locus-tag	class	description
C7N18_RS00005	COG2186	Transcriptional regulator
C7N18_RS00010	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
C7N18_RS00015	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7N18_RS00020	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7N18_RS00025	COG3064	Membrane
C7N18_RS00030	COG1049	propionate catabolic process, 2-methylcitrate cycle
C7N18_RS00055	COG2132	Multicopper oxidase
C7N18_RS00060	COG4993	Dehydrogenase
C7N18_RS00065	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
C7N18_RS00070	COG0288	reversible hydration of carbon dioxide
C7N18_RS00075	COG1131	(ABC) transporter
C7N18_RS00080	COG0842	Transport permease protein
C7N18_RS00085	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7N18_RS00090	COG0726	polysaccharide deacetylase
C7N18_RS00100	COG5464	transposase or invertase
C7N18_RS00130	COG3539	Fimbrial protein
C7N18_RS00135	COG3539	Fimbrial protein
C7N18_RS00145	COG3121	Chaperone
C7N18_RS00155	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C7N18_RS00160	COG0617	tRNA 3'-terminal CCA addition
C7N18_RS00165	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C7N18_RS00170	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C7N18_RS00180	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C7N18_RS00185	COG1643	Atp-dependent helicase
C7N18_RS00190	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7N18_RS00195	COG4774	siderophore transport
C7N18_RS00200	COG1120	ATPase activity
C7N18_RS00205	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7N18_RS00210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7N18_RS00235	COG2860	membrane
C7N18_RS00240	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7N18_RS00255	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7N18_RS00260	COG3835	regulator
C7N18_RS00290	COG0024	Methionine aminopeptidase
C7N18_RS00315	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C7N18_RS00320	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C7N18_RS00325	COG0575	Belongs to the CDS family
C7N18_RS00330	COG0750	zinc metalloprotease
C7N18_RS00340	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
C7N18_RS00345	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C7N18_RS00370	COG0587	DNA-directed DNA polymerase activity
C7N18_RS00380	COG1982	Orn Lys Arg decarboxylase major
C7N18_RS00385	COG0346	lactoylglutathione lyase activity
C7N18_RS00390	COG0037	tRNA processing
C7N18_RS00395	COG4568	rho-dependent transcription termination
C7N18_RS00405	COG4681	YaeQ
C7N18_RS00410	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
C7N18_RS00415	COG3015	lipoprotein NlpE involved in copper resistance
C7N18_RS00420	COG0791	NLP P60 protein
C7N18_RS00430	COG1720	tRNA m6t6A37 methyltransferase activity
C7N18_RS00440	COG1464	Belongs to the NlpA lipoprotein family
C7N18_RS00445	COG2011	ABC-type metal ion transport system permease component
C7N18_RS00450	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C7N18_RS00455	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C7N18_RS00490	COG0656	L-ascorbic acid biosynthetic process
C7N18_RS00495	COG0583	DNA-binding transcription factor activity
C7N18_RS00505	COG2226	methyltransferase
C7N18_RS00510	COG1388	LysM domain
C7N18_RS00510	COG0741	lytic transglycosylase activity
C7N18_RS00520	COG2226	methyltransferase
C7N18_RS00530	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C7N18_RS00555	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7N18_RS00565	COG1960	acyl-CoA dehydrogenase activity
C7N18_RS00575	COG0121	glutamine amidotransferase
C7N18_RS00580	COG3034	peptidoglycan biosynthetic process
C7N18_RS00585	COG0791	NLP P60 protein
C7N18_RS00610	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C7N18_RS00615	COG0454	-acetyltransferase
C7N18_RS00620	COG1690	Belongs to the RtcB family
C7N18_RS00625	COG3547	Transposase (IS116 IS110 IS902 family)
C7N18_RS00635	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
C7N18_RS00640	COG2195	Cleaves the N-terminal amino acid of tripeptides
C7N18_RS00660	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C7N18_RS00680	COG0583	DNA-binding transcription factor activity
C7N18_RS00685	COG4221	oxidoreductase activity
C7N18_RS00700	COG0583	DNA-binding transcription factor activity
C7N18_RS00715	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C7N18_RS00720	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C7N18_RS00730	COG2080	2 iron, 2 sulfur cluster binding
C7N18_RS00740	COG3477	response to acidic pH
C7N18_RS00745	COG0727	PFAM Uncharacterised protein family (UPF0153)
C7N18_RS00750	COG3121	Chaperone
C7N18_RS00760	COG3188	usher protein
C7N18_RS00800	COG1902	pentaerythritol trinitrate reductase activity
C7N18_RS00805	COG1073	alpha beta
C7N18_RS00810	COG0583	DNA-binding transcription factor activity
C7N18_RS00820	COG0667	Aldo Keto reductase
C7N18_RS00825	COG0656	L-ascorbic acid biosynthetic process
C7N18_RS00830	COG1388	LysM domain
C7N18_RS00835	COG2207	Transcriptional regulator
C7N18_RS00835	COG3708	Transcriptional regulator
C7N18_RS00840	COG0656	L-ascorbic acid biosynthetic process
C7N18_RS00845	COG3059	membrane
C7N18_RS00855	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7N18_RS00860	COG2207	Transcriptional regulator
C7N18_RS00865	COG0247	lactate metabolic process
C7N18_RS00870	COG1139	Iron-sulfur cluster binding protein
C7N18_RS00875	COG1556	Lactate utilization protein
C7N18_RS00885	COG3468	outer membrane autotransporter barrel domain protein
C7N18_RS00910	COG2771	luxR family
C7N18_RS00910	COG2200	EAL domain
C7N18_RS00915	COG0582	viral genome integration into host DNA
C7N18_RS00940	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C7N18_RS00950	COG2771	luxR family
C7N18_RS00950	COG2200	EAL domain
C7N18_RS00955	COG0583	DNA-binding transcription factor activity
C7N18_RS00965	COG0666	response to abiotic stimulus
C7N18_RS00980	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C7N18_RS00985	COG1304	FMN binding
C7N18_RS00995	COG0549	Belongs to the carbamate kinase family
C7N18_RS01000	COG0402	S-adenosylhomocysteine deaminase activity
C7N18_RS01005	COG1064	alcohol dehydrogenase
C7N18_RS01020	COG1280	lysine exporter protein (LysE YggA)
C7N18_RS01030	COG3829	transcription factor binding
C7N18_RS01035	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C7N18_RS01040	COG0372	Belongs to the citrate synthase family
C7N18_RS01045	COG2079	MmgE PrpD family protein
C7N18_RS01050	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C7N18_RS01055	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C7N18_RS01060	COG0402	S-adenosylhomocysteine deaminase activity
C7N18_RS01065	COG0583	DNA-binding transcription factor activity
C7N18_RS01070	COG0288	reversible hydration of carbon dioxide
C7N18_RS01080	COG2807	transmembrane transport
C7N18_RS01085	COG0110	maltose O-acetyltransferase activity
C7N18_RS01090	COG2223	nitrite transmembrane transporter activity
C7N18_RS01095	COG3250	beta-galactosidase activity
C7N18_RS01100	COG1609	Transcriptional regulator
C7N18_RS01110	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
C7N18_RS01115	COG1414	Transcriptional regulator
C7N18_RS01130	COG0596	Alpha beta hydrolase
C7N18_RS01145	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C7N18_RS01150	COG2814	Major facilitator Superfamily
C7N18_RS01155	COG3122	Protein conserved in bacteria
C7N18_RS01175	COG3842	ATPase activity
C7N18_RS01185	COG1840	ABC-type Fe3 transport system, periplasmic component
C7N18_RS01190	COG2271	Major facilitator Superfamily
C7N18_RS01205	COG4521	taurine ABC transporter
C7N18_RS01215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C7N18_RS01220	COG2175	clavaminate synthase activity
C7N18_RS01225	COG0113	porphobilinogen synthase activity
C7N18_RS01230	COG3468	outer membrane autotransporter barrel domain protein
C7N18_RS01235	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7N18_RS01240	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7N18_RS01245	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
C7N18_RS01265	COG1181	Belongs to the D-alanine--D-alanine ligase family
C7N18_RS01275	COG1785	Belongs to the alkaline phosphatase family
C7N18_RS01285	COG3706	GGDEF domain
C7N18_RS01290	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7N18_RS01310	COG4126	flavin adenine dinucleotide binding
C7N18_RS01340	COG2814	Major facilitator Superfamily
C7N18_RS01345	COG0419	ATPase involved in DNA repair
C7N18_RS01350	COG0420	3'-5' exonuclease activity
C7N18_RS01355	COG0745	RESPONSE REGULATOR receiver
C7N18_RS01360	COG5002	protein histidine kinase activity
C7N18_RS01365	COG1114	Component of the transport system for branched-chain amino acids
C7N18_RS01370	COG1113	amino acid transport
C7N18_RS01400	COG1862	Preprotein translocase
C7N18_RS01405	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C7N18_RS01410	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C7N18_RS01415	COG1403	HNH endonuclease
C7N18_RS01420	COG3248	Nucleoside-binding outer membrane protein
C7N18_RS01425	COG4238	major outer membrane lipoprotein
C7N18_RS01435	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7N18_RS01435	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7N18_RS01450	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C7N18_RS01455	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C7N18_RS01465	COG0667	Aldo Keto reductase
C7N18_RS01475	COG0142	geranyltranstransferase activity
C7N18_RS01490	COG0693	protein deglycase activity
C7N18_RS01495	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C7N18_RS01505	COG2814	Major facilitator Superfamily
C7N18_RS01515	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C7N18_RS01520	COG1845	cytochrome c oxidase, subunit III
C7N18_RS01525	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C7N18_RS01530	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C7N18_RS01540	COG3056	Lipoprotein
C7N18_RS01545	COG0271	Belongs to the BolA IbaG family
C7N18_RS01565	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C7N18_RS01570	COG0776	regulation of translation
C7N18_RS01575	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C7N18_RS01580	COG1555	photosystem II stabilization
C7N18_RS01585	COG0824	Thioesterase
C7N18_RS01595	COG4533	DNA binding
C7N18_RS01605	COG1522	sequence-specific DNA binding
C7N18_RS01610	COG1132	(ABC) transporter
C7N18_RS01615	COG1132	(ABC) transporter
C7N18_RS01620	COG0347	Belongs to the P(II) protein family
C7N18_RS01625	COG0004	ammonium transporteR
C7N18_RS01630	COG1946	Acyl-CoA thioesterase
C7N18_RS01635	COG3126	Type III secretion system lipoprotein chaperone (YscW)
C7N18_RS01640	COG3695	enzyme binding
C7N18_RS01650	COG5507	3-demethylubiquinone-9 3-methyltransferase
C7N18_RS01655	COG4943	cyclic-guanylate-specific phosphodiesterase activity
C7N18_RS01665	COG0110	maltose O-acetyltransferase activity
C7N18_RS01680	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C7N18_RS01685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7N18_RS01690	COG1309	transcriptional regulator
C7N18_RS01695	COG1196	nuclear chromosome segregation
C7N18_RS01695	COG3264	Mechanosensitive ion channel
C7N18_RS01705	COG3923	Primosomal replication protein n
C7N18_RS01710	COG2832	Protein of unknown function (DUF454)
C7N18_RS01720	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C7N18_RS01755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7N18_RS01760	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C7N18_RS01760	COG4651	solute:proton antiporter activity
C7N18_RS01765	COG2223	nitrite transmembrane transporter activity
C7N18_RS01770	COG0737	Belongs to the 5'-nucleotidase family
C7N18_RS01780	COG3735	TraB family
C7N18_RS01795	COG2217	Heavy metal translocating P-type atpase
C7N18_RS01800	COG2066	Belongs to the glutaminase family
C7N18_RS01805	COG0531	amino acid
C7N18_RS01835	COG0789	Transcriptional regulator
C7N18_RS01865	COG1585	Membrane protein implicated in regulation of membrane protease activity
C7N18_RS01870	COG0330	HflC and HflK could
C7N18_RS01875	COG4619	ABC transporter
C7N18_RS01880	COG0390	transport system, permease component
C7N18_RS01885	COG3118	belongs to the thioredoxin family
C7N18_RS01890	COG0300	oxidoreductase activity
C7N18_RS01895	COG2755	lipolytic protein G-D-S-L family
C7N18_RS01900	COG4181	ATPase activity
C7N18_RS01905	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
C7N18_RS01915	COG0583	DNA-binding transcription factor activity
C7N18_RS01925	COG1414	Transcriptional regulator
C7N18_RS01930	COG3960	tartronate-semialdehyde synthase activity
C7N18_RS01935	COG3622	Belongs to the hyi family
C7N18_RS01940	COG2084	Dehydrogenase
C7N18_RS01945	COG1953	Uracil, thiamine, allantoin
C7N18_RS01955	COG2233	PERMEase
C7N18_RS01960	COG1929	Belongs to the glycerate kinase type-1 family
C7N18_RS01965	COG3257	ureidoglycine aminohydrolase activity
C7N18_RS01970	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7N18_RS01975	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
C7N18_RS01980	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C7N18_RS01985	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C7N18_RS01995	COG0549	Belongs to the carbamate kinase family
C7N18_RS02000	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C7N18_RS02005	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C7N18_RS02015	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C7N18_RS02025	COG1988	membrane-bound metal-dependent
C7N18_RS02030	COG2501	S4 domain
C7N18_RS02040	COG3539	Fimbrial protein
C7N18_RS02045	COG3121	Chaperone
C7N18_RS02050	COG3188	usher protein
C7N18_RS02055	COG3539	Fimbrial protein
C7N18_RS02060	COG3539	Fimbrial protein
C7N18_RS02065	COG2197	response regulator
C7N18_RS02075	COG0582	viral genome integration into host DNA
C7N18_RS02090	COG3772	lysozyme
C7N18_RS02110	COG4220	transposase activity
C7N18_RS02130	COG1030	water channel activity
C7N18_RS02180	COG1196	nuclear chromosome segregation
C7N18_RS02215	COG5301	cellulose 1,4-beta-cellobiosidase activity
C7N18_RS02220	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C7N18_RS02230	COG0500	methyltransferase
C7N18_RS02245	COG4571	Outer membrane protease
C7N18_RS02260	COG4783	chaperone-mediated protein folding
C7N18_RS02265	COG1215	transferase activity, transferring glycosyl groups
C7N18_RS02270	COG5002	protein histidine kinase activity
C7N18_RS02275	COG0745	RESPONSE REGULATOR receiver
C7N18_RS02280	COG1538	Outer membrane efflux protein
C7N18_RS02285	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7N18_RS02290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7N18_RS02295	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C7N18_RS02300	COG1113	amino acid transport
C7N18_RS02305	COG0668	transmembrane transport
C7N18_RS02310	COG0778	Nitroreductase
C7N18_RS02315	COG2315	Protein conserved in bacteria
C7N18_RS02350	COG2977	Belongs to the P-Pant transferase superfamily
C7N18_RS02355	COG4771	TonB-dependent receptor
C7N18_RS02360	COG2382	esterase
C7N18_RS02365	COG3251	PFAM MbtH domain protein
C7N18_RS02370	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
C7N18_RS02370	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7N18_RS02375	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
C7N18_RS02380	COG1120	ATPase activity
C7N18_RS02385	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7N18_RS02390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7N18_RS02400	COG4592	Periplasmic binding protein
C7N18_RS02405	COG1169	isochorismate synthase
C7N18_RS02410	COG1021	2,3-dihydroxybenzoate-AMP ligase
C7N18_RS02415	COG1535	isochorismatase
C7N18_RS02415	COG3433	isochorismatase activity
C7N18_RS02420	COG1028	Short-chain dehydrogenase reductase Sdr
C7N18_RS02425	COG2050	protein possibly involved in aromatic compounds catabolism
C7N18_RS02435	COG1966	Carbon starvation protein
C7N18_RS02440	COG2879	small protein
C7N18_RS02445	COG0371	Dehydrogenase
C7N18_RS02450	COG0436	Aminotransferase
C7N18_RS02455	COG1475	DNA binding
C7N18_RS02460	COG3969	phosphoadenosine phosphosulfate
C7N18_RS02465	COG0583	DNA-binding transcription factor activity
C7N18_RS02470	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C7N18_RS02475	COG0450	alkyl hydroperoxide reductase
C7N18_RS02480	COG3634	alkyl hydroperoxide reductase activity
C7N18_RS02485	COG0589	response to stress
C7N18_RS02490	COG1063	alcohol dehydrogenase
C7N18_RS02495	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C7N18_RS02500	COG3719	Belongs to the RNase T2 family
C7N18_RS02505	COG0471	metal ion transport
C7N18_RS02520	COG3051	citrate lyase alpha subunit
C7N18_RS02525	COG2301	Belongs to the HpcH HpaI aldolase family
C7N18_RS02535	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
C7N18_RS02540	COG3290	protein histidine kinase activity
C7N18_RS02545	COG4565	transcriptional regulatory protein
C7N18_RS02550	COG3069	C4-dicarboxylate transmembrane transporter activity
C7N18_RS02570	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7N18_RS02575	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C7N18_RS02585	COG0583	DNA-binding transcription factor activity
C7N18_RS02600	COG1686	Belongs to the peptidase S11 family
C7N18_RS02605	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C7N18_RS02610	COG0772	Belongs to the SEDS family
C7N18_RS02615	COG0768	penicillin binding
C7N18_RS02625	COG0799	negative regulation of ribosome biogenesis
C7N18_RS02630	COG0406	alpha-ribazole phosphatase activity
C7N18_RS02640	COG1466	dna polymerase III delta subunit
C7N18_RS02655	COG2888	peptidyl-tyrosine sulfation
C7N18_RS02660	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C7N18_RS02670	COG2214	Heat shock protein DnaJ domain protein
C7N18_RS02675	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C7N18_RS02685	COG2214	Heat shock protein DnaJ domain protein
C7N18_RS02690	COG0443	Heat shock 70 kDa protein
C7N18_RS02700	COG1126	abc transporter atp-binding protein
C7N18_RS02705	COG0765	amino acid transport
C7N18_RS02710	COG0765	amino acid transport
C7N18_RS02715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7N18_RS02720	COG0815	Transfers the fatty acyl group on membrane lipoproteins
C7N18_RS02725	COG4535	Mg2 and Co2 transporter CorC
C7N18_RS02735	COG1702	phosphate starvation-inducible protein PhoH
C7N18_RS02745	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C7N18_RS02785	COG0367	asparagine synthase
C7N18_RS02790	COG0647	UMP catabolic process
C7N18_RS02795	COG1846	Transcriptional regulator
C7N18_RS02795	COG1940	carbohydrate kinase activity
C7N18_RS02800	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C7N18_RS02810	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7N18_RS02810	COG1263	PTS System
C7N18_RS02810	COG2190	(PTS) system
C7N18_RS02835	COG0735	belongs to the Fur family
