locus-tag	class	description
H5C70_RS00010	COG0592	DNA-directed DNA polymerase activity
H5C70_RS00020	COG0187	DNA topoisomerase II activity
H5C70_RS00025	COG3753	Protein conserved in bacteria
H5C70_RS00030	COG0561	phosphatase activity
H5C70_RS00040	COG2186	Transcriptional regulator
H5C70_RS00045	COG3734	2-keto-3-deoxy-galactonokinase
H5C70_RS00050	COG0800	Aldolase
H5C70_RS00060	COG2271	Major facilitator Superfamily
H5C70_RS00070	COG0823	Involved in the tonB-independent uptake of proteins
H5C70_RS00075	COG5645	(Lipo)protein
H5C70_RS00095	COG2188	Transcriptional regulator
H5C70_RS00115	COG2207	Transcriptional regulator
H5C70_RS00120	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H5C70_RS00125	COG3119	arylsulfatase activity
H5C70_RS00135	COG2149	membrane
H5C70_RS00145	COG0641	radical SAM
H5C70_RS00150	COG2814	Major facilitator Superfamily
H5C70_RS00165	COG0028	Belongs to the TPP enzyme family
H5C70_RS00170	COG0440	acetolactate synthase activity
H5C70_RS00175	COG2197	response regulator
H5C70_RS00180	COG3851	Histidine kinase
H5C70_RS00185	COG2271	Major facilitator Superfamily
H5C70_RS00190	COG2271	Major facilitator Superfamily
H5C70_RS00200	COG2252	PERMEase
H5C70_RS00220	COG1464	Belongs to the NlpA lipoprotein family
H5C70_RS00225	COG0697	spore germination
H5C70_RS00230	COG2814	Major facilitator Superfamily
H5C70_RS00240	COG2211	Major facilitator Superfamily
H5C70_RS00245	COG1501	Belongs to the glycosyl hydrolase 31 family
H5C70_RS00250	COG2982	Protein involved in outer membrane biogenesis
H5C70_RS00255	COG2233	PERMEase
H5C70_RS00260	COG0786	glutamate:sodium symporter activity
H5C70_RS00270	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H5C70_RS00275	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H5C70_RS00280	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H5C70_RS00290	COG0194	GDP metabolic process
H5C70_RS00300	COG2860	membrane
H5C70_RS00305	COG3645	SOS response
H5C70_RS00310	COG3645	SOS response
H5C70_RS00400	COG1561	YicC-like family, N-terminal region
H5C70_RS00425	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H5C70_RS00455	COG1519	Transferase
H5C70_RS00460	COG0859	PFAM glycosyl transferase family 9
H5C70_RS00465	COG0438	transferase activity, transferring glycosyl groups
H5C70_RS00470	COG0515	serine threonine protein kinase
H5C70_RS00485	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H5C70_RS00490	COG1442	glycosyl transferase family 8
H5C70_RS00495	COG1216	Glycosyl transferase, family 2
H5C70_RS00500	COG3307	-O-antigen
H5C70_RS00505	COG0859	PFAM glycosyl transferase family 9
H5C70_RS00510	COG0859	PFAM glycosyl transferase family 9
H5C70_RS00520	COG0156	8-amino-7-oxononanoate synthase activity
H5C70_RS00530	COG1216	Glycosyl transferase, family 2
H5C70_RS00535	COG2861	carbohydrate metabolic process
H5C70_RS00540	COG4942	peptidase
H5C70_RS00550	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H5C70_RS00555	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H5C70_RS00570	COG1045	serine acetyltransferase
H5C70_RS00575	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H5C70_RS00585	COG2186	Transcriptional regulator
H5C70_RS00590	COG1620	l-lactate permease
H5C70_RS00595	COG5295	Hep Hag repeat protein
H5C70_RS00615	COG3722	fumarate hydratase activity
H5C70_RS00625	COG2213	PTS system mannitol-specific
H5C70_RS00625	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H5C70_RS00635	COG1566	PFAM secretion protein HlyD family protein
H5C70_RS00645	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
H5C70_RS00655	COG1413	lyase activity
H5C70_RS00665	COG3209	COG3209 Rhs family protein
H5C70_RS00670	COG0625	glutathione transferase activity
H5C70_RS00680	COG3276	selenocysteine insertion sequence binding
H5C70_RS00685	COG1454	alcohol dehydrogenase
H5C70_RS00690	COG1012	belongs to the aldehyde dehydrogenase family
H5C70_RS00705	COG1566	PFAM secretion protein HlyD family protein
H5C70_RS00710	COG0583	DNA-binding transcription factor activity
H5C70_RS00715	COG3713	MltA-interacting MipA family protein
H5C70_RS00725	COG2211	Major facilitator Superfamily
H5C70_RS00735	COG0235	Class ii aldolase
H5C70_RS00740	COG3623	hexulose-6-phosphate isomerase
H5C70_RS00745	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
H5C70_RS00750	COG1070	Carbohydrate kinase
H5C70_RS00755	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H5C70_RS00760	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
H5C70_RS00765	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
H5C70_RS00770	COG2731	YhcH YjgK YiaL family protein
H5C70_RS00780	COG1414	Transcriptional regulator
H5C70_RS00785	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H5C70_RS00790	COG3977	Valine--pyruvate aminotransferase
H5C70_RS00795	COG0366	Alpha amylase catalytic
H5C70_RS00800	COG2992	FlgJ-related protein
H5C70_RS00805	COG2207	Transcriptional regulator
H5C70_RS00805	COG1609	Transcriptional regulator
H5C70_RS00810	COG4214	carbohydrate transport
H5C70_RS00815	COG1129	ABC transporter
H5C70_RS00820	COG4213	ABC transporter substrate-binding protein
H5C70_RS00830	COG1070	Carbohydrate kinase
H5C70_RS00835	COG4682	membrane
H5C70_RS00840	COG4682	membrane
H5C70_RS00845	COG3274	enterobacterial common antigen metabolic process
H5C70_RS00870	COG1278	Cold shock
H5C70_RS00875	COG2944	sequence-specific DNA binding
H5C70_RS00890	COG2885	chlorophyll binding
H5C70_RS00895	COG0243	molybdopterin cofactor binding
H5C70_RS00900	COG0456	acetyltransferase
H5C70_RS00905	COG2818	Glycosylase
H5C70_RS00910	COG5571	outer membrane autotransporter
H5C70_RS00915	COG2223	nitrite transmembrane transporter activity
H5C70_RS00920	COG2194	sulfuric ester hydrolase activity
H5C70_RS00935	COG0747	negative chemotaxis
H5C70_RS00940	COG0601	transmembrane transport
H5C70_RS00945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H5C70_RS00950	COG0444	Belongs to the ABC transporter superfamily
H5C70_RS00955	COG4608	Belongs to the ABC transporter superfamily
H5C70_RS00960	COG0814	amino acid
H5C70_RS00995	COG1215	transferase activity, transferring glycosyl groups
H5C70_RS01000	COG1215	transferase activity, transferring glycosyl groups
H5C70_RS01005	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
H5C70_RS01010	COG0457	Tetratricopeptide repeat
H5C70_RS01010	COG3118	belongs to the thioredoxin family
H5C70_RS01015	COG2199	diguanylate cyclase activity
H5C70_RS01015	COG2200	EAL domain
H5C70_RS01025	COG0612	Peptidase, M16
H5C70_RS01035	COG2200	EAL domain
H5C70_RS01040	COG2982	Protein involved in outer membrane biogenesis
H5C70_RS01045	COG0477	Major facilitator Superfamily
H5C70_RS01050	COG1295	ribonuclease BN
H5C70_RS01055	COG0583	DNA-binding transcription factor activity
H5C70_RS01060	COG2197	response regulator
H5C70_RS01070	COG1858	cytochrome C peroxidase
H5C70_RS01075	COG0076	glutamate decarboxylase activity
H5C70_RS01085	COG2207	Transcriptional regulator
H5C70_RS01090	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H5C70_RS01095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H5C70_RS01105	COG2771	luxR family
H5C70_RS01110	COG3247	response to pH
H5C70_RS01125	COG1285	pathogenesis
H5C70_RS01130	COG2197	response regulator
H5C70_RS01135	COG3065	identical protein binding
H5C70_RS01155	COG1393	Belongs to the ArsC family
H5C70_RS01160	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
H5C70_RS01165	COG0640	Transcriptional regulator
H5C70_RS01175	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H5C70_RS01180	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
H5C70_RS01185	COG0339	signal peptide processing
H5C70_RS01195	COG3104	oligopeptide transport
H5C70_RS01200	COG0589	response to stress
H5C70_RS01210	COG0306	phosphate transporter
H5C70_RS01215	COG2081	HI0933 family
H5C70_RS01235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H5C70_RS01240	COG0842	Transport permease protein
H5C70_RS01240	COG1129	ABC transporter
H5C70_RS01245	COG0842	Transport permease protein
H5C70_RS01270	COG0444	Belongs to the ABC transporter superfamily
H5C70_RS01275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H5C70_RS01280	COG0601	transmembrane transport
H5C70_RS01285	COG0747	negative chemotaxis
H5C70_RS01290	COG2091	lysine biosynthetic process via aminoadipic acid
H5C70_RS01295	COG0628	permease
H5C70_RS01310	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
H5C70_RS01325	COG3714	YhhN family
H5C70_RS01335	COG3776	membrane
H5C70_RS01340	COG0742	ribosomal rna small subunit methyltransferase
H5C70_RS01345	COG0552	protein localization to endoplasmic reticulum
H5C70_RS01350	COG2884	Cell division ATP-binding protein ftsE
H5C70_RS01355	COG2177	Part of the ABC transporter FtsEX involved in
H5C70_RS01360	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H5C70_RS01365	COG0683	leucine binding
H5C70_RS01380	COG0456	acetyltransferase
H5C70_RS01385	COG0683	leucine binding
H5C70_RS01390	COG0559	Belongs to the binding-protein-dependent transport system permease family
H5C70_RS01395	COG4177	L-phenylalanine transmembrane transporter activity
H5C70_RS01400	COG0411	ABC transporter
H5C70_RS01405	COG0410	ABC transporter
H5C70_RS01410	COG1653	transport
H5C70_RS01415	COG1175	transmembrane transport
H5C70_RS01425	COG3842	ATPase activity
H5C70_RS01430	COG0584	glycerophosphoryl diester phosphodiesterase
H5C70_RS01440	COG0405	Gamma-glutamyltransferase
H5C70_RS01460	COG3157	Type VI secretion system effector, Hcp
H5C70_RS01465	COG1247	-acetyltransferase
H5C70_RS01470	COG0673	inositol 2-dehydrogenase activity
H5C70_RS01475	COG1741	Belongs to the pirin family
H5C70_RS01480	COG1609	Transcriptional regulator
H5C70_RS01485	COG3265	gluconokinase activity
H5C70_RS01490	COG2610	gluconate transmembrane transporter activity
H5C70_RS01495	COG2095	MarC family integral membrane protein
H5C70_RS01500	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H5C70_RS01525	COG0058	SHG alpha-glucan phosphorylase activity
H5C70_RS01530	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H5C70_RS01550	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
H5C70_RS01565	COG1349	DNA-binding transcription factor activity
H5C70_RS01570	COG4650	regulator
H5C70_RS01575	COG1690	Belongs to the RtcB family
H5C70_RS01590	COG0058	SHG alpha-glucan phosphorylase activity
H5C70_RS01595	COG1640	4-alpha-glucanotransferase
H5C70_RS01600	COG2610	gluconate transmembrane transporter activity
H5C70_RS01620	COG5464	transposase or invertase
H5C70_RS01630	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
H5C70_RS01635	COG1918	ferrous iron import across plasma membrane
H5C70_RS01640	COG2183	response to ionizing radiation
H5C70_RS01645	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H5C70_RS01675	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
H5C70_RS01685	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H5C70_RS01690	COG1011	Hydrolase
H5C70_RS01700	COG0494	nUDIX hydrolase
H5C70_RS01705	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
H5C70_RS01710	COG4972	Pilus assembly protein
H5C70_RS01715	COG3166	PFAM Fimbrial assembly family protein
H5C70_RS01730	COG4796	Type ii and iii secretion system protein
H5C70_RS01745	COG3266	domain, Protein
H5C70_RS01750	COG0338	D12 class N6 adenine-specific DNA methyltransferase
H5C70_RS01755	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H5C70_RS01760	COG0546	phosphoglycolate phosphatase activity
H5C70_RS01765	COG0180	Tryptophanyl-tRNA synthetase
H5C70_RS01770	COG2188	Transcriptional regulator
H5C70_RS01780	COG3457	Alanine racemase
H5C70_RS01785	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
H5C70_RS01790	COG1735	metal-dependent hydrolase with the TIM-barrel fold
H5C70_RS01805	COG0626	cystathionine gamma-synthase activity
H5C70_RS01810	COG2188	Transcriptional regulator
H5C70_RS01820	COG1082	Xylose isomerase domain protein TIM barrel
H5C70_RS01825	COG2222	sugar isomerase
H5C70_RS01830	COG0531	amino acid
H5C70_RS01845	COG2116	formate transmembrane transporter activity
H5C70_RS01850	COG2146	nitrite reductase [NAD(P)H] activity
H5C70_RS01855	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H5C70_RS01865	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H5C70_RS01875	COG2184	nucleotidyltransferase activity
H5C70_RS01880	COG0512	Glutamine amidotransferase of anthranilate synthase
H5C70_RS01885	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H5C70_RS01890	COG1289	transmembrane transporter activity
H5C70_RS01895	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H5C70_RS01900	COG1765	OsmC-like protein
H5C70_RS01905	COG3954	Phosphoribulokinase
H5C70_RS01915	COG0429	hydrolase of the alpha beta-hydrolase fold
H5C70_RS01920	COG0488	(ABC) transporter
H5C70_RS01935	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
H5C70_RS01940	COG1047	Peptidyl-prolyl cis-trans
H5C70_RS01950	COG0545	Peptidyl-prolyl cis-trans isomerase
H5C70_RS01955	COG2964	Protein conserved in bacteria
H5C70_RS02025	COG0089	rRNA binding
H5C70_RS02115	COG0201	protein transport
H5C70_RS02155	COG0789	Transcriptional regulator
H5C70_RS02160	COG4372	Transposase
H5C70_RS02165	COG3436	PFAM IS66 Orf2 family protein
H5C70_RS02175	COG3036	rescue of stalled ribosome
H5C70_RS02185	COG0569	domain protein
H5C70_RS02205	COG0758	DNA mediated transformation
H5C70_RS02215	COG0551	DNA topoisomerase type I activity
H5C70_RS02235	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H5C70_RS02275	COG1126	abc transporter atp-binding protein
H5C70_RS02280	COG0765	amino acid transport
H5C70_RS02285	COG4597	amino acid ABC transporter
H5C70_RS02290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H5C70_RS02300	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H5C70_RS02305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H5C70_RS02310	COG1309	transcriptional regulator
H5C70_RS02320	COG2189	Belongs to the N(4) N(6)-methyltransferase family
H5C70_RS02330	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H5C70_RS02340	COG4145	pantothenate transmembrane transporter activity
H5C70_RS02345	COG3924	membrane
H5C70_RS02350	COG0439	Biotin carboxylase
H5C70_RS02355	COG0511	ligase activity, forming carbon-carbon bonds
H5C70_RS02360	COG0604	alcohol dehydrogenase
H5C70_RS02365	COG2200	EAL domain
H5C70_RS02365	COG2199	diguanylate cyclase activity
H5C70_RS02370	COG1077	Cell shape determining protein MreB Mrl
H5C70_RS02375	COG1792	Involved in formation and maintenance of cell shape
H5C70_RS02380	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
H5C70_RS02390	COG1530	ribonuclease E activity
H5C70_RS02395	COG3164	Protein of unknown function
H5C70_RS02400	COG0312	modulator of DNA gyrase
H5C70_RS02405	COG0583	DNA-binding transcription factor activity
H5C70_RS02425	COG2732	(Barnase) inhibitor
H5C70_RS02445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H5C70_RS02450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H5C70_RS02455	COG3105	Protein conserved in bacteria
H5C70_RS02460	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
H5C70_RS02475	COG0625	glutathione transferase activity
H5C70_RS02480	COG2969	positive regulation of protein catabolic process
H5C70_RS02485	COG3069	C4-dicarboxylate transmembrane transporter activity
H5C70_RS02515	COG2731	YhcH YjgK YiaL family protein
H5C70_RS02520	COG4804	nuclease activity
H5C70_RS02525	COG0493	'glutamate synthase
H5C70_RS02530	COG0067	glutamate synthase
H5C70_RS02530	COG0069	glutamate synthase activity
H5C70_RS02530	COG0070	glutamate synthase
H5C70_RS02535	COG1242	4 iron, 4 sulfur cluster binding
H5C70_RS02540	COG5002	protein histidine kinase activity
H5C70_RS02540	COG0784	Response regulator, receiver
H5C70_RS02540	COG2198	Histidine kinase
H5C70_RS02545	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
H5C70_RS02555	COG0515	serine threonine protein kinase
H5C70_RS02560	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H5C70_RS02575	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
H5C70_RS02580	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
H5C70_RS02585	COG1137	ATPase activity
H5C70_RS02590	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
H5C70_RS02595	COG3117	lipopolysaccharide transmembrane transporter activity
H5C70_RS02600	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
H5C70_RS02605	COG0517	IMP dehydrogenase activity
H5C70_RS02605	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H5C70_RS02610	COG0530	calcium, potassium:sodium antiporter activity
H5C70_RS02615	COG1127	ABC transporter
H5C70_RS02620	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H5C70_RS02625	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H5C70_RS02630	COG2854	intermembrane phospholipid transfer
H5C70_RS02635	COG3113	response to antibiotic
H5C70_RS02640	COG5007	Belongs to the BolA IbaG family
H5C70_RS02650	COG3423	Transcriptional regulator
H5C70_RS02655	COG0142	geranyltranstransferase activity
H5C70_RS02670	COG0697	spore germination
H5C70_RS02680	COG2027	D-alanyl-D-alanine carboxypeptidase
H5C70_RS02685	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H5C70_RS02690	COG1534	Rna-binding protein
H5C70_RS02700	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H5C70_RS02705	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H5C70_RS02715	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H5C70_RS02725	COG2194	sulfuric ester hydrolase activity
H5C70_RS02745	COG0195	Participates in both transcription termination and antitermination
H5C70_RS02785	COG0513	Belongs to the DEAD box helicase family
H5C70_RS02790	COG0814	amino acid
H5C70_RS02795	COG3547	Transposase (IS116 IS110 IS902 family)
H5C70_RS02800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H5C70_RS02805	COG0826	peptidase U32
H5C70_RS02810	COG0826	peptidase U32
H5C70_RS02815	COG3154	lipid carrier protein
H5C70_RS02820	COG3153	acetyltransferase
H5C70_RS02835	COG0693	protein deglycase activity
H5C70_RS02840	COG0702	epimerase
H5C70_RS02845	COG0701	Predicted permease
H5C70_RS02850	COG2823	Periplasmic or secreted lipoprotein
H5C70_RS02870	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
H5C70_RS02875	COG3539	Fimbrial protein
H5C70_RS02880	COG3188	usher protein
H5C70_RS02885	COG3121	Chaperone
H5C70_RS02890	COG3539	Fimbrial protein
H5C70_RS02895	COG0363	glucosamine-6-phosphate deaminase activity
H5C70_RS02900	COG3716	PTS system mannose fructose sorbose family IID component
H5C70_RS02905	COG3715	PTS system
H5C70_RS02910	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H5C70_RS02920	COG2222	sugar isomerase
H5C70_RS02925	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
H5C70_RS02930	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
H5C70_RS02935	COG3716	PTS system mannose fructose sorbose family IID component
H5C70_RS02945	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H5C70_RS02955	COG1349	DNA-binding transcription factor activity
H5C70_RS02965	COG2002	toxin-antitoxin pair type II binding
H5C70_RS02970	COG2721	sulfolactate sulfo-lyase activity
H5C70_RS02975	COG2271	Major facilitator Superfamily
H5C70_RS02985	COG2084	Dehydrogenase
H5C70_RS02990	COG1929	Belongs to the glycerate kinase type-1 family
H5C70_RS03015	COG0583	DNA-binding transcription factor activity
H5C70_RS03020	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H5C70_RS03030	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H5C70_RS03035	COG1882	Formate acetyltransferase
H5C70_RS03045	COG1760	l-serine dehydratase
H5C70_RS03050	COG0814	amino acid
H5C70_RS03065	COG1741	Belongs to the pirin family
