locus-tag	class	description
H0E72_RS00040	COG4695	Portal protein
H0E72_RS00130	COG5301	cellulose 1,4-beta-cellobiosidase activity
H0E72_RS00185	COG3385	transposase activity
H0E72_RS00200	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H0E72_RS00220	COG3152	Membrane
H0E72_RS00225	COG3691	Protein conserved in bacteria
H0E72_RS00230	COG0589	response to stress
H0E72_RS00240	COG1494	fructose-1,6-bisphosphatase
H0E72_RS00250	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H0E72_RS00275	COG1575	Belongs to the MenA family. Type 1 subfamily
H0E72_RS00290	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H0E72_RS00295	COG1609	Transcriptional regulator
H0E72_RS00300	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H0E72_RS00310	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
H0E72_RS00320	COG0626	cystathionine gamma-synthase activity
H0E72_RS00325	COG0527	aspartate kinase activity
H0E72_RS00325	COG0460	homoserine dehydrogenase
H0E72_RS00335	COG0737	Belongs to the 5'-nucleotidase family
H0E72_RS00340	COG0737	Belongs to the 5'-nucleotidase family
H0E72_RS00350	COG0737	Belongs to the 5'-nucleotidase family
H0E72_RS00355	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H0E72_RS00365	COG0697	spore germination
H0E72_RS00370	COG3738	Protein conserved in bacteria
H0E72_RS00375	COG0371	Dehydrogenase
H0E72_RS00380	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H0E72_RS00385	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H0E72_RS00385	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H0E72_RS00385	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H0E72_RS00390	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H0E72_RS00395	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H0E72_RS00400	COG1882	Formate acetyltransferase
H0E72_RS00405	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H0E72_RS00410	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H0E72_RS00415	COG2207	Transcriptional regulator
H0E72_RS00420	COG2194	sulfuric ester hydrolase activity
H0E72_RS00435	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
H0E72_RS00450	COG0583	DNA-binding transcription factor activity
H0E72_RS00460	COG1309	transcriptional regulator
H0E72_RS00475	COG4206	TonB-dependent receptor
H0E72_RS00510	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
H0E72_RS00510	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
H0E72_RS00545	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H0E72_RS00550	COG0250	Participates in transcription elongation, termination and antitermination
H0E72_RS00585	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
H0E72_RS00595	COG2104	thiamine diphosphate biosynthetic process
H0E72_RS00600	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H0E72_RS00635	COG3068	Protein conserved in bacteria
H0E72_RS00650	COG3678	ATP-independent chaperone mediated protein folding
H0E72_RS00655	COG4191	Histidine kinase
H0E72_RS00660	COG2204	response regulator
H0E72_RS00665	COG0151	Belongs to the GarS family
H0E72_RS00715	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H0E72_RS00720	COG2224	Isocitrate lyase
H0E72_RS00730	COG1414	Transcriptional regulator
H0E72_RS00735	COG0646	methionine synthase
H0E72_RS00735	COG1410	methionine synthase
H0E72_RS00740	COG1283	sodium-dependent phosphate transmembrane transporter activity
H0E72_RS00750	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H0E72_RS00790	COG1187	pseudouridine synthase activity
H0E72_RS00800	COG0527	aspartate kinase activity
H0E72_RS00825	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H0E72_RS00840	COG3833	ABC-type maltose transport systems, permease component
H0E72_RS00845	COG1175	transmembrane transport
H0E72_RS00850	COG2182	Extracellular solute-binding protein
H0E72_RS00855	COG3842	ATPase activity
H0E72_RS00870	COG1357	PFAM Pentapeptide repeats (8 copies)
H0E72_RS00890	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
H0E72_RS00900	COG0534	Mate efflux family protein
H0E72_RS00905	COG3237	CsbD-like
H0E72_RS00910	COG0735	belongs to the Fur family
H0E72_RS00920	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H0E72_RS00930	COG0604	alcohol dehydrogenase
H0E72_RS00935	COG0305	Participates in initiation and elongation during chromosome replication
H0E72_RS00940	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H0E72_RS00945	COG1448	Aminotransferase
H0E72_RS00955	COG3700	Belongs to the class B bacterial acid phosphatase family
H0E72_RS00960	COG0432	Pfam Uncharacterised protein family UPF0047
H0E72_RS00965	COG2315	Protein conserved in bacteria
H0E72_RS00970	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H0E72_RS00975	COG0629	single-stranded DNA binding
H0E72_RS00985	COG4943	cyclic-guanylate-specific phosphodiesterase activity
H0E72_RS00990	COG2207	Transcriptional regulator
H0E72_RS00995	COG0789	Transcriptional regulator
H0E72_RS01000	COG2252	PERMEase
H0E72_RS01005	COG0025	NhaP-type Na H and K H
H0E72_RS01015	COG3162	membrane
H0E72_RS01020	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H0E72_RS01030	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
H0E72_RS01035	COG0437	4 iron, 4 sulfur cluster binding
H0E72_RS01040	COG3301	Polysulphide reductase, NrfD
H0E72_RS01045	COG1138	Cytochrome C-type biogenesis protein
H0E72_RS01050	COG3088	subunit of a heme lyase
H0E72_RS01055	COG4235	cytochrome complex assembly
H0E72_RS01060	COG1301	dicarboxylic acid transport
H0E72_RS01065	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
H0E72_RS01080	COG1289	transmembrane transporter activity
H0E72_RS01085	COG1566	PFAM secretion protein HlyD family protein
H0E72_RS01095	COG2015	COG2015, Alkyl sulfatase and related hydrolases
H0E72_RS01100	COG1940	carbohydrate kinase activity
H0E72_RS01105	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H0E72_RS01110	COG1172	Belongs to the binding-protein-dependent transport system permease family
H0E72_RS01115	COG1129	ABC transporter
H0E72_RS01120	COG1879	ABC-type sugar transport system periplasmic component
H0E72_RS01125	COG1737	Transcriptional regulator
H0E72_RS01130	COG0698	ribose 5-phosphate isomerase
H0E72_RS01140	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
H0E72_RS01145	COG0456	acetyltransferase
H0E72_RS01155	COG3454	Phosphonate metabolism
H0E72_RS01160	COG4778	phosphonate C-P lyase system protein PhnL
H0E72_RS01165	COG4107	phosphonate C-P lyase system protein PhnK
H0E72_RS01170	COG3627	carbon phosphorus lyase activity
H0E72_RS01175	COG3626	phosphonate metabolism
H0E72_RS01180	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
H0E72_RS01185	COG3624	Phosphonate C-P lyase system protein PhnG
H0E72_RS01190	COG2188	Transcriptional regulator
H0E72_RS01195	COG3639	organic phosphonate transmembrane transporter activity
H0E72_RS01200	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
H0E72_RS01210	COG2764	glyoxalase bleomycin resistance protein dioxygenase
H0E72_RS01215	COG2824	Alkylphosphonate utilization operon protein PhnA
H0E72_RS01230	COG0477	Major facilitator Superfamily
H0E72_RS01240	COG0642	Histidine kinase
H0E72_RS01245	COG0745	RESPONSE REGULATOR receiver
H0E72_RS01250	COG2194	sulfuric ester hydrolase activity
H0E72_RS01255	COG0531	amino acid
H0E72_RS01260	COG2207	Transcriptional regulator
H0E72_RS01265	COG1982	Orn Lys Arg decarboxylase major
H0E72_RS01270	COG2169	Transcriptional regulator
H0E72_RS01275	COG1486	melibiose metabolic process
H0E72_RS01280	COG2211	Major facilitator Superfamily
H0E72_RS01285	COG3647	Membrane
H0E72_RS01290	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H0E72_RS01290	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
H0E72_RS01295	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
H0E72_RS01300	COG4565	transcriptional regulatory protein
H0E72_RS01305	COG3290	protein histidine kinase activity
H0E72_RS01310	COG3592	Divergent 4Fe-4S mono-cluster
H0E72_RS01315	COG2388	GCN5-related N-acetyl-transferase
H0E72_RS01330	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
H0E72_RS01335	COG3104	oligopeptide transport
H0E72_RS01340	COG1982	Orn Lys Arg decarboxylase major
H0E72_RS01345	COG0531	amino acid
H0E72_RS01350	COG3710	Transcriptional regulator
H0E72_RS01360	COG1309	transcriptional regulator
H0E72_RS01375	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
H0E72_RS01380	COG1027	Aspartate ammonia-lyase
H0E72_RS01385	COG3030	protein affecting phage T7 exclusion by the F plasmid
H0E72_RS01390	COG0531	amino acid
H0E72_RS01415	COG1509	lysine 2,3-aminomutase activity
H0E72_RS01425	COG5510	response to toxic substance
H0E72_RS01430	COG5510	response to toxic substance
H0E72_RS01435	COG2076	Multidrug Resistance protein
H0E72_RS01440	COG3040	lipid binding
H0E72_RS01445	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H0E72_RS01460	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H0E72_RS01465	COG1053	succinate dehydrogenase
H0E72_RS01475	COG0531	amino acid
H0E72_RS01490	COG1511	domain protein
H0E72_RS01490	COG3264	Mechanosensitive ion channel
H0E72_RS01530	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H0E72_RS01535	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H0E72_RS01535	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
H0E72_RS01540	COG0802	atpase or kinase
H0E72_RS01545	COG0860	N-Acetylmuramoyl-L-alanine amidase
H0E72_RS01565	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H0E72_RS01570	COG0330	HflC and HflK could
H0E72_RS01575	COG0330	HflC and HflK could
H0E72_RS01580	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
H0E72_RS01595	COG0557	exoribonuclease II activity
H0E72_RS01600	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H0E72_RS01605	COG3789	protein conserved in bacteria
H0E72_RS01610	COG1842	Phage shock protein A
H0E72_RS01620	COG3766	membrane
H0E72_RS01625	COG5463	Belongs to the UPF0441 family
H0E72_RS01630	COG0754	glutathionylspermidine amidase activity
H0E72_RS01635	COG1960	acyl-CoA dehydrogenase activity
H0E72_RS01645	COG3650	response to hydrogen peroxide
H0E72_RS01650	COG1073	alpha beta
H0E72_RS01665	COG3037	sugar-specific permease SgaT UlaA
H0E72_RS01675	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H0E72_RS01710	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
H0E72_RS01720	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H0E72_RS01730	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
H0E72_RS01735	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
H0E72_RS01740	COG4670	ketone body catabolic process
H0E72_RS01745	COG1024	Enoyl-CoA hydratase
H0E72_RS01760	COG1309	transcriptional regulator
H0E72_RS01765	COG3061	Opacity-associated protein A
H0E72_RS01770	COG0545	Peptidyl-prolyl cis-trans isomerase
H0E72_RS01775	COG1113	amino acid transport
H0E72_RS01795	COG0697	spore germination
H0E72_RS01800	COG0702	epimerase
H0E72_RS01805	COG1733	regulation of RNA biosynthetic process
H0E72_RS01810	COG0737	Belongs to the 5'-nucleotidase family
H0E72_RS01815	COG1218	3'(2'),5'-bisphosphate nucleotidase
H0E72_RS01820	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
H0E72_RS01830	COG1253	flavin adenine dinucleotide binding
H0E72_RS01840	COG0729	surface antigen
H0E72_RS01845	COG2911	Protein conserved in bacteria
H0E72_RS01850	COG2105	PFAM AIG2 family protein
H0E72_RS01855	COG2336	PFAM SpoVT AbrB
H0E72_RS01860	COG2337	Toxic component of a toxin-antitoxin (TA) module
H0E72_RS01865	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
H0E72_RS01870	COG1879	ABC-type sugar transport system periplasmic component
H0E72_RS01875	COG1129	ABC transporter
H0E72_RS01880	COG1172	Belongs to the binding-protein-dependent transport system permease family
H0E72_RS01885	COG1172	Belongs to the binding-protein-dependent transport system permease family
H0E72_RS01895	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H0E72_RS01905	COG0312	modulator of DNA gyrase
H0E72_RS01910	COG3783	Cytochrome b(562)
H0E72_RS01915	COG3077	Addiction module antitoxin, RelB DinJ family
H0E72_RS01920	COG2026	Addiction module toxin, RelE StbE family
H0E72_RS01925	COG0602	queuosine metabolic process
H0E72_RS01930	COG1328	CTP reductase activity
H0E72_RS01935	COG0366	Alpha amylase catalytic
H0E72_RS01940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H0E72_RS01940	COG1263	PTS System
H0E72_RS01945	COG1609	Transcriptional regulator
H0E72_RS01955	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H0E72_RS01960	COG0251	oxidation-reduction process
H0E72_RS01980	COG0251	oxidation-reduction process
H0E72_RS01985	COG1028	Short-chain dehydrogenase reductase Sdr
H0E72_RS01990	COG1309	transcriptional regulator
H0E72_RS01995	COG2731	YhcH YjgK YiaL family protein
H0E72_RS02010	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
H0E72_RS02015	COG0456	acetyltransferase
H0E72_RS02020	COG4269	membrane
H0E72_RS02025	COG0525	valine-tRNA ligase activity
H0E72_RS02030	COG2927	DNA polymerase III (CHI subunit)
H0E72_RS02040	COG0795	lipopolysaccharide-transporting ATPase activity
H0E72_RS02045	COG0795	lipopolysaccharide-transporting ATPase activity
H0E72_RS02050	COG0433	COG0433 Predicted ATPase
H0E72_RS02055	COG1609	Transcriptional regulator
H0E72_RS02060	COG2610	gluconate transmembrane transporter activity
H0E72_RS02065	COG1028	Short-chain dehydrogenase reductase Sdr
H0E72_RS02070	COG1063	alcohol dehydrogenase
H0E72_RS02075	COG3265	gluconokinase activity
H0E72_RS02080	COG1064	alcohol dehydrogenase
H0E72_RS02090	COG0582	viral genome integration into host DNA
H0E72_RS02225	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
H0E72_RS02235	COG1111	helicase
H0E72_RS02235	COG1205	dead DEAH box helicase
H0E72_RS02240	COG0210	DNA helicase
H0E72_RS02265	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
H0E72_RS02270	COG0582	viral genome integration into host DNA
H0E72_RS02275	COG4974	Belongs to the 'phage' integrase family
H0E72_RS02280	COG3539	Fimbrial protein
H0E72_RS02285	COG3539	Fimbrial protein
H0E72_RS02290	COG3121	Chaperone
H0E72_RS02295	COG3188	usher protein
H0E72_RS02300	COG3539	Fimbrial protein
H0E72_RS02305	COG3539	Fimbrial protein
H0E72_RS02310	COG3539	Fimbrial protein
H0E72_RS02320	COG3385	transposase activity
H0E72_RS02335	COG0246	Mannitol dehydrogenase
H0E72_RS02340	COG2186	Transcriptional regulator
H0E72_RS02360	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H0E72_RS02360	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H0E72_RS02365	COG1461	Dihydroxyacetone kinase
H0E72_RS02370	COG2376	Dihydroxyacetone kinase
H0E72_RS02385	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H0E72_RS02395	COG1929	Belongs to the glycerate kinase type-1 family
H0E72_RS02400	COG2084	Dehydrogenase
H0E72_RS02405	COG3622	Belongs to the hyi family
H0E72_RS02410	COG3960	tartronate-semialdehyde synthase activity
H0E72_RS02415	COG3284	Transcriptional regulator
H0E72_RS02425	COG1757	Na H antiporter
H0E72_RS02430	COG0583	DNA-binding transcription factor activity
H0E72_RS02435	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
H0E72_RS02440	COG0700	Nucleoside recognition
H0E72_RS02445	COG3366	ferrous iron transmembrane transporter activity
H0E72_RS02455	COG1470	cell adhesion involved in biofilm formation
H0E72_RS02455	COG1388	LysM domain
H0E72_RS02460	COG0477	Major facilitator Superfamily
H0E72_RS02465	COG3204	pilus organization
H0E72_RS02480	COG1924	4 iron, 4 sulfur cluster binding
H0E72_RS02485	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
H0E72_RS02490	COG2733	membrane
H0E72_RS02495	COG2814	Major facilitator Superfamily
H0E72_RS02510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H0E72_RS02515	COG5457	Domain of unknown function (DUF1127)
H0E72_RS02535	COG0210	DNA helicase
H0E72_RS02540	COG0523	cobalamin synthesis protein
H0E72_RS02545	COG2879	small protein
H0E72_RS02550	COG1966	Carbon starvation protein
H0E72_RS02560	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
H0E72_RS02570	COG4145	pantothenate transmembrane transporter activity
H0E72_RS02580	COG0840	transmembrane signaling receptor activity
H0E72_RS02585	COG2271	Major facilitator Superfamily
H0E72_RS02590	COG1802	Transcriptional regulator
H0E72_RS02595	COG1063	alcohol dehydrogenase
H0E72_RS02610	COG1484	DNA-dependent DNA replication
H0E72_RS02625	COG2966	Psort location CytoplasmicMembrane, score
H0E72_RS02630	COG2197	response regulator
H0E72_RS02635	COG2197	response regulator
H0E72_RS02640	COG4114	ferric iron reductase
H0E72_RS02670	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
H0E72_RS02675	COG0456	acetyltransferase
H0E72_RS02680	COG1011	Hydrolase
H0E72_RS02690	COG2823	Periplasmic or secreted lipoprotein
H0E72_RS02700	COG4667	esterase of the alpha-beta hydrolase superfamily
H0E72_RS02705	COG0084	hydrolase, TatD family'
H0E72_RS02710	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H0E72_RS02715	COG1328	CTP reductase activity
H0E72_RS02750	COG3726	membrane protein affecting hemolysin expression
H0E72_RS02755	COG0560	Phosphoserine phosphatase
H0E72_RS02760	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
H0E72_RS02765	COG3172	ATPase kinase involved in NAD metabolism
H0E72_RS02765	COG1056	cytidyltransferase-related domain
H0E72_RS02775	COG0488	(ABC) transporter
H0E72_RS02780	COG0741	lytic transglycosylase activity
H0E72_RS02800	COG3708	Transcriptional regulator
H0E72_RS02800	COG2207	Transcriptional regulator
H0E72_RS02805	COG3045	CreA protein
H0E72_RS02810	COG0745	RESPONSE REGULATOR receiver
H0E72_RS02815	COG2205	protein histidine kinase activity
H0E72_RS02820	COG4452	Inner membrane protein CreD
H0E72_RS02825	COG0745	RESPONSE REGULATOR receiver
H0E72_RS02835	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
H0E72_RS02845	COG0527	aspartate kinase activity
H0E72_RS02845	COG0460	homoserine dehydrogenase
H0E72_RS02855	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H0E72_RS02870	COG1115	amino acid carrier protein
H0E72_RS02875	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H0E72_RS02880	COG0521	Mo-molybdopterin cofactor biosynthetic process
H0E72_RS02885	COG1584	GPR1 FUN34 yaaH family protein
H0E72_RS02890	COG4735	regulation of single-species biofilm formation
H0E72_RS02920	COG0583	DNA-binding transcription factor activity
H0E72_RS02950	COG0196	riboflavin kinase activity
H0E72_RS02965	COG1047	Peptidyl-prolyl cis-trans
H0E72_RS02985	COG0505	Belongs to the CarA family
H0E72_RS02990	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
H0E72_RS03040	COG0644	oxidoreductase
H0E72_RS03050	COG2271	Major facilitator Superfamily
H0E72_RS03065	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H0E72_RS03090	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H0E72_RS03095	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
H0E72_RS03100	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
H0E72_RS03105	COG0564	pseudouridine synthase activity
H0E72_RS03115	COG0417	DNA replication proofreading
H0E72_RS03120	COG0235	Class ii aldolase
H0E72_RS03130	COG1069	ribulokinase activity
H0E72_RS03135	COG4977	sequence-specific DNA binding
H0E72_RS03140	COG0586	Pfam SNARE associated Golgi protein
H0E72_RS03150	COG1178	ABC-type Fe3 transport system permease component
H0E72_RS03155	COG4143	(ABC) transporter
H0E72_RS03170	COG2814	Major facilitator Superfamily
H0E72_RS03185	COG0473	3-isopropylmalate dehydrogenase activity
H0E72_RS03200	COG0583	DNA-binding transcription factor activity
H0E72_RS03210	COG0028	Belongs to the TPP enzyme family
H0E72_RS03215	COG0440	acetolactate synthase activity
H0E72_RS03225	COG1609	Transcriptional regulator
H0E72_RS03240	COG3116	cell division
H0E72_RS03245	COG0768	penicillin binding
H0E72_RS03250	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H0E72_RS03255	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H0E72_RS03265	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
