locus-tag	class	description
CXX03_RS00005	COG0587	DNA-directed DNA polymerase activity
CXX03_RS00035	COG4568	rho-dependent transcription termination
CXX03_RS00045	COG4681	YaeQ
CXX03_RS00050	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CXX03_RS00065	COG3547	Transposase (IS116 IS110 IS902 family)
CXX03_RS00070	COG0791	NLP P60 protein
CXX03_RS00080	COG1720	tRNA m6t6A37 methyltransferase activity
CXX03_RS00090	COG1464	Belongs to the NlpA lipoprotein family
CXX03_RS00095	COG2011	ABC-type metal ion transport system permease component
CXX03_RS00100	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CXX03_RS00105	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CXX03_RS00140	COG0656	L-ascorbic acid biosynthetic process
CXX03_RS00145	COG0583	DNA-binding transcription factor activity
CXX03_RS00155	COG2226	methyltransferase
CXX03_RS00160	COG0741	lytic transglycosylase activity
CXX03_RS00160	COG1388	LysM domain
CXX03_RS00170	COG2226	methyltransferase
CXX03_RS00180	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CXX03_RS00200	COG4104	PAAR repeat-containing protein
CXX03_RS00205	COG3157	Type VI secretion system effector, Hcp
CXX03_RS00295	COG3209	COG3209 Rhs family protein
CXX03_RS00320	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CXX03_RS00330	COG1960	acyl-CoA dehydrogenase activity
CXX03_RS00340	COG0121	glutamine amidotransferase
CXX03_RS00345	COG3034	peptidoglycan biosynthetic process
CXX03_RS00350	COG3041	Addiction module toxin RelE StbE family
CXX03_RS00355	COG3077	Addiction module antitoxin, RelB DinJ family
CXX03_RS00360	COG0791	NLP P60 protein
CXX03_RS00390	COG0454	-acetyltransferase
CXX03_RS00395	COG1690	Belongs to the RtcB family
CXX03_RS00400	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CXX03_RS00405	COG2195	Cleaves the N-terminal amino acid of tripeptides
CXX03_RS00425	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CXX03_RS00525	COG0583	DNA-binding transcription factor activity
CXX03_RS00530	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CXX03_RS00535	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CXX03_RS00540	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CXX03_RS00545	COG2080	2 iron, 2 sulfur cluster binding
CXX03_RS00555	COG0727	PFAM Uncharacterised protein family (UPF0153)
CXX03_RS00560	COG3121	Chaperone
CXX03_RS00570	COG3188	usher protein
CXX03_RS00615	COG1388	LysM domain
CXX03_RS00620	COG3708	Transcriptional regulator
CXX03_RS00620	COG2207	Transcriptional regulator
CXX03_RS00625	COG0656	L-ascorbic acid biosynthetic process
CXX03_RS00630	COG3059	membrane
CXX03_RS00640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CXX03_RS00645	COG2207	Transcriptional regulator
CXX03_RS00650	COG0247	lactate metabolic process
CXX03_RS00655	COG1139	Iron-sulfur cluster binding protein
CXX03_RS00660	COG1556	Lactate utilization protein
CXX03_RS00685	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CXX03_RS00695	COG2200	EAL domain
CXX03_RS00695	COG2771	luxR family
CXX03_RS00700	COG0583	DNA-binding transcription factor activity
CXX03_RS00710	COG0666	response to abiotic stimulus
CXX03_RS00725	COG1304	FMN binding
CXX03_RS00730	COG0549	Belongs to the carbamate kinase family
CXX03_RS00735	COG0402	S-adenosylhomocysteine deaminase activity
CXX03_RS00745	COG1879	ABC-type sugar transport system periplasmic component
CXX03_RS00750	COG1129	ABC transporter
CXX03_RS00755	COG1172	Belongs to the binding-protein-dependent transport system permease family
CXX03_RS00765	COG1064	alcohol dehydrogenase
CXX03_RS00780	COG1280	lysine exporter protein (LysE YggA)
CXX03_RS00790	COG3829	transcription factor binding
CXX03_RS00795	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CXX03_RS00800	COG0372	Belongs to the citrate synthase family
CXX03_RS00805	COG2079	MmgE PrpD family protein
CXX03_RS00810	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CXX03_RS00815	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CXX03_RS00820	COG0402	S-adenosylhomocysteine deaminase activity
CXX03_RS00825	COG0583	DNA-binding transcription factor activity
CXX03_RS00830	COG0288	reversible hydration of carbon dioxide
CXX03_RS00840	COG2807	transmembrane transport
CXX03_RS00845	COG2223	nitrite transmembrane transporter activity
CXX03_RS00855	COG1609	Transcriptional regulator
CXX03_RS00860	COG1414	Transcriptional regulator
CXX03_RS00895	COG2814	Major facilitator Superfamily
CXX03_RS00900	COG3122	Protein conserved in bacteria
CXX03_RS00930	COG1215	transferase activity, transferring glycosyl groups
CXX03_RS00935	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CXX03_RS00940	COG4521	taurine ABC transporter
CXX03_RS00950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CXX03_RS00955	COG2175	clavaminate synthase activity
CXX03_RS00960	COG0113	porphobilinogen synthase activity
CXX03_RS00975	COG3468	outer membrane autotransporter barrel domain protein
CXX03_RS00980	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CXX03_RS00985	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CXX03_RS00990	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CXX03_RS01010	COG1181	Belongs to the D-alanine--D-alanine ligase family
CXX03_RS01020	COG1785	Belongs to the alkaline phosphatase family
CXX03_RS01030	COG3706	GGDEF domain
CXX03_RS01035	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CXX03_RS01055	COG4126	flavin adenine dinucleotide binding
CXX03_RS01075	COG1940	carbohydrate kinase activity
CXX03_RS01080	COG2814	Major facilitator Superfamily
CXX03_RS01085	COG0419	ATPase involved in DNA repair
CXX03_RS01090	COG0420	3'-5' exonuclease activity
CXX03_RS01095	COG0745	RESPONSE REGULATOR receiver
CXX03_RS01100	COG5002	protein histidine kinase activity
CXX03_RS01105	COG1114	Component of the transport system for branched-chain amino acids
CXX03_RS01110	COG1113	amino acid transport
CXX03_RS01115	COG0366	Alpha amylase catalytic
CXX03_RS01135	COG1862	Preprotein translocase
CXX03_RS01140	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CXX03_RS01145	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CXX03_RS01150	COG1403	HNH endonuclease
CXX03_RS01155	COG3248	Nucleoside-binding outer membrane protein
CXX03_RS01160	COG4238	major outer membrane lipoprotein
CXX03_RS01170	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CXX03_RS01170	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CXX03_RS01185	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CXX03_RS01190	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CXX03_RS01195	COG0667	Aldo Keto reductase
CXX03_RS01205	COG0142	geranyltranstransferase activity
CXX03_RS01220	COG0693	protein deglycase activity
CXX03_RS01225	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CXX03_RS01235	COG2814	Major facilitator Superfamily
CXX03_RS01260	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CXX03_RS01265	COG1845	cytochrome c oxidase, subunit III
CXX03_RS01270	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CXX03_RS01275	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CXX03_RS01280	COG2223	nitrite transmembrane transporter activity
CXX03_RS01285	COG3056	Lipoprotein
CXX03_RS01290	COG0271	Belongs to the BolA IbaG family
CXX03_RS01310	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CXX03_RS01315	COG0776	regulation of translation
CXX03_RS01320	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CXX03_RS01330	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CXX03_RS01345	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CXX03_RS01485	COG2369	cell adhesion
CXX03_RS01495	COG4373	Mu-like prophage FluMu protein gp28
CXX03_RS01575	COG3409	Peptidoglycan-binding domain 1 protein
CXX03_RS01575	COG3267	Type II secretory pathway component ExeA
CXX03_RS01585	COG4396	Host-nuclease inhibitor protein Gam
CXX03_RS01620	COG4382	Mu-like prophage protein Gp16
CXX03_RS01630	COG1555	photosystem II stabilization
CXX03_RS01635	COG0824	Thioesterase
CXX03_RS01645	COG4533	DNA binding
CXX03_RS01655	COG1522	sequence-specific DNA binding
CXX03_RS01660	COG1132	(ABC) transporter
CXX03_RS01665	COG1132	(ABC) transporter
CXX03_RS01670	COG0347	Belongs to the P(II) protein family
CXX03_RS01675	COG0004	ammonium transporteR
CXX03_RS01680	COG1946	Acyl-CoA thioesterase
CXX03_RS01685	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CXX03_RS01690	COG3695	enzyme binding
CXX03_RS01700	COG5507	3-demethylubiquinone-9 3-methyltransferase
CXX03_RS01705	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CXX03_RS01715	COG0110	maltose O-acetyltransferase activity
CXX03_RS01730	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CXX03_RS01735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CXX03_RS01740	COG1309	transcriptional regulator
CXX03_RS01745	COG1196	nuclear chromosome segregation
CXX03_RS01745	COG3264	Mechanosensitive ion channel
CXX03_RS01755	COG3923	Primosomal replication protein n
CXX03_RS01760	COG2832	Protein of unknown function (DUF454)
CXX03_RS01770	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CXX03_RS01805	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CXX03_RS01810	COG4651	solute:proton antiporter activity
CXX03_RS01810	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CXX03_RS01815	COG2223	nitrite transmembrane transporter activity
CXX03_RS01820	COG0737	Belongs to the 5'-nucleotidase family
CXX03_RS01825	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CXX03_RS01830	COG3735	TraB family
CXX03_RS01840	COG3093	addiction module antidote protein HigA
CXX03_RS01845	COG2217	Heavy metal translocating P-type atpase
CXX03_RS01855	COG0531	amino acid
CXX03_RS01860	COG0789	Transcriptional regulator
CXX03_RS01865	COG1585	Membrane protein implicated in regulation of membrane protease activity
CXX03_RS01870	COG0330	HflC and HflK could
CXX03_RS01875	COG4619	ABC transporter
CXX03_RS01880	COG0390	transport system, permease component
CXX03_RS01885	COG3118	belongs to the thioredoxin family
CXX03_RS01890	COG0300	oxidoreductase activity
CXX03_RS01895	COG2755	lipolytic protein G-D-S-L family
CXX03_RS01900	COG4181	ATPase activity
CXX03_RS01930	COG0583	DNA-binding transcription factor activity
CXX03_RS01940	COG1414	Transcriptional regulator
CXX03_RS01945	COG3960	tartronate-semialdehyde synthase activity
CXX03_RS01950	COG3622	Belongs to the hyi family
CXX03_RS01955	COG2084	Dehydrogenase
CXX03_RS01960	COG1953	Uracil, thiamine, allantoin
CXX03_RS01970	COG2233	PERMEase
CXX03_RS01975	COG1929	Belongs to the glycerate kinase type-1 family
CXX03_RS01980	COG3257	ureidoglycine aminohydrolase activity
CXX03_RS01985	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CXX03_RS01990	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CXX03_RS01995	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CXX03_RS02000	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CXX03_RS02010	COG0549	Belongs to the carbamate kinase family
CXX03_RS02015	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CXX03_RS02020	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CXX03_RS02030	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CXX03_RS02040	COG1988	membrane-bound metal-dependent
CXX03_RS02045	COG2501	S4 domain
CXX03_RS02055	COG3539	Fimbrial protein
CXX03_RS02060	COG3121	Chaperone
CXX03_RS02065	COG3188	usher protein
CXX03_RS02070	COG3539	Fimbrial protein
CXX03_RS02075	COG3539	Fimbrial protein
CXX03_RS02080	COG2197	response regulator
CXX03_RS02090	COG2207	Transcriptional regulator
CXX03_RS02100	COG4783	chaperone-mediated protein folding
CXX03_RS02105	COG1215	transferase activity, transferring glycosyl groups
CXX03_RS02145	COG4104	PAAR repeat-containing protein
CXX03_RS02145	COG3209	COG3209 Rhs family protein
CXX03_RS02155	COG3501	Rhs element vgr protein
CXX03_RS02160	COG5002	protein histidine kinase activity
CXX03_RS02165	COG0745	RESPONSE REGULATOR receiver
CXX03_RS02170	COG1538	Outer membrane efflux protein
CXX03_RS02175	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CXX03_RS02180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CXX03_RS02185	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CXX03_RS02190	COG1113	amino acid transport
CXX03_RS02195	COG0668	transmembrane transport
CXX03_RS02200	COG0778	Nitroreductase
CXX03_RS02205	COG2315	Protein conserved in bacteria
CXX03_RS02240	COG2977	Belongs to the P-Pant transferase superfamily
CXX03_RS02245	COG4771	TonB-dependent receptor
CXX03_RS02250	COG2382	esterase
CXX03_RS02255	COG3251	PFAM MbtH domain protein
CXX03_RS02260	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CXX03_RS02260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXX03_RS02265	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CXX03_RS02270	COG1120	ATPase activity
CXX03_RS02275	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CXX03_RS02280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CXX03_RS02290	COG4592	Periplasmic binding protein
CXX03_RS02295	COG1169	isochorismate synthase
CXX03_RS02300	COG1021	2,3-dihydroxybenzoate-AMP ligase
CXX03_RS02305	COG1535	isochorismatase
CXX03_RS02305	COG3433	isochorismatase activity
CXX03_RS02310	COG1028	Short-chain dehydrogenase reductase Sdr
CXX03_RS02315	COG2050	protein possibly involved in aromatic compounds catabolism
CXX03_RS02320	COG1966	Carbon starvation protein
CXX03_RS02325	COG2879	small protein
CXX03_RS02330	COG0371	Dehydrogenase
CXX03_RS02335	COG0436	Aminotransferase
CXX03_RS02340	COG1475	DNA binding
CXX03_RS02345	COG3969	phosphoadenosine phosphosulfate
CXX03_RS02350	COG0583	DNA-binding transcription factor activity
CXX03_RS02355	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CXX03_RS02360	COG0450	alkyl hydroperoxide reductase
CXX03_RS02365	COG3634	alkyl hydroperoxide reductase activity
CXX03_RS02370	COG0589	response to stress
CXX03_RS02375	COG1063	alcohol dehydrogenase
CXX03_RS02380	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CXX03_RS02385	COG3719	Belongs to the RNase T2 family
CXX03_RS02390	COG0471	metal ion transport
CXX03_RS02405	COG3051	citrate lyase alpha subunit
CXX03_RS02410	COG2301	Belongs to the HpcH HpaI aldolase family
CXX03_RS02420	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
CXX03_RS02425	COG3290	protein histidine kinase activity
CXX03_RS02430	COG4565	transcriptional regulatory protein
CXX03_RS02435	COG3069	C4-dicarboxylate transmembrane transporter activity
CXX03_RS02455	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CXX03_RS02460	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CXX03_RS02470	COG0583	DNA-binding transcription factor activity
CXX03_RS02485	COG1686	Belongs to the peptidase S11 family
CXX03_RS02490	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CXX03_RS02495	COG0772	Belongs to the SEDS family
CXX03_RS02500	COG0768	penicillin binding
CXX03_RS02510	COG0799	negative regulation of ribosome biogenesis
CXX03_RS02515	COG0406	alpha-ribazole phosphatase activity
CXX03_RS02525	COG1466	dna polymerase III delta subunit
CXX03_RS02540	COG2888	peptidyl-tyrosine sulfation
CXX03_RS02545	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CXX03_RS02555	COG2214	Heat shock protein DnaJ domain protein
CXX03_RS02560	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CXX03_RS02570	COG2214	Heat shock protein DnaJ domain protein
CXX03_RS02575	COG0443	Heat shock 70 kDa protein
CXX03_RS02585	COG1126	abc transporter atp-binding protein
CXX03_RS02590	COG0765	amino acid transport
CXX03_RS02595	COG0765	amino acid transport
CXX03_RS02600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXX03_RS02615	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CXX03_RS02620	COG4535	Mg2 and Co2 transporter CorC
CXX03_RS02630	COG1702	phosphate starvation-inducible protein PhoH
CXX03_RS02640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CXX03_RS02680	COG0367	asparagine synthase
CXX03_RS02685	COG0647	UMP catabolic process
CXX03_RS02690	COG1940	carbohydrate kinase activity
CXX03_RS02690	COG1846	Transcriptional regulator
CXX03_RS02695	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CXX03_RS02705	COG2190	(PTS) system
CXX03_RS02705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXX03_RS02705	COG1263	PTS System
CXX03_RS02725	COG0735	belongs to the Fur family
CXX03_RS02735	COG0716	FMN binding
CXX03_RS02745	COG0596	Alpha beta hydrolase
CXX03_RS02750	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CXX03_RS02755	COG0033	Phosphoglucomutase
CXX03_RS02760	COG0531	amino acid
CXX03_RS02765	COG1982	Orn Lys Arg decarboxylase major
CXX03_RS02780	COG0745	RESPONSE REGULATOR receiver
CXX03_RS02785	COG2205	protein histidine kinase activity
CXX03_RS02845	COG3272	Protein of unknown function (DUF1722)
CXX03_RS02850	COG0415	Belongs to the DNA photolyase family
CXX03_RS02860	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CXX03_RS02865	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CXX03_RS02870	COG1984	allophanate hydrolase subunit 2
CXX03_RS02885	COG3180	Ammonia monooxygenase
CXX03_RS02890	COG3539	Fimbrial protein
CXX03_RS02895	COG3121	Chaperone
CXX03_RS02900	COG3188	usher protein
CXX03_RS02905	COG3539	Fimbrial protein
CXX03_RS02910	COG0372	Belongs to the citrate synthase family
CXX03_RS02920	COG2009	succinate dehydrogenase
CXX03_RS02925	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CXX03_RS02930	COG1053	succinate dehydrogenase
CXX03_RS02935	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CXX03_RS02940	COG0567	Dehydrogenase, E1 component
CXX03_RS02945	COG0508	dehydrogenase complex catalyzes the overall conversion of
CXX03_RS02955	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CXX03_RS02960	COG2188	Transcriptional regulator
CXX03_RS02965	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CXX03_RS02965	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CXX03_RS02965	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX03_RS02970	COG0383	alpha-mannosidase activity
CXX03_RS02980	COG1271	oxidase subunit
CXX03_RS02985	COG1294	oxidase, subunit
CXX03_RS02990	COG4890	Cyd operon protein YbgT
CXX03_RS02995	COG3790	cyd operon protein YbgE
CXX03_RS03000	COG0824	Thioesterase
CXX03_RS03005	COG0811	peptide transport
CXX03_RS03010	COG0848	biopolymer transport protein
CXX03_RS03015	COG3064	Membrane
CXX03_RS03025	COG2885	chlorophyll binding
CXX03_RS03030	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CXX03_RS03070	COG3201	nicotinamide mononucleotide transporter
CXX03_RS03075	COG1230	cation diffusion facilitator family transporter
CXX03_RS03085	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CXX03_RS03095	COG2017	converts alpha-aldose to the beta-anomer
CXX03_RS03105	COG1085	galactose-1-phosphate uridylyltransferase
CXX03_RS03110	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CXX03_RS03115	COG1119	ATPase activity
CXX03_RS03120	COG2005	Transcriptional regulator
CXX03_RS03120	COG3585	molybdate ion transport
CXX03_RS03130	COG0725	ABC transporter, periplasmic molybdate-binding protein
CXX03_RS03135	COG4149	molybdate abc transporter
CXX03_RS03145	COG0561	phosphatase activity
CXX03_RS03155	COG0583	DNA-binding transcription factor activity
CXX03_RS03160	COG2828	Protein conserved in bacteria
CXX03_RS03165	COG0471	metal ion transport
CXX03_RS03170	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CXX03_RS03175	COG4677	pectinesterase activity
CXX03_RS03180	COG1881	PFAM PEBP family protein
CXX03_RS03185	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CXX03_RS03200	COG2226	methyltransferase
CXX03_RS03205	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CXX03_RS03215	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CXX03_RS03225	COG0521	Mo-molybdopterin cofactor biosynthetic process
CXX03_RS03235	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CXX03_RS03240	COG0314	molybdopterin synthase activity
CXX03_RS03245	COG0670	Belongs to the BI1 family
CXX03_RS03250	COG0670	Belongs to the BI1 family
CXX03_RS03255	COG0392	lysyltransferase activity
CXX03_RS03260	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CXX03_RS03265	COG3568	Endonuclease Exonuclease Phosphatase
CXX03_RS03275	COG0842	Transport permease protein
CXX03_RS03280	COG0842	Transport permease protein
CXX03_RS03285	COG1131	(ABC) transporter
CXX03_RS03295	COG1309	transcriptional regulator
CXX03_RS03300	COG0513	Belongs to the DEAD box helicase family
CXX03_RS03310	COG3547	Transposase (IS116 IS110 IS902 family)
CXX03_RS03315	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
CXX03_RS03320	COG1199	ATP-dependent helicase activity
CXX03_RS03325	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CXX03_RS03330	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CXX03_RS03340	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CXX03_RS03350	COG4774	siderophore transport
CXX03_RS03365	COG0668	transmembrane transport
CXX03_RS03370	COG1126	abc transporter atp-binding protein
CXX03_RS03375	COG0765	amino acid transport
CXX03_RS03380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXX03_RS03390	COG5006	permease, DMT superfamily
CXX03_RS03400	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CXX03_RS03405	COG2194	sulfuric ester hydrolase activity
CXX03_RS03415	COG1321	iron dependent repressor
CXX03_RS03420	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CXX03_RS03425	COG1376	ErfK ybiS ycfS ynhG family protein
CXX03_RS03430	COG0488	(ABC) transporter
CXX03_RS03440	COG3547	Transposase (IS116 IS110 IS902 family)
CXX03_RS03460	COG0561	phosphatase activity
CXX03_RS03465	COG1882	Formate acetyltransferase
CXX03_RS03470	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CXX03_RS03475	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CXX03_RS03480	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CXX03_RS03485	COG0303	'Molybdopterin
CXX03_RS03490	COG1446	asparaginase
CXX03_RS03515	COG2200	EAL domain
CXX03_RS03520	COG2199	diguanylate cyclase activity
CXX03_RS03535	COG2133	pyrroloquinoline quinone binding
CXX03_RS03540	COG0625	glutathione transferase activity
CXX03_RS03545	COG1686	Belongs to the peptidase S11 family
CXX03_RS03550	COG1349	DNA-binding transcription factor activity
CXX03_RS03555	COG0671	phosphoesterase, PA-phosphatase related
CXX03_RS03560	COG2814	Major facilitator Superfamily
CXX03_RS03575	COG0738	Major facilitator superfamily
CXX03_RS03580	COG3226	Transcriptional regulator
CXX03_RS03595	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CXX03_RS03605	COG0778	Nitroreductase
CXX03_RS03620	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CXX03_RS03625	COG3842	ATPase activity
CXX03_RS03630	COG1176	ABC-type spermidine putrescine transport system, permease component I
CXX03_RS03635	COG1177	transmembrane transport
CXX03_RS03650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXX03_RS03655	COG4160	amino acid transport
CXX03_RS03660	COG4215	(ABC) transporter
CXX03_RS03665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXX03_RS03670	COG1126	abc transporter atp-binding protein
CXX03_RS03685	COG3023	N-Acetylmuramoyl-L-alanine amidase
CXX03_RS03690	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CXX03_RS03695	COG0702	epimerase
CXX03_RS03700	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CXX03_RS03705	COG0028	Belongs to the TPP enzyme family
CXX03_RS03710	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CXX03_RS03720	COG2431	L-lysine efflux transmembrane transporter activity
CXX03_RS03730	COG3593	DNA synthesis involved in DNA repair
CXX03_RS03735	COG2990	Protein conserved in bacteria
CXX03_RS03740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CXX03_RS03745	COG0577	efflux transmembrane transporter activity
CXX03_RS03745	COG1136	(ABC) transporter
CXX03_RS03750	COG1278	Cold shock
CXX03_RS03760	COG0542	response to heat
CXX03_RS03770	COG1518	maintenance of DNA repeat elements
CXX03_RS03775	COG1203	CRISPR-associated helicase, Cas3
CXX03_RS03840	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CXX03_RS03845	COG4988	ABC transporter
CXX03_RS03850	COG0492	ferredoxin-NADP+ reductase activity
CXX03_RS03855	COG1522	sequence-specific DNA binding
CXX03_RS03870	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CXX03_RS03880	COG0243	molybdopterin cofactor binding
CXX03_RS03885	COG0437	4 iron, 4 sulfur cluster binding
CXX03_RS03890	COG3302	dmso reductase anchor subunit
CXX03_RS03895	COG1335	isochorismatase
CXX03_RS03905	COG0531	amino acid
CXX03_RS03910	COG0583	DNA-binding transcription factor activity
CXX03_RS03915	COG2249	NAD(P)H dehydrogenase (quinone) activity
CXX03_RS03920	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CXX03_RS03925	COG1882	Formate acetyltransferase
CXX03_RS03930	COG2116	formate transmembrane transporter activity
CXX03_RS03935	COG1944	ATP diphosphatase activity
CXX03_RS03940	COG2323	membrane
CXX03_RS03955	COG0501	Belongs to the peptidase M48B family
CXX03_RS03965	COG0539	negative regulation of cytoplasmic translation
CXX03_RS03975	COG2333	competence protein COMEC
CXX03_RS03975	COG0658	competence protein
CXX03_RS03980	COG1132	(ABC) transporter
CXX03_RS03990	COG3214	Protein conserved in bacteria
CXX03_RS04005	COG3173	Aminoglycoside phosphotransferase
CXX03_RS04010	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CXX03_RS04015	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CXX03_RS04025	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CXX03_RS04035	COG2989	Protein conserved in bacteria
CXX03_RS04040	COG3108	Peptidase M15
CXX03_RS04045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CXX03_RS04050	COG1448	Aminotransferase
CXX03_RS04070	COG0308	aminopeptidase N
CXX03_RS04080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CXX03_RS04090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CXX03_RS04095	COG0431	NADPH-dependent FMN reductase
CXX03_RS04100	COG3539	Fimbrial protein
CXX03_RS04105	COG3121	Chaperone
CXX03_RS04110	COG3188	usher protein
CXX03_RS04115	COG3539	Fimbrial protein
CXX03_RS04120	COG3539	Fimbrial protein
CXX03_RS04150	COG0488	(ABC) transporter
CXX03_RS04155	COG2995	paraquat-inducible protein a
CXX03_RS04160	COG3008	intermembrane lipid transfer
CXX03_RS04160	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CXX03_RS04165	COG3009	Protein conserved in bacteria
CXX03_RS04170	COG3130	regulation of translation
CXX03_RS04180	COG1067	ATP-dependent peptidase activity
CXX03_RS04200	COG3070	regulator of competence-specific genes
CXX03_RS04205	COG1289	transmembrane transporter activity
CXX03_RS04210	COG3304	Inner membrane component domain
CXX03_RS04215	COG0210	DNA helicase
CXX03_RS04230	COG1832	CoA-binding protein
CXX03_RS04245	COG1254	Belongs to the acylphosphatase family
CXX03_RS04250	COG2920	part of a sulfur-relay system
CXX03_RS04255	COG0670	Belongs to the BI1 family
CXX03_RS04265	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CXX03_RS04270	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CXX03_RS04275	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
CXX03_RS04280	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CXX03_RS04285	COG1999	signal sequence binding
CXX03_RS04290	COG1773	rubredoxin
CXX03_RS04295	COG1271	oxidase subunit
CXX03_RS04300	COG1294	oxidase, subunit
CXX03_RS04315	COG3206	protein involved in exopolysaccharide biosynthesis
CXX03_RS04315	COG0489	protein tyrosine kinase activity
CXX03_RS04320	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CXX03_RS04325	COG1596	polysaccharide export
CXX03_RS04330	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CXX03_RS04350	COG1278	Cold shock
CXX03_RS04355	COG1278	Cold shock
CXX03_RS04375	COG0348	domain, Protein
CXX03_RS04380	COG2205	protein histidine kinase activity
CXX03_RS04380	COG2198	Histidine kinase
CXX03_RS04380	COG0784	Response regulator, receiver
CXX03_RS04385	COG1879	ABC-type sugar transport system periplasmic component
CXX03_RS04390	COG0745	RESPONSE REGULATOR receiver
CXX03_RS04395	COG3005	denitrification pathway
CXX03_RS04440	COG3729	General stress protein
CXX03_RS04445	COG2233	PERMEase
CXX03_RS04480	COG1309	transcriptional regulator
CXX03_RS04485	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CXX03_RS04485	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CXX03_RS04485	COG0506	proline dehydrogenase activity
CXX03_RS04495	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CXX03_RS04505	COG2822	iron ion transport
CXX03_RS04515	COG1702	phosphate starvation-inducible protein PhoH
CXX03_RS04540	COG0582	viral genome integration into host DNA
CXX03_RS04580	COG4983	Phage plasmid primase, P4 family domain protein
CXX03_RS04610	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CXX03_RS04620	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CXX03_RS04625	COG1263	PTS System
CXX03_RS04625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXX03_RS04635	COG1349	DNA-binding transcription factor activity
CXX03_RS04640	COG2721	sulfolactate sulfo-lyase activity
CXX03_RS04645	COG2721	sulfolactate sulfo-lyase activity
CXX03_RS04660	COG0440	acetolactate synthase activity
CXX03_RS04665	COG1349	DNA-binding transcription factor activity
CXX03_RS04670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CXX03_RS04675	COG0738	Major facilitator superfamily
CXX03_RS04690	COG3436	PFAM IS66 Orf2 family protein
CXX03_RS04695	COG4372	Transposase
CXX03_RS04745	COG0583	DNA-binding transcription factor activity
CXX03_RS04755	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CXX03_RS04770	COG0531	amino acid
CXX03_RS04775	COG1982	Orn Lys Arg decarboxylase major
CXX03_RS04780	COG0531	amino acid
CXX03_RS04805	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CXX03_RS04820	COG2990	Protein conserved in bacteria
CXX03_RS04825	COG0297	glycogen (starch) synthase activity
CXX03_RS04830	COG0726	polysaccharide deacetylase
CXX03_RS04845	COG3344	reverse transcriptase
CXX03_RS04855	COG2085	NADP oxidoreductase coenzyme F420-dependent
CXX03_RS04860	COG1120	ATPase activity
CXX03_RS04865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CXX03_RS04870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CXX03_RS04875	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CXX03_RS04880	COG4772	TonB-dependent receptor
CXX03_RS04885	COG3712	iron ion homeostasis
CXX03_RS04890	COG1595	DNA-templated transcription, initiation
CXX03_RS04930	COG4372	Transposase
CXX03_RS04935	COG3436	PFAM IS66 Orf2 family protein
CXX03_RS05025	COG3468	outer membrane autotransporter barrel domain protein
CXX03_RS05030	COG2020	methyltransferase activity
CXX03_RS05060	COG2003	Belongs to the UPF0758 family
CXX03_RS05115	COG3381	protein complex oligomerization
CXX03_RS05125	COG1462	curli production assembly transport component CsgG
CXX03_RS05140	COG2197	response regulator
CXX03_RS05165	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CXX03_RS05170	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CXX03_RS05185	COG2943	transferase activity, transferring hexosyl groups
CXX03_RS05190	COG5645	(Lipo)protein
CXX03_RS05205	COG1560	Kdo2-lipid A biosynthetic process
CXX03_RS05215	COG2353	YceI-like domain
CXX03_RS05220	COG3038	cytochrome b561
CXX03_RS05255	COG2999	glutathione oxidoreductase activity
CXX03_RS05265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CXX03_RS05275	COG0673	inositol 2-dehydrogenase activity
CXX03_RS05280	COG0728	peptidoglycan biosynthetic process
CXX03_RS05285	COG3418	PFAM FlgN family protein
CXX03_RS05290	COG2747	anti-sigma28 factor FlgM
CXX03_RS05295	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
CXX03_RS05300	COG1815	bacterial-type flagellum-dependent cell motility
CXX03_RS05305	COG1558	bacterial-type flagellum-dependent cell motility
CXX03_RS05310	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CXX03_RS05315	COG1749	Flagellar hook protein flgE
CXX03_RS05320	COG4787	bacterial-type flagellum-dependent cell motility
CXX03_RS05325	COG4786	Flagellar basal body rod
CXX03_RS05340	COG3951	Flagellar rod assembly protein muramidase FlgJ
CXX03_RS05340	COG1705	Flagellar rod assembly protein muramidase FlgJ
CXX03_RS05345	COG1256	bacterial-type flagellum assembly
CXX03_RS05350	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CXX03_RS05355	COG1530	ribonuclease E activity
CXX03_RS05365	COG0564	pseudouridine synthase activity
CXX03_RS05370	COG0424	maF-like protein
CXX03_RS05375	COG1399	metal-binding, possibly nucleic acid-binding protein
CXX03_RS05395	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CXX03_RS05400	COG1028	Short-chain dehydrogenase reductase Sdr
CXX03_RS05410	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CXX03_RS05415	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CXX03_RS05420	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CXX03_RS05430	COG0470	DNA polymerase III
CXX03_RS05435	COG0084	hydrolase, TatD family'
CXX03_RS05440	COG1263	PTS System
CXX03_RS05440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXX03_RS05445	COG4773	Receptor
CXX03_RS05450	COG0537	adenosine 5'-monophosphoramidase activity
CXX03_RS05455	COG5633	Lipoprotein
CXX03_RS05460	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
CXX03_RS05480	COG1252	NADH dehydrogenase
CXX03_RS05485	COG3134	Outer membrane lipoprotein
CXX03_RS05490	COG1309	transcriptional regulator
CXX03_RS05500	COG1388	LysM domain
CXX03_RS05500	COG1376	ErfK ybiS ycfS ynhG family protein
CXX03_RS05505	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CXX03_RS05510	COG4763	Acyl-transferase
CXX03_RS05515	COG4591	ABC-type transport system involved in lipoprotein release permease component
CXX03_RS05520	COG1136	(ABC) transporter
CXX03_RS05525	COG4591	ABC-type transport system involved in lipoprotein release permease component
CXX03_RS05535	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CXX03_RS05540	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CXX03_RS05550	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CXX03_RS05555	COG1177	transmembrane transport
CXX03_RS05560	COG0582	viral genome integration into host DNA
CXX03_RS05570	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CXX03_RS05615	COG1846	Transcriptional regulator
CXX03_RS05620	COG1484	DNA-dependent DNA replication
CXX03_RS05660	COG1403	HNH endonuclease
CXX03_RS05665	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CXX03_RS05745	COG4220	transposase activity
CXX03_RS05850	COG5301	cellulose 1,4-beta-cellobiosidase activity
CXX03_RS05850	COG5301	cellulose 1,4-beta-cellobiosidase activity
CXX03_RS05870	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CXX03_RS05885	COG0500	methyltransferase
CXX03_RS05900	COG3842	ATPase activity
CXX03_RS05910	COG2850	peptidyl-arginine hydroxylation
CXX03_RS05915	COG2205	protein histidine kinase activity
CXX03_RS05925	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CXX03_RS05945	COG1187	pseudouridine synthase activity
CXX03_RS05950	COG0538	isocitrate dehydrogenase activity
CXX03_RS05965	COG5562	phage envelope protein
CXX03_RS05970	COG0789	Transcriptional regulator
CXX03_RS05975	COG2200	EAL domain
CXX03_RS06000	COG2200	EAL domain
CXX03_RS06060	COG2894	cell division
CXX03_RS06085	COG0179	Fumarylacetoacetate (FAA) hydrolase
CXX03_RS06100	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CXX03_RS06105	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CXX03_RS06125	COG2719	SpoVR family
CXX03_RS06135	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CXX03_RS06145	COG1619	proteins homologs of microcin C7 resistance protein MccF
CXX03_RS06155	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CXX03_RS06175	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CXX03_RS06175	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX03_RS06175	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CXX03_RS06180	COG1461	Dihydroxyacetone kinase
CXX03_RS06185	COG2376	Dihydroxyacetone kinase
CXX03_RS06190	COG3284	Transcriptional regulator
CXX03_RS06195	COG3468	outer membrane autotransporter barrel domain protein
CXX03_RS06200	COG0012	GTP binding
CXX03_RS06215	COG0659	secondary active sulfate transmembrane transporter activity
CXX03_RS06220	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CXX03_RS06245	COG2890	protein-(glutamine-N5) methyltransferase activity
CXX03_RS06250	COG3094	Invasion gene expression up-regulator, SirB
CXX03_RS06255	COG2912	Transglutaminase-like superfamily
CXX03_RS06275	COG0387	Pfam Sodium calcium exchanger
CXX03_RS06280	COG4572	Cation transport regulator
CXX03_RS06285	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CXX03_RS06290	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CXX03_RS06295	COG4932	domain protein
CXX03_RS06300	COG2197	response regulator
CXX03_RS06305	COG3850	Histidine kinase
CXX03_RS06310	COG2223	nitrite transmembrane transporter activity
CXX03_RS06315	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CXX03_RS06320	COG1140	nitrate reductase beta subunit
CXX03_RS06325	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CXX03_RS06330	COG2181	nitrate reductase activity
CXX03_RS06350	COG0788	formyltetrahydrofolate deformylase activity
CXX03_RS06360	COG1752	Esterase of the alpha-beta hydrolase superfamily
CXX03_RS06365	COG0745	RESPONSE REGULATOR receiver
CXX03_RS06370	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CXX03_RS06380	COG1435	thymidine kinase activity
CXX03_RS06390	COG1454	alcohol dehydrogenase
CXX03_RS06390	COG1012	belongs to the aldehyde dehydrogenase family
CXX03_RS06395	COG2095	MarC family integral membrane protein
CXX03_RS06400	COG4166	transmembrane transport
CXX03_RS06405	COG0601	transmembrane transport
CXX03_RS06410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CXX03_RS06415	COG0444	Belongs to the ABC transporter superfamily
CXX03_RS06420	COG4608	Belongs to the ABC transporter superfamily
CXX03_RS06440	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CXX03_RS06445	COG2350	Protein conserved in bacteria
CXX03_RS06455	COG1607	acyl-coa hydrolase
CXX03_RS06475	COG3047	cAMP biosynthetic process
CXX03_RS06480	COG3685	Protein conserved in bacteria
CXX03_RS06485	COG3685	Protein conserved in bacteria
CXX03_RS06490	COG3729	General stress protein
CXX03_RS06505	COG0135	phosphoribosylanthranilate isomerase activity
CXX03_RS06505	COG0134	indole-3-glycerol-phosphate synthase activity
CXX03_RS06510	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CXX03_RS06510	COG0512	Glutamine amidotransferase of anthranilate synthase
CXX03_RS06515	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CXX03_RS06525	COG0613	PHP domain protein
CXX03_RS06530	COG0009	L-threonylcarbamoyladenylate synthase
CXX03_RS06535	COG1187	pseudouridine synthase activity
CXX03_RS06540	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CXX03_RS06545	COG1028	Short-chain dehydrogenase reductase Sdr
CXX03_RS06550	COG0616	signal peptide processing
CXX03_RS06560	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CXX03_RS06565	COG0583	DNA-binding transcription factor activity
CXX03_RS06585	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CXX03_RS06595	COG0671	phosphoesterase, PA-phosphatase related
CXX03_RS06600	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CXX03_RS06605	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CXX03_RS06615	COG0023	Translation Initiation Factor
CXX03_RS06625	COG1349	DNA-binding transcription factor activity
CXX03_RS06635	COG5001	Diguanylate cyclase
CXX03_RS06650	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CXX03_RS06650	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CXX03_RS06655	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CXX03_RS06660	COG2852	Protein conserved in bacteria
CXX03_RS06665	COG4172	Belongs to the ABC transporter superfamily
CXX03_RS06670	COG4172	Belongs to the ABC transporter superfamily
CXX03_RS06675	COG4171	peptide transport system, permease
CXX03_RS06680	COG4168	peptide transport system, permease
CXX03_RS06685	COG4166	transmembrane transport
CXX03_RS06695	COG0531	amino acid
CXX03_RS06705	COG0174	glutamine synthetase
CXX03_RS06710	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CXX03_RS06715	COG1917	Cupin 2, conserved barrel domain protein
CXX03_RS06715	COG1396	sequence-specific DNA binding
CXX03_RS06720	COG1012	belongs to the aldehyde dehydrogenase family
CXX03_RS06725	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CXX03_RS06730	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CXX03_RS06735	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CXX03_RS06740	COG1842	Phage shock protein A
CXX03_RS06750	COG1983	PspC domain protein
CXX03_RS06760	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CXX03_RS06770	COG1653	transport
CXX03_RS06775	COG1175	transmembrane transport
CXX03_RS06780	COG0395	ABC-type sugar transport system, permease component
CXX03_RS06785	COG1063	alcohol dehydrogenase
CXX03_RS06790	COG1082	Xylose isomerase domain protein TIM barrel
CXX03_RS06795	COG0673	inositol 2-dehydrogenase activity
CXX03_RS06800	COG1554	hydrolase, family 65, central catalytic
CXX03_RS06805	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CXX03_RS06810	COG3842	ATPase activity
CXX03_RS06820	COG1609	Transcriptional regulator
CXX03_RS06825	COG3106	COG3106 Predicted ATPase
CXX03_RS06835	COG3283	Transcriptional regulator of aromatic amino acids metabolism
CXX03_RS06840	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CXX03_RS06845	COG4948	Mandelate Racemase Muconate Lactonizing
CXX03_RS06850	COG2866	Carboxypeptidase
CXX03_RS06865	COG1073	alpha beta
CXX03_RS06870	COG0583	DNA-binding transcription factor activity
CXX03_RS06875	COG4166	transmembrane transport
CXX03_RS06880	COG0668	transmembrane transport
CXX03_RS06885	COG3182	Iron-regulated membrane protein
CXX03_RS06890	COG0589	response to stress
CXX03_RS06895	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CXX03_RS06900	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CXX03_RS06905	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CXX03_RS06910	COG1473	amidohydrolase
CXX03_RS06915	COG1473	amidohydrolase
CXX03_RS06920	COG0583	DNA-binding transcription factor activity
CXX03_RS06925	COG2840	Smr protein MutS2
CXX03_RS06930	COG3706	GGDEF domain
CXX03_RS06940	COG0513	Belongs to the DEAD box helicase family
CXX03_RS06950	COG0589	response to stress
CXX03_RS06955	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CXX03_RS06960	COG0674	pyruvate-flavodoxin oxidoreductase activity
CXX03_RS06960	COG1013	pyruvate-flavodoxin oxidoreductase activity
CXX03_RS06960	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CXX03_RS06960	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CXX03_RS06965	COG3042	response to heat
CXX03_RS06970	COG3187	Heat shock protein
CXX03_RS06975	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CXX03_RS06980	COG2911	Protein conserved in bacteria
CXX03_RS06990	COG3784	Protein of unknown function (DUF1318)
CXX03_RS06995	COG2207	Transcriptional regulator
CXX03_RS07000	COG1012	belongs to the aldehyde dehydrogenase family
CXX03_RS07005	COG3733	amine oxidase
CXX03_RS07010	COG1012	belongs to the aldehyde dehydrogenase family
CXX03_RS07010	COG2030	dehydratase
CXX03_RS07015	COG3396	Phenylacetate-CoA oxygenase
CXX03_RS07020	COG3460	Phenylacetate-CoA oxygenase
CXX03_RS07025	COG3396	Phenylacetate-CoA oxygenase
CXX03_RS07030	COG2151	metal-sulfur cluster biosynthetic enzyme
CXX03_RS07035	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CXX03_RS07040	COG1024	Enoyl-CoA hydratase
CXX03_RS07045	COG1024	Enoyl-CoA hydratase
CXX03_RS07050	COG1250	3-hydroxyacyl-CoA dehydrogenase
CXX03_RS07055	COG2050	protein possibly involved in aromatic compounds catabolism
CXX03_RS07060	COG0183	Belongs to the thiolase family
CXX03_RS07065	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CXX03_RS07070	COG3327	negative regulation of DNA-templated transcription, initiation
CXX03_RS07075	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CXX03_RS07080	COG0667	Aldo Keto reductase
CXX03_RS07090	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CXX03_RS07095	COG4589	Belongs to the CDS family
CXX03_RS07100	COG2267	carboxylic ester hydrolase activity
CXX03_RS07105	COG0671	phosphoesterase, PA-phosphatase related
CXX03_RS07105	COG2453	phosphatase
CXX03_RS07115	COG1643	Atp-dependent helicase
CXX03_RS07120	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CXX03_RS07125	COG1012	belongs to the aldehyde dehydrogenase family
CXX03_RS07130	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CXX03_RS07135	COG3038	cytochrome b561
CXX03_RS07155	COG0840	transmembrane signaling receptor activity
CXX03_RS07160	COG0583	DNA-binding transcription factor activity
CXX03_RS07165	COG5383	Protein conserved in bacteria
CXX03_RS07175	COG2841	Protein conserved in bacteria
CXX03_RS07185	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CXX03_RS07190	COG1275	C4-dicarboxylate transporter malic acid transport protein
CXX03_RS07195	COG0500	methyltransferase
CXX03_RS07210	COG0675	Transposase, IS605 OrfB family
CXX03_RS07215	COG3135	benzoate transporter
CXX03_RS07220	COG1396	sequence-specific DNA binding
CXX03_RS07225	COG0826	peptidase U32
CXX03_RS07235	COG1724	mRNA binding
CXX03_RS07240	COG1598	PFAM Uncharacterised protein family UPF0150
CXX03_RS07245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CXX03_RS07250	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CXX03_RS07255	COG3842	ATPase activity
CXX03_RS07260	COG1176	ABC-type spermidine putrescine transport system, permease component I
CXX03_RS07265	COG1177	transmembrane transport
CXX03_RS07290	COG3238	Protein conserved in bacteria
CXX03_RS07295	COG1247	-acetyltransferase
CXX03_RS07300	COG2130	NADP-dependent
CXX03_RS07305	COG1802	Transcriptional regulator
CXX03_RS07310	COG4772	TonB-dependent receptor
CXX03_RS07315	COG3391	amine dehydrogenase activity
CXX03_RS07320	COG1113	amino acid transport
CXX03_RS07325	COG0625	glutathione transferase activity
CXX03_RS07370	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CXX03_RS07375	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CXX03_RS07380	COG0384	phenazine biosynthesis protein PhzF
CXX03_RS07385	COG2181	nitrate reductase activity
CXX03_RS07390	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CXX03_RS07395	COG1140	nitrate reductase beta subunit
CXX03_RS07400	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CXX03_RS07405	COG2223	nitrite transmembrane transporter activity
CXX03_RS07410	COG4886	Leucine-rich repeat (LRR) protein
CXX03_RS07415	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CXX03_RS07420	COG0697	spore germination
CXX03_RS07425	COG0243	molybdopterin cofactor binding
CXX03_RS07425	COG3383	formate dehydrogenase (NAD+) activity
CXX03_RS07430	COG3383	formate dehydrogenase (NAD+) activity
CXX03_RS07430	COG0243	molybdopterin cofactor binding
CXX03_RS07435	COG0437	4 iron, 4 sulfur cluster binding
CXX03_RS07440	COG2864	formate dehydrogenase
CXX03_RS07445	COG3093	addiction module antidote protein HigA
CXX03_RS07450	COG1064	alcohol dehydrogenase
CXX03_RS07470	COG1764	response to oxidative stress
CXX03_RS07475	COG1028	Short-chain dehydrogenase reductase Sdr
CXX03_RS07485	COG1250	3-hydroxyacyl-CoA dehydrogenase
CXX03_RS07495	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CXX03_RS07500	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CXX03_RS07510	COG4608	Belongs to the ABC transporter superfamily
CXX03_RS07515	COG0444	Belongs to the ABC transporter superfamily
CXX03_RS07520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CXX03_RS07525	COG0601	transmembrane transport
CXX03_RS07530	COG0747	negative chemotaxis
CXX03_RS07535	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CXX03_RS07540	COG2202	Pas domain
CXX03_RS07540	COG2200	EAL domain
CXX03_RS07540	COG2199	diguanylate cyclase activity
CXX03_RS07550	COG1649	PFAM Uncharacterised BCR, COG1649
CXX03_RS07555	COG0531	amino acid
CXX03_RS07560	COG0076	glutamate decarboxylase activity
CXX03_RS07565	COG0612	Peptidase, M16
CXX03_RS07570	COG4771	TonB-dependent receptor
CXX03_RS07575	COG4178	(ABC) transporter
CXX03_RS07585	COG0641	radical SAM
CXX03_RS07590	COG3119	arylsulfatase activity
CXX03_RS07595	COG2207	Transcriptional regulator
CXX03_RS07605	COG0243	molybdopterin cofactor binding
CXX03_RS07610	COG3539	Fimbrial protein
CXX03_RS07615	COG3539	Fimbrial protein
CXX03_RS07620	COG3539	Fimbrial protein
CXX03_RS07625	COG3188	usher protein
CXX03_RS07635	COG3539	Fimbrial protein
CXX03_RS07895	COG3550	peptidyl-serine autophosphorylation
CXX03_RS07895	COG3550	peptidyl-serine autophosphorylation
CXX03_RS07900	COG1396	sequence-specific DNA binding
CXX03_RS07905	COG3210	domain, Protein
CXX03_RS07905	COG2911	Protein conserved in bacteria
CXX03_RS07915	COG2911	Protein conserved in bacteria
CXX03_RS07915	COG3210	domain, Protein
CXX03_RS07965	COG3781	membrane
CXX03_RS07975	COG2199	diguanylate cyclase activity
CXX03_RS07985	COG2066	Belongs to the glutaminase family
CXX03_RS07990	COG1012	belongs to the aldehyde dehydrogenase family
CXX03_RS07995	COG0583	DNA-binding transcription factor activity
CXX03_RS08015	COG1846	Transcriptional regulator
CXX03_RS08020	COG4977	sequence-specific DNA binding
CXX03_RS08030	COG2723	6-phospho-beta-galactosidase activity
CXX03_RS08040	COG1447	Phosphotransferase system cellobiose-specific component IIA
CXX03_RS08045	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CXX03_RS08055	COG2188	Transcriptional regulator
CXX03_RS08060	COG0697	spore germination
CXX03_RS08065	COG2814	Major facilitator Superfamily
CXX03_RS08075	COG3706	GGDEF domain
CXX03_RS08080	COG3111	PFAM Bacterial OB fold (BOF) protein
CXX03_RS08085	COG1546	Belongs to the CinA family
CXX03_RS08090	COG0339	signal peptide processing
CXX03_RS08095	COG4221	oxidoreductase activity
CXX03_RS08100	COG1802	Transcriptional regulator
CXX03_RS08110	COG0246	Mannitol dehydrogenase
CXX03_RS08115	COG0477	Major facilitator Superfamily
CXX03_RS08130	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CXX03_RS08145	COG3272	Protein of unknown function (DUF1722)
CXX03_RS08160	COG1403	HNH endonuclease
CXX03_RS08240	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CXX03_RS08260	COG0582	viral genome integration into host DNA
CXX03_RS08270	COG1063	alcohol dehydrogenase
CXX03_RS08275	COG4948	Mandelate Racemase Muconate Lactonizing
CXX03_RS08290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CXX03_RS08305	COG0243	molybdopterin cofactor binding
CXX03_RS08310	COG0243	molybdopterin cofactor binding
CXX03_RS08315	COG0437	4 iron, 4 sulfur cluster binding
CXX03_RS08320	COG3302	dmso reductase anchor subunit
CXX03_RS08325	COG3381	protein complex oligomerization
CXX03_RS08335	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CXX03_RS08340	COG1940	carbohydrate kinase activity
CXX03_RS08345	COG0583	DNA-binding transcription factor activity
CXX03_RS08350	COG2814	Major facilitator Superfamily
CXX03_RS08365	COG3591	Belongs to the peptidase S1B family
CXX03_RS08385	COG0628	permease
CXX03_RS08390	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CXX03_RS08395	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CXX03_RS08405	COG0531	amino acid
CXX03_RS08415	COG3136	membrane protein required for alginate biosynthesis
CXX03_RS08420	COG0745	RESPONSE REGULATOR receiver
CXX03_RS08425	COG2205	protein histidine kinase activity
CXX03_RS08435	COG0114	fumarate hydratase activity
CXX03_RS08440	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CXX03_RS08440	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CXX03_RS08445	COG1482	cell wall glycoprotein biosynthetic process
CXX03_RS08450	COG5339	Protein conserved in bacteria
CXX03_RS08465	COG3250	beta-galactosidase activity
CXX03_RS08470	COG1309	transcriptional regulator
CXX03_RS08475	COG1028	Short-chain dehydrogenase reductase Sdr
CXX03_RS08480	COG1609	Transcriptional regulator
CXX03_RS08485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXX03_RS08485	COG1263	PTS System
CXX03_RS08490	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CXX03_RS08500	COG0673	inositol 2-dehydrogenase activity
CXX03_RS08540	COG4659	FMN binding
CXX03_RS08550	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CXX03_RS08555	COG3104	oligopeptide transport
CXX03_RS08560	COG0625	glutathione transferase activity
CXX03_RS08565	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CXX03_RS08580	COG3895	Periplasmic Protein
CXX03_RS08590	COG3133	Outer membrane lipoprotein
CXX03_RS08605	COG1566	PFAM secretion protein HlyD family protein
CXX03_RS08610	COG1289	transmembrane transporter activity
CXX03_RS08615	COG2032	superoxide dismutase activity
CXX03_RS08620	COG4989	oxidoreductase activity
CXX03_RS08625	COG3313	Fe-S protein
CXX03_RS08630	COG1309	transcriptional regulator
CXX03_RS08635	COG1902	pentaerythritol trinitrate reductase activity
CXX03_RS08640	COG0346	lactoylglutathione lyase activity
CXX03_RS08650	COG1201	RNA secondary structure unwinding
CXX03_RS08655	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CXX03_RS08660	COG0791	NLP P60 protein
CXX03_RS08665	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CXX03_RS08670	COG2814	Major facilitator Superfamily
CXX03_RS08685	COG0583	DNA-binding transcription factor activity
CXX03_RS08690	COG2814	Major facilitator Superfamily
CXX03_RS08695	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CXX03_RS08700	COG0307	riboflavin synthase, alpha
CXX03_RS08710	COG3468	outer membrane autotransporter barrel domain protein
CXX03_RS08730	COG4529	Protein conserved in bacteria
CXX03_RS08740	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
CXX03_RS08745	COG0437	4 iron, 4 sulfur cluster binding
CXX03_RS08755	COG2414	aldehyde ferredoxin oxidoreductase
CXX03_RS08760	COG0437	4 iron, 4 sulfur cluster binding
CXX03_RS08770	COG0469	pyruvate kinase activity
CXX03_RS08775	COG4238	major outer membrane lipoprotein
CXX03_RS08780	COG1376	ErfK ybiS ycfS ynhG family protein
CXX03_RS08795	COG0719	Fe-S assembly protein
CXX03_RS08800	COG0396	ATPase activity
CXX03_RS08805	COG0719	Fe-S assembly protein
CXX03_RS08810	COG0316	Belongs to the HesB IscA family
CXX03_RS08820	COG2050	protein possibly involved in aromatic compounds catabolism
CXX03_RS08825	COG0277	FAD linked oxidase domain protein
CXX03_RS08825	COG0247	lactate metabolic process
CXX03_RS08830	COG0628	permease
CXX03_RS08845	COG0738	Major facilitator superfamily
CXX03_RS08850	COG2271	Major facilitator Superfamily
CXX03_RS08880	COG0574	Belongs to the PEP-utilizing enzyme family
CXX03_RS08880	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CXX03_RS08890	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CXX03_RS08895	COG4256	Hemin uptake protein
CXX03_RS08905	COG2200	EAL domain
CXX03_RS08910	COG0791	NLP P60 protein
CXX03_RS08920	COG0386	Belongs to the glutathione peroxidase family
CXX03_RS08980	COG3137	Salt-induced outer membrane protein
CXX03_RS08985	COG1105	Belongs to the carbohydrate kinase PfkB family
CXX03_RS08995	COG3001	Fructosamine kinase
CXX03_RS09005	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CXX03_RS09010	COG1988	membrane-bound metal-dependent
CXX03_RS09015	COG1823	symporter activity
CXX03_RS09040	COG0753	catalase activity
CXX03_RS09050	COG1486	melibiose metabolic process
CXX03_RS09055	COG1917	Cupin 2, conserved barrel domain protein
CXX03_RS09055	COG2169	Transcriptional regulator
CXX03_RS09060	COG1447	Phosphotransferase system cellobiose-specific component IIA
CXX03_RS09065	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CXX03_RS09070	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CXX03_RS09080	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CXX03_RS09090	COG0322	excinuclease ABC activity
CXX03_RS09100	COG3678	ATP-independent chaperone mediated protein folding
CXX03_RS09130	COG0708	Exodeoxyribonuclease III
CXX03_RS09135	COG0398	Pfam SNARE associated Golgi protein
CXX03_RS09145	COG0398	Pfam SNARE associated Golgi protein
CXX03_RS09150	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CXX03_RS09155	COG4134	Bacterial extracellular solute-binding protein
CXX03_RS09160	COG4135	transport system, permease component
CXX03_RS09165	COG4136	ATPase activity
CXX03_RS09170	COG2897	thiosulfate sulfurtransferase activity
CXX03_RS09175	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CXX03_RS09180	COG0494	nUDIX hydrolase
CXX03_RS09190	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CXX03_RS09200	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CXX03_RS09210	COG0778	Nitroreductase
CXX03_RS09215	COG0616	signal peptide processing
CXX03_RS09220	COG0252	asparaginase activity
CXX03_RS09225	COG1335	isochorismatase
CXX03_RS09230	COG3139	Protein of unknown function (DUF1315)
CXX03_RS09240	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CXX03_RS09245	COG0676	glucose-6-phosphate 1-epimerase activity
CXX03_RS09250	COG0656	L-ascorbic acid biosynthetic process
CXX03_RS09255	COG3713	MltA-interacting MipA family protein
CXX03_RS09260	COG2766	serine protein kinase
CXX03_RS09275	COG2199	diguanylate cyclase activity
CXX03_RS09280	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CXX03_RS09295	COG2207	Transcriptional regulator
CXX03_RS09300	COG2807	transmembrane transport
CXX03_RS09305	COG3189	MarR family transcriptional regulator
CXX03_RS09310	COG3042	response to heat
CXX03_RS09315	COG2203	Gaf domain
CXX03_RS09315	COG2199	diguanylate cyclase activity
CXX03_RS09330	COG2261	transglycosylase associated protein
CXX03_RS09335	COG0675	Transposase, IS605 OrfB family
CXX03_RS09350	COG3615	Tellurite resistance protein tehB
CXX03_RS09360	COG0583	DNA-binding transcription factor activity
CXX03_RS09365	COG0473	3-isopropylmalate dehydrogenase activity
CXX03_RS09370	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CXX03_RS09375	COG4638	Rieske (2fe-2S)
CXX03_RS09380	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CXX03_RS09385	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CXX03_RS09390	COG0318	PFAM AMP-dependent synthetase and ligase
CXX03_RS09395	COG3065	identical protein binding
CXX03_RS09400	COG1214	PFAM Peptidase M22, glycoprotease
CXX03_RS09405	COG1199	ATP-dependent helicase activity
CXX03_RS09410	COG0251	oxidation-reduction process
CXX03_RS09425	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CXX03_RS09435	COG1760	l-serine dehydratase
CXX03_RS09440	COG2200	EAL domain
CXX03_RS09445	COG1253	flavin adenine dinucleotide binding
CXX03_RS09450	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX03_RS09450	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXX03_RS09455	COG3715	PTS system
CXX03_RS09460	COG3716	PTS system mannose fructose sorbose family IID component
CXX03_RS09475	COG2226	methyltransferase
CXX03_RS09505	COG1414	Transcriptional regulator
CXX03_RS09510	COG2814	Major facilitator Superfamily
CXX03_RS09520	COG0793	Belongs to the peptidase S41A family
CXX03_RS09530	COG1956	GAF domain-containing protein
CXX03_RS09535	COG2995	paraquat-inducible protein a
CXX03_RS09540	COG3008	intermembrane lipid transfer
CXX03_RS09560	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CXX03_RS09570	COG1276	copper resistance
CXX03_RS09575	COG2372	response to copper ion
CXX03_RS09585	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CXX03_RS09590	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CXX03_RS09595	COG1770	oligopeptidase
CXX03_RS09600	COG2979	Protein of unknown function (DUF533)
CXX03_RS09610	COG3141	response to X-ray
CXX03_RS09620	COG0800	Aldolase
CXX03_RS09625	COG0129	dihydroxy-acid dehydratase activity
CXX03_RS09630	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CXX03_RS09635	COG1737	Transcriptional regulator
CXX03_RS09640	COG0469	pyruvate kinase activity
CXX03_RS09645	COG1560	Kdo2-lipid A biosynthetic process
CXX03_RS09650	COG0739	heme binding
CXX03_RS09655	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CXX03_RS09665	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CXX03_RS09695	COG0217	transcriptional regulatory protein
CXX03_RS09700	COG0494	nUDIX hydrolase
CXX03_RS09710	COG1335	isochorismatase
CXX03_RS09715	COG1801	Protein of unknown function DUF72
CXX03_RS09720	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CXX03_RS09815	COG1801	Protein of unknown function DUF72
CXX03_RS09820	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CXX03_RS09835	COG3547	Transposase (IS116 IS110 IS902 family)
CXX03_RS09845	COG0243	molybdopterin cofactor binding
CXX03_RS09850	COG3005	denitrification pathway
CXX03_RS09860	COG3102	Protein conserved in bacteria
CXX03_RS09870	COG3755	Protein conserved in bacteria
CXX03_RS09880	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CXX03_RS09885	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CXX03_RS09890	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CXX03_RS09895	COG0745	RESPONSE REGULATOR receiver
CXX03_RS09900	COG2201	protein-glutamate methylesterase activity
CXX03_RS09905	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CXX03_RS09910	COG0840	transmembrane signaling receptor activity
CXX03_RS09915	COG0840	transmembrane signaling receptor activity
CXX03_RS09920	COG0835	chemotaxis
CXX03_RS09925	COG0643	Histidine kinase
CXX03_RS09925	COG2198	Histidine kinase
CXX03_RS09930	COG1360	Flagellar Motor Protein
CXX03_RS09935	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CXX03_RS09950	COG0589	response to stress
CXX03_RS09960	COG1877	trehalose-phosphatase activity
CXX03_RS09965	COG1172	Belongs to the binding-protein-dependent transport system permease family
CXX03_RS09970	COG1129	ABC transporter
CXX03_RS09975	COG1879	ABC-type sugar transport system periplasmic component
CXX03_RS09980	COG1528	Iron-storage protein
CXX03_RS10000	COG1528	Iron-storage protein
CXX03_RS10010	COG0814	amino acid
CXX03_RS10015	COG3012	SEC-C Motif Domain Protein
CXX03_RS10015	COG3318	Belongs to the UPF0149 family
CXX03_RS10045	COG2197	response regulator
CXX03_RS10060	COG2197	response regulator
CXX03_RS10065	COG1126	abc transporter atp-binding protein
CXX03_RS10070	COG0765	amino acid transport
CXX03_RS10080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXX03_RS10090	COG1191	sigma factor activity
CXX03_RS10100	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CXX03_RS10105	COG1516	flagellar protein fliS
CXX03_RS10115	COG0366	Alpha amylase catalytic
CXX03_RS10125	COG2391	methyltransferase activity
CXX03_RS10130	COG0425	Belongs to the sulfur carrier protein TusA family
CXX03_RS10135	COG2135	peptidase activity
CXX03_RS10140	COG0675	Transposase, IS605 OrfB family
CXX03_RS10150	COG2207	Transcriptional regulator
CXX03_RS10155	COG1881	PFAM PEBP family protein
CXX03_RS10160	COG2076	Multidrug Resistance protein
CXX03_RS10175	COG1766	The M ring may be actively involved in energy transduction
CXX03_RS10180	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CXX03_RS10185	COG1317	bacterial-type flagellum organization
CXX03_RS10190	COG1157	protein secretion by the type III secretion system
CXX03_RS10195	COG2882	bacterial-type flagellum organization
CXX03_RS10200	COG3144	bacterial-type flagellum assembly
CXX03_RS10205	COG1580	Controls the rotational direction of flagella during chemotaxis
CXX03_RS10210	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CXX03_RS10215	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CXX03_RS10220	COG3190	flagellar
CXX03_RS10225	COG1338	Plays a role in the flagellum-specific transport system
CXX03_RS10230	COG1987	bacterial-type flagellum assembly
CXX03_RS10235	COG1684	flagellar biosynthetic protein fliR
CXX03_RS10240	COG2197	response regulator
CXX03_RS10260	COG3706	GGDEF domain
CXX03_RS10265	COG5475	Uncharacterized small protein (DUF2158)
CXX03_RS10270	COG2354	Protein conserved in bacteria
CXX03_RS10275	COG0697	spore germination
CXX03_RS10280	COG3727	T/G mismatch-specific endonuclease activity
CXX03_RS10285	COG0270	DNA (cytosine-5-)-methyltransferase activity
CXX03_RS10290	COG1418	mRNA catabolic process
CXX03_RS10300	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CXX03_RS10315	COG2205	protein histidine kinase activity
CXX03_RS10320	COG0745	RESPONSE REGULATOR receiver
CXX03_RS10325	COG2351	hydroxyisourate hydrolase activity
CXX03_RS10340	COG3443	Belongs to the bacterial solute-binding protein 9 family
CXX03_RS10345	COG3038	cytochrome b561
CXX03_RS10370	COG1388	LysM domain
CXX03_RS10370	COG1470	cell adhesion involved in biofilm formation
CXX03_RS10375	COG1470	cell adhesion involved in biofilm formation
CXX03_RS10375	COG1388	LysM domain
CXX03_RS10380	COG1470	cell adhesion involved in biofilm formation
CXX03_RS10380	COG1388	LysM domain
CXX03_RS10390	COG0477	Major facilitator Superfamily
CXX03_RS10395	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CXX03_RS10400	COG0217	transcriptional regulatory protein
CXX03_RS10410	COG0534	Mate efflux family protein
CXX03_RS10420	COG0583	DNA-binding transcription factor activity
CXX03_RS10425	COG0583	DNA-binding transcription factor activity
CXX03_RS10435	COG1376	ErfK ybiS ycfS ynhG family protein
CXX03_RS10450	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
CXX03_RS10455	COG4917	ethanolamine utilization protein
CXX03_RS10465	COG1289	transmembrane transporter activity
CXX03_RS10475	COG1686	Belongs to the peptidase S11 family
CXX03_RS10480	COG2925	Exonuclease
CXX03_RS10485	COG0425	Belongs to the sulfur carrier protein TusA family
CXX03_RS10495	COG0531	amino acid
CXX03_RS10505	COG0583	DNA-binding transcription factor activity
CXX03_RS10510	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CXX03_RS10515	COG4115	mRNA cleavage
CXX03_RS10520	COG2161	toxin-antitoxin pair type II binding
CXX03_RS10535	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CXX03_RS10545	COG0131	Imidazoleglycerol-phosphate dehydratase
CXX03_RS10545	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CXX03_RS10550	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CXX03_RS10580	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CXX03_RS10585	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CXX03_RS10590	COG0438	transferase activity, transferring glycosyl groups
CXX03_RS10625	COG1091	dTDP-4-dehydrorhamnose reductase activity
CXX03_RS10630	COG1088	dTDP-glucose 4,6-dehydratase activity
CXX03_RS10635	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CXX03_RS10645	COG0438	transferase activity, transferring glycosyl groups
CXX03_RS10650	COG2327	Polysaccharide pyruvyl transferase
CXX03_RS10655	COG2244	polysaccharide biosynthetic process
CXX03_RS10660	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CXX03_RS10665	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CXX03_RS10670	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CXX03_RS10670	COG0662	Cupin 2, conserved barrel domain protein
CXX03_RS10675	COG0297	glycogen (starch) synthase activity
CXX03_RS10680	COG1051	belongs to the nudix hydrolase family
CXX03_RS10685	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CXX03_RS10690	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CXX03_RS10695	COG0110	maltose O-acetyltransferase activity
CXX03_RS10700	COG1216	Glycosyl transferase, family 2
CXX03_RS10710	COG0438	transferase activity, transferring glycosyl groups
CXX03_RS10715	COG1045	serine acetyltransferase
CXX03_RS10720	COG0463	Glycosyl transferase, family 2
CXX03_RS10725	COG0489	protein tyrosine kinase activity
CXX03_RS10725	COG3206	protein involved in exopolysaccharide biosynthesis
CXX03_RS10730	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CXX03_RS10735	COG1596	polysaccharide export
CXX03_RS10740	COG1253	flavin adenine dinucleotide binding
CXX03_RS10745	COG2982	Protein involved in outer membrane biogenesis
CXX03_RS10755	COG0572	uridine kinase
CXX03_RS10760	COG3447	MASE1 domain protein
CXX03_RS10760	COG5002	protein histidine kinase activity
CXX03_RS10760	COG5001	Diguanylate cyclase
CXX03_RS10765	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CXX03_RS10770	COG0443	Heat shock 70 kDa protein
CXX03_RS10775	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
CXX03_RS10780	COG3779	Protein conserved in bacteria
CXX03_RS10785	COG0631	protein serine/threonine phosphatase activity
CXX03_RS10790	COG4245	von Willebrand factor, type A
CXX03_RS10830	COG2205	protein histidine kinase activity
CXX03_RS10835	COG0745	RESPONSE REGULATOR receiver
CXX03_RS10845	COG3609	addiction module antidote protein, CC2985 family
CXX03_RS10855	COG0826	peptidase U32
CXX03_RS10875	COG1063	alcohol dehydrogenase
CXX03_RS10880	COG3775	system Galactitol-specific IIC component
CXX03_RS10885	COG3414	Phosphotransferase system galactitol-specific IIB component
CXX03_RS10890	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX03_RS10905	COG1830	Aldolase
CXX03_RS10910	COG2211	Major facilitator Superfamily
CXX03_RS10915	COG1397	ADP-ribosylglycohydrolase
CXX03_RS10920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CXX03_RS10925	COG2188	Transcriptional regulator
CXX03_RS10930	COG3757	hydrolase, family 25
CXX03_RS10935	COG0351	phosphomethylpyrimidine kinase
CXX03_RS11005	COG5455	response to cobalt ion
CXX03_RS11010	COG3539	Fimbrial protein
CXX03_RS11015	COG3188	usher protein
CXX03_RS11020	COG3121	Chaperone
CXX03_RS11025	COG3539	Fimbrial protein
CXX03_RS11035	COG0489	protein tyrosine kinase activity
CXX03_RS11045	COG3831	ATPase activity
CXX03_RS11050	COG3831	ATPase activity
CXX03_RS11060	COG0714	Associated with various cellular activities
CXX03_RS11065	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CXX03_RS11070	COG3552	Protein containing von Willebrand factor type A (VWA) domain
CXX03_RS11075	COG4715	Zinc finger, swim domain protein
CXX03_RS11080	COG4808	Protein conserved in bacteria
CXX03_RS11085	COG4807	Protein conserved in bacteria
CXX03_RS11090	COG3279	Response regulator of the LytR AlgR family
CXX03_RS11095	COG3275	phosphorelay sensor kinase activity
CXX03_RS11100	COG0789	Transcriptional regulator
CXX03_RS11110	COG1174	glycine betaine transport
CXX03_RS11115	COG1125	glycine betaine transport
CXX03_RS11120	COG1174	glycine betaine transport
CXX03_RS11125	COG1732	Glycine betaine
CXX03_RS11130	COG1472	Belongs to the glycosyl hydrolase 3 family
CXX03_RS11135	COG0277	FAD linked oxidase domain protein
CXX03_RS11140	COG1686	Belongs to the peptidase S11 family
CXX03_RS11150	COG0586	Pfam SNARE associated Golgi protein
CXX03_RS11155	COG1028	Short-chain dehydrogenase reductase Sdr
CXX03_RS11170	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CXX03_RS11180	COG1346	cytolysis
CXX03_RS11190	COG2949	membrane
CXX03_RS11200	COG0493	'glutamate synthase
CXX03_RS11205	COG0167	dihydroorotate dehydrogenase activity
CXX03_RS11205	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CXX03_RS11210	COG4211	Belongs to the binding-protein-dependent transport system permease family
CXX03_RS11215	COG1129	ABC transporter
CXX03_RS11220	COG1879	ABC-type sugar transport system periplasmic component
CXX03_RS11225	COG1609	Transcriptional regulator
CXX03_RS11230	COG2311	Membrane
CXX03_RS11245	COG4771	TonB-dependent receptor
CXX03_RS11255	COG0833	amino acid
CXX03_RS11260	COG0583	DNA-binding transcription factor activity
CXX03_RS11265	COG2855	membrane
CXX03_RS11275	COG1522	sequence-specific DNA binding
CXX03_RS11275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CXX03_RS11280	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CXX03_RS11290	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CXX03_RS11295	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CXX03_RS11300	COG2313	pseudouridylate synthase activity
CXX03_RS11315	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CXX03_RS11315	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CXX03_RS11315	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CXX03_RS11320	COG1105	Belongs to the carbohydrate kinase PfkB family
CXX03_RS11325	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX03_RS11325	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX03_RS11330	COG2814	Major facilitator Superfamily
CXX03_RS11345	COG0246	Mannitol dehydrogenase
CXX03_RS11350	COG0523	cobalamin synthesis protein
CXX03_RS11355	COG0671	phosphoesterase, PA-phosphatase related
CXX03_RS11360	COG0791	NLP P60 protein
CXX03_RS11365	COG2200	EAL domain
CXX03_RS11370	COG4166	transmembrane transport
CXX03_RS11375	COG4174	ABC transporter (Permease)
CXX03_RS11380	COG4239	(ABC) transporter, permease
CXX03_RS11385	COG4172	Belongs to the ABC transporter superfamily
CXX03_RS11395	COG2814	Major facilitator Superfamily
CXX03_RS11400	COG1187	pseudouridine synthase activity
CXX03_RS11405	COG1061	Type III restriction enzyme res subunit
CXX03_RS11425	COG3083	sulfuric ester hydrolase activity
CXX03_RS11450	COG2197	response regulator
CXX03_RS11455	COG4235	cytochrome complex assembly
CXX03_RS11455	COG3088	subunit of a heme lyase
CXX03_RS11460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CXX03_RS11465	COG1138	Cytochrome C-type biogenesis protein
CXX03_RS11475	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CXX03_RS11480	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CXX03_RS11485	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CXX03_RS11495	COG3005	denitrification pathway
CXX03_RS11500	COG3043	anaerobic respiration
CXX03_RS11505	COG0348	domain, Protein
CXX03_RS11510	COG0437	4 iron, 4 sulfur cluster binding
CXX03_RS11520	COG3062	negative regulation of establishment of protein localization
CXX03_RS11525	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CXX03_RS11525	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
CXX03_RS11540	COG4615	Cyclic peptide transporter
CXX03_RS11545	COG3145	DNA-N1-methyladenine dioxygenase activity
CXX03_RS11550	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CXX03_RS11550	COG2169	Transcriptional regulator
CXX03_RS11555	COG1477	protein flavinylation
CXX03_RS11560	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CXX03_RS11565	COG0642	Histidine kinase
CXX03_RS11565	COG2198	Histidine kinase
CXX03_RS11570	COG2197	response regulator
CXX03_RS11575	COG2205	protein histidine kinase activity
CXX03_RS11575	COG0784	Response regulator, receiver
CXX03_RS11580	COG4676	Protein conserved in bacteria
CXX03_RS11585	COG5445	Predicted secreted protein (DUF2300)
CXX03_RS11590	COG2373	Large extracellular alpha-helical protein
CXX03_RS11595	COG3234	Protein of unknown function (DUF1175)
CXX03_RS11600	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
CXX03_RS11605	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CXX03_RS11615	COG3468	outer membrane autotransporter barrel domain protein
CXX03_RS11620	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CXX03_RS11625	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CXX03_RS11630	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CXX03_RS11635	COG3642	lipopolysaccharide core region biosynthetic process
CXX03_RS11645	COG0584	glycerophosphoryl diester phosphodiesterase
CXX03_RS11650	COG2271	Major facilitator Superfamily
CXX03_RS11655	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CXX03_RS11665	COG0247	lactate metabolic process
CXX03_RS11670	COG5464	transposase or invertase
CXX03_RS11740	COG0318	PFAM AMP-dependent synthetase and ligase
CXX03_RS11750	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CXX03_RS11765	COG1169	isochorismate synthase
CXX03_RS11770	COG4575	ribosome binding
CXX03_RS11775	COG2153	protein acetylation
CXX03_RS11805	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CXX03_RS11810	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CXX03_RS11820	COG0839	Belongs to the complex I subunit 6 family
CXX03_RS11835	COG1034	ATP synthesis coupled electron transport
CXX03_RS11840	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CXX03_RS11845	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CXX03_RS11865	COG0583	DNA-binding transcription factor activity
CXX03_RS11875	COG0436	Aminotransferase
CXX03_RS11885	COG0490	domain, Protein
CXX03_RS11885	COG0471	metal ion transport
CXX03_RS11890	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CXX03_RS11905	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CXX03_RS11910	COG0280	phosphate acetyltransferase
CXX03_RS11910	COG0857	belongs to the CobB CobQ family
CXX03_RS11915	COG1288	antiporter activity
CXX03_RS11920	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CXX03_RS11925	COG0622	Phosphoesterase
CXX03_RS11930	COG0625	glutathione transferase activity
CXX03_RS11935	COG0625	glutathione transferase activity
CXX03_RS11940	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CXX03_RS11945	COG1090	epimerase
CXX03_RS11950	COG5464	transposase or invertase
CXX03_RS11955	COG4598	ABC transporter
CXX03_RS11960	COG4160	amino acid transport
CXX03_RS11965	COG4215	(ABC) transporter
CXX03_RS11970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXX03_RS11975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXX03_RS11980	COG0163	prenyltransferase activity
CXX03_RS11985	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CXX03_RS11990	COG1286	toxin biosynthetic process
CXX03_RS11995	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CXX03_RS12000	COG0285	dihydrofolate synthase activity
CXX03_RS12010	COG0586	Pfam SNARE associated Golgi protein
CXX03_RS12020	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CXX03_RS12030	COG4974	Belongs to the 'phage' integrase family
CXX03_RS12120	COG4695	Portal protein
CXX03_RS12215	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CXX03_RS12225	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CXX03_RS12305	COG2814	Major facilitator Superfamily
CXX03_RS12310	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CXX03_RS12320	COG3547	Transposase (IS116 IS110 IS902 family)
CXX03_RS12335	COG3101	peptidyl-lysine hydroxylation
CXX03_RS12340	COG0730	response to heat
CXX03_RS12370	COG3539	Fimbrial protein
CXX03_RS12375	COG3539	Fimbrial protein
CXX03_RS12385	COG3539	Fimbrial protein
CXX03_RS12390	COG3121	Chaperone
CXX03_RS12395	COG3188	usher protein
CXX03_RS12400	COG3539	Fimbrial protein
CXX03_RS12405	COG2062	phosphohistidine phosphatase, SixA
CXX03_RS12420	COG3691	Protein conserved in bacteria
CXX03_RS12425	COG2067	long-chain fatty acid transport protein
CXX03_RS12435	COG2853	Lipoprotein
CXX03_RS12440	COG2116	formate transmembrane transporter activity
CXX03_RS12480	COG0477	Major facilitator Superfamily
CXX03_RS12485	COG1566	PFAM secretion protein HlyD family protein
CXX03_RS12490	COG2197	response regulator
CXX03_RS12495	COG0784	Response regulator, receiver
CXX03_RS12495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXX03_RS12495	COG2198	Histidine kinase
CXX03_RS12495	COG2205	protein histidine kinase activity
CXX03_RS12500	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CXX03_RS12505	COG0679	Auxin Efflux Carrier
CXX03_RS12510	COG0028	Belongs to the TPP enzyme family
CXX03_RS12535	COG1560	Kdo2-lipid A biosynthetic process
CXX03_RS12545	COG0436	Aminotransferase
CXX03_RS12550	COG3275	phosphorelay sensor kinase activity
CXX03_RS12555	COG3279	Response regulator of the LytR AlgR family
CXX03_RS12560	COG2207	Transcriptional regulator
CXX03_RS12570	COG1363	Peptidase, m42
CXX03_RS12575	COG0006	proline dipeptidase activity
CXX03_RS12580	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CXX03_RS12585	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CXX03_RS12610	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CXX03_RS12615	COG2199	diguanylate cyclase activity
CXX03_RS12615	COG2200	EAL domain
CXX03_RS12630	COG3415	Transposase
CXX03_RS12635	COG3415	Transposase
CXX03_RS12675	COG0583	DNA-binding transcription factor activity
CXX03_RS12680	COG0385	Bile acid
CXX03_RS12685	COG3530	Putative quorum-sensing-regulated virulence factor
CXX03_RS12705	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CXX03_RS12710	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX03_RS12715	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CXX03_RS12720	COG2190	(PTS) system
CXX03_RS12735	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CXX03_RS12740	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CXX03_RS12745	COG4208	sulfate ABC transporter
CXX03_RS12750	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CXX03_RS12755	COG4150	thiosulfate binding
CXX03_RS12760	COG1028	Short-chain dehydrogenase reductase Sdr
CXX03_RS12775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXX03_RS12775	COG1263	PTS System
CXX03_RS12780	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CXX03_RS12785	COG2837	iron assimilation
CXX03_RS12805	COG0860	N-Acetylmuramoyl-L-alanine amidase
CXX03_RS12815	COG2207	Transcriptional regulator
CXX03_RS12820	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CXX03_RS12825	COG4816	utilization protein
CXX03_RS12835	COG4303	Ethanolamine ammonia lyase large subunit
CXX03_RS12840	COG4819	ethanolamine utilization protein
CXX03_RS12845	COG3192	ethanolamine utilization protein
CXX03_RS12850	COG1454	alcohol dehydrogenase
CXX03_RS12855	COG4820	ethanolamine utilization protein (EutJ)
CXX03_RS12860	COG1012	belongs to the aldehyde dehydrogenase family
CXX03_RS12865	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
CXX03_RS12870	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CXX03_RS12875	COG0280	phosphate acetyltransferase
CXX03_RS12880	COG4812	Cobalamin adenosyltransferase
CXX03_RS12885	COG4766	ethanolamine catabolic process
CXX03_RS12890	COG4917	ethanolamine utilization protein
CXX03_RS12895	COG4810	utilization protein
CXX03_RS12905	COG0281	malic enzyme
CXX03_RS12905	COG0280	phosphate acetyltransferase
CXX03_RS12910	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CXX03_RS12915	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CXX03_RS12920	COG5342	invasion associated locus B
CXX03_RS12930	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CXX03_RS12930	COG0493	'glutamate synthase
CXX03_RS12935	COG3850	Histidine kinase
CXX03_RS12940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CXX03_RS12950	COG1393	Belongs to the ArsC family
CXX03_RS12965	COG0400	carboxylic ester hydrolase activity
CXX03_RS12975	COG2321	neutral zinc metallopeptidase
CXX03_RS12995	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CXX03_RS13005	COG2716	regulation of RNA biosynthetic process
CXX03_RS13010	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CXX03_RS13015	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CXX03_RS13025	COG0650	Formate hydrogenlyase subunit 4
CXX03_RS13030	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CXX03_RS13040	COG4237	Hydrogenase 4 membrane
CXX03_RS13050	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CXX03_RS13050	COG3261	NADH dehydrogenase
CXX03_RS13055	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CXX03_RS13060	COG3260	NADH ubiquinone oxidoreductase 20
CXX03_RS13070	COG3604	Transcriptional regulator
CXX03_RS13075	COG2116	formate transmembrane transporter activity
CXX03_RS13080	COG2116	formate transmembrane transporter activity
CXX03_RS13085	COG0628	permease
CXX03_RS13090	COG4783	chaperone-mediated protein folding
CXX03_RS13095	COG1393	Belongs to the ArsC family
CXX03_RS13105	COG2233	PERMEase
CXX03_RS13120	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CXX03_RS13125	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CXX03_RS13130	COG0248	Ppx GppA phosphatase
CXX03_RS13135	COG2200	EAL domain
CXX03_RS13145	COG3133	Outer membrane lipoprotein
CXX03_RS13185	COG0556	nucleotide-excision repair
CXX03_RS13210	COG5314	conjugation
CXX03_RS13245	COG0582	viral genome integration into host DNA
CXX03_RS13255	COG0516	GMP reductase activity
CXX03_RS13255	COG0517	IMP dehydrogenase activity
CXX03_RS13265	COG1645	bacterial-type flagellum-dependent swarming motility
CXX03_RS13280	COG2976	Protein conserved in bacteria
CXX03_RS13310	COG4953	penicillin-binding protein 1C
CXX03_RS13315	COG2373	Large extracellular alpha-helical protein
CXX03_RS13320	COG2897	thiosulfate sulfurtransferase activity
CXX03_RS13335	COG2975	iron-sulfur cluster assembly
CXX03_RS13340	COG0633	Ferredoxin
CXX03_RS13360	COG0822	iron-sulfur transferase activity
CXX03_RS13380	COG0483	inositol monophosphate 1-phosphatase activity
CXX03_RS13385	COG1073	alpha beta
CXX03_RS13390	COG3711	transcriptional antiterminator
CXX03_RS13395	COG2814	Major facilitator Superfamily
CXX03_RS13400	COG0583	DNA-binding transcription factor activity
CXX03_RS13405	COG4638	Rieske (2fe-2S)
CXX03_RS13430	COG2259	Doxx family
CXX03_RS13435	COG2017	converts alpha-aldose to the beta-anomer
CXX03_RS13440	COG1063	alcohol dehydrogenase
CXX03_RS13445	COG1172	Belongs to the binding-protein-dependent transport system permease family
CXX03_RS13450	COG1129	ABC transporter
CXX03_RS13455	COG1879	ABC-type sugar transport system periplasmic component
CXX03_RS13460	COG0457	Tetratricopeptide repeat
CXX03_RS13465	COG1940	carbohydrate kinase activity
CXX03_RS13475	COG1017	nitric oxide dioxygenase activity
CXX03_RS13475	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CXX03_RS13480	COG0347	Belongs to the P(II) protein family
CXX03_RS13485	COG2204	response regulator
CXX03_RS13490	COG3170	Tfp pilus assembly protein FimV
CXX03_RS13495	COG2205	protein histidine kinase activity
CXX03_RS13500	COG0047	phosphoribosylformylglycinamidine synthase activity
CXX03_RS13500	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CXX03_RS13515	COG0560	Phosphoserine phosphatase
CXX03_RS13520	COG1737	Transcriptional regulator
CXX03_RS13525	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CXX03_RS13540	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CXX03_RS13560	COG0681	Belongs to the peptidase S26 family
CXX03_RS13570	COG3086	response to oxidative stress
CXX03_RS13575	COG3026	antisigma factor binding
CXX03_RS13580	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
CXX03_RS13585	COG1595	DNA-templated transcription, initiation
CXX03_RS13595	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CXX03_RS13605	COG0513	Belongs to the DEAD box helicase family
CXX03_RS13610	COG0583	DNA-binding transcription factor activity
CXX03_RS13635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CXX03_RS13640	COG3118	belongs to the thioredoxin family
CXX03_RS13645	COG3148	PFAM DTW domain containing protein
CXX03_RS13650	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CXX03_RS13650	COG1042	CoA-binding domain protein
CXX03_RS13650	COG0045	succinate-CoA ligase (ADP-forming) activity
CXX03_RS13655	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CXX03_RS13660	COG5544	Lipoprotein
CXX03_RS13665	COG0477	Major facilitator Superfamily
CXX03_RS13690	COG0542	response to heat
CXX03_RS13695	COG1496	oxidoreductase activity
CXX03_RS13700	COG0564	pseudouridine synthase activity
CXX03_RS13705	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CXX03_RS13710	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CXX03_RS13720	COG1605	Chorismate mutase
CXX03_RS13720	COG0077	Prephenate dehydratase
CXX03_RS13725	COG1605	Chorismate mutase
CXX03_RS13725	COG0287	Prephenate dehydrogenase
CXX03_RS13730	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CXX03_RS13745	COG2199	diguanylate cyclase activity
CXX03_RS13750	COG2885	chlorophyll binding
CXX03_RS13775	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CXX03_RS13780	COG4137	Cytochrome C assembly protein
CXX03_RS13785	COG4536	flavin adenine dinucleotide binding
CXX03_RS13805	COG0497	DNA recombination
CXX03_RS13810	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CXX03_RS13820	COG2867	negative regulation of translational initiation
CXX03_RS13835	COG0582	viral genome integration into host DNA
CXX03_RS13870	COG0579	oxidoreductase
CXX03_RS13875	COG1012	belongs to the aldehyde dehydrogenase family
CXX03_RS13880	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CXX03_RS13885	COG1113	amino acid transport
CXX03_RS13890	COG1802	Transcriptional regulator
CXX03_RS13895	COG1652	LysM domain
CXX03_RS13900	COG0401	homolog of Blt101
CXX03_RS13905	COG0640	Transcriptional regulator
CXX03_RS13910	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CXX03_RS13915	COG2916	Histone family protein nucleoid-structuring protein H-NS
CXX03_RS13930	COG4575	ribosome binding
CXX03_RS13935	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CXX03_RS13945	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CXX03_RS13950	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CXX03_RS13955	COG4175	Glycine betaine
CXX03_RS13960	COG4176	ABC-type proline glycine betaine transport system permease component
CXX03_RS13965	COG2113	Glycine betaine
CXX03_RS13970	COG2814	Major facilitator Superfamily
CXX03_RS13975	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CXX03_RS13985	COG1846	Transcriptional regulator
CXX03_RS13990	COG1566	PFAM secretion protein HlyD family protein
CXX03_RS13995	COG2814	Major facilitator Superfamily
CXX03_RS14010	COG1238	metal cluster binding
CXX03_RS14015	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CXX03_RS14045	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CXX03_RS14065	COG1546	Belongs to the CinA family
CXX03_RS14070	COG2951	lytic endotransglycosylase activity
CXX03_RS14075	COG3730	PTS system glucitol sorbitol-specific
CXX03_RS14080	COG3732	PTS system glucitol sorbitol-specific
CXX03_RS14085	COG3731	PTS system glucitol sorbitol-specific IIA component
CXX03_RS14090	COG1028	Short-chain dehydrogenase reductase Sdr
CXX03_RS14095	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX03_RS14100	COG1349	DNA-binding transcription factor activity
CXX03_RS14125	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CXX03_RS14130	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CXX03_RS14135	COG1609	Transcriptional regulator
CXX03_RS14140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXX03_RS14140	COG1263	PTS System
CXX03_RS14145	COG2723	6-phospho-beta-galactosidase activity
CXX03_RS14150	COG3547	Transposase (IS116 IS110 IS902 family)
CXX03_RS14160	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CXX03_RS14170	COG3260	NADH ubiquinone oxidoreductase 20
CXX03_RS14175	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CXX03_RS14180	COG3261	NADH dehydrogenase
CXX03_RS14180	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CXX03_RS14185	COG0650	Formate hydrogenlyase subunit 4
CXX03_RS14190	COG0651	ATP synthesis coupled electron transport
CXX03_RS14195	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CXX03_RS14210	COG0375	protein maturation
CXX03_RS14215	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CXX03_RS14220	COG0298	carbon dioxide binding
CXX03_RS14225	COG0409	Hydrogenase expression formation protein
CXX03_RS14230	COG0309	Hydrogenase expression formation protein (HypE)
CXX03_RS14235	COG3604	Transcriptional regulator
CXX03_RS14250	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CXX03_RS14255	COG1349	DNA-binding transcription factor activity
CXX03_RS14260	COG2084	Dehydrogenase
CXX03_RS14265	COG3395	kinase activity
CXX03_RS14270	COG0235	Class ii aldolase
CXX03_RS14275	COG3622	Belongs to the hyi family
CXX03_RS14280	COG2610	gluconate transmembrane transporter activity
CXX03_RS14305	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CXX03_RS14310	COG1388	LysM domain
CXX03_RS14310	COG4942	peptidase
CXX03_RS14365	COG2234	aminopeptidase activity
CXX03_RS14370	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CXX03_RS14375	COG1518	maintenance of DNA repeat elements
CXX03_RS14390	COG1857	crispr-associated protein
CXX03_RS14405	COG1203	CRISPR-associated helicase, Cas3
CXX03_RS14440	COG0720	synthase
CXX03_RS14445	COG1070	Carbohydrate kinase
CXX03_RS14450	COG0602	queuosine metabolic process
CXX03_RS14460	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CXX03_RS14480	COG3956	TIGRFAM MazG family protein
CXX03_RS14485	COG2337	Toxic component of a toxin-antitoxin (TA) module
CXX03_RS14490	COG2336	PFAM SpoVT AbrB
CXX03_RS14495	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CXX03_RS14505	COG3437	response regulator, receiver
CXX03_RS14505	COG3850	Histidine kinase
CXX03_RS14505	COG4999	Histidine kinase
CXX03_RS14505	COG2205	protein histidine kinase activity
CXX03_RS14510	COG4948	Mandelate Racemase Muconate Lactonizing
CXX03_RS14515	COG4948	Mandelate Racemase Muconate Lactonizing
CXX03_RS14520	COG2271	Major facilitator Superfamily
CXX03_RS14525	COG0716	FMN binding
CXX03_RS14530	COG0564	pseudouridine synthase activity
CXX03_RS14535	COG3098	single-species biofilm formation
CXX03_RS14550	COG1611	Belongs to the LOG family
CXX03_RS14555	COG0814	amino acid
CXX03_RS14560	COG1760	l-serine dehydratase
CXX03_RS14570	COG1454	alcohol dehydrogenase
CXX03_RS14575	COG0235	Class ii aldolase
CXX03_RS14580	COG0738	Major facilitator superfamily
CXX03_RS14590	COG1070	Carbohydrate kinase
CXX03_RS14600	COG1349	DNA-binding transcription factor activity
CXX03_RS14610	COG2363	Small membrane protein
CXX03_RS14615	COG0583	DNA-binding transcription factor activity
CXX03_RS14625	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CXX03_RS14630	COG2166	iron-sulfur cluster assembly
CXX03_RS14635	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CXX03_RS14640	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CXX03_RS14680	COG2885	chlorophyll binding
CXX03_RS14730	COG0860	N-Acetylmuramoyl-L-alanine amidase
CXX03_RS14735	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CXX03_RS14735	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CXX03_RS14740	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CXX03_RS14745	COG1074	ATP-dependent DNA helicase activity
CXX03_RS14750	COG1025	Belongs to the peptidase M16 family
CXX03_RS14755	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CXX03_RS14760	COG4967	type IV pilus modification protein PilV
CXX03_RS14770	COG4795	General secretion pathway protein
CXX03_RS14775	COG2165	general secretion pathway protein
CXX03_RS14790	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
CXX03_RS14810	COG0861	Integral membrane protein TerC family
CXX03_RS14820	COG0667	Aldo Keto reductase
CXX03_RS14835	COG1609	Transcriptional regulator
CXX03_RS14845	COG0583	DNA-binding transcription factor activity
CXX03_RS14850	COG1794	racemase activity, acting on amino acids and derivatives
CXX03_RS14855	COG2814	Major facilitator Superfamily
CXX03_RS14860	COG1028	Short-chain dehydrogenase reductase Sdr
CXX03_RS14870	COG0183	Belongs to the thiolase family
CXX03_RS14875	COG0814	amino acid
CXX03_RS14880	COG2771	luxR family
CXX03_RS14885	COG3710	Transcriptional regulator
CXX03_RS14915	COG0457	Tetratricopeptide repeat
CXX03_RS14920	COG3710	Transcriptional regulator
CXX03_RS14920	COG0457	Tetratricopeptide repeat
CXX03_RS15030	COG3387	PFAM Glycoside hydrolase 15-related
CXX03_RS15130	COG4942	peptidase
CXX03_RS15135	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CXX03_RS15140	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CXX03_RS15145	COG2080	2 iron, 2 sulfur cluster binding
CXX03_RS15150	COG3829	transcription factor binding
CXX03_RS15155	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CXX03_RS15160	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CXX03_RS15165	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CXX03_RS15175	COG0549	Belongs to the carbamate kinase family
CXX03_RS15180	COG3608	succinylglutamate desuccinylase aspartoacylase
CXX03_RS15180	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CXX03_RS15185	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CXX03_RS15190	COG2068	MobA-Related Protein
CXX03_RS15195	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CXX03_RS15195	COG0493	'glutamate synthase
CXX03_RS15200	COG0402	S-adenosylhomocysteine deaminase activity
CXX03_RS15205	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CXX03_RS15210	COG2080	2 iron, 2 sulfur cluster binding
CXX03_RS15210	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CXX03_RS15215	COG2233	PERMEase
CXX03_RS15220	COG0402	S-adenosylhomocysteine deaminase activity
CXX03_RS15225	COG2252	PERMEase
CXX03_RS15230	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CXX03_RS15235	COG0493	'glutamate synthase
CXX03_RS15235	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CXX03_RS15240	COG2233	PERMEase
CXX03_RS15270	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CXX03_RS15275	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CXX03_RS15280	COG4974	Belongs to the 'phage' integrase family
CXX03_RS15285	COG0716	FMN binding
CXX03_RS15295	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CXX03_RS15305	COG1272	protein, Hemolysin III
CXX03_RS15315	COG2723	6-phospho-beta-galactosidase activity
CXX03_RS15320	COG1028	Short-chain dehydrogenase reductase Sdr
CXX03_RS15345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CXX03_RS15350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CXX03_RS15355	COG0006	proline dipeptidase activity
CXX03_RS15375	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CXX03_RS15390	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CXX03_RS15410	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CXX03_RS15410	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CXX03_RS15415	COG1703	isobutyryl-CoA mutase activity
CXX03_RS15420	COG1024	Enoyl-CoA hydratase
CXX03_RS15425	COG0427	acetyl-CoA hydrolase
CXX03_RS15430	COG0583	DNA-binding transcription factor activity
CXX03_RS15435	COG2968	Membrane
CXX03_RS15440	COG1279	arginine transmembrane transporter activity
CXX03_RS15445	COG0668	transmembrane transport
CXX03_RS15450	COG0191	fructose-bisphosphate aldolase activity
CXX03_RS15480	COG1122	ATPase activity
CXX03_RS15485	COG1122	ATPase activity
CXX03_RS15490	COG1072	(Pantothenic acid kinase))
CXX03_RS15500	COG1494	fructose-1,6-bisphosphatase
CXX03_RS15505	COG1063	alcohol dehydrogenase
CXX03_RS15510	COG2213	PTS system mannitol-specific
CXX03_RS15515	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX03_RS15520	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CXX03_RS15525	COG0501	Belongs to the peptidase M48B family
CXX03_RS15540	COG3716	PTS system mannose fructose sorbose family IID component
CXX03_RS15545	COG3715	PTS system
CXX03_RS15550	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXX03_RS15550	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX03_RS15575	COG1166	arginine decarboxylase activity
CXX03_RS15600	COG2814	Major facilitator Superfamily
CXX03_RS15610	COG2356	endonuclease I
CXX03_RS15615	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CXX03_RS15620	COG0189	ligase activity
CXX03_RS15635	COG2805	Type II/IV secretion system protein
CXX03_RS15640	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CXX03_RS15645	COG0762	integral membrane protein
CXX03_RS15660	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CXX03_RS15670	COG0252	asparaginase activity
CXX03_RS15680	COG3171	Protein conserved in bacteria
CXX03_RS15690	COG1194	a g-specific adenine glycosylase
CXX03_RS15705	COG2211	Major facilitator Superfamily
CXX03_RS15710	COG1982	Orn Lys Arg decarboxylase major
CXX03_RS15715	COG1811	Na channel or pump
CXX03_RS15730	COG0754	glutathionylspermidine amidase activity
CXX03_RS15735	COG0625	glutathione transferase activity
CXX03_RS15745	COG3547	Transposase (IS116 IS110 IS902 family)
CXX03_RS15750	COG0298	carbon dioxide binding
CXX03_RS15760	COG1773	rubredoxin
CXX03_RS15765	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CXX03_RS15770	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CXX03_RS15775	COG5557	Pfam Polysulphide reductase, NrfD
CXX03_RS15780	COG0437	4 iron, 4 sulfur cluster binding
CXX03_RS15785	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CXX03_RS15805	COG0667	Aldo Keto reductase
CXX03_RS15815	COG1028	Short-chain dehydrogenase reductase Sdr
CXX03_RS15820	COG0848	biopolymer transport protein
CXX03_RS15825	COG0811	peptide transport
CXX03_RS15830	COG0626	cystathionine gamma-synthase activity
CXX03_RS15835	COG0586	Pfam SNARE associated Golgi protein
CXX03_RS15840	COG2207	Transcriptional regulator
CXX03_RS15845	COG1979	alcohol dehydrogenase
CXX03_RS15850	COG0656	L-ascorbic acid biosynthetic process
CXX03_RS15860	COG4238	major outer membrane lipoprotein
CXX03_RS15865	COG1032	radical SAM domain protein
CXX03_RS15870	COG2132	Multicopper oxidase
CXX03_RS15875	COG0204	Acyl-transferase
CXX03_RS15880	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CXX03_RS15885	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CXX03_RS15890	COG3111	PFAM Bacterial OB fold (BOF) protein
CXX03_RS15895	COG0745	RESPONSE REGULATOR receiver
CXX03_RS15900	COG0642	Histidine kinase
CXX03_RS15910	COG2249	NAD(P)H dehydrogenase (quinone) activity
CXX03_RS15915	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CXX03_RS15920	COG0187	DNA topoisomerase II activity
CXX03_RS15925	COG3150	esterase
CXX03_RS15930	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CXX03_RS15935	COG3151	Protein conserved in bacteria
CXX03_RS15940	COG0494	nUDIX hydrolase
CXX03_RS15945	COG1538	Outer membrane efflux protein
CXX03_RS15955	COG0754	glutathionylspermidine amidase activity
CXX03_RS15960	COG3384	dioxygenase
CXX03_RS15975	COG2960	long-chain fatty acid transporting porin activity
CXX03_RS15980	COG3539	Fimbrial protein
CXX03_RS15985	COG3188	usher protein
CXX03_RS15995	COG3539	Fimbrial protein
CXX03_RS16005	COG1585	Membrane protein implicated in regulation of membrane protease activity
CXX03_RS16010	COG2268	Band 7 protein
CXX03_RS16035	COG3025	triphosphatase activity
CXX03_RS16040	COG4991	sh3 domain protein
CXX03_RS16055	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CXX03_RS16065	COG0583	DNA-binding transcription factor activity
CXX03_RS16070	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CXX03_RS16075	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CXX03_RS16080	COG0471	metal ion transport
CXX03_RS16090	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CXX03_RS16095	COG0358	DNA primase activity
CXX03_RS16100	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CXX03_RS16115	COG2375	cellular response to nickel ion
CXX03_RS16125	COG1695	Transcriptional regulator
CXX03_RS16130	COG0840	transmembrane signaling receptor activity
CXX03_RS16140	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CXX03_RS16145	COG1609	Transcriptional regulator
CXX03_RS16150	COG3250	beta-galactosidase activity
CXX03_RS16155	COG2731	YhcH YjgK YiaL family protein
CXX03_RS16170	COG3408	Glycogen debranching enzyme
CXX03_RS16170	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
CXX03_RS16175	COG1902	pentaerythritol trinitrate reductase activity
CXX03_RS16175	COG0446	pyridine nucleotide-disulphide oxidoreductase
CXX03_RS16180	COG5499	transcription regulator containing HTH domain
CXX03_RS16195	COG1451	nucleotide metabolic process
CXX03_RS16200	COG2949	membrane
CXX03_RS16205	COG0673	inositol 2-dehydrogenase activity
CXX03_RS16210	COG0861	Integral membrane protein TerC family
CXX03_RS16215	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CXX03_RS16225	COG2721	sulfolactate sulfo-lyase activity
CXX03_RS16235	COG2271	Major facilitator Superfamily
CXX03_RS16270	COG2186	Transcriptional regulator
CXX03_RS16275	COG0586	Pfam SNARE associated Golgi protein
CXX03_RS16285	COG1422	Protein of unknown function (DUF1090)
CXX03_RS16290	COG4575	ribosome binding
CXX03_RS16295	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CXX03_RS16305	COG2259	Doxx family
CXX03_RS16310	COG0435	Glutathione S-transferase
CXX03_RS16315	COG3152	Membrane
CXX03_RS16320	COG3152	Membrane
CXX03_RS16325	COG0583	DNA-binding transcription factor activity
CXX03_RS16330	COG1741	Belongs to the pirin family
CXX03_RS16345	COG0814	amino acid
CXX03_RS16350	COG1760	l-serine dehydratase
CXX03_RS16355	COG0251	oxidation-reduction process
CXX03_RS16360	COG1882	Formate acetyltransferase
CXX03_RS16365	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CXX03_RS16375	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CXX03_RS16380	COG0583	DNA-binding transcription factor activity
CXX03_RS16405	COG1929	Belongs to the glycerate kinase type-1 family
CXX03_RS16410	COG2084	Dehydrogenase
CXX03_RS16420	COG2271	Major facilitator Superfamily
CXX03_RS16425	COG2721	sulfolactate sulfo-lyase activity
CXX03_RS16430	COG2002	toxin-antitoxin pair type II binding
CXX03_RS16440	COG1349	DNA-binding transcription factor activity
CXX03_RS16450	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXX03_RS16460	COG3716	PTS system mannose fructose sorbose family IID component
CXX03_RS16465	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX03_RS16470	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CXX03_RS16475	COG2222	sugar isomerase
CXX03_RS16485	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXX03_RS16490	COG3715	PTS system
CXX03_RS16495	COG3716	PTS system mannose fructose sorbose family IID component
CXX03_RS16500	COG0363	glucosamine-6-phosphate deaminase activity
CXX03_RS16505	COG3539	Fimbrial protein
CXX03_RS16510	COG3121	Chaperone
CXX03_RS16515	COG3188	usher protein
CXX03_RS16520	COG3539	Fimbrial protein
CXX03_RS16525	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CXX03_RS16545	COG2823	Periplasmic or secreted lipoprotein
CXX03_RS16550	COG0701	Predicted permease
CXX03_RS16555	COG0702	epimerase
CXX03_RS16560	COG0693	protein deglycase activity
CXX03_RS16575	COG3153	acetyltransferase
CXX03_RS16580	COG3154	lipid carrier protein
CXX03_RS16585	COG0826	peptidase U32
CXX03_RS16590	COG0826	peptidase U32
CXX03_RS16595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CXX03_RS16600	COG3547	Transposase (IS116 IS110 IS902 family)
CXX03_RS16610	COG0814	amino acid
CXX03_RS16615	COG0513	Belongs to the DEAD box helicase family
CXX03_RS16655	COG0195	Participates in both transcription termination and antitermination
CXX03_RS16675	COG2194	sulfuric ester hydrolase activity
CXX03_RS16685	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CXX03_RS16695	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CXX03_RS16700	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CXX03_RS16710	COG1534	Rna-binding protein
CXX03_RS16715	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CXX03_RS16720	COG2027	D-alanyl-D-alanine carboxypeptidase
CXX03_RS16730	COG0697	spore germination
CXX03_RS16745	COG0142	geranyltranstransferase activity
CXX03_RS16750	COG3423	Transcriptional regulator
CXX03_RS16760	COG5007	Belongs to the BolA IbaG family
CXX03_RS16765	COG3113	response to antibiotic
CXX03_RS16770	COG2854	intermembrane phospholipid transfer
CXX03_RS16775	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CXX03_RS16780	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CXX03_RS16785	COG1127	ABC transporter
CXX03_RS16790	COG0530	calcium, potassium:sodium antiporter activity
CXX03_RS16795	COG0517	IMP dehydrogenase activity
CXX03_RS16795	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CXX03_RS16800	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CXX03_RS16805	COG3117	lipopolysaccharide transmembrane transporter activity
CXX03_RS16810	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CXX03_RS16815	COG1137	ATPase activity
CXX03_RS16820	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CXX03_RS16825	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CXX03_RS16840	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX03_RS16845	COG0515	serine threonine protein kinase
CXX03_RS16855	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CXX03_RS16860	COG2198	Histidine kinase
CXX03_RS16860	COG5002	protein histidine kinase activity
CXX03_RS16860	COG0784	Response regulator, receiver
CXX03_RS16865	COG1242	4 iron, 4 sulfur cluster binding
CXX03_RS16870	COG0070	glutamate synthase
CXX03_RS16870	COG0069	glutamate synthase activity
CXX03_RS16870	COG0067	glutamate synthase
CXX03_RS16875	COG0493	'glutamate synthase
CXX03_RS16880	COG4804	nuclease activity
CXX03_RS16890	COG2731	YhcH YjgK YiaL family protein
CXX03_RS16920	COG3069	C4-dicarboxylate transmembrane transporter activity
CXX03_RS16925	COG2969	positive regulation of protein catabolic process
CXX03_RS16930	COG0625	glutathione transferase activity
CXX03_RS16950	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CXX03_RS16955	COG3105	Protein conserved in bacteria
CXX03_RS16960	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CXX03_RS16965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CXX03_RS16985	COG2732	(Barnase) inhibitor
CXX03_RS17005	COG0583	DNA-binding transcription factor activity
CXX03_RS17010	COG0312	modulator of DNA gyrase
CXX03_RS17015	COG3164	Protein of unknown function
CXX03_RS17020	COG1530	ribonuclease E activity
CXX03_RS17030	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CXX03_RS17035	COG1792	Involved in formation and maintenance of cell shape
CXX03_RS17040	COG1077	Cell shape determining protein MreB Mrl
CXX03_RS17050	COG2199	diguanylate cyclase activity
CXX03_RS17050	COG2200	EAL domain
CXX03_RS17055	COG0604	alcohol dehydrogenase
CXX03_RS17060	COG0511	ligase activity, forming carbon-carbon bonds
CXX03_RS17065	COG0439	Biotin carboxylase
CXX03_RS17070	COG3924	membrane
CXX03_RS17075	COG4145	pantothenate transmembrane transporter activity
CXX03_RS17085	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CXX03_RS17095	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CXX03_RS17105	COG1309	transcriptional regulator
CXX03_RS17110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CXX03_RS17115	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CXX03_RS17125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXX03_RS17130	COG4597	amino acid ABC transporter
CXX03_RS17135	COG0765	amino acid transport
CXX03_RS17140	COG1126	abc transporter atp-binding protein
CXX03_RS17180	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CXX03_RS17200	COG0551	DNA topoisomerase type I activity
CXX03_RS17210	COG0758	DNA mediated transformation
CXX03_RS17230	COG0569	domain protein
CXX03_RS17240	COG3036	rescue of stalled ribosome
CXX03_RS17245	COG0789	Transcriptional regulator
CXX03_RS17285	COG0201	protein transport
CXX03_RS17375	COG0089	rRNA binding
CXX03_RS17445	COG2964	Protein conserved in bacteria
CXX03_RS17450	COG0545	Peptidyl-prolyl cis-trans isomerase
CXX03_RS17460	COG1047	Peptidyl-prolyl cis-trans
CXX03_RS17465	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CXX03_RS17480	COG0488	(ABC) transporter
CXX03_RS17485	COG0429	hydrolase of the alpha beta-hydrolase fold
CXX03_RS17495	COG3954	Phosphoribulokinase
CXX03_RS17500	COG1765	OsmC-like protein
CXX03_RS17505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CXX03_RS17510	COG1289	transmembrane transporter activity
CXX03_RS17515	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CXX03_RS17520	COG0512	Glutamine amidotransferase of anthranilate synthase
CXX03_RS17525	COG2184	nucleotidyltransferase activity
CXX03_RS17535	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CXX03_RS17545	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CXX03_RS17550	COG2146	nitrite reductase [NAD(P)H] activity
CXX03_RS17555	COG2116	formate transmembrane transporter activity
CXX03_RS17570	COG0531	amino acid
CXX03_RS17575	COG2222	sugar isomerase
CXX03_RS17580	COG1082	Xylose isomerase domain protein TIM barrel
CXX03_RS17590	COG2188	Transcriptional regulator
CXX03_RS17595	COG0626	cystathionine gamma-synthase activity
CXX03_RS17610	COG1735	metal-dependent hydrolase with the TIM-barrel fold
CXX03_RS17615	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CXX03_RS17620	COG3457	Alanine racemase
CXX03_RS17630	COG2188	Transcriptional regulator
CXX03_RS17635	COG0180	Tryptophanyl-tRNA synthetase
CXX03_RS17640	COG0546	phosphoglycolate phosphatase activity
CXX03_RS17645	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CXX03_RS17650	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CXX03_RS17655	COG3266	domain, Protein
CXX03_RS17670	COG4796	Type ii and iii secretion system protein
CXX03_RS17685	COG3166	PFAM Fimbrial assembly family protein
CXX03_RS17690	COG4972	Pilus assembly protein
CXX03_RS17695	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CXX03_RS17700	COG0494	nUDIX hydrolase
CXX03_RS17710	COG1011	Hydrolase
CXX03_RS17715	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CXX03_RS17725	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CXX03_RS17755	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CXX03_RS17760	COG2183	response to ionizing radiation
CXX03_RS17765	COG1918	ferrous iron import across plasma membrane
CXX03_RS17770	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CXX03_RS17780	COG5464	transposase or invertase
CXX03_RS17800	COG2610	gluconate transmembrane transporter activity
CXX03_RS17805	COG1640	4-alpha-glucanotransferase
CXX03_RS17810	COG0058	SHG alpha-glucan phosphorylase activity
CXX03_RS17825	COG1690	Belongs to the RtcB family
CXX03_RS17830	COG4650	regulator
CXX03_RS17835	COG1349	DNA-binding transcription factor activity
CXX03_RS17850	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CXX03_RS17870	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CXX03_RS17875	COG0058	SHG alpha-glucan phosphorylase activity
CXX03_RS17900	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CXX03_RS17905	COG2095	MarC family integral membrane protein
CXX03_RS17910	COG2610	gluconate transmembrane transporter activity
CXX03_RS17915	COG3265	gluconokinase activity
CXX03_RS17920	COG1609	Transcriptional regulator
CXX03_RS17925	COG1741	Belongs to the pirin family
CXX03_RS17930	COG0673	inositol 2-dehydrogenase activity
CXX03_RS17935	COG1247	-acetyltransferase
CXX03_RS17940	COG3157	Type VI secretion system effector, Hcp
CXX03_RS17960	COG0405	Gamma-glutamyltransferase
CXX03_RS17970	COG0584	glycerophosphoryl diester phosphodiesterase
CXX03_RS17975	COG3842	ATPase activity
CXX03_RS17985	COG1175	transmembrane transport
CXX03_RS17990	COG1653	transport
CXX03_RS17995	COG0410	ABC transporter
CXX03_RS18000	COG0411	ABC transporter
CXX03_RS18005	COG4177	L-phenylalanine transmembrane transporter activity
CXX03_RS18010	COG0559	Belongs to the binding-protein-dependent transport system permease family
CXX03_RS18015	COG0683	leucine binding
CXX03_RS18020	COG0456	acetyltransferase
CXX03_RS18025	COG0683	leucine binding
CXX03_RS18030	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CXX03_RS18035	COG2177	Part of the ABC transporter FtsEX involved in
CXX03_RS18040	COG2884	Cell division ATP-binding protein ftsE
CXX03_RS18045	COG0552	protein localization to endoplasmic reticulum
CXX03_RS18050	COG0742	ribosomal rna small subunit methyltransferase
CXX03_RS18055	COG3776	membrane
CXX03_RS18065	COG3714	YhhN family
CXX03_RS18080	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CXX03_RS18095	COG0628	permease
CXX03_RS18100	COG2091	lysine biosynthetic process via aminoadipic acid
CXX03_RS18105	COG0747	negative chemotaxis
CXX03_RS18110	COG0601	transmembrane transport
CXX03_RS18115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CXX03_RS18120	COG0444	Belongs to the ABC transporter superfamily
CXX03_RS18135	COG3209	COG3209 Rhs family protein
CXX03_RS18145	COG1413	lyase activity
CXX03_RS18150	COG5433	transposase activity
CXX03_RS18155	COG0842	Transport permease protein
CXX03_RS18160	COG1129	ABC transporter
CXX03_RS18160	COG0842	Transport permease protein
CXX03_RS18165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CXX03_RS18195	COG2081	HI0933 family
CXX03_RS18200	COG0306	phosphate transporter
CXX03_RS18210	COG0589	response to stress
CXX03_RS18220	COG3104	oligopeptide transport
CXX03_RS18230	COG0339	signal peptide processing
CXX03_RS18235	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CXX03_RS18240	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CXX03_RS18250	COG0640	Transcriptional regulator
CXX03_RS18255	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CXX03_RS18260	COG1393	Belongs to the ArsC family
CXX03_RS18280	COG3065	identical protein binding
CXX03_RS18285	COG2197	response regulator
CXX03_RS18290	COG1285	pathogenesis
CXX03_RS18305	COG3247	response to pH
CXX03_RS18310	COG2771	luxR family
CXX03_RS18320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CXX03_RS18325	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CXX03_RS18330	COG2207	Transcriptional regulator
CXX03_RS18340	COG0076	glutamate decarboxylase activity
CXX03_RS18345	COG1858	cytochrome C peroxidase
CXX03_RS18355	COG2197	response regulator
CXX03_RS18360	COG0583	DNA-binding transcription factor activity
CXX03_RS18365	COG1295	ribonuclease BN
CXX03_RS18370	COG0477	Major facilitator Superfamily
CXX03_RS18375	COG2982	Protein involved in outer membrane biogenesis
CXX03_RS18380	COG2200	EAL domain
CXX03_RS18390	COG0612	Peptidase, M16
CXX03_RS18400	COG2199	diguanylate cyclase activity
CXX03_RS18400	COG2200	EAL domain
CXX03_RS18405	COG3118	belongs to the thioredoxin family
CXX03_RS18405	COG0457	Tetratricopeptide repeat
CXX03_RS18410	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CXX03_RS18415	COG1215	transferase activity, transferring glycosyl groups
CXX03_RS18420	COG1215	transferase activity, transferring glycosyl groups
CXX03_RS18445	COG2194	sulfuric ester hydrolase activity
CXX03_RS18460	COG0814	amino acid
CXX03_RS18465	COG4608	Belongs to the ABC transporter superfamily
CXX03_RS18470	COG0444	Belongs to the ABC transporter superfamily
CXX03_RS18475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CXX03_RS18480	COG0601	transmembrane transport
CXX03_RS18490	COG0747	negative chemotaxis
CXX03_RS18500	COG3547	Transposase (IS116 IS110 IS902 family)
CXX03_RS18515	COG2194	sulfuric ester hydrolase activity
CXX03_RS18520	COG2223	nitrite transmembrane transporter activity
CXX03_RS18525	COG5571	outer membrane autotransporter
CXX03_RS18530	COG2818	Glycosylase
CXX03_RS18535	COG0456	acetyltransferase
CXX03_RS18540	COG0243	molybdopterin cofactor binding
CXX03_RS18545	COG2885	chlorophyll binding
CXX03_RS18560	COG2944	sequence-specific DNA binding
CXX03_RS18565	COG1278	Cold shock
CXX03_RS18590	COG3274	enterobacterial common antigen metabolic process
CXX03_RS18595	COG4682	membrane
CXX03_RS18600	COG4682	membrane
CXX03_RS18605	COG1070	Carbohydrate kinase
CXX03_RS18615	COG4213	ABC transporter substrate-binding protein
CXX03_RS18620	COG1129	ABC transporter
CXX03_RS18625	COG4214	carbohydrate transport
CXX03_RS18630	COG2207	Transcriptional regulator
CXX03_RS18630	COG1609	Transcriptional regulator
CXX03_RS18635	COG2992	FlgJ-related protein
CXX03_RS18640	COG0366	Alpha amylase catalytic
CXX03_RS18645	COG3977	Valine--pyruvate aminotransferase
CXX03_RS18650	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CXX03_RS18655	COG1414	Transcriptional regulator
CXX03_RS18665	COG2731	YhcH YjgK YiaL family protein
CXX03_RS18670	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CXX03_RS18675	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CXX03_RS18680	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CXX03_RS18685	COG1070	Carbohydrate kinase
CXX03_RS18690	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CXX03_RS18695	COG3623	hexulose-6-phosphate isomerase
CXX03_RS18700	COG0235	Class ii aldolase
CXX03_RS18710	COG3713	MltA-interacting MipA family protein
CXX03_RS18715	COG0583	DNA-binding transcription factor activity
CXX03_RS18720	COG1566	PFAM secretion protein HlyD family protein
CXX03_RS18735	COG1012	belongs to the aldehyde dehydrogenase family
CXX03_RS18740	COG1454	alcohol dehydrogenase
CXX03_RS18745	COG3276	selenocysteine insertion sequence binding
CXX03_RS18755	COG0625	glutathione transferase activity
CXX03_RS18760	COG3209	COG3209 Rhs family protein
CXX03_RS18770	COG1413	lyase activity
CXX03_RS18780	COG3209	COG3209 Rhs family protein
CXX03_RS18785	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CXX03_RS18805	COG1566	PFAM secretion protein HlyD family protein
CXX03_RS18815	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX03_RS18815	COG2213	PTS system mannitol-specific
CXX03_RS18825	COG3722	fumarate hydratase activity
CXX03_RS18850	COG5295	Hep Hag repeat protein
CXX03_RS18855	COG1620	l-lactate permease
CXX03_RS18860	COG2186	Transcriptional regulator
CXX03_RS18870	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CXX03_RS18875	COG1045	serine acetyltransferase
CXX03_RS18890	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CXX03_RS18895	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CXX03_RS18910	COG4942	peptidase
CXX03_RS18915	COG2861	carbohydrate metabolic process
CXX03_RS18920	COG1216	Glycosyl transferase, family 2
CXX03_RS18930	COG0156	8-amino-7-oxononanoate synthase activity
CXX03_RS18940	COG0859	PFAM glycosyl transferase family 9
CXX03_RS18945	COG0859	PFAM glycosyl transferase family 9
CXX03_RS18960	COG1442	glycosyl transferase family 8
CXX03_RS18965	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CXX03_RS18980	COG0515	serine threonine protein kinase
CXX03_RS18985	COG0438	transferase activity, transferring glycosyl groups
CXX03_RS18990	COG0859	PFAM glycosyl transferase family 9
CXX03_RS18995	COG1519	Transferase
CXX03_RS19025	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CXX03_RS19050	COG1561	YicC-like family, N-terminal region
CXX03_RS19055	COG3645	SOS response
CXX03_RS19060	COG2860	membrane
CXX03_RS19070	COG0194	GDP metabolic process
CXX03_RS19080	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CXX03_RS19085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CXX03_RS19090	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CXX03_RS19100	COG0786	glutamate:sodium symporter activity
CXX03_RS19105	COG2233	PERMEase
CXX03_RS19110	COG2982	Protein involved in outer membrane biogenesis
CXX03_RS19115	COG1501	Belongs to the glycosyl hydrolase 31 family
CXX03_RS19120	COG2211	Major facilitator Superfamily
CXX03_RS19130	COG0582	viral genome integration into host DNA
CXX03_RS19160	COG2378	regulation of single-species biofilm formation
CXX03_RS19165	COG3596	GTP binding
CXX03_RS19210	COG2003	Belongs to the UPF0758 family
CXX03_RS19250	COG2814	Major facilitator Superfamily
CXX03_RS19255	COG0697	spore germination
CXX03_RS19260	COG1464	Belongs to the NlpA lipoprotein family
CXX03_RS19280	COG2252	PERMEase
CXX03_RS19290	COG2271	Major facilitator Superfamily
CXX03_RS19295	COG2271	Major facilitator Superfamily
CXX03_RS19300	COG3851	Histidine kinase
CXX03_RS19305	COG2197	response regulator
CXX03_RS19310	COG0440	acetolactate synthase activity
CXX03_RS19315	COG0028	Belongs to the TPP enzyme family
CXX03_RS19330	COG2814	Major facilitator Superfamily
CXX03_RS19335	COG0641	radical SAM
CXX03_RS19345	COG2149	membrane
CXX03_RS19355	COG3119	arylsulfatase activity
CXX03_RS19360	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CXX03_RS19365	COG2207	Transcriptional regulator
CXX03_RS19380	COG2188	Transcriptional regulator
CXX03_RS19400	COG5645	(Lipo)protein
CXX03_RS19405	COG0823	Involved in the tonB-independent uptake of proteins
CXX03_RS19415	COG2271	Major facilitator Superfamily
CXX03_RS19425	COG0800	Aldolase
CXX03_RS19430	COG3734	2-keto-3-deoxy-galactonokinase
CXX03_RS19435	COG2186	Transcriptional regulator
CXX03_RS19445	COG0561	phosphatase activity
CXX03_RS19450	COG3753	Protein conserved in bacteria
CXX03_RS19455	COG0187	DNA topoisomerase II activity
CXX03_RS19465	COG0592	DNA-directed DNA polymerase activity
CXX03_RS19515	COG0814	amino acid
CXX03_RS19530	COG2091	lysine biosynthetic process via aminoadipic acid
CXX03_RS19535	COG0431	NADPH-dependent FMN reductase
CXX03_RS19540	COG2252	PERMEase
CXX03_RS19545	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CXX03_RS19565	COG3196	Protein conserved in bacteria
CXX03_RS19570	COG0363	glucosamine-6-phosphate deaminase activity
CXX03_RS19575	COG2382	esterase
CXX03_RS19585	COG2723	6-phospho-beta-galactosidase activity
CXX03_RS19590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXX03_RS19590	COG2190	(PTS) system
CXX03_RS19590	COG1263	PTS System
CXX03_RS19595	COG3711	transcriptional antiterminator
CXX03_RS19600	COG0704	Plays a role in the regulation of phosphate uptake
CXX03_RS19605	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CXX03_RS19610	COG0581	inorganic phosphate transmembrane transporter activity
CXX03_RS19615	COG0573	inorganic phosphate transmembrane transporter activity
CXX03_RS19620	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CXX03_RS19635	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CXX03_RS19690	COG3312	ion transport
CXX03_RS19705	COG0716	FMN binding
CXX03_RS19710	COG1522	sequence-specific DNA binding
CXX03_RS19740	COG1129	ABC transporter
CXX03_RS19745	COG1172	Belongs to the binding-protein-dependent transport system permease family
CXX03_RS19750	COG1879	ABC-type sugar transport system periplasmic component
CXX03_RS19755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CXX03_RS19760	COG1609	Transcriptional regulator
CXX03_RS19765	COG0477	Major facilitator Superfamily
CXX03_RS19770	COG2186	Transcriptional regulator
CXX03_RS19810	COG3085	chromosome segregation
CXX03_RS19815	COG0606	chelatase, subunit chli
CXX03_RS19835	COG3978	acetolactate synthase activity
CXX03_RS19840	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CXX03_RS19850	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CXX03_RS19855	COG0583	DNA-binding transcription factor activity
CXX03_RS19865	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CXX03_RS19870	COG3692	DNA binding
CXX03_RS19875	COG0210	DNA helicase
CXX03_RS19890	COG3118	belongs to the thioredoxin family
CXX03_RS19900	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CXX03_RS19905	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CXX03_RS19910	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CXX03_RS19915	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CXX03_RS19920	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CXX03_RS19925	COG1088	dTDP-glucose 4,6-dehydratase activity
CXX03_RS19930	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CXX03_RS19935	COG0456	acetyltransferase
CXX03_RS19940	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CXX03_RS19945	COG2244	polysaccharide biosynthetic process
CXX03_RS19965	COG1113	amino acid transport
CXX03_RS19990	COG0641	radical SAM
CXX03_RS19995	COG3071	HemY protein
CXX03_RS20000	COG2959	enzyme of heme biosynthesis
CXX03_RS20005	COG1587	Uroporphyrinogen-III synthase
CXX03_RS20015	COG3072	Adenylate cyclase
CXX03_RS20040	COG5567	small periplasmic lipoprotein
CXX03_RS20050	COG3159	Protein conserved in bacteria
CXX03_RS20060	COG1011	Hydrolase
CXX03_RS20065	COG0210	DNA helicase
CXX03_RS20070	COG3698	Phosphodiester glycosidase
CXX03_RS20075	COG0598	Magnesium transport protein CorA
CXX03_RS20105	COG2962	Rard protein
CXX03_RS20110	COG2050	protein possibly involved in aromatic compounds catabolism
CXX03_RS20115	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
CXX03_RS20120	COG0514	ATP-dependent DNA helicase (RecQ)
CXX03_RS20125	COG1280	lysine exporter protein (LysE YggA)
CXX03_RS20130	COG1280	lysine exporter protein (LysE YggA)
CXX03_RS20135	COG2267	carboxylic ester hydrolase activity
CXX03_RS20140	COG0561	phosphatase activity
CXX03_RS20145	COG0697	spore germination
CXX03_RS20150	COG0583	DNA-binding transcription factor activity
CXX03_RS20160	COG0412	Dienelactone hydrolase
CXX03_RS20165	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CXX03_RS20170	COG1322	Protein conserved in bacteria
CXX03_RS20180	COG3165	ubiquinone biosynthetic process from chorismate
CXX03_RS20190	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CXX03_RS20195	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CXX03_RS20200	COG0805	protein transport
CXX03_RS20210	COG0250	Participates in transcription elongation, termination and antitermination
CXX03_RS20215	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CXX03_RS20220	COG0543	2 iron, 2 sulfur cluster binding
CXX03_RS20240	COG1739	Uncharacterized protein family UPF0029
CXX03_RS20245	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CXX03_RS20250	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CXX03_RS20280	COG1763	Mo-molybdopterin cofactor biosynthetic process
CXX03_RS20285	COG0746	molybdenum cofactor guanylyltransferase activity
CXX03_RS20290	COG3084	Protein conserved in bacteria
CXX03_RS20295	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CXX03_RS20300	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CXX03_RS20305	COG5339	Protein conserved in bacteria
CXX03_RS20310	COG0204	Acyl-transferase
CXX03_RS20320	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CXX03_RS20320	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CXX03_RS20335	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CXX03_RS20345	COG2204	response regulator
CXX03_RS20350	COG3852	Histidine kinase
CXX03_RS20355	COG0174	glutamine synthetase
CXX03_RS20360	COG1217	gtp-binding protein TYPA
CXX03_RS20365	COG2188	Transcriptional regulator
CXX03_RS20370	COG1082	Xylose isomerase domain protein TIM barrel
CXX03_RS20375	COG2271	Major facilitator Superfamily
CXX03_RS20380	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CXX03_RS20385	COG2211	Major facilitator Superfamily
CXX03_RS20395	COG1501	Belongs to the glycosyl hydrolase 31 family
CXX03_RS20400	COG2017	converts alpha-aldose to the beta-anomer
CXX03_RS20405	COG2942	2-epimerase
CXX03_RS20410	COG3684	Belongs to the aldolase LacD family
CXX03_RS20420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CXX03_RS20425	COG1349	DNA-binding transcription factor activity
CXX03_RS20430	COG1011	Hydrolase
CXX03_RS20445	COG0456	acetyltransferase
CXX03_RS20455	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
CXX03_RS20465	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CXX03_RS20470	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CXX03_RS20480	COG2864	formate dehydrogenase
CXX03_RS20485	COG0437	4 iron, 4 sulfur cluster binding
CXX03_RS20505	COG3711	transcriptional antiterminator
CXX03_RS20505	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX03_RS20510	COG1363	Peptidase, m42
CXX03_RS20515	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CXX03_RS20515	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CXX03_RS20520	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX03_RS20560	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CXX03_RS20570	COG2258	MOSC domain
CXX03_RS20575	COG2205	protein histidine kinase activity
CXX03_RS20580	COG0745	RESPONSE REGULATOR receiver
CXX03_RS20585	COG3678	ATP-independent chaperone mediated protein folding
CXX03_RS20600	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CXX03_RS20620	COG3152	Membrane
CXX03_RS20625	COG3691	Protein conserved in bacteria
CXX03_RS20630	COG0589	response to stress
CXX03_RS20640	COG1494	fructose-1,6-bisphosphatase
CXX03_RS20650	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CXX03_RS20665	COG1575	Belongs to the MenA family. Type 1 subfamily
CXX03_RS20680	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CXX03_RS20685	COG1609	Transcriptional regulator
CXX03_RS20690	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CXX03_RS20700	COG3209	COG3209 Rhs family protein
CXX03_RS20710	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
CXX03_RS20720	COG0626	cystathionine gamma-synthase activity
CXX03_RS20725	COG0460	homoserine dehydrogenase
CXX03_RS20725	COG0527	aspartate kinase activity
CXX03_RS20730	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CXX03_RS20740	COG0697	spore germination
CXX03_RS20745	COG3738	Protein conserved in bacteria
CXX03_RS20750	COG0371	Dehydrogenase
CXX03_RS20755	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CXX03_RS20760	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX03_RS20760	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CXX03_RS20760	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX03_RS20765	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CXX03_RS20770	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CXX03_RS20775	COG1882	Formate acetyltransferase
CXX03_RS20780	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CXX03_RS20785	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CXX03_RS20790	COG2207	Transcriptional regulator
CXX03_RS20795	COG2194	sulfuric ester hydrolase activity
CXX03_RS20810	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CXX03_RS20830	COG4948	Mandelate Racemase Muconate Lactonizing
CXX03_RS20835	COG2271	Major facilitator Superfamily
CXX03_RS20840	COG0583	DNA-binding transcription factor activity
CXX03_RS20850	COG1309	transcriptional regulator
CXX03_RS20865	COG4206	TonB-dependent receptor
CXX03_RS20900	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CXX03_RS20900	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CXX03_RS20935	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CXX03_RS20940	COG0250	Participates in transcription elongation, termination and antitermination
CXX03_RS20980	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CXX03_RS20990	COG2104	thiamine diphosphate biosynthetic process
CXX03_RS20995	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CXX03_RS21030	COG3068	Protein conserved in bacteria
CXX03_RS21045	COG3678	ATP-independent chaperone mediated protein folding
CXX03_RS21050	COG4191	Histidine kinase
CXX03_RS21055	COG2204	response regulator
CXX03_RS21060	COG0151	Belongs to the GarS family
CXX03_RS21090	COG0456	acetyltransferase
CXX03_RS21100	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CXX03_RS21105	COG2224	Isocitrate lyase
CXX03_RS21120	COG1414	Transcriptional regulator
CXX03_RS21125	COG1410	methionine synthase
CXX03_RS21125	COG0646	methionine synthase
CXX03_RS21130	COG1283	sodium-dependent phosphate transmembrane transporter activity
CXX03_RS21140	COG1187	pseudouridine synthase activity
CXX03_RS21155	COG3541	Predicted nucleotidyltransferase
CXX03_RS21160	COG0542	response to heat
CXX03_RS21165	COG0527	aspartate kinase activity
CXX03_RS21195	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CXX03_RS21210	COG0477	Major facilitator Superfamily
CXX03_RS21210	COG2814	Major facilitator Superfamily
CXX03_RS21215	COG3833	ABC-type maltose transport systems, permease component
CXX03_RS21220	COG1175	transmembrane transport
CXX03_RS21225	COG2182	Extracellular solute-binding protein
CXX03_RS21230	COG3842	ATPase activity
CXX03_RS21265	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CXX03_RS21275	COG0534	Mate efflux family protein
CXX03_RS21280	COG3237	CsbD-like
CXX03_RS21285	COG0735	belongs to the Fur family
CXX03_RS21300	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CXX03_RS21310	COG0604	alcohol dehydrogenase
CXX03_RS21315	COG0305	Participates in initiation and elongation during chromosome replication
CXX03_RS21320	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CXX03_RS21325	COG1448	Aminotransferase
CXX03_RS21335	COG3700	Belongs to the class B bacterial acid phosphatase family
CXX03_RS21340	COG0432	Pfam Uncharacterised protein family UPF0047
CXX03_RS21345	COG2315	Protein conserved in bacteria
CXX03_RS21350	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CXX03_RS21355	COG0629	single-stranded DNA binding
CXX03_RS21365	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CXX03_RS21370	COG2207	Transcriptional regulator
CXX03_RS21375	COG0789	Transcriptional regulator
CXX03_RS21380	COG2252	PERMEase
CXX03_RS21385	COG0025	NhaP-type Na H and K H
CXX03_RS21390	COG1357	PFAM Pentapeptide repeats (8 copies)
CXX03_RS21400	COG3162	membrane
CXX03_RS21405	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CXX03_RS21415	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CXX03_RS21420	COG0437	4 iron, 4 sulfur cluster binding
CXX03_RS21425	COG3301	Polysulphide reductase, NrfD
CXX03_RS21430	COG1138	Cytochrome C-type biogenesis protein
CXX03_RS21435	COG3088	subunit of a heme lyase
CXX03_RS21440	COG4235	cytochrome complex assembly
CXX03_RS21445	COG1301	dicarboxylic acid transport
CXX03_RS21450	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CXX03_RS21465	COG1289	transmembrane transporter activity
CXX03_RS21470	COG1566	PFAM secretion protein HlyD family protein
CXX03_RS21480	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CXX03_RS21485	COG1940	carbohydrate kinase activity
CXX03_RS21490	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CXX03_RS21495	COG1172	Belongs to the binding-protein-dependent transport system permease family
CXX03_RS21500	COG1129	ABC transporter
CXX03_RS21505	COG1879	ABC-type sugar transport system periplasmic component
CXX03_RS21510	COG1737	Transcriptional regulator
CXX03_RS21515	COG0698	ribose 5-phosphate isomerase
CXX03_RS21525	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CXX03_RS21530	COG0456	acetyltransferase
CXX03_RS21535	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CXX03_RS21540	COG3454	Phosphonate metabolism
CXX03_RS21545	COG4778	phosphonate C-P lyase system protein PhnL
CXX03_RS21550	COG4107	phosphonate C-P lyase system protein PhnK
CXX03_RS21555	COG3627	carbon phosphorus lyase activity
CXX03_RS21560	COG3626	phosphonate metabolism
CXX03_RS21565	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CXX03_RS21570	COG3624	Phosphonate C-P lyase system protein PhnG
CXX03_RS21575	COG2188	Transcriptional regulator
CXX03_RS21580	COG3639	organic phosphonate transmembrane transporter activity
CXX03_RS21585	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CXX03_RS21595	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CXX03_RS21600	COG2824	Alkylphosphonate utilization operon protein PhnA
CXX03_RS21630	COG0477	Major facilitator Superfamily
CXX03_RS21640	COG0642	Histidine kinase
CXX03_RS21645	COG0745	RESPONSE REGULATOR receiver
CXX03_RS21650	COG2194	sulfuric ester hydrolase activity
CXX03_RS21655	COG0531	amino acid
CXX03_RS21660	COG2207	Transcriptional regulator
CXX03_RS21665	COG1982	Orn Lys Arg decarboxylase major
CXX03_RS21670	COG2169	Transcriptional regulator
CXX03_RS21675	COG1486	melibiose metabolic process
CXX03_RS21690	COG2211	Major facilitator Superfamily
CXX03_RS21700	COG3647	Membrane
CXX03_RS21705	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CXX03_RS21705	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CXX03_RS21710	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CXX03_RS21715	COG4565	transcriptional regulatory protein
CXX03_RS21720	COG3290	protein histidine kinase activity
CXX03_RS21725	COG3592	Divergent 4Fe-4S mono-cluster
CXX03_RS21730	COG2388	GCN5-related N-acetyl-transferase
CXX03_RS21745	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CXX03_RS21750	COG3104	oligopeptide transport
CXX03_RS21760	COG0531	amino acid
CXX03_RS21765	COG3030	protein affecting phage T7 exclusion by the F plasmid
CXX03_RS21770	COG1027	Aspartate ammonia-lyase
CXX03_RS21775	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CXX03_RS21790	COG1309	transcriptional regulator
CXX03_RS21800	COG3710	Transcriptional regulator
CXX03_RS21805	COG0531	amino acid
CXX03_RS21810	COG1982	Orn Lys Arg decarboxylase major
CXX03_RS21815	COG3104	oligopeptide transport
CXX03_RS21845	COG3547	Transposase (IS116 IS110 IS902 family)
CXX03_RS21855	COG1509	lysine 2,3-aminomutase activity
CXX03_RS21865	COG5510	response to toxic substance
CXX03_RS21870	COG5510	response to toxic substance
CXX03_RS21875	COG2076	Multidrug Resistance protein
CXX03_RS21880	COG3040	lipid binding
CXX03_RS21885	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CXX03_RS21900	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CXX03_RS21905	COG1053	succinate dehydrogenase
CXX03_RS21915	COG0531	amino acid
CXX03_RS21920	COG1511	domain protein
CXX03_RS21920	COG3264	Mechanosensitive ion channel
CXX03_RS21960	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CXX03_RS21965	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CXX03_RS21965	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CXX03_RS21970	COG0802	atpase or kinase
CXX03_RS21975	COG0860	N-Acetylmuramoyl-L-alanine amidase
CXX03_RS21995	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CXX03_RS22000	COG0330	HflC and HflK could
CXX03_RS22005	COG0330	HflC and HflK could
CXX03_RS22010	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CXX03_RS22025	COG0557	exoribonuclease II activity
CXX03_RS22030	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CXX03_RS22035	COG3789	protein conserved in bacteria
CXX03_RS22040	COG1842	Phage shock protein A
CXX03_RS22050	COG3766	membrane
CXX03_RS22055	COG5463	Belongs to the UPF0441 family
CXX03_RS22060	COG0754	glutathionylspermidine amidase activity
CXX03_RS22065	COG1960	acyl-CoA dehydrogenase activity
CXX03_RS22075	COG3650	response to hydrogen peroxide
CXX03_RS22080	COG1073	alpha beta
CXX03_RS22095	COG3037	sugar-specific permease SgaT UlaA
CXX03_RS22100	COG3414	Phosphotransferase system galactitol-specific IIB component
CXX03_RS22105	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX03_RS22140	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CXX03_RS22150	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CXX03_RS22160	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CXX03_RS22165	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CXX03_RS22170	COG4670	ketone body catabolic process
CXX03_RS22175	COG1024	Enoyl-CoA hydratase
CXX03_RS22190	COG1309	transcriptional regulator
CXX03_RS22195	COG3061	Opacity-associated protein A
CXX03_RS22200	COG0545	Peptidyl-prolyl cis-trans isomerase
CXX03_RS22205	COG1113	amino acid transport
CXX03_RS22215	COG0697	spore germination
CXX03_RS22220	COG0702	epimerase
CXX03_RS22225	COG1733	regulation of RNA biosynthetic process
CXX03_RS22230	COG0737	Belongs to the 5'-nucleotidase family
CXX03_RS22235	COG1218	3'(2'),5'-bisphosphate nucleotidase
CXX03_RS22240	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CXX03_RS22250	COG1253	flavin adenine dinucleotide binding
CXX03_RS22260	COG3547	Transposase (IS116 IS110 IS902 family)
CXX03_RS22265	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CXX03_RS22275	COG1609	Transcriptional regulator
CXX03_RS22280	COG1263	PTS System
CXX03_RS22280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXX03_RS22285	COG0366	Alpha amylase catalytic
CXX03_RS22290	COG1328	CTP reductase activity
CXX03_RS22295	COG0602	queuosine metabolic process
CXX03_RS22300	COG3783	Cytochrome b(562)
CXX03_RS22305	COG0312	modulator of DNA gyrase
CXX03_RS22315	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CXX03_RS22325	COG1172	Belongs to the binding-protein-dependent transport system permease family
CXX03_RS22330	COG1172	Belongs to the binding-protein-dependent transport system permease family
CXX03_RS22335	COG1129	ABC transporter
CXX03_RS22340	COG1879	ABC-type sugar transport system periplasmic component
CXX03_RS22345	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CXX03_RS22350	COG2337	Toxic component of a toxin-antitoxin (TA) module
CXX03_RS22355	COG2336	PFAM SpoVT AbrB
CXX03_RS22360	COG2105	PFAM AIG2 family protein
CXX03_RS22365	COG2911	Protein conserved in bacteria
CXX03_RS22370	COG0729	surface antigen
CXX03_RS22380	COG3547	Transposase (IS116 IS110 IS902 family)
CXX03_RS22390	COG0251	oxidation-reduction process
CXX03_RS22410	COG0251	oxidation-reduction process
CXX03_RS22415	COG1028	Short-chain dehydrogenase reductase Sdr
CXX03_RS22420	COG1309	transcriptional regulator
CXX03_RS22425	COG2731	YhcH YjgK YiaL family protein
CXX03_RS22445	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
CXX03_RS22450	COG0456	acetyltransferase
CXX03_RS22455	COG4269	membrane
CXX03_RS22460	COG0525	valine-tRNA ligase activity
CXX03_RS22465	COG2927	DNA polymerase III (CHI subunit)
CXX03_RS22475	COG0795	lipopolysaccharide-transporting ATPase activity
CXX03_RS22480	COG0795	lipopolysaccharide-transporting ATPase activity
CXX03_RS22485	COG0433	COG0433 Predicted ATPase
CXX03_RS22490	COG1064	alcohol dehydrogenase
CXX03_RS22500	COG0582	viral genome integration into host DNA
CXX03_RS22505	COG0863	Belongs to the N(4) N(6)-methyltransferase family
CXX03_RS22645	COG0582	viral genome integration into host DNA
CXX03_RS22685	COG3188	usher protein
CXX03_RS22690	COG3539	Fimbrial protein
CXX03_RS22695	COG3539	Fimbrial protein
CXX03_RS22700	COG3539	Fimbrial protein
CXX03_RS22705	COG2610	gluconate transmembrane transporter activity
CXX03_RS22715	COG0246	Mannitol dehydrogenase
CXX03_RS22720	COG2186	Transcriptional regulator
CXX03_RS22740	COG0583	DNA-binding transcription factor activity
CXX03_RS22745	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CXX03_RS22750	COG0700	Nucleoside recognition
CXX03_RS22755	COG3366	ferrous iron transmembrane transporter activity
CXX03_RS22765	COG0477	Major facilitator Superfamily
CXX03_RS22780	COG1924	4 iron, 4 sulfur cluster binding
CXX03_RS22785	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
CXX03_RS22790	COG2733	membrane
CXX03_RS22795	COG2814	Major facilitator Superfamily
CXX03_RS22810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CXX03_RS22815	COG5457	Domain of unknown function (DUF1127)
CXX03_RS22825	COG0523	cobalamin synthesis protein
CXX03_RS22830	COG2879	small protein
CXX03_RS22835	COG1966	Carbon starvation protein
CXX03_RS22840	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CXX03_RS22845	COG2368	4-hydroxyphenylacetate
CXX03_RS22865	COG3971	2-oxopent-4-enoate hydratase activity
CXX03_RS22875	COG3384	dioxygenase
CXX03_RS22880	COG1012	belongs to the aldehyde dehydrogenase family
CXX03_RS22885	COG0179	Fumarylacetoacetate (FAA) hydrolase
CXX03_RS22890	COG1846	Transcriptional regulator
CXX03_RS22895	COG0840	transmembrane signaling receptor activity
CXX03_RS22900	COG2271	Major facilitator Superfamily
CXX03_RS22905	COG1802	Transcriptional regulator
CXX03_RS22910	COG1063	alcohol dehydrogenase
CXX03_RS22925	COG1484	DNA-dependent DNA replication
CXX03_RS22940	COG2966	Psort location CytoplasmicMembrane, score
CXX03_RS22950	COG2197	response regulator
CXX03_RS22955	COG4114	ferric iron reductase
CXX03_RS22985	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CXX03_RS22990	COG0456	acetyltransferase
CXX03_RS22995	COG1011	Hydrolase
CXX03_RS23005	COG2823	Periplasmic or secreted lipoprotein
CXX03_RS23015	COG4667	esterase of the alpha-beta hydrolase superfamily
CXX03_RS23020	COG0084	hydrolase, TatD family'
CXX03_RS23025	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CXX03_RS23030	COG1328	CTP reductase activity
CXX03_RS23060	COG3726	membrane protein affecting hemolysin expression
CXX03_RS23065	COG0560	Phosphoserine phosphatase
CXX03_RS23070	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CXX03_RS23075	COG3172	ATPase kinase involved in NAD metabolism
CXX03_RS23075	COG1056	cytidyltransferase-related domain
CXX03_RS23080	COG0488	(ABC) transporter
CXX03_RS23085	COG0741	lytic transglycosylase activity
CXX03_RS23095	COG3547	Transposase (IS116 IS110 IS902 family)
CXX03_RS23115	COG2207	Transcriptional regulator
CXX03_RS23115	COG3708	Transcriptional regulator
CXX03_RS23120	COG3045	CreA protein
CXX03_RS23125	COG0745	RESPONSE REGULATOR receiver
CXX03_RS23130	COG2205	protein histidine kinase activity
CXX03_RS23135	COG4452	Inner membrane protein CreD
CXX03_RS23140	COG0745	RESPONSE REGULATOR receiver
CXX03_RS23150	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CXX03_RS23160	COG0527	aspartate kinase activity
CXX03_RS23160	COG0460	homoserine dehydrogenase
CXX03_RS23170	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CXX03_RS23185	COG3547	Transposase (IS116 IS110 IS902 family)
CXX03_RS23195	COG1115	amino acid carrier protein
CXX03_RS23205	COG0521	Mo-molybdopterin cofactor biosynthetic process
CXX03_RS23210	COG1584	GPR1 FUN34 yaaH family protein
CXX03_RS23215	COG4735	regulation of single-species biofilm formation
CXX03_RS23245	COG0583	DNA-binding transcription factor activity
CXX03_RS23275	COG0196	riboflavin kinase activity
CXX03_RS23290	COG1047	Peptidyl-prolyl cis-trans
CXX03_RS23310	COG0505	Belongs to the CarA family
CXX03_RS23315	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CXX03_RS23365	COG0644	oxidoreductase
CXX03_RS23370	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CXX03_RS23375	COG2271	Major facilitator Superfamily
CXX03_RS23395	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CXX03_RS23435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CXX03_RS23440	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CXX03_RS23445	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CXX03_RS23450	COG0564	pseudouridine synthase activity
CXX03_RS23460	COG0417	DNA replication proofreading
CXX03_RS23465	COG0235	Class ii aldolase
CXX03_RS23480	COG4977	sequence-specific DNA binding
CXX03_RS23485	COG0586	Pfam SNARE associated Golgi protein
CXX03_RS23495	COG1178	ABC-type Fe3 transport system permease component
CXX03_RS23500	COG4143	(ABC) transporter
CXX03_RS23515	COG2814	Major facilitator Superfamily
CXX03_RS23530	COG0473	3-isopropylmalate dehydrogenase activity
CXX03_RS23545	COG0583	DNA-binding transcription factor activity
CXX03_RS23550	COG0028	Belongs to the TPP enzyme family
CXX03_RS23555	COG0440	acetolactate synthase activity
CXX03_RS23565	COG1609	Transcriptional regulator
CXX03_RS23580	COG3116	cell division
CXX03_RS23585	COG0768	penicillin binding
CXX03_RS23590	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CXX03_RS23595	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CXX03_RS23610	COG0772	Belongs to the SEDS family
CXX03_RS23625	COG1181	Belongs to the D-alanine--D-alanine ligase family
CXX03_RS23630	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CXX03_RS23635	COG0849	cell division
CXX03_RS23640	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CXX03_RS23660	COG0494	nUDIX hydrolase
CXX03_RS23675	COG0237	dephospho-CoA kinase activity
CXX03_RS23685	COG1459	type II secretion system
CXX03_RS23690	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CXX03_RS23695	COG4969	Belongs to the N-Me-Phe pilin family
CXX03_RS23700	COG0157	Belongs to the NadC ModD family
CXX03_RS23705	COG3023	N-Acetylmuramoyl-L-alanine amidase
CXX03_RS23710	COG3725	Membrane protein required for beta-lactamase induction
CXX03_RS23715	COG1113	amino acid transport
CXX03_RS23720	COG2186	Transcriptional regulator
CXX03_RS23725	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CXX03_RS23730	COG0508	dehydrogenase complex catalyzes the overall conversion of
CXX03_RS23735	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CXX03_RS23740	COG3064	Membrane
CXX03_RS23745	COG1049	propionate catabolic process, 2-methylcitrate cycle
CXX03_RS23770	COG2132	Multicopper oxidase
CXX03_RS23785	COG4993	Dehydrogenase
CXX03_RS23790	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CXX03_RS23795	COG0288	reversible hydration of carbon dioxide
CXX03_RS23800	COG1131	(ABC) transporter
CXX03_RS23805	COG0842	Transport permease protein
CXX03_RS23810	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX03_RS23815	COG0726	polysaccharide deacetylase
CXX03_RS23825	COG5464	transposase or invertase
CXX03_RS23840	COG3539	Fimbrial protein
CXX03_RS23845	COG3539	Fimbrial protein
CXX03_RS23850	COG3539	Fimbrial protein
CXX03_RS23855	COG3539	Fimbrial protein
CXX03_RS23860	COG3188	usher protein
CXX03_RS23865	COG3121	Chaperone
CXX03_RS23870	COG3539	Fimbrial protein
CXX03_RS23875	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CXX03_RS23880	COG0617	tRNA 3'-terminal CCA addition
CXX03_RS23890	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CXX03_RS23900	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CXX03_RS23905	COG1643	Atp-dependent helicase
CXX03_RS23910	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CXX03_RS23915	COG4774	siderophore transport
CXX03_RS23920	COG1120	ATPase activity
CXX03_RS23925	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CXX03_RS23930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CXX03_RS23955	COG2860	membrane
CXX03_RS23960	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CXX03_RS23975	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CXX03_RS23980	COG3835	regulator
CXX03_RS24000	COG0024	Methionine aminopeptidase
CXX03_RS24025	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CXX03_RS24030	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CXX03_RS24035	COG0575	Belongs to the CDS family
CXX03_RS24040	COG0750	zinc metalloprotease
CXX03_RS24050	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CXX03_RS24055	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CXX03_RS24080	COG0587	DNA-directed DNA polymerase activity
CXX03_RS24095	COG0346	lactoylglutathione lyase activity
CXX03_RS24105	COG4568	rho-dependent transcription termination
CXX03_RS24115	COG4681	YaeQ
CXX03_RS24120	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CXX03_RS24125	COG3015	lipoprotein NlpE involved in copper resistance
CXX03_RS24135	COG3547	Transposase (IS116 IS110 IS902 family)
CXX03_RS24140	COG0791	NLP P60 protein
CXX03_RS24150	COG1720	tRNA m6t6A37 methyltransferase activity
CXX03_RS24160	COG1464	Belongs to the NlpA lipoprotein family
CXX03_RS24165	COG2011	ABC-type metal ion transport system permease component
CXX03_RS24170	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CXX03_RS24360	COG4372	Transposase
CXX03_RS24365	COG3436	PFAM IS66 Orf2 family protein
CXX03_RS24450	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CXX03_RS24490	COG1136	(ABC) transporter
CXX03_RS24490	COG0577	efflux transmembrane transporter activity
CXX03_RS24685	COG1475	DNA binding
CXX03_RS24875	COG3436	PFAM IS66 Orf2 family protein
CXX03_RS24915	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CXX03_RS25145	COG3941	tape measure
CXX03_RS25190	COG4932	domain protein
CXX03_RS25190	COG5492	domain, Protein
CXX03_RS25235	COG1475	DNA binding
CXX03_RS25240	COG1475	DNA binding
CXX03_RS25335	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CXX03_RS25500	COG1278	Cold shock
CXX03_RS25705	COG1121	(ABC) transporter
CXX03_RS25745	COG1459	type II secretion system
CXX03_RS25750	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CXX03_RS25785	COG2165	general secretion pathway protein