H5C70_RS03070	COG0583	DNA-binding transcription factor activity
H5C70_RS03075	COG3152	Membrane
H5C70_RS03080	COG3152	Membrane
H5C70_RS03085	COG0435	Glutathione S-transferase
H5C70_RS03090	COG2259	Doxx family
H5C70_RS03100	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
H5C70_RS03105	COG4575	ribosome binding
H5C70_RS03110	COG1422	Protein of unknown function (DUF1090)
H5C70_RS03120	COG0586	Pfam SNARE associated Golgi protein
H5C70_RS03125	COG2186	Transcriptional regulator
H5C70_RS03150	COG2271	Major facilitator Superfamily
H5C70_RS03160	COG2721	sulfolactate sulfo-lyase activity
H5C70_RS03170	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
H5C70_RS03175	COG0861	Integral membrane protein TerC family
H5C70_RS03180	COG0673	inositol 2-dehydrogenase activity
H5C70_RS03185	COG2949	membrane
H5C70_RS03190	COG1451	nucleotide metabolic process
H5C70_RS03205	COG5499	transcription regulator containing HTH domain
H5C70_RS03210	COG1902	pentaerythritol trinitrate reductase activity
H5C70_RS03210	COG0446	pyridine nucleotide-disulphide oxidoreductase
H5C70_RS03215	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
H5C70_RS03215	COG3408	Glycogen debranching enzyme
H5C70_RS03225	COG0531	amino acid
H5C70_RS03230	COG2731	YhcH YjgK YiaL family protein
H5C70_RS03235	COG3250	beta-galactosidase activity
H5C70_RS03240	COG1609	Transcriptional regulator
H5C70_RS03245	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H5C70_RS03255	COG0840	transmembrane signaling receptor activity
H5C70_RS03260	COG1695	Transcriptional regulator
H5C70_RS03265	COG2375	cellular response to nickel ion
H5C70_RS03280	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H5C70_RS03285	COG0358	DNA primase activity
H5C70_RS03290	COG0828	Belongs to the bacterial ribosomal protein bS21 family
H5C70_RS03300	COG0471	metal ion transport
H5C70_RS03305	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H5C70_RS03310	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
H5C70_RS03315	COG0583	DNA-binding transcription factor activity
H5C70_RS03325	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
H5C70_RS03340	COG4991	sh3 domain protein
H5C70_RS03345	COG3025	triphosphatase activity
H5C70_RS03370	COG2268	Band 7 protein
H5C70_RS03375	COG1585	Membrane protein implicated in regulation of membrane protease activity
H5C70_RS03385	COG3539	Fimbrial protein
H5C70_RS03390	COG3121	Chaperone
H5C70_RS03395	COG3188	usher protein
H5C70_RS03400	COG3539	Fimbrial protein
H5C70_RS03405	COG2960	long-chain fatty acid transporting porin activity
H5C70_RS03425	COG3384	dioxygenase
H5C70_RS03430	COG0754	glutathionylspermidine amidase activity
H5C70_RS03440	COG1538	Outer membrane efflux protein
H5C70_RS03445	COG0494	nUDIX hydrolase
H5C70_RS03450	COG3151	Protein conserved in bacteria
H5C70_RS03455	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H5C70_RS03460	COG3150	esterase
H5C70_RS03465	COG0187	DNA topoisomerase II activity
H5C70_RS03515	COG2211	Major facilitator Superfamily
H5C70_RS03520	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H5C70_RS03525	COG2249	NAD(P)H dehydrogenase (quinone) activity
H5C70_RS03535	COG0642	Histidine kinase
H5C70_RS03540	COG0745	RESPONSE REGULATOR receiver
H5C70_RS03545	COG3111	PFAM Bacterial OB fold (BOF) protein
H5C70_RS03550	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
H5C70_RS03555	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H5C70_RS03560	COG0204	Acyl-transferase
H5C70_RS03565	COG2132	Multicopper oxidase
H5C70_RS03570	COG1032	radical SAM domain protein
H5C70_RS03575	COG4238	major outer membrane lipoprotein
H5C70_RS03585	COG0656	L-ascorbic acid biosynthetic process
H5C70_RS03590	COG1979	alcohol dehydrogenase
H5C70_RS03595	COG2207	Transcriptional regulator
H5C70_RS03600	COG0586	Pfam SNARE associated Golgi protein
H5C70_RS03605	COG0626	cystathionine gamma-synthase activity
H5C70_RS03610	COG0811	peptide transport
H5C70_RS03615	COG0848	biopolymer transport protein
H5C70_RS03620	COG1028	Short-chain dehydrogenase reductase Sdr
H5C70_RS03630	COG0667	Aldo Keto reductase
H5C70_RS03645	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
H5C70_RS03650	COG0437	4 iron, 4 sulfur cluster binding
H5C70_RS03655	COG5557	Pfam Polysulphide reductase, NrfD
H5C70_RS03660	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
H5C70_RS03665	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
H5C70_RS03670	COG1773	rubredoxin
H5C70_RS03675	COG0375	protein maturation
H5C70_RS03680	COG0298	carbon dioxide binding
H5C70_RS03685	COG3547	Transposase (IS116 IS110 IS902 family)
H5C70_RS03690	COG0625	glutathione transferase activity
H5C70_RS03695	COG0754	glutathionylspermidine amidase activity
H5C70_RS03700	COG0306	phosphate transporter
H5C70_RS03705	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
H5C70_RS03710	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
H5C70_RS03715	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
H5C70_RS03720	COG2244	polysaccharide biosynthetic process
H5C70_RS03730	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
H5C70_RS03735	COG0795	lipopolysaccharide-transporting ATPase activity
H5C70_RS03745	COG0156	8-amino-7-oxononanoate synthase activity
H5C70_RS03750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H5C70_RS03775	COG0456	acetyltransferase
H5C70_RS03780	COG2186	Transcriptional regulator
H5C70_RS03785	COG0277	FAD linked oxidase domain protein
H5C70_RS03790	COG0277	FAD linked oxidase domain protein
H5C70_RS03795	COG0247	lactate metabolic process
H5C70_RS03800	COG3193	protein, possibly involved in utilization of glycolate and propanediol
H5C70_RS03805	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H5C70_RS03810	COG1620	l-lactate permease
H5C70_RS03815	COG3064	Membrane
H5C70_RS03840	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H5C70_RS03845	COG1459	type II secretion system
H5C70_RS03850	COG2165	general secretion pathway protein
H5C70_RS03880	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
H5C70_RS03890	COG1811	Na channel or pump
H5C70_RS03895	COG1982	Orn Lys Arg decarboxylase major
H5C70_RS03900	COG2211	Major facilitator Superfamily
H5C70_RS03915	COG1194	a g-specific adenine glycosylase
H5C70_RS03925	COG3171	Protein conserved in bacteria
H5C70_RS03935	COG0252	asparaginase activity
H5C70_RS03945	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H5C70_RS03960	COG0762	integral membrane protein
H5C70_RS03965	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
H5C70_RS03970	COG2805	Type II/IV secretion system protein
H5C70_RS03975	COG3547	Transposase (IS116 IS110 IS902 family)
H5C70_RS03990	COG0189	ligase activity
H5C70_RS03995	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H5C70_RS04000	COG2356	endonuclease I
H5C70_RS04010	COG2814	Major facilitator Superfamily
H5C70_RS04030	COG1166	arginine decarboxylase activity
H5C70_RS04045	COG0501	Belongs to the peptidase M48B family
H5C70_RS04050	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H5C70_RS04055	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H5C70_RS04060	COG2213	PTS system mannitol-specific
H5C70_RS04065	COG1063	alcohol dehydrogenase
H5C70_RS04070	COG1494	fructose-1,6-bisphosphatase
H5C70_RS04085	COG1122	ATPase activity
H5C70_RS04090	COG1122	ATPase activity
H5C70_RS04120	COG0191	fructose-bisphosphate aldolase activity
H5C70_RS04125	COG0668	transmembrane transport
H5C70_RS04135	COG2968	Membrane
H5C70_RS04145	COG4372	Transposase
H5C70_RS04150	COG3436	PFAM IS66 Orf2 family protein
H5C70_RS04165	COG0427	acetyl-CoA hydrolase
H5C70_RS04170	COG1024	Enoyl-CoA hydratase
H5C70_RS04175	COG1703	isobutyryl-CoA mutase activity
H5C70_RS04180	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
H5C70_RS04180	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
H5C70_RS04200	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H5C70_RS04215	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H5C70_RS04235	COG0006	proline dipeptidase activity
H5C70_RS04240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H5C70_RS04245	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H5C70_RS04270	COG1028	Short-chain dehydrogenase reductase Sdr
H5C70_RS04275	COG2723	6-phospho-beta-galactosidase activity
H5C70_RS04285	COG1272	protein, Hemolysin III
H5C70_RS04295	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
H5C70_RS04305	COG0716	FMN binding
H5C70_RS04310	COG4974	Belongs to the 'phage' integrase family
H5C70_RS04315	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H5C70_RS04320	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H5C70_RS04350	COG2233	PERMEase
H5C70_RS04355	COG0493	'glutamate synthase
H5C70_RS04355	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H5C70_RS04360	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H5C70_RS04365	COG2252	PERMEase
H5C70_RS04370	COG0402	S-adenosylhomocysteine deaminase activity
H5C70_RS04375	COG2233	PERMEase
H5C70_RS04380	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H5C70_RS04380	COG2080	2 iron, 2 sulfur cluster binding
H5C70_RS04385	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
H5C70_RS04390	COG0402	S-adenosylhomocysteine deaminase activity
H5C70_RS04395	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H5C70_RS04395	COG0493	'glutamate synthase
H5C70_RS04400	COG2068	MobA-Related Protein
H5C70_RS04405	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H5C70_RS04410	COG3608	succinylglutamate desuccinylase aspartoacylase
H5C70_RS04410	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
H5C70_RS04415	COG0549	Belongs to the carbamate kinase family
H5C70_RS04425	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H5C70_RS04430	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H5C70_RS04435	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
H5C70_RS04440	COG3829	transcription factor binding
H5C70_RS04445	COG2080	2 iron, 2 sulfur cluster binding
H5C70_RS04450	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
H5C70_RS04455	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H5C70_RS04460	COG4942	peptidase
H5C70_RS04470	COG3387	PFAM Glycoside hydrolase 15-related
H5C70_RS04565	COG0457	Tetratricopeptide repeat
H5C70_RS04565	COG3710	Transcriptional regulator
H5C70_RS04570	COG0457	Tetratricopeptide repeat
H5C70_RS04595	COG3710	Transcriptional regulator
H5C70_RS04600	COG2771	luxR family
H5C70_RS04605	COG0814	amino acid
H5C70_RS04610	COG0183	Belongs to the thiolase family
H5C70_RS04620	COG1028	Short-chain dehydrogenase reductase Sdr
H5C70_RS04625	COG2814	Major facilitator Superfamily
H5C70_RS04630	COG1794	racemase activity, acting on amino acids and derivatives
H5C70_RS04635	COG0583	DNA-binding transcription factor activity
H5C70_RS04645	COG1609	Transcriptional regulator
H5C70_RS04660	COG0667	Aldo Keto reductase
H5C70_RS04670	COG0861	Integral membrane protein TerC family
H5C70_RS04685	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
H5C70_RS04700	COG2165	general secretion pathway protein
H5C70_RS04705	COG4795	General secretion pathway protein
H5C70_RS04715	COG4967	type IV pilus modification protein PilV
H5C70_RS04720	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
H5C70_RS04725	COG1025	Belongs to the peptidase M16 family
H5C70_RS04730	COG1074	ATP-dependent DNA helicase activity
H5C70_RS04735	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H5C70_RS04740	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
H5C70_RS04740	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
H5C70_RS04745	COG0860	N-Acetylmuramoyl-L-alanine amidase
H5C70_RS04765	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
H5C70_RS04770	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H5C70_RS04775	COG2166	iron-sulfur cluster assembly
H5C70_RS04780	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H5C70_RS04790	COG0583	DNA-binding transcription factor activity
H5C70_RS04795	COG2363	Small membrane protein
H5C70_RS04805	COG1349	DNA-binding transcription factor activity
H5C70_RS04815	COG1070	Carbohydrate kinase
H5C70_RS04825	COG0738	Major facilitator superfamily
H5C70_RS04830	COG0235	Class ii aldolase
H5C70_RS04835	COG1454	alcohol dehydrogenase
H5C70_RS04845	COG1760	l-serine dehydratase
H5C70_RS04850	COG0814	amino acid
H5C70_RS04855	COG1611	Belongs to the LOG family
H5C70_RS04870	COG3098	single-species biofilm formation
H5C70_RS04875	COG0564	pseudouridine synthase activity
H5C70_RS04880	COG0716	FMN binding
H5C70_RS04885	COG2271	Major facilitator Superfamily
H5C70_RS04890	COG4948	Mandelate Racemase Muconate Lactonizing
H5C70_RS04895	COG4948	Mandelate Racemase Muconate Lactonizing
H5C70_RS04900	COG4999	Histidine kinase
H5C70_RS04900	COG3437	response regulator, receiver
H5C70_RS04900	COG2205	protein histidine kinase activity
H5C70_RS04900	COG3850	Histidine kinase
H5C70_RS04910	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H5C70_RS04915	COG2336	PFAM SpoVT AbrB
H5C70_RS04920	COG2337	Toxic component of a toxin-antitoxin (TA) module
H5C70_RS04925	COG3956	TIGRFAM MazG family protein
H5C70_RS04945	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
H5C70_RS04955	COG0602	queuosine metabolic process
H5C70_RS04960	COG1070	Carbohydrate kinase
H5C70_RS04965	COG0720	synthase
H5C70_RS04990	COG1203	CRISPR-associated helicase, Cas3
H5C70_RS05005	COG1857	crispr-associated protein
H5C70_RS05020	COG1518	maintenance of DNA repeat elements
H5C70_RS05025	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H5C70_RS05030	COG2234	aminopeptidase activity
H5C70_RS05085	COG1388	LysM domain
H5C70_RS05085	COG4942	peptidase
H5C70_RS05090	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H5C70_RS05105	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
H5C70_RS05115	COG2610	gluconate transmembrane transporter activity
H5C70_RS05120	COG3622	Belongs to the hyi family
H5C70_RS05125	COG0235	Class ii aldolase
H5C70_RS05130	COG3395	kinase activity
H5C70_RS05135	COG2084	Dehydrogenase
H5C70_RS05140	COG1349	DNA-binding transcription factor activity
H5C70_RS05145	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H5C70_RS05165	COG3604	Transcriptional regulator
H5C70_RS05170	COG0309	Hydrogenase expression formation protein (HypE)
H5C70_RS05175	COG0409	Hydrogenase expression formation protein
H5C70_RS05180	COG0298	carbon dioxide binding
H5C70_RS05185	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
H5C70_RS05190	COG0375	protein maturation
H5C70_RS05200	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H5C70_RS05205	COG0651	ATP synthesis coupled electron transport
H5C70_RS05210	COG0650	Formate hydrogenlyase subunit 4
H5C70_RS05215	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
H5C70_RS05215	COG3261	NADH dehydrogenase
H5C70_RS05220	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H5C70_RS05225	COG3260	NADH ubiquinone oxidoreductase 20
H5C70_RS05235	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
H5C70_RS05240	COG2723	6-phospho-beta-galactosidase activity
H5C70_RS05245	COG1263	PTS System
H5C70_RS05245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H5C70_RS05250	COG1609	Transcriptional regulator
H5C70_RS05255	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H5C70_RS05260	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
H5C70_RS05285	COG1349	DNA-binding transcription factor activity
H5C70_RS05290	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
H5C70_RS05295	COG1028	Short-chain dehydrogenase reductase Sdr
H5C70_RS05305	COG3732	PTS system glucitol sorbitol-specific
H5C70_RS05310	COG3730	PTS system glucitol sorbitol-specific
H5C70_RS05315	COG2951	lytic endotransglycosylase activity
H5C70_RS05320	COG1546	Belongs to the CinA family
H5C70_RS05340	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
H5C70_RS05370	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H5C70_RS05375	COG1238	metal cluster binding
H5C70_RS05390	COG2814	Major facilitator Superfamily
H5C70_RS05395	COG1566	PFAM secretion protein HlyD family protein
H5C70_RS05400	COG1846	Transcriptional regulator
H5C70_RS05410	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H5C70_RS05415	COG2814	Major facilitator Superfamily
H5C70_RS05420	COG2113	Glycine betaine
H5C70_RS05425	COG4176	ABC-type proline glycine betaine transport system permease component
H5C70_RS05430	COG4175	Glycine betaine
H5C70_RS05435	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H5C70_RS05440	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H5C70_RS05450	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H5C70_RS05455	COG4575	ribosome binding
H5C70_RS05470	COG2916	Histone family protein nucleoid-structuring protein H-NS
H5C70_RS05475	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H5C70_RS05480	COG0640	Transcriptional regulator
H5C70_RS05485	COG0401	homolog of Blt101
H5C70_RS05490	COG1652	LysM domain
H5C70_RS05495	COG1802	Transcriptional regulator
H5C70_RS05500	COG1113	amino acid transport
H5C70_RS05505	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H5C70_RS05510	COG1012	belongs to the aldehyde dehydrogenase family
H5C70_RS05515	COG0579	oxidoreductase
H5C70_RS05575	COG0582	viral genome integration into host DNA
H5C70_RS05590	COG0582	viral genome integration into host DNA
H5C70_RS05610	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
H5C70_RS05615	COG5532	Uncharacterized conserved protein (DUF2303)
H5C70_RS05625	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H5C70_RS05630	COG4197	protein conserved in bacteria, prophage-related
H5C70_RS05650	COG1846	Transcriptional regulator
H5C70_RS05660	COG4725	Belongs to the MT-A70-like family
H5C70_RS05670	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
H5C70_RS05680	COG1403	HNH endonuclease
H5C70_RS05720	COG3772	lysozyme
H5C70_RS05755	COG0740	serine-type endopeptidase activity
H5C70_RS05880	COG2867	negative regulation of translational initiation
H5C70_RS05890	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H5C70_RS05895	COG0497	DNA recombination
H5C70_RS05910	COG4536	flavin adenine dinucleotide binding
H5C70_RS05915	COG4137	Cytochrome C assembly protein
H5C70_RS05920	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H5C70_RS05945	COG2885	chlorophyll binding
H5C70_RS05950	COG2199	diguanylate cyclase activity
H5C70_RS05965	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H5C70_RS05970	COG1605	Chorismate mutase
H5C70_RS05970	COG0287	Prephenate dehydrogenase
H5C70_RS05975	COG0077	Prephenate dehydratase
H5C70_RS05975	COG1605	Chorismate mutase
H5C70_RS05985	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
H5C70_RS05990	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H5C70_RS05995	COG0564	pseudouridine synthase activity
H5C70_RS06000	COG1496	oxidoreductase activity
H5C70_RS06005	COG0542	response to heat
H5C70_RS06030	COG0477	Major facilitator Superfamily
H5C70_RS06035	COG5544	Lipoprotein
H5C70_RS06040	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H5C70_RS06045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H5C70_RS06045	COG1042	CoA-binding domain protein
H5C70_RS06045	COG0045	succinate-CoA ligase (ADP-forming) activity
H5C70_RS06050	COG3148	PFAM DTW domain containing protein
H5C70_RS06055	COG3118	belongs to the thioredoxin family
H5C70_RS06060	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H5C70_RS06080	COG0583	DNA-binding transcription factor activity
H5C70_RS06085	COG0513	Belongs to the DEAD box helicase family
H5C70_RS06095	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
H5C70_RS06105	COG1595	DNA-templated transcription, initiation
H5C70_RS06110	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
H5C70_RS06115	COG3026	antisigma factor binding
H5C70_RS06120	COG3086	response to oxidative stress
H5C70_RS06130	COG0681	Belongs to the peptidase S26 family
H5C70_RS06150	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
H5C70_RS06165	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H5C70_RS06170	COG1737	Transcriptional regulator
H5C70_RS06175	COG0560	Phosphoserine phosphatase
H5C70_RS06195	COG2205	protein histidine kinase activity
H5C70_RS06200	COG3170	Tfp pilus assembly protein FimV
H5C70_RS06205	COG2204	response regulator
H5C70_RS06210	COG0347	Belongs to the P(II) protein family
H5C70_RS06215	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H5C70_RS06215	COG1017	nitric oxide dioxygenase activity
H5C70_RS06225	COG1940	carbohydrate kinase activity
H5C70_RS06235	COG1879	ABC-type sugar transport system periplasmic component
H5C70_RS06240	COG1129	ABC transporter
H5C70_RS06245	COG1172	Belongs to the binding-protein-dependent transport system permease family
H5C70_RS06250	COG1063	alcohol dehydrogenase
H5C70_RS06255	COG2017	converts alpha-aldose to the beta-anomer
H5C70_RS06260	COG2259	Doxx family
H5C70_RS06285	COG4638	Rieske (2fe-2S)
H5C70_RS06290	COG0583	DNA-binding transcription factor activity
H5C70_RS06295	COG2814	Major facilitator Superfamily
H5C70_RS06300	COG3711	transcriptional antiterminator
H5C70_RS06305	COG1073	alpha beta
H5C70_RS06310	COG0483	inositol monophosphate 1-phosphatase activity
H5C70_RS06330	COG0822	iron-sulfur transferase activity
H5C70_RS06350	COG0633	Ferredoxin
H5C70_RS06355	COG2975	iron-sulfur cluster assembly
H5C70_RS06370	COG2897	thiosulfate sulfurtransferase activity
H5C70_RS06375	COG2373	Large extracellular alpha-helical protein
H5C70_RS06380	COG4953	penicillin-binding protein 1C
H5C70_RS06410	COG2976	Protein conserved in bacteria
H5C70_RS06425	COG1645	bacterial-type flagellum-dependent swarming motility
H5C70_RS06435	COG0517	IMP dehydrogenase activity
H5C70_RS06435	COG0516	GMP reductase activity
H5C70_RS06450	COG3133	Outer membrane lipoprotein
H5C70_RS06465	COG2200	EAL domain
H5C70_RS06470	COG0248	Ppx GppA phosphatase
H5C70_RS06475	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
H5C70_RS06480	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H5C70_RS06495	COG2233	PERMEase
H5C70_RS06505	COG1393	Belongs to the ArsC family
H5C70_RS06510	COG4783	chaperone-mediated protein folding
H5C70_RS06515	COG0628	permease
H5C70_RS06540	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H5C70_RS06545	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
H5C70_RS06545	COG3261	NADH dehydrogenase
H5C70_RS06550	COG0651	ATP synthesis coupled electron transport
H5C70_RS06555	COG4237	Hydrogenase 4 membrane
H5C70_RS06565	COG0650	Formate hydrogenlyase subunit 4
H5C70_RS06570	COG0651	ATP synthesis coupled electron transport
H5C70_RS06575	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H5C70_RS06580	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H5C70_RS06585	COG2716	regulation of RNA biosynthetic process
H5C70_RS06595	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
H5C70_RS06615	COG2321	neutral zinc metallopeptidase
H5C70_RS06625	COG0400	carboxylic ester hydrolase activity
H5C70_RS06640	COG1393	Belongs to the ArsC family
H5C70_RS06650	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H5C70_RS06655	COG3850	Histidine kinase
H5C70_RS06660	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H5C70_RS06660	COG0493	'glutamate synthase
H5C70_RS06670	COG5342	invasion associated locus B
H5C70_RS06675	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H5C70_RS06680	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H5C70_RS06685	COG0281	malic enzyme
H5C70_RS06685	COG0280	phosphate acetyltransferase
H5C70_RS06690	COG4810	utilization protein
H5C70_RS06695	COG4917	ethanolamine utilization protein
H5C70_RS06700	COG4766	ethanolamine catabolic process
H5C70_RS06705	COG4812	Cobalamin adenosyltransferase
H5C70_RS06710	COG0280	phosphate acetyltransferase
H5C70_RS06715	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
H5C70_RS06720	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
H5C70_RS06725	COG1012	belongs to the aldehyde dehydrogenase family
H5C70_RS06730	COG4820	ethanolamine utilization protein (EutJ)
H5C70_RS06735	COG1454	alcohol dehydrogenase
H5C70_RS06740	COG3192	ethanolamine utilization protein
H5C70_RS06745	COG4819	ethanolamine utilization protein
H5C70_RS06750	COG4303	Ethanolamine ammonia lyase large subunit
H5C70_RS06760	COG4816	utilization protein
H5C70_RS06765	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
H5C70_RS06770	COG2207	Transcriptional regulator
H5C70_RS06780	COG0860	N-Acetylmuramoyl-L-alanine amidase
H5C70_RS06800	COG2837	iron assimilation
H5C70_RS06805	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H5C70_RS06810	COG1263	PTS System
H5C70_RS06810	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H5C70_RS06825	COG1028	Short-chain dehydrogenase reductase Sdr
H5C70_RS06830	COG4150	thiosulfate binding
H5C70_RS06835	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
H5C70_RS06840	COG4208	sulfate ABC transporter
H5C70_RS06845	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
H5C70_RS06850	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H5C70_RS06865	COG2190	(PTS) system
H5C70_RS06870	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H5C70_RS06875	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H5C70_RS06880	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H5C70_RS06900	COG3530	Putative quorum-sensing-regulated virulence factor
H5C70_RS06905	COG0385	Bile acid
H5C70_RS06910	COG0583	DNA-binding transcription factor activity
H5C70_RS06920	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
H5C70_RS06925	COG2211	Major facilitator Superfamily
H5C70_RS06935	COG0583	DNA-binding transcription factor activity
H5C70_RS06970	COG3415	Transposase
H5C70_RS06975	COG3415	Transposase
H5C70_RS06990	COG2199	diguanylate cyclase activity
H5C70_RS06990	COG2200	EAL domain
H5C70_RS06995	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H5C70_RS07020	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H5C70_RS07025	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H5C70_RS07030	COG0006	proline dipeptidase activity
H5C70_RS07035	COG1363	Peptidase, m42
H5C70_RS07045	COG2207	Transcriptional regulator
H5C70_RS07050	COG3279	Response regulator of the LytR AlgR family
H5C70_RS07055	COG3275	phosphorelay sensor kinase activity
H5C70_RS07060	COG0436	Aminotransferase
H5C70_RS07070	COG1560	Kdo2-lipid A biosynthetic process
H5C70_RS07095	COG0028	Belongs to the TPP enzyme family
H5C70_RS07100	COG0679	Auxin Efflux Carrier
H5C70_RS07105	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H5C70_RS07110	COG2198	Histidine kinase
H5C70_RS07110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H5C70_RS07110	COG0784	Response regulator, receiver
H5C70_RS07110	COG2205	protein histidine kinase activity
H5C70_RS07115	COG2197	response regulator
H5C70_RS07120	COG1566	PFAM secretion protein HlyD family protein
H5C70_RS07125	COG0477	Major facilitator Superfamily
H5C70_RS07165	COG2116	formate transmembrane transporter activity
H5C70_RS07170	COG2853	Lipoprotein
H5C70_RS07180	COG2067	long-chain fatty acid transport protein
H5C70_RS07185	COG3691	Protein conserved in bacteria
H5C70_RS07200	COG2062	phosphohistidine phosphatase, SixA
H5C70_RS07205	COG3539	Fimbrial protein
H5C70_RS07210	COG3188	usher protein
H5C70_RS07215	COG3121	Chaperone
H5C70_RS07220	COG3539	Fimbrial protein
H5C70_RS07225	COG3539	Fimbrial protein
H5C70_RS07230	COG3539	Fimbrial protein
H5C70_RS07260	COG0730	response to heat
H5C70_RS07265	COG3101	peptidyl-lysine hydroxylation
H5C70_RS07280	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H5C70_RS07285	COG2814	Major facilitator Superfamily
H5C70_RS07300	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H5C70_RS07310	COG0586	Pfam SNARE associated Golgi protein
H5C70_RS07320	COG0285	dihydrofolate synthase activity
H5C70_RS07325	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
H5C70_RS07330	COG1286	toxin biosynthetic process
H5C70_RS07335	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
H5C70_RS07340	COG0163	prenyltransferase activity
H5C70_RS07345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H5C70_RS07350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H5C70_RS07355	COG4215	(ABC) transporter
H5C70_RS07360	COG4160	amino acid transport
H5C70_RS07365	COG4598	ABC transporter
H5C70_RS07370	COG5464	transposase or invertase
H5C70_RS07375	COG1090	epimerase
H5C70_RS07380	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
H5C70_RS07385	COG0625	glutathione transferase activity
H5C70_RS07390	COG0625	glutathione transferase activity
H5C70_RS07395	COG0622	Phosphoesterase
H5C70_RS07400	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
H5C70_RS07405	COG1288	antiporter activity
H5C70_RS07410	COG0280	phosphate acetyltransferase
H5C70_RS07410	COG0857	belongs to the CobB CobQ family
H5C70_RS07415	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H5C70_RS07430	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H5C70_RS07435	COG0490	domain, Protein
H5C70_RS07435	COG0471	metal ion transport
H5C70_RS07445	COG0436	Aminotransferase
H5C70_RS07450	COG0583	DNA-binding transcription factor activity
H5C70_RS07470	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
H5C70_RS07475	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
H5C70_RS07480	COG1034	ATP synthesis coupled electron transport
H5C70_RS07495	COG0839	Belongs to the complex I subunit 6 family
H5C70_RS07505	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H5C70_RS07510	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H5C70_RS07540	COG2153	protein acetylation
H5C70_RS07545	COG4575	ribosome binding
H5C70_RS07550	COG1169	isochorismate synthase
H5C70_RS07565	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
H5C70_RS07575	COG0318	PFAM AMP-dependent synthetase and ligase
H5C70_RS07645	COG5464	transposase or invertase
H5C70_RS07650	COG0247	lactate metabolic process
H5C70_RS07660	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
H5C70_RS07665	COG2271	Major facilitator Superfamily
H5C70_RS07670	COG0584	glycerophosphoryl diester phosphodiesterase
H5C70_RS07680	COG3642	lipopolysaccharide core region biosynthetic process
H5C70_RS07685	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H5C70_RS07690	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H5C70_RS07695	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H5C70_RS07710	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H5C70_RS07715	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
H5C70_RS07720	COG3234	Protein of unknown function (DUF1175)
H5C70_RS07725	COG2373	Large extracellular alpha-helical protein
H5C70_RS07730	COG5445	Predicted secreted protein (DUF2300)
H5C70_RS07735	COG4676	Protein conserved in bacteria
H5C70_RS07740	COG0784	Response regulator, receiver
H5C70_RS07740	COG2205	protein histidine kinase activity
H5C70_RS07745	COG2197	response regulator
H5C70_RS07750	COG0642	Histidine kinase
H5C70_RS07750	COG2198	Histidine kinase
H5C70_RS07760	COG1477	protein flavinylation
H5C70_RS07765	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H5C70_RS07765	COG2169	Transcriptional regulator
H5C70_RS07770	COG3145	DNA-N1-methyladenine dioxygenase activity
H5C70_RS07775	COG4615	Cyclic peptide transporter
H5C70_RS07795	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
H5C70_RS07795	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H5C70_RS07800	COG3062	negative regulation of establishment of protein localization
H5C70_RS07810	COG0437	4 iron, 4 sulfur cluster binding
H5C70_RS07815	COG0348	domain, Protein
H5C70_RS07820	COG3043	anaerobic respiration
H5C70_RS07825	COG3005	denitrification pathway
H5C70_RS07830	COG4133	protoheme IX ABC transporter activity
H5C70_RS07835	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H5C70_RS07840	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H5C70_RS07845	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H5C70_RS07855	COG1138	Cytochrome C-type biogenesis protein
H5C70_RS07860	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H5C70_RS07865	COG4235	cytochrome complex assembly
H5C70_RS07865	COG3088	subunit of a heme lyase
H5C70_RS07870	COG2197	response regulator
H5C70_RS07885	COG3083	sulfuric ester hydrolase activity
H5C70_RS07905	COG1061	Type III restriction enzyme res subunit
H5C70_RS07910	COG1187	pseudouridine synthase activity
H5C70_RS07915	COG2814	Major facilitator Superfamily
H5C70_RS07925	COG4172	Belongs to the ABC transporter superfamily
H5C70_RS07930	COG4239	(ABC) transporter, permease
H5C70_RS07935	COG4174	ABC transporter (Permease)
H5C70_RS07940	COG4166	transmembrane transport
H5C70_RS07945	COG2200	EAL domain
H5C70_RS07950	COG0791	NLP P60 protein
H5C70_RS07955	COG0671	phosphoesterase, PA-phosphatase related
H5C70_RS07960	COG0523	cobalamin synthesis protein
H5C70_RS07965	COG0246	Mannitol dehydrogenase
H5C70_RS07980	COG2814	Major facilitator Superfamily
H5C70_RS07985	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H5C70_RS07985	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H5C70_RS07990	COG1105	Belongs to the carbohydrate kinase PfkB family
H5C70_RS07995	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H5C70_RS07995	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
H5C70_RS07995	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H5C70_RS08000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H5C70_RS08005	COG2313	pseudouridylate synthase activity
H5C70_RS08010	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H5C70_RS08015	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H5C70_RS08025	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H5C70_RS08030	COG1522	sequence-specific DNA binding
H5C70_RS08030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H5C70_RS08040	COG2855	membrane
H5C70_RS08045	COG0583	DNA-binding transcription factor activity
H5C70_RS08050	COG0833	amino acid
H5C70_RS08065	COG4771	TonB-dependent receptor
H5C70_RS08080	COG2311	Membrane
H5C70_RS08085	COG1609	Transcriptional regulator
H5C70_RS08090	COG1879	ABC-type sugar transport system periplasmic component
H5C70_RS08095	COG1129	ABC transporter
H5C70_RS08100	COG4211	Belongs to the binding-protein-dependent transport system permease family
H5C70_RS08105	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
H5C70_RS08105	COG0167	dihydroorotate dehydrogenase activity
H5C70_RS08110	COG0493	'glutamate synthase
H5C70_RS08120	COG2949	membrane
H5C70_RS08130	COG1346	cytolysis
H5C70_RS08140	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H5C70_RS08155	COG1028	Short-chain dehydrogenase reductase Sdr
H5C70_RS08160	COG0586	Pfam SNARE associated Golgi protein
H5C70_RS08170	COG1686	Belongs to the peptidase S11 family
H5C70_RS08175	COG0277	FAD linked oxidase domain protein
H5C70_RS08180	COG1472	Belongs to the glycosyl hydrolase 3 family
H5C70_RS08185	COG1732	Glycine betaine
H5C70_RS08190	COG1174	glycine betaine transport
H5C70_RS08195	COG1125	glycine betaine transport
H5C70_RS08200	COG1174	glycine betaine transport
H5C70_RS08215	COG3275	phosphorelay sensor kinase activity
H5C70_RS08220	COG3279	Response regulator of the LytR AlgR family
H5C70_RS08225	COG4807	Protein conserved in bacteria
H5C70_RS08230	COG4808	Protein conserved in bacteria
H5C70_RS08235	COG4715	Zinc finger, swim domain protein
H5C70_RS08240	COG3552	Protein containing von Willebrand factor type A (VWA) domain
H5C70_RS08245	COG2425	protein containing a von Willebrand factor type A (vWA) domain
H5C70_RS08250	COG0714	Associated with various cellular activities
H5C70_RS08260	COG3831	ATPase activity
H5C70_RS08265	COG3831	ATPase activity
H5C70_RS08275	COG0489	protein tyrosine kinase activity
H5C70_RS08285	COG3539	Fimbrial protein
H5C70_RS08290	COG3121	Chaperone
H5C70_RS08295	COG3188	usher protein
H5C70_RS08300	COG3539	Fimbrial protein
H5C70_RS08305	COG5455	response to cobalt ion
H5C70_RS08325	COG0351	phosphomethylpyrimidine kinase
H5C70_RS08330	COG3757	hydrolase, family 25
H5C70_RS08335	COG2188	Transcriptional regulator
H5C70_RS08340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H5C70_RS08345	COG1397	ADP-ribosylglycohydrolase
H5C70_RS08350	COG2211	Major facilitator Superfamily
H5C70_RS08355	COG1830	Aldolase
H5C70_RS08370	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H5C70_RS08375	COG3414	Phosphotransferase system galactitol-specific IIB component
H5C70_RS08380	COG3775	system Galactitol-specific IIC component
H5C70_RS08385	COG1063	alcohol dehydrogenase
H5C70_RS08405	COG0826	peptidase U32
H5C70_RS08415	COG0745	RESPONSE REGULATOR receiver
H5C70_RS08420	COG2205	protein histidine kinase activity
H5C70_RS08455	COG4245	von Willebrand factor, type A
H5C70_RS08460	COG0631	protein serine/threonine phosphatase activity
H5C70_RS08465	COG3779	Protein conserved in bacteria
H5C70_RS08470	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
H5C70_RS08475	COG0443	Heat shock 70 kDa protein
H5C70_RS08480	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
H5C70_RS08490	COG0572	uridine kinase
H5C70_RS08500	COG2982	Protein involved in outer membrane biogenesis
H5C70_RS08505	COG1253	flavin adenine dinucleotide binding
H5C70_RS08565	COG0463	Glycosyl transferase, family 2
H5C70_RS08570	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
H5C70_RS08575	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H5C70_RS08580	COG1051	belongs to the nudix hydrolase family
H5C70_RS08585	COG0297	glycogen (starch) synthase activity
H5C70_RS08640	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H5C70_RS08650	COG0438	transferase activity, transferring glycosyl groups
H5C70_RS08660	COG0140	phosphoribosyl-ATP diphosphatase activity
H5C70_RS08660	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H5C70_RS08675	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H5C70_RS08680	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
H5C70_RS08680	COG0131	Imidazoleglycerol-phosphate dehydratase
H5C70_RS08705	COG2161	toxin-antitoxin pair type II binding
H5C70_RS08710	COG4115	mRNA cleavage
H5C70_RS08715	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H5C70_RS08720	COG0583	DNA-binding transcription factor activity
H5C70_RS08730	COG0531	amino acid
H5C70_RS08735	COG2391	methyltransferase activity
H5C70_RS08740	COG0425	Belongs to the sulfur carrier protein TusA family
H5C70_RS08745	COG2925	Exonuclease
H5C70_RS08750	COG1686	Belongs to the peptidase S11 family
H5C70_RS08760	COG1289	transmembrane transporter activity
H5C70_RS08770	COG4917	ethanolamine utilization protein
H5C70_RS08805	COG2003	Belongs to the UPF0758 family
H5C70_RS08825	COG1484	DNA-dependent DNA replication
H5C70_RS08835	COG3468	outer membrane autotransporter barrel domain protein
H5C70_RS08900	COG4372	Transposase
H5C70_RS08905	COG3436	PFAM IS66 Orf2 family protein
H5C70_RS08925	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
H5C70_RS08940	COG1376	ErfK ybiS ycfS ynhG family protein
H5C70_RS08950	COG0583	DNA-binding transcription factor activity
H5C70_RS08955	COG0583	DNA-binding transcription factor activity
H5C70_RS08965	COG0534	Mate efflux family protein
H5C70_RS08975	COG0217	transcriptional regulatory protein
H5C70_RS08980	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H5C70_RS08985	COG0477	Major facilitator Superfamily
H5C70_RS08995	COG1388	LysM domain
H5C70_RS08995	COG1470	cell adhesion involved in biofilm formation
H5C70_RS09005	COG2373	Large extracellular alpha-helical protein
H5C70_RS09005	COG1388	LysM domain
H5C70_RS09005	COG4932	domain protein
H5C70_RS09010	COG4771	TonB-dependent receptor
H5C70_RS09015	COG1021	2,3-dihydroxybenzoate-AMP ligase
H5C70_RS09035	COG2226	methyltransferase
H5C70_RS09035	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H5C70_RS09035	COG3433	isochorismatase activity
H5C70_RS09050	COG1132	(ABC) transporter
H5C70_RS09060	COG1169	isochorismate synthase
H5C70_RS09065	COG0582	viral genome integration into host DNA
H5C70_RS09085	COG3443	Belongs to the bacterial solute-binding protein 9 family
H5C70_RS09090	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
H5C70_RS09100	COG2351	hydroxyisourate hydrolase activity
H5C70_RS09105	COG0745	RESPONSE REGULATOR receiver
H5C70_RS09110	COG2205	protein histidine kinase activity
H5C70_RS09120	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
H5C70_RS09130	COG1418	mRNA catabolic process
H5C70_RS09135	COG0270	DNA (cytosine-5-)-methyltransferase activity
H5C70_RS09140	COG3727	T/G mismatch-specific endonuclease activity
H5C70_RS09145	COG0697	spore germination
H5C70_RS09150	COG2354	Protein conserved in bacteria
H5C70_RS09155	COG5475	Uncharacterized small protein (DUF2158)
H5C70_RS09180	COG2197	response regulator
H5C70_RS09185	COG1684	flagellar biosynthetic protein fliR
H5C70_RS09190	COG1987	bacterial-type flagellum assembly
H5C70_RS09200	COG3190	flagellar
H5C70_RS09205	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H5C70_RS09210	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H5C70_RS09215	COG1580	Controls the rotational direction of flagella during chemotaxis
H5C70_RS09220	COG3144	bacterial-type flagellum assembly
H5C70_RS09225	COG2882	bacterial-type flagellum organization
H5C70_RS09230	COG1157	protein secretion by the type III secretion system
H5C70_RS09235	COG1317	bacterial-type flagellum organization
H5C70_RS09240	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H5C70_RS09245	COG1766	The M ring may be actively involved in energy transduction
H5C70_RS09255	COG2076	Multidrug Resistance protein
H5C70_RS09260	COG1881	PFAM PEBP family protein
H5C70_RS09265	COG2207	Transcriptional regulator
H5C70_RS09275	COG0675	Transposase, IS605 OrfB family
H5C70_RS09280	COG2135	peptidase activity
H5C70_RS09285	COG0425	Belongs to the sulfur carrier protein TusA family
H5C70_RS09290	COG2391	methyltransferase activity
H5C70_RS09300	COG0366	Alpha amylase catalytic
H5C70_RS09310	COG1516	flagellar protein fliS
H5C70_RS09315	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
H5C70_RS09320	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H5C70_RS09325	COG1191	sigma factor activity
H5C70_RS09335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H5C70_RS09345	COG0765	amino acid transport
H5C70_RS09350	COG1126	abc transporter atp-binding protein
H5C70_RS09355	COG2197	response regulator
H5C70_RS09370	COG2197	response regulator
H5C70_RS09435	COG3318	Belongs to the UPF0149 family
H5C70_RS09435	COG3012	SEC-C Motif Domain Protein
H5C70_RS09440	COG0814	amino acid
H5C70_RS09450	COG1528	Iron-storage protein
H5C70_RS09470	COG1528	Iron-storage protein
H5C70_RS09475	COG1879	ABC-type sugar transport system periplasmic component
H5C70_RS09480	COG1129	ABC transporter
H5C70_RS09485	COG1172	Belongs to the binding-protein-dependent transport system permease family
H5C70_RS09490	COG1877	trehalose-phosphatase activity
H5C70_RS09500	COG0589	response to stress
H5C70_RS09515	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
H5C70_RS09520	COG1360	Flagellar Motor Protein
H5C70_RS09525	COG0643	Histidine kinase
H5C70_RS09525	COG2198	Histidine kinase
H5C70_RS09530	COG0835	chemotaxis
H5C70_RS09535	COG0840	transmembrane signaling receptor activity
H5C70_RS09540	COG0840	transmembrane signaling receptor activity
H5C70_RS09545	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
H5C70_RS09550	COG2201	protein-glutamate methylesterase activity
H5C70_RS09555	COG0745	RESPONSE REGULATOR receiver
H5C70_RS09560	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
H5C70_RS09565	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
H5C70_RS09570	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
H5C70_RS09580	COG3755	Protein conserved in bacteria
H5C70_RS09590	COG3102	Protein conserved in bacteria
H5C70_RS09600	COG3005	denitrification pathway
H5C70_RS09610	COG3547	Transposase (IS116 IS110 IS902 family)
H5C70_RS09625	COG3788	relative of glutathione S-transferase, MAPEG superfamily
H5C70_RS09630	COG1801	Protein of unknown function DUF72
H5C70_RS09635	COG1335	isochorismatase
H5C70_RS09645	COG0494	nUDIX hydrolase
H5C70_RS09650	COG0217	transcriptional regulatory protein
H5C70_RS09680	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H5C70_RS09690	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
H5C70_RS09695	COG0739	heme binding
H5C70_RS09700	COG1560	Kdo2-lipid A biosynthetic process
H5C70_RS09705	COG0469	pyruvate kinase activity
H5C70_RS09710	COG1737	Transcriptional regulator
H5C70_RS09715	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
H5C70_RS09720	COG0129	dihydroxy-acid dehydratase activity
H5C70_RS09725	COG0800	Aldolase
H5C70_RS09735	COG3141	response to X-ray
H5C70_RS09745	COG2979	Protein of unknown function (DUF533)
H5C70_RS09750	COG1770	oligopeptidase
H5C70_RS09755	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H5C70_RS09760	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H5C70_RS09770	COG2372	response to copper ion
H5C70_RS09775	COG1276	copper resistance
H5C70_RS09785	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H5C70_RS09805	COG3008	intermembrane lipid transfer
H5C70_RS09810	COG2995	paraquat-inducible protein a
H5C70_RS09815	COG1956	GAF domain-containing protein
H5C70_RS09825	COG0793	Belongs to the peptidase S41A family
H5C70_RS09835	COG2814	Major facilitator Superfamily
H5C70_RS09840	COG1414	Transcriptional regulator
H5C70_RS09885	COG3716	PTS system mannose fructose sorbose family IID component
H5C70_RS09890	COG3715	PTS system
H5C70_RS09895	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
H5C70_RS09895	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H5C70_RS09900	COG1253	flavin adenine dinucleotide binding
H5C70_RS09905	COG2200	EAL domain
H5C70_RS09910	COG1760	l-serine dehydratase
H5C70_RS09920	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H5C70_RS09935	COG0251	oxidation-reduction process
H5C70_RS09940	COG1199	ATP-dependent helicase activity
H5C70_RS09945	COG1214	PFAM Peptidase M22, glycoprotease
H5C70_RS09950	COG3065	identical protein binding
H5C70_RS09955	COG0318	PFAM AMP-dependent synthetase and ligase
H5C70_RS09960	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
H5C70_RS09965	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H5C70_RS09970	COG4638	Rieske (2fe-2S)
H5C70_RS09975	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H5C70_RS09980	COG0473	3-isopropylmalate dehydrogenase activity
H5C70_RS09985	COG0583	DNA-binding transcription factor activity
H5C70_RS10005	COG2261	transglycosylase associated protein
H5C70_RS10020	COG2203	Gaf domain
H5C70_RS10020	COG2199	diguanylate cyclase activity
H5C70_RS10025	COG3042	response to heat
H5C70_RS10030	COG3189	MarR family transcriptional regulator
H5C70_RS10035	COG2807	transmembrane transport
H5C70_RS10040	COG2207	Transcriptional regulator
H5C70_RS10055	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H5C70_RS10060	COG2199	diguanylate cyclase activity
H5C70_RS10065	COG2199	diguanylate cyclase activity
H5C70_RS10075	COG2766	serine protein kinase
H5C70_RS10080	COG3713	MltA-interacting MipA family protein
H5C70_RS10085	COG0656	L-ascorbic acid biosynthetic process
H5C70_RS10090	COG0676	glucose-6-phosphate 1-epimerase activity
H5C70_RS10095	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H5C70_RS10105	COG3139	Protein of unknown function (DUF1315)
H5C70_RS10110	COG1335	isochorismatase
H5C70_RS10115	COG0252	asparaginase activity
H5C70_RS10120	COG0616	signal peptide processing
H5C70_RS10125	COG0778	Nitroreductase
H5C70_RS10135	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H5C70_RS10145	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H5C70_RS10155	COG0494	nUDIX hydrolase
H5C70_RS10160	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H5C70_RS10165	COG2897	thiosulfate sulfurtransferase activity
H5C70_RS10170	COG4136	ATPase activity
H5C70_RS10175	COG4135	transport system, permease component
H5C70_RS10180	COG4134	Bacterial extracellular solute-binding protein
H5C70_RS10185	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H5C70_RS10190	COG0398	Pfam SNARE associated Golgi protein
H5C70_RS10200	COG0398	Pfam SNARE associated Golgi protein
H5C70_RS10205	COG0708	Exodeoxyribonuclease III
H5C70_RS10235	COG3678	ATP-independent chaperone mediated protein folding
H5C70_RS10245	COG0322	excinuclease ABC activity
H5C70_RS10255	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H5C70_RS10260	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H5C70_RS10265	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H5C70_RS10270	COG1447	Phosphotransferase system cellobiose-specific component IIA
H5C70_RS10275	COG2169	Transcriptional regulator
H5C70_RS10275	COG1917	Cupin 2, conserved barrel domain protein
H5C70_RS10280	COG1486	melibiose metabolic process
H5C70_RS10290	COG0753	catalase activity
H5C70_RS10310	COG1823	symporter activity
H5C70_RS10315	COG1988	membrane-bound metal-dependent
H5C70_RS10320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H5C70_RS10330	COG3001	Fructosamine kinase
H5C70_RS10340	COG1105	Belongs to the carbohydrate kinase PfkB family
H5C70_RS10345	COG3137	Salt-induced outer membrane protein
H5C70_RS10405	COG0386	Belongs to the glutathione peroxidase family
H5C70_RS10415	COG0791	NLP P60 protein
H5C70_RS10420	COG2200	EAL domain
H5C70_RS10430	COG4256	Hemin uptake protein
H5C70_RS10435	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H5C70_RS10445	COG0574	Belongs to the PEP-utilizing enzyme family
H5C70_RS10445	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H5C70_RS10450	COG0318	PFAM AMP-dependent synthetase and ligase
H5C70_RS10455	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
H5C70_RS10460	COG0644	oxidoreductase
H5C70_RS10465	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
H5C70_RS10470	COG2086	electron transfer activity
H5C70_RS10475	COG2207	Transcriptional regulator
H5C70_RS10475	COG1917	Cupin 2, conserved barrel domain protein
H5C70_RS10480	COG1960	acyl-CoA dehydrogenase activity
H5C70_RS10485	COG4670	ketone body catabolic process
H5C70_RS10500	COG2271	Major facilitator Superfamily
H5C70_RS10505	COG0738	Major facilitator superfamily
H5C70_RS10520	COG0628	permease
H5C70_RS10525	COG0247	lactate metabolic process
H5C70_RS10525	COG0277	FAD linked oxidase domain protein
H5C70_RS10530	COG2050	protein possibly involved in aromatic compounds catabolism
H5C70_RS10540	COG0316	Belongs to the HesB IscA family
H5C70_RS10545	COG0719	Fe-S assembly protein
H5C70_RS10550	COG0396	ATPase activity
H5C70_RS10555	COG0719	Fe-S assembly protein
H5C70_RS10570	COG1376	ErfK ybiS ycfS ynhG family protein
H5C70_RS10575	COG4238	major outer membrane lipoprotein
H5C70_RS10580	COG0469	pyruvate kinase activity
H5C70_RS10590	COG0437	4 iron, 4 sulfur cluster binding
H5C70_RS10595	COG2414	aldehyde ferredoxin oxidoreductase
H5C70_RS10605	COG0437	4 iron, 4 sulfur cluster binding
H5C70_RS10610	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
H5C70_RS10620	COG4529	Protein conserved in bacteria
H5C70_RS10640	COG3468	outer membrane autotransporter barrel domain protein
H5C70_RS10650	COG0307	riboflavin synthase, alpha
H5C70_RS10655	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H5C70_RS10660	COG2814	Major facilitator Superfamily
H5C70_RS10665	COG0583	DNA-binding transcription factor activity
H5C70_RS10680	COG2814	Major facilitator Superfamily
H5C70_RS10685	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H5C70_RS10690	COG0791	NLP P60 protein
H5C70_RS10695	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H5C70_RS10700	COG1201	RNA secondary structure unwinding
H5C70_RS10710	COG0346	lactoylglutathione lyase activity
H5C70_RS10715	COG1902	pentaerythritol trinitrate reductase activity
H5C70_RS10720	COG1309	transcriptional regulator
H5C70_RS10725	COG3313	Fe-S protein
H5C70_RS10730	COG4989	oxidoreductase activity
H5C70_RS10735	COG2032	superoxide dismutase activity
H5C70_RS10740	COG1289	transmembrane transporter activity
H5C70_RS10745	COG1566	PFAM secretion protein HlyD family protein
H5C70_RS10760	COG3133	Outer membrane lipoprotein
H5C70_RS10770	COG3895	Periplasmic Protein
H5C70_RS10785	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
H5C70_RS10790	COG0625	glutathione transferase activity
H5C70_RS10795	COG3104	oligopeptide transport
H5C70_RS10800	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H5C70_RS10810	COG4659	FMN binding
H5C70_RS10850	COG0673	inositol 2-dehydrogenase activity
H5C70_RS10860	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
H5C70_RS10865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H5C70_RS10865	COG1263	PTS System
H5C70_RS10870	COG1609	Transcriptional regulator
H5C70_RS10875	COG1028	Short-chain dehydrogenase reductase Sdr
H5C70_RS10880	COG1309	transcriptional regulator
H5C70_RS10885	COG3250	beta-galactosidase activity
H5C70_RS10900	COG5339	Protein conserved in bacteria
H5C70_RS10905	COG1482	cell wall glycoprotein biosynthetic process
H5C70_RS10910	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
H5C70_RS10910	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H5C70_RS10915	COG0114	fumarate hydratase activity
H5C70_RS10925	COG2205	protein histidine kinase activity
H5C70_RS10930	COG0745	RESPONSE REGULATOR receiver
H5C70_RS10935	COG3136	membrane protein required for alginate biosynthesis
H5C70_RS10945	COG0531	amino acid
H5C70_RS10955	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
H5C70_RS10960	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
H5C70_RS10965	COG0628	permease
H5C70_RS10980	COG3591	Belongs to the peptidase S1B family
H5C70_RS10995	COG2814	Major facilitator Superfamily
H5C70_RS11000	COG0583	DNA-binding transcription factor activity
H5C70_RS11005	COG1940	carbohydrate kinase activity
H5C70_RS11010	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
H5C70_RS11020	COG3381	protein complex oligomerization
H5C70_RS11025	COG3302	dmso reductase anchor subunit
H5C70_RS11030	COG0437	4 iron, 4 sulfur cluster binding
H5C70_RS11035	COG0243	molybdopterin cofactor binding
H5C70_RS11040	COG0243	molybdopterin cofactor binding
H5C70_RS11055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H5C70_RS11070	COG4948	Mandelate Racemase Muconate Lactonizing
H5C70_RS11075	COG1063	alcohol dehydrogenase
H5C70_RS11080	COG0477	Major facilitator Superfamily
H5C70_RS11095	COG1802	Transcriptional regulator
H5C70_RS11100	COG4221	oxidoreductase activity
H5C70_RS11105	COG0339	signal peptide processing
H5C70_RS11110	COG1546	Belongs to the CinA family
H5C70_RS11115	COG3111	PFAM Bacterial OB fold (BOF) protein
H5C70_RS11120	COG3706	GGDEF domain
H5C70_RS11130	COG2814	Major facilitator Superfamily
H5C70_RS11135	COG0697	spore germination
H5C70_RS11140	COG2188	Transcriptional regulator
H5C70_RS11150	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H5C70_RS11155	COG1447	Phosphotransferase system cellobiose-specific component IIA
H5C70_RS11165	COG2723	6-phospho-beta-galactosidase activity
H5C70_RS11175	COG4977	sequence-specific DNA binding
H5C70_RS11180	COG1846	Transcriptional regulator
H5C70_RS11200	COG0583	DNA-binding transcription factor activity
H5C70_RS11205	COG1012	belongs to the aldehyde dehydrogenase family
H5C70_RS11210	COG2066	Belongs to the glutaminase family
H5C70_RS11220	COG2199	diguanylate cyclase activity
H5C70_RS11230	COG3781	membrane
H5C70_RS11280	COG2911	Protein conserved in bacteria
H5C70_RS11280	COG3210	domain, Protein
H5C70_RS11285	COG1396	sequence-specific DNA binding
H5C70_RS11290	COG3550	peptidyl-serine autophosphorylation
H5C70_RS11300	COG3539	Fimbrial protein
H5C70_RS11310	COG3188	usher protein
H5C70_RS11315	COG3539	Fimbrial protein
H5C70_RS11320	COG3539	Fimbrial protein
H5C70_RS11325	COG3539	Fimbrial protein
H5C70_RS11330	COG0243	molybdopterin cofactor binding
H5C70_RS11345	COG3119	arylsulfatase activity
H5C70_RS11350	COG0641	radical SAM
H5C70_RS11360	COG4178	(ABC) transporter
H5C70_RS11365	COG4771	TonB-dependent receptor
H5C70_RS11370	COG0612	Peptidase, M16
H5C70_RS11375	COG0076	glutamate decarboxylase activity
H5C70_RS11380	COG0531	amino acid
H5C70_RS11385	COG1649	PFAM Uncharacterised BCR, COG1649
H5C70_RS11395	COG2202	Pas domain
H5C70_RS11395	COG2199	diguanylate cyclase activity
H5C70_RS11395	COG2200	EAL domain
H5C70_RS11400	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
H5C70_RS11405	COG0747	negative chemotaxis
H5C70_RS11410	COG0601	transmembrane transport
H5C70_RS11415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H5C70_RS11420	COG0444	Belongs to the ABC transporter superfamily
H5C70_RS11425	COG4608	Belongs to the ABC transporter superfamily
H5C70_RS11430	COG1764	response to oxidative stress
H5C70_RS11450	COG1064	alcohol dehydrogenase
H5C70_RS11455	COG3093	addiction module antidote protein HigA
H5C70_RS11460	COG2864	formate dehydrogenase
H5C70_RS11465	COG0437	4 iron, 4 sulfur cluster binding
H5C70_RS11475	COG0697	spore germination
H5C70_RS11480	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
H5C70_RS11485	COG4886	Leucine-rich repeat (LRR) protein
H5C70_RS11490	COG2223	nitrite transmembrane transporter activity
H5C70_RS11495	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
H5C70_RS11500	COG1140	nitrate reductase beta subunit
H5C70_RS11505	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
H5C70_RS11510	COG2181	nitrate reductase activity
H5C70_RS11515	COG0384	phenazine biosynthesis protein PhzF
H5C70_RS11520	COG2162	N-hydroxyarylamine O-acetyltransferase activity
H5C70_RS11525	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H5C70_RS11545	COG3209	COG3209 Rhs family protein
H5C70_RS11565	COG3209	COG3209 Rhs family protein
H5C70_RS11580	COG3209	COG3209 Rhs family protein
H5C70_RS11615	COG3209	COG3209 Rhs family protein
H5C70_RS11630	COG0625	glutathione transferase activity
H5C70_RS11635	COG1113	amino acid transport
H5C70_RS11640	COG3391	amine dehydrogenase activity
H5C70_RS11645	COG4772	TonB-dependent receptor
H5C70_RS11650	COG1802	Transcriptional regulator
H5C70_RS11655	COG2130	NADP-dependent
H5C70_RS11660	COG1247	-acetyltransferase
H5C70_RS11665	COG3238	Protein conserved in bacteria
H5C70_RS11690	COG1177	transmembrane transport
H5C70_RS11695	COG1176	ABC-type spermidine putrescine transport system, permease component I
H5C70_RS11715	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
H5C70_RS11720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H5C70_RS11725	COG1598	PFAM Uncharacterised protein family UPF0150
H5C70_RS11730	COG1724	mRNA binding
H5C70_RS11740	COG0826	peptidase U32
H5C70_RS11745	COG1396	sequence-specific DNA binding
H5C70_RS11750	COG3135	benzoate transporter
H5C70_RS11755	COG0675	Transposase, IS605 OrfB family
H5C70_RS11770	COG0500	methyltransferase
H5C70_RS11775	COG1275	C4-dicarboxylate transporter malic acid transport protein
H5C70_RS11780	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H5C70_RS11785	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H5C70_RS11790	COG2841	Protein conserved in bacteria
H5C70_RS11800	COG5383	Protein conserved in bacteria
H5C70_RS11805	COG0583	DNA-binding transcription factor activity
H5C70_RS11810	COG0840	transmembrane signaling receptor activity
H5C70_RS11825	COG3038	cytochrome b561
H5C70_RS11830	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H5C70_RS11835	COG1012	belongs to the aldehyde dehydrogenase family
H5C70_RS11840	COG1434	Gram-negative-bacterium-type cell wall biogenesis
H5C70_RS11845	COG1643	Atp-dependent helicase
H5C70_RS11855	COG0671	phosphoesterase, PA-phosphatase related
H5C70_RS11855	COG2453	phosphatase
H5C70_RS11860	COG2267	carboxylic ester hydrolase activity
H5C70_RS11865	COG4589	Belongs to the CDS family
H5C70_RS11870	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H5C70_RS11880	COG0667	Aldo Keto reductase
H5C70_RS11885	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H5C70_RS11890	COG3327	negative regulation of DNA-templated transcription, initiation
H5C70_RS11895	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
H5C70_RS11900	COG0183	Belongs to the thiolase family
H5C70_RS11905	COG2050	protein possibly involved in aromatic compounds catabolism
H5C70_RS11910	COG1250	3-hydroxyacyl-CoA dehydrogenase
H5C70_RS11915	COG1024	Enoyl-CoA hydratase
H5C70_RS11920	COG1024	Enoyl-CoA hydratase
H5C70_RS11925	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H5C70_RS11930	COG2151	metal-sulfur cluster biosynthetic enzyme
H5C70_RS11935	COG3396	Phenylacetate-CoA oxygenase
H5C70_RS11940	COG3460	Phenylacetate-CoA oxygenase
H5C70_RS11945	COG3396	Phenylacetate-CoA oxygenase
H5C70_RS11950	COG2030	dehydratase
H5C70_RS11950	COG1012	belongs to the aldehyde dehydrogenase family
H5C70_RS11955	COG3733	amine oxidase
H5C70_RS11960	COG1012	belongs to the aldehyde dehydrogenase family
H5C70_RS11965	COG2207	Transcriptional regulator
H5C70_RS11970	COG3784	Protein of unknown function (DUF1318)
H5C70_RS11980	COG2911	Protein conserved in bacteria
H5C70_RS11985	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H5C70_RS11990	COG3187	Heat shock protein
H5C70_RS11995	COG3042	response to heat
H5C70_RS12000	COG0674	pyruvate-flavodoxin oxidoreductase activity
H5C70_RS12000	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H5C70_RS12000	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
H5C70_RS12000	COG1013	pyruvate-flavodoxin oxidoreductase activity
H5C70_RS12005	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
H5C70_RS12010	COG0589	response to stress
H5C70_RS12020	COG0513	Belongs to the DEAD box helicase family
H5C70_RS12030	COG3706	GGDEF domain
H5C70_RS12035	COG2840	Smr protein MutS2
H5C70_RS12040	COG0583	DNA-binding transcription factor activity
H5C70_RS12045	COG1473	amidohydrolase
H5C70_RS12050	COG1473	amidohydrolase
H5C70_RS12055	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
H5C70_RS12060	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H5C70_RS12065	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H5C70_RS12070	COG0589	response to stress
H5C70_RS12075	COG3182	Iron-regulated membrane protein
H5C70_RS12080	COG0668	transmembrane transport
H5C70_RS12085	COG4166	transmembrane transport
H5C70_RS12090	COG0583	DNA-binding transcription factor activity
H5C70_RS12095	COG1073	alpha beta
H5C70_RS12110	COG2866	Carboxypeptidase
H5C70_RS12115	COG4948	Mandelate Racemase Muconate Lactonizing
H5C70_RS12120	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
H5C70_RS12125	COG3283	Transcriptional regulator of aromatic amino acids metabolism
H5C70_RS12135	COG3106	COG3106 Predicted ATPase
H5C70_RS12140	COG1609	Transcriptional regulator
H5C70_RS12150	COG3842	ATPase activity
H5C70_RS12155	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H5C70_RS12160	COG1554	hydrolase, family 65, central catalytic
H5C70_RS12165	COG0673	inositol 2-dehydrogenase activity
H5C70_RS12170	COG1082	Xylose isomerase domain protein TIM barrel
H5C70_RS12175	COG1063	alcohol dehydrogenase
H5C70_RS12180	COG0395	ABC-type sugar transport system, permease component
H5C70_RS12185	COG1175	transmembrane transport
H5C70_RS12190	COG1653	transport
H5C70_RS12195	COG0366	Alpha amylase catalytic
H5C70_RS12200	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H5C70_RS12210	COG1983	PspC domain protein
H5C70_RS12220	COG1842	Phage shock protein A
H5C70_RS12225	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
H5C70_RS12230	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H5C70_RS12235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H5C70_RS12240	COG1012	belongs to the aldehyde dehydrogenase family
H5C70_RS12245	COG1396	sequence-specific DNA binding
H5C70_RS12245	COG1917	Cupin 2, conserved barrel domain protein
H5C70_RS12250	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
H5C70_RS12255	COG0174	glutamine synthetase
H5C70_RS12265	COG0531	amino acid
H5C70_RS12275	COG4166	transmembrane transport
H5C70_RS12280	COG4168	peptide transport system, permease
H5C70_RS12285	COG4171	peptide transport system, permease
H5C70_RS12290	COG4172	Belongs to the ABC transporter superfamily
H5C70_RS12295	COG4172	Belongs to the ABC transporter superfamily
H5C70_RS12300	COG2852	Protein conserved in bacteria
H5C70_RS12305	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
H5C70_RS12310	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H5C70_RS12310	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H5C70_RS12325	COG5001	Diguanylate cyclase
H5C70_RS12335	COG1349	DNA-binding transcription factor activity
H5C70_RS12345	COG0023	Translation Initiation Factor
H5C70_RS12355	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
H5C70_RS12360	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
H5C70_RS12365	COG0671	phosphoesterase, PA-phosphatase related
H5C70_RS12375	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H5C70_RS12400	COG0583	DNA-binding transcription factor activity
H5C70_RS12405	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H5C70_RS12415	COG0616	signal peptide processing
H5C70_RS12420	COG1028	Short-chain dehydrogenase reductase Sdr
H5C70_RS12425	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
H5C70_RS12430	COG1187	pseudouridine synthase activity
H5C70_RS12435	COG0009	L-threonylcarbamoyladenylate synthase
H5C70_RS12440	COG0613	PHP domain protein
H5C70_RS12450	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H5C70_RS12455	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H5C70_RS12455	COG0512	Glutamine amidotransferase of anthranilate synthase
H5C70_RS12460	COG0135	phosphoribosylanthranilate isomerase activity
H5C70_RS12460	COG0134	indole-3-glycerol-phosphate synthase activity
H5C70_RS12475	COG3729	General stress protein
H5C70_RS12480	COG3685	Protein conserved in bacteria
H5C70_RS12485	COG3685	Protein conserved in bacteria
H5C70_RS12490	COG3047	cAMP biosynthetic process
H5C70_RS12510	COG1607	acyl-coa hydrolase
H5C70_RS12515	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
H5C70_RS12520	COG2350	Protein conserved in bacteria
H5C70_RS12525	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H5C70_RS12545	COG4608	Belongs to the ABC transporter superfamily
H5C70_RS12550	COG0444	Belongs to the ABC transporter superfamily
H5C70_RS12555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H5C70_RS12560	COG0601	transmembrane transport
H5C70_RS12565	COG4166	transmembrane transport
H5C70_RS12570	COG2095	MarC family integral membrane protein
H5C70_RS12575	COG1454	alcohol dehydrogenase
H5C70_RS12575	COG1012	belongs to the aldehyde dehydrogenase family
H5C70_RS12580	COG1435	thymidine kinase activity
H5C70_RS12590	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H5C70_RS12595	COG0745	RESPONSE REGULATOR receiver
H5C70_RS12600	COG1752	Esterase of the alpha-beta hydrolase superfamily
H5C70_RS12610	COG0788	formyltetrahydrofolate deformylase activity
H5C70_RS12630	COG2181	nitrate reductase activity
H5C70_RS12635	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
H5C70_RS12640	COG1140	nitrate reductase beta subunit
H5C70_RS12645	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
H5C70_RS12650	COG2223	nitrite transmembrane transporter activity
H5C70_RS12655	COG3850	Histidine kinase
H5C70_RS12660	COG2197	response regulator
H5C70_RS12665	COG4932	domain protein
H5C70_RS12670	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
H5C70_RS12675	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
H5C70_RS12680	COG4572	Cation transport regulator
H5C70_RS12685	COG0387	Pfam Sodium calcium exchanger
H5C70_RS12710	COG2912	Transglutaminase-like superfamily
H5C70_RS12715	COG3094	Invasion gene expression up-regulator, SirB
H5C70_RS12720	COG2890	protein-(glutamine-N5) methyltransferase activity
H5C70_RS12745	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H5C70_RS12750	COG0659	secondary active sulfate transmembrane transporter activity
H5C70_RS12765	COG0012	GTP binding
H5C70_RS12770	COG3468	outer membrane autotransporter barrel domain protein
H5C70_RS12775	COG3284	Transcriptional regulator
H5C70_RS12780	COG2376	Dihydroxyacetone kinase
H5C70_RS12785	COG1461	Dihydroxyacetone kinase
H5C70_RS12790	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H5C70_RS12790	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
H5C70_RS12790	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H5C70_RS12810	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
H5C70_RS12820	COG1619	proteins homologs of microcin C7 resistance protein MccF
H5C70_RS12830	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H5C70_RS12840	COG2719	SpoVR family
H5C70_RS12855	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
H5C70_RS12860	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H5C70_RS12865	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H5C70_RS12880	COG0179	Fumarylacetoacetate (FAA) hydrolase
H5C70_RS12905	COG2894	cell division
H5C70_RS12960	COG2200	EAL domain
H5C70_RS12975	COG5562	phage envelope protein
H5C70_RS12995	COG0538	isocitrate dehydrogenase activity
H5C70_RS13025	COG3778	Protein conserved in bacteria
H5C70_RS13030	COG3299	homolog of phage Mu protein gp47
H5C70_RS13050	COG4228	DNA circulation
H5C70_RS13070	COG4386	tail sheath protein
H5C70_RS13115	COG4695	Portal protein
H5C70_RS13125	COG4626	Terminase
H5C70_RS13125	COG1802	Transcriptional regulator
H5C70_RS13170	COG1403	HNH endonuclease
H5C70_RS13180	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
H5C70_RS13190	COG4725	Belongs to the MT-A70-like family
H5C70_RS13200	COG1846	Transcriptional regulator
H5C70_RS13220	COG4197	protein conserved in bacteria, prophage-related
H5C70_RS13225	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H5C70_RS13250	COG5532	Uncharacterized conserved protein (DUF2303)
H5C70_RS13255	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
H5C70_RS13265	COG0582	viral genome integration into host DNA
H5C70_RS13290	COG0538	isocitrate dehydrogenase activity
H5C70_RS13295	COG1187	pseudouridine synthase activity
H5C70_RS13315	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H5C70_RS13325	COG2205	protein histidine kinase activity
H5C70_RS13330	COG2850	peptidyl-arginine hydroxylation
H5C70_RS13340	COG3842	ATPase activity
H5C70_RS13350	COG1177	transmembrane transport
H5C70_RS13355	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
H5C70_RS13365	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
H5C70_RS13370	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
H5C70_RS13375	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H5C70_RS13385	COG4591	ABC-type transport system involved in lipoprotein release permease component
H5C70_RS13390	COG1136	(ABC) transporter
H5C70_RS13395	COG4591	ABC-type transport system involved in lipoprotein release permease component
H5C70_RS13400	COG4763	Acyl-transferase
H5C70_RS13405	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H5C70_RS13410	COG1388	LysM domain
H5C70_RS13410	COG1376	ErfK ybiS ycfS ynhG family protein
H5C70_RS13420	COG1309	transcriptional regulator
H5C70_RS13425	COG3134	Outer membrane lipoprotein
H5C70_RS13430	COG1252	NADH dehydrogenase
H5C70_RS13450	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
H5C70_RS13455	COG5633	Lipoprotein
H5C70_RS13460	COG0537	adenosine 5'-monophosphoramidase activity
H5C70_RS13465	COG4773	Receptor
H5C70_RS13470	COG1263	PTS System
H5C70_RS13470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H5C70_RS13475	COG0084	hydrolase, TatD family'
H5C70_RS13480	COG0470	DNA polymerase III
H5C70_RS13490	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H5C70_RS13495	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H5C70_RS13500	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H5C70_RS13510	COG1028	Short-chain dehydrogenase reductase Sdr
H5C70_RS13515	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H5C70_RS13535	COG1399	metal-binding, possibly nucleic acid-binding protein
H5C70_RS13540	COG0424	maF-like protein
H5C70_RS13545	COG0564	pseudouridine synthase activity
H5C70_RS13550	COG1530	ribonuclease E activity
H5C70_RS13555	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H5C70_RS13560	COG1256	bacterial-type flagellum assembly
H5C70_RS13565	COG1705	Flagellar rod assembly protein muramidase FlgJ
H5C70_RS13565	COG3951	Flagellar rod assembly protein muramidase FlgJ
H5C70_RS13580	COG4786	Flagellar basal body rod
H5C70_RS13585	COG4787	bacterial-type flagellum-dependent cell motility
H5C70_RS13590	COG1749	Flagellar hook protein flgE
H5C70_RS13595	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
H5C70_RS13600	COG1558	bacterial-type flagellum-dependent cell motility
H5C70_RS13605	COG1815	bacterial-type flagellum-dependent cell motility
H5C70_RS13610	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
H5C70_RS13615	COG2747	anti-sigma28 factor FlgM
H5C70_RS13620	COG3418	PFAM FlgN family protein
H5C70_RS13625	COG0728	peptidoglycan biosynthetic process
H5C70_RS13630	COG0673	inositol 2-dehydrogenase activity
H5C70_RS13640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H5C70_RS13650	COG2999	glutathione oxidoreductase activity
H5C70_RS13685	COG3038	cytochrome b561
H5C70_RS13690	COG2353	YceI-like domain
H5C70_RS13700	COG1560	Kdo2-lipid A biosynthetic process
H5C70_RS13715	COG5645	(Lipo)protein
H5C70_RS13720	COG2943	transferase activity, transferring hexosyl groups
H5C70_RS13735	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H5C70_RS13740	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
H5C70_RS13765	COG2197	response regulator
H5C70_RS13780	COG1462	curli production assembly transport component CsgG
H5C70_RS13790	COG3381	protein complex oligomerization
H5C70_RS13825	COG3706	GGDEF domain
H5C70_RS13830	COG0457	Tetratricopeptide repeat
H5C70_RS13835	COG1649	PFAM Uncharacterised BCR, COG1649
H5C70_RS13835	COG0726	polysaccharide deacetylase
H5C70_RS13840	COG1215	transferase activity, transferring glycosyl groups
H5C70_RS13845	COG3658	cytochrome
H5C70_RS13850	COG1702	phosphate starvation-inducible protein PhoH
H5C70_RS13860	COG2822	iron ion transport
H5C70_RS13870	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H5C70_RS13880	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H5C70_RS13880	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H5C70_RS13880	COG0506	proline dehydrogenase activity
H5C70_RS13885	COG1309	transcriptional regulator
H5C70_RS13920	COG2233	PERMEase
H5C70_RS13925	COG3729	General stress protein
H5C70_RS13965	COG0243	molybdopterin cofactor binding
H5C70_RS13970	COG3005	denitrification pathway
H5C70_RS13975	COG0745	RESPONSE REGULATOR receiver
H5C70_RS13980	COG1879	ABC-type sugar transport system periplasmic component
H5C70_RS13985	COG2205	protein histidine kinase activity
H5C70_RS13985	COG2198	Histidine kinase
H5C70_RS13985	COG0784	Response regulator, receiver
H5C70_RS13990	COG0348	domain, Protein
H5C70_RS14010	COG1278	Cold shock
H5C70_RS14015	COG1278	Cold shock
H5C70_RS14035	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H5C70_RS14040	COG1596	polysaccharide export
H5C70_RS14045	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H5C70_RS14050	COG0489	protein tyrosine kinase activity
H5C70_RS14050	COG3206	protein involved in exopolysaccharide biosynthesis
H5C70_RS14065	COG1294	oxidase, subunit
H5C70_RS14070	COG1271	oxidase subunit
H5C70_RS14075	COG1773	rubredoxin
H5C70_RS14080	COG1999	signal sequence binding
H5C70_RS14085	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
H5C70_RS14090	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
H5C70_RS14095	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
H5C70_RS14100	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
H5C70_RS14110	COG0670	Belongs to the BI1 family
H5C70_RS14115	COG2920	part of a sulfur-relay system
H5C70_RS14120	COG1254	Belongs to the acylphosphatase family
H5C70_RS14135	COG1832	CoA-binding protein
H5C70_RS14150	COG0210	DNA helicase
H5C70_RS14155	COG3304	Inner membrane component domain
H5C70_RS14160	COG1289	transmembrane transporter activity
H5C70_RS14165	COG3070	regulator of competence-specific genes
H5C70_RS14185	COG1067	ATP-dependent peptidase activity
H5C70_RS14195	COG3130	regulation of translation
H5C70_RS14200	COG3009	Protein conserved in bacteria
H5C70_RS14205	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H5C70_RS14205	COG3008	intermembrane lipid transfer
H5C70_RS14210	COG2995	paraquat-inducible protein a
H5C70_RS14215	COG0488	(ABC) transporter
H5C70_RS14225	COG3217	Mosc domain protein beta barrel domain protein
H5C70_RS14225	COG0633	Ferredoxin
H5C70_RS14240	COG3121	Chaperone
H5C70_RS14245	COG3539	Fimbrial protein
H5C70_RS14250	COG3539	Fimbrial protein
H5C70_RS14255	COG3539	Fimbrial protein
H5C70_RS14260	COG3188	usher protein
H5C70_RS14265	COG3121	Chaperone
H5C70_RS14270	COG3539	Fimbrial protein
H5C70_RS14275	COG0431	NADPH-dependent FMN reductase
H5C70_RS14280	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H5C70_RS14290	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H5C70_RS14300	COG0308	aminopeptidase N
H5C70_RS14320	COG1448	Aminotransferase
H5C70_RS14325	COG3547	Transposase (IS116 IS110 IS902 family)
H5C70_RS14330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H5C70_RS14335	COG3108	Peptidase M15
H5C70_RS14340	COG2989	Protein conserved in bacteria
H5C70_RS14350	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
H5C70_RS14360	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H5C70_RS14365	COG1434	Gram-negative-bacterium-type cell wall biogenesis
H5C70_RS14370	COG3173	Aminoglycoside phosphotransferase
H5C70_RS14385	COG3214	Protein conserved in bacteria
H5C70_RS14395	COG1132	(ABC) transporter
H5C70_RS14400	COG2333	competence protein COMEC
H5C70_RS14400	COG0658	competence protein
H5C70_RS14410	COG0539	negative regulation of cytoplasmic translation
H5C70_RS14420	COG0501	Belongs to the peptidase M48B family
H5C70_RS14435	COG2323	membrane
H5C70_RS14440	COG1944	ATP diphosphatase activity
H5C70_RS14445	COG2116	formate transmembrane transporter activity
H5C70_RS14450	COG1882	Formate acetyltransferase
H5C70_RS14455	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H5C70_RS14460	COG2249	NAD(P)H dehydrogenase (quinone) activity