H0E72_RS03270	COG0772	Belongs to the SEDS family
H0E72_RS03285	COG1181	Belongs to the D-alanine--D-alanine ligase family
H0E72_RS03290	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H0E72_RS03295	COG0849	cell division
H0E72_RS03300	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H0E72_RS03320	COG0494	nUDIX hydrolase
H0E72_RS03335	COG0237	dephospho-CoA kinase activity
H0E72_RS03350	COG1459	type II secretion system
H0E72_RS03355	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H0E72_RS03360	COG4969	Belongs to the N-Me-Phe pilin family
H0E72_RS03365	COG0157	Belongs to the NadC ModD family
H0E72_RS03370	COG3023	N-Acetylmuramoyl-L-alanine amidase
H0E72_RS03375	COG3725	Membrane protein required for beta-lactamase induction
H0E72_RS03380	COG1113	amino acid transport
H0E72_RS03385	COG2186	Transcriptional regulator
H0E72_RS03390	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
H0E72_RS03395	COG0508	dehydrogenase complex catalyzes the overall conversion of
H0E72_RS03400	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H0E72_RS03405	COG3064	Membrane
H0E72_RS03410	COG1049	propionate catabolic process, 2-methylcitrate cycle
H0E72_RS03435	COG2132	Multicopper oxidase
H0E72_RS03440	COG4993	Dehydrogenase
H0E72_RS03445	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
H0E72_RS03450	COG0288	reversible hydration of carbon dioxide
H0E72_RS03455	COG1131	(ABC) transporter
H0E72_RS03460	COG0842	Transport permease protein
H0E72_RS03465	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
H0E72_RS03470	COG0726	polysaccharide deacetylase
H0E72_RS03480	COG5464	transposase or invertase
H0E72_RS03510	COG3539	Fimbrial protein
H0E72_RS03515	COG3539	Fimbrial protein
H0E72_RS03520	COG3539	Fimbrial protein
H0E72_RS03525	COG3188	usher protein
H0E72_RS03530	COG3121	Chaperone
H0E72_RS03535	COG3539	Fimbrial protein
H0E72_RS03540	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H0E72_RS03545	COG0617	tRNA 3'-terminal CCA addition
H0E72_RS03555	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H0E72_RS03565	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
H0E72_RS03570	COG1643	Atp-dependent helicase
H0E72_RS03575	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H0E72_RS03580	COG4774	siderophore transport
H0E72_RS03585	COG1120	ATPase activity
H0E72_RS03590	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H0E72_RS03595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H0E72_RS03620	COG2860	membrane
H0E72_RS03625	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H0E72_RS03640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H0E72_RS03645	COG3835	regulator
H0E72_RS03665	COG0024	Methionine aminopeptidase
H0E72_RS03690	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
H0E72_RS03695	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H0E72_RS03700	COG0575	Belongs to the CDS family
H0E72_RS03705	COG0750	zinc metalloprotease
H0E72_RS03715	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
H0E72_RS03720	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H0E72_RS03745	COG0587	DNA-directed DNA polymerase activity
H0E72_RS03760	COG0346	lactoylglutathione lyase activity
H0E72_RS03765	COG0037	tRNA processing
H0E72_RS03770	COG4568	rho-dependent transcription termination
H0E72_RS03780	COG4681	YaeQ
H0E72_RS03785	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
H0E72_RS03790	COG3015	lipoprotein NlpE involved in copper resistance
H0E72_RS03795	COG0791	NLP P60 protein
H0E72_RS03805	COG1720	tRNA m6t6A37 methyltransferase activity
H0E72_RS03815	COG1464	Belongs to the NlpA lipoprotein family
H0E72_RS03820	COG2011	ABC-type metal ion transport system permease component
H0E72_RS03830	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
H0E72_RS03865	COG0656	L-ascorbic acid biosynthetic process
H0E72_RS03870	COG0583	DNA-binding transcription factor activity
H0E72_RS03880	COG2226	methyltransferase
H0E72_RS03885	COG1388	LysM domain
H0E72_RS03885	COG0741	lytic transglycosylase activity
H0E72_RS03895	COG2226	methyltransferase
H0E72_RS03905	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H0E72_RS03915	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H0E72_RS03925	COG1960	acyl-CoA dehydrogenase activity
H0E72_RS03935	COG0121	glutamine amidotransferase
H0E72_RS03940	COG3034	peptidoglycan biosynthetic process
H0E72_RS03950	COG3077	Addiction module antitoxin, RelB DinJ family
H0E72_RS03955	COG0791	NLP P60 protein
H0E72_RS03960	COG1943	Transposase
H0E72_RS03980	COG1987	bacterial-type flagellum assembly
H0E72_RS04005	COG1677	Flagellar hook-basal body complex protein FliE
H0E72_RS04015	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H0E72_RS04035	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
H0E72_RS04075	COG1815	bacterial-type flagellum-dependent cell motility
H0E72_RS04080	COG1558	bacterial-type flagellum-dependent cell motility
H0E72_RS04090	COG1749	Flagellar hook protein flgE
H0E72_RS04095	COG4787	bacterial-type flagellum-dependent cell motility
H0E72_RS04100	COG4786	Flagellar basal body rod
H0E72_RS04125	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H0E72_RS04140	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H0E72_RS04145	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
H0E72_RS04170	COG1191	sigma factor activity
H0E72_RS04175	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
H0E72_RS04190	COG2161	toxin-antitoxin pair type II binding
H0E72_RS04200	COG0454	-acetyltransferase
H0E72_RS04205	COG1690	Belongs to the RtcB family
H0E72_RS04210	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
H0E72_RS04215	COG2195	Cleaves the N-terminal amino acid of tripeptides
H0E72_RS04235	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
H0E72_RS04255	COG0582	viral genome integration into host DNA
H0E72_RS04295	COG2003	Belongs to the UPF0758 family
H0E72_RS04315	COG3477	response to acidic pH
H0E72_RS04320	COG0727	PFAM Uncharacterised protein family (UPF0153)
H0E72_RS04375	COG1902	pentaerythritol trinitrate reductase activity
H0E72_RS04380	COG1073	alpha beta
H0E72_RS04385	COG0583	DNA-binding transcription factor activity
H0E72_RS04395	COG0667	Aldo Keto reductase
H0E72_RS04400	COG0656	L-ascorbic acid biosynthetic process
H0E72_RS04405	COG1388	LysM domain
H0E72_RS04410	COG3708	Transcriptional regulator
H0E72_RS04410	COG2207	Transcriptional regulator
H0E72_RS04415	COG0656	L-ascorbic acid biosynthetic process
H0E72_RS04420	COG3059	membrane
H0E72_RS04430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H0E72_RS04435	COG2207	Transcriptional regulator
H0E72_RS04440	COG0247	lactate metabolic process
H0E72_RS04445	COG1139	Iron-sulfur cluster binding protein
H0E72_RS04450	COG1556	Lactate utilization protein
H0E72_RS04475	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H0E72_RS04480	COG2200	EAL domain
H0E72_RS04480	COG2771	luxR family
H0E72_RS04485	COG0583	DNA-binding transcription factor activity
H0E72_RS04495	COG0666	response to abiotic stimulus
H0E72_RS04505	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H0E72_RS04510	COG1304	FMN binding
H0E72_RS04515	COG0549	Belongs to the carbamate kinase family
H0E72_RS04520	COG0402	S-adenosylhomocysteine deaminase activity
H0E72_RS04525	COG1064	alcohol dehydrogenase
H0E72_RS04540	COG1280	lysine exporter protein (LysE YggA)
H0E72_RS04550	COG3829	transcription factor binding
H0E72_RS04555	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
H0E72_RS04560	COG0372	Belongs to the citrate synthase family
H0E72_RS04565	COG2079	MmgE PrpD family protein
H0E72_RS04570	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H0E72_RS04575	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H0E72_RS04580	COG0402	S-adenosylhomocysteine deaminase activity
H0E72_RS04585	COG0583	DNA-binding transcription factor activity
H0E72_RS04590	COG0288	reversible hydration of carbon dioxide
H0E72_RS04600	COG2807	transmembrane transport
H0E72_RS04605	COG0110	maltose O-acetyltransferase activity
H0E72_RS04610	COG2223	nitrite transmembrane transporter activity
H0E72_RS04620	COG1609	Transcriptional regulator
H0E72_RS04625	COG1414	Transcriptional regulator
H0E72_RS04660	COG2814	Major facilitator Superfamily
H0E72_RS04665	COG3122	Protein conserved in bacteria
H0E72_RS04695	COG1215	transferase activity, transferring glycosyl groups
H0E72_RS04700	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
H0E72_RS04705	COG4521	taurine ABC transporter
H0E72_RS04715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H0E72_RS04720	COG2175	clavaminate synthase activity
H0E72_RS04725	COG0113	porphobilinogen synthase activity
H0E72_RS04745	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H0E72_RS04750	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H0E72_RS04755	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
H0E72_RS04775	COG1181	Belongs to the D-alanine--D-alanine ligase family
H0E72_RS04790	COG1785	Belongs to the alkaline phosphatase family
H0E72_RS04800	COG3706	GGDEF domain
H0E72_RS04805	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H0E72_RS04825	COG4126	flavin adenine dinucleotide binding
H0E72_RS04850	COG1940	carbohydrate kinase activity
H0E72_RS04855	COG2814	Major facilitator Superfamily
H0E72_RS04860	COG0419	ATPase involved in DNA repair
H0E72_RS04865	COG0420	3'-5' exonuclease activity
H0E72_RS04870	COG0745	RESPONSE REGULATOR receiver
H0E72_RS04875	COG5002	protein histidine kinase activity
H0E72_RS04880	COG1114	Component of the transport system for branched-chain amino acids
H0E72_RS04885	COG1113	amino acid transport
H0E72_RS04890	COG0366	Alpha amylase catalytic
H0E72_RS04915	COG1862	Preprotein translocase
H0E72_RS04920	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H0E72_RS04925	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H0E72_RS04930	COG3609	addiction module antidote protein, CC2985 family
H0E72_RS04940	COG1403	HNH endonuclease
H0E72_RS04945	COG3248	Nucleoside-binding outer membrane protein
H0E72_RS04960	COG0675	Transposase, IS605 OrfB family
H0E72_RS04975	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H0E72_RS04975	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H0E72_RS04990	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H0E72_RS04995	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H0E72_RS05000	COG0667	Aldo Keto reductase
H0E72_RS05010	COG0142	geranyltranstransferase activity
H0E72_RS05025	COG0693	protein deglycase activity
H0E72_RS05030	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H0E72_RS05040	COG2814	Major facilitator Superfamily
H0E72_RS05065	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H0E72_RS05070	COG1845	cytochrome c oxidase, subunit III
H0E72_RS05075	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H0E72_RS05080	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H0E72_RS05085	COG2223	nitrite transmembrane transporter activity
H0E72_RS05090	COG3056	Lipoprotein
H0E72_RS05095	COG0271	Belongs to the BolA IbaG family
H0E72_RS05115	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
H0E72_RS05120	COG0776	regulation of translation
H0E72_RS05125	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H0E72_RS05130	COG1555	photosystem II stabilization
H0E72_RS05135	COG0824	Thioesterase
H0E72_RS05145	COG4533	DNA binding
H0E72_RS05155	COG1522	sequence-specific DNA binding
H0E72_RS05160	COG1132	(ABC) transporter
H0E72_RS05165	COG1132	(ABC) transporter
H0E72_RS05170	COG0347	Belongs to the P(II) protein family
H0E72_RS05175	COG0004	ammonium transporteR
H0E72_RS05180	COG1946	Acyl-CoA thioesterase
H0E72_RS05185	COG3126	Type III secretion system lipoprotein chaperone (YscW)
H0E72_RS05190	COG3695	enzyme binding
H0E72_RS05200	COG5507	3-demethylubiquinone-9 3-methyltransferase
H0E72_RS05205	COG4943	cyclic-guanylate-specific phosphodiesterase activity
H0E72_RS05215	COG0110	maltose O-acetyltransferase activity
H0E72_RS05230	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H0E72_RS05235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0E72_RS05240	COG1309	transcriptional regulator
H0E72_RS05245	COG1196	nuclear chromosome segregation
H0E72_RS05245	COG3264	Mechanosensitive ion channel
H0E72_RS05255	COG3923	Primosomal replication protein n
H0E72_RS05260	COG2832	Protein of unknown function (DUF454)
H0E72_RS05270	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H0E72_RS05305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H0E72_RS05310	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H0E72_RS05310	COG4651	solute:proton antiporter activity
H0E72_RS05315	COG2223	nitrite transmembrane transporter activity
H0E72_RS05320	COG0737	Belongs to the 5'-nucleotidase family
H0E72_RS05325	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H0E72_RS05330	COG3735	TraB family
H0E72_RS05335	COG2217	Heavy metal translocating P-type atpase
H0E72_RS05345	COG0531	amino acid
H0E72_RS05350	COG0789	Transcriptional regulator
H0E72_RS05375	COG1585	Membrane protein implicated in regulation of membrane protease activity
H0E72_RS05380	COG0330	HflC and HflK could
H0E72_RS05385	COG4619	ABC transporter
H0E72_RS05390	COG0390	transport system, permease component
H0E72_RS05395	COG3118	belongs to the thioredoxin family
H0E72_RS05400	COG0300	oxidoreductase activity
H0E72_RS05405	COG2755	lipolytic protein G-D-S-L family
H0E72_RS05410	COG4181	ATPase activity
H0E72_RS05415	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
H0E72_RS05425	COG0583	DNA-binding transcription factor activity
H0E72_RS05435	COG1414	Transcriptional regulator
H0E72_RS05440	COG3960	tartronate-semialdehyde synthase activity
H0E72_RS05445	COG3622	Belongs to the hyi family
H0E72_RS05450	COG2084	Dehydrogenase
H0E72_RS05465	COG1929	Belongs to the glycerate kinase type-1 family
H0E72_RS05470	COG3257	ureidoglycine aminohydrolase activity
H0E72_RS05475	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H0E72_RS05480	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
H0E72_RS05485	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H0E72_RS05490	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H0E72_RS05500	COG0549	Belongs to the carbamate kinase family
H0E72_RS05505	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H0E72_RS05510	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
H0E72_RS05520	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H0E72_RS05530	COG1988	membrane-bound metal-dependent
H0E72_RS05535	COG2501	S4 domain
H0E72_RS05545	COG3539	Fimbrial protein
H0E72_RS05550	COG3121	Chaperone
H0E72_RS05555	COG3188	usher protein
H0E72_RS05560	COG3539	Fimbrial protein
H0E72_RS05565	COG3539	Fimbrial protein
H0E72_RS05570	COG2197	response regulator
H0E72_RS05580	COG2207	Transcriptional regulator
H0E72_RS05590	COG4783	chaperone-mediated protein folding
H0E72_RS05595	COG1215	transferase activity, transferring glycosyl groups
H0E72_RS05600	COG5002	protein histidine kinase activity
H0E72_RS05605	COG0745	RESPONSE REGULATOR receiver
H0E72_RS05610	COG1538	Outer membrane efflux protein
H0E72_RS05615	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0E72_RS05620	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0E72_RS05625	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H0E72_RS05630	COG1113	amino acid transport
H0E72_RS05635	COG0668	transmembrane transport
H0E72_RS05640	COG0778	Nitroreductase
H0E72_RS05645	COG2315	Protein conserved in bacteria
H0E72_RS05665	COG2977	Belongs to the P-Pant transferase superfamily
H0E72_RS05670	COG4771	TonB-dependent receptor
H0E72_RS05675	COG2382	esterase
H0E72_RS05680	COG3251	PFAM MbtH domain protein
H0E72_RS05685	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
H0E72_RS05685	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H0E72_RS05690	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
H0E72_RS05695	COG1120	ATPase activity
H0E72_RS05700	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H0E72_RS05705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H0E72_RS05715	COG4592	Periplasmic binding protein
H0E72_RS05720	COG1169	isochorismate synthase
H0E72_RS05725	COG1021	2,3-dihydroxybenzoate-AMP ligase
H0E72_RS05730	COG3433	isochorismatase activity
H0E72_RS05730	COG1535	isochorismatase
H0E72_RS05735	COG1028	Short-chain dehydrogenase reductase Sdr
H0E72_RS05740	COG2050	protein possibly involved in aromatic compounds catabolism
H0E72_RS05745	COG1966	Carbon starvation protein
H0E72_RS05750	COG2879	small protein
H0E72_RS05755	COG0371	Dehydrogenase
H0E72_RS05760	COG0436	Aminotransferase
H0E72_RS05765	COG1475	DNA binding
H0E72_RS05770	COG3969	phosphoadenosine phosphosulfate
H0E72_RS05775	COG0583	DNA-binding transcription factor activity
H0E72_RS05780	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H0E72_RS05785	COG0450	alkyl hydroperoxide reductase
H0E72_RS05790	COG3634	alkyl hydroperoxide reductase activity
H0E72_RS05795	COG0589	response to stress
H0E72_RS05800	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H0E72_RS05805	COG3719	Belongs to the RNase T2 family
H0E72_RS05810	COG0471	metal ion transport
H0E72_RS05825	COG3051	citrate lyase alpha subunit
H0E72_RS05830	COG2301	Belongs to the HpcH HpaI aldolase family
H0E72_RS05840	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
H0E72_RS05845	COG3290	protein histidine kinase activity
H0E72_RS05850	COG4565	transcriptional regulatory protein
H0E72_RS05855	COG3069	C4-dicarboxylate transmembrane transporter activity
H0E72_RS05875	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H0E72_RS05880	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H0E72_RS05890	COG0583	DNA-binding transcription factor activity
H0E72_RS05905	COG1686	Belongs to the peptidase S11 family
H0E72_RS05910	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H0E72_RS05915	COG0772	Belongs to the SEDS family
H0E72_RS05920	COG0768	penicillin binding
H0E72_RS05930	COG0799	negative regulation of ribosome biogenesis
H0E72_RS05935	COG0406	alpha-ribazole phosphatase activity
H0E72_RS05945	COG1466	dna polymerase III delta subunit
H0E72_RS05960	COG2888	peptidyl-tyrosine sulfation
H0E72_RS05965	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
H0E72_RS05975	COG2214	Heat shock protein DnaJ domain protein
H0E72_RS05980	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
H0E72_RS05990	COG2214	Heat shock protein DnaJ domain protein
H0E72_RS05995	COG0443	Heat shock 70 kDa protein
H0E72_RS06005	COG1126	abc transporter atp-binding protein
H0E72_RS06010	COG0765	amino acid transport
H0E72_RS06015	COG0765	amino acid transport
H0E72_RS06020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H0E72_RS06025	COG0815	Transfers the fatty acyl group on membrane lipoproteins
H0E72_RS06030	COG4535	Mg2 and Co2 transporter CorC
H0E72_RS06040	COG1702	phosphate starvation-inducible protein PhoH
H0E72_RS06050	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H0E72_RS06090	COG0367	asparagine synthase
H0E72_RS06095	COG0647	UMP catabolic process
H0E72_RS06100	COG1846	Transcriptional regulator
H0E72_RS06100	COG1940	carbohydrate kinase activity
H0E72_RS06105	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
H0E72_RS06115	COG1263	PTS System
H0E72_RS06115	COG2190	(PTS) system
H0E72_RS06115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H0E72_RS06135	COG0735	belongs to the Fur family
H0E72_RS06145	COG0716	FMN binding
H0E72_RS06155	COG0596	Alpha beta hydrolase
H0E72_RS06160	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
H0E72_RS06165	COG0033	Phosphoglucomutase
H0E72_RS06180	COG0531	amino acid
H0E72_RS06185	COG1982	Orn Lys Arg decarboxylase major
H0E72_RS06195	COG0745	RESPONSE REGULATOR receiver
H0E72_RS06200	COG2205	protein histidine kinase activity
H0E72_RS06230	COG3272	Protein of unknown function (DUF1722)
H0E72_RS06235	COG0415	Belongs to the DNA photolyase family
H0E72_RS06245	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H0E72_RS06250	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
H0E72_RS06255	COG1984	allophanate hydrolase subunit 2
H0E72_RS06270	COG3180	Ammonia monooxygenase
H0E72_RS06280	COG0372	Belongs to the citrate synthase family
H0E72_RS06290	COG2009	succinate dehydrogenase
H0E72_RS06295	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
H0E72_RS06300	COG1053	succinate dehydrogenase
H0E72_RS06305	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H0E72_RS06310	COG0567	Dehydrogenase, E1 component
H0E72_RS06315	COG0508	dehydrogenase complex catalyzes the overall conversion of
H0E72_RS06325	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H0E72_RS06330	COG0583	DNA-binding transcription factor activity
H0E72_RS06335	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
H0E72_RS06340	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
H0E72_RS06340	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H0E72_RS06345	COG1301	dicarboxylic acid transport
H0E72_RS06360	COG3799	methylaspartate ammonia-lyase activity
H0E72_RS06365	COG4865	methylaspartate mutase activity
H0E72_RS06375	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
H0E72_RS06390	COG1271	oxidase subunit
H0E72_RS06395	COG1294	oxidase, subunit
H0E72_RS06400	COG4890	Cyd operon protein YbgT
H0E72_RS06405	COG3790	cyd operon protein YbgE
H0E72_RS06410	COG0824	Thioesterase
H0E72_RS06415	COG0811	peptide transport
H0E72_RS06420	COG0848	biopolymer transport protein
H0E72_RS06425	COG3064	Membrane
H0E72_RS06435	COG2885	chlorophyll binding
H0E72_RS06440	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
H0E72_RS06485	COG3201	nicotinamide mononucleotide transporter
H0E72_RS06500	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H0E72_RS06510	COG2017	converts alpha-aldose to the beta-anomer
H0E72_RS06520	COG1085	galactose-1-phosphate uridylyltransferase
H0E72_RS06525	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H0E72_RS06530	COG1119	ATPase activity
H0E72_RS06535	COG3585	molybdate ion transport
H0E72_RS06535	COG2005	Transcriptional regulator
H0E72_RS06545	COG0725	ABC transporter, periplasmic molybdate-binding protein
H0E72_RS06550	COG4149	molybdate abc transporter
H0E72_RS06560	COG0561	phosphatase activity
H0E72_RS06570	COG0583	DNA-binding transcription factor activity
H0E72_RS06575	COG2828	Protein conserved in bacteria
H0E72_RS06580	COG0471	metal ion transport
H0E72_RS06585	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H0E72_RS06590	COG4677	pectinesterase activity
H0E72_RS06595	COG1881	PFAM PEBP family protein
H0E72_RS06600	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H0E72_RS06615	COG2226	methyltransferase
H0E72_RS06620	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
H0E72_RS06630	COG0391	Required for morphogenesis under gluconeogenic growth conditions
H0E72_RS06640	COG0521	Mo-molybdopterin cofactor biosynthetic process
H0E72_RS06650	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
H0E72_RS06655	COG0314	molybdopterin synthase activity
H0E72_RS06660	COG0670	Belongs to the BI1 family
H0E72_RS06665	COG0670	Belongs to the BI1 family
H0E72_RS06670	COG0392	lysyltransferase activity
H0E72_RS06675	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H0E72_RS06680	COG3568	Endonuclease Exonuclease Phosphatase
H0E72_RS06690	COG0842	Transport permease protein
H0E72_RS06695	COG0842	Transport permease protein
H0E72_RS06700	COG1131	(ABC) transporter
H0E72_RS06710	COG1309	transcriptional regulator
H0E72_RS06715	COG0513	Belongs to the DEAD box helicase family
H0E72_RS06730	COG1199	ATP-dependent helicase activity
H0E72_RS06735	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H0E72_RS06740	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
H0E72_RS06750	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H0E72_RS06775	COG0668	transmembrane transport
H0E72_RS06780	COG1126	abc transporter atp-binding protein
H0E72_RS06785	COG0765	amino acid transport
H0E72_RS06790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H0E72_RS06800	COG5006	permease, DMT superfamily
H0E72_RS06810	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H0E72_RS06815	COG2194	sulfuric ester hydrolase activity
H0E72_RS06825	COG1321	iron dependent repressor
H0E72_RS06830	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
H0E72_RS06835	COG1376	ErfK ybiS ycfS ynhG family protein
H0E72_RS06840	COG0488	(ABC) transporter
H0E72_RS06850	COG0561	phosphatase activity
H0E72_RS06855	COG1882	Formate acetyltransferase
H0E72_RS06860	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H0E72_RS06865	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H0E72_RS06870	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H0E72_RS06875	COG0303	'Molybdopterin
H0E72_RS06880	COG1446	asparaginase
H0E72_RS06890	COG0747	negative chemotaxis
H0E72_RS06905	COG2200	EAL domain
H0E72_RS06910	COG2199	diguanylate cyclase activity
H0E72_RS06935	COG2133	pyrroloquinoline quinone binding
H0E72_RS06940	COG0625	glutathione transferase activity
H0E72_RS06945	COG1686	Belongs to the peptidase S11 family
H0E72_RS06950	COG1349	DNA-binding transcription factor activity
H0E72_RS06955	COG0671	phosphoesterase, PA-phosphatase related
H0E72_RS06960	COG2814	Major facilitator Superfamily
H0E72_RS06970	COG0561	phosphatase activity
H0E72_RS06975	COG0738	Major facilitator superfamily
H0E72_RS06980	COG3226	Transcriptional regulator
H0E72_RS06995	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H0E72_RS07005	COG0778	Nitroreductase
H0E72_RS07020	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
H0E72_RS07025	COG3842	ATPase activity
H0E72_RS07030	COG1176	ABC-type spermidine putrescine transport system, permease component I
H0E72_RS07035	COG1177	transmembrane transport
H0E72_RS07050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H0E72_RS07055	COG4160	amino acid transport
H0E72_RS07060	COG4215	(ABC) transporter
H0E72_RS07065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H0E72_RS07070	COG1126	abc transporter atp-binding protein
H0E72_RS07090	COG3023	N-Acetylmuramoyl-L-alanine amidase
H0E72_RS07095	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H0E72_RS07100	COG0702	epimerase
H0E72_RS07105	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
H0E72_RS07110	COG0028	Belongs to the TPP enzyme family
H0E72_RS07115	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H0E72_RS07125	COG2431	L-lysine efflux transmembrane transporter activity
H0E72_RS07145	COG1028	Short-chain dehydrogenase reductase Sdr
H0E72_RS07150	COG0586	Pfam SNARE associated Golgi protein
H0E72_RS07160	COG1686	Belongs to the peptidase S11 family
H0E72_RS07165	COG0277	FAD linked oxidase domain protein
H0E72_RS07170	COG1472	Belongs to the glycosyl hydrolase 3 family
H0E72_RS07175	COG1732	Glycine betaine
H0E72_RS07180	COG1174	glycine betaine transport
H0E72_RS07185	COG1125	glycine betaine transport
H0E72_RS07190	COG1174	glycine betaine transport
H0E72_RS07200	COG0789	Transcriptional regulator
H0E72_RS07205	COG3275	phosphorelay sensor kinase activity
H0E72_RS07210	COG3279	Response regulator of the LytR AlgR family
H0E72_RS07215	COG4807	Protein conserved in bacteria
H0E72_RS07220	COG4808	Protein conserved in bacteria
H0E72_RS07225	COG4715	Zinc finger, swim domain protein
H0E72_RS07230	COG3552	Protein containing von Willebrand factor type A (VWA) domain
H0E72_RS07235	COG2425	protein containing a von Willebrand factor type A (vWA) domain
H0E72_RS07240	COG0714	Associated with various cellular activities
H0E72_RS07250	COG3831	ATPase activity
H0E72_RS07255	COG3831	ATPase activity
H0E72_RS07265	COG0489	protein tyrosine kinase activity
H0E72_RS07275	COG3539	Fimbrial protein
H0E72_RS07280	COG3121	Chaperone
H0E72_RS07285	COG3188	usher protein
H0E72_RS07290	COG3539	Fimbrial protein
H0E72_RS07295	COG5455	response to cobalt ion
H0E72_RS07400	COG4626	Terminase
H0E72_RS07400	COG1802	Transcriptional regulator
H0E72_RS07415	COG0351	phosphomethylpyrimidine kinase
H0E72_RS07420	COG3757	hydrolase, family 25
H0E72_RS07425	COG2188	Transcriptional regulator
H0E72_RS07430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H0E72_RS07435	COG1397	ADP-ribosylglycohydrolase
H0E72_RS07440	COG2211	Major facilitator Superfamily
H0E72_RS07445	COG1830	Aldolase
H0E72_RS07460	COG3039	Transposase
H0E72_RS07485	COG4974	Belongs to the 'phage' integrase family
H0E72_RS07540	COG4695	Portal protein
H0E72_RS07700	COG3609	addiction module antidote protein, CC2985 family
H0E72_RS07710	COG0745	RESPONSE REGULATOR receiver
H0E72_RS07715	COG2205	protein histidine kinase activity
H0E72_RS07750	COG4245	von Willebrand factor, type A
H0E72_RS07755	COG0631	protein serine/threonine phosphatase activity
H0E72_RS07760	COG3779	Protein conserved in bacteria
H0E72_RS07765	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
H0E72_RS07770	COG0443	Heat shock 70 kDa protein
H0E72_RS07775	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
H0E72_RS07780	COG5001	Diguanylate cyclase
H0E72_RS07780	COG5002	protein histidine kinase activity
H0E72_RS07780	COG3447	MASE1 domain protein
H0E72_RS07785	COG0572	uridine kinase
H0E72_RS07795	COG2982	Protein involved in outer membrane biogenesis
H0E72_RS07810	COG1253	flavin adenine dinucleotide binding
H0E72_RS07820	COG1596	polysaccharide export
H0E72_RS07825	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H0E72_RS07830	COG0489	protein tyrosine kinase activity
H0E72_RS07830	COG3206	protein involved in exopolysaccharide biosynthesis
H0E72_RS07835	COG0463	Glycosyl transferase, family 2
H0E72_RS07840	COG1045	serine acetyltransferase
H0E72_RS07845	COG0438	transferase activity, transferring glycosyl groups
H0E72_RS07855	COG1216	Glycosyl transferase, family 2
H0E72_RS07860	COG0110	maltose O-acetyltransferase activity
H0E72_RS07865	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
H0E72_RS07870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H0E72_RS07875	COG1051	belongs to the nudix hydrolase family
H0E72_RS07880	COG0297	glycogen (starch) synthase activity
H0E72_RS07885	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
H0E72_RS07885	COG0662	Cupin 2, conserved barrel domain protein
H0E72_RS07890	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H0E72_RS07895	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H0E72_RS07900	COG2244	polysaccharide biosynthetic process
H0E72_RS07905	COG2327	Polysaccharide pyruvyl transferase
H0E72_RS07910	COG0438	transferase activity, transferring glycosyl groups
H0E72_RS07920	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H0E72_RS07940	COG4641	Protein conserved in bacteria
H0E72_RS07940	COG0438	transferase activity, transferring glycosyl groups
H0E72_RS07960	COG1045	serine acetyltransferase
H0E72_RS07975	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
H0E72_RS07985	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H0E72_RS07985	COG0140	phosphoribosyl-ATP diphosphatase activity
H0E72_RS08000	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H0E72_RS08005	COG0131	Imidazoleglycerol-phosphate dehydratase
H0E72_RS08005	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
H0E72_RS08015	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H0E72_RS08030	COG2161	toxin-antitoxin pair type II binding
H0E72_RS08035	COG4115	mRNA cleavage
H0E72_RS08040	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H0E72_RS08045	COG0583	DNA-binding transcription factor activity
H0E72_RS08055	COG0531	amino acid
H0E72_RS08060	COG2391	methyltransferase activity
H0E72_RS08065	COG0425	Belongs to the sulfur carrier protein TusA family
H0E72_RS08070	COG2925	Exonuclease
H0E72_RS08075	COG1686	Belongs to the peptidase S11 family
H0E72_RS08085	COG1289	transmembrane transporter activity
H0E72_RS08130	COG2003	Belongs to the UPF0758 family
H0E72_RS08235	COG1735	metal-dependent hydrolase with the TIM-barrel fold
H0E72_RS08265	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
H0E72_RS08280	COG1376	ErfK ybiS ycfS ynhG family protein
H0E72_RS08290	COG0583	DNA-binding transcription factor activity
H0E72_RS08295	COG0583	DNA-binding transcription factor activity
H0E72_RS08305	COG0534	Mate efflux family protein
H0E72_RS08315	COG0217	transcriptional regulatory protein
H0E72_RS08320	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H0E72_RS08325	COG0477	Major facilitator Superfamily
H0E72_RS08340	COG2373	Large extracellular alpha-helical protein
H0E72_RS08340	COG4932	domain protein
H0E72_RS08340	COG1388	LysM domain
H0E72_RS08345	COG4771	TonB-dependent receptor
H0E72_RS08350	COG1021	2,3-dihydroxybenzoate-AMP ligase
H0E72_RS08370	COG3433	isochorismatase activity
H0E72_RS08370	COG2226	methyltransferase
H0E72_RS08370	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H0E72_RS08385	COG1132	(ABC) transporter
H0E72_RS08390	COG2814	Major facilitator Superfamily
H0E72_RS08395	COG1169	isochorismate synthase
H0E72_RS08430	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H0E72_RS08465	COG1396	sequence-specific DNA binding
H0E72_RS08535	COG1403	HNH endonuclease
H0E72_RS08540	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
H0E72_RS08575	COG3772	lysozyme
H0E72_RS08615	COG4695	Portal protein
H0E72_RS08700	COG5301	cellulose 1,4-beta-cellobiosidase activity
H0E72_RS08720	COG3443	Belongs to the bacterial solute-binding protein 9 family
H0E72_RS08735	COG2351	hydroxyisourate hydrolase activity
H0E72_RS08740	COG0745	RESPONSE REGULATOR receiver
H0E72_RS08745	COG2205	protein histidine kinase activity
H0E72_RS08765	COG0270	DNA (cytosine-5-)-methyltransferase activity
H0E72_RS08770	COG3727	T/G mismatch-specific endonuclease activity
H0E72_RS08775	COG0697	spore germination
H0E72_RS08780	COG2354	Protein conserved in bacteria
H0E72_RS08785	COG5475	Uncharacterized small protein (DUF2158)
H0E72_RS08810	COG2197	response regulator
H0E72_RS08815	COG1684	flagellar biosynthetic protein fliR
H0E72_RS08820	COG1987	bacterial-type flagellum assembly
H0E72_RS08825	COG1338	Plays a role in the flagellum-specific transport system
H0E72_RS08830	COG3190	flagellar
H0E72_RS08835	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H0E72_RS08840	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H0E72_RS08845	COG1580	Controls the rotational direction of flagella during chemotaxis
H0E72_RS08850	COG3144	bacterial-type flagellum assembly
H0E72_RS08855	COG2882	bacterial-type flagellum organization
H0E72_RS08860	COG1157	protein secretion by the type III secretion system
H0E72_RS08865	COG1317	bacterial-type flagellum organization
H0E72_RS08870	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H0E72_RS08875	COG1766	The M ring may be actively involved in energy transduction
H0E72_RS08885	COG2076	Multidrug Resistance protein
H0E72_RS08890	COG1881	PFAM PEBP family protein
H0E72_RS08895	COG2207	Transcriptional regulator
H0E72_RS08905	COG0675	Transposase, IS605 OrfB family
H0E72_RS08910	COG2135	peptidase activity
H0E72_RS08915	COG0425	Belongs to the sulfur carrier protein TusA family
H0E72_RS08920	COG2391	methyltransferase activity
H0E72_RS08930	COG0366	Alpha amylase catalytic
H0E72_RS08940	COG1516	flagellar protein fliS
H0E72_RS08945	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
H0E72_RS08955	COG1191	sigma factor activity
H0E72_RS08985	COG2197	response regulator
H0E72_RS09000	COG2197	response regulator
H0E72_RS09030	COG3318	Belongs to the UPF0149 family
H0E72_RS09030	COG3012	SEC-C Motif Domain Protein
H0E72_RS09035	COG0814	amino acid
H0E72_RS09045	COG1528	Iron-storage protein
H0E72_RS09065	COG1528	Iron-storage protein
H0E72_RS09070	COG1879	ABC-type sugar transport system periplasmic component
H0E72_RS09075	COG1129	ABC transporter
H0E72_RS09080	COG1172	Belongs to the binding-protein-dependent transport system permease family
H0E72_RS09085	COG1877	trehalose-phosphatase activity
H0E72_RS09095	COG0589	response to stress
H0E72_RS09110	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
H0E72_RS09115	COG1360	Flagellar Motor Protein
H0E72_RS09120	COG0643	Histidine kinase
H0E72_RS09120	COG2198	Histidine kinase
H0E72_RS09125	COG0835	chemotaxis
H0E72_RS09130	COG0840	transmembrane signaling receptor activity
H0E72_RS09135	COG0840	transmembrane signaling receptor activity
H0E72_RS09140	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
H0E72_RS09150	COG0745	RESPONSE REGULATOR receiver
H0E72_RS09155	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
H0E72_RS09160	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
H0E72_RS09165	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
H0E72_RS09180	COG3102	Protein conserved in bacteria
H0E72_RS09190	COG3005	denitrification pathway
H0E72_RS09195	COG0243	molybdopterin cofactor binding
H0E72_RS09210	COG3788	relative of glutathione S-transferase, MAPEG superfamily
H0E72_RS09215	COG1801	Protein of unknown function DUF72
H0E72_RS09220	COG1335	isochorismatase
H0E72_RS09230	COG0494	nUDIX hydrolase
H0E72_RS09235	COG0217	transcriptional regulatory protein
H0E72_RS09265	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H0E72_RS09275	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
H0E72_RS09280	COG0739	heme binding
H0E72_RS09285	COG1560	Kdo2-lipid A biosynthetic process
H0E72_RS09290	COG0469	pyruvate kinase activity
H0E72_RS09295	COG1737	Transcriptional regulator
H0E72_RS09300	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
H0E72_RS09305	COG0129	dihydroxy-acid dehydratase activity
H0E72_RS09310	COG0800	Aldolase
H0E72_RS09320	COG3141	response to X-ray
H0E72_RS09330	COG2979	Protein of unknown function (DUF533)
H0E72_RS09335	COG1770	oligopeptidase
H0E72_RS09340	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H0E72_RS09345	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H0E72_RS09355	COG2372	response to copper ion
H0E72_RS09360	COG1276	copper resistance
H0E72_RS09370	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H0E72_RS09390	COG3008	intermembrane lipid transfer
H0E72_RS09395	COG2995	paraquat-inducible protein a
H0E72_RS09400	COG1956	GAF domain-containing protein
H0E72_RS09410	COG0793	Belongs to the peptidase S41A family
H0E72_RS09420	COG2814	Major facilitator Superfamily
H0E72_RS09425	COG1414	Transcriptional regulator
H0E72_RS09455	COG2226	methyltransferase
H0E72_RS09470	COG3716	PTS system mannose fructose sorbose family IID component
H0E72_RS09475	COG3715	PTS system
H0E72_RS09480	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H0E72_RS09480	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
H0E72_RS09485	COG1253	flavin adenine dinucleotide binding
H0E72_RS09490	COG2200	EAL domain
H0E72_RS09495	COG1760	l-serine dehydratase
H0E72_RS09505	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H0E72_RS09520	COG0251	oxidation-reduction process
H0E72_RS09525	COG1199	ATP-dependent helicase activity
H0E72_RS09530	COG1214	PFAM Peptidase M22, glycoprotease
H0E72_RS09535	COG3065	identical protein binding
H0E72_RS09540	COG0318	PFAM AMP-dependent synthetase and ligase
H0E72_RS09545	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
H0E72_RS09550	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H0E72_RS09555	COG4638	Rieske (2fe-2S)
H0E72_RS09560	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H0E72_RS09565	COG0473	3-isopropylmalate dehydrogenase activity
H0E72_RS09570	COG0583	DNA-binding transcription factor activity
H0E72_RS09580	COG3615	Tellurite resistance protein tehB
H0E72_RS09590	COG2261	transglycosylase associated protein
H0E72_RS09605	COG2203	Gaf domain
H0E72_RS09605	COG2199	diguanylate cyclase activity
H0E72_RS09610	COG3042	response to heat
H0E72_RS09615	COG3189	MarR family transcriptional regulator
H0E72_RS09620	COG2807	transmembrane transport
