locus-tag	class	description
EGM66_RS00090	COG3504	Conjugal transfer protein
EGM66_RS00145	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EGM66_RS00360	COG2003	Belongs to the UPF0758 family
EGM66_RS00390	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EGM66_RS00490	COG3344	reverse transcriptase
EGM66_RS00515	COG0583	DNA-binding transcription factor activity
EGM66_RS00785	COG1475	DNA binding
EGM66_RS00905	COG0675	Transposase, IS605 OrfB family
EGM66_RS01140	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EGM66_RS01145	COG0629	single-stranded DNA binding
EGM66_RS01395	COG0305	Participates in initiation and elongation during chromosome replication
EGM66_RS01435	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EGM66_RS01575	COG0741	lytic transglycosylase activity
EGM66_RS01635	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EGM66_RS01760	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EGM66_RS01775	COG0741	lytic transglycosylase activity
EGM66_RS01840	COG2805	Type II/IV secretion system protein
EGM66_RS01955	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EGM66_RS02120	COG1475	DNA binding
EGM66_RS02240	COG1823	symporter activity
EGM66_RS02255	COG1388	LysM domain
EGM66_RS02255	COG2373	Large extracellular alpha-helical protein
EGM66_RS02255	COG4932	domain protein
EGM66_RS02260	COG1388	LysM domain
EGM66_RS02260	COG1470	cell adhesion involved in biofilm formation
EGM66_RS02265	COG1388	LysM domain
EGM66_RS02265	COG1470	cell adhesion involved in biofilm formation
EGM66_RS02290	COG0477	Major facilitator Superfamily
EGM66_RS02295	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EGM66_RS02300	COG0217	transcriptional regulatory protein
EGM66_RS02310	COG0534	Mate efflux family protein
EGM66_RS02320	COG0583	DNA-binding transcription factor activity
EGM66_RS02325	COG0583	DNA-binding transcription factor activity
EGM66_RS02335	COG1376	ErfK ybiS ycfS ynhG family protein
EGM66_RS02350	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
EGM66_RS02390	COG1735	metal-dependent hydrolase with the TIM-barrel fold
EGM66_RS02535	COG2003	Belongs to the UPF0758 family
EGM66_RS02580	COG1289	transmembrane transporter activity
EGM66_RS02590	COG1686	Belongs to the peptidase S11 family
EGM66_RS02595	COG2925	Exonuclease
EGM66_RS02600	COG0425	Belongs to the sulfur carrier protein TusA family
EGM66_RS02605	COG2391	methyltransferase activity
EGM66_RS02610	COG0531	amino acid
EGM66_RS02620	COG0583	DNA-binding transcription factor activity
EGM66_RS02625	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGM66_RS02630	COG4115	mRNA cleavage
EGM66_RS02635	COG2161	toxin-antitoxin pair type II binding
EGM66_RS02660	COG0131	Imidazoleglycerol-phosphate dehydratase
EGM66_RS02660	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EGM66_RS02665	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EGM66_RS02690	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EGM66_RS02695	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EGM66_RS02715	COG1216	Glycosyl transferase, family 2
EGM66_RS02725	COG0438	transferase activity, transferring glycosyl groups
EGM66_RS02725	COG4641	Protein conserved in bacteria
EGM66_RS02740	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EGM66_RS02750	COG1088	dTDP-glucose 4,6-dehydratase activity
EGM66_RS02755	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EGM66_RS02760	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGM66_RS02770	COG0438	transferase activity, transferring glycosyl groups
EGM66_RS02775	COG2327	Polysaccharide pyruvyl transferase
EGM66_RS02780	COG2244	polysaccharide biosynthetic process
EGM66_RS02785	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EGM66_RS02790	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EGM66_RS02795	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
EGM66_RS02795	COG0662	Cupin 2, conserved barrel domain protein
EGM66_RS02800	COG0297	glycogen (starch) synthase activity
EGM66_RS02805	COG1051	belongs to the nudix hydrolase family
EGM66_RS02810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGM66_RS02815	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
EGM66_RS02820	COG0110	maltose O-acetyltransferase activity
EGM66_RS02825	COG1216	Glycosyl transferase, family 2
EGM66_RS02835	COG0438	transferase activity, transferring glycosyl groups
EGM66_RS02840	COG1045	serine acetyltransferase
EGM66_RS02845	COG0463	Glycosyl transferase, family 2
EGM66_RS02850	COG0489	protein tyrosine kinase activity
EGM66_RS02850	COG3206	protein involved in exopolysaccharide biosynthesis
EGM66_RS02855	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EGM66_RS02860	COG1596	polysaccharide export
EGM66_RS02865	COG1253	flavin adenine dinucleotide binding
EGM66_RS02870	COG2982	Protein involved in outer membrane biogenesis
EGM66_RS02880	COG0572	uridine kinase
EGM66_RS02885	COG3447	MASE1 domain protein
EGM66_RS02885	COG5002	protein histidine kinase activity
EGM66_RS02885	COG5001	Diguanylate cyclase
EGM66_RS02890	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EGM66_RS02895	COG0443	Heat shock 70 kDa protein
EGM66_RS02900	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
EGM66_RS02905	COG3779	Protein conserved in bacteria
EGM66_RS02910	COG0631	protein serine/threonine phosphatase activity
EGM66_RS02915	COG4245	von Willebrand factor, type A
EGM66_RS02955	COG2205	protein histidine kinase activity
EGM66_RS02960	COG0745	RESPONSE REGULATOR receiver
EGM66_RS02970	COG0826	peptidase U32
EGM66_RS03035	COG5301	cellulose 1,4-beta-cellobiosidase activity
EGM66_RS03035	COG5301	cellulose 1,4-beta-cellobiosidase activity
EGM66_RS03130	COG4695	Portal protein
EGM66_RS03195	COG4974	Belongs to the 'phage' integrase family
EGM66_RS03220	COG1063	alcohol dehydrogenase
EGM66_RS03225	COG3775	system Galactitol-specific IIC component
EGM66_RS03245	COG0786	glutamate:sodium symporter activity
EGM66_RS03260	COG0640	Transcriptional regulator
EGM66_RS03295	COG3436	PFAM IS66 Orf2 family protein
EGM66_RS03300	COG4372	Transposase
EGM66_RS03320	COG3414	Phosphotransferase system galactitol-specific IIB component
EGM66_RS03325	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGM66_RS03340	COG1830	Aldolase
EGM66_RS03345	COG2211	Major facilitator Superfamily
EGM66_RS03350	COG1397	ADP-ribosylglycohydrolase
EGM66_RS03355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGM66_RS03360	COG2188	Transcriptional regulator
EGM66_RS03365	COG3757	hydrolase, family 25
EGM66_RS03370	COG0351	phosphomethylpyrimidine kinase
EGM66_RS03390	COG5455	response to cobalt ion
EGM66_RS03395	COG3539	Fimbrial protein
EGM66_RS03400	COG3188	usher protein
EGM66_RS03405	COG3121	Chaperone
EGM66_RS03410	COG3539	Fimbrial protein
EGM66_RS03420	COG0489	protein tyrosine kinase activity
EGM66_RS03430	COG3831	ATPase activity
EGM66_RS03435	COG3831	ATPase activity
EGM66_RS03445	COG3552	Protein containing von Willebrand factor type A (VWA) domain
EGM66_RS03450	COG4715	Zinc finger, swim domain protein
EGM66_RS03455	COG4808	Protein conserved in bacteria
EGM66_RS03460	COG4807	Protein conserved in bacteria
EGM66_RS03465	COG3279	Response regulator of the LytR AlgR family
EGM66_RS03470	COG3275	phosphorelay sensor kinase activity
EGM66_RS03475	COG0789	Transcriptional regulator
EGM66_RS03485	COG1174	glycine betaine transport
EGM66_RS03490	COG1125	glycine betaine transport
EGM66_RS03495	COG1174	glycine betaine transport
EGM66_RS03500	COG1732	Glycine betaine
EGM66_RS03505	COG1472	Belongs to the glycosyl hydrolase 3 family
EGM66_RS03510	COG0277	FAD linked oxidase domain protein
EGM66_RS03515	COG1686	Belongs to the peptidase S11 family
EGM66_RS03525	COG0586	Pfam SNARE associated Golgi protein
EGM66_RS03530	COG1028	Short-chain dehydrogenase reductase Sdr
EGM66_RS03535	COG1538	Outer membrane efflux protein
EGM66_RS03545	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EGM66_RS03555	COG1346	cytolysis
EGM66_RS03565	COG2949	membrane
EGM66_RS03575	COG0493	'glutamate synthase
EGM66_RS03580	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EGM66_RS03580	COG0167	dihydroorotate dehydrogenase activity
EGM66_RS03585	COG4211	Belongs to the binding-protein-dependent transport system permease family
EGM66_RS03590	COG1129	ABC transporter
EGM66_RS03595	COG1879	ABC-type sugar transport system periplasmic component
EGM66_RS03600	COG1609	Transcriptional regulator
EGM66_RS03605	COG2311	Membrane
EGM66_RS03620	COG4771	TonB-dependent receptor
EGM66_RS03630	COG0833	amino acid
EGM66_RS03635	COG0583	DNA-binding transcription factor activity
EGM66_RS03640	COG2855	membrane
EGM66_RS03650	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGM66_RS03650	COG1522	sequence-specific DNA binding
EGM66_RS03655	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EGM66_RS03665	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EGM66_RS03670	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EGM66_RS03675	COG2313	pseudouridylate synthase activity
EGM66_RS03680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGM66_RS03685	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EGM66_RS03685	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGM66_RS03685	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGM66_RS03690	COG1105	Belongs to the carbohydrate kinase PfkB family
EGM66_RS03695	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGM66_RS03695	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGM66_RS03700	COG2814	Major facilitator Superfamily
EGM66_RS03715	COG0246	Mannitol dehydrogenase
EGM66_RS03720	COG0523	cobalamin synthesis protein
EGM66_RS03725	COG0671	phosphoesterase, PA-phosphatase related
EGM66_RS03730	COG0791	NLP P60 protein
EGM66_RS03735	COG2200	EAL domain
EGM66_RS03740	COG4166	transmembrane transport
EGM66_RS03745	COG4174	ABC transporter (Permease)
EGM66_RS03750	COG4239	(ABC) transporter, permease
EGM66_RS03755	COG4172	Belongs to the ABC transporter superfamily
EGM66_RS03765	COG2814	Major facilitator Superfamily
EGM66_RS03770	COG1187	pseudouridine synthase activity
EGM66_RS03775	COG1061	Type III restriction enzyme res subunit
EGM66_RS03795	COG3083	sulfuric ester hydrolase activity
EGM66_RS03805	COG3468	outer membrane autotransporter barrel domain protein
EGM66_RS03810	COG2197	response regulator
EGM66_RS03815	COG4235	cytochrome complex assembly
EGM66_RS03815	COG3088	subunit of a heme lyase
EGM66_RS03820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EGM66_RS03825	COG1138	Cytochrome C-type biogenesis protein
EGM66_RS03835	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EGM66_RS03840	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EGM66_RS03845	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EGM66_RS03850	COG4133	protoheme IX ABC transporter activity
EGM66_RS03855	COG3005	denitrification pathway
EGM66_RS03860	COG3043	anaerobic respiration
EGM66_RS03865	COG0348	domain, Protein
EGM66_RS03870	COG0437	4 iron, 4 sulfur cluster binding
EGM66_RS03880	COG3062	negative regulation of establishment of protein localization
EGM66_RS03885	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EGM66_RS03885	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
EGM66_RS03900	COG4615	Cyclic peptide transporter
EGM66_RS03905	COG3145	DNA-N1-methyladenine dioxygenase activity
EGM66_RS03910	COG2169	Transcriptional regulator
EGM66_RS03910	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EGM66_RS03915	COG1477	protein flavinylation
EGM66_RS03920	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EGM66_RS03925	COG2198	Histidine kinase
EGM66_RS03925	COG0642	Histidine kinase
EGM66_RS03930	COG2197	response regulator
EGM66_RS03935	COG0784	Response regulator, receiver
EGM66_RS03935	COG2205	protein histidine kinase activity
EGM66_RS03940	COG3852	Histidine kinase
EGM66_RS03945	COG2204	response regulator
EGM66_RS03950	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EGM66_RS03955	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EGM66_RS03960	COG2031	fatty acid transporter
EGM66_RS03965	COG0183	Belongs to the thiolase family
EGM66_RS03970	COG4676	Protein conserved in bacteria
EGM66_RS03975	COG5445	Predicted secreted protein (DUF2300)
EGM66_RS03980	COG2373	Large extracellular alpha-helical protein
EGM66_RS03985	COG3234	Protein of unknown function (DUF1175)
EGM66_RS03990	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
EGM66_RS03995	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EGM66_RS04005	COG3468	outer membrane autotransporter barrel domain protein
EGM66_RS04010	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EGM66_RS04015	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EGM66_RS04020	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EGM66_RS04025	COG3642	lipopolysaccharide core region biosynthetic process
EGM66_RS04030	COG2814	Major facilitator Superfamily
EGM66_RS04035	COG0583	DNA-binding transcription factor activity
EGM66_RS04040	COG0584	glycerophosphoryl diester phosphodiesterase
EGM66_RS04045	COG2271	Major facilitator Superfamily
EGM66_RS04050	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EGM66_RS04060	COG0247	lactate metabolic process
EGM66_RS04065	COG5464	transposase or invertase
EGM66_RS04075	COG2271	Major facilitator Superfamily
EGM66_RS04085	COG1414	Transcriptional regulator
EGM66_RS04150	COG0318	PFAM AMP-dependent synthetase and ligase
EGM66_RS04160	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EGM66_RS04175	COG1169	isochorismate synthase
EGM66_RS04180	COG4575	ribosome binding
EGM66_RS04185	COG2153	protein acetylation
EGM66_RS04200	COG2234	aminopeptidase activity
EGM66_RS04215	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EGM66_RS04220	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EGM66_RS04230	COG0839	Belongs to the complex I subunit 6 family
EGM66_RS04245	COG1034	ATP synthesis coupled electron transport
EGM66_RS04250	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EGM66_RS04255	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EGM66_RS04275	COG0583	DNA-binding transcription factor activity
EGM66_RS04280	COG0436	Aminotransferase
EGM66_RS04290	COG0471	metal ion transport
EGM66_RS04290	COG0490	domain, Protein
EGM66_RS04295	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EGM66_RS04310	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EGM66_RS04315	COG0280	phosphate acetyltransferase
EGM66_RS04315	COG0857	belongs to the CobB CobQ family
EGM66_RS04320	COG1288	antiporter activity
EGM66_RS04325	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EGM66_RS04330	COG0622	Phosphoesterase
EGM66_RS04335	COG0625	glutathione transferase activity
EGM66_RS04340	COG0625	glutathione transferase activity
EGM66_RS04345	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EGM66_RS04350	COG1090	epimerase
EGM66_RS04355	COG5464	transposase or invertase
EGM66_RS04360	COG4598	ABC transporter
EGM66_RS04365	COG4160	amino acid transport
EGM66_RS04370	COG4215	(ABC) transporter
EGM66_RS04375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGM66_RS04380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGM66_RS04385	COG0163	prenyltransferase activity
EGM66_RS04390	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EGM66_RS04395	COG1286	toxin biosynthetic process
EGM66_RS04400	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
EGM66_RS04405	COG0285	dihydrofolate synthase activity
EGM66_RS04415	COG0586	Pfam SNARE associated Golgi protein
EGM66_RS04425	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EGM66_RS04440	COG2814	Major facilitator Superfamily
EGM66_RS04445	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EGM66_RS04460	COG3101	peptidyl-lysine hydroxylation
EGM66_RS04465	COG0730	response to heat
EGM66_RS04480	COG2890	protein-(glutamine-N5) methyltransferase activity
EGM66_RS04495	COG3539	Fimbrial protein
EGM66_RS04500	COG3539	Fimbrial protein
EGM66_RS04505	COG3539	Fimbrial protein
EGM66_RS04510	COG3121	Chaperone
EGM66_RS04515	COG3188	usher protein
EGM66_RS04520	COG3539	Fimbrial protein
EGM66_RS04525	COG2062	phosphohistidine phosphatase, SixA
EGM66_RS04540	COG3691	Protein conserved in bacteria
EGM66_RS04545	COG2067	long-chain fatty acid transport protein
EGM66_RS04555	COG2853	Lipoprotein
EGM66_RS04560	COG2116	formate transmembrane transporter activity
EGM66_RS04570	COG0582	viral genome integration into host DNA
EGM66_RS04655	COG0477	Major facilitator Superfamily
EGM66_RS04660	COG1566	PFAM secretion protein HlyD family protein
EGM66_RS04665	COG2197	response regulator
EGM66_RS04670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGM66_RS04670	COG2198	Histidine kinase
EGM66_RS04670	COG0784	Response regulator, receiver
EGM66_RS04670	COG2205	protein histidine kinase activity
EGM66_RS04675	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EGM66_RS04680	COG0679	Auxin Efflux Carrier
EGM66_RS04685	COG0028	Belongs to the TPP enzyme family
EGM66_RS04710	COG1560	Kdo2-lipid A biosynthetic process
EGM66_RS04720	COG0436	Aminotransferase
EGM66_RS04725	COG3275	phosphorelay sensor kinase activity
EGM66_RS04730	COG3279	Response regulator of the LytR AlgR family
EGM66_RS04735	COG2207	Transcriptional regulator
EGM66_RS04740	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGM66_RS04740	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGM66_RS04740	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EGM66_RS04745	COG1363	Peptidase, m42
EGM66_RS04750	COG0006	proline dipeptidase activity
EGM66_RS04755	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGM66_RS04760	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGM66_RS04785	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EGM66_RS04790	COG2200	EAL domain
EGM66_RS04790	COG2199	diguanylate cyclase activity
EGM66_RS04805	COG3415	Transposase
EGM66_RS04810	COG3415	Transposase
EGM66_RS04845	COG0583	DNA-binding transcription factor activity
EGM66_RS04855	COG2211	Major facilitator Superfamily
EGM66_RS04860	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EGM66_RS04870	COG0583	DNA-binding transcription factor activity
EGM66_RS04875	COG0385	Bile acid
EGM66_RS04880	COG3530	Putative quorum-sensing-regulated virulence factor
EGM66_RS04900	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EGM66_RS04905	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGM66_RS04910	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EGM66_RS04915	COG2190	(PTS) system
EGM66_RS04930	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EGM66_RS04935	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EGM66_RS04940	COG4208	sulfate ABC transporter
EGM66_RS04945	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EGM66_RS04950	COG4150	thiosulfate binding
EGM66_RS04955	COG1028	Short-chain dehydrogenase reductase Sdr
EGM66_RS04970	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGM66_RS04970	COG1263	PTS System
EGM66_RS04975	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EGM66_RS05000	COG2837	iron assimilation
EGM66_RS05020	COG0860	N-Acetylmuramoyl-L-alanine amidase
EGM66_RS05030	COG2207	Transcriptional regulator
EGM66_RS05035	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
EGM66_RS05040	COG4816	utilization protein
EGM66_RS05050	COG4303	Ethanolamine ammonia lyase large subunit
EGM66_RS05055	COG4819	ethanolamine utilization protein
EGM66_RS05060	COG3192	ethanolamine utilization protein
EGM66_RS05065	COG1454	alcohol dehydrogenase
EGM66_RS05070	COG4820	ethanolamine utilization protein (EutJ)
EGM66_RS05075	COG1012	belongs to the aldehyde dehydrogenase family
EGM66_RS05080	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
EGM66_RS05085	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
EGM66_RS05090	COG0280	phosphate acetyltransferase
EGM66_RS05095	COG4812	Cobalamin adenosyltransferase
EGM66_RS05100	COG4766	ethanolamine catabolic process
EGM66_RS05105	COG4917	ethanolamine utilization protein
EGM66_RS05110	COG4810	utilization protein
EGM66_RS05115	COG0281	malic enzyme
EGM66_RS05115	COG0280	phosphate acetyltransferase
EGM66_RS05120	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EGM66_RS05125	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EGM66_RS05130	COG5342	invasion associated locus B
EGM66_RS05140	COG0493	'glutamate synthase
EGM66_RS05140	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EGM66_RS05145	COG3850	Histidine kinase
EGM66_RS05150	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGM66_RS05160	COG1393	Belongs to the ArsC family
EGM66_RS05175	COG0400	carboxylic ester hydrolase activity
EGM66_RS05185	COG2321	neutral zinc metallopeptidase
EGM66_RS05195	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
EGM66_RS05205	COG2716	regulation of RNA biosynthetic process
EGM66_RS05210	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EGM66_RS05215	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EGM66_RS05220	COG0651	ATP synthesis coupled electron transport
EGM66_RS05225	COG0650	Formate hydrogenlyase subunit 4
EGM66_RS05230	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EGM66_RS05235	COG4237	Hydrogenase 4 membrane
EGM66_RS05240	COG0651	ATP synthesis coupled electron transport
EGM66_RS05245	COG3261	NADH dehydrogenase
EGM66_RS05245	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
EGM66_RS05250	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EGM66_RS05255	COG3260	NADH ubiquinone oxidoreductase 20
EGM66_RS05265	COG3604	Transcriptional regulator
EGM66_RS05270	COG2116	formate transmembrane transporter activity
EGM66_RS05275	COG0628	permease
EGM66_RS05280	COG4783	chaperone-mediated protein folding
EGM66_RS05285	COG1393	Belongs to the ArsC family
EGM66_RS05295	COG2233	PERMEase
EGM66_RS05310	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EGM66_RS05315	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EGM66_RS05320	COG0248	Ppx GppA phosphatase
EGM66_RS05325	COG2200	EAL domain
EGM66_RS05335	COG3133	Outer membrane lipoprotein
EGM66_RS05350	COG3179	chitinase
EGM66_RS05495	COG3728	DNA packaging
EGM66_RS05495	COG5484	DNA packaging
EGM66_RS05560	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EGM66_RS05600	COG0516	GMP reductase activity
EGM66_RS05600	COG0517	IMP dehydrogenase activity
EGM66_RS05625	COG1645	bacterial-type flagellum-dependent swarming motility
EGM66_RS05640	COG2976	Protein conserved in bacteria
EGM66_RS05670	COG4953	penicillin-binding protein 1C
EGM66_RS05675	COG2373	Large extracellular alpha-helical protein
EGM66_RS05680	COG2897	thiosulfate sulfurtransferase activity
EGM66_RS05695	COG2975	iron-sulfur cluster assembly
EGM66_RS05700	COG0633	Ferredoxin
EGM66_RS05720	COG0822	iron-sulfur transferase activity
EGM66_RS05740	COG0483	inositol monophosphate 1-phosphatase activity
EGM66_RS05745	COG1073	alpha beta
EGM66_RS05750	COG3711	transcriptional antiterminator
EGM66_RS05755	COG2814	Major facilitator Superfamily
EGM66_RS05760	COG0583	DNA-binding transcription factor activity
EGM66_RS05765	COG4638	Rieske (2fe-2S)
EGM66_RS05790	COG2259	Doxx family
EGM66_RS05795	COG2017	converts alpha-aldose to the beta-anomer
EGM66_RS05800	COG1063	alcohol dehydrogenase
EGM66_RS05805	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGM66_RS05810	COG1129	ABC transporter
EGM66_RS05815	COG1879	ABC-type sugar transport system periplasmic component
EGM66_RS05820	COG0457	Tetratricopeptide repeat
EGM66_RS05825	COG1940	carbohydrate kinase activity
EGM66_RS05835	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EGM66_RS05835	COG1017	nitric oxide dioxygenase activity
EGM66_RS05840	COG0347	Belongs to the P(II) protein family
EGM66_RS05845	COG2204	response regulator
EGM66_RS05850	COG3170	Tfp pilus assembly protein FimV
EGM66_RS05855	COG2205	protein histidine kinase activity
EGM66_RS05860	COG0047	phosphoribosylformylglycinamidine synthase activity
EGM66_RS05860	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EGM66_RS05875	COG0560	Phosphoserine phosphatase
EGM66_RS05880	COG1737	Transcriptional regulator
EGM66_RS05885	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EGM66_RS05900	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EGM66_RS05920	COG0681	Belongs to the peptidase S26 family
EGM66_RS05930	COG3086	response to oxidative stress
EGM66_RS05935	COG3026	antisigma factor binding
EGM66_RS05940	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
EGM66_RS05945	COG1595	DNA-templated transcription, initiation
EGM66_RS05955	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EGM66_RS05965	COG0513	Belongs to the DEAD box helicase family
EGM66_RS05970	COG0583	DNA-binding transcription factor activity
EGM66_RS05990	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EGM66_RS05995	COG3118	belongs to the thioredoxin family
EGM66_RS06000	COG3148	PFAM DTW domain containing protein
EGM66_RS06005	COG0045	succinate-CoA ligase (ADP-forming) activity
EGM66_RS06005	COG1042	CoA-binding domain protein
EGM66_RS06005	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EGM66_RS06010	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EGM66_RS06015	COG5544	Lipoprotein
EGM66_RS06020	COG0477	Major facilitator Superfamily
EGM66_RS06050	COG0542	response to heat
EGM66_RS06060	COG0564	pseudouridine synthase activity
EGM66_RS06065	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EGM66_RS06070	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EGM66_RS06080	COG1605	Chorismate mutase
EGM66_RS06080	COG0077	Prephenate dehydratase
EGM66_RS06085	COG0287	Prephenate dehydrogenase
EGM66_RS06085	COG1605	Chorismate mutase
EGM66_RS06090	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EGM66_RS06105	COG2199	diguanylate cyclase activity
EGM66_RS06110	COG2885	chlorophyll binding
EGM66_RS06145	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EGM66_RS06150	COG4137	Cytochrome C assembly protein
EGM66_RS06155	COG4536	flavin adenine dinucleotide binding
EGM66_RS06175	COG0497	DNA recombination
EGM66_RS06180	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EGM66_RS06190	COG2867	negative regulation of translational initiation
EGM66_RS06205	COG3468	outer membrane autotransporter barrel domain protein
EGM66_RS06230	COG0366	Alpha amylase catalytic
EGM66_RS06240	COG0579	oxidoreductase
EGM66_RS06245	COG1012	belongs to the aldehyde dehydrogenase family
EGM66_RS06250	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EGM66_RS06260	COG1802	Transcriptional regulator
EGM66_RS06265	COG1652	LysM domain
EGM66_RS06270	COG0401	homolog of Blt101
EGM66_RS06295	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EGM66_RS06300	COG2916	Histone family protein nucleoid-structuring protein H-NS
EGM66_RS06315	COG4575	ribosome binding
EGM66_RS06320	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EGM66_RS06330	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EGM66_RS06335	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EGM66_RS06345	COG4175	Glycine betaine
EGM66_RS06350	COG4176	ABC-type proline glycine betaine transport system permease component
EGM66_RS06355	COG2113	Glycine betaine
EGM66_RS06360	COG2814	Major facilitator Superfamily
EGM66_RS06365	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EGM66_RS06375	COG1846	Transcriptional regulator
EGM66_RS06380	COG1566	PFAM secretion protein HlyD family protein
EGM66_RS06385	COG2814	Major facilitator Superfamily
EGM66_RS06400	COG1238	metal cluster binding
EGM66_RS06405	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EGM66_RS06440	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EGM66_RS06460	COG1546	Belongs to the CinA family
EGM66_RS06465	COG2951	lytic endotransglycosylase activity
EGM66_RS06470	COG3730	PTS system glucitol sorbitol-specific
EGM66_RS06475	COG3732	PTS system glucitol sorbitol-specific
EGM66_RS06485	COG1028	Short-chain dehydrogenase reductase Sdr
EGM66_RS06490	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGM66_RS06495	COG1349	DNA-binding transcription factor activity
EGM66_RS06520	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
EGM66_RS06525	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EGM66_RS06530	COG1609	Transcriptional regulator
EGM66_RS06535	COG1263	PTS System
EGM66_RS06535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGM66_RS06540	COG2723	6-phospho-beta-galactosidase activity
EGM66_RS06545	COG5499	transcription regulator containing HTH domain
EGM66_RS06550	COG4680	protein conserved in bacteria
EGM66_RS06555	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EGM66_RS06565	COG3260	NADH ubiquinone oxidoreductase 20
EGM66_RS06570	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EGM66_RS06575	COG3261	NADH dehydrogenase
EGM66_RS06575	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
EGM66_RS06580	COG0650	Formate hydrogenlyase subunit 4
EGM66_RS06585	COG0651	ATP synthesis coupled electron transport
EGM66_RS06590	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EGM66_RS06605	COG0375	protein maturation
EGM66_RS06610	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EGM66_RS06615	COG0298	carbon dioxide binding
EGM66_RS06620	COG0409	Hydrogenase expression formation protein
EGM66_RS06625	COG0309	Hydrogenase expression formation protein (HypE)
EGM66_RS06650	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EGM66_RS06655	COG1349	DNA-binding transcription factor activity
EGM66_RS06660	COG2084	Dehydrogenase
EGM66_RS06665	COG3395	kinase activity
EGM66_RS06670	COG0235	Class ii aldolase
EGM66_RS06675	COG3622	Belongs to the hyi family
EGM66_RS06680	COG2610	gluconate transmembrane transporter activity
EGM66_RS06690	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EGM66_RS06695	COG0163	prenyltransferase activity
EGM66_RS06705	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EGM66_RS06710	COG4942	peptidase
EGM66_RS06710	COG1388	LysM domain
EGM66_RS06765	COG2234	aminopeptidase activity
EGM66_RS06770	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EGM66_RS06775	COG1518	maintenance of DNA repeat elements
EGM66_RS06790	COG1857	crispr-associated protein
EGM66_RS06805	COG1203	CRISPR-associated helicase, Cas3
EGM66_RS06835	COG0720	synthase
EGM66_RS06840	COG0644	oxidoreductase
EGM66_RS06845	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
EGM66_RS06850	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EGM66_RS06860	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EGM66_RS06865	COG2086	electron transfer activity
EGM66_RS06870	COG0477	Major facilitator Superfamily
EGM66_RS06875	COG0277	FAD linked oxidase domain protein
EGM66_RS06880	COG1028	Short-chain dehydrogenase reductase Sdr
EGM66_RS06885	COG2223	nitrite transmembrane transporter activity
EGM66_RS06890	COG1070	Carbohydrate kinase
EGM66_RS06895	COG0602	queuosine metabolic process
EGM66_RS06905	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
EGM66_RS06930	COG3956	TIGRFAM MazG family protein
EGM66_RS06935	COG2337	Toxic component of a toxin-antitoxin (TA) module
EGM66_RS06940	COG2336	PFAM SpoVT AbrB
EGM66_RS06945	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EGM66_RS06955	COG2205	protein histidine kinase activity
EGM66_RS06955	COG4999	Histidine kinase
EGM66_RS06955	COG3850	Histidine kinase
EGM66_RS06955	COG3437	response regulator, receiver
EGM66_RS06960	COG4948	Mandelate Racemase Muconate Lactonizing
EGM66_RS06965	COG4948	Mandelate Racemase Muconate Lactonizing
EGM66_RS06970	COG2271	Major facilitator Superfamily
EGM66_RS06975	COG0716	FMN binding
EGM66_RS06980	COG0564	pseudouridine synthase activity
EGM66_RS06985	COG3098	single-species biofilm formation
EGM66_RS07000	COG1611	Belongs to the LOG family
EGM66_RS07005	COG0814	amino acid
EGM66_RS07010	COG1760	l-serine dehydratase
EGM66_RS07020	COG1454	alcohol dehydrogenase
EGM66_RS07025	COG0235	Class ii aldolase
EGM66_RS07035	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EGM66_RS07040	COG1609	Transcriptional regulator
EGM66_RS07045	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGM66_RS07050	COG1129	ABC transporter
EGM66_RS07060	COG1070	Carbohydrate kinase
EGM66_RS07070	COG1349	DNA-binding transcription factor activity
EGM66_RS07080	COG2363	Small membrane protein
EGM66_RS07085	COG0583	DNA-binding transcription factor activity
EGM66_RS07095	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EGM66_RS07100	COG2166	iron-sulfur cluster assembly
EGM66_RS07105	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EGM66_RS07110	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
EGM66_RS07140	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EGM66_RS07145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGM66_RS07145	COG1263	PTS System
EGM66_RS07150	COG3711	transcriptional antiterminator
EGM66_RS07155	COG0860	N-Acetylmuramoyl-L-alanine amidase
EGM66_RS07160	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EGM66_RS07160	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EGM66_RS07165	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EGM66_RS07170	COG1074	ATP-dependent DNA helicase activity
EGM66_RS07180	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EGM66_RS07185	COG4967	type IV pilus modification protein PilV
EGM66_RS07195	COG4795	General secretion pathway protein
EGM66_RS07200	COG2165	general secretion pathway protein
EGM66_RS07215	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
EGM66_RS07235	COG0861	Integral membrane protein TerC family
EGM66_RS07245	COG0667	Aldo Keto reductase
EGM66_RS07260	COG1609	Transcriptional regulator
EGM66_RS07270	COG0583	DNA-binding transcription factor activity
EGM66_RS07275	COG1794	racemase activity, acting on amino acids and derivatives
EGM66_RS07280	COG2814	Major facilitator Superfamily
EGM66_RS07285	COG1028	Short-chain dehydrogenase reductase Sdr
EGM66_RS07295	COG0183	Belongs to the thiolase family
EGM66_RS07300	COG0814	amino acid
EGM66_RS07305	COG2771	luxR family
EGM66_RS07310	COG3710	Transcriptional regulator
EGM66_RS07340	COG0457	Tetratricopeptide repeat
EGM66_RS07345	COG0457	Tetratricopeptide repeat
EGM66_RS07345	COG3710	Transcriptional regulator
EGM66_RS07355	COG0741	lytic transglycosylase activity
EGM66_RS07360	COG2197	response regulator
EGM66_RS07465	COG2207	Transcriptional regulator
EGM66_RS07485	COG4942	peptidase
EGM66_RS07490	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EGM66_RS07495	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EGM66_RS07500	COG2080	2 iron, 2 sulfur cluster binding
EGM66_RS07505	COG3829	transcription factor binding
EGM66_RS07510	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EGM66_RS07515	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EGM66_RS07520	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EGM66_RS07530	COG0549	Belongs to the carbamate kinase family
EGM66_RS07535	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EGM66_RS07535	COG3608	succinylglutamate desuccinylase aspartoacylase
EGM66_RS07540	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EGM66_RS07545	COG2068	MobA-Related Protein
EGM66_RS07550	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EGM66_RS07550	COG0493	'glutamate synthase
EGM66_RS07555	COG0402	S-adenosylhomocysteine deaminase activity
EGM66_RS07560	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EGM66_RS07565	COG2080	2 iron, 2 sulfur cluster binding
EGM66_RS07565	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EGM66_RS07575	COG0402	S-adenosylhomocysteine deaminase activity
EGM66_RS07580	COG2252	PERMEase
EGM66_RS07585	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EGM66_RS07590	COG0493	'glutamate synthase
EGM66_RS07590	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EGM66_RS07595	COG2233	PERMEase
EGM66_RS07610	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EGM66_RS07620	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EGM66_RS07625	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EGM66_RS07630	COG4974	Belongs to the 'phage' integrase family
EGM66_RS07635	COG0716	FMN binding
EGM66_RS07645	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EGM66_RS07655	COG1272	protein, Hemolysin III
EGM66_RS07665	COG2723	6-phospho-beta-galactosidase activity
EGM66_RS07690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGM66_RS07695	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGM66_RS07700	COG0006	proline dipeptidase activity
EGM66_RS07720	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EGM66_RS07730	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EGM66_RS07745	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EGM66_RS07745	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EGM66_RS07750	COG1703	isobutyryl-CoA mutase activity
EGM66_RS07755	COG1024	Enoyl-CoA hydratase
EGM66_RS07760	COG0427	acetyl-CoA hydrolase
EGM66_RS07765	COG0583	DNA-binding transcription factor activity
EGM66_RS07770	COG2968	Membrane
EGM66_RS07775	COG1279	arginine transmembrane transporter activity
EGM66_RS07780	COG0668	transmembrane transport
EGM66_RS07785	COG0191	fructose-bisphosphate aldolase activity
EGM66_RS07800	COG1072	(Pantothenic acid kinase))
EGM66_RS07805	COG3722	fumarate hydratase activity
EGM66_RS07810	COG1494	fructose-1,6-bisphosphatase
EGM66_RS07815	COG1063	alcohol dehydrogenase
EGM66_RS07820	COG2213	PTS system mannitol-specific
EGM66_RS07825	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGM66_RS07830	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EGM66_RS07835	COG0501	Belongs to the peptidase M48B family
EGM66_RS07845	COG1166	arginine decarboxylase activity
EGM66_RS07870	COG2814	Major facilitator Superfamily
EGM66_RS07880	COG2356	endonuclease I
EGM66_RS07885	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EGM66_RS07890	COG0189	ligase activity
EGM66_RS07905	COG2805	Type II/IV secretion system protein
EGM66_RS07910	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EGM66_RS07915	COG0762	integral membrane protein
EGM66_RS07930	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EGM66_RS07940	COG0252	asparaginase activity
EGM66_RS07950	COG3171	Protein conserved in bacteria
EGM66_RS07960	COG1194	a g-specific adenine glycosylase
EGM66_RS07975	COG2211	Major facilitator Superfamily
EGM66_RS07980	COG1982	Orn Lys Arg decarboxylase major
EGM66_RS07985	COG1811	Na channel or pump
EGM66_RS07995	COG0582	viral genome integration into host DNA
EGM66_RS08015	COG3436	PFAM IS66 Orf2 family protein
EGM66_RS08125	COG3436	PFAM IS66 Orf2 family protein
EGM66_RS08130	COG4372	Transposase
EGM66_RS08135	COG3468	outer membrane autotransporter barrel domain protein
EGM66_RS08160	COG2003	Belongs to the UPF0758 family
EGM66_RS08215	COG1091	dTDP-4-dehydrorhamnose reductase activity
EGM66_RS08230	COG3039	Transposase
EGM66_RS08240	COG1216	Glycosyl transferase, family 2
EGM66_RS08240	COG0438	transferase activity, transferring glycosyl groups
EGM66_RS08265	COG1216	Glycosyl transferase, family 2
EGM66_RS08265	COG0438	transferase activity, transferring glycosyl groups
EGM66_RS08270	COG1216	Glycosyl transferase, family 2
EGM66_RS08270	COG0438	transferase activity, transferring glycosyl groups
EGM66_RS08300	COG3039	Transposase
EGM66_RS08310	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
EGM66_RS08340	COG2165	general secretion pathway protein
EGM66_RS08345	COG1459	type II secretion system
EGM66_RS08350	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EGM66_RS08380	COG3064	Membrane
EGM66_RS08385	COG1620	l-lactate permease
EGM66_RS08390	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EGM66_RS08395	COG3193	protein, possibly involved in utilization of glycolate and propanediol
EGM66_RS08400	COG0247	lactate metabolic process
EGM66_RS08405	COG0277	FAD linked oxidase domain protein
EGM66_RS08410	COG0277	FAD linked oxidase domain protein
EGM66_RS08415	COG2186	Transcriptional regulator
EGM66_RS08420	COG0456	acetyltransferase
EGM66_RS08425	COG0318	PFAM AMP-dependent synthetase and ligase
EGM66_RS08435	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EGM66_RS08440	COG0156	8-amino-7-oxononanoate synthase activity
EGM66_RS08450	COG0795	lipopolysaccharide-transporting ATPase activity
EGM66_RS08455	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
EGM66_RS08465	COG2244	polysaccharide biosynthetic process
EGM66_RS08470	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EGM66_RS08475	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EGM66_RS08480	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EGM66_RS08485	COG0306	phosphate transporter
EGM66_RS08490	COG0754	glutathionylspermidine amidase activity
EGM66_RS08495	COG0625	glutathione transferase activity
EGM66_RS08500	COG0298	carbon dioxide binding
EGM66_RS08510	COG1773	rubredoxin
EGM66_RS08515	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EGM66_RS08520	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
EGM66_RS08525	COG5557	Pfam Polysulphide reductase, NrfD
EGM66_RS08530	COG0437	4 iron, 4 sulfur cluster binding
EGM66_RS08535	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
EGM66_RS08550	COG0667	Aldo Keto reductase
EGM66_RS08560	COG1028	Short-chain dehydrogenase reductase Sdr
EGM66_RS08565	COG0848	biopolymer transport protein
EGM66_RS08570	COG0811	peptide transport
EGM66_RS08575	COG0626	cystathionine gamma-synthase activity
EGM66_RS08580	COG0586	Pfam SNARE associated Golgi protein
EGM66_RS08585	COG2207	Transcriptional regulator
EGM66_RS08590	COG1979	alcohol dehydrogenase
EGM66_RS08595	COG0656	L-ascorbic acid biosynthetic process
EGM66_RS08605	COG4238	major outer membrane lipoprotein
EGM66_RS08615	COG2132	Multicopper oxidase
EGM66_RS08620	COG0204	Acyl-transferase
EGM66_RS08625	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EGM66_RS08630	COG4166	transmembrane transport
EGM66_RS08635	COG2944	sequence-specific DNA binding
EGM66_RS08645	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
EGM66_RS08650	COG3111	PFAM Bacterial OB fold (BOF) protein
EGM66_RS08655	COG0745	RESPONSE REGULATOR receiver
EGM66_RS08660	COG0642	Histidine kinase
EGM66_RS08670	COG2249	NAD(P)H dehydrogenase (quinone) activity
EGM66_RS08675	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EGM66_RS08680	COG0187	DNA topoisomerase II activity
EGM66_RS08685	COG3150	esterase
EGM66_RS08690	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EGM66_RS08695	COG3151	Protein conserved in bacteria
EGM66_RS08700	COG0494	nUDIX hydrolase
EGM66_RS08705	COG1538	Outer membrane efflux protein
EGM66_RS08715	COG0754	glutathionylspermidine amidase activity
EGM66_RS08720	COG3384	dioxygenase
EGM66_RS08735	COG2960	long-chain fatty acid transporting porin activity
EGM66_RS08740	COG3539	Fimbrial protein
EGM66_RS08745	COG3188	usher protein
EGM66_RS08750	COG3121	Chaperone
EGM66_RS08755	COG3539	Fimbrial protein
EGM66_RS08765	COG1585	Membrane protein implicated in regulation of membrane protease activity
EGM66_RS08770	COG2268	Band 7 protein
EGM66_RS08795	COG3025	triphosphatase activity
EGM66_RS08800	COG4991	sh3 domain protein
EGM66_RS08815	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EGM66_RS08830	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EGM66_RS08835	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EGM66_RS08850	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EGM66_RS08855	COG0358	DNA primase activity
EGM66_RS08860	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EGM66_RS08875	COG2375	cellular response to nickel ion
EGM66_RS08885	COG1695	Transcriptional regulator
EGM66_RS08890	COG0840	transmembrane signaling receptor activity
EGM66_RS08900	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EGM66_RS08905	COG1609	Transcriptional regulator
EGM66_RS08910	COG3250	beta-galactosidase activity
EGM66_RS08915	COG2731	YhcH YjgK YiaL family protein
EGM66_RS08930	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
EGM66_RS08930	COG3408	Glycogen debranching enzyme
EGM66_RS08935	COG0446	pyridine nucleotide-disulphide oxidoreductase
EGM66_RS08935	COG1902	pentaerythritol trinitrate reductase activity
EGM66_RS08945	COG1451	nucleotide metabolic process
EGM66_RS08950	COG2949	membrane
EGM66_RS08955	COG0673	inositol 2-dehydrogenase activity
EGM66_RS08960	COG0861	Integral membrane protein TerC family
EGM66_RS08965	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
EGM66_RS08975	COG2721	sulfolactate sulfo-lyase activity
EGM66_RS08985	COG2271	Major facilitator Superfamily
EGM66_RS08990	COG2186	Transcriptional regulator
EGM66_RS08995	COG0586	Pfam SNARE associated Golgi protein
EGM66_RS09005	COG1422	Protein of unknown function (DUF1090)
EGM66_RS09010	COG4575	ribosome binding
EGM66_RS09015	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
EGM66_RS09025	COG2259	Doxx family
EGM66_RS09030	COG0435	Glutathione S-transferase
EGM66_RS09035	COG3152	Membrane
EGM66_RS09040	COG3152	Membrane
EGM66_RS09045	COG0583	DNA-binding transcription factor activity
EGM66_RS09050	COG1741	Belongs to the pirin family
EGM66_RS09065	COG0814	amino acid
EGM66_RS09070	COG1760	l-serine dehydratase
EGM66_RS09075	COG0251	oxidation-reduction process
EGM66_RS09080	COG1882	Formate acetyltransferase
EGM66_RS09085	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EGM66_RS09095	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EGM66_RS09100	COG0583	DNA-binding transcription factor activity
EGM66_RS09125	COG1929	Belongs to the glycerate kinase type-1 family
EGM66_RS09130	COG2084	Dehydrogenase
EGM66_RS09140	COG2271	Major facilitator Superfamily
EGM66_RS09145	COG2721	sulfolactate sulfo-lyase activity
EGM66_RS09150	COG2002	toxin-antitoxin pair type II binding
EGM66_RS09160	COG1349	DNA-binding transcription factor activity
EGM66_RS09170	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGM66_RS09180	COG3716	PTS system mannose fructose sorbose family IID component
EGM66_RS09185	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGM66_RS09190	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EGM66_RS09195	COG2222	sugar isomerase
EGM66_RS09205	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGM66_RS09210	COG3715	PTS system
EGM66_RS09215	COG3716	PTS system mannose fructose sorbose family IID component
EGM66_RS09220	COG0363	glucosamine-6-phosphate deaminase activity
EGM66_RS09225	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EGM66_RS09245	COG2823	Periplasmic or secreted lipoprotein
EGM66_RS09250	COG0701	Predicted permease
EGM66_RS09255	COG0702	epimerase
EGM66_RS09260	COG0693	protein deglycase activity
EGM66_RS09275	COG3153	acetyltransferase
EGM66_RS09280	COG3154	lipid carrier protein
EGM66_RS09285	COG0826	peptidase U32
EGM66_RS09290	COG0826	peptidase U32
EGM66_RS09295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGM66_RS09300	COG0814	amino acid
EGM66_RS09305	COG0513	Belongs to the DEAD box helicase family
EGM66_RS09345	COG0195	Participates in both transcription termination and antitermination
EGM66_RS09365	COG2194	sulfuric ester hydrolase activity
EGM66_RS09375	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EGM66_RS09385	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EGM66_RS09390	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EGM66_RS09400	COG1534	Rna-binding protein
EGM66_RS09405	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EGM66_RS09410	COG2027	D-alanyl-D-alanine carboxypeptidase
EGM66_RS09420	COG0697	spore germination
EGM66_RS09435	COG0142	geranyltranstransferase activity
EGM66_RS09440	COG3423	Transcriptional regulator
EGM66_RS09450	COG5007	Belongs to the BolA IbaG family
EGM66_RS09455	COG3113	response to antibiotic
EGM66_RS09460	COG2854	intermembrane phospholipid transfer
EGM66_RS09465	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EGM66_RS09470	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EGM66_RS09475	COG1127	ABC transporter
EGM66_RS09480	COG0530	calcium, potassium:sodium antiporter activity
EGM66_RS09485	COG0517	IMP dehydrogenase activity
EGM66_RS09485	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EGM66_RS09490	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EGM66_RS09495	COG3117	lipopolysaccharide transmembrane transporter activity
EGM66_RS09500	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EGM66_RS09505	COG1137	ATPase activity
EGM66_RS09510	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EGM66_RS09515	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EGM66_RS09530	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGM66_RS09535	COG0515	serine threonine protein kinase
EGM66_RS09545	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
EGM66_RS09550	COG5002	protein histidine kinase activity
EGM66_RS09550	COG2198	Histidine kinase
EGM66_RS09550	COG0784	Response regulator, receiver
EGM66_RS09555	COG1242	4 iron, 4 sulfur cluster binding
EGM66_RS09560	COG0069	glutamate synthase activity
EGM66_RS09560	COG0070	glutamate synthase
EGM66_RS09560	COG0067	glutamate synthase
EGM66_RS09565	COG0493	'glutamate synthase
EGM66_RS09570	COG4804	nuclease activity
EGM66_RS09575	COG2731	YhcH YjgK YiaL family protein
EGM66_RS09605	COG3069	C4-dicarboxylate transmembrane transporter activity
EGM66_RS09610	COG2969	positive regulation of protein catabolic process
EGM66_RS09615	COG0625	glutathione transferase activity
EGM66_RS09635	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EGM66_RS09640	COG3105	Protein conserved in bacteria
EGM66_RS09645	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EGM66_RS09650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EGM66_RS09670	COG2732	(Barnase) inhibitor
EGM66_RS09690	COG0583	DNA-binding transcription factor activity
EGM66_RS09695	COG0312	modulator of DNA gyrase
EGM66_RS09700	COG3164	Protein of unknown function
EGM66_RS09705	COG1530	ribonuclease E activity
EGM66_RS09715	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EGM66_RS09720	COG1792	Involved in formation and maintenance of cell shape
EGM66_RS09725	COG1077	Cell shape determining protein MreB Mrl
EGM66_RS09735	COG2199	diguanylate cyclase activity
EGM66_RS09735	COG2200	EAL domain
EGM66_RS09740	COG0604	alcohol dehydrogenase
EGM66_RS09745	COG0511	ligase activity, forming carbon-carbon bonds
EGM66_RS09750	COG0439	Biotin carboxylase
EGM66_RS09755	COG3924	membrane
EGM66_RS09760	COG4145	pantothenate transmembrane transporter activity
EGM66_RS09770	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EGM66_RS09780	COG2189	Belongs to the N(4) N(6)-methyltransferase family
EGM66_RS09790	COG1309	transcriptional regulator
EGM66_RS09795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGM66_RS09800	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGM66_RS09810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGM66_RS09815	COG4597	amino acid ABC transporter
EGM66_RS09820	COG0765	amino acid transport
EGM66_RS09825	COG1126	abc transporter atp-binding protein
EGM66_RS09865	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EGM66_RS09885	COG0551	DNA topoisomerase type I activity
EGM66_RS09895	COG0758	DNA mediated transformation
EGM66_RS09915	COG0569	domain protein
EGM66_RS09925	COG3036	rescue of stalled ribosome
EGM66_RS09930	COG0789	Transcriptional regulator
EGM66_RS09970	COG0201	protein transport
EGM66_RS10060	COG0089	rRNA binding
EGM66_RS10130	COG2964	Protein conserved in bacteria
EGM66_RS10135	COG0545	Peptidyl-prolyl cis-trans isomerase
EGM66_RS10145	COG1047	Peptidyl-prolyl cis-trans
EGM66_RS10150	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
EGM66_RS10165	COG0488	(ABC) transporter
EGM66_RS10170	COG0429	hydrolase of the alpha beta-hydrolase fold
EGM66_RS10180	COG3954	Phosphoribulokinase
EGM66_RS10185	COG1765	OsmC-like protein
EGM66_RS10190	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EGM66_RS10195	COG1289	transmembrane transporter activity
EGM66_RS10200	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EGM66_RS10205	COG0512	Glutamine amidotransferase of anthranilate synthase
EGM66_RS10210	COG2184	nucleotidyltransferase activity
EGM66_RS10220	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EGM66_RS10235	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EGM66_RS10240	COG2146	nitrite reductase [NAD(P)H] activity
EGM66_RS10245	COG2116	formate transmembrane transporter activity
EGM66_RS10260	COG0626	cystathionine gamma-synthase activity
EGM66_RS10275	COG1735	metal-dependent hydrolase with the TIM-barrel fold
EGM66_RS10280	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EGM66_RS10285	COG3457	Alanine racemase
EGM66_RS10295	COG2188	Transcriptional regulator
EGM66_RS10300	COG0180	Tryptophanyl-tRNA synthetase
EGM66_RS10305	COG0546	phosphoglycolate phosphatase activity
EGM66_RS10310	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EGM66_RS10315	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EGM66_RS10320	COG3266	domain, Protein
EGM66_RS10335	COG4796	Type ii and iii secretion system protein
EGM66_RS10350	COG3166	PFAM Fimbrial assembly family protein
EGM66_RS10355	COG4972	Pilus assembly protein
EGM66_RS10360	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EGM66_RS10365	COG0494	nUDIX hydrolase
EGM66_RS10375	COG1011	Hydrolase
EGM66_RS10380	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EGM66_RS10390	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
EGM66_RS10420	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EGM66_RS10425	COG2183	response to ionizing radiation
EGM66_RS10430	COG1918	ferrous iron import across plasma membrane
EGM66_RS10435	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EGM66_RS10445	COG5464	transposase or invertase
EGM66_RS10455	COG1040	competence protein
EGM66_RS10465	COG2610	gluconate transmembrane transporter activity
EGM66_RS10470	COG1640	4-alpha-glucanotransferase
EGM66_RS10475	COG0058	SHG alpha-glucan phosphorylase activity
EGM66_RS10490	COG1690	Belongs to the RtcB family
EGM66_RS10495	COG4650	regulator
EGM66_RS10500	COG1349	DNA-binding transcription factor activity
EGM66_RS10515	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EGM66_RS10540	COG0058	SHG alpha-glucan phosphorylase activity
EGM66_RS10560	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EGM66_RS10565	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EGM66_RS10570	COG2095	MarC family integral membrane protein
EGM66_RS10575	COG2610	gluconate transmembrane transporter activity
EGM66_RS10580	COG3265	gluconokinase activity
EGM66_RS10585	COG1609	Transcriptional regulator
EGM66_RS10590	COG1741	Belongs to the pirin family
EGM66_RS10595	COG0673	inositol 2-dehydrogenase activity
EGM66_RS10600	COG1247	-acetyltransferase
EGM66_RS10605	COG3157	Type VI secretion system effector, Hcp
EGM66_RS10625	COG0405	Gamma-glutamyltransferase
EGM66_RS10635	COG0584	glycerophosphoryl diester phosphodiesterase
EGM66_RS10650	COG1175	transmembrane transport
EGM66_RS10655	COG1653	transport
EGM66_RS10660	COG0410	ABC transporter
EGM66_RS10665	COG0411	ABC transporter
EGM66_RS10670	COG4177	L-phenylalanine transmembrane transporter activity
EGM66_RS10675	COG0559	Belongs to the binding-protein-dependent transport system permease family
EGM66_RS10680	COG0683	leucine binding
EGM66_RS10685	COG0456	acetyltransferase
EGM66_RS10690	COG0683	leucine binding
EGM66_RS10695	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EGM66_RS10700	COG2177	Part of the ABC transporter FtsEX involved in
EGM66_RS10705	COG2884	Cell division ATP-binding protein ftsE
EGM66_RS10710	COG0552	protein localization to endoplasmic reticulum
EGM66_RS10715	COG0742	ribosomal rna small subunit methyltransferase
EGM66_RS10720	COG3776	membrane
EGM66_RS10730	COG3714	YhhN family
EGM66_RS10745	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EGM66_RS10760	COG0628	permease
EGM66_RS10765	COG2091	lysine biosynthetic process via aminoadipic acid
EGM66_RS10770	COG0747	negative chemotaxis
EGM66_RS10775	COG0601	transmembrane transport
EGM66_RS10780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EGM66_RS10800	COG3209	COG3209 Rhs family protein
EGM66_RS10825	COG3209	COG3209 Rhs family protein
EGM66_RS10835	COG1413	lyase activity
EGM66_RS10840	COG3209	COG3209 Rhs family protein
EGM66_RS10860	COG0842	Transport permease protein
EGM66_RS10865	COG0842	Transport permease protein
EGM66_RS10865	COG1129	ABC transporter
EGM66_RS10870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGM66_RS10890	COG2081	HI0933 family
EGM66_RS10895	COG0306	phosphate transporter
EGM66_RS10905	COG0589	response to stress
EGM66_RS10910	COG3104	oligopeptide transport
EGM66_RS10920	COG0339	signal peptide processing
EGM66_RS10925	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EGM66_RS10930	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGM66_RS10940	COG0640	Transcriptional regulator
EGM66_RS10945	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EGM66_RS10950	COG1393	Belongs to the ArsC family
EGM66_RS10970	COG3065	identical protein binding
EGM66_RS10975	COG2197	response regulator
EGM66_RS10980	COG3720	iron ion transport
EGM66_RS10985	COG4771	TonB-dependent receptor
EGM66_RS10995	COG4558	Periplasmic binding protein
EGM66_RS11005	COG3721	Heme iron utilization protein
EGM66_RS11015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGM66_RS11025	COG1285	pathogenesis
EGM66_RS11040	COG3247	response to pH
EGM66_RS11045	COG2771	luxR family
EGM66_RS11055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGM66_RS11060	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGM66_RS11065	COG2207	Transcriptional regulator
EGM66_RS11075	COG0076	glutamate decarboxylase activity
EGM66_RS11080	COG1858	cytochrome C peroxidase
EGM66_RS11090	COG2197	response regulator
EGM66_RS11095	COG0583	DNA-binding transcription factor activity
EGM66_RS11100	COG1295	ribonuclease BN
EGM66_RS11105	COG0477	Major facilitator Superfamily
EGM66_RS11110	COG2982	Protein involved in outer membrane biogenesis
EGM66_RS11115	COG2200	EAL domain
EGM66_RS11125	COG0612	Peptidase, M16
EGM66_RS11135	COG2200	EAL domain
EGM66_RS11135	COG2199	diguanylate cyclase activity
EGM66_RS11140	COG0457	Tetratricopeptide repeat
EGM66_RS11140	COG3118	belongs to the thioredoxin family
EGM66_RS11145	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EGM66_RS11150	COG1215	transferase activity, transferring glycosyl groups
EGM66_RS11155	COG1215	transferase activity, transferring glycosyl groups
EGM66_RS11180	COG2194	sulfuric ester hydrolase activity
EGM66_RS11210	COG0814	amino acid
EGM66_RS11215	COG4608	Belongs to the ABC transporter superfamily
EGM66_RS11220	COG0444	Belongs to the ABC transporter superfamily
EGM66_RS11225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EGM66_RS11230	COG0601	transmembrane transport
EGM66_RS11240	COG0747	negative chemotaxis
EGM66_RS11255	COG2194	sulfuric ester hydrolase activity
EGM66_RS11260	COG2223	nitrite transmembrane transporter activity
EGM66_RS11265	COG5571	outer membrane autotransporter
EGM66_RS11270	COG2818	Glycosylase
EGM66_RS11275	COG0456	acetyltransferase
EGM66_RS11280	COG0243	molybdopterin cofactor binding
EGM66_RS11285	COG2885	chlorophyll binding
EGM66_RS11300	COG2944	sequence-specific DNA binding
EGM66_RS11305	COG1278	Cold shock
EGM66_RS11340	COG3274	enterobacterial common antigen metabolic process
EGM66_RS11345	COG4682	membrane
EGM66_RS11350	COG4682	membrane
EGM66_RS11355	COG1070	Carbohydrate kinase
EGM66_RS11365	COG4213	ABC transporter substrate-binding protein
EGM66_RS11375	COG4214	carbohydrate transport
EGM66_RS11380	COG1609	Transcriptional regulator
EGM66_RS11380	COG2207	Transcriptional regulator
EGM66_RS11385	COG2992	FlgJ-related protein
EGM66_RS11390	COG0366	Alpha amylase catalytic
EGM66_RS11395	COG3977	Valine--pyruvate aminotransferase
EGM66_RS11400	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EGM66_RS11405	COG1414	Transcriptional regulator
EGM66_RS11415	COG2731	YhcH YjgK YiaL family protein
EGM66_RS11420	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EGM66_RS11425	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EGM66_RS11430	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EGM66_RS11435	COG1070	Carbohydrate kinase
EGM66_RS11440	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
EGM66_RS11445	COG3623	hexulose-6-phosphate isomerase
EGM66_RS11450	COG0235	Class ii aldolase
EGM66_RS11460	COG2211	Major facilitator Superfamily
EGM66_RS11470	COG3713	MltA-interacting MipA family protein
EGM66_RS11475	COG0583	DNA-binding transcription factor activity
EGM66_RS11480	COG1566	PFAM secretion protein HlyD family protein
EGM66_RS11495	COG1012	belongs to the aldehyde dehydrogenase family
EGM66_RS11510	COG1454	alcohol dehydrogenase
EGM66_RS11515	COG3276	selenocysteine insertion sequence binding
EGM66_RS11525	COG0625	glutathione transferase activity
EGM66_RS11530	COG1566	PFAM secretion protein HlyD family protein
EGM66_RS11540	COG2213	PTS system mannitol-specific
EGM66_RS11540	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGM66_RS11550	COG3722	fumarate hydratase activity
EGM66_RS11570	COG5295	Hep Hag repeat protein
EGM66_RS11575	COG1620	l-lactate permease
EGM66_RS11580	COG2186	Transcriptional regulator
EGM66_RS11590	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EGM66_RS11595	COG1045	serine acetyltransferase
EGM66_RS11610	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EGM66_RS11615	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EGM66_RS11630	COG4942	peptidase
EGM66_RS11635	COG2861	carbohydrate metabolic process
EGM66_RS11640	COG1216	Glycosyl transferase, family 2
EGM66_RS11650	COG0156	8-amino-7-oxononanoate synthase activity
EGM66_RS11660	COG0859	PFAM glycosyl transferase family 9
EGM66_RS11665	COG0859	PFAM glycosyl transferase family 9
EGM66_RS11680	COG1442	glycosyl transferase family 8
EGM66_RS11685	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EGM66_RS11700	COG0515	serine threonine protein kinase
EGM66_RS11705	COG0438	transferase activity, transferring glycosyl groups
EGM66_RS11710	COG0859	PFAM glycosyl transferase family 9
EGM66_RS11715	COG1519	Transferase
EGM66_RS11725	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EGM66_RS11745	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EGM66_RS11770	COG1561	YicC-like family, N-terminal region
EGM66_RS11775	COG3645	SOS response
EGM66_RS11780	COG2860	membrane
EGM66_RS11790	COG0194	GDP metabolic process
EGM66_RS11800	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EGM66_RS11805	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EGM66_RS11810	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EGM66_RS11815	COG0786	glutamate:sodium symporter activity
EGM66_RS11835	COG1940	carbohydrate kinase activity
EGM66_RS11850	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGM66_RS11850	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGM66_RS11855	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGM66_RS11860	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGM66_RS11860	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGM66_RS11860	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGM66_RS11865	COG3711	transcriptional antiterminator
EGM66_RS11875	COG1501	Belongs to the glycosyl hydrolase 31 family
EGM66_RS11880	COG2211	Major facilitator Superfamily
EGM66_RS11890	COG0582	viral genome integration into host DNA
EGM66_RS11905	COG1609	Transcriptional regulator
EGM66_RS11910	COG2271	Major facilitator Superfamily
EGM66_RS11925	COG2814	Major facilitator Superfamily
EGM66_RS11930	COG0697	spore germination
EGM66_RS11935	COG1464	Belongs to the NlpA lipoprotein family
EGM66_RS11945	COG0457	Tetratricopeptide repeat
EGM66_RS11975	COG1388	LysM domain
EGM66_RS11975	COG4932	domain protein
EGM66_RS11975	COG2373	Large extracellular alpha-helical protein
EGM66_RS12005	COG2252	PERMEase
EGM66_RS12015	COG2271	Major facilitator Superfamily
EGM66_RS12020	COG2271	Major facilitator Superfamily
EGM66_RS12025	COG3851	Histidine kinase
EGM66_RS12030	COG2197	response regulator
EGM66_RS12045	COG0440	acetolactate synthase activity
EGM66_RS12050	COG0028	Belongs to the TPP enzyme family
EGM66_RS12065	COG2814	Major facilitator Superfamily
EGM66_RS12070	COG0641	radical SAM
EGM66_RS12080	COG2149	membrane
EGM66_RS12085	COG3119	arylsulfatase activity
EGM66_RS12090	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EGM66_RS12095	COG2207	Transcriptional regulator
EGM66_RS12110	COG2188	Transcriptional regulator
EGM66_RS12130	COG5645	(Lipo)protein
EGM66_RS12135	COG0823	Involved in the tonB-independent uptake of proteins
EGM66_RS12140	COG0644	oxidoreductase
EGM66_RS12145	COG2271	Major facilitator Superfamily
EGM66_RS12155	COG0800	Aldolase
EGM66_RS12160	COG3734	2-keto-3-deoxy-galactonokinase
EGM66_RS12165	COG2186	Transcriptional regulator
EGM66_RS12175	COG0561	phosphatase activity
EGM66_RS12180	COG3753	Protein conserved in bacteria
EGM66_RS12185	COG0187	DNA topoisomerase II activity
EGM66_RS12195	COG0592	DNA-directed DNA polymerase activity
EGM66_RS12250	COG0814	amino acid
EGM66_RS12265	COG2091	lysine biosynthetic process via aminoadipic acid
EGM66_RS12270	COG0431	NADPH-dependent FMN reductase
EGM66_RS12275	COG2252	PERMEase
EGM66_RS12280	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EGM66_RS12315	COG0704	Plays a role in the regulation of phosphate uptake
EGM66_RS12320	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EGM66_RS12325	COG0581	inorganic phosphate transmembrane transporter activity
EGM66_RS12330	COG0573	inorganic phosphate transmembrane transporter activity
EGM66_RS12335	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EGM66_RS12390	COG3312	ion transport
EGM66_RS12405	COG0716	FMN binding
EGM66_RS12410	COG1522	sequence-specific DNA binding
EGM66_RS12460	COG1129	ABC transporter
EGM66_RS12465	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGM66_RS12470	COG1879	ABC-type sugar transport system periplasmic component
EGM66_RS12475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGM66_RS12480	COG1609	Transcriptional regulator
EGM66_RS12485	COG0477	Major facilitator Superfamily
EGM66_RS12490	COG2186	Transcriptional regulator
EGM66_RS12530	COG3085	chromosome segregation
EGM66_RS12535	COG0606	chelatase, subunit chli
EGM66_RS12555	COG3978	acetolactate synthase activity
EGM66_RS12560	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EGM66_RS12570	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EGM66_RS12575	COG0583	DNA-binding transcription factor activity
EGM66_RS12585	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EGM66_RS12590	COG3692	DNA binding
EGM66_RS12595	COG0210	DNA helicase
EGM66_RS12610	COG3118	belongs to the thioredoxin family
EGM66_RS12620	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EGM66_RS12630	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EGM66_RS12635	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
EGM66_RS12640	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EGM66_RS12645	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EGM66_RS12650	COG0456	acetyltransferase
EGM66_RS12655	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EGM66_RS12660	COG2244	polysaccharide biosynthetic process
EGM66_RS12680	COG1113	amino acid transport
EGM66_RS12705	COG0641	radical SAM
EGM66_RS12710	COG3119	arylsulfatase activity
EGM66_RS12715	COG3071	HemY protein
EGM66_RS12720	COG2959	enzyme of heme biosynthesis
EGM66_RS12725	COG1587	Uroporphyrinogen-III synthase
EGM66_RS12735	COG3072	Adenylate cyclase
EGM66_RS12750	COG5567	small periplasmic lipoprotein
EGM66_RS12760	COG3159	Protein conserved in bacteria
EGM66_RS12770	COG1011	Hydrolase
EGM66_RS12775	COG0210	DNA helicase
EGM66_RS12780	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
EGM66_RS12785	COG3698	Phosphodiester glycosidase
EGM66_RS12790	COG0598	Magnesium transport protein CorA
EGM66_RS12805	COG2962	Rard protein
EGM66_RS12810	COG2050	protein possibly involved in aromatic compounds catabolism
EGM66_RS12815	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
EGM66_RS12820	COG0514	ATP-dependent DNA helicase (RecQ)
EGM66_RS12825	COG1280	lysine exporter protein (LysE YggA)
EGM66_RS12830	COG1280	lysine exporter protein (LysE YggA)
EGM66_RS12835	COG2267	carboxylic ester hydrolase activity
EGM66_RS12840	COG0561	phosphatase activity
EGM66_RS12845	COG0697	spore germination
EGM66_RS12850	COG0583	DNA-binding transcription factor activity
EGM66_RS12870	COG3157	Type VI secretion system effector, Hcp
EGM66_RS12875	COG0412	Dienelactone hydrolase
EGM66_RS12880	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
EGM66_RS12885	COG1322	Protein conserved in bacteria
EGM66_RS12895	COG3165	ubiquinone biosynthetic process from chorismate
EGM66_RS12905	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EGM66_RS12915	COG0805	protein transport
EGM66_RS12925	COG0250	Participates in transcription elongation, termination and antitermination
EGM66_RS12930	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EGM66_RS12935	COG0543	2 iron, 2 sulfur cluster binding
EGM66_RS12955	COG1739	Uncharacterized protein family UPF0029
EGM66_RS12960	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EGM66_RS12965	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
EGM66_RS13000	COG1763	Mo-molybdopterin cofactor biosynthetic process
EGM66_RS13005	COG0746	molybdenum cofactor guanylyltransferase activity
EGM66_RS13010	COG3084	Protein conserved in bacteria
EGM66_RS13015	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EGM66_RS13020	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EGM66_RS13035	COG5339	Protein conserved in bacteria
EGM66_RS13040	COG0204	Acyl-transferase
EGM66_RS13050	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EGM66_RS13050	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EGM66_RS13065	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EGM66_RS13075	COG2204	response regulator
EGM66_RS13080	COG3852	Histidine kinase
EGM66_RS13085	COG0174	glutamine synthetase
EGM66_RS13090	COG1217	gtp-binding protein TYPA
EGM66_RS13095	COG2188	Transcriptional regulator
EGM66_RS13100	COG1082	Xylose isomerase domain protein TIM barrel
EGM66_RS13105	COG2271	Major facilitator Superfamily
EGM66_RS13110	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EGM66_RS13115	COG2211	Major facilitator Superfamily
EGM66_RS13120	COG2211	Major facilitator Superfamily
EGM66_RS13125	COG1501	Belongs to the glycosyl hydrolase 31 family
EGM66_RS13135	COG2017	converts alpha-aldose to the beta-anomer
EGM66_RS13140	COG2942	2-epimerase
EGM66_RS13145	COG3684	Belongs to the aldolase LacD family
EGM66_RS13150	COG2084	Dehydrogenase
EGM66_RS13155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGM66_RS13160	COG1349	DNA-binding transcription factor activity
EGM66_RS13165	COG1011	Hydrolase
EGM66_RS13180	COG0456	acetyltransferase
EGM66_RS13200	COG0657	acetylesterase activity
EGM66_RS13205	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
EGM66_RS13230	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EGM66_RS13235	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EGM66_RS13245	COG2864	formate dehydrogenase
EGM66_RS13250	COG0437	4 iron, 4 sulfur cluster binding
EGM66_RS13270	COG3711	transcriptional antiterminator
EGM66_RS13270	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGM66_RS13275	COG1363	Peptidase, m42
EGM66_RS13280	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGM66_RS13280	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGM66_RS13285	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGM66_RS13330	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EGM66_RS13340	COG2258	MOSC domain
EGM66_RS13345	COG2205	protein histidine kinase activity
EGM66_RS13350	COG0745	RESPONSE REGULATOR receiver
EGM66_RS13355	COG3678	ATP-independent chaperone mediated protein folding
EGM66_RS13370	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EGM66_RS13390	COG3152	Membrane
EGM66_RS13395	COG3691	Protein conserved in bacteria
EGM66_RS13400	COG0589	response to stress
EGM66_RS13410	COG1494	fructose-1,6-bisphosphatase
EGM66_RS13420	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EGM66_RS13435	COG1575	Belongs to the MenA family. Type 1 subfamily
EGM66_RS13450	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EGM66_RS13455	COG1609	Transcriptional regulator
EGM66_RS13460	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EGM66_RS13470	COG3209	COG3209 Rhs family protein
EGM66_RS13480	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
EGM66_RS13490	COG0626	cystathionine gamma-synthase activity
EGM66_RS13495	COG0460	homoserine dehydrogenase
EGM66_RS13495	COG0527	aspartate kinase activity
EGM66_RS13505	COG0737	Belongs to the 5'-nucleotidase family
EGM66_RS13510	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EGM66_RS13520	COG0697	spore germination
EGM66_RS13525	COG3738	Protein conserved in bacteria
EGM66_RS13530	COG0371	Dehydrogenase
EGM66_RS13535	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EGM66_RS13540	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGM66_RS13540	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EGM66_RS13540	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGM66_RS13545	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGM66_RS13550	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGM66_RS13555	COG1882	Formate acetyltransferase
EGM66_RS13560	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EGM66_RS13565	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGM66_RS13570	COG2207	Transcriptional regulator
EGM66_RS13575	COG2194	sulfuric ester hydrolase activity
EGM66_RS13590	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EGM66_RS13605	COG0583	DNA-binding transcription factor activity
EGM66_RS13615	COG1309	transcriptional regulator
EGM66_RS13630	COG4206	TonB-dependent receptor
EGM66_RS13665	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EGM66_RS13665	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EGM66_RS13700	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EGM66_RS13705	COG0250	Participates in transcription elongation, termination and antitermination
EGM66_RS13745	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EGM66_RS13755	COG2104	thiamine diphosphate biosynthetic process
EGM66_RS13760	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EGM66_RS13795	COG3068	Protein conserved in bacteria
EGM66_RS13810	COG3678	ATP-independent chaperone mediated protein folding
EGM66_RS13815	COG4191	Histidine kinase
EGM66_RS13820	COG2204	response regulator
EGM66_RS13825	COG0151	Belongs to the GarS family
EGM66_RS13855	COG0456	acetyltransferase
EGM66_RS13865	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EGM66_RS13870	COG2224	Isocitrate lyase
EGM66_RS13885	COG1414	Transcriptional regulator
EGM66_RS13890	COG1410	methionine synthase
EGM66_RS13890	COG0646	methionine synthase
EGM66_RS13895	COG1283	sodium-dependent phosphate transmembrane transporter activity
EGM66_RS13945	COG1187	pseudouridine synthase activity
EGM66_RS13955	COG0527	aspartate kinase activity
EGM66_RS13985	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EGM66_RS14000	COG3833	ABC-type maltose transport systems, permease component
EGM66_RS14005	COG1175	transmembrane transport
EGM66_RS14010	COG2182	Extracellular solute-binding protein
EGM66_RS14015	COG3842	ATPase activity
EGM66_RS14030	COG1357	PFAM Pentapeptide repeats (8 copies)
EGM66_RS14050	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EGM66_RS14060	COG0534	Mate efflux family protein
EGM66_RS14065	COG3237	CsbD-like
EGM66_RS14070	COG0735	belongs to the Fur family
EGM66_RS14080	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EGM66_RS14090	COG0604	alcohol dehydrogenase
EGM66_RS14095	COG0305	Participates in initiation and elongation during chromosome replication
EGM66_RS14100	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EGM66_RS14105	COG1448	Aminotransferase
EGM66_RS14115	COG3700	Belongs to the class B bacterial acid phosphatase family
EGM66_RS14120	COG0432	Pfam Uncharacterised protein family UPF0047
EGM66_RS14125	COG2315	Protein conserved in bacteria
EGM66_RS14130	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EGM66_RS14135	COG0629	single-stranded DNA binding
EGM66_RS14155	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EGM66_RS14160	COG2207	Transcriptional regulator
EGM66_RS14165	COG0789	Transcriptional regulator
EGM66_RS14170	COG2252	PERMEase
EGM66_RS14175	COG0025	NhaP-type Na H and K H
EGM66_RS14180	COG1357	PFAM Pentapeptide repeats (8 copies)
EGM66_RS14190	COG3162	membrane
EGM66_RS14200	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EGM66_RS14210	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
EGM66_RS14215	COG0437	4 iron, 4 sulfur cluster binding
EGM66_RS14220	COG3301	Polysulphide reductase, NrfD
EGM66_RS14225	COG1138	Cytochrome C-type biogenesis protein
EGM66_RS14230	COG3088	subunit of a heme lyase
EGM66_RS14235	COG4235	cytochrome complex assembly
EGM66_RS14240	COG1301	dicarboxylic acid transport
EGM66_RS14245	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
EGM66_RS14260	COG1289	transmembrane transporter activity
EGM66_RS14265	COG1566	PFAM secretion protein HlyD family protein
EGM66_RS14275	COG2015	COG2015, Alkyl sulfatase and related hydrolases
EGM66_RS14280	COG0698	ribose 5-phosphate isomerase
EGM66_RS14290	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EGM66_RS14295	COG0456	acetyltransferase
EGM66_RS14305	COG3454	Phosphonate metabolism
EGM66_RS14310	COG4778	phosphonate C-P lyase system protein PhnL
EGM66_RS14315	COG4107	phosphonate C-P lyase system protein PhnK
EGM66_RS14320	COG3627	carbon phosphorus lyase activity
EGM66_RS14325	COG3626	phosphonate metabolism
EGM66_RS14330	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
EGM66_RS14335	COG3624	Phosphonate C-P lyase system protein PhnG
EGM66_RS14340	COG2188	Transcriptional regulator
EGM66_RS14345	COG3639	organic phosphonate transmembrane transporter activity
EGM66_RS14350	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
EGM66_RS14360	COG2764	glyoxalase bleomycin resistance protein dioxygenase
EGM66_RS14365	COG2824	Alkylphosphonate utilization operon protein PhnA
EGM66_RS14370	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EGM66_RS14380	COG0477	Major facilitator Superfamily
EGM66_RS14390	COG0642	Histidine kinase
EGM66_RS14395	COG0745	RESPONSE REGULATOR receiver
EGM66_RS14400	COG2194	sulfuric ester hydrolase activity
EGM66_RS14405	COG0531	amino acid
EGM66_RS14410	COG2207	Transcriptional regulator
EGM66_RS14415	COG1982	Orn Lys Arg decarboxylase major
EGM66_RS14420	COG2169	Transcriptional regulator
EGM66_RS14425	COG1486	melibiose metabolic process
EGM66_RS14430	COG2211	Major facilitator Superfamily
EGM66_RS14440	COG3647	Membrane
EGM66_RS14445	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EGM66_RS14445	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EGM66_RS14450	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EGM66_RS14455	COG4565	transcriptional regulatory protein
EGM66_RS14460	COG3290	protein histidine kinase activity
EGM66_RS14465	COG3592	Divergent 4Fe-4S mono-cluster
EGM66_RS14470	COG2388	GCN5-related N-acetyl-transferase
EGM66_RS14485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EGM66_RS14490	COG3104	oligopeptide transport
EGM66_RS14495	COG1982	Orn Lys Arg decarboxylase major
EGM66_RS14500	COG0531	amino acid
EGM66_RS14510	COG3710	Transcriptional regulator
EGM66_RS14515	COG2200	EAL domain
EGM66_RS14515	COG2771	luxR family
EGM66_RS14525	COG4584	PFAM Integrase catalytic
EGM66_RS14530	COG1484	DNA-dependent DNA replication
EGM66_RS14565	COG2003	Belongs to the UPF0758 family
EGM66_RS14590	COG2378	regulation of single-species biofilm formation
EGM66_RS14595	COG3596	GTP binding
EGM66_RS14640	COG1757	Na H antiporter
EGM66_RS14645	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EGM66_RS14655	COG2076	Multidrug Resistance protein
EGM66_RS14670	COG4869	propanediol catabolic process
EGM66_RS14680	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EGM66_RS14685	COG1882	Formate acetyltransferase
EGM66_RS14690	COG1454	alcohol dehydrogenase
EGM66_RS14690	COG1012	belongs to the aldehyde dehydrogenase family
EGM66_RS14700	COG1454	alcohol dehydrogenase
EGM66_RS14700	COG1012	belongs to the aldehyde dehydrogenase family
EGM66_RS14745	COG0583	DNA-binding transcription factor activity
EGM66_RS14750	COG2610	gluconate transmembrane transporter activity
EGM66_RS14800	COG2259	Doxx family
EGM66_RS14950	COG2194	sulfuric ester hydrolase activity
EGM66_RS14955	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
EGM66_RS14955	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EGM66_RS14965	COG0582	viral genome integration into host DNA
EGM66_RS14975	COG1309	transcriptional regulator
EGM66_RS14980	COG4232	protein-disulfide reductase activity
EGM66_RS14990	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EGM66_RS14995	COG1027	Aspartate ammonia-lyase
EGM66_RS15000	COG3030	protein affecting phage T7 exclusion by the F plasmid
EGM66_RS15005	COG0531	amino acid
EGM66_RS15030	COG1509	lysine 2,3-aminomutase activity
EGM66_RS15040	COG5510	response to toxic substance
EGM66_RS15045	COG5510	response to toxic substance
EGM66_RS15050	COG2076	Multidrug Resistance protein
EGM66_RS15055	COG3040	lipid binding
EGM66_RS15060	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EGM66_RS15075	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EGM66_RS15080	COG1053	succinate dehydrogenase
EGM66_RS15090	COG0531	amino acid
EGM66_RS15095	COG3264	Mechanosensitive ion channel
EGM66_RS15095	COG1511	domain protein
EGM66_RS15135	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EGM66_RS15140	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EGM66_RS15140	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EGM66_RS15145	COG0802	atpase or kinase
EGM66_RS15150	COG0860	N-Acetylmuramoyl-L-alanine amidase
EGM66_RS15170	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EGM66_RS15175	COG0330	HflC and HflK could
EGM66_RS15180	COG0330	HflC and HflK could
EGM66_RS15185	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
EGM66_RS15200	COG0557	exoribonuclease II activity
EGM66_RS15205	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EGM66_RS15210	COG3789	protein conserved in bacteria
EGM66_RS15215	COG1842	Phage shock protein A
EGM66_RS15225	COG3766	membrane
EGM66_RS15230	COG5463	Belongs to the UPF0441 family
EGM66_RS15235	COG0754	glutathionylspermidine amidase activity
EGM66_RS15240	COG1960	acyl-CoA dehydrogenase activity
EGM66_RS15250	COG3650	response to hydrogen peroxide
EGM66_RS15255	COG1073	alpha beta
EGM66_RS15270	COG3037	sugar-specific permease SgaT UlaA
EGM66_RS15275	COG3414	Phosphotransferase system galactitol-specific IIB component
EGM66_RS15315	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EGM66_RS15335	COG0675	Transposase, IS605 OrfB family
EGM66_RS15345	COG3061	Opacity-associated protein A
EGM66_RS15350	COG0545	Peptidyl-prolyl cis-trans isomerase
EGM66_RS15355	COG1113	amino acid transport
EGM66_RS15365	COG0697	spore germination
EGM66_RS15370	COG0702	epimerase
EGM66_RS15375	COG1733	regulation of RNA biosynthetic process
EGM66_RS15380	COG0737	Belongs to the 5'-nucleotidase family
EGM66_RS15385	COG1218	3'(2'),5'-bisphosphate nucleotidase
EGM66_RS15395	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
EGM66_RS15405	COG1253	flavin adenine dinucleotide binding
EGM66_RS15415	COG0729	surface antigen
EGM66_RS15420	COG2911	Protein conserved in bacteria
EGM66_RS15425	COG2105	PFAM AIG2 family protein
EGM66_RS15430	COG2336	PFAM SpoVT AbrB
EGM66_RS15435	COG2337	Toxic component of a toxin-antitoxin (TA) module
EGM66_RS15440	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EGM66_RS15445	COG1879	ABC-type sugar transport system periplasmic component
EGM66_RS15450	COG1129	ABC transporter
EGM66_RS15455	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGM66_RS15460	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGM66_RS15470	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EGM66_RS15480	COG0312	modulator of DNA gyrase
EGM66_RS15485	COG3783	Cytochrome b(562)
EGM66_RS15495	COG3077	Addiction module antitoxin, RelB DinJ family
EGM66_RS15500	COG2026	Addiction module toxin, RelE StbE family
EGM66_RS15505	COG0602	queuosine metabolic process
EGM66_RS15510	COG1328	CTP reductase activity
EGM66_RS15515	COG0366	Alpha amylase catalytic
EGM66_RS15520	COG1263	PTS System
EGM66_RS15520	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGM66_RS15525	COG1609	Transcriptional regulator
EGM66_RS15535	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EGM66_RS15540	COG0251	oxidation-reduction process
EGM66_RS15560	COG0251	oxidation-reduction process
EGM66_RS15565	COG1028	Short-chain dehydrogenase reductase Sdr
EGM66_RS15570	COG1309	transcriptional regulator
EGM66_RS15575	COG2731	YhcH YjgK YiaL family protein
EGM66_RS15590	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
EGM66_RS15595	COG0456	acetyltransferase
EGM66_RS15600	COG4269	membrane
EGM66_RS15605	COG0525	valine-tRNA ligase activity
EGM66_RS15610	COG2927	DNA polymerase III (CHI subunit)
EGM66_RS15620	COG0795	lipopolysaccharide-transporting ATPase activity
EGM66_RS15625	COG0795	lipopolysaccharide-transporting ATPase activity
EGM66_RS15630	COG0433	COG0433 Predicted ATPase
EGM66_RS15635	COG1609	Transcriptional regulator
EGM66_RS15640	COG2610	gluconate transmembrane transporter activity
EGM66_RS15645	COG1028	Short-chain dehydrogenase reductase Sdr
EGM66_RS15650	COG1063	alcohol dehydrogenase
EGM66_RS15655	COG3265	gluconokinase activity
EGM66_RS15660	COG1064	alcohol dehydrogenase
EGM66_RS15690	COG3385	transposase activity
EGM66_RS15695	COG2814	Major facilitator Superfamily
EGM66_RS15700	COG0673	inositol 2-dehydrogenase activity
EGM66_RS15735	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EGM66_RS15750	COG2085	NADP oxidoreductase coenzyme F420-dependent
EGM66_RS15755	COG1120	ATPase activity
EGM66_RS15760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGM66_RS15765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGM66_RS15770	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EGM66_RS15775	COG4772	TonB-dependent receptor
EGM66_RS15780	COG3712	iron ion homeostasis
EGM66_RS15785	COG1595	DNA-templated transcription, initiation
EGM66_RS15830	COG4372	Transposase
EGM66_RS15835	COG3436	PFAM IS66 Orf2 family protein
EGM66_RS15905	COG4983	Phage plasmid primase, P4 family domain protein
EGM66_RS15915	COG3468	outer membrane autotransporter barrel domain protein
EGM66_RS15945	COG2003	Belongs to the UPF0758 family
EGM66_RS15985	COG2390	Transcriptional regulator
EGM66_RS15990	COG2610	gluconate transmembrane transporter activity
EGM66_RS15995	COG0129	dihydroxy-acid dehydratase activity
EGM66_RS16000	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EGM66_RS16005	COG1414	Transcriptional regulator
EGM66_RS16010	COG1349	DNA-binding transcription factor activity
EGM66_RS16015	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EGM66_RS16020	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGM66_RS16025	COG0434	BtpA family
EGM66_RS16030	COG3775	system Galactitol-specific IIC component
EGM66_RS16035	COG3414	Phosphotransferase system galactitol-specific IIB component
EGM66_RS16040	COG1363	Peptidase, m42
EGM66_RS16050	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EGM66_RS16055	COG3153	acetyltransferase
EGM66_RS16070	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
EGM66_RS16070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EGM66_RS16080	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
EGM66_RS16085	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EGM66_RS16090	COG0582	viral genome integration into host DNA
EGM66_RS16095	COG4974	Belongs to the 'phage' integrase family
EGM66_RS16100	COG3539	Fimbrial protein
EGM66_RS16105	COG3539	Fimbrial protein
EGM66_RS16110	COG3121	Chaperone
EGM66_RS16115	COG3188	usher protein
EGM66_RS16120	COG3539	Fimbrial protein
EGM66_RS16125	COG3539	Fimbrial protein
EGM66_RS16130	COG3539	Fimbrial protein
EGM66_RS16135	COG2610	gluconate transmembrane transporter activity
EGM66_RS16145	COG0246	Mannitol dehydrogenase
EGM66_RS16150	COG2186	Transcriptional regulator
EGM66_RS16170	COG0583	DNA-binding transcription factor activity
EGM66_RS16175	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EGM66_RS16180	COG0700	Nucleoside recognition
EGM66_RS16185	COG3366	ferrous iron transmembrane transporter activity
EGM66_RS16195	COG0477	Major facilitator Superfamily
EGM66_RS16210	COG1924	4 iron, 4 sulfur cluster binding
EGM66_RS16215	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
EGM66_RS16220	COG2733	membrane
EGM66_RS16230	COG5457	Domain of unknown function (DUF1127)
EGM66_RS16245	COG0732	type I restriction modification DNA specificity domain
EGM66_RS16250	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EGM66_RS16255	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
EGM66_RS16260	COG1715	Restriction endonuclease
EGM66_RS16265	COG0523	cobalamin synthesis protein
EGM66_RS16270	COG2879	small protein
EGM66_RS16275	COG1966	Carbon starvation protein
EGM66_RS16280	COG0840	transmembrane signaling receptor activity
EGM66_RS16285	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EGM66_RS16295	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EGM66_RS16300	COG0025	NhaP-type Na H and K H
EGM66_RS16305	COG1802	Transcriptional regulator
EGM66_RS16310	COG1063	alcohol dehydrogenase
EGM66_RS16325	COG1484	DNA-dependent DNA replication
EGM66_RS16340	COG2966	Psort location CytoplasmicMembrane, score
EGM66_RS16345	COG2197	response regulator
EGM66_RS16350	COG2197	response regulator
EGM66_RS16355	COG4114	ferric iron reductase
EGM66_RS16385	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
EGM66_RS16390	COG0456	acetyltransferase
EGM66_RS16395	COG1011	Hydrolase
EGM66_RS16405	COG2823	Periplasmic or secreted lipoprotein
EGM66_RS16415	COG4667	esterase of the alpha-beta hydrolase superfamily
EGM66_RS16420	COG0084	hydrolase, TatD family'
EGM66_RS16425	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EGM66_RS16430	COG1328	CTP reductase activity
EGM66_RS16465	COG3726	membrane protein affecting hemolysin expression
EGM66_RS16470	COG0560	Phosphoserine phosphatase
EGM66_RS16475	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EGM66_RS16480	COG3172	ATPase kinase involved in NAD metabolism
EGM66_RS16480	COG1056	cytidyltransferase-related domain
EGM66_RS16485	COG1902	pentaerythritol trinitrate reductase activity
EGM66_RS16500	COG1028	Short-chain dehydrogenase reductase Sdr
EGM66_RS16510	COG0583	DNA-binding transcription factor activity
EGM66_RS16520	COG0488	(ABC) transporter
EGM66_RS16525	COG0741	lytic transglycosylase activity
EGM66_RS16545	COG2207	Transcriptional regulator
EGM66_RS16545	COG3708	Transcriptional regulator
EGM66_RS16550	COG3045	CreA protein
EGM66_RS16555	COG0745	RESPONSE REGULATOR receiver
EGM66_RS16560	COG2205	protein histidine kinase activity
EGM66_RS16565	COG4452	Inner membrane protein CreD
EGM66_RS16580	COG0745	RESPONSE REGULATOR receiver
EGM66_RS16590	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
EGM66_RS16600	COG0527	aspartate kinase activity
EGM66_RS16600	COG0460	homoserine dehydrogenase
EGM66_RS16610	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EGM66_RS16625	COG1115	amino acid carrier protein
EGM66_RS16635	COG0521	Mo-molybdopterin cofactor biosynthetic process
EGM66_RS16640	COG1584	GPR1 FUN34 yaaH family protein
EGM66_RS16645	COG4735	regulation of single-species biofilm formation
EGM66_RS16675	COG0583	DNA-binding transcription factor activity
EGM66_RS16685	COG3188	usher protein
EGM66_RS16690	COG3121	Chaperone
EGM66_RS16715	COG0196	riboflavin kinase activity
EGM66_RS16730	COG1047	Peptidyl-prolyl cis-trans
EGM66_RS16755	COG0505	Belongs to the CarA family
EGM66_RS16760	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EGM66_RS16810	COG0644	oxidoreductase
EGM66_RS16820	COG2271	Major facilitator Superfamily
EGM66_RS16835	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EGM66_RS16870	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EGM66_RS16880	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EGM66_RS16885	COG1357	PFAM Pentapeptide repeats (8 copies)
EGM66_RS16895	COG0564	pseudouridine synthase activity
EGM66_RS16905	COG0417	DNA replication proofreading
EGM66_RS16910	COG0235	Class ii aldolase
EGM66_RS16925	COG4977	sequence-specific DNA binding
EGM66_RS16930	COG0586	Pfam SNARE associated Golgi protein
EGM66_RS16940	COG1178	ABC-type Fe3 transport system permease component
EGM66_RS16945	COG4143	(ABC) transporter
EGM66_RS16960	COG2814	Major facilitator Superfamily
EGM66_RS16975	COG0473	3-isopropylmalate dehydrogenase activity
EGM66_RS16990	COG0583	DNA-binding transcription factor activity
EGM66_RS16995	COG0028	Belongs to the TPP enzyme family
EGM66_RS17000	COG0440	acetolactate synthase activity
EGM66_RS17010	COG1609	Transcriptional regulator
EGM66_RS17025	COG3116	cell division
EGM66_RS17030	COG0768	penicillin binding
EGM66_RS17035	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EGM66_RS17040	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EGM66_RS17055	COG0772	Belongs to the SEDS family
EGM66_RS17070	COG1181	Belongs to the D-alanine--D-alanine ligase family
EGM66_RS17075	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EGM66_RS17080	COG0849	cell division
EGM66_RS17085	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EGM66_RS17105	COG0494	nUDIX hydrolase
EGM66_RS17120	COG0237	dephospho-CoA kinase activity
EGM66_RS17130	COG1459	type II secretion system
EGM66_RS17135	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EGM66_RS17140	COG4969	Belongs to the N-Me-Phe pilin family
EGM66_RS17145	COG0157	Belongs to the NadC ModD family
EGM66_RS17150	COG3023	N-Acetylmuramoyl-L-alanine amidase
EGM66_RS17155	COG3725	Membrane protein required for beta-lactamase induction
EGM66_RS17160	COG1113	amino acid transport
EGM66_RS17165	COG2186	Transcriptional regulator
EGM66_RS17170	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EGM66_RS17175	COG0508	dehydrogenase complex catalyzes the overall conversion of
EGM66_RS17180	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGM66_RS17185	COG3064	Membrane
EGM66_RS17190	COG1049	propionate catabolic process, 2-methylcitrate cycle
EGM66_RS17220	COG2132	Multicopper oxidase
EGM66_RS17225	COG4993	Dehydrogenase
EGM66_RS17230	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EGM66_RS17235	COG0288	reversible hydration of carbon dioxide
EGM66_RS17240	COG1131	(ABC) transporter
EGM66_RS17245	COG0842	Transport permease protein
EGM66_RS17250	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGM66_RS17255	COG0726	polysaccharide deacetylase
EGM66_RS17265	COG5464	transposase or invertase
EGM66_RS17280	COG3539	Fimbrial protein
EGM66_RS17285	COG3539	Fimbrial protein
EGM66_RS17290	COG3539	Fimbrial protein
EGM66_RS17295	COG3188	usher protein
EGM66_RS17300	COG3121	Chaperone
EGM66_RS17305	COG3539	Fimbrial protein
EGM66_RS17310	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EGM66_RS17315	COG0617	tRNA 3'-terminal CCA addition
EGM66_RS17320	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EGM66_RS17325	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EGM66_RS17335	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EGM66_RS17340	COG1643	Atp-dependent helicase
EGM66_RS17345	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EGM66_RS17350	COG4774	siderophore transport
EGM66_RS17355	COG1120	ATPase activity
EGM66_RS17360	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EGM66_RS17365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGM66_RS17390	COG2860	membrane
EGM66_RS17395	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EGM66_RS17410	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EGM66_RS17415	COG3835	regulator
EGM66_RS17435	COG0024	Methionine aminopeptidase
EGM66_RS17460	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EGM66_RS17465	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EGM66_RS17470	COG0575	Belongs to the CDS family
EGM66_RS17475	COG0750	zinc metalloprotease
EGM66_RS17485	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
EGM66_RS17490	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EGM66_RS17515	COG0587	DNA-directed DNA polymerase activity
EGM66_RS17525	COG1982	Orn Lys Arg decarboxylase major
EGM66_RS17530	COG0346	lactoylglutathione lyase activity
EGM66_RS17535	COG0037	tRNA processing
EGM66_RS17540	COG4568	rho-dependent transcription termination
EGM66_RS17550	COG4681	YaeQ
EGM66_RS17555	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EGM66_RS17560	COG3015	lipoprotein NlpE involved in copper resistance
EGM66_RS17565	COG0791	NLP P60 protein
EGM66_RS17575	COG1720	tRNA m6t6A37 methyltransferase activity
EGM66_RS17585	COG1464	Belongs to the NlpA lipoprotein family
EGM66_RS17590	COG2011	ABC-type metal ion transport system permease component
EGM66_RS17595	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EGM66_RS17600	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EGM66_RS17635	COG0656	L-ascorbic acid biosynthetic process
EGM66_RS17640	COG0583	DNA-binding transcription factor activity
EGM66_RS17650	COG2226	methyltransferase
EGM66_RS17655	COG1388	LysM domain
EGM66_RS17655	COG0741	lytic transglycosylase activity
EGM66_RS17665	COG2226	methyltransferase
EGM66_RS17675	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EGM66_RS17695	COG4104	PAAR repeat-containing protein
EGM66_RS17700	COG3157	Type VI secretion system effector, Hcp
EGM66_RS17790	COG3209	COG3209 Rhs family protein
EGM66_RS17810	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EGM66_RS17820	COG1960	acyl-CoA dehydrogenase activity
EGM66_RS17830	COG0121	glutamine amidotransferase
EGM66_RS17835	COG3034	peptidoglycan biosynthetic process
EGM66_RS17840	COG0791	NLP P60 protein
EGM66_RS17865	COG2161	toxin-antitoxin pair type II binding
EGM66_RS17875	COG0454	-acetyltransferase
EGM66_RS17880	COG1690	Belongs to the RtcB family
EGM66_RS17890	COG2195	Cleaves the N-terminal amino acid of tripeptides
EGM66_RS17910	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EGM66_RS17930	COG0582	viral genome integration into host DNA
EGM66_RS17965	COG0583	DNA-binding transcription factor activity
EGM66_RS17980	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EGM66_RS17985	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EGM66_RS17990	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EGM66_RS17995	COG2080	2 iron, 2 sulfur cluster binding
EGM66_RS18000	COG3477	response to acidic pH
EGM66_RS18005	COG0727	PFAM Uncharacterised protein family (UPF0153)
EGM66_RS18065	COG1902	pentaerythritol trinitrate reductase activity
EGM66_RS18070	COG1073	alpha beta
EGM66_RS18075	COG0583	DNA-binding transcription factor activity
EGM66_RS18085	COG0667	Aldo Keto reductase
EGM66_RS18090	COG0656	L-ascorbic acid biosynthetic process
EGM66_RS18095	COG1388	LysM domain
EGM66_RS18105	COG3708	Transcriptional regulator
EGM66_RS18105	COG2207	Transcriptional regulator
EGM66_RS18110	COG0656	L-ascorbic acid biosynthetic process
EGM66_RS18115	COG3059	membrane
EGM66_RS18125	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGM66_RS18130	COG2207	Transcriptional regulator
EGM66_RS18140	COG1139	Iron-sulfur cluster binding protein
EGM66_RS18145	COG1556	Lactate utilization protein
EGM66_RS18170	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EGM66_RS18175	COG2771	luxR family
EGM66_RS18175	COG2200	EAL domain
EGM66_RS18180	COG0583	DNA-binding transcription factor activity
EGM66_RS18190	COG0666	response to abiotic stimulus
EGM66_RS18200	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EGM66_RS18230	COG0549	Belongs to the carbamate kinase family
EGM66_RS18235	COG0402	S-adenosylhomocysteine deaminase activity
EGM66_RS18245	COG1879	ABC-type sugar transport system periplasmic component
EGM66_RS18250	COG1129	ABC transporter
EGM66_RS18255	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGM66_RS18265	COG1064	alcohol dehydrogenase
EGM66_RS18280	COG1280	lysine exporter protein (LysE YggA)
EGM66_RS18290	COG3829	transcription factor binding
EGM66_RS18295	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EGM66_RS18300	COG0372	Belongs to the citrate synthase family
EGM66_RS18305	COG2079	MmgE PrpD family protein
EGM66_RS18310	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EGM66_RS18315	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EGM66_RS18320	COG0402	S-adenosylhomocysteine deaminase activity
EGM66_RS18325	COG0583	DNA-binding transcription factor activity
EGM66_RS18330	COG0288	reversible hydration of carbon dioxide
EGM66_RS18340	COG2807	transmembrane transport
EGM66_RS18345	COG0110	maltose O-acetyltransferase activity
EGM66_RS18350	COG2223	nitrite transmembrane transporter activity
EGM66_RS18360	COG1609	Transcriptional regulator
EGM66_RS18365	COG1414	Transcriptional regulator
EGM66_RS18400	COG2814	Major facilitator Superfamily
EGM66_RS18405	COG3122	Protein conserved in bacteria
EGM66_RS18435	COG1215	transferase activity, transferring glycosyl groups
EGM66_RS18440	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EGM66_RS18445	COG4521	taurine ABC transporter
EGM66_RS18450	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EGM66_RS18455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EGM66_RS18460	COG2175	clavaminate synthase activity
EGM66_RS18465	COG0113	porphobilinogen synthase activity
EGM66_RS18470	COG3468	outer membrane autotransporter barrel domain protein
EGM66_RS18475	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EGM66_RS18480	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EGM66_RS18485	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
EGM66_RS18505	COG1181	Belongs to the D-alanine--D-alanine ligase family
EGM66_RS18515	COG1785	Belongs to the alkaline phosphatase family
EGM66_RS18525	COG3706	GGDEF domain
EGM66_RS18530	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EGM66_RS18550	COG4126	flavin adenine dinucleotide binding
EGM66_RS18575	COG1940	carbohydrate kinase activity
EGM66_RS18585	COG2814	Major facilitator Superfamily
EGM66_RS18590	COG0419	ATPase involved in DNA repair
EGM66_RS18595	COG0420	3'-5' exonuclease activity
EGM66_RS18600	COG0745	RESPONSE REGULATOR receiver
EGM66_RS18605	COG5002	protein histidine kinase activity
EGM66_RS18610	COG1114	Component of the transport system for branched-chain amino acids
EGM66_RS18625	COG1113	amino acid transport
EGM66_RS18630	COG0366	Alpha amylase catalytic
EGM66_RS18655	COG1862	Preprotein translocase
EGM66_RS18660	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EGM66_RS18665	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EGM66_RS18685	COG1403	HNH endonuclease
EGM66_RS18690	COG3248	Nucleoside-binding outer membrane protein
EGM66_RS18705	COG0675	Transposase, IS605 OrfB family
EGM66_RS18720	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EGM66_RS18720	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EGM66_RS18735	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EGM66_RS18740	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EGM66_RS18750	COG0667	Aldo Keto reductase
EGM66_RS18760	COG0142	geranyltranstransferase activity
EGM66_RS18775	COG0693	protein deglycase activity
EGM66_RS18780	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EGM66_RS18790	COG2814	Major facilitator Superfamily
EGM66_RS18800	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EGM66_RS18805	COG1845	cytochrome c oxidase, subunit III
EGM66_RS18810	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EGM66_RS18815	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EGM66_RS18820	COG2223	nitrite transmembrane transporter activity
EGM66_RS18825	COG3056	Lipoprotein
EGM66_RS18830	COG0271	Belongs to the BolA IbaG family
EGM66_RS18850	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EGM66_RS18855	COG0776	regulation of translation
EGM66_RS18860	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EGM66_RS18865	COG1555	photosystem II stabilization
EGM66_RS18870	COG0824	Thioesterase
EGM66_RS18880	COG4533	DNA binding
EGM66_RS18890	COG1522	sequence-specific DNA binding
EGM66_RS18895	COG1132	(ABC) transporter
EGM66_RS18900	COG1132	(ABC) transporter
EGM66_RS18905	COG0347	Belongs to the P(II) protein family
EGM66_RS18910	COG0004	ammonium transporteR
EGM66_RS18915	COG1946	Acyl-CoA thioesterase
EGM66_RS18920	COG3126	Type III secretion system lipoprotein chaperone (YscW)
EGM66_RS18925	COG3695	enzyme binding
EGM66_RS18935	COG5507	3-demethylubiquinone-9 3-methyltransferase
EGM66_RS18940	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EGM66_RS18950	COG0110	maltose O-acetyltransferase activity
EGM66_RS18965	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGM66_RS18970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGM66_RS18980	COG1196	nuclear chromosome segregation
EGM66_RS18980	COG3264	Mechanosensitive ion channel
EGM66_RS18990	COG3923	Primosomal replication protein n
EGM66_RS18995	COG2832	Protein of unknown function (DUF454)
EGM66_RS19005	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EGM66_RS19040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGM66_RS19050	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EGM66_RS19050	COG4651	solute:proton antiporter activity
EGM66_RS19055	COG2223	nitrite transmembrane transporter activity
EGM66_RS19060	COG0737	Belongs to the 5'-nucleotidase family
EGM66_RS19065	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EGM66_RS19070	COG3735	TraB family
EGM66_RS19075	COG2217	Heavy metal translocating P-type atpase
EGM66_RS19085	COG0531	amino acid
EGM66_RS19110	COG0789	Transcriptional regulator
EGM66_RS19135	COG1585	Membrane protein implicated in regulation of membrane protease activity
EGM66_RS19140	COG0330	HflC and HflK could
EGM66_RS19145	COG4619	ABC transporter
EGM66_RS19150	COG0390	transport system, permease component
EGM66_RS19155	COG3118	belongs to the thioredoxin family
EGM66_RS19160	COG0300	oxidoreductase activity
EGM66_RS19165	COG2755	lipolytic protein G-D-S-L family
EGM66_RS19170	COG4181	ATPase activity
EGM66_RS19175	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EGM66_RS19180	COG3209	COG3209 Rhs family protein
EGM66_RS19210	COG0583	DNA-binding transcription factor activity
EGM66_RS19220	COG1414	Transcriptional regulator
EGM66_RS19225	COG3960	tartronate-semialdehyde synthase activity
EGM66_RS19230	COG3622	Belongs to the hyi family
EGM66_RS19235	COG2084	Dehydrogenase
EGM66_RS19240	COG1953	Uracil, thiamine, allantoin
EGM66_RS19250	COG2233	PERMEase
EGM66_RS19255	COG1929	Belongs to the glycerate kinase type-1 family
EGM66_RS19260	COG3257	ureidoglycine aminohydrolase activity
EGM66_RS19265	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EGM66_RS19275	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EGM66_RS19280	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EGM66_RS19290	COG0549	Belongs to the carbamate kinase family
EGM66_RS19295	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EGM66_RS19300	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EGM66_RS19310	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EGM66_RS19320	COG1988	membrane-bound metal-dependent
EGM66_RS19325	COG2501	S4 domain
EGM66_RS19335	COG3539	Fimbrial protein
EGM66_RS19340	COG3121	Chaperone
EGM66_RS19345	COG3188	usher protein
EGM66_RS19350	COG3539	Fimbrial protein
EGM66_RS19355	COG3539	Fimbrial protein
EGM66_RS19360	COG2197	response regulator
EGM66_RS19370	COG2207	Transcriptional regulator
EGM66_RS19380	COG4783	chaperone-mediated protein folding
EGM66_RS19390	COG5433	transposase activity
EGM66_RS19405	COG3209	COG3209 Rhs family protein
EGM66_RS19405	COG4104	PAAR repeat-containing protein
EGM66_RS19450	COG5002	protein histidine kinase activity
EGM66_RS19455	COG0745	RESPONSE REGULATOR receiver
EGM66_RS19460	COG1538	Outer membrane efflux protein
EGM66_RS19465	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGM66_RS19470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGM66_RS19475	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGM66_RS19480	COG1113	amino acid transport
EGM66_RS19485	COG0668	transmembrane transport
EGM66_RS19490	COG0778	Nitroreductase
EGM66_RS19495	COG2315	Protein conserved in bacteria
EGM66_RS19530	COG2977	Belongs to the P-Pant transferase superfamily
EGM66_RS19535	COG4771	TonB-dependent receptor
EGM66_RS19540	COG2382	esterase
EGM66_RS19545	COG3251	PFAM MbtH domain protein
EGM66_RS19550	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
EGM66_RS19550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EGM66_RS19555	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
EGM66_RS19560	COG1120	ATPase activity
EGM66_RS19565	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGM66_RS19570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGM66_RS19580	COG4592	Periplasmic binding protein
EGM66_RS19585	COG1169	isochorismate synthase
EGM66_RS19590	COG1021	2,3-dihydroxybenzoate-AMP ligase
EGM66_RS19595	COG1535	isochorismatase
EGM66_RS19595	COG3433	isochorismatase activity
EGM66_RS19600	COG1028	Short-chain dehydrogenase reductase Sdr
EGM66_RS19605	COG2050	protein possibly involved in aromatic compounds catabolism
EGM66_RS19610	COG1966	Carbon starvation protein
EGM66_RS19615	COG2879	small protein
EGM66_RS19620	COG0371	Dehydrogenase
EGM66_RS19625	COG0436	Aminotransferase
EGM66_RS19630	COG1475	DNA binding
EGM66_RS19635	COG3969	phosphoadenosine phosphosulfate
EGM66_RS19645	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EGM66_RS19650	COG0450	alkyl hydroperoxide reductase
EGM66_RS19655	COG3634	alkyl hydroperoxide reductase activity
EGM66_RS19660	COG0589	response to stress
EGM66_RS19665	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EGM66_RS19670	COG3719	Belongs to the RNase T2 family
EGM66_RS19675	COG0471	metal ion transport
EGM66_RS19690	COG3051	citrate lyase alpha subunit
EGM66_RS19695	COG2301	Belongs to the HpcH HpaI aldolase family
EGM66_RS19705	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
EGM66_RS19710	COG3290	protein histidine kinase activity
EGM66_RS19715	COG4565	transcriptional regulatory protein
EGM66_RS19720	COG3069	C4-dicarboxylate transmembrane transporter activity
EGM66_RS19740	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EGM66_RS19745	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EGM66_RS19755	COG0583	DNA-binding transcription factor activity
EGM66_RS19770	COG1686	Belongs to the peptidase S11 family
EGM66_RS19775	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EGM66_RS19780	COG0772	Belongs to the SEDS family
EGM66_RS19785	COG0768	penicillin binding
EGM66_RS19795	COG0799	negative regulation of ribosome biogenesis
EGM66_RS19800	COG0406	alpha-ribazole phosphatase activity
EGM66_RS19810	COG1466	dna polymerase III delta subunit
EGM66_RS19825	COG2888	peptidyl-tyrosine sulfation
EGM66_RS19835	COG1126	abc transporter atp-binding protein
EGM66_RS19840	COG0765	amino acid transport
EGM66_RS19845	COG0765	amino acid transport
EGM66_RS19850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGM66_RS19855	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EGM66_RS19860	COG4535	Mg2 and Co2 transporter CorC
EGM66_RS19870	COG1702	phosphate starvation-inducible protein PhoH
EGM66_RS19880	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGM66_RS19920	COG0367	asparagine synthase
EGM66_RS19925	COG0647	UMP catabolic process
EGM66_RS19930	COG1940	carbohydrate kinase activity
EGM66_RS19930	COG1846	Transcriptional regulator
EGM66_RS19935	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EGM66_RS19945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGM66_RS19945	COG1263	PTS System
EGM66_RS19945	COG2190	(PTS) system
EGM66_RS19990	COG0735	belongs to the Fur family
EGM66_RS20000	COG0716	FMN binding
EGM66_RS20010	COG0596	Alpha beta hydrolase
EGM66_RS20015	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
EGM66_RS20020	COG0033	Phosphoglucomutase
EGM66_RS20025	COG0531	amino acid
EGM66_RS20030	COG1982	Orn Lys Arg decarboxylase major
EGM66_RS20045	COG0745	RESPONSE REGULATOR receiver
EGM66_RS20050	COG2205	protein histidine kinase activity
EGM66_RS20080	COG3209	COG3209 Rhs family protein
EGM66_RS20090	COG3209	COG3209 Rhs family protein
EGM66_RS20100	COG3272	Protein of unknown function (DUF1722)
EGM66_RS20105	COG0415	Belongs to the DNA photolyase family
EGM66_RS20115	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EGM66_RS20120	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EGM66_RS20125	COG1984	allophanate hydrolase subunit 2
EGM66_RS20140	COG3180	Ammonia monooxygenase
EGM66_RS20145	COG3539	Fimbrial protein
EGM66_RS20150	COG3121	Chaperone
EGM66_RS20155	COG3188	usher protein
EGM66_RS20160	COG3539	Fimbrial protein
EGM66_RS20165	COG0372	Belongs to the citrate synthase family
EGM66_RS20175	COG2009	succinate dehydrogenase
EGM66_RS20180	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EGM66_RS20185	COG1053	succinate dehydrogenase
EGM66_RS20190	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EGM66_RS20195	COG0567	Dehydrogenase, E1 component
EGM66_RS20200	COG0508	dehydrogenase complex catalyzes the overall conversion of
EGM66_RS20210	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EGM66_RS20215	COG2188	Transcriptional regulator
EGM66_RS20220	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGM66_RS20220	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGM66_RS20220	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGM66_RS20225	COG0383	alpha-mannosidase activity
EGM66_RS20235	COG0583	DNA-binding transcription factor activity
EGM66_RS20240	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
EGM66_RS20245	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EGM66_RS20245	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EGM66_RS20250	COG1301	dicarboxylic acid transport
EGM66_RS20265	COG3799	methylaspartate ammonia-lyase activity
EGM66_RS20270	COG4865	methylaspartate mutase activity
EGM66_RS20280	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EGM66_RS20295	COG1271	oxidase subunit
EGM66_RS20300	COG1294	oxidase, subunit
EGM66_RS20305	COG4890	Cyd operon protein YbgT
EGM66_RS20310	COG3790	cyd operon protein YbgE
EGM66_RS20315	COG0824	Thioesterase
EGM66_RS20320	COG0811	peptide transport
EGM66_RS20325	COG0848	biopolymer transport protein
EGM66_RS20330	COG3064	Membrane
EGM66_RS20340	COG2885	chlorophyll binding
EGM66_RS20345	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
EGM66_RS20395	COG3201	nicotinamide mononucleotide transporter
EGM66_RS20400	COG1230	cation diffusion facilitator family transporter
EGM66_RS20410	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EGM66_RS20420	COG2017	converts alpha-aldose to the beta-anomer
EGM66_RS20430	COG1085	galactose-1-phosphate uridylyltransferase
EGM66_RS20435	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EGM66_RS20440	COG1119	ATPase activity
EGM66_RS20445	COG2005	Transcriptional regulator
EGM66_RS20445	COG3585	molybdate ion transport
EGM66_RS20455	COG0725	ABC transporter, periplasmic molybdate-binding protein
EGM66_RS20460	COG4149	molybdate abc transporter
EGM66_RS20465	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EGM66_RS20470	COG0561	phosphatase activity
EGM66_RS20480	COG0583	DNA-binding transcription factor activity
EGM66_RS20485	COG2828	Protein conserved in bacteria
EGM66_RS20490	COG0471	metal ion transport
EGM66_RS20500	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EGM66_RS20515	COG4677	pectinesterase activity
EGM66_RS20520	COG0582	viral genome integration into host DNA
EGM66_RS20585	COG3723	Recombinational DNA repair protein, rece pathway
EGM66_RS20695	COG3772	lysozyme
EGM66_RS20815	COG5301	cellulose 1,4-beta-cellobiosidase activity
EGM66_RS20840	COG2199	diguanylate cyclase activity
EGM66_RS20845	COG1881	PFAM PEBP family protein
EGM66_RS20850	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EGM66_RS20865	COG2226	methyltransferase
EGM66_RS20870	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EGM66_RS20880	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EGM66_RS20890	COG0521	Mo-molybdopterin cofactor biosynthetic process
EGM66_RS20900	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EGM66_RS20905	COG0314	molybdopterin synthase activity
EGM66_RS20910	COG0670	Belongs to the BI1 family
EGM66_RS20925	COG0670	Belongs to the BI1 family
EGM66_RS20930	COG0392	lysyltransferase activity
EGM66_RS20935	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EGM66_RS20940	COG3568	Endonuclease Exonuclease Phosphatase
EGM66_RS20950	COG0842	Transport permease protein
EGM66_RS20955	COG0842	Transport permease protein
EGM66_RS20960	COG1131	(ABC) transporter
EGM66_RS20970	COG1309	transcriptional regulator
EGM66_RS20975	COG0513	Belongs to the DEAD box helicase family
EGM66_RS20990	COG1199	ATP-dependent helicase activity
EGM66_RS20995	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EGM66_RS21000	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EGM66_RS21010	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EGM66_RS21020	COG4774	siderophore transport
EGM66_RS21035	COG0668	transmembrane transport
EGM66_RS21040	COG1126	abc transporter atp-binding protein
EGM66_RS21045	COG0765	amino acid transport
EGM66_RS21050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGM66_RS21060	COG5006	permease, DMT superfamily
EGM66_RS21070	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EGM66_RS21090	COG2194	sulfuric ester hydrolase activity
EGM66_RS21100	COG1321	iron dependent repressor
EGM66_RS21105	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EGM66_RS21110	COG1376	ErfK ybiS ycfS ynhG family protein
EGM66_RS21115	COG0488	(ABC) transporter
EGM66_RS21125	COG2271	Major facilitator Superfamily
EGM66_RS21140	COG0561	phosphatase activity
EGM66_RS21145	COG1882	Formate acetyltransferase
EGM66_RS21150	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EGM66_RS21155	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EGM66_RS21160	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EGM66_RS21165	COG0303	'Molybdopterin
EGM66_RS21170	COG1446	asparaginase
EGM66_RS21180	COG0747	negative chemotaxis
EGM66_RS21195	COG2200	EAL domain
EGM66_RS21200	COG2199	diguanylate cyclase activity
EGM66_RS21225	COG2133	pyrroloquinoline quinone binding
EGM66_RS21230	COG0625	glutathione transferase activity
EGM66_RS21235	COG1686	Belongs to the peptidase S11 family
EGM66_RS21240	COG1349	DNA-binding transcription factor activity
EGM66_RS21245	COG0671	phosphoesterase, PA-phosphatase related
EGM66_RS21250	COG2814	Major facilitator Superfamily
EGM66_RS21260	COG0561	phosphatase activity
EGM66_RS21265	COG0738	Major facilitator superfamily
EGM66_RS21270	COG3226	Transcriptional regulator
EGM66_RS21285	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EGM66_RS21295	COG0778	Nitroreductase
EGM66_RS21310	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EGM66_RS21315	COG3842	ATPase activity
EGM66_RS21320	COG1176	ABC-type spermidine putrescine transport system, permease component I
EGM66_RS21325	COG1177	transmembrane transport
EGM66_RS21335	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EGM66_RS21340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGM66_RS21345	COG4160	amino acid transport
EGM66_RS21350	COG4215	(ABC) transporter
EGM66_RS21355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGM66_RS21360	COG1126	abc transporter atp-binding protein
EGM66_RS21390	COG3023	N-Acetylmuramoyl-L-alanine amidase
EGM66_RS21395	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGM66_RS21400	COG0702	epimerase
EGM66_RS21405	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
EGM66_RS21410	COG0028	Belongs to the TPP enzyme family
EGM66_RS21415	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EGM66_RS21425	COG2431	L-lysine efflux transmembrane transporter activity
EGM66_RS21430	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EGM66_RS21435	COG3593	DNA synthesis involved in DNA repair
EGM66_RS21440	COG2990	Protein conserved in bacteria
EGM66_RS21445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGM66_RS21455	COG1278	Cold shock
EGM66_RS21465	COG0542	response to heat
EGM66_RS21505	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EGM66_RS21510	COG4988	ABC transporter
EGM66_RS21515	COG0492	ferredoxin-NADP+ reductase activity
EGM66_RS21520	COG1522	sequence-specific DNA binding
EGM66_RS21525	COG1674	ftsk spoiiie
EGM66_RS21525	COG1178	ABC-type Fe3 transport system permease component
EGM66_RS21535	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EGM66_RS21545	COG0243	molybdopterin cofactor binding
EGM66_RS21550	COG0437	4 iron, 4 sulfur cluster binding
EGM66_RS21555	COG3302	dmso reductase anchor subunit
EGM66_RS21560	COG1335	isochorismatase
EGM66_RS21570	COG0531	amino acid
EGM66_RS21580	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EGM66_RS21585	COG1882	Formate acetyltransferase
EGM66_RS21590	COG2116	formate transmembrane transporter activity
EGM66_RS21595	COG1944	ATP diphosphatase activity
EGM66_RS21600	COG2323	membrane
EGM66_RS21615	COG0501	Belongs to the peptidase M48B family
EGM66_RS21625	COG0539	negative regulation of cytoplasmic translation
EGM66_RS21635	COG0658	competence protein
EGM66_RS21635	COG2333	competence protein COMEC
EGM66_RS21640	COG1132	(ABC) transporter
EGM66_RS21650	COG3214	Protein conserved in bacteria
EGM66_RS21665	COG3173	Aminoglycoside phosphotransferase
EGM66_RS21670	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EGM66_RS21675	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EGM66_RS21685	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
EGM66_RS21695	COG2989	Protein conserved in bacteria
EGM66_RS21700	COG3108	Peptidase M15
EGM66_RS21705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGM66_RS21710	COG1448	Aminotransferase
EGM66_RS21730	COG0308	aminopeptidase N
EGM66_RS21735	COG1116	anion transmembrane transporter activity
EGM66_RS21740	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EGM66_RS21750	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EGM66_RS21755	COG0431	NADPH-dependent FMN reductase
EGM66_RS21760	COG3539	Fimbrial protein
EGM66_RS21765	COG3121	Chaperone
EGM66_RS21770	COG3188	usher protein
EGM66_RS21775	COG3539	Fimbrial protein
EGM66_RS21780	COG3539	Fimbrial protein
EGM66_RS21785	COG3539	Fimbrial protein
EGM66_RS21790	COG3121	Chaperone
EGM66_RS21805	COG3217	Mosc domain protein beta barrel domain protein
EGM66_RS21805	COG0633	Ferredoxin
EGM66_RS21815	COG0488	(ABC) transporter
EGM66_RS21820	COG2995	paraquat-inducible protein a
EGM66_RS21825	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EGM66_RS21825	COG3008	intermembrane lipid transfer
EGM66_RS21830	COG3009	Protein conserved in bacteria
EGM66_RS21835	COG3130	regulation of translation
EGM66_RS21845	COG1067	ATP-dependent peptidase activity
EGM66_RS21865	COG3070	regulator of competence-specific genes
EGM66_RS21870	COG1289	transmembrane transporter activity
EGM66_RS21875	COG3304	Inner membrane component domain
EGM66_RS21880	COG0210	DNA helicase
EGM66_RS21895	COG1832	CoA-binding protein
EGM66_RS21910	COG1254	Belongs to the acylphosphatase family
EGM66_RS21915	COG2920	part of a sulfur-relay system
EGM66_RS21920	COG0670	Belongs to the BI1 family
EGM66_RS21930	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
EGM66_RS21935	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
EGM66_RS21940	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
EGM66_RS21945	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EGM66_RS21950	COG1999	signal sequence binding
EGM66_RS21955	COG1773	rubredoxin
EGM66_RS21960	COG1271	oxidase subunit
EGM66_RS21965	COG1294	oxidase, subunit
EGM66_RS21980	COG1278	Cold shock
EGM66_RS21985	COG1278	Cold shock
EGM66_RS22005	COG0348	domain, Protein
EGM66_RS22010	COG2198	Histidine kinase
EGM66_RS22010	COG2205	protein histidine kinase activity
EGM66_RS22010	COG0784	Response regulator, receiver
EGM66_RS22015	COG1879	ABC-type sugar transport system periplasmic component
EGM66_RS22020	COG0745	RESPONSE REGULATOR receiver
EGM66_RS22025	COG3005	denitrification pathway
EGM66_RS22030	COG0243	molybdopterin cofactor binding
EGM66_RS22035	COG3381	protein complex oligomerization
EGM66_RS22075	COG3729	General stress protein
EGM66_RS22080	COG2233	PERMEase
EGM66_RS22115	COG1309	transcriptional regulator
EGM66_RS22120	COG0506	proline dehydrogenase activity
EGM66_RS22120	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EGM66_RS22120	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EGM66_RS22130	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EGM66_RS22140	COG2822	iron ion transport
EGM66_RS22150	COG1702	phosphate starvation-inducible protein PhoH
EGM66_RS22155	COG3658	cytochrome
EGM66_RS22160	COG1215	transferase activity, transferring glycosyl groups
EGM66_RS22165	COG1649	PFAM Uncharacterised BCR, COG1649
EGM66_RS22165	COG0726	polysaccharide deacetylase
EGM66_RS22170	COG0457	Tetratricopeptide repeat
EGM66_RS22175	COG3706	GGDEF domain
EGM66_RS22195	COG3381	protein complex oligomerization
EGM66_RS22205	COG1462	curli production assembly transport component CsgG
EGM66_RS22220	COG2197	response regulator
EGM66_RS22245	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EGM66_RS22250	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EGM66_RS22265	COG2943	transferase activity, transferring hexosyl groups
EGM66_RS22270	COG5645	(Lipo)protein
EGM66_RS22285	COG1560	Kdo2-lipid A biosynthetic process
EGM66_RS22300	COG3038	cytochrome b561
EGM66_RS22335	COG2999	glutathione oxidoreductase activity
EGM66_RS22345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EGM66_RS22355	COG0673	inositol 2-dehydrogenase activity
EGM66_RS22360	COG0728	peptidoglycan biosynthetic process
EGM66_RS22365	COG3418	PFAM FlgN family protein
EGM66_RS22370	COG2747	anti-sigma28 factor FlgM
EGM66_RS22375	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
EGM66_RS22380	COG1815	bacterial-type flagellum-dependent cell motility
EGM66_RS22385	COG1558	bacterial-type flagellum-dependent cell motility
EGM66_RS22390	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EGM66_RS22395	COG1749	Flagellar hook protein flgE
EGM66_RS22400	COG4787	bacterial-type flagellum-dependent cell motility
EGM66_RS22405	COG4786	Flagellar basal body rod
EGM66_RS22420	COG1705	Flagellar rod assembly protein muramidase FlgJ
EGM66_RS22420	COG3951	Flagellar rod assembly protein muramidase FlgJ
EGM66_RS22425	COG1256	bacterial-type flagellum assembly
EGM66_RS22430	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EGM66_RS22445	COG1530	ribonuclease E activity
EGM66_RS22455	COG0564	pseudouridine synthase activity
EGM66_RS22460	COG0424	maF-like protein
EGM66_RS22465	COG1399	metal-binding, possibly nucleic acid-binding protein
EGM66_RS22485	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EGM66_RS22490	COG1028	Short-chain dehydrogenase reductase Sdr
EGM66_RS22500	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EGM66_RS22515	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EGM66_RS22520	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EGM66_RS22530	COG0470	DNA polymerase III
EGM66_RS22535	COG0084	hydrolase, TatD family'
EGM66_RS22540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGM66_RS22540	COG1263	PTS System
EGM66_RS22545	COG4773	Receptor
EGM66_RS22550	COG0537	adenosine 5'-monophosphoramidase activity
EGM66_RS22555	COG5633	Lipoprotein
EGM66_RS22560	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
EGM66_RS22580	COG1252	NADH dehydrogenase
EGM66_RS22585	COG3134	Outer membrane lipoprotein
EGM66_RS22590	COG1309	transcriptional regulator
EGM66_RS22620	COG1376	ErfK ybiS ycfS ynhG family protein
EGM66_RS22620	COG1388	LysM domain
EGM66_RS22625	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EGM66_RS22630	COG4763	Acyl-transferase
EGM66_RS22635	COG4591	ABC-type transport system involved in lipoprotein release permease component
EGM66_RS22645	COG4591	ABC-type transport system involved in lipoprotein release permease component
EGM66_RS22655	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EGM66_RS22660	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
EGM66_RS22670	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EGM66_RS22675	COG1177	transmembrane transport
EGM66_RS22680	COG0582	viral genome integration into host DNA
EGM66_RS22690	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EGM66_RS22705	COG3646	Phage regulatory protein
EGM66_RS22720	COG1396	sequence-specific DNA binding
EGM66_RS22745	COG1846	Transcriptional regulator
EGM66_RS22810	COG1403	HNH endonuclease
EGM66_RS22815	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
EGM66_RS22850	COG3772	lysozyme
EGM66_RS22860	COG4220	transposase activity
EGM66_RS22970	COG5301	cellulose 1,4-beta-cellobiosidase activity
EGM66_RS22975	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EGM66_RS22985	COG0500	methyltransferase
EGM66_RS23000	COG3842	ATPase activity
EGM66_RS23010	COG2850	peptidyl-arginine hydroxylation
EGM66_RS23015	COG2205	protein histidine kinase activity
EGM66_RS23025	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EGM66_RS23045	COG1187	pseudouridine synthase activity
EGM66_RS23060	COG0538	isocitrate dehydrogenase activity
EGM66_RS23095	COG5562	phage envelope protein
EGM66_RS23100	COG0789	Transcriptional regulator
EGM66_RS23105	COG2200	EAL domain
EGM66_RS23130	COG2200	EAL domain
EGM66_RS23170	COG3468	outer membrane autotransporter barrel domain protein
EGM66_RS23180	COG2894	cell division
EGM66_RS23205	COG0179	Fumarylacetoacetate (FAA) hydrolase
EGM66_RS23220	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EGM66_RS23225	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EGM66_RS23230	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EGM66_RS23245	COG2719	SpoVR family
EGM66_RS23255	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EGM66_RS23270	COG1619	proteins homologs of microcin C7 resistance protein MccF
EGM66_RS23280	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
EGM66_RS23295	COG0157	Belongs to the NadC ModD family
EGM66_RS23300	COG0500	methyltransferase
EGM66_RS23305	COG1120	ATPase activity
EGM66_RS23310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGM66_RS23315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EGM66_RS23330	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGM66_RS23330	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
EGM66_RS23330	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EGM66_RS23335	COG1461	Dihydroxyacetone kinase
EGM66_RS23340	COG2376	Dihydroxyacetone kinase
EGM66_RS23345	COG3284	Transcriptional regulator
EGM66_RS23350	COG3468	outer membrane autotransporter barrel domain protein
EGM66_RS23355	COG0012	GTP binding
EGM66_RS23370	COG0659	secondary active sulfate transmembrane transporter activity
EGM66_RS23375	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EGM66_RS23400	COG2890	protein-(glutamine-N5) methyltransferase activity
EGM66_RS23405	COG3094	Invasion gene expression up-regulator, SirB
EGM66_RS23410	COG2912	Transglutaminase-like superfamily
EGM66_RS23440	COG0387	Pfam Sodium calcium exchanger
EGM66_RS23445	COG4572	Cation transport regulator
EGM66_RS23450	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
EGM66_RS23455	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
EGM66_RS23460	COG4932	domain protein
EGM66_RS23465	COG2197	response regulator
EGM66_RS23470	COG3850	Histidine kinase
EGM66_RS23475	COG2223	nitrite transmembrane transporter activity
EGM66_RS23480	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EGM66_RS23485	COG1140	nitrate reductase beta subunit
EGM66_RS23490	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EGM66_RS23495	COG2181	nitrate reductase activity
EGM66_RS23535	COG0788	formyltetrahydrofolate deformylase activity
EGM66_RS23545	COG1752	Esterase of the alpha-beta hydrolase superfamily
EGM66_RS23550	COG0745	RESPONSE REGULATOR receiver
EGM66_RS23555	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EGM66_RS23565	COG1435	thymidine kinase activity
EGM66_RS23570	COG1454	alcohol dehydrogenase
EGM66_RS23570	COG1012	belongs to the aldehyde dehydrogenase family
EGM66_RS23575	COG2095	MarC family integral membrane protein
EGM66_RS23580	COG4166	transmembrane transport
EGM66_RS23585	COG0601	transmembrane transport
EGM66_RS23590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EGM66_RS23595	COG0444	Belongs to the ABC transporter superfamily
EGM66_RS23600	COG4608	Belongs to the ABC transporter superfamily
EGM66_RS23620	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EGM66_RS23625	COG2350	Protein conserved in bacteria
EGM66_RS23635	COG1607	acyl-coa hydrolase
EGM66_RS23655	COG3047	cAMP biosynthetic process
EGM66_RS23660	COG3685	Protein conserved in bacteria
EGM66_RS23665	COG3685	Protein conserved in bacteria
EGM66_RS23670	COG3729	General stress protein
EGM66_RS23675	COG0159	tryptophan synthase activity
EGM66_RS23685	COG0135	phosphoribosylanthranilate isomerase activity
EGM66_RS23685	COG0134	indole-3-glycerol-phosphate synthase activity
EGM66_RS23690	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EGM66_RS23690	COG0512	Glutamine amidotransferase of anthranilate synthase
EGM66_RS23695	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EGM66_RS23705	COG0613	PHP domain protein
EGM66_RS23710	COG0009	L-threonylcarbamoyladenylate synthase
EGM66_RS23715	COG4907	membrane protein (DUF2207)
EGM66_RS23720	COG1187	pseudouridine synthase activity
EGM66_RS23735	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
EGM66_RS23740	COG1028	Short-chain dehydrogenase reductase Sdr
EGM66_RS23745	COG0616	signal peptide processing
EGM66_RS23765	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EGM66_RS23770	COG0583	DNA-binding transcription factor activity
EGM66_RS23790	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EGM66_RS23800	COG0671	phosphoesterase, PA-phosphatase related
EGM66_RS23805	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
EGM66_RS23810	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EGM66_RS23820	COG0023	Translation Initiation Factor
EGM66_RS23830	COG1349	DNA-binding transcription factor activity
EGM66_RS23840	COG5001	Diguanylate cyclase
EGM66_RS23855	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EGM66_RS23855	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EGM66_RS23860	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EGM66_RS23870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGM66_RS23885	COG2814	Major facilitator Superfamily
EGM66_RS23890	COG4172	Belongs to the ABC transporter superfamily
EGM66_RS23895	COG4172	Belongs to the ABC transporter superfamily
EGM66_RS23900	COG4171	peptide transport system, permease
EGM66_RS23905	COG4168	peptide transport system, permease
EGM66_RS23910	COG4166	transmembrane transport
EGM66_RS23920	COG0531	amino acid
EGM66_RS23930	COG0174	glutamine synthetase
EGM66_RS23935	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EGM66_RS23940	COG1396	sequence-specific DNA binding
EGM66_RS23940	COG1917	Cupin 2, conserved barrel domain protein
EGM66_RS23945	COG1012	belongs to the aldehyde dehydrogenase family
EGM66_RS23950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EGM66_RS23955	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EGM66_RS23965	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EGM66_RS23970	COG1842	Phage shock protein A
EGM66_RS23980	COG1983	PspC domain protein
EGM66_RS23990	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EGM66_RS23995	COG0366	Alpha amylase catalytic
EGM66_RS24000	COG1653	transport
EGM66_RS24005	COG1175	transmembrane transport
EGM66_RS24010	COG0395	ABC-type sugar transport system, permease component
EGM66_RS24015	COG1063	alcohol dehydrogenase
EGM66_RS24020	COG1082	Xylose isomerase domain protein TIM barrel
EGM66_RS24025	COG0673	inositol 2-dehydrogenase activity
EGM66_RS24030	COG1554	hydrolase, family 65, central catalytic
EGM66_RS24040	COG3842	ATPase activity
EGM66_RS24050	COG1609	Transcriptional regulator
EGM66_RS24055	COG3106	COG3106 Predicted ATPase
EGM66_RS24065	COG3283	Transcriptional regulator of aromatic amino acids metabolism
EGM66_RS24070	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EGM66_RS24075	COG4948	Mandelate Racemase Muconate Lactonizing
EGM66_RS24080	COG2866	Carboxypeptidase
EGM66_RS24085	COG0702	epimerase
EGM66_RS24095	COG1073	alpha beta
EGM66_RS24100	COG0583	DNA-binding transcription factor activity
EGM66_RS24105	COG4166	transmembrane transport
EGM66_RS24110	COG0668	transmembrane transport
EGM66_RS24115	COG3182	Iron-regulated membrane protein
EGM66_RS24120	COG0589	response to stress
EGM66_RS24125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EGM66_RS24130	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EGM66_RS24135	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
EGM66_RS24140	COG1473	amidohydrolase
EGM66_RS24145	COG1473	amidohydrolase
EGM66_RS24150	COG0583	DNA-binding transcription factor activity
EGM66_RS24155	COG2207	Transcriptional regulator
EGM66_RS24170	COG2840	Smr protein MutS2
EGM66_RS24175	COG3706	GGDEF domain
EGM66_RS24195	COG0513	Belongs to the DEAD box helicase family
EGM66_RS24205	COG0582	viral genome integration into host DNA
EGM66_RS24225	COG3723	Recombinational DNA repair protein, rece pathway
EGM66_RS24230	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EGM66_RS24285	COG3756	Protein conserved in bacteria
EGM66_RS24290	COG1484	DNA-dependent DNA replication
EGM66_RS24295	COG1846	Transcriptional regulator
EGM66_RS24370	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EGM66_RS24375	COG1475	DNA binding
EGM66_RS24455	COG1196	nuclear chromosome segregation
EGM66_RS24490	COG5301	cellulose 1,4-beta-cellobiosidase activity
EGM66_RS24515	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EGM66_RS24530	COG0477	Major facilitator Superfamily
EGM66_RS24535	COG0246	Mannitol dehydrogenase
EGM66_RS24545	COG1802	Transcriptional regulator
EGM66_RS24550	COG4221	oxidoreductase activity
EGM66_RS24555	COG0339	signal peptide processing
EGM66_RS24560	COG3111	PFAM Bacterial OB fold (BOF) protein
EGM66_RS24565	COG3706	GGDEF domain
EGM66_RS24575	COG2814	Major facilitator Superfamily
EGM66_RS24580	COG0697	spore germination
EGM66_RS24585	COG2188	Transcriptional regulator
EGM66_RS24595	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EGM66_RS24600	COG1447	Phosphotransferase system cellobiose-specific component IIA
EGM66_RS24610	COG2723	6-phospho-beta-galactosidase activity
EGM66_RS24620	COG4977	sequence-specific DNA binding
EGM66_RS24625	COG1846	Transcriptional regulator
EGM66_RS24645	COG0583	DNA-binding transcription factor activity
EGM66_RS24650	COG1012	belongs to the aldehyde dehydrogenase family
EGM66_RS24655	COG2066	Belongs to the glutaminase family
EGM66_RS24665	COG2199	diguanylate cyclase activity
EGM66_RS24675	COG3781	membrane
EGM66_RS24740	COG1396	sequence-specific DNA binding
EGM66_RS24745	COG3550	peptidyl-serine autophosphorylation
EGM66_RS24775	COG2249	NAD(P)H dehydrogenase (quinone) activity
EGM66_RS24780	COG0667	Aldo Keto reductase
EGM66_RS24810	COG3539	Fimbrial protein
EGM66_RS24820	COG3188	usher protein
EGM66_RS24825	COG3539	Fimbrial protein
EGM66_RS24830	COG3539	Fimbrial protein
EGM66_RS24835	COG3539	Fimbrial protein
EGM66_RS24840	COG0243	molybdopterin cofactor binding
EGM66_RS24855	COG3119	arylsulfatase activity
EGM66_RS24860	COG0641	radical SAM
EGM66_RS24870	COG4178	(ABC) transporter
EGM66_RS24875	COG4771	TonB-dependent receptor
EGM66_RS24880	COG0612	Peptidase, M16
EGM66_RS24890	COG0076	glutamate decarboxylase activity
EGM66_RS24895	COG0531	amino acid
EGM66_RS24900	COG1649	PFAM Uncharacterised BCR, COG1649
EGM66_RS24910	COG2200	EAL domain
EGM66_RS24910	COG2202	Pas domain
EGM66_RS24910	COG2199	diguanylate cyclase activity
EGM66_RS24915	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
EGM66_RS24920	COG0747	negative chemotaxis
EGM66_RS24925	COG0601	transmembrane transport
EGM66_RS24930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EGM66_RS24935	COG0444	Belongs to the ABC transporter superfamily
EGM66_RS24940	COG4608	Belongs to the ABC transporter superfamily
EGM66_RS24945	COG1764	response to oxidative stress
EGM66_RS24965	COG1064	alcohol dehydrogenase
EGM66_RS24970	COG3093	addiction module antidote protein HigA
EGM66_RS24985	COG2864	formate dehydrogenase
EGM66_RS24990	COG0437	4 iron, 4 sulfur cluster binding
EGM66_RS25000	COG0697	spore germination
EGM66_RS25015	COG4886	Leucine-rich repeat (LRR) protein
EGM66_RS25020	COG2223	nitrite transmembrane transporter activity
EGM66_RS25025	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EGM66_RS25030	COG1140	nitrate reductase beta subunit
EGM66_RS25035	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EGM66_RS25040	COG2181	nitrate reductase activity
EGM66_RS25045	COG0384	phenazine biosynthesis protein PhzF
EGM66_RS25050	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EGM66_RS25055	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EGM66_RS25065	COG2015	COG2015, Alkyl sulfatase and related hydrolases
EGM66_RS25070	COG2203	Gaf domain
EGM66_RS25070	COG4251	negative regulation of phosphorylation
EGM66_RS25070	COG5001	Diguanylate cyclase
EGM66_RS25070	COG3706	GGDEF domain
EGM66_RS25090	COG3209	COG3209 Rhs family protein
EGM66_RS25105	COG0625	glutathione transferase activity
EGM66_RS25110	COG1113	amino acid transport
EGM66_RS25115	COG3391	amine dehydrogenase activity
EGM66_RS25120	COG4772	TonB-dependent receptor
EGM66_RS25125	COG1802	Transcriptional regulator
EGM66_RS25130	COG2130	NADP-dependent
EGM66_RS25135	COG1247	-acetyltransferase
EGM66_RS25140	COG3238	Protein conserved in bacteria
EGM66_RS25165	COG1177	transmembrane transport
EGM66_RS25170	COG1176	ABC-type spermidine putrescine transport system, permease component I
EGM66_RS25175	COG3842	ATPase activity
EGM66_RS25180	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EGM66_RS25185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EGM66_RS25190	COG1598	PFAM Uncharacterised protein family UPF0150
EGM66_RS25195	COG1724	mRNA binding
EGM66_RS25205	COG0826	peptidase U32
EGM66_RS25210	COG1396	sequence-specific DNA binding
EGM66_RS25215	COG3135	benzoate transporter
EGM66_RS25235	COG0500	methyltransferase
EGM66_RS25240	COG1275	C4-dicarboxylate transporter malic acid transport protein
EGM66_RS25245	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EGM66_RS25250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EGM66_RS25255	COG2841	Protein conserved in bacteria
EGM66_RS25265	COG5383	Protein conserved in bacteria
EGM66_RS25270	COG0583	DNA-binding transcription factor activity
EGM66_RS25275	COG0840	transmembrane signaling receptor activity
EGM66_RS25295	COG3038	cytochrome b561
EGM66_RS25300	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EGM66_RS25305	COG1012	belongs to the aldehyde dehydrogenase family
EGM66_RS25310	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EGM66_RS25330	COG1643	Atp-dependent helicase
EGM66_RS25340	COG0671	phosphoesterase, PA-phosphatase related
EGM66_RS25340	COG2453	phosphatase
EGM66_RS25345	COG2267	carboxylic ester hydrolase activity
EGM66_RS25355	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EGM66_RS25365	COG0667	Aldo Keto reductase
EGM66_RS25375	COG3784	Protein of unknown function (DUF1318)
EGM66_RS25385	COG2911	Protein conserved in bacteria
EGM66_RS25390	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EGM66_RS25395	COG3187	Heat shock protein
EGM66_RS25400	COG3042	response to heat
EGM66_RS25405	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EGM66_RS25405	COG1013	pyruvate-flavodoxin oxidoreductase activity
EGM66_RS25405	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EGM66_RS25405	COG0674	pyruvate-flavodoxin oxidoreductase activity
EGM66_RS25410	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EGM66_RS25415	COG0589	response to stress
EGM66_RS25425	COG1121	(ABC) transporter
EGM66_RS25430	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EGM66_RS25435	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EGM66_RS25465	COG5301	cellulose 1,4-beta-cellobiosidase activity
EGM66_RS25510	COG1196	nuclear chromosome segregation
EGM66_RS25560	COG1030	water channel activity
EGM66_RS25580	COG4220	transposase activity
EGM66_RS25590	COG5562	phage envelope protein
EGM66_RS25615	COG1278	Cold shock
EGM66_RS25625	COG3772	lysozyme
EGM66_RS25640	COG1278	Cold shock
EGM66_RS25645	COG1278	Cold shock
EGM66_RS25655	COG0484	heat shock protein binding
EGM66_RS25660	COG1403	HNH endonuclease
EGM66_RS25680	COG2026	Addiction module toxin, RelE StbE family
EGM66_RS25685	COG3077	Addiction module antitoxin, RelB DinJ family
EGM66_RS25700	COG2801	Transposase and inactivated derivatives
EGM66_RS25715	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EGM66_RS25725	COG1846	Transcriptional regulator
EGM66_RS25740	COG1396	sequence-specific DNA binding
EGM66_RS25765	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EGM66_RS25775	COG0582	viral genome integration into host DNA
EGM66_RS25785	COG1063	alcohol dehydrogenase
EGM66_RS25790	COG4948	Mandelate Racemase Muconate Lactonizing
EGM66_RS25805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EGM66_RS25820	COG0243	molybdopterin cofactor binding
EGM66_RS25825	COG0243	molybdopterin cofactor binding
EGM66_RS25830	COG0437	4 iron, 4 sulfur cluster binding
EGM66_RS25835	COG3302	dmso reductase anchor subunit
EGM66_RS25840	COG3381	protein complex oligomerization
EGM66_RS25850	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EGM66_RS25855	COG1940	carbohydrate kinase activity
EGM66_RS25860	COG0583	DNA-binding transcription factor activity
EGM66_RS25865	COG2814	Major facilitator Superfamily
EGM66_RS25880	COG3591	Belongs to the peptidase S1B family
EGM66_RS25900	COG0628	permease
EGM66_RS25905	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EGM66_RS25910	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EGM66_RS25920	COG0531	amino acid
EGM66_RS25930	COG3136	membrane protein required for alginate biosynthesis
EGM66_RS25935	COG0745	RESPONSE REGULATOR receiver
EGM66_RS25940	COG2205	protein histidine kinase activity
EGM66_RS25950	COG0114	fumarate hydratase activity
EGM66_RS25955	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EGM66_RS25955	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EGM66_RS25960	COG1482	cell wall glycoprotein biosynthetic process
EGM66_RS25965	COG5339	Protein conserved in bacteria
EGM66_RS25980	COG3250	beta-galactosidase activity
EGM66_RS25985	COG1309	transcriptional regulator
EGM66_RS25990	COG1028	Short-chain dehydrogenase reductase Sdr
EGM66_RS25995	COG1609	Transcriptional regulator
EGM66_RS26000	COG1263	PTS System
EGM66_RS26000	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGM66_RS26005	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EGM66_RS26015	COG0673	inositol 2-dehydrogenase activity
EGM66_RS26055	COG4659	FMN binding
EGM66_RS26065	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EGM66_RS26070	COG3104	oligopeptide transport
EGM66_RS26075	COG0625	glutathione transferase activity
EGM66_RS26080	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EGM66_RS26095	COG3895	Periplasmic Protein
EGM66_RS26105	COG3133	Outer membrane lipoprotein
EGM66_RS26120	COG1566	PFAM secretion protein HlyD family protein
EGM66_RS26125	COG1289	transmembrane transporter activity
EGM66_RS26130	COG2032	superoxide dismutase activity
EGM66_RS26135	COG4989	oxidoreductase activity
EGM66_RS26140	COG3313	Fe-S protein
EGM66_RS26145	COG1309	transcriptional regulator
EGM66_RS26150	COG1902	pentaerythritol trinitrate reductase activity
EGM66_RS26155	COG0346	lactoylglutathione lyase activity
EGM66_RS26165	COG1201	RNA secondary structure unwinding
EGM66_RS26170	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EGM66_RS26175	COG0791	NLP P60 protein
EGM66_RS26180	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EGM66_RS26185	COG2814	Major facilitator Superfamily
EGM66_RS26200	COG0583	DNA-binding transcription factor activity
EGM66_RS26205	COG2814	Major facilitator Superfamily
EGM66_RS26210	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EGM66_RS26215	COG0307	riboflavin synthase, alpha
EGM66_RS26225	COG3468	outer membrane autotransporter barrel domain protein
EGM66_RS26245	COG4529	Protein conserved in bacteria
EGM66_RS26255	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
EGM66_RS26260	COG0437	4 iron, 4 sulfur cluster binding
EGM66_RS26270	COG2414	aldehyde ferredoxin oxidoreductase
EGM66_RS26275	COG0437	4 iron, 4 sulfur cluster binding
EGM66_RS26285	COG0469	pyruvate kinase activity
EGM66_RS26290	COG4238	major outer membrane lipoprotein
EGM66_RS26295	COG1376	ErfK ybiS ycfS ynhG family protein
EGM66_RS26310	COG0719	Fe-S assembly protein
EGM66_RS26315	COG0396	ATPase activity
EGM66_RS26320	COG0719	Fe-S assembly protein
EGM66_RS26325	COG0316	Belongs to the HesB IscA family
EGM66_RS26335	COG2050	protein possibly involved in aromatic compounds catabolism
EGM66_RS26340	COG0277	FAD linked oxidase domain protein
EGM66_RS26340	COG0247	lactate metabolic process
EGM66_RS26345	COG0628	permease
EGM66_RS26360	COG0738	Major facilitator superfamily
EGM66_RS26365	COG2271	Major facilitator Superfamily
EGM66_RS26380	COG4670	ketone body catabolic process
EGM66_RS26385	COG1960	acyl-CoA dehydrogenase activity
EGM66_RS26390	COG2207	Transcriptional regulator
EGM66_RS26390	COG1917	Cupin 2, conserved barrel domain protein
EGM66_RS26395	COG2086	electron transfer activity
EGM66_RS26400	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EGM66_RS26405	COG0644	oxidoreductase
EGM66_RS26410	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
EGM66_RS26415	COG0318	PFAM AMP-dependent synthetase and ligase
EGM66_RS26420	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EGM66_RS26420	COG0574	Belongs to the PEP-utilizing enzyme family
EGM66_RS26430	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EGM66_RS26435	COG4256	Hemin uptake protein
EGM66_RS26445	COG2200	EAL domain
EGM66_RS26450	COG0791	NLP P60 protein
EGM66_RS26460	COG0386	Belongs to the glutathione peroxidase family
EGM66_RS26520	COG3137	Salt-induced outer membrane protein
EGM66_RS26525	COG1105	Belongs to the carbohydrate kinase PfkB family
EGM66_RS26535	COG3001	Fructosamine kinase
EGM66_RS26545	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EGM66_RS26550	COG1988	membrane-bound metal-dependent
EGM66_RS26555	COG1823	symporter activity
EGM66_RS26570	COG0753	catalase activity
EGM66_RS26575	COG3394	polysaccharide catabolic process
EGM66_RS26580	COG1486	melibiose metabolic process
EGM66_RS26585	COG1917	Cupin 2, conserved barrel domain protein
EGM66_RS26585	COG2169	Transcriptional regulator
EGM66_RS26590	COG1447	Phosphotransferase system cellobiose-specific component IIA
EGM66_RS26595	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EGM66_RS26600	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EGM66_RS26610	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EGM66_RS26620	COG0322	excinuclease ABC activity
EGM66_RS26630	COG3678	ATP-independent chaperone mediated protein folding
EGM66_RS26660	COG0708	Exodeoxyribonuclease III
EGM66_RS26665	COG0398	Pfam SNARE associated Golgi protein
EGM66_RS26675	COG0398	Pfam SNARE associated Golgi protein
EGM66_RS26680	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EGM66_RS26685	COG4134	Bacterial extracellular solute-binding protein
EGM66_RS26690	COG4135	transport system, permease component
EGM66_RS26695	COG4136	ATPase activity
EGM66_RS26700	COG2897	thiosulfate sulfurtransferase activity
EGM66_RS26705	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EGM66_RS26710	COG0494	nUDIX hydrolase
EGM66_RS26720	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EGM66_RS26725	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EGM66_RS26735	COG0778	Nitroreductase
EGM66_RS26740	COG0616	signal peptide processing
EGM66_RS26745	COG0252	asparaginase activity
EGM66_RS26750	COG1335	isochorismatase
EGM66_RS26755	COG2814	Major facilitator Superfamily
EGM66_RS26760	COG1349	DNA-binding transcription factor activity
EGM66_RS26765	COG0667	Aldo Keto reductase
EGM66_RS26770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGM66_RS26775	COG0191	fructose-bisphosphate aldolase activity
EGM66_RS26785	COG2271	Major facilitator Superfamily
EGM66_RS26790	COG1063	alcohol dehydrogenase
EGM66_RS26795	COG3139	Protein of unknown function (DUF1315)
EGM66_RS26805	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EGM66_RS26810	COG0676	glucose-6-phosphate 1-epimerase activity
EGM66_RS26815	COG0656	L-ascorbic acid biosynthetic process
EGM66_RS26820	COG3713	MltA-interacting MipA family protein
EGM66_RS26825	COG2766	serine protein kinase
EGM66_RS26835	COG2199	diguanylate cyclase activity
EGM66_RS26840	COG2199	diguanylate cyclase activity
EGM66_RS26845	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EGM66_RS26860	COG2207	Transcriptional regulator
EGM66_RS26865	COG2807	transmembrane transport
EGM66_RS26870	COG3189	MarR family transcriptional regulator
EGM66_RS26875	COG3042	response to heat
EGM66_RS26880	COG2199	diguanylate cyclase activity
EGM66_RS26880	COG2203	Gaf domain
EGM66_RS26895	COG2261	transglycosylase associated protein
EGM66_RS26905	COG3615	Tellurite resistance protein tehB
EGM66_RS26915	COG0583	DNA-binding transcription factor activity
EGM66_RS26920	COG0473	3-isopropylmalate dehydrogenase activity
EGM66_RS26925	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EGM66_RS26930	COG4638	Rieske (2fe-2S)
EGM66_RS26940	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EGM66_RS26945	COG0318	PFAM AMP-dependent synthetase and ligase
EGM66_RS26950	COG3065	identical protein binding
EGM66_RS26955	COG1214	PFAM Peptidase M22, glycoprotease
EGM66_RS26960	COG1199	ATP-dependent helicase activity
EGM66_RS26965	COG0251	oxidation-reduction process
EGM66_RS26980	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EGM66_RS26990	COG1760	l-serine dehydratase
EGM66_RS26995	COG2200	EAL domain
EGM66_RS27000	COG1253	flavin adenine dinucleotide binding
EGM66_RS27005	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGM66_RS27005	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGM66_RS27010	COG3715	PTS system
EGM66_RS27015	COG3716	PTS system mannose fructose sorbose family IID component
EGM66_RS27030	COG2226	methyltransferase
EGM66_RS27060	COG1414	Transcriptional regulator
EGM66_RS27065	COG2814	Major facilitator Superfamily
EGM66_RS27075	COG0793	Belongs to the peptidase S41A family
EGM66_RS27085	COG1956	GAF domain-containing protein
EGM66_RS27090	COG2995	paraquat-inducible protein a
EGM66_RS27095	COG3008	intermembrane lipid transfer
EGM66_RS27115	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EGM66_RS27125	COG1276	copper resistance
EGM66_RS27130	COG2372	response to copper ion
EGM66_RS27140	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EGM66_RS27145	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EGM66_RS27150	COG1770	oligopeptidase
EGM66_RS27155	COG2979	Protein of unknown function (DUF533)
EGM66_RS27165	COG3141	response to X-ray
EGM66_RS27175	COG0800	Aldolase
EGM66_RS27180	COG0129	dihydroxy-acid dehydratase activity
EGM66_RS27185	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EGM66_RS27190	COG1737	Transcriptional regulator
EGM66_RS27195	COG0469	pyruvate kinase activity
EGM66_RS27200	COG1560	Kdo2-lipid A biosynthetic process
EGM66_RS27205	COG0739	heme binding
EGM66_RS27210	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
EGM66_RS27220	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EGM66_RS27250	COG0217	transcriptional regulatory protein
EGM66_RS27255	COG0494	nUDIX hydrolase
EGM66_RS27265	COG1335	isochorismatase
EGM66_RS27270	COG1801	Protein of unknown function DUF72
EGM66_RS27275	COG3788	relative of glutathione S-transferase, MAPEG superfamily
EGM66_RS27290	COG0243	molybdopterin cofactor binding
EGM66_RS27295	COG3005	denitrification pathway
EGM66_RS27305	COG3102	Protein conserved in bacteria
EGM66_RS27320	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EGM66_RS27325	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EGM66_RS27330	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
EGM66_RS27335	COG0745	RESPONSE REGULATOR receiver
EGM66_RS27345	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EGM66_RS27350	COG0840	transmembrane signaling receptor activity
EGM66_RS27355	COG0840	transmembrane signaling receptor activity
EGM66_RS27360	COG0835	chemotaxis
EGM66_RS27365	COG2198	Histidine kinase
EGM66_RS27365	COG0643	Histidine kinase
EGM66_RS27370	COG1360	Flagellar Motor Protein
EGM66_RS27375	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EGM66_RS27390	COG0589	response to stress
EGM66_RS27400	COG1877	trehalose-phosphatase activity
EGM66_RS27405	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGM66_RS27410	COG1129	ABC transporter
EGM66_RS27415	COG1879	ABC-type sugar transport system periplasmic component
EGM66_RS27420	COG1528	Iron-storage protein
EGM66_RS27440	COG1528	Iron-storage protein
EGM66_RS27450	COG0814	amino acid
EGM66_RS27455	COG3012	SEC-C Motif Domain Protein
EGM66_RS27455	COG3318	Belongs to the UPF0149 family
EGM66_RS27485	COG2197	response regulator
EGM66_RS27500	COG2197	response regulator
EGM66_RS27505	COG1126	abc transporter atp-binding protein
EGM66_RS27510	COG0765	amino acid transport
EGM66_RS27520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGM66_RS27530	COG1191	sigma factor activity
EGM66_RS27540	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EGM66_RS27545	COG1516	flagellar protein fliS
EGM66_RS27555	COG0366	Alpha amylase catalytic
EGM66_RS27565	COG2391	methyltransferase activity
EGM66_RS27570	COG0425	Belongs to the sulfur carrier protein TusA family
EGM66_RS27575	COG2135	peptidase activity
EGM66_RS27580	COG0675	Transposase, IS605 OrfB family
EGM66_RS27590	COG2207	Transcriptional regulator
EGM66_RS27595	COG1881	PFAM PEBP family protein
EGM66_RS27600	COG2076	Multidrug Resistance protein
EGM66_RS27615	COG1766	The M ring may be actively involved in energy transduction
EGM66_RS27620	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EGM66_RS27625	COG1317	bacterial-type flagellum organization
EGM66_RS27630	COG1157	protein secretion by the type III secretion system
EGM66_RS27635	COG2882	bacterial-type flagellum organization
EGM66_RS27640	COG3144	bacterial-type flagellum assembly
EGM66_RS27645	COG1580	Controls the rotational direction of flagella during chemotaxis
EGM66_RS27650	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EGM66_RS27655	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EGM66_RS27660	COG3190	flagellar
EGM66_RS27665	COG1338	Plays a role in the flagellum-specific transport system
EGM66_RS27670	COG1987	bacterial-type flagellum assembly
EGM66_RS27675	COG1684	flagellar biosynthetic protein fliR
EGM66_RS27680	COG2197	response regulator
EGM66_RS27715	COG5475	Uncharacterized small protein (DUF2158)
EGM66_RS27720	COG2354	Protein conserved in bacteria
EGM66_RS27725	COG0697	spore germination
EGM66_RS27730	COG3727	T/G mismatch-specific endonuclease activity
EGM66_RS27735	COG0270	DNA (cytosine-5-)-methyltransferase activity
EGM66_RS27755	COG2205	protein histidine kinase activity
EGM66_RS27760	COG0745	RESPONSE REGULATOR receiver
EGM66_RS27765	COG2351	hydroxyisourate hydrolase activity
EGM66_RS27780	COG3443	Belongs to the bacterial solute-binding protein 9 family
EGM66_RS27805	COG1169	isochorismate synthase
EGM66_RS27810	COG2814	Major facilitator Superfamily
EGM66_RS27815	COG1132	(ABC) transporter
EGM66_RS27830	COG3433	isochorismatase activity
EGM66_RS27830	COG2226	methyltransferase
EGM66_RS27830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EGM66_RS27850	COG1021	2,3-dihydroxybenzoate-AMP ligase