H5C70_RS14465	COG0583	DNA-binding transcription factor activity
H5C70_RS14470	COG0531	amino acid
H5C70_RS14480	COG1335	isochorismatase
H5C70_RS14485	COG3302	dmso reductase anchor subunit
H5C70_RS14490	COG0437	4 iron, 4 sulfur cluster binding
H5C70_RS14495	COG0243	molybdopterin cofactor binding
H5C70_RS14505	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H5C70_RS14520	COG1522	sequence-specific DNA binding
H5C70_RS14525	COG0492	ferredoxin-NADP+ reductase activity
H5C70_RS14530	COG4988	ABC transporter
H5C70_RS14535	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
H5C70_RS14555	COG0542	response to heat
H5C70_RS14565	COG1278	Cold shock
H5C70_RS14570	COG0577	efflux transmembrane transporter activity
H5C70_RS14570	COG1136	(ABC) transporter
H5C70_RS14575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H5C70_RS14580	COG2990	Protein conserved in bacteria
H5C70_RS14585	COG3593	DNA synthesis involved in DNA repair
H5C70_RS14595	COG2431	L-lysine efflux transmembrane transporter activity
H5C70_RS14605	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H5C70_RS14610	COG0028	Belongs to the TPP enzyme family
H5C70_RS14615	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
H5C70_RS14620	COG0702	epimerase
H5C70_RS14625	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H5C70_RS14630	COG3023	N-Acetylmuramoyl-L-alanine amidase
H5C70_RS14645	COG1126	abc transporter atp-binding protein
H5C70_RS14650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H5C70_RS14655	COG4215	(ABC) transporter
H5C70_RS14660	COG4160	amino acid transport
H5C70_RS14665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H5C70_RS14680	COG1177	transmembrane transport
H5C70_RS14685	COG1176	ABC-type spermidine putrescine transport system, permease component I
H5C70_RS14690	COG3842	ATPase activity
H5C70_RS14695	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
H5C70_RS14730	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H5C70_RS14745	COG3226	Transcriptional regulator
H5C70_RS14750	COG0738	Major facilitator superfamily
H5C70_RS14755	COG0561	phosphatase activity
H5C70_RS14765	COG2814	Major facilitator Superfamily
H5C70_RS14770	COG0671	phosphoesterase, PA-phosphatase related
H5C70_RS14775	COG1349	DNA-binding transcription factor activity
H5C70_RS14780	COG1686	Belongs to the peptidase S11 family
H5C70_RS14785	COG0625	glutathione transferase activity
H5C70_RS14790	COG2133	pyrroloquinoline quinone binding
H5C70_RS14805	COG2199	diguanylate cyclase activity
H5C70_RS14810	COG2200	EAL domain
H5C70_RS14835	COG1446	asparaginase
H5C70_RS14840	COG0303	'Molybdopterin
H5C70_RS14845	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H5C70_RS14850	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H5C70_RS14855	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H5C70_RS14860	COG1882	Formate acetyltransferase
H5C70_RS14865	COG0561	phosphatase activity
H5C70_RS14875	COG3547	Transposase (IS116 IS110 IS902 family)
H5C70_RS14880	COG0488	(ABC) transporter
H5C70_RS14885	COG1376	ErfK ybiS ycfS ynhG family protein
H5C70_RS14890	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
H5C70_RS14895	COG1321	iron dependent repressor
H5C70_RS14905	COG2194	sulfuric ester hydrolase activity
H5C70_RS14910	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H5C70_RS14920	COG5006	permease, DMT superfamily
H5C70_RS14930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H5C70_RS14935	COG0765	amino acid transport
H5C70_RS14940	COG1126	abc transporter atp-binding protein
H5C70_RS14945	COG0668	transmembrane transport
H5C70_RS14960	COG4774	siderophore transport
H5C70_RS14970	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H5C70_RS14980	COG3547	Transposase (IS116 IS110 IS902 family)
H5C70_RS14985	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
H5C70_RS14990	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H5C70_RS14995	COG1199	ATP-dependent helicase activity
H5C70_RS15000	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
H5C70_RS15005	COG0513	Belongs to the DEAD box helicase family
H5C70_RS15010	COG1309	transcriptional regulator
H5C70_RS15020	COG1131	(ABC) transporter
H5C70_RS15025	COG0842	Transport permease protein
H5C70_RS15030	COG0842	Transport permease protein
H5C70_RS15040	COG3568	Endonuclease Exonuclease Phosphatase
H5C70_RS15045	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H5C70_RS15050	COG0392	lysyltransferase activity
H5C70_RS15055	COG0670	Belongs to the BI1 family
H5C70_RS15065	COG0670	Belongs to the BI1 family
H5C70_RS15070	COG0314	molybdopterin synthase activity
H5C70_RS15075	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
H5C70_RS15085	COG0521	Mo-molybdopterin cofactor biosynthetic process
H5C70_RS15095	COG0391	Required for morphogenesis under gluconeogenic growth conditions
H5C70_RS15105	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
H5C70_RS15110	COG2226	methyltransferase
H5C70_RS15125	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H5C70_RS15130	COG1881	PFAM PEBP family protein
H5C70_RS15135	COG4677	pectinesterase activity
H5C70_RS15140	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H5C70_RS15145	COG0471	metal ion transport
H5C70_RS15150	COG2828	Protein conserved in bacteria
H5C70_RS15155	COG0583	DNA-binding transcription factor activity
H5C70_RS15165	COG0561	phosphatase activity
H5C70_RS15175	COG4149	molybdate abc transporter
H5C70_RS15180	COG0725	ABC transporter, periplasmic molybdate-binding protein
H5C70_RS15190	COG2005	Transcriptional regulator
H5C70_RS15190	COG3585	molybdate ion transport
H5C70_RS15195	COG1119	ATPase activity
H5C70_RS15200	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H5C70_RS15205	COG1085	galactose-1-phosphate uridylyltransferase
H5C70_RS15215	COG2017	converts alpha-aldose to the beta-anomer
H5C70_RS15225	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H5C70_RS15235	COG1230	cation diffusion facilitator family transporter
H5C70_RS15240	COG3201	nicotinamide mononucleotide transporter
H5C70_RS15290	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
H5C70_RS15295	COG2885	chlorophyll binding
H5C70_RS15305	COG3064	Membrane
H5C70_RS15310	COG0848	biopolymer transport protein
H5C70_RS15315	COG0811	peptide transport
H5C70_RS15320	COG0824	Thioesterase
H5C70_RS15325	COG3790	cyd operon protein YbgE
H5C70_RS15330	COG4890	Cyd operon protein YbgT
H5C70_RS15335	COG1294	oxidase, subunit
H5C70_RS15340	COG1271	oxidase subunit
H5C70_RS15345	COG0383	alpha-mannosidase activity
H5C70_RS15350	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H5C70_RS15350	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H5C70_RS15350	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H5C70_RS15355	COG2188	Transcriptional regulator
H5C70_RS15360	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H5C70_RS15370	COG0508	dehydrogenase complex catalyzes the overall conversion of
H5C70_RS15375	COG0567	Dehydrogenase, E1 component
H5C70_RS15380	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H5C70_RS15385	COG1053	succinate dehydrogenase
H5C70_RS15390	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
H5C70_RS15395	COG2009	succinate dehydrogenase
H5C70_RS15405	COG0372	Belongs to the citrate synthase family
H5C70_RS15410	COG3539	Fimbrial protein
H5C70_RS15415	COG3188	usher protein
H5C70_RS15420	COG3121	Chaperone
H5C70_RS15425	COG3539	Fimbrial protein
H5C70_RS15430	COG3180	Ammonia monooxygenase
H5C70_RS15445	COG1984	allophanate hydrolase subunit 2
H5C70_RS15450	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
H5C70_RS15455	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H5C70_RS15465	COG0415	Belongs to the DNA photolyase family
H5C70_RS15470	COG3272	Protein of unknown function (DUF1722)
H5C70_RS15505	COG3209	COG3209 Rhs family protein
H5C70_RS15535	COG2205	protein histidine kinase activity
H5C70_RS15540	COG0745	RESPONSE REGULATOR receiver
H5C70_RS15550	COG1982	Orn Lys Arg decarboxylase major
H5C70_RS15555	COG0531	amino acid
H5C70_RS15560	COG0033	Phosphoglucomutase
H5C70_RS15565	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
H5C70_RS15570	COG0596	Alpha beta hydrolase
H5C70_RS15580	COG0716	FMN binding
H5C70_RS15590	COG0735	belongs to the Fur family
H5C70_RS15610	COG2190	(PTS) system
H5C70_RS15610	COG1263	PTS System
H5C70_RS15610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H5C70_RS15620	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
H5C70_RS15625	COG1846	Transcriptional regulator
H5C70_RS15625	COG1940	carbohydrate kinase activity
H5C70_RS15630	COG0647	UMP catabolic process
H5C70_RS15635	COG0367	asparagine synthase
H5C70_RS15675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H5C70_RS15685	COG1702	phosphate starvation-inducible protein PhoH
H5C70_RS15695	COG4535	Mg2 and Co2 transporter CorC
H5C70_RS15700	COG0815	Transfers the fatty acyl group on membrane lipoproteins
H5C70_RS15710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H5C70_RS15715	COG0765	amino acid transport
H5C70_RS15720	COG0765	amino acid transport
H5C70_RS15725	COG1126	abc transporter atp-binding protein
H5C70_RS15735	COG0443	Heat shock 70 kDa protein
H5C70_RS15740	COG2214	Heat shock protein DnaJ domain protein
H5C70_RS15750	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
H5C70_RS15755	COG2214	Heat shock protein DnaJ domain protein
H5C70_RS15765	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
H5C70_RS15770	COG2888	peptidyl-tyrosine sulfation
H5C70_RS15785	COG1466	dna polymerase III delta subunit
H5C70_RS15795	COG0406	alpha-ribazole phosphatase activity
H5C70_RS15800	COG0799	negative regulation of ribosome biogenesis
H5C70_RS15810	COG0768	penicillin binding
H5C70_RS15815	COG0772	Belongs to the SEDS family
H5C70_RS15820	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H5C70_RS15825	COG1686	Belongs to the peptidase S11 family
H5C70_RS15840	COG0583	DNA-binding transcription factor activity
H5C70_RS15850	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H5C70_RS15855	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H5C70_RS15875	COG3069	C4-dicarboxylate transmembrane transporter activity
H5C70_RS15880	COG4565	transcriptional regulatory protein
H5C70_RS15885	COG3290	protein histidine kinase activity
H5C70_RS15890	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
H5C70_RS15900	COG2301	Belongs to the HpcH HpaI aldolase family
H5C70_RS15905	COG3051	citrate lyase alpha subunit
H5C70_RS15920	COG0471	metal ion transport
H5C70_RS15925	COG3719	Belongs to the RNase T2 family
H5C70_RS15930	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H5C70_RS15935	COG1063	alcohol dehydrogenase
H5C70_RS15940	COG0589	response to stress
H5C70_RS15945	COG3634	alkyl hydroperoxide reductase activity
H5C70_RS15950	COG0450	alkyl hydroperoxide reductase
H5C70_RS15955	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H5C70_RS15960	COG0583	DNA-binding transcription factor activity
H5C70_RS15965	COG3969	phosphoadenosine phosphosulfate
H5C70_RS15970	COG1475	DNA binding
H5C70_RS15975	COG0436	Aminotransferase
H5C70_RS15980	COG0371	Dehydrogenase
H5C70_RS15985	COG2879	small protein
H5C70_RS15990	COG1966	Carbon starvation protein
H5C70_RS15995	COG2050	protein possibly involved in aromatic compounds catabolism
H5C70_RS16000	COG1028	Short-chain dehydrogenase reductase Sdr
H5C70_RS16005	COG3433	isochorismatase activity
H5C70_RS16005	COG1535	isochorismatase
H5C70_RS16010	COG1021	2,3-dihydroxybenzoate-AMP ligase
H5C70_RS16015	COG1169	isochorismate synthase
H5C70_RS16020	COG4592	Periplasmic binding protein
H5C70_RS16030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H5C70_RS16035	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H5C70_RS16040	COG1120	ATPase activity
H5C70_RS16045	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
H5C70_RS16050	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H5C70_RS16050	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
H5C70_RS16055	COG3251	PFAM MbtH domain protein
H5C70_RS16060	COG2382	esterase
H5C70_RS16065	COG4771	TonB-dependent receptor
H5C70_RS16070	COG2977	Belongs to the P-Pant transferase superfamily
H5C70_RS16095	COG2315	Protein conserved in bacteria
H5C70_RS16100	COG0778	Nitroreductase
H5C70_RS16105	COG0668	transmembrane transport
H5C70_RS16110	COG1113	amino acid transport
H5C70_RS16115	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H5C70_RS16120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H5C70_RS16125	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H5C70_RS16130	COG1538	Outer membrane efflux protein
H5C70_RS16135	COG0745	RESPONSE REGULATOR receiver
H5C70_RS16140	COG5002	protein histidine kinase activity
H5C70_RS16160	COG3209	COG3209 Rhs family protein
H5C70_RS16160	COG4104	PAAR repeat-containing protein
H5C70_RS16175	COG5433	transposase activity
H5C70_RS16180	COG1215	transferase activity, transferring glycosyl groups
H5C70_RS16185	COG4783	chaperone-mediated protein folding
H5C70_RS16195	COG2207	Transcriptional regulator
H5C70_RS16200	COG4571	Outer membrane protease
H5C70_RS16215	COG0500	methyltransferase
H5C70_RS16230	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H5C70_RS16235	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
H5C70_RS16240	COG5301	cellulose 1,4-beta-cellobiosidase activity
H5C70_RS16275	COG1196	nuclear chromosome segregation
H5C70_RS16325	COG1030	water channel activity
H5C70_RS16345	COG4220	transposase activity
H5C70_RS16365	COG3772	lysozyme
H5C70_RS16510	COG0582	viral genome integration into host DNA
H5C70_RS16520	COG2197	response regulator
H5C70_RS16525	COG3539	Fimbrial protein
H5C70_RS16530	COG3539	Fimbrial protein
H5C70_RS16535	COG3188	usher protein
H5C70_RS16540	COG3121	Chaperone
H5C70_RS16545	COG3539	Fimbrial protein
H5C70_RS16555	COG2501	S4 domain
H5C70_RS16560	COG1988	membrane-bound metal-dependent
H5C70_RS16570	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H5C70_RS16580	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
H5C70_RS16585	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H5C70_RS16590	COG0549	Belongs to the carbamate kinase family
H5C70_RS16600	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H5C70_RS16605	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H5C70_RS16610	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
H5C70_RS16615	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H5C70_RS16620	COG3257	ureidoglycine aminohydrolase activity
H5C70_RS16625	COG1929	Belongs to the glycerate kinase type-1 family
H5C70_RS16630	COG2233	PERMEase
H5C70_RS16640	COG1953	Uracil, thiamine, allantoin
H5C70_RS16645	COG2084	Dehydrogenase
H5C70_RS16650	COG3622	Belongs to the hyi family
H5C70_RS16655	COG3960	tartronate-semialdehyde synthase activity
H5C70_RS16660	COG1414	Transcriptional regulator
H5C70_RS16670	COG0583	DNA-binding transcription factor activity
H5C70_RS16680	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
H5C70_RS16685	COG4181	ATPase activity
H5C70_RS16690	COG2755	lipolytic protein G-D-S-L family
H5C70_RS16695	COG0300	oxidoreductase activity
H5C70_RS16700	COG3118	belongs to the thioredoxin family
H5C70_RS16705	COG0390	transport system, permease component
H5C70_RS16710	COG4619	ABC transporter
H5C70_RS16715	COG0330	HflC and HflK could
H5C70_RS16720	COG1585	Membrane protein implicated in regulation of membrane protease activity
H5C70_RS16725	COG0789	Transcriptional regulator
H5C70_RS16730	COG0531	amino acid
H5C70_RS16735	COG2066	Belongs to the glutaminase family
H5C70_RS16740	COG2217	Heavy metal translocating P-type atpase
H5C70_RS16745	COG3093	addiction module antidote protein HigA
H5C70_RS16750	COG3735	TraB family
H5C70_RS16755	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H5C70_RS16760	COG0737	Belongs to the 5'-nucleotidase family
H5C70_RS16765	COG2223	nitrite transmembrane transporter activity
H5C70_RS16770	COG4651	solute:proton antiporter activity
H5C70_RS16770	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H5C70_RS16775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H5C70_RS16810	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H5C70_RS16820	COG2832	Protein of unknown function (DUF454)
H5C70_RS16825	COG3923	Primosomal replication protein n
H5C70_RS16835	COG1196	nuclear chromosome segregation
H5C70_RS16835	COG3264	Mechanosensitive ion channel
H5C70_RS16840	COG1309	transcriptional regulator
H5C70_RS16845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H5C70_RS16850	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H5C70_RS16865	COG0110	maltose O-acetyltransferase activity
H5C70_RS16875	COG4943	cyclic-guanylate-specific phosphodiesterase activity
H5C70_RS16880	COG5507	3-demethylubiquinone-9 3-methyltransferase
H5C70_RS16890	COG3695	enzyme binding
H5C70_RS16895	COG3126	Type III secretion system lipoprotein chaperone (YscW)
H5C70_RS16900	COG1946	Acyl-CoA thioesterase
H5C70_RS16905	COG0004	ammonium transporteR
H5C70_RS16910	COG0347	Belongs to the P(II) protein family
H5C70_RS16915	COG1132	(ABC) transporter
H5C70_RS16920	COG1132	(ABC) transporter
H5C70_RS16925	COG1522	sequence-specific DNA binding
H5C70_RS16955	COG0824	Thioesterase
H5C70_RS16960	COG1555	photosystem II stabilization
H5C70_RS16965	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H5C70_RS16970	COG0776	regulation of translation
H5C70_RS16975	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
H5C70_RS16995	COG0271	Belongs to the BolA IbaG family
H5C70_RS17000	COG3056	Lipoprotein
H5C70_RS17005	COG2223	nitrite transmembrane transporter activity
H5C70_RS17010	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H5C70_RS17015	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H5C70_RS17020	COG1845	cytochrome c oxidase, subunit III
H5C70_RS17025	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H5C70_RS17050	COG2814	Major facilitator Superfamily
H5C70_RS17060	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H5C70_RS17065	COG0693	protein deglycase activity
H5C70_RS17080	COG0142	geranyltranstransferase activity
H5C70_RS17090	COG0667	Aldo Keto reductase
H5C70_RS17095	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H5C70_RS17100	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H5C70_RS17115	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H5C70_RS17115	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H5C70_RS17125	COG4238	major outer membrane lipoprotein
H5C70_RS17130	COG3248	Nucleoside-binding outer membrane protein
H5C70_RS17135	COG1403	HNH endonuclease
H5C70_RS17140	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H5C70_RS17145	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H5C70_RS17150	COG1862	Preprotein translocase
H5C70_RS17170	COG0366	Alpha amylase catalytic
H5C70_RS17175	COG1113	amino acid transport
H5C70_RS17180	COG1114	Component of the transport system for branched-chain amino acids
H5C70_RS17185	COG5002	protein histidine kinase activity
H5C70_RS17190	COG0745	RESPONSE REGULATOR receiver
H5C70_RS17195	COG0420	3'-5' exonuclease activity
H5C70_RS17200	COG0419	ATPase involved in DNA repair
H5C70_RS17205	COG2814	Major facilitator Superfamily
H5C70_RS17210	COG1940	carbohydrate kinase activity
H5C70_RS17230	COG4126	flavin adenine dinucleotide binding
H5C70_RS17250	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H5C70_RS17255	COG3706	GGDEF domain
H5C70_RS17265	COG1785	Belongs to the alkaline phosphatase family
H5C70_RS17280	COG1181	Belongs to the D-alanine--D-alanine ligase family
H5C70_RS17300	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
H5C70_RS17305	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H5C70_RS17325	COG3468	outer membrane autotransporter barrel domain protein
H5C70_RS17330	COG0113	porphobilinogen synthase activity
H5C70_RS17335	COG2175	clavaminate synthase activity
H5C70_RS17340	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H5C70_RS17350	COG4521	taurine ABC transporter
H5C70_RS17355	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
H5C70_RS17360	COG1215	transferase activity, transferring glycosyl groups
H5C70_RS17390	COG3122	Protein conserved in bacteria
H5C70_RS17395	COG2814	Major facilitator Superfamily
H5C70_RS17430	COG1414	Transcriptional regulator
H5C70_RS17435	COG1609	Transcriptional regulator
H5C70_RS17440	COG3250	beta-galactosidase activity
H5C70_RS17445	COG2223	nitrite transmembrane transporter activity
H5C70_RS17450	COG0110	maltose O-acetyltransferase activity
H5C70_RS17455	COG2807	transmembrane transport
H5C70_RS17465	COG0288	reversible hydration of carbon dioxide
H5C70_RS17470	COG0583	DNA-binding transcription factor activity
H5C70_RS17475	COG0402	S-adenosylhomocysteine deaminase activity
H5C70_RS17480	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H5C70_RS17485	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H5C70_RS17490	COG2079	MmgE PrpD family protein
H5C70_RS17495	COG0372	Belongs to the citrate synthase family
H5C70_RS17500	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
H5C70_RS17505	COG3829	transcription factor binding
H5C70_RS17515	COG1280	lysine exporter protein (LysE YggA)
H5C70_RS17530	COG1064	alcohol dehydrogenase
H5C70_RS17540	COG1172	Belongs to the binding-protein-dependent transport system permease family
H5C70_RS17545	COG1129	ABC transporter
H5C70_RS17550	COG1879	ABC-type sugar transport system periplasmic component
H5C70_RS17560	COG0402	S-adenosylhomocysteine deaminase activity
H5C70_RS17565	COG0549	Belongs to the carbamate kinase family
H5C70_RS17570	COG1304	FMN binding
H5C70_RS17575	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H5C70_RS17585	COG0666	response to abiotic stimulus
H5C70_RS17595	COG0583	DNA-binding transcription factor activity
H5C70_RS17600	COG2771	luxR family
H5C70_RS17600	COG2200	EAL domain
H5C70_RS17610	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H5C70_RS17635	COG0582	viral genome integration into host DNA
H5C70_RS17640	COG2771	luxR family
H5C70_RS17640	COG2200	EAL domain
H5C70_RS17655	COG3468	outer membrane autotransporter barrel domain protein
H5C70_RS17665	COG1556	Lactate utilization protein
H5C70_RS17670	COG1139	Iron-sulfur cluster binding protein
H5C70_RS17675	COG0247	lactate metabolic process
H5C70_RS17680	COG2207	Transcriptional regulator
H5C70_RS17685	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H5C70_RS17695	COG3059	membrane
H5C70_RS17700	COG0656	L-ascorbic acid biosynthetic process
H5C70_RS17705	COG2207	Transcriptional regulator
H5C70_RS17705	COG3708	Transcriptional regulator
H5C70_RS17710	COG1388	LysM domain
H5C70_RS17750	COG3188	usher protein
H5C70_RS17760	COG3121	Chaperone
H5C70_RS17765	COG0727	PFAM Uncharacterised protein family (UPF0153)
H5C70_RS17770	COG3477	response to acidic pH
H5C70_RS17775	COG2080	2 iron, 2 sulfur cluster binding
H5C70_RS17780	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
H5C70_RS17785	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H5C70_RS17790	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
H5C70_RS17795	COG0583	DNA-binding transcription factor activity
H5C70_RS17815	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
H5C70_RS17835	COG2195	Cleaves the N-terminal amino acid of tripeptides
H5C70_RS17840	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
H5C70_RS17845	COG1690	Belongs to the RtcB family
H5C70_RS17850	COG0454	-acetyltransferase
H5C70_RS17880	COG0791	NLP P60 protein
H5C70_RS17885	COG3077	Addiction module antitoxin, RelB DinJ family
H5C70_RS17890	COG3041	Addiction module toxin RelE StbE family
H5C70_RS17895	COG3034	peptidoglycan biosynthetic process
H5C70_RS17900	COG0121	glutamine amidotransferase
H5C70_RS17910	COG1960	acyl-CoA dehydrogenase activity
H5C70_RS17920	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H5C70_RS17970	COG3209	COG3209 Rhs family protein
H5C70_RS18060	COG3157	Type VI secretion system effector, Hcp
H5C70_RS18065	COG4104	PAAR repeat-containing protein
H5C70_RS18085	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H5C70_RS18095	COG2226	methyltransferase
H5C70_RS18105	COG0741	lytic transglycosylase activity
H5C70_RS18105	COG1388	LysM domain
H5C70_RS18110	COG2226	methyltransferase
H5C70_RS18120	COG0583	DNA-binding transcription factor activity
H5C70_RS18125	COG0656	L-ascorbic acid biosynthetic process
H5C70_RS18160	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
H5C70_RS18165	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H5C70_RS18170	COG2011	ABC-type metal ion transport system permease component
H5C70_RS18175	COG1464	Belongs to the NlpA lipoprotein family
H5C70_RS18185	COG1720	tRNA m6t6A37 methyltransferase activity
H5C70_RS18200	COG3547	Transposase (IS116 IS110 IS902 family)
H5C70_RS18205	COG3015	lipoprotein NlpE involved in copper resistance
H5C70_RS18210	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
H5C70_RS18215	COG4681	YaeQ
H5C70_RS18225	COG4568	rho-dependent transcription termination
H5C70_RS18235	COG0346	lactoylglutathione lyase activity
H5C70_RS18240	COG1982	Orn Lys Arg decarboxylase major
H5C70_RS18250	COG0587	DNA-directed DNA polymerase activity
H5C70_RS18275	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H5C70_RS18280	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
H5C70_RS18290	COG0750	zinc metalloprotease
H5C70_RS18295	COG0575	Belongs to the CDS family
H5C70_RS18300	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H5C70_RS18305	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
H5C70_RS18330	COG0024	Methionine aminopeptidase
H5C70_RS18350	COG3835	regulator
H5C70_RS18355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H5C70_RS18370	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H5C70_RS18375	COG2860	membrane
H5C70_RS18400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H5C70_RS18405	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H5C70_RS18410	COG1120	ATPase activity
H5C70_RS18415	COG4774	siderophore transport
H5C70_RS18420	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H5C70_RS18425	COG1643	Atp-dependent helicase
H5C70_RS18430	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
H5C70_RS18440	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H5C70_RS18450	COG0617	tRNA 3'-terminal CCA addition
H5C70_RS18455	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H5C70_RS18460	COG3539	Fimbrial protein
H5C70_RS18465	COG3121	Chaperone
H5C70_RS18470	COG3188	usher protein
H5C70_RS18475	COG3539	Fimbrial protein
H5C70_RS18480	COG3539	Fimbrial protein
H5C70_RS18485	COG3539	Fimbrial protein
H5C70_RS18490	COG3539	Fimbrial protein
H5C70_RS18505	COG5464	transposase or invertase
H5C70_RS18515	COG0726	polysaccharide deacetylase
H5C70_RS18520	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
H5C70_RS18525	COG0842	Transport permease protein
H5C70_RS18530	COG1131	(ABC) transporter
H5C70_RS18535	COG0288	reversible hydration of carbon dioxide
H5C70_RS18540	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
H5C70_RS18545	COG4993	Dehydrogenase
H5C70_RS18550	COG3547	Transposase (IS116 IS110 IS902 family)
H5C70_RS18555	COG2132	Multicopper oxidase
H5C70_RS18580	COG1049	propionate catabolic process, 2-methylcitrate cycle
H5C70_RS18585	COG3064	Membrane
H5C70_RS18590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H5C70_RS18595	COG0508	dehydrogenase complex catalyzes the overall conversion of
H5C70_RS18600	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
H5C70_RS18605	COG2186	Transcriptional regulator
H5C70_RS18610	COG1113	amino acid transport
H5C70_RS18615	COG3725	Membrane protein required for beta-lactamase induction
H5C70_RS18620	COG3023	N-Acetylmuramoyl-L-alanine amidase
H5C70_RS18625	COG0157	Belongs to the NadC ModD family
H5C70_RS18630	COG4969	Belongs to the N-Me-Phe pilin family
H5C70_RS18635	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H5C70_RS18640	COG1459	type II secretion system
H5C70_RS18655	COG0237	dephospho-CoA kinase activity
H5C70_RS18670	COG0494	nUDIX hydrolase
H5C70_RS18690	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H5C70_RS18695	COG0849	cell division
H5C70_RS18700	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H5C70_RS18705	COG1181	Belongs to the D-alanine--D-alanine ligase family
H5C70_RS18720	COG0772	Belongs to the SEDS family
H5C70_RS18735	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H5C70_RS18740	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H5C70_RS18745	COG0768	penicillin binding
H5C70_RS18750	COG3116	cell division
H5C70_RS18765	COG1609	Transcriptional regulator
H5C70_RS18775	COG0440	acetolactate synthase activity
H5C70_RS18780	COG0028	Belongs to the TPP enzyme family
H5C70_RS18790	COG0583	DNA-binding transcription factor activity
H5C70_RS18805	COG0473	3-isopropylmalate dehydrogenase activity
H5C70_RS18820	COG2814	Major facilitator Superfamily
H5C70_RS18835	COG4143	(ABC) transporter
H5C70_RS18840	COG1178	ABC-type Fe3 transport system permease component
H5C70_RS18850	COG0586	Pfam SNARE associated Golgi protein
H5C70_RS18855	COG4977	sequence-specific DNA binding
H5C70_RS18870	COG0235	Class ii aldolase
H5C70_RS18875	COG0417	DNA replication proofreading
H5C70_RS18885	COG0564	pseudouridine synthase activity
H5C70_RS18890	COG3547	Transposase (IS116 IS110 IS902 family)
H5C70_RS18895	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
H5C70_RS18900	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
H5C70_RS18905	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H5C70_RS18930	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H5C70_RS18945	COG2271	Major facilitator Superfamily
H5C70_RS18950	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
H5C70_RS18955	COG0644	oxidoreductase
H5C70_RS19005	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
H5C70_RS19010	COG0505	Belongs to the CarA family
H5C70_RS19030	COG1047	Peptidyl-prolyl cis-trans
H5C70_RS19045	COG0196	riboflavin kinase activity
H5C70_RS19075	COG0583	DNA-binding transcription factor activity
H5C70_RS19105	COG4735	regulation of single-species biofilm formation
H5C70_RS19110	COG1584	GPR1 FUN34 yaaH family protein
H5C70_RS19115	COG0521	Mo-molybdopterin cofactor biosynthetic process
H5C70_RS19120	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H5C70_RS19125	COG1115	amino acid carrier protein
H5C70_RS19135	COG3547	Transposase (IS116 IS110 IS902 family)
H5C70_RS19145	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H5C70_RS19155	COG0460	homoserine dehydrogenase
H5C70_RS19155	COG0527	aspartate kinase activity
H5C70_RS19165	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
H5C70_RS19175	COG0745	RESPONSE REGULATOR receiver
H5C70_RS19180	COG4452	Inner membrane protein CreD
H5C70_RS19185	COG2205	protein histidine kinase activity
H5C70_RS19190	COG0745	RESPONSE REGULATOR receiver
H5C70_RS19195	COG3045	CreA protein
H5C70_RS19200	COG3708	Transcriptional regulator
H5C70_RS19200	COG2207	Transcriptional regulator
H5C70_RS19220	COG0741	lytic transglycosylase activity
H5C70_RS19225	COG0488	(ABC) transporter
H5C70_RS19230	COG1056	cytidyltransferase-related domain
H5C70_RS19230	COG3172	ATPase kinase involved in NAD metabolism
H5C70_RS19235	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
H5C70_RS19240	COG0560	Phosphoserine phosphatase
H5C70_RS19245	COG3726	membrane protein affecting hemolysin expression
H5C70_RS19280	COG1328	CTP reductase activity
H5C70_RS19285	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H5C70_RS19290	COG0084	hydrolase, TatD family'
H5C70_RS19295	COG4667	esterase of the alpha-beta hydrolase superfamily
H5C70_RS19305	COG2823	Periplasmic or secreted lipoprotein
H5C70_RS19315	COG1011	Hydrolase
H5C70_RS19320	COG0456	acetyltransferase
H5C70_RS19325	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
H5C70_RS19355	COG4114	ferric iron reductase
H5C70_RS19360	COG2197	response regulator
H5C70_RS19365	COG2197	response regulator
H5C70_RS19370	COG2966	Psort location CytoplasmicMembrane, score
H5C70_RS19385	COG1484	DNA-dependent DNA replication
H5C70_RS19400	COG1063	alcohol dehydrogenase
H5C70_RS19405	COG1802	Transcriptional regulator
H5C70_RS19410	COG2271	Major facilitator Superfamily
H5C70_RS19415	COG0840	transmembrane signaling receptor activity
H5C70_RS19420	COG1966	Carbon starvation protein
H5C70_RS19425	COG2879	small protein
H5C70_RS19430	COG0523	cobalamin synthesis protein
H5C70_RS19445	COG1715	Restriction endonuclease
H5C70_RS19450	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
H5C70_RS19455	COG0732	type I restriction modification DNA specificity domain
H5C70_RS19460	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
H5C70_RS19470	COG5457	Domain of unknown function (DUF1127)
H5C70_RS19475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H5C70_RS19490	COG2814	Major facilitator Superfamily
H5C70_RS19495	COG2733	membrane
H5C70_RS19500	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
H5C70_RS19505	COG1924	4 iron, 4 sulfur cluster binding
H5C70_RS19520	COG0477	Major facilitator Superfamily
H5C70_RS19530	COG3366	ferrous iron transmembrane transporter activity
H5C70_RS19535	COG0700	Nucleoside recognition
H5C70_RS19540	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
H5C70_RS19545	COG0583	DNA-binding transcription factor activity
H5C70_RS19565	COG2186	Transcriptional regulator
H5C70_RS19570	COG0246	Mannitol dehydrogenase
H5C70_RS19580	COG2610	gluconate transmembrane transporter activity
H5C70_RS19585	COG3539	Fimbrial protein
H5C70_RS19590	COG3539	Fimbrial protein
H5C70_RS19595	COG3539	Fimbrial protein
H5C70_RS19600	COG3188	usher protein
H5C70_RS19605	COG3121	Chaperone
H5C70_RS19610	COG3539	Fimbrial protein
H5C70_RS19620	COG4974	Belongs to the 'phage' integrase family
H5C70_RS19645	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
H5C70_RS19650	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
H5C70_RS19660	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
H5C70_RS19660	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H5C70_RS19675	COG3153	acetyltransferase
H5C70_RS19680	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
H5C70_RS19690	COG1363	Peptidase, m42
H5C70_RS19695	COG3414	Phosphotransferase system galactitol-specific IIB component
H5C70_RS19700	COG3775	system Galactitol-specific IIC component
H5C70_RS19705	COG0434	BtpA family
H5C70_RS19710	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H5C70_RS19715	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H5C70_RS19720	COG1349	DNA-binding transcription factor activity
H5C70_RS19725	COG1414	Transcriptional regulator
H5C70_RS19730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H5C70_RS19735	COG0129	dihydroxy-acid dehydratase activity
H5C70_RS19740	COG2610	gluconate transmembrane transporter activity
H5C70_RS19745	COG2390	Transcriptional regulator
H5C70_RS19770	COG1215	transferase activity, transferring glycosyl groups
H5C70_RS19775	COG1401	restriction endodeoxyribonuclease activity
H5C70_RS19835	COG2003	Belongs to the UPF0758 family
H5C70_RS19850	COG4372	Transposase
H5C70_RS19855	COG3436	PFAM IS66 Orf2 family protein
H5C70_RS19870	COG3468	outer membrane autotransporter barrel domain protein
H5C70_RS19920	COG3436	PFAM IS66 Orf2 family protein
H5C70_RS19925	COG4372	Transposase
H5C70_RS19945	COG1595	DNA-templated transcription, initiation
H5C70_RS19950	COG3712	iron ion homeostasis
H5C70_RS19955	COG4772	TonB-dependent receptor
H5C70_RS19960	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
H5C70_RS19965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H5C70_RS19970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H5C70_RS19975	COG1120	ATPase activity
H5C70_RS19980	COG2085	NADP oxidoreductase coenzyme F420-dependent
H5C70_RS19995	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H5C70_RS20020	COG0604	alcohol dehydrogenase
H5C70_RS20030	COG1349	DNA-binding transcription factor activity
H5C70_RS20040	COG0738	Major facilitator superfamily
H5C70_RS20070	COG2271	Major facilitator Superfamily
H5C70_RS20075	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
H5C70_RS20080	COG2721	sulfolactate sulfo-lyase activity
H5C70_RS20085	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H5C70_RS20090	COG1414	Transcriptional regulator
H5C70_RS20125	COG1064	alcohol dehydrogenase
H5C70_RS20130	COG0433	COG0433 Predicted ATPase
H5C70_RS20135	COG0795	lipopolysaccharide-transporting ATPase activity
H5C70_RS20140	COG0795	lipopolysaccharide-transporting ATPase activity
H5C70_RS20150	COG2927	DNA polymerase III (CHI subunit)
H5C70_RS20160	COG4269	membrane
H5C70_RS20165	COG0456	acetyltransferase
H5C70_RS20170	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
H5C70_RS20185	COG2731	YhcH YjgK YiaL family protein
H5C70_RS20190	COG1309	transcriptional regulator
H5C70_RS20195	COG1028	Short-chain dehydrogenase reductase Sdr
H5C70_RS20200	COG0251	oxidation-reduction process
H5C70_RS20220	COG0251	oxidation-reduction process
H5C70_RS20225	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H5C70_RS20235	COG1609	Transcriptional regulator
H5C70_RS20240	COG1263	PTS System
H5C70_RS20240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H5C70_RS20245	COG0366	Alpha amylase catalytic
H5C70_RS20250	COG1328	CTP reductase activity
H5C70_RS20255	COG0602	queuosine metabolic process
H5C70_RS20260	COG3783	Cytochrome b(562)
H5C70_RS20265	COG0312	modulator of DNA gyrase
H5C70_RS20275	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H5C70_RS20285	COG1172	Belongs to the binding-protein-dependent transport system permease family
H5C70_RS20290	COG1172	Belongs to the binding-protein-dependent transport system permease family
H5C70_RS20295	COG1129	ABC transporter
H5C70_RS20300	COG1879	ABC-type sugar transport system periplasmic component
H5C70_RS20305	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
H5C70_RS20310	COG2337	Toxic component of a toxin-antitoxin (TA) module
H5C70_RS20315	COG2336	PFAM SpoVT AbrB
H5C70_RS20320	COG2105	PFAM AIG2 family protein
H5C70_RS20325	COG2911	Protein conserved in bacteria
H5C70_RS20330	COG0729	surface antigen
H5C70_RS20340	COG1253	flavin adenine dinucleotide binding
H5C70_RS20350	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
H5C70_RS20355	COG1218	3'(2'),5'-bisphosphate nucleotidase
H5C70_RS20360	COG0737	Belongs to the 5'-nucleotidase family
H5C70_RS20365	COG1733	regulation of RNA biosynthetic process
H5C70_RS20370	COG0702	epimerase
H5C70_RS20375	COG0697	spore germination
H5C70_RS20385	COG1113	amino acid transport
H5C70_RS20390	COG0545	Peptidyl-prolyl cis-trans isomerase
H5C70_RS20395	COG3061	Opacity-associated protein A
H5C70_RS20400	COG1309	transcriptional regulator
H5C70_RS20415	COG1024	Enoyl-CoA hydratase
H5C70_RS20420	COG4670	ketone body catabolic process
H5C70_RS20425	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
H5C70_RS20430	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
H5C70_RS20440	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H5C70_RS20450	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
H5C70_RS20485	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H5C70_RS20490	COG3414	Phosphotransferase system galactitol-specific IIB component
H5C70_RS20495	COG3037	sugar-specific permease SgaT UlaA
H5C70_RS20510	COG1073	alpha beta
H5C70_RS20515	COG3650	response to hydrogen peroxide
H5C70_RS20525	COG1960	acyl-CoA dehydrogenase activity
H5C70_RS20530	COG0754	glutathionylspermidine amidase activity
H5C70_RS20535	COG5463	Belongs to the UPF0441 family
H5C70_RS20540	COG3766	membrane
H5C70_RS20550	COG1842	Phage shock protein A
H5C70_RS20555	COG3789	protein conserved in bacteria
H5C70_RS20560	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H5C70_RS20565	COG0557	exoribonuclease II activity
H5C70_RS20580	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
H5C70_RS20585	COG0330	HflC and HflK could
H5C70_RS20590	COG0330	HflC and HflK could
H5C70_RS20595	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H5C70_RS20615	COG0860	N-Acetylmuramoyl-L-alanine amidase
H5C70_RS20620	COG0802	atpase or kinase
H5C70_RS20625	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
H5C70_RS20625	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H5C70_RS20630	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H5C70_RS20670	COG3264	Mechanosensitive ion channel
H5C70_RS20670	COG1511	domain protein
H5C70_RS20675	COG0531	amino acid
H5C70_RS20685	COG1053	succinate dehydrogenase
H5C70_RS20690	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H5C70_RS20705	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H5C70_RS20710	COG3040	lipid binding
H5C70_RS20715	COG2076	Multidrug Resistance protein
H5C70_RS20720	COG5510	response to toxic substance
H5C70_RS20725	COG5510	response to toxic substance
H5C70_RS20735	COG1509	lysine 2,3-aminomutase activity
H5C70_RS20760	COG0531	amino acid
H5C70_RS20765	COG3030	protein affecting phage T7 exclusion by the F plasmid
H5C70_RS20770	COG1027	Aspartate ammonia-lyase
H5C70_RS20775	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
H5C70_RS20790	COG1309	transcriptional regulator
H5C70_RS20800	COG0582	viral genome integration into host DNA
H5C70_RS20830	COG0531	amino acid
H5C70_RS20835	COG1982	Orn Lys Arg decarboxylase major
H5C70_RS20840	COG0531	amino acid
H5C70_RS20850	COG0604	alcohol dehydrogenase
H5C70_RS20905	COG2831	hemolysin activation secretion protein
H5C70_RS20930	COG4869	propanediol catabolic process
H5C70_RS20935	COG4820	ethanolamine utilization protein (EutJ)
H5C70_RS20970	COG1012	belongs to the aldehyde dehydrogenase family
H5C70_RS20980	COG0693	protein deglycase activity
H5C70_RS20985	COG1882	Formate acetyltransferase
H5C70_RS20990	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H5C70_RS21005	COG3344	reverse transcriptase
H5C70_RS21010	COG2972	Histidine kinase
H5C70_RS21015	COG2207	Transcriptional regulator
H5C70_RS21020	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
H5C70_RS21080	COG3596	GTP binding
H5C70_RS21085	COG2378	regulation of single-species biofilm formation
H5C70_RS21110	COG2003	Belongs to the UPF0758 family
H5C70_RS21145	COG3710	Transcriptional regulator
H5C70_RS21150	COG0531	amino acid
H5C70_RS21155	COG1982	Orn Lys Arg decarboxylase major
H5C70_RS21160	COG3104	oligopeptide transport
H5C70_RS21165	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
H5C70_RS21180	COG2388	GCN5-related N-acetyl-transferase
H5C70_RS21185	COG3592	Divergent 4Fe-4S mono-cluster
H5C70_RS21190	COG3290	protein histidine kinase activity
H5C70_RS21195	COG4565	transcriptional regulatory protein
H5C70_RS21200	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
H5C70_RS21205	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
H5C70_RS21205	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H5C70_RS21210	COG3647	Membrane
H5C70_RS21215	COG2211	Major facilitator Superfamily
H5C70_RS21220	COG1486	melibiose metabolic process
H5C70_RS21225	COG2169	Transcriptional regulator
H5C70_RS21230	COG1982	Orn Lys Arg decarboxylase major
H5C70_RS21235	COG2207	Transcriptional regulator
H5C70_RS21240	COG0531	amino acid
H5C70_RS21245	COG2194	sulfuric ester hydrolase activity
H5C70_RS21250	COG0745	RESPONSE REGULATOR receiver
H5C70_RS21255	COG0642	Histidine kinase
H5C70_RS21265	COG0477	Major facilitator Superfamily
H5C70_RS21280	COG2824	Alkylphosphonate utilization operon protein PhnA
H5C70_RS21285	COG2764	glyoxalase bleomycin resistance protein dioxygenase
H5C70_RS21295	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
H5C70_RS21300	COG3639	organic phosphonate transmembrane transporter activity
H5C70_RS21305	COG2188	Transcriptional regulator
H5C70_RS21310	COG3624	Phosphonate C-P lyase system protein PhnG
H5C70_RS21315	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
H5C70_RS21320	COG3626	phosphonate metabolism
H5C70_RS21325	COG3627	carbon phosphorus lyase activity
H5C70_RS21330	COG4107	phosphonate C-P lyase system protein PhnK
H5C70_RS21335	COG4778	phosphonate C-P lyase system protein PhnL
H5C70_RS21340	COG3454	Phosphonate metabolism
H5C70_RS21345	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
H5C70_RS21350	COG0456	acetyltransferase
H5C70_RS21355	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
H5C70_RS21365	COG0698	ribose 5-phosphate isomerase
H5C70_RS21370	COG2015	COG2015, Alkyl sulfatase and related hydrolases
H5C70_RS21380	COG1566	PFAM secretion protein HlyD family protein
H5C70_RS21385	COG1289	transmembrane transporter activity
H5C70_RS21400	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
H5C70_RS21405	COG1301	dicarboxylic acid transport
H5C70_RS21410	COG4235	cytochrome complex assembly
H5C70_RS21415	COG3088	subunit of a heme lyase
H5C70_RS21420	COG1138	Cytochrome C-type biogenesis protein
H5C70_RS21425	COG3301	Polysulphide reductase, NrfD
H5C70_RS21430	COG0437	4 iron, 4 sulfur cluster binding
H5C70_RS21435	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
H5C70_RS21445	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H5C70_RS21450	COG3162	membrane
H5C70_RS21460	COG1357	PFAM Pentapeptide repeats (8 copies)
H5C70_RS21465	COG0025	NhaP-type Na H and K H
H5C70_RS21470	COG2252	PERMEase
H5C70_RS21475	COG0789	Transcriptional regulator
H5C70_RS21480	COG2207	Transcriptional regulator
H5C70_RS21485	COG4943	cyclic-guanylate-specific phosphodiesterase activity
H5C70_RS21495	COG0629	single-stranded DNA binding
H5C70_RS21500	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H5C70_RS21505	COG2315	Protein conserved in bacteria
H5C70_RS21510	COG0432	Pfam Uncharacterised protein family UPF0047
H5C70_RS21515	COG3700	Belongs to the class B bacterial acid phosphatase family
H5C70_RS21525	COG1448	Aminotransferase
H5C70_RS21530	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H5C70_RS21535	COG0305	Participates in initiation and elongation during chromosome replication
H5C70_RS21540	COG0604	alcohol dehydrogenase
H5C70_RS21550	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H5C70_RS21560	COG0735	belongs to the Fur family
H5C70_RS21565	COG3237	CsbD-like
H5C70_RS21570	COG0534	Mate efflux family protein
H5C70_RS21580	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
H5C70_RS21615	COG3842	ATPase activity
H5C70_RS21620	COG2182	Extracellular solute-binding protein
H5C70_RS21625	COG1175	transmembrane transport
H5C70_RS21630	COG3833	ABC-type maltose transport systems, permease component
H5C70_RS21635	COG0477	Major facilitator Superfamily
H5C70_RS21635	COG2814	Major facilitator Superfamily
H5C70_RS21650	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H5C70_RS21675	COG0527	aspartate kinase activity
H5C70_RS21680	COG0542	response to heat
H5C70_RS21685	COG3541	Predicted nucleotidyltransferase
H5C70_RS21700	COG1187	pseudouridine synthase activity
H5C70_RS21710	COG1283	sodium-dependent phosphate transmembrane transporter activity
H5C70_RS21715	COG0646	methionine synthase
H5C70_RS21715	COG1410	methionine synthase
H5C70_RS21720	COG1414	Transcriptional regulator
H5C70_RS21735	COG2224	Isocitrate lyase
H5C70_RS21740	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H5C70_RS21750	COG0456	acetyltransferase
H5C70_RS21780	COG0151	Belongs to the GarS family
H5C70_RS21785	COG2204	response regulator
H5C70_RS21790	COG4191	Histidine kinase
H5C70_RS21795	COG3678	ATP-independent chaperone mediated protein folding
H5C70_RS21810	COG3068	Protein conserved in bacteria
H5C70_RS21845	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H5C70_RS21850	COG2104	thiamine diphosphate biosynthetic process
H5C70_RS21860	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
H5C70_RS21900	COG0250	Participates in transcription elongation, termination and antitermination
H5C70_RS21905	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H5C70_RS21940	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
H5C70_RS21940	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
H5C70_RS21990	COG1309	transcriptional regulator
H5C70_RS22000	COG0583	DNA-binding transcription factor activity
H5C70_RS22005	COG2271	Major facilitator Superfamily
H5C70_RS22010	COG4948	Mandelate Racemase Muconate Lactonizing
H5C70_RS22025	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
H5C70_RS22040	COG2194	sulfuric ester hydrolase activity
H5C70_RS22045	COG2207	Transcriptional regulator
H5C70_RS22050	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H5C70_RS22055	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H5C70_RS22060	COG1882	Formate acetyltransferase
H5C70_RS22065	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H5C70_RS22070	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H5C70_RS22075	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H5C70_RS22075	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H5C70_RS22075	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H5C70_RS22080	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H5C70_RS22085	COG0371	Dehydrogenase
H5C70_RS22090	COG3738	Protein conserved in bacteria
H5C70_RS22095	COG0697	spore germination
H5C70_RS22105	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H5C70_RS22110	COG0460	homoserine dehydrogenase
H5C70_RS22110	COG0527	aspartate kinase activity
H5C70_RS22115	COG0626	cystathionine gamma-synthase activity
H5C70_RS22125	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
H5C70_RS22140	COG3209	COG3209 Rhs family protein
H5C70_RS22150	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H5C70_RS22155	COG1609	Transcriptional regulator
H5C70_RS22160	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H5C70_RS22175	COG1575	Belongs to the MenA family. Type 1 subfamily
H5C70_RS22190	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H5C70_RS22200	COG1494	fructose-1,6-bisphosphatase
H5C70_RS22210	COG0589	response to stress
H5C70_RS22215	COG3691	Protein conserved in bacteria
H5C70_RS22220	COG3152	Membrane
H5C70_RS22240	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H5C70_RS22255	COG3678	ATP-independent chaperone mediated protein folding
H5C70_RS22260	COG0745	RESPONSE REGULATOR receiver
H5C70_RS22265	COG2205	protein histidine kinase activity
H5C70_RS22270	COG2258	MOSC domain
H5C70_RS22280	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H5C70_RS22320	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H5C70_RS22325	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H5C70_RS22325	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H5C70_RS22330	COG1363	Peptidase, m42
H5C70_RS22335	COG3711	transcriptional antiterminator
H5C70_RS22335	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H5C70_RS22355	COG0437	4 iron, 4 sulfur cluster binding
H5C70_RS22360	COG2864	formate dehydrogenase
H5C70_RS22370	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H5C70_RS22375	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H5C70_RS22385	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
H5C70_RS22395	COG0456	acetyltransferase
H5C70_RS22410	COG1011	Hydrolase
H5C70_RS22415	COG1349	DNA-binding transcription factor activity
H5C70_RS22420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H5C70_RS22425	COG2084	Dehydrogenase
H5C70_RS22430	COG3684	Belongs to the aldolase LacD family
H5C70_RS22435	COG2942	2-epimerase
H5C70_RS22440	COG2017	converts alpha-aldose to the beta-anomer
H5C70_RS22445	COG1501	Belongs to the glycosyl hydrolase 31 family
H5C70_RS22450	COG2211	Major facilitator Superfamily
H5C70_RS22455	COG2211	Major facilitator Superfamily
H5C70_RS22460	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
H5C70_RS22465	COG2271	Major facilitator Superfamily
H5C70_RS22470	COG1082	Xylose isomerase domain protein TIM barrel
H5C70_RS22475	COG2188	Transcriptional regulator
H5C70_RS22480	COG1217	gtp-binding protein TYPA
H5C70_RS22485	COG0174	glutamine synthetase
H5C70_RS22490	COG3852	Histidine kinase
H5C70_RS22495	COG2204	response regulator
H5C70_RS22505	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H5C70_RS22520	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H5C70_RS22520	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H5C70_RS22525	COG0204	Acyl-transferase
H5C70_RS22545	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H5C70_RS22550	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H5C70_RS22555	COG3084	Protein conserved in bacteria
H5C70_RS22560	COG0746	molybdenum cofactor guanylyltransferase activity
H5C70_RS22565	COG1763	Mo-molybdopterin cofactor biosynthetic process
H5C70_RS22595	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
H5C70_RS22600	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H5C70_RS22605	COG1739	Uncharacterized protein family UPF0029
H5C70_RS22625	COG0543	2 iron, 2 sulfur cluster binding
H5C70_RS22630	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
H5C70_RS22635	COG0250	Participates in transcription elongation, termination and antitermination
H5C70_RS22645	COG0805	protein transport
H5C70_RS22650	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H5C70_RS22655	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H5C70_RS22665	COG3165	ubiquinone biosynthetic process from chorismate
H5C70_RS22675	COG1322	Protein conserved in bacteria
H5C70_RS22680	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
H5C70_RS22685	COG0412	Dienelactone hydrolase
H5C70_RS22695	COG0583	DNA-binding transcription factor activity
H5C70_RS22700	COG0697	spore germination
H5C70_RS22705	COG0561	phosphatase activity
H5C70_RS22710	COG2267	carboxylic ester hydrolase activity
H5C70_RS22715	COG1280	lysine exporter protein (LysE YggA)
H5C70_RS22720	COG1280	lysine exporter protein (LysE YggA)
H5C70_RS22725	COG0514	ATP-dependent DNA helicase (RecQ)
H5C70_RS22730	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
H5C70_RS22735	COG2050	protein possibly involved in aromatic compounds catabolism
H5C70_RS22740	COG2962	Rard protein
H5C70_RS22765	COG0598	Magnesium transport protein CorA
H5C70_RS22770	COG3698	Phosphodiester glycosidase
H5C70_RS22775	COG0210	DNA helicase
H5C70_RS22780	COG1011	Hydrolase
H5C70_RS22790	COG3159	Protein conserved in bacteria
H5C70_RS22800	COG5567	small periplasmic lipoprotein
H5C70_RS22825	COG3072	Adenylate cyclase
H5C70_RS22835	COG1587	Uroporphyrinogen-III synthase
H5C70_RS22840	COG2959	enzyme of heme biosynthesis
H5C70_RS22845	COG3071	HemY protein
H5C70_RS22850	COG3119	arylsulfatase activity
H5C70_RS22855	COG0641	radical SAM
H5C70_RS22880	COG1113	amino acid transport
H5C70_RS22900	COG2244	polysaccharide biosynthetic process
H5C70_RS22905	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H5C70_RS22910	COG0456	acetyltransferase
H5C70_RS22915	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
H5C70_RS22920	COG1088	dTDP-glucose 4,6-dehydratase activity
H5C70_RS22925	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
H5C70_RS22930	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
H5C70_RS22935	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
H5C70_RS22940	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H5C70_RS22945	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
H5C70_RS22955	COG3118	belongs to the thioredoxin family
H5C70_RS22970	COG0210	DNA helicase
H5C70_RS22975	COG3692	DNA binding
H5C70_RS22980	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H5C70_RS22990	COG0583	DNA-binding transcription factor activity
H5C70_RS22995	COG3547	Transposase (IS116 IS110 IS902 family)
H5C70_RS23000	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H5C70_RS23010	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H5C70_RS23015	COG3978	acetolactate synthase activity
H5C70_RS23035	COG0606	chelatase, subunit chli
H5C70_RS23040	COG3085	chromosome segregation
H5C70_RS23075	COG2186	Transcriptional regulator
H5C70_RS23080	COG0477	Major facilitator Superfamily
H5C70_RS23085	COG1609	Transcriptional regulator
H5C70_RS23090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H5C70_RS23095	COG1879	ABC-type sugar transport system periplasmic component
H5C70_RS23100	COG1172	Belongs to the binding-protein-dependent transport system permease family
H5C70_RS23105	COG1129	ABC transporter
H5C70_RS23135	COG1522	sequence-specific DNA binding
H5C70_RS23140	COG0716	FMN binding
H5C70_RS23155	COG3312	ion transport
H5C70_RS23205	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H5C70_RS23220	COG3188	usher protein
H5C70_RS23230	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H5C70_RS23235	COG0573	inorganic phosphate transmembrane transporter activity
H5C70_RS23240	COG0581	inorganic phosphate transmembrane transporter activity
H5C70_RS23245	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H5C70_RS23250	COG0704	Plays a role in the regulation of phosphate uptake
H5C70_RS23255	COG3711	transcriptional antiterminator
H5C70_RS23260	COG2190	(PTS) system
H5C70_RS23260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H5C70_RS23260	COG1263	PTS System
H5C70_RS23265	COG2723	6-phospho-beta-galactosidase activity
H5C70_RS23275	COG2382	esterase
H5C70_RS23280	COG0363	glucosamine-6-phosphate deaminase activity
H5C70_RS23285	COG3196	Protein conserved in bacteria
H5C70_RS23295	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H5C70_RS23300	COG2252	PERMEase
H5C70_RS23305	COG0431	NADPH-dependent FMN reductase
H5C70_RS23310	COG2091	lysine biosynthetic process via aminoadipic acid
H5C70_RS23325	COG0814	amino acid
H5C70_RS23395	COG4571	Outer membrane protease
H5C70_RS23415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H5C70_RS23425	COG1538	Outer membrane efflux protein
H5C70_RS23545	COG0697	spore germination
H5C70_RS23620	COG3436	PFAM IS66 Orf2 family protein
H5C70_RS23635	COG1438	arginine binding
H5C70_RS23640	COG1288	antiporter activity
H5C70_RS23655	COG2235	arginine
H5C70_RS23695	COG4372	Transposase
H5C70_RS23700	COG3436	PFAM IS66 Orf2 family protein
H5C70_RS24105	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
H5C70_RS24120	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H5C70_RS24125	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H5C70_RS24130	COG1121	(ABC) transporter
H5C70_RS24175	COG2948	multi-organism process
H5C70_RS24225	COG0250	Participates in transcription elongation, termination and antitermination
H5C70_RS24280	COG2026	Addiction module toxin, RelE StbE family
H5C70_RS24320	COG1192	Involved in chromosome partitioning
H5C70_RS24365	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H5C70_RS24375	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins