locus-tag	class	description
C6N21_RS00025	COG2890	protein-(glutamine-N5) methyltransferase activity
C6N21_RS00030	COG3094	Invasion gene expression up-regulator, SirB
C6N21_RS00035	COG2912	Transglutaminase-like superfamily
C6N21_RS00060	COG0387	Pfam Sodium calcium exchanger
C6N21_RS00065	COG4572	Cation transport regulator
C6N21_RS00070	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
C6N21_RS00075	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
C6N21_RS00080	COG4932	domain protein
C6N21_RS00085	COG2197	response regulator
C6N21_RS00090	COG3850	Histidine kinase
C6N21_RS00100	COG2223	nitrite transmembrane transporter activity
C6N21_RS00105	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C6N21_RS00110	COG1140	nitrate reductase beta subunit
C6N21_RS00115	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C6N21_RS00120	COG2181	nitrate reductase activity
C6N21_RS00140	COG0788	formyltetrahydrofolate deformylase activity
C6N21_RS00150	COG1752	Esterase of the alpha-beta hydrolase superfamily
C6N21_RS00155	COG0745	RESPONSE REGULATOR receiver
C6N21_RS00160	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C6N21_RS00170	COG1435	thymidine kinase activity
C6N21_RS00175	COG1012	belongs to the aldehyde dehydrogenase family
C6N21_RS00175	COG1454	alcohol dehydrogenase
C6N21_RS00180	COG2095	MarC family integral membrane protein
C6N21_RS00190	COG4166	transmembrane transport
C6N21_RS00195	COG0601	transmembrane transport
C6N21_RS00200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C6N21_RS00205	COG0444	Belongs to the ABC transporter superfamily
C6N21_RS00210	COG4608	Belongs to the ABC transporter superfamily
C6N21_RS00230	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C6N21_RS00235	COG2350	Protein conserved in bacteria
C6N21_RS00240	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
C6N21_RS00245	COG1607	acyl-coa hydrolase
C6N21_RS00265	COG3047	cAMP biosynthetic process
C6N21_RS00280	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6N21_RS00325	COG1396	sequence-specific DNA binding
C6N21_RS00345	COG1846	Transcriptional regulator
C6N21_RS00380	COG1403	HNH endonuclease
C6N21_RS00495	COG3685	Protein conserved in bacteria
C6N21_RS00500	COG3685	Protein conserved in bacteria
C6N21_RS00505	COG3729	General stress protein
C6N21_RS00520	COG0134	indole-3-glycerol-phosphate synthase activity
C6N21_RS00520	COG0135	phosphoribosylanthranilate isomerase activity
C6N21_RS00525	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C6N21_RS00525	COG0512	Glutamine amidotransferase of anthranilate synthase
C6N21_RS00530	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C6N21_RS00540	COG0613	PHP domain protein
C6N21_RS00545	COG0009	L-threonylcarbamoyladenylate synthase
C6N21_RS00550	COG1187	pseudouridine synthase activity
C6N21_RS00555	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
C6N21_RS00560	COG1028	Short-chain dehydrogenase reductase Sdr
C6N21_RS00565	COG0616	signal peptide processing
C6N21_RS00580	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C6N21_RS00590	COG0583	DNA-binding transcription factor activity
C6N21_RS00610	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C6N21_RS00620	COG0671	phosphoesterase, PA-phosphatase related
C6N21_RS00625	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
C6N21_RS00630	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
C6N21_RS00640	COG0023	Translation Initiation Factor
C6N21_RS00650	COG1349	DNA-binding transcription factor activity
C6N21_RS00660	COG5001	Diguanylate cyclase
C6N21_RS00675	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C6N21_RS00675	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C6N21_RS00680	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C6N21_RS00685	COG2852	Protein conserved in bacteria
C6N21_RS00690	COG4172	Belongs to the ABC transporter superfamily
C6N21_RS00695	COG4172	Belongs to the ABC transporter superfamily
C6N21_RS00700	COG4171	peptide transport system, permease
C6N21_RS00705	COG4168	peptide transport system, permease
C6N21_RS00710	COG4166	transmembrane transport
C6N21_RS00725	COG0531	amino acid
C6N21_RS00730	COG0174	glutamine synthetase
C6N21_RS00735	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C6N21_RS00740	COG1396	sequence-specific DNA binding
C6N21_RS00740	COG1917	Cupin 2, conserved barrel domain protein
C6N21_RS00750	COG1012	belongs to the aldehyde dehydrogenase family
C6N21_RS00755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C6N21_RS00760	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C6N21_RS00765	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C6N21_RS00770	COG1842	Phage shock protein A
C6N21_RS00780	COG1983	PspC domain protein
C6N21_RS00790	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C6N21_RS00795	COG0366	Alpha amylase catalytic
C6N21_RS00805	COG1175	transmembrane transport
C6N21_RS00810	COG0395	ABC-type sugar transport system, permease component
C6N21_RS00815	COG1063	alcohol dehydrogenase
C6N21_RS00820	COG1082	Xylose isomerase domain protein TIM barrel
C6N21_RS00825	COG0673	inositol 2-dehydrogenase activity
C6N21_RS00830	COG1554	hydrolase, family 65, central catalytic
C6N21_RS00835	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C6N21_RS00840	COG3842	ATPase activity
C6N21_RS00850	COG1609	Transcriptional regulator
C6N21_RS00855	COG3106	COG3106 Predicted ATPase
C6N21_RS00865	COG3283	Transcriptional regulator of aromatic amino acids metabolism
C6N21_RS00870	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
C6N21_RS00875	COG4948	Mandelate Racemase Muconate Lactonizing
C6N21_RS00880	COG2866	Carboxypeptidase
C6N21_RS00885	COG0702	epimerase
C6N21_RS00890	COG1073	alpha beta
C6N21_RS00895	COG1073	alpha beta
C6N21_RS00900	COG0583	DNA-binding transcription factor activity
C6N21_RS00905	COG4166	transmembrane transport
C6N21_RS00910	COG0668	transmembrane transport
C6N21_RS00915	COG3182	Iron-regulated membrane protein
C6N21_RS00920	COG0589	response to stress
C6N21_RS00925	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C6N21_RS00930	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C6N21_RS00935	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
C6N21_RS00945	COG1473	amidohydrolase
C6N21_RS00950	COG1473	amidohydrolase
C6N21_RS00955	COG0583	DNA-binding transcription factor activity
C6N21_RS00965	COG2840	Smr protein MutS2
C6N21_RS00970	COG3706	GGDEF domain
C6N21_RS00985	COG0513	Belongs to the DEAD box helicase family
C6N21_RS00995	COG0582	viral genome integration into host DNA
C6N21_RS01015	COG3723	Recombinational DNA repair protein, rece pathway
C6N21_RS01020	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6N21_RS01065	COG1484	DNA-dependent DNA replication
C6N21_RS01070	COG1846	Transcriptional regulator
C6N21_RS01170	COG3772	lysozyme
C6N21_RS01200	COG0582	viral genome integration into host DNA
C6N21_RS01270	COG0740	serine-type endopeptidase activity
C6N21_RS01385	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6N21_RS01390	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C6N21_RS01405	COG0582	viral genome integration into host DNA
C6N21_RS01415	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C6N21_RS01425	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6N21_RS01490	COG1846	Transcriptional regulator
C6N21_RS01525	COG3111	PFAM Bacterial OB fold (BOF) protein
C6N21_RS01535	COG1403	HNH endonuclease
C6N21_RS01540	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C6N21_RS01555	COG2207	Transcriptional regulator
C6N21_RS01605	COG3772	lysozyme
C6N21_RS01640	COG4220	transposase activity
C6N21_RS01660	COG1030	water channel activity
C6N21_RS01745	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6N21_RS01770	COG0589	response to stress
C6N21_RS01775	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C6N21_RS01780	COG0674	pyruvate-flavodoxin oxidoreductase activity
C6N21_RS01780	COG1013	pyruvate-flavodoxin oxidoreductase activity
C6N21_RS01780	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
C6N21_RS01780	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C6N21_RS01785	COG3042	response to heat
C6N21_RS01790	COG3187	Heat shock protein
C6N21_RS01795	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C6N21_RS01800	COG2911	Protein conserved in bacteria
C6N21_RS01810	COG3784	Protein of unknown function (DUF1318)
C6N21_RS01815	COG2207	Transcriptional regulator
C6N21_RS01820	COG1012	belongs to the aldehyde dehydrogenase family
C6N21_RS01825	COG3733	amine oxidase
C6N21_RS01830	COG1012	belongs to the aldehyde dehydrogenase family
C6N21_RS01830	COG2030	dehydratase
C6N21_RS01835	COG3396	Phenylacetate-CoA oxygenase
C6N21_RS01840	COG3460	Phenylacetate-CoA oxygenase
C6N21_RS01845	COG3396	Phenylacetate-CoA oxygenase
C6N21_RS01850	COG2151	metal-sulfur cluster biosynthetic enzyme
C6N21_RS01855	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C6N21_RS01860	COG1024	Enoyl-CoA hydratase
C6N21_RS01865	COG1024	Enoyl-CoA hydratase
C6N21_RS01870	COG1250	3-hydroxyacyl-CoA dehydrogenase
C6N21_RS01875	COG2050	protein possibly involved in aromatic compounds catabolism
C6N21_RS01880	COG0183	Belongs to the thiolase family
C6N21_RS01885	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
C6N21_RS01890	COG3327	negative regulation of DNA-templated transcription, initiation
C6N21_RS01895	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C6N21_RS01900	COG0667	Aldo Keto reductase
C6N21_RS01915	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C6N21_RS01920	COG4589	Belongs to the CDS family
C6N21_RS01930	COG2453	phosphatase
C6N21_RS01930	COG0671	phosphoesterase, PA-phosphatase related
C6N21_RS01940	COG1643	Atp-dependent helicase
C6N21_RS01945	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C6N21_RS01950	COG1012	belongs to the aldehyde dehydrogenase family
C6N21_RS01955	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C6N21_RS01960	COG3038	cytochrome b561
C6N21_RS01975	COG0840	transmembrane signaling receptor activity
C6N21_RS01980	COG0583	DNA-binding transcription factor activity
C6N21_RS01985	COG5383	Protein conserved in bacteria
C6N21_RS02005	COG2841	Protein conserved in bacteria
C6N21_RS02010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C6N21_RS02015	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C6N21_RS02020	COG1275	C4-dicarboxylate transporter malic acid transport protein
C6N21_RS02025	COG0500	methyltransferase
C6N21_RS02045	COG0675	Transposase, IS605 OrfB family
C6N21_RS02050	COG3135	benzoate transporter
C6N21_RS02055	COG1396	sequence-specific DNA binding
C6N21_RS02060	COG0826	peptidase U32
C6N21_RS02070	COG1724	mRNA binding
C6N21_RS02075	COG1598	PFAM Uncharacterised protein family UPF0150
C6N21_RS02080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C6N21_RS02085	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C6N21_RS02090	COG3842	ATPase activity
C6N21_RS02095	COG1176	ABC-type spermidine putrescine transport system, permease component I
C6N21_RS02100	COG1177	transmembrane transport
C6N21_RS02135	COG3238	Protein conserved in bacteria
C6N21_RS02140	COG1247	-acetyltransferase
C6N21_RS02150	COG2130	NADP-dependent
C6N21_RS02155	COG1802	Transcriptional regulator
C6N21_RS02160	COG4772	TonB-dependent receptor
C6N21_RS02170	COG3391	amine dehydrogenase activity
C6N21_RS02180	COG0625	glutathione transferase activity
C6N21_RS02205	COG5433	transposase activity
C6N21_RS02210	COG5433	transposase activity
C6N21_RS02220	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C6N21_RS02225	COG2162	N-hydroxyarylamine O-acetyltransferase activity
C6N21_RS02230	COG0384	phenazine biosynthesis protein PhzF
C6N21_RS02235	COG2181	nitrate reductase activity
C6N21_RS02240	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C6N21_RS02245	COG1140	nitrate reductase beta subunit
C6N21_RS02250	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C6N21_RS02255	COG2223	nitrite transmembrane transporter activity
C6N21_RS02265	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C6N21_RS02270	COG0697	spore germination
C6N21_RS02275	COG3383	formate dehydrogenase (NAD+) activity
C6N21_RS02275	COG0243	molybdopterin cofactor binding
C6N21_RS02280	COG0243	molybdopterin cofactor binding
C6N21_RS02280	COG3383	formate dehydrogenase (NAD+) activity
C6N21_RS02285	COG0437	4 iron, 4 sulfur cluster binding
C6N21_RS02290	COG2864	formate dehydrogenase
C6N21_RS02295	COG3093	addiction module antidote protein HigA
C6N21_RS02300	COG1064	alcohol dehydrogenase
C6N21_RS02325	COG1764	response to oxidative stress
C6N21_RS02330	COG4608	Belongs to the ABC transporter superfamily
C6N21_RS02335	COG0444	Belongs to the ABC transporter superfamily
C6N21_RS02340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C6N21_RS02345	COG0601	transmembrane transport
C6N21_RS02350	COG0747	negative chemotaxis
C6N21_RS02355	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
C6N21_RS02360	COG2199	diguanylate cyclase activity
C6N21_RS02360	COG2200	EAL domain
C6N21_RS02360	COG2202	Pas domain
C6N21_RS02370	COG1649	PFAM Uncharacterised BCR, COG1649
C6N21_RS02375	COG0531	amino acid
C6N21_RS02380	COG0076	glutamate decarboxylase activity
C6N21_RS02385	COG0612	Peptidase, M16
C6N21_RS02390	COG4771	TonB-dependent receptor
C6N21_RS02395	COG4178	(ABC) transporter
C6N21_RS02400	COG0641	radical SAM
C6N21_RS02410	COG2207	Transcriptional regulator
C6N21_RS02420	COG0243	molybdopterin cofactor binding
C6N21_RS02425	COG3539	Fimbrial protein
C6N21_RS02430	COG3539	Fimbrial protein
C6N21_RS02435	COG3539	Fimbrial protein
C6N21_RS02440	COG3188	usher protein
C6N21_RS02445	COG3121	Chaperone
C6N21_RS02450	COG3539	Fimbrial protein
C6N21_RS02465	COG3550	peptidyl-serine autophosphorylation
C6N21_RS02470	COG1396	sequence-specific DNA binding
C6N21_RS02530	COG3781	membrane
C6N21_RS02550	COG2199	diguanylate cyclase activity
C6N21_RS02565	COG2066	Belongs to the glutaminase family
C6N21_RS02570	COG1012	belongs to the aldehyde dehydrogenase family
C6N21_RS02575	COG0583	DNA-binding transcription factor activity
C6N21_RS02595	COG1846	Transcriptional regulator
C6N21_RS02600	COG4977	sequence-specific DNA binding
C6N21_RS02630	COG1447	Phosphotransferase system cellobiose-specific component IIA
C6N21_RS02635	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C6N21_RS02645	COG2188	Transcriptional regulator
C6N21_RS02650	COG0697	spore germination
C6N21_RS02655	COG2814	Major facilitator Superfamily
C6N21_RS02665	COG3706	GGDEF domain
C6N21_RS02670	COG3111	PFAM Bacterial OB fold (BOF) protein
C6N21_RS02675	COG1546	Belongs to the CinA family
C6N21_RS02680	COG0339	signal peptide processing
C6N21_RS02690	COG4221	oxidoreductase activity
C6N21_RS02695	COG1802	Transcriptional regulator
C6N21_RS02710	COG0477	Major facilitator Superfamily
C6N21_RS02740	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6N21_RS02820	COG0740	serine-type endopeptidase activity
C6N21_RS02855	COG5562	phage envelope protein
C6N21_RS02875	COG1278	Cold shock
C6N21_RS02885	COG3772	lysozyme
C6N21_RS02900	COG1278	Cold shock
C6N21_RS02905	COG1278	Cold shock
C6N21_RS02915	COG0484	heat shock protein binding
C6N21_RS02920	COG1403	HNH endonuclease
C6N21_RS02950	COG4372	Transposase
C6N21_RS02955	COG3436	PFAM IS66 Orf2 family protein
C6N21_RS02960	COG4372	Transposase
C6N21_RS02965	COG3436	PFAM IS66 Orf2 family protein
C6N21_RS02975	COG1063	alcohol dehydrogenase
C6N21_RS02980	COG4948	Mandelate Racemase Muconate Lactonizing
C6N21_RS03000	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C6N21_RS03015	COG0243	molybdopterin cofactor binding
C6N21_RS03020	COG0243	molybdopterin cofactor binding
C6N21_RS03025	COG0437	4 iron, 4 sulfur cluster binding
C6N21_RS03030	COG3302	dmso reductase anchor subunit
C6N21_RS03035	COG3381	protein complex oligomerization
C6N21_RS03045	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C6N21_RS03050	COG1940	carbohydrate kinase activity
C6N21_RS03055	COG0583	DNA-binding transcription factor activity
C6N21_RS03060	COG2814	Major facilitator Superfamily
C6N21_RS03080	COG3591	Belongs to the peptidase S1B family
C6N21_RS03105	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
C6N21_RS03110	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
C6N21_RS03125	COG0531	amino acid
C6N21_RS03135	COG3136	membrane protein required for alginate biosynthesis
C6N21_RS03140	COG0745	RESPONSE REGULATOR receiver
C6N21_RS03145	COG2205	protein histidine kinase activity
C6N21_RS03155	COG0114	fumarate hydratase activity
C6N21_RS03160	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C6N21_RS03160	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C6N21_RS03165	COG1482	cell wall glycoprotein biosynthetic process
C6N21_RS03170	COG5339	Protein conserved in bacteria
C6N21_RS03185	COG3250	beta-galactosidase activity
C6N21_RS03190	COG1309	transcriptional regulator
C6N21_RS03195	COG1028	Short-chain dehydrogenase reductase Sdr
C6N21_RS03200	COG1609	Transcriptional regulator
C6N21_RS03205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6N21_RS03205	COG1263	PTS System
C6N21_RS03210	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C6N21_RS03220	COG0673	inositol 2-dehydrogenase activity
C6N21_RS03265	COG4659	FMN binding
C6N21_RS03275	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C6N21_RS03285	COG3104	oligopeptide transport
C6N21_RS03290	COG0625	glutathione transferase activity
C6N21_RS03295	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
C6N21_RS03310	COG3895	Periplasmic Protein
C6N21_RS03320	COG3133	Outer membrane lipoprotein
C6N21_RS03335	COG1566	PFAM secretion protein HlyD family protein
C6N21_RS03345	COG2032	superoxide dismutase activity
C6N21_RS03350	COG4989	oxidoreductase activity
C6N21_RS03355	COG3313	Fe-S protein
C6N21_RS03360	COG1309	transcriptional regulator
C6N21_RS03365	COG1902	pentaerythritol trinitrate reductase activity
C6N21_RS03370	COG0346	lactoylglutathione lyase activity
C6N21_RS03380	COG1201	RNA secondary structure unwinding
C6N21_RS03385	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C6N21_RS03390	COG0791	NLP P60 protein
C6N21_RS03395	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C6N21_RS03400	COG2814	Major facilitator Superfamily
C6N21_RS03420	COG0583	DNA-binding transcription factor activity
C6N21_RS03425	COG2814	Major facilitator Superfamily
C6N21_RS03430	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C6N21_RS03435	COG0307	riboflavin synthase, alpha
C6N21_RS03445	COG3468	outer membrane autotransporter barrel domain protein
C6N21_RS03465	COG4529	Protein conserved in bacteria
C6N21_RS03475	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
C6N21_RS03480	COG0437	4 iron, 4 sulfur cluster binding
C6N21_RS03490	COG2414	aldehyde ferredoxin oxidoreductase
C6N21_RS03495	COG0437	4 iron, 4 sulfur cluster binding
C6N21_RS03505	COG0469	pyruvate kinase activity
C6N21_RS03510	COG4238	major outer membrane lipoprotein
C6N21_RS03515	COG1376	ErfK ybiS ycfS ynhG family protein
C6N21_RS03535	COG0396	ATPase activity
C6N21_RS03540	COG0719	Fe-S assembly protein
C6N21_RS03545	COG0316	Belongs to the HesB IscA family
C6N21_RS03555	COG2050	protein possibly involved in aromatic compounds catabolism
C6N21_RS03570	COG0628	permease
C6N21_RS03585	COG0738	Major facilitator superfamily
C6N21_RS03605	COG4670	ketone body catabolic process
C6N21_RS03610	COG1960	acyl-CoA dehydrogenase activity
C6N21_RS03615	COG1917	Cupin 2, conserved barrel domain protein
C6N21_RS03615	COG2207	Transcriptional regulator
C6N21_RS03625	COG2086	electron transfer activity
C6N21_RS03630	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C6N21_RS03635	COG0644	oxidoreductase
C6N21_RS03640	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C6N21_RS03645	COG0318	PFAM AMP-dependent synthetase and ligase
C6N21_RS03650	COG0574	Belongs to the PEP-utilizing enzyme family
C6N21_RS03650	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C6N21_RS03665	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C6N21_RS03670	COG4256	Hemin uptake protein
C6N21_RS03680	COG2200	EAL domain
C6N21_RS03685	COG0791	NLP P60 protein
C6N21_RS03695	COG0386	Belongs to the glutathione peroxidase family
C6N21_RS03755	COG3137	Salt-induced outer membrane protein
C6N21_RS03760	COG1105	Belongs to the carbohydrate kinase PfkB family
C6N21_RS03770	COG3001	Fructosamine kinase
C6N21_RS03780	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C6N21_RS03785	COG1988	membrane-bound metal-dependent
C6N21_RS03790	COG1823	symporter activity
C6N21_RS03805	COG0753	catalase activity
C6N21_RS03815	COG1486	melibiose metabolic process
C6N21_RS03820	COG1917	Cupin 2, conserved barrel domain protein
C6N21_RS03820	COG2169	Transcriptional regulator
C6N21_RS03825	COG1447	Phosphotransferase system cellobiose-specific component IIA
C6N21_RS03830	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C6N21_RS03835	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C6N21_RS03845	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C6N21_RS03855	COG0322	excinuclease ABC activity
C6N21_RS03865	COG3678	ATP-independent chaperone mediated protein folding
C6N21_RS03900	COG0708	Exodeoxyribonuclease III
C6N21_RS03905	COG0398	Pfam SNARE associated Golgi protein
C6N21_RS03915	COG0398	Pfam SNARE associated Golgi protein
C6N21_RS03920	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C6N21_RS03925	COG4134	Bacterial extracellular solute-binding protein
C6N21_RS03930	COG4135	transport system, permease component
C6N21_RS03935	COG4136	ATPase activity
C6N21_RS03940	COG2897	thiosulfate sulfurtransferase activity
C6N21_RS03945	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C6N21_RS03950	COG0494	nUDIX hydrolase
C6N21_RS03960	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C6N21_RS03970	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C6N21_RS03985	COG0778	Nitroreductase
C6N21_RS03995	COG0616	signal peptide processing
C6N21_RS04000	COG0252	asparaginase activity
C6N21_RS04005	COG1335	isochorismatase
C6N21_RS04010	COG2814	Major facilitator Superfamily
C6N21_RS04015	COG1349	DNA-binding transcription factor activity
C6N21_RS04020	COG0667	Aldo Keto reductase
C6N21_RS04025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6N21_RS04030	COG0191	fructose-bisphosphate aldolase activity
C6N21_RS04035	COG1063	alcohol dehydrogenase
C6N21_RS04040	COG2271	Major facilitator Superfamily
C6N21_RS04045	COG1063	alcohol dehydrogenase
C6N21_RS04050	COG3139	Protein of unknown function (DUF1315)
C6N21_RS04060	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C6N21_RS04065	COG0676	glucose-6-phosphate 1-epimerase activity
C6N21_RS04070	COG0656	L-ascorbic acid biosynthetic process
C6N21_RS04075	COG3713	MltA-interacting MipA family protein
C6N21_RS04080	COG2766	serine protein kinase
C6N21_RS04090	COG2199	diguanylate cyclase activity
C6N21_RS04095	COG2199	diguanylate cyclase activity
C6N21_RS04100	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C6N21_RS04115	COG2207	Transcriptional regulator
C6N21_RS04120	COG2807	transmembrane transport
C6N21_RS04130	COG3042	response to heat
C6N21_RS04135	COG2203	Gaf domain
C6N21_RS04135	COG2199	diguanylate cyclase activity
C6N21_RS04150	COG2261	transglycosylase associated protein
C6N21_RS04160	COG3615	Tellurite resistance protein tehB
C6N21_RS04170	COG0583	DNA-binding transcription factor activity
C6N21_RS04175	COG0473	3-isopropylmalate dehydrogenase activity
C6N21_RS04180	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C6N21_RS04185	COG4638	Rieske (2fe-2S)
C6N21_RS04190	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C6N21_RS04195	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
C6N21_RS04200	COG0318	PFAM AMP-dependent synthetase and ligase
C6N21_RS04205	COG3065	identical protein binding
C6N21_RS04210	COG1214	PFAM Peptidase M22, glycoprotease
C6N21_RS04220	COG0251	oxidation-reduction process
C6N21_RS04235	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C6N21_RS04245	COG1760	l-serine dehydratase
C6N21_RS04255	COG1253	flavin adenine dinucleotide binding
C6N21_RS04270	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6N21_RS04270	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6N21_RS04275	COG3715	PTS system
C6N21_RS04280	COG3716	PTS system mannose fructose sorbose family IID component
C6N21_RS04300	COG2226	methyltransferase
C6N21_RS04335	COG1414	Transcriptional regulator
C6N21_RS04340	COG2814	Major facilitator Superfamily
C6N21_RS04350	COG0793	Belongs to the peptidase S41A family
C6N21_RS04360	COG1956	GAF domain-containing protein
C6N21_RS04365	COG2995	paraquat-inducible protein a
C6N21_RS04370	COG3008	intermembrane lipid transfer
C6N21_RS04390	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C6N21_RS04400	COG1276	copper resistance
C6N21_RS04405	COG2372	response to copper ion
C6N21_RS04415	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C6N21_RS04420	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6N21_RS04425	COG1770	oligopeptidase
C6N21_RS04430	COG2979	Protein of unknown function (DUF533)
C6N21_RS04440	COG3141	response to X-ray
C6N21_RS04450	COG0800	Aldolase
C6N21_RS04455	COG0129	dihydroxy-acid dehydratase activity
C6N21_RS04460	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C6N21_RS04465	COG1737	Transcriptional regulator
C6N21_RS04470	COG0469	pyruvate kinase activity
C6N21_RS04475	COG1560	Kdo2-lipid A biosynthetic process
C6N21_RS04480	COG0739	heme binding
C6N21_RS04485	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
C6N21_RS04495	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C6N21_RS04525	COG0217	transcriptional regulatory protein
C6N21_RS04530	COG0494	nUDIX hydrolase
C6N21_RS04540	COG1335	isochorismatase
C6N21_RS04545	COG1801	Protein of unknown function DUF72
C6N21_RS04550	COG3788	relative of glutathione S-transferase, MAPEG superfamily
C6N21_RS04565	COG0243	molybdopterin cofactor binding
C6N21_RS04570	COG3005	denitrification pathway
C6N21_RS04580	COG3102	Protein conserved in bacteria
C6N21_RS04600	COG3436	PFAM IS66 Orf2 family protein
C6N21_RS04605	COG4372	Transposase
C6N21_RS04615	COG3436	PFAM IS66 Orf2 family protein
C6N21_RS04620	COG4372	Transposase
C6N21_RS04625	COG3755	Protein conserved in bacteria
C6N21_RS04635	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C6N21_RS04640	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C6N21_RS04645	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
C6N21_RS04650	COG0745	RESPONSE REGULATOR receiver
C6N21_RS04655	COG2201	protein-glutamate methylesterase activity
C6N21_RS04660	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C6N21_RS04665	COG0840	transmembrane signaling receptor activity
C6N21_RS04670	COG0840	transmembrane signaling receptor activity
C6N21_RS04675	COG0835	chemotaxis
C6N21_RS04680	COG2198	Histidine kinase
C6N21_RS04680	COG0643	Histidine kinase
C6N21_RS04685	COG1360	Flagellar Motor Protein
C6N21_RS04690	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C6N21_RS04705	COG0589	response to stress
C6N21_RS04715	COG1877	trehalose-phosphatase activity
C6N21_RS04720	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6N21_RS04725	COG1129	ABC transporter
C6N21_RS04730	COG1879	ABC-type sugar transport system periplasmic component
C6N21_RS04740	COG1528	Iron-storage protein
C6N21_RS04760	COG1528	Iron-storage protein
C6N21_RS04770	COG0814	amino acid
C6N21_RS04775	COG3012	SEC-C Motif Domain Protein
C6N21_RS04775	COG3318	Belongs to the UPF0149 family
C6N21_RS04780	COG4974	Belongs to the 'phage' integrase family
C6N21_RS04890	COG4695	Portal protein
C6N21_RS04975	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6N21_RS04975	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6N21_RS04980	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C6N21_RS05070	COG2197	response regulator
C6N21_RS05085	COG2197	response regulator
C6N21_RS05090	COG1126	abc transporter atp-binding protein
C6N21_RS05095	COG0765	amino acid transport
C6N21_RS05105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6N21_RS05115	COG1191	sigma factor activity
C6N21_RS05130	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C6N21_RS05135	COG1516	flagellar protein fliS
C6N21_RS05145	COG0366	Alpha amylase catalytic
C6N21_RS05160	COG2391	methyltransferase activity
C6N21_RS05165	COG0425	Belongs to the sulfur carrier protein TusA family
C6N21_RS05170	COG2135	peptidase activity
C6N21_RS05190	COG1766	The M ring may be actively involved in energy transduction
C6N21_RS05195	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C6N21_RS05200	COG1317	bacterial-type flagellum organization
C6N21_RS05205	COG1157	protein secretion by the type III secretion system
C6N21_RS05210	COG2882	bacterial-type flagellum organization
C6N21_RS05215	COG3144	bacterial-type flagellum assembly
C6N21_RS05220	COG1580	Controls the rotational direction of flagella during chemotaxis
C6N21_RS05225	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C6N21_RS05230	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C6N21_RS05235	COG3190	flagellar
C6N21_RS05240	COG1338	Plays a role in the flagellum-specific transport system
C6N21_RS05245	COG1987	bacterial-type flagellum assembly
C6N21_RS05250	COG1684	flagellar biosynthetic protein fliR
C6N21_RS05255	COG2197	response regulator
C6N21_RS05290	COG5475	Uncharacterized small protein (DUF2158)
C6N21_RS05295	COG2354	Protein conserved in bacteria
C6N21_RS05300	COG0697	spore germination
C6N21_RS05305	COG3727	T/G mismatch-specific endonuclease activity
C6N21_RS05310	COG0270	DNA (cytosine-5-)-methyltransferase activity
C6N21_RS05315	COG1418	mRNA catabolic process
C6N21_RS05325	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C6N21_RS05340	COG2205	protein histidine kinase activity
C6N21_RS05345	COG0745	RESPONSE REGULATOR receiver
C6N21_RS05350	COG2351	hydroxyisourate hydrolase activity
C6N21_RS05365	COG3443	Belongs to the bacterial solute-binding protein 9 family
C6N21_RS05370	COG3038	cytochrome b561
C6N21_RS05455	COG1470	cell adhesion involved in biofilm formation
C6N21_RS05455	COG1388	LysM domain
C6N21_RS05475	COG0477	Major facilitator Superfamily
C6N21_RS05480	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C6N21_RS05485	COG0217	transcriptional regulatory protein
C6N21_RS05505	COG0534	Mate efflux family protein
C6N21_RS05515	COG0582	viral genome integration into host DNA
C6N21_RS05545	COG3209	COG3209 Rhs family protein
C6N21_RS05555	COG0583	DNA-binding transcription factor activity
C6N21_RS05560	COG0583	DNA-binding transcription factor activity
C6N21_RS05570	COG1376	ErfK ybiS ycfS ynhG family protein
C6N21_RS05585	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
C6N21_RS05645	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
C6N21_RS05660	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
C6N21_RS05675	COG1012	belongs to the aldehyde dehydrogenase family
C6N21_RS05675	COG1454	alcohol dehydrogenase
C6N21_RS05680	COG4656	Part of a membrane complex involved in electron transport
C6N21_RS05705	COG1289	transmembrane transporter activity
C6N21_RS05715	COG1686	Belongs to the peptidase S11 family
C6N21_RS05720	COG2925	Exonuclease
C6N21_RS05725	COG0425	Belongs to the sulfur carrier protein TusA family
C6N21_RS05730	COG2391	methyltransferase activity
C6N21_RS05735	COG0531	amino acid
C6N21_RS05745	COG0583	DNA-binding transcription factor activity
C6N21_RS05750	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C6N21_RS05755	COG4115	mRNA cleavage
C6N21_RS05760	COG2161	toxin-antitoxin pair type II binding
C6N21_RS05780	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C6N21_RS05790	COG0131	Imidazoleglycerol-phosphate dehydratase
C6N21_RS05790	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C6N21_RS05795	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C6N21_RS05815	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
C6N21_RS05820	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C6N21_RS05825	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C6N21_RS05830	COG0438	transferase activity, transferring glycosyl groups
C6N21_RS05835	COG0438	transferase activity, transferring glycosyl groups
C6N21_RS05840	COG0367	asparagine synthase
C6N21_RS05855	COG1215	transferase activity, transferring glycosyl groups
C6N21_RS05880	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C6N21_RS05895	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
C6N21_RS05900	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C6N21_RS05910	COG0438	transferase activity, transferring glycosyl groups
C6N21_RS05915	COG2327	Polysaccharide pyruvyl transferase
C6N21_RS05920	COG2244	polysaccharide biosynthetic process
C6N21_RS05925	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C6N21_RS05930	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C6N21_RS05935	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
C6N21_RS05935	COG0662	Cupin 2, conserved barrel domain protein
C6N21_RS05940	COG0297	glycogen (starch) synthase activity
C6N21_RS05945	COG1051	belongs to the nudix hydrolase family
C6N21_RS05950	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C6N21_RS05955	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
C6N21_RS05960	COG0110	maltose O-acetyltransferase activity
C6N21_RS05965	COG1216	Glycosyl transferase, family 2
C6N21_RS05975	COG0438	transferase activity, transferring glycosyl groups
C6N21_RS05980	COG1045	serine acetyltransferase
C6N21_RS05985	COG0463	Glycosyl transferase, family 2
C6N21_RS05990	COG3206	protein involved in exopolysaccharide biosynthesis
C6N21_RS05990	COG0489	protein tyrosine kinase activity
C6N21_RS05995	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C6N21_RS06000	COG1596	polysaccharide export
C6N21_RS06005	COG1253	flavin adenine dinucleotide binding
C6N21_RS06010	COG2982	Protein involved in outer membrane biogenesis
C6N21_RS06020	COG0572	uridine kinase
C6N21_RS06025	COG5002	protein histidine kinase activity
C6N21_RS06025	COG5001	Diguanylate cyclase
C6N21_RS06025	COG3447	MASE1 domain protein
C6N21_RS06030	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C6N21_RS06035	COG0443	Heat shock 70 kDa protein
C6N21_RS06040	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
C6N21_RS06045	COG3779	Protein conserved in bacteria
C6N21_RS06050	COG0631	protein serine/threonine phosphatase activity
C6N21_RS06055	COG4245	von Willebrand factor, type A
C6N21_RS06100	COG2205	protein histidine kinase activity
C6N21_RS06105	COG0745	RESPONSE REGULATOR receiver
C6N21_RS06115	COG3609	addiction module antidote protein, CC2985 family
C6N21_RS06125	COG0826	peptidase U32
C6N21_RS06150	COG1063	alcohol dehydrogenase
C6N21_RS06155	COG3775	system Galactitol-specific IIC component
C6N21_RS06160	COG3414	Phosphotransferase system galactitol-specific IIB component
C6N21_RS06165	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6N21_RS06180	COG1830	Aldolase
C6N21_RS06185	COG2211	Major facilitator Superfamily
C6N21_RS06190	COG1397	ADP-ribosylglycohydrolase
C6N21_RS06195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6N21_RS06200	COG2188	Transcriptional regulator
C6N21_RS06205	COG3757	hydrolase, family 25
C6N21_RS06210	COG0351	phosphomethylpyrimidine kinase
C6N21_RS06225	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
C6N21_RS06230	COG5455	response to cobalt ion
C6N21_RS06235	COG3539	Fimbrial protein
C6N21_RS06240	COG3188	usher protein
C6N21_RS06245	COG3121	Chaperone
C6N21_RS06250	COG3539	Fimbrial protein
C6N21_RS06265	COG0489	protein tyrosine kinase activity
C6N21_RS06275	COG3831	ATPase activity
C6N21_RS06285	COG3831	ATPase activity
C6N21_RS06300	COG0714	Associated with various cellular activities
C6N21_RS06305	COG2425	protein containing a von Willebrand factor type A (vWA) domain
C6N21_RS06310	COG3552	Protein containing von Willebrand factor type A (VWA) domain
C6N21_RS06315	COG4715	Zinc finger, swim domain protein
C6N21_RS06320	COG4808	Protein conserved in bacteria
C6N21_RS06325	COG4807	Protein conserved in bacteria
C6N21_RS06330	COG3279	Response regulator of the LytR AlgR family
C6N21_RS06335	COG3275	phosphorelay sensor kinase activity
C6N21_RS06340	COG0789	Transcriptional regulator
C6N21_RS06350	COG1174	glycine betaine transport
C6N21_RS06355	COG1125	glycine betaine transport
C6N21_RS06360	COG1174	glycine betaine transport
C6N21_RS06365	COG1732	Glycine betaine
C6N21_RS06370	COG1472	Belongs to the glycosyl hydrolase 3 family
C6N21_RS06375	COG0277	FAD linked oxidase domain protein
C6N21_RS06380	COG1686	Belongs to the peptidase S11 family
C6N21_RS06390	COG0586	Pfam SNARE associated Golgi protein
C6N21_RS06395	COG1028	Short-chain dehydrogenase reductase Sdr
C6N21_RS06420	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C6N21_RS06430	COG1346	cytolysis
C6N21_RS06440	COG2949	membrane
C6N21_RS06450	COG0493	'glutamate synthase
C6N21_RS06455	COG0167	dihydroorotate dehydrogenase activity
C6N21_RS06455	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
C6N21_RS06460	COG4211	Belongs to the binding-protein-dependent transport system permease family
C6N21_RS06465	COG1129	ABC transporter
C6N21_RS06470	COG1879	ABC-type sugar transport system periplasmic component
C6N21_RS06475	COG1609	Transcriptional regulator
C6N21_RS06485	COG2311	Membrane
C6N21_RS06510	COG4771	TonB-dependent receptor
C6N21_RS06520	COG0833	amino acid
C6N21_RS06530	COG0583	DNA-binding transcription factor activity
C6N21_RS06535	COG2855	membrane
C6N21_RS06545	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6N21_RS06545	COG1522	sequence-specific DNA binding
C6N21_RS06550	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C6N21_RS06560	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C6N21_RS06565	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C6N21_RS06570	COG2313	pseudouridylate synthase activity
C6N21_RS06575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6N21_RS06580	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
C6N21_RS06580	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6N21_RS06580	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6N21_RS06585	COG1105	Belongs to the carbohydrate kinase PfkB family
C6N21_RS06590	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6N21_RS06590	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6N21_RS06595	COG2814	Major facilitator Superfamily
C6N21_RS06610	COG0246	Mannitol dehydrogenase
C6N21_RS06615	COG0523	cobalamin synthesis protein
C6N21_RS06620	COG0671	phosphoesterase, PA-phosphatase related
C6N21_RS06625	COG0791	NLP P60 protein
C6N21_RS06630	COG2200	EAL domain
C6N21_RS06635	COG4166	transmembrane transport
C6N21_RS06640	COG4174	ABC transporter (Permease)
C6N21_RS06645	COG4239	(ABC) transporter, permease
C6N21_RS06650	COG4172	Belongs to the ABC transporter superfamily
C6N21_RS06665	COG2814	Major facilitator Superfamily
C6N21_RS06670	COG1187	pseudouridine synthase activity
C6N21_RS06680	COG1061	Type III restriction enzyme res subunit
C6N21_RS06700	COG3083	sulfuric ester hydrolase activity
C6N21_RS06715	COG3468	outer membrane autotransporter barrel domain protein
C6N21_RS06725	COG2197	response regulator
C6N21_RS06730	COG3088	subunit of a heme lyase
C6N21_RS06730	COG4235	cytochrome complex assembly
C6N21_RS06735	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C6N21_RS06740	COG1138	Cytochrome C-type biogenesis protein
C6N21_RS06750	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C6N21_RS06755	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C6N21_RS06760	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C6N21_RS06770	COG3005	denitrification pathway
C6N21_RS06775	COG3043	anaerobic respiration
C6N21_RS06780	COG0348	domain, Protein
C6N21_RS06785	COG0437	4 iron, 4 sulfur cluster binding
C6N21_RS06795	COG3062	negative regulation of establishment of protein localization
C6N21_RS06800	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6N21_RS06800	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6N21_RS06820	COG4615	Cyclic peptide transporter
C6N21_RS06825	COG3145	DNA-N1-methyladenine dioxygenase activity
C6N21_RS06830	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C6N21_RS06830	COG2169	Transcriptional regulator
C6N21_RS06835	COG1477	protein flavinylation
C6N21_RS06840	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C6N21_RS06855	COG0642	Histidine kinase
C6N21_RS06855	COG2198	Histidine kinase
C6N21_RS06860	COG2197	response regulator
C6N21_RS06865	COG2205	protein histidine kinase activity
C6N21_RS06865	COG0784	Response regulator, receiver
C6N21_RS06870	COG3852	Histidine kinase
C6N21_RS06875	COG2204	response regulator
C6N21_RS06880	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C6N21_RS06885	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C6N21_RS06890	COG2031	fatty acid transporter
C6N21_RS06895	COG0183	Belongs to the thiolase family
C6N21_RS06900	COG4676	Protein conserved in bacteria
C6N21_RS06905	COG5445	Predicted secreted protein (DUF2300)
C6N21_RS06910	COG2373	Large extracellular alpha-helical protein
C6N21_RS06915	COG3234	Protein of unknown function (DUF1175)
C6N21_RS06920	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
C6N21_RS06925	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C6N21_RS06935	COG3468	outer membrane autotransporter barrel domain protein
C6N21_RS06945	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C6N21_RS06950	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C6N21_RS06955	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C6N21_RS06960	COG3642	lipopolysaccharide core region biosynthetic process
C6N21_RS06965	COG0583	DNA-binding transcription factor activity
C6N21_RS06970	COG0584	glycerophosphoryl diester phosphodiesterase
C6N21_RS06975	COG2271	Major facilitator Superfamily
C6N21_RS06980	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C6N21_RS06990	COG0247	lactate metabolic process
C6N21_RS06995	COG5464	transposase or invertase
C6N21_RS07000	COG3836	Belongs to the HpcH HpaI aldolase family
C6N21_RS07005	COG2271	Major facilitator Superfamily
C6N21_RS07015	COG1414	Transcriptional regulator
C6N21_RS07080	COG0318	PFAM AMP-dependent synthetase and ligase
C6N21_RS07090	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C6N21_RS07105	COG1169	isochorismate synthase
C6N21_RS07110	COG4575	ribosome binding
C6N21_RS07115	COG2153	protein acetylation
C6N21_RS07145	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C6N21_RS07150	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C6N21_RS07160	COG0839	Belongs to the complex I subunit 6 family
C6N21_RS07175	COG1034	ATP synthesis coupled electron transport
C6N21_RS07180	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
C6N21_RS07185	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
C6N21_RS07205	COG0583	DNA-binding transcription factor activity
C6N21_RS07215	COG0436	Aminotransferase
C6N21_RS07225	COG0471	metal ion transport
C6N21_RS07225	COG0490	domain, Protein
C6N21_RS07230	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C6N21_RS07245	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C6N21_RS07250	COG0857	belongs to the CobB CobQ family
C6N21_RS07250	COG0280	phosphate acetyltransferase
C6N21_RS07255	COG1288	antiporter activity
C6N21_RS07260	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
C6N21_RS07265	COG0622	Phosphoesterase
C6N21_RS07270	COG0625	glutathione transferase activity
C6N21_RS07275	COG0625	glutathione transferase activity
C6N21_RS07280	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C6N21_RS07285	COG1090	epimerase
C6N21_RS07290	COG5464	transposase or invertase
C6N21_RS07295	COG4598	ABC transporter
C6N21_RS07300	COG4160	amino acid transport
C6N21_RS07305	COG4215	(ABC) transporter
C6N21_RS07310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6N21_RS07315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6N21_RS07320	COG0163	prenyltransferase activity
C6N21_RS07325	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C6N21_RS07330	COG1286	toxin biosynthetic process
C6N21_RS07335	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
C6N21_RS07340	COG0285	dihydrofolate synthase activity
C6N21_RS07350	COG0586	Pfam SNARE associated Golgi protein
C6N21_RS07360	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C6N21_RS07375	COG2814	Major facilitator Superfamily
C6N21_RS07385	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C6N21_RS07400	COG3101	peptidyl-lysine hydroxylation
C6N21_RS07405	COG0730	response to heat
C6N21_RS07420	COG2890	protein-(glutamine-N5) methyltransferase activity
C6N21_RS07435	COG3539	Fimbrial protein
C6N21_RS07440	COG3539	Fimbrial protein
C6N21_RS07445	COG3539	Fimbrial protein
C6N21_RS07450	COG3121	Chaperone
C6N21_RS07460	COG3539	Fimbrial protein
C6N21_RS07465	COG2062	phosphohistidine phosphatase, SixA
C6N21_RS07480	COG3691	Protein conserved in bacteria
C6N21_RS07490	COG2067	long-chain fatty acid transport protein
C6N21_RS07505	COG2853	Lipoprotein
C6N21_RS07515	COG2116	formate transmembrane transporter activity
C6N21_RS07675	COG3772	lysozyme
C6N21_RS08000	COG0583	DNA-binding transcription factor activity
C6N21_RS08005	COG2610	gluconate transmembrane transporter activity
C6N21_RS08015	COG0477	Major facilitator Superfamily
C6N21_RS08020	COG1566	PFAM secretion protein HlyD family protein
C6N21_RS08025	COG2197	response regulator
C6N21_RS08030	COG2205	protein histidine kinase activity
C6N21_RS08030	COG2198	Histidine kinase
C6N21_RS08030	COG0784	Response regulator, receiver
C6N21_RS08030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6N21_RS08035	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C6N21_RS08040	COG0679	Auxin Efflux Carrier
C6N21_RS08045	COG0028	Belongs to the TPP enzyme family
C6N21_RS08075	COG1560	Kdo2-lipid A biosynthetic process
C6N21_RS08085	COG0436	Aminotransferase
C6N21_RS08090	COG3275	phosphorelay sensor kinase activity
C6N21_RS08095	COG3279	Response regulator of the LytR AlgR family
C6N21_RS08100	COG2207	Transcriptional regulator
C6N21_RS08110	COG1363	Peptidase, m42
C6N21_RS08115	COG0006	proline dipeptidase activity
C6N21_RS08120	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6N21_RS08125	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6N21_RS08150	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C6N21_RS08155	COG2200	EAL domain
C6N21_RS08155	COG2199	diguanylate cyclase activity
C6N21_RS08170	COG3415	Transposase
C6N21_RS08175	COG3415	Transposase
C6N21_RS08205	COG0583	DNA-binding transcription factor activity
C6N21_RS08210	COG0385	Bile acid
C6N21_RS08215	COG3530	Putative quorum-sensing-regulated virulence factor
C6N21_RS08235	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C6N21_RS08240	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6N21_RS08245	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C6N21_RS08250	COG2190	(PTS) system
C6N21_RS08265	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C6N21_RS08270	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C6N21_RS08275	COG4208	sulfate ABC transporter
C6N21_RS08280	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
C6N21_RS08285	COG4150	thiosulfate binding
C6N21_RS08295	COG1028	Short-chain dehydrogenase reductase Sdr
C6N21_RS08310	COG1263	PTS System
C6N21_RS08310	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6N21_RS08315	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C6N21_RS08320	COG2837	iron assimilation
C6N21_RS08340	COG0860	N-Acetylmuramoyl-L-alanine amidase
C6N21_RS08350	COG2207	Transcriptional regulator
C6N21_RS08355	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
C6N21_RS08360	COG4816	utilization protein
C6N21_RS08370	COG4303	Ethanolamine ammonia lyase large subunit
C6N21_RS08375	COG4819	ethanolamine utilization protein
C6N21_RS08380	COG3192	ethanolamine utilization protein
C6N21_RS08385	COG1454	alcohol dehydrogenase
C6N21_RS08390	COG4820	ethanolamine utilization protein (EutJ)
C6N21_RS08395	COG1012	belongs to the aldehyde dehydrogenase family
C6N21_RS08400	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
C6N21_RS08405	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
C6N21_RS08410	COG0280	phosphate acetyltransferase
C6N21_RS08415	COG4812	Cobalamin adenosyltransferase
C6N21_RS08420	COG4766	ethanolamine catabolic process
C6N21_RS08425	COG4917	ethanolamine utilization protein
C6N21_RS08430	COG4810	utilization protein
C6N21_RS08440	COG0280	phosphate acetyltransferase
C6N21_RS08440	COG0281	malic enzyme
C6N21_RS08445	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C6N21_RS08450	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C6N21_RS08455	COG5342	invasion associated locus B
C6N21_RS08465	COG0493	'glutamate synthase
C6N21_RS08465	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6N21_RS08470	COG3850	Histidine kinase
C6N21_RS08475	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C6N21_RS08490	COG1393	Belongs to the ArsC family
C6N21_RS08510	COG1444	tRNA N-acetyltransferase activity
C6N21_RS08515	COG2321	neutral zinc metallopeptidase
C6N21_RS08535	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
C6N21_RS08545	COG2716	regulation of RNA biosynthetic process
C6N21_RS08550	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C6N21_RS08555	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6N21_RS08565	COG0650	Formate hydrogenlyase subunit 4
C6N21_RS08570	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C6N21_RS08580	COG4237	Hydrogenase 4 membrane
C6N21_RS08585	COG0651	ATP synthesis coupled electron transport
C6N21_RS08590	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
C6N21_RS08590	COG3261	NADH dehydrogenase
C6N21_RS08595	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C6N21_RS08600	COG3260	NADH ubiquinone oxidoreductase 20
C6N21_RS08610	COG3604	Transcriptional regulator
C6N21_RS08615	COG2116	formate transmembrane transporter activity
C6N21_RS08625	COG0628	permease
C6N21_RS08630	COG4783	chaperone-mediated protein folding
C6N21_RS08635	COG1393	Belongs to the ArsC family
C6N21_RS08645	COG2233	PERMEase
C6N21_RS08665	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C6N21_RS08670	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
C6N21_RS08675	COG0248	Ppx GppA phosphatase
C6N21_RS08680	COG2200	EAL domain
C6N21_RS08700	COG3133	Outer membrane lipoprotein
C6N21_RS08715	COG0516	GMP reductase activity
C6N21_RS08715	COG0517	IMP dehydrogenase activity
C6N21_RS08725	COG1645	bacterial-type flagellum-dependent swarming motility
C6N21_RS08740	COG2976	Protein conserved in bacteria
C6N21_RS08775	COG4953	penicillin-binding protein 1C
C6N21_RS08780	COG2373	Large extracellular alpha-helical protein
C6N21_RS08785	COG2897	thiosulfate sulfurtransferase activity
C6N21_RS08800	COG2975	iron-sulfur cluster assembly
C6N21_RS08805	COG0633	Ferredoxin
C6N21_RS08825	COG0822	iron-sulfur transferase activity
C6N21_RS08845	COG0483	inositol monophosphate 1-phosphatase activity
C6N21_RS08850	COG1073	alpha beta
C6N21_RS08855	COG3711	transcriptional antiterminator
C6N21_RS08860	COG2814	Major facilitator Superfamily
C6N21_RS08865	COG0583	DNA-binding transcription factor activity
C6N21_RS08870	COG4638	Rieske (2fe-2S)
C6N21_RS08895	COG2259	Doxx family
C6N21_RS08900	COG2017	converts alpha-aldose to the beta-anomer
C6N21_RS08905	COG1063	alcohol dehydrogenase
C6N21_RS08910	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6N21_RS08915	COG1129	ABC transporter
C6N21_RS08920	COG1879	ABC-type sugar transport system periplasmic component
C6N21_RS08925	COG0457	Tetratricopeptide repeat
C6N21_RS08930	COG1940	carbohydrate kinase activity
C6N21_RS08940	COG1017	nitric oxide dioxygenase activity
C6N21_RS08940	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C6N21_RS08945	COG0347	Belongs to the P(II) protein family
C6N21_RS08950	COG2204	response regulator
C6N21_RS08955	COG3170	Tfp pilus assembly protein FimV
C6N21_RS08960	COG2205	protein histidine kinase activity
C6N21_RS08965	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C6N21_RS08965	COG0047	phosphoribosylformylglycinamidine synthase activity
C6N21_RS08980	COG0560	Phosphoserine phosphatase
C6N21_RS08985	COG1737	Transcriptional regulator
C6N21_RS08990	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6N21_RS09015	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
C6N21_RS09040	COG0681	Belongs to the peptidase S26 family
C6N21_RS09050	COG3086	response to oxidative stress
C6N21_RS09055	COG3026	antisigma factor binding
C6N21_RS09060	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
C6N21_RS09065	COG1595	DNA-templated transcription, initiation
C6N21_RS09070	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C6N21_RS09080	COG0513	Belongs to the DEAD box helicase family
C6N21_RS09085	COG0583	DNA-binding transcription factor activity
C6N21_RS09105	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C6N21_RS09115	COG3118	belongs to the thioredoxin family
C6N21_RS09120	COG3148	PFAM DTW domain containing protein
C6N21_RS09125	COG1042	CoA-binding domain protein
C6N21_RS09125	COG0045	succinate-CoA ligase (ADP-forming) activity
C6N21_RS09125	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C6N21_RS09130	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C6N21_RS09135	COG5544	Lipoprotein
C6N21_RS09140	COG0477	Major facilitator Superfamily
C6N21_RS09170	COG0542	response to heat
C6N21_RS09180	COG0564	pseudouridine synthase activity
C6N21_RS09185	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C6N21_RS09195	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C6N21_RS09205	COG1605	Chorismate mutase
C6N21_RS09205	COG0077	Prephenate dehydratase
C6N21_RS09210	COG1605	Chorismate mutase
C6N21_RS09210	COG0287	Prephenate dehydrogenase
C6N21_RS09215	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C6N21_RS09235	COG2885	chlorophyll binding
C6N21_RS09260	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C6N21_RS09265	COG4137	Cytochrome C assembly protein
C6N21_RS09270	COG4536	flavin adenine dinucleotide binding
C6N21_RS09290	COG0497	DNA recombination
C6N21_RS09295	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C6N21_RS09305	COG2867	negative regulation of translational initiation
C6N21_RS09350	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6N21_RS09365	COG2032	superoxide dismutase activity
C6N21_RS09485	COG3772	lysozyme
C6N21_RS09620	COG4974	Belongs to the 'phage' integrase family
C6N21_RS09690	COG4983	Phage plasmid primase, P4 family domain protein
C6N21_RS09710	COG4372	Transposase
C6N21_RS09715	COG3436	PFAM IS66 Orf2 family protein
C6N21_RS09720	COG4372	Transposase
C6N21_RS09725	COG3436	PFAM IS66 Orf2 family protein
C6N21_RS09790	COG1358	cellular component organization or biogenesis
C6N21_RS09825	COG4372	Transposase
C6N21_RS09870	COG0254	rRNA binding
C6N21_RS09895	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C6N21_RS09900	COG2194	sulfuric ester hydrolase activity
C6N21_RS09940	COG0804	urea catabolic process
C6N21_RS09990	COG3436	PFAM IS66 Orf2 family protein
C6N21_RS09995	COG4372	Transposase
C6N21_RS10085	COG2003	Belongs to the UPF0758 family
C6N21_RS10125	COG0366	Alpha amylase catalytic
C6N21_RS10135	COG0579	oxidoreductase
C6N21_RS10140	COG1012	belongs to the aldehyde dehydrogenase family
C6N21_RS10145	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C6N21_RS10150	COG1113	amino acid transport
C6N21_RS10155	COG1802	Transcriptional regulator
C6N21_RS10160	COG1652	LysM domain
C6N21_RS10165	COG0401	homolog of Blt101
C6N21_RS10170	COG0640	Transcriptional regulator
C6N21_RS10175	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C6N21_RS10180	COG2916	Histone family protein nucleoid-structuring protein H-NS
C6N21_RS10195	COG4575	ribosome binding
C6N21_RS10200	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C6N21_RS10210	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C6N21_RS10215	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C6N21_RS10220	COG4175	Glycine betaine
C6N21_RS10225	COG4176	ABC-type proline glycine betaine transport system permease component
C6N21_RS10230	COG2113	Glycine betaine
C6N21_RS10235	COG2814	Major facilitator Superfamily
C6N21_RS10240	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
C6N21_RS10250	COG1846	Transcriptional regulator
C6N21_RS10255	COG1566	PFAM secretion protein HlyD family protein
C6N21_RS10260	COG2814	Major facilitator Superfamily
C6N21_RS10275	COG1238	metal cluster binding
C6N21_RS10280	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C6N21_RS10310	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
C6N21_RS10330	COG1546	Belongs to the CinA family
C6N21_RS10335	COG2951	lytic endotransglycosylase activity
C6N21_RS10340	COG3730	PTS system glucitol sorbitol-specific
C6N21_RS10345	COG3732	PTS system glucitol sorbitol-specific
C6N21_RS10355	COG1028	Short-chain dehydrogenase reductase Sdr
C6N21_RS10360	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6N21_RS10365	COG1349	DNA-binding transcription factor activity
C6N21_RS10390	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
C6N21_RS10395	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6N21_RS10400	COG1609	Transcriptional regulator
C6N21_RS10405	COG1263	PTS System
C6N21_RS10405	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6N21_RS10410	COG2723	6-phospho-beta-galactosidase activity
C6N21_RS10415	COG5499	transcription regulator containing HTH domain
C6N21_RS10420	COG4680	protein conserved in bacteria
C6N21_RS10430	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C6N21_RS10440	COG3260	NADH ubiquinone oxidoreductase 20
C6N21_RS10445	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C6N21_RS10450	COG3261	NADH dehydrogenase
C6N21_RS10450	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
C6N21_RS10455	COG0650	Formate hydrogenlyase subunit 4
C6N21_RS10460	COG0651	ATP synthesis coupled electron transport
C6N21_RS10465	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6N21_RS10475	COG0375	protein maturation
C6N21_RS10480	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
C6N21_RS10485	COG0298	carbon dioxide binding
C6N21_RS10490	COG0409	Hydrogenase expression formation protein
C6N21_RS10495	COG0309	Hydrogenase expression formation protein (HypE)
C6N21_RS10500	COG3604	Transcriptional regulator
C6N21_RS10515	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C6N21_RS10520	COG1349	DNA-binding transcription factor activity
C6N21_RS10525	COG2084	Dehydrogenase
C6N21_RS10530	COG3395	kinase activity
C6N21_RS10535	COG0235	Class ii aldolase
C6N21_RS10540	COG3622	Belongs to the hyi family
C6N21_RS10545	COG2610	gluconate transmembrane transporter activity
C6N21_RS10555	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C6N21_RS10570	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C6N21_RS10575	COG1388	LysM domain
C6N21_RS10575	COG4942	peptidase
C6N21_RS10630	COG2234	aminopeptidase activity
C6N21_RS10635	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6N21_RS10640	COG1518	maintenance of DNA repeat elements
C6N21_RS10655	COG1857	crispr-associated protein
C6N21_RS10700	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C6N21_RS10710	COG0720	synthase
C6N21_RS10715	COG0644	oxidoreductase
C6N21_RS10720	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C6N21_RS10725	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
C6N21_RS10730	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C6N21_RS10735	COG2086	electron transfer activity
C6N21_RS10740	COG0477	Major facilitator Superfamily
C6N21_RS10745	COG0277	FAD linked oxidase domain protein
C6N21_RS10750	COG1028	Short-chain dehydrogenase reductase Sdr
C6N21_RS10755	COG2223	nitrite transmembrane transporter activity
C6N21_RS10760	COG1070	Carbohydrate kinase
C6N21_RS10765	COG0602	queuosine metabolic process
C6N21_RS10790	COG3956	TIGRFAM MazG family protein
C6N21_RS10795	COG2337	Toxic component of a toxin-antitoxin (TA) module
C6N21_RS10800	COG2336	PFAM SpoVT AbrB
C6N21_RS10805	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C6N21_RS10815	COG3437	response regulator, receiver
C6N21_RS10815	COG4999	Histidine kinase
C6N21_RS10815	COG2205	protein histidine kinase activity
C6N21_RS10815	COG3850	Histidine kinase
C6N21_RS10820	COG4948	Mandelate Racemase Muconate Lactonizing
C6N21_RS10825	COG4948	Mandelate Racemase Muconate Lactonizing
C6N21_RS10830	COG2271	Major facilitator Superfamily
C6N21_RS10835	COG0716	FMN binding
C6N21_RS10840	COG0564	pseudouridine synthase activity
C6N21_RS10845	COG3098	single-species biofilm formation
C6N21_RS10860	COG1611	Belongs to the LOG family
C6N21_RS10865	COG0814	amino acid
C6N21_RS10870	COG1760	l-serine dehydratase
C6N21_RS10880	COG1454	alcohol dehydrogenase
C6N21_RS10885	COG0235	Class ii aldolase
C6N21_RS10890	COG0738	Major facilitator superfamily
C6N21_RS10900	COG1070	Carbohydrate kinase
C6N21_RS10910	COG1349	DNA-binding transcription factor activity
C6N21_RS10920	COG2363	Small membrane protein
C6N21_RS10925	COG0583	DNA-binding transcription factor activity
C6N21_RS10935	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C6N21_RS10940	COG2166	iron-sulfur cluster assembly
C6N21_RS10945	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C6N21_RS10950	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
C6N21_RS10975	COG0860	N-Acetylmuramoyl-L-alanine amidase
C6N21_RS10985	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C6N21_RS10985	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C6N21_RS10990	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C6N21_RS10995	COG1074	ATP-dependent DNA helicase activity
C6N21_RS11005	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
C6N21_RS11020	COG4795	General secretion pathway protein
C6N21_RS11025	COG2165	general secretion pathway protein
C6N21_RS11040	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
C6N21_RS11055	COG0861	Integral membrane protein TerC family
C6N21_RS11065	COG0667	Aldo Keto reductase
C6N21_RS11080	COG1609	Transcriptional regulator
C6N21_RS11090	COG0583	DNA-binding transcription factor activity
C6N21_RS11095	COG1794	racemase activity, acting on amino acids and derivatives
C6N21_RS11100	COG2814	Major facilitator Superfamily
C6N21_RS11105	COG1028	Short-chain dehydrogenase reductase Sdr
C6N21_RS11115	COG0183	Belongs to the thiolase family
C6N21_RS11120	COG0814	amino acid
C6N21_RS11140	COG4942	peptidase
C6N21_RS11150	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C6N21_RS11155	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C6N21_RS11160	COG2080	2 iron, 2 sulfur cluster binding
C6N21_RS11165	COG3829	transcription factor binding
C6N21_RS11170	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C6N21_RS11175	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C6N21_RS11180	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C6N21_RS11190	COG0549	Belongs to the carbamate kinase family
C6N21_RS11195	COG3608	succinylglutamate desuccinylase aspartoacylase
C6N21_RS11195	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C6N21_RS11200	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C6N21_RS11205	COG2068	MobA-Related Protein
C6N21_RS11210	COG0493	'glutamate synthase
C6N21_RS11210	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6N21_RS11215	COG0402	S-adenosylhomocysteine deaminase activity
C6N21_RS11220	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C6N21_RS11225	COG2080	2 iron, 2 sulfur cluster binding
C6N21_RS11225	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C6N21_RS11230	COG2233	PERMEase
C6N21_RS11235	COG0402	S-adenosylhomocysteine deaminase activity
C6N21_RS11240	COG2252	PERMEase
C6N21_RS11245	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6N21_RS11250	COG0493	'glutamate synthase
C6N21_RS11250	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6N21_RS11260	COG2233	PERMEase
C6N21_RS11285	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C6N21_RS11290	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C6N21_RS11295	COG4974	Belongs to the 'phage' integrase family
C6N21_RS11300	COG0716	FMN binding
C6N21_RS11310	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
C6N21_RS11320	COG1272	protein, Hemolysin III
C6N21_RS11330	COG2723	6-phospho-beta-galactosidase activity
C6N21_RS11335	COG1028	Short-chain dehydrogenase reductase Sdr
C6N21_RS11355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C6N21_RS11360	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C6N21_RS11365	COG0006	proline dipeptidase activity
C6N21_RS11390	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C6N21_RS11410	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C6N21_RS11430	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C6N21_RS11430	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C6N21_RS11435	COG1703	isobutyryl-CoA mutase activity
C6N21_RS11440	COG1024	Enoyl-CoA hydratase
C6N21_RS11445	COG0427	acetyl-CoA hydrolase
C6N21_RS11450	COG0583	DNA-binding transcription factor activity
C6N21_RS11455	COG2968	Membrane
C6N21_RS11465	COG0668	transmembrane transport
C6N21_RS11475	COG0191	fructose-bisphosphate aldolase activity
C6N21_RS11510	COG1122	ATPase activity
C6N21_RS11515	COG1122	ATPase activity
C6N21_RS11520	COG1072	(Pantothenic acid kinase))
C6N21_RS11530	COG1494	fructose-1,6-bisphosphatase
C6N21_RS11535	COG1063	alcohol dehydrogenase
C6N21_RS11540	COG2213	PTS system mannitol-specific
C6N21_RS11545	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6N21_RS11550	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C6N21_RS11555	COG0501	Belongs to the peptidase M48B family
C6N21_RS11570	COG1166	arginine decarboxylase activity
C6N21_RS11595	COG2814	Major facilitator Superfamily
C6N21_RS11605	COG2356	endonuclease I
C6N21_RS11610	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C6N21_RS11615	COG0189	ligase activity
C6N21_RS11630	COG2805	Type II/IV secretion system protein
C6N21_RS11635	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C6N21_RS11640	COG0762	integral membrane protein
C6N21_RS11655	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C6N21_RS11660	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C6N21_RS11665	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
C6N21_RS11680	COG0252	asparaginase activity
C6N21_RS11690	COG3171	Protein conserved in bacteria
C6N21_RS11705	COG1194	a g-specific adenine glycosylase
C6N21_RS11720	COG2211	Major facilitator Superfamily
C6N21_RS11725	COG1982	Orn Lys Arg decarboxylase major
C6N21_RS11735	COG1811	Na channel or pump
C6N21_RS11745	COG0582	viral genome integration into host DNA
C6N21_RS11750	COG4372	Transposase
C6N21_RS11760	COG3436	PFAM IS66 Orf2 family protein
C6N21_RS11765	COG4372	Transposase
C6N21_RS11790	COG3436	PFAM IS66 Orf2 family protein
C6N21_RS11800	COG2003	Belongs to the UPF0758 family
C6N21_RS11845	COG3436	PFAM IS66 Orf2 family protein
C6N21_RS12130	COG2003	Belongs to the UPF0758 family
C6N21_RS12165	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
C6N21_RS12195	COG2165	general secretion pathway protein
C6N21_RS12200	COG1459	type II secretion system
C6N21_RS12205	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C6N21_RS12225	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
C6N21_RS12240	COG1620	l-lactate permease
C6N21_RS12245	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C6N21_RS12250	COG3193	protein, possibly involved in utilization of glycolate and propanediol
C6N21_RS12255	COG0247	lactate metabolic process
C6N21_RS12265	COG0277	FAD linked oxidase domain protein
C6N21_RS12270	COG2186	Transcriptional regulator
C6N21_RS12275	COG0456	acetyltransferase
C6N21_RS12285	COG0318	PFAM AMP-dependent synthetase and ligase
C6N21_RS12325	COG0795	lipopolysaccharide-transporting ATPase activity
C6N21_RS12330	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
C6N21_RS12340	COG2244	polysaccharide biosynthetic process
C6N21_RS12345	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C6N21_RS12350	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C6N21_RS12355	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C6N21_RS12360	COG0306	phosphate transporter
C6N21_RS12365	COG0754	glutathionylspermidine amidase activity
C6N21_RS12370	COG0625	glutathione transferase activity
C6N21_RS12375	COG0298	carbon dioxide binding
C6N21_RS12385	COG1773	rubredoxin
C6N21_RS12390	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C6N21_RS12395	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
C6N21_RS12400	COG5557	Pfam Polysulphide reductase, NrfD
C6N21_RS12405	COG0437	4 iron, 4 sulfur cluster binding
C6N21_RS12410	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
C6N21_RS12430	COG0667	Aldo Keto reductase
C6N21_RS12440	COG1028	Short-chain dehydrogenase reductase Sdr
C6N21_RS12445	COG0848	biopolymer transport protein
C6N21_RS12450	COG0811	peptide transport
C6N21_RS12460	COG0626	cystathionine gamma-synthase activity
C6N21_RS12465	COG0586	Pfam SNARE associated Golgi protein
C6N21_RS12470	COG2207	Transcriptional regulator
C6N21_RS12475	COG1979	alcohol dehydrogenase
C6N21_RS12480	COG0656	L-ascorbic acid biosynthetic process
C6N21_RS12495	COG4238	major outer membrane lipoprotein
C6N21_RS12500	COG1032	radical SAM domain protein
C6N21_RS12505	COG2132	Multicopper oxidase
C6N21_RS12510	COG0204	Acyl-transferase
C6N21_RS12515	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C6N21_RS12525	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
C6N21_RS12530	COG3111	PFAM Bacterial OB fold (BOF) protein
C6N21_RS12535	COG0745	RESPONSE REGULATOR receiver
C6N21_RS12540	COG0642	Histidine kinase
C6N21_RS12555	COG2249	NAD(P)H dehydrogenase (quinone) activity
C6N21_RS12560	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C6N21_RS12565	COG0187	DNA topoisomerase II activity
C6N21_RS12570	COG3150	esterase
C6N21_RS12575	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C6N21_RS12580	COG3151	Protein conserved in bacteria
C6N21_RS12585	COG0494	nUDIX hydrolase
C6N21_RS12590	COG1538	Outer membrane efflux protein
C6N21_RS12605	COG0754	glutathionylspermidine amidase activity
C6N21_RS12610	COG3384	dioxygenase
C6N21_RS12630	COG2960	long-chain fatty acid transporting porin activity
C6N21_RS12635	COG3539	Fimbrial protein
C6N21_RS12640	COG3188	usher protein
C6N21_RS12660	COG3539	Fimbrial protein
C6N21_RS12670	COG1585	Membrane protein implicated in regulation of membrane protease activity
C6N21_RS12675	COG2268	Band 7 protein
C6N21_RS12710	COG3025	triphosphatase activity
C6N21_RS12720	COG4991	sh3 domain protein
C6N21_RS12735	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C6N21_RS12745	COG0583	DNA-binding transcription factor activity
C6N21_RS12755	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C6N21_RS12760	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C6N21_RS12765	COG0471	metal ion transport
C6N21_RS12780	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C6N21_RS12795	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C6N21_RS12810	COG2375	cellular response to nickel ion
C6N21_RS12820	COG1695	Transcriptional regulator
C6N21_RS12825	COG0840	transmembrane signaling receptor activity
C6N21_RS12840	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C6N21_RS12850	COG1609	Transcriptional regulator
C6N21_RS12855	COG3250	beta-galactosidase activity
C6N21_RS12860	COG2731	YhcH YjgK YiaL family protein
C6N21_RS12865	COG0531	amino acid
C6N21_RS12875	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
C6N21_RS12875	COG3408	Glycogen debranching enzyme
C6N21_RS12880	COG1902	pentaerythritol trinitrate reductase activity
C6N21_RS12880	COG0446	pyridine nucleotide-disulphide oxidoreductase
C6N21_RS12885	COG5499	transcription regulator containing HTH domain
C6N21_RS12890	COG4680	protein conserved in bacteria
C6N21_RS12905	COG1451	nucleotide metabolic process
C6N21_RS12910	COG2949	membrane
C6N21_RS12915	COG0673	inositol 2-dehydrogenase activity
C6N21_RS12920	COG0861	Integral membrane protein TerC family
C6N21_RS12925	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
C6N21_RS12935	COG2721	sulfolactate sulfo-lyase activity
C6N21_RS12945	COG2271	Major facilitator Superfamily
C6N21_RS12975	COG2186	Transcriptional regulator
C6N21_RS12980	COG0586	Pfam SNARE associated Golgi protein
C6N21_RS12990	COG1422	Protein of unknown function (DUF1090)
C6N21_RS12995	COG4575	ribosome binding
C6N21_RS13000	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
C6N21_RS13010	COG2259	Doxx family
C6N21_RS13015	COG0435	Glutathione S-transferase
C6N21_RS13020	COG3152	Membrane
C6N21_RS13025	COG3152	Membrane
C6N21_RS13035	COG0583	DNA-binding transcription factor activity
C6N21_RS13040	COG1741	Belongs to the pirin family
C6N21_RS13055	COG0814	amino acid
C6N21_RS13065	COG1760	l-serine dehydratase
C6N21_RS13070	COG0251	oxidation-reduction process
C6N21_RS13075	COG1882	Formate acetyltransferase
C6N21_RS13080	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C6N21_RS13090	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C6N21_RS13100	COG0583	DNA-binding transcription factor activity
C6N21_RS13125	COG1929	Belongs to the glycerate kinase type-1 family
C6N21_RS13130	COG2084	Dehydrogenase
C6N21_RS13140	COG2271	Major facilitator Superfamily
C6N21_RS13145	COG2721	sulfolactate sulfo-lyase activity
C6N21_RS13150	COG2002	toxin-antitoxin pair type II binding
C6N21_RS13160	COG1349	DNA-binding transcription factor activity
C6N21_RS13175	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6N21_RS13185	COG3716	PTS system mannose fructose sorbose family IID component
C6N21_RS13190	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6N21_RS13195	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C6N21_RS13200	COG2222	sugar isomerase
C6N21_RS13210	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6N21_RS13215	COG3715	PTS system
C6N21_RS13220	COG3716	PTS system mannose fructose sorbose family IID component
C6N21_RS13225	COG0363	glucosamine-6-phosphate deaminase activity
C6N21_RS13230	COG3539	Fimbrial protein
C6N21_RS13235	COG3121	Chaperone
C6N21_RS13240	COG3188	usher protein
C6N21_RS13245	COG3539	Fimbrial protein
C6N21_RS13250	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C6N21_RS13270	COG2823	Periplasmic or secreted lipoprotein
C6N21_RS13275	COG0701	Predicted permease
C6N21_RS13280	COG0702	epimerase
C6N21_RS13285	COG0693	protein deglycase activity
C6N21_RS13300	COG3153	acetyltransferase
C6N21_RS13305	COG3154	lipid carrier protein
C6N21_RS13310	COG0826	peptidase U32
C6N21_RS13315	COG0826	peptidase U32
C6N21_RS13320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C6N21_RS13325	COG0814	amino acid
C6N21_RS13330	COG0513	Belongs to the DEAD box helicase family
C6N21_RS13370	COG0195	Participates in both transcription termination and antitermination
C6N21_RS13390	COG2194	sulfuric ester hydrolase activity
C6N21_RS13400	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C6N21_RS13410	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C6N21_RS13415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C6N21_RS13425	COG1534	Rna-binding protein
C6N21_RS13430	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C6N21_RS13445	COG0697	spore germination
C6N21_RS13460	COG0142	geranyltranstransferase activity
C6N21_RS13465	COG3423	Transcriptional regulator
C6N21_RS13475	COG5007	Belongs to the BolA IbaG family
C6N21_RS13480	COG3113	response to antibiotic
C6N21_RS13485	COG2854	intermembrane phospholipid transfer
C6N21_RS13490	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C6N21_RS13495	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C6N21_RS13500	COG1127	ABC transporter
C6N21_RS13505	COG0530	calcium, potassium:sodium antiporter activity
C6N21_RS13510	COG0517	IMP dehydrogenase activity
C6N21_RS13510	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C6N21_RS13515	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
C6N21_RS13520	COG3117	lipopolysaccharide transmembrane transporter activity
C6N21_RS13525	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
C6N21_RS13530	COG1137	ATPase activity
C6N21_RS13535	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C6N21_RS13540	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C6N21_RS13555	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6N21_RS13560	COG0515	serine threonine protein kinase
C6N21_RS13570	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
C6N21_RS13575	COG5002	protein histidine kinase activity
C6N21_RS13575	COG2198	Histidine kinase
C6N21_RS13575	COG0784	Response regulator, receiver
C6N21_RS13580	COG1242	4 iron, 4 sulfur cluster binding
C6N21_RS13595	COG0070	glutamate synthase
C6N21_RS13595	COG0069	glutamate synthase activity
C6N21_RS13595	COG0067	glutamate synthase
C6N21_RS13600	COG0493	'glutamate synthase
C6N21_RS13605	COG4804	nuclease activity
C6N21_RS13610	COG2731	YhcH YjgK YiaL family protein
C6N21_RS13645	COG3069	C4-dicarboxylate transmembrane transporter activity
C6N21_RS13650	COG2969	positive regulation of protein catabolic process
C6N21_RS13655	COG0625	glutathione transferase activity
C6N21_RS13675	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
C6N21_RS13680	COG3105	Protein conserved in bacteria
C6N21_RS13685	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C6N21_RS13690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C6N21_RS13710	COG2732	(Barnase) inhibitor
C6N21_RS13730	COG0583	DNA-binding transcription factor activity
C6N21_RS13735	COG0312	modulator of DNA gyrase
C6N21_RS13740	COG3164	Protein of unknown function
C6N21_RS13745	COG1530	ribonuclease E activity
C6N21_RS13755	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C6N21_RS13760	COG1792	Involved in formation and maintenance of cell shape
C6N21_RS13765	COG1077	Cell shape determining protein MreB Mrl
C6N21_RS13785	COG0604	alcohol dehydrogenase
C6N21_RS13800	COG0511	ligase activity, forming carbon-carbon bonds
C6N21_RS13805	COG0439	Biotin carboxylase
C6N21_RS13810	COG3924	membrane
C6N21_RS13815	COG4145	pantothenate transmembrane transporter activity
C6N21_RS13825	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C6N21_RS13835	COG2189	Belongs to the N(4) N(6)-methyltransferase family
C6N21_RS13845	COG1309	transcriptional regulator
C6N21_RS13855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6N21_RS13860	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C6N21_RS13875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6N21_RS13880	COG4597	amino acid ABC transporter
C6N21_RS13885	COG0765	amino acid transport
C6N21_RS13890	COG1126	abc transporter atp-binding protein
C6N21_RS13930	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C6N21_RS13950	COG0551	DNA topoisomerase type I activity
C6N21_RS13960	COG0758	DNA mediated transformation
C6N21_RS13980	COG0569	domain protein
C6N21_RS13990	COG3036	rescue of stalled ribosome
C6N21_RS13995	COG0789	Transcriptional regulator
C6N21_RS14035	COG0201	protein transport
C6N21_RS14125	COG0089	rRNA binding
C6N21_RS14205	COG2964	Protein conserved in bacteria
C6N21_RS14210	COG0545	Peptidyl-prolyl cis-trans isomerase
C6N21_RS14220	COG1047	Peptidyl-prolyl cis-trans
C6N21_RS14225	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
C6N21_RS14245	COG0488	(ABC) transporter
C6N21_RS14250	COG0429	hydrolase of the alpha beta-hydrolase fold
C6N21_RS14260	COG3954	Phosphoribulokinase
C6N21_RS14265	COG1765	OsmC-like protein
C6N21_RS14275	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C6N21_RS14280	COG1289	transmembrane transporter activity
C6N21_RS14285	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C6N21_RS14290	COG0512	Glutamine amidotransferase of anthranilate synthase
C6N21_RS14295	COG2184	nucleotidyltransferase activity
C6N21_RS14305	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C6N21_RS14315	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C6N21_RS14320	COG2146	nitrite reductase [NAD(P)H] activity
C6N21_RS14325	COG2116	formate transmembrane transporter activity
C6N21_RS14350	COG0531	amino acid
C6N21_RS14355	COG2222	sugar isomerase
C6N21_RS14365	COG1082	Xylose isomerase domain protein TIM barrel
C6N21_RS14375	COG2188	Transcriptional regulator
C6N21_RS14395	COG1735	metal-dependent hydrolase with the TIM-barrel fold
C6N21_RS14400	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
C6N21_RS14405	COG3457	Alanine racemase
C6N21_RS14415	COG2188	Transcriptional regulator
C6N21_RS14420	COG0180	Tryptophanyl-tRNA synthetase
C6N21_RS14430	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C6N21_RS14435	COG0338	D12 class N6 adenine-specific DNA methyltransferase
C6N21_RS14440	COG3266	domain, Protein
C6N21_RS14460	COG4796	Type ii and iii secretion system protein
C6N21_RS14475	COG3166	PFAM Fimbrial assembly family protein
C6N21_RS14480	COG4972	Pilus assembly protein
C6N21_RS14485	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
C6N21_RS14490	COG0494	nUDIX hydrolase
C6N21_RS14500	COG1011	Hydrolase
C6N21_RS14505	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C6N21_RS14515	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
C6N21_RS14545	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C6N21_RS14550	COG2183	response to ionizing radiation
C6N21_RS14560	COG1918	ferrous iron import across plasma membrane
C6N21_RS14565	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
C6N21_RS14580	COG5464	transposase or invertase
C6N21_RS14600	COG2610	gluconate transmembrane transporter activity
C6N21_RS14605	COG1640	4-alpha-glucanotransferase
C6N21_RS14610	COG0058	SHG alpha-glucan phosphorylase activity
C6N21_RS14625	COG1690	Belongs to the RtcB family
C6N21_RS14630	COG4650	regulator
C6N21_RS14635	COG1349	DNA-binding transcription factor activity
C6N21_RS14650	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C6N21_RS14675	COG0058	SHG alpha-glucan phosphorylase activity
C6N21_RS14700	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C6N21_RS14705	COG2095	MarC family integral membrane protein
C6N21_RS14710	COG2610	gluconate transmembrane transporter activity
C6N21_RS14715	COG3265	gluconokinase activity
C6N21_RS14720	COG1609	Transcriptional regulator
C6N21_RS14725	COG1741	Belongs to the pirin family
C6N21_RS14730	COG0673	inositol 2-dehydrogenase activity
C6N21_RS14740	COG1247	-acetyltransferase
C6N21_RS14745	COG3157	Type VI secretion system effector, Hcp
C6N21_RS14765	COG0405	Gamma-glutamyltransferase
C6N21_RS14775	COG0584	glycerophosphoryl diester phosphodiesterase
C6N21_RS14780	COG3842	ATPase activity
C6N21_RS14785	COG0395	ABC-type sugar transport system, permease component
C6N21_RS14790	COG1175	transmembrane transport
C6N21_RS14795	COG1653	transport
C6N21_RS14800	COG0410	ABC transporter
C6N21_RS14805	COG0411	ABC transporter
C6N21_RS14810	COG4177	L-phenylalanine transmembrane transporter activity
C6N21_RS14815	COG0559	Belongs to the binding-protein-dependent transport system permease family
C6N21_RS14820	COG0683	leucine binding
C6N21_RS14825	COG0456	acetyltransferase
C6N21_RS14830	COG0683	leucine binding
C6N21_RS14835	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C6N21_RS14840	COG2177	Part of the ABC transporter FtsEX involved in
C6N21_RS14845	COG2884	Cell division ATP-binding protein ftsE
C6N21_RS14850	COG0552	protein localization to endoplasmic reticulum
C6N21_RS14855	COG0742	ribosomal rna small subunit methyltransferase
C6N21_RS14860	COG3776	membrane
C6N21_RS14870	COG3714	YhhN family
C6N21_RS14885	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C6N21_RS14900	COG0628	permease
C6N21_RS14905	COG2091	lysine biosynthetic process via aminoadipic acid
C6N21_RS14910	COG0747	negative chemotaxis
C6N21_RS14915	COG0601	transmembrane transport
C6N21_RS14920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C6N21_RS14925	COG0444	Belongs to the ABC transporter superfamily
C6N21_RS14950	COG0842	Transport permease protein
C6N21_RS14955	COG0842	Transport permease protein
C6N21_RS14955	COG1129	ABC transporter
C6N21_RS14960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6N21_RS14985	COG2081	HI0933 family
C6N21_RS14990	COG0306	phosphate transporter
C6N21_RS15000	COG0589	response to stress
C6N21_RS15010	COG3104	oligopeptide transport
C6N21_RS15020	COG0339	signal peptide processing
C6N21_RS15025	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
C6N21_RS15030	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C6N21_RS15045	COG0640	Transcriptional regulator
C6N21_RS15050	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C6N21_RS15055	COG1393	Belongs to the ArsC family
C6N21_RS15075	COG3065	identical protein binding
C6N21_RS15085	COG2197	response regulator
C6N21_RS15090	COG1285	pathogenesis
C6N21_RS15105	COG3247	response to pH
C6N21_RS15110	COG2771	luxR family
C6N21_RS15120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6N21_RS15125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C6N21_RS15135	COG2207	Transcriptional regulator
C6N21_RS15145	COG0076	glutamate decarboxylase activity
C6N21_RS15150	COG1858	cytochrome C peroxidase
C6N21_RS15160	COG2197	response regulator
C6N21_RS15165	COG0583	DNA-binding transcription factor activity
C6N21_RS15170	COG1295	ribonuclease BN
C6N21_RS15175	COG0477	Major facilitator Superfamily
C6N21_RS15180	COG2982	Protein involved in outer membrane biogenesis
C6N21_RS15185	COG2200	EAL domain
C6N21_RS15200	COG0612	Peptidase, M16
C6N21_RS15215	COG2199	diguanylate cyclase activity
C6N21_RS15215	COG2200	EAL domain
C6N21_RS15220	COG3118	belongs to the thioredoxin family
C6N21_RS15220	COG0457	Tetratricopeptide repeat
C6N21_RS15225	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
C6N21_RS15230	COG1215	transferase activity, transferring glycosyl groups
C6N21_RS15235	COG1215	transferase activity, transferring glycosyl groups
C6N21_RS15260	COG2194	sulfuric ester hydrolase activity
C6N21_RS15290	COG0814	amino acid
C6N21_RS15295	COG4608	Belongs to the ABC transporter superfamily
C6N21_RS15300	COG0444	Belongs to the ABC transporter superfamily
C6N21_RS15305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C6N21_RS15310	COG0601	transmembrane transport
C6N21_RS15320	COG0747	negative chemotaxis
C6N21_RS15335	COG2194	sulfuric ester hydrolase activity
C6N21_RS15340	COG2223	nitrite transmembrane transporter activity
C6N21_RS15350	COG5571	outer membrane autotransporter
C6N21_RS15355	COG2818	Glycosylase
C6N21_RS15360	COG0456	acetyltransferase
C6N21_RS15365	COG0243	molybdopterin cofactor binding
C6N21_RS15370	COG2885	chlorophyll binding
C6N21_RS15385	COG2944	sequence-specific DNA binding
C6N21_RS15390	COG1278	Cold shock
C6N21_RS15415	COG3274	enterobacterial common antigen metabolic process
C6N21_RS15420	COG4682	membrane
C6N21_RS15425	COG4682	membrane
C6N21_RS15430	COG1070	Carbohydrate kinase
C6N21_RS15440	COG4213	ABC transporter substrate-binding protein
C6N21_RS15450	COG4214	carbohydrate transport
C6N21_RS15455	COG2207	Transcriptional regulator
C6N21_RS15455	COG1609	Transcriptional regulator
C6N21_RS15460	COG2992	FlgJ-related protein
C6N21_RS15465	COG0366	Alpha amylase catalytic
C6N21_RS15470	COG3977	Valine--pyruvate aminotransferase
C6N21_RS15475	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6N21_RS15480	COG1414	Transcriptional regulator
C6N21_RS15490	COG2731	YhcH YjgK YiaL family protein
C6N21_RS15495	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
C6N21_RS15500	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
C6N21_RS15505	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C6N21_RS15510	COG1070	Carbohydrate kinase
C6N21_RS15515	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
C6N21_RS15520	COG3623	hexulose-6-phosphate isomerase
C6N21_RS15525	COG0235	Class ii aldolase
C6N21_RS15535	COG3713	MltA-interacting MipA family protein
C6N21_RS15540	COG0583	DNA-binding transcription factor activity
C6N21_RS15545	COG1566	PFAM secretion protein HlyD family protein
C6N21_RS15560	COG1012	belongs to the aldehyde dehydrogenase family
C6N21_RS15565	COG1454	alcohol dehydrogenase
C6N21_RS15570	COG3276	selenocysteine insertion sequence binding
C6N21_RS15580	COG0625	glutathione transferase activity
C6N21_RS15585	COG3209	COG3209 Rhs family protein
C6N21_RS15600	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C6N21_RS15620	COG1566	PFAM secretion protein HlyD family protein
C6N21_RS15630	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6N21_RS15630	COG2213	PTS system mannitol-specific
C6N21_RS15640	COG3722	fumarate hydratase activity
C6N21_RS15665	COG5295	Hep Hag repeat protein
C6N21_RS15675	COG1620	l-lactate permease
C6N21_RS15680	COG2186	Transcriptional regulator
C6N21_RS15690	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C6N21_RS15695	COG1045	serine acetyltransferase
C6N21_RS15710	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C6N21_RS15715	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C6N21_RS15730	COG4942	peptidase
C6N21_RS15735	COG2861	carbohydrate metabolic process
C6N21_RS15740	COG1216	Glycosyl transferase, family 2
C6N21_RS15750	COG0156	8-amino-7-oxononanoate synthase activity
C6N21_RS15760	COG0859	PFAM glycosyl transferase family 9
C6N21_RS15765	COG0859	PFAM glycosyl transferase family 9
C6N21_RS15770	COG3307	-O-antigen
C6N21_RS15775	COG1216	Glycosyl transferase, family 2
C6N21_RS15780	COG1442	glycosyl transferase family 8
C6N21_RS15785	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C6N21_RS15800	COG0515	serine threonine protein kinase
C6N21_RS15805	COG0438	transferase activity, transferring glycosyl groups
C6N21_RS15810	COG0859	PFAM glycosyl transferase family 9
C6N21_RS15815	COG1519	Transferase
C6N21_RS15845	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C6N21_RS15875	COG1561	YicC-like family, N-terminal region
C6N21_RS15880	COG3645	SOS response
C6N21_RS15885	COG2860	membrane
C6N21_RS15895	COG0194	GDP metabolic process
C6N21_RS15905	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C6N21_RS15910	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C6N21_RS15915	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C6N21_RS15925	COG0786	glutamate:sodium symporter activity
C6N21_RS15930	COG2233	PERMEase
C6N21_RS15935	COG2982	Protein involved in outer membrane biogenesis
C6N21_RS15940	COG1501	Belongs to the glycosyl hydrolase 31 family
C6N21_RS15945	COG2211	Major facilitator Superfamily
C6N21_RS15960	COG2814	Major facilitator Superfamily
C6N21_RS15965	COG0697	spore germination
C6N21_RS15970	COG1464	Belongs to the NlpA lipoprotein family
C6N21_RS16000	COG2252	PERMEase
C6N21_RS16010	COG2271	Major facilitator Superfamily
C6N21_RS16015	COG2271	Major facilitator Superfamily
C6N21_RS16020	COG3851	Histidine kinase
C6N21_RS16025	COG2197	response regulator
C6N21_RS16030	COG0440	acetolactate synthase activity
C6N21_RS16035	COG0028	Belongs to the TPP enzyme family
C6N21_RS16070	COG2814	Major facilitator Superfamily
C6N21_RS16075	COG0641	radical SAM
C6N21_RS16085	COG2149	membrane
C6N21_RS16095	COG3119	arylsulfatase activity
C6N21_RS16100	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C6N21_RS16105	COG2207	Transcriptional regulator
C6N21_RS16120	COG2188	Transcriptional regulator
C6N21_RS16140	COG5645	(Lipo)protein
C6N21_RS16145	COG0823	Involved in the tonB-independent uptake of proteins
C6N21_RS16155	COG2271	Major facilitator Superfamily
C6N21_RS16165	COG0800	Aldolase
C6N21_RS16170	COG3734	2-keto-3-deoxy-galactonokinase
C6N21_RS16175	COG2186	Transcriptional regulator
C6N21_RS16185	COG0561	phosphatase activity
C6N21_RS16190	COG3753	Protein conserved in bacteria
C6N21_RS16195	COG0187	DNA topoisomerase II activity
C6N21_RS16205	COG0592	DNA-directed DNA polymerase activity
C6N21_RS16255	COG0814	amino acid
C6N21_RS16270	COG2091	lysine biosynthetic process via aminoadipic acid
C6N21_RS16275	COG0431	NADPH-dependent FMN reductase
C6N21_RS16280	COG2252	PERMEase
C6N21_RS16285	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C6N21_RS16305	COG3436	PFAM IS66 Orf2 family protein
C6N21_RS16310	COG4372	Transposase
C6N21_RS16320	COG0363	glucosamine-6-phosphate deaminase activity
C6N21_RS16325	COG2382	esterase
C6N21_RS16335	COG2723	6-phospho-beta-galactosidase activity
C6N21_RS16340	COG1263	PTS System
C6N21_RS16340	COG2190	(PTS) system
C6N21_RS16340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6N21_RS16345	COG3711	transcriptional antiterminator
C6N21_RS16350	COG0704	Plays a role in the regulation of phosphate uptake
C6N21_RS16355	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C6N21_RS16360	COG0581	inorganic phosphate transmembrane transporter activity
C6N21_RS16365	COG0573	inorganic phosphate transmembrane transporter activity
C6N21_RS16370	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C6N21_RS16395	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C6N21_RS16450	COG3312	ion transport
C6N21_RS16465	COG0716	FMN binding
C6N21_RS16470	COG1522	sequence-specific DNA binding
C6N21_RS16500	COG1129	ABC transporter
C6N21_RS16505	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6N21_RS16510	COG1879	ABC-type sugar transport system periplasmic component
C6N21_RS16515	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6N21_RS16520	COG1609	Transcriptional regulator
C6N21_RS16525	COG0477	Major facilitator Superfamily
C6N21_RS16530	COG2186	Transcriptional regulator
C6N21_RS16570	COG3085	chromosome segregation
C6N21_RS16600	COG3978	acetolactate synthase activity
C6N21_RS16605	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C6N21_RS16615	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C6N21_RS16620	COG0583	DNA-binding transcription factor activity
C6N21_RS16630	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C6N21_RS16635	COG3692	DNA binding
C6N21_RS16640	COG0210	DNA helicase
C6N21_RS16660	COG3118	belongs to the thioredoxin family
C6N21_RS16670	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C6N21_RS16680	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C6N21_RS16685	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
C6N21_RS16690	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C6N21_RS16695	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
C6N21_RS16700	COG1088	dTDP-glucose 4,6-dehydratase activity
C6N21_RS16705	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C6N21_RS16710	COG0456	acetyltransferase
C6N21_RS16715	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C6N21_RS16720	COG2244	polysaccharide biosynthetic process
C6N21_RS16740	COG1113	amino acid transport
C6N21_RS16765	COG0641	radical SAM
C6N21_RS16770	COG3071	HemY protein
C6N21_RS16775	COG2959	enzyme of heme biosynthesis
C6N21_RS16780	COG1587	Uroporphyrinogen-III synthase
C6N21_RS16795	COG3072	Adenylate cyclase
C6N21_RS16805	COG5567	small periplasmic lipoprotein
C6N21_RS16815	COG3159	Protein conserved in bacteria
C6N21_RS16825	COG1011	Hydrolase
C6N21_RS16830	COG0210	DNA helicase
C6N21_RS16835	COG3698	Phosphodiester glycosidase
C6N21_RS16840	COG0598	Magnesium transport protein CorA
C6N21_RS16870	COG2962	Rard protein
C6N21_RS16875	COG2050	protein possibly involved in aromatic compounds catabolism
C6N21_RS16880	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
C6N21_RS16885	COG0514	ATP-dependent DNA helicase (RecQ)
C6N21_RS16890	COG1280	lysine exporter protein (LysE YggA)
C6N21_RS16895	COG1280	lysine exporter protein (LysE YggA)
C6N21_RS16900	COG2267	carboxylic ester hydrolase activity
C6N21_RS16905	COG0561	phosphatase activity
C6N21_RS16910	COG0697	spore germination
C6N21_RS16915	COG0583	DNA-binding transcription factor activity
C6N21_RS16935	COG3157	Type VI secretion system effector, Hcp
C6N21_RS16940	COG0412	Dienelactone hydrolase
C6N21_RS16945	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
C6N21_RS16950	COG1322	Protein conserved in bacteria
C6N21_RS16960	COG3165	ubiquinone biosynthetic process from chorismate
C6N21_RS16970	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C6N21_RS16975	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C6N21_RS16980	COG0805	protein transport
C6N21_RS16990	COG0250	Participates in transcription elongation, termination and antitermination
C6N21_RS16995	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C6N21_RS17000	COG0543	2 iron, 2 sulfur cluster binding
C6N21_RS17020	COG1739	Uncharacterized protein family UPF0029
C6N21_RS17025	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C6N21_RS17030	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
C6N21_RS17060	COG1763	Mo-molybdopterin cofactor biosynthetic process
C6N21_RS17065	COG0746	molybdenum cofactor guanylyltransferase activity
C6N21_RS17070	COG3084	Protein conserved in bacteria
C6N21_RS17075	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C6N21_RS17080	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C6N21_RS17085	COG5339	Protein conserved in bacteria
C6N21_RS17090	COG0204	Acyl-transferase
C6N21_RS17100	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C6N21_RS17100	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C6N21_RS17115	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C6N21_RS17125	COG2204	response regulator
C6N21_RS17130	COG3852	Histidine kinase
C6N21_RS17135	COG0174	glutamine synthetase
C6N21_RS17145	COG1217	gtp-binding protein TYPA
C6N21_RS17150	COG1349	DNA-binding transcription factor activity
C6N21_RS17155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6N21_RS17165	COG3684	Belongs to the aldolase LacD family
C6N21_RS17170	COG1063	alcohol dehydrogenase
C6N21_RS17180	COG0477	Major facilitator Superfamily
C6N21_RS17190	COG1011	Hydrolase
C6N21_RS17205	COG0456	acetyltransferase
C6N21_RS17230	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
C6N21_RS17245	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C6N21_RS17250	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C6N21_RS17260	COG2864	formate dehydrogenase
C6N21_RS17265	COG0437	4 iron, 4 sulfur cluster binding
C6N21_RS17290	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6N21_RS17290	COG3711	transcriptional antiterminator
C6N21_RS17295	COG1363	Peptidase, m42
C6N21_RS17300	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6N21_RS17300	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6N21_RS17305	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6N21_RS17345	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C6N21_RS17365	COG2258	MOSC domain
C6N21_RS17370	COG2205	protein histidine kinase activity
C6N21_RS17375	COG0745	RESPONSE REGULATOR receiver
C6N21_RS17380	COG3678	ATP-independent chaperone mediated protein folding
C6N21_RS17395	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C6N21_RS17415	COG3152	Membrane
C6N21_RS17420	COG3691	Protein conserved in bacteria
C6N21_RS17425	COG0589	response to stress
C6N21_RS17435	COG1494	fructose-1,6-bisphosphatase
C6N21_RS17445	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C6N21_RS17460	COG1575	Belongs to the MenA family. Type 1 subfamily
C6N21_RS17475	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C6N21_RS17480	COG1609	Transcriptional regulator
C6N21_RS17485	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C6N21_RS17495	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
C6N21_RS17505	COG0626	cystathionine gamma-synthase activity
C6N21_RS17510	COG0460	homoserine dehydrogenase
C6N21_RS17510	COG0527	aspartate kinase activity
C6N21_RS17515	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C6N21_RS17525	COG0697	spore germination
C6N21_RS17530	COG3738	Protein conserved in bacteria
C6N21_RS17535	COG0371	Dehydrogenase
C6N21_RS17540	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C6N21_RS17545	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6N21_RS17545	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6N21_RS17545	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C6N21_RS17550	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6N21_RS17555	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6N21_RS17560	COG1882	Formate acetyltransferase
C6N21_RS17565	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C6N21_RS17570	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6N21_RS17575	COG2207	Transcriptional regulator
C6N21_RS17580	COG2194	sulfuric ester hydrolase activity
C6N21_RS17595	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C6N21_RS17610	COG0583	DNA-binding transcription factor activity
C6N21_RS17670	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
C6N21_RS17670	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
C6N21_RS17715	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C6N21_RS17720	COG0250	Participates in transcription elongation, termination and antitermination
C6N21_RS17765	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
C6N21_RS17780	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C6N21_RS17820	COG3068	Protein conserved in bacteria
C6N21_RS17835	COG3678	ATP-independent chaperone mediated protein folding
C6N21_RS17845	COG4191	Histidine kinase
C6N21_RS17850	COG2204	response regulator
C6N21_RS17855	COG0151	Belongs to the GarS family
C6N21_RS17890	COG0456	acetyltransferase
C6N21_RS17900	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C6N21_RS17905	COG2224	Isocitrate lyase
C6N21_RS17920	COG1414	Transcriptional regulator
C6N21_RS17925	COG1410	methionine synthase
C6N21_RS17925	COG0646	methionine synthase
C6N21_RS17930	COG1283	sodium-dependent phosphate transmembrane transporter activity
C6N21_RS17975	COG1187	pseudouridine synthase activity
C6N21_RS17985	COG0527	aspartate kinase activity
C6N21_RS18020	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C6N21_RS18035	COG0477	Major facilitator Superfamily
C6N21_RS18035	COG2814	Major facilitator Superfamily
C6N21_RS18040	COG3833	ABC-type maltose transport systems, permease component
C6N21_RS18045	COG1175	transmembrane transport
C6N21_RS18050	COG2182	Extracellular solute-binding protein
C6N21_RS18060	COG3842	ATPase activity
C6N21_RS18105	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C6N21_RS18115	COG0534	Mate efflux family protein
C6N21_RS18120	COG3237	CsbD-like
C6N21_RS18125	COG0735	belongs to the Fur family
C6N21_RS18135	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C6N21_RS18185	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
C6N21_RS18195	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
C6N21_RS18200	COG5532	Uncharacterized conserved protein (DUF2303)
C6N21_RS18230	COG3646	Phage regulatory protein
C6N21_RS18250	COG1484	DNA-dependent DNA replication
C6N21_RS18255	COG0305	Participates in initiation and elongation during chromosome replication
C6N21_RS18265	COG1403	HNH endonuclease
C6N21_RS18330	COG3772	lysozyme
C6N21_RS18365	COG4220	transposase activity
C6N21_RS18385	COG1030	water channel activity
C6N21_RS18470	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6N21_RS18530	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C6N21_RS18545	COG0305	Participates in initiation and elongation during chromosome replication
C6N21_RS18555	COG1448	Aminotransferase
C6N21_RS18565	COG3700	Belongs to the class B bacterial acid phosphatase family
C6N21_RS18570	COG0432	Pfam Uncharacterised protein family UPF0047
C6N21_RS18575	COG2315	Protein conserved in bacteria
C6N21_RS18580	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C6N21_RS18590	COG0629	single-stranded DNA binding
C6N21_RS18605	COG4943	cyclic-guanylate-specific phosphodiesterase activity
C6N21_RS18610	COG2207	Transcriptional regulator
C6N21_RS18615	COG0789	Transcriptional regulator
C6N21_RS18635	COG2252	PERMEase
C6N21_RS18640	COG0025	NhaP-type Na H and K H
C6N21_RS18655	COG3162	membrane
C6N21_RS18660	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C6N21_RS18675	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
C6N21_RS18680	COG0437	4 iron, 4 sulfur cluster binding
C6N21_RS18685	COG3301	Polysulphide reductase, NrfD
C6N21_RS18695	COG3088	subunit of a heme lyase
C6N21_RS18700	COG4235	cytochrome complex assembly
C6N21_RS18710	COG1301	dicarboxylic acid transport
C6N21_RS18715	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C6N21_RS18730	COG1289	transmembrane transporter activity
C6N21_RS18735	COG1566	PFAM secretion protein HlyD family protein
C6N21_RS18745	COG2015	COG2015, Alkyl sulfatase and related hydrolases
C6N21_RS18750	COG1940	carbohydrate kinase activity
C6N21_RS18755	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C6N21_RS18760	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6N21_RS18765	COG1129	ABC transporter
C6N21_RS18770	COG1879	ABC-type sugar transport system periplasmic component
C6N21_RS18775	COG1737	Transcriptional regulator
C6N21_RS18785	COG0698	ribose 5-phosphate isomerase
C6N21_RS18795	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C6N21_RS18800	COG0456	acetyltransferase
C6N21_RS18805	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
C6N21_RS18810	COG3454	Phosphonate metabolism
C6N21_RS18815	COG4778	phosphonate C-P lyase system protein PhnL
C6N21_RS18820	COG4107	phosphonate C-P lyase system protein PhnK
C6N21_RS18825	COG3627	carbon phosphorus lyase activity
C6N21_RS18830	COG3626	phosphonate metabolism
C6N21_RS18835	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
C6N21_RS18840	COG3624	Phosphonate C-P lyase system protein PhnG
C6N21_RS18845	COG2188	Transcriptional regulator
C6N21_RS18850	COG3639	organic phosphonate transmembrane transporter activity
C6N21_RS18855	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
C6N21_RS18865	COG2764	glyoxalase bleomycin resistance protein dioxygenase
C6N21_RS18870	COG2824	Alkylphosphonate utilization operon protein PhnA
C6N21_RS18890	COG0477	Major facilitator Superfamily
C6N21_RS18900	COG0642	Histidine kinase
C6N21_RS18905	COG0745	RESPONSE REGULATOR receiver
C6N21_RS18910	COG2194	sulfuric ester hydrolase activity
C6N21_RS18915	COG0531	amino acid
C6N21_RS18920	COG2207	Transcriptional regulator
C6N21_RS18925	COG1982	Orn Lys Arg decarboxylase major
C6N21_RS18930	COG2169	Transcriptional regulator
C6N21_RS18935	COG1486	melibiose metabolic process
C6N21_RS18940	COG2211	Major facilitator Superfamily
C6N21_RS18950	COG3647	Membrane
C6N21_RS18955	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C6N21_RS18955	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C6N21_RS18960	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C6N21_RS18975	COG4565	transcriptional regulatory protein
C6N21_RS18980	COG3290	protein histidine kinase activity
C6N21_RS18985	COG3592	Divergent 4Fe-4S mono-cluster
C6N21_RS18990	COG2388	GCN5-related N-acetyl-transferase
C6N21_RS19010	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C6N21_RS19015	COG3104	oligopeptide transport
C6N21_RS19020	COG1982	Orn Lys Arg decarboxylase major
C6N21_RS19025	COG0531	amino acid
C6N21_RS19030	COG3710	Transcriptional regulator
C6N21_RS19035	COG4372	Transposase
C6N21_RS19040	COG3436	PFAM IS66 Orf2 family protein
C6N21_RS19145	COG3436	PFAM IS66 Orf2 family protein
C6N21_RS19165	COG0582	viral genome integration into host DNA
C6N21_RS19175	COG1309	transcriptional regulator
C6N21_RS19190	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C6N21_RS19195	COG1027	Aspartate ammonia-lyase
C6N21_RS19200	COG3030	protein affecting phage T7 exclusion by the F plasmid
C6N21_RS19205	COG0531	amino acid
C6N21_RS19230	COG1509	lysine 2,3-aminomutase activity
C6N21_RS19240	COG5510	response to toxic substance
C6N21_RS19245	COG5510	response to toxic substance
C6N21_RS19250	COG2076	Multidrug Resistance protein
C6N21_RS19255	COG3040	lipid binding
C6N21_RS19260	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C6N21_RS19275	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C6N21_RS19280	COG1053	succinate dehydrogenase
C6N21_RS19290	COG0531	amino acid
C6N21_RS19305	COG1511	domain protein
C6N21_RS19305	COG3264	Mechanosensitive ion channel
C6N21_RS19345	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C6N21_RS19350	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C6N21_RS19350	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C6N21_RS19355	COG0802	atpase or kinase
C6N21_RS19360	COG0860	N-Acetylmuramoyl-L-alanine amidase
C6N21_RS19380	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C6N21_RS19385	COG0330	HflC and HflK could
C6N21_RS19390	COG0330	HflC and HflK could
C6N21_RS19395	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
C6N21_RS19410	COG0557	exoribonuclease II activity
C6N21_RS19415	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C6N21_RS19425	COG3789	protein conserved in bacteria
C6N21_RS19430	COG1842	Phage shock protein A
C6N21_RS19440	COG3766	membrane
C6N21_RS19445	COG5463	Belongs to the UPF0441 family
C6N21_RS19450	COG0754	glutathionylspermidine amidase activity
C6N21_RS19455	COG1960	acyl-CoA dehydrogenase activity
C6N21_RS19465	COG3650	response to hydrogen peroxide
C6N21_RS19470	COG1073	alpha beta
C6N21_RS19485	COG3037	sugar-specific permease SgaT UlaA
C6N21_RS19530	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C6N21_RS19540	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C6N21_RS19550	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
C6N21_RS19555	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C6N21_RS19560	COG4670	ketone body catabolic process
C6N21_RS19565	COG1024	Enoyl-CoA hydratase
C6N21_RS19580	COG1309	transcriptional regulator
C6N21_RS19585	COG3061	Opacity-associated protein A
C6N21_RS19595	COG0545	Peptidyl-prolyl cis-trans isomerase
C6N21_RS19600	COG1113	amino acid transport
C6N21_RS19610	COG0697	spore germination
C6N21_RS19615	COG0702	epimerase
C6N21_RS19620	COG1733	regulation of RNA biosynthetic process
C6N21_RS19625	COG0737	Belongs to the 5'-nucleotidase family
C6N21_RS19630	COG1218	3'(2'),5'-bisphosphate nucleotidase
C6N21_RS19635	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
C6N21_RS19645	COG1253	flavin adenine dinucleotide binding
C6N21_RS19660	COG0729	surface antigen
C6N21_RS19665	COG2911	Protein conserved in bacteria
C6N21_RS19670	COG2105	PFAM AIG2 family protein
C6N21_RS19675	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
C6N21_RS19680	COG1879	ABC-type sugar transport system periplasmic component
C6N21_RS19685	COG1129	ABC transporter
C6N21_RS19690	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6N21_RS19695	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6N21_RS19705	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C6N21_RS19715	COG0312	modulator of DNA gyrase
C6N21_RS19720	COG3783	Cytochrome b(562)
C6N21_RS19725	COG0602	queuosine metabolic process
C6N21_RS19730	COG1328	CTP reductase activity
C6N21_RS19735	COG0366	Alpha amylase catalytic
C6N21_RS19740	COG1263	PTS System
C6N21_RS19740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6N21_RS19745	COG1609	Transcriptional regulator
C6N21_RS19755	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C6N21_RS19760	COG0251	oxidation-reduction process
C6N21_RS19785	COG0251	oxidation-reduction process
C6N21_RS19790	COG1028	Short-chain dehydrogenase reductase Sdr
C6N21_RS19795	COG1309	transcriptional regulator
C6N21_RS19800	COG2731	YhcH YjgK YiaL family protein
C6N21_RS19815	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
C6N21_RS19820	COG0456	acetyltransferase
C6N21_RS19830	COG0525	valine-tRNA ligase activity
C6N21_RS19835	COG2927	DNA polymerase III (CHI subunit)
C6N21_RS19845	COG0795	lipopolysaccharide-transporting ATPase activity
C6N21_RS19850	COG0795	lipopolysaccharide-transporting ATPase activity
C6N21_RS19855	COG0433	COG0433 Predicted ATPase
C6N21_RS19860	COG1609	Transcriptional regulator
C6N21_RS19865	COG2610	gluconate transmembrane transporter activity
C6N21_RS19870	COG1028	Short-chain dehydrogenase reductase Sdr
C6N21_RS19875	COG1063	alcohol dehydrogenase
C6N21_RS19880	COG3265	gluconokinase activity
C6N21_RS19885	COG1064	alcohol dehydrogenase
C6N21_RS19900	COG0515	serine threonine protein kinase
C6N21_RS19900	COG2815	serine threonine protein kinase
C6N21_RS19955	COG1401	restriction endodeoxyribonuclease activity
C6N21_RS19975	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
C6N21_RS19980	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
C6N21_RS19990	COG0582	viral genome integration into host DNA
C6N21_RS19995	COG4974	Belongs to the 'phage' integrase family
C6N21_RS20000	COG3539	Fimbrial protein
C6N21_RS20005	COG3539	Fimbrial protein
C6N21_RS20010	COG3121	Chaperone
C6N21_RS20015	COG3188	usher protein
C6N21_RS20020	COG3539	Fimbrial protein
C6N21_RS20025	COG3539	Fimbrial protein
C6N21_RS20030	COG3539	Fimbrial protein
C6N21_RS20050	COG0246	Mannitol dehydrogenase
C6N21_RS20060	COG2186	Transcriptional regulator
C6N21_RS20080	COG0583	DNA-binding transcription factor activity
C6N21_RS20085	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C6N21_RS20090	COG0700	Nucleoside recognition
C6N21_RS20095	COG3366	ferrous iron transmembrane transporter activity
C6N21_RS20110	COG0477	Major facilitator Superfamily
C6N21_RS20125	COG1924	4 iron, 4 sulfur cluster binding
C6N21_RS20130	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
C6N21_RS20135	COG2733	membrane
C6N21_RS20140	COG2814	Major facilitator Superfamily
C6N21_RS20150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C6N21_RS20155	COG5457	Domain of unknown function (DUF1127)
C6N21_RS20165	COG0523	cobalamin synthesis protein
C6N21_RS20170	COG2879	small protein
C6N21_RS20175	COG1966	Carbon starvation protein
C6N21_RS20185	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C6N21_RS20190	COG2368	4-hydroxyphenylacetate
C6N21_RS20210	COG3971	2-oxopent-4-enoate hydratase activity
C6N21_RS20220	COG3384	dioxygenase
C6N21_RS20225	COG1012	belongs to the aldehyde dehydrogenase family
C6N21_RS20230	COG0179	Fumarylacetoacetate (FAA) hydrolase
C6N21_RS20235	COG1846	Transcriptional regulator
C6N21_RS20240	COG0840	transmembrane signaling receptor activity
C6N21_RS20245	COG2271	Major facilitator Superfamily
C6N21_RS20250	COG1802	Transcriptional regulator
C6N21_RS20255	COG1063	alcohol dehydrogenase
C6N21_RS20270	COG1484	DNA-dependent DNA replication
C6N21_RS20285	COG2966	Psort location CytoplasmicMembrane, score
C6N21_RS20290	COG2197	response regulator
C6N21_RS20295	COG2197	response regulator
C6N21_RS20300	COG4114	ferric iron reductase
C6N21_RS20330	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
C6N21_RS20335	COG0456	acetyltransferase
C6N21_RS20340	COG1011	Hydrolase
C6N21_RS20375	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
C6N21_RS20410	COG3646	Phage regulatory protein
C6N21_RS20430	COG4725	Belongs to the MT-A70-like family
C6N21_RS20440	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C6N21_RS20455	COG1403	HNH endonuclease
C6N21_RS20525	COG3772	lysozyme
C6N21_RS20580	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6N21_RS20625	COG2823	Periplasmic or secreted lipoprotein
C6N21_RS20635	COG4667	esterase of the alpha-beta hydrolase superfamily
C6N21_RS20640	COG0084	hydrolase, TatD family'
C6N21_RS20645	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C6N21_RS20650	COG1328	CTP reductase activity
C6N21_RS20680	COG3726	membrane protein affecting hemolysin expression
C6N21_RS20685	COG0560	Phosphoserine phosphatase
C6N21_RS20690	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C6N21_RS20695	COG1056	cytidyltransferase-related domain
C6N21_RS20695	COG3172	ATPase kinase involved in NAD metabolism
C6N21_RS20700	COG0488	(ABC) transporter
C6N21_RS20710	COG0741	lytic transglycosylase activity
C6N21_RS20730	COG3708	Transcriptional regulator
C6N21_RS20730	COG2207	Transcriptional regulator
C6N21_RS20735	COG3045	CreA protein
C6N21_RS20740	COG0745	RESPONSE REGULATOR receiver
C6N21_RS20745	COG2205	protein histidine kinase activity
C6N21_RS20750	COG4452	Inner membrane protein CreD
C6N21_RS20755	COG0745	RESPONSE REGULATOR receiver
C6N21_RS20770	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
C6N21_RS20790	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C6N21_RS20805	COG1115	amino acid carrier protein
C6N21_RS20810	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C6N21_RS20815	COG0521	Mo-molybdopterin cofactor biosynthetic process
C6N21_RS20820	COG1584	GPR1 FUN34 yaaH family protein
C6N21_RS20825	COG4735	regulation of single-species biofilm formation
C6N21_RS20855	COG3119	arylsulfatase activity
C6N21_RS20870	COG0583	DNA-binding transcription factor activity
C6N21_RS20905	COG0196	riboflavin kinase activity
C6N21_RS20920	COG1047	Peptidyl-prolyl cis-trans
C6N21_RS20945	COG0505	Belongs to the CarA family
C6N21_RS20950	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C6N21_RS21005	COG0644	oxidoreductase
C6N21_RS21010	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C6N21_RS21015	COG2271	Major facilitator Superfamily
C6N21_RS21030	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C6N21_RS21055	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C6N21_RS21060	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
C6N21_RS21065	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
C6N21_RS21070	COG0564	pseudouridine synthase activity
C6N21_RS21080	COG0417	DNA replication proofreading
C6N21_RS21085	COG0235	Class ii aldolase
C6N21_RS21095	COG1069	ribulokinase activity
C6N21_RS21105	COG4977	sequence-specific DNA binding
C6N21_RS21110	COG0586	Pfam SNARE associated Golgi protein
C6N21_RS21120	COG1178	ABC-type Fe3 transport system permease component
C6N21_RS21125	COG4143	(ABC) transporter
C6N21_RS21140	COG2814	Major facilitator Superfamily
C6N21_RS21155	COG0473	3-isopropylmalate dehydrogenase activity
C6N21_RS21170	COG0583	DNA-binding transcription factor activity
C6N21_RS21175	COG0028	Belongs to the TPP enzyme family
C6N21_RS21180	COG0440	acetolactate synthase activity
C6N21_RS21190	COG1609	Transcriptional regulator
C6N21_RS21215	COG3116	cell division
C6N21_RS21220	COG0768	penicillin binding
C6N21_RS21225	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C6N21_RS21230	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C6N21_RS21245	COG0772	Belongs to the SEDS family
C6N21_RS21260	COG1181	Belongs to the D-alanine--D-alanine ligase family
C6N21_RS21265	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C6N21_RS21270	COG0849	cell division
C6N21_RS21275	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C6N21_RS21295	COG0494	nUDIX hydrolase
C6N21_RS21310	COG0237	dephospho-CoA kinase activity
C6N21_RS21320	COG1459	type II secretion system
C6N21_RS21325	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C6N21_RS21330	COG4969	Belongs to the N-Me-Phe pilin family
C6N21_RS21340	COG0157	Belongs to the NadC ModD family
C6N21_RS21345	COG3023	N-Acetylmuramoyl-L-alanine amidase
C6N21_RS21350	COG3725	Membrane protein required for beta-lactamase induction
C6N21_RS21355	COG1113	amino acid transport
C6N21_RS21360	COG2186	Transcriptional regulator
C6N21_RS21370	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
C6N21_RS21375	COG0508	dehydrogenase complex catalyzes the overall conversion of
C6N21_RS21380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C6N21_RS21385	COG3064	Membrane
C6N21_RS21395	COG1049	propionate catabolic process, 2-methylcitrate cycle
C6N21_RS21420	COG2132	Multicopper oxidase
C6N21_RS21425	COG4993	Dehydrogenase
C6N21_RS21430	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
C6N21_RS21435	COG0288	reversible hydration of carbon dioxide
C6N21_RS21440	COG1131	(ABC) transporter
C6N21_RS21445	COG0842	Transport permease protein
C6N21_RS21450	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6N21_RS21455	COG0726	polysaccharide deacetylase
C6N21_RS21470	COG5464	transposase or invertase
C6N21_RS21505	COG3539	Fimbrial protein
C6N21_RS21510	COG3539	Fimbrial protein
C6N21_RS21515	COG3539	Fimbrial protein
C6N21_RS21520	COG3188	usher protein
C6N21_RS21525	COG3121	Chaperone
C6N21_RS21530	COG3539	Fimbrial protein
C6N21_RS21535	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C6N21_RS21540	COG0617	tRNA 3'-terminal CCA addition
C6N21_RS21550	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C6N21_RS21560	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C6N21_RS21565	COG1643	Atp-dependent helicase
C6N21_RS21575	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C6N21_RS21585	COG1120	ATPase activity
C6N21_RS21590	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C6N21_RS21595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6N21_RS21615	COG2860	membrane
C6N21_RS21620	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C6N21_RS21640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C6N21_RS21645	COG3835	regulator
C6N21_RS21665	COG0024	Methionine aminopeptidase
C6N21_RS21700	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C6N21_RS21705	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C6N21_RS21710	COG0575	Belongs to the CDS family
C6N21_RS21715	COG0750	zinc metalloprotease
C6N21_RS21725	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
C6N21_RS21730	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C6N21_RS21755	COG0587	DNA-directed DNA polymerase activity
C6N21_RS21765	COG1982	Orn Lys Arg decarboxylase major
C6N21_RS21770	COG0346	lactoylglutathione lyase activity
C6N21_RS21780	COG4568	rho-dependent transcription termination
C6N21_RS21790	COG4681	YaeQ
C6N21_RS21795	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
C6N21_RS21800	COG3015	lipoprotein NlpE involved in copper resistance
C6N21_RS21815	COG1720	tRNA m6t6A37 methyltransferase activity
C6N21_RS21825	COG1464	Belongs to the NlpA lipoprotein family
C6N21_RS21830	COG2011	ABC-type metal ion transport system permease component
C6N21_RS21835	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C6N21_RS21840	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C6N21_RS21875	COG0656	L-ascorbic acid biosynthetic process
C6N21_RS21880	COG0583	DNA-binding transcription factor activity
C6N21_RS21890	COG2226	methyltransferase
C6N21_RS21895	COG0741	lytic transglycosylase activity
C6N21_RS21895	COG1388	LysM domain
C6N21_RS21905	COG2226	methyltransferase
C6N21_RS21915	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6N21_RS21945	COG3157	Type VI secretion system effector, Hcp
C6N21_RS22040	COG3209	COG3209 Rhs family protein
C6N21_RS22060	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C6N21_RS22070	COG1960	acyl-CoA dehydrogenase activity
C6N21_RS22080	COG0121	glutamine amidotransferase
C6N21_RS22085	COG3034	peptidoglycan biosynthetic process
C6N21_RS22090	COG3041	Addiction module toxin RelE StbE family
C6N21_RS22095	COG3077	Addiction module antitoxin, RelB DinJ family
C6N21_RS22100	COG0791	NLP P60 protein
C6N21_RS22130	COG0454	-acetyltransferase
C6N21_RS22140	COG1690	Belongs to the RtcB family
C6N21_RS22145	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
C6N21_RS22150	COG2195	Cleaves the N-terminal amino acid of tripeptides
C6N21_RS22170	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C6N21_RS22190	COG0583	DNA-binding transcription factor activity
C6N21_RS22195	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C6N21_RS22200	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C6N21_RS22205	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C6N21_RS22210	COG2080	2 iron, 2 sulfur cluster binding
C6N21_RS22225	COG0727	PFAM Uncharacterised protein family (UPF0153)
C6N21_RS22230	COG3121	Chaperone
C6N21_RS22240	COG3188	usher protein
C6N21_RS22295	COG1388	LysM domain
C6N21_RS22300	COG2207	Transcriptional regulator
C6N21_RS22300	COG3708	Transcriptional regulator
C6N21_RS22305	COG0656	L-ascorbic acid biosynthetic process
C6N21_RS22310	COG3059	membrane
C6N21_RS22320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C6N21_RS22325	COG2207	Transcriptional regulator
C6N21_RS22330	COG0247	lactate metabolic process
C6N21_RS22335	COG1139	Iron-sulfur cluster binding protein
C6N21_RS22340	COG1556	Lactate utilization protein
C6N21_RS22380	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C6N21_RS22390	COG2771	luxR family
C6N21_RS22390	COG2200	EAL domain
C6N21_RS22395	COG0583	DNA-binding transcription factor activity
C6N21_RS22410	COG0666	response to abiotic stimulus
C6N21_RS22420	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C6N21_RS22425	COG1304	FMN binding
C6N21_RS22430	COG0549	Belongs to the carbamate kinase family
C6N21_RS22435	COG0402	S-adenosylhomocysteine deaminase activity
C6N21_RS22450	COG1129	ABC transporter
C6N21_RS22455	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6N21_RS22465	COG1064	alcohol dehydrogenase
C6N21_RS22480	COG1280	lysine exporter protein (LysE YggA)
C6N21_RS22490	COG3829	transcription factor binding
C6N21_RS22495	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C6N21_RS22500	COG0372	Belongs to the citrate synthase family
C6N21_RS22505	COG2079	MmgE PrpD family protein
C6N21_RS22510	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C6N21_RS22515	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C6N21_RS22520	COG0402	S-adenosylhomocysteine deaminase activity
C6N21_RS22525	COG0583	DNA-binding transcription factor activity
C6N21_RS22530	COG0288	reversible hydration of carbon dioxide
C6N21_RS22540	COG2807	transmembrane transport
C6N21_RS22545	COG0110	maltose O-acetyltransferase activity
C6N21_RS22550	COG2223	nitrite transmembrane transporter activity
C6N21_RS22565	COG1609	Transcriptional regulator
C6N21_RS22570	COG1414	Transcriptional regulator
C6N21_RS22605	COG2814	Major facilitator Superfamily
C6N21_RS22610	COG3122	Protein conserved in bacteria
C6N21_RS22640	COG1215	transferase activity, transferring glycosyl groups
C6N21_RS22645	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C6N21_RS22655	COG4521	taurine ABC transporter
C6N21_RS22665	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C6N21_RS22670	COG2175	clavaminate synthase activity
C6N21_RS22675	COG0113	porphobilinogen synthase activity
C6N21_RS22685	COG3468	outer membrane autotransporter barrel domain protein
C6N21_RS22690	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C6N21_RS22695	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C6N21_RS22705	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
C6N21_RS22730	COG1181	Belongs to the D-alanine--D-alanine ligase family
C6N21_RS22745	COG1785	Belongs to the alkaline phosphatase family
C6N21_RS22755	COG3706	GGDEF domain
C6N21_RS22760	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C6N21_RS22785	COG4126	flavin adenine dinucleotide binding
C6N21_RS22815	COG2814	Major facilitator Superfamily
C6N21_RS22820	COG0419	ATPase involved in DNA repair
C6N21_RS22825	COG0420	3'-5' exonuclease activity
C6N21_RS22830	COG0745	RESPONSE REGULATOR receiver
C6N21_RS22835	COG5002	protein histidine kinase activity
C6N21_RS22840	COG1114	Component of the transport system for branched-chain amino acids
C6N21_RS22845	COG1113	amino acid transport
C6N21_RS22850	COG0366	Alpha amylase catalytic
C6N21_RS22870	COG1862	Preprotein translocase
C6N21_RS22875	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C6N21_RS22880	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C6N21_RS22885	COG1403	HNH endonuclease
C6N21_RS22890	COG3248	Nucleoside-binding outer membrane protein
C6N21_RS22895	COG4238	major outer membrane lipoprotein
C6N21_RS22905	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C6N21_RS22905	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C6N21_RS22920	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C6N21_RS22925	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C6N21_RS22930	COG0667	Aldo Keto reductase
C6N21_RS22940	COG0142	geranyltranstransferase activity
C6N21_RS22955	COG0693	protein deglycase activity
C6N21_RS22960	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C6N21_RS22970	COG2814	Major facilitator Superfamily
C6N21_RS22995	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C6N21_RS23000	COG1845	cytochrome c oxidase, subunit III
C6N21_RS23005	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C6N21_RS23010	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C6N21_RS23015	COG2223	nitrite transmembrane transporter activity
C6N21_RS23020	COG3056	Lipoprotein
C6N21_RS23025	COG0271	Belongs to the BolA IbaG family
C6N21_RS23050	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C6N21_RS23055	COG0776	regulation of translation
C6N21_RS23060	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C6N21_RS23065	COG1555	photosystem II stabilization
C6N21_RS23070	COG0824	Thioesterase
C6N21_RS23080	COG4533	DNA binding
C6N21_RS23090	COG1522	sequence-specific DNA binding
C6N21_RS23095	COG1132	(ABC) transporter
C6N21_RS23100	COG1132	(ABC) transporter
C6N21_RS23105	COG0347	Belongs to the P(II) protein family
C6N21_RS23110	COG0004	ammonium transporteR
C6N21_RS23115	COG1946	Acyl-CoA thioesterase
C6N21_RS23120	COG3126	Type III secretion system lipoprotein chaperone (YscW)
C6N21_RS23125	COG3695	enzyme binding
C6N21_RS23135	COG5507	3-demethylubiquinone-9 3-methyltransferase
C6N21_RS23140	COG4943	cyclic-guanylate-specific phosphodiesterase activity
C6N21_RS23150	COG0110	maltose O-acetyltransferase activity
C6N21_RS23165	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C6N21_RS23170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6N21_RS23175	COG1309	transcriptional regulator
C6N21_RS23185	COG1196	nuclear chromosome segregation
C6N21_RS23185	COG3264	Mechanosensitive ion channel
C6N21_RS23195	COG3923	Primosomal replication protein n
C6N21_RS23200	COG2832	Protein of unknown function (DUF454)
C6N21_RS23215	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C6N21_RS23255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6N21_RS23260	COG4651	solute:proton antiporter activity
C6N21_RS23260	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C6N21_RS23265	COG2223	nitrite transmembrane transporter activity
C6N21_RS23275	COG0737	Belongs to the 5'-nucleotidase family
C6N21_RS23290	COG3735	TraB family
C6N21_RS23300	COG3093	addiction module antidote protein HigA
C6N21_RS23305	COG2217	Heavy metal translocating P-type atpase
C6N21_RS23315	COG0531	amino acid
C6N21_RS23320	COG0789	Transcriptional regulator
C6N21_RS23325	COG1585	Membrane protein implicated in regulation of membrane protease activity
C6N21_RS23330	COG0330	HflC and HflK could
C6N21_RS23335	COG4619	ABC transporter
C6N21_RS23340	COG0390	transport system, permease component
C6N21_RS23345	COG3118	belongs to the thioredoxin family
C6N21_RS23350	COG0300	oxidoreductase activity
C6N21_RS23355	COG2755	lipolytic protein G-D-S-L family
C6N21_RS23360	COG4181	ATPase activity
C6N21_RS23365	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
C6N21_RS23370	COG3209	COG3209 Rhs family protein
C6N21_RS23390	COG0583	DNA-binding transcription factor activity
C6N21_RS23400	COG1414	Transcriptional regulator
C6N21_RS23405	COG3960	tartronate-semialdehyde synthase activity
C6N21_RS23410	COG3622	Belongs to the hyi family
C6N21_RS23415	COG2084	Dehydrogenase
C6N21_RS23420	COG1953	Uracil, thiamine, allantoin
C6N21_RS23430	COG2233	PERMEase
C6N21_RS23435	COG1929	Belongs to the glycerate kinase type-1 family
C6N21_RS23440	COG3257	ureidoglycine aminohydrolase activity
C6N21_RS23445	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C6N21_RS23450	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
C6N21_RS23455	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C6N21_RS23460	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C6N21_RS23470	COG0549	Belongs to the carbamate kinase family
C6N21_RS23475	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C6N21_RS23480	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C6N21_RS23495	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C6N21_RS23505	COG1988	membrane-bound metal-dependent
C6N21_RS23510	COG2501	S4 domain
C6N21_RS23520	COG3539	Fimbrial protein
C6N21_RS23530	COG3188	usher protein
C6N21_RS23535	COG3539	Fimbrial protein
C6N21_RS23540	COG3539	Fimbrial protein
C6N21_RS23545	COG2197	response regulator
C6N21_RS23555	COG0582	viral genome integration into host DNA
C6N21_RS23585	COG4220	transposase activity
C6N21_RS23605	COG1030	water channel activity
C6N21_RS23655	COG1196	nuclear chromosome segregation
C6N21_RS23705	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6N21_RS23710	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C6N21_RS23720	COG0500	methyltransferase
C6N21_RS23735	COG4571	Outer membrane protease
C6N21_RS23750	COG2207	Transcriptional regulator
C6N21_RS23765	COG4783	chaperone-mediated protein folding
C6N21_RS23770	COG1215	transferase activity, transferring glycosyl groups
C6N21_RS23775	COG5433	transposase activity
C6N21_RS23835	COG3501	Rhs element vgr protein
C6N21_RS23845	COG0745	RESPONSE REGULATOR receiver
C6N21_RS23855	COG1538	Outer membrane efflux protein
C6N21_RS23860	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6N21_RS23865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6N21_RS23870	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C6N21_RS23875	COG1113	amino acid transport
C6N21_RS23880	COG0668	transmembrane transport
C6N21_RS23885	COG0778	Nitroreductase
C6N21_RS23890	COG2315	Protein conserved in bacteria
C6N21_RS23925	COG2977	Belongs to the P-Pant transferase superfamily
C6N21_RS23930	COG4771	TonB-dependent receptor
C6N21_RS23940	COG2382	esterase
C6N21_RS23945	COG3251	PFAM MbtH domain protein
C6N21_RS23950	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C6N21_RS23950	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
C6N21_RS23955	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
C6N21_RS23960	COG1120	ATPase activity
C6N21_RS23965	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6N21_RS23970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6N21_RS23980	COG4592	Periplasmic binding protein
C6N21_RS23990	COG1169	isochorismate synthase
C6N21_RS23995	COG1021	2,3-dihydroxybenzoate-AMP ligase
C6N21_RS24000	COG3433	isochorismatase activity
C6N21_RS24000	COG1535	isochorismatase
C6N21_RS24005	COG1028	Short-chain dehydrogenase reductase Sdr
C6N21_RS24010	COG2050	protein possibly involved in aromatic compounds catabolism
C6N21_RS24015	COG1966	Carbon starvation protein
C6N21_RS24020	COG2879	small protein
C6N21_RS24025	COG0371	Dehydrogenase
C6N21_RS24030	COG0436	Aminotransferase
C6N21_RS24035	COG1475	DNA binding
C6N21_RS24040	COG3969	phosphoadenosine phosphosulfate
C6N21_RS24045	COG0583	DNA-binding transcription factor activity
C6N21_RS24050	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C6N21_RS24055	COG0450	alkyl hydroperoxide reductase
C6N21_RS24060	COG3634	alkyl hydroperoxide reductase activity
C6N21_RS24065	COG0589	response to stress
C6N21_RS24070	COG1063	alcohol dehydrogenase
C6N21_RS24080	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C6N21_RS24090	COG3719	Belongs to the RNase T2 family
C6N21_RS24095	COG0471	metal ion transport
C6N21_RS24110	COG3051	citrate lyase alpha subunit
C6N21_RS24115	COG2301	Belongs to the HpcH HpaI aldolase family
C6N21_RS24125	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
C6N21_RS24130	COG3290	protein histidine kinase activity
C6N21_RS24135	COG4565	transcriptional regulatory protein
C6N21_RS24140	COG3069	C4-dicarboxylate transmembrane transporter activity
C6N21_RS24165	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C6N21_RS24170	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C6N21_RS24185	COG0583	DNA-binding transcription factor activity
C6N21_RS24205	COG1686	Belongs to the peptidase S11 family
C6N21_RS24210	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C6N21_RS24215	COG0772	Belongs to the SEDS family
C6N21_RS24220	COG0768	penicillin binding
C6N21_RS24230	COG0799	negative regulation of ribosome biogenesis
C6N21_RS24245	COG1466	dna polymerase III delta subunit
C6N21_RS24260	COG2888	peptidyl-tyrosine sulfation
C6N21_RS24265	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C6N21_RS24275	COG2214	Heat shock protein DnaJ domain protein
C6N21_RS24280	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C6N21_RS24290	COG2214	Heat shock protein DnaJ domain protein
C6N21_RS24295	COG0443	Heat shock 70 kDa protein
C6N21_RS24305	COG1126	abc transporter atp-binding protein
C6N21_RS24310	COG0765	amino acid transport
C6N21_RS24315	COG0765	amino acid transport
C6N21_RS24320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6N21_RS24335	COG0815	Transfers the fatty acyl group on membrane lipoproteins
C6N21_RS24340	COG4535	Mg2 and Co2 transporter CorC
C6N21_RS24350	COG1702	phosphate starvation-inducible protein PhoH
C6N21_RS24360	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C6N21_RS24405	COG0367	asparagine synthase
C6N21_RS24415	COG0647	UMP catabolic process
C6N21_RS24425	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C6N21_RS24435	COG1263	PTS System
C6N21_RS24435	COG2190	(PTS) system
C6N21_RS24435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6N21_RS24455	COG0735	belongs to the Fur family
C6N21_RS24465	COG0716	FMN binding
C6N21_RS24475	COG0596	Alpha beta hydrolase
C6N21_RS24480	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
C6N21_RS24485	COG0033	Phosphoglucomutase
C6N21_RS24490	COG0531	amino acid
C6N21_RS24495	COG1982	Orn Lys Arg decarboxylase major
C6N21_RS24505	COG0745	RESPONSE REGULATOR receiver
C6N21_RS24510	COG2205	protein histidine kinase activity
C6N21_RS24605	COG3272	Protein of unknown function (DUF1722)
C6N21_RS24610	COG0415	Belongs to the DNA photolyase family
C6N21_RS24620	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C6N21_RS24625	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C6N21_RS24630	COG1984	allophanate hydrolase subunit 2
C6N21_RS24645	COG3180	Ammonia monooxygenase
C6N21_RS24650	COG3539	Fimbrial protein
C6N21_RS24655	COG3121	Chaperone
C6N21_RS24660	COG3188	usher protein
C6N21_RS24665	COG3539	Fimbrial protein
C6N21_RS24670	COG0372	Belongs to the citrate synthase family
C6N21_RS24685	COG2009	succinate dehydrogenase
C6N21_RS24690	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
C6N21_RS24695	COG1053	succinate dehydrogenase
C6N21_RS24700	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C6N21_RS24705	COG0567	Dehydrogenase, E1 component
C6N21_RS24710	COG0508	dehydrogenase complex catalyzes the overall conversion of
C6N21_RS24720	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C6N21_RS24725	COG2188	Transcriptional regulator
C6N21_RS24730	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6N21_RS24730	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6N21_RS24730	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6N21_RS24735	COG0383	alpha-mannosidase activity
C6N21_RS24745	COG1271	oxidase subunit
C6N21_RS24750	COG1294	oxidase, subunit
C6N21_RS24755	COG4890	Cyd operon protein YbgT
C6N21_RS24760	COG3790	cyd operon protein YbgE
C6N21_RS24765	COG0824	Thioesterase
C6N21_RS24770	COG0811	peptide transport
C6N21_RS24775	COG0848	biopolymer transport protein
C6N21_RS24780	COG3064	Membrane
C6N21_RS24790	COG2885	chlorophyll binding
C6N21_RS24795	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
C6N21_RS24840	COG3201	nicotinamide mononucleotide transporter
C6N21_RS24845	COG1230	cation diffusion facilitator family transporter
C6N21_RS24860	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C6N21_RS24870	COG2017	converts alpha-aldose to the beta-anomer
C6N21_RS24880	COG1085	galactose-1-phosphate uridylyltransferase
C6N21_RS24885	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C6N21_RS24890	COG1119	ATPase activity
C6N21_RS24895	COG2005	Transcriptional regulator
C6N21_RS24895	COG3585	molybdate ion transport
C6N21_RS24910	COG0725	ABC transporter, periplasmic molybdate-binding protein
C6N21_RS24915	COG4149	molybdate abc transporter
C6N21_RS24925	COG0561	phosphatase activity
C6N21_RS24935	COG0583	DNA-binding transcription factor activity
C6N21_RS24940	COG2828	Protein conserved in bacteria
C6N21_RS24945	COG0471	metal ion transport
C6N21_RS24950	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C6N21_RS24955	COG4677	pectinesterase activity
C6N21_RS24965	COG1881	PFAM PEBP family protein
C6N21_RS24970	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C6N21_RS24985	COG2226	methyltransferase
C6N21_RS24990	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C6N21_RS25000	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C6N21_RS25010	COG0521	Mo-molybdopterin cofactor biosynthetic process
C6N21_RS25020	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C6N21_RS25025	COG0314	molybdopterin synthase activity
C6N21_RS25030	COG0670	Belongs to the BI1 family
C6N21_RS25040	COG0670	Belongs to the BI1 family
C6N21_RS25045	COG0392	lysyltransferase activity
C6N21_RS25050	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C6N21_RS25055	COG3568	Endonuclease Exonuclease Phosphatase
C6N21_RS25065	COG0842	Transport permease protein
C6N21_RS25070	COG0842	Transport permease protein
C6N21_RS25075	COG1131	(ABC) transporter
C6N21_RS25085	COG1309	transcriptional regulator
C6N21_RS25090	COG0513	Belongs to the DEAD box helicase family
C6N21_RS25095	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
C6N21_RS25105	COG1199	ATP-dependent helicase activity
C6N21_RS25110	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C6N21_RS25115	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
C6N21_RS25125	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C6N21_RS25135	COG4774	siderophore transport
C6N21_RS25150	COG0668	transmembrane transport
C6N21_RS25155	COG1126	abc transporter atp-binding protein
C6N21_RS25160	COG0765	amino acid transport
C6N21_RS25165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6N21_RS25190	COG5006	permease, DMT superfamily
C6N21_RS25195	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
C6N21_RS25200	COG2194	sulfuric ester hydrolase activity
C6N21_RS25210	COG1321	iron dependent repressor
C6N21_RS25215	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C6N21_RS25220	COG1376	ErfK ybiS ycfS ynhG family protein
C6N21_RS25225	COG0488	(ABC) transporter
C6N21_RS25235	COG0561	phosphatase activity
C6N21_RS25240	COG1882	Formate acetyltransferase
C6N21_RS25245	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C6N21_RS25250	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C6N21_RS25255	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C6N21_RS25260	COG0303	'Molybdopterin
C6N21_RS25265	COG1446	asparaginase
C6N21_RS25290	COG2200	EAL domain
C6N21_RS25295	COG2199	diguanylate cyclase activity
C6N21_RS25310	COG2133	pyrroloquinoline quinone binding
C6N21_RS25320	COG1686	Belongs to the peptidase S11 family
C6N21_RS25325	COG1349	DNA-binding transcription factor activity
C6N21_RS25330	COG0671	phosphoesterase, PA-phosphatase related
C6N21_RS25335	COG2814	Major facilitator Superfamily
C6N21_RS25345	COG0561	phosphatase activity
C6N21_RS25350	COG0738	Major facilitator superfamily
C6N21_RS25355	COG3226	Transcriptional regulator
C6N21_RS25370	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C6N21_RS25380	COG0778	Nitroreductase
C6N21_RS25400	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C6N21_RS25405	COG3842	ATPase activity
C6N21_RS25410	COG1176	ABC-type spermidine putrescine transport system, permease component I
C6N21_RS25415	COG1177	transmembrane transport
C6N21_RS25430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6N21_RS25435	COG4160	amino acid transport
C6N21_RS25440	COG4215	(ABC) transporter
C6N21_RS25445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6N21_RS25450	COG1126	abc transporter atp-binding protein
C6N21_RS25465	COG3023	N-Acetylmuramoyl-L-alanine amidase
C6N21_RS25470	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C6N21_RS25475	COG0702	epimerase
C6N21_RS25480	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
C6N21_RS25485	COG0028	Belongs to the TPP enzyme family
C6N21_RS25490	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C6N21_RS25500	COG2431	L-lysine efflux transmembrane transporter activity
C6N21_RS25515	COG3593	DNA synthesis involved in DNA repair
C6N21_RS25520	COG2990	Protein conserved in bacteria
C6N21_RS25525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6N21_RS25535	COG1278	Cold shock
C6N21_RS25545	COG0542	response to heat
C6N21_RS25550	COG4372	Transposase
C6N21_RS25555	COG3436	PFAM IS66 Orf2 family protein
C6N21_RS25580	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C6N21_RS25585	COG4988	ABC transporter
C6N21_RS25590	COG0492	ferredoxin-NADP+ reductase activity
C6N21_RS25600	COG1522	sequence-specific DNA binding
C6N21_RS25605	COG1178	ABC-type Fe3 transport system permease component
C6N21_RS25605	COG1674	ftsk spoiiie
C6N21_RS25615	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C6N21_RS25625	COG0243	molybdopterin cofactor binding
C6N21_RS25630	COG0437	4 iron, 4 sulfur cluster binding
C6N21_RS25635	COG3302	dmso reductase anchor subunit
C6N21_RS25640	COG1335	isochorismatase
C6N21_RS25650	COG0531	amino acid
C6N21_RS25655	COG0583	DNA-binding transcription factor activity
C6N21_RS25660	COG2249	NAD(P)H dehydrogenase (quinone) activity
C6N21_RS25665	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C6N21_RS25670	COG1882	Formate acetyltransferase
C6N21_RS25675	COG2116	formate transmembrane transporter activity
C6N21_RS25680	COG1944	ATP diphosphatase activity
C6N21_RS25685	COG2323	membrane
C6N21_RS25700	COG0501	Belongs to the peptidase M48B family
C6N21_RS25710	COG0539	negative regulation of cytoplasmic translation
C6N21_RS25720	COG2333	competence protein COMEC
C6N21_RS25720	COG0658	competence protein
C6N21_RS25725	COG1132	(ABC) transporter
C6N21_RS25735	COG3214	Protein conserved in bacteria
C6N21_RS25750	COG3173	Aminoglycoside phosphotransferase
C6N21_RS25755	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C6N21_RS25760	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C6N21_RS25770	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
C6N21_RS25780	COG2989	Protein conserved in bacteria
C6N21_RS25790	COG3108	Peptidase M15
C6N21_RS25795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C6N21_RS25800	COG1448	Aminotransferase
C6N21_RS25820	COG0308	aminopeptidase N
C6N21_RS25830	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C6N21_RS25840	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C6N21_RS25845	COG0431	NADPH-dependent FMN reductase
C6N21_RS25850	COG3539	Fimbrial protein
C6N21_RS25865	COG3539	Fimbrial protein
C6N21_RS25870	COG3539	Fimbrial protein
C6N21_RS25875	COG3539	Fimbrial protein
C6N21_RS25880	COG3121	Chaperone
C6N21_RS25895	COG3217	Mosc domain protein beta barrel domain protein
C6N21_RS25895	COG0633	Ferredoxin
C6N21_RS25905	COG0488	(ABC) transporter
C6N21_RS25910	COG2995	paraquat-inducible protein a
C6N21_RS25915	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C6N21_RS25915	COG3008	intermembrane lipid transfer
C6N21_RS25920	COG3009	Protein conserved in bacteria
C6N21_RS25925	COG3130	regulation of translation
C6N21_RS25935	COG1067	ATP-dependent peptidase activity
C6N21_RS25965	COG1289	transmembrane transporter activity
C6N21_RS25970	COG3304	Inner membrane component domain
C6N21_RS25975	COG0210	DNA helicase
C6N21_RS25990	COG1832	CoA-binding protein
C6N21_RS26005	COG1254	Belongs to the acylphosphatase family
C6N21_RS26010	COG2920	part of a sulfur-relay system
C6N21_RS26015	COG0670	Belongs to the BI1 family
C6N21_RS26030	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6N21_RS26065	COG4197	protein conserved in bacteria, prophage-related
C6N21_RS26140	COG1403	HNH endonuclease
C6N21_RS26145	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C6N21_RS26190	COG3772	lysozyme
C6N21_RS26225	COG0740	serine-type endopeptidase activity
C6N21_RS26300	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6N21_RS26340	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6N21_RS26415	COG1484	DNA-dependent DNA replication
C6N21_RS26420	COG1846	Transcriptional regulator
C6N21_RS26445	COG1403	HNH endonuclease
C6N21_RS26450	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C6N21_RS26470	COG2207	Transcriptional regulator
C6N21_RS26530	COG3772	lysozyme
C6N21_RS26560	COG4220	transposase activity
C6N21_RS26665	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6N21_RS26705	COG1879	ABC-type sugar transport system periplasmic component
C6N21_RS26710	COG0745	RESPONSE REGULATOR receiver
C6N21_RS26715	COG3005	denitrification pathway
C6N21_RS26720	COG0243	molybdopterin cofactor binding
C6N21_RS26765	COG3729	General stress protein
C6N21_RS26770	COG2233	PERMEase
C6N21_RS26805	COG1309	transcriptional regulator
C6N21_RS26810	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C6N21_RS26810	COG0506	proline dehydrogenase activity
C6N21_RS26810	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C6N21_RS26825	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C6N21_RS26845	COG2822	iron ion transport
C6N21_RS26855	COG1702	phosphate starvation-inducible protein PhoH
C6N21_RS26885	COG3381	protein complex oligomerization
C6N21_RS26895	COG1462	curli production assembly transport component CsgG
C6N21_RS26910	COG2197	response regulator
C6N21_RS26945	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C6N21_RS26950	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C6N21_RS26975	COG2943	transferase activity, transferring hexosyl groups
C6N21_RS26980	COG5645	(Lipo)protein
C6N21_RS26995	COG1560	Kdo2-lipid A biosynthetic process
C6N21_RS27005	COG2353	YceI-like domain
C6N21_RS27010	COG3038	cytochrome b561
C6N21_RS27050	COG2999	glutathione oxidoreductase activity
C6N21_RS27060	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C6N21_RS27070	COG0673	inositol 2-dehydrogenase activity
C6N21_RS27075	COG0728	peptidoglycan biosynthetic process
C6N21_RS27080	COG3418	PFAM FlgN family protein
C6N21_RS27085	COG2747	anti-sigma28 factor FlgM
C6N21_RS27090	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
C6N21_RS27095	COG1815	bacterial-type flagellum-dependent cell motility
C6N21_RS27100	COG1558	bacterial-type flagellum-dependent cell motility
C6N21_RS27105	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C6N21_RS27110	COG1749	Flagellar hook protein flgE
C6N21_RS27115	COG4787	bacterial-type flagellum-dependent cell motility
C6N21_RS27120	COG4786	Flagellar basal body rod
C6N21_RS27135	COG1705	Flagellar rod assembly protein muramidase FlgJ
C6N21_RS27135	COG3951	Flagellar rod assembly protein muramidase FlgJ
C6N21_RS27140	COG1256	bacterial-type flagellum assembly
C6N21_RS27145	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C6N21_RS27150	COG1530	ribonuclease E activity
C6N21_RS27160	COG0564	pseudouridine synthase activity
C6N21_RS27165	COG0424	maF-like protein
C6N21_RS27170	COG1399	metal-binding, possibly nucleic acid-binding protein
C6N21_RS27190	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C6N21_RS27195	COG1028	Short-chain dehydrogenase reductase Sdr
C6N21_RS27205	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C6N21_RS27210	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C6N21_RS27215	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C6N21_RS27225	COG0470	DNA polymerase III
C6N21_RS27230	COG0084	hydrolase, TatD family'
C6N21_RS27235	COG1263	PTS System
C6N21_RS27235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6N21_RS27240	COG4773	Receptor
C6N21_RS27245	COG0537	adenosine 5'-monophosphoramidase activity
C6N21_RS27250	COG5633	Lipoprotein
C6N21_RS27255	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
C6N21_RS27275	COG1252	NADH dehydrogenase
C6N21_RS27285	COG3134	Outer membrane lipoprotein
C6N21_RS27290	COG1309	transcriptional regulator
C6N21_RS27300	COG1376	ErfK ybiS ycfS ynhG family protein
C6N21_RS27300	COG1388	LysM domain
C6N21_RS27305	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C6N21_RS27310	COG4763	Acyl-transferase
C6N21_RS27315	COG4591	ABC-type transport system involved in lipoprotein release permease component
C6N21_RS27325	COG4591	ABC-type transport system involved in lipoprotein release permease component
C6N21_RS27335	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C6N21_RS27340	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C6N21_RS27345	COG1177	transmembrane transport
C6N21_RS27360	COG0582	viral genome integration into host DNA
C6N21_RS27370	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6N21_RS27420	COG1846	Transcriptional regulator
C6N21_RS27440	COG4372	Transposase
C6N21_RS27445	COG3436	PFAM IS66 Orf2 family protein
C6N21_RS27480	COG3111	PFAM Bacterial OB fold (BOF) protein
C6N21_RS27490	COG1403	HNH endonuclease
C6N21_RS27495	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C6N21_RS27500	COG0484	heat shock protein binding
C6N21_RS27585	COG3772	lysozyme
C6N21_RS27685	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6N21_RS27715	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
C6N21_RS27720	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
C6N21_RS27725	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C6N21_RS27730	COG1999	signal sequence binding
C6N21_RS27735	COG1773	rubredoxin
C6N21_RS27740	COG1271	oxidase subunit
C6N21_RS27745	COG1294	oxidase, subunit
C6N21_RS27760	COG3206	protein involved in exopolysaccharide biosynthesis
C6N21_RS27760	COG0489	protein tyrosine kinase activity
C6N21_RS27765	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C6N21_RS27770	COG1596	polysaccharide export
C6N21_RS27775	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C6N21_RS27795	COG1278	Cold shock
C6N21_RS27800	COG1278	Cold shock
C6N21_RS27820	COG0348	domain, Protein
C6N21_RS27825	COG0784	Response regulator, receiver
C6N21_RS27825	COG2198	Histidine kinase
C6N21_RS27825	COG2205	protein histidine kinase activity
C6N21_RS27830	COG0582	viral genome integration into host DNA
C6N21_RS27995	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C6N21_RS28045	COG3436	PFAM IS66 Orf2 family protein
C6N21_RS28050	COG4372	Transposase
C6N21_RS28065	COG3772	lysozyme
C6N21_RS28090	COG4220	transposase activity
C6N21_RS28195	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6N21_RS28245	COG3842	ATPase activity
C6N21_RS28260	COG2850	peptidyl-arginine hydroxylation
C6N21_RS28265	COG2205	protein histidine kinase activity
C6N21_RS28275	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C6N21_RS28295	COG1187	pseudouridine synthase activity
C6N21_RS28300	COG0538	isocitrate dehydrogenase activity
C6N21_RS28310	COG5562	phage envelope protein
C6N21_RS28315	COG0789	Transcriptional regulator
C6N21_RS28320	COG2200	EAL domain
C6N21_RS28345	COG2200	EAL domain
C6N21_RS28405	COG2894	cell division
C6N21_RS28435	COG0179	Fumarylacetoacetate (FAA) hydrolase
C6N21_RS28450	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C6N21_RS28455	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C6N21_RS28475	COG2719	SpoVR family
C6N21_RS28485	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C6N21_RS28495	COG1619	proteins homologs of microcin C7 resistance protein MccF
C6N21_RS28510	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
C6N21_RS28535	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C6N21_RS28535	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
C6N21_RS28535	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6N21_RS28540	COG1461	Dihydroxyacetone kinase
C6N21_RS28545	COG2376	Dihydroxyacetone kinase
C6N21_RS28550	COG3284	Transcriptional regulator
C6N21_RS28555	COG3468	outer membrane autotransporter barrel domain protein
C6N21_RS28570	COG0012	GTP binding
C6N21_RS28585	COG0659	secondary active sulfate transmembrane transporter activity
C6N21_RS28595	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C6N21_RS28680	COG1585	Membrane protein implicated in regulation of membrane protease activity
C6N21_RS28695	COG3468	outer membrane autotransporter barrel domain protein
C6N21_RS28795	COG3436	PFAM IS66 Orf2 family protein
C6N21_RS28800	COG4372	Transposase
C6N21_RS28825	COG4372	Transposase
C6N21_RS28830	COG3436	PFAM IS66 Orf2 family protein
C6N21_RS28965	COG2274	protein secretion by the type I secretion system
C6N21_RS28990	COG0726	polysaccharide deacetylase
C6N21_RS28995	COG0297	glycogen (starch) synthase activity
C6N21_RS29000	COG2194	sulfuric ester hydrolase activity
C6N21_RS29005	COG1560	Kdo2-lipid A biosynthetic process
C6N21_RS29015	COG4372	Transposase
C6N21_RS29020	COG3436	PFAM IS66 Orf2 family protein