C7N18_RS02845	COG0716	FMN binding
C7N18_RS02855	COG0596	Alpha beta hydrolase
C7N18_RS02860	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
C7N18_RS02865	COG0033	Phosphoglucomutase
C7N18_RS02870	COG0745	RESPONSE REGULATOR receiver
C7N18_RS02905	COG3272	Protein of unknown function (DUF1722)
C7N18_RS02910	COG0415	Belongs to the DNA photolyase family
C7N18_RS02920	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C7N18_RS02925	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C7N18_RS02930	COG1984	allophanate hydrolase subunit 2
C7N18_RS02945	COG3180	Ammonia monooxygenase
C7N18_RS02950	COG3539	Fimbrial protein
C7N18_RS02955	COG3121	Chaperone
C7N18_RS02960	COG3188	usher protein
C7N18_RS02965	COG3539	Fimbrial protein
C7N18_RS02970	COG0372	Belongs to the citrate synthase family
C7N18_RS02980	COG2009	succinate dehydrogenase
C7N18_RS02985	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
C7N18_RS02990	COG1053	succinate dehydrogenase
C7N18_RS02995	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C7N18_RS03000	COG0567	Dehydrogenase, E1 component
C7N18_RS03005	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7N18_RS03015	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C7N18_RS03030	COG0583	DNA-binding transcription factor activity
C7N18_RS03035	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
C7N18_RS03040	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C7N18_RS03040	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C7N18_RS03045	COG1301	dicarboxylic acid transport
C7N18_RS03065	COG4865	methylaspartate mutase activity
C7N18_RS03075	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C7N18_RS03090	COG1271	oxidase subunit
C7N18_RS03095	COG1294	oxidase, subunit
C7N18_RS03100	COG4890	Cyd operon protein YbgT
C7N18_RS03105	COG3790	cyd operon protein YbgE
C7N18_RS03110	COG0824	Thioesterase
C7N18_RS03115	COG0811	peptide transport
C7N18_RS03120	COG0848	biopolymer transport protein
C7N18_RS03125	COG3064	Membrane
C7N18_RS03135	COG2885	chlorophyll binding
C7N18_RS03140	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
C7N18_RS03185	COG3201	nicotinamide mononucleotide transporter
C7N18_RS03190	COG1230	cation diffusion facilitator family transporter
C7N18_RS03200	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C7N18_RS03210	COG2017	converts alpha-aldose to the beta-anomer
C7N18_RS03220	COG1085	galactose-1-phosphate uridylyltransferase
C7N18_RS03225	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C7N18_RS03230	COG1119	ATPase activity
C7N18_RS03235	COG3585	molybdate ion transport
C7N18_RS03235	COG2005	Transcriptional regulator
C7N18_RS03245	COG0725	ABC transporter, periplasmic molybdate-binding protein
C7N18_RS03250	COG4149	molybdate abc transporter
C7N18_RS03260	COG0561	phosphatase activity
C7N18_RS03270	COG0583	DNA-binding transcription factor activity
C7N18_RS03300	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C7N18_RS03305	COG4677	pectinesterase activity
C7N18_RS03310	COG0582	viral genome integration into host DNA
C7N18_RS03370	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C7N18_RS03410	COG3547	Transposase (IS116 IS110 IS902 family)
C7N18_RS03460	COG4220	transposase activity
C7N18_RS03510	COG5301	cellulose 1,4-beta-cellobiosidase activity
C7N18_RS03565	COG1881	PFAM PEBP family protein
C7N18_RS03570	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C7N18_RS03585	COG2226	methyltransferase
C7N18_RS03590	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C7N18_RS03600	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C7N18_RS03610	COG0521	Mo-molybdopterin cofactor biosynthetic process
C7N18_RS03620	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C7N18_RS03625	COG0314	molybdopterin synthase activity
C7N18_RS03630	COG0670	Belongs to the BI1 family
C7N18_RS03635	COG0670	Belongs to the BI1 family
C7N18_RS03640	COG0392	lysyltransferase activity
C7N18_RS03645	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7N18_RS03650	COG3568	Endonuclease Exonuclease Phosphatase
C7N18_RS03660	COG0842	Transport permease protein
C7N18_RS03665	COG0842	Transport permease protein
C7N18_RS03670	COG1131	(ABC) transporter
C7N18_RS03680	COG1309	transcriptional regulator
C7N18_RS03685	COG0513	Belongs to the DEAD box helicase family
C7N18_RS03695	COG1199	ATP-dependent helicase activity
C7N18_RS03700	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C7N18_RS03705	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
C7N18_RS03715	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C7N18_RS03725	COG4774	siderophore transport
C7N18_RS03740	COG0668	transmembrane transport
C7N18_RS03745	COG1126	abc transporter atp-binding protein
C7N18_RS03750	COG0765	amino acid transport
C7N18_RS03755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7N18_RS03765	COG5006	permease, DMT superfamily
C7N18_RS03775	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
C7N18_RS03780	COG2194	sulfuric ester hydrolase activity
C7N18_RS03790	COG1321	iron dependent repressor
C7N18_RS03795	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C7N18_RS03800	COG1376	ErfK ybiS ycfS ynhG family protein
C7N18_RS03805	COG0488	(ABC) transporter
C7N18_RS03815	COG0561	phosphatase activity
C7N18_RS03820	COG1882	Formate acetyltransferase
C7N18_RS03825	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C7N18_RS03830	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C7N18_RS03835	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C7N18_RS03840	COG0303	'Molybdopterin
C7N18_RS03845	COG1446	asparaginase
C7N18_RS03855	COG0747	negative chemotaxis
C7N18_RS03870	COG2200	EAL domain
C7N18_RS03875	COG2199	diguanylate cyclase activity
C7N18_RS03890	COG2133	pyrroloquinoline quinone binding
C7N18_RS03895	COG0625	glutathione transferase activity
C7N18_RS03900	COG1686	Belongs to the peptidase S11 family
C7N18_RS03905	COG1349	DNA-binding transcription factor activity
C7N18_RS03910	COG0671	phosphoesterase, PA-phosphatase related
C7N18_RS03915	COG2814	Major facilitator Superfamily
C7N18_RS03925	COG0561	phosphatase activity
C7N18_RS03930	COG0738	Major facilitator superfamily
C7N18_RS03935	COG3226	Transcriptional regulator
C7N18_RS03955	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C7N18_RS03965	COG0778	Nitroreductase
C7N18_RS03985	COG3842	ATPase activity
C7N18_RS03995	COG1177	transmembrane transport
C7N18_RS04025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7N18_RS04030	COG4160	amino acid transport
C7N18_RS04035	COG4215	(ABC) transporter
C7N18_RS04040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7N18_RS04045	COG1126	abc transporter atp-binding protein
C7N18_RS04075	COG3023	N-Acetylmuramoyl-L-alanine amidase
C7N18_RS04080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7N18_RS04085	COG0702	epimerase
C7N18_RS04090	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
C7N18_RS04095	COG0028	Belongs to the TPP enzyme family
C7N18_RS04100	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C7N18_RS04110	COG2431	L-lysine efflux transmembrane transporter activity
C7N18_RS04120	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C7N18_RS04125	COG3593	DNA synthesis involved in DNA repair
C7N18_RS04130	COG2990	Protein conserved in bacteria
C7N18_RS04135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7N18_RS04140	COG1136	(ABC) transporter
C7N18_RS04140	COG0577	efflux transmembrane transporter activity
C7N18_RS04145	COG1278	Cold shock
C7N18_RS04155	COG0542	response to heat
C7N18_RS04180	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C7N18_RS04185	COG4988	ABC transporter
C7N18_RS04190	COG0492	ferredoxin-NADP+ reductase activity
C7N18_RS04195	COG1522	sequence-specific DNA binding
C7N18_RS04210	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C7N18_RS04220	COG0243	molybdopterin cofactor binding
C7N18_RS04225	COG0437	4 iron, 4 sulfur cluster binding
C7N18_RS04230	COG3302	dmso reductase anchor subunit
C7N18_RS04235	COG1335	isochorismatase
C7N18_RS04245	COG0531	amino acid
C7N18_RS04255	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C7N18_RS04260	COG1882	Formate acetyltransferase
C7N18_RS04265	COG2116	formate transmembrane transporter activity
C7N18_RS04270	COG1944	ATP diphosphatase activity
C7N18_RS04275	COG2323	membrane
C7N18_RS04290	COG0501	Belongs to the peptidase M48B family
C7N18_RS04300	COG0539	negative regulation of cytoplasmic translation
C7N18_RS04310	COG0658	competence protein
C7N18_RS04310	COG2333	competence protein COMEC
C7N18_RS04315	COG1132	(ABC) transporter
C7N18_RS04325	COG3214	Protein conserved in bacteria
C7N18_RS04340	COG3173	Aminoglycoside phosphotransferase
C7N18_RS04345	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C7N18_RS04350	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C7N18_RS04360	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
C7N18_RS04370	COG2989	Protein conserved in bacteria
C7N18_RS04375	COG3108	Peptidase M15
C7N18_RS04380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7N18_RS04385	COG1448	Aminotransferase
C7N18_RS04405	COG0308	aminopeptidase N
C7N18_RS04410	COG1116	anion transmembrane transporter activity
C7N18_RS04415	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C7N18_RS04425	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C7N18_RS04430	COG0431	NADPH-dependent FMN reductase
C7N18_RS04435	COG3539	Fimbrial protein
C7N18_RS04440	COG3121	Chaperone
C7N18_RS04450	COG3539	Fimbrial protein
C7N18_RS04455	COG3539	Fimbrial protein
C7N18_RS04460	COG3539	Fimbrial protein
C7N18_RS04465	COG3121	Chaperone
C7N18_RS04480	COG3217	Mosc domain protein beta barrel domain protein
C7N18_RS04480	COG0633	Ferredoxin
C7N18_RS04490	COG0488	(ABC) transporter
C7N18_RS04495	COG2995	paraquat-inducible protein a
C7N18_RS04500	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C7N18_RS04500	COG3008	intermembrane lipid transfer
C7N18_RS04505	COG3009	Protein conserved in bacteria
C7N18_RS04510	COG3130	regulation of translation
C7N18_RS04520	COG1067	ATP-dependent peptidase activity
C7N18_RS04540	COG3070	regulator of competence-specific genes
C7N18_RS04545	COG1289	transmembrane transporter activity
C7N18_RS04550	COG3304	Inner membrane component domain
C7N18_RS04555	COG0210	DNA helicase
C7N18_RS04570	COG1832	CoA-binding protein
C7N18_RS04585	COG1254	Belongs to the acylphosphatase family
C7N18_RS04590	COG2920	part of a sulfur-relay system
C7N18_RS04595	COG0670	Belongs to the BI1 family
C7N18_RS04615	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C7N18_RS04645	COG1484	DNA-dependent DNA replication
C7N18_RS04650	COG1846	Transcriptional regulator
C7N18_RS04685	COG1403	HNH endonuclease
C7N18_RS04690	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C7N18_RS04710	COG2207	Transcriptional regulator
C7N18_RS04755	COG3772	lysozyme
C7N18_RS04790	COG4220	transposase activity
C7N18_RS04890	COG2032	superoxide dismutase activity
C7N18_RS04930	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
C7N18_RS04935	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
C7N18_RS04940	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
C7N18_RS04945	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C7N18_RS04950	COG1999	signal sequence binding
C7N18_RS04955	COG1773	rubredoxin
C7N18_RS04960	COG1271	oxidase subunit
C7N18_RS04965	COG1294	oxidase, subunit
C7N18_RS04980	COG0489	protein tyrosine kinase activity
C7N18_RS04980	COG3206	protein involved in exopolysaccharide biosynthesis
C7N18_RS04985	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7N18_RS04995	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C7N18_RS05015	COG1278	Cold shock
C7N18_RS05020	COG1278	Cold shock
C7N18_RS05040	COG0348	domain, Protein
C7N18_RS05045	COG2198	Histidine kinase
C7N18_RS05045	COG2205	protein histidine kinase activity
C7N18_RS05045	COG0784	Response regulator, receiver
C7N18_RS05050	COG1879	ABC-type sugar transport system periplasmic component
C7N18_RS05055	COG0745	RESPONSE REGULATOR receiver
C7N18_RS05060	COG3005	denitrification pathway
C7N18_RS05065	COG0243	molybdopterin cofactor binding
C7N18_RS05105	COG3729	General stress protein
C7N18_RS05110	COG2233	PERMEase
C7N18_RS05145	COG1309	transcriptional regulator
C7N18_RS05150	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C7N18_RS05150	COG0506	proline dehydrogenase activity
C7N18_RS05150	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C7N18_RS05160	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7N18_RS05175	COG2822	iron ion transport
C7N18_RS05185	COG1702	phosphate starvation-inducible protein PhoH
C7N18_RS05190	COG3658	cytochrome
C7N18_RS05205	COG0457	Tetratricopeptide repeat
C7N18_RS05220	COG3710	Transcriptional regulator
C7N18_RS05225	COG1028	Short-chain dehydrogenase reductase Sdr
C7N18_RS05230	COG3121	Chaperone
C7N18_RS05270	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C7N18_RS05275	COG2194	sulfuric ester hydrolase activity
C7N18_RS05285	COG0829	nickel cation binding
C7N18_RS05330	COG0254	rRNA binding
C7N18_RS05375	COG3436	PFAM IS66 Orf2 family protein
C7N18_RS05380	COG4372	Transposase
C7N18_RS05415	COG1358	cellular component organization or biogenesis
C7N18_RS05580	COG2831	hemolysin activation secretion protein
C7N18_RS05585	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
C7N18_RS05590	COG3969	phosphoadenosine phosphosulfate
C7N18_RS05595	COG1475	DNA binding
C7N18_RS05685	COG3468	outer membrane autotransporter barrel domain protein
C7N18_RS05720	COG2003	Belongs to the UPF0758 family
C7N18_RS05770	COG3381	protein complex oligomerization
C7N18_RS05780	COG1462	curli production assembly transport component CsgG
C7N18_RS05795	COG2197	response regulator
C7N18_RS05820	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C7N18_RS05825	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7N18_RS05840	COG2943	transferase activity, transferring hexosyl groups
C7N18_RS05845	COG5645	(Lipo)protein
C7N18_RS05860	COG1560	Kdo2-lipid A biosynthetic process
C7N18_RS05870	COG2353	YceI-like domain
C7N18_RS05875	COG3038	cytochrome b561
C7N18_RS05910	COG2999	glutathione oxidoreductase activity
C7N18_RS05920	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7N18_RS05930	COG0673	inositol 2-dehydrogenase activity
C7N18_RS05935	COG0728	peptidoglycan biosynthetic process
C7N18_RS05940	COG3418	PFAM FlgN family protein
C7N18_RS05945	COG2747	anti-sigma28 factor FlgM
C7N18_RS05950	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
C7N18_RS05955	COG1815	bacterial-type flagellum-dependent cell motility
C7N18_RS05960	COG1558	bacterial-type flagellum-dependent cell motility
C7N18_RS05965	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C7N18_RS05970	COG1749	Flagellar hook protein flgE
C7N18_RS05975	COG4787	bacterial-type flagellum-dependent cell motility
C7N18_RS05980	COG4786	Flagellar basal body rod
C7N18_RS05995	COG3951	Flagellar rod assembly protein muramidase FlgJ
C7N18_RS05995	COG1705	Flagellar rod assembly protein muramidase FlgJ
C7N18_RS06000	COG1256	bacterial-type flagellum assembly
C7N18_RS06005	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C7N18_RS06010	COG1530	ribonuclease E activity
C7N18_RS06020	COG0564	pseudouridine synthase activity
C7N18_RS06025	COG0424	maF-like protein
C7N18_RS06030	COG1399	metal-binding, possibly nucleic acid-binding protein
C7N18_RS06050	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C7N18_RS06055	COG1028	Short-chain dehydrogenase reductase Sdr
C7N18_RS06065	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C7N18_RS06070	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7N18_RS06075	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C7N18_RS06085	COG0470	DNA polymerase III
C7N18_RS06095	COG1263	PTS System
C7N18_RS06095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7N18_RS06100	COG4773	Receptor
C7N18_RS06105	COG0537	adenosine 5'-monophosphoramidase activity
C7N18_RS06110	COG5633	Lipoprotein
C7N18_RS06115	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
C7N18_RS06135	COG1252	NADH dehydrogenase
C7N18_RS06140	COG3134	Outer membrane lipoprotein
C7N18_RS06145	COG1309	transcriptional regulator
C7N18_RS06155	COG1388	LysM domain
C7N18_RS06155	COG1376	ErfK ybiS ycfS ynhG family protein
C7N18_RS06160	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C7N18_RS06165	COG4763	Acyl-transferase
C7N18_RS06170	COG4591	ABC-type transport system involved in lipoprotein release permease component
C7N18_RS06175	COG1136	(ABC) transporter
C7N18_RS06180	COG4591	ABC-type transport system involved in lipoprotein release permease component
C7N18_RS06190	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C7N18_RS06195	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C7N18_RS06200	COG1177	transmembrane transport
C7N18_RS06205	COG0582	viral genome integration into host DNA
C7N18_RS06215	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C7N18_RS06235	COG1403	HNH endonuclease
C7N18_RS06240	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C7N18_RS06245	COG0484	heat shock protein binding
C7N18_RS06285	COG3772	lysozyme
C7N18_RS06440	COG5301	cellulose 1,4-beta-cellobiosidase activity
C7N18_RS06525	COG3842	ATPase activity
C7N18_RS06535	COG2850	peptidyl-arginine hydroxylation
C7N18_RS06635	COG4220	transposase activity
C7N18_RS06645	COG2205	protein histidine kinase activity
C7N18_RS06655	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C7N18_RS06675	COG1187	pseudouridine synthase activity
C7N18_RS06680	COG0538	isocitrate dehydrogenase activity
C7N18_RS06695	COG5562	phage envelope protein
C7N18_RS06700	COG0789	Transcriptional regulator
C7N18_RS06705	COG2200	EAL domain
C7N18_RS06730	COG2200	EAL domain
C7N18_RS06780	COG2894	cell division
C7N18_RS06805	COG0179	Fumarylacetoacetate (FAA) hydrolase
C7N18_RS06820	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C7N18_RS06825	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C7N18_RS06830	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C7N18_RS06845	COG2719	SpoVR family
C7N18_RS06855	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C7N18_RS06890	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
C7N18_RS06905	COG0157	Belongs to the NadC ModD family
C7N18_RS06910	COG0500	methyltransferase
C7N18_RS06915	COG1120	ATPase activity
C7N18_RS06920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7N18_RS06925	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7N18_RS06940	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
C7N18_RS06940	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C7N18_RS06940	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7N18_RS06945	COG1461	Dihydroxyacetone kinase
C7N18_RS06950	COG2376	Dihydroxyacetone kinase
C7N18_RS06955	COG3284	Transcriptional regulator
C7N18_RS06980	COG0012	GTP binding