H0E72_RS09625	COG2207	Transcriptional regulator
H0E72_RS09640	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H0E72_RS09645	COG2199	diguanylate cyclase activity
H0E72_RS09650	COG2199	diguanylate cyclase activity
H0E72_RS09660	COG2766	serine protein kinase
H0E72_RS09665	COG3713	MltA-interacting MipA family protein
H0E72_RS09670	COG0656	L-ascorbic acid biosynthetic process
H0E72_RS09675	COG0676	glucose-6-phosphate 1-epimerase activity
H0E72_RS09680	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H0E72_RS09690	COG3139	Protein of unknown function (DUF1315)
H0E72_RS09695	COG1063	alcohol dehydrogenase
H0E72_RS09700	COG2271	Major facilitator Superfamily
H0E72_RS09705	COG1063	alcohol dehydrogenase
H0E72_RS09710	COG0191	fructose-bisphosphate aldolase activity
H0E72_RS09715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H0E72_RS09720	COG0667	Aldo Keto reductase
H0E72_RS09725	COG1349	DNA-binding transcription factor activity
H0E72_RS09730	COG2814	Major facilitator Superfamily
H0E72_RS09735	COG1335	isochorismatase
H0E72_RS09740	COG0252	asparaginase activity
H0E72_RS09745	COG0616	signal peptide processing
H0E72_RS09750	COG0778	Nitroreductase
H0E72_RS09755	COG0709	Synthesizes selenophosphate from selenide and ATP
H0E72_RS09760	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H0E72_RS09765	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H0E72_RS09775	COG0494	nUDIX hydrolase
H0E72_RS09780	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H0E72_RS09785	COG2897	thiosulfate sulfurtransferase activity
H0E72_RS09790	COG4136	ATPase activity
H0E72_RS09795	COG4135	transport system, permease component
H0E72_RS09800	COG4134	Bacterial extracellular solute-binding protein
H0E72_RS09805	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H0E72_RS09810	COG0398	Pfam SNARE associated Golgi protein
H0E72_RS09820	COG0398	Pfam SNARE associated Golgi protein
H0E72_RS09825	COG0708	Exodeoxyribonuclease III
H0E72_RS09855	COG3678	ATP-independent chaperone mediated protein folding
H0E72_RS09865	COG0322	excinuclease ABC activity
H0E72_RS09875	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H0E72_RS09880	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H0E72_RS09885	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H0E72_RS09890	COG1447	Phosphotransferase system cellobiose-specific component IIA
H0E72_RS09895	COG2169	Transcriptional regulator
H0E72_RS09895	COG1917	Cupin 2, conserved barrel domain protein
H0E72_RS09900	COG1486	melibiose metabolic process
H0E72_RS09910	COG0753	catalase activity
H0E72_RS09930	COG1988	membrane-bound metal-dependent
H0E72_RS09935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H0E72_RS09945	COG3001	Fructosamine kinase
H0E72_RS09955	COG1105	Belongs to the carbohydrate kinase PfkB family
H0E72_RS09960	COG3137	Salt-induced outer membrane protein
H0E72_RS10150	COG4695	Portal protein
H0E72_RS10220	COG4974	Belongs to the 'phage' integrase family
H0E72_RS10235	COG0386	Belongs to the glutathione peroxidase family
H0E72_RS10245	COG0791	NLP P60 protein
H0E72_RS10250	COG2200	EAL domain
H0E72_RS10260	COG4256	Hemin uptake protein
H0E72_RS10265	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H0E72_RS10275	COG0574	Belongs to the PEP-utilizing enzyme family
H0E72_RS10275	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H0E72_RS10280	COG0471	metal ion transport
H0E72_RS10285	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H0E72_RS10295	COG1028	Short-chain dehydrogenase reductase Sdr
H0E72_RS10300	COG0318	PFAM AMP-dependent synthetase and ligase
H0E72_RS10305	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
H0E72_RS10310	COG0644	oxidoreductase
H0E72_RS10315	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
H0E72_RS10320	COG2086	electron transfer activity
H0E72_RS10325	COG2207	Transcriptional regulator
H0E72_RS10325	COG1917	Cupin 2, conserved barrel domain protein
H0E72_RS10330	COG1960	acyl-CoA dehydrogenase activity
H0E72_RS10335	COG4670	ketone body catabolic process
H0E72_RS10350	COG2271	Major facilitator Superfamily
H0E72_RS10355	COG0738	Major facilitator superfamily
H0E72_RS10370	COG0628	permease
H0E72_RS10375	COG0277	FAD linked oxidase domain protein
H0E72_RS10375	COG0247	lactate metabolic process
H0E72_RS10380	COG2050	protein possibly involved in aromatic compounds catabolism
H0E72_RS10390	COG0316	Belongs to the HesB IscA family
H0E72_RS10395	COG0719	Fe-S assembly protein
H0E72_RS10400	COG0396	ATPase activity
H0E72_RS10405	COG0719	Fe-S assembly protein
H0E72_RS10430	COG1376	ErfK ybiS ycfS ynhG family protein
H0E72_RS10435	COG4238	major outer membrane lipoprotein
H0E72_RS10440	COG0469	pyruvate kinase activity
H0E72_RS10450	COG0437	4 iron, 4 sulfur cluster binding
H0E72_RS10455	COG2414	aldehyde ferredoxin oxidoreductase
H0E72_RS10465	COG0437	4 iron, 4 sulfur cluster binding
H0E72_RS10470	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
H0E72_RS10500	COG3468	outer membrane autotransporter barrel domain protein
H0E72_RS10510	COG0307	riboflavin synthase, alpha
H0E72_RS10515	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H0E72_RS10520	COG2814	Major facilitator Superfamily
H0E72_RS10525	COG0583	DNA-binding transcription factor activity
H0E72_RS10540	COG2814	Major facilitator Superfamily
H0E72_RS10545	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H0E72_RS10550	COG0791	NLP P60 protein
H0E72_RS10555	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H0E72_RS10560	COG1201	RNA secondary structure unwinding
H0E72_RS10570	COG0346	lactoylglutathione lyase activity
H0E72_RS10575	COG1902	pentaerythritol trinitrate reductase activity
H0E72_RS10580	COG1309	transcriptional regulator
H0E72_RS10585	COG3313	Fe-S protein
H0E72_RS10590	COG4989	oxidoreductase activity
H0E72_RS10595	COG2032	superoxide dismutase activity
H0E72_RS10600	COG1289	transmembrane transporter activity
H0E72_RS10605	COG1566	PFAM secretion protein HlyD family protein
H0E72_RS10620	COG3133	Outer membrane lipoprotein
H0E72_RS10630	COG3895	Periplasmic Protein
H0E72_RS10645	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
H0E72_RS10650	COG0625	glutathione transferase activity
H0E72_RS10655	COG3104	oligopeptide transport
H0E72_RS10660	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H0E72_RS10670	COG4659	FMN binding
H0E72_RS10710	COG0673	inositol 2-dehydrogenase activity
H0E72_RS10720	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
H0E72_RS10725	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H0E72_RS10725	COG1263	PTS System
H0E72_RS10730	COG1609	Transcriptional regulator
H0E72_RS10735	COG1028	Short-chain dehydrogenase reductase Sdr
H0E72_RS10740	COG1309	transcriptional regulator
H0E72_RS10745	COG3250	beta-galactosidase activity
H0E72_RS10760	COG5339	Protein conserved in bacteria
H0E72_RS10765	COG1482	cell wall glycoprotein biosynthetic process
H0E72_RS10770	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H0E72_RS10770	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
H0E72_RS10775	COG0114	fumarate hydratase activity
H0E72_RS10785	COG2205	protein histidine kinase activity
H0E72_RS10790	COG0745	RESPONSE REGULATOR receiver
H0E72_RS10795	COG3136	membrane protein required for alginate biosynthesis
H0E72_RS10805	COG0531	amino acid
H0E72_RS10815	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
H0E72_RS10820	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
H0E72_RS10825	COG0628	permease
H0E72_RS10840	COG3591	Belongs to the peptidase S1B family
H0E72_RS10855	COG2814	Major facilitator Superfamily
H0E72_RS10860	COG0583	DNA-binding transcription factor activity
H0E72_RS10865	COG1940	carbohydrate kinase activity
H0E72_RS10870	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
H0E72_RS10880	COG3381	protein complex oligomerization
H0E72_RS10885	COG3302	dmso reductase anchor subunit
H0E72_RS10890	COG0437	4 iron, 4 sulfur cluster binding
H0E72_RS10900	COG0243	molybdopterin cofactor binding
H0E72_RS10915	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H0E72_RS10930	COG4948	Mandelate Racemase Muconate Lactonizing
H0E72_RS10935	COG1063	alcohol dehydrogenase
H0E72_RS10945	COG0582	viral genome integration into host DNA
H0E72_RS10955	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H0E72_RS10980	COG1396	sequence-specific DNA binding
H0E72_RS10995	COG1846	Transcriptional regulator
H0E72_RS11035	COG1403	HNH endonuclease
H0E72_RS11050	COG3272	Protein of unknown function (DUF1722)
H0E72_RS11055	COG2207	Transcriptional regulator
H0E72_RS11075	COG3772	lysozyme
H0E72_RS11085	COG5562	phage envelope protein
H0E72_RS11110	COG0740	serine-type endopeptidase activity
H0E72_RS11185	COG5301	cellulose 1,4-beta-cellobiosidase activity
H0E72_RS11210	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H0E72_RS11230	COG0246	Mannitol dehydrogenase
H0E72_RS11240	COG1802	Transcriptional regulator
H0E72_RS11245	COG4221	oxidoreductase activity
H0E72_RS11250	COG0339	signal peptide processing
H0E72_RS11255	COG3111	PFAM Bacterial OB fold (BOF) protein
H0E72_RS11260	COG3706	GGDEF domain
H0E72_RS11270	COG2814	Major facilitator Superfamily
H0E72_RS11275	COG0697	spore germination
H0E72_RS11280	COG2188	Transcriptional regulator
H0E72_RS11290	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H0E72_RS11295	COG1447	Phosphotransferase system cellobiose-specific component IIA
H0E72_RS11305	COG2723	6-phospho-beta-galactosidase activity
H0E72_RS11315	COG4977	sequence-specific DNA binding
H0E72_RS11320	COG1846	Transcriptional regulator
H0E72_RS11340	COG3039	Transposase
H0E72_RS11350	COG0583	DNA-binding transcription factor activity
H0E72_RS11355	COG1012	belongs to the aldehyde dehydrogenase family
H0E72_RS11360	COG2066	Belongs to the glutaminase family
H0E72_RS11370	COG2199	diguanylate cyclase activity
H0E72_RS11380	COG3781	membrane
H0E72_RS11445	COG3539	Fimbrial protein
H0E72_RS11470	COG3539	Fimbrial protein
H0E72_RS11475	COG3539	Fimbrial protein
H0E72_RS11480	COG3539	Fimbrial protein
H0E72_RS11485	COG0243	molybdopterin cofactor binding
H0E72_RS11500	COG3119	arylsulfatase activity
H0E72_RS11505	COG0641	radical SAM
H0E72_RS11515	COG4178	(ABC) transporter
H0E72_RS11520	COG4771	TonB-dependent receptor
H0E72_RS11525	COG0612	Peptidase, M16
H0E72_RS11530	COG0076	glutamate decarboxylase activity
H0E72_RS11535	COG0531	amino acid
H0E72_RS11555	COG2200	EAL domain
H0E72_RS11555	COG2202	Pas domain
H0E72_RS11555	COG2199	diguanylate cyclase activity
H0E72_RS11560	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
H0E72_RS11565	COG0747	negative chemotaxis
H0E72_RS11570	COG0601	transmembrane transport
H0E72_RS11575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H0E72_RS11580	COG0444	Belongs to the ABC transporter superfamily
H0E72_RS11585	COG4608	Belongs to the ABC transporter superfamily
H0E72_RS11590	COG1764	response to oxidative stress
H0E72_RS11610	COG1064	alcohol dehydrogenase
H0E72_RS11615	COG3093	addiction module antidote protein HigA
H0E72_RS11620	COG2864	formate dehydrogenase
H0E72_RS11625	COG0437	4 iron, 4 sulfur cluster binding
H0E72_RS11635	COG0697	spore germination
H0E72_RS11645	COG4886	Leucine-rich repeat (LRR) protein
H0E72_RS11650	COG4886	Leucine-rich repeat (LRR) protein
H0E72_RS11655	COG2223	nitrite transmembrane transporter activity
H0E72_RS11660	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
H0E72_RS11665	COG1140	nitrate reductase beta subunit
H0E72_RS11670	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
H0E72_RS11675	COG2181	nitrate reductase activity
H0E72_RS11680	COG0384	phenazine biosynthesis protein PhzF
H0E72_RS11685	COG2162	N-hydroxyarylamine O-acetyltransferase activity
H0E72_RS11690	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H0E72_RS11700	COG2015	COG2015, Alkyl sulfatase and related hydrolases
H0E72_RS11705	COG2203	Gaf domain
H0E72_RS11705	COG4251	negative regulation of phosphorylation
H0E72_RS11705	COG3706	GGDEF domain
H0E72_RS11705	COG5001	Diguanylate cyclase
H0E72_RS11710	COG0625	glutathione transferase activity
H0E72_RS11715	COG1113	amino acid transport
H0E72_RS11725	COG4772	TonB-dependent receptor
H0E72_RS11730	COG1802	Transcriptional regulator
H0E72_RS11735	COG2130	NADP-dependent
H0E72_RS11740	COG1247	-acetyltransferase
H0E72_RS11745	COG3238	Protein conserved in bacteria
H0E72_RS11770	COG1177	transmembrane transport
H0E72_RS11775	COG1176	ABC-type spermidine putrescine transport system, permease component I
H0E72_RS11780	COG3842	ATPase activity
H0E72_RS11785	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
H0E72_RS11790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H0E72_RS11795	COG1598	PFAM Uncharacterised protein family UPF0150
H0E72_RS11800	COG1724	mRNA binding
H0E72_RS11810	COG0826	peptidase U32
H0E72_RS11815	COG1396	sequence-specific DNA binding
H0E72_RS11825	COG3385	transposase activity
H0E72_RS11840	COG0500	methyltransferase
H0E72_RS11845	COG1275	C4-dicarboxylate transporter malic acid transport protein
H0E72_RS11850	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H0E72_RS11855	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H0E72_RS11860	COG2841	Protein conserved in bacteria
H0E72_RS11870	COG5383	Protein conserved in bacteria
H0E72_RS11875	COG0583	DNA-binding transcription factor activity
H0E72_RS11880	COG0840	transmembrane signaling receptor activity
H0E72_RS11895	COG3038	cytochrome b561
H0E72_RS11900	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H0E72_RS11905	COG1012	belongs to the aldehyde dehydrogenase family
H0E72_RS11910	COG1434	Gram-negative-bacterium-type cell wall biogenesis
H0E72_RS11915	COG1643	Atp-dependent helicase
H0E72_RS11925	COG0671	phosphoesterase, PA-phosphatase related
H0E72_RS11925	COG2453	phosphatase
H0E72_RS11930	COG2267	carboxylic ester hydrolase activity
H0E72_RS11935	COG4589	Belongs to the CDS family
H0E72_RS11940	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H0E72_RS11950	COG0667	Aldo Keto reductase
H0E72_RS11960	COG3784	Protein of unknown function (DUF1318)
H0E72_RS11970	COG2911	Protein conserved in bacteria
H0E72_RS11975	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H0E72_RS11980	COG3187	Heat shock protein
H0E72_RS11985	COG3042	response to heat
H0E72_RS11990	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H0E72_RS11990	COG0674	pyruvate-flavodoxin oxidoreductase activity
H0E72_RS11990	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
H0E72_RS11990	COG1013	pyruvate-flavodoxin oxidoreductase activity
H0E72_RS11995	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
H0E72_RS12000	COG0589	response to stress
H0E72_RS12010	COG0513	Belongs to the DEAD box helicase family
H0E72_RS12020	COG3706	GGDEF domain
H0E72_RS12025	COG2840	Smr protein MutS2
H0E72_RS12030	COG0583	DNA-binding transcription factor activity
H0E72_RS12035	COG1473	amidohydrolase
H0E72_RS12040	COG1473	amidohydrolase
H0E72_RS12045	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
H0E72_RS12050	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H0E72_RS12055	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H0E72_RS12060	COG0589	response to stress
H0E72_RS12065	COG3182	Iron-regulated membrane protein
H0E72_RS12070	COG0668	transmembrane transport
H0E72_RS12075	COG4166	transmembrane transport
H0E72_RS12080	COG0583	DNA-binding transcription factor activity
H0E72_RS12085	COG1073	alpha beta
H0E72_RS12095	COG0702	epimerase
H0E72_RS12100	COG2866	Carboxypeptidase
H0E72_RS12105	COG4948	Mandelate Racemase Muconate Lactonizing
H0E72_RS12110	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
H0E72_RS12115	COG3283	Transcriptional regulator of aromatic amino acids metabolism
H0E72_RS12125	COG3106	COG3106 Predicted ATPase
H0E72_RS12130	COG1609	Transcriptional regulator
H0E72_RS12140	COG3842	ATPase activity
H0E72_RS12145	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H0E72_RS12150	COG1554	hydrolase, family 65, central catalytic
H0E72_RS12155	COG0673	inositol 2-dehydrogenase activity
H0E72_RS12160	COG1082	Xylose isomerase domain protein TIM barrel
H0E72_RS12165	COG1063	alcohol dehydrogenase
H0E72_RS12170	COG0395	ABC-type sugar transport system, permease component
H0E72_RS12175	COG1175	transmembrane transport
H0E72_RS12180	COG1653	transport
H0E72_RS12185	COG0366	Alpha amylase catalytic
H0E72_RS12190	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H0E72_RS12200	COG1983	PspC domain protein
H0E72_RS12210	COG1842	Phage shock protein A
H0E72_RS12215	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
H0E72_RS12220	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H0E72_RS12225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H0E72_RS12230	COG1012	belongs to the aldehyde dehydrogenase family
H0E72_RS12235	COG1917	Cupin 2, conserved barrel domain protein
H0E72_RS12235	COG1396	sequence-specific DNA binding
H0E72_RS12240	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
H0E72_RS12245	COG0174	glutamine synthetase
H0E72_RS12255	COG0531	amino acid
H0E72_RS12265	COG4166	transmembrane transport
H0E72_RS12270	COG4168	peptide transport system, permease
H0E72_RS12275	COG4171	peptide transport system, permease
H0E72_RS12280	COG4172	Belongs to the ABC transporter superfamily
H0E72_RS12285	COG4172	Belongs to the ABC transporter superfamily
H0E72_RS12290	COG2814	Major facilitator Superfamily
H0E72_RS12300	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H0E72_RS12305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0E72_RS12315	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
H0E72_RS12320	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H0E72_RS12320	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H0E72_RS12335	COG5001	Diguanylate cyclase
H0E72_RS12345	COG1349	DNA-binding transcription factor activity
H0E72_RS12355	COG0023	Translation Initiation Factor
H0E72_RS12365	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
H0E72_RS12370	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
H0E72_RS12375	COG0671	phosphoesterase, PA-phosphatase related
H0E72_RS12385	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H0E72_RS12405	COG0583	DNA-binding transcription factor activity
H0E72_RS12410	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H0E72_RS12420	COG0616	signal peptide processing
H0E72_RS12425	COG1028	Short-chain dehydrogenase reductase Sdr
H0E72_RS12430	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
H0E72_RS12445	COG1187	pseudouridine synthase activity
H0E72_RS12450	COG4907	membrane protein (DUF2207)
H0E72_RS12455	COG0009	L-threonylcarbamoyladenylate synthase
H0E72_RS12460	COG0613	PHP domain protein
H0E72_RS12470	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H0E72_RS12475	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H0E72_RS12475	COG0512	Glutamine amidotransferase of anthranilate synthase
H0E72_RS12480	COG0134	indole-3-glycerol-phosphate synthase activity
H0E72_RS12480	COG0135	phosphoribosylanthranilate isomerase activity
H0E72_RS12495	COG3729	General stress protein
H0E72_RS12500	COG3685	Protein conserved in bacteria
H0E72_RS12525	COG0500	methyltransferase
H0E72_RS12530	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
H0E72_RS12535	COG5301	cellulose 1,4-beta-cellobiosidase activity
H0E72_RS12640	COG4220	transposase activity
H0E72_RS12670	COG3772	lysozyme
H0E72_RS12710	COG0484	heat shock protein binding
H0E72_RS12715	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
H0E72_RS12720	COG1403	HNH endonuclease
H0E72_RS12795	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H0E72_RS12805	COG0582	viral genome integration into host DNA
H0E72_RS12810	COG3047	cAMP biosynthetic process
H0E72_RS12830	COG1607	acyl-coa hydrolase
H0E72_RS12840	COG2350	Protein conserved in bacteria
H0E72_RS12875	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H0E72_RS12895	COG4608	Belongs to the ABC transporter superfamily
H0E72_RS12900	COG0444	Belongs to the ABC transporter superfamily
H0E72_RS12905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H0E72_RS12910	COG0601	transmembrane transport
H0E72_RS12915	COG4166	transmembrane transport
H0E72_RS12925	COG2095	MarC family integral membrane protein
H0E72_RS12930	COG1454	alcohol dehydrogenase
H0E72_RS12930	COG1012	belongs to the aldehyde dehydrogenase family
H0E72_RS12935	COG1435	thymidine kinase activity
H0E72_RS12945	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H0E72_RS12950	COG0745	RESPONSE REGULATOR receiver
H0E72_RS12955	COG1752	Esterase of the alpha-beta hydrolase superfamily
H0E72_RS12965	COG0788	formyltetrahydrofolate deformylase activity
H0E72_RS12985	COG2181	nitrate reductase activity
H0E72_RS12990	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
H0E72_RS12995	COG1140	nitrate reductase beta subunit
H0E72_RS13000	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
H0E72_RS13005	COG2223	nitrite transmembrane transporter activity
H0E72_RS13010	COG3850	Histidine kinase
H0E72_RS13015	COG2197	response regulator
H0E72_RS13020	COG4932	domain protein
H0E72_RS13025	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
H0E72_RS13030	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
H0E72_RS13035	COG4572	Cation transport regulator
H0E72_RS13040	COG0387	Pfam Sodium calcium exchanger
H0E72_RS13060	COG2912	Transglutaminase-like superfamily
H0E72_RS13065	COG3094	Invasion gene expression up-regulator, SirB
H0E72_RS13070	COG2890	protein-(glutamine-N5) methyltransferase activity
H0E72_RS13095	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H0E72_RS13100	COG0659	secondary active sulfate transmembrane transporter activity
H0E72_RS13115	COG0012	GTP binding
H0E72_RS13125	COG3284	Transcriptional regulator
H0E72_RS13130	COG2376	Dihydroxyacetone kinase
H0E72_RS13135	COG1461	Dihydroxyacetone kinase
H0E72_RS13140	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
H0E72_RS13140	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H0E72_RS13140	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H0E72_RS13160	COG1120	ATPase activity
H0E72_RS13165	COG0500	methyltransferase
H0E72_RS13170	COG0157	Belongs to the NadC ModD family
H0E72_RS13185	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
H0E72_RS13195	COG1619	proteins homologs of microcin C7 resistance protein MccF
H0E72_RS13215	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H0E72_RS13225	COG2719	SpoVR family
H0E72_RS13240	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
H0E72_RS13245	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H0E72_RS13250	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H0E72_RS13265	COG0179	Fumarylacetoacetate (FAA) hydrolase
H0E72_RS13290	COG2894	cell division
H0E72_RS13335	COG2200	EAL domain
H0E72_RS13360	COG2200	EAL domain
H0E72_RS13365	COG0789	Transcriptional regulator
H0E72_RS13370	COG5562	phage envelope protein
H0E72_RS13390	COG0538	isocitrate dehydrogenase activity
H0E72_RS13395	COG1187	pseudouridine synthase activity
H0E72_RS13415	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H0E72_RS13425	COG2205	protein histidine kinase activity
H0E72_RS13430	COG2850	peptidyl-arginine hydroxylation
H0E72_RS13440	COG3842	ATPase activity
H0E72_RS13450	COG1177	transmembrane transport
H0E72_RS13455	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
H0E72_RS13465	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
H0E72_RS13470	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H0E72_RS13480	COG4591	ABC-type transport system involved in lipoprotein release permease component
H0E72_RS13485	COG1136	(ABC) transporter
H0E72_RS13490	COG4591	ABC-type transport system involved in lipoprotein release permease component
H0E72_RS13495	COG4763	Acyl-transferase
H0E72_RS13500	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H0E72_RS13505	COG1376	ErfK ybiS ycfS ynhG family protein
H0E72_RS13505	COG1388	LysM domain
H0E72_RS13515	COG1309	transcriptional regulator
H0E72_RS13520	COG3134	Outer membrane lipoprotein
H0E72_RS13525	COG1252	NADH dehydrogenase
H0E72_RS13545	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
H0E72_RS13550	COG5633	Lipoprotein
H0E72_RS13555	COG0537	adenosine 5'-monophosphoramidase activity
H0E72_RS13560	COG4773	Receptor
H0E72_RS13565	COG1263	PTS System
H0E72_RS13565	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H0E72_RS13570	COG0084	hydrolase, TatD family'
H0E72_RS13575	COG0470	DNA polymerase III
H0E72_RS13585	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H0E72_RS13590	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H0E72_RS13595	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H0E72_RS13605	COG1028	Short-chain dehydrogenase reductase Sdr
H0E72_RS13610	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H0E72_RS13630	COG1399	metal-binding, possibly nucleic acid-binding protein
H0E72_RS13635	COG0424	maF-like protein
H0E72_RS13640	COG0564	pseudouridine synthase activity
H0E72_RS13645	COG1530	ribonuclease E activity
H0E72_RS13660	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H0E72_RS13665	COG1256	bacterial-type flagellum assembly
H0E72_RS13670	COG1705	Flagellar rod assembly protein muramidase FlgJ
H0E72_RS13670	COG3951	Flagellar rod assembly protein muramidase FlgJ
H0E72_RS13675	COG1706	bacterial-type flagellum-dependent cell motility
H0E72_RS13685	COG4786	Flagellar basal body rod
H0E72_RS13690	COG4787	bacterial-type flagellum-dependent cell motility
H0E72_RS13695	COG1749	Flagellar hook protein flgE
H0E72_RS13700	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
H0E72_RS13705	COG1558	bacterial-type flagellum-dependent cell motility
H0E72_RS13710	COG1815	bacterial-type flagellum-dependent cell motility
H0E72_RS13715	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
H0E72_RS13720	COG2747	anti-sigma28 factor FlgM
H0E72_RS13725	COG3418	PFAM FlgN family protein
H0E72_RS13730	COG0728	peptidoglycan biosynthetic process
H0E72_RS13735	COG0673	inositol 2-dehydrogenase activity
H0E72_RS13745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H0E72_RS13755	COG2999	glutathione oxidoreductase activity
H0E72_RS13790	COG3038	cytochrome b561
H0E72_RS13795	COG2353	YceI-like domain
H0E72_RS13805	COG1560	Kdo2-lipid A biosynthetic process
H0E72_RS13820	COG5645	(Lipo)protein
H0E72_RS13825	COG2943	transferase activity, transferring hexosyl groups
H0E72_RS13840	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H0E72_RS13845	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
H0E72_RS13870	COG2197	response regulator
H0E72_RS13885	COG1462	curli production assembly transport component CsgG
H0E72_RS13895	COG3381	protein complex oligomerization
H0E72_RS13920	COG1702	phosphate starvation-inducible protein PhoH
H0E72_RS13940	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H0E72_RS13950	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H0E72_RS13950	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H0E72_RS13950	COG0506	proline dehydrogenase activity
H0E72_RS13955	COG1309	transcriptional regulator
H0E72_RS13990	COG2233	PERMEase
H0E72_RS13995	COG3729	General stress protein
H0E72_RS14035	COG0243	molybdopterin cofactor binding
H0E72_RS14040	COG3005	denitrification pathway
H0E72_RS14045	COG0745	RESPONSE REGULATOR receiver
H0E72_RS14050	COG1879	ABC-type sugar transport system periplasmic component
H0E72_RS14055	COG0784	Response regulator, receiver
H0E72_RS14055	COG2198	Histidine kinase
H0E72_RS14055	COG2205	protein histidine kinase activity
H0E72_RS14060	COG0348	domain, Protein
H0E72_RS14080	COG1278	Cold shock
H0E72_RS14085	COG1278	Cold shock
H0E72_RS14100	COG1294	oxidase, subunit
H0E72_RS14105	COG1271	oxidase subunit
H0E72_RS14110	COG1773	rubredoxin
H0E72_RS14115	COG1999	signal sequence binding
H0E72_RS14120	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
H0E72_RS14125	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
H0E72_RS14130	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
H0E72_RS14135	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
H0E72_RS14145	COG0670	Belongs to the BI1 family
H0E72_RS14150	COG2920	part of a sulfur-relay system
H0E72_RS14155	COG1254	Belongs to the acylphosphatase family
H0E72_RS14170	COG1832	CoA-binding protein
H0E72_RS14185	COG0210	DNA helicase
H0E72_RS14190	COG3304	Inner membrane component domain
H0E72_RS14195	COG1289	transmembrane transporter activity
H0E72_RS14200	COG3070	regulator of competence-specific genes
H0E72_RS14220	COG1067	ATP-dependent peptidase activity
H0E72_RS14230	COG3130	regulation of translation
H0E72_RS14235	COG3009	Protein conserved in bacteria
H0E72_RS14240	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H0E72_RS14240	COG3008	intermembrane lipid transfer
H0E72_RS14245	COG2995	paraquat-inducible protein a
H0E72_RS14250	COG0488	(ABC) transporter
H0E72_RS14260	COG0633	Ferredoxin
H0E72_RS14260	COG3217	Mosc domain protein beta barrel domain protein
H0E72_RS14275	COG3121	Chaperone
H0E72_RS14280	COG3539	Fimbrial protein
H0E72_RS14285	COG3539	Fimbrial protein
H0E72_RS14290	COG3539	Fimbrial protein
H0E72_RS14295	COG3188	usher protein
H0E72_RS14300	COG3121	Chaperone
H0E72_RS14305	COG3539	Fimbrial protein
H0E72_RS14310	COG0431	NADPH-dependent FMN reductase
H0E72_RS14315	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H0E72_RS14325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H0E72_RS14330	COG1116	anion transmembrane transporter activity
H0E72_RS14335	COG0308	aminopeptidase N
H0E72_RS14350	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
H0E72_RS14355	COG1448	Aminotransferase
H0E72_RS14360	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H0E72_RS14365	COG3108	Peptidase M15
H0E72_RS14370	COG2989	Protein conserved in bacteria
H0E72_RS14380	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
H0E72_RS14390	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H0E72_RS14395	COG1434	Gram-negative-bacterium-type cell wall biogenesis
H0E72_RS14400	COG3173	Aminoglycoside phosphotransferase
H0E72_RS14415	COG3214	Protein conserved in bacteria
H0E72_RS14425	COG1132	(ABC) transporter
H0E72_RS14440	COG0539	negative regulation of cytoplasmic translation
H0E72_RS14450	COG0501	Belongs to the peptidase M48B family
H0E72_RS14455	COG3385	transposase activity
H0E72_RS14470	COG2323	membrane
H0E72_RS14475	COG1944	ATP diphosphatase activity
H0E72_RS14480	COG2116	formate transmembrane transporter activity
H0E72_RS14485	COG1882	Formate acetyltransferase
H0E72_RS14490	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H0E72_RS14500	COG0531	amino acid
H0E72_RS14510	COG1335	isochorismatase
H0E72_RS14520	COG0437	4 iron, 4 sulfur cluster binding
H0E72_RS14525	COG0243	molybdopterin cofactor binding
H0E72_RS14535	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H0E72_RS14545	COG1674	ftsk spoiiie
H0E72_RS14545	COG1178	ABC-type Fe3 transport system permease component
H0E72_RS14550	COG1522	sequence-specific DNA binding
H0E72_RS14555	COG0492	ferredoxin-NADP+ reductase activity
H0E72_RS14560	COG4988	ABC transporter
H0E72_RS14565	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
H0E72_RS14585	COG0542	response to heat
H0E72_RS14595	COG1278	Cold shock
H0E72_RS14605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0E72_RS14610	COG2990	Protein conserved in bacteria
H0E72_RS14615	COG3593	DNA synthesis involved in DNA repair
H0E72_RS14620	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H0E72_RS14630	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H0E72_RS14640	COG1346	cytolysis
H0E72_RS14650	COG2949	membrane
H0E72_RS14660	COG0493	'glutamate synthase
H0E72_RS14665	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
H0E72_RS14665	COG0167	dihydroorotate dehydrogenase activity
H0E72_RS14670	COG4211	Belongs to the binding-protein-dependent transport system permease family
H0E72_RS14675	COG1129	ABC transporter
H0E72_RS14680	COG1879	ABC-type sugar transport system periplasmic component
H0E72_RS14685	COG1609	Transcriptional regulator
H0E72_RS14690	COG2311	Membrane
H0E72_RS14705	COG4771	TonB-dependent receptor
H0E72_RS14710	COG0833	amino acid
H0E72_RS14715	COG0583	DNA-binding transcription factor activity
H0E72_RS14720	COG2855	membrane
H0E72_RS14730	COG1522	sequence-specific DNA binding
H0E72_RS14730	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H0E72_RS14735	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H0E72_RS14745	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H0E72_RS14750	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H0E72_RS14755	COG2313	pseudouridylate synthase activity
H0E72_RS14760	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H0E72_RS14765	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H0E72_RS14765	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
H0E72_RS14765	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H0E72_RS14770	COG1105	Belongs to the carbohydrate kinase PfkB family
H0E72_RS14775	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H0E72_RS14775	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H0E72_RS14780	COG2814	Major facilitator Superfamily
H0E72_RS14795	COG0246	Mannitol dehydrogenase
H0E72_RS14800	COG0523	cobalamin synthesis protein
H0E72_RS14805	COG0671	phosphoesterase, PA-phosphatase related
H0E72_RS14810	COG0791	NLP P60 protein
H0E72_RS14815	COG2200	EAL domain
H0E72_RS14820	COG4166	transmembrane transport
H0E72_RS14825	COG4174	ABC transporter (Permease)
H0E72_RS14830	COG4239	(ABC) transporter, permease
H0E72_RS14835	COG4172	Belongs to the ABC transporter superfamily
H0E72_RS14845	COG2814	Major facilitator Superfamily
H0E72_RS14850	COG1187	pseudouridine synthase activity
H0E72_RS14855	COG1061	Type III restriction enzyme res subunit
H0E72_RS14875	COG3083	sulfuric ester hydrolase activity
H0E72_RS14885	COG3468	outer membrane autotransporter barrel domain protein
H0E72_RS14890	COG2197	response regulator
H0E72_RS14895	COG4235	cytochrome complex assembly
H0E72_RS14895	COG3088	subunit of a heme lyase
H0E72_RS14900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H0E72_RS14905	COG1138	Cytochrome C-type biogenesis protein
H0E72_RS14915	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H0E72_RS14920	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H0E72_RS14925	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H0E72_RS14930	COG4133	protoheme IX ABC transporter activity
H0E72_RS14935	COG3005	denitrification pathway
H0E72_RS14940	COG3043	anaerobic respiration
H0E72_RS14945	COG0348	domain, Protein
H0E72_RS14950	COG0437	4 iron, 4 sulfur cluster binding
H0E72_RS14960	COG3062	negative regulation of establishment of protein localization
H0E72_RS14965	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H0E72_RS14965	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
H0E72_RS14985	COG4615	Cyclic peptide transporter
H0E72_RS14990	COG3145	DNA-N1-methyladenine dioxygenase activity
H0E72_RS14995	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H0E72_RS14995	COG2169	Transcriptional regulator
H0E72_RS15000	COG1477	protein flavinylation
H0E72_RS15005	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
H0E72_RS15010	COG2198	Histidine kinase
H0E72_RS15010	COG0642	Histidine kinase
H0E72_RS15015	COG2197	response regulator
H0E72_RS15020	COG2205	protein histidine kinase activity
H0E72_RS15020	COG0784	Response regulator, receiver
H0E72_RS15025	COG3852	Histidine kinase
H0E72_RS15030	COG2204	response regulator
H0E72_RS15035	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H0E72_RS15040	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H0E72_RS15045	COG2031	fatty acid transporter
H0E72_RS15050	COG0183	Belongs to the thiolase family
H0E72_RS15055	COG4676	Protein conserved in bacteria
H0E72_RS15060	COG5445	Predicted secreted protein (DUF2300)
H0E72_RS15065	COG2373	Large extracellular alpha-helical protein
H0E72_RS15070	COG3234	Protein of unknown function (DUF1175)
H0E72_RS15075	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
H0E72_RS15080	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H0E72_RS15085	COG4948	Mandelate Racemase Muconate Lactonizing
H0E72_RS15095	COG1802	Transcriptional regulator
H0E72_RS15105	COG3468	outer membrane autotransporter barrel domain protein
H0E72_RS15110	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H0E72_RS15115	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H0E72_RS15120	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H0E72_RS15125	COG3642	lipopolysaccharide core region biosynthetic process
H0E72_RS15130	COG2814	Major facilitator Superfamily
H0E72_RS15135	COG0583	DNA-binding transcription factor activity
H0E72_RS15140	COG0584	glycerophosphoryl diester phosphodiesterase
H0E72_RS15145	COG2271	Major facilitator Superfamily
H0E72_RS15150	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
H0E72_RS15160	COG0247	lactate metabolic process
H0E72_RS15165	COG5464	transposase or invertase
H0E72_RS15180	COG2271	Major facilitator Superfamily
H0E72_RS15190	COG1414	Transcriptional regulator
H0E72_RS15255	COG0318	PFAM AMP-dependent synthetase and ligase
H0E72_RS15265	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
H0E72_RS15280	COG1169	isochorismate synthase
H0E72_RS15285	COG4575	ribosome binding
H0E72_RS15290	COG2153	protein acetylation
H0E72_RS15300	COG5160	protein modification by small protein removal
H0E72_RS15305	COG2304	oxidoreductase activity
H0E72_RS15310	COG2234	aminopeptidase activity
H0E72_RS15325	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H0E72_RS15330	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H0E72_RS15340	COG0839	Belongs to the complex I subunit 6 family
H0E72_RS15355	COG1034	ATP synthesis coupled electron transport
H0E72_RS15360	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
H0E72_RS15365	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
H0E72_RS15385	COG0583	DNA-binding transcription factor activity
H0E72_RS15390	COG0436	Aminotransferase
H0E72_RS15400	COG0490	domain, Protein
H0E72_RS15400	COG0471	metal ion transport
H0E72_RS15405	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H0E72_RS15420	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H0E72_RS15425	COG0857	belongs to the CobB CobQ family
H0E72_RS15425	COG0280	phosphate acetyltransferase
H0E72_RS15430	COG1288	antiporter activity
H0E72_RS15435	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
H0E72_RS15440	COG0622	Phosphoesterase
H0E72_RS15445	COG0625	glutathione transferase activity
H0E72_RS15450	COG0625	glutathione transferase activity
H0E72_RS15455	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
H0E72_RS15460	COG1090	epimerase
H0E72_RS15465	COG5464	transposase or invertase
H0E72_RS15470	COG4598	ABC transporter
H0E72_RS15475	COG4160	amino acid transport
H0E72_RS15480	COG4215	(ABC) transporter
H0E72_RS15485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H0E72_RS15490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H0E72_RS15495	COG0163	prenyltransferase activity
H0E72_RS15500	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
H0E72_RS15505	COG1286	toxin biosynthetic process
H0E72_RS15510	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
H0E72_RS15515	COG0285	dihydrofolate synthase activity
H0E72_RS15525	COG0586	Pfam SNARE associated Golgi protein
H0E72_RS15535	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H0E72_RS15550	COG2814	Major facilitator Superfamily
H0E72_RS15555	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H0E72_RS15570	COG3101	peptidyl-lysine hydroxylation
H0E72_RS15575	COG0730	response to heat
H0E72_RS15590	COG2890	protein-(glutamine-N5) methyltransferase activity
H0E72_RS15615	COG3539	Fimbrial protein
H0E72_RS15620	COG3539	Fimbrial protein
H0E72_RS15625	COG3539	Fimbrial protein
H0E72_RS15630	COG3121	Chaperone
H0E72_RS15635	COG3188	usher protein
H0E72_RS15640	COG3539	Fimbrial protein
H0E72_RS15645	COG2062	phosphohistidine phosphatase, SixA
H0E72_RS15660	COG3691	Protein conserved in bacteria
H0E72_RS15665	COG2067	long-chain fatty acid transport protein
H0E72_RS15675	COG2853	Lipoprotein
H0E72_RS15680	COG2116	formate transmembrane transporter activity
H0E72_RS15705	COG0582	viral genome integration into host DNA
H0E72_RS15710	COG0582	viral genome integration into host DNA
H0E72_RS15715	COG0583	DNA-binding transcription factor activity
H0E72_RS15720	COG2610	gluconate transmembrane transporter activity
H0E72_RS15730	COG0477	Major facilitator Superfamily
H0E72_RS15735	COG1566	PFAM secretion protein HlyD family protein
H0E72_RS15740	COG2197	response regulator
H0E72_RS15745	COG2198	Histidine kinase
H0E72_RS15745	COG2205	protein histidine kinase activity
H0E72_RS15745	COG0784	Response regulator, receiver
H0E72_RS15745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H0E72_RS15750	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H0E72_RS15755	COG0679	Auxin Efflux Carrier
H0E72_RS15760	COG0028	Belongs to the TPP enzyme family
H0E72_RS15785	COG1560	Kdo2-lipid A biosynthetic process
H0E72_RS15795	COG0436	Aminotransferase
H0E72_RS15800	COG3275	phosphorelay sensor kinase activity
H0E72_RS15805	COG3279	Response regulator of the LytR AlgR family
H0E72_RS15810	COG2207	Transcriptional regulator
H0E72_RS15815	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H0E72_RS15815	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H0E72_RS15815	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H0E72_RS15820	COG1363	Peptidase, m42
H0E72_RS15825	COG0006	proline dipeptidase activity
H0E72_RS15830	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H0E72_RS15835	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H0E72_RS15860	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H0E72_RS15865	COG2200	EAL domain
H0E72_RS15865	COG2199	diguanylate cyclase activity
H0E72_RS15880	COG3415	Transposase
H0E72_RS15885	COG3415	Transposase
H0E72_RS15925	COG0583	DNA-binding transcription factor activity
H0E72_RS15935	COG2211	Major facilitator Superfamily
H0E72_RS15940	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
H0E72_RS15950	COG0583	DNA-binding transcription factor activity
H0E72_RS15955	COG0385	Bile acid
H0E72_RS15960	COG3530	Putative quorum-sensing-regulated virulence factor
H0E72_RS15980	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H0E72_RS15985	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H0E72_RS15990	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H0E72_RS15995	COG2190	(PTS) system
H0E72_RS16000	COG3385	transposase activity
H0E72_RS16015	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H0E72_RS16020	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
H0E72_RS16025	COG4208	sulfate ABC transporter
H0E72_RS16030	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
H0E72_RS16035	COG4150	thiosulfate binding
H0E72_RS16040	COG1028	Short-chain dehydrogenase reductase Sdr
H0E72_RS16055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H0E72_RS16055	COG1263	PTS System
H0E72_RS16060	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H0E72_RS16065	COG2837	iron assimilation
H0E72_RS16085	COG0860	N-Acetylmuramoyl-L-alanine amidase
H0E72_RS16095	COG2207	Transcriptional regulator
H0E72_RS16100	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
H0E72_RS16105	COG4816	utilization protein
H0E72_RS16115	COG4303	Ethanolamine ammonia lyase large subunit
H0E72_RS16120	COG4819	ethanolamine utilization protein
H0E72_RS16125	COG3192	ethanolamine utilization protein
H0E72_RS16130	COG1454	alcohol dehydrogenase
H0E72_RS16135	COG4820	ethanolamine utilization protein (EutJ)
H0E72_RS16140	COG1012	belongs to the aldehyde dehydrogenase family
H0E72_RS16145	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
H0E72_RS16150	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
H0E72_RS16155	COG0280	phosphate acetyltransferase
H0E72_RS16160	COG4812	Cobalamin adenosyltransferase
H0E72_RS16165	COG4766	ethanolamine catabolic process
H0E72_RS16170	COG4917	ethanolamine utilization protein
H0E72_RS16175	COG4810	utilization protein
H0E72_RS16180	COG0280	phosphate acetyltransferase
H0E72_RS16180	COG0281	malic enzyme
H0E72_RS16185	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H0E72_RS16190	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H0E72_RS16195	COG5342	invasion associated locus B
H0E72_RS16205	COG0493	'glutamate synthase
H0E72_RS16205	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H0E72_RS16210	COG3850	Histidine kinase
H0E72_RS16215	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H0E72_RS16225	COG1393	Belongs to the ArsC family
H0E72_RS16240	COG0400	carboxylic ester hydrolase activity
H0E72_RS16250	COG2321	neutral zinc metallopeptidase
H0E72_RS16260	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
H0E72_RS16270	COG2716	regulation of RNA biosynthetic process
H0E72_RS16275	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H0E72_RS16280	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H0E72_RS16285	COG0651	ATP synthesis coupled electron transport
H0E72_RS16290	COG0650	Formate hydrogenlyase subunit 4
H0E72_RS16295	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H0E72_RS16300	COG4237	Hydrogenase 4 membrane
H0E72_RS16305	COG0651	ATP synthesis coupled electron transport
H0E72_RS16310	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
H0E72_RS16310	COG3261	NADH dehydrogenase
H0E72_RS16315	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H0E72_RS16320	COG3260	NADH ubiquinone oxidoreductase 20
H0E72_RS16330	COG3604	Transcriptional regulator
H0E72_RS16335	COG2116	formate transmembrane transporter activity
H0E72_RS16340	COG0628	permease
H0E72_RS16345	COG4783	chaperone-mediated protein folding
H0E72_RS16350	COG1393	Belongs to the ArsC family
H0E72_RS16360	COG2233	PERMEase
H0E72_RS16375	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H0E72_RS16380	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
H0E72_RS16385	COG0248	Ppx GppA phosphatase
H0E72_RS16390	COG2200	EAL domain
H0E72_RS16405	COG3133	Outer membrane lipoprotein
H0E72_RS16420	COG0517	IMP dehydrogenase activity
H0E72_RS16420	COG0516	GMP reductase activity
H0E72_RS16445	COG1645	bacterial-type flagellum-dependent swarming motility
H0E72_RS16460	COG2976	Protein conserved in bacteria
H0E72_RS16490	COG4953	penicillin-binding protein 1C
H0E72_RS16495	COG2373	Large extracellular alpha-helical protein
H0E72_RS16500	COG2897	thiosulfate sulfurtransferase activity
H0E72_RS16515	COG2975	iron-sulfur cluster assembly
H0E72_RS16520	COG0633	Ferredoxin
H0E72_RS16540	COG0822	iron-sulfur transferase activity
H0E72_RS16560	COG0483	inositol monophosphate 1-phosphatase activity
H0E72_RS16565	COG1073	alpha beta
H0E72_RS16570	COG3711	transcriptional antiterminator
H0E72_RS16575	COG2814	Major facilitator Superfamily
H0E72_RS16580	COG0583	DNA-binding transcription factor activity
H0E72_RS16585	COG4638	Rieske (2fe-2S)
H0E72_RS16610	COG2259	Doxx family
H0E72_RS16615	COG2017	converts alpha-aldose to the beta-anomer
H0E72_RS16620	COG1063	alcohol dehydrogenase
H0E72_RS16625	COG1172	Belongs to the binding-protein-dependent transport system permease family
H0E72_RS16630	COG1129	ABC transporter
H0E72_RS16635	COG1879	ABC-type sugar transport system periplasmic component
H0E72_RS16640	COG0457	Tetratricopeptide repeat
H0E72_RS16645	COG1940	carbohydrate kinase activity
H0E72_RS16655	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H0E72_RS16655	COG1017	nitric oxide dioxygenase activity
H0E72_RS16660	COG0347	Belongs to the P(II) protein family
H0E72_RS16665	COG2204	response regulator
H0E72_RS16670	COG3170	Tfp pilus assembly protein FimV
H0E72_RS16675	COG2205	protein histidine kinase activity
H0E72_RS16680	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H0E72_RS16680	COG0047	phosphoribosylformylglycinamidine synthase activity
H0E72_RS16695	COG0560	Phosphoserine phosphatase
H0E72_RS16700	COG1737	Transcriptional regulator
H0E72_RS16705	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H0E72_RS16720	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
H0E72_RS16740	COG0681	Belongs to the peptidase S26 family
H0E72_RS16750	COG3086	response to oxidative stress
H0E72_RS16755	COG3026	antisigma factor binding
H0E72_RS16760	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
H0E72_RS16765	COG1595	DNA-templated transcription, initiation
H0E72_RS16775	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
H0E72_RS16785	COG0513	Belongs to the DEAD box helicase family
H0E72_RS16790	COG0583	DNA-binding transcription factor activity
H0E72_RS16810	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H0E72_RS16815	COG3118	belongs to the thioredoxin family
H0E72_RS16825	COG0045	succinate-CoA ligase (ADP-forming) activity
H0E72_RS16825	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H0E72_RS16825	COG1042	CoA-binding domain protein
H0E72_RS16830	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H0E72_RS16835	COG5544	Lipoprotein
H0E72_RS16840	COG0477	Major facilitator Superfamily
H0E72_RS16865	COG0542	response to heat
H0E72_RS16875	COG0564	pseudouridine synthase activity
H0E72_RS16880	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H0E72_RS16885	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
H0E72_RS16895	COG0077	Prephenate dehydratase
H0E72_RS16895	COG1605	Chorismate mutase
H0E72_RS16900	COG1605	Chorismate mutase
H0E72_RS16900	COG0287	Prephenate dehydrogenase
H0E72_RS16905	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H0E72_RS16920	COG2199	diguanylate cyclase activity
H0E72_RS16925	COG2885	chlorophyll binding
H0E72_RS16950	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H0E72_RS16955	COG4137	Cytochrome C assembly protein
H0E72_RS16960	COG4536	flavin adenine dinucleotide binding
H0E72_RS16980	COG0497	DNA recombination
H0E72_RS16985	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H0E72_RS16995	COG2867	negative regulation of translational initiation
H0E72_RS17010	COG3468	outer membrane autotransporter barrel domain protein
H0E72_RS17045	COG0579	oxidoreductase
H0E72_RS17050	COG1012	belongs to the aldehyde dehydrogenase family
H0E72_RS17055	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H0E72_RS17060	COG1113	amino acid transport
H0E72_RS17065	COG1802	Transcriptional regulator
H0E72_RS17070	COG1652	LysM domain
H0E72_RS17075	COG0401	homolog of Blt101
H0E72_RS17080	COG0640	Transcriptional regulator
H0E72_RS17085	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H0E72_RS17090	COG2916	Histone family protein nucleoid-structuring protein H-NS
H0E72_RS17105	COG4575	ribosome binding
H0E72_RS17115	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H0E72_RS17120	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H0E72_RS17130	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H0E72_RS17135	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H0E72_RS17140	COG4175	Glycine betaine
H0E72_RS17145	COG4176	ABC-type proline glycine betaine transport system permease component
H0E72_RS17150	COG2113	Glycine betaine
H0E72_RS17155	COG2814	Major facilitator Superfamily
H0E72_RS17160	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H0E72_RS17170	COG1846	Transcriptional regulator
H0E72_RS17175	COG1566	PFAM secretion protein HlyD family protein
H0E72_RS17180	COG2814	Major facilitator Superfamily
H0E72_RS17195	COG1238	metal cluster binding
H0E72_RS17200	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H0E72_RS17230	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
H0E72_RS17250	COG1546	Belongs to the CinA family
H0E72_RS17255	COG2951	lytic endotransglycosylase activity
H0E72_RS17260	COG3730	PTS system glucitol sorbitol-specific
H0E72_RS17265	COG3732	PTS system glucitol sorbitol-specific
H0E72_RS17275	COG1028	Short-chain dehydrogenase reductase Sdr
H0E72_RS17280	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
H0E72_RS17285	COG1349	DNA-binding transcription factor activity
H0E72_RS17290	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H0E72_RS17290	COG0517	IMP dehydrogenase activity
H0E72_RS17310	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
H0E72_RS17315	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H0E72_RS17320	COG1609	Transcriptional regulator
H0E72_RS17325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H0E72_RS17325	COG1263	PTS System
H0E72_RS17330	COG2723	6-phospho-beta-galactosidase activity
H0E72_RS17340	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
H0E72_RS17350	COG3260	NADH ubiquinone oxidoreductase 20
H0E72_RS17355	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H0E72_RS17360	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
H0E72_RS17360	COG3261	NADH dehydrogenase
H0E72_RS17365	COG0650	Formate hydrogenlyase subunit 4
H0E72_RS17370	COG0651	ATP synthesis coupled electron transport
H0E72_RS17375	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H0E72_RS17385	COG0375	protein maturation
H0E72_RS17390	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
H0E72_RS17395	COG0298	carbon dioxide binding
H0E72_RS17400	COG0409	Hydrogenase expression formation protein
H0E72_RS17405	COG0309	Hydrogenase expression formation protein (HypE)
H0E72_RS17410	COG3604	Transcriptional regulator
H0E72_RS17435	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H0E72_RS17445	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
H0E72_RS17450	COG0163	prenyltransferase activity
H0E72_RS17460	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H0E72_RS17465	COG4942	peptidase
H0E72_RS17465	COG1388	LysM domain
H0E72_RS17520	COG2234	aminopeptidase activity
H0E72_RS17525	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H0E72_RS17530	COG1518	maintenance of DNA repeat elements
H0E72_RS17545	COG1857	crispr-associated protein
H0E72_RS17560	COG1203	CRISPR-associated helicase, Cas3
H0E72_RS17585	COG0720	synthase
H0E72_RS17590	COG0644	oxidoreductase
H0E72_RS17595	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
H0E72_RS17600	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
H0E72_RS17605	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
H0E72_RS17610	COG2086	electron transfer activity
H0E72_RS17615	COG0477	Major facilitator Superfamily
H0E72_RS17620	COG0277	FAD linked oxidase domain protein
H0E72_RS17625	COG1028	Short-chain dehydrogenase reductase Sdr
H0E72_RS17630	COG2223	nitrite transmembrane transporter activity
H0E72_RS17635	COG1070	Carbohydrate kinase
H0E72_RS17665	COG0602	queuosine metabolic process
H0E72_RS17675	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
H0E72_RS17685	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
H0E72_RS17690	COG3385	transposase activity
H0E72_RS17705	COG3956	TIGRFAM MazG family protein
H0E72_RS17710	COG2337	Toxic component of a toxin-antitoxin (TA) module
H0E72_RS17715	COG2336	PFAM SpoVT AbrB
H0E72_RS17720	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H0E72_RS17730	COG4999	Histidine kinase
H0E72_RS17730	COG2205	protein histidine kinase activity
H0E72_RS17730	COG3437	response regulator, receiver
H0E72_RS17730	COG3850	Histidine kinase
H0E72_RS17735	COG4948	Mandelate Racemase Muconate Lactonizing
H0E72_RS17740	COG4948	Mandelate Racemase Muconate Lactonizing
H0E72_RS17745	COG2271	Major facilitator Superfamily
H0E72_RS17750	COG0716	FMN binding
H0E72_RS17755	COG0564	pseudouridine synthase activity
H0E72_RS17760	COG3098	single-species biofilm formation
H0E72_RS17775	COG1611	Belongs to the LOG family
H0E72_RS17780	COG0814	amino acid
H0E72_RS17785	COG1760	l-serine dehydratase
H0E72_RS17795	COG1454	alcohol dehydrogenase
H0E72_RS17800	COG0235	Class ii aldolase
H0E72_RS17805	COG0738	Major facilitator superfamily
H0E72_RS17815	COG1070	Carbohydrate kinase
H0E72_RS17825	COG1349	DNA-binding transcription factor activity
H0E72_RS17835	COG2363	Small membrane protein
H0E72_RS17840	COG0583	DNA-binding transcription factor activity
H0E72_RS17850	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H0E72_RS17855	COG2166	iron-sulfur cluster assembly
H0E72_RS17860	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H0E72_RS17865	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
H0E72_RS17895	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
H0E72_RS17900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H0E72_RS17900	COG1263	PTS System
H0E72_RS17905	COG3711	transcriptional antiterminator
H0E72_RS17910	COG0860	N-Acetylmuramoyl-L-alanine amidase
H0E72_RS17915	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
H0E72_RS17915	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
H0E72_RS17920	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H0E72_RS17925	COG1074	ATP-dependent DNA helicase activity
H0E72_RS17935	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
H0E72_RS17940	COG4967	type IV pilus modification protein PilV
H0E72_RS17950	COG4795	General secretion pathway protein
H0E72_RS17955	COG2165	general secretion pathway protein
H0E72_RS17970	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
H0E72_RS17985	COG0861	Integral membrane protein TerC family
H0E72_RS17995	COG0667	Aldo Keto reductase
H0E72_RS18010	COG1609	Transcriptional regulator
H0E72_RS18020	COG0583	DNA-binding transcription factor activity
H0E72_RS18025	COG1794	racemase activity, acting on amino acids and derivatives
H0E72_RS18030	COG2814	Major facilitator Superfamily
H0E72_RS18035	COG1028	Short-chain dehydrogenase reductase Sdr
H0E72_RS18045	COG0183	Belongs to the thiolase family
H0E72_RS18050	COG0814	amino acid
H0E72_RS18055	COG2771	luxR family
H0E72_RS18060	COG3710	Transcriptional regulator
H0E72_RS18085	COG0457	Tetratricopeptide repeat
H0E72_RS18090	COG3710	Transcriptional regulator
H0E72_RS18090	COG0457	Tetratricopeptide repeat
H0E72_RS18185	COG3387	PFAM Glycoside hydrolase 15-related
H0E72_RS18195	COG4942	peptidase
H0E72_RS18200	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H0E72_RS18205	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
H0E72_RS18210	COG2080	2 iron, 2 sulfur cluster binding
H0E72_RS18220	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
H0E72_RS18225	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H0E72_RS18230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H0E72_RS18240	COG0549	Belongs to the carbamate kinase family
H0E72_RS18245	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
H0E72_RS18245	COG3608	succinylglutamate desuccinylase aspartoacylase
H0E72_RS18250	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H0E72_RS18255	COG2068	MobA-Related Protein
H0E72_RS18260	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H0E72_RS18260	COG0493	'glutamate synthase
H0E72_RS18265	COG0402	S-adenosylhomocysteine deaminase activity
H0E72_RS18270	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
H0E72_RS18275	COG2080	2 iron, 2 sulfur cluster binding
H0E72_RS18275	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H0E72_RS18280	COG2233	PERMEase
H0E72_RS18285	COG0402	S-adenosylhomocysteine deaminase activity
H0E72_RS18290	COG2252	PERMEase
H0E72_RS18295	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H0E72_RS18305	COG2233	PERMEase
H0E72_RS18335	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H0E72_RS18340	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H0E72_RS18345	COG4974	Belongs to the 'phage' integrase family
H0E72_RS18350	COG0716	FMN binding
H0E72_RS18360	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
H0E72_RS18370	COG1272	protein, Hemolysin III
H0E72_RS18380	COG2723	6-phospho-beta-galactosidase activity
H0E72_RS18385	COG1028	Short-chain dehydrogenase reductase Sdr
H0E72_RS18410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H0E72_RS18415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H0E72_RS18420	COG0006	proline dipeptidase activity
H0E72_RS18440	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H0E72_RS18455	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H0E72_RS18475	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
H0E72_RS18475	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
H0E72_RS18480	COG1703	isobutyryl-CoA mutase activity
H0E72_RS18485	COG1024	Enoyl-CoA hydratase
H0E72_RS18490	COG0427	acetyl-CoA hydrolase
H0E72_RS18495	COG0583	DNA-binding transcription factor activity
H0E72_RS18500	COG2968	Membrane
H0E72_RS18510	COG0668	transmembrane transport
H0E72_RS18515	COG0191	fructose-bisphosphate aldolase activity
H0E72_RS18545	COG1122	ATPase activity
H0E72_RS18550	COG1122	ATPase activity
H0E72_RS18555	COG1072	(Pantothenic acid kinase))
H0E72_RS18565	COG1494	fructose-1,6-bisphosphatase
H0E72_RS18570	COG1063	alcohol dehydrogenase
H0E72_RS18575	COG2213	PTS system mannitol-specific
H0E72_RS18580	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H0E72_RS18585	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H0E72_RS18590	COG0501	Belongs to the peptidase M48B family
H0E72_RS18605	COG1166	arginine decarboxylase activity
H0E72_RS18625	COG2814	Major facilitator Superfamily
H0E72_RS18635	COG2356	endonuclease I
H0E72_RS18640	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H0E72_RS18645	COG0189	ligase activity
H0E72_RS18660	COG2805	Type II/IV secretion system protein
H0E72_RS18665	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
H0E72_RS18670	COG0762	integral membrane protein
H0E72_RS18680	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
H0E72_RS18685	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H0E72_RS18695	COG0252	asparaginase activity
H0E72_RS18705	COG3171	Protein conserved in bacteria
H0E72_RS18715	COG1194	a g-specific adenine glycosylase
H0E72_RS18730	COG2211	Major facilitator Superfamily
H0E72_RS18735	COG1982	Orn Lys Arg decarboxylase major
H0E72_RS18740	COG1811	Na channel or pump
H0E72_RS18750	COG0582	viral genome integration into host DNA
H0E72_RS18780	COG0531	amino acid
H0E72_RS18785	COG1982	Orn Lys Arg decarboxylase major
H0E72_RS18790	COG0531	amino acid
H0E72_RS18800	COG3039	Transposase
H0E72_RS18805	COG0604	alcohol dehydrogenase
H0E72_RS18840	COG3039	Transposase
H0E72_RS18855	COG2831	hemolysin activation secretion protein
H0E72_RS18880	COG4869	propanediol catabolic process
H0E72_RS18885	COG4820	ethanolamine utilization protein (EutJ)
H0E72_RS18920	COG1012	belongs to the aldehyde dehydrogenase family
H0E72_RS18930	COG0693	protein deglycase activity
H0E72_RS18935	COG1882	Formate acetyltransferase
H0E72_RS18940	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H0E72_RS18955	COG3344	reverse transcriptase
H0E72_RS18960	COG2972	Histidine kinase
H0E72_RS18965	COG2207	Transcriptional regulator
H0E72_RS18970	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
H0E72_RS19025	COG3596	GTP binding
H0E72_RS19030	COG2378	regulation of single-species biofilm formation
H0E72_RS19055	COG2003	Belongs to the UPF0758 family
H0E72_RS19150	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
H0E72_RS19165	COG4795	General secretion pathway protein
H0E72_RS19180	COG2165	general secretion pathway protein
H0E72_RS19185	COG1459	type II secretion system
H0E72_RS19190	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H0E72_RS19215	COG3064	Membrane
H0E72_RS19220	COG1620	l-lactate permease
H0E72_RS19225	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H0E72_RS19230	COG3193	protein, possibly involved in utilization of glycolate and propanediol
H0E72_RS19235	COG0247	lactate metabolic process
H0E72_RS19240	COG0277	FAD linked oxidase domain protein
H0E72_RS19245	COG0277	FAD linked oxidase domain protein
H0E72_RS19250	COG2186	Transcriptional regulator
H0E72_RS19255	COG0456	acetyltransferase
H0E72_RS19260	COG0318	PFAM AMP-dependent synthetase and ligase
H0E72_RS19270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H0E72_RS19275	COG0156	8-amino-7-oxononanoate synthase activity
H0E72_RS19285	COG0795	lipopolysaccharide-transporting ATPase activity
H0E72_RS19290	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
H0E72_RS19300	COG2244	polysaccharide biosynthetic process
H0E72_RS19305	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
H0E72_RS19310	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
H0E72_RS19315	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
H0E72_RS19320	COG0306	phosphate transporter
H0E72_RS19325	COG0754	glutathionylspermidine amidase activity
H0E72_RS19330	COG0625	glutathione transferase activity
H0E72_RS19340	COG0298	carbon dioxide binding
H0E72_RS19350	COG1773	rubredoxin
H0E72_RS19355	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
H0E72_RS19360	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
H0E72_RS19365	COG5557	Pfam Polysulphide reductase, NrfD
H0E72_RS19370	COG0437	4 iron, 4 sulfur cluster binding
H0E72_RS19375	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
H0E72_RS19390	COG0667	Aldo Keto reductase
H0E72_RS19400	COG1028	Short-chain dehydrogenase reductase Sdr
H0E72_RS19405	COG0848	biopolymer transport protein
H0E72_RS19410	COG0811	peptide transport
H0E72_RS19415	COG0626	cystathionine gamma-synthase activity
H0E72_RS19420	COG0586	Pfam SNARE associated Golgi protein
H0E72_RS19425	COG2207	Transcriptional regulator
H0E72_RS19430	COG1979	alcohol dehydrogenase
H0E72_RS19435	COG0656	L-ascorbic acid biosynthetic process
H0E72_RS19445	COG4238	major outer membrane lipoprotein
H0E72_RS19450	COG1032	radical SAM domain protein
H0E72_RS19455	COG2186	Transcriptional regulator
H0E72_RS19460	COG0246	Mannitol dehydrogenase
H0E72_RS19465	COG1063	alcohol dehydrogenase
H0E72_RS19470	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
H0E72_RS19490	COG2132	Multicopper oxidase
H0E72_RS19495	COG0204	Acyl-transferase
H0E72_RS19500	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H0E72_RS19505	COG4166	transmembrane transport
H0E72_RS19510	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
H0E72_RS19515	COG3111	PFAM Bacterial OB fold (BOF) protein
H0E72_RS19520	COG0745	RESPONSE REGULATOR receiver
H0E72_RS19525	COG0642	Histidine kinase
H0E72_RS19530	COG2249	NAD(P)H dehydrogenase (quinone) activity
H0E72_RS19535	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H0E72_RS19540	COG1737	Transcriptional regulator
H0E72_RS19550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H0E72_RS19555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H0E72_RS19560	COG1120	ATPase activity
H0E72_RS19565	COG4774	siderophore transport
H0E72_RS19570	COG0187	DNA topoisomerase II activity
H0E72_RS19575	COG3150	esterase
H0E72_RS19580	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H0E72_RS19585	COG3151	Protein conserved in bacteria
H0E72_RS19590	COG0494	nUDIX hydrolase
H0E72_RS19595	COG1538	Outer membrane efflux protein
H0E72_RS19605	COG0754	glutathionylspermidine amidase activity
H0E72_RS19615	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H0E72_RS19625	COG3384	dioxygenase
H0E72_RS19655	COG1585	Membrane protein implicated in regulation of membrane protease activity
H0E72_RS19660	COG2268	Band 7 protein
H0E72_RS19685	COG3025	triphosphatase activity
H0E72_RS19690	COG4991	sh3 domain protein
H0E72_RS19705	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
H0E72_RS19720	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
H0E72_RS19725	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H0E72_RS19740	COG0828	Belongs to the bacterial ribosomal protein bS21 family
H0E72_RS19745	COG0358	DNA primase activity
H0E72_RS19750	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H0E72_RS19770	COG2375	cellular response to nickel ion
H0E72_RS19775	COG1695	Transcriptional regulator
H0E72_RS19780	COG0840	transmembrane signaling receptor activity
H0E72_RS19790	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H0E72_RS19795	COG1609	Transcriptional regulator
H0E72_RS19800	COG3250	beta-galactosidase activity
H0E72_RS19805	COG2731	YhcH YjgK YiaL family protein
H0E72_RS19810	COG0531	amino acid
H0E72_RS19820	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
H0E72_RS19820	COG3408	Glycogen debranching enzyme
H0E72_RS19825	COG0446	pyridine nucleotide-disulphide oxidoreductase
H0E72_RS19825	COG1902	pentaerythritol trinitrate reductase activity
H0E72_RS19835	COG1451	nucleotide metabolic process
H0E72_RS19840	COG2949	membrane
H0E72_RS19845	COG0673	inositol 2-dehydrogenase activity
H0E72_RS19850	COG0861	Integral membrane protein TerC family
H0E72_RS19855	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
H0E72_RS19865	COG2721	sulfolactate sulfo-lyase activity
H0E72_RS19875	COG2271	Major facilitator Superfamily
H0E72_RS19900	COG2186	Transcriptional regulator
H0E72_RS19905	COG0586	Pfam SNARE associated Golgi protein
H0E72_RS19915	COG1422	Protein of unknown function (DUF1090)
H0E72_RS19920	COG4575	ribosome binding
H0E72_RS19925	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
H0E72_RS19935	COG2259	Doxx family
H0E72_RS19940	COG0435	Glutathione S-transferase
H0E72_RS19945	COG3152	Membrane
H0E72_RS19950	COG3152	Membrane
H0E72_RS19955	COG0583	DNA-binding transcription factor activity
H0E72_RS19960	COG1741	Belongs to the pirin family
H0E72_RS19975	COG0814	amino acid
H0E72_RS20000	COG3039	Transposase
H0E72_RS20015	COG1760	l-serine dehydratase
H0E72_RS20020	COG0251	oxidation-reduction process
H0E72_RS20025	COG1882	Formate acetyltransferase
H0E72_RS20030	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H0E72_RS20040	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H0E72_RS20045	COG0583	DNA-binding transcription factor activity
H0E72_RS20070	COG1929	Belongs to the glycerate kinase type-1 family
H0E72_RS20075	COG2084	Dehydrogenase
H0E72_RS20085	COG2271	Major facilitator Superfamily
H0E72_RS20090	COG2721	sulfolactate sulfo-lyase activity
H0E72_RS20095	COG2002	toxin-antitoxin pair type II binding
H0E72_RS20105	COG1349	DNA-binding transcription factor activity
H0E72_RS20115	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H0E72_RS20125	COG3716	PTS system mannose fructose sorbose family IID component
H0E72_RS20130	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
H0E72_RS20135	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
H0E72_RS20140	COG2222	sugar isomerase
H0E72_RS20150	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H0E72_RS20155	COG3715	PTS system
H0E72_RS20160	COG3716	PTS system mannose fructose sorbose family IID component
H0E72_RS20165	COG0363	glucosamine-6-phosphate deaminase activity
H0E72_RS20170	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
H0E72_RS20190	COG2823	Periplasmic or secreted lipoprotein
H0E72_RS20195	COG0701	Predicted permease
H0E72_RS20200	COG0702	epimerase
H0E72_RS20205	COG0693	protein deglycase activity
H0E72_RS20220	COG3153	acetyltransferase
H0E72_RS20225	COG3154	lipid carrier protein
H0E72_RS20230	COG0826	peptidase U32
H0E72_RS20235	COG0826	peptidase U32
H0E72_RS20240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H0E72_RS20245	COG0814	amino acid
H0E72_RS20250	COG0513	Belongs to the DEAD box helicase family
H0E72_RS20290	COG0195	Participates in both transcription termination and antitermination
H0E72_RS20310	COG2194	sulfuric ester hydrolase activity
H0E72_RS20320	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H0E72_RS20330	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H0E72_RS20335	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H0E72_RS20345	COG1534	Rna-binding protein
H0E72_RS20350	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H0E72_RS20355	COG2027	D-alanyl-D-alanine carboxypeptidase
H0E72_RS20365	COG0697	spore germination
H0E72_RS20380	COG0142	geranyltranstransferase activity
H0E72_RS20385	COG3423	Transcriptional regulator
H0E72_RS20395	COG5007	Belongs to the BolA IbaG family
H0E72_RS20400	COG3113	response to antibiotic
H0E72_RS20405	COG2854	intermembrane phospholipid transfer
H0E72_RS20410	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H0E72_RS20415	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H0E72_RS20420	COG1127	ABC transporter
H0E72_RS20425	COG0530	calcium, potassium:sodium antiporter activity
H0E72_RS20430	COG0517	IMP dehydrogenase activity
H0E72_RS20430	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H0E72_RS20435	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
H0E72_RS20440	COG3117	lipopolysaccharide transmembrane transporter activity
H0E72_RS20445	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
H0E72_RS20450	COG1137	ATPase activity
H0E72_RS20455	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
H0E72_RS20460	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
H0E72_RS20475	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H0E72_RS20480	COG0515	serine threonine protein kinase
H0E72_RS20490	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
H0E72_RS20495	COG5002	protein histidine kinase activity
H0E72_RS20495	COG2198	Histidine kinase
H0E72_RS20495	COG0784	Response regulator, receiver
H0E72_RS20500	COG1242	4 iron, 4 sulfur cluster binding
H0E72_RS20505	COG0070	glutamate synthase
H0E72_RS20505	COG0067	glutamate synthase
H0E72_RS20505	COG0069	glutamate synthase activity
H0E72_RS20510	COG0493	'glutamate synthase
H0E72_RS20525	COG0714	Associated with various cellular activities
H0E72_RS20535	COG3552	Protein containing von Willebrand factor type A (VWA) domain
H0E72_RS20550	COG2731	YhcH YjgK YiaL family protein
H0E72_RS20580	COG3069	C4-dicarboxylate transmembrane transporter activity
H0E72_RS20585	COG2969	positive regulation of protein catabolic process
H0E72_RS20590	COG0625	glutathione transferase activity
H0E72_RS20605	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
H0E72_RS20610	COG3105	Protein conserved in bacteria
H0E72_RS20615	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H0E72_RS20620	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H0E72_RS20640	COG2732	(Barnase) inhibitor
H0E72_RS20660	COG0583	DNA-binding transcription factor activity
H0E72_RS20665	COG0312	modulator of DNA gyrase
H0E72_RS20670	COG3164	Protein of unknown function
H0E72_RS20675	COG1530	ribonuclease E activity
H0E72_RS20685	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
H0E72_RS20690	COG1792	Involved in formation and maintenance of cell shape
H0E72_RS20695	COG1077	Cell shape determining protein MreB Mrl
H0E72_RS20700	COG2199	diguanylate cyclase activity
H0E72_RS20700	COG2200	EAL domain
H0E72_RS20705	COG0604	alcohol dehydrogenase
H0E72_RS20715	COG0511	ligase activity, forming carbon-carbon bonds
H0E72_RS20720	COG0439	Biotin carboxylase
H0E72_RS20725	COG3924	membrane
H0E72_RS20730	COG4145	pantothenate transmembrane transporter activity
H0E72_RS20740	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H0E72_RS20750	COG2189	Belongs to the N(4) N(6)-methyltransferase family
H0E72_RS20760	COG1309	transcriptional regulator
H0E72_RS20765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0E72_RS20780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H0E72_RS20785	COG4597	amino acid ABC transporter
H0E72_RS20790	COG0765	amino acid transport
H0E72_RS20795	COG1126	abc transporter atp-binding protein
H0E72_RS20835	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H0E72_RS20855	COG0551	DNA topoisomerase type I activity
H0E72_RS20865	COG0758	DNA mediated transformation
H0E72_RS20885	COG0569	domain protein
H0E72_RS20895	COG3036	rescue of stalled ribosome
H0E72_RS20900	COG0789	Transcriptional regulator
H0E72_RS20940	COG0201	protein transport
H0E72_RS21030	COG0089	rRNA binding
H0E72_RS21100	COG2964	Protein conserved in bacteria
H0E72_RS21105	COG0545	Peptidyl-prolyl cis-trans isomerase
H0E72_RS21115	COG1047	Peptidyl-prolyl cis-trans
H0E72_RS21120	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
H0E72_RS21135	COG0488	(ABC) transporter
H0E72_RS21140	COG0429	hydrolase of the alpha beta-hydrolase fold
H0E72_RS21150	COG3954	Phosphoribulokinase
H0E72_RS21155	COG1765	OsmC-like protein
H0E72_RS21160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H0E72_RS21165	COG1289	transmembrane transporter activity
H0E72_RS21170	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H0E72_RS21175	COG0512	Glutamine amidotransferase of anthranilate synthase
H0E72_RS21180	COG2184	nucleotidyltransferase activity
H0E72_RS21190	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H0E72_RS21200	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H0E72_RS21205	COG2146	nitrite reductase [NAD(P)H] activity
H0E72_RS21210	COG2116	formate transmembrane transporter activity
H0E72_RS21225	COG0626	cystathionine gamma-synthase activity
H0E72_RS21240	COG1735	metal-dependent hydrolase with the TIM-barrel fold
H0E72_RS21245	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
H0E72_RS21250	COG3457	Alanine racemase
H0E72_RS21260	COG2188	Transcriptional regulator
H0E72_RS21265	COG0180	Tryptophanyl-tRNA synthetase
H0E72_RS21275	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H0E72_RS21280	COG0338	D12 class N6 adenine-specific DNA methyltransferase
H0E72_RS21285	COG3266	domain, Protein
H0E72_RS21300	COG4796	Type ii and iii secretion system protein
H0E72_RS21315	COG3166	PFAM Fimbrial assembly family protein
H0E72_RS21320	COG4972	Pilus assembly protein
H0E72_RS21325	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
H0E72_RS21330	COG0494	nUDIX hydrolase
H0E72_RS21340	COG1011	Hydrolase
H0E72_RS21345	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H0E72_RS21355	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
H0E72_RS21375	COG2205	protein histidine kinase activity
H0E72_RS21380	COG0745	RESPONSE REGULATOR receiver
H0E72_RS21385	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H0E72_RS21390	COG2183	response to ionizing radiation
H0E72_RS21395	COG1918	ferrous iron import across plasma membrane
H0E72_RS21400	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
H0E72_RS21410	COG5464	transposase or invertase
H0E72_RS21420	COG1040	competence protein
H0E72_RS21430	COG2610	gluconate transmembrane transporter activity
H0E72_RS21435	COG1640	4-alpha-glucanotransferase
H0E72_RS21440	COG0058	SHG alpha-glucan phosphorylase activity
H0E72_RS21455	COG1690	Belongs to the RtcB family
H0E72_RS21460	COG4650	regulator
H0E72_RS21465	COG1349	DNA-binding transcription factor activity
H0E72_RS21480	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
H0E72_RS21495	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H0E72_RS21500	COG0058	SHG alpha-glucan phosphorylase activity
H0E72_RS21520	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
H0E72_RS21525	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H0E72_RS21530	COG2095	MarC family integral membrane protein
H0E72_RS21540	COG0514	ATP-dependent DNA helicase (RecQ)
H0E72_RS21545	COG2610	gluconate transmembrane transporter activity
H0E72_RS21550	COG3265	gluconokinase activity
H0E72_RS21555	COG1609	Transcriptional regulator
H0E72_RS21560	COG1741	Belongs to the pirin family
H0E72_RS21565	COG0673	inositol 2-dehydrogenase activity
H0E72_RS21570	COG1247	-acetyltransferase
H0E72_RS21575	COG0405	Gamma-glutamyltransferase
H0E72_RS21585	COG0584	glycerophosphoryl diester phosphodiesterase
H0E72_RS21615	COG0410	ABC transporter
H0E72_RS21620	COG0411	ABC transporter
H0E72_RS21625	COG4177	L-phenylalanine transmembrane transporter activity
H0E72_RS21630	COG0559	Belongs to the binding-protein-dependent transport system permease family
H0E72_RS21635	COG0683	leucine binding
H0E72_RS21640	COG0456	acetyltransferase
H0E72_RS21645	COG0683	leucine binding
H0E72_RS21650	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H0E72_RS21655	COG2177	Part of the ABC transporter FtsEX involved in
H0E72_RS21660	COG2884	Cell division ATP-binding protein ftsE
H0E72_RS21665	COG0552	protein localization to endoplasmic reticulum
H0E72_RS21670	COG0742	ribosomal rna small subunit methyltransferase
H0E72_RS21675	COG3776	membrane
H0E72_RS21685	COG3714	YhhN family
H0E72_RS21705	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
H0E72_RS21715	COG0477	Major facilitator Superfamily
H0E72_RS21720	COG0628	permease
H0E72_RS21725	COG2091	lysine biosynthetic process via aminoadipic acid
H0E72_RS21730	COG0747	negative chemotaxis
H0E72_RS21735	COG0601	transmembrane transport
H0E72_RS21740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H0E72_RS21760	COG2188	Transcriptional regulator
H0E72_RS21770	COG3414	Phosphotransferase system galactitol-specific IIB component
H0E72_RS21775	COG3775	system Galactitol-specific IIC component
H0E72_RS21780	COG1070	Carbohydrate kinase
H0E72_RS21790	COG0191	fructose-bisphosphate aldolase activity
H0E72_RS21805	COG0842	Transport permease protein
H0E72_RS21810	COG0842	Transport permease protein
H0E72_RS21810	COG1129	ABC transporter
H0E72_RS21815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0E72_RS21835	COG2081	HI0933 family
H0E72_RS21840	COG0306	phosphate transporter
H0E72_RS21850	COG0589	response to stress
H0E72_RS21855	COG3104	oligopeptide transport
H0E72_RS21865	COG0339	signal peptide processing
H0E72_RS21870	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
H0E72_RS21875	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H0E72_RS21885	COG0640	Transcriptional regulator
H0E72_RS21890	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
H0E72_RS21895	COG1393	Belongs to the ArsC family
H0E72_RS21915	COG3065	identical protein binding
H0E72_RS21920	COG2197	response regulator
H0E72_RS21925	COG3720	iron ion transport
H0E72_RS21930	COG4771	TonB-dependent receptor
H0E72_RS21945	COG3721	Heme iron utilization protein
H0E72_RS21955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H0E72_RS21965	COG1285	pathogenesis
H0E72_RS21980	COG3247	response to pH
H0E72_RS21985	COG2771	luxR family
H0E72_RS21995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0E72_RS22000	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H0E72_RS22005	COG2207	Transcriptional regulator
H0E72_RS22015	COG0076	glutamate decarboxylase activity
H0E72_RS22020	COG1858	cytochrome C peroxidase
H0E72_RS22030	COG2197	response regulator
H0E72_RS22035	COG0583	DNA-binding transcription factor activity
H0E72_RS22040	COG1295	ribonuclease BN
H0E72_RS22045	COG0477	Major facilitator Superfamily
H0E72_RS22050	COG2982	Protein involved in outer membrane biogenesis
H0E72_RS22055	COG2200	EAL domain
H0E72_RS22060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H0E72_RS22080	COG0612	Peptidase, M16
H0E72_RS22090	COG2199	diguanylate cyclase activity
H0E72_RS22090	COG2200	EAL domain
H0E72_RS22095	COG0457	Tetratricopeptide repeat
H0E72_RS22095	COG3118	belongs to the thioredoxin family
H0E72_RS22100	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
H0E72_RS22105	COG1215	transferase activity, transferring glycosyl groups
H0E72_RS22110	COG1215	transferase activity, transferring glycosyl groups
H0E72_RS22135	COG2194	sulfuric ester hydrolase activity
H0E72_RS22165	COG0814	amino acid
H0E72_RS22170	COG4608	Belongs to the ABC transporter superfamily
H0E72_RS22175	COG0444	Belongs to the ABC transporter superfamily
H0E72_RS22180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H0E72_RS22185	COG0601	transmembrane transport
H0E72_RS22190	COG0747	negative chemotaxis
H0E72_RS22200	COG2194	sulfuric ester hydrolase activity
H0E72_RS22205	COG2223	nitrite transmembrane transporter activity
H0E72_RS22210	COG5571	outer membrane autotransporter
H0E72_RS22215	COG2818	Glycosylase
H0E72_RS22220	COG0456	acetyltransferase
H0E72_RS22225	COG0243	molybdopterin cofactor binding
H0E72_RS22230	COG2885	chlorophyll binding
H0E72_RS22245	COG2944	sequence-specific DNA binding
H0E72_RS22250	COG1278	Cold shock
H0E72_RS22280	COG3274	enterobacterial common antigen metabolic process
H0E72_RS22285	COG4682	membrane
H0E72_RS22290	COG4682	membrane
H0E72_RS22295	COG1070	Carbohydrate kinase
H0E72_RS22305	COG4213	ABC transporter substrate-binding protein
H0E72_RS22315	COG4214	carbohydrate transport
H0E72_RS22320	COG2207	Transcriptional regulator
H0E72_RS22320	COG1609	Transcriptional regulator
H0E72_RS22325	COG2992	FlgJ-related protein
H0E72_RS22330	COG0366	Alpha amylase catalytic
H0E72_RS22335	COG3977	Valine--pyruvate aminotransferase
H0E72_RS22340	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H0E72_RS22345	COG1414	Transcriptional regulator
H0E72_RS22355	COG2731	YhcH YjgK YiaL family protein
H0E72_RS22360	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
H0E72_RS22365	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
H0E72_RS22370	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H0E72_RS22375	COG1070	Carbohydrate kinase
H0E72_RS22380	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
H0E72_RS22385	COG3623	hexulose-6-phosphate isomerase
H0E72_RS22390	COG0235	Class ii aldolase
H0E72_RS22400	COG2211	Major facilitator Superfamily
H0E72_RS22410	COG3713	MltA-interacting MipA family protein
H0E72_RS22415	COG0583	DNA-binding transcription factor activity
H0E72_RS22420	COG1566	PFAM secretion protein HlyD family protein
H0E72_RS22435	COG1012	belongs to the aldehyde dehydrogenase family
H0E72_RS22445	COG1454	alcohol dehydrogenase
H0E72_RS22450	COG3276	selenocysteine insertion sequence binding
H0E72_RS22460	COG0625	glutathione transferase activity
H0E72_RS22465	COG3468	outer membrane autotransporter barrel domain protein
H0E72_RS22465	COG3210	domain, Protein
H0E72_RS22510	COG1566	PFAM secretion protein HlyD family protein
H0E72_RS22520	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H0E72_RS22520	COG2213	PTS system mannitol-specific
H0E72_RS22530	COG3722	fumarate hydratase activity
H0E72_RS22550	COG5295	Hep Hag repeat protein
H0E72_RS22555	COG1620	l-lactate permease
H0E72_RS22560	COG2186	Transcriptional regulator
H0E72_RS22570	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H0E72_RS22575	COG1045	serine acetyltransferase
H0E72_RS22590	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H0E72_RS22595	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H0E72_RS22605	COG4942	peptidase
H0E72_RS22610	COG2861	carbohydrate metabolic process
H0E72_RS22615	COG1216	Glycosyl transferase, family 2
H0E72_RS22625	COG0156	8-amino-7-oxononanoate synthase activity
H0E72_RS22635	COG0859	PFAM glycosyl transferase family 9
H0E72_RS22640	COG0859	PFAM glycosyl transferase family 9
H0E72_RS22645	COG3307	-O-antigen
H0E72_RS22650	COG1216	Glycosyl transferase, family 2
H0E72_RS22655	COG1442	glycosyl transferase family 8
H0E72_RS22660	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H0E72_RS22675	COG0515	serine threonine protein kinase
H0E72_RS22680	COG0438	transferase activity, transferring glycosyl groups
H0E72_RS22685	COG0859	PFAM glycosyl transferase family 9
H0E72_RS22690	COG1519	Transferase
H0E72_RS22720	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H0E72_RS22745	COG1561	YicC-like family, N-terminal region
H0E72_RS22750	COG3645	SOS response
H0E72_RS22755	COG2860	membrane
H0E72_RS22765	COG0194	GDP metabolic process
H0E72_RS22775	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H0E72_RS22780	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H0E72_RS22785	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H0E72_RS22790	COG0786	glutamate:sodium symporter activity
H0E72_RS22795	COG2233	PERMEase
H0E72_RS22800	COG2982	Protein involved in outer membrane biogenesis
H0E72_RS22810	COG1940	carbohydrate kinase activity
H0E72_RS22825	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H0E72_RS22825	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H0E72_RS22830	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H0E72_RS22835	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H0E72_RS22835	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H0E72_RS22835	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H0E72_RS22840	COG3711	transcriptional antiterminator
H0E72_RS22845	COG1501	Belongs to the glycosyl hydrolase 31 family
H0E72_RS22850	COG2211	Major facilitator Superfamily
H0E72_RS22860	COG0582	viral genome integration into host DNA
H0E72_RS22870	COG2194	sulfuric ester hydrolase activity
H0E72_RS22895	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
H0E72_RS22950	COG3547	Transposase (IS116 IS110 IS902 family)
H0E72_RS22960	COG3436	PFAM IS66 Orf2 family protein
H0E72_RS23030	COG2916	Histone family protein nucleoid-structuring protein H-NS
H0E72_RS23065	COG3596	GTP binding
H0E72_RS23070	COG2378	regulation of single-species biofilm formation
H0E72_RS23095	COG2003	Belongs to the UPF0758 family
H0E72_RS23135	COG2814	Major facilitator Superfamily
H0E72_RS23140	COG0697	spore germination
H0E72_RS23145	COG1464	Belongs to the NlpA lipoprotein family
H0E72_RS23155	COG0457	Tetratricopeptide repeat
H0E72_RS23185	COG1388	LysM domain
H0E72_RS23185	COG2373	Large extracellular alpha-helical protein
H0E72_RS23185	COG4932	domain protein
H0E72_RS23210	COG2252	PERMEase
H0E72_RS23220	COG2271	Major facilitator Superfamily
H0E72_RS23225	COG2271	Major facilitator Superfamily
H0E72_RS23230	COG3851	Histidine kinase
H0E72_RS23235	COG2197	response regulator
H0E72_RS23250	COG0440	acetolactate synthase activity
H0E72_RS23255	COG0028	Belongs to the TPP enzyme family
H0E72_RS23270	COG2814	Major facilitator Superfamily
H0E72_RS23275	COG0641	radical SAM
H0E72_RS23285	COG2149	membrane
H0E72_RS23290	COG3119	arylsulfatase activity
H0E72_RS23295	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H0E72_RS23300	COG2207	Transcriptional regulator
H0E72_RS23315	COG2188	Transcriptional regulator
H0E72_RS23335	COG5645	(Lipo)protein
H0E72_RS23340	COG0823	Involved in the tonB-independent uptake of proteins
H0E72_RS23350	COG2271	Major facilitator Superfamily
H0E72_RS23360	COG0800	Aldolase
H0E72_RS23365	COG3734	2-keto-3-deoxy-galactonokinase
H0E72_RS23370	COG2186	Transcriptional regulator
H0E72_RS23380	COG0561	phosphatase activity
H0E72_RS23385	COG3753	Protein conserved in bacteria
H0E72_RS23390	COG0187	DNA topoisomerase II activity
H0E72_RS23400	COG0592	DNA-directed DNA polymerase activity
H0E72_RS23460	COG0583	DNA-binding transcription factor activity
H0E72_RS23465	COG2091	lysine biosynthetic process via aminoadipic acid
H0E72_RS23470	COG0431	NADPH-dependent FMN reductase
H0E72_RS23475	COG2252	PERMEase
H0E72_RS23480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H0E72_RS23505	COG0704	Plays a role in the regulation of phosphate uptake
H0E72_RS23510	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H0E72_RS23515	COG0581	inorganic phosphate transmembrane transporter activity
H0E72_RS23520	COG0573	inorganic phosphate transmembrane transporter activity
H0E72_RS23525	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H0E72_RS23600	COG3312	ion transport
H0E72_RS23615	COG0716	FMN binding
H0E72_RS23620	COG1522	sequence-specific DNA binding
H0E72_RS23640	COG3385	transposase activity
H0E72_RS23655	COG1129	ABC transporter
H0E72_RS23660	COG1172	Belongs to the binding-protein-dependent transport system permease family
H0E72_RS23665	COG1879	ABC-type sugar transport system periplasmic component
H0E72_RS23670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H0E72_RS23675	COG1609	Transcriptional regulator
H0E72_RS23680	COG0477	Major facilitator Superfamily
H0E72_RS23685	COG2186	Transcriptional regulator
H0E72_RS23725	COG3085	chromosome segregation
H0E72_RS23730	COG0606	chelatase, subunit chli
H0E72_RS23750	COG3978	acetolactate synthase activity
H0E72_RS23755	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H0E72_RS23765	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H0E72_RS23770	COG0583	DNA-binding transcription factor activity
H0E72_RS23780	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H0E72_RS23785	COG3692	DNA binding
H0E72_RS23790	COG0210	DNA helicase
H0E72_RS23805	COG3118	belongs to the thioredoxin family
H0E72_RS23815	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
H0E72_RS23820	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H0E72_RS23825	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
H0E72_RS23830	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
H0E72_RS23835	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
H0E72_RS23840	COG1088	dTDP-glucose 4,6-dehydratase activity
H0E72_RS23845	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
H0E72_RS23850	COG0456	acetyltransferase
H0E72_RS23855	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H0E72_RS23860	COG2244	polysaccharide biosynthetic process
H0E72_RS23880	COG1113	amino acid transport
H0E72_RS23905	COG0641	radical SAM
H0E72_RS23910	COG3119	arylsulfatase activity
H0E72_RS23915	COG3071	HemY protein
H0E72_RS23920	COG2959	enzyme of heme biosynthesis
H0E72_RS23925	COG1587	Uroporphyrinogen-III synthase
H0E72_RS23935	COG3072	Adenylate cyclase
H0E72_RS23950	COG5567	small periplasmic lipoprotein
H0E72_RS23960	COG3159	Protein conserved in bacteria
H0E72_RS23970	COG1011	Hydrolase
H0E72_RS23975	COG0210	DNA helicase
H0E72_RS23980	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
H0E72_RS23985	COG3698	Phosphodiester glycosidase
H0E72_RS23990	COG0598	Magnesium transport protein CorA
H0E72_RS24005	COG2962	Rard protein
H0E72_RS24010	COG2050	protein possibly involved in aromatic compounds catabolism
H0E72_RS24015	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
H0E72_RS24020	COG0514	ATP-dependent DNA helicase (RecQ)
H0E72_RS24025	COG1280	lysine exporter protein (LysE YggA)
H0E72_RS24030	COG1280	lysine exporter protein (LysE YggA)
H0E72_RS24035	COG2267	carboxylic ester hydrolase activity
H0E72_RS24040	COG0561	phosphatase activity
H0E72_RS24045	COG0697	spore germination
H0E72_RS24050	COG0583	DNA-binding transcription factor activity
H0E72_RS24060	COG0583	DNA-binding transcription factor activity
H0E72_RS24065	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H0E72_RS24075	COG0549	Belongs to the carbamate kinase family
H0E72_RS24080	COG1304	FMN binding
H0E72_RS24095	COG1335	isochorismatase
H0E72_RS24100	COG0412	Dienelactone hydrolase
H0E72_RS24105	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
H0E72_RS24125	COG0800	Aldolase
H0E72_RS24130	COG3734	2-keto-3-deoxy-galactonokinase
H0E72_RS24135	COG1414	Transcriptional regulator
H0E72_RS24140	COG1322	Protein conserved in bacteria
H0E72_RS24150	COG3165	ubiquinone biosynthetic process from chorismate
H0E72_RS24160	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H0E72_RS24165	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H0E72_RS24170	COG0805	protein transport
H0E72_RS24180	COG0250	Participates in transcription elongation, termination and antitermination
H0E72_RS24185	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
H0E72_RS24190	COG0543	2 iron, 2 sulfur cluster binding
H0E72_RS24210	COG1739	Uncharacterized protein family UPF0029
H0E72_RS24215	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H0E72_RS24220	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
H0E72_RS24250	COG1763	Mo-molybdopterin cofactor biosynthetic process
H0E72_RS24255	COG0746	molybdenum cofactor guanylyltransferase activity
H0E72_RS24260	COG3084	Protein conserved in bacteria
H0E72_RS24265	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H0E72_RS24270	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H0E72_RS24280	COG0204	Acyl-transferase
H0E72_RS24285	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H0E72_RS24285	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H0E72_RS24300	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H0E72_RS24310	COG2204	response regulator
H0E72_RS24315	COG3852	Histidine kinase
H0E72_RS24320	COG0174	glutamine synthetase
H0E72_RS24330	COG2188	Transcriptional regulator
H0E72_RS24335	COG1082	Xylose isomerase domain protein TIM barrel
H0E72_RS24340	COG2271	Major facilitator Superfamily
H0E72_RS24345	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
H0E72_RS24350	COG2211	Major facilitator Superfamily
H0E72_RS24355	COG2211	Major facilitator Superfamily
H0E72_RS24360	COG1501	Belongs to the glycosyl hydrolase 31 family
H0E72_RS24365	COG2017	converts alpha-aldose to the beta-anomer
H0E72_RS24370	COG2942	2-epimerase
H0E72_RS24375	COG3684	Belongs to the aldolase LacD family
H0E72_RS24380	COG2084	Dehydrogenase
H0E72_RS24385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H0E72_RS24390	COG1349	DNA-binding transcription factor activity
H0E72_RS24395	COG1011	Hydrolase
H0E72_RS24410	COG0456	acetyltransferase
H0E72_RS24425	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H0E72_RS24435	COG2864	formate dehydrogenase
H0E72_RS24440	COG0437	4 iron, 4 sulfur cluster binding
H0E72_RS24455	COG0326	Molecular chaperone. Has ATPase activity
H0E72_RS24470	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H0E72_RS24470	COG3711	transcriptional antiterminator
H0E72_RS24475	COG1363	Peptidase, m42
H0E72_RS24480	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H0E72_RS24480	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H0E72_RS24485	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H0E72_RS24520	COG1917	Cupin 2, conserved barrel domain protein
H0E72_RS24520	COG4977	sequence-specific DNA binding
H0E72_RS24530	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H0E72_RS24540	COG2258	MOSC domain
H0E72_RS24545	COG2205	protein histidine kinase activity
H0E72_RS24550	COG0745	RESPONSE REGULATOR receiver
H0E72_RS24555	COG3678	ATP-independent chaperone mediated protein folding
H0E72_RS24560	COG4974	Belongs to the 'phage' integrase family
H0E72_RS24860	COG3436	PFAM IS66 Orf2 family protein
H0E72_RS24865	COG4372	Transposase
H0E72_RS24925	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H0E72_RS25035	COG2805	Type II/IV secretion system protein
H0E72_RS25085	COG0741	lytic transglycosylase activity
H0E72_RS25100	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H0E72_RS25205	COG1414	Transcriptional regulator
H0E72_RS25230	COG1175	transmembrane transport
H0E72_RS25235	COG0395	ABC-type sugar transport system, permease component
H0E72_RS25240	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H0E72_RS25245	COG3842	ATPase activity
H0E72_RS25290	COG0577	efflux transmembrane transporter activity
H0E72_RS25290	COG1136	(ABC) transporter
H0E72_RS25295	COG1136	(ABC) transporter
H0E72_RS25295	COG0577	efflux transmembrane transporter activity
H0E72_RS25300	COG0577	efflux transmembrane transporter activity
H0E72_RS25300	COG1136	(ABC) transporter
H0E72_RS25315	COG0672	)-iron permease
H0E72_RS25320	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
H0E72_RS25325	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H0E72_RS25355	COG0640	Transcriptional regulator
H0E72_RS25425	COG1660	Displays ATPase and GTPase activities
H0E72_RS25590	COG1196	nuclear chromosome segregation
H0E72_RS25655	COG0484	heat shock protein binding
H0E72_RS25700	COG1192	Involved in chromosome partitioning
H0E72_RS25730	COG0673	inositol 2-dehydrogenase activity
H0E72_RS25750	COG3039	Transposase
H0E72_RS25755	COG2826	transposase and inactivated derivatives, IS30 family
H0E72_RS25815	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H0E72_RS25820	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H0E72_RS25850	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis