locus-tag	class	description
C6W73_RS00025	COG1846	Transcriptional regulator
C6W73_RS00090	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6W73_RS00100	COG0582	viral genome integration into host DNA
C6W73_RS00105	COG1177	transmembrane transport
C6W73_RS00110	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C6W73_RS00120	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
C6W73_RS00125	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C6W73_RS00135	COG4591	ABC-type transport system involved in lipoprotein release permease component
C6W73_RS00140	COG1136	(ABC) transporter
C6W73_RS00145	COG4591	ABC-type transport system involved in lipoprotein release permease component
C6W73_RS00150	COG4763	Acyl-transferase
C6W73_RS00155	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C6W73_RS00160	COG1388	LysM domain
C6W73_RS00160	COG1376	ErfK ybiS ycfS ynhG family protein
C6W73_RS00170	COG1309	transcriptional regulator
C6W73_RS00175	COG3134	Outer membrane lipoprotein
C6W73_RS00185	COG1252	NADH dehydrogenase
C6W73_RS00205	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
C6W73_RS00210	COG5633	Lipoprotein
C6W73_RS00215	COG0537	adenosine 5'-monophosphoramidase activity
C6W73_RS00220	COG4773	Receptor
C6W73_RS00225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6W73_RS00225	COG1263	PTS System
C6W73_RS00230	COG0084	hydrolase, TatD family'
C6W73_RS00245	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C6W73_RS00250	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C6W73_RS00255	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C6W73_RS00265	COG1028	Short-chain dehydrogenase reductase Sdr
C6W73_RS00270	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C6W73_RS00290	COG1399	metal-binding, possibly nucleic acid-binding protein
C6W73_RS00295	COG0424	maF-like protein
C6W73_RS00310	COG1530	ribonuclease E activity
C6W73_RS00315	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C6W73_RS00320	COG1256	bacterial-type flagellum assembly
C6W73_RS00325	COG3951	Flagellar rod assembly protein muramidase FlgJ
C6W73_RS00325	COG1705	Flagellar rod assembly protein muramidase FlgJ
C6W73_RS00340	COG4786	Flagellar basal body rod
C6W73_RS00345	COG4787	bacterial-type flagellum-dependent cell motility
C6W73_RS00350	COG1749	Flagellar hook protein flgE
C6W73_RS00355	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C6W73_RS00360	COG1558	bacterial-type flagellum-dependent cell motility
C6W73_RS00365	COG1815	bacterial-type flagellum-dependent cell motility
C6W73_RS00370	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
C6W73_RS00375	COG2747	anti-sigma28 factor FlgM
C6W73_RS00380	COG3418	PFAM FlgN family protein
C6W73_RS00385	COG0728	peptidoglycan biosynthetic process
C6W73_RS00390	COG0673	inositol 2-dehydrogenase activity
C6W73_RS00400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C6W73_RS00410	COG2999	glutathione oxidoreductase activity
C6W73_RS00450	COG3038	cytochrome b561
C6W73_RS00455	COG2353	YceI-like domain
C6W73_RS00465	COG1560	Kdo2-lipid A biosynthetic process
C6W73_RS00480	COG5645	(Lipo)protein
C6W73_RS00485	COG2943	transferase activity, transferring hexosyl groups
C6W73_RS00510	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C6W73_RS00515	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C6W73_RS00550	COG2197	response regulator
C6W73_RS00565	COG1462	curli production assembly transport component CsgG
C6W73_RS00575	COG3381	protein complex oligomerization
C6W73_RS00605	COG1702	phosphate starvation-inducible protein PhoH
C6W73_RS00610	COG2837	iron assimilation
C6W73_RS00615	COG2822	iron ion transport
C6W73_RS00635	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C6W73_RS00655	COG1309	transcriptional regulator
C6W73_RS00690	COG2233	PERMEase
C6W73_RS00695	COG3729	General stress protein
C6W73_RS00740	COG0243	molybdopterin cofactor binding
C6W73_RS00745	COG3005	denitrification pathway
C6W73_RS00750	COG0745	RESPONSE REGULATOR receiver
C6W73_RS00755	COG1879	ABC-type sugar transport system periplasmic component
C6W73_RS00760	COG2198	Histidine kinase
C6W73_RS00760	COG2205	protein histidine kinase activity
C6W73_RS00760	COG0784	Response regulator, receiver
C6W73_RS00765	COG0348	domain, Protein
C6W73_RS00785	COG1278	Cold shock
C6W73_RS00790	COG1278	Cold shock
C6W73_RS00810	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C6W73_RS00815	COG1596	polysaccharide export
C6W73_RS00820	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C6W73_RS00825	COG3206	protein involved in exopolysaccharide biosynthesis
C6W73_RS00825	COG0489	protein tyrosine kinase activity
C6W73_RS00840	COG1294	oxidase, subunit
C6W73_RS00845	COG1271	oxidase subunit
C6W73_RS00850	COG1773	rubredoxin
C6W73_RS00855	COG1999	signal sequence binding
C6W73_RS00860	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C6W73_RS00865	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
C6W73_RS00870	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
C6W73_RS00875	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
C6W73_RS00885	COG0670	Belongs to the BI1 family
C6W73_RS00890	COG2920	part of a sulfur-relay system
C6W73_RS00895	COG1254	Belongs to the acylphosphatase family
C6W73_RS00910	COG1832	CoA-binding protein
C6W73_RS00925	COG0210	DNA helicase
C6W73_RS00930	COG3304	Inner membrane component domain
C6W73_RS00935	COG1289	transmembrane transporter activity
C6W73_RS00940	COG3070	regulator of competence-specific genes
C6W73_RS00965	COG1067	ATP-dependent peptidase activity
C6W73_RS00975	COG3130	regulation of translation
C6W73_RS00980	COG3009	Protein conserved in bacteria
C6W73_RS00985	COG3008	intermembrane lipid transfer
C6W73_RS00985	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C6W73_RS00990	COG2995	paraquat-inducible protein a
C6W73_RS00995	COG0488	(ABC) transporter
C6W73_RS01005	COG3217	Mosc domain protein beta barrel domain protein
C6W73_RS01005	COG0633	Ferredoxin
C6W73_RS01020	COG3121	Chaperone
C6W73_RS01025	COG3539	Fimbrial protein
C6W73_RS01030	COG3539	Fimbrial protein
C6W73_RS01035	COG3539	Fimbrial protein
C6W73_RS01040	COG3188	usher protein
C6W73_RS01045	COG3121	Chaperone
C6W73_RS01050	COG3539	Fimbrial protein
C6W73_RS01060	COG0431	NADPH-dependent FMN reductase
C6W73_RS01065	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C6W73_RS01075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C6W73_RS01085	COG0308	aminopeptidase N
C6W73_RS01110	COG1448	Aminotransferase
C6W73_RS01120	COG3547	Transposase (IS116 IS110 IS902 family)
C6W73_RS01125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C6W73_RS01130	COG3108	Peptidase M15
C6W73_RS01140	COG2989	Protein conserved in bacteria
C6W73_RS01150	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
C6W73_RS01160	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C6W73_RS01165	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C6W73_RS01170	COG3173	Aminoglycoside phosphotransferase
C6W73_RS01185	COG3214	Protein conserved in bacteria
C6W73_RS01195	COG1132	(ABC) transporter
C6W73_RS01200	COG0658	competence protein
C6W73_RS01200	COG2333	competence protein COMEC
C6W73_RS01210	COG0539	negative regulation of cytoplasmic translation
C6W73_RS01220	COG0501	Belongs to the peptidase M48B family
C6W73_RS01235	COG2323	membrane
C6W73_RS01240	COG1944	ATP diphosphatase activity
C6W73_RS01245	COG2116	formate transmembrane transporter activity
C6W73_RS01250	COG1882	Formate acetyltransferase
C6W73_RS01255	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C6W73_RS01260	COG2249	NAD(P)H dehydrogenase (quinone) activity
C6W73_RS01265	COG0583	DNA-binding transcription factor activity
C6W73_RS01270	COG0531	amino acid
C6W73_RS01280	COG1335	isochorismatase
C6W73_RS01285	COG3302	dmso reductase anchor subunit
C6W73_RS01290	COG0437	4 iron, 4 sulfur cluster binding
C6W73_RS01295	COG0243	molybdopterin cofactor binding
C6W73_RS01305	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C6W73_RS01320	COG1522	sequence-specific DNA binding
C6W73_RS01330	COG0492	ferredoxin-NADP+ reductase activity
C6W73_RS01335	COG4988	ABC transporter
C6W73_RS01340	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C6W73_RS01385	COG1203	CRISPR-associated helicase, Cas3
C6W73_RS01390	COG1518	maintenance of DNA repeat elements
C6W73_RS01400	COG0542	response to heat
C6W73_RS01410	COG1278	Cold shock
C6W73_RS01415	COG0577	efflux transmembrane transporter activity
C6W73_RS01415	COG1136	(ABC) transporter
C6W73_RS01420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6W73_RS01425	COG2990	Protein conserved in bacteria
C6W73_RS01430	COG3593	DNA synthesis involved in DNA repair
C6W73_RS01445	COG2431	L-lysine efflux transmembrane transporter activity
C6W73_RS01455	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C6W73_RS01460	COG0028	Belongs to the TPP enzyme family
C6W73_RS01465	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
C6W73_RS01470	COG0702	epimerase
C6W73_RS01475	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C6W73_RS01480	COG3023	N-Acetylmuramoyl-L-alanine amidase
C6W73_RS01495	COG1126	abc transporter atp-binding protein
C6W73_RS01500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6W73_RS01505	COG4215	(ABC) transporter
C6W73_RS01510	COG4160	amino acid transport
C6W73_RS01515	COG3547	Transposase (IS116 IS110 IS902 family)
C6W73_RS01525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6W73_RS01540	COG1177	transmembrane transport
C6W73_RS01545	COG1176	ABC-type spermidine putrescine transport system, permease component I
C6W73_RS01550	COG3842	ATPase activity
C6W73_RS01555	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C6W73_RS01575	COG0778	Nitroreductase
C6W73_RS01585	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C6W73_RS01640	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C6W73_RS01655	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C6W73_RS01745	COG4695	Portal protein
C6W73_RS01790	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C6W73_RS01830	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
C6W73_RS01840	COG3226	Transcriptional regulator
C6W73_RS01845	COG0738	Major facilitator superfamily
C6W73_RS01850	COG0561	phosphatase activity
C6W73_RS01860	COG2814	Major facilitator Superfamily
C6W73_RS01865	COG0671	phosphoesterase, PA-phosphatase related
C6W73_RS01870	COG1349	DNA-binding transcription factor activity
C6W73_RS01875	COG1686	Belongs to the peptidase S11 family
C6W73_RS01880	COG0625	glutathione transferase activity
C6W73_RS01885	COG2133	pyrroloquinoline quinone binding
C6W73_RS01900	COG2199	diguanylate cyclase activity
C6W73_RS01905	COG2200	EAL domain
C6W73_RS01930	COG1446	asparaginase
C6W73_RS01935	COG0303	'Molybdopterin
C6W73_RS01940	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C6W73_RS01945	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C6W73_RS01950	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C6W73_RS01955	COG1882	Formate acetyltransferase
C6W73_RS01960	COG0561	phosphatase activity
C6W73_RS01970	COG3547	Transposase (IS116 IS110 IS902 family)
C6W73_RS01980	COG0488	(ABC) transporter
C6W73_RS01985	COG1376	ErfK ybiS ycfS ynhG family protein
C6W73_RS01990	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C6W73_RS01995	COG1321	iron dependent repressor
C6W73_RS02005	COG2194	sulfuric ester hydrolase activity
C6W73_RS02010	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
C6W73_RS02015	COG5006	permease, DMT superfamily
C6W73_RS02035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6W73_RS02040	COG0765	amino acid transport
C6W73_RS02045	COG1126	abc transporter atp-binding protein
C6W73_RS02050	COG0668	transmembrane transport
C6W73_RS02065	COG4774	siderophore transport
C6W73_RS02075	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C6W73_RS02085	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
C6W73_RS02090	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C6W73_RS02095	COG1199	ATP-dependent helicase activity
C6W73_RS02105	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
C6W73_RS02110	COG0513	Belongs to the DEAD box helicase family
C6W73_RS02115	COG1309	transcriptional regulator
C6W73_RS02125	COG1131	(ABC) transporter
C6W73_RS02130	COG0842	Transport permease protein
C6W73_RS02135	COG0842	Transport permease protein
C6W73_RS02145	COG3568	Endonuclease Exonuclease Phosphatase
C6W73_RS02150	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C6W73_RS02155	COG0392	lysyltransferase activity
C6W73_RS02160	COG0670	Belongs to the BI1 family
C6W73_RS02165	COG0670	Belongs to the BI1 family
C6W73_RS02170	COG0314	molybdopterin synthase activity
C6W73_RS02175	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C6W73_RS02185	COG0521	Mo-molybdopterin cofactor biosynthetic process
C6W73_RS02195	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C6W73_RS02205	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C6W73_RS02210	COG2226	methyltransferase
C6W73_RS02230	COG1881	PFAM PEBP family protein
C6W73_RS02240	COG4677	pectinesterase activity
C6W73_RS02245	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C6W73_RS02250	COG0471	metal ion transport
C6W73_RS02255	COG2828	Protein conserved in bacteria
C6W73_RS02260	COG0583	DNA-binding transcription factor activity
C6W73_RS02270	COG0561	phosphatase activity
C6W73_RS02280	COG4149	molybdate abc transporter
C6W73_RS02285	COG0725	ABC transporter, periplasmic molybdate-binding protein
C6W73_RS02300	COG3585	molybdate ion transport
C6W73_RS02300	COG2005	Transcriptional regulator
C6W73_RS02305	COG1119	ATPase activity
C6W73_RS02310	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C6W73_RS02315	COG1085	galactose-1-phosphate uridylyltransferase
C6W73_RS02325	COG2017	converts alpha-aldose to the beta-anomer
C6W73_RS02335	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C6W73_RS02350	COG1230	cation diffusion facilitator family transporter
C6W73_RS02355	COG3201	nicotinamide mononucleotide transporter
C6W73_RS02400	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
C6W73_RS02405	COG2885	chlorophyll binding
C6W73_RS02415	COG3064	Membrane
C6W73_RS02420	COG0848	biopolymer transport protein
C6W73_RS02425	COG0811	peptide transport
C6W73_RS02430	COG0824	Thioesterase
C6W73_RS02435	COG3790	cyd operon protein YbgE
C6W73_RS02440	COG4890	Cyd operon protein YbgT
C6W73_RS02445	COG1294	oxidase, subunit
C6W73_RS02450	COG1271	oxidase subunit
C6W73_RS02460	COG0383	alpha-mannosidase activity
C6W73_RS02465	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6W73_RS02465	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6W73_RS02465	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6W73_RS02470	COG2188	Transcriptional regulator
C6W73_RS02475	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C6W73_RS02485	COG0508	dehydrogenase complex catalyzes the overall conversion of
C6W73_RS02490	COG0567	Dehydrogenase, E1 component
C6W73_RS02495	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C6W73_RS02500	COG1053	succinate dehydrogenase
C6W73_RS02505	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
C6W73_RS02510	COG2009	succinate dehydrogenase
C6W73_RS02525	COG0372	Belongs to the citrate synthase family
C6W73_RS02530	COG3539	Fimbrial protein
C6W73_RS02535	COG3188	usher protein
C6W73_RS02540	COG3121	Chaperone
C6W73_RS02545	COG3539	Fimbrial protein
C6W73_RS02550	COG3180	Ammonia monooxygenase
C6W73_RS02565	COG1984	allophanate hydrolase subunit 2
C6W73_RS02570	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C6W73_RS02575	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C6W73_RS02585	COG0415	Belongs to the DNA photolyase family
C6W73_RS02590	COG3272	Protein of unknown function (DUF1722)
C6W73_RS02620	COG3209	COG3209 Rhs family protein
C6W73_RS02655	COG0745	RESPONSE REGULATOR receiver
C6W73_RS02670	COG1982	Orn Lys Arg decarboxylase major
C6W73_RS02675	COG0531	amino acid
C6W73_RS02680	COG0033	Phosphoglucomutase
C6W73_RS02685	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
C6W73_RS02690	COG0596	Alpha beta hydrolase
C6W73_RS02700	COG0716	FMN binding
C6W73_RS02710	COG0735	belongs to the Fur family
C6W73_RS02735	COG2190	(PTS) system
C6W73_RS02735	COG1263	PTS System
C6W73_RS02735	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6W73_RS02745	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C6W73_RS02750	COG1846	Transcriptional regulator
C6W73_RS02750	COG1940	carbohydrate kinase activity
C6W73_RS02755	COG0647	UMP catabolic process
C6W73_RS02765	COG0367	asparagine synthase
C6W73_RS02810	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C6W73_RS02820	COG1702	phosphate starvation-inducible protein PhoH
C6W73_RS02830	COG4535	Mg2 and Co2 transporter CorC
C6W73_RS02835	COG0815	Transfers the fatty acyl group on membrane lipoproteins
C6W73_RS02850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6W73_RS02855	COG0765	amino acid transport
C6W73_RS02860	COG0765	amino acid transport
C6W73_RS02865	COG1126	abc transporter atp-binding protein
C6W73_RS02875	COG0443	Heat shock 70 kDa protein
C6W73_RS02880	COG2214	Heat shock protein DnaJ domain protein
C6W73_RS02890	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C6W73_RS02895	COG2214	Heat shock protein DnaJ domain protein
C6W73_RS02905	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C6W73_RS02910	COG2888	peptidyl-tyrosine sulfation
C6W73_RS02925	COG1466	dna polymerase III delta subunit
C6W73_RS02935	COG0406	alpha-ribazole phosphatase activity
C6W73_RS02940	COG0799	negative regulation of ribosome biogenesis
C6W73_RS02950	COG0768	penicillin binding
C6W73_RS02955	COG0772	Belongs to the SEDS family
C6W73_RS02960	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C6W73_RS02965	COG1686	Belongs to the peptidase S11 family
C6W73_RS02985	COG0583	DNA-binding transcription factor activity
C6W73_RS03000	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C6W73_RS03005	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C6W73_RS03030	COG3069	C4-dicarboxylate transmembrane transporter activity
C6W73_RS03035	COG4565	transcriptional regulatory protein
C6W73_RS03040	COG3290	protein histidine kinase activity
C6W73_RS03045	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
C6W73_RS03055	COG2301	Belongs to the HpcH HpaI aldolase family
C6W73_RS03060	COG3051	citrate lyase alpha subunit
C6W73_RS03075	COG0471	metal ion transport
C6W73_RS03080	COG3719	Belongs to the RNase T2 family
C6W73_RS03090	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C6W73_RS03100	COG1063	alcohol dehydrogenase
C6W73_RS03105	COG0589	response to stress
C6W73_RS03110	COG3634	alkyl hydroperoxide reductase activity
C6W73_RS03115	COG0450	alkyl hydroperoxide reductase
C6W73_RS03120	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C6W73_RS03130	COG0583	DNA-binding transcription factor activity
C6W73_RS03135	COG3969	phosphoadenosine phosphosulfate
C6W73_RS03140	COG1475	DNA binding
C6W73_RS03145	COG0436	Aminotransferase
C6W73_RS03150	COG0371	Dehydrogenase
C6W73_RS03155	COG2879	small protein
C6W73_RS03160	COG1966	Carbon starvation protein
C6W73_RS03165	COG2050	protein possibly involved in aromatic compounds catabolism
C6W73_RS03170	COG1028	Short-chain dehydrogenase reductase Sdr
C6W73_RS03175	COG3433	isochorismatase activity
C6W73_RS03175	COG1535	isochorismatase
C6W73_RS03180	COG1021	2,3-dihydroxybenzoate-AMP ligase
C6W73_RS03185	COG1169	isochorismate synthase
C6W73_RS03195	COG4592	Periplasmic binding protein
C6W73_RS03205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6W73_RS03210	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6W73_RS03215	COG1120	ATPase activity
C6W73_RS03220	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
C6W73_RS03225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C6W73_RS03225	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
C6W73_RS03230	COG3251	PFAM MbtH domain protein
C6W73_RS03235	COG2382	esterase
C6W73_RS03245	COG4771	TonB-dependent receptor
C6W73_RS03250	COG2977	Belongs to the P-Pant transferase superfamily
C6W73_RS03285	COG2315	Protein conserved in bacteria
C6W73_RS03290	COG0778	Nitroreductase
C6W73_RS03295	COG0668	transmembrane transport
C6W73_RS03300	COG1113	amino acid transport
C6W73_RS03310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6W73_RS03315	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6W73_RS03320	COG1538	Outer membrane efflux protein
C6W73_RS03330	COG0745	RESPONSE REGULATOR receiver
C6W73_RS03335	COG5002	protein histidine kinase activity
C6W73_RS03340	COG3501	Rhs element vgr protein
C6W73_RS03350	COG3209	COG3209 Rhs family protein
C6W73_RS03350	COG4104	PAAR repeat-containing protein
C6W73_RS03375	COG5433	transposase activity
C6W73_RS03380	COG1215	transferase activity, transferring glycosyl groups
C6W73_RS03385	COG4783	chaperone-mediated protein folding
C6W73_RS03400	COG2207	Transcriptional regulator
C6W73_RS03415	COG4571	Outer membrane protease
C6W73_RS03430	COG0500	methyltransferase
C6W73_RS03440	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C6W73_RS03445	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C6W73_RS03485	COG1196	nuclear chromosome segregation
C6W73_RS03535	COG1030	water channel activity
C6W73_RS03555	COG4220	transposase activity
C6W73_RS03580	COG3772	lysozyme
C6W73_RS03615	COG4372	Transposase
C6W73_RS03620	COG3436	PFAM IS66 Orf2 family protein
C6W73_RS03655	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C6W73_RS03660	COG2076	Multidrug Resistance protein
C6W73_RS03750	COG0582	viral genome integration into host DNA
C6W73_RS03760	COG2197	response regulator
C6W73_RS03765	COG3539	Fimbrial protein
C6W73_RS03770	COG3539	Fimbrial protein
C6W73_RS03775	COG3188	usher protein
C6W73_RS03780	COG3121	Chaperone
C6W73_RS03785	COG3539	Fimbrial protein
C6W73_RS03795	COG2501	S4 domain
C6W73_RS03800	COG1988	membrane-bound metal-dependent
C6W73_RS03810	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C6W73_RS03825	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C6W73_RS03830	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C6W73_RS03835	COG0549	Belongs to the carbamate kinase family
C6W73_RS03845	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C6W73_RS03850	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C6W73_RS03855	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
C6W73_RS03860	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C6W73_RS03865	COG3257	ureidoglycine aminohydrolase activity
C6W73_RS03870	COG1929	Belongs to the glycerate kinase type-1 family
C6W73_RS03875	COG2233	PERMEase
C6W73_RS03885	COG1953	Uracil, thiamine, allantoin
C6W73_RS03890	COG2084	Dehydrogenase
C6W73_RS03895	COG3622	Belongs to the hyi family
C6W73_RS03900	COG3960	tartronate-semialdehyde synthase activity
C6W73_RS03905	COG1414	Transcriptional regulator
C6W73_RS03915	COG0583	DNA-binding transcription factor activity
C6W73_RS03940	COG3209	COG3209 Rhs family protein
C6W73_RS03945	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
C6W73_RS03950	COG4181	ATPase activity
C6W73_RS03955	COG2755	lipolytic protein G-D-S-L family
C6W73_RS03960	COG0300	oxidoreductase activity
C6W73_RS03965	COG3118	belongs to the thioredoxin family
C6W73_RS03970	COG0390	transport system, permease component
C6W73_RS03975	COG4619	ABC transporter
C6W73_RS03980	COG0330	HflC and HflK could
C6W73_RS03985	COG1585	Membrane protein implicated in regulation of membrane protease activity
C6W73_RS03990	COG0789	Transcriptional regulator
C6W73_RS03995	COG0531	amino acid
C6W73_RS04005	COG2217	Heavy metal translocating P-type atpase
C6W73_RS04010	COG3093	addiction module antidote protein HigA
C6W73_RS04020	COG3735	TraB family
C6W73_RS04030	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C6W73_RS04035	COG0737	Belongs to the 5'-nucleotidase family
C6W73_RS04045	COG2223	nitrite transmembrane transporter activity
C6W73_RS04050	COG4651	solute:proton antiporter activity
C6W73_RS04050	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C6W73_RS04055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6W73_RS04095	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C6W73_RS04110	COG2832	Protein of unknown function (DUF454)
C6W73_RS04115	COG3923	Primosomal replication protein n
C6W73_RS04125	COG3264	Mechanosensitive ion channel
C6W73_RS04125	COG1196	nuclear chromosome segregation
C6W73_RS04135	COG1309	transcriptional regulator
C6W73_RS04140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6W73_RS04145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C6W73_RS04160	COG0110	maltose O-acetyltransferase activity
C6W73_RS04170	COG4943	cyclic-guanylate-specific phosphodiesterase activity
C6W73_RS04175	COG5507	3-demethylubiquinone-9 3-methyltransferase
C6W73_RS04185	COG3695	enzyme binding
C6W73_RS04190	COG3126	Type III secretion system lipoprotein chaperone (YscW)
C6W73_RS04195	COG1946	Acyl-CoA thioesterase
C6W73_RS04200	COG0004	ammonium transporteR
C6W73_RS04205	COG0347	Belongs to the P(II) protein family
C6W73_RS04210	COG1132	(ABC) transporter
C6W73_RS04215	COG1132	(ABC) transporter
C6W73_RS04220	COG1522	sequence-specific DNA binding
C6W73_RS04230	COG4533	DNA binding
C6W73_RS04240	COG0824	Thioesterase
C6W73_RS04245	COG1555	photosystem II stabilization
C6W73_RS04250	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C6W73_RS04255	COG0776	regulation of translation
C6W73_RS04260	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C6W73_RS04285	COG0271	Belongs to the BolA IbaG family
C6W73_RS04290	COG3056	Lipoprotein
C6W73_RS04295	COG2223	nitrite transmembrane transporter activity
C6W73_RS04300	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C6W73_RS04305	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C6W73_RS04310	COG1845	cytochrome c oxidase, subunit III
C6W73_RS04315	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C6W73_RS04340	COG2814	Major facilitator Superfamily
C6W73_RS04350	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C6W73_RS04355	COG0693	protein deglycase activity
C6W73_RS04375	COG0142	geranyltranstransferase activity
C6W73_RS04385	COG0667	Aldo Keto reductase
C6W73_RS04390	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C6W73_RS04410	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C6W73_RS04410	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C6W73_RS04420	COG4238	major outer membrane lipoprotein
C6W73_RS04425	COG3248	Nucleoside-binding outer membrane protein
C6W73_RS04430	COG1403	HNH endonuclease
C6W73_RS04435	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C6W73_RS04440	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C6W73_RS04445	COG1862	Preprotein translocase
C6W73_RS04465	COG0366	Alpha amylase catalytic
C6W73_RS04470	COG1113	amino acid transport
C6W73_RS04475	COG1114	Component of the transport system for branched-chain amino acids
C6W73_RS04480	COG5002	protein histidine kinase activity
C6W73_RS04485	COG0745	RESPONSE REGULATOR receiver
C6W73_RS04490	COG0420	3'-5' exonuclease activity
C6W73_RS04495	COG0419	ATPase involved in DNA repair
C6W73_RS04500	COG2814	Major facilitator Superfamily
C6W73_RS04505	COG1940	carbohydrate kinase activity
C6W73_RS04530	COG4126	flavin adenine dinucleotide binding
C6W73_RS04555	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C6W73_RS04560	COG3706	GGDEF domain
C6W73_RS04570	COG1785	Belongs to the alkaline phosphatase family
C6W73_RS04585	COG1181	Belongs to the D-alanine--D-alanine ligase family
C6W73_RS04610	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
C6W73_RS04620	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C6W73_RS04625	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C6W73_RS04630	COG3468	outer membrane autotransporter barrel domain protein
C6W73_RS04640	COG0113	porphobilinogen synthase activity
C6W73_RS04645	COG2175	clavaminate synthase activity
C6W73_RS04650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C6W73_RS04660	COG4521	taurine ABC transporter
C6W73_RS04670	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C6W73_RS04675	COG1215	transferase activity, transferring glycosyl groups
C6W73_RS04710	COG3122	Protein conserved in bacteria
C6W73_RS04715	COG2814	Major facilitator Superfamily
C6W73_RS04750	COG1414	Transcriptional regulator
C6W73_RS04755	COG1609	Transcriptional regulator
C6W73_RS04770	COG2223	nitrite transmembrane transporter activity
C6W73_RS04775	COG0110	maltose O-acetyltransferase activity
C6W73_RS04785	COG3547	Transposase (IS116 IS110 IS902 family)
C6W73_RS04790	COG0402	S-adenosylhomocysteine deaminase activity
C6W73_RS04795	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C6W73_RS04800	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C6W73_RS04805	COG2079	MmgE PrpD family protein
C6W73_RS04810	COG0372	Belongs to the citrate synthase family
C6W73_RS04815	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C6W73_RS04820	COG3829	transcription factor binding
C6W73_RS04830	COG1280	lysine exporter protein (LysE YggA)
C6W73_RS04845	COG1064	alcohol dehydrogenase
C6W73_RS04855	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6W73_RS04860	COG1129	ABC transporter
C6W73_RS04865	COG1879	ABC-type sugar transport system periplasmic component
C6W73_RS04875	COG0402	S-adenosylhomocysteine deaminase activity
C6W73_RS04880	COG0549	Belongs to the carbamate kinase family
C6W73_RS04885	COG1304	FMN binding
C6W73_RS04890	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C6W73_RS04900	COG0666	response to abiotic stimulus
C6W73_RS04915	COG0583	DNA-binding transcription factor activity
C6W73_RS04920	COG2200	EAL domain
C6W73_RS04920	COG2771	luxR family
C6W73_RS04930	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C6W73_RS04970	COG1556	Lactate utilization protein
C6W73_RS04975	COG1139	Iron-sulfur cluster binding protein
C6W73_RS04980	COG0247	lactate metabolic process
C6W73_RS04985	COG2207	Transcriptional regulator
C6W73_RS04990	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C6W73_RS05000	COG3059	membrane
C6W73_RS05005	COG0656	L-ascorbic acid biosynthetic process
C6W73_RS05010	COG3708	Transcriptional regulator
C6W73_RS05010	COG2207	Transcriptional regulator
C6W73_RS05015	COG1388	LysM domain
C6W73_RS05070	COG3188	usher protein
C6W73_RS05080	COG3121	Chaperone
C6W73_RS05085	COG0727	PFAM Uncharacterised protein family (UPF0153)
C6W73_RS05095	COG3477	response to acidic pH
C6W73_RS05105	COG2080	2 iron, 2 sulfur cluster binding
C6W73_RS05110	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C6W73_RS05115	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C6W73_RS05120	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C6W73_RS05125	COG0583	DNA-binding transcription factor activity
C6W73_RS05145	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C6W73_RS05165	COG2195	Cleaves the N-terminal amino acid of tripeptides
C6W73_RS05170	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
C6W73_RS05175	COG1690	Belongs to the RtcB family
C6W73_RS05185	COG0454	-acetyltransferase
C6W73_RS05215	COG0791	NLP P60 protein
C6W73_RS05220	COG3077	Addiction module antitoxin, RelB DinJ family
C6W73_RS05225	COG3041	Addiction module toxin RelE StbE family
C6W73_RS05230	COG3034	peptidoglycan biosynthetic process
C6W73_RS05235	COG0121	glutamine amidotransferase
C6W73_RS05245	COG1960	acyl-CoA dehydrogenase activity
C6W73_RS05255	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C6W73_RS05305	COG3209	COG3209 Rhs family protein
C6W73_RS05400	COG3157	Type VI secretion system effector, Hcp
C6W73_RS05405	COG4104	PAAR repeat-containing protein
C6W73_RS05430	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6W73_RS05440	COG2226	methyltransferase
C6W73_RS05450	COG1388	LysM domain
C6W73_RS05450	COG0741	lytic transglycosylase activity
C6W73_RS05455	COG2226	methyltransferase
C6W73_RS05465	COG0583	DNA-binding transcription factor activity
C6W73_RS05470	COG0656	L-ascorbic acid biosynthetic process
C6W73_RS05505	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C6W73_RS05510	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C6W73_RS05515	COG2011	ABC-type metal ion transport system permease component
C6W73_RS05520	COG1464	Belongs to the NlpA lipoprotein family
C6W73_RS05530	COG1720	tRNA m6t6A37 methyltransferase activity
C6W73_RS05540	COG0791	NLP P60 protein
C6W73_RS05545	COG3547	Transposase (IS116 IS110 IS902 family)
C6W73_RS05555	COG3015	lipoprotein NlpE involved in copper resistance
C6W73_RS05560	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
C6W73_RS05565	COG4681	YaeQ
C6W73_RS05575	COG4568	rho-dependent transcription termination
C6W73_RS05585	COG0346	lactoylglutathione lyase activity
C6W73_RS05590	COG1982	Orn Lys Arg decarboxylase major
C6W73_RS05600	COG0587	DNA-directed DNA polymerase activity
C6W73_RS05625	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C6W73_RS05630	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
C6W73_RS05640	COG0750	zinc metalloprotease
C6W73_RS05645	COG0575	Belongs to the CDS family
C6W73_RS05650	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C6W73_RS05655	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C6W73_RS05690	COG0024	Methionine aminopeptidase
C6W73_RS05710	COG3835	regulator
C6W73_RS05715	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C6W73_RS05735	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C6W73_RS05740	COG2860	membrane
C6W73_RS05760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6W73_RS05765	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C6W73_RS05770	COG1120	ATPase activity
C6W73_RS05775	COG4774	siderophore transport
C6W73_RS05780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C6W73_RS05790	COG1643	Atp-dependent helicase
C6W73_RS05795	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C6W73_RS05805	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C6W73_RS05815	COG0617	tRNA 3'-terminal CCA addition
C6W73_RS05820	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C6W73_RS05825	COG3539	Fimbrial protein
C6W73_RS05830	COG3121	Chaperone
C6W73_RS05835	COG3188	usher protein
C6W73_RS05840	COG3188	usher protein
C6W73_RS05845	COG3539	Fimbrial protein
C6W73_RS05850	COG3539	Fimbrial protein
C6W73_RS05855	COG3539	Fimbrial protein
C6W73_RS05860	COG3539	Fimbrial protein
C6W73_RS05875	COG5464	transposase or invertase
C6W73_RS05895	COG0726	polysaccharide deacetylase
C6W73_RS05900	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6W73_RS05905	COG0842	Transport permease protein
C6W73_RS05910	COG1131	(ABC) transporter
C6W73_RS05915	COG0288	reversible hydration of carbon dioxide
C6W73_RS05920	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
C6W73_RS05925	COG4993	Dehydrogenase
C6W73_RS05930	COG2132	Multicopper oxidase
C6W73_RS05955	COG1049	propionate catabolic process, 2-methylcitrate cycle
C6W73_RS05965	COG3064	Membrane
C6W73_RS05970	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C6W73_RS05975	COG0508	dehydrogenase complex catalyzes the overall conversion of
C6W73_RS05980	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
C6W73_RS05990	COG2186	Transcriptional regulator
C6W73_RS05995	COG1113	amino acid transport
C6W73_RS06000	COG3725	Membrane protein required for beta-lactamase induction
C6W73_RS06005	COG3023	N-Acetylmuramoyl-L-alanine amidase
C6W73_RS06010	COG0157	Belongs to the NadC ModD family
C6W73_RS06020	COG4969	Belongs to the N-Me-Phe pilin family
C6W73_RS06025	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C6W73_RS06030	COG1459	type II secretion system
C6W73_RS06040	COG0237	dephospho-CoA kinase activity
C6W73_RS06055	COG0494	nUDIX hydrolase
C6W73_RS06075	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C6W73_RS06080	COG0849	cell division
C6W73_RS06085	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C6W73_RS06090	COG1181	Belongs to the D-alanine--D-alanine ligase family
C6W73_RS06105	COG0772	Belongs to the SEDS family
C6W73_RS06120	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C6W73_RS06125	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C6W73_RS06130	COG0768	penicillin binding
C6W73_RS06135	COG3116	cell division
C6W73_RS06160	COG1609	Transcriptional regulator
C6W73_RS06170	COG0440	acetolactate synthase activity
C6W73_RS06175	COG0028	Belongs to the TPP enzyme family
C6W73_RS06180	COG0583	DNA-binding transcription factor activity
C6W73_RS06195	COG0473	3-isopropylmalate dehydrogenase activity
C6W73_RS06210	COG2814	Major facilitator Superfamily
C6W73_RS06225	COG4143	(ABC) transporter
C6W73_RS06230	COG1178	ABC-type Fe3 transport system permease component
C6W73_RS06240	COG0586	Pfam SNARE associated Golgi protein
C6W73_RS06245	COG4977	sequence-specific DNA binding
C6W73_RS06265	COG0235	Class ii aldolase
C6W73_RS06270	COG0417	DNA replication proofreading
C6W73_RS06280	COG0564	pseudouridine synthase activity
C6W73_RS06285	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
C6W73_RS06290	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
C6W73_RS06295	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C6W73_RS06335	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C6W73_RS06355	COG2271	Major facilitator Superfamily
C6W73_RS06360	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C6W73_RS06365	COG0644	oxidoreductase
C6W73_RS06420	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C6W73_RS06425	COG0505	Belongs to the CarA family
C6W73_RS06450	COG1047	Peptidyl-prolyl cis-trans
C6W73_RS06465	COG0196	riboflavin kinase activity
C6W73_RS06495	COG0583	DNA-binding transcription factor activity
C6W73_RS06525	COG4735	regulation of single-species biofilm formation
C6W73_RS06530	COG1584	GPR1 FUN34 yaaH family protein
C6W73_RS06535	COG0521	Mo-molybdopterin cofactor biosynthetic process
C6W73_RS06540	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C6W73_RS06545	COG1115	amino acid carrier protein
C6W73_RS06555	COG3547	Transposase (IS116 IS110 IS902 family)
C6W73_RS06570	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C6W73_RS06580	COG0460	homoserine dehydrogenase
C6W73_RS06580	COG0527	aspartate kinase activity
C6W73_RS06590	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
C6W73_RS06600	COG0745	RESPONSE REGULATOR receiver
C6W73_RS06605	COG4452	Inner membrane protein CreD
C6W73_RS06610	COG2205	protein histidine kinase activity
C6W73_RS06615	COG0745	RESPONSE REGULATOR receiver
C6W73_RS06625	COG3708	Transcriptional regulator
C6W73_RS06625	COG2207	Transcriptional regulator
C6W73_RS06645	COG0741	lytic transglycosylase activity
C6W73_RS06655	COG0488	(ABC) transporter
C6W73_RS06660	COG3172	ATPase kinase involved in NAD metabolism
C6W73_RS06660	COG1056	cytidyltransferase-related domain
C6W73_RS06665	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C6W73_RS06670	COG0560	Phosphoserine phosphatase
C6W73_RS06675	COG3726	membrane protein affecting hemolysin expression
C6W73_RS06705	COG1328	CTP reductase activity
C6W73_RS06710	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C6W73_RS06715	COG0084	hydrolase, TatD family'
C6W73_RS06720	COG4667	esterase of the alpha-beta hydrolase superfamily
C6W73_RS06730	COG2823	Periplasmic or secreted lipoprotein
C6W73_RS06740	COG1011	Hydrolase
C6W73_RS06745	COG0456	acetyltransferase
C6W73_RS06750	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
C6W73_RS06780	COG4114	ferric iron reductase
C6W73_RS06785	COG2197	response regulator
C6W73_RS06790	COG2197	response regulator
C6W73_RS06795	COG2966	Psort location CytoplasmicMembrane, score
C6W73_RS06810	COG1484	DNA-dependent DNA replication
C6W73_RS06825	COG1063	alcohol dehydrogenase
C6W73_RS06830	COG1802	Transcriptional regulator
C6W73_RS06835	COG2271	Major facilitator Superfamily
C6W73_RS06840	COG0840	transmembrane signaling receptor activity
C6W73_RS06845	COG1846	Transcriptional regulator
C6W73_RS06850	COG0179	Fumarylacetoacetate (FAA) hydrolase
C6W73_RS06855	COG1012	belongs to the aldehyde dehydrogenase family
C6W73_RS06860	COG3384	dioxygenase
C6W73_RS06870	COG3971	2-oxopent-4-enoate hydratase activity
C6W73_RS06890	COG2368	4-hydroxyphenylacetate
C6W73_RS06895	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C6W73_RS06905	COG1966	Carbon starvation protein
C6W73_RS06910	COG2879	small protein
C6W73_RS06915	COG0523	cobalamin synthesis protein
C6W73_RS06925	COG5457	Domain of unknown function (DUF1127)
C6W73_RS06930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C6W73_RS06945	COG2814	Major facilitator Superfamily
C6W73_RS06950	COG2733	membrane
C6W73_RS06955	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
C6W73_RS06960	COG1924	4 iron, 4 sulfur cluster binding
C6W73_RS06975	COG0477	Major facilitator Superfamily
C6W73_RS06990	COG3366	ferrous iron transmembrane transporter activity
C6W73_RS06995	COG0700	Nucleoside recognition
C6W73_RS07000	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C6W73_RS07005	COG0583	DNA-binding transcription factor activity
C6W73_RS07025	COG2186	Transcriptional regulator
C6W73_RS07035	COG0246	Mannitol dehydrogenase
C6W73_RS07050	COG2610	gluconate transmembrane transporter activity
C6W73_RS07055	COG3539	Fimbrial protein
C6W73_RS07060	COG3539	Fimbrial protein
C6W73_RS07065	COG3539	Fimbrial protein
C6W73_RS07070	COG3188	usher protein
C6W73_RS07075	COG3121	Chaperone
C6W73_RS07080	COG3539	Fimbrial protein
C6W73_RS07095	COG4974	Belongs to the 'phage' integrase family
C6W73_RS07100	COG0582	viral genome integration into host DNA
C6W73_RS07115	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
C6W73_RS07120	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
C6W73_RS07200	COG0582	viral genome integration into host DNA
C6W73_RS07210	COG1064	alcohol dehydrogenase
C6W73_RS07215	COG0433	COG0433 Predicted ATPase
C6W73_RS07220	COG0795	lipopolysaccharide-transporting ATPase activity
C6W73_RS07225	COG0795	lipopolysaccharide-transporting ATPase activity
C6W73_RS07235	COG2927	DNA polymerase III (CHI subunit)
C6W73_RS07240	COG0525	valine-tRNA ligase activity
C6W73_RS07245	COG4269	membrane
C6W73_RS07250	COG0456	acetyltransferase
C6W73_RS07255	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
C6W73_RS07275	COG2731	YhcH YjgK YiaL family protein
C6W73_RS07285	COG1028	Short-chain dehydrogenase reductase Sdr
C6W73_RS07290	COG0251	oxidation-reduction process
C6W73_RS07315	COG0251	oxidation-reduction process
C6W73_RS07325	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C6W73_RS07335	COG1609	Transcriptional regulator
C6W73_RS07340	COG1263	PTS System
C6W73_RS07340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6W73_RS07345	COG0366	Alpha amylase catalytic
C6W73_RS07350	COG1328	CTP reductase activity
C6W73_RS07355	COG0602	queuosine metabolic process
C6W73_RS07360	COG3783	Cytochrome b(562)
C6W73_RS07365	COG0312	modulator of DNA gyrase
C6W73_RS07375	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C6W73_RS07385	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6W73_RS07390	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6W73_RS07395	COG1129	ABC transporter
C6W73_RS07400	COG1879	ABC-type sugar transport system periplasmic component
C6W73_RS07405	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
C6W73_RS07410	COG2105	PFAM AIG2 family protein
C6W73_RS07415	COG2911	Protein conserved in bacteria
C6W73_RS07420	COG0729	surface antigen
C6W73_RS07435	COG1253	flavin adenine dinucleotide binding
C6W73_RS07445	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
C6W73_RS07450	COG1218	3'(2'),5'-bisphosphate nucleotidase
C6W73_RS07455	COG0737	Belongs to the 5'-nucleotidase family
C6W73_RS07460	COG1733	regulation of RNA biosynthetic process
C6W73_RS07465	COG0702	epimerase
C6W73_RS07470	COG0697	spore germination
C6W73_RS07480	COG1113	amino acid transport
C6W73_RS07485	COG0545	Peptidyl-prolyl cis-trans isomerase
C6W73_RS07490	COG3061	Opacity-associated protein A
C6W73_RS07495	COG1309	transcriptional regulator
C6W73_RS07510	COG1024	Enoyl-CoA hydratase
C6W73_RS07515	COG4670	ketone body catabolic process
C6W73_RS07520	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C6W73_RS07525	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
C6W73_RS07535	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C6W73_RS07545	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C6W73_RS07580	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6W73_RS07590	COG3037	sugar-specific permease SgaT UlaA
C6W73_RS07605	COG1073	alpha beta
C6W73_RS07610	COG3650	response to hydrogen peroxide
C6W73_RS07620	COG1960	acyl-CoA dehydrogenase activity
C6W73_RS07625	COG0754	glutathionylspermidine amidase activity
C6W73_RS07630	COG5463	Belongs to the UPF0441 family
C6W73_RS07635	COG3766	membrane
C6W73_RS07645	COG1842	Phage shock protein A
C6W73_RS07650	COG3789	protein conserved in bacteria
C6W73_RS07660	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C6W73_RS07665	COG0557	exoribonuclease II activity
C6W73_RS07680	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
C6W73_RS07685	COG0330	HflC and HflK could
C6W73_RS07690	COG0330	HflC and HflK could
C6W73_RS07695	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C6W73_RS07715	COG0860	N-Acetylmuramoyl-L-alanine amidase
C6W73_RS07720	COG0802	atpase or kinase
C6W73_RS07725	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C6W73_RS07725	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C6W73_RS07730	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C6W73_RS07770	COG3264	Mechanosensitive ion channel
C6W73_RS07770	COG1511	domain protein
C6W73_RS07775	COG0531	amino acid
C6W73_RS07785	COG1053	succinate dehydrogenase
C6W73_RS07790	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C6W73_RS07805	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C6W73_RS07810	COG3040	lipid binding
C6W73_RS07815	COG2076	Multidrug Resistance protein
C6W73_RS07820	COG5510	response to toxic substance
C6W73_RS07825	COG5510	response to toxic substance
C6W73_RS07835	COG1509	lysine 2,3-aminomutase activity
C6W73_RS07860	COG0531	amino acid
C6W73_RS07865	COG3030	protein affecting phage T7 exclusion by the F plasmid
C6W73_RS07870	COG1027	Aspartate ammonia-lyase
C6W73_RS07875	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C6W73_RS07890	COG1309	transcriptional regulator
C6W73_RS07900	COG0582	viral genome integration into host DNA
C6W73_RS07915	COG2194	sulfuric ester hydrolase activity
C6W73_RS07925	COG3852	Histidine kinase
C6W73_RS07930	COG2204	response regulator
C6W73_RS07935	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C6W73_RS07940	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C6W73_RS07945	COG2031	fatty acid transporter
C6W73_RS07950	COG0183	Belongs to the thiolase family
C6W73_RS08000	COG4771	TonB-dependent receptor
C6W73_RS08025	COG3119	arylsulfatase activity
C6W73_RS08050	COG2207	Transcriptional regulator
C6W73_RS08140	COG3210	domain, Protein
C6W73_RS08145	COG2994	toxin metabolic process
C6W73_RS08150	COG2831	hemolysin activation secretion protein
C6W73_RS08205	COG3436	PFAM IS66 Orf2 family protein
C6W73_RS08245	COG4983	Phage plasmid primase, P4 family domain protein
C6W73_RS08260	COG3468	outer membrane autotransporter barrel domain protein
C6W73_RS08305	COG2003	Belongs to the UPF0758 family
C6W73_RS08355	COG0531	amino acid
C6W73_RS08360	COG1982	Orn Lys Arg decarboxylase major
C6W73_RS08365	COG3104	oligopeptide transport
C6W73_RS08370	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C6W73_RS08390	COG2388	GCN5-related N-acetyl-transferase
C6W73_RS08395	COG3592	Divergent 4Fe-4S mono-cluster
C6W73_RS08400	COG3290	protein histidine kinase activity
C6W73_RS08405	COG4565	transcriptional regulatory protein
C6W73_RS08415	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C6W73_RS08420	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C6W73_RS08420	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C6W73_RS08425	COG3647	Membrane
C6W73_RS08430	COG2211	Major facilitator Superfamily
C6W73_RS08435	COG1486	melibiose metabolic process
C6W73_RS08445	COG2169	Transcriptional regulator
C6W73_RS08450	COG1982	Orn Lys Arg decarboxylase major
C6W73_RS08455	COG2207	Transcriptional regulator
C6W73_RS08460	COG0531	amino acid
C6W73_RS08465	COG2194	sulfuric ester hydrolase activity
C6W73_RS08470	COG0745	RESPONSE REGULATOR receiver
C6W73_RS08475	COG0642	Histidine kinase
C6W73_RS08485	COG0477	Major facilitator Superfamily
C6W73_RS08505	COG2824	Alkylphosphonate utilization operon protein PhnA
C6W73_RS08510	COG2764	glyoxalase bleomycin resistance protein dioxygenase
C6W73_RS08520	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
C6W73_RS08525	COG3639	organic phosphonate transmembrane transporter activity
C6W73_RS08530	COG2188	Transcriptional regulator
C6W73_RS08535	COG3624	Phosphonate C-P lyase system protein PhnG
C6W73_RS08545	COG3626	phosphonate metabolism
C6W73_RS08550	COG3627	carbon phosphorus lyase activity
C6W73_RS08555	COG4107	phosphonate C-P lyase system protein PhnK
C6W73_RS08560	COG4778	phosphonate C-P lyase system protein PhnL
C6W73_RS08565	COG3454	Phosphonate metabolism
C6W73_RS08570	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
C6W73_RS08575	COG0456	acetyltransferase
C6W73_RS08580	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C6W73_RS08590	COG0698	ribose 5-phosphate isomerase
C6W73_RS08595	COG2015	COG2015, Alkyl sulfatase and related hydrolases
C6W73_RS08605	COG1566	PFAM secretion protein HlyD family protein
C6W73_RS08610	COG1289	transmembrane transporter activity
C6W73_RS08625	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C6W73_RS08630	COG1301	dicarboxylic acid transport
C6W73_RS08640	COG4235	cytochrome complex assembly
C6W73_RS08645	COG3088	subunit of a heme lyase
C6W73_RS08650	COG1138	Cytochrome C-type biogenesis protein
C6W73_RS08655	COG3301	Polysulphide reductase, NrfD
C6W73_RS08660	COG0437	4 iron, 4 sulfur cluster binding
C6W73_RS08665	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
C6W73_RS08680	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C6W73_RS08685	COG3162	membrane
C6W73_RS08700	COG0025	NhaP-type Na H and K H
C6W73_RS08705	COG2252	PERMEase
C6W73_RS08725	COG0789	Transcriptional regulator
C6W73_RS08730	COG2207	Transcriptional regulator
C6W73_RS08735	COG4943	cyclic-guanylate-specific phosphodiesterase activity
C6W73_RS08750	COG0629	single-stranded DNA binding
C6W73_RS08755	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C6W73_RS08760	COG2315	Protein conserved in bacteria
C6W73_RS08765	COG0432	Pfam Uncharacterised protein family UPF0047
C6W73_RS08770	COG3700	Belongs to the class B bacterial acid phosphatase family
C6W73_RS08780	COG1448	Aminotransferase
C6W73_RS08785	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C6W73_RS08790	COG0305	Participates in initiation and elongation during chromosome replication
C6W73_RS08795	COG0604	alcohol dehydrogenase
C6W73_RS08805	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C6W73_RS08830	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6W73_RS08905	COG0740	serine-type endopeptidase activity
C6W73_RS08935	COG3772	lysozyme
C6W73_RS09020	COG1403	HNH endonuclease
C6W73_RS09030	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C6W73_RS09040	COG4725	Belongs to the MT-A70-like family
C6W73_RS09045	COG1846	Transcriptional regulator
C6W73_RS09055	COG3646	Phage regulatory protein
C6W73_RS09090	COG5532	Uncharacterized conserved protein (DUF2303)
C6W73_RS09095	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
C6W73_RS09145	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C6W73_RS09160	COG0735	belongs to the Fur family
C6W73_RS09165	COG3237	CsbD-like
C6W73_RS09170	COG0534	Mate efflux family protein
C6W73_RS09180	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C6W73_RS09205	COG1357	PFAM Pentapeptide repeats (8 copies)
C6W73_RS09225	COG3842	ATPase activity
C6W73_RS09235	COG2182	Extracellular solute-binding protein
C6W73_RS09240	COG1175	transmembrane transport
C6W73_RS09245	COG3833	ABC-type maltose transport systems, permease component
C6W73_RS09250	COG0477	Major facilitator Superfamily
C6W73_RS09250	COG2814	Major facilitator Superfamily
C6W73_RS09265	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C6W73_RS09295	COG0527	aspartate kinase activity
C6W73_RS09300	COG0542	response to heat
C6W73_RS09305	COG3541	Predicted nucleotidyltransferase
C6W73_RS09320	COG1187	pseudouridine synthase activity
C6W73_RS09335	COG0646	methionine synthase
C6W73_RS09335	COG1410	methionine synthase
C6W73_RS09340	COG1414	Transcriptional regulator
C6W73_RS09355	COG2224	Isocitrate lyase
C6W73_RS09360	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C6W73_RS09370	COG0456	acetyltransferase
C6W73_RS09405	COG0151	Belongs to the GarS family
C6W73_RS09410	COG2204	response regulator
C6W73_RS09415	COG4191	Histidine kinase
C6W73_RS09425	COG3678	ATP-independent chaperone mediated protein folding
C6W73_RS09440	COG3068	Protein conserved in bacteria
C6W73_RS09475	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C6W73_RS09480	COG2104	thiamine diphosphate biosynthetic process
C6W73_RS09490	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
C6W73_RS09530	COG0250	Participates in transcription elongation, termination and antitermination
C6W73_RS09535	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C6W73_RS09580	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
C6W73_RS09580	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
C6W73_RS09615	COG4206	TonB-dependent receptor
C6W73_RS09645	COG0583	DNA-binding transcription factor activity
C6W73_RS09650	COG2271	Major facilitator Superfamily
C6W73_RS09655	COG4948	Mandelate Racemase Muconate Lactonizing
C6W73_RS09675	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C6W73_RS09690	COG2194	sulfuric ester hydrolase activity
C6W73_RS09695	COG2207	Transcriptional regulator
C6W73_RS09700	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6W73_RS09705	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C6W73_RS09710	COG1882	Formate acetyltransferase
C6W73_RS09715	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6W73_RS09720	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6W73_RS09725	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C6W73_RS09725	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6W73_RS09725	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6W73_RS09730	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C6W73_RS09735	COG0371	Dehydrogenase
C6W73_RS09740	COG3738	Protein conserved in bacteria
C6W73_RS09745	COG0697	spore germination
C6W73_RS09755	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C6W73_RS09760	COG0527	aspartate kinase activity
C6W73_RS09760	COG0460	homoserine dehydrogenase
C6W73_RS09765	COG0626	cystathionine gamma-synthase activity
C6W73_RS09775	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
C6W73_RS09790	COG3209	COG3209 Rhs family protein
C6W73_RS09800	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C6W73_RS09805	COG1609	Transcriptional regulator
C6W73_RS09810	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C6W73_RS09825	COG1575	Belongs to the MenA family. Type 1 subfamily
C6W73_RS09840	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C6W73_RS09850	COG1494	fructose-1,6-bisphosphatase
C6W73_RS09860	COG0589	response to stress
C6W73_RS09865	COG3691	Protein conserved in bacteria
C6W73_RS09870	COG3152	Membrane
C6W73_RS09890	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C6W73_RS09905	COG3678	ATP-independent chaperone mediated protein folding
C6W73_RS09910	COG0745	RESPONSE REGULATOR receiver
C6W73_RS09915	COG2205	protein histidine kinase activity
C6W73_RS09920	COG2258	MOSC domain
C6W73_RS09935	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C6W73_RS09975	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6W73_RS09980	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6W73_RS09980	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6W73_RS09985	COG1363	Peptidase, m42
C6W73_RS09990	COG3711	transcriptional antiterminator
C6W73_RS09990	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6W73_RS10010	COG0243	molybdopterin cofactor binding
C6W73_RS10010	COG3383	formate dehydrogenase (NAD+) activity
C6W73_RS10015	COG3383	formate dehydrogenase (NAD+) activity
C6W73_RS10015	COG0243	molybdopterin cofactor binding
C6W73_RS10020	COG0437	4 iron, 4 sulfur cluster binding
C6W73_RS10025	COG2864	formate dehydrogenase
C6W73_RS10035	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C6W73_RS10040	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C6W73_RS10055	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
C6W73_RS10065	COG0456	acetyltransferase
C6W73_RS10080	COG1011	Hydrolase
C6W73_RS10085	COG1349	DNA-binding transcription factor activity
C6W73_RS10090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6W73_RS10095	COG2084	Dehydrogenase
C6W73_RS10100	COG3684	Belongs to the aldolase LacD family
C6W73_RS10105	COG2942	2-epimerase
C6W73_RS10110	COG2017	converts alpha-aldose to the beta-anomer
C6W73_RS10115	COG1501	Belongs to the glycosyl hydrolase 31 family
C6W73_RS10120	COG2211	Major facilitator Superfamily
C6W73_RS10125	COG2211	Major facilitator Superfamily
C6W73_RS10130	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
C6W73_RS10135	COG2271	Major facilitator Superfamily
C6W73_RS10140	COG1082	Xylose isomerase domain protein TIM barrel
C6W73_RS10145	COG2188	Transcriptional regulator
C6W73_RS10150	COG1217	gtp-binding protein TYPA
C6W73_RS10160	COG0174	glutamine synthetase
C6W73_RS10170	COG3852	Histidine kinase
C6W73_RS10175	COG2204	response regulator
C6W73_RS10185	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C6W73_RS10200	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C6W73_RS10200	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C6W73_RS10210	COG0204	Acyl-transferase
C6W73_RS10215	COG5339	Protein conserved in bacteria
C6W73_RS10220	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C6W73_RS10225	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C6W73_RS10230	COG3084	Protein conserved in bacteria
C6W73_RS10235	COG0746	molybdenum cofactor guanylyltransferase activity
C6W73_RS10240	COG1763	Mo-molybdopterin cofactor biosynthetic process
C6W73_RS10270	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
C6W73_RS10275	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C6W73_RS10280	COG1739	Uncharacterized protein family UPF0029
C6W73_RS10300	COG0543	2 iron, 2 sulfur cluster binding
C6W73_RS10305	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C6W73_RS10310	COG0250	Participates in transcription elongation, termination and antitermination
C6W73_RS10320	COG0805	protein transport
C6W73_RS10325	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C6W73_RS10330	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C6W73_RS10340	COG3165	ubiquinone biosynthetic process from chorismate
C6W73_RS10350	COG1322	Protein conserved in bacteria
C6W73_RS10355	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
C6W73_RS10360	COG0412	Dienelactone hydrolase
C6W73_RS10370	COG0583	DNA-binding transcription factor activity
C6W73_RS10375	COG0697	spore germination
C6W73_RS10380	COG0561	phosphatase activity
C6W73_RS10385	COG2267	carboxylic ester hydrolase activity
C6W73_RS10390	COG1280	lysine exporter protein (LysE YggA)
C6W73_RS10395	COG1280	lysine exporter protein (LysE YggA)
C6W73_RS10400	COG0514	ATP-dependent DNA helicase (RecQ)
C6W73_RS10405	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
C6W73_RS10410	COG2050	protein possibly involved in aromatic compounds catabolism
C6W73_RS10415	COG2962	Rard protein
C6W73_RS10445	COG0598	Magnesium transport protein CorA
C6W73_RS10450	COG3698	Phosphodiester glycosidase
C6W73_RS10455	COG0210	DNA helicase
C6W73_RS10460	COG1011	Hydrolase
C6W73_RS10470	COG3159	Protein conserved in bacteria
C6W73_RS10480	COG5567	small periplasmic lipoprotein
C6W73_RS10495	COG3072	Adenylate cyclase
C6W73_RS10510	COG1587	Uroporphyrinogen-III synthase
C6W73_RS10515	COG2959	enzyme of heme biosynthesis
C6W73_RS10520	COG3071	HemY protein
C6W73_RS10525	COG0641	radical SAM
C6W73_RS10550	COG1113	amino acid transport
C6W73_RS10570	COG2244	polysaccharide biosynthetic process
C6W73_RS10575	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C6W73_RS10580	COG0456	acetyltransferase
C6W73_RS10585	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C6W73_RS10590	COG1088	dTDP-glucose 4,6-dehydratase activity
C6W73_RS10595	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
C6W73_RS10600	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C6W73_RS10605	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
C6W73_RS10610	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C6W73_RS10620	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C6W73_RS10630	COG3118	belongs to the thioredoxin family
C6W73_RS10650	COG0210	DNA helicase
C6W73_RS10655	COG3692	DNA binding
C6W73_RS10660	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C6W73_RS10670	COG0583	DNA-binding transcription factor activity
C6W73_RS10675	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C6W73_RS10685	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C6W73_RS10690	COG3978	acetolactate synthase activity
C6W73_RS10715	COG0606	chelatase, subunit chli
C6W73_RS10720	COG3085	chromosome segregation
C6W73_RS10760	COG2186	Transcriptional regulator
C6W73_RS10765	COG0477	Major facilitator Superfamily
C6W73_RS10770	COG1609	Transcriptional regulator
C6W73_RS10775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6W73_RS10780	COG1879	ABC-type sugar transport system periplasmic component
C6W73_RS10785	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6W73_RS10790	COG1129	ABC transporter
C6W73_RS10820	COG1522	sequence-specific DNA binding
C6W73_RS10825	COG0716	FMN binding
C6W73_RS10840	COG3312	ion transport
C6W73_RS10895	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C6W73_RS10910	COG3188	usher protein
C6W73_RS10920	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C6W73_RS10925	COG0573	inorganic phosphate transmembrane transporter activity
C6W73_RS10930	COG0581	inorganic phosphate transmembrane transporter activity
C6W73_RS10935	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C6W73_RS10940	COG0704	Plays a role in the regulation of phosphate uptake
C6W73_RS10945	COG3711	transcriptional antiterminator
C6W73_RS10950	COG1263	PTS System
C6W73_RS10950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6W73_RS10950	COG2190	(PTS) system
C6W73_RS10955	COG2723	6-phospho-beta-galactosidase activity
C6W73_RS10965	COG2382	esterase
C6W73_RS10970	COG0363	glucosamine-6-phosphate deaminase activity
C6W73_RS10980	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C6W73_RS10985	COG2252	PERMEase
C6W73_RS10990	COG0431	NADPH-dependent FMN reductase
C6W73_RS10995	COG2091	lysine biosynthetic process via aminoadipic acid
C6W73_RS11010	COG0814	amino acid
C6W73_RS11060	COG0592	DNA-directed DNA polymerase activity
C6W73_RS11070	COG0187	DNA topoisomerase II activity
C6W73_RS11075	COG3753	Protein conserved in bacteria
C6W73_RS11080	COG0561	phosphatase activity
C6W73_RS11090	COG2186	Transcriptional regulator
C6W73_RS11095	COG3734	2-keto-3-deoxy-galactonokinase
C6W73_RS11100	COG0800	Aldolase
C6W73_RS11110	COG2271	Major facilitator Superfamily
C6W73_RS11120	COG0823	Involved in the tonB-independent uptake of proteins
C6W73_RS11125	COG5645	(Lipo)protein
C6W73_RS11145	COG2188	Transcriptional regulator
C6W73_RS11165	COG2207	Transcriptional regulator
C6W73_RS11170	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C6W73_RS11175	COG3119	arylsulfatase activity
C6W73_RS11185	COG2149	membrane
C6W73_RS11195	COG0641	radical SAM
C6W73_RS11200	COG2814	Major facilitator Superfamily
C6W73_RS11235	COG0028	Belongs to the TPP enzyme family
C6W73_RS11240	COG0440	acetolactate synthase activity
C6W73_RS11245	COG2197	response regulator
C6W73_RS11250	COG3851	Histidine kinase
C6W73_RS11255	COG2271	Major facilitator Superfamily
C6W73_RS11260	COG2271	Major facilitator Superfamily
C6W73_RS11270	COG2252	PERMEase
C6W73_RS11300	COG1464	Belongs to the NlpA lipoprotein family
C6W73_RS11305	COG0697	spore germination
C6W73_RS11310	COG2814	Major facilitator Superfamily
C6W73_RS11325	COG2211	Major facilitator Superfamily
C6W73_RS11330	COG1501	Belongs to the glycosyl hydrolase 31 family
C6W73_RS11335	COG2982	Protein involved in outer membrane biogenesis
C6W73_RS11340	COG2233	PERMEase
C6W73_RS11345	COG0786	glutamate:sodium symporter activity
C6W73_RS11355	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C6W73_RS11360	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C6W73_RS11365	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C6W73_RS11375	COG0194	GDP metabolic process
C6W73_RS11385	COG2860	membrane
C6W73_RS11390	COG3645	SOS response
C6W73_RS11395	COG1561	YicC-like family, N-terminal region
C6W73_RS11425	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C6W73_RS11455	COG1519	Transferase
C6W73_RS11460	COG0859	PFAM glycosyl transferase family 9
C6W73_RS11465	COG0438	transferase activity, transferring glycosyl groups
C6W73_RS11470	COG0515	serine threonine protein kinase
C6W73_RS11485	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C6W73_RS11490	COG1442	glycosyl transferase family 8
C6W73_RS11495	COG1216	Glycosyl transferase, family 2
C6W73_RS11500	COG3307	-O-antigen
C6W73_RS11505	COG0859	PFAM glycosyl transferase family 9
C6W73_RS11510	COG0859	PFAM glycosyl transferase family 9
C6W73_RS11520	COG0156	8-amino-7-oxononanoate synthase activity
C6W73_RS11530	COG1216	Glycosyl transferase, family 2
C6W73_RS11535	COG2861	carbohydrate metabolic process
C6W73_RS11540	COG4942	peptidase
C6W73_RS11555	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C6W73_RS11560	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C6W73_RS11575	COG1045	serine acetyltransferase
C6W73_RS11580	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C6W73_RS11590	COG2186	Transcriptional regulator
C6W73_RS11595	COG1620	l-lactate permease
C6W73_RS11600	COG5295	Hep Hag repeat protein
C6W73_RS11625	COG3722	fumarate hydratase activity
C6W73_RS11635	COG2213	PTS system mannitol-specific
C6W73_RS11635	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6W73_RS11645	COG1566	PFAM secretion protein HlyD family protein
C6W73_RS11665	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C6W73_RS11675	COG1413	lyase activity
C6W73_RS11685	COG3209	COG3209 Rhs family protein
C6W73_RS11690	COG0625	glutathione transferase activity
C6W73_RS11700	COG3276	selenocysteine insertion sequence binding
C6W73_RS11705	COG1454	alcohol dehydrogenase
C6W73_RS11710	COG1012	belongs to the aldehyde dehydrogenase family
C6W73_RS11725	COG1566	PFAM secretion protein HlyD family protein
C6W73_RS11730	COG0583	DNA-binding transcription factor activity
C6W73_RS11735	COG3713	MltA-interacting MipA family protein
C6W73_RS11745	COG2211	Major facilitator Superfamily
C6W73_RS11755	COG0235	Class ii aldolase
C6W73_RS11760	COG3623	hexulose-6-phosphate isomerase
C6W73_RS11765	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
C6W73_RS11770	COG1070	Carbohydrate kinase
C6W73_RS11775	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C6W73_RS11780	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
C6W73_RS11785	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
C6W73_RS11790	COG2731	YhcH YjgK YiaL family protein
C6W73_RS11800	COG1414	Transcriptional regulator
C6W73_RS11805	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6W73_RS11810	COG3977	Valine--pyruvate aminotransferase
C6W73_RS11815	COG0366	Alpha amylase catalytic
C6W73_RS11820	COG2992	FlgJ-related protein
C6W73_RS11825	COG1609	Transcriptional regulator
C6W73_RS11825	COG2207	Transcriptional regulator
C6W73_RS11830	COG4214	carbohydrate transport
C6W73_RS11835	COG1129	ABC transporter
C6W73_RS11840	COG4213	ABC transporter substrate-binding protein
C6W73_RS11850	COG1070	Carbohydrate kinase
C6W73_RS11855	COG4682	membrane
C6W73_RS11860	COG4682	membrane
C6W73_RS11865	COG3274	enterobacterial common antigen metabolic process
C6W73_RS11890	COG1278	Cold shock
C6W73_RS11895	COG2944	sequence-specific DNA binding
C6W73_RS11910	COG2885	chlorophyll binding
C6W73_RS11915	COG0243	molybdopterin cofactor binding
C6W73_RS11920	COG0456	acetyltransferase
C6W73_RS11925	COG2818	Glycosylase
C6W73_RS11930	COG5571	outer membrane autotransporter
C6W73_RS11940	COG2223	nitrite transmembrane transporter activity
C6W73_RS11945	COG2194	sulfuric ester hydrolase activity
C6W73_RS11965	COG3547	Transposase (IS116 IS110 IS902 family)
C6W73_RS11975	COG0747	negative chemotaxis
C6W73_RS11980	COG0601	transmembrane transport
C6W73_RS11985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C6W73_RS11990	COG0444	Belongs to the ABC transporter superfamily
C6W73_RS11995	COG4608	Belongs to the ABC transporter superfamily
C6W73_RS12000	COG0814	amino acid
C6W73_RS12030	COG2194	sulfuric ester hydrolase activity
C6W73_RS12055	COG1215	transferase activity, transferring glycosyl groups
C6W73_RS12060	COG1215	transferase activity, transferring glycosyl groups
C6W73_RS12065	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
C6W73_RS12070	COG0457	Tetratricopeptide repeat
C6W73_RS12070	COG3118	belongs to the thioredoxin family
C6W73_RS12075	COG2200	EAL domain
C6W73_RS12075	COG2199	diguanylate cyclase activity
C6W73_RS12090	COG0612	Peptidase, M16
C6W73_RS12105	COG2200	EAL domain
C6W73_RS12110	COG2982	Protein involved in outer membrane biogenesis
C6W73_RS12115	COG0477	Major facilitator Superfamily
C6W73_RS12120	COG1295	ribonuclease BN
C6W73_RS12125	COG0583	DNA-binding transcription factor activity
C6W73_RS12130	COG2197	response regulator
C6W73_RS12140	COG1858	cytochrome C peroxidase
C6W73_RS12145	COG0076	glutamate decarboxylase activity
C6W73_RS12155	COG2207	Transcriptional regulator
C6W73_RS12165	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C6W73_RS12170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6W73_RS12180	COG2771	luxR family
C6W73_RS12185	COG3247	response to pH
C6W73_RS12200	COG1285	pathogenesis
C6W73_RS12205	COG2197	response regulator
C6W73_RS12215	COG3065	identical protein binding
C6W73_RS12240	COG1393	Belongs to the ArsC family
C6W73_RS12245	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C6W73_RS12250	COG0640	Transcriptional regulator
C6W73_RS12265	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C6W73_RS12270	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
C6W73_RS12275	COG0339	signal peptide processing
C6W73_RS12285	COG3104	oligopeptide transport
C6W73_RS12295	COG0589	response to stress
C6W73_RS12305	COG0306	phosphate transporter
C6W73_RS12310	COG2081	HI0933 family
C6W73_RS12335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6W73_RS12340	COG1129	ABC transporter
C6W73_RS12340	COG0842	Transport permease protein
C6W73_RS12345	COG0842	Transport permease protein
C6W73_RS12360	COG0191	fructose-bisphosphate aldolase activity
C6W73_RS12375	COG3775	system Galactitol-specific IIC component
C6W73_RS12380	COG3414	Phosphotransferase system galactitol-specific IIB component
C6W73_RS12390	COG2188	Transcriptional regulator
C6W73_RS12405	COG0444	Belongs to the ABC transporter superfamily
C6W73_RS12410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C6W73_RS12415	COG0601	transmembrane transport
C6W73_RS12420	COG0747	negative chemotaxis
C6W73_RS12425	COG2091	lysine biosynthetic process via aminoadipic acid
C6W73_RS12430	COG0628	permease
C6W73_RS12445	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C6W73_RS12460	COG3714	YhhN family
C6W73_RS12470	COG3776	membrane
C6W73_RS12475	COG0742	ribosomal rna small subunit methyltransferase
C6W73_RS12480	COG0552	protein localization to endoplasmic reticulum
C6W73_RS12485	COG2884	Cell division ATP-binding protein ftsE
C6W73_RS12490	COG2177	Part of the ABC transporter FtsEX involved in
C6W73_RS12495	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C6W73_RS12500	COG0683	leucine binding
C6W73_RS12505	COG0456	acetyltransferase
C6W73_RS12510	COG0683	leucine binding
C6W73_RS12515	COG0559	Belongs to the binding-protein-dependent transport system permease family
C6W73_RS12520	COG4177	L-phenylalanine transmembrane transporter activity
C6W73_RS12525	COG0411	ABC transporter
C6W73_RS12530	COG0410	ABC transporter
C6W73_RS12535	COG1653	transport
C6W73_RS12540	COG1175	transmembrane transport
C6W73_RS12550	COG3842	ATPase activity
C6W73_RS12555	COG0584	glycerophosphoryl diester phosphodiesterase
C6W73_RS12565	COG0405	Gamma-glutamyltransferase
C6W73_RS12585	COG3157	Type VI secretion system effector, Hcp
C6W73_RS12590	COG1247	-acetyltransferase
C6W73_RS12600	COG0673	inositol 2-dehydrogenase activity
C6W73_RS12605	COG1741	Belongs to the pirin family
C6W73_RS12610	COG1609	Transcriptional regulator
C6W73_RS12615	COG3265	gluconokinase activity
C6W73_RS12620	COG2610	gluconate transmembrane transporter activity
C6W73_RS12625	COG2095	MarC family integral membrane protein
C6W73_RS12630	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C6W73_RS12655	COG0058	SHG alpha-glucan phosphorylase activity
C6W73_RS12665	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C6W73_RS12685	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C6W73_RS12700	COG1349	DNA-binding transcription factor activity
C6W73_RS12705	COG4650	regulator
C6W73_RS12710	COG1690	Belongs to the RtcB family
C6W73_RS12725	COG0058	SHG alpha-glucan phosphorylase activity
C6W73_RS12730	COG1640	4-alpha-glucanotransferase
C6W73_RS12735	COG2610	gluconate transmembrane transporter activity
C6W73_RS12755	COG5464	transposase or invertase
C6W73_RS12770	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
C6W73_RS12775	COG1918	ferrous iron import across plasma membrane
C6W73_RS12785	COG2183	response to ionizing radiation
C6W73_RS12790	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C6W73_RS12830	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
C6W73_RS12840	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C6W73_RS12845	COG1011	Hydrolase
C6W73_RS12855	COG0494	nUDIX hydrolase
C6W73_RS12860	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
C6W73_RS12865	COG4972	Pilus assembly protein
C6W73_RS12870	COG3166	PFAM Fimbrial assembly family protein
C6W73_RS12885	COG4796	Type ii and iii secretion system protein
C6W73_RS12905	COG3266	domain, Protein
C6W73_RS12910	COG0338	D12 class N6 adenine-specific DNA methyltransferase
C6W73_RS12915	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C6W73_RS12920	COG0546	phosphoglycolate phosphatase activity
C6W73_RS12925	COG0180	Tryptophanyl-tRNA synthetase
C6W73_RS12930	COG2188	Transcriptional regulator
C6W73_RS12940	COG3457	Alanine racemase
C6W73_RS12945	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
C6W73_RS12965	COG0626	cystathionine gamma-synthase activity
C6W73_RS12970	COG2188	Transcriptional regulator
C6W73_RS12975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6W73_RS12980	COG1082	Xylose isomerase domain protein TIM barrel
C6W73_RS12990	COG2222	sugar isomerase
C6W73_RS12995	COG0531	amino acid
C6W73_RS13010	COG2116	formate transmembrane transporter activity
C6W73_RS13015	COG2146	nitrite reductase [NAD(P)H] activity
C6W73_RS13020	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C6W73_RS13030	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C6W73_RS13040	COG2184	nucleotidyltransferase activity
C6W73_RS13045	COG0512	Glutamine amidotransferase of anthranilate synthase
C6W73_RS13050	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C6W73_RS13055	COG1289	transmembrane transporter activity
C6W73_RS13060	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C6W73_RS13070	COG1765	OsmC-like protein
C6W73_RS13075	COG3954	Phosphoribulokinase
C6W73_RS13085	COG0429	hydrolase of the alpha beta-hydrolase fold
C6W73_RS13090	COG0488	(ABC) transporter
C6W73_RS13110	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
C6W73_RS13115	COG1047	Peptidyl-prolyl cis-trans
C6W73_RS13125	COG0545	Peptidyl-prolyl cis-trans isomerase
C6W73_RS13130	COG2964	Protein conserved in bacteria
C6W73_RS13210	COG0089	rRNA binding
C6W73_RS13300	COG0201	protein transport
C6W73_RS13340	COG0789	Transcriptional regulator
C6W73_RS13345	COG3036	rescue of stalled ribosome
C6W73_RS13355	COG0569	domain protein
C6W73_RS13375	COG0758	DNA mediated transformation
C6W73_RS13385	COG0551	DNA topoisomerase type I activity
C6W73_RS13405	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C6W73_RS13445	COG1126	abc transporter atp-binding protein
C6W73_RS13450	COG0765	amino acid transport
C6W73_RS13455	COG4597	amino acid ABC transporter
C6W73_RS13460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6W73_RS13475	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C6W73_RS13480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6W73_RS13490	COG1309	transcriptional regulator
C6W73_RS13500	COG2189	Belongs to the N(4) N(6)-methyltransferase family
C6W73_RS13510	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C6W73_RS13520	COG4145	pantothenate transmembrane transporter activity
C6W73_RS13525	COG3924	membrane
C6W73_RS13530	COG0439	Biotin carboxylase
C6W73_RS13535	COG0511	ligase activity, forming carbon-carbon bonds
C6W73_RS13545	COG0604	alcohol dehydrogenase
C6W73_RS13550	COG2199	diguanylate cyclase activity
C6W73_RS13550	COG2200	EAL domain
C6W73_RS13565	COG1077	Cell shape determining protein MreB Mrl
C6W73_RS13570	COG1792	Involved in formation and maintenance of cell shape
C6W73_RS13575	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C6W73_RS13585	COG1530	ribonuclease E activity
C6W73_RS13590	COG3164	Protein of unknown function
C6W73_RS13595	COG0312	modulator of DNA gyrase
C6W73_RS13600	COG0583	DNA-binding transcription factor activity
C6W73_RS13620	COG2732	(Barnase) inhibitor
C6W73_RS13640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C6W73_RS13645	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C6W73_RS13650	COG3105	Protein conserved in bacteria
C6W73_RS13655	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
C6W73_RS13685	COG0625	glutathione transferase activity
C6W73_RS13690	COG2969	positive regulation of protein catabolic process
C6W73_RS13695	COG3069	C4-dicarboxylate transmembrane transporter activity
C6W73_RS13730	COG2731	YhcH YjgK YiaL family protein
C6W73_RS13740	COG4804	nuclease activity
C6W73_RS13745	COG0493	'glutamate synthase
C6W73_RS13750	COG0070	glutamate synthase
C6W73_RS13750	COG0069	glutamate synthase activity
C6W73_RS13750	COG0067	glutamate synthase
C6W73_RS13765	COG1242	4 iron, 4 sulfur cluster binding
C6W73_RS13770	COG2198	Histidine kinase
C6W73_RS13770	COG5002	protein histidine kinase activity
C6W73_RS13770	COG0784	Response regulator, receiver
C6W73_RS13775	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
C6W73_RS13785	COG0515	serine threonine protein kinase
C6W73_RS13790	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6W73_RS13805	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C6W73_RS13810	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C6W73_RS13815	COG1137	ATPase activity
C6W73_RS13820	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
C6W73_RS13825	COG3117	lipopolysaccharide transmembrane transporter activity
C6W73_RS13830	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
C6W73_RS13835	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C6W73_RS13835	COG0517	IMP dehydrogenase activity
C6W73_RS13840	COG0530	calcium, potassium:sodium antiporter activity
C6W73_RS13845	COG1127	ABC transporter
C6W73_RS13850	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C6W73_RS13855	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C6W73_RS13860	COG2854	intermembrane phospholipid transfer
C6W73_RS13865	COG3113	response to antibiotic
C6W73_RS13870	COG5007	Belongs to the BolA IbaG family
C6W73_RS13880	COG3423	Transcriptional regulator
C6W73_RS13885	COG0142	geranyltranstransferase activity
C6W73_RS13900	COG0697	spore germination
C6W73_RS13910	COG2027	D-alanyl-D-alanine carboxypeptidase
C6W73_RS13915	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C6W73_RS13920	COG1534	Rna-binding protein
C6W73_RS13930	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C6W73_RS13935	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C6W73_RS13945	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C6W73_RS13955	COG2194	sulfuric ester hydrolase activity
C6W73_RS13975	COG0195	Participates in both transcription termination and antitermination
C6W73_RS14015	COG0513	Belongs to the DEAD box helicase family
C6W73_RS14020	COG0814	amino acid
C6W73_RS14030	COG3547	Transposase (IS116 IS110 IS902 family)
C6W73_RS14035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C6W73_RS14040	COG0826	peptidase U32
C6W73_RS14045	COG0826	peptidase U32
C6W73_RS14050	COG3154	lipid carrier protein
C6W73_RS14055	COG3153	acetyltransferase
C6W73_RS14070	COG0693	protein deglycase activity
C6W73_RS14075	COG0702	epimerase
C6W73_RS14080	COG0701	Predicted permease
C6W73_RS14085	COG2823	Periplasmic or secreted lipoprotein
C6W73_RS14105	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C6W73_RS14110	COG3539	Fimbrial protein
C6W73_RS14115	COG3188	usher protein
C6W73_RS14120	COG3121	Chaperone
C6W73_RS14125	COG3539	Fimbrial protein
C6W73_RS14130	COG0363	glucosamine-6-phosphate deaminase activity
C6W73_RS14135	COG3716	PTS system mannose fructose sorbose family IID component
C6W73_RS14140	COG3715	PTS system
C6W73_RS14145	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6W73_RS14155	COG2222	sugar isomerase
C6W73_RS14160	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C6W73_RS14165	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6W73_RS14170	COG3716	PTS system mannose fructose sorbose family IID component
C6W73_RS14180	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6W73_RS14195	COG1349	DNA-binding transcription factor activity
C6W73_RS14205	COG2002	toxin-antitoxin pair type II binding
C6W73_RS14210	COG2721	sulfolactate sulfo-lyase activity
C6W73_RS14215	COG2271	Major facilitator Superfamily
C6W73_RS14225	COG2084	Dehydrogenase
C6W73_RS14230	COG1929	Belongs to the glycerate kinase type-1 family
C6W73_RS14255	COG0583	DNA-binding transcription factor activity
C6W73_RS14265	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C6W73_RS14275	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C6W73_RS14280	COG1882	Formate acetyltransferase
C6W73_RS14285	COG0251	oxidation-reduction process
C6W73_RS14290	COG1760	l-serine dehydratase
C6W73_RS14300	COG0814	amino acid
C6W73_RS14315	COG1741	Belongs to the pirin family
C6W73_RS14320	COG0583	DNA-binding transcription factor activity
C6W73_RS14330	COG3152	Membrane
C6W73_RS14335	COG3152	Membrane
C6W73_RS14340	COG0435	Glutathione S-transferase
C6W73_RS14345	COG2259	Doxx family
C6W73_RS14355	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
C6W73_RS14360	COG4575	ribosome binding
C6W73_RS14365	COG1422	Protein of unknown function (DUF1090)
C6W73_RS14375	COG0586	Pfam SNARE associated Golgi protein
C6W73_RS14380	COG2186	Transcriptional regulator
C6W73_RS14410	COG2271	Major facilitator Superfamily
C6W73_RS14420	COG2721	sulfolactate sulfo-lyase activity
C6W73_RS14430	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
C6W73_RS14435	COG0861	Integral membrane protein TerC family
C6W73_RS14440	COG0673	inositol 2-dehydrogenase activity
C6W73_RS14445	COG2949	membrane
C6W73_RS14450	COG1451	nucleotide metabolic process
C6W73_RS14460	COG4680	protein conserved in bacteria
C6W73_RS14465	COG5499	transcription regulator containing HTH domain
C6W73_RS14470	COG1902	pentaerythritol trinitrate reductase activity
C6W73_RS14470	COG0446	pyridine nucleotide-disulphide oxidoreductase
C6W73_RS14475	COG3408	Glycogen debranching enzyme
C6W73_RS14475	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
C6W73_RS14485	COG0531	amino acid
C6W73_RS14490	COG2731	YhcH YjgK YiaL family protein
C6W73_RS14495	COG3250	beta-galactosidase activity
C6W73_RS14500	COG1609	Transcriptional regulator
C6W73_RS14510	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C6W73_RS14525	COG0840	transmembrane signaling receptor activity
C6W73_RS14530	COG1695	Transcriptional regulator
C6W73_RS14540	COG2375	cellular response to nickel ion
C6W73_RS14555	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C6W73_RS14565	COG0358	DNA primase activity
C6W73_RS14570	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C6W73_RS14580	COG0471	metal ion transport
C6W73_RS14585	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C6W73_RS14590	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C6W73_RS14600	COG0583	DNA-binding transcription factor activity
C6W73_RS14610	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C6W73_RS14625	COG4991	sh3 domain protein
C6W73_RS14635	COG3025	triphosphatase activity
C6W73_RS14665	COG2268	Band 7 protein
C6W73_RS14670	COG1585	Membrane protein implicated in regulation of membrane protease activity
C6W73_RS14680	COG3539	Fimbrial protein
C6W73_RS14690	COG3188	usher protein
C6W73_RS14695	COG3539	Fimbrial protein
C6W73_RS14700	COG2960	long-chain fatty acid transporting porin activity
C6W73_RS14720	COG3384	dioxygenase
C6W73_RS14725	COG0754	glutathionylspermidine amidase activity
C6W73_RS14740	COG1538	Outer membrane efflux protein
C6W73_RS14745	COG0494	nUDIX hydrolase
C6W73_RS14750	COG3151	Protein conserved in bacteria
C6W73_RS14755	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C6W73_RS14760	COG3150	esterase
C6W73_RS14765	COG0187	DNA topoisomerase II activity
C6W73_RS14770	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C6W73_RS14775	COG2249	NAD(P)H dehydrogenase (quinone) activity
C6W73_RS14785	COG0642	Histidine kinase
C6W73_RS14790	COG0745	RESPONSE REGULATOR receiver
C6W73_RS14795	COG3111	PFAM Bacterial OB fold (BOF) protein
C6W73_RS14800	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
C6W73_RS14810	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C6W73_RS14815	COG0204	Acyl-transferase
C6W73_RS14820	COG2132	Multicopper oxidase
C6W73_RS14825	COG1032	radical SAM domain protein
C6W73_RS14830	COG4238	major outer membrane lipoprotein
C6W73_RS14840	COG0656	L-ascorbic acid biosynthetic process
C6W73_RS14845	COG1979	alcohol dehydrogenase
C6W73_RS14850	COG2207	Transcriptional regulator
C6W73_RS14855	COG0586	Pfam SNARE associated Golgi protein
C6W73_RS14860	COG0626	cystathionine gamma-synthase activity
C6W73_RS14870	COG0811	peptide transport
C6W73_RS14875	COG0848	biopolymer transport protein
C6W73_RS14880	COG1028	Short-chain dehydrogenase reductase Sdr
C6W73_RS14890	COG0667	Aldo Keto reductase
C6W73_RS14910	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
C6W73_RS14915	COG0437	4 iron, 4 sulfur cluster binding
C6W73_RS14920	COG5557	Pfam Polysulphide reductase, NrfD
C6W73_RS14925	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
C6W73_RS14930	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C6W73_RS14935	COG1773	rubredoxin
C6W73_RS14945	COG0298	carbon dioxide binding
C6W73_RS14950	COG0625	glutathione transferase activity
C6W73_RS14955	COG0754	glutathionylspermidine amidase activity
C6W73_RS14960	COG0306	phosphate transporter
C6W73_RS14965	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C6W73_RS14970	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C6W73_RS14975	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C6W73_RS14980	COG2244	polysaccharide biosynthetic process
C6W73_RS14990	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
C6W73_RS14995	COG0795	lipopolysaccharide-transporting ATPase activity
C6W73_RS15005	COG0156	8-amino-7-oxononanoate synthase activity
C6W73_RS15010	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C6W73_RS15020	COG0318	PFAM AMP-dependent synthetase and ligase
C6W73_RS15030	COG0456	acetyltransferase
C6W73_RS15035	COG2186	Transcriptional regulator
C6W73_RS15040	COG0277	FAD linked oxidase domain protein
C6W73_RS15045	COG0277	FAD linked oxidase domain protein
C6W73_RS15050	COG0247	lactate metabolic process
C6W73_RS15055	COG3193	protein, possibly involved in utilization of glycolate and propanediol
C6W73_RS15060	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C6W73_RS15065	COG1620	l-lactate permease
C6W73_RS15100	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C6W73_RS15105	COG1459	type II secretion system
C6W73_RS15110	COG2165	general secretion pathway protein
C6W73_RS15140	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
C6W73_RS15175	COG2003	Belongs to the UPF0758 family
C6W73_RS15205	COG2020	methyltransferase activity
C6W73_RS15210	COG3468	outer membrane autotransporter barrel domain protein
C6W73_RS15225	COG4983	Phage plasmid primase, P4 family domain protein
C6W73_RS15285	COG3436	PFAM IS66 Orf2 family protein
C6W73_RS15290	COG4372	Transposase
C6W73_RS15330	COG2831	hemolysin activation secretion protein
C6W73_RS15335	COG2994	toxin metabolic process
C6W73_RS15340	COG3210	domain, Protein
C6W73_RS15370	COG3210	domain, Protein
C6W73_RS15405	COG3969	phosphoadenosine phosphosulfate
C6W73_RS15410	COG1475	DNA binding
C6W73_RS15430	COG1201	RNA secondary structure unwinding
C6W73_RS15455	COG2194	sulfuric ester hydrolase activity
C6W73_RS15460	COG0582	viral genome integration into host DNA
C6W73_RS15470	COG1811	Na channel or pump
C6W73_RS15480	COG1982	Orn Lys Arg decarboxylase major
C6W73_RS15485	COG2211	Major facilitator Superfamily
C6W73_RS15500	COG1194	a g-specific adenine glycosylase
C6W73_RS15515	COG3171	Protein conserved in bacteria
C6W73_RS15525	COG0252	asparaginase activity
C6W73_RS15540	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
C6W73_RS15545	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C6W73_RS15550	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C6W73_RS15565	COG0762	integral membrane protein
C6W73_RS15570	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C6W73_RS15575	COG2805	Type II/IV secretion system protein
C6W73_RS15590	COG0189	ligase activity
C6W73_RS15595	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C6W73_RS15600	COG2356	endonuclease I
C6W73_RS15610	COG2814	Major facilitator Superfamily
C6W73_RS15635	COG1166	arginine decarboxylase activity
C6W73_RS15660	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6W73_RS15660	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6W73_RS15665	COG3715	PTS system
C6W73_RS15670	COG3716	PTS system mannose fructose sorbose family IID component
C6W73_RS15685	COG0501	Belongs to the peptidase M48B family
C6W73_RS15690	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C6W73_RS15695	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6W73_RS15700	COG2213	PTS system mannitol-specific
C6W73_RS15705	COG1063	alcohol dehydrogenase
C6W73_RS15710	COG1494	fructose-1,6-bisphosphatase
C6W73_RS15720	COG1072	(Pantothenic acid kinase))
C6W73_RS15740	COG0191	fructose-bisphosphate aldolase activity
C6W73_RS15750	COG0668	transmembrane transport
C6W73_RS15755	COG1279	arginine transmembrane transporter activity
C6W73_RS15760	COG2968	Membrane
C6W73_RS15765	COG0583	DNA-binding transcription factor activity
C6W73_RS15770	COG0427	acetyl-CoA hydrolase
C6W73_RS15775	COG1024	Enoyl-CoA hydratase
C6W73_RS15780	COG1703	isobutyryl-CoA mutase activity
C6W73_RS15785	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C6W73_RS15785	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C6W73_RS15805	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C6W73_RS15825	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C6W73_RS15850	COG0006	proline dipeptidase activity
C6W73_RS15855	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C6W73_RS15880	COG1028	Short-chain dehydrogenase reductase Sdr
C6W73_RS15885	COG2723	6-phospho-beta-galactosidase activity
C6W73_RS15895	COG1272	protein, Hemolysin III
C6W73_RS15905	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
C6W73_RS15915	COG0716	FMN binding
C6W73_RS15920	COG4974	Belongs to the 'phage' integrase family
C6W73_RS15925	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C6W73_RS15930	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C6W73_RS15955	COG2233	PERMEase
C6W73_RS15965	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6W73_RS15965	COG0493	'glutamate synthase
C6W73_RS15970	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6W73_RS15975	COG2252	PERMEase
C6W73_RS15980	COG0402	S-adenosylhomocysteine deaminase activity
C6W73_RS15985	COG2233	PERMEase
C6W73_RS15990	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C6W73_RS15990	COG2080	2 iron, 2 sulfur cluster binding
C6W73_RS15995	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C6W73_RS16000	COG0402	S-adenosylhomocysteine deaminase activity
C6W73_RS16005	COG0493	'glutamate synthase
C6W73_RS16005	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6W73_RS16010	COG2068	MobA-Related Protein
C6W73_RS16015	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C6W73_RS16020	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C6W73_RS16020	COG3608	succinylglutamate desuccinylase aspartoacylase
C6W73_RS16025	COG0549	Belongs to the carbamate kinase family
C6W73_RS16035	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C6W73_RS16040	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C6W73_RS16045	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C6W73_RS16050	COG3829	transcription factor binding
C6W73_RS16055	COG2080	2 iron, 2 sulfur cluster binding
C6W73_RS16060	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C6W73_RS16065	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C6W73_RS16075	COG4942	peptidase
C6W73_RS16085	COG3387	PFAM Glycoside hydrolase 15-related
C6W73_RS16170	COG2197	response regulator
C6W73_RS16175	COG2197	response regulator
C6W73_RS16195	COG3710	Transcriptional regulator
C6W73_RS16195	COG0457	Tetratricopeptide repeat
C6W73_RS16200	COG0457	Tetratricopeptide repeat
C6W73_RS16225	COG3710	Transcriptional regulator
C6W73_RS16230	COG2771	luxR family
C6W73_RS16235	COG0814	amino acid
C6W73_RS16240	COG0183	Belongs to the thiolase family
C6W73_RS16250	COG1028	Short-chain dehydrogenase reductase Sdr
C6W73_RS16255	COG2814	Major facilitator Superfamily
C6W73_RS16260	COG1794	racemase activity, acting on amino acids and derivatives
C6W73_RS16265	COG0583	DNA-binding transcription factor activity
C6W73_RS16275	COG1609	Transcriptional regulator
C6W73_RS16290	COG0667	Aldo Keto reductase
C6W73_RS16300	COG0861	Integral membrane protein TerC family
C6W73_RS16315	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
C6W73_RS16335	COG2165	general secretion pathway protein
C6W73_RS16340	COG4795	General secretion pathway protein
C6W73_RS16350	COG4967	type IV pilus modification protein PilV
C6W73_RS16355	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
C6W73_RS16360	COG1025	Belongs to the peptidase M16 family
C6W73_RS16370	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C6W73_RS16375	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C6W73_RS16375	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C6W73_RS16385	COG0860	N-Acetylmuramoyl-L-alanine amidase
C6W73_RS16490	COG2885	chlorophyll binding
C6W73_RS16535	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
C6W73_RS16540	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C6W73_RS16545	COG2166	iron-sulfur cluster assembly
C6W73_RS16550	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C6W73_RS16560	COG0583	DNA-binding transcription factor activity
C6W73_RS16565	COG2363	Small membrane protein
C6W73_RS16575	COG1349	DNA-binding transcription factor activity
C6W73_RS16585	COG1070	Carbohydrate kinase
C6W73_RS16595	COG0738	Major facilitator superfamily
C6W73_RS16600	COG0235	Class ii aldolase
C6W73_RS16605	COG1454	alcohol dehydrogenase
C6W73_RS16615	COG1760	l-serine dehydratase
C6W73_RS16620	COG0814	amino acid
C6W73_RS16625	COG1611	Belongs to the LOG family
C6W73_RS16640	COG3098	single-species biofilm formation
C6W73_RS16645	COG0564	pseudouridine synthase activity
C6W73_RS16650	COG0716	FMN binding
C6W73_RS16655	COG2271	Major facilitator Superfamily
C6W73_RS16660	COG4948	Mandelate Racemase Muconate Lactonizing
C6W73_RS16665	COG4948	Mandelate Racemase Muconate Lactonizing
C6W73_RS16670	COG3437	response regulator, receiver
C6W73_RS16670	COG4999	Histidine kinase
C6W73_RS16670	COG2205	protein histidine kinase activity
C6W73_RS16670	COG3850	Histidine kinase
C6W73_RS16680	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C6W73_RS16685	COG2336	PFAM SpoVT AbrB
C6W73_RS16690	COG2337	Toxic component of a toxin-antitoxin (TA) module
C6W73_RS16695	COG3956	TIGRFAM MazG family protein
C6W73_RS16710	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
C6W73_RS16720	COG0602	queuosine metabolic process
C6W73_RS16725	COG1070	Carbohydrate kinase
C6W73_RS16730	COG2223	nitrite transmembrane transporter activity
C6W73_RS16735	COG1028	Short-chain dehydrogenase reductase Sdr
C6W73_RS16740	COG0277	FAD linked oxidase domain protein
C6W73_RS16745	COG0477	Major facilitator Superfamily
C6W73_RS16750	COG2086	electron transfer activity
C6W73_RS16755	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C6W73_RS16760	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
C6W73_RS16765	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C6W73_RS16770	COG0644	oxidoreductase
C6W73_RS16775	COG0720	synthase
C6W73_RS16805	COG1203	CRISPR-associated helicase, Cas3
C6W73_RS16820	COG1857	crispr-associated protein
C6W73_RS16835	COG1518	maintenance of DNA repeat elements
C6W73_RS16840	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6W73_RS16845	COG2234	aminopeptidase activity
C6W73_RS16900	COG4942	peptidase
C6W73_RS16900	COG1388	LysM domain
C6W73_RS16905	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C6W73_RS16920	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C6W73_RS16930	COG2610	gluconate transmembrane transporter activity
C6W73_RS16935	COG3622	Belongs to the hyi family
C6W73_RS16940	COG0235	Class ii aldolase
C6W73_RS16945	COG3395	kinase activity
C6W73_RS16950	COG2084	Dehydrogenase
C6W73_RS16955	COG1349	DNA-binding transcription factor activity
C6W73_RS16960	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C6W73_RS16975	COG3604	Transcriptional regulator
C6W73_RS16980	COG0309	Hydrogenase expression formation protein (HypE)
C6W73_RS16985	COG0409	Hydrogenase expression formation protein
C6W73_RS16990	COG0298	carbon dioxide binding
C6W73_RS16995	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
C6W73_RS17000	COG0375	protein maturation
C6W73_RS17010	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6W73_RS17015	COG0651	ATP synthesis coupled electron transport
C6W73_RS17020	COG0650	Formate hydrogenlyase subunit 4
C6W73_RS17025	COG3261	NADH dehydrogenase
C6W73_RS17025	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
C6W73_RS17030	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C6W73_RS17035	COG3260	NADH ubiquinone oxidoreductase 20
C6W73_RS17045	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C6W73_RS17055	COG5499	transcription regulator containing HTH domain
C6W73_RS17065	COG3547	Transposase (IS116 IS110 IS902 family)
C6W73_RS17070	COG2723	6-phospho-beta-galactosidase activity
C6W73_RS17075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6W73_RS17075	COG1263	PTS System
C6W73_RS17080	COG1609	Transcriptional regulator
C6W73_RS17085	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6W73_RS17090	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
C6W73_RS17115	COG1349	DNA-binding transcription factor activity
C6W73_RS17120	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6W73_RS17125	COG1028	Short-chain dehydrogenase reductase Sdr
C6W73_RS17130	COG3731	PTS system glucitol sorbitol-specific IIA component
C6W73_RS17135	COG3732	PTS system glucitol sorbitol-specific
C6W73_RS17140	COG3730	PTS system glucitol sorbitol-specific
C6W73_RS17145	COG2951	lytic endotransglycosylase activity
C6W73_RS17150	COG1546	Belongs to the CinA family
C6W73_RS17170	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
C6W73_RS17200	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C6W73_RS17205	COG1238	metal cluster binding
C6W73_RS17220	COG2814	Major facilitator Superfamily
C6W73_RS17225	COG1566	PFAM secretion protein HlyD family protein
C6W73_RS17230	COG1846	Transcriptional regulator
C6W73_RS17240	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
C6W73_RS17245	COG2814	Major facilitator Superfamily
C6W73_RS17250	COG2113	Glycine betaine
C6W73_RS17255	COG4176	ABC-type proline glycine betaine transport system permease component
C6W73_RS17260	COG4175	Glycine betaine
C6W73_RS17265	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C6W73_RS17270	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C6W73_RS17280	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C6W73_RS17285	COG4575	ribosome binding
C6W73_RS17300	COG2916	Histone family protein nucleoid-structuring protein H-NS
C6W73_RS17305	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C6W73_RS17310	COG0640	Transcriptional regulator
C6W73_RS17315	COG0401	homolog of Blt101
C6W73_RS17320	COG1652	LysM domain
C6W73_RS17325	COG1802	Transcriptional regulator
C6W73_RS17335	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C6W73_RS17340	COG1012	belongs to the aldehyde dehydrogenase family
C6W73_RS17345	COG0579	oxidoreductase
C6W73_RS17355	COG0366	Alpha amylase catalytic
C6W73_RS17380	COG0582	viral genome integration into host DNA
C6W73_RS17395	COG2867	negative regulation of translational initiation
C6W73_RS17405	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C6W73_RS17410	COG0497	DNA recombination
C6W73_RS17430	COG4536	flavin adenine dinucleotide binding
C6W73_RS17435	COG4137	Cytochrome C assembly protein
C6W73_RS17440	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C6W73_RS17465	COG2885	chlorophyll binding
C6W73_RS17470	COG2199	diguanylate cyclase activity
C6W73_RS17485	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C6W73_RS17490	COG0287	Prephenate dehydrogenase
C6W73_RS17490	COG1605	Chorismate mutase
C6W73_RS17495	COG0077	Prephenate dehydratase
C6W73_RS17495	COG1605	Chorismate mutase
C6W73_RS17505	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C6W73_RS17515	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C6W73_RS17520	COG0564	pseudouridine synthase activity
C6W73_RS17525	COG1496	oxidoreductase activity
C6W73_RS17530	COG0542	response to heat
C6W73_RS17560	COG0477	Major facilitator Superfamily
C6W73_RS17565	COG5544	Lipoprotein
C6W73_RS17570	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C6W73_RS17575	COG0045	succinate-CoA ligase (ADP-forming) activity
C6W73_RS17575	COG1042	CoA-binding domain protein
C6W73_RS17575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C6W73_RS17580	COG3148	PFAM DTW domain containing protein
C6W73_RS17585	COG3118	belongs to the thioredoxin family
C6W73_RS17595	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C6W73_RS17615	COG0583	DNA-binding transcription factor activity
C6W73_RS17620	COG0513	Belongs to the DEAD box helicase family
C6W73_RS17630	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C6W73_RS17635	COG1595	DNA-templated transcription, initiation
C6W73_RS17640	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
C6W73_RS17645	COG3026	antisigma factor binding
C6W73_RS17650	COG3086	response to oxidative stress
C6W73_RS17660	COG0681	Belongs to the peptidase S26 family
C6W73_RS17685	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
C6W73_RS17710	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6W73_RS17715	COG1737	Transcriptional regulator
C6W73_RS17720	COG0560	Phosphoserine phosphatase
C6W73_RS17740	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C6W73_RS17740	COG0047	phosphoribosylformylglycinamidine synthase activity
C6W73_RS17745	COG2205	protein histidine kinase activity
C6W73_RS17750	COG3170	Tfp pilus assembly protein FimV
C6W73_RS17755	COG2204	response regulator
C6W73_RS17760	COG0347	Belongs to the P(II) protein family
C6W73_RS17765	COG1017	nitric oxide dioxygenase activity
C6W73_RS17765	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C6W73_RS17775	COG1940	carbohydrate kinase activity
C6W73_RS17785	COG1879	ABC-type sugar transport system periplasmic component
C6W73_RS17790	COG1129	ABC transporter
C6W73_RS17795	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6W73_RS17800	COG1063	alcohol dehydrogenase
C6W73_RS17805	COG2017	converts alpha-aldose to the beta-anomer
C6W73_RS17810	COG2259	Doxx family
C6W73_RS17835	COG4638	Rieske (2fe-2S)
C6W73_RS17840	COG0583	DNA-binding transcription factor activity
C6W73_RS17845	COG2814	Major facilitator Superfamily
C6W73_RS17850	COG3711	transcriptional antiterminator
C6W73_RS17855	COG1073	alpha beta
C6W73_RS17860	COG0483	inositol monophosphate 1-phosphatase activity
C6W73_RS17880	COG0822	iron-sulfur transferase activity
C6W73_RS17900	COG0633	Ferredoxin
C6W73_RS17905	COG2975	iron-sulfur cluster assembly
C6W73_RS17920	COG2897	thiosulfate sulfurtransferase activity
C6W73_RS17925	COG2373	Large extracellular alpha-helical protein
C6W73_RS17930	COG4953	penicillin-binding protein 1C
C6W73_RS17965	COG2976	Protein conserved in bacteria
C6W73_RS17980	COG1645	bacterial-type flagellum-dependent swarming motility
C6W73_RS17990	COG0517	IMP dehydrogenase activity
C6W73_RS17990	COG0516	GMP reductase activity
C6W73_RS18005	COG3133	Outer membrane lipoprotein
C6W73_RS18025	COG2200	EAL domain
C6W73_RS18030	COG0248	Ppx GppA phosphatase
C6W73_RS18035	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
C6W73_RS18040	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C6W73_RS18060	COG2233	PERMEase
C6W73_RS18070	COG1393	Belongs to the ArsC family
C6W73_RS18075	COG4783	chaperone-mediated protein folding
C6W73_RS18080	COG0628	permease
C6W73_RS18090	COG2116	formate transmembrane transporter activity
C6W73_RS18095	COG3604	Transcriptional regulator
C6W73_RS18105	COG3260	NADH ubiquinone oxidoreductase 20
C6W73_RS18110	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C6W73_RS18115	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
C6W73_RS18115	COG3261	NADH dehydrogenase
C6W73_RS18125	COG4237	Hydrogenase 4 membrane
C6W73_RS18135	COG0650	Formate hydrogenlyase subunit 4
C6W73_RS18145	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6W73_RS18150	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C6W73_RS18155	COG2716	regulation of RNA biosynthetic process
C6W73_RS18165	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
C6W73_RS18185	COG2321	neutral zinc metallopeptidase
C6W73_RS18195	COG0400	carboxylic ester hydrolase activity
C6W73_RS18210	COG1393	Belongs to the ArsC family
C6W73_RS18225	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C6W73_RS18230	COG3850	Histidine kinase
C6W73_RS18235	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6W73_RS18235	COG0493	'glutamate synthase
C6W73_RS18245	COG5342	invasion associated locus B
C6W73_RS18250	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C6W73_RS18255	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C6W73_RS18260	COG0281	malic enzyme
C6W73_RS18260	COG0280	phosphate acetyltransferase
C6W73_RS18270	COG4810	utilization protein
C6W73_RS18275	COG4917	ethanolamine utilization protein
C6W73_RS18280	COG4766	ethanolamine catabolic process
C6W73_RS18285	COG4812	Cobalamin adenosyltransferase
C6W73_RS18290	COG0280	phosphate acetyltransferase
C6W73_RS18295	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
C6W73_RS18300	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
C6W73_RS18305	COG1012	belongs to the aldehyde dehydrogenase family
C6W73_RS18310	COG4820	ethanolamine utilization protein (EutJ)
C6W73_RS18315	COG1454	alcohol dehydrogenase
C6W73_RS18320	COG3192	ethanolamine utilization protein
C6W73_RS18325	COG4819	ethanolamine utilization protein
C6W73_RS18330	COG4303	Ethanolamine ammonia lyase large subunit
C6W73_RS18340	COG4816	utilization protein
C6W73_RS18345	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
C6W73_RS18350	COG2207	Transcriptional regulator
C6W73_RS18360	COG0860	N-Acetylmuramoyl-L-alanine amidase
C6W73_RS18380	COG2837	iron assimilation
C6W73_RS18385	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C6W73_RS18390	COG1263	PTS System
C6W73_RS18390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6W73_RS18405	COG1028	Short-chain dehydrogenase reductase Sdr
C6W73_RS18410	COG4150	thiosulfate binding
C6W73_RS18415	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
C6W73_RS18420	COG4208	sulfate ABC transporter
C6W73_RS18425	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C6W73_RS18430	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C6W73_RS18445	COG2190	(PTS) system
C6W73_RS18450	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C6W73_RS18455	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6W73_RS18460	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C6W73_RS18480	COG3530	Putative quorum-sensing-regulated virulence factor
C6W73_RS18485	COG0385	Bile acid
C6W73_RS18490	COG0583	DNA-binding transcription factor activity
C6W73_RS18530	COG3415	Transposase
C6W73_RS18535	COG3415	Transposase
C6W73_RS18550	COG2200	EAL domain
C6W73_RS18550	COG2199	diguanylate cyclase activity
C6W73_RS18555	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C6W73_RS18580	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6W73_RS18585	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6W73_RS18590	COG0006	proline dipeptidase activity
C6W73_RS18595	COG1363	Peptidase, m42
C6W73_RS18605	COG2207	Transcriptional regulator
C6W73_RS18610	COG3279	Response regulator of the LytR AlgR family
C6W73_RS18615	COG3275	phosphorelay sensor kinase activity
C6W73_RS18620	COG0436	Aminotransferase
C6W73_RS18630	COG1560	Kdo2-lipid A biosynthetic process
C6W73_RS18660	COG0028	Belongs to the TPP enzyme family
C6W73_RS18665	COG0679	Auxin Efflux Carrier
C6W73_RS18670	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C6W73_RS18675	COG0784	Response regulator, receiver
C6W73_RS18675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6W73_RS18675	COG2198	Histidine kinase
C6W73_RS18675	COG2205	protein histidine kinase activity
C6W73_RS18680	COG2197	response regulator
C6W73_RS18685	COG1566	PFAM secretion protein HlyD family protein
C6W73_RS18690	COG0477	Major facilitator Superfamily
C6W73_RS18730	COG2116	formate transmembrane transporter activity
C6W73_RS18740	COG2853	Lipoprotein
C6W73_RS18755	COG2067	long-chain fatty acid transport protein
C6W73_RS18765	COG3691	Protein conserved in bacteria
C6W73_RS18780	COG2062	phosphohistidine phosphatase, SixA
C6W73_RS18785	COG3539	Fimbrial protein
C6W73_RS18790	COG3188	usher protein
C6W73_RS18795	COG3121	Chaperone
C6W73_RS18800	COG3539	Fimbrial protein
C6W73_RS18805	COG3539	Fimbrial protein
C6W73_RS18810	COG3539	Fimbrial protein
C6W73_RS18840	COG0730	response to heat
C6W73_RS18845	COG3101	peptidyl-lysine hydroxylation
C6W73_RS18860	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C6W73_RS18870	COG2814	Major facilitator Superfamily
C6W73_RS18885	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C6W73_RS18895	COG0586	Pfam SNARE associated Golgi protein
C6W73_RS18905	COG0285	dihydrofolate synthase activity
C6W73_RS18910	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
C6W73_RS18915	COG1286	toxin biosynthetic process
C6W73_RS18920	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C6W73_RS18925	COG0163	prenyltransferase activity
C6W73_RS18930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6W73_RS18935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6W73_RS18940	COG4215	(ABC) transporter
C6W73_RS18945	COG4160	amino acid transport
C6W73_RS18950	COG4598	ABC transporter
C6W73_RS18955	COG5464	transposase or invertase
C6W73_RS18960	COG1090	epimerase
C6W73_RS18965	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C6W73_RS18970	COG0625	glutathione transferase activity
C6W73_RS18975	COG0625	glutathione transferase activity
C6W73_RS18980	COG0622	Phosphoesterase
C6W73_RS18985	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
C6W73_RS18990	COG1288	antiporter activity
C6W73_RS18995	COG0280	phosphate acetyltransferase
C6W73_RS18995	COG0857	belongs to the CobB CobQ family
C6W73_RS19000	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C6W73_RS19015	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C6W73_RS19020	COG0490	domain, Protein
C6W73_RS19020	COG0471	metal ion transport
C6W73_RS19030	COG0436	Aminotransferase
C6W73_RS19040	COG0583	DNA-binding transcription factor activity
C6W73_RS19060	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
C6W73_RS19065	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
C6W73_RS19070	COG1034	ATP synthesis coupled electron transport
C6W73_RS19085	COG0839	Belongs to the complex I subunit 6 family
C6W73_RS19095	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C6W73_RS19100	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C6W73_RS19115	COG2234	aminopeptidase activity
C6W73_RS19135	COG2153	protein acetylation
C6W73_RS19140	COG4575	ribosome binding
C6W73_RS19145	COG1169	isochorismate synthase
C6W73_RS19160	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C6W73_RS19170	COG0318	PFAM AMP-dependent synthetase and ligase
C6W73_RS19240	COG5464	transposase or invertase
C6W73_RS19245	COG0247	lactate metabolic process
C6W73_RS19255	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C6W73_RS19265	COG2271	Major facilitator Superfamily
C6W73_RS19270	COG0584	glycerophosphoryl diester phosphodiesterase
C6W73_RS19275	COG0583	DNA-binding transcription factor activity
C6W73_RS19280	COG3642	lipopolysaccharide core region biosynthetic process
C6W73_RS19285	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C6W73_RS19290	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C6W73_RS19295	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C6W73_RS19315	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C6W73_RS19320	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
C6W73_RS19325	COG3234	Protein of unknown function (DUF1175)
C6W73_RS19330	COG2373	Large extracellular alpha-helical protein
C6W73_RS19335	COG5445	Predicted secreted protein (DUF2300)
C6W73_RS19340	COG4676	Protein conserved in bacteria
C6W73_RS19345	COG0784	Response regulator, receiver
C6W73_RS19345	COG2205	protein histidine kinase activity
C6W73_RS19350	COG2197	response regulator
C6W73_RS19355	COG0642	Histidine kinase
C6W73_RS19355	COG2198	Histidine kinase
C6W73_RS19375	COG1477	protein flavinylation
C6W73_RS19380	COG2169	Transcriptional regulator
C6W73_RS19380	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C6W73_RS19385	COG3145	DNA-N1-methyladenine dioxygenase activity
C6W73_RS19390	COG4615	Cyclic peptide transporter
C6W73_RS19410	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6W73_RS19410	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6W73_RS19415	COG3062	negative regulation of establishment of protein localization
C6W73_RS19425	COG0437	4 iron, 4 sulfur cluster binding
C6W73_RS19430	COG0348	domain, Protein
C6W73_RS19435	COG3043	anaerobic respiration
C6W73_RS19440	COG3005	denitrification pathway
C6W73_RS19445	COG4133	protoheme IX ABC transporter activity
C6W73_RS19450	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C6W73_RS19455	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C6W73_RS19460	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C6W73_RS19470	COG1138	Cytochrome C-type biogenesis protein
C6W73_RS19475	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C6W73_RS19480	COG4235	cytochrome complex assembly
C6W73_RS19480	COG3088	subunit of a heme lyase
C6W73_RS19485	COG2197	response regulator
C6W73_RS19495	COG3468	outer membrane autotransporter barrel domain protein
C6W73_RS19500	COG3468	outer membrane autotransporter barrel domain protein
C6W73_RS19510	COG3083	sulfuric ester hydrolase activity
C6W73_RS19530	COG1061	Type III restriction enzyme res subunit
C6W73_RS19540	COG1187	pseudouridine synthase activity
C6W73_RS19545	COG2814	Major facilitator Superfamily
C6W73_RS19560	COG4172	Belongs to the ABC transporter superfamily
C6W73_RS19565	COG4239	(ABC) transporter, permease
C6W73_RS19570	COG4174	ABC transporter (Permease)
C6W73_RS19575	COG4166	transmembrane transport
C6W73_RS19580	COG2200	EAL domain
C6W73_RS19585	COG0791	NLP P60 protein
C6W73_RS19590	COG0671	phosphoesterase, PA-phosphatase related
C6W73_RS19595	COG0523	cobalamin synthesis protein
C6W73_RS19600	COG0246	Mannitol dehydrogenase
C6W73_RS19615	COG2814	Major facilitator Superfamily
C6W73_RS19620	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6W73_RS19620	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6W73_RS19625	COG1105	Belongs to the carbohydrate kinase PfkB family
C6W73_RS19630	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6W73_RS19630	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
C6W73_RS19630	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6W73_RS19635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6W73_RS19640	COG2313	pseudouridylate synthase activity
C6W73_RS19645	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C6W73_RS19650	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C6W73_RS19660	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C6W73_RS19665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6W73_RS19665	COG1522	sequence-specific DNA binding
C6W73_RS19675	COG2855	membrane
C6W73_RS19680	COG0583	DNA-binding transcription factor activity
C6W73_RS19690	COG0833	amino acid
C6W73_RS19700	COG4771	TonB-dependent receptor
C6W73_RS19725	COG2311	Membrane
C6W73_RS19735	COG1609	Transcriptional regulator
C6W73_RS19740	COG1879	ABC-type sugar transport system periplasmic component
C6W73_RS19745	COG1129	ABC transporter
C6W73_RS19750	COG4211	Belongs to the binding-protein-dependent transport system permease family
C6W73_RS19755	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
C6W73_RS19755	COG0167	dihydroorotate dehydrogenase activity
C6W73_RS19760	COG0493	'glutamate synthase
C6W73_RS19770	COG2949	membrane
C6W73_RS19780	COG1346	cytolysis
C6W73_RS19790	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C6W73_RS19815	COG1028	Short-chain dehydrogenase reductase Sdr
C6W73_RS19820	COG0586	Pfam SNARE associated Golgi protein
C6W73_RS19830	COG1686	Belongs to the peptidase S11 family
C6W73_RS19835	COG0277	FAD linked oxidase domain protein
C6W73_RS19840	COG1472	Belongs to the glycosyl hydrolase 3 family
C6W73_RS19845	COG1732	Glycine betaine
C6W73_RS19850	COG1174	glycine betaine transport
C6W73_RS19855	COG1125	glycine betaine transport
C6W73_RS19860	COG1174	glycine betaine transport
C6W73_RS19870	COG0789	Transcriptional regulator
C6W73_RS19875	COG0582	viral genome integration into host DNA
C6W73_RS19925	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C6W73_RS19945	COG3646	Phage regulatory protein
C6W73_RS19955	COG4626	Terminase
C6W73_RS19955	COG1802	Transcriptional regulator
C6W73_RS19960	COG1484	DNA-dependent DNA replication
C6W73_RS19965	COG0305	Participates in initiation and elongation during chromosome replication
C6W73_RS19975	COG1403	HNH endonuclease
C6W73_RS20055	COG3772	lysozyme
C6W73_RS20070	COG3646	Phage regulatory protein
C6W73_RS20085	COG4220	transposase activity
C6W73_RS20190	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6W73_RS20215	COG3275	phosphorelay sensor kinase activity
C6W73_RS20220	COG3279	Response regulator of the LytR AlgR family
C6W73_RS20225	COG4807	Protein conserved in bacteria
C6W73_RS20230	COG4808	Protein conserved in bacteria
C6W73_RS20235	COG4715	Zinc finger, swim domain protein
C6W73_RS20240	COG3552	Protein containing von Willebrand factor type A (VWA) domain
C6W73_RS20245	COG2425	protein containing a von Willebrand factor type A (vWA) domain
C6W73_RS20250	COG0714	Associated with various cellular activities
C6W73_RS20260	COG3831	ATPase activity
C6W73_RS20265	COG3831	ATPase activity
C6W73_RS20275	COG0489	protein tyrosine kinase activity
C6W73_RS20290	COG3539	Fimbrial protein
C6W73_RS20295	COG3121	Chaperone
C6W73_RS20300	COG3188	usher protein
C6W73_RS20305	COG3539	Fimbrial protein
C6W73_RS20310	COG5455	response to cobalt ion
C6W73_RS20330	COG0351	phosphomethylpyrimidine kinase
C6W73_RS20335	COG3757	hydrolase, family 25
C6W73_RS20340	COG2188	Transcriptional regulator
C6W73_RS20345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6W73_RS20350	COG1397	ADP-ribosylglycohydrolase
C6W73_RS20355	COG2211	Major facilitator Superfamily
C6W73_RS20360	COG1830	Aldolase
C6W73_RS20375	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6W73_RS20380	COG3414	Phosphotransferase system galactitol-specific IIB component
C6W73_RS20385	COG3775	system Galactitol-specific IIC component
C6W73_RS20390	COG1063	alcohol dehydrogenase
C6W73_RS20415	COG0826	peptidase U32
C6W73_RS20425	COG3609	addiction module antidote protein, CC2985 family
C6W73_RS20435	COG0745	RESPONSE REGULATOR receiver
C6W73_RS20440	COG2205	protein histidine kinase activity
C6W73_RS20480	COG4245	von Willebrand factor, type A
C6W73_RS20485	COG0631	protein serine/threonine phosphatase activity
C6W73_RS20490	COG3779	Protein conserved in bacteria
C6W73_RS20495	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
C6W73_RS20500	COG0443	Heat shock 70 kDa protein
C6W73_RS20505	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C6W73_RS20510	COG5001	Diguanylate cyclase
C6W73_RS20510	COG3447	MASE1 domain protein
C6W73_RS20510	COG5002	protein histidine kinase activity
C6W73_RS20515	COG0572	uridine kinase
C6W73_RS20525	COG2982	Protein involved in outer membrane biogenesis
C6W73_RS20530	COG1253	flavin adenine dinucleotide binding
C6W73_RS20535	COG1596	polysaccharide export
C6W73_RS20540	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C6W73_RS20545	COG0489	protein tyrosine kinase activity
C6W73_RS20545	COG3206	protein involved in exopolysaccharide biosynthesis
C6W73_RS20550	COG0463	Glycosyl transferase, family 2
C6W73_RS20555	COG1045	serine acetyltransferase
C6W73_RS20560	COG0438	transferase activity, transferring glycosyl groups
C6W73_RS20570	COG1216	Glycosyl transferase, family 2
C6W73_RS20575	COG0110	maltose O-acetyltransferase activity
C6W73_RS20580	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
C6W73_RS20585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C6W73_RS20590	COG1051	belongs to the nudix hydrolase family
C6W73_RS20595	COG0297	glycogen (starch) synthase activity
C6W73_RS20600	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
C6W73_RS20600	COG0662	Cupin 2, conserved barrel domain protein
C6W73_RS20605	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C6W73_RS20610	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C6W73_RS20615	COG2244	polysaccharide biosynthetic process
C6W73_RS20620	COG2327	Polysaccharide pyruvyl transferase
C6W73_RS20625	COG0438	transferase activity, transferring glycosyl groups
C6W73_RS20635	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C6W73_RS20655	COG1086	Polysaccharide biosynthesis protein
C6W73_RS20685	COG2244	polysaccharide biosynthetic process
C6W73_RS20695	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C6W73_RS20700	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C6W73_RS20705	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C6W73_RS20710	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
C6W73_RS20735	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C6W73_RS20740	COG0131	Imidazoleglycerol-phosphate dehydratase
C6W73_RS20740	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C6W73_RS20770	COG2161	toxin-antitoxin pair type II binding
C6W73_RS20775	COG4115	mRNA cleavage
C6W73_RS20780	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C6W73_RS20785	COG0583	DNA-binding transcription factor activity
C6W73_RS20795	COG0531	amino acid
C6W73_RS20800	COG2391	methyltransferase activity
C6W73_RS20805	COG0425	Belongs to the sulfur carrier protein TusA family
C6W73_RS20810	COG2925	Exonuclease
C6W73_RS20815	COG1686	Belongs to the peptidase S11 family
C6W73_RS20835	COG3547	Transposase (IS116 IS110 IS902 family)
C6W73_RS20850	COG4917	ethanolamine utilization protein
C6W73_RS20855	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
C6W73_RS20870	COG1376	ErfK ybiS ycfS ynhG family protein
C6W73_RS20880	COG0583	DNA-binding transcription factor activity
C6W73_RS20885	COG0583	DNA-binding transcription factor activity
C6W73_RS20910	COG0217	transcriptional regulatory protein
C6W73_RS20915	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C6W73_RS20920	COG0477	Major facilitator Superfamily
C6W73_RS20940	COG1388	LysM domain
C6W73_RS20940	COG1470	cell adhesion involved in biofilm formation
C6W73_RS20965	COG3038	cytochrome b561
C6W73_RS20970	COG3443	Belongs to the bacterial solute-binding protein 9 family
C6W73_RS20985	COG2351	hydroxyisourate hydrolase activity
C6W73_RS20990	COG0745	RESPONSE REGULATOR receiver
C6W73_RS20995	COG2205	protein histidine kinase activity
C6W73_RS21010	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C6W73_RS21020	COG1418	mRNA catabolic process
C6W73_RS21025	COG0270	DNA (cytosine-5-)-methyltransferase activity
C6W73_RS21030	COG3727	T/G mismatch-specific endonuclease activity
C6W73_RS21035	COG0697	spore germination
C6W73_RS21040	COG2354	Protein conserved in bacteria
C6W73_RS21045	COG5475	Uncharacterized small protein (DUF2158)
C6W73_RS21075	COG2197	response regulator
C6W73_RS21080	COG1684	flagellar biosynthetic protein fliR
C6W73_RS21085	COG1987	bacterial-type flagellum assembly
C6W73_RS21090	COG1338	Plays a role in the flagellum-specific transport system
C6W73_RS21095	COG3190	flagellar
C6W73_RS21100	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C6W73_RS21105	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C6W73_RS21110	COG1580	Controls the rotational direction of flagella during chemotaxis
C6W73_RS21115	COG3144	bacterial-type flagellum assembly
C6W73_RS21120	COG2882	bacterial-type flagellum organization
C6W73_RS21125	COG1157	protein secretion by the type III secretion system
C6W73_RS21130	COG1317	bacterial-type flagellum organization
C6W73_RS21135	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C6W73_RS21140	COG1766	The M ring may be actively involved in energy transduction
C6W73_RS21155	COG2135	peptidase activity
C6W73_RS21160	COG0425	Belongs to the sulfur carrier protein TusA family
C6W73_RS21165	COG2391	methyltransferase activity
C6W73_RS21180	COG0366	Alpha amylase catalytic
C6W73_RS21190	COG1516	flagellar protein fliS
C6W73_RS21195	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C6W73_RS21210	COG1191	sigma factor activity
C6W73_RS21220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6W73_RS21230	COG0765	amino acid transport
C6W73_RS21235	COG1126	abc transporter atp-binding protein
C6W73_RS21240	COG2197	response regulator
C6W73_RS21250	COG2197	response regulator
C6W73_RS21280	COG3012	SEC-C Motif Domain Protein
C6W73_RS21280	COG3318	Belongs to the UPF0149 family
C6W73_RS21285	COG0814	amino acid
C6W73_RS21295	COG1528	Iron-storage protein
C6W73_RS21315	COG1528	Iron-storage protein
C6W73_RS21325	COG1879	ABC-type sugar transport system periplasmic component
C6W73_RS21330	COG1129	ABC transporter
C6W73_RS21335	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6W73_RS21340	COG1877	trehalose-phosphatase activity
C6W73_RS21350	COG0589	response to stress
C6W73_RS21365	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C6W73_RS21370	COG1360	Flagellar Motor Protein
C6W73_RS21375	COG2198	Histidine kinase
C6W73_RS21375	COG0643	Histidine kinase
C6W73_RS21380	COG0835	chemotaxis
C6W73_RS21385	COG0840	transmembrane signaling receptor activity
C6W73_RS21390	COG0840	transmembrane signaling receptor activity
C6W73_RS21395	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C6W73_RS21400	COG2201	protein-glutamate methylesterase activity
C6W73_RS21405	COG0745	RESPONSE REGULATOR receiver
C6W73_RS21410	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
C6W73_RS21415	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C6W73_RS21420	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C6W73_RS21430	COG3755	Protein conserved in bacteria
C6W73_RS21445	COG3102	Protein conserved in bacteria
C6W73_RS21455	COG3005	denitrification pathway
C6W73_RS21460	COG0243	molybdopterin cofactor binding
C6W73_RS21470	COG3547	Transposase (IS116 IS110 IS902 family)
C6W73_RS21485	COG3788	relative of glutathione S-transferase, MAPEG superfamily
C6W73_RS21490	COG1801	Protein of unknown function DUF72
C6W73_RS21495	COG1335	isochorismatase
C6W73_RS21505	COG0494	nUDIX hydrolase
C6W73_RS21510	COG0217	transcriptional regulatory protein
C6W73_RS21540	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C6W73_RS21550	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
C6W73_RS21555	COG0739	heme binding
C6W73_RS21560	COG1560	Kdo2-lipid A biosynthetic process
C6W73_RS21565	COG0469	pyruvate kinase activity
C6W73_RS21570	COG1737	Transcriptional regulator
C6W73_RS21575	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C6W73_RS21580	COG0129	dihydroxy-acid dehydratase activity
C6W73_RS21585	COG0800	Aldolase
C6W73_RS21595	COG3141	response to X-ray
C6W73_RS21605	COG2979	Protein of unknown function (DUF533)
C6W73_RS21610	COG1770	oligopeptidase
C6W73_RS21615	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6W73_RS21620	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C6W73_RS21630	COG2372	response to copper ion
C6W73_RS21635	COG1276	copper resistance
C6W73_RS21645	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C6W73_RS21665	COG3008	intermembrane lipid transfer
C6W73_RS21670	COG2995	paraquat-inducible protein a
C6W73_RS21675	COG1956	GAF domain-containing protein
C6W73_RS21685	COG0793	Belongs to the peptidase S41A family
C6W73_RS21695	COG2814	Major facilitator Superfamily
C6W73_RS21700	COG1414	Transcriptional regulator
C6W73_RS21735	COG2226	methyltransferase
C6W73_RS21760	COG3715	PTS system
C6W73_RS21765	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6W73_RS21765	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6W73_RS21780	COG1253	flavin adenine dinucleotide binding
C6W73_RS21785	COG2200	EAL domain
C6W73_RS21790	COG1760	l-serine dehydratase
C6W73_RS21800	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C6W73_RS21815	COG0251	oxidation-reduction process
C6W73_RS21820	COG1199	ATP-dependent helicase activity
C6W73_RS21825	COG1214	PFAM Peptidase M22, glycoprotease
C6W73_RS21830	COG3065	identical protein binding
C6W73_RS21835	COG0318	PFAM AMP-dependent synthetase and ligase
C6W73_RS21840	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
C6W73_RS21845	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C6W73_RS21850	COG4638	Rieske (2fe-2S)
C6W73_RS21855	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C6W73_RS21860	COG0473	3-isopropylmalate dehydrogenase activity
C6W73_RS21865	COG0583	DNA-binding transcription factor activity
C6W73_RS21875	COG3615	Tellurite resistance protein tehB
C6W73_RS21895	COG2261	transglycosylase associated protein
C6W73_RS21910	COG2199	diguanylate cyclase activity
C6W73_RS21910	COG2203	Gaf domain
C6W73_RS21915	COG3042	response to heat
C6W73_RS21920	COG3189	MarR family transcriptional regulator
C6W73_RS21925	COG2807	transmembrane transport
C6W73_RS21930	COG2207	Transcriptional regulator
C6W73_RS21945	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C6W73_RS21950	COG2199	diguanylate cyclase activity
C6W73_RS21955	COG2199	diguanylate cyclase activity
C6W73_RS21965	COG2766	serine protein kinase
C6W73_RS21970	COG3713	MltA-interacting MipA family protein
C6W73_RS21975	COG0656	L-ascorbic acid biosynthetic process
C6W73_RS21980	COG0676	glucose-6-phosphate 1-epimerase activity
C6W73_RS21985	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C6W73_RS21995	COG3139	Protein of unknown function (DUF1315)
C6W73_RS22000	COG1063	alcohol dehydrogenase
C6W73_RS22005	COG2271	Major facilitator Superfamily
C6W73_RS22010	COG1063	alcohol dehydrogenase
C6W73_RS22015	COG0191	fructose-bisphosphate aldolase activity
C6W73_RS22020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6W73_RS22030	COG1349	DNA-binding transcription factor activity
C6W73_RS22035	COG2814	Major facilitator Superfamily
C6W73_RS22040	COG1335	isochorismatase
C6W73_RS22045	COG0252	asparaginase activity
C6W73_RS22060	COG0778	Nitroreductase
C6W73_RS22075	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C6W73_RS22085	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C6W73_RS22095	COG0494	nUDIX hydrolase
C6W73_RS22100	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C6W73_RS22105	COG2897	thiosulfate sulfurtransferase activity
C6W73_RS22110	COG4136	ATPase activity
C6W73_RS22115	COG4135	transport system, permease component
C6W73_RS22120	COG4134	Bacterial extracellular solute-binding protein
C6W73_RS22125	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C6W73_RS22130	COG0398	Pfam SNARE associated Golgi protein
C6W73_RS22140	COG0398	Pfam SNARE associated Golgi protein
C6W73_RS22145	COG0708	Exodeoxyribonuclease III
C6W73_RS22180	COG3678	ATP-independent chaperone mediated protein folding
C6W73_RS22190	COG0322	excinuclease ABC activity
C6W73_RS22200	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C6W73_RS22210	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C6W73_RS22215	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C6W73_RS22220	COG1447	Phosphotransferase system cellobiose-specific component IIA
C6W73_RS22225	COG2169	Transcriptional regulator
C6W73_RS22225	COG1917	Cupin 2, conserved barrel domain protein
C6W73_RS22230	COG1486	melibiose metabolic process
C6W73_RS22240	COG0753	catalase activity
C6W73_RS22260	COG1823	symporter activity
C6W73_RS22265	COG1988	membrane-bound metal-dependent
C6W73_RS22270	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C6W73_RS22280	COG3001	Fructosamine kinase
C6W73_RS22290	COG1105	Belongs to the carbohydrate kinase PfkB family
C6W73_RS22295	COG3137	Salt-induced outer membrane protein
C6W73_RS22355	COG0386	Belongs to the glutathione peroxidase family
C6W73_RS22365	COG0791	NLP P60 protein
C6W73_RS22370	COG2200	EAL domain
C6W73_RS22380	COG4256	Hemin uptake protein
C6W73_RS22385	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C6W73_RS22400	COG0574	Belongs to the PEP-utilizing enzyme family
C6W73_RS22400	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C6W73_RS22405	COG0318	PFAM AMP-dependent synthetase and ligase
C6W73_RS22410	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C6W73_RS22415	COG0644	oxidoreductase
C6W73_RS22420	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C6W73_RS22425	COG2086	electron transfer activity
C6W73_RS22435	COG2207	Transcriptional regulator
C6W73_RS22435	COG1917	Cupin 2, conserved barrel domain protein
C6W73_RS22440	COG1960	acyl-CoA dehydrogenase activity
C6W73_RS22445	COG4670	ketone body catabolic process
C6W73_RS22460	COG2271	Major facilitator Superfamily
C6W73_RS22465	COG0738	Major facilitator superfamily
C6W73_RS22480	COG0628	permease
C6W73_RS22490	COG0247	lactate metabolic process
C6W73_RS22490	COG0277	FAD linked oxidase domain protein
C6W73_RS22495	COG2050	protein possibly involved in aromatic compounds catabolism
C6W73_RS22505	COG0316	Belongs to the HesB IscA family
C6W73_RS22510	COG0719	Fe-S assembly protein
C6W73_RS22515	COG0396	ATPase activity
C6W73_RS22520	COG0719	Fe-S assembly protein
C6W73_RS22535	COG1376	ErfK ybiS ycfS ynhG family protein
C6W73_RS22540	COG4238	major outer membrane lipoprotein
C6W73_RS22545	COG0469	pyruvate kinase activity
C6W73_RS22555	COG0437	4 iron, 4 sulfur cluster binding
C6W73_RS22560	COG2414	aldehyde ferredoxin oxidoreductase
C6W73_RS22570	COG0437	4 iron, 4 sulfur cluster binding
C6W73_RS22575	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
C6W73_RS22585	COG4529	Protein conserved in bacteria
C6W73_RS22605	COG3468	outer membrane autotransporter barrel domain protein
C6W73_RS22615	COG0307	riboflavin synthase, alpha
C6W73_RS22620	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C6W73_RS22625	COG2814	Major facilitator Superfamily
C6W73_RS22630	COG0583	DNA-binding transcription factor activity
C6W73_RS22650	COG2814	Major facilitator Superfamily
C6W73_RS22655	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C6W73_RS22660	COG0791	NLP P60 protein
C6W73_RS22665	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C6W73_RS22670	COG1201	RNA secondary structure unwinding
C6W73_RS22680	COG0346	lactoylglutathione lyase activity
C6W73_RS22685	COG1902	pentaerythritol trinitrate reductase activity
C6W73_RS22690	COG1309	transcriptional regulator
C6W73_RS22695	COG3313	Fe-S protein
C6W73_RS22700	COG4989	oxidoreductase activity
C6W73_RS22705	COG2032	superoxide dismutase activity
C6W73_RS22710	COG1289	transmembrane transporter activity
C6W73_RS22715	COG1566	PFAM secretion protein HlyD family protein
C6W73_RS22730	COG3133	Outer membrane lipoprotein
C6W73_RS22740	COG3895	Periplasmic Protein
C6W73_RS22755	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
C6W73_RS22760	COG0625	glutathione transferase activity
C6W73_RS22765	COG3104	oligopeptide transport
C6W73_RS22775	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C6W73_RS22785	COG4659	FMN binding
C6W73_RS22830	COG0673	inositol 2-dehydrogenase activity
C6W73_RS22840	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C6W73_RS22845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6W73_RS22845	COG1263	PTS System
C6W73_RS22850	COG1609	Transcriptional regulator
C6W73_RS22855	COG1028	Short-chain dehydrogenase reductase Sdr
C6W73_RS22860	COG1309	transcriptional regulator
C6W73_RS22865	COG3250	beta-galactosidase activity
C6W73_RS22880	COG5339	Protein conserved in bacteria
C6W73_RS22885	COG1482	cell wall glycoprotein biosynthetic process
C6W73_RS22890	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C6W73_RS22890	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C6W73_RS22895	COG0114	fumarate hydratase activity
C6W73_RS22905	COG2205	protein histidine kinase activity
C6W73_RS22910	COG0745	RESPONSE REGULATOR receiver
C6W73_RS22915	COG3136	membrane protein required for alginate biosynthesis
C6W73_RS22925	COG0531	amino acid
C6W73_RS22940	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
C6W73_RS22945	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
C6W73_RS23050	COG4220	transposase activity
C6W73_RS23080	COG3591	Belongs to the peptidase S1B family
C6W73_RS23100	COG2814	Major facilitator Superfamily
C6W73_RS23105	COG0583	DNA-binding transcription factor activity
C6W73_RS23110	COG1940	carbohydrate kinase activity
C6W73_RS23115	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C6W73_RS23125	COG3381	protein complex oligomerization
C6W73_RS23130	COG3302	dmso reductase anchor subunit
C6W73_RS23135	COG0437	4 iron, 4 sulfur cluster binding
C6W73_RS23140	COG0243	molybdopterin cofactor binding
C6W73_RS23145	COG0243	molybdopterin cofactor binding
C6W73_RS23160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C6W73_RS23180	COG4948	Mandelate Racemase Muconate Lactonizing
C6W73_RS23185	COG1063	alcohol dehydrogenase
C6W73_RS23195	COG0582	viral genome integration into host DNA
C6W73_RS23205	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6W73_RS23245	COG4197	protein conserved in bacteria, prophage-related
C6W73_RS23265	COG1846	Transcriptional regulator
C6W73_RS23300	COG1403	HNH endonuclease
C6W73_RS23305	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C6W73_RS23375	COG3772	lysozyme
C6W73_RS23395	COG0582	viral genome integration into host DNA
C6W73_RS23460	COG0740	serine-type endopeptidase activity
C6W73_RS23490	COG0740	serine-type endopeptidase activity
C6W73_RS23565	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6W73_RS23575	COG0477	Major facilitator Superfamily
C6W73_RS23580	COG0246	Mannitol dehydrogenase
C6W73_RS23590	COG1802	Transcriptional regulator
C6W73_RS23595	COG4221	oxidoreductase activity
C6W73_RS23605	COG0339	signal peptide processing
C6W73_RS23615	COG1546	Belongs to the CinA family
C6W73_RS23620	COG3111	PFAM Bacterial OB fold (BOF) protein
C6W73_RS23625	COG3706	GGDEF domain
C6W73_RS23635	COG2814	Major facilitator Superfamily
C6W73_RS23640	COG0697	spore germination
C6W73_RS23645	COG2188	Transcriptional regulator
C6W73_RS23655	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C6W73_RS23660	COG1447	Phosphotransferase system cellobiose-specific component IIA
C6W73_RS23670	COG2723	6-phospho-beta-galactosidase activity
C6W73_RS23680	COG4977	sequence-specific DNA binding
C6W73_RS23685	COG1846	Transcriptional regulator
C6W73_RS23710	COG0583	DNA-binding transcription factor activity
C6W73_RS23715	COG1012	belongs to the aldehyde dehydrogenase family
C6W73_RS23720	COG2066	Belongs to the glutaminase family
C6W73_RS23735	COG2199	diguanylate cyclase activity
C6W73_RS23755	COG3781	membrane
C6W73_RS23805	COG3210	domain, Protein
C6W73_RS23805	COG2911	Protein conserved in bacteria
C6W73_RS23810	COG1396	sequence-specific DNA binding
C6W73_RS23815	COG3550	peptidyl-serine autophosphorylation
C6W73_RS23835	COG3539	Fimbrial protein
C6W73_RS23845	COG3188	usher protein
C6W73_RS23850	COG3539	Fimbrial protein
C6W73_RS23855	COG3539	Fimbrial protein
C6W73_RS23860	COG3539	Fimbrial protein
C6W73_RS23865	COG0243	molybdopterin cofactor binding
C6W73_RS23875	COG2207	Transcriptional regulator
C6W73_RS23880	COG3119	arylsulfatase activity
C6W73_RS23885	COG0641	radical SAM
C6W73_RS23890	COG4178	(ABC) transporter
C6W73_RS23895	COG4771	TonB-dependent receptor
C6W73_RS23900	COG0612	Peptidase, M16
C6W73_RS23905	COG0076	glutamate decarboxylase activity
C6W73_RS23910	COG0531	amino acid
C6W73_RS23915	COG1649	PFAM Uncharacterised BCR, COG1649
C6W73_RS23925	COG2200	EAL domain
C6W73_RS23925	COG2202	Pas domain
C6W73_RS23925	COG2199	diguanylate cyclase activity
C6W73_RS23930	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
C6W73_RS23935	COG0747	negative chemotaxis
C6W73_RS23940	COG0601	transmembrane transport
C6W73_RS23945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C6W73_RS23950	COG0444	Belongs to the ABC transporter superfamily
C6W73_RS23955	COG4608	Belongs to the ABC transporter superfamily
C6W73_RS23960	COG1764	response to oxidative stress
C6W73_RS23985	COG1064	alcohol dehydrogenase
C6W73_RS23990	COG3093	addiction module antidote protein HigA
C6W73_RS23995	COG2864	formate dehydrogenase
C6W73_RS24000	COG0437	4 iron, 4 sulfur cluster binding
C6W73_RS24010	COG0697	spore germination
C6W73_RS24015	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C6W73_RS24020	COG4886	Leucine-rich repeat (LRR) protein
C6W73_RS24025	COG2223	nitrite transmembrane transporter activity
C6W73_RS24030	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C6W73_RS24035	COG1140	nitrate reductase beta subunit
C6W73_RS24040	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C6W73_RS24045	COG2181	nitrate reductase activity
C6W73_RS24050	COG0384	phenazine biosynthesis protein PhzF
C6W73_RS24055	COG2162	N-hydroxyarylamine O-acetyltransferase activity
C6W73_RS24060	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C6W73_RS24090	COG3209	COG3209 Rhs family protein
C6W73_RS24105	COG0625	glutathione transferase activity
C6W73_RS24110	COG1113	amino acid transport
C6W73_RS24115	COG3391	amine dehydrogenase activity
C6W73_RS24125	COG4772	TonB-dependent receptor
C6W73_RS24130	COG1802	Transcriptional regulator
C6W73_RS24135	COG2130	NADP-dependent
C6W73_RS24145	COG1247	-acetyltransferase
C6W73_RS24150	COG3238	Protein conserved in bacteria
C6W73_RS24180	COG1177	transmembrane transport
C6W73_RS24185	COG1176	ABC-type spermidine putrescine transport system, permease component I
C6W73_RS24190	COG3842	ATPase activity
C6W73_RS24195	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C6W73_RS24200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C6W73_RS24205	COG1598	PFAM Uncharacterised protein family UPF0150
C6W73_RS24220	COG0826	peptidase U32
C6W73_RS24225	COG1396	sequence-specific DNA binding
C6W73_RS24230	COG3135	benzoate transporter
C6W73_RS24235	COG0675	Transposase, IS605 OrfB family
C6W73_RS24250	COG0500	methyltransferase
C6W73_RS24255	COG1275	C4-dicarboxylate transporter malic acid transport protein
C6W73_RS24260	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C6W73_RS24265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C6W73_RS24270	COG2841	Protein conserved in bacteria
C6W73_RS24290	COG5383	Protein conserved in bacteria
C6W73_RS24295	COG0583	DNA-binding transcription factor activity
C6W73_RS24300	COG0840	transmembrane signaling receptor activity
C6W73_RS24315	COG3038	cytochrome b561
C6W73_RS24320	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C6W73_RS24325	COG1012	belongs to the aldehyde dehydrogenase family
C6W73_RS24330	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C6W73_RS24335	COG1643	Atp-dependent helicase
C6W73_RS24345	COG2453	phosphatase
C6W73_RS24345	COG0671	phosphoesterase, PA-phosphatase related
C6W73_RS24350	COG2267	carboxylic ester hydrolase activity
C6W73_RS24355	COG4589	Belongs to the CDS family
C6W73_RS24360	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C6W73_RS24370	COG0667	Aldo Keto reductase
C6W73_RS24375	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C6W73_RS24380	COG3327	negative regulation of DNA-templated transcription, initiation
C6W73_RS24385	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
C6W73_RS24390	COG0183	Belongs to the thiolase family
C6W73_RS24395	COG2050	protein possibly involved in aromatic compounds catabolism
C6W73_RS24400	COG1250	3-hydroxyacyl-CoA dehydrogenase
C6W73_RS24405	COG1024	Enoyl-CoA hydratase
C6W73_RS24410	COG1024	Enoyl-CoA hydratase
C6W73_RS24415	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C6W73_RS24420	COG2151	metal-sulfur cluster biosynthetic enzyme
C6W73_RS24425	COG3396	Phenylacetate-CoA oxygenase
C6W73_RS24430	COG3460	Phenylacetate-CoA oxygenase
C6W73_RS24435	COG3396	Phenylacetate-CoA oxygenase
C6W73_RS24440	COG1012	belongs to the aldehyde dehydrogenase family
C6W73_RS24440	COG2030	dehydratase
C6W73_RS24445	COG3733	amine oxidase
C6W73_RS24450	COG1012	belongs to the aldehyde dehydrogenase family
C6W73_RS24455	COG2207	Transcriptional regulator
C6W73_RS24460	COG3784	Protein of unknown function (DUF1318)
C6W73_RS24470	COG2911	Protein conserved in bacteria
C6W73_RS24475	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C6W73_RS24480	COG3187	Heat shock protein
C6W73_RS24485	COG3042	response to heat
C6W73_RS24490	COG0674	pyruvate-flavodoxin oxidoreductase activity
C6W73_RS24490	COG1013	pyruvate-flavodoxin oxidoreductase activity
C6W73_RS24490	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
C6W73_RS24490	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C6W73_RS24495	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C6W73_RS24500	COG0589	response to stress
C6W73_RS24510	COG0513	Belongs to the DEAD box helicase family
C6W73_RS24525	COG3706	GGDEF domain
C6W73_RS24530	COG2840	Smr protein MutS2
C6W73_RS24540	COG0583	DNA-binding transcription factor activity
C6W73_RS24545	COG1473	amidohydrolase
C6W73_RS24550	COG1473	amidohydrolase
C6W73_RS24560	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
C6W73_RS24565	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C6W73_RS24570	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C6W73_RS24575	COG0589	response to stress
C6W73_RS24580	COG3182	Iron-regulated membrane protein
C6W73_RS24585	COG0668	transmembrane transport
C6W73_RS24590	COG4166	transmembrane transport
C6W73_RS24595	COG0583	DNA-binding transcription factor activity
C6W73_RS24600	COG1073	alpha beta
C6W73_RS24605	COG1073	alpha beta
C6W73_RS24610	COG0702	epimerase
C6W73_RS24615	COG2866	Carboxypeptidase
C6W73_RS24620	COG4948	Mandelate Racemase Muconate Lactonizing
C6W73_RS24625	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
C6W73_RS24630	COG3283	Transcriptional regulator of aromatic amino acids metabolism
C6W73_RS24640	COG3106	COG3106 Predicted ATPase
C6W73_RS24645	COG1609	Transcriptional regulator
C6W73_RS24655	COG3842	ATPase activity
C6W73_RS24660	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C6W73_RS24665	COG1554	hydrolase, family 65, central catalytic
C6W73_RS24670	COG0673	inositol 2-dehydrogenase activity
C6W73_RS24675	COG1082	Xylose isomerase domain protein TIM barrel
C6W73_RS24680	COG1063	alcohol dehydrogenase
C6W73_RS24685	COG0395	ABC-type sugar transport system, permease component
C6W73_RS24690	COG1175	transmembrane transport
C6W73_RS24695	COG1653	transport
C6W73_RS24700	COG0366	Alpha amylase catalytic
C6W73_RS24705	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C6W73_RS24715	COG1983	PspC domain protein
C6W73_RS24725	COG1842	Phage shock protein A
C6W73_RS24730	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C6W73_RS24735	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C6W73_RS24740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C6W73_RS24745	COG1012	belongs to the aldehyde dehydrogenase family
C6W73_RS24755	COG1917	Cupin 2, conserved barrel domain protein
C6W73_RS24755	COG1396	sequence-specific DNA binding
C6W73_RS24760	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C6W73_RS24765	COG0174	glutamine synthetase
C6W73_RS24770	COG0531	amino acid
C6W73_RS24785	COG4166	transmembrane transport
C6W73_RS24790	COG4168	peptide transport system, permease
C6W73_RS24795	COG4171	peptide transport system, permease
C6W73_RS24800	COG4172	Belongs to the ABC transporter superfamily
C6W73_RS24805	COG4172	Belongs to the ABC transporter superfamily
C6W73_RS24810	COG2852	Protein conserved in bacteria
C6W73_RS24815	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C6W73_RS24820	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C6W73_RS24820	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C6W73_RS24835	COG5001	Diguanylate cyclase
C6W73_RS24845	COG1349	DNA-binding transcription factor activity
C6W73_RS24855	COG0023	Translation Initiation Factor
C6W73_RS24865	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
C6W73_RS24870	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
C6W73_RS24875	COG0671	phosphoesterase, PA-phosphatase related
C6W73_RS24885	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C6W73_RS24905	COG0583	DNA-binding transcription factor activity
C6W73_RS24915	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C6W73_RS24930	COG0616	signal peptide processing
C6W73_RS24935	COG1028	Short-chain dehydrogenase reductase Sdr
C6W73_RS24940	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
C6W73_RS24945	COG1187	pseudouridine synthase activity
C6W73_RS24950	COG0009	L-threonylcarbamoyladenylate synthase
C6W73_RS24955	COG0613	PHP domain protein
C6W73_RS24965	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C6W73_RS24970	COG0512	Glutamine amidotransferase of anthranilate synthase
C6W73_RS24970	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C6W73_RS24975	COG0134	indole-3-glycerol-phosphate synthase activity
C6W73_RS24975	COG0135	phosphoribosylanthranilate isomerase activity
C6W73_RS24990	COG3729	General stress protein
C6W73_RS24995	COG3685	Protein conserved in bacteria
C6W73_RS25000	COG3685	Protein conserved in bacteria
C6W73_RS25025	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6W73_RS25025	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6W73_RS25150	COG3646	Phage regulatory protein
C6W73_RS25165	COG3772	lysozyme
C6W73_RS25205	COG2207	Transcriptional regulator
C6W73_RS25215	COG3064	Membrane
C6W73_RS25250	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C6W73_RS25255	COG1403	HNH endonuclease
C6W73_RS25300	COG1846	Transcriptional regulator
C6W73_RS25305	COG1484	DNA-dependent DNA replication
C6W73_RS25310	COG1846	Transcriptional regulator
C6W73_RS25325	COG1396	sequence-specific DNA binding
C6W73_RS25360	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6W73_RS25370	COG0582	viral genome integration into host DNA
C6W73_RS25375	COG3047	cAMP biosynthetic process
C6W73_RS25395	COG1607	acyl-coa hydrolase
C6W73_RS25405	COG2350	Protein conserved in bacteria
C6W73_RS25410	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C6W73_RS25430	COG4608	Belongs to the ABC transporter superfamily
C6W73_RS25435	COG0444	Belongs to the ABC transporter superfamily
C6W73_RS25440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C6W73_RS25445	COG0601	transmembrane transport
C6W73_RS25450	COG4166	transmembrane transport
C6W73_RS25460	COG2095	MarC family integral membrane protein
C6W73_RS25465	COG1012	belongs to the aldehyde dehydrogenase family
C6W73_RS25465	COG1454	alcohol dehydrogenase
C6W73_RS25475	COG1435	thymidine kinase activity
C6W73_RS25485	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C6W73_RS25490	COG0745	RESPONSE REGULATOR receiver
C6W73_RS25495	COG1752	Esterase of the alpha-beta hydrolase superfamily
C6W73_RS25505	COG0788	formyltetrahydrofolate deformylase activity
C6W73_RS25525	COG2181	nitrate reductase activity
C6W73_RS25530	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C6W73_RS25535	COG1140	nitrate reductase beta subunit
C6W73_RS25540	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C6W73_RS25545	COG2223	nitrite transmembrane transporter activity
C6W73_RS25555	COG3850	Histidine kinase
C6W73_RS25560	COG2197	response regulator
C6W73_RS25565	COG4932	domain protein
C6W73_RS25570	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
C6W73_RS25575	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
C6W73_RS25580	COG4572	Cation transport regulator
C6W73_RS25585	COG0387	Pfam Sodium calcium exchanger
C6W73_RS25610	COG2912	Transglutaminase-like superfamily
C6W73_RS25615	COG3094	Invasion gene expression up-regulator, SirB
C6W73_RS25620	COG2890	protein-(glutamine-N5) methyltransferase activity
C6W73_RS25650	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C6W73_RS25660	COG0659	secondary active sulfate transmembrane transporter activity
C6W73_RS25675	COG0012	GTP binding
C6W73_RS25690	COG3468	outer membrane autotransporter barrel domain protein
C6W73_RS25695	COG3284	Transcriptional regulator
C6W73_RS25700	COG2376	Dihydroxyacetone kinase
C6W73_RS25705	COG1461	Dihydroxyacetone kinase
C6W73_RS25710	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
C6W73_RS25710	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6W73_RS25710	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C6W73_RS25735	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
C6W73_RS25750	COG1619	proteins homologs of microcin C7 resistance protein MccF
C6W73_RS25765	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C6W73_RS25775	COG2719	SpoVR family
C6W73_RS25790	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C6W73_RS25795	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C6W73_RS25800	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C6W73_RS25815	COG0179	Fumarylacetoacetate (FAA) hydrolase
C6W73_RS25845	COG2894	cell division
C6W73_RS25905	COG2200	EAL domain
C6W73_RS25930	COG2200	EAL domain
C6W73_RS25935	COG0789	Transcriptional regulator
C6W73_RS25940	COG5562	phage envelope protein
C6W73_RS25950	COG0538	isocitrate dehydrogenase activity
C6W73_RS25955	COG1187	pseudouridine synthase activity
C6W73_RS25975	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C6W73_RS25985	COG2205	protein histidine kinase activity
C6W73_RS25995	COG1802	Transcriptional regulator
C6W73_RS25995	COG4626	Terminase
C6W73_RS26115	COG2850	peptidyl-arginine hydroxylation
C6W73_RS26130	COG3842	ATPase activity
C6W73_RS26140	COG0727	PFAM Uncharacterised protein family (UPF0153)
C6W73_RS26155	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6W73_RS26300	COG3772	lysozyme
C6W73_RS26425	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C6W73_RS26620	COG3736	Type IV secretory pathway, component VirB8
C6W73_RS26640	COG1585	Membrane protein implicated in regulation of membrane protease activity
C6W73_RS26825	COG4771	TonB-dependent receptor
C6W73_RS26875	COG3468	outer membrane autotransporter barrel domain protein
C6W73_RS26905	COG2801	Transposase and inactivated derivatives
C6W73_RS26915	COG1556	Lactate utilization protein
C6W73_RS26920	COG1139	Iron-sulfur cluster binding protein
C6W73_RS26925	COG0247	lactate metabolic process
C6W73_RS26930	COG1620	l-lactate permease
C6W73_RS26980	COG5295	Hep Hag repeat protein
C6W73_RS27005	COG2274	protein secretion by the type I secretion system
C6W73_RS27145	COG4372	Transposase
C6W73_RS27150	COG3436	PFAM IS66 Orf2 family protein
C6W73_RS27170	COG4771	TonB-dependent receptor
C6W73_RS27225	COG1192	Involved in chromosome partitioning
C6W73_RS27495	COG2194	sulfuric ester hydrolase activity
C6W73_RS27510	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C6W73_RS27610	COG2805	Type II/IV secretion system protein
C6W73_RS27665	COG0741	lytic transglycosylase activity
C6W73_RS27680	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C6W73_RS27720	COG2268	Band 7 protein