C7N18_RS06995	COG0659	secondary active sulfate transmembrane transporter activity
C7N18_RS07000	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C7N18_RS07025	COG2890	protein-(glutamine-N5) methyltransferase activity
C7N18_RS07030	COG3094	Invasion gene expression up-regulator, SirB
C7N18_RS07035	COG2912	Transglutaminase-like superfamily
C7N18_RS07055	COG0387	Pfam Sodium calcium exchanger
C7N18_RS07060	COG4572	Cation transport regulator
C7N18_RS07065	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
C7N18_RS07070	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
C7N18_RS07075	COG4932	domain protein
C7N18_RS07080	COG2197	response regulator
C7N18_RS07085	COG3850	Histidine kinase
C7N18_RS07090	COG2223	nitrite transmembrane transporter activity
C7N18_RS07095	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C7N18_RS07100	COG1140	nitrate reductase beta subunit
C7N18_RS07105	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C7N18_RS07110	COG2181	nitrate reductase activity
C7N18_RS07130	COG0788	formyltetrahydrofolate deformylase activity
C7N18_RS07140	COG1752	Esterase of the alpha-beta hydrolase superfamily
C7N18_RS07145	COG0745	RESPONSE REGULATOR receiver
C7N18_RS07150	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C7N18_RS07160	COG1435	thymidine kinase activity
C7N18_RS07165	COG1012	belongs to the aldehyde dehydrogenase family
C7N18_RS07165	COG1454	alcohol dehydrogenase
C7N18_RS07170	COG2095	MarC family integral membrane protein
C7N18_RS07175	COG4166	transmembrane transport
C7N18_RS07180	COG0601	transmembrane transport
C7N18_RS07185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7N18_RS07190	COG0444	Belongs to the ABC transporter superfamily
C7N18_RS07195	COG4608	Belongs to the ABC transporter superfamily
C7N18_RS07215	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C7N18_RS07220	COG2350	Protein conserved in bacteria
C7N18_RS07225	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
C7N18_RS07230	COG1607	acyl-coa hydrolase
C7N18_RS07250	COG3047	cAMP biosynthetic process
C7N18_RS07255	COG0582	viral genome integration into host DNA
C7N18_RS07310	COG1396	sequence-specific DNA binding
C7N18_RS07335	COG1846	Transcriptional regulator
C7N18_RS07370	COG1403	HNH endonuclease
C7N18_RS07375	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C7N18_RS07400	COG3547	Transposase (IS116 IS110 IS902 family)
C7N18_RS07560	COG0582	viral genome integration into host DNA
C7N18_RS07610	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C7N18_RS07645	COG1484	DNA-dependent DNA replication
C7N18_RS07650	COG0305	Participates in initiation and elongation during chromosome replication
C7N18_RS07660	COG1403	HNH endonuclease
C7N18_RS07730	COG3772	lysozyme
C7N18_RS07760	COG0582	viral genome integration into host DNA
C7N18_RS07825	COG0740	serine-type endopeptidase activity
C7N18_RS07850	COG0740	serine-type endopeptidase activity
C7N18_RS07925	COG5301	cellulose 1,4-beta-cellobiosidase activity
C7N18_RS07965	COG3685	Protein conserved in bacteria
C7N18_RS07970	COG3685	Protein conserved in bacteria
C7N18_RS07975	COG3729	General stress protein
C7N18_RS07980	COG0159	tryptophan synthase activity
C7N18_RS07990	COG0134	indole-3-glycerol-phosphate synthase activity
C7N18_RS07990	COG0135	phosphoribosylanthranilate isomerase activity
C7N18_RS07995	COG0512	Glutamine amidotransferase of anthranilate synthase
C7N18_RS07995	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C7N18_RS08000	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C7N18_RS08010	COG0613	PHP domain protein
C7N18_RS08015	COG0009	L-threonylcarbamoyladenylate synthase
C7N18_RS08020	COG4907	membrane protein (DUF2207)
C7N18_RS08025	COG1187	pseudouridine synthase activity
C7N18_RS08030	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
C7N18_RS08035	COG1028	Short-chain dehydrogenase reductase Sdr
C7N18_RS08040	COG0616	signal peptide processing
C7N18_RS08055	COG0583	DNA-binding transcription factor activity
C7N18_RS08075	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C7N18_RS08085	COG0671	phosphoesterase, PA-phosphatase related
C7N18_RS08090	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
C7N18_RS08095	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
C7N18_RS08105	COG0023	Translation Initiation Factor
C7N18_RS08115	COG1349	DNA-binding transcription factor activity
C7N18_RS08125	COG5001	Diguanylate cyclase
C7N18_RS08140	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C7N18_RS08140	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C7N18_RS08145	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C7N18_RS08155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7N18_RS08175	COG4172	Belongs to the ABC transporter superfamily
C7N18_RS08180	COG4172	Belongs to the ABC transporter superfamily
C7N18_RS08185	COG4171	peptide transport system, permease
C7N18_RS08190	COG4168	peptide transport system, permease
C7N18_RS08195	COG4166	transmembrane transport
C7N18_RS08205	COG0531	amino acid
C7N18_RS08215	COG0174	glutamine synthetase
C7N18_RS08225	COG1917	Cupin 2, conserved barrel domain protein
C7N18_RS08225	COG1396	sequence-specific DNA binding
C7N18_RS08230	COG1012	belongs to the aldehyde dehydrogenase family
C7N18_RS08235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7N18_RS08240	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C7N18_RS08245	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C7N18_RS08250	COG1842	Phage shock protein A
C7N18_RS08260	COG1983	PspC domain protein
C7N18_RS08270	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7N18_RS08275	COG0366	Alpha amylase catalytic
C7N18_RS08280	COG1653	transport
C7N18_RS08285	COG1175	transmembrane transport
C7N18_RS08290	COG0395	ABC-type sugar transport system, permease component
C7N18_RS08295	COG1063	alcohol dehydrogenase
C7N18_RS08300	COG1082	Xylose isomerase domain protein TIM barrel
C7N18_RS08305	COG0673	inositol 2-dehydrogenase activity
C7N18_RS08310	COG1554	hydrolase, family 65, central catalytic
C7N18_RS08315	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7N18_RS08320	COG3842	ATPase activity
C7N18_RS08330	COG1609	Transcriptional regulator
C7N18_RS08335	COG3106	COG3106 Predicted ATPase
C7N18_RS08345	COG3283	Transcriptional regulator of aromatic amino acids metabolism
C7N18_RS08350	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
C7N18_RS08355	COG4948	Mandelate Racemase Muconate Lactonizing
C7N18_RS08360	COG2866	Carboxypeptidase
C7N18_RS08365	COG0702	epimerase
C7N18_RS08375	COG1073	alpha beta
C7N18_RS08380	COG1073	alpha beta
C7N18_RS08385	COG0583	DNA-binding transcription factor activity
C7N18_RS08390	COG4166	transmembrane transport
C7N18_RS08395	COG0668	transmembrane transport
C7N18_RS08400	COG3182	Iron-regulated membrane protein
C7N18_RS08405	COG0589	response to stress
C7N18_RS08410	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7N18_RS08415	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C7N18_RS08420	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
C7N18_RS08425	COG1473	amidohydrolase
C7N18_RS08430	COG1473	amidohydrolase
C7N18_RS08435	COG0583	DNA-binding transcription factor activity
C7N18_RS08440	COG2840	Smr protein MutS2
C7N18_RS08445	COG3706	GGDEF domain
C7N18_RS08455	COG0513	Belongs to the DEAD box helicase family
C7N18_RS08465	COG0582	viral genome integration into host DNA
C7N18_RS08490	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C7N18_RS08565	COG2207	Transcriptional regulator
C7N18_RS08610	COG3772	lysozyme
C7N18_RS08645	COG4220	transposase activity
C7N18_RS08665	COG1030	water channel activity
C7N18_RS08750	COG5301	cellulose 1,4-beta-cellobiosidase activity
C7N18_RS08775	COG0589	response to stress
C7N18_RS08780	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C7N18_RS08785	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C7N18_RS08785	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
C7N18_RS08785	COG1013	pyruvate-flavodoxin oxidoreductase activity
C7N18_RS08785	COG0674	pyruvate-flavodoxin oxidoreductase activity
C7N18_RS08790	COG3042	response to heat
C7N18_RS08795	COG3187	Heat shock protein
C7N18_RS08800	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7N18_RS08805	COG2911	Protein conserved in bacteria
C7N18_RS08815	COG3784	Protein of unknown function (DUF1318)
C7N18_RS08830	COG3733	amine oxidase
C7N18_RS08835	COG1012	belongs to the aldehyde dehydrogenase family
C7N18_RS08835	COG2030	dehydratase
C7N18_RS08840	COG3396	Phenylacetate-CoA oxygenase
C7N18_RS08845	COG3460	Phenylacetate-CoA oxygenase
C7N18_RS08855	COG2151	metal-sulfur cluster biosynthetic enzyme
C7N18_RS08860	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C7N18_RS08865	COG1024	Enoyl-CoA hydratase
C7N18_RS08875	COG3327	negative regulation of DNA-templated transcription, initiation
C7N18_RS08880	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C7N18_RS08895	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C7N18_RS08900	COG4589	Belongs to the CDS family
C7N18_RS08905	COG2267	carboxylic ester hydrolase activity
C7N18_RS08910	COG0671	phosphoesterase, PA-phosphatase related
C7N18_RS08910	COG2453	phosphatase
C7N18_RS08920	COG1643	Atp-dependent helicase
C7N18_RS08925	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C7N18_RS08935	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C7N18_RS08940	COG3038	cytochrome b561
C7N18_RS08960	COG0840	transmembrane signaling receptor activity
C7N18_RS08965	COG0583	DNA-binding transcription factor activity
C7N18_RS08970	COG5383	Protein conserved in bacteria
C7N18_RS08980	COG2841	Protein conserved in bacteria
C7N18_RS08985	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7N18_RS08990	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C7N18_RS08995	COG1275	C4-dicarboxylate transporter malic acid transport protein
C7N18_RS09000	COG0500	methyltransferase
C7N18_RS09010	COG3135	benzoate transporter
C7N18_RS09015	COG1396	sequence-specific DNA binding
C7N18_RS09020	COG0826	peptidase U32
C7N18_RS09030	COG1724	mRNA binding
C7N18_RS09035	COG1598	PFAM Uncharacterised protein family UPF0150
C7N18_RS09040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7N18_RS09045	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C7N18_RS09050	COG3842	ATPase activity
C7N18_RS09055	COG1176	ABC-type spermidine putrescine transport system, permease component I
C7N18_RS09060	COG1177	transmembrane transport
C7N18_RS09085	COG3238	Protein conserved in bacteria
C7N18_RS09090	COG1247	-acetyltransferase
C7N18_RS09095	COG2130	NADP-dependent
C7N18_RS09100	COG1802	Transcriptional regulator
C7N18_RS09105	COG4772	TonB-dependent receptor
C7N18_RS09110	COG3391	amine dehydrogenase activity
C7N18_RS09115	COG1113	amino acid transport
C7N18_RS09120	COG0625	glutathione transferase activity
C7N18_RS09175	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C7N18_RS09180	COG2162	N-hydroxyarylamine O-acetyltransferase activity
C7N18_RS09185	COG0384	phenazine biosynthesis protein PhzF
C7N18_RS09190	COG2181	nitrate reductase activity
C7N18_RS09195	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C7N18_RS09200	COG1140	nitrate reductase beta subunit
C7N18_RS09205	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C7N18_RS09210	COG2223	nitrite transmembrane transporter activity
C7N18_RS09215	COG4886	Leucine-rich repeat (LRR) protein
C7N18_RS09220	COG4886	Leucine-rich repeat (LRR) protein
C7N18_RS09230	COG0697	spore germination
C7N18_RS09235	COG3383	formate dehydrogenase (NAD+) activity
C7N18_RS09235	COG0243	molybdopterin cofactor binding
C7N18_RS09240	COG0243	molybdopterin cofactor binding
C7N18_RS09240	COG3383	formate dehydrogenase (NAD+) activity
C7N18_RS09245	COG0437	4 iron, 4 sulfur cluster binding
C7N18_RS09250	COG2864	formate dehydrogenase
C7N18_RS09255	COG3093	addiction module antidote protein HigA
C7N18_RS09260	COG1064	alcohol dehydrogenase
C7N18_RS09280	COG1764	response to oxidative stress
C7N18_RS09285	COG1028	Short-chain dehydrogenase reductase Sdr
C7N18_RS09290	COG2610	gluconate transmembrane transporter activity
C7N18_RS09295	COG1250	3-hydroxyacyl-CoA dehydrogenase
C7N18_RS09305	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C7N18_RS09310	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C7N18_RS09320	COG4608	Belongs to the ABC transporter superfamily
C7N18_RS09325	COG0444	Belongs to the ABC transporter superfamily
C7N18_RS09330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7N18_RS09335	COG0601	transmembrane transport
C7N18_RS09345	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
C7N18_RS09350	COG2200	EAL domain
C7N18_RS09350	COG2202	Pas domain
C7N18_RS09350	COG2199	diguanylate cyclase activity
C7N18_RS09355	COG3706	GGDEF domain
C7N18_RS09360	COG1649	PFAM Uncharacterised BCR, COG1649
C7N18_RS09370	COG0076	glutamate decarboxylase activity
C7N18_RS09380	COG0612	Peptidase, M16
C7N18_RS09385	COG4771	TonB-dependent receptor
C7N18_RS09390	COG4178	(ABC) transporter
C7N18_RS09400	COG0641	radical SAM
C7N18_RS09405	COG3119	arylsulfatase activity
C7N18_RS09420	COG0243	molybdopterin cofactor binding
C7N18_RS09425	COG3539	Fimbrial protein
C7N18_RS09430	COG3539	Fimbrial protein
C7N18_RS09435	COG3539	Fimbrial protein
C7N18_RS09440	COG3188	usher protein
C7N18_RS09450	COG3539	Fimbrial protein
C7N18_RS09480	COG1396	sequence-specific DNA binding
C7N18_RS09495	COG1070	Carbohydrate kinase
C7N18_RS09505	COG1129	ABC transporter
C7N18_RS09540	COG3781	membrane
C7N18_RS09550	COG2199	diguanylate cyclase activity
C7N18_RS09560	COG2066	Belongs to the glutaminase family
C7N18_RS09565	COG1012	belongs to the aldehyde dehydrogenase family
C7N18_RS09570	COG0583	DNA-binding transcription factor activity
C7N18_RS09590	COG1846	Transcriptional regulator
C7N18_RS09595	COG4977	sequence-specific DNA binding
C7N18_RS09605	COG0697	spore germination
C7N18_RS09610	COG2814	Major facilitator Superfamily
C7N18_RS09630	COG1546	Belongs to the CinA family
C7N18_RS09635	COG0339	signal peptide processing
C7N18_RS09640	COG4221	oxidoreductase activity
C7N18_RS09645	COG1802	Transcriptional regulator
C7N18_RS09655	COG0246	Mannitol dehydrogenase
C7N18_RS09705	COG5301	cellulose 1,4-beta-cellobiosidase activity
C7N18_RS09810	COG4220	transposase activity
C7N18_RS09845	COG3772	lysozyme
C7N18_RS09910	COG0484	heat shock protein binding
C7N18_RS09915	COG1403	HNH endonuclease
C7N18_RS10000	COG1846	Transcriptional regulator
C7N18_RS10025	COG1396	sequence-specific DNA binding
C7N18_RS10055	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C7N18_RS10065	COG0582	viral genome integration into host DNA
C7N18_RS10075	COG1063	alcohol dehydrogenase
C7N18_RS10095	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7N18_RS10110	COG0243	molybdopterin cofactor binding
C7N18_RS10115	COG0243	molybdopterin cofactor binding
C7N18_RS10130	COG0437	4 iron, 4 sulfur cluster binding
C7N18_RS10135	COG3302	dmso reductase anchor subunit
C7N18_RS10140	COG3381	protein complex oligomerization
C7N18_RS10150	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C7N18_RS10155	COG1940	carbohydrate kinase activity
C7N18_RS10160	COG0583	DNA-binding transcription factor activity
C7N18_RS10165	COG2814	Major facilitator Superfamily
C7N18_RS10180	COG3591	Belongs to the peptidase S1B family
C7N18_RS10200	COG0628	permease
C7N18_RS10205	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
C7N18_RS10210	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
C7N18_RS10220	COG0531	amino acid
C7N18_RS10230	COG3136	membrane protein required for alginate biosynthesis
C7N18_RS10235	COG0745	RESPONSE REGULATOR receiver
C7N18_RS10255	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C7N18_RS10255	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C7N18_RS10265	COG5339	Protein conserved in bacteria
C7N18_RS10280	COG3250	beta-galactosidase activity
C7N18_RS10285	COG1309	transcriptional regulator
C7N18_RS10290	COG1028	Short-chain dehydrogenase reductase Sdr
C7N18_RS10300	COG1263	PTS System
C7N18_RS10300	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7N18_RS10305	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C7N18_RS10315	COG0673	inositol 2-dehydrogenase activity
C7N18_RS10355	COG4659	FMN binding
C7N18_RS10365	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C7N18_RS10370	COG3104	oligopeptide transport
C7N18_RS10375	COG0625	glutathione transferase activity
C7N18_RS10380	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
C7N18_RS10395	COG3895	Periplasmic Protein
C7N18_RS10405	COG3133	Outer membrane lipoprotein
C7N18_RS10420	COG1566	PFAM secretion protein HlyD family protein
C7N18_RS10425	COG1289	transmembrane transporter activity
C7N18_RS10435	COG4989	oxidoreductase activity
C7N18_RS10440	COG3313	Fe-S protein
C7N18_RS10445	COG1309	transcriptional regulator
C7N18_RS10450	COG1902	pentaerythritol trinitrate reductase activity
C7N18_RS10455	COG0346	lactoylglutathione lyase activity
C7N18_RS10470	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C7N18_RS10475	COG0791	NLP P60 protein
C7N18_RS10480	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C7N18_RS10485	COG2814	Major facilitator Superfamily
C7N18_RS10500	COG0583	DNA-binding transcription factor activity
C7N18_RS10505	COG2814	Major facilitator Superfamily
C7N18_RS10515	COG0307	riboflavin synthase, alpha
C7N18_RS10525	COG3468	outer membrane autotransporter barrel domain protein
C7N18_RS10545	COG4529	Protein conserved in bacteria
C7N18_RS10555	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
C7N18_RS10560	COG0437	4 iron, 4 sulfur cluster binding
C7N18_RS10570	COG2414	aldehyde ferredoxin oxidoreductase
C7N18_RS10575	COG0437	4 iron, 4 sulfur cluster binding
C7N18_RS10585	COG0469	pyruvate kinase activity
C7N18_RS10590	COG4238	major outer membrane lipoprotein
C7N18_RS10595	COG1376	ErfK ybiS ycfS ynhG family protein
C7N18_RS10610	COG0719	Fe-S assembly protein
C7N18_RS10615	COG0396	ATPase activity
C7N18_RS10620	COG0719	Fe-S assembly protein
C7N18_RS10625	COG0316	Belongs to the HesB IscA family
C7N18_RS10635	COG2050	protein possibly involved in aromatic compounds catabolism
C7N18_RS10640	COG0277	FAD linked oxidase domain protein
C7N18_RS10640	COG0247	lactate metabolic process
C7N18_RS10645	COG0628	permease
C7N18_RS10660	COG0738	Major facilitator superfamily
C7N18_RS10665	COG2271	Major facilitator Superfamily
C7N18_RS10680	COG4670	ketone body catabolic process
C7N18_RS10690	COG1917	Cupin 2, conserved barrel domain protein
C7N18_RS10690	COG2207	Transcriptional regulator
C7N18_RS10695	COG2086	electron transfer activity
C7N18_RS10700	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C7N18_RS10705	COG0644	oxidoreductase
C7N18_RS10710	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C7N18_RS10715	COG0318	PFAM AMP-dependent synthetase and ligase
C7N18_RS10720	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C7N18_RS10720	COG0574	Belongs to the PEP-utilizing enzyme family
C7N18_RS10730	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C7N18_RS10735	COG4256	Hemin uptake protein
C7N18_RS10745	COG2200	EAL domain
C7N18_RS10750	COG0791	NLP P60 protein
C7N18_RS10775	COG0072	phenylalanine-tRNA ligase activity
C7N18_RS10775	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7N18_RS10820	COG3137	Salt-induced outer membrane protein
C7N18_RS10825	COG1105	Belongs to the carbohydrate kinase PfkB family
C7N18_RS10835	COG3001	Fructosamine kinase
C7N18_RS10845	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7N18_RS10850	COG1988	membrane-bound metal-dependent
C7N18_RS10855	COG1823	symporter activity
C7N18_RS10870	COG0753	catalase activity
C7N18_RS10880	COG1486	melibiose metabolic process
C7N18_RS10885	COG1917	Cupin 2, conserved barrel domain protein
C7N18_RS10885	COG2169	Transcriptional regulator
C7N18_RS10890	COG1447	Phosphotransferase system cellobiose-specific component IIA
C7N18_RS10900	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7N18_RS10910	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C7N18_RS10920	COG0322	excinuclease ABC activity
C7N18_RS10930	COG3678	ATP-independent chaperone mediated protein folding
C7N18_RS10960	COG0708	Exodeoxyribonuclease III
C7N18_RS10965	COG0398	Pfam SNARE associated Golgi protein
C7N18_RS10975	COG0398	Pfam SNARE associated Golgi protein
C7N18_RS10980	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C7N18_RS10985	COG4134	Bacterial extracellular solute-binding protein
C7N18_RS10990	COG4135	transport system, permease component
C7N18_RS10995	COG4136	ATPase activity
C7N18_RS11000	COG2897	thiosulfate sulfurtransferase activity
C7N18_RS11005	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C7N18_RS11010	COG0494	nUDIX hydrolase
C7N18_RS11020	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C7N18_RS11030	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C7N18_RS11035	COG0709	Synthesizes selenophosphate from selenide and ATP
C7N18_RS11040	COG0778	Nitroreductase
C7N18_RS11045	COG0616	signal peptide processing
C7N18_RS11055	COG0252	asparaginase activity
C7N18_RS11060	COG1335	isochorismatase
C7N18_RS11065	COG2814	Major facilitator Superfamily
C7N18_RS11070	COG1349	DNA-binding transcription factor activity
C7N18_RS11075	COG0667	Aldo Keto reductase
C7N18_RS11080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7N18_RS11085	COG0191	fructose-bisphosphate aldolase activity
C7N18_RS11090	COG1063	alcohol dehydrogenase
C7N18_RS11095	COG2271	Major facilitator Superfamily
C7N18_RS11100	COG1063	alcohol dehydrogenase
C7N18_RS11105	COG3139	Protein of unknown function (DUF1315)
C7N18_RS11115	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C7N18_RS11120	COG0676	glucose-6-phosphate 1-epimerase activity
C7N18_RS11130	COG3713	MltA-interacting MipA family protein
C7N18_RS11135	COG2766	serine protein kinase
C7N18_RS11150	COG2199	diguanylate cyclase activity
C7N18_RS11155	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C7N18_RS11170	COG2207	Transcriptional regulator
C7N18_RS11175	COG2807	transmembrane transport
C7N18_RS11180	COG3189	MarR family transcriptional regulator
C7N18_RS11185	COG3042	response to heat
C7N18_RS11190	COG2199	diguanylate cyclase activity
C7N18_RS11190	COG2203	Gaf domain
C7N18_RS11205	COG2261	transglycosylase associated protein
C7N18_RS11215	COG3615	Tellurite resistance protein tehB
C7N18_RS11225	COG0583	DNA-binding transcription factor activity
C7N18_RS11230	COG0473	3-isopropylmalate dehydrogenase activity
C7N18_RS11240	COG4638	Rieske (2fe-2S)
C7N18_RS11245	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C7N18_RS11250	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
C7N18_RS11255	COG0318	PFAM AMP-dependent synthetase and ligase
C7N18_RS11260	COG3065	identical protein binding
C7N18_RS11265	COG1214	PFAM Peptidase M22, glycoprotease
C7N18_RS11270	COG1199	ATP-dependent helicase activity
C7N18_RS11275	COG0251	oxidation-reduction process
C7N18_RS11290	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C7N18_RS11300	COG1760	l-serine dehydratase
C7N18_RS11305	COG2200	EAL domain
C7N18_RS11315	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7N18_RS11315	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7N18_RS11320	COG3715	PTS system
C7N18_RS11325	COG3716	PTS system mannose fructose sorbose family IID component
C7N18_RS11340	COG2226	methyltransferase
C7N18_RS11370	COG1414	Transcriptional regulator
C7N18_RS11375	COG2814	Major facilitator Superfamily
C7N18_RS11385	COG0793	Belongs to the peptidase S41A family
C7N18_RS11395	COG1956	GAF domain-containing protein
C7N18_RS11400	COG2995	paraquat-inducible protein a
C7N18_RS11425	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C7N18_RS11435	COG1276	copper resistance
C7N18_RS11440	COG2372	response to copper ion
C7N18_RS11450	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7N18_RS11455	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C7N18_RS11460	COG1770	oligopeptidase
C7N18_RS11465	COG2979	Protein of unknown function (DUF533)
C7N18_RS11475	COG3141	response to X-ray
C7N18_RS11485	COG0800	Aldolase
C7N18_RS11490	COG0129	dihydroxy-acid dehydratase activity
C7N18_RS11495	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C7N18_RS11500	COG1737	Transcriptional regulator
C7N18_RS11505	COG0469	pyruvate kinase activity
C7N18_RS11510	COG1560	Kdo2-lipid A biosynthetic process
C7N18_RS11515	COG0739	heme binding
C7N18_RS11520	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
C7N18_RS11530	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7N18_RS11560	COG0217	transcriptional regulatory protein
C7N18_RS11565	COG0494	nUDIX hydrolase
C7N18_RS11610	COG5301	cellulose 1,4-beta-cellobiosidase activity
C7N18_RS11745	COG3772	lysozyme
C7N18_RS11810	COG0305	Participates in initiation and elongation during chromosome replication
C7N18_RS11815	COG1484	DNA-dependent DNA replication
C7N18_RS11830	COG3646	Phage regulatory protein
C7N18_RS11850	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C7N18_RS11925	COG0582	viral genome integration into host DNA
C7N18_RS11930	COG1801	Protein of unknown function DUF72
C7N18_RS11935	COG3788	relative of glutathione S-transferase, MAPEG superfamily
C7N18_RS11950	COG0243	molybdopterin cofactor binding
C7N18_RS11955	COG3005	denitrification pathway
C7N18_RS11965	COG3102	Protein conserved in bacteria
C7N18_RS11975	COG3755	Protein conserved in bacteria
C7N18_RS11985	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C7N18_RS11990	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C7N18_RS11995	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
C7N18_RS12000	COG0745	RESPONSE REGULATOR receiver
C7N18_RS12010	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C7N18_RS12020	COG0840	transmembrane signaling receptor activity
C7N18_RS12025	COG0835	chemotaxis
C7N18_RS12030	COG2198	Histidine kinase
C7N18_RS12030	COG0643	Histidine kinase
C7N18_RS12035	COG1360	Flagellar Motor Protein
C7N18_RS12040	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C7N18_RS12055	COG0589	response to stress
C7N18_RS12065	COG1877	trehalose-phosphatase activity
C7N18_RS12070	COG1172	Belongs to the binding-protein-dependent transport system permease family
C7N18_RS12075	COG1129	ABC transporter
C7N18_RS12080	COG1879	ABC-type sugar transport system periplasmic component
C7N18_RS12105	COG1528	Iron-storage protein
C7N18_RS12115	COG0814	amino acid
C7N18_RS12120	COG3012	SEC-C Motif Domain Protein
C7N18_RS12120	COG3318	Belongs to the UPF0149 family
C7N18_RS12185	COG4974	Belongs to the 'phage' integrase family
C7N18_RS12270	COG0464	growth
C7N18_RS12280	COG4695	Portal protein
C7N18_RS12395	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C7N18_RS12485	COG2197	response regulator
C7N18_RS12500	COG2197	response regulator
C7N18_RS12505	COG1126	abc transporter atp-binding protein
C7N18_RS12510	COG0765	amino acid transport
C7N18_RS12520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7N18_RS12530	COG1191	sigma factor activity
C7N18_RS12540	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C7N18_RS12545	COG1516	flagellar protein fliS
C7N18_RS12555	COG0366	Alpha amylase catalytic
C7N18_RS12565	COG2391	methyltransferase activity
C7N18_RS12570	COG0425	Belongs to the sulfur carrier protein TusA family
C7N18_RS12575	COG2135	peptidase activity
C7N18_RS12600	COG1766	The M ring may be actively involved in energy transduction
C7N18_RS12605	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C7N18_RS12610	COG1317	bacterial-type flagellum organization
C7N18_RS12615	COG1157	protein secretion by the type III secretion system
C7N18_RS12620	COG2882	bacterial-type flagellum organization
C7N18_RS12625	COG3144	bacterial-type flagellum assembly
C7N18_RS12630	COG1580	Controls the rotational direction of flagella during chemotaxis
C7N18_RS12635	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C7N18_RS12640	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C7N18_RS12645	COG3190	flagellar
C7N18_RS12655	COG1987	bacterial-type flagellum assembly
C7N18_RS12660	COG1684	flagellar biosynthetic protein fliR
C7N18_RS12665	COG2197	response regulator
C7N18_RS12690	COG3706	GGDEF domain
C7N18_RS12695	COG5475	Uncharacterized small protein (DUF2158)
C7N18_RS12700	COG2354	Protein conserved in bacteria
C7N18_RS12710	COG3727	T/G mismatch-specific endonuclease activity
C7N18_RS12715	COG0270	DNA (cytosine-5-)-methyltransferase activity
C7N18_RS12720	COG1418	mRNA catabolic process
C7N18_RS12730	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C7N18_RS12745	COG2205	protein histidine kinase activity
C7N18_RS12750	COG0745	RESPONSE REGULATOR receiver
C7N18_RS12755	COG2351	hydroxyisourate hydrolase activity
C7N18_RS12770	COG3443	Belongs to the bacterial solute-binding protein 9 family
C7N18_RS12775	COG3038	cytochrome b561
C7N18_RS12825	COG5301	cellulose 1,4-beta-cellobiosidase activity
C7N18_RS12840	COG2032	superoxide dismutase activity
C7N18_RS12940	COG4220	transposase activity
C7N18_RS12975	COG3772	lysozyme
C7N18_RS13035	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C7N18_RS13040	COG1403	HNH endonuclease
C7N18_RS13050	COG3111	PFAM Bacterial OB fold (BOF) protein
C7N18_RS13085	COG1846	Transcriptional regulator
C7N18_RS13130	COG0582	viral genome integration into host DNA
C7N18_RS13155	COG3093	addiction module antidote protein HigA
C7N18_RS13160	COG3423	Transcriptional regulator
C7N18_RS13215	COG0477	Major facilitator Superfamily
C7N18_RS13220	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C7N18_RS13225	COG0217	transcriptional regulatory protein
C7N18_RS13235	COG0534	Mate efflux family protein
C7N18_RS13245	COG0583	DNA-binding transcription factor activity
C7N18_RS13250	COG0583	DNA-binding transcription factor activity
C7N18_RS13260	COG1376	ErfK ybiS ycfS ynhG family protein
C7N18_RS13275	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
C7N18_RS13295	COG3436	PFAM IS66 Orf2 family protein
C7N18_RS13385	COG2003	Belongs to the UPF0758 family
C7N18_RS13430	COG1289	transmembrane transporter activity
C7N18_RS13440	COG1686	Belongs to the peptidase S11 family
C7N18_RS13455	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C7N18_RS13585	COG1783	phage Terminase large subunit
C7N18_RS13830	COG0582	viral genome integration into host DNA
C7N18_RS13835	COG2925	Exonuclease
C7N18_RS13840	COG0425	Belongs to the sulfur carrier protein TusA family
C7N18_RS13845	COG2391	methyltransferase activity
C7N18_RS13850	COG0531	amino acid
C7N18_RS13860	COG0583	DNA-binding transcription factor activity
C7N18_RS13865	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7N18_RS13870	COG4115	mRNA cleavage
C7N18_RS13875	COG2161	toxin-antitoxin pair type II binding
C7N18_RS13890	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C7N18_RS13900	COG0131	Imidazoleglycerol-phosphate dehydratase
C7N18_RS13900	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C7N18_RS13905	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C7N18_RS13940	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C7N18_RS14010	COG2089	acid synthase
C7N18_RS14020	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C7N18_RS14030	COG0438	transferase activity, transferring glycosyl groups
C7N18_RS14035	COG2327	Polysaccharide pyruvyl transferase
C7N18_RS14040	COG2244	polysaccharide biosynthetic process
C7N18_RS14045	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C7N18_RS14050	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7N18_RS14055	COG0662	Cupin 2, conserved barrel domain protein
C7N18_RS14055	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
C7N18_RS14060	COG0297	glycogen (starch) synthase activity
C7N18_RS14065	COG1051	belongs to the nudix hydrolase family
C7N18_RS14070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7N18_RS14075	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
C7N18_RS14080	COG0110	maltose O-acetyltransferase activity
C7N18_RS14085	COG1216	Glycosyl transferase, family 2
C7N18_RS14095	COG0438	transferase activity, transferring glycosyl groups
C7N18_RS14100	COG1045	serine acetyltransferase
C7N18_RS14105	COG0463	Glycosyl transferase, family 2
C7N18_RS14110	COG3206	protein involved in exopolysaccharide biosynthesis
C7N18_RS14110	COG0489	protein tyrosine kinase activity
C7N18_RS14115	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7N18_RS14120	COG1596	polysaccharide export
C7N18_RS14125	COG1253	flavin adenine dinucleotide binding
C7N18_RS14130	COG2982	Protein involved in outer membrane biogenesis
C7N18_RS14140	COG0572	uridine kinase
C7N18_RS14145	COG3447	MASE1 domain protein
C7N18_RS14145	COG5001	Diguanylate cyclase
C7N18_RS14145	COG5002	protein histidine kinase activity
C7N18_RS14150	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C7N18_RS14155	COG0443	Heat shock 70 kDa protein
C7N18_RS14160	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
C7N18_RS14165	COG0631	protein serine/threonine phosphatase activity
C7N18_RS14170	COG4245	von Willebrand factor, type A
C7N18_RS14215	COG2205	protein histidine kinase activity
C7N18_RS14220	COG0745	RESPONSE REGULATOR receiver
C7N18_RS14230	COG0826	peptidase U32
C7N18_RS14260	COG3775	system Galactitol-specific IIC component
C7N18_RS14265	COG3414	Phosphotransferase system galactitol-specific IIB component
C7N18_RS14270	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7N18_RS14285	COG1830	Aldolase
C7N18_RS14290	COG2211	Major facilitator Superfamily
C7N18_RS14295	COG1397	ADP-ribosylglycohydrolase
C7N18_RS14300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7N18_RS14305	COG2188	Transcriptional regulator
C7N18_RS14310	COG3757	hydrolase, family 25
C7N18_RS14315	COG0351	phosphomethylpyrimidine kinase
C7N18_RS14335	COG5455	response to cobalt ion
C7N18_RS14340	COG3539	Fimbrial protein
C7N18_RS14345	COG3188	usher protein
C7N18_RS14350	COG3121	Chaperone
C7N18_RS14355	COG3539	Fimbrial protein
C7N18_RS14365	COG0489	protein tyrosine kinase activity
C7N18_RS14390	COG3831	ATPase activity
C7N18_RS14400	COG0714	Associated with various cellular activities
C7N18_RS14405	COG2425	protein containing a von Willebrand factor type A (vWA) domain
C7N18_RS14415	COG4715	Zinc finger, swim domain protein
C7N18_RS14420	COG4808	Protein conserved in bacteria
C7N18_RS14425	COG4807	Protein conserved in bacteria
C7N18_RS14430	COG3279	Response regulator of the LytR AlgR family
C7N18_RS14435	COG3275	phosphorelay sensor kinase activity
C7N18_RS14490	COG5301	cellulose 1,4-beta-cellobiosidase activity
C7N18_RS14650	COG3772	lysozyme
C7N18_RS14700	COG1174	glycine betaine transport
C7N18_RS14705	COG1125	glycine betaine transport
C7N18_RS14710	COG1174	glycine betaine transport
C7N18_RS14715	COG1732	Glycine betaine
C7N18_RS14720	COG1472	Belongs to the glycosyl hydrolase 3 family
C7N18_RS14725	COG0277	FAD linked oxidase domain protein
C7N18_RS14730	COG1686	Belongs to the peptidase S11 family
C7N18_RS14740	COG0586	Pfam SNARE associated Golgi protein
C7N18_RS14745	COG1028	Short-chain dehydrogenase reductase Sdr
C7N18_RS14760	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7N18_RS14770	COG1346	cytolysis
C7N18_RS14780	COG2949	membrane
C7N18_RS14790	COG0493	'glutamate synthase
C7N18_RS14795	COG0167	dihydroorotate dehydrogenase activity
C7N18_RS14795	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
C7N18_RS14800	COG4211	Belongs to the binding-protein-dependent transport system permease family
C7N18_RS14805	COG1129	ABC transporter
C7N18_RS14810	COG1879	ABC-type sugar transport system periplasmic component
C7N18_RS14815	COG1609	Transcriptional regulator
C7N18_RS14820	COG2311	Membrane
C7N18_RS14830	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
C7N18_RS14835	COG4771	TonB-dependent receptor
C7N18_RS14845	COG0833	amino acid
C7N18_RS14850	COG0583	DNA-binding transcription factor activity
C7N18_RS14855	COG2855	membrane
C7N18_RS14865	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7N18_RS14865	COG1522	sequence-specific DNA binding
C7N18_RS14870	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7N18_RS14880	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7N18_RS14885	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7N18_RS14890	COG2313	pseudouridylate synthase activity
C7N18_RS14895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7N18_RS14900	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7N18_RS14900	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7N18_RS14900	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
C7N18_RS14905	COG1105	Belongs to the carbohydrate kinase PfkB family
C7N18_RS14915	COG2814	Major facilitator Superfamily
C7N18_RS14930	COG0246	Mannitol dehydrogenase
C7N18_RS14935	COG0523	cobalamin synthesis protein
C7N18_RS14940	COG0671	phosphoesterase, PA-phosphatase related
C7N18_RS14945	COG0791	NLP P60 protein
C7N18_RS14950	COG2200	EAL domain
C7N18_RS14955	COG4166	transmembrane transport
C7N18_RS14960	COG4174	ABC transporter (Permease)
C7N18_RS14965	COG4239	(ABC) transporter, permease
C7N18_RS14970	COG4172	Belongs to the ABC transporter superfamily
C7N18_RS14980	COG2814	Major facilitator Superfamily
C7N18_RS14985	COG1187	pseudouridine synthase activity
C7N18_RS14990	COG1061	Type III restriction enzyme res subunit
C7N18_RS15010	COG3083	sulfuric ester hydrolase activity
C7N18_RS15020	COG3468	outer membrane autotransporter barrel domain protein
C7N18_RS15025	COG2197	response regulator
C7N18_RS15030	COG3088	subunit of a heme lyase
C7N18_RS15030	COG4235	cytochrome complex assembly
C7N18_RS15035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7N18_RS15040	COG1138	Cytochrome C-type biogenesis protein
C7N18_RS15050	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C7N18_RS15060	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C7N18_RS15070	COG3005	denitrification pathway
C7N18_RS15075	COG3043	anaerobic respiration
C7N18_RS15080	COG0348	domain, Protein
C7N18_RS15085	COG0437	4 iron, 4 sulfur cluster binding
C7N18_RS15095	COG3062	negative regulation of establishment of protein localization
C7N18_RS15100	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
C7N18_RS15100	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C7N18_RS15115	COG4615	Cyclic peptide transporter
C7N18_RS15125	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C7N18_RS15125	COG2169	Transcriptional regulator
C7N18_RS15130	COG1477	protein flavinylation
C7N18_RS15135	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C7N18_RS15140	COG0642	Histidine kinase
C7N18_RS15140	COG2198	Histidine kinase
C7N18_RS15145	COG2197	response regulator
C7N18_RS15150	COG0784	Response regulator, receiver
C7N18_RS15150	COG2205	protein histidine kinase activity
C7N18_RS15155	COG4676	Protein conserved in bacteria
C7N18_RS15170	COG3234	Protein of unknown function (DUF1175)
C7N18_RS15175	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
C7N18_RS15180	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C7N18_RS15190	COG3468	outer membrane autotransporter barrel domain protein
C7N18_RS15195	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7N18_RS15200	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7N18_RS15205	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C7N18_RS15215	COG2814	Major facilitator Superfamily
C7N18_RS15220	COG0583	DNA-binding transcription factor activity
C7N18_RS15225	COG0584	glycerophosphoryl diester phosphodiesterase
C7N18_RS15230	COG2271	Major facilitator Superfamily
C7N18_RS15235	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C7N18_RS15245	COG0247	lactate metabolic process
C7N18_RS15250	COG5464	transposase or invertase
C7N18_RS15260	COG3836	Belongs to the HpcH HpaI aldolase family
C7N18_RS15265	COG2271	Major facilitator Superfamily
C7N18_RS15275	COG1414	Transcriptional regulator
C7N18_RS15340	COG0318	PFAM AMP-dependent synthetase and ligase
C7N18_RS15350	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C7N18_RS15365	COG1169	isochorismate synthase
C7N18_RS15370	COG4575	ribosome binding
C7N18_RS15375	COG2153	protein acetylation
C7N18_RS15385	COG5160	protein modification by small protein removal
C7N18_RS15405	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C7N18_RS15410	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C7N18_RS15420	COG0839	Belongs to the complex I subunit 6 family
C7N18_RS15435	COG1034	ATP synthesis coupled electron transport
C7N18_RS15440	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
C7N18_RS15445	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
C7N18_RS15465	COG0583	DNA-binding transcription factor activity
C7N18_RS15470	COG0436	Aminotransferase
C7N18_RS15480	COG0471	metal ion transport
C7N18_RS15480	COG0490	domain, Protein
C7N18_RS15485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7N18_RS15500	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C7N18_RS15505	COG0280	phosphate acetyltransferase
C7N18_RS15505	COG0857	belongs to the CobB CobQ family
C7N18_RS15510	COG1288	antiporter activity
C7N18_RS15515	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
C7N18_RS15520	COG0622	Phosphoesterase
C7N18_RS15525	COG0625	glutathione transferase activity
C7N18_RS15530	COG0625	glutathione transferase activity
C7N18_RS15535	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C7N18_RS15540	COG1090	epimerase
C7N18_RS15545	COG5464	transposase or invertase
C7N18_RS15550	COG4598	ABC transporter
C7N18_RS15555	COG4160	amino acid transport
C7N18_RS15560	COG4215	(ABC) transporter
C7N18_RS15565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7N18_RS15570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7N18_RS15575	COG0163	prenyltransferase activity
C7N18_RS15580	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C7N18_RS15585	COG1286	toxin biosynthetic process
C7N18_RS15590	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
C7N18_RS15595	COG0285	dihydrofolate synthase activity
C7N18_RS15605	COG0586	Pfam SNARE associated Golgi protein
C7N18_RS15615	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C7N18_RS15630	COG2814	Major facilitator Superfamily
C7N18_RS15635	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C7N18_RS15650	COG3101	peptidyl-lysine hydroxylation
C7N18_RS15655	COG0730	response to heat
C7N18_RS15670	COG2890	protein-(glutamine-N5) methyltransferase activity
C7N18_RS15685	COG3539	Fimbrial protein
C7N18_RS15690	COG3539	Fimbrial protein
C7N18_RS15695	COG3539	Fimbrial protein
C7N18_RS15700	COG3121	Chaperone
C7N18_RS15705	COG3188	usher protein
C7N18_RS15710	COG3539	Fimbrial protein
C7N18_RS15715	COG2062	phosphohistidine phosphatase, SixA
C7N18_RS15730	COG3691	Protein conserved in bacteria
C7N18_RS15745	COG2853	Lipoprotein
C7N18_RS15760	COG0583	DNA-binding transcription factor activity
C7N18_RS15765	COG2610	gluconate transmembrane transporter activity
C7N18_RS15775	COG0477	Major facilitator Superfamily
C7N18_RS15780	COG1566	PFAM secretion protein HlyD family protein
C7N18_RS15785	COG2197	response regulator
C7N18_RS15790	COG0784	Response regulator, receiver
C7N18_RS15790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7N18_RS15790	COG2198	Histidine kinase
C7N18_RS15790	COG2205	protein histidine kinase activity
C7N18_RS15795	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C7N18_RS15800	COG0679	Auxin Efflux Carrier
C7N18_RS15805	COG0028	Belongs to the TPP enzyme family
C7N18_RS15830	COG1560	Kdo2-lipid A biosynthetic process
C7N18_RS15840	COG0436	Aminotransferase
C7N18_RS15845	COG3275	phosphorelay sensor kinase activity
C7N18_RS15850	COG3279	Response regulator of the LytR AlgR family
C7N18_RS15855	COG2207	Transcriptional regulator
C7N18_RS15865	COG1363	Peptidase, m42
C7N18_RS15870	COG0006	proline dipeptidase activity
C7N18_RS15875	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7N18_RS15880	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7N18_RS15905	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7N18_RS15910	COG2200	EAL domain
C7N18_RS15910	COG2199	diguanylate cyclase activity
C7N18_RS15925	COG3415	Transposase
C7N18_RS15930	COG3415	Transposase
C7N18_RS15935	COG0675	Transposase, IS605 OrfB family
C7N18_RS15975	COG0583	DNA-binding transcription factor activity
C7N18_RS15980	COG0385	Bile acid
C7N18_RS15985	COG3530	Putative quorum-sensing-regulated virulence factor
C7N18_RS16005	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7N18_RS16010	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7N18_RS16015	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C7N18_RS16020	COG2190	(PTS) system
C7N18_RS16035	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7N18_RS16040	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C7N18_RS16045	COG4208	sulfate ABC transporter
C7N18_RS16050	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
C7N18_RS16055	COG4150	thiosulfate binding
C7N18_RS16060	COG1028	Short-chain dehydrogenase reductase Sdr
C7N18_RS16075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7N18_RS16075	COG1263	PTS System
C7N18_RS16080	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7N18_RS16085	COG2837	iron assimilation
C7N18_RS16105	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7N18_RS16115	COG2207	Transcriptional regulator
C7N18_RS16120	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
C7N18_RS16125	COG4816	utilization protein
C7N18_RS16140	COG4819	ethanolamine utilization protein
C7N18_RS16145	COG3192	ethanolamine utilization protein
C7N18_RS16150	COG1454	alcohol dehydrogenase
C7N18_RS16155	COG4820	ethanolamine utilization protein (EutJ)
C7N18_RS16160	COG1012	belongs to the aldehyde dehydrogenase family
C7N18_RS16165	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
C7N18_RS16170	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
C7N18_RS16175	COG0280	phosphate acetyltransferase
C7N18_RS16180	COG4812	Cobalamin adenosyltransferase
C7N18_RS16185	COG4766	ethanolamine catabolic process
C7N18_RS16190	COG4917	ethanolamine utilization protein
C7N18_RS16195	COG4810	utilization protein
C7N18_RS16200	COG0281	malic enzyme
C7N18_RS16200	COG0280	phosphate acetyltransferase
C7N18_RS16205	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C7N18_RS16210	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C7N18_RS16215	COG5342	invasion associated locus B
C7N18_RS16225	COG0493	'glutamate synthase
C7N18_RS16225	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C7N18_RS16240	COG3850	Histidine kinase
C7N18_RS16245	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C7N18_RS16255	COG1393	Belongs to the ArsC family
C7N18_RS16270	COG0400	carboxylic ester hydrolase activity
C7N18_RS16280	COG2321	neutral zinc metallopeptidase
C7N18_RS16290	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
C7N18_RS16300	COG2716	regulation of RNA biosynthetic process
C7N18_RS16305	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C7N18_RS16310	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C7N18_RS16315	COG0651	ATP synthesis coupled electron transport
C7N18_RS16320	COG0650	Formate hydrogenlyase subunit 4
C7N18_RS16325	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C7N18_RS16330	COG4237	Hydrogenase 4 membrane
C7N18_RS16340	COG3261	NADH dehydrogenase
C7N18_RS16340	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
C7N18_RS16345	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C7N18_RS16350	COG3260	NADH ubiquinone oxidoreductase 20
C7N18_RS16360	COG3604	Transcriptional regulator
C7N18_RS16370	COG3547	Transposase (IS116 IS110 IS902 family)
C7N18_RS16375	COG2116	formate transmembrane transporter activity
C7N18_RS16380	COG0628	permease
C7N18_RS16385	COG4783	chaperone-mediated protein folding
C7N18_RS16390	COG1393	Belongs to the ArsC family
C7N18_RS16400	COG2233	PERMEase
C7N18_RS16415	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C7N18_RS16425	COG0248	Ppx GppA phosphatase
C7N18_RS16430	COG2200	EAL domain
C7N18_RS16440	COG3133	Outer membrane lipoprotein
C7N18_RS16455	COG0517	IMP dehydrogenase activity
C7N18_RS16455	COG0516	GMP reductase activity
C7N18_RS16480	COG1645	bacterial-type flagellum-dependent swarming motility
C7N18_RS16495	COG2976	Protein conserved in bacteria
C7N18_RS16525	COG4953	penicillin-binding protein 1C
C7N18_RS16530	COG2373	Large extracellular alpha-helical protein
C7N18_RS16550	COG2975	iron-sulfur cluster assembly
C7N18_RS16555	COG0633	Ferredoxin
C7N18_RS16575	COG0822	iron-sulfur transferase activity
C7N18_RS16595	COG0483	inositol monophosphate 1-phosphatase activity
C7N18_RS16600	COG1073	alpha beta
C7N18_RS16605	COG3711	transcriptional antiterminator
C7N18_RS16615	COG0583	DNA-binding transcription factor activity
C7N18_RS16620	COG4638	Rieske (2fe-2S)
C7N18_RS16645	COG1879	ABC-type sugar transport system periplasmic component
C7N18_RS16650	COG0457	Tetratricopeptide repeat
C7N18_RS16655	COG1940	carbohydrate kinase activity
C7N18_RS16665	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C7N18_RS16665	COG1017	nitric oxide dioxygenase activity
C7N18_RS16670	COG0347	Belongs to the P(II) protein family
C7N18_RS16675	COG2204	response regulator
C7N18_RS16680	COG3170	Tfp pilus assembly protein FimV
C7N18_RS16685	COG2205	protein histidine kinase activity
C7N18_RS16690	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C7N18_RS16690	COG0047	phosphoribosylformylglycinamidine synthase activity
C7N18_RS16700	COG0590	tRNA wobble adenosine to inosine editing
C7N18_RS16705	COG0560	Phosphoserine phosphatase
C7N18_RS16710	COG1737	Transcriptional regulator
C7N18_RS16715	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C7N18_RS16730	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
C7N18_RS16750	COG0681	Belongs to the peptidase S26 family
C7N18_RS16760	COG3086	response to oxidative stress
C7N18_RS16765	COG3026	antisigma factor binding
C7N18_RS16770	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
C7N18_RS16775	COG1595	DNA-templated transcription, initiation
C7N18_RS16795	COG0513	Belongs to the DEAD box helicase family
C7N18_RS16800	COG0583	DNA-binding transcription factor activity
C7N18_RS16820	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7N18_RS16825	COG3118	belongs to the thioredoxin family
C7N18_RS16830	COG3148	PFAM DTW domain containing protein
C7N18_RS16835	COG1042	CoA-binding domain protein
C7N18_RS16835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7N18_RS16835	COG0045	succinate-CoA ligase (ADP-forming) activity
C7N18_RS16840	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7N18_RS16845	COG5544	Lipoprotein
C7N18_RS16875	COG0542	response to heat
C7N18_RS16885	COG0564	pseudouridine synthase activity
C7N18_RS16890	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C7N18_RS16895	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C7N18_RS16905	COG0077	Prephenate dehydratase
C7N18_RS16905	COG1605	Chorismate mutase
C7N18_RS16910	COG0287	Prephenate dehydrogenase
C7N18_RS16910	COG1605	Chorismate mutase
C7N18_RS16915	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C7N18_RS16930	COG2199	diguanylate cyclase activity
C7N18_RS16935	COG2885	chlorophyll binding
C7N18_RS16960	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C7N18_RS16965	COG4137	Cytochrome C assembly protein
C7N18_RS16970	COG4536	flavin adenine dinucleotide binding
C7N18_RS16990	COG0497	DNA recombination
C7N18_RS16995	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C7N18_RS17005	COG2867	negative regulation of translational initiation
C7N18_RS17130	COG0579	oxidoreductase
C7N18_RS17135	COG1012	belongs to the aldehyde dehydrogenase family
C7N18_RS17140	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C7N18_RS17145	COG1113	amino acid transport
C7N18_RS17150	COG1802	Transcriptional regulator
C7N18_RS17155	COG1652	LysM domain
C7N18_RS17160	COG0401	homolog of Blt101
C7N18_RS17165	COG0640	Transcriptional regulator
C7N18_RS17170	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7N18_RS17175	COG2916	Histone family protein nucleoid-structuring protein H-NS
C7N18_RS17190	COG4575	ribosome binding
C7N18_RS17200	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C7N18_RS17210	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C7N18_RS17225	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7N18_RS17235	COG4175	Glycine betaine
C7N18_RS17240	COG4176	ABC-type proline glycine betaine transport system permease component
C7N18_RS17245	COG2113	Glycine betaine
C7N18_RS17250	COG2814	Major facilitator Superfamily
C7N18_RS17255	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
C7N18_RS17265	COG1846	Transcriptional regulator
C7N18_RS17270	COG1566	PFAM secretion protein HlyD family protein
C7N18_RS17275	COG2814	Major facilitator Superfamily
C7N18_RS17300	COG1238	metal cluster binding
C7N18_RS17305	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7N18_RS17335	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
C7N18_RS17355	COG1546	Belongs to the CinA family
C7N18_RS17360	COG2951	lytic endotransglycosylase activity
C7N18_RS17365	COG3730	PTS system glucitol sorbitol-specific
C7N18_RS17370	COG3732	PTS system glucitol sorbitol-specific
C7N18_RS17380	COG1028	Short-chain dehydrogenase reductase Sdr
C7N18_RS17385	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7N18_RS17390	COG1349	DNA-binding transcription factor activity
C7N18_RS17420	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C7N18_RS17425	COG1609	Transcriptional regulator
C7N18_RS17430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7N18_RS17430	COG1263	PTS System
C7N18_RS17435	COG2723	6-phospho-beta-galactosidase activity
C7N18_RS17440	COG5499	transcription regulator containing HTH domain
C7N18_RS17445	COG4680	protein conserved in bacteria
C7N18_RS17455	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C7N18_RS17465	COG3260	NADH ubiquinone oxidoreductase 20
C7N18_RS17470	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C7N18_RS17475	COG3261	NADH dehydrogenase
C7N18_RS17475	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
C7N18_RS17480	COG0650	Formate hydrogenlyase subunit 4
C7N18_RS17485	COG0651	ATP synthesis coupled electron transport
C7N18_RS17490	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C7N18_RS17500	COG0375	protein maturation
C7N18_RS17505	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
C7N18_RS17510	COG0298	carbon dioxide binding
C7N18_RS17515	COG0409	Hydrogenase expression formation protein
C7N18_RS17520	COG0309	Hydrogenase expression formation protein (HypE)
C7N18_RS17525	COG3604	Transcriptional regulator
C7N18_RS17545	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C7N18_RS17560	COG0163	prenyltransferase activity
C7N18_RS17570	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C7N18_RS17575	COG4942	peptidase
C7N18_RS17575	COG1388	LysM domain
C7N18_RS17630	COG2234	aminopeptidase activity
C7N18_RS17635	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C7N18_RS17640	COG1518	maintenance of DNA repeat elements
C7N18_RS17655	COG1857	crispr-associated protein
C7N18_RS17680	COG1203	CRISPR-associated helicase, Cas3
C7N18_RS17705	COG0720	synthase
C7N18_RS17710	COG0644	oxidoreductase
C7N18_RS17715	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C7N18_RS17720	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
C7N18_RS17725	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C7N18_RS17730	COG2086	electron transfer activity
C7N18_RS17735	COG0477	Major facilitator Superfamily
C7N18_RS17740	COG0277	FAD linked oxidase domain protein
C7N18_RS17745	COG1028	Short-chain dehydrogenase reductase Sdr
C7N18_RS17750	COG2223	nitrite transmembrane transporter activity
C7N18_RS17755	COG1070	Carbohydrate kinase
C7N18_RS17760	COG0602	queuosine metabolic process
C7N18_RS17770	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
C7N18_RS17780	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
C7N18_RS17795	COG3956	TIGRFAM MazG family protein
C7N18_RS17800	COG2337	Toxic component of a toxin-antitoxin (TA) module
C7N18_RS17805	COG2336	PFAM SpoVT AbrB
C7N18_RS17810	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C7N18_RS17820	COG2205	protein histidine kinase activity
C7N18_RS17820	COG4999	Histidine kinase
C7N18_RS17820	COG3850	Histidine kinase
C7N18_RS17820	COG3437	response regulator, receiver
C7N18_RS17825	COG4948	Mandelate Racemase Muconate Lactonizing
C7N18_RS17830	COG4948	Mandelate Racemase Muconate Lactonizing
C7N18_RS17835	COG2271	Major facilitator Superfamily
C7N18_RS17840	COG0716	FMN binding
C7N18_RS17845	COG0564	pseudouridine synthase activity
C7N18_RS17850	COG3098	single-species biofilm formation
C7N18_RS17865	COG1611	Belongs to the LOG family
C7N18_RS17870	COG0814	amino acid
C7N18_RS17875	COG1760	l-serine dehydratase
C7N18_RS17885	COG1454	alcohol dehydrogenase
C7N18_RS17890	COG0235	Class ii aldolase
C7N18_RS17895	COG0738	Major facilitator superfamily
C7N18_RS17905	COG1070	Carbohydrate kinase
C7N18_RS17915	COG1349	DNA-binding transcription factor activity
C7N18_RS17925	COG2363	Small membrane protein
C7N18_RS17930	COG0583	DNA-binding transcription factor activity
C7N18_RS17940	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C7N18_RS17945	COG2166	iron-sulfur cluster assembly
C7N18_RS17950	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C7N18_RS17955	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
C7N18_RS17975	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7N18_RS17980	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C7N18_RS17980	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C7N18_RS17985	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C7N18_RS17990	COG1074	ATP-dependent DNA helicase activity
C7N18_RS17995	COG1025	Belongs to the peptidase M16 family
C7N18_RS18000	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
C7N18_RS18005	COG4967	type IV pilus modification protein PilV
C7N18_RS18015	COG4795	General secretion pathway protein
C7N18_RS18020	COG2165	general secretion pathway protein
C7N18_RS18035	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
C7N18_RS18055	COG0861	Integral membrane protein TerC family
C7N18_RS18065	COG0667	Aldo Keto reductase
C7N18_RS18080	COG1609	Transcriptional regulator
C7N18_RS18090	COG0583	DNA-binding transcription factor activity
C7N18_RS18095	COG1794	racemase activity, acting on amino acids and derivatives
C7N18_RS18100	COG2814	Major facilitator Superfamily
C7N18_RS18105	COG1028	Short-chain dehydrogenase reductase Sdr
C7N18_RS18115	COG0183	Belongs to the thiolase family
C7N18_RS18120	COG0814	amino acid
C7N18_RS18125	COG2771	luxR family
C7N18_RS18155	COG2207	Transcriptional regulator
C7N18_RS18165	COG3387	PFAM Glycoside hydrolase 15-related
C7N18_RS18185	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C7N18_RS18190	COG2080	2 iron, 2 sulfur cluster binding
C7N18_RS18195	COG3829	transcription factor binding
C7N18_RS18200	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C7N18_RS18205	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C7N18_RS18210	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7N18_RS18220	COG0549	Belongs to the carbamate kinase family
C7N18_RS18225	COG3608	succinylglutamate desuccinylase aspartoacylase
C7N18_RS18225	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C7N18_RS18230	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C7N18_RS18235	COG2068	MobA-Related Protein
C7N18_RS18240	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C7N18_RS18240	COG0493	'glutamate synthase
C7N18_RS18245	COG0402	S-adenosylhomocysteine deaminase activity
C7N18_RS18250	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C7N18_RS18255	COG2080	2 iron, 2 sulfur cluster binding
C7N18_RS18255	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C7N18_RS18260	COG2233	PERMEase
C7N18_RS18265	COG0402	S-adenosylhomocysteine deaminase activity
C7N18_RS18270	COG2252	PERMEase
C7N18_RS18275	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C7N18_RS18280	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C7N18_RS18280	COG0493	'glutamate synthase
C7N18_RS18285	COG2233	PERMEase
C7N18_RS18305	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C7N18_RS18315	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C7N18_RS18320	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C7N18_RS18325	COG4974	Belongs to the 'phage' integrase family
C7N18_RS18330	COG0716	FMN binding
C7N18_RS18340	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
C7N18_RS18350	COG1272	protein, Hemolysin III
C7N18_RS18360	COG2723	6-phospho-beta-galactosidase activity
C7N18_RS18385	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C7N18_RS18390	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C7N18_RS18395	COG0006	proline dipeptidase activity
C7N18_RS18435	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C7N18_RS18465	COG1024	Enoyl-CoA hydratase
C7N18_RS18470	COG0427	acetyl-CoA hydrolase
C7N18_RS18480	COG2968	Membrane
C7N18_RS18485	COG1279	arginine transmembrane transporter activity
C7N18_RS18555	COG0582	viral genome integration into host DNA
C7N18_RS18570	COG0668	transmembrane transport
C7N18_RS18575	COG0191	fructose-bisphosphate aldolase activity
C7N18_RS18605	COG1122	ATPase activity
C7N18_RS18610	COG1122	ATPase activity
C7N18_RS18615	COG1072	(Pantothenic acid kinase))
C7N18_RS18620	COG3722	fumarate hydratase activity
C7N18_RS18625	COG1494	fructose-1,6-bisphosphatase
C7N18_RS18630	COG1063	alcohol dehydrogenase
C7N18_RS18635	COG2213	PTS system mannitol-specific
C7N18_RS18640	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7N18_RS18650	COG0330	HflC and HflK could
C7N18_RS18655	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C7N18_RS18660	COG0501	Belongs to the peptidase M48B family
C7N18_RS18675	COG1166	arginine decarboxylase activity
C7N18_RS18700	COG2814	Major facilitator Superfamily
C7N18_RS18710	COG2356	endonuclease I
C7N18_RS18715	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C7N18_RS18720	COG0189	ligase activity
C7N18_RS18735	COG2805	Type II/IV secretion system protein
C7N18_RS18740	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C7N18_RS18745	COG0762	integral membrane protein
C7N18_RS18760	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C7N18_RS18770	COG0252	asparaginase activity
C7N18_RS18780	COG3171	Protein conserved in bacteria
C7N18_RS18790	COG1194	a g-specific adenine glycosylase
C7N18_RS18805	COG2211	Major facilitator Superfamily
C7N18_RS18810	COG1982	Orn Lys Arg decarboxylase major
C7N18_RS18815	COG1811	Na channel or pump
C7N18_RS18825	COG0582	viral genome integration into host DNA
C7N18_RS18845	COG3712	iron ion homeostasis
C7N18_RS18850	COG4772	TonB-dependent receptor
C7N18_RS18855	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
C7N18_RS18860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7N18_RS18865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7N18_RS18870	COG1120	ATPase activity
C7N18_RS18875	COG2085	NADP oxidoreductase coenzyme F420-dependent
C7N18_RS18945	COG1620	l-lactate permease
C7N18_RS18950	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C7N18_RS18955	COG3193	protein, possibly involved in utilization of glycolate and propanediol
C7N18_RS18960	COG0247	lactate metabolic process
C7N18_RS18965	COG0277	FAD linked oxidase domain protein
C7N18_RS18970	COG0277	FAD linked oxidase domain protein
C7N18_RS18975	COG2186	Transcriptional regulator
C7N18_RS18985	COG0318	PFAM AMP-dependent synthetase and ligase
C7N18_RS18995	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7N18_RS19000	COG0156	8-amino-7-oxononanoate synthase activity
C7N18_RS19010	COG0795	lipopolysaccharide-transporting ATPase activity
C7N18_RS19015	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
C7N18_RS19025	COG2244	polysaccharide biosynthetic process
C7N18_RS19030	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C7N18_RS19035	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C7N18_RS19040	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C7N18_RS19045	COG0306	phosphate transporter
C7N18_RS19050	COG0754	glutathionylspermidine amidase activity
C7N18_RS19055	COG0625	glutathione transferase activity
C7N18_RS19060	COG0298	carbon dioxide binding
C7N18_RS19070	COG1773	rubredoxin
C7N18_RS19075	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C7N18_RS19080	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
C7N18_RS19085	COG5557	Pfam Polysulphide reductase, NrfD
C7N18_RS19090	COG0437	4 iron, 4 sulfur cluster binding
C7N18_RS19095	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
C7N18_RS19110	COG0667	Aldo Keto reductase
C7N18_RS19120	COG1028	Short-chain dehydrogenase reductase Sdr
C7N18_RS19125	COG0848	biopolymer transport protein
C7N18_RS19130	COG0811	peptide transport
C7N18_RS19135	COG0626	cystathionine gamma-synthase activity
C7N18_RS19140	COG0586	Pfam SNARE associated Golgi protein
C7N18_RS19145	COG2207	Transcriptional regulator
C7N18_RS19150	COG1979	alcohol dehydrogenase
C7N18_RS19155	COG0656	L-ascorbic acid biosynthetic process
C7N18_RS19165	COG4238	major outer membrane lipoprotein
C7N18_RS19170	COG1032	radical SAM domain protein
C7N18_RS19175	COG2132	Multicopper oxidase
C7N18_RS19180	COG0204	Acyl-transferase
C7N18_RS19185	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C7N18_RS19190	COG4166	transmembrane transport
C7N18_RS19195	COG2944	sequence-specific DNA binding
C7N18_RS19205	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
C7N18_RS19210	COG3111	PFAM Bacterial OB fold (BOF) protein
C7N18_RS19215	COG0745	RESPONSE REGULATOR receiver
C7N18_RS19220	COG0642	Histidine kinase
C7N18_RS19230	COG2249	NAD(P)H dehydrogenase (quinone) activity
C7N18_RS19235	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C7N18_RS19250	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C7N18_RS19255	COG3151	Protein conserved in bacteria
C7N18_RS19265	COG1538	Outer membrane efflux protein
C7N18_RS19275	COG0754	glutathionylspermidine amidase activity
C7N18_RS19280	COG3384	dioxygenase
C7N18_RS19310	COG2268	Band 7 protein
C7N18_RS19335	COG3025	triphosphatase activity
C7N18_RS19340	COG4991	sh3 domain protein
C7N18_RS19355	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C7N18_RS19365	COG0583	DNA-binding transcription factor activity
C7N18_RS19370	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C7N18_RS19375	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C7N18_RS19380	COG0471	metal ion transport
C7N18_RS19390	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C7N18_RS19400	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C7N18_RS19415	COG2375	cellular response to nickel ion
C7N18_RS19420	COG1695	Transcriptional regulator
C7N18_RS19425	COG0840	transmembrane signaling receptor activity
C7N18_RS19435	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7N18_RS19440	COG1609	Transcriptional regulator
C7N18_RS19445	COG3250	beta-galactosidase activity
C7N18_RS19450	COG2731	YhcH YjgK YiaL family protein
C7N18_RS19455	COG0531	amino acid
C7N18_RS19465	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
C7N18_RS19465	COG3408	Glycogen debranching enzyme
C7N18_RS19475	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7N18_RS19475	COG1902	pentaerythritol trinitrate reductase activity
C7N18_RS19480	COG5499	transcription regulator containing HTH domain
C7N18_RS19485	COG4680	protein conserved in bacteria
C7N18_RS19495	COG1451	nucleotide metabolic process
C7N18_RS19500	COG2949	membrane
C7N18_RS19505	COG0673	inositol 2-dehydrogenase activity
C7N18_RS19510	COG0861	Integral membrane protein TerC family
C7N18_RS19530	COG2721	sulfolactate sulfo-lyase activity
C7N18_RS19540	COG2271	Major facilitator Superfamily
C7N18_RS19545	COG2186	Transcriptional regulator
C7N18_RS19550	COG0586	Pfam SNARE associated Golgi protein
C7N18_RS19560	COG1422	Protein of unknown function (DUF1090)
C7N18_RS19565	COG4575	ribosome binding
C7N18_RS19570	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
C7N18_RS19580	COG2259	Doxx family
C7N18_RS19585	COG0435	Glutathione S-transferase
C7N18_RS19590	COG3152	Membrane
C7N18_RS19595	COG3152	Membrane
C7N18_RS19600	COG0583	DNA-binding transcription factor activity
C7N18_RS19605	COG1741	Belongs to the pirin family
C7N18_RS19620	COG0814	amino acid
C7N18_RS19625	COG1760	l-serine dehydratase
C7N18_RS19630	COG0251	oxidation-reduction process
C7N18_RS19635	COG1882	Formate acetyltransferase
C7N18_RS19640	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C7N18_RS19650	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C7N18_RS19655	COG0583	DNA-binding transcription factor activity
C7N18_RS19680	COG1929	Belongs to the glycerate kinase type-1 family
C7N18_RS19685	COG2084	Dehydrogenase
C7N18_RS19700	COG2721	sulfolactate sulfo-lyase activity
C7N18_RS19705	COG2002	toxin-antitoxin pair type II binding
C7N18_RS19715	COG1349	DNA-binding transcription factor activity
C7N18_RS19725	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7N18_RS19735	COG3716	PTS system mannose fructose sorbose family IID component
C7N18_RS19740	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7N18_RS19745	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C7N18_RS19750	COG2222	sugar isomerase
C7N18_RS19760	COG1263	PTS System
C7N18_RS19760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7N18_RS19765	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C7N18_RS19785	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C7N18_RS19805	COG2823	Periplasmic or secreted lipoprotein
C7N18_RS19810	COG0701	Predicted permease
C7N18_RS19815	COG0702	epimerase
C7N18_RS19820	COG0693	protein deglycase activity
C7N18_RS19835	COG3153	acetyltransferase
C7N18_RS19840	COG3154	lipid carrier protein
C7N18_RS19845	COG0826	peptidase U32
C7N18_RS19850	COG0826	peptidase U32
C7N18_RS19855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7N18_RS19865	COG0513	Belongs to the DEAD box helicase family
C7N18_RS19905	COG0195	Participates in both transcription termination and antitermination
C7N18_RS19935	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C7N18_RS19945	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C7N18_RS19950	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C7N18_RS19960	COG1534	Rna-binding protein
C7N18_RS19965	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C7N18_RS19980	COG0697	spore germination
C7N18_RS19995	COG0142	geranyltranstransferase activity
C7N18_RS20000	COG3423	Transcriptional regulator
C7N18_RS20010	COG5007	Belongs to the BolA IbaG family
C7N18_RS20020	COG2854	intermembrane phospholipid transfer
C7N18_RS20025	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C7N18_RS20030	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C7N18_RS20035	COG1127	ABC transporter
C7N18_RS20040	COG0530	calcium, potassium:sodium antiporter activity
C7N18_RS20045	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C7N18_RS20045	COG0517	IMP dehydrogenase activity
C7N18_RS20050	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
C7N18_RS20055	COG3117	lipopolysaccharide transmembrane transporter activity
C7N18_RS20060	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
C7N18_RS20065	COG1137	ATPase activity
C7N18_RS20070	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C7N18_RS20075	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C7N18_RS20090	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7N18_RS20095	COG0515	serine threonine protein kinase
C7N18_RS20110	COG5002	protein histidine kinase activity
C7N18_RS20110	COG0784	Response regulator, receiver
C7N18_RS20110	COG2198	Histidine kinase
C7N18_RS20115	COG1242	4 iron, 4 sulfur cluster binding
C7N18_RS20120	COG0070	glutamate synthase
C7N18_RS20120	COG0069	glutamate synthase activity
C7N18_RS20120	COG0067	glutamate synthase
C7N18_RS20125	COG0493	'glutamate synthase
C7N18_RS20130	COG4804	nuclease activity
C7N18_RS20135	COG2731	YhcH YjgK YiaL family protein
C7N18_RS20165	COG3069	C4-dicarboxylate transmembrane transporter activity
C7N18_RS20170	COG2969	positive regulation of protein catabolic process
C7N18_RS20175	COG0625	glutathione transferase activity
C7N18_RS20195	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
C7N18_RS20200	COG3105	Protein conserved in bacteria
C7N18_RS20205	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7N18_RS20210	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7N18_RS20250	COG0583	DNA-binding transcription factor activity
C7N18_RS20255	COG0312	modulator of DNA gyrase
C7N18_RS20260	COG3164	Protein of unknown function
C7N18_RS20265	COG1530	ribonuclease E activity
C7N18_RS20270	COG0424	maF-like protein
C7N18_RS20275	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C7N18_RS20280	COG1792	Involved in formation and maintenance of cell shape
C7N18_RS20285	COG1077	Cell shape determining protein MreB Mrl
C7N18_RS20295	COG2199	diguanylate cyclase activity
C7N18_RS20295	COG2200	EAL domain
C7N18_RS20300	COG0604	alcohol dehydrogenase
C7N18_RS20310	COG0511	ligase activity, forming carbon-carbon bonds
C7N18_RS20315	COG0439	Biotin carboxylase
C7N18_RS20320	COG3924	membrane
C7N18_RS20325	COG4145	pantothenate transmembrane transporter activity
C7N18_RS20335	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7N18_RS20345	COG2189	Belongs to the N(4) N(6)-methyltransferase family
C7N18_RS20355	COG1309	transcriptional regulator
C7N18_RS20360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7N18_RS20370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7N18_RS20375	COG4597	amino acid ABC transporter
C7N18_RS20380	COG0765	amino acid transport
C7N18_RS20385	COG1126	abc transporter atp-binding protein
C7N18_RS20425	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C7N18_RS20440	COG0009	L-threonylcarbamoyladenylate synthase
C7N18_RS20445	COG0551	DNA topoisomerase type I activity
C7N18_RS20455	COG0758	DNA mediated transformation
C7N18_RS20475	COG0569	domain protein
C7N18_RS20485	COG3036	rescue of stalled ribosome
C7N18_RS20490	COG0789	Transcriptional regulator
C7N18_RS20530	COG0201	protein transport
C7N18_RS20620	COG0089	rRNA binding
C7N18_RS20695	COG2964	Protein conserved in bacteria
C7N18_RS20700	COG0545	Peptidyl-prolyl cis-trans isomerase
C7N18_RS20710	COG1047	Peptidyl-prolyl cis-trans
C7N18_RS20715	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
C7N18_RS20730	COG0488	(ABC) transporter
C7N18_RS20745	COG3954	Phosphoribulokinase
C7N18_RS20750	COG1765	OsmC-like protein
C7N18_RS20755	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7N18_RS20760	COG1289	transmembrane transporter activity
C7N18_RS20765	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C7N18_RS20770	COG0512	Glutamine amidotransferase of anthranilate synthase
C7N18_RS20775	COG2184	nucleotidyltransferase activity
C7N18_RS20785	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C7N18_RS20800	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7N18_RS20805	COG2146	nitrite reductase [NAD(P)H] activity
C7N18_RS20810	COG2116	formate transmembrane transporter activity
C7N18_RS20825	COG0626	cystathionine gamma-synthase activity
C7N18_RS20840	COG1735	metal-dependent hydrolase with the TIM-barrel fold
C7N18_RS20845	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
C7N18_RS20850	COG3457	Alanine racemase
C7N18_RS20860	COG2188	Transcriptional regulator
C7N18_RS20865	COG0180	Tryptophanyl-tRNA synthetase
C7N18_RS20870	COG0546	phosphoglycolate phosphatase activity
C7N18_RS20875	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C7N18_RS20880	COG0338	D12 class N6 adenine-specific DNA methyltransferase
C7N18_RS20885	COG3266	domain, Protein
C7N18_RS20900	COG4796	Type ii and iii secretion system protein
C7N18_RS20915	COG3166	PFAM Fimbrial assembly family protein
C7N18_RS20920	COG4972	Pilus assembly protein
C7N18_RS20925	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
C7N18_RS20930	COG0494	nUDIX hydrolase
C7N18_RS20940	COG1011	Hydrolase
C7N18_RS20945	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C7N18_RS20955	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
C7N18_RS20975	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C7N18_RS20980	COG2183	response to ionizing radiation
C7N18_RS20985	COG1918	ferrous iron import across plasma membrane
C7N18_RS20990	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
C7N18_RS21000	COG5464	transposase or invertase
C7N18_RS21020	COG1040	competence protein
C7N18_RS21030	COG2610	gluconate transmembrane transporter activity
C7N18_RS21035	COG1640	4-alpha-glucanotransferase
C7N18_RS21040	COG0058	SHG alpha-glucan phosphorylase activity
C7N18_RS21065	COG1690	Belongs to the RtcB family
C7N18_RS21070	COG4650	regulator
C7N18_RS21075	COG1349	DNA-binding transcription factor activity
C7N18_RS21090	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C7N18_RS21110	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C7N18_RS21115	COG0058	SHG alpha-glucan phosphorylase activity
C7N18_RS21135	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
C7N18_RS21140	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C7N18_RS21145	COG2095	MarC family integral membrane protein
C7N18_RS21150	COG2610	gluconate transmembrane transporter activity
C7N18_RS21155	COG3265	gluconokinase activity
C7N18_RS21160	COG1609	Transcriptional regulator
C7N18_RS21165	COG1741	Belongs to the pirin family
C7N18_RS21170	COG0673	inositol 2-dehydrogenase activity
C7N18_RS21175	COG1247	-acetyltransferase
C7N18_RS21180	COG3157	Type VI secretion system effector, Hcp
C7N18_RS21210	COG0405	Gamma-glutamyltransferase
C7N18_RS21220	COG0584	glycerophosphoryl diester phosphodiesterase
C7N18_RS21235	COG1175	transmembrane transport
C7N18_RS21240	COG1653	transport
C7N18_RS21250	COG0410	ABC transporter
C7N18_RS21255	COG0411	ABC transporter
C7N18_RS21260	COG4177	L-phenylalanine transmembrane transporter activity
C7N18_RS21265	COG0559	Belongs to the binding-protein-dependent transport system permease family
C7N18_RS21270	COG0683	leucine binding
C7N18_RS21275	COG0456	acetyltransferase
C7N18_RS21290	COG0683	leucine binding
C7N18_RS21295	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C7N18_RS21300	COG2177	Part of the ABC transporter FtsEX involved in
C7N18_RS21305	COG2884	Cell division ATP-binding protein ftsE
C7N18_RS21310	COG0552	protein localization to endoplasmic reticulum
C7N18_RS21315	COG0742	ribosomal rna small subunit methyltransferase
C7N18_RS21320	COG3776	membrane
C7N18_RS21330	COG3714	YhhN family
C7N18_RS21350	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C7N18_RS21365	COG0628	permease
C7N18_RS21385	COG0204	Acyl-transferase
C7N18_RS21395	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7N18_RS21415	COG1216	Glycosyl transferase, family 2
C7N18_RS21440	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C7N18_RS21450	COG1028	Short-chain dehydrogenase reductase Sdr
C7N18_RS21455	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C7N18_RS21460	COG2091	lysine biosynthetic process via aminoadipic acid
C7N18_RS21465	COG0747	negative chemotaxis
C7N18_RS21470	COG0601	transmembrane transport
C7N18_RS21475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7N18_RS21480	COG0444	Belongs to the ABC transporter superfamily
C7N18_RS21495	COG2188	Transcriptional regulator
C7N18_RS21505	COG3414	Phosphotransferase system galactitol-specific IIB component
C7N18_RS21510	COG3775	system Galactitol-specific IIC component
C7N18_RS21525	COG0191	fructose-bisphosphate aldolase activity
C7N18_RS21540	COG0842	Transport permease protein
C7N18_RS21545	COG1129	ABC transporter
C7N18_RS21545	COG0842	Transport permease protein
C7N18_RS21550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7N18_RS21570	COG2081	HI0933 family
C7N18_RS21575	COG0306	phosphate transporter
C7N18_RS21585	COG0589	response to stress
C7N18_RS21595	COG3104	oligopeptide transport
C7N18_RS21605	COG0339	signal peptide processing
C7N18_RS21610	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
C7N18_RS21615	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7N18_RS21625	COG1393	Belongs to the ArsC family
C7N18_RS21635	COG3065	identical protein binding
C7N18_RS21640	COG2197	response regulator
C7N18_RS21645	COG3720	iron ion transport
C7N18_RS21650	COG4771	TonB-dependent receptor
C7N18_RS21660	COG4558	Periplasmic binding protein
C7N18_RS21670	COG3721	Heme iron utilization protein
C7N18_RS21680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7N18_RS21690	COG1285	pathogenesis
C7N18_RS21705	COG3247	response to pH
C7N18_RS21710	COG2771	luxR family
C7N18_RS21720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7N18_RS21725	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C7N18_RS21730	COG2207	Transcriptional regulator
C7N18_RS21735	COG2207	Transcriptional regulator
C7N18_RS21740	COG0076	glutamate decarboxylase activity
C7N18_RS21760	COG0583	DNA-binding transcription factor activity
C7N18_RS21765	COG1295	ribonuclease BN
C7N18_RS21770	COG0477	Major facilitator Superfamily
C7N18_RS21775	COG2982	Protein involved in outer membrane biogenesis
C7N18_RS21780	COG2200	EAL domain
C7N18_RS21790	COG0612	Peptidase, M16
C7N18_RS21800	COG2200	EAL domain
C7N18_RS21800	COG2199	diguanylate cyclase activity
C7N18_RS21805	COG0457	Tetratricopeptide repeat
C7N18_RS21805	COG3118	belongs to the thioredoxin family
C7N18_RS21810	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
C7N18_RS21815	COG1215	transferase activity, transferring glycosyl groups
C7N18_RS21820	COG1215	transferase activity, transferring glycosyl groups
C7N18_RS21840	COG2194	sulfuric ester hydrolase activity
C7N18_RS21850	COG0814	amino acid
C7N18_RS21855	COG4608	Belongs to the ABC transporter superfamily
C7N18_RS21860	COG0444	Belongs to the ABC transporter superfamily
C7N18_RS21865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7N18_RS21870	COG0601	transmembrane transport
C7N18_RS21880	COG0747	negative chemotaxis
C7N18_RS21890	COG2194	sulfuric ester hydrolase activity
C7N18_RS21895	COG3539	Fimbrial protein
C7N18_RS21900	COG3539	Fimbrial protein
C7N18_RS21910	COG3121	Chaperone
C7N18_RS21915	COG3539	Fimbrial protein
C7N18_RS21925	COG5571	outer membrane autotransporter
C7N18_RS21930	COG2818	Glycosylase
C7N18_RS21935	COG0456	acetyltransferase
C7N18_RS21940	COG0243	molybdopterin cofactor binding
C7N18_RS21945	COG2885	chlorophyll binding
C7N18_RS21960	COG2944	sequence-specific DNA binding
C7N18_RS21965	COG1278	Cold shock
C7N18_RS21990	COG3274	enterobacterial common antigen metabolic process
C7N18_RS21995	COG4682	membrane
C7N18_RS22000	COG4682	membrane
C7N18_RS22015	COG4213	ABC transporter substrate-binding protein
C7N18_RS22030	COG1609	Transcriptional regulator
C7N18_RS22030	COG2207	Transcriptional regulator
C7N18_RS22035	COG2992	FlgJ-related protein
C7N18_RS22040	COG0366	Alpha amylase catalytic
C7N18_RS22045	COG3977	Valine--pyruvate aminotransferase
C7N18_RS22050	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C7N18_RS22055	COG1414	Transcriptional regulator
C7N18_RS22075	COG3713	MltA-interacting MipA family protein
C7N18_RS22080	COG0583	DNA-binding transcription factor activity
C7N18_RS22085	COG1566	PFAM secretion protein HlyD family protein
C7N18_RS22100	COG1012	belongs to the aldehyde dehydrogenase family
C7N18_RS22110	COG1454	alcohol dehydrogenase
C7N18_RS22115	COG3276	selenocysteine insertion sequence binding
C7N18_RS22125	COG0625	glutathione transferase activity
C7N18_RS22130	COG1566	PFAM secretion protein HlyD family protein
C7N18_RS22140	COG2213	PTS system mannitol-specific
C7N18_RS22140	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7N18_RS22150	COG3722	fumarate hydratase activity
C7N18_RS22170	COG5295	Hep Hag repeat protein
C7N18_RS22175	COG1620	l-lactate permease
C7N18_RS22180	COG2186	Transcriptional regulator
C7N18_RS22190	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C7N18_RS22195	COG1045	serine acetyltransferase
C7N18_RS22210	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C7N18_RS22215	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7N18_RS22230	COG4942	peptidase
C7N18_RS22235	COG2861	carbohydrate metabolic process
C7N18_RS22240	COG1216	Glycosyl transferase, family 2
C7N18_RS22250	COG0156	8-amino-7-oxononanoate synthase activity
C7N18_RS22260	COG0859	PFAM glycosyl transferase family 9
C7N18_RS22265	COG0859	PFAM glycosyl transferase family 9
C7N18_RS22270	COG3307	-O-antigen
C7N18_RS22275	COG1216	Glycosyl transferase, family 2
C7N18_RS22280	COG1442	glycosyl transferase family 8
C7N18_RS22285	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C7N18_RS22300	COG0515	serine threonine protein kinase
C7N18_RS22305	COG0438	transferase activity, transferring glycosyl groups
C7N18_RS22310	COG0859	PFAM glycosyl transferase family 9
C7N18_RS22315	COG1519	Transferase
C7N18_RS22345	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C7N18_RS22370	COG1561	YicC-like family, N-terminal region
C7N18_RS22380	COG2860	membrane
C7N18_RS22390	COG0194	GDP metabolic process
C7N18_RS22400	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C7N18_RS22405	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7N18_RS22410	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C7N18_RS22420	COG0786	glutamate:sodium symporter activity
C7N18_RS22425	COG2233	PERMEase
C7N18_RS22430	COG2982	Protein involved in outer membrane biogenesis
C7N18_RS22435	COG1501	Belongs to the glycosyl hydrolase 31 family
C7N18_RS22440	COG2211	Major facilitator Superfamily
C7N18_RS22450	COG0582	viral genome integration into host DNA
C7N18_RS22570	COG5492	domain, Protein
C7N18_RS22740	COG0697	spore germination
C7N18_RS22745	COG1464	Belongs to the NlpA lipoprotein family
C7N18_RS22755	COG2814	Major facilitator Superfamily
C7N18_RS22790	COG2271	Major facilitator Superfamily
C7N18_RS22795	COG2271	Major facilitator Superfamily
C7N18_RS22800	COG3851	Histidine kinase
C7N18_RS22805	COG2197	response regulator
C7N18_RS22825	COG0440	acetolactate synthase activity
C7N18_RS22830	COG0028	Belongs to the TPP enzyme family
C7N18_RS22845	COG2814	Major facilitator Superfamily
C7N18_RS22850	COG0641	radical SAM
C7N18_RS22860	COG2149	membrane
C7N18_RS22870	COG3119	arylsulfatase activity
C7N18_RS22875	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7N18_RS22880	COG2207	Transcriptional regulator
C7N18_RS22895	COG2188	Transcriptional regulator
C7N18_RS22915	COG5645	(Lipo)protein
C7N18_RS22920	COG0823	Involved in the tonB-independent uptake of proteins
C7N18_RS22935	COG0561	phosphatase activity
C7N18_RS22940	COG3753	Protein conserved in bacteria
C7N18_RS22945	COG0187	DNA topoisomerase II activity
C7N18_RS22955	COG0592	DNA-directed DNA polymerase activity
C7N18_RS23005	COG0814	amino acid
C7N18_RS23020	COG2091	lysine biosynthetic process via aminoadipic acid
C7N18_RS23025	COG0431	NADPH-dependent FMN reductase
C7N18_RS23030	COG2252	PERMEase
C7N18_RS23035	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7N18_RS23070	COG0704	Plays a role in the regulation of phosphate uptake
C7N18_RS23075	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7N18_RS23080	COG0581	inorganic phosphate transmembrane transporter activity
C7N18_RS23085	COG0573	inorganic phosphate transmembrane transporter activity
C7N18_RS23090	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C7N18_RS23095	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C7N18_RS23145	COG3312	ion transport
C7N18_RS23160	COG0716	FMN binding
C7N18_RS23165	COG1522	sequence-specific DNA binding
C7N18_RS23195	COG1129	ABC transporter
C7N18_RS23200	COG1172	Belongs to the binding-protein-dependent transport system permease family
C7N18_RS23205	COG1879	ABC-type sugar transport system periplasmic component
C7N18_RS23210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7N18_RS23220	COG0477	Major facilitator Superfamily
C7N18_RS23225	COG2186	Transcriptional regulator
C7N18_RS23265	COG3085	chromosome segregation
C7N18_RS23270	COG0606	chelatase, subunit chli
C7N18_RS23290	COG3978	acetolactate synthase activity
C7N18_RS23295	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7N18_RS23305	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C7N18_RS23310	COG0583	DNA-binding transcription factor activity
C7N18_RS23320	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C7N18_RS23325	COG3692	DNA binding
C7N18_RS23330	COG0210	DNA helicase
C7N18_RS23345	COG3118	belongs to the thioredoxin family
C7N18_RS23355	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C7N18_RS23370	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C7N18_RS23375	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
C7N18_RS23380	COG1088	dTDP-glucose 4,6-dehydratase activity
C7N18_RS23385	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C7N18_RS23390	COG0456	acetyltransferase
C7N18_RS23395	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C7N18_RS23400	COG2244	polysaccharide biosynthetic process
C7N18_RS23445	COG0641	radical SAM
C7N18_RS23450	COG3119	arylsulfatase activity
C7N18_RS23455	COG3071	HemY protein
C7N18_RS23460	COG2959	enzyme of heme biosynthesis
C7N18_RS23465	COG1587	Uroporphyrinogen-III synthase
C7N18_RS23495	COG5567	small periplasmic lipoprotein
C7N18_RS23505	COG3159	Protein conserved in bacteria
C7N18_RS23520	COG0210	DNA helicase
C7N18_RS23525	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
C7N18_RS23530	COG3698	Phosphodiester glycosidase
C7N18_RS23535	COG0598	Magnesium transport protein CorA
C7N18_RS23565	COG2962	Rard protein
C7N18_RS23570	COG2050	protein possibly involved in aromatic compounds catabolism
C7N18_RS23575	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
C7N18_RS23580	COG0514	ATP-dependent DNA helicase (RecQ)
C7N18_RS23585	COG1280	lysine exporter protein (LysE YggA)
C7N18_RS23590	COG1280	lysine exporter protein (LysE YggA)
C7N18_RS23595	COG2267	carboxylic ester hydrolase activity
C7N18_RS23600	COG0561	phosphatase activity
C7N18_RS23605	COG0697	spore germination
C7N18_RS23610	COG0583	DNA-binding transcription factor activity
C7N18_RS23645	COG0412	Dienelactone hydrolase
C7N18_RS23650	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
C7N18_RS23655	COG1322	Protein conserved in bacteria
C7N18_RS23665	COG3165	ubiquinone biosynthetic process from chorismate
C7N18_RS23675	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C7N18_RS23680	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C7N18_RS23685	COG0805	protein transport
C7N18_RS23695	COG0250	Participates in transcription elongation, termination and antitermination
C7N18_RS23700	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C7N18_RS23705	COG0543	2 iron, 2 sulfur cluster binding
C7N18_RS23725	COG1739	Uncharacterized protein family UPF0029
C7N18_RS23730	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C7N18_RS23735	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
C7N18_RS23765	COG1763	Mo-molybdopterin cofactor biosynthetic process
C7N18_RS23770	COG0746	molybdenum cofactor guanylyltransferase activity
C7N18_RS23775	COG3084	Protein conserved in bacteria
C7N18_RS23780	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C7N18_RS23785	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C7N18_RS23790	COG5339	Protein conserved in bacteria
C7N18_RS23795	COG0204	Acyl-transferase
C7N18_RS23805	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7N18_RS23805	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7N18_RS23815	COG3078	GTPase activator activity
C7N18_RS23820	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C7N18_RS23830	COG2204	response regulator
C7N18_RS23835	COG3852	Histidine kinase
C7N18_RS23840	COG0174	glutamine synthetase
C7N18_RS23845	COG1217	gtp-binding protein TYPA
C7N18_RS23850	COG2188	Transcriptional regulator
C7N18_RS23855	COG1082	Xylose isomerase domain protein TIM barrel
C7N18_RS23860	COG2271	Major facilitator Superfamily
C7N18_RS23875	COG1011	Hydrolase
C7N18_RS23905	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C7N18_RS23910	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C7N18_RS23925	COG2864	formate dehydrogenase
C7N18_RS23930	COG0437	4 iron, 4 sulfur cluster binding
C7N18_RS23950	COG3711	transcriptional antiterminator
C7N18_RS23950	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7N18_RS23955	COG1363	Peptidase, m42
C7N18_RS23960	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7N18_RS23960	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7N18_RS23965	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7N18_RS24000	COG1917	Cupin 2, conserved barrel domain protein
C7N18_RS24000	COG4977	sequence-specific DNA binding
C7N18_RS24010	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C7N18_RS24020	COG2258	MOSC domain
C7N18_RS24025	COG2205	protein histidine kinase activity
C7N18_RS24030	COG0745	RESPONSE REGULATOR receiver
C7N18_RS24035	COG3678	ATP-independent chaperone mediated protein folding
C7N18_RS24110	COG4695	Portal protein
C7N18_RS24205	COG5301	cellulose 1,4-beta-cellobiosidase activity
C7N18_RS24270	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C7N18_RS24290	COG3152	Membrane
C7N18_RS24295	COG3691	Protein conserved in bacteria
C7N18_RS24300	COG0589	response to stress
C7N18_RS24310	COG1494	fructose-1,6-bisphosphatase
C7N18_RS24320	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C7N18_RS24345	COG1575	Belongs to the MenA family. Type 1 subfamily
C7N18_RS24360	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C7N18_RS24365	COG1609	Transcriptional regulator
C7N18_RS24370	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C7N18_RS24380	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
C7N18_RS24390	COG0626	cystathionine gamma-synthase activity
C7N18_RS24395	COG0527	aspartate kinase activity
C7N18_RS24395	COG0460	homoserine dehydrogenase
C7N18_RS24405	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C7N18_RS24415	COG0697	spore germination
C7N18_RS24420	COG3738	Protein conserved in bacteria
C7N18_RS24425	COG0371	Dehydrogenase
C7N18_RS24430	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C7N18_RS24435	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7N18_RS24435	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7N18_RS24435	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C7N18_RS24440	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7N18_RS24445	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7N18_RS24450	COG1882	Formate acetyltransferase
C7N18_RS24455	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C7N18_RS24460	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7N18_RS24465	COG2207	Transcriptional regulator
C7N18_RS24470	COG2194	sulfuric ester hydrolase activity
C7N18_RS24500	COG0583	DNA-binding transcription factor activity
C7N18_RS24510	COG1473	amidohydrolase
C7N18_RS24515	COG0477	Major facilitator Superfamily
C7N18_RS24520	COG1309	transcriptional regulator
C7N18_RS24530	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C7N18_RS24535	COG4206	TonB-dependent receptor
C7N18_RS24540	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C7N18_RS24565	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C7N18_RS24570	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
C7N18_RS24570	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
C7N18_RS24605	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C7N18_RS24610	COG0250	Participates in transcription elongation, termination and antitermination
C7N18_RS24650	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
C7N18_RS24660	COG2104	thiamine diphosphate biosynthetic process
C7N18_RS24665	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C7N18_RS24700	COG3068	Protein conserved in bacteria
C7N18_RS24715	COG3678	ATP-independent chaperone mediated protein folding
C7N18_RS24720	COG4191	Histidine kinase
C7N18_RS24725	COG2204	response regulator
C7N18_RS24730	COG0151	Belongs to the GarS family
C7N18_RS24760	COG0456	acetyltransferase
C7N18_RS24770	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C7N18_RS24775	COG2224	Isocitrate lyase
C7N18_RS24790	COG1414	Transcriptional regulator
C7N18_RS24795	COG0646	methionine synthase
C7N18_RS24795	COG1410	methionine synthase
C7N18_RS24800	COG1283	sodium-dependent phosphate transmembrane transporter activity
C7N18_RS24845	COG1187	pseudouridine synthase activity
C7N18_RS24860	COG3541	Predicted nucleotidyltransferase
C7N18_RS24870	COG0527	aspartate kinase activity
C7N18_RS24900	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C7N18_RS24915	COG0477	Major facilitator Superfamily
C7N18_RS24915	COG2814	Major facilitator Superfamily
C7N18_RS24920	COG3833	ABC-type maltose transport systems, permease component
C7N18_RS24925	COG1175	transmembrane transport
C7N18_RS24930	COG2182	Extracellular solute-binding protein
C7N18_RS24935	COG3842	ATPase activity
C7N18_RS24950	COG1357	PFAM Pentapeptide repeats (8 copies)
C7N18_RS24970	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C7N18_RS24980	COG0534	Mate efflux family protein
C7N18_RS24985	COG3237	CsbD-like
C7N18_RS24990	COG0735	belongs to the Fur family
C7N18_RS25005	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7N18_RS25015	COG0604	alcohol dehydrogenase
C7N18_RS25020	COG0305	Participates in initiation and elongation during chromosome replication
C7N18_RS25025	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C7N18_RS25030	COG1448	Aminotransferase
C7N18_RS25040	COG3700	Belongs to the class B bacterial acid phosphatase family
C7N18_RS25045	COG0432	Pfam Uncharacterised protein family UPF0047
C7N18_RS25050	COG2315	Protein conserved in bacteria
C7N18_RS25055	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C7N18_RS25060	COG0629	single-stranded DNA binding
C7N18_RS25070	COG4943	cyclic-guanylate-specific phosphodiesterase activity
C7N18_RS25075	COG2207	Transcriptional regulator
C7N18_RS25080	COG0789	Transcriptional regulator
C7N18_RS25085	COG2252	PERMEase
C7N18_RS25090	COG0025	NhaP-type Na H and K H
C7N18_RS25095	COG1357	PFAM Pentapeptide repeats (8 copies)
C7N18_RS25105	COG3162	membrane
C7N18_RS25110	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C7N18_RS25120	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
C7N18_RS25125	COG0437	4 iron, 4 sulfur cluster binding
C7N18_RS25130	COG3301	Polysulphide reductase, NrfD
C7N18_RS25140	COG3088	subunit of a heme lyase
C7N18_RS25145	COG4235	cytochrome complex assembly
C7N18_RS25150	COG1301	dicarboxylic acid transport
C7N18_RS25155	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C7N18_RS25170	COG1289	transmembrane transporter activity
C7N18_RS25175	COG1566	PFAM secretion protein HlyD family protein
C7N18_RS25185	COG2015	COG2015, Alkyl sulfatase and related hydrolases
C7N18_RS25195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7N18_RS25215	COG1172	Belongs to the binding-protein-dependent transport system permease family
C7N18_RS25220	COG1129	ABC transporter
C7N18_RS25245	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C7N18_RS25250	COG0456	acetyltransferase
C7N18_RS25255	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
C7N18_RS25260	COG3454	Phosphonate metabolism
C7N18_RS25265	COG4778	phosphonate C-P lyase system protein PhnL
C7N18_RS25270	COG4107	phosphonate C-P lyase system protein PhnK
C7N18_RS25275	COG3627	carbon phosphorus lyase activity
C7N18_RS25280	COG3626	phosphonate metabolism
C7N18_RS25285	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
C7N18_RS25290	COG3624	Phosphonate C-P lyase system protein PhnG
C7N18_RS25295	COG2188	Transcriptional regulator
C7N18_RS25300	COG3639	organic phosphonate transmembrane transporter activity
C7N18_RS25305	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
C7N18_RS25310	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
C7N18_RS25315	COG2764	glyoxalase bleomycin resistance protein dioxygenase
C7N18_RS25320	COG2824	Alkylphosphonate utilization operon protein PhnA
C7N18_RS25325	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C7N18_RS25335	COG0477	Major facilitator Superfamily
C7N18_RS25345	COG0642	Histidine kinase
C7N18_RS25350	COG0745	RESPONSE REGULATOR receiver
C7N18_RS25355	COG2194	sulfuric ester hydrolase activity
C7N18_RS25360	COG0531	amino acid
C7N18_RS25365	COG2207	Transcriptional regulator
C7N18_RS25370	COG1982	Orn Lys Arg decarboxylase major
C7N18_RS25375	COG2169	Transcriptional regulator
C7N18_RS25380	COG1486	melibiose metabolic process
C7N18_RS25395	COG2211	Major facilitator Superfamily
C7N18_RS25405	COG3647	Membrane
C7N18_RS25410	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C7N18_RS25410	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C7N18_RS25415	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C7N18_RS25425	COG4565	transcriptional regulatory protein
C7N18_RS25430	COG3290	protein histidine kinase activity
C7N18_RS25435	COG3592	Divergent 4Fe-4S mono-cluster
C7N18_RS25440	COG2388	GCN5-related N-acetyl-transferase
C7N18_RS25465	COG1982	Orn Lys Arg decarboxylase major
C7N18_RS25470	COG0531	amino acid
C7N18_RS25475	COG3710	Transcriptional regulator
C7N18_RS25505	COG4983	Phage plasmid primase, P4 family domain protein
C7N18_RS25575	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C7N18_RS25580	COG0625	glutathione transferase activity
C7N18_RS25595	COG2271	Major facilitator Superfamily
C7N18_RS25680	COG4372	Transposase
C7N18_RS25685	COG0582	viral genome integration into host DNA
C7N18_RS25695	COG1309	transcriptional regulator
C7N18_RS25700	COG4232	protein-disulfide reductase activity
C7N18_RS25710	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C7N18_RS25715	COG1027	Aspartate ammonia-lyase
C7N18_RS25720	COG3030	protein affecting phage T7 exclusion by the F plasmid
C7N18_RS25725	COG0531	amino acid
C7N18_RS25750	COG1509	lysine 2,3-aminomutase activity
C7N18_RS25760	COG5510	response to toxic substance
C7N18_RS25765	COG5510	response to toxic substance
C7N18_RS25770	COG2076	Multidrug Resistance protein
C7N18_RS25775	COG3040	lipid binding
C7N18_RS25795	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C7N18_RS25800	COG1053	succinate dehydrogenase
C7N18_RS25810	COG0531	amino acid
C7N18_RS25815	COG1511	domain protein
C7N18_RS25815	COG3264	Mechanosensitive ion channel
C7N18_RS25865	COG0802	atpase or kinase
C7N18_RS25870	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7N18_RS25890	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C7N18_RS25895	COG0330	HflC and HflK could
C7N18_RS25900	COG0330	HflC and HflK could
C7N18_RS25905	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
C7N18_RS25920	COG0557	exoribonuclease II activity
C7N18_RS25925	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7N18_RS25930	COG3789	protein conserved in bacteria
C7N18_RS25935	COG1842	Phage shock protein A
C7N18_RS25945	COG3766	membrane
C7N18_RS25950	COG5463	Belongs to the UPF0441 family
C7N18_RS25955	COG0754	glutathionylspermidine amidase activity
C7N18_RS25960	COG1960	acyl-CoA dehydrogenase activity
C7N18_RS25970	COG3650	response to hydrogen peroxide
C7N18_RS25975	COG1073	alpha beta
C7N18_RS25990	COG3037	sugar-specific permease SgaT UlaA
C7N18_RS25995	COG3414	Phosphotransferase system galactitol-specific IIB component
C7N18_RS26000	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7N18_RS26035	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C7N18_RS26060	COG0675	Transposase, IS605 OrfB family
C7N18_RS26070	COG3061	Opacity-associated protein A
C7N18_RS26080	COG0545	Peptidyl-prolyl cis-trans isomerase
C7N18_RS26085	COG1113	amino acid transport
C7N18_RS26095	COG0697	spore germination
C7N18_RS26100	COG0702	epimerase
C7N18_RS26105	COG1733	regulation of RNA biosynthetic process
C7N18_RS26110	COG0737	Belongs to the 5'-nucleotidase family
C7N18_RS26115	COG1218	3'(2'),5'-bisphosphate nucleotidase
C7N18_RS26125	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
C7N18_RS26135	COG1253	flavin adenine dinucleotide binding
C7N18_RS26145	COG0729	surface antigen
C7N18_RS26150	COG2911	Protein conserved in bacteria
C7N18_RS26155	COG2105	PFAM AIG2 family protein
C7N18_RS26160	COG2336	PFAM SpoVT AbrB
C7N18_RS26165	COG2337	Toxic component of a toxin-antitoxin (TA) module
C7N18_RS26170	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
C7N18_RS26175	COG1879	ABC-type sugar transport system periplasmic component
C7N18_RS26180	COG1129	ABC transporter
C7N18_RS26185	COG1172	Belongs to the binding-protein-dependent transport system permease family
C7N18_RS26190	COG1172	Belongs to the binding-protein-dependent transport system permease family
C7N18_RS26200	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C7N18_RS26210	COG0312	modulator of DNA gyrase
C7N18_RS26215	COG3783	Cytochrome b(562)
C7N18_RS26225	COG3077	Addiction module antitoxin, RelB DinJ family
C7N18_RS26230	COG0602	queuosine metabolic process
C7N18_RS26235	COG1328	CTP reductase activity
C7N18_RS26240	COG0366	Alpha amylase catalytic
C7N18_RS26245	COG1263	PTS System
C7N18_RS26245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7N18_RS26250	COG1609	Transcriptional regulator
C7N18_RS26260	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C7N18_RS26265	COG0251	oxidation-reduction process
C7N18_RS26285	COG0251	oxidation-reduction process
C7N18_RS26290	COG1028	Short-chain dehydrogenase reductase Sdr
C7N18_RS26295	COG1309	transcriptional regulator
C7N18_RS26300	COG2731	YhcH YjgK YiaL family protein
C7N18_RS26315	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
C7N18_RS26320	COG0456	acetyltransferase
C7N18_RS26325	COG4269	membrane
C7N18_RS26335	COG2927	DNA polymerase III (CHI subunit)
C7N18_RS26345	COG0795	lipopolysaccharide-transporting ATPase activity
C7N18_RS26350	COG0795	lipopolysaccharide-transporting ATPase activity
C7N18_RS26355	COG0433	COG0433 Predicted ATPase
C7N18_RS26360	COG1064	alcohol dehydrogenase
C7N18_RS26390	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
C7N18_RS26420	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C7N18_RS26435	COG0210	DNA helicase
C7N18_RS26450	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
C7N18_RS26455	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
C7N18_RS26460	COG0582	viral genome integration into host DNA
C7N18_RS26465	COG4974	Belongs to the 'phage' integrase family
C7N18_RS26470	COG3539	Fimbrial protein
C7N18_RS26475	COG3539	Fimbrial protein
C7N18_RS26480	COG3121	Chaperone
C7N18_RS26490	COG3539	Fimbrial protein
C7N18_RS26495	COG3539	Fimbrial protein
C7N18_RS26500	COG3539	Fimbrial protein
C7N18_RS26505	COG2610	gluconate transmembrane transporter activity
C7N18_RS26515	COG0246	Mannitol dehydrogenase
C7N18_RS26520	COG2186	Transcriptional regulator
C7N18_RS26540	COG0583	DNA-binding transcription factor activity
C7N18_RS26545	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C7N18_RS26550	COG0700	Nucleoside recognition
C7N18_RS26555	COG3366	ferrous iron transmembrane transporter activity
C7N18_RS26565	COG1388	LysM domain
C7N18_RS26565	COG1470	cell adhesion involved in biofilm formation
C7N18_RS26570	COG0477	Major facilitator Superfamily
C7N18_RS26575	COG3204	pilus organization
C7N18_RS26595	COG1924	4 iron, 4 sulfur cluster binding
C7N18_RS26600	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
C7N18_RS26610	COG2814	Major facilitator Superfamily
C7N18_RS26625	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7N18_RS26630	COG5457	Domain of unknown function (DUF1127)
C7N18_RS26640	COG0523	cobalamin synthesis protein
C7N18_RS26645	COG2879	small protein
C7N18_RS26650	COG1966	Carbon starvation protein
C7N18_RS26655	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C7N18_RS26660	COG2368	4-hydroxyphenylacetate
C7N18_RS26680	COG3971	2-oxopent-4-enoate hydratase activity
C7N18_RS26690	COG3384	dioxygenase
C7N18_RS26695	COG1012	belongs to the aldehyde dehydrogenase family
C7N18_RS26700	COG0179	Fumarylacetoacetate (FAA) hydrolase
C7N18_RS26705	COG1846	Transcriptional regulator
C7N18_RS26710	COG0840	transmembrane signaling receptor activity
C7N18_RS26725	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C7N18_RS26735	COG1802	Transcriptional regulator
C7N18_RS26740	COG1063	alcohol dehydrogenase
C7N18_RS26755	COG1484	DNA-dependent DNA replication
C7N18_RS26770	COG2966	Psort location CytoplasmicMembrane, score
C7N18_RS26775	COG2197	response regulator
C7N18_RS26780	COG2197	response regulator
C7N18_RS26785	COG4114	ferric iron reductase
C7N18_RS26815	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
C7N18_RS26820	COG0456	acetyltransferase
C7N18_RS26825	COG1011	Hydrolase
C7N18_RS26830	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
C7N18_RS26890	COG0740	serine-type endopeptidase activity
C7N18_RS26965	COG5301	cellulose 1,4-beta-cellobiosidase activity
C7N18_RS26970	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C7N18_RS26975	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C7N18_RS27005	COG2823	Periplasmic or secreted lipoprotein
C7N18_RS27015	COG4667	esterase of the alpha-beta hydrolase superfamily
C7N18_RS27020	COG0084	hydrolase, TatD family'
C7N18_RS27025	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C7N18_RS27065	COG3726	membrane protein affecting hemolysin expression
C7N18_RS27070	COG0560	Phosphoserine phosphatase
C7N18_RS27075	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C7N18_RS27080	COG1056	cytidyltransferase-related domain
C7N18_RS27080	COG3172	ATPase kinase involved in NAD metabolism
C7N18_RS27085	COG1902	pentaerythritol trinitrate reductase activity
C7N18_RS27110	COG0583	DNA-binding transcription factor activity
C7N18_RS27115	COG0488	(ABC) transporter
C7N18_RS27140	COG2207	Transcriptional regulator
C7N18_RS27140	COG3708	Transcriptional regulator
C7N18_RS27145	COG3045	CreA protein
C7N18_RS27150	COG0745	RESPONSE REGULATOR receiver
C7N18_RS27155	COG2205	protein histidine kinase activity
C7N18_RS27160	COG4452	Inner membrane protein CreD
C7N18_RS27165	COG0745	RESPONSE REGULATOR receiver
C7N18_RS27175	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
C7N18_RS27185	COG0460	homoserine dehydrogenase
C7N18_RS27185	COG0527	aspartate kinase activity
C7N18_RS27195	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C7N18_RS27210	COG1115	amino acid carrier protein
C7N18_RS27215	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C7N18_RS27220	COG0521	Mo-molybdopterin cofactor biosynthetic process
C7N18_RS27225	COG1584	GPR1 FUN34 yaaH family protein
C7N18_RS27230	COG4735	regulation of single-species biofilm formation
C7N18_RS27260	COG0583	DNA-binding transcription factor activity
C7N18_RS27275	COG3121	Chaperone
C7N18_RS27300	COG0196	riboflavin kinase activity
C7N18_RS27315	COG1047	Peptidyl-prolyl cis-trans
C7N18_RS27335	COG0505	Belongs to the CarA family
C7N18_RS27340	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C7N18_RS27390	COG0644	oxidoreductase
C7N18_RS27395	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C7N18_RS27400	COG2271	Major facilitator Superfamily
C7N18_RS27415	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C7N18_RS27450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C7N18_RS27460	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
C7N18_RS27465	COG1357	PFAM Pentapeptide repeats (8 copies)
C7N18_RS27475	COG0564	pseudouridine synthase activity
C7N18_RS27485	COG0417	DNA replication proofreading
C7N18_RS27490	COG0235	Class ii aldolase
C7N18_RS27500	COG1069	ribulokinase activity
C7N18_RS27505	COG4977	sequence-specific DNA binding
C7N18_RS27510	COG0586	Pfam SNARE associated Golgi protein
C7N18_RS27520	COG1178	ABC-type Fe3 transport system permease component
C7N18_RS27525	COG4143	(ABC) transporter
C7N18_RS27570	COG0583	DNA-binding transcription factor activity
C7N18_RS27575	COG0028	Belongs to the TPP enzyme family
C7N18_RS27580	COG0440	acetolactate synthase activity
C7N18_RS27590	COG1609	Transcriptional regulator
C7N18_RS27605	COG3116	cell division
C7N18_RS27615	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C7N18_RS27620	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C7N18_RS27630	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C7N18_RS27635	COG0772	Belongs to the SEDS family
C7N18_RS27650	COG1181	Belongs to the D-alanine--D-alanine ligase family
C7N18_RS27655	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C7N18_RS27660	COG0849	cell division
C7N18_RS27665	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C7N18_RS27685	COG0494	nUDIX hydrolase
C7N18_RS27710	COG1459	type II secretion system
C7N18_RS27715	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C7N18_RS27720	COG4969	Belongs to the N-Me-Phe pilin family
C7N18_RS27725	COG0157	Belongs to the NadC ModD family
C7N18_RS27730	COG3023	N-Acetylmuramoyl-L-alanine amidase
C7N18_RS27735	COG3725	Membrane protein required for beta-lactamase induction
C7N18_RS27845	COG3436	PFAM IS66 Orf2 family protein
C7N18_RS27850	COG4372	Transposase
C7N18_RS27965	COG4372	Transposase
C7N18_RS27970	COG3436	PFAM IS66 Orf2 family protein