18460	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A5955_RS18465	COG0450	alkyl hydroperoxide reductase
A5955_RS18470	COG3634	alkyl hydroperoxide reductase activity
A5955_RS18475	COG0589	response to stress
A5955_RS18480	COG1063	alcohol dehydrogenase
A5955_RS18490	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A5955_RS18495	COG3719	Belongs to the RNase T2 family
A5955_RS18500	COG0471	metal ion transport
A5955_RS18505	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
A5955_RS18515	COG3051	citrate lyase alpha subunit
A5955_RS18520	COG2301	Belongs to the HpcH HpaI aldolase family
A5955_RS18530	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
A5955_RS18535	COG3290	protein histidine kinase activity
A5955_RS18545	COG3069	C4-dicarboxylate transmembrane transporter activity
A5955_RS18565	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A5955_RS18570	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A5955_RS18580	COG0583	DNA-binding transcription factor activity
A5955_RS18600	COG1686	Belongs to the peptidase S11 family
A5955_RS18605	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
A5955_RS18610	COG0772	Belongs to the SEDS family
A5955_RS18615	COG0768	penicillin binding
A5955_RS18625	COG0799	negative regulation of ribosome biogenesis
A5955_RS18630	COG0406	alpha-ribazole phosphatase activity
A5955_RS18640	COG1466	dna polymerase III delta subunit
A5955_RS18655	COG2888	peptidyl-tyrosine sulfation
A5955_RS18660	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
A5955_RS18670	COG2214	Heat shock protein DnaJ domain protein
A5955_RS18675	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
A5955_RS18690	COG0443	Heat shock 70 kDa protein
A5955_RS18700	COG1126	abc transporter atp-binding protein
A5955_RS18705	COG0765	amino acid transport
A5955_RS18710	COG0765	amino acid transport
A5955_RS18715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A5955_RS18720	COG0815	Transfers the fatty acyl group on membrane lipoproteins
A5955_RS18725	COG4535	Mg2 and Co2 transporter CorC
A5955_RS18735	COG1702	phosphate starvation-inducible protein PhoH
A5955_RS18745	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A5955_RS18785	COG0367	asparagine synthase
A5955_RS18790	COG0647	UMP catabolic process
A5955_RS18795	COG1940	carbohydrate kinase activity
A5955_RS18795	COG1846	Transcriptional regulator
A5955_RS18800	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A5955_RS18810	COG2190	(PTS) system
A5955_RS18810	COG1263	PTS System
A5955_RS18810	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A5955_RS18830	COG0735	belongs to the Fur family
A5955_RS18845	COG0716	FMN binding
A5955_RS18855	COG0596	Alpha beta hydrolase
A5955_RS18860	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
A5955_RS18865	COG0033	Phosphoglucomutase
A5955_RS18870	COG0531	amino acid
A5955_RS18875	COG1982	Orn Lys Arg decarboxylase major
A5955_RS18885	COG0745	RESPONSE REGULATOR receiver
A5955_RS18890	COG2205	protein histidine kinase activity
A5955_RS18920	COG3209	COG3209 Rhs family protein
A5955_RS18935	COG5433	transposase activity
A5955_RS18940	COG3272	Protein of unknown function (DUF1722)
A5955_RS18945	COG0415	Belongs to the DNA photolyase family
A5955_RS18950	COG3104	oligopeptide transport
A5955_RS18955	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A5955_RS18960	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A5955_RS18965	COG1984	allophanate hydrolase subunit 2
A5955_RS18975	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
A5955_RS18980	COG3180	Ammonia monooxygenase
A5955_RS18985	COG3539	Fimbrial protein
A5955_RS18990	COG3121	Chaperone
A5955_RS18995	COG3188	usher protein
A5955_RS19000	COG3539	Fimbrial protein
A5955_RS19005	COG0372	Belongs to the citrate synthase family
A5955_RS19015	COG2009	succinate dehydrogenase
A5955_RS19020	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
A5955_RS19025	COG1053	succinate dehydrogenase
A5955_RS19030	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A5955_RS19040	COG0567	Dehydrogenase, E1 component
A5955_RS19045	COG0508	dehydrogenase complex catalyzes the overall conversion of
A5955_RS19055	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
A5955_RS19060	COG0583	DNA-binding transcription factor activity
A5955_RS19065	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
A5955_RS19070	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
A5955_RS19070	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
A5955_RS19075	COG1301	dicarboxylic acid transport
A5955_RS19090	COG3799	methylaspartate ammonia-lyase activity
A5955_RS19095	COG4865	methylaspartate mutase activity
A5955_RS19105	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A5955_RS19125	COG1271	oxidase subunit
A5955_RS19130	COG1294	oxidase, subunit
A5955_RS19135	COG4890	Cyd operon protein YbgT
A5955_RS19140	COG3790	cyd operon protein YbgE
A5955_RS19145	COG0824	Thioesterase
A5955_RS19150	COG0811	peptide transport
A5955_RS19155	COG0848	biopolymer transport protein
A5955_RS19160	COG3064	Membrane
A5955_RS19170	COG2885	chlorophyll binding
A5955_RS19175	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
A5955_RS19220	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
A5955_RS19225	COG3201	nicotinamide mononucleotide transporter
A5955_RS19230	COG1230	cation diffusion facilitator family transporter
A5955_RS19240	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A5955_RS19250	COG2017	converts alpha-aldose to the beta-anomer
A5955_RS19260	COG1085	galactose-1-phosphate uridylyltransferase
A5955_RS19265	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A5955_RS19270	COG1119	ATPase activity
A5955_RS19275	COG2005	Transcriptional regulator
A5955_RS19275	COG3585	molybdate ion transport
A5955_RS19285	COG0725	ABC transporter, periplasmic molybdate-binding protein
A5955_RS19290	COG4149	molybdate abc transporter
A5955_RS19300	COG0561	phosphatase activity
A5955_RS19310	COG0583	DNA-binding transcription factor activity
A5955_RS19315	COG2828	Protein conserved in bacteria
A5955_RS19320	COG0471	metal ion transport
A5955_RS19325	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
A5955_RS19330	COG4677	pectinesterase activity
A5955_RS19335	COG0582	viral genome integration into host DNA
A5955_RS19500	COG3772	lysozyme
A5955_RS19625	COG5301	cellulose 1,4-beta-cellobiosidase activity
A5955_RS19660	COG1881	PFAM PEBP family protein
A5955_RS19665	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A5955_RS19680	COG2226	methyltransferase
A5955_RS19685	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
A5955_RS19695	COG0391	Required for morphogenesis under gluconeogenic growth conditions
A5955_RS19705	COG0521	Mo-molybdopterin cofactor biosynthetic process
A5955_RS19715	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
A5955_RS19720	COG0314	molybdopterin synthase activity
A5955_RS19725	COG0670	Belongs to the BI1 family
A5955_RS19730	COG0670	Belongs to the BI1 family
A5955_RS19735	COG0392	lysyltransferase activity
A5955_RS19740	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A5955_RS19745	COG3568	Endonuclease Exonuclease Phosphatase
A5955_RS19755	COG0842	Transport permease protein
A5955_RS19760	COG0842	Transport permease protein
A5955_RS19765	COG1131	(ABC) transporter
A5955_RS19775	COG1309	transcriptional regulator
A5955_RS19780	COG0513	Belongs to the DEAD box helicase family
A5955_RS19795	COG1199	ATP-dependent helicase activity
A5955_RS19800	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A5955_RS19805	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
A5955_RS19815	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A5955_RS19825	COG4774	siderophore transport
A5955_RS19840	COG0668	transmembrane transport
A5955_RS19850	COG1126	abc transporter atp-binding protein
A5955_RS19855	COG0765	amino acid transport
A5955_RS19860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A5955_RS19875	COG5006	permease, DMT superfamily
A5955_RS19880	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
A5955_RS19885	COG2194	sulfuric ester hydrolase activity
A5955_RS19895	COG1321	iron dependent repressor
A5955_RS19900	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A5955_RS19905	COG1376	ErfK ybiS ycfS ynhG family protein
A5955_RS19910	COG0488	(ABC) transporter
A5955_RS19920	COG0561	phosphatase activity
A5955_RS19925	COG1882	Formate acetyltransferase
A5955_RS19930	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A5955_RS19935	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A5955_RS19940	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A5955_RS19945	COG0303	'Molybdopterin
A5955_RS19950	COG1446	asparaginase
A5955_RS19955	COG4172	Belongs to the ABC transporter superfamily
A5955_RS19960	COG0747	negative chemotaxis
A5955_RS19975	COG2200	EAL domain
A5955_RS19980	COG2199	diguanylate cyclase activity
A5955_RS20005	COG2133	pyrroloquinoline quinone binding
A5955_RS20010	COG0625	glutathione transferase activity
A5955_RS20015	COG1686	Belongs to the peptidase S11 family
A5955_RS20020	COG1349	DNA-binding transcription factor activity
A5955_RS20025	COG0671	phosphoesterase, PA-phosphatase related
A5955_RS20030	COG2814	Major facilitator Superfamily
A5955_RS20040	COG0561	phosphatase activity
A5955_RS20045	COG0738	Major facilitator superfamily
A5955_RS20050	COG3226	Transcriptional regulator
A5955_RS20065	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
A5955_RS20075	COG0778	Nitroreductase
A5955_RS20095	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
A5955_RS20100	COG3842	ATPase activity
A5955_RS20105	COG1176	ABC-type spermidine putrescine transport system, permease component I
A5955_RS20110	COG1177	transmembrane transport
A5955_RS20140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A5955_RS20145	COG4160	amino acid transport
A5955_RS20150	COG4215	(ABC) transporter
A5955_RS20155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A5955_RS20160	COG1126	abc transporter atp-binding protein
A5955_RS20195	COG3023	N-Acetylmuramoyl-L-alanine amidase
A5955_RS20200	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A5955_RS20205	COG0702	epimerase
A5955_RS20210	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
A5955_RS20215	COG0028	Belongs to the TPP enzyme family
A5955_RS20220	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A5955_RS20230	COG2431	L-lysine efflux transmembrane transporter activity
A5955_RS20235	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A5955_RS20245	COG3593	DNA synthesis involved in DNA repair
A5955_RS20250	COG2990	Protein conserved in bacteria
A5955_RS20255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A5955_RS20260	COG1136	(ABC) transporter
A5955_RS20260	COG0577	efflux transmembrane transporter activity
A5955_RS20265	COG1278	Cold shock
A5955_RS20275	COG0542	response to heat
A5955_RS20295	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
A5955_RS20300	COG4988	ABC transporter
A5955_RS20305	COG0492	ferredoxin-NADP+ reductase activity
A5955_RS20310	COG1522	sequence-specific DNA binding
A5955_RS20325	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A5955_RS20335	COG0243	molybdopterin cofactor binding
A5955_RS20340	COG0437	4 iron, 4 sulfur cluster binding
A5955_RS20345	COG3302	dmso reductase anchor subunit
A5955_RS20350	COG1335	isochorismatase
A5955_RS20360	COG0531	amino acid
A5955_RS20365	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A5955_RS20370	COG1882	Formate acetyltransferase
A5955_RS20375	COG2116	formate transmembrane transporter activity
A5955_RS20380	COG1944	ATP diphosphatase activity
A5955_RS20385	COG2323	membrane
A5955_RS20400	COG0501	Belongs to the peptidase M48B family
A5955_RS20410	COG0539	negative regulation of cytoplasmic translation
A5955_RS20420	COG2333	competence protein COMEC
A5955_RS20420	COG0658	competence protein
A5955_RS20425	COG1132	(ABC) transporter
A5955_RS20435	COG3214	Protein conserved in bacteria
A5955_RS20450	COG3173	Aminoglycoside phosphotransferase
A5955_RS20455	COG1434	Gram-negative-bacterium-type cell wall biogenesis
A5955_RS20460	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A5955_RS20470	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
A5955_RS20480	COG2989	Protein conserved in bacteria
A5955_RS20485	COG3108	Peptidase M15
A5955_RS20490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A5955_RS20495	COG1448	Aminotransferase
A5955_RS20510	COG0017	Asparaginyl-tRNA synthetase
A5955_RS20520	COG0308	aminopeptidase N
A5955_RS20525	COG1116	anion transmembrane transporter activity
A5955_RS20530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A5955_RS20540	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A5955_RS20545	COG0431	NADPH-dependent FMN reductase
A5955_RS20550	COG3539	Fimbrial protein
A5955_RS20555	COG3121	Chaperone
A5955_RS20565	COG3539	Fimbrial protein
A5955_RS20570	COG3539	Fimbrial protein
A5955_RS20575	COG3539	Fimbrial protein
A5955_RS20580	COG3121	Chaperone
A5955_RS20595	COG0633	Ferredoxin
A5955_RS20595	COG3217	Mosc domain protein beta barrel domain protein
A5955_RS20605	COG0488	(ABC) transporter
A5955_RS20610	COG2995	paraquat-inducible protein a
A5955_RS20615	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
A5955_RS20615	COG3008	intermembrane lipid transfer
A5955_RS20620	COG3009	Protein conserved in bacteria
A5955_RS20625	COG3130	regulation of translation
A5955_RS20635	COG1067	ATP-dependent peptidase activity
A5955_RS20645	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
A5955_RS20645	COG2885	chlorophyll binding
A5955_RS20660	COG3070	regulator of competence-specific genes
A5955_RS20665	COG1289	transmembrane transporter activity
A5955_RS20670	COG3304	Inner membrane component domain
A5955_RS20675	COG0210	DNA helicase
A5955_RS20695	COG1832	CoA-binding protein
A5955_RS20710	COG1254	Belongs to the acylphosphatase family
A5955_RS20715	COG2920	part of a sulfur-relay system
A5955_RS20720	COG0670	Belongs to the BI1 family
A5955_RS20730	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
A5955_RS20735	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
A5955_RS20740	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
A5955_RS20745	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
A5955_RS20750	COG1999	signal sequence binding
A5955_RS20755	COG1773	rubredoxin
A5955_RS20760	COG1271	oxidase subunit
A5955_RS20765	COG1294	oxidase, subunit
A5955_RS20780	COG0489	protein tyrosine kinase activity
A5955_RS20780	COG3206	protein involved in exopolysaccharide biosynthesis
A5955_RS20785	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A5955_RS20790	COG1596	polysaccharide export
A5955_RS20795	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A5955_RS20815	COG1278	Cold shock
A5955_RS20820	COG1278	Cold shock
A5955_RS20835	COG0348	domain, Protein
A5955_RS20840	COG2198	Histidine kinase
A5955_RS20840	COG2205	protein histidine kinase activity
A5955_RS20840	COG0784	Response regulator, receiver
A5955_RS20845	COG1879	ABC-type sugar transport system periplasmic component
A5955_RS20850	COG0745	RESPONSE REGULATOR receiver
A5955_RS20855	COG3005	denitrification pathway
A5955_RS20860	COG0243	molybdopterin cofactor binding
A5955_RS20905	COG3729	General stress protein
A5955_RS20910	COG2233	PERMEase
A5955_RS20945	COG1309	transcriptional regulator
A5955_RS20950	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
A5955_RS20950	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
A5955_RS20950	COG0506	proline dehydrogenase activity
A5955_RS20960	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A5955_RS20980	COG2822	iron ion transport
A5955_RS20985	COG2837	iron assimilation
A5955_RS20995	COG1702	phosphate starvation-inducible protein PhoH
A5955_RS21000	COG3658	cytochrome
A5955_RS21005	COG1215	transferase activity, transferring glycosyl groups
A5955_RS21015	COG0457	Tetratricopeptide repeat
A5955_RS21025	COG2200	EAL domain
A5955_RS21035	COG3710	Transcriptional regulator
A5955_RS21040	COG1028	Short-chain dehydrogenase reductase Sdr
A5955_RS21045	COG3121	Chaperone
A5955_RS21055	COG3188	usher protein
A5955_RS21065	COG3539	Fimbrial protein
A5955_RS21075	COG3210	domain, Protein
A5955_RS21080	COG2831	hemolysin activation secretion protein
A5955_RS21085	COG0736	holo-[acyl-carrier-protein] synthase activity
A5955_RS21095	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
A5955_RS21105	COG0404	The glycine cleavage system catalyzes the degradation of glycine
A5955_RS21110	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A5955_RS21175	COG3381	protein complex oligomerization
A5955_RS21185	COG1462	curli production assembly transport component CsgG
A5955_RS21200	COG2197	response regulator
A5955_RS21230	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
A5955_RS21235	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A5955_RS21255	COG2943	transferase activity, transferring hexosyl groups
A5955_RS21260	COG5645	(Lipo)protein
A5955_RS21280	COG1560	Kdo2-lipid A biosynthetic process
A5955_RS21290	COG2353	YceI-like domain
A5955_RS21295	COG3038	cytochrome b561
A5955_RS21330	COG2999	glutathione oxidoreductase activity
A5955_RS21340	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A5955_RS21350	COG0673	inositol 2-dehydrogenase activity
A5955_RS21355	COG0728	peptidoglycan biosynthetic process
A5955_RS21360	COG3418	PFAM FlgN family protein
A5955_RS21365	COG2747	anti-sigma28 factor FlgM
A5955_RS21370	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
A5955_RS21375	COG1815	bacterial-type flagellum-dependent cell motility
A5955_RS21380	COG1558	bacterial-type flagellum-dependent cell motility
A5955_RS21385	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
A5955_RS21390	COG1749	Flagellar hook protein flgE
A5955_RS21395	COG4787	bacterial-type flagellum-dependent cell motility
A5955_RS21400	COG4786	Flagellar basal body rod
A5955_RS21415	COG3951	Flagellar rod assembly protein muramidase FlgJ
A5955_RS21415	COG1705	Flagellar rod assembly protein muramidase FlgJ
A5955_RS21420	COG1256	bacterial-type flagellum assembly
A5955_RS21425	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A5955_RS21430	COG1530	ribonuclease E activity
A5955_RS21440	COG0564	pseudouridine synthase activity
A5955_RS21445	COG0424	maF-like protein
A5955_RS21450	COG1399	metal-binding, possibly nucleic acid-binding protein
A5955_RS21470	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A5955_RS21475	COG1028	Short-chain dehydrogenase reductase Sdr
A5955_RS21485	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A5955_RS21490	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A5955_RS21495	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A5955_RS21505	COG0470	DNA polymerase III
A5955_RS21510	COG0084	hydrolase, TatD family'
A5955_RS21515	COG1263	PTS System
A5955_RS21515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A5955_RS21520	COG4773	Receptor
A5955_RS21525	COG0537	adenosine 5'-monophosphoramidase activity
A5955_RS21530	COG5633	Lipoprotein
A5955_RS21535	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
A5955_RS21540	COG0510	thiamine kinase activity
A5955_RS21555	COG1252	NADH dehydrogenase
A5955_RS21560	COG3134	Outer membrane lipoprotein
A5955_RS21565	COG1309	transcriptional regulator
A5955_RS21575	COG1388	LysM domain
A5955_RS21575	COG1376	ErfK ybiS ycfS ynhG family protein
A5955_RS21580	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A5955_RS21585	COG4763	Acyl-transferase
A5955_RS21590	COG4591	ABC-type transport system involved in lipoprotein release permease component
A5955_RS21595	COG1136	(ABC) transporter
A5955_RS21600	COG4591	ABC-type transport system involved in lipoprotein release permease component
A5955_RS21610	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
A5955_RS21615	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
A5955_RS21620	COG1177	transmembrane transport
A5955_RS21630	COG3842	ATPase activity
A5955_RS21645	COG2850	peptidyl-arginine hydroxylation
A5955_RS21735	COG4220	transposase activity
A5955_RS21745	COG2205	protein histidine kinase activity
A5955_RS21750	COG0745	RESPONSE REGULATOR receiver
A5955_RS21755	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A5955_RS21765	COG0482	sulfurtransferase activity
A5955_RS21775	COG1187	pseudouridine synthase activity
A5955_RS21780	COG0538	isocitrate dehydrogenase activity
A5955_RS21795	COG5562	phage envelope protein
A5955_RS21800	COG0789	Transcriptional regulator
A5955_RS21830	COG2200	EAL domain
A5955_RS21875	COG3468	outer membrane autotransporter barrel domain protein
A5955_RS21885	COG2894	cell division
A5955_RS21915	COG0179	Fumarylacetoacetate (FAA) hydrolase
A5955_RS21930	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
A5955_RS21935	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A5955_RS21940	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
A5955_RS21955	COG2719	SpoVR family
A5955_RS21965	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A5955_RS21980	COG1619	proteins homologs of microcin C7 resistance protein MccF
A5955_RS21990	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
A5955_RS22005	COG0157	Belongs to the NadC ModD family
A5955_RS22010	COG0500	methyltransferase
A5955_RS22015	COG1120	ATPase activity
A5955_RS22020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A5955_RS22025	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A5955_RS22035	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A5955_RS22035	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A5955_RS22035	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
A5955_RS22040	COG1461	Dihydroxyacetone kinase
A5955_RS22045	COG2376	Dihydroxyacetone kinase
A5955_RS22050	COG3284	Transcriptional regulator
A5955_RS22055	COG3468	outer membrane autotransporter barrel domain protein
A5955_RS22065	COG0012	GTP binding
A5955_RS22080	COG0659	secondary active sulfate transmembrane transporter activity
A5955_RS22085	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A5955_RS22115	COG3094	Invasion gene expression up-regulator, SirB
A5955_RS22120	COG2912	Transglutaminase-like superfamily
A5955_RS22140	COG0387	Pfam Sodium calcium exchanger
A5955_RS22145	COG4572	Cation transport regulator
A5955_RS22150	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
A5955_RS22155	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
A5955_RS22160	COG4932	domain protein
A5955_RS22165	COG2197	response regulator
A5955_RS22170	COG3850	Histidine kinase
A5955_RS22180	COG2223	nitrite transmembrane transporter activity
A5955_RS22185	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
A5955_RS22190	COG1140	nitrate reductase beta subunit
A5955_RS22195	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
A5955_RS22200	COG2181	nitrate reductase activity
A5955_RS22225	COG0788	formyltetrahydrofolate deformylase activity
A5955_RS22235	COG1752	Esterase of the alpha-beta hydrolase superfamily
A5955_RS22240	COG0745	RESPONSE REGULATOR receiver
A5955_RS22245	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A5955_RS22255	COG1435	thymidine kinase activity
A5955_RS22260	COG1012	belongs to the aldehyde dehydrogenase family
A5955_RS22260	COG1454	alcohol dehydrogenase
A5955_RS22265	COG2095	MarC family integral membrane protein
A5955_RS22270	COG4166	transmembrane transport
A5955_RS22275	COG0601	transmembrane transport
A5955_RS22280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A5955_RS22285	COG0444	Belongs to the ABC transporter superfamily
A5955_RS22290	COG4608	Belongs to the ABC transporter superfamily
A5955_RS22310	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A5955_RS22315	COG2350	Protein conserved in bacteria
A5955_RS22320	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
A5955_RS22325	COG1607	acyl-coa hydrolase
A5955_RS22340	COG3047	cAMP biosynthetic process
A5955_RS22345	COG0582	viral genome integration into host DNA
A5955_RS22355	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A5955_RS22395	COG1396	sequence-specific DNA binding
A5955_RS22420	COG1846	Transcriptional regulator
A5955_RS22445	COG1403	HNH endonuclease
A5955_RS22450	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
A5955_RS22500	COG3772	lysozyme
A5955_RS22580	COG2826	transposase and inactivated derivatives, IS30 family
A5955_RS22585	COG2963	transposase activity
A5955_RS22650	COG5301	cellulose 1,4-beta-cellobiosidase activity
A5955_RS22670	COG0582	viral genome integration into host DNA
A5955_RS22685	COG3328	transposase activity
A5955_RS22690	COG3328	transposase activity
A5955_RS22700	COG0582	viral genome integration into host DNA
A5955_RS22710	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A5955_RS22760	COG1846	Transcriptional regulator
A5955_RS22765	COG1484	DNA-dependent DNA replication
A5955_RS22770	COG1846	Transcriptional regulator
A5955_RS22775	COG1846	Transcriptional regulator
A5955_RS22815	COG1403	HNH endonuclease
A5955_RS22820	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
A5955_RS22825	COG0484	heat shock protein binding
A5955_RS22860	COG3772	lysozyme
A5955_RS22900	COG0740	serine-type endopeptidase activity
A5955_RS22975	COG5301	cellulose 1,4-beta-cellobiosidase activity
A5955_RS22985	COG3677	Transposase
A5955_RS23005	COG3685	Protein conserved in bacteria
A5955_RS23010	COG3685	Protein conserved in bacteria
A5955_RS23015	COG3729	General stress protein
A5955_RS23030	COG0134	indole-3-glycerol-phosphate synthase activity
A5955_RS23030	COG0135	phosphoribosylanthranilate isomerase activity
A5955_RS23035	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A5955_RS23035	COG0512	Glutamine amidotransferase of anthranilate synthase
A5955_RS23040	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A5955_RS23045	COG0613	PHP domain protein
A5955_RS23050	COG0009	L-threonylcarbamoyladenylate synthase
A5955_RS23055	COG4907	membrane protein (DUF2207)
A5955_RS23060	COG1187	pseudouridine synthase activity
A5955_RS23065	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
A5955_RS23070	COG1028	Short-chain dehydrogenase reductase Sdr
A5955_RS23080	COG0616	signal peptide processing
A5955_RS23095	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A5955_RS23100	COG0583	DNA-binding transcription factor activity
A5955_RS23120	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
A5955_RS23130	COG0671	phosphoesterase, PA-phosphatase related
A5955_RS23135	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
A5955_RS23140	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
A5955_RS23150	COG0023	Translation Initiation Factor
A5955_RS23160	COG1349	DNA-binding transcription factor activity
A5955_RS23170	COG5001	Diguanylate cyclase
A5955_RS23180	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A5955_RS23180	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A5955_RS23185	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
A5955_RS23195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A5955_RS23200	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A5955_RS23210	COG2814	Major facilitator Superfamily
A5955_RS23215	COG4172	Belongs to the ABC transporter superfamily
A5955_RS23220	COG4172	Belongs to the ABC transporter superfamily
A5955_RS23225	COG4171	peptide transport system, permease
A5955_RS23230	COG4168	peptide transport system, permease
A5955_RS23235	COG4166	transmembrane transport
A5955_RS23250	COG0531	amino acid
A5955_RS23255	COG0174	glutamine synthetase
A5955_RS23260	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
A5955_RS23265	COG1917	Cupin 2, conserved barrel domain protein
A5955_RS23265	COG1396	sequence-specific DNA binding
A5955_RS23270	COG1012	belongs to the aldehyde dehydrogenase family
A5955_RS23275	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A5955_RS23280	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A5955_RS23285	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
A5955_RS23290	COG1842	Phage shock protein A
A5955_RS23300	COG1983	PspC domain protein
A5955_RS23310	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A5955_RS23315	COG0366	Alpha amylase catalytic
A5955_RS23320	COG0366	Alpha amylase catalytic
A5955_RS23325	COG1653	transport
A5955_RS23330	COG1175	transmembrane transport
A5955_RS23335	COG0395	ABC-type sugar transport system, permease component
A5955_RS23340	COG1063	alcohol dehydrogenase
A5955_RS23345	COG1082	Xylose isomerase domain protein TIM barrel
A5955_RS23350	COG0673	inositol 2-dehydrogenase activity
A5955_RS23355	COG1554	hydrolase, family 65, central catalytic
A5955_RS23360	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A5955_RS23365	COG3842	ATPase activity
A5955_RS23375	COG1609	Transcriptional regulator
A5955_RS23380	COG3106	COG3106 Predicted ATPase
A5955_RS23390	COG3283	Transcriptional regulator of aromatic amino acids metabolism
A5955_RS23395	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
A5955_RS23400	COG4948	Mandelate Racemase Muconate Lactonizing
A5955_RS23405	COG2866	Carboxypeptidase
A5955_RS23410	COG0702	epimerase
A5955_RS23420	COG1073	alpha beta
A5955_RS23425	COG1073	alpha beta
A5955_RS23430	COG0583	DNA-binding transcription factor activity
A5955_RS23435	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
A5955_RS23440	COG4166	transmembrane transport
A5955_RS23445	COG0668	transmembrane transport
A5955_RS23450	COG3182	Iron-regulated membrane protein
A5955_RS23455	COG0589	response to stress
A5955_RS23460	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A5955_RS23465	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A5955_RS23470	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
A5955_RS23480	COG1473	amidohydrolase
A5955_RS23485	COG1473	amidohydrolase
A5955_RS23490	COG0583	DNA-binding transcription factor activity
A5955_RS23500	COG2840	Smr protein MutS2
A5955_RS23505	COG3706	GGDEF domain
A5955_RS23520	COG0513	Belongs to the DEAD box helicase family
A5955_RS23530	COG0589	response to stress
A5955_RS23535	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
A5955_RS23540	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A5955_RS23540	COG1013	pyruvate-flavodoxin oxidoreductase activity
A5955_RS23540	COG0674	pyruvate-flavodoxin oxidoreductase activity
A5955_RS23540	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A5955_RS23545	COG3042	response to heat
A5955_RS23550	COG3187	Heat shock protein
A5955_RS23555	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A5955_RS23560	COG2911	Protein conserved in bacteria
A5955_RS23570	COG3784	Protein of unknown function (DUF1318)
A5955_RS23585	COG0667	Aldo Keto reductase
A5955_RS23595	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A5955_RS23600	COG4589	Belongs to the CDS family
A5955_RS23605	COG2267	carboxylic ester hydrolase activity
A5955_RS23610	COG0671	phosphoesterase, PA-phosphatase related
A5955_RS23610	COG2453	phosphatase
A5955_RS23615	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
A5955_RS23620	COG1643	Atp-dependent helicase
A5955_RS23645	COG1434	Gram-negative-bacterium-type cell wall biogenesis
A5955_RS23650	COG1012	belongs to the aldehyde dehydrogenase family
A5955_RS23655	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A5955_RS23660	COG3038	cytochrome b561
A5955_RS23675	COG0840	transmembrane signaling receptor activity
A5955_RS23680	COG0583	DNA-binding transcription factor activity
A5955_RS23685	COG5383	Protein conserved in bacteria
A5955_RS23700	COG2841	Protein conserved in bacteria
A5955_RS23705	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A5955_RS23710	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
A5955_RS23715	COG1275	C4-dicarboxylate transporter malic acid transport protein
A5955_RS23720	COG0500	methyltransferase
A5955_RS23730	COG3135	benzoate transporter
A5955_RS23735	COG1396	sequence-specific DNA binding
A5955_RS23740	COG0826	peptidase U32
A5955_RS23750	COG1724	mRNA binding
A5955_RS23755	COG1598	PFAM Uncharacterised protein family UPF0150
A5955_RS23760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A5955_RS23765	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
A5955_RS23770	COG3842	ATPase activity
A5955_RS23775	COG1176	ABC-type spermidine putrescine transport system, permease component I
A5955_RS23780	COG1177	transmembrane transport
A5955_RS23805	COG3238	Protein conserved in bacteria
A5955_RS23810	COG1247	-acetyltransferase
A5955_RS23815	COG2130	NADP-dependent
A5955_RS23820	COG1802	Transcriptional regulator
A5955_RS23825	COG4772	TonB-dependent receptor
A5955_RS23830	COG3391	amine dehydrogenase activity
A5955_RS23835	COG1113	amino acid transport
A5955_RS23840	COG0625	glutathione transferase activity
A5955_RS23870	COG5433	transposase activity
A5955_RS23885	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A5955_RS23890	COG2162	N-hydroxyarylamine O-acetyltransferase activity
A5955_RS23895	COG0384	phenazine biosynthesis protein PhzF
A5955_RS23900	COG2181	nitrate reductase activity
A5955_RS23905	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
A5955_RS23910	COG1140	nitrate reductase beta subunit
A5955_RS23915	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
A5955_RS23920	COG2223	nitrite transmembrane transporter activity
A5955_RS23925	COG4886	Leucine-rich repeat (LRR) protein
A5955_RS23930	COG4886	Leucine-rich repeat (LRR) protein
A5955_RS23945	COG0697	spore germination
A5955_RS23950	COG0243	molybdopterin cofactor binding
A5955_RS23950	COG3383	formate dehydrogenase (NAD+) activity
A5955_RS23955	COG0243	molybdopterin cofactor binding
A5955_RS23955	COG3383	formate dehydrogenase (NAD+) activity
A5955_RS23960	COG0437	4 iron, 4 sulfur cluster binding
A5955_RS23965	COG2864	formate dehydrogenase
A5955_RS23970	COG3093	addiction module antidote protein HigA
A5955_RS23975	COG1064	alcohol dehydrogenase
A5955_RS23995	COG1764	response to oxidative stress
A5955_RS24000	COG4608	Belongs to the ABC transporter superfamily
A5955_RS24005	COG0444	Belongs to the ABC transporter superfamily
A5955_RS24010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A5955_RS24015	COG0601	transmembrane transport
A5955_RS24020	COG0747	negative chemotaxis
A5955_RS24025	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
A5955_RS24030	COG2200	EAL domain
A5955_RS24030	COG2202	Pas domain
A5955_RS24030	COG2199	diguanylate cyclase activity
A5955_RS24035	COG3706	GGDEF domain
A5955_RS24040	COG1649	PFAM Uncharacterised BCR, COG1649
A5955_RS24045	COG0531	amino acid
A5955_RS24050	COG0076	glutamate decarboxylase activity
A5955_RS24060	COG0612	Peptidase, M16
A5955_RS24065	COG4771	TonB-dependent receptor
A5955_RS24070	COG4178	(ABC) transporter
A5955_RS24075	COG0641	radical SAM
A5955_RS24080	COG3119	arylsulfatase activity
A5955_RS24085	COG2207	Transcriptional regulator
A5955_RS24095	COG0243	molybdopterin cofactor binding
A5955_RS24100	COG3539	Fimbrial protein
A5955_RS24105	COG3539	Fimbrial protein
A5955_RS24110	COG3539	Fimbrial protein
A5955_RS24115	COG3188	usher protein
A5955_RS24125	COG3539	Fimbrial protein
A5955_RS24130	COG4977	sequence-specific DNA binding
A5955_RS24135	COG3550	peptidyl-serine autophosphorylation
A5955_RS24140	COG1396	sequence-specific DNA binding
A5955_RS24150	COG3210	domain, Protein
A5955_RS24150	COG2911	Protein conserved in bacteria
A5955_RS24155	COG1070	Carbohydrate kinase
A5955_RS24165	COG1129	ABC transporter
A5955_RS24170	COG1172	Belongs to the binding-protein-dependent transport system permease family
A5955_RS24175	COG1172	Belongs to the binding-protein-dependent transport system permease family
A5955_RS24200	COG3781	membrane
A5955_RS24215	COG2199	diguanylate cyclase activity
A5955_RS24225	COG2066	Belongs to the glutaminase family
A5955_RS24230	COG1012	belongs to the aldehyde dehydrogenase family
A5955_RS24235	COG0583	DNA-binding transcription factor activity
A5955_RS24250	COG2814	Major facilitator Superfamily
A5955_RS24260	COG1846	Transcriptional regulator
A5955_RS24265	COG4977	sequence-specific DNA binding
A5955_RS24275	COG0697	spore germination
A5955_RS24280	COG2814	Major facilitator Superfamily
A5955_RS24300	COG3706	GGDEF domain
A5955_RS24305	COG3111	PFAM Bacterial OB fold (BOF) protein
A5955_RS24310	COG1546	Belongs to the CinA family
A5955_RS24315	COG0339	signal peptide processing
A5955_RS24320	COG4221	oxidoreductase activity
A5955_RS24325	COG1802	Transcriptional regulator
A5955_RS24335	COG0246	Mannitol dehydrogenase
A5955_RS24340	COG0477	Major facilitator Superfamily
A5955_RS24350	COG3328	transposase activity
A5955_RS24375	COG5301	cellulose 1,4-beta-cellobiosidase activity
A5955_RS24480	COG4220	transposase activity
A5955_RS24505	COG3772	lysozyme
A5955_RS24550	COG0484	heat shock protein binding
A5955_RS24555	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
A5955_RS24560	COG1403	HNH endonuclease
A5955_RS24615	COG1846	Transcriptional regulator
A5955_RS24655	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A5955_RS24665	COG0582	viral genome integration into host DNA
A5955_RS24670	COG1063	alcohol dehydrogenase
A5955_RS24675	COG4948	Mandelate Racemase Muconate Lactonizing
A5955_RS24690	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A5955_RS24705	COG0243	molybdopterin cofactor binding
A5955_RS24710	COG0243	molybdopterin cofactor binding
A5955_RS24715	COG0437	4 iron, 4 sulfur cluster binding
A5955_RS24720	COG3302	dmso reductase anchor subunit
A5955_RS24725	COG3381	protein complex oligomerization
A5955_RS24735	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
A5955_RS24740	COG1940	carbohydrate kinase activity
A5955_RS24745	COG0583	DNA-binding transcription factor activity
A5955_RS24750	COG2814	Major facilitator Superfamily
A5955_RS24765	COG3591	Belongs to the peptidase S1B family
A5955_RS24780	COG0628	permease
A5955_RS24785	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
A5955_RS24790	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
A5955_RS24800	COG0531	amino acid
A5955_RS24810	COG3136	membrane protein required for alginate biosynthesis
A5955_RS24815	COG0745	RESPONSE REGULATOR receiver
A5955_RS24820	COG2205	protein histidine kinase activity
A5955_RS24830	COG0114	fumarate hydratase activity
A5955_RS24835	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
A5955_RS24835	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
A5955_RS24840	COG1482	cell wall glycoprotein biosynthetic process
A5955_RS24845	COG5339	Protein conserved in bacteria
A5955_RS24860	COG3250	beta-galactosidase activity
A5955_RS24865	COG1309	transcriptional regulator
A5955_RS24870	COG1028	Short-chain dehydrogenase reductase Sdr
A5955_RS24875	COG1609	Transcriptional regulator
A5955_RS24880	COG1263	PTS System
A5955_RS24880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A5955_RS24885	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
A5955_RS24895	COG0673	inositol 2-dehydrogenase activity
A5955_RS24935	COG4659	FMN binding
A5955_RS24945	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A5955_RS24955	COG3104	oligopeptide transport
A5955_RS24960	COG0625	glutathione transferase activity
A5955_RS24965	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
A5955_RS24980	COG3895	Periplasmic Protein
A5955_RS24990	COG3133	Outer membrane lipoprotein
A5955_RS25005	COG1566	PFAM secretion protein HlyD family protein
A5955_RS25010	COG1289	transmembrane transporter activity
A5955_RS25015	COG2032	superoxide dismutase activity
A5955_RS25020	COG4989	oxidoreductase activity
A5955_RS25025	COG3313	Fe-S protein
A5955_RS25030	COG1309	transcriptional regulator
A5955_RS25035	COG1902	pentaerythritol trinitrate reductase activity
A5955_RS25040	COG0346	lactoylglutathione lyase activity
A5955_RS25050	COG1201	RNA secondary structure unwinding
A5955_RS25055	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
A5955_RS25060	COG0791	NLP P60 protein
A5955_RS25065	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A5955_RS25070	COG2814	Major facilitator Superfamily
A5955_RS25085	COG0583	DNA-binding transcription factor activity
A5955_RS25090	COG2814	Major facilitator Superfamily
A5955_RS25095	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A5955_RS25100	COG0307	riboflavin synthase, alpha
A5955_RS25110	COG3468	outer membrane autotransporter barrel domain protein
A5955_RS25130	COG4529	Protein conserved in bacteria
A5955_RS25140	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
A5955_RS25145	COG0437	4 iron, 4 sulfur cluster binding
A5955_RS25155	COG2414	aldehyde ferredoxin oxidoreductase
A5955_RS25160	COG0437	4 iron, 4 sulfur cluster binding
A5955_RS25170	COG0469	pyruvate kinase activity
A5955_RS25175	COG4238	major outer membrane lipoprotein
A5955_RS25180	COG1376	ErfK ybiS ycfS ynhG family protein
A5955_RS25195	COG0719	Fe-S assembly protein
A5955_RS25200	COG0396	ATPase activity
A5955_RS25205	COG0719	Fe-S assembly protein
A5955_RS25210	COG0316	Belongs to the HesB IscA family
A5955_RS25220	COG2050	protein possibly involved in aromatic compounds catabolism
A5955_RS25225	COG0277	FAD linked oxidase domain protein
A5955_RS25225	COG0247	lactate metabolic process
A5955_RS25230	COG0628	permease
A5955_RS25245	COG0738	Major facilitator superfamily
A5955_RS25250	COG2271	Major facilitator Superfamily
A5955_RS25265	COG4670	ketone body catabolic process
A5955_RS25270	COG1960	acyl-CoA dehydrogenase activity
A5955_RS25275	COG2207	Transcriptional regulator
A5955_RS25275	COG1917	Cupin 2, conserved barrel domain protein
A5955_RS25285	COG2086	electron transfer activity
A5955_RS25290	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
A5955_RS25295	COG0644	oxidoreductase
A5955_RS25300	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
A5955_RS25305	COG0318	PFAM AMP-dependent synthetase and ligase
A5955_RS25310	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A5955_RS25310	COG0574	Belongs to the PEP-utilizing enzyme family
A5955_RS25325	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A5955_RS25330	COG4256	Hemin uptake protein
A5955_RS25340	COG2200	EAL domain
A5955_RS25345	COG0791	NLP P60 protein
A5955_RS25355	COG0386	Belongs to the glutathione peroxidase family
A5955_RS25370	COG0072	phenylalanine-tRNA ligase activity
A5955_RS25370	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A5955_RS25415	COG3137	Salt-induced outer membrane protein
A5955_RS25420	COG1105	Belongs to the carbohydrate kinase PfkB family
A5955_RS25430	COG3001	Fructosamine kinase
A5955_RS25440	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A5955_RS25445	COG1988	membrane-bound metal-dependent
A5955_RS25450	COG1823	symporter activity
A5955_RS25465	COG0753	catalase activity
A5955_RS25475	COG1486	melibiose metabolic process
A5955_RS25480	COG2169	Transcriptional regulator
A5955_RS25480	COG1917	Cupin 2, conserved barrel domain protein
A5955_RS25485	COG1447	Phosphotransferase system cellobiose-specific component IIA
A5955_RS25490	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A5955_RS25495	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A5955_RS25500	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A5955_RS25515	COG0322	excinuclease ABC activity
A5955_RS25525	COG3678	ATP-independent chaperone mediated protein folding
A5955_RS25555	COG0708	Exodeoxyribonuclease III
A5955_RS25560	COG0398	Pfam SNARE associated Golgi protein
A5955_RS25570	COG0398	Pfam SNARE associated Golgi protein
A5955_RS25575	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A5955_RS25580	COG4134	Bacterial extracellular solute-binding protein
A5955_RS25585	COG4135	transport system, permease component
A5955_RS25590	COG4136	ATPase activity
A5955_RS25595	COG2897	thiosulfate sulfurtransferase activity
A5955_RS25600	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A5955_RS25605	COG0494	nUDIX hydrolase
A5955_RS25615	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A5955_RS25630	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A5955_RS25635	COG0709	Synthesizes selenophosphate from selenide and ATP
A5955_RS25645	COG0778	Nitroreductase
A5955_RS25655	COG0616	signal peptide processing
A5955_RS25665	COG0252	asparaginase activity
A5955_RS25670	COG1335	isochorismatase
A5955_RS25675	COG2814	Major facilitator Superfamily
A5955_RS25680	COG1349	DNA-binding transcription factor activity
A5955_RS25685	COG0667	Aldo Keto reductase
A5955_RS25690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A5955_RS25695	COG0191	fructose-bisphosphate aldolase activity
A5955_RS25700	COG1063	alcohol dehydrogenase
A5955_RS25705	COG2271	Major facilitator Superfamily
A5955_RS25710	COG1063	alcohol dehydrogenase
A5955_RS25715	COG3139	Protein of unknown function (DUF1315)
A5955_RS25725	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A5955_RS25730	COG0676	glucose-6-phosphate 1-epimerase activity
A5955_RS25740	COG3713	MltA-interacting MipA family protein
A5955_RS25745	COG2766	serine protein kinase
A5955_RS25755	COG2199	diguanylate cyclase activity
A5955_RS25760	COG2199	diguanylate cyclase activity
A5955_RS25765	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A5955_RS25780	COG2207	Transcriptional regulator
A5955_RS25785	COG2807	transmembrane transport
A5955_RS25790	COG3189	MarR family transcriptional regulator
A5955_RS25795	COG3042	response to heat
A5955_RS25800	COG2199	diguanylate cyclase activity
A5955_RS25800	COG2203	Gaf domain
A5955_RS25810	COG2261	transglycosylase associated protein
A5955_RS25820	COG3615	Tellurite resistance protein tehB
A5955_RS25830	COG0583	DNA-binding transcription factor activity
A5955_RS25835	COG0473	3-isopropylmalate dehydrogenase activity
A5955_RS25840	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A5955_RS25845	COG4638	Rieske (2fe-2S)
A5955_RS25850	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A5955_RS25855	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
A5955_RS25860	COG0318	PFAM AMP-dependent synthetase and ligase
A5955_RS25865	COG3065	identical protein binding
A5955_RS25870	COG1214	PFAM Peptidase M22, glycoprotease
A5955_RS25875	COG1199	ATP-dependent helicase activity
A5955_RS25880	COG0251	oxidation-reduction process
A5955_RS25895	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A5955_RS25905	COG1760	l-serine dehydratase
A5955_RS25910	COG2200	EAL domain
A5955_RS25915	COG1253	flavin adenine dinucleotide binding
A5955_RS25925	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A5955_RS25925	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
A5955_RS25930	COG3715	PTS system
A5955_RS25935	COG3716	PTS system mannose fructose sorbose family IID component
A5955_RS25950	COG2226	methyltransferase
A5955_RS25985	COG1414	Transcriptional regulator
A5955_RS25990	COG2814	Major facilitator Superfamily
A5955_RS26000	COG0793	Belongs to the peptidase S41A family
A5955_RS26010	COG1956	GAF domain-containing protein
A5955_RS26015	COG2995	paraquat-inducible protein a
A5955_RS26020	COG3008	intermembrane lipid transfer
A5955_RS26040	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
A5955_RS26055	COG1276	copper resistance
A5955_RS26060	COG2372	response to copper ion
A5955_RS26070	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A5955_RS26075	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A5955_RS26080	COG1770	oligopeptidase
A5955_RS26085	COG2979	Protein of unknown function (DUF533)
A5955_RS26100	COG3141	response to X-ray
A5955_RS26105	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
A5955_RS26110	COG0800	Aldolase
A5955_RS26115	COG0129	dihydroxy-acid dehydratase activity
A5955_RS26120	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
A5955_RS26130	COG1737	Transcriptional regulator
A5955_RS26135	COG0469	pyruvate kinase activity
A5955_RS26140	COG1560	Kdo2-lipid A biosynthetic process
A5955_RS26145	COG0739	heme binding
A5955_RS26150	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
A5955_RS26160	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A5955_RS26185	COG0217	transcriptional regulatory protein
A5955_RS26190	COG0494	nUDIX hydrolase
A5955_RS26200	COG1335	isochorismatase
A5955_RS26205	COG1801	Protein of unknown function DUF72
A5955_RS26210	COG3788	relative of glutathione S-transferase, MAPEG superfamily
A5955_RS26225	COG0243	molybdopterin cofactor binding
A5955_RS26230	COG3005	denitrification pathway
A5955_RS26240	COG3102	Protein conserved in bacteria
A5955_RS26250	COG3755	Protein conserved in bacteria
A5955_RS26260	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A5955_RS26265	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A5955_RS26275	COG0745	RESPONSE REGULATOR receiver
A5955_RS26280	COG2201	protein-glutamate methylesterase activity
A5955_RS26285	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
A5955_RS26290	COG0840	transmembrane signaling receptor activity
A5955_RS26295	COG0840	transmembrane signaling receptor activity
A5955_RS26300	COG0835	chemotaxis
A5955_RS26305	COG2198	Histidine kinase
A5955_RS26305	COG0643	Histidine kinase
A5955_RS26310	COG1360	Flagellar Motor Protein
A5955_RS26315	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
A5955_RS26330	COG0589	response to stress
A5955_RS26340	COG1877	trehalose-phosphatase activity
A5955_RS26345	COG1172	Belongs to the binding-protein-dependent transport system permease family
A5955_RS26350	COG1129	ABC transporter
A5955_RS26355	COG1879	ABC-type sugar transport system periplasmic component
A5955_RS26360	COG1528	Iron-storage protein
A5955_RS26380	COG1528	Iron-storage protein
A5955_RS26390	COG0814	amino acid
A5955_RS26395	COG3012	SEC-C Motif Domain Protein
A5955_RS26395	COG3318	Belongs to the UPF0149 family
A5955_RS26425	COG2197	response regulator
A5955_RS26440	COG2197	response regulator
A5955_RS26445	COG1126	abc transporter atp-binding protein
A5955_RS26450	COG0765	amino acid transport
A5955_RS26460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A5955_RS26470	COG1191	sigma factor activity
A5955_RS26480	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
A5955_RS26485	COG1516	flagellar protein fliS
A5955_RS26495	COG0366	Alpha amylase catalytic
A5955_RS26505	COG2391	methyltransferase activity
A5955_RS26510	COG0425	Belongs to the sulfur carrier protein TusA family
A5955_RS26515	COG2135	peptidase activity
A5955_RS26520	COG0454	-acetyltransferase
A5955_RS26535	COG0454	-acetyltransferase
A5955_RS26555	COG1766	The M ring may be actively involved in energy transduction
A5955_RS26560	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A5955_RS26565	COG1317	bacterial-type flagellum organization
A5955_RS26570	COG1157	protein secretion by the type III secretion system
A5955_RS26575	COG2882	bacterial-type flagellum organization
A5955_RS26580	COG3144	bacterial-type flagellum assembly
A5955_RS26585	COG1580	Controls the rotational direction of flagella during chemotaxis
A5955_RS26590	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A5955_RS26595	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A5955_RS26600	COG3190	flagellar
A5955_RS26605	COG1338	Plays a role in the flagellum-specific transport system
A5955_RS26610	COG1987	bacterial-type flagellum assembly
A5955_RS26615	COG1684	flagellar biosynthetic protein fliR
A5955_RS26620	COG2197	response regulator
A5955_RS26640	COG3706	GGDEF domain
A5955_RS26645	COG5475	Uncharacterized small protein (DUF2158)
A5955_RS26650	COG2354	Protein conserved in bacteria
A5955_RS26655	COG0697	spore germination
A5955_RS26660	COG3727	T/G mismatch-specific endonuclease activity
A5955_RS26665	COG0270	DNA (cytosine-5-)-methyltransferase activity
A5955_RS26670	COG1418	mRNA catabolic process
A5955_RS26680	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
A5955_RS26695	COG2205	protein histidine kinase activity
A5955_RS26700	COG0745	RESPONSE REGULATOR receiver
A5955_RS26705	COG2351	hydroxyisourate hydrolase activity
A5955_RS26720	COG3443	Belongs to the bacterial solute-binding protein 9 family
A5955_RS26725	COG3038	cytochrome b561
A5955_RS26760	COG5301	cellulose 1,4-beta-cellobiosidase activity
A5955_RS26870	COG4220	transposase activity
A5955_RS26885	COG3772	lysozyme
A5955_RS26965	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
A5955_RS26970	COG1403	HNH endonuclease
A5955_RS27050	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A5955_RS27080	COG5301	cellulose 1,4-beta-cellobiosidase activity
A5955_RS27095	COG2032	superoxide dismutase activity
A5955_RS27340	COG1403	HNH endonuclease