locus-tag	class	description
ND05_RS00030	COG4372	Transposase
ND05_RS00055	COG4372	Transposase
ND05_RS00060	COG3436	PFAM IS66 Orf2 family protein
ND05_RS00190	COG2274	protein secretion by the type I secretion system
ND05_RS00215	COG0726	polysaccharide deacetylase
ND05_RS00220	COG0297	glycogen (starch) synthase activity
ND05_RS00230	COG1560	Kdo2-lipid A biosynthetic process
ND05_RS00240	COG4372	Transposase
ND05_RS00245	COG3436	PFAM IS66 Orf2 family protein
ND05_RS00365	COG1585	Membrane protein implicated in regulation of membrane protease activity
ND05_RS00380	COG3468	outer membrane autotransporter barrel domain protein
ND05_RS00480	COG3436	PFAM IS66 Orf2 family protein
ND05_RS00485	COG4372	Transposase
ND05_RS00580	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ND05_RS00585	COG2146	nitrite reductase [NAD(P)H] activity
ND05_RS00590	COG2116	formate transmembrane transporter activity
ND05_RS00615	COG0531	amino acid
ND05_RS00620	COG2222	sugar isomerase
ND05_RS00630	COG1082	Xylose isomerase domain protein TIM barrel
ND05_RS00640	COG2188	Transcriptional regulator
ND05_RS00660	COG1735	metal-dependent hydrolase with the TIM-barrel fold
ND05_RS00665	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
ND05_RS00670	COG3457	Alanine racemase
ND05_RS00680	COG2188	Transcriptional regulator
ND05_RS00685	COG0180	Tryptophanyl-tRNA synthetase
ND05_RS00695	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ND05_RS00700	COG0338	D12 class N6 adenine-specific DNA methyltransferase
ND05_RS00705	COG3266	domain, Protein
ND05_RS00725	COG4796	Type ii and iii secretion system protein
ND05_RS00740	COG3166	PFAM Fimbrial assembly family protein
ND05_RS00745	COG4972	Pilus assembly protein
ND05_RS00750	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ND05_RS00755	COG0494	nUDIX hydrolase
ND05_RS00765	COG1011	Hydrolase
ND05_RS00770	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ND05_RS00780	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
ND05_RS00810	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ND05_RS00815	COG2183	response to ionizing radiation
ND05_RS00825	COG1918	ferrous iron import across plasma membrane
ND05_RS00830	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ND05_RS00845	COG5464	transposase or invertase
ND05_RS00865	COG2610	gluconate transmembrane transporter activity
ND05_RS00870	COG1640	4-alpha-glucanotransferase
ND05_RS00875	COG0058	SHG alpha-glucan phosphorylase activity
ND05_RS00890	COG1690	Belongs to the RtcB family
ND05_RS00895	COG4650	regulator
ND05_RS00900	COG1349	DNA-binding transcription factor activity
ND05_RS00915	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ND05_RS00940	COG0058	SHG alpha-glucan phosphorylase activity
ND05_RS00965	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ND05_RS00970	COG2095	MarC family integral membrane protein
ND05_RS00975	COG2610	gluconate transmembrane transporter activity
ND05_RS00980	COG3265	gluconokinase activity
ND05_RS00985	COG1609	Transcriptional regulator
ND05_RS00990	COG1741	Belongs to the pirin family
ND05_RS00995	COG0673	inositol 2-dehydrogenase activity
ND05_RS01005	COG1247	-acetyltransferase
ND05_RS01010	COG3157	Type VI secretion system effector, Hcp
ND05_RS01030	COG0405	Gamma-glutamyltransferase
ND05_RS01040	COG0584	glycerophosphoryl diester phosphodiesterase
ND05_RS01045	COG3842	ATPase activity
ND05_RS01050	COG0395	ABC-type sugar transport system, permease component
ND05_RS01055	COG1175	transmembrane transport
ND05_RS01060	COG1653	transport
ND05_RS01070	COG0411	ABC transporter
ND05_RS01075	COG4177	L-phenylalanine transmembrane transporter activity
ND05_RS01080	COG0559	Belongs to the binding-protein-dependent transport system permease family
ND05_RS01085	COG0683	leucine binding
ND05_RS01090	COG0456	acetyltransferase
ND05_RS01095	COG0683	leucine binding
ND05_RS01100	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ND05_RS01105	COG2177	Part of the ABC transporter FtsEX involved in
ND05_RS01110	COG2884	Cell division ATP-binding protein ftsE
ND05_RS01115	COG0552	protein localization to endoplasmic reticulum
ND05_RS01120	COG0742	ribosomal rna small subunit methyltransferase
ND05_RS01125	COG3776	membrane
ND05_RS01135	COG3714	YhhN family
ND05_RS01150	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ND05_RS01165	COG0628	permease
ND05_RS01170	COG2091	lysine biosynthetic process via aminoadipic acid
ND05_RS01175	COG0747	negative chemotaxis
ND05_RS01180	COG0601	transmembrane transport
ND05_RS01185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ND05_RS01190	COG0444	Belongs to the ABC transporter superfamily
ND05_RS01215	COG0842	Transport permease protein
ND05_RS01220	COG0842	Transport permease protein
ND05_RS01220	COG1129	ABC transporter
ND05_RS01225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ND05_RS01250	COG2081	HI0933 family
ND05_RS01255	COG0306	phosphate transporter
ND05_RS01265	COG0589	response to stress
ND05_RS01275	COG3104	oligopeptide transport
ND05_RS01285	COG0339	signal peptide processing
ND05_RS01290	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ND05_RS01295	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ND05_RS01310	COG0640	Transcriptional regulator
ND05_RS01315	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ND05_RS01320	COG1393	Belongs to the ArsC family
ND05_RS01340	COG3065	identical protein binding
ND05_RS01350	COG2197	response regulator
ND05_RS01355	COG1285	pathogenesis
ND05_RS01370	COG3247	response to pH
ND05_RS01375	COG2771	luxR family
ND05_RS01385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ND05_RS01390	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ND05_RS01400	COG2207	Transcriptional regulator
ND05_RS01410	COG0076	glutamate decarboxylase activity
ND05_RS01415	COG1858	cytochrome C peroxidase
ND05_RS01425	COG2197	response regulator
ND05_RS01430	COG0583	DNA-binding transcription factor activity
ND05_RS01435	COG1295	ribonuclease BN
ND05_RS01440	COG0477	Major facilitator Superfamily
ND05_RS01445	COG2982	Protein involved in outer membrane biogenesis
ND05_RS01450	COG2200	EAL domain
ND05_RS01465	COG0612	Peptidase, M16
ND05_RS01480	COG2200	EAL domain
ND05_RS01480	COG2199	diguanylate cyclase activity
ND05_RS01485	COG0457	Tetratricopeptide repeat
ND05_RS01485	COG3118	belongs to the thioredoxin family
ND05_RS01490	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
ND05_RS01495	COG1215	transferase activity, transferring glycosyl groups
ND05_RS01500	COG1215	transferase activity, transferring glycosyl groups
ND05_RS01525	COG2194	sulfuric ester hydrolase activity
ND05_RS01555	COG0814	amino acid
ND05_RS01560	COG4608	Belongs to the ABC transporter superfamily
ND05_RS01565	COG0444	Belongs to the ABC transporter superfamily
ND05_RS01570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ND05_RS01575	COG0601	transmembrane transport
ND05_RS01585	COG0747	negative chemotaxis
ND05_RS01600	COG2194	sulfuric ester hydrolase activity
ND05_RS01605	COG2223	nitrite transmembrane transporter activity
ND05_RS01615	COG5571	outer membrane autotransporter
ND05_RS01620	COG2818	Glycosylase
ND05_RS01625	COG0456	acetyltransferase
ND05_RS01630	COG0243	molybdopterin cofactor binding
ND05_RS01635	COG2885	chlorophyll binding
ND05_RS01650	COG2944	sequence-specific DNA binding
ND05_RS01655	COG1278	Cold shock
ND05_RS01680	COG3274	enterobacterial common antigen metabolic process
ND05_RS01685	COG4682	membrane
ND05_RS01690	COG4682	membrane
ND05_RS01695	COG1070	Carbohydrate kinase
ND05_RS01705	COG4213	ABC transporter substrate-binding protein
ND05_RS01715	COG4214	carbohydrate transport
ND05_RS01720	COG2207	Transcriptional regulator
ND05_RS01720	COG1609	Transcriptional regulator
ND05_RS01725	COG2992	FlgJ-related protein
ND05_RS01730	COG0366	Alpha amylase catalytic
ND05_RS01735	COG3977	Valine--pyruvate aminotransferase
ND05_RS01740	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ND05_RS01745	COG1414	Transcriptional regulator
ND05_RS01755	COG2731	YhcH YjgK YiaL family protein
ND05_RS01760	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ND05_RS01765	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ND05_RS01770	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ND05_RS01775	COG1070	Carbohydrate kinase
ND05_RS01780	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ND05_RS01785	COG3623	hexulose-6-phosphate isomerase
ND05_RS01790	COG0235	Class ii aldolase
ND05_RS01800	COG3713	MltA-interacting MipA family protein
ND05_RS01805	COG0583	DNA-binding transcription factor activity
ND05_RS01810	COG1566	PFAM secretion protein HlyD family protein
ND05_RS01825	COG1012	belongs to the aldehyde dehydrogenase family
ND05_RS01830	COG1454	alcohol dehydrogenase
ND05_RS01835	COG3276	selenocysteine insertion sequence binding
ND05_RS01845	COG0625	glutathione transferase activity
ND05_RS01850	COG3209	COG3209 Rhs family protein
ND05_RS01860	COG3209	COG3209 Rhs family protein
ND05_RS01865	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ND05_RS01885	COG1566	PFAM secretion protein HlyD family protein
ND05_RS01895	COG2213	PTS system mannitol-specific
ND05_RS01895	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ND05_RS01905	COG3722	fumarate hydratase activity
ND05_RS01930	COG5295	Hep Hag repeat protein
ND05_RS01940	COG1620	l-lactate permease
ND05_RS01945	COG2186	Transcriptional regulator
ND05_RS01950	COG2186	Transcriptional regulator
ND05_RS01960	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ND05_RS01965	COG1045	serine acetyltransferase
ND05_RS01980	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ND05_RS01985	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ND05_RS02000	COG4942	peptidase
ND05_RS02005	COG2861	carbohydrate metabolic process
ND05_RS02010	COG1216	Glycosyl transferase, family 2
ND05_RS02020	COG0156	8-amino-7-oxononanoate synthase activity
ND05_RS02030	COG0859	PFAM glycosyl transferase family 9
ND05_RS02035	COG0859	PFAM glycosyl transferase family 9
ND05_RS02040	COG3307	-O-antigen
ND05_RS02045	COG1216	Glycosyl transferase, family 2
ND05_RS02050	COG1442	glycosyl transferase family 8
ND05_RS02055	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ND05_RS02070	COG0515	serine threonine protein kinase
ND05_RS02075	COG0438	transferase activity, transferring glycosyl groups
ND05_RS02080	COG0859	PFAM glycosyl transferase family 9
ND05_RS02085	COG1519	Transferase
ND05_RS02115	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ND05_RS02145	COG1561	YicC-like family, N-terminal region
ND05_RS02150	COG3645	SOS response
ND05_RS02155	COG2860	membrane
ND05_RS02165	COG0194	GDP metabolic process
ND05_RS02175	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ND05_RS02180	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ND05_RS02185	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ND05_RS02195	COG0786	glutamate:sodium symporter activity
ND05_RS02200	COG2233	PERMEase
ND05_RS02205	COG2982	Protein involved in outer membrane biogenesis
ND05_RS02210	COG1501	Belongs to the glycosyl hydrolase 31 family
ND05_RS02215	COG2211	Major facilitator Superfamily
ND05_RS02230	COG2814	Major facilitator Superfamily
ND05_RS02235	COG0697	spore germination
ND05_RS02240	COG1464	Belongs to the NlpA lipoprotein family
ND05_RS02270	COG2252	PERMEase
ND05_RS02280	COG2271	Major facilitator Superfamily
ND05_RS02285	COG2271	Major facilitator Superfamily
ND05_RS02290	COG3851	Histidine kinase
ND05_RS02295	COG2197	response regulator
ND05_RS02300	COG0440	acetolactate synthase activity
ND05_RS02305	COG0028	Belongs to the TPP enzyme family
ND05_RS02340	COG2814	Major facilitator Superfamily
ND05_RS02345	COG0641	radical SAM
ND05_RS02355	COG2149	membrane
ND05_RS02365	COG3119	arylsulfatase activity
ND05_RS02370	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ND05_RS02375	COG2207	Transcriptional regulator
ND05_RS02390	COG2188	Transcriptional regulator
ND05_RS02410	COG5645	(Lipo)protein
ND05_RS02415	COG0823	Involved in the tonB-independent uptake of proteins
ND05_RS02425	COG2271	Major facilitator Superfamily
ND05_RS02435	COG0800	Aldolase
ND05_RS02440	COG3734	2-keto-3-deoxy-galactonokinase
ND05_RS02445	COG2186	Transcriptional regulator
ND05_RS02455	COG0561	phosphatase activity
ND05_RS02460	COG3753	Protein conserved in bacteria
ND05_RS02465	COG0187	DNA topoisomerase II activity
ND05_RS02475	COG0592	DNA-directed DNA polymerase activity
ND05_RS02525	COG0814	amino acid
ND05_RS02540	COG2091	lysine biosynthetic process via aminoadipic acid
ND05_RS02545	COG0431	NADPH-dependent FMN reductase
ND05_RS02550	COG2252	PERMEase
ND05_RS02555	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ND05_RS02575	COG3436	PFAM IS66 Orf2 family protein
ND05_RS02580	COG4372	Transposase
ND05_RS02590	COG0363	glucosamine-6-phosphate deaminase activity
ND05_RS02595	COG2382	esterase
ND05_RS02605	COG2723	6-phospho-beta-galactosidase activity
ND05_RS02615	COG3711	transcriptional antiterminator
ND05_RS02620	COG0704	Plays a role in the regulation of phosphate uptake
ND05_RS02625	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ND05_RS02630	COG0581	inorganic phosphate transmembrane transporter activity
ND05_RS02635	COG0573	inorganic phosphate transmembrane transporter activity
ND05_RS02640	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ND05_RS02665	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ND05_RS02720	COG3312	ion transport
ND05_RS02735	COG0716	FMN binding
ND05_RS02740	COG1522	sequence-specific DNA binding
ND05_RS02770	COG1129	ABC transporter
ND05_RS02775	COG1172	Belongs to the binding-protein-dependent transport system permease family
ND05_RS02780	COG1879	ABC-type sugar transport system periplasmic component
ND05_RS02785	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ND05_RS02790	COG1609	Transcriptional regulator
ND05_RS02795	COG0477	Major facilitator Superfamily
ND05_RS02800	COG2186	Transcriptional regulator
ND05_RS02840	COG3085	chromosome segregation
ND05_RS02870	COG3978	acetolactate synthase activity
ND05_RS02875	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ND05_RS02885	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ND05_RS02890	COG0583	DNA-binding transcription factor activity
ND05_RS02900	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ND05_RS02905	COG3692	DNA binding
ND05_RS02910	COG0210	DNA helicase
ND05_RS02930	COG3118	belongs to the thioredoxin family
ND05_RS02940	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ND05_RS02950	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ND05_RS02955	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
ND05_RS02960	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ND05_RS02965	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ND05_RS02970	COG1088	dTDP-glucose 4,6-dehydratase activity
ND05_RS02975	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ND05_RS02980	COG0456	acetyltransferase
ND05_RS02985	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ND05_RS02990	COG2244	polysaccharide biosynthetic process
ND05_RS03010	COG1113	amino acid transport
ND05_RS03035	COG0641	radical SAM
ND05_RS03040	COG3071	HemY protein
ND05_RS03045	COG2959	enzyme of heme biosynthesis
ND05_RS03050	COG1587	Uroporphyrinogen-III synthase
ND05_RS03065	COG3072	Adenylate cyclase
ND05_RS03075	COG5567	small periplasmic lipoprotein
ND05_RS03085	COG3159	Protein conserved in bacteria
ND05_RS03095	COG1011	Hydrolase
ND05_RS03100	COG0210	DNA helicase
ND05_RS03105	COG3698	Phosphodiester glycosidase
ND05_RS03110	COG0598	Magnesium transport protein CorA
ND05_RS03140	COG2962	Rard protein
ND05_RS03145	COG2050	protein possibly involved in aromatic compounds catabolism
ND05_RS03150	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
ND05_RS03155	COG0514	ATP-dependent DNA helicase (RecQ)
ND05_RS03160	COG1280	lysine exporter protein (LysE YggA)
ND05_RS03165	COG1280	lysine exporter protein (LysE YggA)
ND05_RS03170	COG2267	carboxylic ester hydrolase activity
ND05_RS03175	COG0561	phosphatase activity
ND05_RS03180	COG0697	spore germination
ND05_RS03185	COG0583	DNA-binding transcription factor activity
ND05_RS03205	COG0412	Dienelactone hydrolase
ND05_RS03210	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
ND05_RS03215	COG1322	Protein conserved in bacteria
ND05_RS03225	COG3165	ubiquinone biosynthetic process from chorismate
ND05_RS03235	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ND05_RS03240	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ND05_RS03245	COG0805	protein transport
ND05_RS03255	COG0250	Participates in transcription elongation, termination and antitermination
ND05_RS03260	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ND05_RS03265	COG0543	2 iron, 2 sulfur cluster binding
ND05_RS03285	COG1739	Uncharacterized protein family UPF0029
ND05_RS03290	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ND05_RS03295	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
ND05_RS03325	COG1763	Mo-molybdopterin cofactor biosynthetic process
ND05_RS03330	COG0746	molybdenum cofactor guanylyltransferase activity
ND05_RS03335	COG3084	Protein conserved in bacteria
ND05_RS03340	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ND05_RS03345	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ND05_RS03350	COG5339	Protein conserved in bacteria
ND05_RS03355	COG0204	Acyl-transferase
ND05_RS03365	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ND05_RS03365	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ND05_RS03380	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ND05_RS03390	COG2204	response regulator
ND05_RS03395	COG3852	Histidine kinase
ND05_RS03400	COG0174	glutamine synthetase
ND05_RS03410	COG1217	gtp-binding protein TYPA
ND05_RS03415	COG1349	DNA-binding transcription factor activity
ND05_RS03420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ND05_RS03430	COG3684	Belongs to the aldolase LacD family
ND05_RS03435	COG1063	alcohol dehydrogenase
ND05_RS03445	COG0477	Major facilitator Superfamily
ND05_RS03455	COG1011	Hydrolase
ND05_RS03470	COG0456	acetyltransferase
ND05_RS03495	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
ND05_RS03510	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ND05_RS03515	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ND05_RS03525	COG2864	formate dehydrogenase
ND05_RS03530	COG0437	4 iron, 4 sulfur cluster binding
ND05_RS03555	COG3711	transcriptional antiterminator
ND05_RS03555	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ND05_RS03560	COG1363	Peptidase, m42
ND05_RS03565	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ND05_RS03565	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ND05_RS03570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ND05_RS03610	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ND05_RS03630	COG2258	MOSC domain
ND05_RS03635	COG2205	protein histidine kinase activity
ND05_RS03640	COG0745	RESPONSE REGULATOR receiver
ND05_RS03645	COG3678	ATP-independent chaperone mediated protein folding
ND05_RS03660	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ND05_RS03680	COG3152	Membrane
ND05_RS03685	COG3691	Protein conserved in bacteria
ND05_RS03690	COG0589	response to stress
ND05_RS03700	COG1494	fructose-1,6-bisphosphatase
ND05_RS03710	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ND05_RS03725	COG1575	Belongs to the MenA family. Type 1 subfamily
ND05_RS03740	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ND05_RS03745	COG1609	Transcriptional regulator
ND05_RS03750	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ND05_RS03760	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
ND05_RS03770	COG0626	cystathionine gamma-synthase activity
ND05_RS03775	COG0460	homoserine dehydrogenase
ND05_RS03775	COG0527	aspartate kinase activity
ND05_RS03780	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ND05_RS03790	COG0697	spore germination
ND05_RS03795	COG3738	Protein conserved in bacteria
ND05_RS03800	COG0371	Dehydrogenase
ND05_RS03805	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ND05_RS03810	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ND05_RS03810	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ND05_RS03810	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ND05_RS03815	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ND05_RS03820	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ND05_RS03825	COG1882	Formate acetyltransferase
ND05_RS03830	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ND05_RS03835	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ND05_RS03840	COG2207	Transcriptional regulator
ND05_RS03845	COG2194	sulfuric ester hydrolase activity
ND05_RS03860	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ND05_RS03875	COG0583	DNA-binding transcription factor activity
ND05_RS03935	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ND05_RS03935	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ND05_RS03980	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ND05_RS03985	COG0250	Participates in transcription elongation, termination and antitermination
ND05_RS04030	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ND05_RS04040	COG2104	thiamine diphosphate biosynthetic process
ND05_RS04045	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ND05_RS04085	COG3068	Protein conserved in bacteria
ND05_RS04100	COG3678	ATP-independent chaperone mediated protein folding
ND05_RS04110	COG4191	Histidine kinase
ND05_RS04115	COG2204	response regulator
ND05_RS04120	COG0151	Belongs to the GarS family
ND05_RS04155	COG0456	acetyltransferase
ND05_RS04170	COG2224	Isocitrate lyase
ND05_RS04185	COG1414	Transcriptional regulator
ND05_RS04190	COG0646	methionine synthase
ND05_RS04190	COG1410	methionine synthase
ND05_RS04195	COG1283	sodium-dependent phosphate transmembrane transporter activity
ND05_RS04240	COG1187	pseudouridine synthase activity
ND05_RS04250	COG0527	aspartate kinase activity
ND05_RS04285	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ND05_RS04300	COG0477	Major facilitator Superfamily
ND05_RS04300	COG2814	Major facilitator Superfamily
ND05_RS04305	COG3833	ABC-type maltose transport systems, permease component
ND05_RS04310	COG1175	transmembrane transport
ND05_RS04315	COG2182	Extracellular solute-binding protein
ND05_RS04325	COG3842	ATPase activity
ND05_RS04370	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ND05_RS04380	COG0534	Mate efflux family protein
ND05_RS04385	COG3237	CsbD-like
ND05_RS04390	COG0735	belongs to the Fur family
ND05_RS04400	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ND05_RS04455	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
ND05_RS04505	COG3646	Phage regulatory protein
ND05_RS04525	COG1484	DNA-dependent DNA replication
ND05_RS04530	COG0305	Participates in initiation and elongation during chromosome replication
ND05_RS04540	COG1403	HNH endonuclease
ND05_RS04605	COG3772	lysozyme
ND05_RS04640	COG4220	transposase activity
ND05_RS04660	COG1030	water channel activity
ND05_RS04745	COG5301	cellulose 1,4-beta-cellobiosidase activity
ND05_RS04805	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ND05_RS04820	COG0305	Participates in initiation and elongation during chromosome replication
ND05_RS04825	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ND05_RS04830	COG1448	Aminotransferase
ND05_RS04840	COG3700	Belongs to the class B bacterial acid phosphatase family
ND05_RS04845	COG0432	Pfam Uncharacterised protein family UPF0047
ND05_RS04850	COG2315	Protein conserved in bacteria
ND05_RS04855	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ND05_RS04865	COG0629	single-stranded DNA binding
ND05_RS04880	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ND05_RS04885	COG2207	Transcriptional regulator
ND05_RS04890	COG0789	Transcriptional regulator
ND05_RS04910	COG2252	PERMEase
ND05_RS04915	COG0025	NhaP-type Na H and K H
ND05_RS04930	COG3162	membrane
ND05_RS04935	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ND05_RS04950	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
ND05_RS04955	COG0437	4 iron, 4 sulfur cluster binding
ND05_RS04960	COG3301	Polysulphide reductase, NrfD
ND05_RS04965	COG1138	Cytochrome C-type biogenesis protein
ND05_RS04970	COG3088	subunit of a heme lyase
ND05_RS04975	COG4235	cytochrome complex assembly
ND05_RS04985	COG1301	dicarboxylic acid transport
ND05_RS04990	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ND05_RS05005	COG1289	transmembrane transporter activity
ND05_RS05010	COG1566	PFAM secretion protein HlyD family protein
ND05_RS05020	COG2015	COG2015, Alkyl sulfatase and related hydrolases
ND05_RS05025	COG1940	carbohydrate kinase activity
ND05_RS05030	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ND05_RS05035	COG1172	Belongs to the binding-protein-dependent transport system permease family
ND05_RS05040	COG1129	ABC transporter
ND05_RS05045	COG1879	ABC-type sugar transport system periplasmic component
ND05_RS05050	COG1737	Transcriptional regulator
ND05_RS05060	COG0698	ribose 5-phosphate isomerase
ND05_RS05070	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ND05_RS05075	COG0456	acetyltransferase
ND05_RS05080	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
ND05_RS05085	COG3454	Phosphonate metabolism
ND05_RS05090	COG4778	phosphonate C-P lyase system protein PhnL
ND05_RS05095	COG4107	phosphonate C-P lyase system protein PhnK
ND05_RS05100	COG3627	carbon phosphorus lyase activity
ND05_RS05105	COG3626	phosphonate metabolism
ND05_RS05110	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
ND05_RS05115	COG3624	Phosphonate C-P lyase system protein PhnG
ND05_RS05120	COG2188	Transcriptional regulator
ND05_RS05125	COG3639	organic phosphonate transmembrane transporter activity
ND05_RS05130	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
ND05_RS05140	COG2764	glyoxalase bleomycin resistance protein dioxygenase
ND05_RS05145	COG2824	Alkylphosphonate utilization operon protein PhnA
ND05_RS05165	COG0477	Major facilitator Superfamily
ND05_RS05175	COG0642	Histidine kinase
ND05_RS05180	COG0745	RESPONSE REGULATOR receiver
ND05_RS05185	COG2194	sulfuric ester hydrolase activity
ND05_RS05190	COG0531	amino acid
ND05_RS05195	COG2207	Transcriptional regulator
ND05_RS05200	COG1982	Orn Lys Arg decarboxylase major
ND05_RS05205	COG2169	Transcriptional regulator
ND05_RS05210	COG1486	melibiose metabolic process
ND05_RS05215	COG2211	Major facilitator Superfamily
ND05_RS05225	COG3647	Membrane
ND05_RS05230	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ND05_RS05230	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ND05_RS05235	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ND05_RS05250	COG4565	transcriptional regulatory protein
ND05_RS05255	COG3290	protein histidine kinase activity
ND05_RS05260	COG3592	Divergent 4Fe-4S mono-cluster
ND05_RS05265	COG2388	GCN5-related N-acetyl-transferase
ND05_RS05285	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ND05_RS05290	COG3104	oligopeptide transport
ND05_RS05295	COG1982	Orn Lys Arg decarboxylase major
ND05_RS05300	COG0531	amino acid
ND05_RS05305	COG3710	Transcriptional regulator
ND05_RS05310	COG4372	Transposase
ND05_RS05315	COG3436	PFAM IS66 Orf2 family protein
ND05_RS05420	COG3436	PFAM IS66 Orf2 family protein
ND05_RS05440	COG0582	viral genome integration into host DNA
ND05_RS05450	COG1309	transcriptional regulator
ND05_RS05465	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ND05_RS05470	COG1027	Aspartate ammonia-lyase
ND05_RS05475	COG3030	protein affecting phage T7 exclusion by the F plasmid
ND05_RS05480	COG0531	amino acid
ND05_RS05505	COG1509	lysine 2,3-aminomutase activity
ND05_RS05515	COG5510	response to toxic substance
ND05_RS05520	COG5510	response to toxic substance
ND05_RS05525	COG2076	Multidrug Resistance protein
ND05_RS05530	COG3040	lipid binding
ND05_RS05535	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ND05_RS05550	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ND05_RS05555	COG1053	succinate dehydrogenase
ND05_RS05565	COG0531	amino acid
ND05_RS05580	COG3264	Mechanosensitive ion channel
ND05_RS05580	COG1511	domain protein
ND05_RS05620	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ND05_RS05625	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ND05_RS05625	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ND05_RS05630	COG0802	atpase or kinase
ND05_RS05635	COG0860	N-Acetylmuramoyl-L-alanine amidase
ND05_RS05655	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ND05_RS05660	COG0330	HflC and HflK could
ND05_RS05665	COG0330	HflC and HflK could
ND05_RS05670	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
ND05_RS05685	COG0557	exoribonuclease II activity
ND05_RS05690	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ND05_RS05700	COG3789	protein conserved in bacteria
ND05_RS05705	COG1842	Phage shock protein A
ND05_RS05715	COG3766	membrane
ND05_RS05720	COG5463	Belongs to the UPF0441 family
ND05_RS05725	COG0754	glutathionylspermidine amidase activity
ND05_RS05730	COG1960	acyl-CoA dehydrogenase activity
ND05_RS05740	COG3650	response to hydrogen peroxide
ND05_RS05745	COG1073	alpha beta
ND05_RS05760	COG3037	sugar-specific permease SgaT UlaA
ND05_RS05805	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ND05_RS05815	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ND05_RS05825	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ND05_RS05830	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ND05_RS05835	COG4670	ketone body catabolic process
ND05_RS05840	COG1024	Enoyl-CoA hydratase
ND05_RS05855	COG1309	transcriptional regulator
ND05_RS05860	COG3061	Opacity-associated protein A
ND05_RS05870	COG0545	Peptidyl-prolyl cis-trans isomerase
ND05_RS05875	COG1113	amino acid transport
ND05_RS05885	COG0697	spore germination
ND05_RS05890	COG0702	epimerase
ND05_RS05895	COG1733	regulation of RNA biosynthetic process
ND05_RS05900	COG0737	Belongs to the 5'-nucleotidase family
ND05_RS05905	COG1218	3'(2'),5'-bisphosphate nucleotidase
ND05_RS05910	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
ND05_RS05920	COG1253	flavin adenine dinucleotide binding
ND05_RS05935	COG0729	surface antigen
ND05_RS05940	COG2911	Protein conserved in bacteria
ND05_RS05945	COG2105	PFAM AIG2 family protein
ND05_RS05950	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ND05_RS05955	COG1879	ABC-type sugar transport system periplasmic component
ND05_RS05960	COG1129	ABC transporter
ND05_RS05965	COG1172	Belongs to the binding-protein-dependent transport system permease family
ND05_RS05980	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ND05_RS05990	COG0312	modulator of DNA gyrase
ND05_RS05995	COG3783	Cytochrome b(562)
ND05_RS06000	COG0602	queuosine metabolic process
ND05_RS06005	COG1328	CTP reductase activity
ND05_RS06010	COG0366	Alpha amylase catalytic
ND05_RS06015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ND05_RS06015	COG1263	PTS System
ND05_RS06020	COG1609	Transcriptional regulator
ND05_RS06030	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ND05_RS06035	COG0251	oxidation-reduction process
ND05_RS06060	COG0251	oxidation-reduction process
ND05_RS06065	COG1028	Short-chain dehydrogenase reductase Sdr
ND05_RS06070	COG1309	transcriptional regulator
ND05_RS06075	COG2731	YhcH YjgK YiaL family protein
ND05_RS06090	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
ND05_RS06095	COG0456	acetyltransferase
ND05_RS06105	COG0525	valine-tRNA ligase activity
ND05_RS06110	COG2927	DNA polymerase III (CHI subunit)
ND05_RS06120	COG0795	lipopolysaccharide-transporting ATPase activity
ND05_RS06125	COG0795	lipopolysaccharide-transporting ATPase activity
ND05_RS06130	COG0433	COG0433 Predicted ATPase
ND05_RS06135	COG1609	Transcriptional regulator
ND05_RS06140	COG2610	gluconate transmembrane transporter activity
ND05_RS06145	COG1028	Short-chain dehydrogenase reductase Sdr
ND05_RS06150	COG1063	alcohol dehydrogenase
ND05_RS06155	COG3265	gluconokinase activity
ND05_RS06160	COG1064	alcohol dehydrogenase
ND05_RS06175	COG0515	serine threonine protein kinase
ND05_RS06175	COG2815	serine threonine protein kinase
ND05_RS06230	COG1401	restriction endodeoxyribonuclease activity
ND05_RS06250	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
ND05_RS06255	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ND05_RS06265	COG0582	viral genome integration into host DNA
ND05_RS06270	COG4974	Belongs to the 'phage' integrase family
ND05_RS06275	COG3539	Fimbrial protein
ND05_RS06280	COG3539	Fimbrial protein
ND05_RS06285	COG3121	Chaperone
ND05_RS06290	COG3188	usher protein
ND05_RS06295	COG3539	Fimbrial protein
ND05_RS06300	COG3539	Fimbrial protein
ND05_RS06305	COG3539	Fimbrial protein
ND05_RS06325	COG0246	Mannitol dehydrogenase
ND05_RS06335	COG2186	Transcriptional regulator
ND05_RS06355	COG0583	DNA-binding transcription factor activity
ND05_RS06360	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ND05_RS06365	COG0700	Nucleoside recognition
ND05_RS06370	COG3366	ferrous iron transmembrane transporter activity
ND05_RS06385	COG0477	Major facilitator Superfamily
ND05_RS06400	COG1924	4 iron, 4 sulfur cluster binding
ND05_RS06405	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
ND05_RS06410	COG2733	membrane
ND05_RS06415	COG2814	Major facilitator Superfamily
ND05_RS06425	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ND05_RS06430	COG5457	Domain of unknown function (DUF1127)
ND05_RS06440	COG0523	cobalamin synthesis protein
ND05_RS06445	COG2879	small protein
ND05_RS06450	COG1966	Carbon starvation protein
ND05_RS06460	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ND05_RS06465	COG2368	4-hydroxyphenylacetate
ND05_RS06485	COG3971	2-oxopent-4-enoate hydratase activity
ND05_RS06495	COG3384	dioxygenase
ND05_RS06500	COG1012	belongs to the aldehyde dehydrogenase family
ND05_RS06505	COG0179	Fumarylacetoacetate (FAA) hydrolase
ND05_RS06510	COG1846	Transcriptional regulator
ND05_RS06515	COG0840	transmembrane signaling receptor activity
ND05_RS06520	COG2271	Major facilitator Superfamily
ND05_RS06525	COG1802	Transcriptional regulator
ND05_RS06530	COG1063	alcohol dehydrogenase
ND05_RS06545	COG1484	DNA-dependent DNA replication
ND05_RS06560	COG2966	Psort location CytoplasmicMembrane, score
ND05_RS06565	COG2197	response regulator
ND05_RS06570	COG2197	response regulator
ND05_RS06575	COG4114	ferric iron reductase
ND05_RS06605	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
ND05_RS06610	COG0456	acetyltransferase
ND05_RS06615	COG1011	Hydrolase
ND05_RS06650	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
ND05_RS06685	COG3646	Phage regulatory protein
ND05_RS06705	COG4725	Belongs to the MT-A70-like family
ND05_RS06715	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
ND05_RS06730	COG1403	HNH endonuclease
ND05_RS06800	COG3772	lysozyme
ND05_RS06855	COG5301	cellulose 1,4-beta-cellobiosidase activity
ND05_RS06900	COG2823	Periplasmic or secreted lipoprotein
ND05_RS06910	COG4667	esterase of the alpha-beta hydrolase superfamily
ND05_RS06915	COG0084	hydrolase, TatD family'
ND05_RS06920	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ND05_RS06925	COG1328	CTP reductase activity
ND05_RS06955	COG3726	membrane protein affecting hemolysin expression
ND05_RS06960	COG0560	Phosphoserine phosphatase
ND05_RS06965	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ND05_RS06970	COG1056	cytidyltransferase-related domain
ND05_RS06970	COG3172	ATPase kinase involved in NAD metabolism
ND05_RS06975	COG0488	(ABC) transporter
ND05_RS06985	COG0741	lytic transglycosylase activity
ND05_RS07005	COG3708	Transcriptional regulator
ND05_RS07005	COG2207	Transcriptional regulator
ND05_RS07015	COG0745	RESPONSE REGULATOR receiver
ND05_RS07020	COG2205	protein histidine kinase activity
ND05_RS07025	COG4452	Inner membrane protein CreD
ND05_RS07030	COG0745	RESPONSE REGULATOR receiver
ND05_RS07045	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
ND05_RS07055	COG0460	homoserine dehydrogenase
ND05_RS07055	COG0527	aspartate kinase activity
ND05_RS07065	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ND05_RS07080	COG1115	amino acid carrier protein
ND05_RS07085	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ND05_RS07090	COG0521	Mo-molybdopterin cofactor biosynthetic process
ND05_RS07095	COG1584	GPR1 FUN34 yaaH family protein
ND05_RS07100	COG4735	regulation of single-species biofilm formation
ND05_RS07130	COG3119	arylsulfatase activity
ND05_RS07145	COG0583	DNA-binding transcription factor activity
ND05_RS07180	COG0196	riboflavin kinase activity
ND05_RS07195	COG1047	Peptidyl-prolyl cis-trans
ND05_RS07220	COG0505	Belongs to the CarA family
ND05_RS07225	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ND05_RS07280	COG0644	oxidoreductase
ND05_RS07285	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
ND05_RS07290	COG2271	Major facilitator Superfamily
ND05_RS07305	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ND05_RS07330	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ND05_RS07335	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ND05_RS07340	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ND05_RS07345	COG0564	pseudouridine synthase activity
ND05_RS07355	COG0417	DNA replication proofreading
ND05_RS07360	COG0235	Class ii aldolase
ND05_RS07370	COG1069	ribulokinase activity
ND05_RS07380	COG4977	sequence-specific DNA binding
ND05_RS07385	COG0586	Pfam SNARE associated Golgi protein
ND05_RS07395	COG1178	ABC-type Fe3 transport system permease component
ND05_RS07400	COG4143	(ABC) transporter
ND05_RS07415	COG2814	Major facilitator Superfamily
ND05_RS07430	COG0473	3-isopropylmalate dehydrogenase activity
ND05_RS07445	COG0583	DNA-binding transcription factor activity
ND05_RS07455	COG0440	acetolactate synthase activity
ND05_RS07465	COG1609	Transcriptional regulator
ND05_RS07490	COG3116	cell division
ND05_RS07495	COG0768	penicillin binding
ND05_RS07500	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ND05_RS07505	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ND05_RS07520	COG0772	Belongs to the SEDS family
ND05_RS07535	COG1181	Belongs to the D-alanine--D-alanine ligase family
ND05_RS07540	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ND05_RS07545	COG0849	cell division
ND05_RS07550	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ND05_RS07570	COG0494	nUDIX hydrolase
ND05_RS07585	COG0237	dephospho-CoA kinase activity
ND05_RS07595	COG1459	type II secretion system
ND05_RS07600	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ND05_RS07605	COG4969	Belongs to the N-Me-Phe pilin family
ND05_RS07615	COG0157	Belongs to the NadC ModD family
ND05_RS07620	COG3023	N-Acetylmuramoyl-L-alanine amidase
ND05_RS07625	COG3725	Membrane protein required for beta-lactamase induction
ND05_RS07630	COG1113	amino acid transport
ND05_RS07635	COG2186	Transcriptional regulator
ND05_RS07645	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ND05_RS07650	COG0508	dehydrogenase complex catalyzes the overall conversion of
ND05_RS07655	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ND05_RS07660	COG3064	Membrane
ND05_RS07670	COG1049	propionate catabolic process, 2-methylcitrate cycle
ND05_RS07695	COG2132	Multicopper oxidase
ND05_RS07700	COG4993	Dehydrogenase
ND05_RS07705	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ND05_RS07710	COG0288	reversible hydration of carbon dioxide
ND05_RS07715	COG1131	(ABC) transporter
ND05_RS07720	COG0842	Transport permease protein
ND05_RS07725	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ND05_RS07730	COG0726	polysaccharide deacetylase
ND05_RS07745	COG5464	transposase or invertase
ND05_RS07780	COG3539	Fimbrial protein
ND05_RS07785	COG3539	Fimbrial protein
ND05_RS07790	COG3539	Fimbrial protein
ND05_RS07795	COG3188	usher protein
ND05_RS07800	COG3121	Chaperone
ND05_RS07805	COG3539	Fimbrial protein
ND05_RS07810	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ND05_RS07815	COG0617	tRNA 3'-terminal CCA addition
ND05_RS07825	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ND05_RS07835	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ND05_RS07840	COG1643	Atp-dependent helicase
ND05_RS07850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ND05_RS07860	COG1120	ATPase activity
ND05_RS07865	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ND05_RS07870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ND05_RS07890	COG2860	membrane
ND05_RS07895	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ND05_RS07915	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ND05_RS07920	COG3835	regulator
ND05_RS07940	COG0024	Methionine aminopeptidase
ND05_RS07975	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ND05_RS07980	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ND05_RS07985	COG0575	Belongs to the CDS family
ND05_RS07990	COG0750	zinc metalloprotease
ND05_RS08000	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
ND05_RS08005	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ND05_RS08030	COG0587	DNA-directed DNA polymerase activity
ND05_RS08040	COG1982	Orn Lys Arg decarboxylase major
ND05_RS08045	COG0346	lactoylglutathione lyase activity
ND05_RS08055	COG4568	rho-dependent transcription termination
ND05_RS08065	COG4681	YaeQ
ND05_RS08070	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ND05_RS08075	COG3015	lipoprotein NlpE involved in copper resistance
ND05_RS08090	COG1720	tRNA m6t6A37 methyltransferase activity
ND05_RS08100	COG1464	Belongs to the NlpA lipoprotein family
ND05_RS08105	COG2011	ABC-type metal ion transport system permease component
ND05_RS08110	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ND05_RS08115	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ND05_RS08150	COG0656	L-ascorbic acid biosynthetic process
ND05_RS08155	COG0583	DNA-binding transcription factor activity
ND05_RS08165	COG2226	methyltransferase
ND05_RS08170	COG0741	lytic transglycosylase activity
ND05_RS08170	COG1388	LysM domain
ND05_RS08180	COG2226	methyltransferase
ND05_RS08190	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ND05_RS08220	COG3157	Type VI secretion system effector, Hcp
ND05_RS08315	COG3209	COG3209 Rhs family protein
ND05_RS08335	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ND05_RS08345	COG1960	acyl-CoA dehydrogenase activity
ND05_RS08355	COG0121	glutamine amidotransferase
ND05_RS08360	COG3034	peptidoglycan biosynthetic process
ND05_RS08365	COG3041	Addiction module toxin RelE StbE family
ND05_RS08370	COG3077	Addiction module antitoxin, RelB DinJ family
ND05_RS08375	COG0791	NLP P60 protein
ND05_RS08405	COG0454	-acetyltransferase
ND05_RS08415	COG1690	Belongs to the RtcB family
ND05_RS08420	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ND05_RS08425	COG2195	Cleaves the N-terminal amino acid of tripeptides
ND05_RS08445	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ND05_RS08465	COG0583	DNA-binding transcription factor activity
ND05_RS08470	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ND05_RS08475	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ND05_RS08480	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ND05_RS08485	COG2080	2 iron, 2 sulfur cluster binding
ND05_RS08500	COG0727	PFAM Uncharacterised protein family (UPF0153)
ND05_RS08505	COG3121	Chaperone
ND05_RS08515	COG3188	usher protein
ND05_RS08570	COG1388	LysM domain
ND05_RS08575	COG3708	Transcriptional regulator
ND05_RS08575	COG2207	Transcriptional regulator
ND05_RS08580	COG0656	L-ascorbic acid biosynthetic process
ND05_RS08585	COG3059	membrane
ND05_RS08595	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ND05_RS08600	COG2207	Transcriptional regulator
ND05_RS08605	COG0247	lactate metabolic process
ND05_RS08610	COG1139	Iron-sulfur cluster binding protein
ND05_RS08615	COG1556	Lactate utilization protein
ND05_RS08655	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ND05_RS08665	COG2771	luxR family
ND05_RS08665	COG2200	EAL domain
ND05_RS08670	COG0583	DNA-binding transcription factor activity
ND05_RS08685	COG0666	response to abiotic stimulus
ND05_RS08710	COG1304	FMN binding
ND05_RS08715	COG0549	Belongs to the carbamate kinase family
ND05_RS08720	COG0402	S-adenosylhomocysteine deaminase activity
ND05_RS08730	COG1879	ABC-type sugar transport system periplasmic component
ND05_RS08735	COG1129	ABC transporter
ND05_RS08740	COG1172	Belongs to the binding-protein-dependent transport system permease family
ND05_RS08750	COG1064	alcohol dehydrogenase
ND05_RS08765	COG1280	lysine exporter protein (LysE YggA)
ND05_RS08775	COG3829	transcription factor binding
ND05_RS08780	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ND05_RS08785	COG0372	Belongs to the citrate synthase family
ND05_RS08790	COG2079	MmgE PrpD family protein
ND05_RS08795	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ND05_RS08800	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ND05_RS08805	COG0402	S-adenosylhomocysteine deaminase activity
ND05_RS08810	COG0583	DNA-binding transcription factor activity
ND05_RS08815	COG0288	reversible hydration of carbon dioxide
ND05_RS08825	COG2807	transmembrane transport
ND05_RS08830	COG0110	maltose O-acetyltransferase activity
ND05_RS08835	COG2223	nitrite transmembrane transporter activity
ND05_RS08855	COG1609	Transcriptional regulator
ND05_RS08860	COG1414	Transcriptional regulator
ND05_RS08895	COG2814	Major facilitator Superfamily
ND05_RS08900	COG3122	Protein conserved in bacteria
ND05_RS08930	COG1215	transferase activity, transferring glycosyl groups
ND05_RS08935	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ND05_RS08945	COG4521	taurine ABC transporter
ND05_RS08955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ND05_RS08960	COG2175	clavaminate synthase activity
ND05_RS08965	COG0113	porphobilinogen synthase activity
ND05_RS08975	COG3468	outer membrane autotransporter barrel domain protein
ND05_RS08980	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ND05_RS08985	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ND05_RS08995	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
ND05_RS09020	COG1181	Belongs to the D-alanine--D-alanine ligase family
ND05_RS09035	COG1785	Belongs to the alkaline phosphatase family
ND05_RS09045	COG3706	GGDEF domain
ND05_RS09050	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ND05_RS09075	COG4126	flavin adenine dinucleotide binding
ND05_RS09105	COG2814	Major facilitator Superfamily
ND05_RS09110	COG0419	ATPase involved in DNA repair
ND05_RS09115	COG0420	3'-5' exonuclease activity
ND05_RS09120	COG0745	RESPONSE REGULATOR receiver
ND05_RS09125	COG5002	protein histidine kinase activity
ND05_RS09130	COG1114	Component of the transport system for branched-chain amino acids
ND05_RS09135	COG1113	amino acid transport
ND05_RS09140	COG0366	Alpha amylase catalytic
ND05_RS09160	COG1862	Preprotein translocase
ND05_RS09165	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ND05_RS09170	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ND05_RS09175	COG1403	HNH endonuclease
ND05_RS09180	COG3248	Nucleoside-binding outer membrane protein
ND05_RS09185	COG4238	major outer membrane lipoprotein
ND05_RS09195	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ND05_RS09195	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ND05_RS09210	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ND05_RS09215	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ND05_RS09220	COG0667	Aldo Keto reductase
ND05_RS09230	COG0142	geranyltranstransferase activity
ND05_RS09245	COG0693	protein deglycase activity
ND05_RS09250	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ND05_RS09260	COG2814	Major facilitator Superfamily
ND05_RS09285	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ND05_RS09290	COG1845	cytochrome c oxidase, subunit III
ND05_RS09295	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ND05_RS09300	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ND05_RS09305	COG2223	nitrite transmembrane transporter activity
ND05_RS09310	COG3056	Lipoprotein
ND05_RS09315	COG0271	Belongs to the BolA IbaG family
ND05_RS09340	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ND05_RS09345	COG0776	regulation of translation
ND05_RS09350	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ND05_RS09355	COG1555	photosystem II stabilization
ND05_RS09360	COG0824	Thioesterase
ND05_RS09370	COG4533	DNA binding
ND05_RS09380	COG1522	sequence-specific DNA binding
ND05_RS09385	COG1132	(ABC) transporter
ND05_RS09390	COG1132	(ABC) transporter
ND05_RS09395	COG0347	Belongs to the P(II) protein family
ND05_RS09400	COG0004	ammonium transporteR
ND05_RS09405	COG1946	Acyl-CoA thioesterase
ND05_RS09410	COG3126	Type III secretion system lipoprotein chaperone (YscW)
ND05_RS09415	COG3695	enzyme binding
ND05_RS09425	COG5507	3-demethylubiquinone-9 3-methyltransferase
ND05_RS09430	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ND05_RS09440	COG0110	maltose O-acetyltransferase activity
ND05_RS09455	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ND05_RS09460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ND05_RS09465	COG1309	transcriptional regulator
ND05_RS09475	COG4372	Transposase
ND05_RS09480	COG3436	PFAM IS66 Orf2 family protein
ND05_RS09490	COG1196	nuclear chromosome segregation
ND05_RS09490	COG3264	Mechanosensitive ion channel
ND05_RS09500	COG3923	Primosomal replication protein n
ND05_RS09505	COG2832	Protein of unknown function (DUF454)
ND05_RS09520	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ND05_RS09560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ND05_RS09565	COG4651	solute:proton antiporter activity
ND05_RS09565	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ND05_RS09570	COG2223	nitrite transmembrane transporter activity
ND05_RS09580	COG0737	Belongs to the 5'-nucleotidase family
ND05_RS09585	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ND05_RS09595	COG3735	TraB family
ND05_RS09605	COG3093	addiction module antidote protein HigA
ND05_RS09610	COG2217	Heavy metal translocating P-type atpase
ND05_RS09620	COG0531	amino acid
ND05_RS09625	COG0789	Transcriptional regulator
ND05_RS09630	COG1585	Membrane protein implicated in regulation of membrane protease activity
ND05_RS09635	COG0330	HflC and HflK could
ND05_RS09640	COG4619	ABC transporter
ND05_RS09645	COG0390	transport system, permease component
ND05_RS09650	COG3118	belongs to the thioredoxin family
ND05_RS09655	COG0300	oxidoreductase activity
ND05_RS09660	COG2755	lipolytic protein G-D-S-L family
ND05_RS09665	COG4181	ATPase activity
ND05_RS09670	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ND05_RS09675	COG3209	COG3209 Rhs family protein
ND05_RS09695	COG0583	DNA-binding transcription factor activity
ND05_RS09705	COG1414	Transcriptional regulator
ND05_RS09710	COG3960	tartronate-semialdehyde synthase activity
ND05_RS09715	COG3622	Belongs to the hyi family
ND05_RS09720	COG2084	Dehydrogenase
ND05_RS09725	COG1953	Uracil, thiamine, allantoin
ND05_RS09735	COG2233	PERMEase
ND05_RS09740	COG1929	Belongs to the glycerate kinase type-1 family
ND05_RS09745	COG3257	ureidoglycine aminohydrolase activity
ND05_RS09750	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ND05_RS09755	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ND05_RS09760	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ND05_RS09765	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ND05_RS09775	COG0549	Belongs to the carbamate kinase family
ND05_RS09780	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ND05_RS09785	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ND05_RS09800	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ND05_RS09810	COG1988	membrane-bound metal-dependent
ND05_RS09815	COG2501	S4 domain
ND05_RS09825	COG3539	Fimbrial protein
ND05_RS09835	COG3188	usher protein
ND05_RS09840	COG3539	Fimbrial protein
ND05_RS09845	COG3539	Fimbrial protein
ND05_RS09850	COG2197	response regulator
ND05_RS09860	COG0582	viral genome integration into host DNA
ND05_RS09890	COG4220	transposase activity
ND05_RS09910	COG1030	water channel activity
ND05_RS09960	COG1196	nuclear chromosome segregation
ND05_RS10010	COG5301	cellulose 1,4-beta-cellobiosidase activity
ND05_RS10015	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ND05_RS10025	COG0500	methyltransferase
ND05_RS10040	COG4571	Outer membrane protease
ND05_RS10055	COG2207	Transcriptional regulator
ND05_RS10070	COG4783	chaperone-mediated protein folding
ND05_RS10075	COG1215	transferase activity, transferring glycosyl groups
ND05_RS10080	COG5433	transposase activity
ND05_RS10130	COG4104	PAAR repeat-containing protein
ND05_RS10130	COG3209	COG3209 Rhs family protein
ND05_RS10140	COG3501	Rhs element vgr protein
ND05_RS10145	COG5002	protein histidine kinase activity
ND05_RS10150	COG0745	RESPONSE REGULATOR receiver
ND05_RS10160	COG1538	Outer membrane efflux protein
ND05_RS10165	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ND05_RS10170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ND05_RS10175	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ND05_RS10180	COG1113	amino acid transport
ND05_RS10185	COG0668	transmembrane transport
ND05_RS10190	COG0778	Nitroreductase
ND05_RS10195	COG2315	Protein conserved in bacteria
ND05_RS10230	COG2977	Belongs to the P-Pant transferase superfamily
ND05_RS10235	COG4771	TonB-dependent receptor
ND05_RS10245	COG2382	esterase
ND05_RS10250	COG3251	PFAM MbtH domain protein
ND05_RS10255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ND05_RS10255	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
ND05_RS10265	COG1120	ATPase activity
ND05_RS10270	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ND05_RS10275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ND05_RS10285	COG4592	Periplasmic binding protein
ND05_RS10295	COG1169	isochorismate synthase
ND05_RS10300	COG1021	2,3-dihydroxybenzoate-AMP ligase
ND05_RS10310	COG1028	Short-chain dehydrogenase reductase Sdr
ND05_RS10315	COG2050	protein possibly involved in aromatic compounds catabolism
ND05_RS10320	COG1966	Carbon starvation protein
ND05_RS10325	COG2879	small protein
ND05_RS10330	COG0371	Dehydrogenase
ND05_RS10335	COG0436	Aminotransferase
ND05_RS10340	COG1475	DNA binding
ND05_RS10345	COG3969	phosphoadenosine phosphosulfate
ND05_RS10350	COG0583	DNA-binding transcription factor activity
ND05_RS10355	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ND05_RS10360	COG0450	alkyl hydroperoxide reductase
ND05_RS10365	COG3634	alkyl hydroperoxide reductase activity
ND05_RS10370	COG0589	response to stress
ND05_RS10375	COG1063	alcohol dehydrogenase
ND05_RS10385	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ND05_RS10395	COG3719	Belongs to the RNase T2 family
ND05_RS10400	COG0471	metal ion transport
ND05_RS10415	COG3051	citrate lyase alpha subunit
ND05_RS10420	COG2301	Belongs to the HpcH HpaI aldolase family
ND05_RS10430	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
ND05_RS10435	COG3290	protein histidine kinase activity
ND05_RS10440	COG4565	transcriptional regulatory protein
ND05_RS10445	COG3069	C4-dicarboxylate transmembrane transporter activity
ND05_RS10470	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ND05_RS10475	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ND05_RS10490	COG0583	DNA-binding transcription factor activity
ND05_RS10510	COG1686	Belongs to the peptidase S11 family
ND05_RS10515	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ND05_RS10520	COG0772	Belongs to the SEDS family
ND05_RS10525	COG0768	penicillin binding
ND05_RS10535	COG0799	negative regulation of ribosome biogenesis
ND05_RS10540	COG0406	alpha-ribazole phosphatase activity
ND05_RS10550	COG1466	dna polymerase III delta subunit
ND05_RS10565	COG2888	peptidyl-tyrosine sulfation
ND05_RS10570	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ND05_RS10580	COG2214	Heat shock protein DnaJ domain protein
ND05_RS10605	COG2214	Heat shock protein DnaJ domain protein
ND05_RS10610	COG0443	Heat shock 70 kDa protein
ND05_RS10620	COG1126	abc transporter atp-binding protein
ND05_RS10625	COG0765	amino acid transport
ND05_RS10630	COG0765	amino acid transport
ND05_RS10635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ND05_RS10650	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ND05_RS10655	COG4535	Mg2 and Co2 transporter CorC
ND05_RS10665	COG1702	phosphate starvation-inducible protein PhoH
ND05_RS10675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ND05_RS10720	COG0367	asparagine synthase
ND05_RS10730	COG0647	UMP catabolic process
ND05_RS10735	COG1940	carbohydrate kinase activity
ND05_RS10735	COG1846	Transcriptional regulator
ND05_RS10740	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ND05_RS10750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ND05_RS10750	COG2190	(PTS) system
ND05_RS10750	COG1263	PTS System
ND05_RS10770	COG0735	belongs to the Fur family
ND05_RS10780	COG0716	FMN binding
ND05_RS10790	COG0596	Alpha beta hydrolase
ND05_RS10795	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
ND05_RS10800	COG0033	Phosphoglucomutase
ND05_RS10805	COG0531	amino acid
ND05_RS10810	COG1982	Orn Lys Arg decarboxylase major
ND05_RS10820	COG0745	RESPONSE REGULATOR receiver
ND05_RS10825	COG2205	protein histidine kinase activity
ND05_RS10910	COG3272	Protein of unknown function (DUF1722)
ND05_RS10915	COG0415	Belongs to the DNA photolyase family
ND05_RS10925	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ND05_RS10930	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ND05_RS10935	COG1984	allophanate hydrolase subunit 2
ND05_RS10950	COG3180	Ammonia monooxygenase
ND05_RS10955	COG3539	Fimbrial protein
ND05_RS10960	COG3121	Chaperone
ND05_RS10965	COG3188	usher protein
ND05_RS10970	COG3539	Fimbrial protein
ND05_RS10975	COG0372	Belongs to the citrate synthase family
ND05_RS10990	COG2009	succinate dehydrogenase
ND05_RS10995	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ND05_RS11000	COG1053	succinate dehydrogenase
ND05_RS11005	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ND05_RS11010	COG0567	Dehydrogenase, E1 component
ND05_RS11015	COG0508	dehydrogenase complex catalyzes the overall conversion of
ND05_RS11025	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ND05_RS11030	COG2188	Transcriptional regulator
ND05_RS11035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ND05_RS11035	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ND05_RS11035	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ND05_RS11040	COG0383	alpha-mannosidase activity
ND05_RS11050	COG1271	oxidase subunit
ND05_RS11055	COG1294	oxidase, subunit
ND05_RS11060	COG4890	Cyd operon protein YbgT
ND05_RS11065	COG3790	cyd operon protein YbgE
ND05_RS11070	COG0824	Thioesterase
ND05_RS11075	COG0811	peptide transport
ND05_RS11080	COG0848	biopolymer transport protein
ND05_RS11085	COG3064	Membrane
ND05_RS11095	COG2885	chlorophyll binding
ND05_RS11100	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
ND05_RS11145	COG3201	nicotinamide mononucleotide transporter
ND05_RS11150	COG1230	cation diffusion facilitator family transporter
ND05_RS11165	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ND05_RS11175	COG2017	converts alpha-aldose to the beta-anomer
ND05_RS11185	COG1085	galactose-1-phosphate uridylyltransferase
ND05_RS11190	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ND05_RS11195	COG1119	ATPase activity
ND05_RS11200	COG3585	molybdate ion transport
ND05_RS11200	COG2005	Transcriptional regulator
ND05_RS11215	COG0725	ABC transporter, periplasmic molybdate-binding protein
ND05_RS11220	COG4149	molybdate abc transporter
ND05_RS11230	COG0561	phosphatase activity
ND05_RS11240	COG0583	DNA-binding transcription factor activity
ND05_RS11245	COG2828	Protein conserved in bacteria
ND05_RS11250	COG0471	metal ion transport
ND05_RS11255	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ND05_RS11260	COG4677	pectinesterase activity
ND05_RS11270	COG1881	PFAM PEBP family protein
ND05_RS11275	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ND05_RS11290	COG2226	methyltransferase
ND05_RS11295	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ND05_RS11305	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ND05_RS11315	COG0521	Mo-molybdopterin cofactor biosynthetic process
ND05_RS11325	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ND05_RS11330	COG0314	molybdopterin synthase activity
ND05_RS11335	COG0670	Belongs to the BI1 family
ND05_RS11345	COG0670	Belongs to the BI1 family
ND05_RS11350	COG0392	lysyltransferase activity
ND05_RS11355	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ND05_RS11360	COG3568	Endonuclease Exonuclease Phosphatase
ND05_RS11370	COG0842	Transport permease protein
ND05_RS11375	COG0842	Transport permease protein
ND05_RS11380	COG1131	(ABC) transporter
ND05_RS11390	COG1309	transcriptional regulator
ND05_RS11400	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
ND05_RS11410	COG1199	ATP-dependent helicase activity
ND05_RS11415	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ND05_RS11420	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ND05_RS11430	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ND05_RS11440	COG4774	siderophore transport
ND05_RS11455	COG0668	transmembrane transport
ND05_RS11460	COG1126	abc transporter atp-binding protein
ND05_RS11465	COG0765	amino acid transport
ND05_RS11470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ND05_RS11495	COG5006	permease, DMT superfamily
ND05_RS11500	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ND05_RS11505	COG2194	sulfuric ester hydrolase activity
ND05_RS11515	COG1321	iron dependent repressor
ND05_RS11520	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ND05_RS11525	COG1376	ErfK ybiS ycfS ynhG family protein
ND05_RS11530	COG0488	(ABC) transporter
ND05_RS11540	COG0561	phosphatase activity
ND05_RS11545	COG1882	Formate acetyltransferase
ND05_RS11550	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ND05_RS11555	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ND05_RS11560	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ND05_RS11565	COG0303	'Molybdopterin
ND05_RS11570	COG1446	asparaginase
ND05_RS11595	COG2200	EAL domain
ND05_RS11600	COG2199	diguanylate cyclase activity
ND05_RS11615	COG2133	pyrroloquinoline quinone binding
ND05_RS11625	COG1686	Belongs to the peptidase S11 family
ND05_RS11630	COG1349	DNA-binding transcription factor activity
ND05_RS11635	COG0671	phosphoesterase, PA-phosphatase related
ND05_RS11640	COG2814	Major facilitator Superfamily
ND05_RS11650	COG0561	phosphatase activity
ND05_RS11655	COG0738	Major facilitator superfamily
ND05_RS11660	COG3226	Transcriptional regulator
ND05_RS11675	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ND05_RS11685	COG0778	Nitroreductase
ND05_RS11705	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ND05_RS11710	COG3842	ATPase activity
ND05_RS11715	COG1176	ABC-type spermidine putrescine transport system, permease component I
ND05_RS11720	COG1177	transmembrane transport
ND05_RS11735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ND05_RS11740	COG4160	amino acid transport
ND05_RS11745	COG4215	(ABC) transporter
ND05_RS11750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ND05_RS11755	COG1126	abc transporter atp-binding protein
ND05_RS11770	COG3023	N-Acetylmuramoyl-L-alanine amidase
ND05_RS11775	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ND05_RS11780	COG0702	epimerase
ND05_RS11785	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
ND05_RS11790	COG0028	Belongs to the TPP enzyme family
ND05_RS11795	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ND05_RS11805	COG2431	L-lysine efflux transmembrane transporter activity
ND05_RS11820	COG3593	DNA synthesis involved in DNA repair
ND05_RS11825	COG2990	Protein conserved in bacteria
ND05_RS11830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ND05_RS11840	COG1278	Cold shock
ND05_RS11850	COG0542	response to heat
ND05_RS11855	COG4372	Transposase
ND05_RS11860	COG3436	PFAM IS66 Orf2 family protein
ND05_RS11885	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ND05_RS11890	COG4988	ABC transporter
ND05_RS11895	COG0492	ferredoxin-NADP+ reductase activity
ND05_RS11905	COG1522	sequence-specific DNA binding
ND05_RS11910	COG1674	ftsk spoiiie
ND05_RS11910	COG1178	ABC-type Fe3 transport system permease component
ND05_RS11920	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ND05_RS11930	COG0243	molybdopterin cofactor binding
ND05_RS11935	COG0437	4 iron, 4 sulfur cluster binding
ND05_RS11940	COG3302	dmso reductase anchor subunit
ND05_RS11945	COG1335	isochorismatase
ND05_RS11955	COG0531	amino acid
ND05_RS11960	COG0583	DNA-binding transcription factor activity
ND05_RS11965	COG2249	NAD(P)H dehydrogenase (quinone) activity
ND05_RS11970	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ND05_RS11975	COG1882	Formate acetyltransferase
ND05_RS11980	COG2116	formate transmembrane transporter activity
ND05_RS11985	COG1944	ATP diphosphatase activity
ND05_RS11990	COG2323	membrane
ND05_RS12005	COG0501	Belongs to the peptidase M48B family
ND05_RS12015	COG0539	negative regulation of cytoplasmic translation
ND05_RS12025	COG2333	competence protein COMEC
ND05_RS12025	COG0658	competence protein
ND05_RS12030	COG1132	(ABC) transporter
ND05_RS12040	COG3214	Protein conserved in bacteria
ND05_RS12055	COG3173	Aminoglycoside phosphotransferase
ND05_RS12060	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ND05_RS12065	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ND05_RS12075	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
ND05_RS12085	COG2989	Protein conserved in bacteria
ND05_RS12095	COG3108	Peptidase M15
ND05_RS12100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ND05_RS12105	COG1448	Aminotransferase
ND05_RS12125	COG0308	aminopeptidase N
ND05_RS12135	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ND05_RS12145	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ND05_RS12150	COG0431	NADPH-dependent FMN reductase
ND05_RS12155	COG3539	Fimbrial protein
ND05_RS12170	COG3539	Fimbrial protein
ND05_RS12175	COG3539	Fimbrial protein
ND05_RS12180	COG3539	Fimbrial protein
ND05_RS12185	COG3121	Chaperone
ND05_RS12200	COG0633	Ferredoxin
ND05_RS12200	COG3217	Mosc domain protein beta barrel domain protein
ND05_RS12210	COG0488	(ABC) transporter
ND05_RS12215	COG2995	paraquat-inducible protein a
ND05_RS12220	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ND05_RS12220	COG3008	intermembrane lipid transfer
ND05_RS12225	COG3009	Protein conserved in bacteria
ND05_RS12230	COG3130	regulation of translation
ND05_RS12240	COG1067	ATP-dependent peptidase activity
ND05_RS12265	COG3070	regulator of competence-specific genes
ND05_RS12270	COG1289	transmembrane transporter activity
ND05_RS12275	COG3304	Inner membrane component domain
ND05_RS12280	COG0210	DNA helicase
ND05_RS12295	COG1832	CoA-binding protein
ND05_RS12310	COG1254	Belongs to the acylphosphatase family
ND05_RS12315	COG2920	part of a sulfur-relay system
ND05_RS12320	COG0670	Belongs to the BI1 family
ND05_RS12335	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ND05_RS12370	COG4197	protein conserved in bacteria, prophage-related
ND05_RS12445	COG1403	HNH endonuclease
ND05_RS12450	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
ND05_RS12495	COG3772	lysozyme
ND05_RS12530	COG0740	serine-type endopeptidase activity
ND05_RS12605	COG5301	cellulose 1,4-beta-cellobiosidase activity
ND05_RS12665	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ND05_RS12740	COG1484	DNA-dependent DNA replication
ND05_RS12745	COG1846	Transcriptional regulator
ND05_RS12770	COG1403	HNH endonuclease
ND05_RS12775	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
ND05_RS12795	COG2207	Transcriptional regulator
ND05_RS12855	COG3772	lysozyme
ND05_RS12885	COG4220	transposase activity
ND05_RS12990	COG5301	cellulose 1,4-beta-cellobiosidase activity
ND05_RS13030	COG1879	ABC-type sugar transport system periplasmic component
ND05_RS13035	COG0745	RESPONSE REGULATOR receiver
ND05_RS13040	COG3005	denitrification pathway
ND05_RS13045	COG0243	molybdopterin cofactor binding
ND05_RS13090	COG3729	General stress protein
ND05_RS13095	COG2233	PERMEase
ND05_RS13130	COG1309	transcriptional regulator
ND05_RS13135	COG0506	proline dehydrogenase activity
ND05_RS13135	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ND05_RS13135	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ND05_RS13150	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ND05_RS13170	COG2822	iron ion transport
ND05_RS13180	COG1702	phosphate starvation-inducible protein PhoH
ND05_RS13210	COG3381	protein complex oligomerization
ND05_RS13220	COG1462	curli production assembly transport component CsgG
ND05_RS13235	COG2197	response regulator
ND05_RS13270	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ND05_RS13275	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ND05_RS13300	COG2943	transferase activity, transferring hexosyl groups
ND05_RS13305	COG5645	(Lipo)protein
ND05_RS13320	COG1560	Kdo2-lipid A biosynthetic process
ND05_RS13330	COG2353	YceI-like domain
ND05_RS13335	COG3038	cytochrome b561
ND05_RS13375	COG2999	glutathione oxidoreductase activity
ND05_RS13385	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ND05_RS13395	COG0673	inositol 2-dehydrogenase activity
ND05_RS13400	COG0728	peptidoglycan biosynthetic process
ND05_RS13405	COG3418	PFAM FlgN family protein
ND05_RS13410	COG2747	anti-sigma28 factor FlgM
ND05_RS13420	COG1815	bacterial-type flagellum-dependent cell motility
ND05_RS13425	COG1558	bacterial-type flagellum-dependent cell motility
ND05_RS13430	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ND05_RS13435	COG1749	Flagellar hook protein flgE
ND05_RS13440	COG4787	bacterial-type flagellum-dependent cell motility
ND05_RS13445	COG4786	Flagellar basal body rod
ND05_RS13460	COG1705	Flagellar rod assembly protein muramidase FlgJ
ND05_RS13460	COG3951	Flagellar rod assembly protein muramidase FlgJ
ND05_RS13465	COG1256	bacterial-type flagellum assembly
ND05_RS13470	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ND05_RS13475	COG1530	ribonuclease E activity
ND05_RS13485	COG0564	pseudouridine synthase activity
ND05_RS13490	COG0424	maF-like protein
ND05_RS13495	COG1399	metal-binding, possibly nucleic acid-binding protein
ND05_RS13515	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ND05_RS13520	COG1028	Short-chain dehydrogenase reductase Sdr
ND05_RS13530	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ND05_RS13535	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ND05_RS13540	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ND05_RS13550	COG0470	DNA polymerase III
ND05_RS13555	COG0084	hydrolase, TatD family'
ND05_RS13560	COG1263	PTS System
ND05_RS13560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ND05_RS13565	COG4773	Receptor
ND05_RS13570	COG0537	adenosine 5'-monophosphoramidase activity
ND05_RS13575	COG5633	Lipoprotein
ND05_RS13580	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
ND05_RS13600	COG1252	NADH dehydrogenase
ND05_RS13610	COG3134	Outer membrane lipoprotein
ND05_RS13615	COG1309	transcriptional regulator
ND05_RS13625	COG1376	ErfK ybiS ycfS ynhG family protein
ND05_RS13625	COG1388	LysM domain
ND05_RS13630	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ND05_RS13635	COG4763	Acyl-transferase
ND05_RS13640	COG4591	ABC-type transport system involved in lipoprotein release permease component
ND05_RS13650	COG4591	ABC-type transport system involved in lipoprotein release permease component
ND05_RS13660	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ND05_RS13665	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ND05_RS13670	COG1177	transmembrane transport
ND05_RS13685	COG0582	viral genome integration into host DNA
ND05_RS13695	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ND05_RS13745	COG1846	Transcriptional regulator
ND05_RS13765	COG4372	Transposase
ND05_RS13770	COG3436	PFAM IS66 Orf2 family protein
ND05_RS13805	COG3111	PFAM Bacterial OB fold (BOF) protein
ND05_RS13815	COG1403	HNH endonuclease
ND05_RS13820	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
ND05_RS13825	COG0484	heat shock protein binding
ND05_RS13900	COG3772	lysozyme
ND05_RS14015	COG5301	cellulose 1,4-beta-cellobiosidase activity
ND05_RS14045	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
ND05_RS14050	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
ND05_RS14055	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ND05_RS14060	COG1999	signal sequence binding
ND05_RS14065	COG1773	rubredoxin
ND05_RS14070	COG1271	oxidase subunit
ND05_RS14075	COG1294	oxidase, subunit
ND05_RS14090	COG0489	protein tyrosine kinase activity
ND05_RS14090	COG3206	protein involved in exopolysaccharide biosynthesis
ND05_RS14095	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ND05_RS14100	COG1596	polysaccharide export
ND05_RS14105	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ND05_RS14125	COG1278	Cold shock
ND05_RS14130	COG1278	Cold shock
ND05_RS14150	COG0348	domain, Protein
ND05_RS14155	COG2205	protein histidine kinase activity
ND05_RS14155	COG0784	Response regulator, receiver
ND05_RS14155	COG2198	Histidine kinase
ND05_RS14160	COG0582	viral genome integration into host DNA
ND05_RS14325	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ND05_RS14375	COG3436	PFAM IS66 Orf2 family protein
ND05_RS14380	COG4372	Transposase
ND05_RS14395	COG3772	lysozyme
ND05_RS14420	COG4220	transposase activity
ND05_RS14590	COG3842	ATPase activity
ND05_RS14605	COG2850	peptidyl-arginine hydroxylation
ND05_RS14610	COG2205	protein histidine kinase activity
ND05_RS14620	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ND05_RS14640	COG1187	pseudouridine synthase activity
ND05_RS14645	COG0538	isocitrate dehydrogenase activity
ND05_RS14655	COG5562	phage envelope protein
ND05_RS14660	COG0789	Transcriptional regulator
ND05_RS14665	COG2200	EAL domain
ND05_RS14690	COG2200	EAL domain
ND05_RS14750	COG2894	cell division
ND05_RS14780	COG0179	Fumarylacetoacetate (FAA) hydrolase
ND05_RS14795	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ND05_RS14800	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ND05_RS14820	COG2719	SpoVR family
ND05_RS14830	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ND05_RS14840	COG1619	proteins homologs of microcin C7 resistance protein MccF
ND05_RS14855	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
ND05_RS14880	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ND05_RS14880	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ND05_RS14880	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
ND05_RS14885	COG1461	Dihydroxyacetone kinase
ND05_RS14890	COG2376	Dihydroxyacetone kinase
ND05_RS14895	COG3284	Transcriptional regulator
ND05_RS14900	COG3468	outer membrane autotransporter barrel domain protein
ND05_RS14915	COG0012	GTP binding
ND05_RS14930	COG0659	secondary active sulfate transmembrane transporter activity
ND05_RS14940	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ND05_RS14970	COG2890	protein-(glutamine-N5) methyltransferase activity
ND05_RS14975	COG3094	Invasion gene expression up-regulator, SirB
ND05_RS14980	COG2912	Transglutaminase-like superfamily
ND05_RS15005	COG0387	Pfam Sodium calcium exchanger
ND05_RS15010	COG4572	Cation transport regulator
ND05_RS15015	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
ND05_RS15020	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ND05_RS15025	COG4932	domain protein
ND05_RS15030	COG2197	response regulator
ND05_RS15035	COG3850	Histidine kinase
ND05_RS15045	COG2223	nitrite transmembrane transporter activity
ND05_RS15050	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ND05_RS15055	COG1140	nitrate reductase beta subunit
ND05_RS15060	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
ND05_RS15065	COG2181	nitrate reductase activity
ND05_RS15085	COG0788	formyltetrahydrofolate deformylase activity
ND05_RS15095	COG1752	Esterase of the alpha-beta hydrolase superfamily
ND05_RS15100	COG0745	RESPONSE REGULATOR receiver
ND05_RS15105	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ND05_RS15115	COG1435	thymidine kinase activity
ND05_RS15120	COG1012	belongs to the aldehyde dehydrogenase family
ND05_RS15120	COG1454	alcohol dehydrogenase
ND05_RS15125	COG2095	MarC family integral membrane protein
ND05_RS15135	COG4166	transmembrane transport
ND05_RS15140	COG0601	transmembrane transport
ND05_RS15145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ND05_RS15150	COG0444	Belongs to the ABC transporter superfamily
ND05_RS15155	COG4608	Belongs to the ABC transporter superfamily
ND05_RS15175	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ND05_RS15180	COG2350	Protein conserved in bacteria
ND05_RS15185	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
ND05_RS15190	COG1607	acyl-coa hydrolase
ND05_RS15210	COG3047	cAMP biosynthetic process
ND05_RS15225	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ND05_RS15270	COG1396	sequence-specific DNA binding
ND05_RS15290	COG1846	Transcriptional regulator
ND05_RS15325	COG1403	HNH endonuclease
ND05_RS15440	COG3685	Protein conserved in bacteria
ND05_RS15445	COG3685	Protein conserved in bacteria
ND05_RS15450	COG3729	General stress protein
ND05_RS15465	COG0134	indole-3-glycerol-phosphate synthase activity
ND05_RS15465	COG0135	phosphoribosylanthranilate isomerase activity
ND05_RS15470	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ND05_RS15470	COG0512	Glutamine amidotransferase of anthranilate synthase
ND05_RS15475	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ND05_RS15485	COG0613	PHP domain protein
ND05_RS15490	COG0009	L-threonylcarbamoyladenylate synthase
ND05_RS15495	COG1187	pseudouridine synthase activity
ND05_RS15500	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
ND05_RS15505	COG1028	Short-chain dehydrogenase reductase Sdr
ND05_RS15510	COG0616	signal peptide processing
ND05_RS15525	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ND05_RS15535	COG0583	DNA-binding transcription factor activity
ND05_RS15555	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ND05_RS15565	COG0671	phosphoesterase, PA-phosphatase related
ND05_RS15570	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
ND05_RS15575	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ND05_RS15585	COG0023	Translation Initiation Factor
ND05_RS15595	COG1349	DNA-binding transcription factor activity
ND05_RS15605	COG5001	Diguanylate cyclase
ND05_RS15620	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ND05_RS15620	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ND05_RS15625	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ND05_RS15630	COG2852	Protein conserved in bacteria
ND05_RS15635	COG4172	Belongs to the ABC transporter superfamily
ND05_RS15640	COG4172	Belongs to the ABC transporter superfamily
ND05_RS15645	COG4171	peptide transport system, permease
ND05_RS15650	COG4168	peptide transport system, permease
ND05_RS15670	COG0531	amino acid
ND05_RS15675	COG0174	glutamine synthetase
ND05_RS15680	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ND05_RS15685	COG1917	Cupin 2, conserved barrel domain protein
ND05_RS15685	COG1396	sequence-specific DNA binding
ND05_RS15695	COG1012	belongs to the aldehyde dehydrogenase family
ND05_RS15700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ND05_RS15705	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ND05_RS15710	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ND05_RS15715	COG1842	Phage shock protein A
ND05_RS15725	COG1983	PspC domain protein
ND05_RS15735	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ND05_RS15740	COG0366	Alpha amylase catalytic
ND05_RS15750	COG1175	transmembrane transport
ND05_RS15755	COG0395	ABC-type sugar transport system, permease component
ND05_RS15760	COG1063	alcohol dehydrogenase
ND05_RS15765	COG1082	Xylose isomerase domain protein TIM barrel
ND05_RS15770	COG0673	inositol 2-dehydrogenase activity
ND05_RS15775	COG1554	hydrolase, family 65, central catalytic
ND05_RS15780	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ND05_RS15785	COG3842	ATPase activity
ND05_RS15795	COG1609	Transcriptional regulator
ND05_RS15800	COG3106	COG3106 Predicted ATPase
ND05_RS15810	COG3283	Transcriptional regulator of aromatic amino acids metabolism
ND05_RS15815	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ND05_RS15820	COG4948	Mandelate Racemase Muconate Lactonizing
ND05_RS15825	COG2866	Carboxypeptidase
ND05_RS15830	COG0702	epimerase
ND05_RS15835	COG1073	alpha beta
ND05_RS15840	COG1073	alpha beta
ND05_RS15845	COG0583	DNA-binding transcription factor activity
ND05_RS15850	COG4166	transmembrane transport
ND05_RS15855	COG0668	transmembrane transport
ND05_RS15860	COG3182	Iron-regulated membrane protein
ND05_RS15865	COG0589	response to stress
ND05_RS15870	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ND05_RS15875	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ND05_RS15880	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ND05_RS15890	COG1473	amidohydrolase
ND05_RS15895	COG1473	amidohydrolase
ND05_RS15900	COG0583	DNA-binding transcription factor activity
ND05_RS15910	COG2840	Smr protein MutS2
ND05_RS15915	COG3706	GGDEF domain
ND05_RS15930	COG0513	Belongs to the DEAD box helicase family
ND05_RS15940	COG0582	viral genome integration into host DNA
ND05_RS15960	COG3723	Recombinational DNA repair protein, rece pathway
ND05_RS15965	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ND05_RS16005	COG3756	Protein conserved in bacteria
ND05_RS16010	COG1484	DNA-dependent DNA replication
ND05_RS16015	COG1846	Transcriptional regulator
ND05_RS16115	COG3772	lysozyme
ND05_RS16155	COG0740	serine-type endopeptidase activity
ND05_RS16230	COG5301	cellulose 1,4-beta-cellobiosidase activity
ND05_RS16255	COG0589	response to stress
ND05_RS16260	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ND05_RS16265	COG1013	pyruvate-flavodoxin oxidoreductase activity
ND05_RS16265	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ND05_RS16265	COG0674	pyruvate-flavodoxin oxidoreductase activity
ND05_RS16265	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ND05_RS16270	COG3042	response to heat
ND05_RS16275	COG3187	Heat shock protein
ND05_RS16280	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ND05_RS16285	COG2911	Protein conserved in bacteria
ND05_RS16295	COG3784	Protein of unknown function (DUF1318)
ND05_RS16300	COG2207	Transcriptional regulator
ND05_RS16305	COG1012	belongs to the aldehyde dehydrogenase family
ND05_RS16310	COG3733	amine oxidase
ND05_RS16315	COG1012	belongs to the aldehyde dehydrogenase family
ND05_RS16315	COG2030	dehydratase
ND05_RS16320	COG3396	Phenylacetate-CoA oxygenase
ND05_RS16325	COG3460	Phenylacetate-CoA oxygenase
ND05_RS16330	COG3396	Phenylacetate-CoA oxygenase
ND05_RS16335	COG2151	metal-sulfur cluster biosynthetic enzyme
ND05_RS16340	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ND05_RS16345	COG1024	Enoyl-CoA hydratase
ND05_RS16350	COG1024	Enoyl-CoA hydratase
ND05_RS16355	COG1250	3-hydroxyacyl-CoA dehydrogenase
ND05_RS16360	COG2050	protein possibly involved in aromatic compounds catabolism
ND05_RS16365	COG0183	Belongs to the thiolase family
ND05_RS16370	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
ND05_RS16375	COG3327	negative regulation of DNA-templated transcription, initiation
ND05_RS16380	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ND05_RS16400	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ND05_RS16405	COG4589	Belongs to the CDS family
ND05_RS16415	COG2453	phosphatase
ND05_RS16415	COG0671	phosphoesterase, PA-phosphatase related
ND05_RS16425	COG1643	Atp-dependent helicase
ND05_RS16430	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ND05_RS16435	COG1012	belongs to the aldehyde dehydrogenase family
ND05_RS16440	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ND05_RS16445	COG3038	cytochrome b561
ND05_RS16460	COG0840	transmembrane signaling receptor activity
ND05_RS16465	COG0583	DNA-binding transcription factor activity
ND05_RS16470	COG5383	Protein conserved in bacteria
ND05_RS16490	COG2841	Protein conserved in bacteria
ND05_RS16495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ND05_RS16500	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ND05_RS16505	COG1275	C4-dicarboxylate transporter malic acid transport protein
ND05_RS16510	COG0500	methyltransferase
ND05_RS16530	COG0675	Transposase, IS605 OrfB family
ND05_RS16535	COG3135	benzoate transporter
ND05_RS16540	COG1396	sequence-specific DNA binding
ND05_RS16545	COG0826	peptidase U32
ND05_RS16555	COG1724	mRNA binding
ND05_RS16560	COG1598	PFAM Uncharacterised protein family UPF0150
ND05_RS16565	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ND05_RS16570	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ND05_RS16575	COG3842	ATPase activity
ND05_RS16580	COG1176	ABC-type spermidine putrescine transport system, permease component I
ND05_RS16585	COG1177	transmembrane transport
ND05_RS16620	COG3238	Protein conserved in bacteria
ND05_RS16625	COG1247	-acetyltransferase
ND05_RS16635	COG2130	NADP-dependent
ND05_RS16640	COG1802	Transcriptional regulator
ND05_RS16645	COG4772	TonB-dependent receptor
ND05_RS16655	COG3391	amine dehydrogenase activity
ND05_RS16665	COG0625	glutathione transferase activity
ND05_RS16690	COG5433	transposase activity
ND05_RS16695	COG5433	transposase activity
ND05_RS16705	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ND05_RS16710	COG2162	N-hydroxyarylamine O-acetyltransferase activity
ND05_RS16715	COG0384	phenazine biosynthesis protein PhzF
ND05_RS16720	COG2181	nitrate reductase activity
ND05_RS16725	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
ND05_RS16730	COG1140	nitrate reductase beta subunit
ND05_RS16735	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ND05_RS16740	COG2223	nitrite transmembrane transporter activity
ND05_RS16750	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ND05_RS16755	COG0697	spore germination
ND05_RS16760	COG3383	formate dehydrogenase (NAD+) activity
ND05_RS16760	COG0243	molybdopterin cofactor binding
ND05_RS16765	COG0243	molybdopterin cofactor binding
ND05_RS16765	COG3383	formate dehydrogenase (NAD+) activity
ND05_RS16770	COG0437	4 iron, 4 sulfur cluster binding
ND05_RS16775	COG2864	formate dehydrogenase
ND05_RS16780	COG3093	addiction module antidote protein HigA
ND05_RS16785	COG1064	alcohol dehydrogenase
ND05_RS16810	COG1764	response to oxidative stress
ND05_RS16815	COG4608	Belongs to the ABC transporter superfamily
ND05_RS16820	COG0444	Belongs to the ABC transporter superfamily
ND05_RS16825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ND05_RS16830	COG0601	transmembrane transport
ND05_RS16835	COG0747	negative chemotaxis
ND05_RS16840	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
ND05_RS16845	COG2202	Pas domain
ND05_RS16845	COG2200	EAL domain
ND05_RS16845	COG2199	diguanylate cyclase activity
ND05_RS16855	COG1649	PFAM Uncharacterised BCR, COG1649
ND05_RS16860	COG0531	amino acid
ND05_RS16865	COG0076	glutamate decarboxylase activity
ND05_RS16870	COG0612	Peptidase, M16
ND05_RS16875	COG4771	TonB-dependent receptor
ND05_RS16880	COG4178	(ABC) transporter
ND05_RS16885	COG0641	radical SAM
ND05_RS16895	COG2207	Transcriptional regulator
ND05_RS16905	COG0243	molybdopterin cofactor binding
ND05_RS16910	COG3539	Fimbrial protein
ND05_RS16915	COG3539	Fimbrial protein
ND05_RS16920	COG3539	Fimbrial protein
ND05_RS16925	COG3188	usher protein
ND05_RS16930	COG3121	Chaperone
ND05_RS16935	COG3539	Fimbrial protein
ND05_RS16950	COG3550	peptidyl-serine autophosphorylation
ND05_RS16955	COG1396	sequence-specific DNA binding
ND05_RS16965	COG2911	Protein conserved in bacteria
ND05_RS16965	COG3210	domain, Protein
ND05_RS17015	COG3781	membrane
ND05_RS17035	COG2199	diguanylate cyclase activity
ND05_RS17050	COG2066	Belongs to the glutaminase family
ND05_RS17055	COG1012	belongs to the aldehyde dehydrogenase family
ND05_RS17060	COG0583	DNA-binding transcription factor activity
ND05_RS17080	COG1846	Transcriptional regulator
ND05_RS17085	COG4977	sequence-specific DNA binding
ND05_RS17115	COG1447	Phosphotransferase system cellobiose-specific component IIA
ND05_RS17120	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ND05_RS17130	COG2188	Transcriptional regulator
ND05_RS17135	COG0697	spore germination
ND05_RS17140	COG2814	Major facilitator Superfamily
ND05_RS17150	COG3706	GGDEF domain
ND05_RS17165	COG3111	PFAM Bacterial OB fold (BOF) protein
ND05_RS17170	COG1546	Belongs to the CinA family
ND05_RS17175	COG0339	signal peptide processing
ND05_RS17185	COG4221	oxidoreductase activity
ND05_RS17190	COG1802	Transcriptional regulator
ND05_RS17205	COG0477	Major facilitator Superfamily
ND05_RS17235	COG5301	cellulose 1,4-beta-cellobiosidase activity
ND05_RS17320	COG1030	water channel activity
ND05_RS17340	COG4220	transposase activity
ND05_RS17375	COG3772	lysozyme
ND05_RS17425	COG2207	Transcriptional regulator
ND05_RS17440	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
ND05_RS17445	COG1403	HNH endonuclease
ND05_RS17455	COG3111	PFAM Bacterial OB fold (BOF) protein
ND05_RS17490	COG1846	Transcriptional regulator
ND05_RS17555	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ND05_RS17575	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ND05_RS17600	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ND05_RS17605	COG5301	cellulose 1,4-beta-cellobiosidase activity
ND05_RS17710	COG0740	serine-type endopeptidase activity
ND05_RS17765	COG0582	viral genome integration into host DNA
ND05_RS17790	COG5562	phage envelope protein
ND05_RS17810	COG1278	Cold shock
ND05_RS17820	COG3772	lysozyme
ND05_RS17835	COG1278	Cold shock
ND05_RS17840	COG1278	Cold shock
ND05_RS17850	COG0484	heat shock protein binding
ND05_RS17855	COG1403	HNH endonuclease
ND05_RS17885	COG4372	Transposase
ND05_RS17890	COG3436	PFAM IS66 Orf2 family protein
ND05_RS17895	COG4372	Transposase
ND05_RS17900	COG3436	PFAM IS66 Orf2 family protein
ND05_RS17910	COG1063	alcohol dehydrogenase
ND05_RS17915	COG4948	Mandelate Racemase Muconate Lactonizing
ND05_RS17935	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ND05_RS17950	COG0243	molybdopterin cofactor binding
ND05_RS17955	COG0243	molybdopterin cofactor binding
ND05_RS17960	COG0437	4 iron, 4 sulfur cluster binding
ND05_RS17965	COG3302	dmso reductase anchor subunit
ND05_RS17970	COG3381	protein complex oligomerization
ND05_RS17980	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ND05_RS17985	COG1940	carbohydrate kinase activity
ND05_RS17990	COG0583	DNA-binding transcription factor activity
ND05_RS17995	COG2814	Major facilitator Superfamily
ND05_RS18015	COG3591	Belongs to the peptidase S1B family
ND05_RS18035	COG0628	permease
ND05_RS18040	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ND05_RS18045	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ND05_RS18060	COG0531	amino acid
ND05_RS18070	COG3136	membrane protein required for alginate biosynthesis
ND05_RS18075	COG0745	RESPONSE REGULATOR receiver
ND05_RS18080	COG2205	protein histidine kinase activity
ND05_RS18090	COG0114	fumarate hydratase activity
ND05_RS18095	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ND05_RS18095	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ND05_RS18100	COG1482	cell wall glycoprotein biosynthetic process
ND05_RS18105	COG5339	Protein conserved in bacteria
ND05_RS18120	COG3250	beta-galactosidase activity
ND05_RS18125	COG1309	transcriptional regulator
ND05_RS18130	COG1028	Short-chain dehydrogenase reductase Sdr
ND05_RS18135	COG1609	Transcriptional regulator
ND05_RS18140	COG1263	PTS System
ND05_RS18140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ND05_RS18145	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ND05_RS18155	COG0673	inositol 2-dehydrogenase activity
ND05_RS18200	COG4659	FMN binding
ND05_RS18210	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ND05_RS18220	COG3104	oligopeptide transport
ND05_RS18225	COG0625	glutathione transferase activity
ND05_RS18230	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
ND05_RS18245	COG3895	Periplasmic Protein
ND05_RS18255	COG3133	Outer membrane lipoprotein
ND05_RS18270	COG1566	PFAM secretion protein HlyD family protein
ND05_RS18280	COG2032	superoxide dismutase activity
ND05_RS18285	COG4989	oxidoreductase activity
ND05_RS18290	COG3313	Fe-S protein
ND05_RS18295	COG1309	transcriptional regulator
ND05_RS18300	COG1902	pentaerythritol trinitrate reductase activity
ND05_RS18305	COG0346	lactoylglutathione lyase activity
ND05_RS18315	COG1201	RNA secondary structure unwinding
ND05_RS18320	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ND05_RS18325	COG0791	NLP P60 protein
ND05_RS18330	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ND05_RS18335	COG2814	Major facilitator Superfamily
ND05_RS18355	COG0583	DNA-binding transcription factor activity
ND05_RS18360	COG2814	Major facilitator Superfamily
ND05_RS18365	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ND05_RS18370	COG0307	riboflavin synthase, alpha
ND05_RS18380	COG3468	outer membrane autotransporter barrel domain protein
ND05_RS18400	COG4529	Protein conserved in bacteria
ND05_RS18410	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
ND05_RS18415	COG0437	4 iron, 4 sulfur cluster binding
ND05_RS18425	COG2414	aldehyde ferredoxin oxidoreductase
ND05_RS18430	COG0437	4 iron, 4 sulfur cluster binding
ND05_RS18440	COG0469	pyruvate kinase activity
ND05_RS18445	COG4238	major outer membrane lipoprotein
ND05_RS18450	COG1376	ErfK ybiS ycfS ynhG family protein
ND05_RS18465	COG0719	Fe-S assembly protein
ND05_RS18470	COG0396	ATPase activity
ND05_RS18480	COG0316	Belongs to the HesB IscA family
ND05_RS18490	COG2050	protein possibly involved in aromatic compounds catabolism
ND05_RS18495	COG0247	lactate metabolic process
ND05_RS18495	COG0277	FAD linked oxidase domain protein
ND05_RS18505	COG0628	permease
ND05_RS18520	COG0738	Major facilitator superfamily
ND05_RS18540	COG4670	ketone body catabolic process
ND05_RS18545	COG1960	acyl-CoA dehydrogenase activity
ND05_RS18550	COG2207	Transcriptional regulator
ND05_RS18550	COG1917	Cupin 2, conserved barrel domain protein
ND05_RS18560	COG2086	electron transfer activity
ND05_RS18565	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ND05_RS18570	COG0644	oxidoreductase
ND05_RS18575	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
ND05_RS18580	COG0318	PFAM AMP-dependent synthetase and ligase
ND05_RS18585	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ND05_RS18585	COG0574	Belongs to the PEP-utilizing enzyme family
ND05_RS18600	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ND05_RS18605	COG4256	Hemin uptake protein
ND05_RS18615	COG2200	EAL domain
ND05_RS18620	COG0791	NLP P60 protein
ND05_RS18630	COG0386	Belongs to the glutathione peroxidase family
ND05_RS18690	COG3137	Salt-induced outer membrane protein
ND05_RS18695	COG1105	Belongs to the carbohydrate kinase PfkB family
ND05_RS18705	COG3001	Fructosamine kinase
ND05_RS18715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ND05_RS18720	COG1988	membrane-bound metal-dependent
ND05_RS18725	COG1823	symporter activity
ND05_RS18740	COG0753	catalase activity
ND05_RS18750	COG1486	melibiose metabolic process
ND05_RS18755	COG2169	Transcriptional regulator
ND05_RS18755	COG1917	Cupin 2, conserved barrel domain protein
ND05_RS18760	COG1447	Phosphotransferase system cellobiose-specific component IIA
ND05_RS18765	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ND05_RS18770	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ND05_RS18780	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ND05_RS18790	COG0322	excinuclease ABC activity
ND05_RS18800	COG3678	ATP-independent chaperone mediated protein folding
ND05_RS18835	COG0708	Exodeoxyribonuclease III
ND05_RS18840	COG0398	Pfam SNARE associated Golgi protein
ND05_RS18850	COG0398	Pfam SNARE associated Golgi protein
ND05_RS18855	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ND05_RS18860	COG4134	Bacterial extracellular solute-binding protein
ND05_RS18865	COG4135	transport system, permease component
ND05_RS18870	COG4136	ATPase activity
ND05_RS18875	COG2897	thiosulfate sulfurtransferase activity
ND05_RS18880	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ND05_RS18885	COG0494	nUDIX hydrolase
ND05_RS18895	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ND05_RS18905	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ND05_RS18920	COG0778	Nitroreductase
ND05_RS18930	COG0616	signal peptide processing
ND05_RS18935	COG0252	asparaginase activity
ND05_RS18940	COG1335	isochorismatase
ND05_RS18945	COG2814	Major facilitator Superfamily
ND05_RS18950	COG1349	DNA-binding transcription factor activity
ND05_RS18955	COG0667	Aldo Keto reductase
ND05_RS18960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ND05_RS18965	COG0191	fructose-bisphosphate aldolase activity
ND05_RS18970	COG1063	alcohol dehydrogenase
ND05_RS18975	COG2271	Major facilitator Superfamily
ND05_RS18980	COG1063	alcohol dehydrogenase
ND05_RS18985	COG3139	Protein of unknown function (DUF1315)
ND05_RS18995	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ND05_RS19000	COG0676	glucose-6-phosphate 1-epimerase activity
ND05_RS19005	COG0656	L-ascorbic acid biosynthetic process
ND05_RS19010	COG3713	MltA-interacting MipA family protein
ND05_RS19015	COG2766	serine protein kinase
ND05_RS19025	COG2199	diguanylate cyclase activity
ND05_RS19030	COG2199	diguanylate cyclase activity
ND05_RS19035	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ND05_RS19050	COG2207	Transcriptional regulator
ND05_RS19055	COG2807	transmembrane transport
ND05_RS19065	COG3042	response to heat
ND05_RS19070	COG2203	Gaf domain
ND05_RS19070	COG2199	diguanylate cyclase activity
ND05_RS19085	COG2261	transglycosylase associated protein
ND05_RS19095	COG3615	Tellurite resistance protein tehB
ND05_RS19105	COG0583	DNA-binding transcription factor activity
ND05_RS19110	COG0473	3-isopropylmalate dehydrogenase activity
ND05_RS19115	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ND05_RS19120	COG4638	Rieske (2fe-2S)
ND05_RS19125	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ND05_RS19130	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ND05_RS19135	COG0318	PFAM AMP-dependent synthetase and ligase
ND05_RS19140	COG3065	identical protein binding
ND05_RS19145	COG1214	PFAM Peptidase M22, glycoprotease
ND05_RS19150	COG1199	ATP-dependent helicase activity
ND05_RS19155	COG0251	oxidation-reduction process
ND05_RS19170	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ND05_RS19180	COG1760	l-serine dehydratase
ND05_RS19205	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ND05_RS19205	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ND05_RS19210	COG3715	PTS system
ND05_RS19215	COG3716	PTS system mannose fructose sorbose family IID component
ND05_RS19270	COG1414	Transcriptional regulator
ND05_RS19275	COG2814	Major facilitator Superfamily
ND05_RS19285	COG0793	Belongs to the peptidase S41A family
ND05_RS19295	COG1956	GAF domain-containing protein
ND05_RS19300	COG2995	paraquat-inducible protein a
ND05_RS19305	COG3008	intermembrane lipid transfer
ND05_RS19325	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ND05_RS19335	COG1276	copper resistance
ND05_RS19340	COG2372	response to copper ion
ND05_RS19350	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ND05_RS19355	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ND05_RS19360	COG1770	oligopeptidase
ND05_RS19365	COG2979	Protein of unknown function (DUF533)
ND05_RS19375	COG3141	response to X-ray
ND05_RS19385	COG0800	Aldolase
ND05_RS19390	COG0129	dihydroxy-acid dehydratase activity
ND05_RS19395	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ND05_RS19400	COG1737	Transcriptional regulator
ND05_RS19405	COG0469	pyruvate kinase activity
ND05_RS19410	COG1560	Kdo2-lipid A biosynthetic process
ND05_RS19420	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
ND05_RS19430	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ND05_RS19460	COG0217	transcriptional regulatory protein
ND05_RS19465	COG0494	nUDIX hydrolase
ND05_RS19480	COG1801	Protein of unknown function DUF72
ND05_RS19485	COG3788	relative of glutathione S-transferase, MAPEG superfamily
ND05_RS19500	COG0243	molybdopterin cofactor binding
ND05_RS19505	COG3005	denitrification pathway
ND05_RS19515	COG3102	Protein conserved in bacteria
ND05_RS19535	COG3436	PFAM IS66 Orf2 family protein
ND05_RS19540	COG4372	Transposase
ND05_RS19550	COG3436	PFAM IS66 Orf2 family protein
ND05_RS19555	COG4372	Transposase
ND05_RS19560	COG3755	Protein conserved in bacteria
ND05_RS19575	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ND05_RS19580	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ND05_RS19585	COG0745	RESPONSE REGULATOR receiver
ND05_RS19590	COG2201	protein-glutamate methylesterase activity
ND05_RS19595	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ND05_RS19600	COG0840	transmembrane signaling receptor activity
ND05_RS19605	COG0840	transmembrane signaling receptor activity
ND05_RS19610	COG0835	chemotaxis
ND05_RS19615	COG0643	Histidine kinase
ND05_RS19615	COG2198	Histidine kinase
ND05_RS19620	COG1360	Flagellar Motor Protein
ND05_RS19625	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ND05_RS19640	COG0589	response to stress
ND05_RS19650	COG1877	trehalose-phosphatase activity
ND05_RS19655	COG1172	Belongs to the binding-protein-dependent transport system permease family
ND05_RS19660	COG1129	ABC transporter
ND05_RS19665	COG1879	ABC-type sugar transport system periplasmic component
ND05_RS19675	COG1528	Iron-storage protein
ND05_RS19695	COG1528	Iron-storage protein
ND05_RS19705	COG0814	amino acid
ND05_RS19710	COG3012	SEC-C Motif Domain Protein
ND05_RS19710	COG3318	Belongs to the UPF0149 family
ND05_RS19715	COG4974	Belongs to the 'phage' integrase family
ND05_RS19825	COG4695	Portal protein
ND05_RS19910	COG5301	cellulose 1,4-beta-cellobiosidase activity
ND05_RS19910	COG5301	cellulose 1,4-beta-cellobiosidase activity
ND05_RS19915	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ND05_RS20010	COG2197	response regulator
ND05_RS20025	COG2197	response regulator
ND05_RS20030	COG1126	abc transporter atp-binding protein
ND05_RS20035	COG0765	amino acid transport
ND05_RS20045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ND05_RS20055	COG1191	sigma factor activity
ND05_RS20070	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ND05_RS20075	COG1516	flagellar protein fliS
ND05_RS20085	COG0366	Alpha amylase catalytic
ND05_RS20100	COG2391	methyltransferase activity
ND05_RS20105	COG0425	Belongs to the sulfur carrier protein TusA family
ND05_RS20110	COG2135	peptidase activity
ND05_RS20130	COG1766	The M ring may be actively involved in energy transduction
ND05_RS20135	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ND05_RS20140	COG1317	bacterial-type flagellum organization
ND05_RS20145	COG1157	protein secretion by the type III secretion system
ND05_RS20150	COG2882	bacterial-type flagellum organization
ND05_RS20155	COG3144	bacterial-type flagellum assembly
ND05_RS20160	COG1580	Controls the rotational direction of flagella during chemotaxis
ND05_RS20165	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ND05_RS20170	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ND05_RS20175	COG3190	flagellar
ND05_RS20180	COG1338	Plays a role in the flagellum-specific transport system
ND05_RS20185	COG1987	bacterial-type flagellum assembly
ND05_RS20190	COG1684	flagellar biosynthetic protein fliR
ND05_RS20195	COG2197	response regulator
ND05_RS20230	COG5475	Uncharacterized small protein (DUF2158)
ND05_RS20235	COG2354	Protein conserved in bacteria
ND05_RS20240	COG0697	spore germination
ND05_RS20245	COG3727	T/G mismatch-specific endonuclease activity
ND05_RS20250	COG0270	DNA (cytosine-5-)-methyltransferase activity
ND05_RS20255	COG1418	mRNA catabolic process
ND05_RS20265	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ND05_RS20280	COG2205	protein histidine kinase activity
ND05_RS20285	COG0745	RESPONSE REGULATOR receiver
ND05_RS20290	COG2351	hydroxyisourate hydrolase activity
ND05_RS20305	COG3443	Belongs to the bacterial solute-binding protein 9 family
ND05_RS20310	COG3038	cytochrome b561
ND05_RS20395	COG1470	cell adhesion involved in biofilm formation
ND05_RS20395	COG1388	LysM domain
ND05_RS20415	COG0477	Major facilitator Superfamily
ND05_RS20420	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ND05_RS20425	COG0217	transcriptional regulatory protein
ND05_RS20445	COG0534	Mate efflux family protein
ND05_RS20455	COG0582	viral genome integration into host DNA
ND05_RS20495	COG0583	DNA-binding transcription factor activity
ND05_RS20500	COG0583	DNA-binding transcription factor activity
ND05_RS20510	COG1376	ErfK ybiS ycfS ynhG family protein
ND05_RS20525	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
ND05_RS20585	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
ND05_RS20600	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
ND05_RS20615	COG1012	belongs to the aldehyde dehydrogenase family
ND05_RS20615	COG1454	alcohol dehydrogenase
ND05_RS20620	COG4656	Part of a membrane complex involved in electron transport
ND05_RS20645	COG1289	transmembrane transporter activity
ND05_RS20655	COG1686	Belongs to the peptidase S11 family
ND05_RS20660	COG2925	Exonuclease
ND05_RS20665	COG0425	Belongs to the sulfur carrier protein TusA family
ND05_RS20670	COG2391	methyltransferase activity
ND05_RS20675	COG0531	amino acid
ND05_RS20685	COG0583	DNA-binding transcription factor activity
ND05_RS20690	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ND05_RS20695	COG4115	mRNA cleavage
ND05_RS20700	COG2161	toxin-antitoxin pair type II binding
ND05_RS20720	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ND05_RS20730	COG0131	Imidazoleglycerol-phosphate dehydratase
ND05_RS20730	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ND05_RS20735	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ND05_RS20755	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
ND05_RS20760	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ND05_RS20765	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ND05_RS20770	COG0438	transferase activity, transferring glycosyl groups
ND05_RS20775	COG0438	transferase activity, transferring glycosyl groups
ND05_RS20780	COG0367	asparagine synthase
ND05_RS20795	COG1215	transferase activity, transferring glycosyl groups
ND05_RS20820	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ND05_RS20835	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ND05_RS20840	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ND05_RS20850	COG0438	transferase activity, transferring glycosyl groups
ND05_RS20855	COG2327	Polysaccharide pyruvyl transferase
ND05_RS20860	COG2244	polysaccharide biosynthetic process
ND05_RS20865	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ND05_RS20870	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ND05_RS20875	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
ND05_RS20875	COG0662	Cupin 2, conserved barrel domain protein
ND05_RS20880	COG0297	glycogen (starch) synthase activity
ND05_RS20885	COG1051	belongs to the nudix hydrolase family
ND05_RS20890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ND05_RS20895	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
ND05_RS20900	COG0110	maltose O-acetyltransferase activity
ND05_RS20905	COG1216	Glycosyl transferase, family 2
ND05_RS20915	COG0438	transferase activity, transferring glycosyl groups
ND05_RS20920	COG1045	serine acetyltransferase
ND05_RS20925	COG0463	Glycosyl transferase, family 2
ND05_RS20930	COG0489	protein tyrosine kinase activity
ND05_RS20930	COG3206	protein involved in exopolysaccharide biosynthesis
ND05_RS20935	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ND05_RS20940	COG1596	polysaccharide export
ND05_RS20945	COG1253	flavin adenine dinucleotide binding
ND05_RS20950	COG2982	Protein involved in outer membrane biogenesis
ND05_RS20960	COG0572	uridine kinase
ND05_RS20965	COG3447	MASE1 domain protein
ND05_RS20965	COG5001	Diguanylate cyclase
ND05_RS20965	COG5002	protein histidine kinase activity
ND05_RS20970	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ND05_RS20975	COG0443	Heat shock 70 kDa protein
ND05_RS20980	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
ND05_RS20985	COG3779	Protein conserved in bacteria
ND05_RS20990	COG0631	protein serine/threonine phosphatase activity
ND05_RS20995	COG4245	von Willebrand factor, type A
ND05_RS21040	COG2205	protein histidine kinase activity
ND05_RS21045	COG0745	RESPONSE REGULATOR receiver
ND05_RS21055	COG3609	addiction module antidote protein, CC2985 family
ND05_RS21065	COG0826	peptidase U32
ND05_RS21090	COG1063	alcohol dehydrogenase
ND05_RS21095	COG3775	system Galactitol-specific IIC component
ND05_RS21100	COG3414	Phosphotransferase system galactitol-specific IIB component
ND05_RS21105	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ND05_RS21120	COG1830	Aldolase
ND05_RS21125	COG2211	Major facilitator Superfamily
ND05_RS21130	COG1397	ADP-ribosylglycohydrolase
ND05_RS21135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ND05_RS21140	COG2188	Transcriptional regulator
ND05_RS21145	COG3757	hydrolase, family 25
ND05_RS21150	COG0351	phosphomethylpyrimidine kinase
ND05_RS21165	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ND05_RS21170	COG5455	response to cobalt ion
ND05_RS21175	COG3539	Fimbrial protein
ND05_RS21180	COG3188	usher protein
ND05_RS21185	COG3121	Chaperone
ND05_RS21190	COG3539	Fimbrial protein
ND05_RS21205	COG0489	protein tyrosine kinase activity
ND05_RS21215	COG3831	ATPase activity
ND05_RS21225	COG3831	ATPase activity
ND05_RS21240	COG0714	Associated with various cellular activities
ND05_RS21245	COG2425	protein containing a von Willebrand factor type A (vWA) domain
ND05_RS21250	COG3552	Protein containing von Willebrand factor type A (VWA) domain
ND05_RS21255	COG4715	Zinc finger, swim domain protein
ND05_RS21260	COG4808	Protein conserved in bacteria
ND05_RS21265	COG4807	Protein conserved in bacteria
ND05_RS21270	COG3279	Response regulator of the LytR AlgR family
ND05_RS21275	COG3275	phosphorelay sensor kinase activity
ND05_RS21280	COG0789	Transcriptional regulator
ND05_RS21290	COG1174	glycine betaine transport
ND05_RS21295	COG1125	glycine betaine transport
ND05_RS21300	COG1174	glycine betaine transport
ND05_RS21305	COG1732	Glycine betaine
ND05_RS21310	COG1472	Belongs to the glycosyl hydrolase 3 family
ND05_RS21315	COG0277	FAD linked oxidase domain protein
ND05_RS21320	COG1686	Belongs to the peptidase S11 family
ND05_RS21330	COG0586	Pfam SNARE associated Golgi protein
ND05_RS21335	COG1028	Short-chain dehydrogenase reductase Sdr
ND05_RS21360	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ND05_RS21370	COG1346	cytolysis
ND05_RS21380	COG2949	membrane
ND05_RS21390	COG0493	'glutamate synthase
ND05_RS21395	COG0167	dihydroorotate dehydrogenase activity
ND05_RS21395	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ND05_RS21400	COG4211	Belongs to the binding-protein-dependent transport system permease family
ND05_RS21405	COG1129	ABC transporter
ND05_RS21410	COG1879	ABC-type sugar transport system periplasmic component
ND05_RS21415	COG1609	Transcriptional regulator
ND05_RS21425	COG2311	Membrane
ND05_RS21450	COG4771	TonB-dependent receptor
ND05_RS21460	COG0833	amino acid
ND05_RS21470	COG0583	DNA-binding transcription factor activity
ND05_RS21475	COG2855	membrane
ND05_RS21485	COG1522	sequence-specific DNA binding
ND05_RS21485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ND05_RS21490	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ND05_RS21500	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ND05_RS21505	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ND05_RS21510	COG2313	pseudouridylate synthase activity
ND05_RS21515	COG2313	pseudouridylate synthase activity
ND05_RS21520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ND05_RS21525	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ND05_RS21525	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
ND05_RS21525	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ND05_RS21530	COG1105	Belongs to the carbohydrate kinase PfkB family
ND05_RS21535	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ND05_RS21535	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ND05_RS21540	COG2814	Major facilitator Superfamily
ND05_RS21555	COG0246	Mannitol dehydrogenase
ND05_RS21560	COG0523	cobalamin synthesis protein
ND05_RS21565	COG0671	phosphoesterase, PA-phosphatase related
ND05_RS21570	COG0791	NLP P60 protein
ND05_RS21575	COG2200	EAL domain
ND05_RS21580	COG4166	transmembrane transport
ND05_RS21585	COG4174	ABC transporter (Permease)
ND05_RS21590	COG4239	(ABC) transporter, permease
ND05_RS21595	COG4172	Belongs to the ABC transporter superfamily
ND05_RS21610	COG2814	Major facilitator Superfamily
ND05_RS21615	COG1187	pseudouridine synthase activity
ND05_RS21625	COG1061	Type III restriction enzyme res subunit
ND05_RS21645	COG3083	sulfuric ester hydrolase activity
ND05_RS21660	COG3468	outer membrane autotransporter barrel domain protein
ND05_RS21670	COG2197	response regulator
ND05_RS21675	COG4235	cytochrome complex assembly
ND05_RS21675	COG3088	subunit of a heme lyase
ND05_RS21680	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ND05_RS21685	COG1138	Cytochrome C-type biogenesis protein
ND05_RS21695	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ND05_RS21700	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ND05_RS21705	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ND05_RS21715	COG3005	denitrification pathway
ND05_RS21720	COG3043	anaerobic respiration
ND05_RS21725	COG0348	domain, Protein
ND05_RS21730	COG0437	4 iron, 4 sulfur cluster binding
ND05_RS21740	COG3062	negative regulation of establishment of protein localization
ND05_RS21745	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ND05_RS21745	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
ND05_RS21765	COG4615	Cyclic peptide transporter
ND05_RS21770	COG3145	DNA-N1-methyladenine dioxygenase activity
ND05_RS21775	COG2169	Transcriptional regulator
ND05_RS21775	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ND05_RS21780	COG1477	protein flavinylation
ND05_RS21785	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ND05_RS21800	COG2198	Histidine kinase
ND05_RS21800	COG0642	Histidine kinase
ND05_RS21805	COG2197	response regulator
ND05_RS21810	COG0784	Response regulator, receiver
ND05_RS21810	COG2205	protein histidine kinase activity
ND05_RS21815	COG3852	Histidine kinase
ND05_RS21820	COG2204	response regulator
ND05_RS21825	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ND05_RS21830	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ND05_RS21835	COG2031	fatty acid transporter
ND05_RS21840	COG0183	Belongs to the thiolase family
ND05_RS21845	COG4676	Protein conserved in bacteria
ND05_RS21850	COG5445	Predicted secreted protein (DUF2300)
ND05_RS21855	COG2373	Large extracellular alpha-helical protein
ND05_RS21860	COG3234	Protein of unknown function (DUF1175)
ND05_RS21865	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
ND05_RS21870	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ND05_RS21880	COG3468	outer membrane autotransporter barrel domain protein
ND05_RS21890	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ND05_RS21895	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ND05_RS21900	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ND05_RS21905	COG3642	lipopolysaccharide core region biosynthetic process
ND05_RS21910	COG0583	DNA-binding transcription factor activity
ND05_RS21915	COG0584	glycerophosphoryl diester phosphodiesterase
ND05_RS21920	COG2271	Major facilitator Superfamily
ND05_RS21925	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ND05_RS21935	COG0247	lactate metabolic process
ND05_RS21940	COG5464	transposase or invertase
ND05_RS21945	COG3836	Belongs to the HpcH HpaI aldolase family
ND05_RS21950	COG2271	Major facilitator Superfamily
ND05_RS21960	COG1414	Transcriptional regulator
ND05_RS22025	COG0318	PFAM AMP-dependent synthetase and ligase
ND05_RS22035	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ND05_RS22050	COG1169	isochorismate synthase
ND05_RS22055	COG4575	ribosome binding
ND05_RS22060	COG2153	protein acetylation
ND05_RS22090	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ND05_RS22095	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ND05_RS22105	COG0839	Belongs to the complex I subunit 6 family
ND05_RS22120	COG1034	ATP synthesis coupled electron transport
ND05_RS22125	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ND05_RS22130	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ND05_RS22150	COG0583	DNA-binding transcription factor activity
ND05_RS22160	COG0436	Aminotransferase
ND05_RS22170	COG0471	metal ion transport
ND05_RS22170	COG0490	domain, Protein
ND05_RS22175	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ND05_RS22190	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ND05_RS22195	COG0280	phosphate acetyltransferase
ND05_RS22195	COG0857	belongs to the CobB CobQ family
ND05_RS22200	COG1288	antiporter activity
ND05_RS22205	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
ND05_RS22210	COG0622	Phosphoesterase
ND05_RS22215	COG0625	glutathione transferase activity
ND05_RS22220	COG0625	glutathione transferase activity
ND05_RS22225	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ND05_RS22230	COG1090	epimerase
ND05_RS22235	COG5464	transposase or invertase
ND05_RS22240	COG4598	ABC transporter
ND05_RS22245	COG4160	amino acid transport
ND05_RS22250	COG4215	(ABC) transporter
ND05_RS22255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ND05_RS22260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ND05_RS22265	COG0163	prenyltransferase activity
ND05_RS22270	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ND05_RS22275	COG1286	toxin biosynthetic process
ND05_RS22280	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
ND05_RS22285	COG0285	dihydrofolate synthase activity
ND05_RS22295	COG0586	Pfam SNARE associated Golgi protein
ND05_RS22305	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ND05_RS22320	COG2814	Major facilitator Superfamily
ND05_RS22330	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ND05_RS22345	COG3101	peptidyl-lysine hydroxylation
ND05_RS22350	COG0730	response to heat
ND05_RS22365	COG2890	protein-(glutamine-N5) methyltransferase activity
ND05_RS22380	COG3539	Fimbrial protein
ND05_RS22385	COG3539	Fimbrial protein
ND05_RS22390	COG3539	Fimbrial protein
ND05_RS22395	COG3121	Chaperone
ND05_RS22405	COG3539	Fimbrial protein
ND05_RS22410	COG2062	phosphohistidine phosphatase, SixA
ND05_RS22425	COG3691	Protein conserved in bacteria
ND05_RS22435	COG2067	long-chain fatty acid transport protein
ND05_RS22450	COG2853	Lipoprotein
ND05_RS22460	COG2116	formate transmembrane transporter activity
ND05_RS22625	COG3772	lysozyme
ND05_RS22955	COG0583	DNA-binding transcription factor activity
ND05_RS22960	COG2610	gluconate transmembrane transporter activity
ND05_RS22970	COG0477	Major facilitator Superfamily
ND05_RS22975	COG1566	PFAM secretion protein HlyD family protein
ND05_RS22980	COG2197	response regulator
ND05_RS22985	COG2205	protein histidine kinase activity
ND05_RS22985	COG2198	Histidine kinase
ND05_RS22985	COG0784	Response regulator, receiver
ND05_RS22985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ND05_RS22990	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ND05_RS22995	COG0679	Auxin Efflux Carrier
ND05_RS23000	COG0028	Belongs to the TPP enzyme family
ND05_RS23030	COG1560	Kdo2-lipid A biosynthetic process
ND05_RS23040	COG0436	Aminotransferase
ND05_RS23045	COG3275	phosphorelay sensor kinase activity
ND05_RS23050	COG3279	Response regulator of the LytR AlgR family
ND05_RS23055	COG2207	Transcriptional regulator
ND05_RS23065	COG1363	Peptidase, m42
ND05_RS23070	COG0006	proline dipeptidase activity
ND05_RS23075	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ND05_RS23080	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ND05_RS23105	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ND05_RS23110	COG2199	diguanylate cyclase activity
ND05_RS23110	COG2200	EAL domain
ND05_RS23125	COG3415	Transposase
ND05_RS23130	COG3415	Transposase
ND05_RS23160	COG0583	DNA-binding transcription factor activity
ND05_RS23170	COG3530	Putative quorum-sensing-regulated virulence factor
ND05_RS23190	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ND05_RS23195	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ND05_RS23200	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ND05_RS23205	COG2190	(PTS) system
ND05_RS23220	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ND05_RS23225	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ND05_RS23230	COG4208	sulfate ABC transporter
ND05_RS23235	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ND05_RS23240	COG4150	thiosulfate binding
ND05_RS23250	COG1028	Short-chain dehydrogenase reductase Sdr
ND05_RS23265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ND05_RS23265	COG1263	PTS System
ND05_RS23270	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ND05_RS23275	COG2837	iron assimilation
ND05_RS23295	COG0860	N-Acetylmuramoyl-L-alanine amidase
ND05_RS23305	COG2207	Transcriptional regulator
ND05_RS23310	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
ND05_RS23315	COG4816	utilization protein
ND05_RS23325	COG4303	Ethanolamine ammonia lyase large subunit
ND05_RS23330	COG4819	ethanolamine utilization protein
ND05_RS23335	COG3192	ethanolamine utilization protein
ND05_RS23340	COG1454	alcohol dehydrogenase
ND05_RS23345	COG4820	ethanolamine utilization protein (EutJ)
ND05_RS23350	COG1012	belongs to the aldehyde dehydrogenase family
ND05_RS23355	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
ND05_RS23360	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
ND05_RS23365	COG0280	phosphate acetyltransferase
ND05_RS23370	COG4812	Cobalamin adenosyltransferase
ND05_RS23375	COG4766	ethanolamine catabolic process
ND05_RS23380	COG4917	ethanolamine utilization protein
ND05_RS23385	COG4810	utilization protein
ND05_RS23395	COG0280	phosphate acetyltransferase
ND05_RS23395	COG0281	malic enzyme
ND05_RS23400	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ND05_RS23405	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ND05_RS23410	COG5342	invasion associated locus B
ND05_RS23420	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ND05_RS23420	COG0493	'glutamate synthase
ND05_RS23425	COG3850	Histidine kinase
ND05_RS23430	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ND05_RS23445	COG1393	Belongs to the ArsC family
ND05_RS23465	COG1444	tRNA N-acetyltransferase activity
ND05_RS23470	COG2321	neutral zinc metallopeptidase
ND05_RS23490	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
ND05_RS23500	COG2716	regulation of RNA biosynthetic process
ND05_RS23505	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ND05_RS23510	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ND05_RS23520	COG0650	Formate hydrogenlyase subunit 4
ND05_RS23525	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ND05_RS23535	COG4237	Hydrogenase 4 membrane
ND05_RS23540	COG0651	ATP synthesis coupled electron transport
ND05_RS23545	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
ND05_RS23545	COG3261	NADH dehydrogenase
ND05_RS23550	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ND05_RS23555	COG3260	NADH ubiquinone oxidoreductase 20
ND05_RS23565	COG3604	Transcriptional regulator
ND05_RS23570	COG2116	formate transmembrane transporter activity
ND05_RS23580	COG0628	permease
ND05_RS23585	COG4783	chaperone-mediated protein folding
ND05_RS23590	COG1393	Belongs to the ArsC family
ND05_RS23600	COG2233	PERMEase
ND05_RS23620	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ND05_RS23625	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ND05_RS23630	COG0248	Ppx GppA phosphatase
ND05_RS23635	COG2200	EAL domain
ND05_RS23655	COG3133	Outer membrane lipoprotein
ND05_RS23670	COG0517	IMP dehydrogenase activity
ND05_RS23670	COG0516	GMP reductase activity
ND05_RS23680	COG1645	bacterial-type flagellum-dependent swarming motility
ND05_RS23695	COG2976	Protein conserved in bacteria
ND05_RS23730	COG4953	penicillin-binding protein 1C
ND05_RS23735	COG2373	Large extracellular alpha-helical protein
ND05_RS23740	COG2897	thiosulfate sulfurtransferase activity
ND05_RS23755	COG2975	iron-sulfur cluster assembly
ND05_RS23760	COG0633	Ferredoxin
ND05_RS23780	COG0822	iron-sulfur transferase activity
ND05_RS23800	COG0483	inositol monophosphate 1-phosphatase activity
ND05_RS23805	COG1073	alpha beta
ND05_RS23810	COG3711	transcriptional antiterminator
ND05_RS23815	COG2814	Major facilitator Superfamily
ND05_RS23820	COG0583	DNA-binding transcription factor activity
ND05_RS23825	COG4638	Rieske (2fe-2S)
ND05_RS23850	COG2259	Doxx family
ND05_RS23855	COG2017	converts alpha-aldose to the beta-anomer
ND05_RS23860	COG1063	alcohol dehydrogenase
ND05_RS23865	COG1172	Belongs to the binding-protein-dependent transport system permease family
ND05_RS23870	COG1129	ABC transporter
ND05_RS23875	COG1879	ABC-type sugar transport system periplasmic component
ND05_RS23880	COG0457	Tetratricopeptide repeat
ND05_RS23885	COG1940	carbohydrate kinase activity
ND05_RS23895	COG1017	nitric oxide dioxygenase activity
ND05_RS23895	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ND05_RS23900	COG0347	Belongs to the P(II) protein family
ND05_RS23905	COG2204	response regulator
ND05_RS23910	COG3170	Tfp pilus assembly protein FimV
ND05_RS23915	COG2205	protein histidine kinase activity
ND05_RS23920	COG0047	phosphoribosylformylglycinamidine synthase activity
ND05_RS23920	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ND05_RS23935	COG0560	Phosphoserine phosphatase
ND05_RS23940	COG1737	Transcriptional regulator
ND05_RS23945	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ND05_RS23970	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ND05_RS24005	COG3086	response to oxidative stress
ND05_RS24010	COG3026	antisigma factor binding
ND05_RS24015	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
ND05_RS24020	COG1595	DNA-templated transcription, initiation
ND05_RS24025	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ND05_RS24035	COG0513	Belongs to the DEAD box helicase family
ND05_RS24040	COG0583	DNA-binding transcription factor activity
ND05_RS24060	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ND05_RS24070	COG3118	belongs to the thioredoxin family
ND05_RS24075	COG3148	PFAM DTW domain containing protein
ND05_RS24080	COG1042	CoA-binding domain protein
ND05_RS24080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ND05_RS24080	COG0045	succinate-CoA ligase (ADP-forming) activity
ND05_RS24085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ND05_RS24090	COG5544	Lipoprotein
ND05_RS24095	COG0477	Major facilitator Superfamily
ND05_RS24125	COG0542	response to heat
ND05_RS24135	COG0564	pseudouridine synthase activity
ND05_RS24140	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ND05_RS24150	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ND05_RS24160	COG1605	Chorismate mutase
ND05_RS24160	COG0077	Prephenate dehydratase
ND05_RS24165	COG0287	Prephenate dehydrogenase
ND05_RS24165	COG1605	Chorismate mutase
ND05_RS24170	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ND05_RS24190	COG2885	chlorophyll binding
ND05_RS24215	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ND05_RS24220	COG4137	Cytochrome C assembly protein
ND05_RS24225	COG4536	flavin adenine dinucleotide binding
ND05_RS24245	COG0497	DNA recombination
ND05_RS24250	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ND05_RS24260	COG2867	negative regulation of translational initiation
ND05_RS24295	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ND05_RS24300	COG5301	cellulose 1,4-beta-cellobiosidase activity
ND05_RS24375	COG0740	serine-type endopeptidase activity
ND05_RS24410	COG3772	lysozyme
ND05_RS24420	COG2189	Belongs to the N(4) N(6)-methyltransferase family
ND05_RS24435	COG0484	heat shock protein binding
ND05_RS24465	COG1846	Transcriptional regulator
ND05_RS24475	COG3646	Phage regulatory protein
ND05_RS24515	COG5532	Uncharacterized conserved protein (DUF2303)
ND05_RS24520	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
ND05_RS24540	COG0582	viral genome integration into host DNA
ND05_RS24585	COG5301	cellulose 1,4-beta-cellobiosidase activity
ND05_RS24600	COG2032	superoxide dismutase activity
ND05_RS24720	COG3772	lysozyme
ND05_RS24855	COG4974	Belongs to the 'phage' integrase family
ND05_RS24905	COG0366	Alpha amylase catalytic
ND05_RS24915	COG0579	oxidoreductase
ND05_RS24920	COG1012	belongs to the aldehyde dehydrogenase family
ND05_RS24925	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ND05_RS24930	COG1113	amino acid transport
ND05_RS24935	COG1802	Transcriptional regulator
ND05_RS24940	COG1652	LysM domain
ND05_RS24945	COG0401	homolog of Blt101
ND05_RS24950	COG0640	Transcriptional regulator
ND05_RS24955	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ND05_RS24960	COG2916	Histone family protein nucleoid-structuring protein H-NS
ND05_RS24975	COG4575	ribosome binding
ND05_RS24980	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ND05_RS24990	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ND05_RS24995	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ND05_RS25000	COG4175	Glycine betaine
ND05_RS25005	COG4176	ABC-type proline glycine betaine transport system permease component
ND05_RS25010	COG2113	Glycine betaine
ND05_RS25015	COG2814	Major facilitator Superfamily
ND05_RS25020	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ND05_RS25030	COG1846	Transcriptional regulator
ND05_RS25035	COG1566	PFAM secretion protein HlyD family protein
ND05_RS25040	COG2814	Major facilitator Superfamily
ND05_RS25055	COG1238	metal cluster binding
ND05_RS25060	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ND05_RS25090	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ND05_RS25110	COG1546	Belongs to the CinA family
ND05_RS25115	COG2951	lytic endotransglycosylase activity
ND05_RS25120	COG3730	PTS system glucitol sorbitol-specific
ND05_RS25125	COG3732	PTS system glucitol sorbitol-specific
ND05_RS25135	COG1028	Short-chain dehydrogenase reductase Sdr
ND05_RS25140	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
ND05_RS25145	COG1349	DNA-binding transcription factor activity
ND05_RS25170	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ND05_RS25175	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ND05_RS25180	COG1609	Transcriptional regulator
ND05_RS25185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ND05_RS25185	COG1263	PTS System
ND05_RS25190	COG2723	6-phospho-beta-galactosidase activity
ND05_RS25195	COG5499	transcription regulator containing HTH domain
ND05_RS25200	COG4680	protein conserved in bacteria
ND05_RS25210	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ND05_RS25220	COG3260	NADH ubiquinone oxidoreductase 20
ND05_RS25225	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ND05_RS25230	COG3261	NADH dehydrogenase
ND05_RS25230	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
ND05_RS25235	COG0650	Formate hydrogenlyase subunit 4
ND05_RS25240	COG0651	ATP synthesis coupled electron transport
ND05_RS25245	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ND05_RS25255	COG0375	protein maturation
ND05_RS25260	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ND05_RS25265	COG0298	carbon dioxide binding
ND05_RS25270	COG0409	Hydrogenase expression formation protein
ND05_RS25275	COG0309	Hydrogenase expression formation protein (HypE)
ND05_RS25280	COG3604	Transcriptional regulator
ND05_RS25295	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ND05_RS25300	COG1349	DNA-binding transcription factor activity
ND05_RS25305	COG2084	Dehydrogenase
ND05_RS25310	COG3395	kinase activity
ND05_RS25315	COG0235	Class ii aldolase
ND05_RS25320	COG3622	Belongs to the hyi family
ND05_RS25325	COG2610	gluconate transmembrane transporter activity
ND05_RS25335	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ND05_RS25350	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ND05_RS25355	COG1388	LysM domain
ND05_RS25355	COG4942	peptidase
ND05_RS25410	COG2234	aminopeptidase activity
ND05_RS25415	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ND05_RS25420	COG1518	maintenance of DNA repeat elements
ND05_RS25435	COG1857	crispr-associated protein
ND05_RS25480	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ND05_RS25490	COG0720	synthase
ND05_RS25495	COG0644	oxidoreductase
ND05_RS25500	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
ND05_RS25505	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
ND05_RS25510	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ND05_RS25515	COG2086	electron transfer activity
ND05_RS25520	COG0477	Major facilitator Superfamily
ND05_RS25525	COG0277	FAD linked oxidase domain protein
ND05_RS25530	COG1028	Short-chain dehydrogenase reductase Sdr
ND05_RS25535	COG2223	nitrite transmembrane transporter activity
ND05_RS25540	COG1070	Carbohydrate kinase
ND05_RS25545	COG0602	queuosine metabolic process
ND05_RS25570	COG3956	TIGRFAM MazG family protein
ND05_RS25575	COG2337	Toxic component of a toxin-antitoxin (TA) module
ND05_RS25580	COG2336	PFAM SpoVT AbrB
ND05_RS25585	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ND05_RS25595	COG2205	protein histidine kinase activity
ND05_RS25595	COG3437	response regulator, receiver
ND05_RS25595	COG3850	Histidine kinase
ND05_RS25595	COG4999	Histidine kinase
ND05_RS25600	COG4948	Mandelate Racemase Muconate Lactonizing
ND05_RS25605	COG4948	Mandelate Racemase Muconate Lactonizing
ND05_RS25610	COG2271	Major facilitator Superfamily
ND05_RS25615	COG0716	FMN binding
ND05_RS25620	COG0564	pseudouridine synthase activity
ND05_RS25625	COG3098	single-species biofilm formation
ND05_RS25640	COG1611	Belongs to the LOG family
ND05_RS25645	COG0814	amino acid
ND05_RS25650	COG1760	l-serine dehydratase
ND05_RS25660	COG1454	alcohol dehydrogenase
ND05_RS25665	COG0235	Class ii aldolase
ND05_RS25670	COG0738	Major facilitator superfamily
ND05_RS25680	COG1070	Carbohydrate kinase
ND05_RS25690	COG1349	DNA-binding transcription factor activity
ND05_RS25700	COG2363	Small membrane protein
ND05_RS25705	COG0583	DNA-binding transcription factor activity
ND05_RS25715	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ND05_RS25720	COG2166	iron-sulfur cluster assembly
ND05_RS25725	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ND05_RS25730	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ND05_RS25755	COG0860	N-Acetylmuramoyl-L-alanine amidase
ND05_RS25765	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ND05_RS25765	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ND05_RS25770	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ND05_RS25775	COG1074	ATP-dependent DNA helicase activity
ND05_RS25785	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ND05_RS25790	COG4967	type IV pilus modification protein PilV
ND05_RS25800	COG4795	General secretion pathway protein
ND05_RS25805	COG2165	general secretion pathway protein
ND05_RS25820	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
ND05_RS25835	COG0861	Integral membrane protein TerC family
ND05_RS25845	COG0667	Aldo Keto reductase
ND05_RS25860	COG1609	Transcriptional regulator
ND05_RS25870	COG0583	DNA-binding transcription factor activity
ND05_RS25875	COG1794	racemase activity, acting on amino acids and derivatives
ND05_RS25880	COG2814	Major facilitator Superfamily
ND05_RS25885	COG1028	Short-chain dehydrogenase reductase Sdr
ND05_RS25895	COG0183	Belongs to the thiolase family
ND05_RS25900	COG0814	amino acid
ND05_RS25920	COG4942	peptidase
ND05_RS25930	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ND05_RS25935	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ND05_RS25940	COG2080	2 iron, 2 sulfur cluster binding
ND05_RS25945	COG3829	transcription factor binding
ND05_RS25950	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ND05_RS25955	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ND05_RS25960	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ND05_RS25970	COG0549	Belongs to the carbamate kinase family
ND05_RS25975	COG3608	succinylglutamate desuccinylase aspartoacylase
ND05_RS25975	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ND05_RS25980	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ND05_RS25985	COG2068	MobA-Related Protein
ND05_RS25990	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ND05_RS25990	COG0493	'glutamate synthase
ND05_RS25995	COG0402	S-adenosylhomocysteine deaminase activity
ND05_RS26000	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ND05_RS26005	COG2080	2 iron, 2 sulfur cluster binding
ND05_RS26005	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ND05_RS26010	COG2233	PERMEase
ND05_RS26015	COG0402	S-adenosylhomocysteine deaminase activity
ND05_RS26020	COG2252	PERMEase
ND05_RS26025	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ND05_RS26030	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ND05_RS26030	COG0493	'glutamate synthase
ND05_RS26040	COG2233	PERMEase
ND05_RS26065	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ND05_RS26070	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ND05_RS26075	COG4974	Belongs to the 'phage' integrase family
ND05_RS26080	COG0716	FMN binding
ND05_RS26090	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ND05_RS26100	COG1272	protein, Hemolysin III
ND05_RS26110	COG2723	6-phospho-beta-galactosidase activity
ND05_RS26115	COG1028	Short-chain dehydrogenase reductase Sdr
ND05_RS26135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ND05_RS26140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ND05_RS26145	COG0006	proline dipeptidase activity
ND05_RS26170	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ND05_RS26190	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ND05_RS26210	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ND05_RS26210	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ND05_RS26215	COG1703	isobutyryl-CoA mutase activity
ND05_RS26220	COG1024	Enoyl-CoA hydratase
ND05_RS26225	COG0427	acetyl-CoA hydrolase
ND05_RS26230	COG0583	DNA-binding transcription factor activity
ND05_RS26235	COG2968	Membrane
ND05_RS26245	COG0668	transmembrane transport
ND05_RS26255	COG0191	fructose-bisphosphate aldolase activity
ND05_RS26290	COG1122	ATPase activity
ND05_RS26295	COG1122	ATPase activity
ND05_RS26300	COG1072	(Pantothenic acid kinase))
ND05_RS26310	COG1494	fructose-1,6-bisphosphatase
ND05_RS26315	COG1063	alcohol dehydrogenase
ND05_RS26320	COG2213	PTS system mannitol-specific
ND05_RS26325	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ND05_RS26330	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ND05_RS26335	COG0501	Belongs to the peptidase M48B family
ND05_RS26350	COG1166	arginine decarboxylase activity
ND05_RS26375	COG2814	Major facilitator Superfamily
ND05_RS26385	COG2356	endonuclease I
ND05_RS26390	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ND05_RS26395	COG0189	ligase activity
ND05_RS26410	COG2805	Type II/IV secretion system protein
ND05_RS26415	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ND05_RS26420	COG0762	integral membrane protein
ND05_RS26435	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ND05_RS26440	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ND05_RS26445	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ND05_RS26460	COG0252	asparaginase activity
ND05_RS26470	COG3171	Protein conserved in bacteria
ND05_RS26485	COG1194	a g-specific adenine glycosylase
ND05_RS26500	COG2211	Major facilitator Superfamily
ND05_RS26505	COG1982	Orn Lys Arg decarboxylase major
ND05_RS26515	COG1811	Na channel or pump
ND05_RS26525	COG0582	viral genome integration into host DNA
ND05_RS26530	COG4372	Transposase
ND05_RS26540	COG3436	PFAM IS66 Orf2 family protein
ND05_RS26545	COG4372	Transposase
ND05_RS26570	COG3436	PFAM IS66 Orf2 family protein
ND05_RS26580	COG2003	Belongs to the UPF0758 family
ND05_RS26610	COG4372	Transposase
ND05_RS26615	COG3436	PFAM IS66 Orf2 family protein
ND05_RS26900	COG2003	Belongs to the UPF0758 family
ND05_RS26935	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
ND05_RS26965	COG2165	general secretion pathway protein
ND05_RS26970	COG1459	type II secretion system
ND05_RS26975	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ND05_RS26995	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ND05_RS27010	COG1620	l-lactate permease
ND05_RS27015	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ND05_RS27020	COG3193	protein, possibly involved in utilization of glycolate and propanediol
ND05_RS27025	COG0247	lactate metabolic process
ND05_RS27030	COG0277	FAD linked oxidase domain protein
ND05_RS27035	COG0277	FAD linked oxidase domain protein
ND05_RS27040	COG2186	Transcriptional regulator
ND05_RS27045	COG0456	acetyltransferase
ND05_RS27055	COG0318	PFAM AMP-dependent synthetase and ligase
ND05_RS27095	COG0795	lipopolysaccharide-transporting ATPase activity
ND05_RS27100	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
ND05_RS27110	COG2244	polysaccharide biosynthetic process
ND05_RS27115	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ND05_RS27120	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ND05_RS27125	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ND05_RS27130	COG0306	phosphate transporter
ND05_RS27135	COG0754	glutathionylspermidine amidase activity
ND05_RS27140	COG0625	glutathione transferase activity
ND05_RS27145	COG0298	carbon dioxide binding
ND05_RS27155	COG1773	rubredoxin
ND05_RS27160	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ND05_RS27165	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
ND05_RS27170	COG5557	Pfam Polysulphide reductase, NrfD
ND05_RS27175	COG0437	4 iron, 4 sulfur cluster binding
ND05_RS27180	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
ND05_RS27200	COG0667	Aldo Keto reductase
ND05_RS27210	COG1028	Short-chain dehydrogenase reductase Sdr
ND05_RS27215	COG0848	biopolymer transport protein
ND05_RS27220	COG0811	peptide transport
ND05_RS27230	COG0626	cystathionine gamma-synthase activity
ND05_RS27235	COG0586	Pfam SNARE associated Golgi protein
ND05_RS27240	COG2207	Transcriptional regulator
ND05_RS27245	COG1979	alcohol dehydrogenase
ND05_RS27250	COG0656	L-ascorbic acid biosynthetic process
ND05_RS27265	COG4238	major outer membrane lipoprotein
ND05_RS27270	COG1032	radical SAM domain protein
ND05_RS27275	COG2132	Multicopper oxidase
ND05_RS27280	COG0204	Acyl-transferase
ND05_RS27285	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ND05_RS27295	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
ND05_RS27300	COG3111	PFAM Bacterial OB fold (BOF) protein
ND05_RS27305	COG0745	RESPONSE REGULATOR receiver
ND05_RS27310	COG0642	Histidine kinase
ND05_RS27325	COG2249	NAD(P)H dehydrogenase (quinone) activity
ND05_RS27330	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ND05_RS27335	COG0187	DNA topoisomerase II activity
ND05_RS27340	COG3150	esterase
ND05_RS27345	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ND05_RS27350	COG3151	Protein conserved in bacteria
ND05_RS27355	COG0494	nUDIX hydrolase
ND05_RS27360	COG1538	Outer membrane efflux protein
ND05_RS27375	COG0754	glutathionylspermidine amidase activity
ND05_RS27380	COG3384	dioxygenase
ND05_RS27400	COG2960	long-chain fatty acid transporting porin activity
ND05_RS27405	COG3539	Fimbrial protein
ND05_RS27410	COG3188	usher protein
ND05_RS27420	COG3539	Fimbrial protein
ND05_RS27430	COG1585	Membrane protein implicated in regulation of membrane protease activity
ND05_RS27435	COG2268	Band 7 protein
ND05_RS27470	COG3025	triphosphatase activity
ND05_RS27480	COG4991	sh3 domain protein
ND05_RS27495	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ND05_RS27505	COG0583	DNA-binding transcription factor activity
ND05_RS27515	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ND05_RS27520	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ND05_RS27525	COG0471	metal ion transport
ND05_RS27540	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ND05_RS27545	COG0358	DNA primase activity
ND05_RS27555	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ND05_RS27600	COG2003	Belongs to the UPF0758 family
ND05_RS27695	COG3436	PFAM IS66 Orf2 family protein
ND05_RS27755	COG1358	cellular component organization or biogenesis
ND05_RS27790	COG4372	Transposase
ND05_RS27835	COG0254	rRNA binding
ND05_RS27860	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ND05_RS27865	COG2194	sulfuric ester hydrolase activity
ND05_RS27905	COG0804	urea catabolic process
ND05_RS27960	COG3436	PFAM IS66 Orf2 family protein
ND05_RS27965	COG4372	Transposase
ND05_RS27970	COG3436	PFAM IS66 Orf2 family protein
ND05_RS27975	COG4372	Transposase
ND05_RS27995	COG4983	Phage plasmid primase, P4 family domain protein
ND05_RS28020	COG2375	cellular response to nickel ion
ND05_RS28030	COG1695	Transcriptional regulator
ND05_RS28035	COG0840	transmembrane signaling receptor activity
ND05_RS28050	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ND05_RS28060	COG1609	Transcriptional regulator
ND05_RS28065	COG3250	beta-galactosidase activity
ND05_RS28070	COG2731	YhcH YjgK YiaL family protein
ND05_RS28075	COG0531	amino acid
ND05_RS28085	COG3408	Glycogen debranching enzyme
ND05_RS28085	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
ND05_RS28090	COG1902	pentaerythritol trinitrate reductase activity
ND05_RS28090	COG0446	pyridine nucleotide-disulphide oxidoreductase
ND05_RS28095	COG5499	transcription regulator containing HTH domain
ND05_RS28100	COG4680	protein conserved in bacteria
ND05_RS28115	COG1451	nucleotide metabolic process
ND05_RS28120	COG2949	membrane
ND05_RS28125	COG0673	inositol 2-dehydrogenase activity
ND05_RS28130	COG0861	Integral membrane protein TerC family
ND05_RS28135	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
ND05_RS28145	COG2721	sulfolactate sulfo-lyase activity
ND05_RS28155	COG2271	Major facilitator Superfamily
ND05_RS28185	COG2186	Transcriptional regulator
ND05_RS28190	COG0586	Pfam SNARE associated Golgi protein
ND05_RS28200	COG1422	Protein of unknown function (DUF1090)
ND05_RS28205	COG4575	ribosome binding
ND05_RS28210	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
ND05_RS28220	COG2259	Doxx family
ND05_RS28225	COG0435	Glutathione S-transferase
ND05_RS28230	COG3152	Membrane
ND05_RS28235	COG3152	Membrane
ND05_RS28245	COG0583	DNA-binding transcription factor activity
ND05_RS28250	COG1741	Belongs to the pirin family
ND05_RS28265	COG0814	amino acid
ND05_RS28275	COG1760	l-serine dehydratase
ND05_RS28280	COG0251	oxidation-reduction process
ND05_RS28285	COG1882	Formate acetyltransferase
ND05_RS28290	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ND05_RS28300	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ND05_RS28310	COG0583	DNA-binding transcription factor activity
ND05_RS28335	COG1929	Belongs to the glycerate kinase type-1 family
ND05_RS28340	COG2084	Dehydrogenase
ND05_RS28350	COG2271	Major facilitator Superfamily
ND05_RS28355	COG2721	sulfolactate sulfo-lyase activity
ND05_RS28360	COG2002	toxin-antitoxin pair type II binding
ND05_RS28370	COG1349	DNA-binding transcription factor activity
ND05_RS28385	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ND05_RS28395	COG3716	PTS system mannose fructose sorbose family IID component
ND05_RS28400	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ND05_RS28405	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ND05_RS28410	COG2222	sugar isomerase
ND05_RS28420	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ND05_RS28425	COG3715	PTS system
ND05_RS28430	COG3716	PTS system mannose fructose sorbose family IID component
ND05_RS28435	COG0363	glucosamine-6-phosphate deaminase activity
ND05_RS28440	COG3539	Fimbrial protein
ND05_RS28445	COG3121	Chaperone
ND05_RS28450	COG3188	usher protein
ND05_RS28455	COG3539	Fimbrial protein
ND05_RS28460	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ND05_RS28480	COG2823	Periplasmic or secreted lipoprotein
ND05_RS28485	COG0701	Predicted permease
ND05_RS28490	COG0702	epimerase
ND05_RS28495	COG0693	protein deglycase activity
ND05_RS28510	COG3153	acetyltransferase
ND05_RS28515	COG3154	lipid carrier protein
ND05_RS28520	COG0826	peptidase U32
ND05_RS28525	COG0826	peptidase U32
ND05_RS28530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ND05_RS28535	COG0814	amino acid
ND05_RS28540	COG0513	Belongs to the DEAD box helicase family
ND05_RS28580	COG0195	Participates in both transcription termination and antitermination
ND05_RS28600	COG2194	sulfuric ester hydrolase activity
ND05_RS28610	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ND05_RS28620	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ND05_RS28625	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ND05_RS28635	COG1534	Rna-binding protein
ND05_RS28640	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ND05_RS28645	COG2027	D-alanyl-D-alanine carboxypeptidase
ND05_RS28655	COG0697	spore germination
ND05_RS28670	COG0142	geranyltranstransferase activity
ND05_RS28675	COG3423	Transcriptional regulator
ND05_RS28685	COG5007	Belongs to the BolA IbaG family
ND05_RS28690	COG3113	response to antibiotic
ND05_RS28695	COG2854	intermembrane phospholipid transfer
ND05_RS28700	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ND05_RS28705	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ND05_RS28710	COG1127	ABC transporter
ND05_RS28715	COG0530	calcium, potassium:sodium antiporter activity
ND05_RS28720	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ND05_RS28720	COG0517	IMP dehydrogenase activity
ND05_RS28725	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ND05_RS28730	COG3117	lipopolysaccharide transmembrane transporter activity
ND05_RS28735	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ND05_RS28740	COG1137	ATPase activity
ND05_RS28745	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ND05_RS28750	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ND05_RS28765	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ND05_RS28770	COG0515	serine threonine protein kinase
ND05_RS28780	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
ND05_RS28785	COG0784	Response regulator, receiver
ND05_RS28785	COG2198	Histidine kinase
ND05_RS28785	COG5002	protein histidine kinase activity
ND05_RS28790	COG1242	4 iron, 4 sulfur cluster binding
ND05_RS28805	COG0070	glutamate synthase
ND05_RS28805	COG0069	glutamate synthase activity
ND05_RS28805	COG0067	glutamate synthase
ND05_RS28810	COG0493	'glutamate synthase
ND05_RS28815	COG4804	nuclease activity
ND05_RS28820	COG2731	YhcH YjgK YiaL family protein
ND05_RS28855	COG3069	C4-dicarboxylate transmembrane transporter activity
ND05_RS28860	COG2969	positive regulation of protein catabolic process
ND05_RS28865	COG0625	glutathione transferase activity
ND05_RS28885	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ND05_RS28890	COG3105	Protein conserved in bacteria
ND05_RS28895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ND05_RS28900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ND05_RS28920	COG2732	(Barnase) inhibitor
ND05_RS28940	COG0583	DNA-binding transcription factor activity
ND05_RS28945	COG0312	modulator of DNA gyrase
ND05_RS28950	COG3164	Protein of unknown function
ND05_RS28955	COG1530	ribonuclease E activity
ND05_RS28965	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ND05_RS28970	COG1792	Involved in formation and maintenance of cell shape
ND05_RS28975	COG1077	Cell shape determining protein MreB Mrl
ND05_RS28995	COG0604	alcohol dehydrogenase
ND05_RS29010	COG0511	ligase activity, forming carbon-carbon bonds
ND05_RS29015	COG0439	Biotin carboxylase
ND05_RS29020	COG3924	membrane
ND05_RS29025	COG4145	pantothenate transmembrane transporter activity
ND05_RS29035	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ND05_RS29045	COG2189	Belongs to the N(4) N(6)-methyltransferase family
ND05_RS29055	COG1309	transcriptional regulator
ND05_RS29065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ND05_RS29070	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ND05_RS29085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ND05_RS29090	COG4597	amino acid ABC transporter
ND05_RS29095	COG0765	amino acid transport
ND05_RS29100	COG1126	abc transporter atp-binding protein
ND05_RS29140	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ND05_RS29160	COG0551	DNA topoisomerase type I activity
ND05_RS29170	COG0758	DNA mediated transformation
ND05_RS29190	COG0569	domain protein
ND05_RS29200	COG3036	rescue of stalled ribosome
ND05_RS29205	COG0789	Transcriptional regulator
ND05_RS29245	COG0201	protein transport
ND05_RS29335	COG0089	rRNA binding
ND05_RS29415	COG2964	Protein conserved in bacteria
ND05_RS29420	COG0545	Peptidyl-prolyl cis-trans isomerase
ND05_RS29430	COG1047	Peptidyl-prolyl cis-trans
ND05_RS29435	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
ND05_RS29455	COG0488	(ABC) transporter
ND05_RS29460	COG0429	hydrolase of the alpha beta-hydrolase fold
ND05_RS29470	COG3954	Phosphoribulokinase
ND05_RS29475	COG1765	OsmC-like protein
ND05_RS29485	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ND05_RS29490	COG1289	transmembrane transporter activity
ND05_RS29495	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ND05_RS29500	COG0512	Glutamine amidotransferase of anthranilate synthase
ND05_RS29505	COG2184	nucleotidyltransferase activity
ND05_RS29515	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides