locus-tag	class	description
CXX11_RS00015	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CXX11_RS00020	COG3327	negative regulation of DNA-templated transcription, initiation
CXX11_RS00025	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CXX11_RS00065	COG0667	Aldo Keto reductase
CXX11_RS00075	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CXX11_RS00080	COG4589	Belongs to the CDS family
CXX11_RS00085	COG2267	carboxylic ester hydrolase activity
CXX11_RS00090	COG0671	phosphoesterase, PA-phosphatase related
CXX11_RS00090	COG2453	phosphatase
CXX11_RS00100	COG1643	Atp-dependent helicase
CXX11_RS00105	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CXX11_RS00115	COG1012	belongs to the aldehyde dehydrogenase family
CXX11_RS00120	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CXX11_RS00125	COG3038	cytochrome b561
CXX11_RS00145	COG0840	transmembrane signaling receptor activity
CXX11_RS00150	COG0583	DNA-binding transcription factor activity
CXX11_RS00155	COG5383	Protein conserved in bacteria
CXX11_RS00165	COG2841	Protein conserved in bacteria
CXX11_RS00170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CXX11_RS00175	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CXX11_RS00180	COG1275	C4-dicarboxylate transporter malic acid transport protein
CXX11_RS00185	COG0500	methyltransferase
CXX11_RS00200	COG0675	Transposase, IS605 OrfB family
CXX11_RS00205	COG3135	benzoate transporter
CXX11_RS00210	COG1396	sequence-specific DNA binding
CXX11_RS00215	COG0826	peptidase U32
CXX11_RS00225	COG1724	mRNA binding
CXX11_RS00230	COG1598	PFAM Uncharacterised protein family UPF0150
CXX11_RS00235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CXX11_RS00240	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CXX11_RS00245	COG3842	ATPase activity
CXX11_RS00250	COG1176	ABC-type spermidine putrescine transport system, permease component I
CXX11_RS00255	COG1177	transmembrane transport
CXX11_RS00280	COG3238	Protein conserved in bacteria
CXX11_RS00285	COG1247	-acetyltransferase
CXX11_RS00290	COG2130	NADP-dependent
CXX11_RS00295	COG1802	Transcriptional regulator
CXX11_RS00300	COG4772	TonB-dependent receptor
CXX11_RS00305	COG3391	amine dehydrogenase activity
CXX11_RS00310	COG1113	amino acid transport
CXX11_RS00315	COG0625	glutathione transferase activity
CXX11_RS00330	COG3209	COG3209 Rhs family protein
CXX11_RS00360	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CXX11_RS00365	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CXX11_RS00375	COG2181	nitrate reductase activity
CXX11_RS00380	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CXX11_RS00385	COG1140	nitrate reductase beta subunit
CXX11_RS00390	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CXX11_RS00395	COG2223	nitrite transmembrane transporter activity
CXX11_RS00400	COG4886	Leucine-rich repeat (LRR) protein
CXX11_RS00405	COG4886	Leucine-rich repeat (LRR) protein
CXX11_RS00410	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CXX11_RS00415	COG0697	spore germination
CXX11_RS00420	COG3383	formate dehydrogenase (NAD+) activity
CXX11_RS00420	COG0243	molybdopterin cofactor binding
CXX11_RS00425	COG3383	formate dehydrogenase (NAD+) activity
CXX11_RS00425	COG0243	molybdopterin cofactor binding
CXX11_RS00430	COG0437	4 iron, 4 sulfur cluster binding
CXX11_RS00435	COG2864	formate dehydrogenase
CXX11_RS00440	COG3093	addiction module antidote protein HigA
CXX11_RS00445	COG1064	alcohol dehydrogenase
CXX11_RS00465	COG1764	response to oxidative stress
CXX11_RS00470	COG4608	Belongs to the ABC transporter superfamily
CXX11_RS00475	COG0444	Belongs to the ABC transporter superfamily
CXX11_RS00480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CXX11_RS00485	COG0601	transmembrane transport
CXX11_RS00490	COG0747	negative chemotaxis
CXX11_RS00495	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CXX11_RS00500	COG2199	diguanylate cyclase activity
CXX11_RS00500	COG2202	Pas domain
CXX11_RS00500	COG2200	EAL domain
CXX11_RS00505	COG3706	GGDEF domain
CXX11_RS00510	COG1649	PFAM Uncharacterised BCR, COG1649
CXX11_RS00515	COG0531	amino acid
CXX11_RS00520	COG0076	glutamate decarboxylase activity
CXX11_RS00525	COG0612	Peptidase, M16
CXX11_RS00540	COG4771	TonB-dependent receptor
CXX11_RS00545	COG4178	(ABC) transporter
CXX11_RS00555	COG0641	radical SAM
CXX11_RS00560	COG3119	arylsulfatase activity
CXX11_RS00565	COG2207	Transcriptional regulator
CXX11_RS00575	COG0243	molybdopterin cofactor binding
CXX11_RS00580	COG3539	Fimbrial protein
CXX11_RS00585	COG3539	Fimbrial protein
CXX11_RS00590	COG3539	Fimbrial protein
CXX11_RS00625	COG4128	Pfam Zonular occludens toxin
CXX11_RS00675	COG3550	peptidyl-serine autophosphorylation
CXX11_RS00680	COG1396	sequence-specific DNA binding
CXX11_RS00685	COG3210	domain, Protein
CXX11_RS00685	COG2911	Protein conserved in bacteria
CXX11_RS00700	COG3781	membrane
CXX11_RS00710	COG2199	diguanylate cyclase activity
CXX11_RS00720	COG2066	Belongs to the glutaminase family
CXX11_RS00725	COG1012	belongs to the aldehyde dehydrogenase family
CXX11_RS00730	COG0583	DNA-binding transcription factor activity
CXX11_RS00760	COG1846	Transcriptional regulator
CXX11_RS00765	COG4977	sequence-specific DNA binding
CXX11_RS00775	COG0697	spore germination
CXX11_RS00780	COG2814	Major facilitator Superfamily
CXX11_RS00790	COG3706	GGDEF domain
CXX11_RS00795	COG3111	PFAM Bacterial OB fold (BOF) protein
CXX11_RS00800	COG1546	Belongs to the CinA family
CXX11_RS00805	COG0339	signal peptide processing
CXX11_RS00810	COG4221	oxidoreductase activity
CXX11_RS00815	COG1802	Transcriptional regulator
CXX11_RS00825	COG0246	Mannitol dehydrogenase
CXX11_RS00830	COG0477	Major facilitator Superfamily
CXX11_RS00840	COG4948	Mandelate Racemase Muconate Lactonizing
CXX11_RS00855	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CXX11_RS00870	COG0243	molybdopterin cofactor binding
CXX11_RS00875	COG0243	molybdopterin cofactor binding
CXX11_RS00880	COG0437	4 iron, 4 sulfur cluster binding
CXX11_RS00885	COG3302	dmso reductase anchor subunit
CXX11_RS00900	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CXX11_RS00905	COG1940	carbohydrate kinase activity
CXX11_RS00910	COG0583	DNA-binding transcription factor activity
CXX11_RS00915	COG2814	Major facilitator Superfamily
CXX11_RS00940	COG3591	Belongs to the peptidase S1B family
CXX11_RS00960	COG0628	permease
CXX11_RS00965	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CXX11_RS00970	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CXX11_RS00980	COG0531	amino acid
CXX11_RS00990	COG3136	membrane protein required for alginate biosynthesis
CXX11_RS00995	COG0745	RESPONSE REGULATOR receiver
CXX11_RS01000	COG2205	protein histidine kinase activity
CXX11_RS01010	COG0114	fumarate hydratase activity
CXX11_RS01015	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CXX11_RS01015	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CXX11_RS01020	COG1482	cell wall glycoprotein biosynthetic process
CXX11_RS01025	COG5339	Protein conserved in bacteria
CXX11_RS01040	COG3250	beta-galactosidase activity
CXX11_RS01045	COG1309	transcriptional regulator
CXX11_RS01050	COG1028	Short-chain dehydrogenase reductase Sdr
CXX11_RS01055	COG1609	Transcriptional regulator
CXX11_RS01060	COG1263	PTS System
CXX11_RS01060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXX11_RS01065	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CXX11_RS01075	COG0673	inositol 2-dehydrogenase activity
CXX11_RS01115	COG4659	FMN binding
CXX11_RS01125	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CXX11_RS01130	COG3104	oligopeptide transport
CXX11_RS01135	COG0625	glutathione transferase activity
CXX11_RS01140	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CXX11_RS01155	COG3895	Periplasmic Protein
CXX11_RS01165	COG3133	Outer membrane lipoprotein
CXX11_RS01180	COG1566	PFAM secretion protein HlyD family protein
CXX11_RS01185	COG1289	transmembrane transporter activity
CXX11_RS01190	COG2032	superoxide dismutase activity
CXX11_RS01195	COG4989	oxidoreductase activity
CXX11_RS01200	COG3313	Fe-S protein
CXX11_RS01205	COG1309	transcriptional regulator
CXX11_RS01210	COG1902	pentaerythritol trinitrate reductase activity
CXX11_RS01215	COG0346	lactoylglutathione lyase activity
CXX11_RS01225	COG1201	RNA secondary structure unwinding
CXX11_RS01230	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CXX11_RS01235	COG0791	NLP P60 protein
CXX11_RS01240	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CXX11_RS01245	COG2814	Major facilitator Superfamily
CXX11_RS01260	COG0583	DNA-binding transcription factor activity
CXX11_RS01265	COG2814	Major facilitator Superfamily
CXX11_RS01270	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CXX11_RS01275	COG0307	riboflavin synthase, alpha
CXX11_RS01285	COG3468	outer membrane autotransporter barrel domain protein
CXX11_RS01305	COG4529	Protein conserved in bacteria
CXX11_RS01315	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
CXX11_RS01320	COG0437	4 iron, 4 sulfur cluster binding
CXX11_RS01330	COG2414	aldehyde ferredoxin oxidoreductase
CXX11_RS01350	COG0437	4 iron, 4 sulfur cluster binding
CXX11_RS01360	COG0469	pyruvate kinase activity
CXX11_RS01365	COG4238	major outer membrane lipoprotein
CXX11_RS01370	COG1376	ErfK ybiS ycfS ynhG family protein
CXX11_RS01385	COG0719	Fe-S assembly protein
CXX11_RS01390	COG0396	ATPase activity
CXX11_RS01395	COG0719	Fe-S assembly protein
CXX11_RS01400	COG0316	Belongs to the HesB IscA family
CXX11_RS01410	COG2050	protein possibly involved in aromatic compounds catabolism
CXX11_RS01415	COG0247	lactate metabolic process
CXX11_RS01415	COG0277	FAD linked oxidase domain protein
CXX11_RS01420	COG0628	permease
CXX11_RS01435	COG0738	Major facilitator superfamily
CXX11_RS01440	COG2271	Major facilitator Superfamily
CXX11_RS01455	COG4670	ketone body catabolic process
CXX11_RS01460	COG1960	acyl-CoA dehydrogenase activity
CXX11_RS01465	COG2207	Transcriptional regulator
CXX11_RS01465	COG1917	Cupin 2, conserved barrel domain protein
CXX11_RS01470	COG2086	electron transfer activity
CXX11_RS01475	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CXX11_RS01480	COG0644	oxidoreductase
CXX11_RS01485	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CXX11_RS01490	COG0318	PFAM AMP-dependent synthetase and ligase
CXX11_RS01495	COG0574	Belongs to the PEP-utilizing enzyme family
CXX11_RS01495	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CXX11_RS01505	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CXX11_RS01510	COG4256	Hemin uptake protein
CXX11_RS01520	COG2200	EAL domain
CXX11_RS01525	COG0791	NLP P60 protein
CXX11_RS01535	COG0386	Belongs to the glutathione peroxidase family
CXX11_RS01550	COG0072	phenylalanine-tRNA ligase activity
CXX11_RS01550	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CXX11_RS01595	COG3137	Salt-induced outer membrane protein
CXX11_RS01600	COG1105	Belongs to the carbohydrate kinase PfkB family
CXX11_RS01610	COG3001	Fructosamine kinase
CXX11_RS01620	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CXX11_RS01625	COG1988	membrane-bound metal-dependent
CXX11_RS01630	COG1823	symporter activity
CXX11_RS01645	COG0753	catalase activity
CXX11_RS01655	COG1486	melibiose metabolic process
CXX11_RS01660	COG2169	Transcriptional regulator
CXX11_RS01660	COG1917	Cupin 2, conserved barrel domain protein
CXX11_RS01665	COG1447	Phosphotransferase system cellobiose-specific component IIA
CXX11_RS01670	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CXX11_RS01675	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CXX11_RS01685	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CXX11_RS01695	COG0322	excinuclease ABC activity
CXX11_RS01705	COG3678	ATP-independent chaperone mediated protein folding
CXX11_RS01735	COG0708	Exodeoxyribonuclease III
CXX11_RS01740	COG0398	Pfam SNARE associated Golgi protein
CXX11_RS01750	COG0398	Pfam SNARE associated Golgi protein
CXX11_RS01755	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CXX11_RS01760	COG4134	Bacterial extracellular solute-binding protein
CXX11_RS01765	COG4135	transport system, permease component
CXX11_RS01770	COG4136	ATPase activity
CXX11_RS01775	COG2897	thiosulfate sulfurtransferase activity
CXX11_RS01780	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CXX11_RS01785	COG0494	nUDIX hydrolase
CXX11_RS01795	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CXX11_RS01805	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CXX11_RS01815	COG0778	Nitroreductase
CXX11_RS01820	COG0616	signal peptide processing
CXX11_RS01825	COG0252	asparaginase activity
CXX11_RS01830	COG1335	isochorismatase
CXX11_RS01850	COG1349	DNA-binding transcription factor activity
CXX11_RS01855	COG0667	Aldo Keto reductase
CXX11_RS01860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CXX11_RS01865	COG0191	fructose-bisphosphate aldolase activity
CXX11_RS01870	COG1063	alcohol dehydrogenase
CXX11_RS01875	COG2271	Major facilitator Superfamily
CXX11_RS01885	COG3139	Protein of unknown function (DUF1315)
CXX11_RS01895	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CXX11_RS01900	COG0676	glucose-6-phosphate 1-epimerase activity
CXX11_RS01905	COG0656	L-ascorbic acid biosynthetic process
CXX11_RS01910	COG3713	MltA-interacting MipA family protein
CXX11_RS01915	COG2766	serine protein kinase
CXX11_RS01925	COG2199	diguanylate cyclase activity
CXX11_RS01930	COG2199	diguanylate cyclase activity
CXX11_RS01935	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CXX11_RS01950	COG2207	Transcriptional regulator
CXX11_RS01960	COG3189	MarR family transcriptional regulator
CXX11_RS01965	COG3042	response to heat
CXX11_RS01995	COG2261	transglycosylase associated protein
CXX11_RS02015	COG3615	Tellurite resistance protein tehB
CXX11_RS02025	COG0583	DNA-binding transcription factor activity
CXX11_RS02030	COG0473	3-isopropylmalate dehydrogenase activity
CXX11_RS02035	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CXX11_RS02040	COG4638	Rieske (2fe-2S)
CXX11_RS02045	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CXX11_RS02050	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CXX11_RS02055	COG0318	PFAM AMP-dependent synthetase and ligase
CXX11_RS02060	COG3065	identical protein binding
CXX11_RS02065	COG1214	PFAM Peptidase M22, glycoprotease
CXX11_RS02070	COG1199	ATP-dependent helicase activity
CXX11_RS02075	COG0251	oxidation-reduction process
CXX11_RS02090	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CXX11_RS02100	COG1760	l-serine dehydratase
CXX11_RS02105	COG2200	EAL domain
CXX11_RS02110	COG1253	flavin adenine dinucleotide binding
CXX11_RS02115	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXX11_RS02115	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX11_RS02120	COG3715	PTS system
CXX11_RS02125	COG3716	PTS system mannose fructose sorbose family IID component
CXX11_RS02140	COG2226	methyltransferase
CXX11_RS02170	COG1414	Transcriptional regulator
CXX11_RS02185	COG0793	Belongs to the peptidase S41A family
CXX11_RS02195	COG1956	GAF domain-containing protein
CXX11_RS02200	COG2995	paraquat-inducible protein a
CXX11_RS02205	COG3008	intermembrane lipid transfer
CXX11_RS02225	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CXX11_RS02235	COG1276	copper resistance
CXX11_RS02240	COG2372	response to copper ion
CXX11_RS02250	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CXX11_RS02255	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CXX11_RS02260	COG1770	oligopeptidase
CXX11_RS02265	COG2979	Protein of unknown function (DUF533)
CXX11_RS02275	COG3141	response to X-ray
CXX11_RS02285	COG0800	Aldolase
CXX11_RS02290	COG0129	dihydroxy-acid dehydratase activity
CXX11_RS02295	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CXX11_RS02305	COG0469	pyruvate kinase activity
CXX11_RS02310	COG1560	Kdo2-lipid A biosynthetic process
CXX11_RS02315	COG0739	heme binding
CXX11_RS02320	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CXX11_RS02330	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CXX11_RS02360	COG0217	transcriptional regulatory protein
CXX11_RS02365	COG0494	nUDIX hydrolase
CXX11_RS02375	COG1335	isochorismatase
CXX11_RS02380	COG1801	Protein of unknown function DUF72
CXX11_RS02385	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CXX11_RS02400	COG0243	molybdopterin cofactor binding
CXX11_RS02405	COG3005	denitrification pathway
CXX11_RS02425	COG3102	Protein conserved in bacteria
CXX11_RS02435	COG3755	Protein conserved in bacteria
CXX11_RS02445	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CXX11_RS02450	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CXX11_RS02455	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CXX11_RS02460	COG0745	RESPONSE REGULATOR receiver
CXX11_RS02470	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CXX11_RS02475	COG0840	transmembrane signaling receptor activity
CXX11_RS02480	COG0840	transmembrane signaling receptor activity
CXX11_RS02485	COG0835	chemotaxis
CXX11_RS02490	COG2198	Histidine kinase
CXX11_RS02490	COG0643	Histidine kinase
CXX11_RS02495	COG1360	Flagellar Motor Protein
CXX11_RS02500	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CXX11_RS02515	COG0589	response to stress
CXX11_RS02525	COG1877	trehalose-phosphatase activity
CXX11_RS02530	COG1172	Belongs to the binding-protein-dependent transport system permease family
CXX11_RS02540	COG1879	ABC-type sugar transport system periplasmic component
CXX11_RS02545	COG1528	Iron-storage protein
CXX11_RS02565	COG1528	Iron-storage protein
CXX11_RS02575	COG0814	amino acid
CXX11_RS02580	COG3318	Belongs to the UPF0149 family
CXX11_RS02580	COG3012	SEC-C Motif Domain Protein
CXX11_RS02585	COG4974	Belongs to the 'phage' integrase family
CXX11_RS02670	COG4695	Portal protein
CXX11_RS02755	COG5301	cellulose 1,4-beta-cellobiosidase activity
CXX11_RS02755	COG5301	cellulose 1,4-beta-cellobiosidase activity
CXX11_RS02775	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CXX11_RS02885	COG2197	response regulator
CXX11_RS02905	COG2197	response regulator
CXX11_RS02910	COG1126	abc transporter atp-binding protein
CXX11_RS02915	COG0765	amino acid transport
CXX11_RS02925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXX11_RS02935	COG1191	sigma factor activity
CXX11_RS02945	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CXX11_RS02950	COG1516	flagellar protein fliS
CXX11_RS02960	COG0366	Alpha amylase catalytic
CXX11_RS02970	COG2391	methyltransferase activity
CXX11_RS02975	COG0425	Belongs to the sulfur carrier protein TusA family
CXX11_RS02980	COG2135	peptidase activity
CXX11_RS02985	COG0675	Transposase, IS605 OrfB family
CXX11_RS02995	COG2207	Transcriptional regulator
CXX11_RS03000	COG1881	PFAM PEBP family protein
CXX11_RS03005	COG2076	Multidrug Resistance protein
CXX11_RS03020	COG1766	The M ring may be actively involved in energy transduction
CXX11_RS03025	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CXX11_RS03030	COG1317	bacterial-type flagellum organization
CXX11_RS03035	COG1157	protein secretion by the type III secretion system
CXX11_RS03040	COG2882	bacterial-type flagellum organization
CXX11_RS03045	COG3144	bacterial-type flagellum assembly
CXX11_RS03050	COG1580	Controls the rotational direction of flagella during chemotaxis
CXX11_RS03055	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CXX11_RS03060	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CXX11_RS03065	COG3190	flagellar
CXX11_RS03070	COG1338	Plays a role in the flagellum-specific transport system
CXX11_RS03075	COG1987	bacterial-type flagellum assembly
CXX11_RS03080	COG1684	flagellar biosynthetic protein fliR
CXX11_RS03085	COG2197	response regulator
CXX11_RS03105	COG3706	GGDEF domain
CXX11_RS03110	COG5475	Uncharacterized small protein (DUF2158)
CXX11_RS03115	COG2354	Protein conserved in bacteria
CXX11_RS03120	COG0697	spore germination
CXX11_RS03125	COG3727	T/G mismatch-specific endonuclease activity
CXX11_RS03130	COG0270	DNA (cytosine-5-)-methyltransferase activity
CXX11_RS03135	COG1418	mRNA catabolic process
CXX11_RS03145	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CXX11_RS03160	COG2205	protein histidine kinase activity
CXX11_RS03165	COG0745	RESPONSE REGULATOR receiver
CXX11_RS03170	COG2351	hydroxyisourate hydrolase activity
CXX11_RS03185	COG3443	Belongs to the bacterial solute-binding protein 9 family
CXX11_RS03190	COG3038	cytochrome b561
CXX11_RS03210	COG1388	LysM domain
CXX11_RS03210	COG1470	cell adhesion involved in biofilm formation
CXX11_RS03220	COG0477	Major facilitator Superfamily
CXX11_RS03225	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CXX11_RS03230	COG0217	transcriptional regulatory protein
CXX11_RS03240	COG0534	Mate efflux family protein
CXX11_RS03250	COG0583	DNA-binding transcription factor activity
CXX11_RS03255	COG0583	DNA-binding transcription factor activity
CXX11_RS03265	COG1376	ErfK ybiS ycfS ynhG family protein
CXX11_RS03280	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
CXX11_RS03310	COG4771	TonB-dependent receptor
CXX11_RS03350	COG1349	DNA-binding transcription factor activity
CXX11_RS03355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CXX11_RS03370	COG1735	metal-dependent hydrolase with the TIM-barrel fold
CXX11_RS03410	COG3436	PFAM IS66 Orf2 family protein
CXX11_RS03415	COG4372	Transposase
CXX11_RS03470	COG4584	PFAM Integrase catalytic
CXX11_RS03475	COG1484	DNA-dependent DNA replication
CXX11_RS03535	COG2003	Belongs to the UPF0758 family
CXX11_RS03575	COG4372	Transposase
CXX11_RS03580	COG3436	PFAM IS66 Orf2 family protein
CXX11_RS03600	COG1289	transmembrane transporter activity
CXX11_RS03610	COG1686	Belongs to the peptidase S11 family
CXX11_RS03615	COG2925	Exonuclease
CXX11_RS03620	COG0425	Belongs to the sulfur carrier protein TusA family
CXX11_RS03625	COG2391	methyltransferase activity
CXX11_RS03630	COG0531	amino acid
CXX11_RS03640	COG0583	DNA-binding transcription factor activity
CXX11_RS03645	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CXX11_RS03650	COG4115	mRNA cleavage
CXX11_RS03655	COG2161	toxin-antitoxin pair type II binding
CXX11_RS03680	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CXX11_RS03680	COG0131	Imidazoleglycerol-phosphate dehydratase
CXX11_RS03685	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CXX11_RS03710	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CXX11_RS03715	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CXX11_RS03730	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CXX11_RS03745	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CXX11_RS03765	COG0110	maltose O-acetyltransferase activity
CXX11_RS03775	COG0438	transferase activity, transferring glycosyl groups
CXX11_RS03795	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CXX11_RS03800	COG1091	dTDP-4-dehydrorhamnose reductase activity
CXX11_RS03805	COG1088	dTDP-glucose 4,6-dehydratase activity
CXX11_RS03810	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CXX11_RS03820	COG0438	transferase activity, transferring glycosyl groups
CXX11_RS03825	COG2327	Polysaccharide pyruvyl transferase
CXX11_RS03830	COG2244	polysaccharide biosynthetic process
CXX11_RS03835	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CXX11_RS03840	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CXX11_RS03845	COG0662	Cupin 2, conserved barrel domain protein
CXX11_RS03845	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CXX11_RS03850	COG0297	glycogen (starch) synthase activity
CXX11_RS03855	COG1051	belongs to the nudix hydrolase family
CXX11_RS03860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CXX11_RS03865	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CXX11_RS03870	COG0110	maltose O-acetyltransferase activity
CXX11_RS03875	COG1216	Glycosyl transferase, family 2
CXX11_RS03885	COG0438	transferase activity, transferring glycosyl groups
CXX11_RS03890	COG1045	serine acetyltransferase
CXX11_RS03895	COG0463	Glycosyl transferase, family 2
CXX11_RS03900	COG0489	protein tyrosine kinase activity
CXX11_RS03900	COG3206	protein involved in exopolysaccharide biosynthesis
CXX11_RS03905	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CXX11_RS03910	COG1596	polysaccharide export
CXX11_RS03915	COG1253	flavin adenine dinucleotide binding
CXX11_RS03920	COG2982	Protein involved in outer membrane biogenesis
CXX11_RS03930	COG0572	uridine kinase
CXX11_RS03935	COG3447	MASE1 domain protein
CXX11_RS03935	COG5002	protein histidine kinase activity
CXX11_RS03935	COG5001	Diguanylate cyclase
CXX11_RS03940	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CXX11_RS03945	COG0443	Heat shock 70 kDa protein
CXX11_RS03950	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
CXX11_RS03960	COG0631	protein serine/threonine phosphatase activity
CXX11_RS04025	COG2205	protein histidine kinase activity
CXX11_RS04030	COG0745	RESPONSE REGULATOR receiver
CXX11_RS04040	COG0826	peptidase U32
CXX11_RS04060	COG1063	alcohol dehydrogenase
CXX11_RS04065	COG3775	system Galactitol-specific IIC component
CXX11_RS04070	COG3414	Phosphotransferase system galactitol-specific IIB component
CXX11_RS04075	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX11_RS04090	COG1830	Aldolase
CXX11_RS04095	COG2211	Major facilitator Superfamily
CXX11_RS04100	COG1397	ADP-ribosylglycohydrolase
CXX11_RS04105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CXX11_RS04110	COG2188	Transcriptional regulator
CXX11_RS04115	COG3757	hydrolase, family 25
CXX11_RS04120	COG0351	phosphomethylpyrimidine kinase
CXX11_RS04135	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CXX11_RS04140	COG5455	response to cobalt ion
CXX11_RS04145	COG3539	Fimbrial protein
CXX11_RS04155	COG3121	Chaperone
CXX11_RS04160	COG3539	Fimbrial protein
CXX11_RS04170	COG0489	protein tyrosine kinase activity
CXX11_RS04250	COG4373	Mu-like prophage FluMu protein gp28
CXX11_RS04260	COG2369	cell adhesion
CXX11_RS04380	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CXX11_RS04395	COG4807	Protein conserved in bacteria
CXX11_RS04400	COG3279	Response regulator of the LytR AlgR family
CXX11_RS04405	COG3275	phosphorelay sensor kinase activity
CXX11_RS04410	COG0789	Transcriptional regulator
CXX11_RS04420	COG1174	glycine betaine transport
CXX11_RS04425	COG1125	glycine betaine transport
CXX11_RS04430	COG1174	glycine betaine transport
CXX11_RS04435	COG1732	Glycine betaine
CXX11_RS04440	COG1472	Belongs to the glycosyl hydrolase 3 family
CXX11_RS04445	COG0277	FAD linked oxidase domain protein
CXX11_RS04450	COG1686	Belongs to the peptidase S11 family
CXX11_RS04460	COG0586	Pfam SNARE associated Golgi protein
CXX11_RS04465	COG1028	Short-chain dehydrogenase reductase Sdr
CXX11_RS04480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CXX11_RS04490	COG1346	cytolysis
CXX11_RS04500	COG2949	membrane
CXX11_RS04525	COG0167	dihydroorotate dehydrogenase activity
CXX11_RS04525	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CXX11_RS04530	COG4211	Belongs to the binding-protein-dependent transport system permease family
CXX11_RS04535	COG1129	ABC transporter
CXX11_RS04540	COG1879	ABC-type sugar transport system periplasmic component
CXX11_RS04545	COG1609	Transcriptional regulator
CXX11_RS04550	COG2311	Membrane
CXX11_RS04560	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CXX11_RS04565	COG4771	TonB-dependent receptor
CXX11_RS04570	COG0833	amino acid
CXX11_RS04575	COG0583	DNA-binding transcription factor activity
CXX11_RS04580	COG2855	membrane
CXX11_RS04590	COG1522	sequence-specific DNA binding
CXX11_RS04590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CXX11_RS04595	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CXX11_RS04605	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CXX11_RS04610	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CXX11_RS04615	COG2313	pseudouridylate synthase activity
CXX11_RS04620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CXX11_RS04625	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CXX11_RS04625	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CXX11_RS04625	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CXX11_RS04630	COG1105	Belongs to the carbohydrate kinase PfkB family
CXX11_RS04635	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX11_RS04635	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX11_RS04640	COG2814	Major facilitator Superfamily
CXX11_RS04655	COG0246	Mannitol dehydrogenase
CXX11_RS04660	COG0523	cobalamin synthesis protein
CXX11_RS04665	COG0671	phosphoesterase, PA-phosphatase related
CXX11_RS04670	COG0791	NLP P60 protein
CXX11_RS04675	COG2200	EAL domain
CXX11_RS04680	COG4166	transmembrane transport
CXX11_RS04685	COG4174	ABC transporter (Permease)
CXX11_RS04690	COG4239	(ABC) transporter, permease
CXX11_RS04695	COG4172	Belongs to the ABC transporter superfamily
CXX11_RS04705	COG2814	Major facilitator Superfamily
CXX11_RS04710	COG1187	pseudouridine synthase activity
CXX11_RS04715	COG1061	Type III restriction enzyme res subunit
CXX11_RS04735	COG3083	sulfuric ester hydrolase activity
CXX11_RS04745	COG3468	outer membrane autotransporter barrel domain protein
CXX11_RS04750	COG2197	response regulator
CXX11_RS04755	COG3088	subunit of a heme lyase
CXX11_RS04755	COG4235	cytochrome complex assembly
CXX11_RS04760	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CXX11_RS04765	COG1138	Cytochrome C-type biogenesis protein
CXX11_RS04775	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CXX11_RS04780	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CXX11_RS04785	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CXX11_RS04790	COG4133	protoheme IX ABC transporter activity
CXX11_RS04795	COG3005	denitrification pathway
CXX11_RS04800	COG3043	anaerobic respiration
CXX11_RS04805	COG0348	domain, Protein
CXX11_RS04810	COG0437	4 iron, 4 sulfur cluster binding
CXX11_RS04820	COG3062	negative regulation of establishment of protein localization
CXX11_RS04825	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CXX11_RS04825	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
CXX11_RS04840	COG4615	Cyclic peptide transporter
CXX11_RS04845	COG3145	DNA-N1-methyladenine dioxygenase activity
CXX11_RS04850	COG2169	Transcriptional regulator
CXX11_RS04850	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CXX11_RS04855	COG1477	protein flavinylation
CXX11_RS04860	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CXX11_RS04865	COG0642	Histidine kinase
CXX11_RS04865	COG2198	Histidine kinase
CXX11_RS04870	COG2197	response regulator
CXX11_RS04875	COG0784	Response regulator, receiver
CXX11_RS04875	COG2205	protein histidine kinase activity
CXX11_RS04880	COG3852	Histidine kinase
CXX11_RS04885	COG2204	response regulator
CXX11_RS04890	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CXX11_RS04895	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CXX11_RS04900	COG2031	fatty acid transporter
CXX11_RS04905	COG0183	Belongs to the thiolase family
CXX11_RS04910	COG4676	Protein conserved in bacteria
CXX11_RS04915	COG5445	Predicted secreted protein (DUF2300)
CXX11_RS04925	COG3234	Protein of unknown function (DUF1175)
CXX11_RS04930	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
CXX11_RS04935	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CXX11_RS04945	COG3468	outer membrane autotransporter barrel domain protein
CXX11_RS04950	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CXX11_RS04955	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CXX11_RS04960	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CXX11_RS04965	COG3642	lipopolysaccharide core region biosynthetic process
CXX11_RS04975	COG0584	glycerophosphoryl diester phosphodiesterase
CXX11_RS04980	COG2271	Major facilitator Superfamily
CXX11_RS04985	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CXX11_RS04995	COG0247	lactate metabolic process
CXX11_RS05000	COG5464	transposase or invertase
CXX11_RS05010	COG2271	Major facilitator Superfamily
CXX11_RS05020	COG1414	Transcriptional regulator
CXX11_RS05085	COG0318	PFAM AMP-dependent synthetase and ligase
CXX11_RS05095	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CXX11_RS05110	COG1169	isochorismate synthase
CXX11_RS05115	COG4575	ribosome binding
CXX11_RS05120	COG2153	protein acetylation
CXX11_RS05155	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CXX11_RS05160	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CXX11_RS05170	COG0839	Belongs to the complex I subunit 6 family
CXX11_RS05185	COG1034	ATP synthesis coupled electron transport
CXX11_RS05190	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CXX11_RS05195	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CXX11_RS05215	COG0583	DNA-binding transcription factor activity
CXX11_RS05220	COG0436	Aminotransferase
CXX11_RS05230	COG0471	metal ion transport
CXX11_RS05230	COG0490	domain, Protein
CXX11_RS05235	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CXX11_RS05250	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CXX11_RS05255	COG0857	belongs to the CobB CobQ family
CXX11_RS05255	COG0280	phosphate acetyltransferase
CXX11_RS05260	COG1288	antiporter activity
CXX11_RS05265	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CXX11_RS05270	COG0622	Phosphoesterase
CXX11_RS05275	COG0625	glutathione transferase activity
CXX11_RS05280	COG0625	glutathione transferase activity
CXX11_RS05285	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CXX11_RS05290	COG1090	epimerase
CXX11_RS05300	COG4598	ABC transporter
CXX11_RS05305	COG4160	amino acid transport
CXX11_RS05310	COG4215	(ABC) transporter
CXX11_RS05315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXX11_RS05320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXX11_RS05325	COG0163	prenyltransferase activity
CXX11_RS05330	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CXX11_RS05335	COG1286	toxin biosynthetic process
CXX11_RS05340	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CXX11_RS05345	COG0285	dihydrofolate synthase activity
CXX11_RS05355	COG0586	Pfam SNARE associated Golgi protein
CXX11_RS05365	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CXX11_RS05380	COG2814	Major facilitator Superfamily
CXX11_RS05385	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CXX11_RS05400	COG3101	peptidyl-lysine hydroxylation
CXX11_RS05405	COG0730	response to heat
CXX11_RS05450	COG3539	Fimbrial protein
CXX11_RS05455	COG3539	Fimbrial protein
CXX11_RS05460	COG3539	Fimbrial protein
CXX11_RS05465	COG3121	Chaperone
CXX11_RS05470	COG3188	usher protein
CXX11_RS05475	COG3539	Fimbrial protein
CXX11_RS05480	COG2062	phosphohistidine phosphatase, SixA
CXX11_RS05495	COG3691	Protein conserved in bacteria
CXX11_RS05525	COG2853	Lipoprotein
CXX11_RS05530	COG2116	formate transmembrane transporter activity
CXX11_RS05540	COG0583	DNA-binding transcription factor activity
CXX11_RS05545	COG2610	gluconate transmembrane transporter activity
CXX11_RS05555	COG0477	Major facilitator Superfamily
CXX11_RS05560	COG1566	PFAM secretion protein HlyD family protein
CXX11_RS05565	COG2197	response regulator
CXX11_RS05570	COG0784	Response regulator, receiver
CXX11_RS05570	COG2198	Histidine kinase
CXX11_RS05570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXX11_RS05570	COG2205	protein histidine kinase activity
CXX11_RS05575	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CXX11_RS05580	COG0679	Auxin Efflux Carrier
CXX11_RS05585	COG0028	Belongs to the TPP enzyme family
CXX11_RS05610	COG1560	Kdo2-lipid A biosynthetic process
CXX11_RS05620	COG0436	Aminotransferase
CXX11_RS05625	COG3275	phosphorelay sensor kinase activity
CXX11_RS05630	COG3279	Response regulator of the LytR AlgR family
CXX11_RS05635	COG2207	Transcriptional regulator
CXX11_RS05640	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX11_RS05640	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX11_RS05640	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CXX11_RS05645	COG1363	Peptidase, m42
CXX11_RS05650	COG0006	proline dipeptidase activity
CXX11_RS05655	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CXX11_RS05660	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CXX11_RS05685	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CXX11_RS05695	COG2200	EAL domain
CXX11_RS05695	COG2199	diguanylate cyclase activity
CXX11_RS05710	COG3415	Transposase
CXX11_RS05715	COG3415	Transposase
CXX11_RS05755	COG0583	DNA-binding transcription factor activity
CXX11_RS05760	COG0385	Bile acid
CXX11_RS05765	COG3530	Putative quorum-sensing-regulated virulence factor
CXX11_RS05785	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CXX11_RS05790	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX11_RS05795	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CXX11_RS05800	COG2190	(PTS) system
CXX11_RS05815	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CXX11_RS05820	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CXX11_RS05825	COG4208	sulfate ABC transporter
CXX11_RS05830	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CXX11_RS05835	COG4150	thiosulfate binding
CXX11_RS05840	COG1028	Short-chain dehydrogenase reductase Sdr
CXX11_RS05855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXX11_RS05855	COG1263	PTS System
CXX11_RS05860	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CXX11_RS05865	COG2837	iron assimilation
CXX11_RS05885	COG0860	N-Acetylmuramoyl-L-alanine amidase
CXX11_RS05895	COG2207	Transcriptional regulator
CXX11_RS05900	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CXX11_RS05905	COG4816	utilization protein
CXX11_RS05915	COG4303	Ethanolamine ammonia lyase large subunit
CXX11_RS05920	COG4819	ethanolamine utilization protein
CXX11_RS05925	COG3192	ethanolamine utilization protein
CXX11_RS05940	COG1454	alcohol dehydrogenase
CXX11_RS05945	COG4820	ethanolamine utilization protein (EutJ)
CXX11_RS05950	COG1012	belongs to the aldehyde dehydrogenase family
CXX11_RS05955	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
CXX11_RS05960	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CXX11_RS05965	COG0280	phosphate acetyltransferase
CXX11_RS05970	COG4812	Cobalamin adenosyltransferase
CXX11_RS05975	COG4766	ethanolamine catabolic process
CXX11_RS05980	COG4917	ethanolamine utilization protein
CXX11_RS05985	COG4810	utilization protein
CXX11_RS05990	COG0280	phosphate acetyltransferase
CXX11_RS05990	COG0281	malic enzyme
CXX11_RS05995	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CXX11_RS06000	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CXX11_RS06005	COG5342	invasion associated locus B
CXX11_RS06015	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CXX11_RS06015	COG0493	'glutamate synthase
CXX11_RS06020	COG3850	Histidine kinase
CXX11_RS06025	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CXX11_RS06035	COG1393	Belongs to the ArsC family
CXX11_RS06050	COG0400	carboxylic ester hydrolase activity
CXX11_RS06060	COG2321	neutral zinc metallopeptidase
CXX11_RS06070	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CXX11_RS06080	COG2716	regulation of RNA biosynthetic process
CXX11_RS06085	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CXX11_RS06090	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CXX11_RS06095	COG0651	ATP synthesis coupled electron transport
CXX11_RS06100	COG0650	Formate hydrogenlyase subunit 4
CXX11_RS06105	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CXX11_RS06110	COG4237	Hydrogenase 4 membrane
CXX11_RS06115	COG0651	ATP synthesis coupled electron transport
CXX11_RS06120	COG0651	ATP synthesis coupled electron transport
CXX11_RS06125	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CXX11_RS06125	COG3261	NADH dehydrogenase
CXX11_RS06130	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CXX11_RS06135	COG3260	NADH ubiquinone oxidoreductase 20
CXX11_RS06145	COG3604	Transcriptional regulator
CXX11_RS06150	COG2116	formate transmembrane transporter activity
CXX11_RS06155	COG0628	permease
CXX11_RS06160	COG4783	chaperone-mediated protein folding
CXX11_RS06165	COG1393	Belongs to the ArsC family
CXX11_RS06175	COG2233	PERMEase
CXX11_RS06190	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CXX11_RS06195	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CXX11_RS06200	COG0248	Ppx GppA phosphatase
CXX11_RS06205	COG2200	EAL domain
CXX11_RS06220	COG3133	Outer membrane lipoprotein
CXX11_RS06235	COG0517	IMP dehydrogenase activity
CXX11_RS06235	COG0516	GMP reductase activity
CXX11_RS06245	COG1645	bacterial-type flagellum-dependent swarming motility
CXX11_RS06260	COG2976	Protein conserved in bacteria
CXX11_RS06290	COG4953	penicillin-binding protein 1C
CXX11_RS06295	COG2373	Large extracellular alpha-helical protein
CXX11_RS06300	COG2897	thiosulfate sulfurtransferase activity
CXX11_RS06325	COG2975	iron-sulfur cluster assembly
CXX11_RS06330	COG0633	Ferredoxin
CXX11_RS06350	COG0822	iron-sulfur transferase activity
CXX11_RS06370	COG0483	inositol monophosphate 1-phosphatase activity
CXX11_RS06375	COG1073	alpha beta
CXX11_RS06380	COG3711	transcriptional antiterminator
CXX11_RS06385	COG2814	Major facilitator Superfamily
CXX11_RS06390	COG0583	DNA-binding transcription factor activity
CXX11_RS06395	COG4638	Rieske (2fe-2S)
CXX11_RS06420	COG2259	Doxx family
CXX11_RS06425	COG2017	converts alpha-aldose to the beta-anomer
CXX11_RS06430	COG1063	alcohol dehydrogenase
CXX11_RS06435	COG1172	Belongs to the binding-protein-dependent transport system permease family
CXX11_RS06440	COG1129	ABC transporter
CXX11_RS06445	COG1879	ABC-type sugar transport system periplasmic component
CXX11_RS06450	COG0457	Tetratricopeptide repeat
CXX11_RS06455	COG1940	carbohydrate kinase activity
CXX11_RS06465	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CXX11_RS06465	COG1017	nitric oxide dioxygenase activity
CXX11_RS06470	COG0347	Belongs to the P(II) protein family
CXX11_RS06475	COG2204	response regulator
CXX11_RS06480	COG3170	Tfp pilus assembly protein FimV
CXX11_RS06485	COG2205	protein histidine kinase activity
CXX11_RS06505	COG0560	Phosphoserine phosphatase
CXX11_RS06510	COG1737	Transcriptional regulator
CXX11_RS06515	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CXX11_RS06530	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CXX11_RS06550	COG0681	Belongs to the peptidase S26 family
CXX11_RS06560	COG3086	response to oxidative stress
CXX11_RS06565	COG3026	antisigma factor binding
CXX11_RS06570	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
CXX11_RS06575	COG1595	DNA-templated transcription, initiation
CXX11_RS06585	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CXX11_RS06595	COG0513	Belongs to the DEAD box helicase family
CXX11_RS06600	COG0583	DNA-binding transcription factor activity
CXX11_RS06620	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CXX11_RS06625	COG3118	belongs to the thioredoxin family
CXX11_RS06630	COG3148	PFAM DTW domain containing protein
CXX11_RS06635	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CXX11_RS06635	COG0045	succinate-CoA ligase (ADP-forming) activity
CXX11_RS06635	COG1042	CoA-binding domain protein
CXX11_RS06640	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CXX11_RS06645	COG5544	Lipoprotein
CXX11_RS06650	COG0477	Major facilitator Superfamily
CXX11_RS06675	COG0542	response to heat
CXX11_RS06680	COG1496	oxidoreductase activity
CXX11_RS06685	COG0564	pseudouridine synthase activity
CXX11_RS06690	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CXX11_RS06695	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CXX11_RS06705	COG0077	Prephenate dehydratase
CXX11_RS06705	COG1605	Chorismate mutase
CXX11_RS06710	COG0287	Prephenate dehydrogenase
CXX11_RS06710	COG1605	Chorismate mutase
CXX11_RS06715	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CXX11_RS06730	COG2199	diguanylate cyclase activity
CXX11_RS06735	COG2885	chlorophyll binding
CXX11_RS06760	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CXX11_RS06765	COG4137	Cytochrome C assembly protein
CXX11_RS06770	COG4536	flavin adenine dinucleotide binding
CXX11_RS06790	COG0497	DNA recombination
CXX11_RS06795	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CXX11_RS06805	COG2867	negative regulation of translational initiation
CXX11_RS06820	COG0582	viral genome integration into host DNA
CXX11_RS06875	COG0579	oxidoreductase
CXX11_RS06880	COG1012	belongs to the aldehyde dehydrogenase family
CXX11_RS06885	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CXX11_RS06890	COG1113	amino acid transport
CXX11_RS06895	COG1802	Transcriptional regulator
CXX11_RS06900	COG1652	LysM domain
CXX11_RS06905	COG0401	homolog of Blt101
CXX11_RS06910	COG0640	Transcriptional regulator
CXX11_RS06915	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CXX11_RS06920	COG2916	Histone family protein nucleoid-structuring protein H-NS
CXX11_RS06935	COG4575	ribosome binding
CXX11_RS06940	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CXX11_RS06950	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CXX11_RS06955	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CXX11_RS06965	COG4175	Glycine betaine
CXX11_RS06970	COG4176	ABC-type proline glycine betaine transport system permease component
CXX11_RS06975	COG2113	Glycine betaine
CXX11_RS06985	COG2814	Major facilitator Superfamily
CXX11_RS06990	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CXX11_RS07000	COG1846	Transcriptional regulator
CXX11_RS07010	COG2814	Major facilitator Superfamily
CXX11_RS07025	COG1238	metal cluster binding
CXX11_RS07030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CXX11_RS07055	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CXX11_RS07075	COG1546	Belongs to the CinA family
CXX11_RS07080	COG2951	lytic endotransglycosylase activity
CXX11_RS07085	COG3730	PTS system glucitol sorbitol-specific
CXX11_RS07090	COG3732	PTS system glucitol sorbitol-specific
CXX11_RS07100	COG1028	Short-chain dehydrogenase reductase Sdr
CXX11_RS07105	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX11_RS07110	COG1349	DNA-binding transcription factor activity
CXX11_RS07115	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CXX11_RS07115	COG0517	IMP dehydrogenase activity
CXX11_RS07135	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CXX11_RS07140	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CXX11_RS07145	COG1609	Transcriptional regulator
CXX11_RS07150	COG1263	PTS System
CXX11_RS07150	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXX11_RS07155	COG2723	6-phospho-beta-galactosidase activity
CXX11_RS07160	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CXX11_RS07170	COG3260	NADH ubiquinone oxidoreductase 20
CXX11_RS07175	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CXX11_RS07180	COG3261	NADH dehydrogenase
CXX11_RS07180	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CXX11_RS07185	COG0650	Formate hydrogenlyase subunit 4
CXX11_RS07190	COG0651	ATP synthesis coupled electron transport
CXX11_RS07195	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CXX11_RS07210	COG0375	protein maturation
CXX11_RS07215	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CXX11_RS07220	COG0298	carbon dioxide binding
CXX11_RS07225	COG0409	Hydrogenase expression formation protein
CXX11_RS07230	COG0309	Hydrogenase expression formation protein (HypE)
CXX11_RS07235	COG3604	Transcriptional regulator
CXX11_RS07255	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CXX11_RS07260	COG1349	DNA-binding transcription factor activity
CXX11_RS07265	COG2084	Dehydrogenase
CXX11_RS07270	COG3395	kinase activity
CXX11_RS07275	COG0235	Class ii aldolase
CXX11_RS07295	COG3622	Belongs to the hyi family
CXX11_RS07300	COG2610	gluconate transmembrane transporter activity
CXX11_RS07305	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CXX11_RS07310	COG1388	LysM domain
CXX11_RS07310	COG4942	peptidase
CXX11_RS07365	COG2234	aminopeptidase activity
CXX11_RS07370	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CXX11_RS07375	COG1518	maintenance of DNA repeat elements
CXX11_RS07425	COG0720	synthase
CXX11_RS07430	COG0644	oxidoreductase
CXX11_RS07435	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CXX11_RS07440	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CXX11_RS07445	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CXX11_RS07455	COG0477	Major facilitator Superfamily
CXX11_RS07460	COG0277	FAD linked oxidase domain protein
CXX11_RS07465	COG1028	Short-chain dehydrogenase reductase Sdr
CXX11_RS07475	COG0602	queuosine metabolic process
CXX11_RS07510	COG3956	TIGRFAM MazG family protein
CXX11_RS07515	COG2337	Toxic component of a toxin-antitoxin (TA) module
CXX11_RS07520	COG2336	PFAM SpoVT AbrB
CXX11_RS07525	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CXX11_RS07530	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CXX11_RS07535	COG3437	response regulator, receiver
CXX11_RS07535	COG2205	protein histidine kinase activity
CXX11_RS07535	COG3850	Histidine kinase
CXX11_RS07535	COG4999	Histidine kinase
CXX11_RS07540	COG4948	Mandelate Racemase Muconate Lactonizing
CXX11_RS07545	COG4948	Mandelate Racemase Muconate Lactonizing
CXX11_RS07550	COG2271	Major facilitator Superfamily
CXX11_RS07555	COG0716	FMN binding
CXX11_RS07560	COG0564	pseudouridine synthase activity
CXX11_RS07565	COG3098	single-species biofilm formation
CXX11_RS07580	COG1611	Belongs to the LOG family
CXX11_RS07585	COG0814	amino acid
CXX11_RS07590	COG1760	l-serine dehydratase
CXX11_RS07600	COG1454	alcohol dehydrogenase
CXX11_RS07605	COG0235	Class ii aldolase
CXX11_RS07615	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CXX11_RS07620	COG1609	Transcriptional regulator
CXX11_RS07625	COG1172	Belongs to the binding-protein-dependent transport system permease family
CXX11_RS07640	COG1070	Carbohydrate kinase
CXX11_RS07650	COG1349	DNA-binding transcription factor activity
CXX11_RS07680	COG2363	Small membrane protein
CXX11_RS07685	COG0583	DNA-binding transcription factor activity
CXX11_RS07695	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CXX11_RS07700	COG2166	iron-sulfur cluster assembly
CXX11_RS07705	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CXX11_RS07710	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CXX11_RS07730	COG0860	N-Acetylmuramoyl-L-alanine amidase
CXX11_RS07735	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CXX11_RS07735	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CXX11_RS07740	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CXX11_RS07745	COG1074	ATP-dependent DNA helicase activity
CXX11_RS07750	COG1025	Belongs to the peptidase M16 family
CXX11_RS07755	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CXX11_RS07760	COG4967	type IV pilus modification protein PilV
CXX11_RS07770	COG4795	General secretion pathway protein
CXX11_RS07775	COG2165	general secretion pathway protein
CXX11_RS07795	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
CXX11_RS07815	COG0861	Integral membrane protein TerC family
CXX11_RS07825	COG0667	Aldo Keto reductase
CXX11_RS07840	COG1609	Transcriptional regulator
CXX11_RS07850	COG0583	DNA-binding transcription factor activity
CXX11_RS07855	COG1794	racemase activity, acting on amino acids and derivatives
CXX11_RS07860	COG2814	Major facilitator Superfamily
CXX11_RS07865	COG1028	Short-chain dehydrogenase reductase Sdr
CXX11_RS07875	COG0183	Belongs to the thiolase family
CXX11_RS07880	COG0814	amino acid
CXX11_RS07895	COG4942	peptidase
CXX11_RS07900	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CXX11_RS07905	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CXX11_RS07910	COG2080	2 iron, 2 sulfur cluster binding
CXX11_RS07960	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CXX11_RS07970	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CXX11_RS07975	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CXX11_RS07980	COG4974	Belongs to the 'phage' integrase family
CXX11_RS07985	COG0716	FMN binding
CXX11_RS07995	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CXX11_RS08005	COG1272	protein, Hemolysin III
CXX11_RS08015	COG2723	6-phospho-beta-galactosidase activity
CXX11_RS08020	COG1028	Short-chain dehydrogenase reductase Sdr
CXX11_RS08045	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CXX11_RS08050	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CXX11_RS08055	COG0006	proline dipeptidase activity
CXX11_RS08075	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CXX11_RS08085	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CXX11_RS08105	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CXX11_RS08105	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CXX11_RS08110	COG1703	isobutyryl-CoA mutase activity
CXX11_RS08115	COG1024	Enoyl-CoA hydratase
CXX11_RS08120	COG0427	acetyl-CoA hydrolase
CXX11_RS08125	COG0583	DNA-binding transcription factor activity
CXX11_RS08130	COG2968	Membrane
CXX11_RS08135	COG1279	arginine transmembrane transporter activity
CXX11_RS08140	COG0668	transmembrane transport
CXX11_RS08145	COG0191	fructose-bisphosphate aldolase activity
CXX11_RS08160	COG1072	(Pantothenic acid kinase))
CXX11_RS08165	COG3722	fumarate hydratase activity
CXX11_RS08170	COG1494	fructose-1,6-bisphosphatase
CXX11_RS08175	COG1063	alcohol dehydrogenase
CXX11_RS08180	COG2213	PTS system mannitol-specific
CXX11_RS08185	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX11_RS08190	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CXX11_RS08195	COG0501	Belongs to the peptidase M48B family
CXX11_RS08205	COG1166	arginine decarboxylase activity
CXX11_RS08230	COG2814	Major facilitator Superfamily
CXX11_RS08240	COG2356	endonuclease I
CXX11_RS08245	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CXX11_RS08250	COG0189	ligase activity
CXX11_RS08265	COG2805	Type II/IV secretion system protein
CXX11_RS08270	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CXX11_RS08275	COG0762	integral membrane protein
CXX11_RS08285	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CXX11_RS08290	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CXX11_RS08300	COG0252	asparaginase activity
CXX11_RS08310	COG3171	Protein conserved in bacteria
CXX11_RS08320	COG1194	a g-specific adenine glycosylase
CXX11_RS08335	COG2211	Major facilitator Superfamily
CXX11_RS08340	COG1982	Orn Lys Arg decarboxylase major
CXX11_RS08345	COG1811	Na channel or pump
CXX11_RS08355	COG0582	viral genome integration into host DNA
CXX11_RS08385	COG3727	T/G mismatch-specific endonuclease activity
CXX11_RS08455	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CXX11_RS08480	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CXX11_RS08510	COG2165	general secretion pathway protein
CXX11_RS08515	COG1459	type II secretion system
CXX11_RS08520	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CXX11_RS08540	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CXX11_RS08550	COG1620	l-lactate permease
CXX11_RS08555	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CXX11_RS08560	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CXX11_RS08565	COG0247	lactate metabolic process
CXX11_RS08570	COG0277	FAD linked oxidase domain protein
CXX11_RS08575	COG0277	FAD linked oxidase domain protein
CXX11_RS08580	COG2186	Transcriptional regulator
CXX11_RS08585	COG0456	acetyltransferase
CXX11_RS08590	COG0318	PFAM AMP-dependent synthetase and ligase
CXX11_RS08600	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CXX11_RS08605	COG0156	8-amino-7-oxononanoate synthase activity
CXX11_RS08615	COG0795	lipopolysaccharide-transporting ATPase activity
CXX11_RS08620	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CXX11_RS08630	COG2244	polysaccharide biosynthetic process
CXX11_RS08635	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CXX11_RS08645	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CXX11_RS08650	COG0306	phosphate transporter
CXX11_RS08655	COG0754	glutathionylspermidine amidase activity
CXX11_RS08660	COG0625	glutathione transferase activity
CXX11_RS08665	COG0298	carbon dioxide binding
CXX11_RS08675	COG1773	rubredoxin
CXX11_RS08680	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CXX11_RS08685	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CXX11_RS08690	COG5557	Pfam Polysulphide reductase, NrfD
CXX11_RS08695	COG0437	4 iron, 4 sulfur cluster binding
CXX11_RS08700	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CXX11_RS08715	COG0667	Aldo Keto reductase
CXX11_RS08725	COG1028	Short-chain dehydrogenase reductase Sdr
CXX11_RS08730	COG0848	biopolymer transport protein
CXX11_RS08735	COG0811	peptide transport
CXX11_RS08740	COG0626	cystathionine gamma-synthase activity
CXX11_RS08745	COG0586	Pfam SNARE associated Golgi protein
CXX11_RS08750	COG2207	Transcriptional regulator
CXX11_RS08755	COG1979	alcohol dehydrogenase
CXX11_RS08760	COG0656	L-ascorbic acid biosynthetic process
CXX11_RS08780	COG4238	major outer membrane lipoprotein
CXX11_RS08785	COG1032	radical SAM domain protein
CXX11_RS08790	COG2132	Multicopper oxidase
CXX11_RS08795	COG0204	Acyl-transferase
CXX11_RS08800	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CXX11_RS08805	COG4166	transmembrane transport
CXX11_RS08810	COG2944	sequence-specific DNA binding
CXX11_RS08820	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CXX11_RS08825	COG3111	PFAM Bacterial OB fold (BOF) protein
CXX11_RS08830	COG0745	RESPONSE REGULATOR receiver
CXX11_RS08835	COG0642	Histidine kinase
CXX11_RS08845	COG2249	NAD(P)H dehydrogenase (quinone) activity
CXX11_RS08850	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CXX11_RS08855	COG0187	DNA topoisomerase II activity
CXX11_RS08860	COG3150	esterase
CXX11_RS08865	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CXX11_RS08870	COG3151	Protein conserved in bacteria
CXX11_RS08875	COG0494	nUDIX hydrolase
CXX11_RS08880	COG1538	Outer membrane efflux protein
CXX11_RS08890	COG0754	glutathionylspermidine amidase activity
CXX11_RS08895	COG3384	dioxygenase
CXX11_RS08915	COG2960	long-chain fatty acid transporting porin activity
CXX11_RS08920	COG3539	Fimbrial protein
CXX11_RS08940	COG3121	Chaperone
CXX11_RS08945	COG3539	Fimbrial protein
CXX11_RS08955	COG1585	Membrane protein implicated in regulation of membrane protease activity
CXX11_RS08960	COG2268	Band 7 protein
CXX11_RS08985	COG3025	triphosphatase activity
CXX11_RS08990	COG4991	sh3 domain protein
CXX11_RS09005	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CXX11_RS09015	COG0583	DNA-binding transcription factor activity
CXX11_RS09020	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CXX11_RS09025	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CXX11_RS09030	COG0471	metal ion transport
CXX11_RS09040	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CXX11_RS09045	COG0358	DNA primase activity
CXX11_RS09050	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CXX11_RS09065	COG2375	cellular response to nickel ion
CXX11_RS09070	COG1695	Transcriptional regulator
CXX11_RS09075	COG0840	transmembrane signaling receptor activity
CXX11_RS09085	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CXX11_RS09090	COG1609	Transcriptional regulator
CXX11_RS09095	COG3250	beta-galactosidase activity
CXX11_RS09100	COG2731	YhcH YjgK YiaL family protein
CXX11_RS09105	COG0531	amino acid
CXX11_RS09115	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
CXX11_RS09115	COG3408	Glycogen debranching enzyme
CXX11_RS09120	COG1902	pentaerythritol trinitrate reductase activity
CXX11_RS09120	COG0446	pyridine nucleotide-disulphide oxidoreductase
CXX11_RS09125	COG5499	transcription regulator containing HTH domain
CXX11_RS09130	COG4680	protein conserved in bacteria
CXX11_RS09140	COG1451	nucleotide metabolic process
CXX11_RS09145	COG2949	membrane
CXX11_RS09150	COG0673	inositol 2-dehydrogenase activity
CXX11_RS09155	COG0861	Integral membrane protein TerC family
CXX11_RS09160	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CXX11_RS09170	COG2721	sulfolactate sulfo-lyase activity
CXX11_RS09180	COG2271	Major facilitator Superfamily
CXX11_RS09210	COG2186	Transcriptional regulator
CXX11_RS09215	COG0586	Pfam SNARE associated Golgi protein
CXX11_RS09225	COG1422	Protein of unknown function (DUF1090)
CXX11_RS09230	COG4575	ribosome binding
CXX11_RS09235	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CXX11_RS09245	COG2259	Doxx family
CXX11_RS09255	COG3152	Membrane
CXX11_RS09260	COG3152	Membrane
CXX11_RS09265	COG0583	DNA-binding transcription factor activity
CXX11_RS09270	COG1741	Belongs to the pirin family
CXX11_RS09285	COG0814	amino acid
CXX11_RS09290	COG1760	l-serine dehydratase
CXX11_RS09295	COG0251	oxidation-reduction process
CXX11_RS09310	COG0583	DNA-binding transcription factor activity
CXX11_RS09335	COG1929	Belongs to the glycerate kinase type-1 family
CXX11_RS09340	COG2084	Dehydrogenase
CXX11_RS09350	COG2271	Major facilitator Superfamily
CXX11_RS09355	COG2721	sulfolactate sulfo-lyase activity
CXX11_RS09360	COG2002	toxin-antitoxin pair type II binding
CXX11_RS09370	COG1349	DNA-binding transcription factor activity
CXX11_RS09380	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXX11_RS09390	COG3716	PTS system mannose fructose sorbose family IID component
CXX11_RS09395	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX11_RS09400	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CXX11_RS09405	COG2222	sugar isomerase
CXX11_RS09415	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXX11_RS09420	COG3715	PTS system
CXX11_RS09425	COG3716	PTS system mannose fructose sorbose family IID component
CXX11_RS09430	COG0363	glucosamine-6-phosphate deaminase activity
CXX11_RS09435	COG3539	Fimbrial protein
CXX11_RS09440	COG3121	Chaperone
CXX11_RS09445	COG3188	usher protein
CXX11_RS09450	COG3539	Fimbrial protein
CXX11_RS09455	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CXX11_RS09460	COG3107	peptidoglycan biosynthetic process
CXX11_RS09475	COG2823	Periplasmic or secreted lipoprotein
CXX11_RS09480	COG0701	Predicted permease
CXX11_RS09485	COG0702	epimerase
CXX11_RS09490	COG0693	protein deglycase activity
CXX11_RS09505	COG3153	acetyltransferase
CXX11_RS09510	COG3154	lipid carrier protein
CXX11_RS09515	COG0826	peptidase U32
CXX11_RS09520	COG0826	peptidase U32
CXX11_RS09525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CXX11_RS09530	COG0814	amino acid
CXX11_RS09535	COG0513	Belongs to the DEAD box helicase family
CXX11_RS09575	COG0195	Participates in both transcription termination and antitermination
CXX11_RS09595	COG2194	sulfuric ester hydrolase activity
CXX11_RS09605	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CXX11_RS09615	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CXX11_RS09620	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CXX11_RS09630	COG1534	Rna-binding protein
CXX11_RS09635	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CXX11_RS09640	COG2027	D-alanyl-D-alanine carboxypeptidase
CXX11_RS09650	COG0697	spore germination
CXX11_RS09665	COG0142	geranyltranstransferase activity
CXX11_RS09670	COG3423	Transcriptional regulator
CXX11_RS09680	COG5007	Belongs to the BolA IbaG family
CXX11_RS09685	COG3113	response to antibiotic
CXX11_RS09690	COG2854	intermembrane phospholipid transfer
CXX11_RS09695	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CXX11_RS09700	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CXX11_RS09705	COG1127	ABC transporter
CXX11_RS09710	COG0530	calcium, potassium:sodium antiporter activity
CXX11_RS09715	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CXX11_RS09715	COG0517	IMP dehydrogenase activity
CXX11_RS09720	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CXX11_RS09725	COG3117	lipopolysaccharide transmembrane transporter activity
CXX11_RS09730	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CXX11_RS09735	COG1137	ATPase activity
CXX11_RS09740	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CXX11_RS09745	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CXX11_RS09760	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX11_RS09785	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CXX11_RS09790	COG0784	Response regulator, receiver
CXX11_RS09790	COG5002	protein histidine kinase activity
CXX11_RS09790	COG2198	Histidine kinase
CXX11_RS09795	COG1242	4 iron, 4 sulfur cluster binding
CXX11_RS09800	COG0069	glutamate synthase activity
CXX11_RS09800	COG0070	glutamate synthase
CXX11_RS09800	COG0067	glutamate synthase
CXX11_RS09805	COG0493	'glutamate synthase
CXX11_RS09820	COG4804	nuclease activity
CXX11_RS09830	COG2731	YhcH YjgK YiaL family protein
CXX11_RS09860	COG3069	C4-dicarboxylate transmembrane transporter activity
CXX11_RS09865	COG2969	positive regulation of protein catabolic process
CXX11_RS09870	COG0625	glutathione transferase activity
CXX11_RS09890	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CXX11_RS09895	COG3105	Protein conserved in bacteria
CXX11_RS09900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CXX11_RS09905	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CXX11_RS09925	COG2732	(Barnase) inhibitor
CXX11_RS09945	COG0583	DNA-binding transcription factor activity
CXX11_RS09950	COG0312	modulator of DNA gyrase
CXX11_RS09955	COG3164	Protein of unknown function
CXX11_RS09960	COG1530	ribonuclease E activity
CXX11_RS09970	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CXX11_RS09975	COG1792	Involved in formation and maintenance of cell shape
CXX11_RS09980	COG1077	Cell shape determining protein MreB Mrl
CXX11_RS09990	COG2200	EAL domain
CXX11_RS09990	COG2199	diguanylate cyclase activity
CXX11_RS09995	COG0604	alcohol dehydrogenase
CXX11_RS10005	COG0511	ligase activity, forming carbon-carbon bonds
CXX11_RS10010	COG0439	Biotin carboxylase
CXX11_RS10015	COG3924	membrane
CXX11_RS10020	COG4145	pantothenate transmembrane transporter activity
CXX11_RS10030	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CXX11_RS10040	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CXX11_RS10050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CXX11_RS10055	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CXX11_RS10065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXX11_RS10070	COG4597	amino acid ABC transporter
CXX11_RS10075	COG0765	amino acid transport
CXX11_RS10080	COG1126	abc transporter atp-binding protein
CXX11_RS10135	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CXX11_RS10155	COG0551	DNA topoisomerase type I activity
CXX11_RS10165	COG0758	DNA mediated transformation
CXX11_RS10185	COG0569	domain protein
CXX11_RS10195	COG3036	rescue of stalled ribosome
CXX11_RS10200	COG0789	Transcriptional regulator
CXX11_RS10240	COG0201	protein transport
CXX11_RS10330	COG0089	rRNA binding
CXX11_RS10400	COG2964	Protein conserved in bacteria
CXX11_RS10405	COG0545	Peptidyl-prolyl cis-trans isomerase
CXX11_RS10415	COG1047	Peptidyl-prolyl cis-trans
CXX11_RS10420	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CXX11_RS10435	COG0488	(ABC) transporter
CXX11_RS10440	COG0429	hydrolase of the alpha beta-hydrolase fold
CXX11_RS10450	COG3954	Phosphoribulokinase
CXX11_RS10455	COG1765	OsmC-like protein
CXX11_RS10460	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CXX11_RS10465	COG1289	transmembrane transporter activity
CXX11_RS10470	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CXX11_RS10475	COG0512	Glutamine amidotransferase of anthranilate synthase
CXX11_RS10480	COG2184	nucleotidyltransferase activity
CXX11_RS10490	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CXX11_RS10500	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CXX11_RS10505	COG2146	nitrite reductase [NAD(P)H] activity
CXX11_RS10510	COG2116	formate transmembrane transporter activity
CXX11_RS10525	COG0531	amino acid
CXX11_RS10530	COG2222	sugar isomerase
CXX11_RS10550	COG1278	Cold shock
CXX11_RS10555	COG2944	sequence-specific DNA binding
CXX11_RS10570	COG2885	chlorophyll binding
CXX11_RS10575	COG0243	molybdopterin cofactor binding
CXX11_RS10580	COG0456	acetyltransferase
CXX11_RS10585	COG2818	Glycosylase
CXX11_RS10590	COG5571	outer membrane autotransporter
CXX11_RS10595	COG2223	nitrite transmembrane transporter activity
CXX11_RS10600	COG2194	sulfuric ester hydrolase activity
CXX11_RS10610	COG0747	negative chemotaxis
CXX11_RS10620	COG0601	transmembrane transport
CXX11_RS10625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CXX11_RS10630	COG0444	Belongs to the ABC transporter superfamily
CXX11_RS10635	COG4608	Belongs to the ABC transporter superfamily
CXX11_RS10640	COG0814	amino acid
CXX11_RS10695	COG1215	transferase activity, transferring glycosyl groups
CXX11_RS10700	COG1215	transferase activity, transferring glycosyl groups
CXX11_RS10705	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CXX11_RS10725	COG2200	EAL domain
CXX11_RS10725	COG2199	diguanylate cyclase activity
CXX11_RS10735	COG0612	Peptidase, M16
CXX11_RS10745	COG2200	EAL domain
CXX11_RS10750	COG2982	Protein involved in outer membrane biogenesis
CXX11_RS10755	COG0477	Major facilitator Superfamily
CXX11_RS10760	COG1295	ribonuclease BN
CXX11_RS10765	COG0583	DNA-binding transcription factor activity
CXX11_RS10770	COG2197	response regulator
CXX11_RS10780	COG1858	cytochrome C peroxidase
CXX11_RS10785	COG0076	glutamate decarboxylase activity
CXX11_RS10790	COG2207	Transcriptional regulator
CXX11_RS10795	COG2207	Transcriptional regulator
CXX11_RS10800	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CXX11_RS10805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CXX11_RS10815	COG2771	luxR family
CXX11_RS10820	COG3247	response to pH
CXX11_RS10835	COG1285	pathogenesis
CXX11_RS10840	COG2197	response regulator
CXX11_RS10845	COG3065	identical protein binding
CXX11_RS10855	COG1393	Belongs to the ArsC family
CXX11_RS10860	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CXX11_RS10865	COG0640	Transcriptional regulator
CXX11_RS10875	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CXX11_RS10880	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CXX11_RS10885	COG0339	signal peptide processing
CXX11_RS10895	COG3104	oligopeptide transport
CXX11_RS10900	COG0589	response to stress
CXX11_RS10910	COG0306	phosphate transporter
CXX11_RS10915	COG2081	HI0933 family
CXX11_RS10935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CXX11_RS10940	COG1129	ABC transporter
CXX11_RS10940	COG0842	Transport permease protein
CXX11_RS10945	COG0842	Transport permease protein
CXX11_RS10950	COG5433	transposase activity
CXX11_RS10955	COG1413	lyase activity
CXX11_RS10965	COG3209	COG3209 Rhs family protein
CXX11_RS10985	COG0444	Belongs to the ABC transporter superfamily
CXX11_RS10990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CXX11_RS10995	COG0601	transmembrane transport
CXX11_RS11000	COG0747	negative chemotaxis
CXX11_RS11005	COG2091	lysine biosynthetic process via aminoadipic acid
CXX11_RS11010	COG0628	permease
CXX11_RS11015	COG0477	Major facilitator Superfamily
CXX11_RS11025	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CXX11_RS11040	COG3714	YhhN family
CXX11_RS11050	COG3776	membrane
CXX11_RS11055	COG0742	ribosomal rna small subunit methyltransferase
CXX11_RS11060	COG0552	protein localization to endoplasmic reticulum
CXX11_RS11065	COG2884	Cell division ATP-binding protein ftsE
CXX11_RS11070	COG2177	Part of the ABC transporter FtsEX involved in
CXX11_RS11075	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CXX11_RS11080	COG0683	leucine binding
CXX11_RS11085	COG0456	acetyltransferase
CXX11_RS11090	COG0683	leucine binding
CXX11_RS11095	COG0559	Belongs to the binding-protein-dependent transport system permease family
CXX11_RS11100	COG4177	L-phenylalanine transmembrane transporter activity
CXX11_RS11105	COG0411	ABC transporter
CXX11_RS11110	COG0410	ABC transporter
CXX11_RS11115	COG1653	transport
CXX11_RS11120	COG1175	transmembrane transport
CXX11_RS11130	COG3842	ATPase activity
CXX11_RS11135	COG0584	glycerophosphoryl diester phosphodiesterase
CXX11_RS11145	COG0405	Gamma-glutamyltransferase
CXX11_RS11170	COG3157	Type VI secretion system effector, Hcp
CXX11_RS11175	COG1247	-acetyltransferase
CXX11_RS11180	COG0673	inositol 2-dehydrogenase activity
CXX11_RS11185	COG1741	Belongs to the pirin family
CXX11_RS11190	COG1609	Transcriptional regulator
CXX11_RS11195	COG3265	gluconokinase activity
CXX11_RS11200	COG2610	gluconate transmembrane transporter activity
CXX11_RS11205	COG2095	MarC family integral membrane protein
CXX11_RS11210	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CXX11_RS11235	COG0058	SHG alpha-glucan phosphorylase activity
CXX11_RS11240	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CXX11_RS11260	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CXX11_RS11275	COG1349	DNA-binding transcription factor activity
CXX11_RS11280	COG4650	regulator
CXX11_RS11285	COG1690	Belongs to the RtcB family
CXX11_RS11300	COG0058	SHG alpha-glucan phosphorylase activity
CXX11_RS11305	COG1640	4-alpha-glucanotransferase
CXX11_RS11310	COG2610	gluconate transmembrane transporter activity
CXX11_RS11320	COG1040	competence protein
CXX11_RS11330	COG5464	transposase or invertase
CXX11_RS11340	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CXX11_RS11345	COG1918	ferrous iron import across plasma membrane
CXX11_RS11350	COG2183	response to ionizing radiation
CXX11_RS11355	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CXX11_RS11375	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CXX11_RS11385	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CXX11_RS11390	COG1011	Hydrolase
CXX11_RS11400	COG0494	nUDIX hydrolase
CXX11_RS11405	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CXX11_RS11410	COG4972	Pilus assembly protein
CXX11_RS11415	COG3166	PFAM Fimbrial assembly family protein
CXX11_RS11430	COG4796	Type ii and iii secretion system protein
CXX11_RS11445	COG3266	domain, Protein
CXX11_RS11450	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CXX11_RS11455	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CXX11_RS11460	COG0546	phosphoglycolate phosphatase activity
CXX11_RS11465	COG0180	Tryptophanyl-tRNA synthetase
CXX11_RS11475	COG2188	Transcriptional regulator
CXX11_RS11485	COG3457	Alanine racemase
CXX11_RS11490	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CXX11_RS11495	COG1735	metal-dependent hydrolase with the TIM-barrel fold
CXX11_RS11510	COG0626	cystathionine gamma-synthase activity
CXX11_RS11515	COG2188	Transcriptional regulator
CXX11_RS11520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CXX11_RS11550	COG3274	enterobacterial common antigen metabolic process
CXX11_RS11555	COG4682	membrane
CXX11_RS11560	COG4682	membrane
CXX11_RS11575	COG1129	ABC transporter
CXX11_RS11580	COG4214	carbohydrate transport
CXX11_RS11585	COG2207	Transcriptional regulator
CXX11_RS11585	COG1609	Transcriptional regulator
CXX11_RS11590	COG2992	FlgJ-related protein
CXX11_RS11595	COG0366	Alpha amylase catalytic
CXX11_RS11600	COG3977	Valine--pyruvate aminotransferase
CXX11_RS11605	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CXX11_RS11610	COG1414	Transcriptional regulator
CXX11_RS11620	COG2731	YhcH YjgK YiaL family protein
CXX11_RS11625	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CXX11_RS11630	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CXX11_RS11635	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CXX11_RS11640	COG1070	Carbohydrate kinase
CXX11_RS11645	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CXX11_RS11650	COG3623	hexulose-6-phosphate isomerase
CXX11_RS11655	COG0235	Class ii aldolase
CXX11_RS11665	COG2211	Major facilitator Superfamily
CXX11_RS11675	COG3713	MltA-interacting MipA family protein
CXX11_RS11680	COG0583	DNA-binding transcription factor activity
CXX11_RS11685	COG1566	PFAM secretion protein HlyD family protein
CXX11_RS11695	COG1566	PFAM secretion protein HlyD family protein
CXX11_RS11710	COG1012	belongs to the aldehyde dehydrogenase family
CXX11_RS11720	COG3276	selenocysteine insertion sequence binding
CXX11_RS11730	COG0625	glutathione transferase activity
CXX11_RS11735	COG3209	COG3209 Rhs family protein
CXX11_RS11740	COG1413	lyase activity
CXX11_RS11750	COG3209	COG3209 Rhs family protein
CXX11_RS11755	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CXX11_RS11775	COG1566	PFAM secretion protein HlyD family protein
CXX11_RS11785	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX11_RS11785	COG2213	PTS system mannitol-specific
CXX11_RS11795	COG3722	fumarate hydratase activity
CXX11_RS11820	COG5295	Hep Hag repeat protein
CXX11_RS11825	COG1620	l-lactate permease
CXX11_RS11830	COG2186	Transcriptional regulator
CXX11_RS11840	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CXX11_RS11845	COG1045	serine acetyltransferase
CXX11_RS11860	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CXX11_RS11865	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CXX11_RS11880	COG4942	peptidase
CXX11_RS11885	COG2861	carbohydrate metabolic process
CXX11_RS11890	COG1216	Glycosyl transferase, family 2
CXX11_RS11900	COG0156	8-amino-7-oxononanoate synthase activity
CXX11_RS11910	COG0859	PFAM glycosyl transferase family 9
CXX11_RS11915	COG0859	PFAM glycosyl transferase family 9
CXX11_RS11920	COG3307	-O-antigen
CXX11_RS11925	COG1216	Glycosyl transferase, family 2
CXX11_RS11930	COG1442	glycosyl transferase family 8
CXX11_RS11935	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CXX11_RS11950	COG0515	serine threonine protein kinase
CXX11_RS11955	COG0438	transferase activity, transferring glycosyl groups
CXX11_RS11960	COG0859	PFAM glycosyl transferase family 9
CXX11_RS11965	COG1519	Transferase
CXX11_RS11995	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CXX11_RS12020	COG1561	YicC-like family, N-terminal region
CXX11_RS12025	COG3645	SOS response
CXX11_RS12030	COG2860	membrane
CXX11_RS12040	COG0194	GDP metabolic process
CXX11_RS12050	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CXX11_RS12055	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CXX11_RS12060	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CXX11_RS12070	COG0786	glutamate:sodium symporter activity
CXX11_RS12075	COG2233	PERMEase
CXX11_RS12080	COG2982	Protein involved in outer membrane biogenesis
CXX11_RS12095	COG1501	Belongs to the glycosyl hydrolase 31 family
CXX11_RS12100	COG2211	Major facilitator Superfamily
CXX11_RS12110	COG0582	viral genome integration into host DNA
CXX11_RS12130	COG2271	Major facilitator Superfamily
CXX11_RS12145	COG1484	DNA-dependent DNA replication
CXX11_RS12150	COG4584	PFAM Integrase catalytic
CXX11_RS12160	COG4372	Transposase
CXX11_RS12165	COG3436	PFAM IS66 Orf2 family protein
CXX11_RS12205	COG2223	nitrite transmembrane transporter activity
CXX11_RS12225	COG1401	restriction endodeoxyribonuclease activity
CXX11_RS12285	COG4983	Phage plasmid primase, P4 family domain protein
CXX11_RS12310	COG2252	PERMEase
CXX11_RS12320	COG2271	Major facilitator Superfamily
CXX11_RS12325	COG2271	Major facilitator Superfamily
CXX11_RS12330	COG3851	Histidine kinase
CXX11_RS12335	COG2197	response regulator
CXX11_RS12340	COG0440	acetolactate synthase activity
CXX11_RS12345	COG0028	Belongs to the TPP enzyme family
CXX11_RS12365	COG2814	Major facilitator Superfamily
CXX11_RS12370	COG0641	radical SAM
CXX11_RS12380	COG2149	membrane
CXX11_RS12400	COG3119	arylsulfatase activity
CXX11_RS12405	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CXX11_RS12445	COG5645	(Lipo)protein
CXX11_RS12450	COG0823	Involved in the tonB-independent uptake of proteins
CXX11_RS12460	COG2271	Major facilitator Superfamily
CXX11_RS12470	COG0800	Aldolase
CXX11_RS12475	COG3734	2-keto-3-deoxy-galactonokinase
CXX11_RS12480	COG2186	Transcriptional regulator
CXX11_RS12490	COG0561	phosphatase activity
CXX11_RS12495	COG3753	Protein conserved in bacteria
CXX11_RS12500	COG0187	DNA topoisomerase II activity
CXX11_RS12510	COG0592	DNA-directed DNA polymerase activity
CXX11_RS12560	COG0814	amino acid
CXX11_RS12575	COG2091	lysine biosynthetic process via aminoadipic acid
CXX11_RS12580	COG0431	NADPH-dependent FMN reductase
CXX11_RS12585	COG2252	PERMEase
CXX11_RS12590	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CXX11_RS12600	COG3196	Protein conserved in bacteria
CXX11_RS12615	COG0363	glucosamine-6-phosphate deaminase activity
CXX11_RS12620	COG2382	esterase
CXX11_RS12630	COG2723	6-phospho-beta-galactosidase activity
CXX11_RS12635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXX11_RS12635	COG2190	(PTS) system
CXX11_RS12635	COG1263	PTS System
CXX11_RS12640	COG3711	transcriptional antiterminator
CXX11_RS12655	COG0704	Plays a role in the regulation of phosphate uptake
CXX11_RS12660	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CXX11_RS12665	COG0581	inorganic phosphate transmembrane transporter activity
CXX11_RS12670	COG0573	inorganic phosphate transmembrane transporter activity
CXX11_RS12675	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CXX11_RS12680	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CXX11_RS12730	COG3312	ion transport
CXX11_RS12745	COG0716	FMN binding
CXX11_RS12750	COG1522	sequence-specific DNA binding
CXX11_RS12775	COG1869	D-ribose catabolic process
CXX11_RS12780	COG1129	ABC transporter
CXX11_RS12785	COG1172	Belongs to the binding-protein-dependent transport system permease family
CXX11_RS12790	COG1879	ABC-type sugar transport system periplasmic component
CXX11_RS12795	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CXX11_RS12800	COG1609	Transcriptional regulator
CXX11_RS12805	COG0477	Major facilitator Superfamily
CXX11_RS12810	COG2186	Transcriptional regulator
CXX11_RS12850	COG3085	chromosome segregation
CXX11_RS12855	COG0606	chelatase, subunit chli
CXX11_RS12875	COG3978	acetolactate synthase activity
CXX11_RS12880	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CXX11_RS12890	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CXX11_RS12895	COG0583	DNA-binding transcription factor activity
CXX11_RS12905	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CXX11_RS12915	COG0210	DNA helicase
CXX11_RS12930	COG3118	belongs to the thioredoxin family
CXX11_RS12940	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CXX11_RS12945	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CXX11_RS12950	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CXX11_RS12970	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CXX11_RS12975	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CXX11_RS12980	COG1088	dTDP-glucose 4,6-dehydratase activity
CXX11_RS12985	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CXX11_RS12990	COG0456	acetyltransferase
CXX11_RS12995	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CXX11_RS13000	COG2244	polysaccharide biosynthetic process
CXX11_RS13020	COG1113	amino acid transport
CXX11_RS13045	COG0641	radical SAM
CXX11_RS13055	COG3071	HemY protein
CXX11_RS13060	COG2959	enzyme of heme biosynthesis
CXX11_RS13065	COG1587	Uroporphyrinogen-III synthase
CXX11_RS13075	COG3072	Adenylate cyclase
CXX11_RS13090	COG5567	small periplasmic lipoprotein
CXX11_RS13100	COG3159	Protein conserved in bacteria
CXX11_RS13110	COG1011	Hydrolase
CXX11_RS13115	COG0210	DNA helicase
CXX11_RS13120	COG3698	Phosphodiester glycosidase
CXX11_RS13125	COG0598	Magnesium transport protein CorA
CXX11_RS13155	COG2962	Rard protein
CXX11_RS13160	COG2050	protein possibly involved in aromatic compounds catabolism
CXX11_RS13165	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
CXX11_RS13170	COG0514	ATP-dependent DNA helicase (RecQ)
CXX11_RS13175	COG1280	lysine exporter protein (LysE YggA)
CXX11_RS13180	COG1280	lysine exporter protein (LysE YggA)
CXX11_RS13185	COG2267	carboxylic ester hydrolase activity
CXX11_RS13190	COG0561	phosphatase activity
CXX11_RS13195	COG0697	spore germination
CXX11_RS13200	COG0583	DNA-binding transcription factor activity
CXX11_RS13210	COG0412	Dienelactone hydrolase
CXX11_RS13215	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CXX11_RS13220	COG1322	Protein conserved in bacteria
CXX11_RS13230	COG3165	ubiquinone biosynthetic process from chorismate
CXX11_RS13240	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CXX11_RS13245	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CXX11_RS13250	COG0805	protein transport
CXX11_RS13255	COG0084	hydrolase, TatD family'
CXX11_RS13260	COG0250	Participates in transcription elongation, termination and antitermination
CXX11_RS13265	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CXX11_RS13270	COG0543	2 iron, 2 sulfur cluster binding
CXX11_RS13305	COG1739	Uncharacterized protein family UPF0029
CXX11_RS13310	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CXX11_RS13315	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CXX11_RS13345	COG1763	Mo-molybdopterin cofactor biosynthetic process
CXX11_RS13350	COG0746	molybdenum cofactor guanylyltransferase activity
CXX11_RS13355	COG3084	Protein conserved in bacteria
CXX11_RS13360	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CXX11_RS13365	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CXX11_RS13370	COG5339	Protein conserved in bacteria
CXX11_RS13375	COG0204	Acyl-transferase
CXX11_RS13385	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CXX11_RS13385	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CXX11_RS13395	COG3078	GTPase activator activity
CXX11_RS13400	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CXX11_RS13410	COG2204	response regulator
CXX11_RS13415	COG3852	Histidine kinase
CXX11_RS13420	COG0174	glutamine synthetase
CXX11_RS13425	COG1217	gtp-binding protein TYPA
CXX11_RS13430	COG2188	Transcriptional regulator
CXX11_RS13445	COG2211	Major facilitator Superfamily
CXX11_RS13450	COG2211	Major facilitator Superfamily
CXX11_RS13455	COG1501	Belongs to the glycosyl hydrolase 31 family
CXX11_RS13465	COG2017	converts alpha-aldose to the beta-anomer
CXX11_RS13470	COG2942	2-epimerase
CXX11_RS13475	COG3684	Belongs to the aldolase LacD family
CXX11_RS13480	COG2084	Dehydrogenase
CXX11_RS13485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CXX11_RS13490	COG1349	DNA-binding transcription factor activity
CXX11_RS13495	COG1011	Hydrolase
CXX11_RS13510	COG0456	acetyltransferase
CXX11_RS13515	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CXX11_RS13520	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CXX11_RS13535	COG2864	formate dehydrogenase
CXX11_RS13540	COG0437	4 iron, 4 sulfur cluster binding
CXX11_RS13560	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX11_RS13560	COG3711	transcriptional antiterminator
CXX11_RS13565	COG1363	Peptidase, m42
CXX11_RS13570	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CXX11_RS13570	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CXX11_RS13610	COG1917	Cupin 2, conserved barrel domain protein
CXX11_RS13610	COG4977	sequence-specific DNA binding
CXX11_RS13620	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CXX11_RS13630	COG2258	MOSC domain
CXX11_RS13635	COG2205	protein histidine kinase activity
CXX11_RS13640	COG0745	RESPONSE REGULATOR receiver
CXX11_RS13645	COG3678	ATP-independent chaperone mediated protein folding
CXX11_RS13660	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CXX11_RS13680	COG3152	Membrane
CXX11_RS13685	COG3691	Protein conserved in bacteria
CXX11_RS13690	COG0589	response to stress
CXX11_RS13695	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CXX11_RS13700	COG1494	fructose-1,6-bisphosphatase
CXX11_RS13710	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CXX11_RS13725	COG1575	Belongs to the MenA family. Type 1 subfamily
CXX11_RS13740	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CXX11_RS13745	COG1609	Transcriptional regulator
CXX11_RS13750	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CXX11_RS13760	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
CXX11_RS13770	COG0626	cystathionine gamma-synthase activity
CXX11_RS13775	COG0527	aspartate kinase activity
CXX11_RS13775	COG0460	homoserine dehydrogenase
CXX11_RS13780	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CXX11_RS13790	COG0697	spore germination
CXX11_RS13795	COG3738	Protein conserved in bacteria
CXX11_RS13800	COG0371	Dehydrogenase
CXX11_RS13805	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CXX11_RS13810	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CXX11_RS13810	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX11_RS13810	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX11_RS13815	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CXX11_RS13820	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CXX11_RS13825	COG1882	Formate acetyltransferase
CXX11_RS13830	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CXX11_RS13835	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CXX11_RS13840	COG2207	Transcriptional regulator
CXX11_RS13845	COG2194	sulfuric ester hydrolase activity
CXX11_RS13860	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CXX11_RS13875	COG0583	DNA-binding transcription factor activity
CXX11_RS13885	COG1309	transcriptional regulator
CXX11_RS13900	COG4206	TonB-dependent receptor
CXX11_RS13935	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CXX11_RS13935	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CXX11_RS13970	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CXX11_RS13975	COG0250	Participates in transcription elongation, termination and antitermination
CXX11_RS14015	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CXX11_RS14025	COG2104	thiamine diphosphate biosynthetic process
CXX11_RS14030	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CXX11_RS14065	COG3068	Protein conserved in bacteria
CXX11_RS14080	COG3678	ATP-independent chaperone mediated protein folding
CXX11_RS14085	COG4191	Histidine kinase
CXX11_RS14090	COG2204	response regulator
CXX11_RS14095	COG0151	Belongs to the GarS family
CXX11_RS14125	COG0456	acetyltransferase
CXX11_RS14135	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CXX11_RS14140	COG2224	Isocitrate lyase
CXX11_RS14160	COG1414	Transcriptional regulator
CXX11_RS14165	COG1410	methionine synthase
CXX11_RS14165	COG0646	methionine synthase
CXX11_RS14170	COG1283	sodium-dependent phosphate transmembrane transporter activity
CXX11_RS14180	COG1187	pseudouridine synthase activity
CXX11_RS14190	COG0527	aspartate kinase activity
CXX11_RS14220	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CXX11_RS14235	COG2814	Major facilitator Superfamily
CXX11_RS14235	COG0477	Major facilitator Superfamily
CXX11_RS14240	COG3833	ABC-type maltose transport systems, permease component
CXX11_RS14245	COG1175	transmembrane transport
CXX11_RS14250	COG2182	Extracellular solute-binding protein
CXX11_RS14255	COG3842	ATPase activity
CXX11_RS14290	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CXX11_RS14300	COG0534	Mate efflux family protein
CXX11_RS14305	COG3237	CsbD-like
CXX11_RS14310	COG0735	belongs to the Fur family
CXX11_RS14325	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CXX11_RS14335	COG0604	alcohol dehydrogenase
CXX11_RS14340	COG0305	Participates in initiation and elongation during chromosome replication
CXX11_RS14345	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CXX11_RS14350	COG1448	Aminotransferase
CXX11_RS14360	COG3700	Belongs to the class B bacterial acid phosphatase family
CXX11_RS14365	COG0432	Pfam Uncharacterised protein family UPF0047
CXX11_RS14370	COG2315	Protein conserved in bacteria
CXX11_RS14375	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CXX11_RS14380	COG0629	single-stranded DNA binding
CXX11_RS14395	COG2207	Transcriptional regulator
CXX11_RS14400	COG0789	Transcriptional regulator
CXX11_RS14405	COG2252	PERMEase
CXX11_RS14410	COG0025	NhaP-type Na H and K H
CXX11_RS14425	COG3162	membrane
CXX11_RS14430	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CXX11_RS14440	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CXX11_RS14445	COG0437	4 iron, 4 sulfur cluster binding
CXX11_RS14450	COG3301	Polysulphide reductase, NrfD
CXX11_RS14455	COG1138	Cytochrome C-type biogenesis protein
CXX11_RS14460	COG3088	subunit of a heme lyase
CXX11_RS14465	COG4235	cytochrome complex assembly
CXX11_RS14470	COG1301	dicarboxylic acid transport
CXX11_RS14475	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CXX11_RS14490	COG1289	transmembrane transporter activity
CXX11_RS14495	COG1566	PFAM secretion protein HlyD family protein
CXX11_RS14505	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CXX11_RS14510	COG1940	carbohydrate kinase activity
CXX11_RS14515	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CXX11_RS14520	COG1172	Belongs to the binding-protein-dependent transport system permease family
CXX11_RS14525	COG1129	ABC transporter
CXX11_RS14535	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CXX11_RS14540	COG0456	acetyltransferase
CXX11_RS14545	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CXX11_RS14550	COG3454	Phosphonate metabolism
CXX11_RS14560	COG4107	phosphonate C-P lyase system protein PhnK
CXX11_RS14565	COG3627	carbon phosphorus lyase activity
CXX11_RS14570	COG3626	phosphonate metabolism
CXX11_RS14575	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CXX11_RS14580	COG3624	Phosphonate C-P lyase system protein PhnG
CXX11_RS14585	COG2188	Transcriptional regulator
CXX11_RS14590	COG3639	organic phosphonate transmembrane transporter activity
CXX11_RS14595	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CXX11_RS14605	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CXX11_RS14610	COG2824	Alkylphosphonate utilization operon protein PhnA
CXX11_RS14635	COG0477	Major facilitator Superfamily
CXX11_RS14645	COG0642	Histidine kinase
CXX11_RS14650	COG0745	RESPONSE REGULATOR receiver
CXX11_RS14655	COG2194	sulfuric ester hydrolase activity
CXX11_RS14665	COG2207	Transcriptional regulator
CXX11_RS14670	COG1982	Orn Lys Arg decarboxylase major
CXX11_RS14675	COG2169	Transcriptional regulator
CXX11_RS14680	COG1486	melibiose metabolic process
CXX11_RS14685	COG2211	Major facilitator Superfamily
CXX11_RS14690	COG3647	Membrane
CXX11_RS14695	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CXX11_RS14695	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CXX11_RS14700	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CXX11_RS14710	COG4565	transcriptional regulatory protein
CXX11_RS14715	COG3290	protein histidine kinase activity
CXX11_RS14720	COG3592	Divergent 4Fe-4S mono-cluster
CXX11_RS14725	COG2388	GCN5-related N-acetyl-transferase
CXX11_RS14755	COG3104	oligopeptide transport
CXX11_RS14760	COG1982	Orn Lys Arg decarboxylase major
CXX11_RS14765	COG0531	amino acid
CXX11_RS14835	COG2916	Histone family protein nucleoid-structuring protein H-NS
CXX11_RS14900	COG0582	viral genome integration into host DNA
CXX11_RS14930	COG1309	transcriptional regulator
CXX11_RS14945	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CXX11_RS14950	COG1027	Aspartate ammonia-lyase
CXX11_RS14955	COG3030	protein affecting phage T7 exclusion by the F plasmid
CXX11_RS14960	COG0531	amino acid
CXX11_RS14985	COG1509	lysine 2,3-aminomutase activity
CXX11_RS14995	COG5510	response to toxic substance
CXX11_RS15000	COG5510	response to toxic substance
CXX11_RS15005	COG2076	Multidrug Resistance protein
CXX11_RS15010	COG3040	lipid binding
CXX11_RS15035	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CXX11_RS15040	COG1053	succinate dehydrogenase
CXX11_RS15065	COG1511	domain protein
CXX11_RS15065	COG3264	Mechanosensitive ion channel
CXX11_RS15105	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CXX11_RS15110	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CXX11_RS15110	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CXX11_RS15115	COG0802	atpase or kinase
CXX11_RS15120	COG0860	N-Acetylmuramoyl-L-alanine amidase
CXX11_RS15140	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CXX11_RS15145	COG0330	HflC and HflK could
CXX11_RS15150	COG0330	HflC and HflK could
CXX11_RS15155	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CXX11_RS15170	COG0557	exoribonuclease II activity
CXX11_RS15175	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CXX11_RS15180	COG3789	protein conserved in bacteria
CXX11_RS15185	COG1842	Phage shock protein A
CXX11_RS15195	COG3766	membrane
CXX11_RS15200	COG5463	Belongs to the UPF0441 family
CXX11_RS15205	COG0754	glutathionylspermidine amidase activity
CXX11_RS15210	COG1960	acyl-CoA dehydrogenase activity
CXX11_RS15220	COG3650	response to hydrogen peroxide
CXX11_RS15225	COG1073	alpha beta
CXX11_RS15240	COG3037	sugar-specific permease SgaT UlaA
CXX11_RS15245	COG3414	Phosphotransferase system galactitol-specific IIB component
CXX11_RS15285	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CXX11_RS15295	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CXX11_RS15305	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CXX11_RS15310	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CXX11_RS15315	COG4670	ketone body catabolic process
CXX11_RS15320	COG1024	Enoyl-CoA hydratase
CXX11_RS15335	COG1309	transcriptional regulator
CXX11_RS15340	COG3061	Opacity-associated protein A
CXX11_RS15350	COG0545	Peptidyl-prolyl cis-trans isomerase
CXX11_RS15355	COG1113	amino acid transport
CXX11_RS15365	COG0697	spore germination
CXX11_RS15370	COG0702	epimerase
CXX11_RS15375	COG1733	regulation of RNA biosynthetic process
CXX11_RS15380	COG0737	Belongs to the 5'-nucleotidase family
CXX11_RS15385	COG1218	3'(2'),5'-bisphosphate nucleotidase
CXX11_RS15390	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CXX11_RS15400	COG1253	flavin adenine dinucleotide binding
CXX11_RS15410	COG0729	surface antigen
CXX11_RS15415	COG2911	Protein conserved in bacteria
CXX11_RS15420	COG2105	PFAM AIG2 family protein
CXX11_RS15425	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CXX11_RS15430	COG1879	ABC-type sugar transport system periplasmic component
CXX11_RS15435	COG1129	ABC transporter
CXX11_RS15440	COG1172	Belongs to the binding-protein-dependent transport system permease family
CXX11_RS15445	COG1172	Belongs to the binding-protein-dependent transport system permease family
CXX11_RS15455	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CXX11_RS15465	COG0312	modulator of DNA gyrase
CXX11_RS15470	COG3783	Cytochrome b(562)
CXX11_RS15475	COG0602	queuosine metabolic process
CXX11_RS15480	COG1328	CTP reductase activity
CXX11_RS15485	COG0366	Alpha amylase catalytic
CXX11_RS15490	COG1263	PTS System
CXX11_RS15490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXX11_RS15495	COG1609	Transcriptional regulator
CXX11_RS15505	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CXX11_RS15510	COG0251	oxidation-reduction process
CXX11_RS15530	COG0251	oxidation-reduction process
CXX11_RS15535	COG1028	Short-chain dehydrogenase reductase Sdr
CXX11_RS15540	COG1309	transcriptional regulator
CXX11_RS15545	COG2731	YhcH YjgK YiaL family protein
CXX11_RS15570	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
CXX11_RS15575	COG0456	acetyltransferase
CXX11_RS15580	COG4269	membrane
CXX11_RS15660	COG0740	serine-type endopeptidase activity
CXX11_RS15705	COG4584	PFAM Integrase catalytic
CXX11_RS15710	COG1484	DNA-dependent DNA replication
CXX11_RS15730	COG5532	Uncharacterized conserved protein (DUF2303)
CXX11_RS15735	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CXX11_RS15765	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CXX11_RS15770	COG1011	Hydrolase
CXX11_RS15775	COG0456	acetyltransferase
CXX11_RS15780	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CXX11_RS15810	COG4114	ferric iron reductase
CXX11_RS15815	COG2197	response regulator
CXX11_RS15820	COG2197	response regulator
CXX11_RS15825	COG2966	Psort location CytoplasmicMembrane, score
CXX11_RS15840	COG1484	DNA-dependent DNA replication
CXX11_RS15855	COG1063	alcohol dehydrogenase
CXX11_RS15860	COG1802	Transcriptional regulator
CXX11_RS15875	COG2271	Major facilitator Superfamily
CXX11_RS15880	COG0840	transmembrane signaling receptor activity
CXX11_RS15885	COG1846	Transcriptional regulator
CXX11_RS15890	COG0179	Fumarylacetoacetate (FAA) hydrolase
CXX11_RS15895	COG1012	belongs to the aldehyde dehydrogenase family
CXX11_RS15900	COG3384	dioxygenase
CXX11_RS15910	COG3971	2-oxopent-4-enoate hydratase activity
CXX11_RS15930	COG2368	4-hydroxyphenylacetate
CXX11_RS15935	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CXX11_RS15940	COG1966	Carbon starvation protein
CXX11_RS15945	COG2879	small protein
CXX11_RS15950	COG0523	cobalamin synthesis protein
CXX11_RS15985	COG0732	type I restriction modification DNA specificity domain
CXX11_RS16000	COG5457	Domain of unknown function (DUF1127)
CXX11_RS16005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CXX11_RS16020	COG2814	Major facilitator Superfamily
CXX11_RS16025	COG2733	membrane
CXX11_RS16030	COG4372	Transposase
CXX11_RS16035	COG3436	PFAM IS66 Orf2 family protein
CXX11_RS16050	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
CXX11_RS16055	COG1924	4 iron, 4 sulfur cluster binding
CXX11_RS16070	COG0477	Major facilitator Superfamily
CXX11_RS16080	COG3366	ferrous iron transmembrane transporter activity
CXX11_RS16085	COG0700	Nucleoside recognition
CXX11_RS16090	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CXX11_RS16095	COG0583	DNA-binding transcription factor activity
CXX11_RS16115	COG2186	Transcriptional regulator
CXX11_RS16120	COG0246	Mannitol dehydrogenase
CXX11_RS16135	COG3539	Fimbrial protein
CXX11_RS16140	COG3539	Fimbrial protein
CXX11_RS16195	COG0433	COG0433 Predicted ATPase
CXX11_RS16200	COG0795	lipopolysaccharide-transporting ATPase activity
CXX11_RS16205	COG0795	lipopolysaccharide-transporting ATPase activity
CXX11_RS16215	COG2927	DNA polymerase III (CHI subunit)
CXX11_RS16220	COG0525	valine-tRNA ligase activity
CXX11_RS16245	COG3772	lysozyme
CXX11_RS16295	COG1403	HNH endonuclease
CXX11_RS16305	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CXX11_RS16315	COG4725	Belongs to the MT-A70-like family
CXX11_RS16325	COG1846	Transcriptional regulator
CXX11_RS16335	COG3646	Phage regulatory protein
CXX11_RS16395	COG4372	Transposase
CXX11_RS16400	COG3436	PFAM IS66 Orf2 family protein
CXX11_RS16445	COG5301	cellulose 1,4-beta-cellobiosidase activity
CXX11_RS16500	COG2823	Periplasmic or secreted lipoprotein
CXX11_RS16510	COG4667	esterase of the alpha-beta hydrolase superfamily
CXX11_RS16515	COG0084	hydrolase, TatD family'
CXX11_RS16520	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CXX11_RS16525	COG1328	CTP reductase activity
CXX11_RS16560	COG3726	membrane protein affecting hemolysin expression
CXX11_RS16565	COG0560	Phosphoserine phosphatase
CXX11_RS16570	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CXX11_RS16575	COG3172	ATPase kinase involved in NAD metabolism
CXX11_RS16575	COG1056	cytidyltransferase-related domain
CXX11_RS16580	COG0488	(ABC) transporter
CXX11_RS16585	COG0741	lytic transglycosylase activity
CXX11_RS16605	COG2207	Transcriptional regulator
CXX11_RS16605	COG3708	Transcriptional regulator
CXX11_RS16610	COG3045	CreA protein
CXX11_RS16615	COG0745	RESPONSE REGULATOR receiver
CXX11_RS16620	COG2205	protein histidine kinase activity
CXX11_RS16625	COG4452	Inner membrane protein CreD
CXX11_RS16630	COG0745	RESPONSE REGULATOR receiver
CXX11_RS16640	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CXX11_RS16650	COG0460	homoserine dehydrogenase
CXX11_RS16650	COG0527	aspartate kinase activity
CXX11_RS16660	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CXX11_RS16675	COG1115	amino acid carrier protein
CXX11_RS16685	COG0521	Mo-molybdopterin cofactor biosynthetic process
CXX11_RS16690	COG1584	GPR1 FUN34 yaaH family protein
CXX11_RS16695	COG4735	regulation of single-species biofilm formation
CXX11_RS16715	COG3385	transposase activity
CXX11_RS16735	COG0583	DNA-binding transcription factor activity
CXX11_RS16765	COG0196	riboflavin kinase activity
CXX11_RS16780	COG1047	Peptidyl-prolyl cis-trans
CXX11_RS16800	COG0505	Belongs to the CarA family
CXX11_RS16805	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CXX11_RS16855	COG0644	oxidoreductase
CXX11_RS16860	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CXX11_RS16865	COG2271	Major facilitator Superfamily
CXX11_RS16880	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CXX11_RS16905	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CXX11_RS16910	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CXX11_RS16915	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CXX11_RS16920	COG0564	pseudouridine synthase activity
CXX11_RS16930	COG0417	DNA replication proofreading
CXX11_RS16935	COG0235	Class ii aldolase
CXX11_RS16950	COG4977	sequence-specific DNA binding
CXX11_RS16955	COG0586	Pfam SNARE associated Golgi protein
CXX11_RS16965	COG1178	ABC-type Fe3 transport system permease component
CXX11_RS16970	COG4143	(ABC) transporter
CXX11_RS16985	COG2814	Major facilitator Superfamily
CXX11_RS17000	COG0473	3-isopropylmalate dehydrogenase activity
CXX11_RS17015	COG0583	DNA-binding transcription factor activity
CXX11_RS17025	COG0028	Belongs to the TPP enzyme family
CXX11_RS17030	COG0440	acetolactate synthase activity
CXX11_RS17040	COG1609	Transcriptional regulator
CXX11_RS17045	COG2001	Belongs to the MraZ family
CXX11_RS17055	COG3116	cell division
CXX11_RS17060	COG0768	penicillin binding
CXX11_RS17065	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CXX11_RS17070	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CXX11_RS17080	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CXX11_RS17085	COG0772	Belongs to the SEDS family
CXX11_RS17100	COG1181	Belongs to the D-alanine--D-alanine ligase family
CXX11_RS17105	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CXX11_RS17110	COG0849	cell division
CXX11_RS17115	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CXX11_RS17145	COG0494	nUDIX hydrolase
CXX11_RS17160	COG0237	dephospho-CoA kinase activity
CXX11_RS17170	COG1459	type II secretion system
CXX11_RS17175	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CXX11_RS17180	COG4969	Belongs to the N-Me-Phe pilin family
CXX11_RS17185	COG0157	Belongs to the NadC ModD family
CXX11_RS17190	COG3023	N-Acetylmuramoyl-L-alanine amidase
CXX11_RS17195	COG3725	Membrane protein required for beta-lactamase induction
CXX11_RS17200	COG1113	amino acid transport
CXX11_RS17205	COG2186	Transcriptional regulator
CXX11_RS17210	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CXX11_RS17215	COG0508	dehydrogenase complex catalyzes the overall conversion of
CXX11_RS17220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CXX11_RS17225	COG3064	Membrane
CXX11_RS17230	COG1049	propionate catabolic process, 2-methylcitrate cycle
CXX11_RS17255	COG2132	Multicopper oxidase
CXX11_RS17265	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CXX11_RS17270	COG0288	reversible hydration of carbon dioxide
CXX11_RS17275	COG1131	(ABC) transporter
CXX11_RS17280	COG0842	Transport permease protein
CXX11_RS17285	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX11_RS17290	COG0726	polysaccharide deacetylase
CXX11_RS17315	COG3539	Fimbrial protein
CXX11_RS17320	COG3539	Fimbrial protein
CXX11_RS17325	COG3539	Fimbrial protein
CXX11_RS17330	COG3539	Fimbrial protein
CXX11_RS17340	COG3121	Chaperone
CXX11_RS17345	COG3539	Fimbrial protein
CXX11_RS17350	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CXX11_RS17355	COG0617	tRNA 3'-terminal CCA addition
CXX11_RS17365	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CXX11_RS17375	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CXX11_RS17380	COG1643	Atp-dependent helicase
CXX11_RS17385	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CXX11_RS17390	COG4774	siderophore transport
CXX11_RS17395	COG1120	ATPase activity
CXX11_RS17400	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CXX11_RS17405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CXX11_RS17430	COG2860	membrane
CXX11_RS17435	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CXX11_RS17450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CXX11_RS17455	COG3835	regulator
CXX11_RS17470	COG1408	metallophosphoesterase
CXX11_RS17485	COG0024	Methionine aminopeptidase
CXX11_RS17510	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CXX11_RS17515	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CXX11_RS17520	COG0575	Belongs to the CDS family
CXX11_RS17525	COG0750	zinc metalloprotease
CXX11_RS17535	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CXX11_RS17540	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CXX11_RS17565	COG0587	DNA-directed DNA polymerase activity
CXX11_RS17575	COG1982	Orn Lys Arg decarboxylase major
CXX11_RS17580	COG0346	lactoylglutathione lyase activity
CXX11_RS17585	COG0037	tRNA processing
CXX11_RS17590	COG4568	rho-dependent transcription termination
CXX11_RS17600	COG4681	YaeQ
CXX11_RS17605	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CXX11_RS17610	COG3015	lipoprotein NlpE involved in copper resistance
CXX11_RS17615	COG0791	NLP P60 protein
CXX11_RS17625	COG1720	tRNA m6t6A37 methyltransferase activity
CXX11_RS17635	COG1464	Belongs to the NlpA lipoprotein family
CXX11_RS17640	COG2011	ABC-type metal ion transport system permease component
CXX11_RS17645	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CXX11_RS17650	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CXX11_RS17685	COG0656	L-ascorbic acid biosynthetic process
CXX11_RS17690	COG0583	DNA-binding transcription factor activity
CXX11_RS17700	COG2226	methyltransferase
CXX11_RS17715	COG1388	LysM domain
CXX11_RS17715	COG0741	lytic transglycosylase activity
CXX11_RS17725	COG2226	methyltransferase
CXX11_RS17735	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CXX11_RS17755	COG4104	PAAR repeat-containing protein
CXX11_RS17765	COG3157	Type VI secretion system effector, Hcp
CXX11_RS17865	COG3209	COG3209 Rhs family protein
CXX11_RS17875	COG5433	transposase activity
CXX11_RS17880	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CXX11_RS17890	COG1960	acyl-CoA dehydrogenase activity
CXX11_RS17900	COG0121	glutamine amidotransferase
CXX11_RS17905	COG3034	peptidoglycan biosynthetic process
CXX11_RS17910	COG3041	Addiction module toxin RelE StbE family
CXX11_RS17920	COG3041	Addiction module toxin RelE StbE family
CXX11_RS17925	COG3077	Addiction module antitoxin, RelB DinJ family
CXX11_RS17935	COG1943	Transposase
CXX11_RS17955	COG2161	toxin-antitoxin pair type II binding
CXX11_RS17975	COG1690	Belongs to the RtcB family
CXX11_RS17980	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CXX11_RS17985	COG2195	Cleaves the N-terminal amino acid of tripeptides
CXX11_RS18005	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CXX11_RS18030	COG0582	viral genome integration into host DNA
CXX11_RS18080	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CXX11_RS18085	COG2207	Transcriptional regulator
CXX11_RS18090	COG0247	lactate metabolic process
CXX11_RS18095	COG1139	Iron-sulfur cluster binding protein
CXX11_RS18100	COG1556	Lactate utilization protein
CXX11_RS18135	COG2771	luxR family
CXX11_RS18135	COG2200	EAL domain
CXX11_RS18140	COG0583	DNA-binding transcription factor activity
CXX11_RS18150	COG0666	response to abiotic stimulus
CXX11_RS18160	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CXX11_RS18165	COG1304	FMN binding
CXX11_RS18175	COG0549	Belongs to the carbamate kinase family
CXX11_RS18180	COG0402	S-adenosylhomocysteine deaminase activity
CXX11_RS18185	COG1064	alcohol dehydrogenase
CXX11_RS18200	COG1280	lysine exporter protein (LysE YggA)
CXX11_RS18210	COG3829	transcription factor binding
CXX11_RS18215	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CXX11_RS18220	COG0372	Belongs to the citrate synthase family
CXX11_RS18230	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CXX11_RS18235	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CXX11_RS18240	COG0402	S-adenosylhomocysteine deaminase activity
CXX11_RS18245	COG0583	DNA-binding transcription factor activity
CXX11_RS18250	COG0288	reversible hydration of carbon dioxide
CXX11_RS18260	COG2807	transmembrane transport
CXX11_RS18265	COG0110	maltose O-acetyltransferase activity
CXX11_RS18270	COG2223	nitrite transmembrane transporter activity
CXX11_RS18275	COG3250	beta-galactosidase activity
CXX11_RS18280	COG1609	Transcriptional regulator
CXX11_RS18285	COG1414	Transcriptional regulator
CXX11_RS18305	COG3971	2-oxopent-4-enoate hydratase activity
CXX11_RS18320	COG2814	Major facilitator Superfamily
CXX11_RS18325	COG3122	Protein conserved in bacteria
CXX11_RS18355	COG1215	transferase activity, transferring glycosyl groups
CXX11_RS18360	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CXX11_RS18370	COG4521	taurine ABC transporter
CXX11_RS18375	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CXX11_RS18380	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CXX11_RS18385	COG2175	clavaminate synthase activity
CXX11_RS18390	COG0113	porphobilinogen synthase activity
CXX11_RS18400	COG3468	outer membrane autotransporter barrel domain protein
CXX11_RS18405	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CXX11_RS18410	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CXX11_RS18415	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CXX11_RS18435	COG1181	Belongs to the D-alanine--D-alanine ligase family
CXX11_RS18450	COG1785	Belongs to the alkaline phosphatase family
CXX11_RS18460	COG3706	GGDEF domain
CXX11_RS18465	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CXX11_RS18485	COG4126	flavin adenine dinucleotide binding
CXX11_RS18510	COG1940	carbohydrate kinase activity
CXX11_RS18515	COG2814	Major facilitator Superfamily
CXX11_RS18520	COG0419	ATPase involved in DNA repair
CXX11_RS18525	COG0420	3'-5' exonuclease activity
CXX11_RS18530	COG0745	RESPONSE REGULATOR receiver
CXX11_RS18535	COG5002	protein histidine kinase activity
CXX11_RS18540	COG1114	Component of the transport system for branched-chain amino acids
CXX11_RS18545	COG1113	amino acid transport
CXX11_RS18550	COG0366	Alpha amylase catalytic
CXX11_RS18570	COG1862	Preprotein translocase
CXX11_RS18575	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CXX11_RS18580	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CXX11_RS18585	COG1403	HNH endonuclease
CXX11_RS18590	COG3248	Nucleoside-binding outer membrane protein
CXX11_RS18595	COG4238	major outer membrane lipoprotein
CXX11_RS18605	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CXX11_RS18605	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CXX11_RS18620	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CXX11_RS18625	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CXX11_RS18630	COG0667	Aldo Keto reductase
CXX11_RS18640	COG0142	geranyltranstransferase activity
CXX11_RS18655	COG0693	protein deglycase activity
CXX11_RS18660	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CXX11_RS18670	COG2814	Major facilitator Superfamily
CXX11_RS18695	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CXX11_RS18700	COG1845	cytochrome c oxidase, subunit III
CXX11_RS18705	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CXX11_RS18710	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CXX11_RS18715	COG2223	nitrite transmembrane transporter activity
CXX11_RS18720	COG3056	Lipoprotein
CXX11_RS18725	COG0271	Belongs to the BolA IbaG family
CXX11_RS18745	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CXX11_RS18750	COG0776	regulation of translation
CXX11_RS18755	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CXX11_RS18760	COG1555	photosystem II stabilization
CXX11_RS18765	COG0824	Thioesterase
CXX11_RS18795	COG1522	sequence-specific DNA binding
CXX11_RS18800	COG1132	(ABC) transporter
CXX11_RS18805	COG1132	(ABC) transporter
CXX11_RS18810	COG0347	Belongs to the P(II) protein family
CXX11_RS18815	COG0004	ammonium transporteR
CXX11_RS18820	COG1946	Acyl-CoA thioesterase
CXX11_RS18825	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CXX11_RS18830	COG3695	enzyme binding
CXX11_RS18840	COG5507	3-demethylubiquinone-9 3-methyltransferase
CXX11_RS18845	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CXX11_RS18855	COG0110	maltose O-acetyltransferase activity
CXX11_RS18870	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CXX11_RS18875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CXX11_RS18880	COG1309	transcriptional regulator
CXX11_RS18885	COG1196	nuclear chromosome segregation
CXX11_RS18885	COG3264	Mechanosensitive ion channel
CXX11_RS18895	COG3923	Primosomal replication protein n
CXX11_RS18900	COG2832	Protein of unknown function (DUF454)
CXX11_RS18910	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CXX11_RS18945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CXX11_RS18950	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CXX11_RS18950	COG4651	solute:proton antiporter activity
CXX11_RS18955	COG2223	nitrite transmembrane transporter activity
CXX11_RS18960	COG0737	Belongs to the 5'-nucleotidase family
CXX11_RS18965	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CXX11_RS18970	COG3735	TraB family
CXX11_RS18980	COG3093	addiction module antidote protein HigA
CXX11_RS18985	COG2217	Heavy metal translocating P-type atpase
CXX11_RS18995	COG0531	amino acid
CXX11_RS19000	COG0789	Transcriptional regulator
CXX11_RS19005	COG1585	Membrane protein implicated in regulation of membrane protease activity
CXX11_RS19010	COG0330	HflC and HflK could
CXX11_RS19015	COG4619	ABC transporter
CXX11_RS19020	COG0390	transport system, permease component
CXX11_RS19025	COG3118	belongs to the thioredoxin family
CXX11_RS19030	COG0300	oxidoreductase activity
CXX11_RS19035	COG2755	lipolytic protein G-D-S-L family
CXX11_RS19040	COG4181	ATPase activity
CXX11_RS19045	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CXX11_RS19050	COG3209	COG3209 Rhs family protein
CXX11_RS19090	COG0583	DNA-binding transcription factor activity
CXX11_RS19100	COG1414	Transcriptional regulator
CXX11_RS19105	COG3960	tartronate-semialdehyde synthase activity
CXX11_RS19110	COG3622	Belongs to the hyi family
CXX11_RS19115	COG2084	Dehydrogenase
CXX11_RS19120	COG1953	Uracil, thiamine, allantoin
CXX11_RS19130	COG2233	PERMEase
CXX11_RS19135	COG1929	Belongs to the glycerate kinase type-1 family
CXX11_RS19140	COG3257	ureidoglycine aminohydrolase activity
CXX11_RS19145	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CXX11_RS19150	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CXX11_RS19155	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CXX11_RS19160	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CXX11_RS19170	COG0549	Belongs to the carbamate kinase family
CXX11_RS19175	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CXX11_RS19180	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CXX11_RS19190	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CXX11_RS19200	COG1988	membrane-bound metal-dependent
CXX11_RS19205	COG2501	S4 domain
CXX11_RS19215	COG3539	Fimbrial protein
CXX11_RS19230	COG0582	viral genome integration into host DNA
CXX11_RS19300	COG3772	lysozyme
CXX11_RS19315	COG4372	Transposase
CXX11_RS19320	COG3436	PFAM IS66 Orf2 family protein
CXX11_RS19350	COG2207	Transcriptional regulator
CXX11_RS19365	COG1215	transferase activity, transferring glycosyl groups
CXX11_RS19370	COG5433	transposase activity
CXX11_RS19395	COG3209	COG3209 Rhs family protein
CXX11_RS19395	COG4104	PAAR repeat-containing protein
CXX11_RS19405	COG3501	Rhs element vgr protein
CXX11_RS19410	COG5002	protein histidine kinase activity
CXX11_RS19415	COG0745	RESPONSE REGULATOR receiver
CXX11_RS19420	COG1538	Outer membrane efflux protein
CXX11_RS19425	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CXX11_RS19430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CXX11_RS19435	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CXX11_RS19440	COG1113	amino acid transport
CXX11_RS19445	COG0668	transmembrane transport
CXX11_RS19450	COG0778	Nitroreductase
CXX11_RS19455	COG2315	Protein conserved in bacteria
CXX11_RS19480	COG3385	transposase activity
CXX11_RS19485	COG2977	Belongs to the P-Pant transferase superfamily
CXX11_RS19490	COG4771	TonB-dependent receptor
CXX11_RS19495	COG2382	esterase
CXX11_RS19500	COG3251	PFAM MbtH domain protein
CXX11_RS19505	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXX11_RS19505	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CXX11_RS19520	COG1120	ATPase activity
CXX11_RS19525	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CXX11_RS19530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CXX11_RS19540	COG4592	Periplasmic binding protein
CXX11_RS19545	COG1169	isochorismate synthase
CXX11_RS19550	COG1021	2,3-dihydroxybenzoate-AMP ligase
CXX11_RS19555	COG1535	isochorismatase
CXX11_RS19555	COG3433	isochorismatase activity
CXX11_RS19560	COG1028	Short-chain dehydrogenase reductase Sdr
CXX11_RS19565	COG2050	protein possibly involved in aromatic compounds catabolism
CXX11_RS19570	COG1966	Carbon starvation protein
CXX11_RS19575	COG2879	small protein
CXX11_RS19580	COG0371	Dehydrogenase
CXX11_RS19585	COG0436	Aminotransferase
CXX11_RS19590	COG1475	DNA binding
CXX11_RS19595	COG3969	phosphoadenosine phosphosulfate
CXX11_RS19605	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CXX11_RS19610	COG0450	alkyl hydroperoxide reductase
CXX11_RS19615	COG3634	alkyl hydroperoxide reductase activity
CXX11_RS19620	COG0589	response to stress
CXX11_RS19625	COG1063	alcohol dehydrogenase
CXX11_RS19630	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CXX11_RS19635	COG3719	Belongs to the RNase T2 family
CXX11_RS19640	COG0471	metal ion transport
CXX11_RS19655	COG3051	citrate lyase alpha subunit
CXX11_RS19660	COG2301	Belongs to the HpcH HpaI aldolase family
CXX11_RS19670	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
CXX11_RS19675	COG3290	protein histidine kinase activity
CXX11_RS19680	COG4565	transcriptional regulatory protein
CXX11_RS19685	COG3069	C4-dicarboxylate transmembrane transporter activity
CXX11_RS19705	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CXX11_RS19710	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CXX11_RS19720	COG0583	DNA-binding transcription factor activity
CXX11_RS19735	COG1686	Belongs to the peptidase S11 family
CXX11_RS19740	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CXX11_RS19745	COG0772	Belongs to the SEDS family
CXX11_RS19750	COG0768	penicillin binding
CXX11_RS19760	COG0799	negative regulation of ribosome biogenesis
CXX11_RS19765	COG0406	alpha-ribazole phosphatase activity
CXX11_RS19775	COG1466	dna polymerase III delta subunit
CXX11_RS19790	COG2888	peptidyl-tyrosine sulfation
CXX11_RS19795	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CXX11_RS19805	COG2214	Heat shock protein DnaJ domain protein
CXX11_RS19810	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CXX11_RS19820	COG2214	Heat shock protein DnaJ domain protein
CXX11_RS19825	COG0443	Heat shock 70 kDa protein
CXX11_RS19835	COG1126	abc transporter atp-binding protein
CXX11_RS19840	COG0765	amino acid transport
CXX11_RS19845	COG0765	amino acid transport
CXX11_RS19850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXX11_RS19865	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CXX11_RS19870	COG4535	Mg2 and Co2 transporter CorC
CXX11_RS19880	COG1702	phosphate starvation-inducible protein PhoH
CXX11_RS19890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CXX11_RS19930	COG0367	asparagine synthase
CXX11_RS19935	COG0647	UMP catabolic process
CXX11_RS19940	COG1940	carbohydrate kinase activity
CXX11_RS19940	COG1846	Transcriptional regulator
CXX11_RS19945	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CXX11_RS19955	COG2190	(PTS) system
CXX11_RS19955	COG1263	PTS System
CXX11_RS19955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXX11_RS19975	COG0735	belongs to the Fur family
CXX11_RS19985	COG0716	FMN binding
CXX11_RS19995	COG0596	Alpha beta hydrolase
CXX11_RS20000	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CXX11_RS20005	COG0033	Phosphoglucomutase
CXX11_RS20025	COG0531	amino acid
CXX11_RS20030	COG1982	Orn Lys Arg decarboxylase major
CXX11_RS20045	COG0745	RESPONSE REGULATOR receiver
CXX11_RS20050	COG2205	protein histidine kinase activity
CXX11_RS20080	COG3209	COG3209 Rhs family protein
CXX11_RS20135	COG3272	Protein of unknown function (DUF1722)
CXX11_RS20140	COG0415	Belongs to the DNA photolyase family
CXX11_RS20150	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CXX11_RS20155	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CXX11_RS20160	COG1984	allophanate hydrolase subunit 2
CXX11_RS20175	COG3180	Ammonia monooxygenase
CXX11_RS20180	COG3539	Fimbrial protein
CXX11_RS20185	COG3121	Chaperone
CXX11_RS20190	COG3188	usher protein
CXX11_RS20195	COG3539	Fimbrial protein
CXX11_RS20200	COG0372	Belongs to the citrate synthase family
CXX11_RS20210	COG2009	succinate dehydrogenase
CXX11_RS20215	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CXX11_RS20220	COG1053	succinate dehydrogenase
CXX11_RS20225	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CXX11_RS20230	COG0567	Dehydrogenase, E1 component
CXX11_RS20235	COG0508	dehydrogenase complex catalyzes the overall conversion of
CXX11_RS20245	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CXX11_RS20250	COG2188	Transcriptional regulator
CXX11_RS20255	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CXX11_RS20255	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CXX11_RS20255	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX11_RS20260	COG0383	alpha-mannosidase activity
CXX11_RS20270	COG1271	oxidase subunit
CXX11_RS20275	COG1294	oxidase, subunit
CXX11_RS20280	COG4890	Cyd operon protein YbgT
CXX11_RS20285	COG3790	cyd operon protein YbgE
CXX11_RS20290	COG0824	Thioesterase
CXX11_RS20295	COG0811	peptide transport
CXX11_RS20300	COG0848	biopolymer transport protein
CXX11_RS20305	COG3064	Membrane
CXX11_RS20315	COG2885	chlorophyll binding
CXX11_RS20320	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CXX11_RS20365	COG3201	nicotinamide mononucleotide transporter
CXX11_RS20370	COG1230	cation diffusion facilitator family transporter
CXX11_RS20380	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CXX11_RS20390	COG2017	converts alpha-aldose to the beta-anomer
CXX11_RS20400	COG1085	galactose-1-phosphate uridylyltransferase
CXX11_RS20405	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CXX11_RS20410	COG1119	ATPase activity
CXX11_RS20415	COG2005	Transcriptional regulator
CXX11_RS20415	COG3585	molybdate ion transport
CXX11_RS20425	COG0725	ABC transporter, periplasmic molybdate-binding protein
CXX11_RS20430	COG4149	molybdate abc transporter
CXX11_RS20435	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CXX11_RS20440	COG0561	phosphatase activity
CXX11_RS20455	COG2828	Protein conserved in bacteria
CXX11_RS20460	COG0471	metal ion transport
CXX11_RS20480	COG4677	pectinesterase activity
CXX11_RS20485	COG1881	PFAM PEBP family protein
CXX11_RS20490	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CXX11_RS20505	COG2226	methyltransferase
CXX11_RS20510	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CXX11_RS20525	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CXX11_RS20535	COG0521	Mo-molybdopterin cofactor biosynthetic process
CXX11_RS20545	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CXX11_RS20550	COG0314	molybdopterin synthase activity
CXX11_RS20555	COG0670	Belongs to the BI1 family
CXX11_RS20570	COG0392	lysyltransferase activity
CXX11_RS20575	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CXX11_RS20580	COG3568	Endonuclease Exonuclease Phosphatase
CXX11_RS20590	COG0842	Transport permease protein
CXX11_RS20595	COG0842	Transport permease protein
CXX11_RS20600	COG1131	(ABC) transporter
CXX11_RS20610	COG1309	transcriptional regulator
CXX11_RS20615	COG0513	Belongs to the DEAD box helicase family
CXX11_RS20620	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
CXX11_RS20625	COG1199	ATP-dependent helicase activity
CXX11_RS20630	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CXX11_RS20635	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CXX11_RS20645	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CXX11_RS20660	COG4774	siderophore transport
CXX11_RS20675	COG0668	transmembrane transport
CXX11_RS20680	COG1126	abc transporter atp-binding protein
CXX11_RS20685	COG0765	amino acid transport
CXX11_RS20690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXX11_RS20700	COG5006	permease, DMT superfamily
CXX11_RS20710	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CXX11_RS20715	COG2194	sulfuric ester hydrolase activity
CXX11_RS20725	COG1321	iron dependent repressor
CXX11_RS20730	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CXX11_RS20735	COG1376	ErfK ybiS ycfS ynhG family protein
CXX11_RS20740	COG0488	(ABC) transporter
CXX11_RS20750	COG0561	phosphatase activity
CXX11_RS20755	COG1882	Formate acetyltransferase
CXX11_RS20760	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CXX11_RS20765	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CXX11_RS20770	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CXX11_RS20775	COG0303	'Molybdopterin
CXX11_RS20780	COG1446	asparaginase
CXX11_RS20790	COG0747	negative chemotaxis
CXX11_RS20815	COG2200	EAL domain
CXX11_RS20820	COG2199	diguanylate cyclase activity
CXX11_RS20845	COG2133	pyrroloquinoline quinone binding
CXX11_RS20850	COG0625	glutathione transferase activity
CXX11_RS20855	COG1686	Belongs to the peptidase S11 family
CXX11_RS20860	COG1349	DNA-binding transcription factor activity
CXX11_RS20865	COG0671	phosphoesterase, PA-phosphatase related
CXX11_RS20870	COG2814	Major facilitator Superfamily
CXX11_RS20880	COG0561	phosphatase activity
CXX11_RS20885	COG0738	Major facilitator superfamily
CXX11_RS20890	COG3226	Transcriptional regulator
CXX11_RS20905	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CXX11_RS20915	COG0778	Nitroreductase
CXX11_RS20930	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CXX11_RS20935	COG3842	ATPase activity
CXX11_RS20940	COG1176	ABC-type spermidine putrescine transport system, permease component I
CXX11_RS20945	COG1177	transmembrane transport
CXX11_RS20970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXX11_RS20975	COG4160	amino acid transport
CXX11_RS20980	COG4215	(ABC) transporter
CXX11_RS20985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXX11_RS20990	COG1126	abc transporter atp-binding protein
CXX11_RS21005	COG3023	N-Acetylmuramoyl-L-alanine amidase
CXX11_RS21010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CXX11_RS21015	COG0702	epimerase
CXX11_RS21020	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CXX11_RS21025	COG0028	Belongs to the TPP enzyme family
CXX11_RS21030	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CXX11_RS21040	COG2431	L-lysine efflux transmembrane transporter activity
CXX11_RS21055	COG3593	DNA synthesis involved in DNA repair
CXX11_RS21060	COG2990	Protein conserved in bacteria
CXX11_RS21065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CXX11_RS21070	COG0577	efflux transmembrane transporter activity
CXX11_RS21070	COG1136	(ABC) transporter
CXX11_RS21075	COG1278	Cold shock
CXX11_RS21085	COG0542	response to heat
CXX11_RS21110	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CXX11_RS21115	COG4988	ABC transporter
CXX11_RS21120	COG0492	ferredoxin-NADP+ reductase activity
CXX11_RS21125	COG1522	sequence-specific DNA binding
CXX11_RS21130	COG1674	ftsk spoiiie
CXX11_RS21130	COG1178	ABC-type Fe3 transport system permease component
CXX11_RS21140	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CXX11_RS21150	COG0243	molybdopterin cofactor binding
CXX11_RS21155	COG0437	4 iron, 4 sulfur cluster binding
CXX11_RS21160	COG3302	dmso reductase anchor subunit
CXX11_RS21165	COG1335	isochorismatase
CXX11_RS21175	COG0531	amino acid
CXX11_RS21180	COG0583	DNA-binding transcription factor activity
CXX11_RS21200	COG2249	NAD(P)H dehydrogenase (quinone) activity
CXX11_RS21205	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CXX11_RS21210	COG1882	Formate acetyltransferase
CXX11_RS21215	COG2116	formate transmembrane transporter activity
CXX11_RS21220	COG1944	ATP diphosphatase activity
CXX11_RS21225	COG2323	membrane
CXX11_RS21240	COG0501	Belongs to the peptidase M48B family
CXX11_RS21250	COG0539	negative regulation of cytoplasmic translation
CXX11_RS21260	COG0658	competence protein
CXX11_RS21260	COG2333	competence protein COMEC
CXX11_RS21265	COG1132	(ABC) transporter
CXX11_RS21275	COG3214	Protein conserved in bacteria
CXX11_RS21290	COG3173	Aminoglycoside phosphotransferase
CXX11_RS21295	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CXX11_RS21300	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CXX11_RS21310	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CXX11_RS21320	COG2989	Protein conserved in bacteria
CXX11_RS21325	COG3108	Peptidase M15
CXX11_RS21330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CXX11_RS21335	COG1448	Aminotransferase
CXX11_RS21355	COG0308	aminopeptidase N
CXX11_RS21360	COG1116	anion transmembrane transporter activity
CXX11_RS21365	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CXX11_RS21375	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CXX11_RS21380	COG0431	NADPH-dependent FMN reductase
CXX11_RS21385	COG3539	Fimbrial protein
CXX11_RS21390	COG3121	Chaperone
CXX11_RS21395	COG3188	usher protein
CXX11_RS21400	COG3539	Fimbrial protein
CXX11_RS21405	COG3539	Fimbrial protein
CXX11_RS21410	COG3539	Fimbrial protein
CXX11_RS21415	COG3121	Chaperone
CXX11_RS21435	COG3217	Mosc domain protein beta barrel domain protein
CXX11_RS21435	COG0633	Ferredoxin
CXX11_RS21445	COG0488	(ABC) transporter
CXX11_RS21450	COG2995	paraquat-inducible protein a
CXX11_RS21455	COG3008	intermembrane lipid transfer
CXX11_RS21455	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CXX11_RS21460	COG3009	Protein conserved in bacteria
CXX11_RS21465	COG3130	regulation of translation
CXX11_RS21475	COG1067	ATP-dependent peptidase activity
CXX11_RS21495	COG3070	regulator of competence-specific genes
CXX11_RS21500	COG1289	transmembrane transporter activity
CXX11_RS21505	COG3304	Inner membrane component domain
CXX11_RS21510	COG0210	DNA helicase
CXX11_RS21525	COG1832	CoA-binding protein
CXX11_RS21540	COG1254	Belongs to the acylphosphatase family
CXX11_RS21545	COG2920	part of a sulfur-relay system
CXX11_RS21550	COG0670	Belongs to the BI1 family
CXX11_RS21560	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CXX11_RS21565	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CXX11_RS21570	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
CXX11_RS21575	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CXX11_RS21580	COG1999	signal sequence binding
CXX11_RS21585	COG1773	rubredoxin
CXX11_RS21590	COG1271	oxidase subunit
CXX11_RS21595	COG1294	oxidase, subunit
CXX11_RS21610	COG1278	Cold shock
CXX11_RS21615	COG1278	Cold shock
CXX11_RS21645	COG1879	ABC-type sugar transport system periplasmic component
CXX11_RS21650	COG0745	RESPONSE REGULATOR receiver
CXX11_RS21655	COG3005	denitrification pathway
CXX11_RS21660	COG0243	molybdopterin cofactor binding
CXX11_RS21700	COG3729	General stress protein
CXX11_RS21705	COG2233	PERMEase
CXX11_RS21730	COG1335	isochorismatase
CXX11_RS21740	COG1309	transcriptional regulator
CXX11_RS21745	COG0506	proline dehydrogenase activity
CXX11_RS21745	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CXX11_RS21745	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CXX11_RS21755	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CXX11_RS21765	COG2822	iron ion transport
CXX11_RS21770	COG2837	iron assimilation
CXX11_RS21775	COG1702	phosphate starvation-inducible protein PhoH
CXX11_RS21780	COG3658	cytochrome
CXX11_RS21785	COG1215	transferase activity, transferring glycosyl groups
CXX11_RS21790	COG1649	PFAM Uncharacterised BCR, COG1649
CXX11_RS21790	COG0726	polysaccharide deacetylase
CXX11_RS21795	COG0457	Tetratricopeptide repeat
CXX11_RS21800	COG3706	GGDEF domain
CXX11_RS21845	COG3381	protein complex oligomerization
CXX11_RS21855	COG1462	curli production assembly transport component CsgG
CXX11_RS21870	COG2197	response regulator
CXX11_RS21895	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CXX11_RS21900	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CXX11_RS21915	COG2943	transferase activity, transferring hexosyl groups
CXX11_RS21920	COG5645	(Lipo)protein
CXX11_RS21935	COG1560	Kdo2-lipid A biosynthetic process
CXX11_RS21945	COG2353	YceI-like domain
CXX11_RS21950	COG3038	cytochrome b561
CXX11_RS21985	COG2999	glutathione oxidoreductase activity
CXX11_RS21995	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CXX11_RS22005	COG0673	inositol 2-dehydrogenase activity
CXX11_RS22010	COG0728	peptidoglycan biosynthetic process
CXX11_RS22015	COG3418	PFAM FlgN family protein
CXX11_RS22020	COG2747	anti-sigma28 factor FlgM
CXX11_RS22025	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
CXX11_RS22030	COG1815	bacterial-type flagellum-dependent cell motility
CXX11_RS22035	COG1558	bacterial-type flagellum-dependent cell motility
CXX11_RS22040	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CXX11_RS22045	COG1749	Flagellar hook protein flgE
CXX11_RS22050	COG4787	bacterial-type flagellum-dependent cell motility
CXX11_RS22055	COG4786	Flagellar basal body rod
CXX11_RS22070	COG1705	Flagellar rod assembly protein muramidase FlgJ
CXX11_RS22070	COG3951	Flagellar rod assembly protein muramidase FlgJ
CXX11_RS22075	COG1256	bacterial-type flagellum assembly
CXX11_RS22080	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CXX11_RS22085	COG1530	ribonuclease E activity
CXX11_RS22095	COG0564	pseudouridine synthase activity
CXX11_RS22100	COG0424	maF-like protein
CXX11_RS22105	COG1399	metal-binding, possibly nucleic acid-binding protein
CXX11_RS22125	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CXX11_RS22130	COG1028	Short-chain dehydrogenase reductase Sdr
CXX11_RS22140	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CXX11_RS22145	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CXX11_RS22150	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CXX11_RS22160	COG0470	DNA polymerase III
CXX11_RS22165	COG0084	hydrolase, TatD family'
CXX11_RS22170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXX11_RS22170	COG1263	PTS System
CXX11_RS22180	COG0537	adenosine 5'-monophosphoramidase activity
CXX11_RS22185	COG5633	Lipoprotein
CXX11_RS22190	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
CXX11_RS22210	COG1252	NADH dehydrogenase
CXX11_RS22215	COG3134	Outer membrane lipoprotein
CXX11_RS22220	COG1309	transcriptional regulator
CXX11_RS22240	COG1388	LysM domain
CXX11_RS22240	COG1376	ErfK ybiS ycfS ynhG family protein
CXX11_RS22245	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CXX11_RS22250	COG4763	Acyl-transferase
CXX11_RS22255	COG4591	ABC-type transport system involved in lipoprotein release permease component
CXX11_RS22265	COG4591	ABC-type transport system involved in lipoprotein release permease component
CXX11_RS22275	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CXX11_RS22280	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CXX11_RS22285	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CXX11_RS22295	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CXX11_RS22300	COG1177	transmembrane transport
CXX11_RS22320	COG2850	peptidyl-arginine hydroxylation
CXX11_RS22325	COG2205	protein histidine kinase activity
CXX11_RS22330	COG0745	RESPONSE REGULATOR receiver
CXX11_RS22335	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CXX11_RS22355	COG1187	pseudouridine synthase activity
CXX11_RS22360	COG0538	isocitrate dehydrogenase activity
CXX11_RS22375	COG5562	phage envelope protein
CXX11_RS22380	COG0789	Transcriptional regulator
CXX11_RS22385	COG2200	EAL domain
CXX11_RS22410	COG2200	EAL domain
CXX11_RS22480	COG2894	cell division
CXX11_RS22505	COG0179	Fumarylacetoacetate (FAA) hydrolase
CXX11_RS22530	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CXX11_RS22535	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CXX11_RS22540	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CXX11_RS22555	COG2719	SpoVR family
CXX11_RS22565	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CXX11_RS22575	COG1619	proteins homologs of microcin C7 resistance protein MccF
CXX11_RS22585	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CXX11_RS22605	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CXX11_RS22605	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX11_RS22605	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CXX11_RS22610	COG1461	Dihydroxyacetone kinase
CXX11_RS22615	COG2376	Dihydroxyacetone kinase
CXX11_RS22620	COG3284	Transcriptional regulator
CXX11_RS22625	COG3468	outer membrane autotransporter barrel domain protein
CXX11_RS22635	COG0012	GTP binding
CXX11_RS22650	COG0659	secondary active sulfate transmembrane transporter activity
CXX11_RS22655	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CXX11_RS22680	COG2890	protein-(glutamine-N5) methyltransferase activity
CXX11_RS22685	COG3094	Invasion gene expression up-regulator, SirB
CXX11_RS22690	COG2912	Transglutaminase-like superfamily
CXX11_RS22735	COG0387	Pfam Sodium calcium exchanger
CXX11_RS22740	COG4572	Cation transport regulator
CXX11_RS22745	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CXX11_RS22750	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CXX11_RS22755	COG4932	domain protein
CXX11_RS22760	COG2197	response regulator
CXX11_RS22765	COG3850	Histidine kinase
CXX11_RS22770	COG2223	nitrite transmembrane transporter activity
CXX11_RS22775	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CXX11_RS22780	COG1140	nitrate reductase beta subunit
CXX11_RS22785	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CXX11_RS22790	COG2181	nitrate reductase activity
CXX11_RS22820	COG0788	formyltetrahydrofolate deformylase activity
CXX11_RS22830	COG1752	Esterase of the alpha-beta hydrolase superfamily
CXX11_RS22835	COG0745	RESPONSE REGULATOR receiver
CXX11_RS22840	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CXX11_RS22850	COG1435	thymidine kinase activity
CXX11_RS22855	COG1012	belongs to the aldehyde dehydrogenase family
CXX11_RS22855	COG1454	alcohol dehydrogenase
CXX11_RS22860	COG2095	MarC family integral membrane protein
CXX11_RS22875	COG4166	transmembrane transport
CXX11_RS22880	COG0601	transmembrane transport
CXX11_RS22885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CXX11_RS22890	COG0444	Belongs to the ABC transporter superfamily
CXX11_RS22895	COG4608	Belongs to the ABC transporter superfamily
CXX11_RS22915	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CXX11_RS22920	COG2350	Protein conserved in bacteria
CXX11_RS22925	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CXX11_RS22930	COG1607	acyl-coa hydrolase
CXX11_RS22950	COG3047	cAMP biosynthetic process
CXX11_RS22955	COG0582	viral genome integration into host DNA
CXX11_RS22965	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CXX11_RS23015	COG1846	Transcriptional regulator
CXX11_RS23020	COG1484	DNA-dependent DNA replication
CXX11_RS23060	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CXX11_RS23090	COG0582	viral genome integration into host DNA
CXX11_RS23265	COG4220	transposase activity
CXX11_RS23275	COG4584	PFAM Integrase catalytic
CXX11_RS23280	COG1484	DNA-dependent DNA replication
CXX11_RS23300	COG1030	water channel activity
CXX11_RS23350	COG1196	nuclear chromosome segregation
CXX11_RS23400	COG4372	Transposase
CXX11_RS23405	COG3436	PFAM IS66 Orf2 family protein
CXX11_RS23455	COG0500	methyltransferase
CXX11_RS23505	COG3685	Protein conserved in bacteria
CXX11_RS23510	COG3729	General stress protein
CXX11_RS23525	COG0135	phosphoribosylanthranilate isomerase activity
CXX11_RS23525	COG0134	indole-3-glycerol-phosphate synthase activity
CXX11_RS23530	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CXX11_RS23530	COG0512	Glutamine amidotransferase of anthranilate synthase
CXX11_RS23535	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CXX11_RS23545	COG0613	PHP domain protein
CXX11_RS23550	COG0009	L-threonylcarbamoyladenylate synthase
CXX11_RS23560	COG1187	pseudouridine synthase activity
CXX11_RS23565	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CXX11_RS23570	COG1028	Short-chain dehydrogenase reductase Sdr
CXX11_RS23580	COG0616	signal peptide processing
CXX11_RS23590	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CXX11_RS23595	COG0583	DNA-binding transcription factor activity
CXX11_RS23620	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CXX11_RS23630	COG0671	phosphoesterase, PA-phosphatase related
CXX11_RS23635	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CXX11_RS23640	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CXX11_RS23650	COG0023	Translation Initiation Factor
CXX11_RS23660	COG1349	DNA-binding transcription factor activity
CXX11_RS23670	COG5001	Diguanylate cyclase
CXX11_RS23685	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CXX11_RS23685	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CXX11_RS23690	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CXX11_RS23695	COG2852	Protein conserved in bacteria
CXX11_RS23700	COG4172	Belongs to the ABC transporter superfamily
CXX11_RS23705	COG4172	Belongs to the ABC transporter superfamily
CXX11_RS23710	COG4171	peptide transport system, permease
CXX11_RS23715	COG4168	peptide transport system, permease
CXX11_RS23720	COG4166	transmembrane transport
CXX11_RS23730	COG0531	amino acid
CXX11_RS23740	COG0174	glutamine synthetase
CXX11_RS23745	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CXX11_RS23750	COG1396	sequence-specific DNA binding
CXX11_RS23750	COG1917	Cupin 2, conserved barrel domain protein
CXX11_RS23755	COG1012	belongs to the aldehyde dehydrogenase family
CXX11_RS23760	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CXX11_RS23765	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CXX11_RS23770	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CXX11_RS23775	COG1842	Phage shock protein A
CXX11_RS23785	COG1983	PspC domain protein
CXX11_RS23795	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CXX11_RS23800	COG0366	Alpha amylase catalytic
CXX11_RS23815	COG1653	transport
CXX11_RS23820	COG1175	transmembrane transport
CXX11_RS23825	COG0395	ABC-type sugar transport system, permease component
CXX11_RS23830	COG1063	alcohol dehydrogenase
CXX11_RS23835	COG1082	Xylose isomerase domain protein TIM barrel
CXX11_RS23840	COG0673	inositol 2-dehydrogenase activity
CXX11_RS23845	COG1554	hydrolase, family 65, central catalytic
CXX11_RS23850	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CXX11_RS23855	COG3842	ATPase activity
CXX11_RS23865	COG1609	Transcriptional regulator
CXX11_RS23870	COG3106	COG3106 Predicted ATPase
CXX11_RS23880	COG3283	Transcriptional regulator of aromatic amino acids metabolism
CXX11_RS23885	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CXX11_RS23890	COG4948	Mandelate Racemase Muconate Lactonizing
CXX11_RS23895	COG2866	Carboxypeptidase
CXX11_RS23910	COG1073	alpha beta
CXX11_RS23915	COG0583	DNA-binding transcription factor activity
CXX11_RS23920	COG4166	transmembrane transport
CXX11_RS23925	COG0668	transmembrane transport
CXX11_RS23930	COG3182	Iron-regulated membrane protein
CXX11_RS23935	COG0589	response to stress
CXX11_RS23940	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CXX11_RS23945	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CXX11_RS23950	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CXX11_RS23955	COG1473	amidohydrolase
CXX11_RS23960	COG1473	amidohydrolase
CXX11_RS23965	COG0583	DNA-binding transcription factor activity
CXX11_RS23970	COG2840	Smr protein MutS2
CXX11_RS23975	COG3706	GGDEF domain
CXX11_RS23985	COG0513	Belongs to the DEAD box helicase family
CXX11_RS23995	COG0589	response to stress
CXX11_RS24000	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CXX11_RS24005	COG0674	pyruvate-flavodoxin oxidoreductase activity
CXX11_RS24005	COG1013	pyruvate-flavodoxin oxidoreductase activity
CXX11_RS24005	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CXX11_RS24005	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CXX11_RS24010	COG3042	response to heat
CXX11_RS24015	COG3187	Heat shock protein
CXX11_RS24020	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CXX11_RS24025	COG2911	Protein conserved in bacteria
CXX11_RS24035	COG3784	Protein of unknown function (DUF1318)
CXX11_RS24040	COG2207	Transcriptional regulator
CXX11_RS24045	COG1012	belongs to the aldehyde dehydrogenase family
CXX11_RS24050	COG3733	amine oxidase
CXX11_RS24065	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CXX11_RS24200	COG2369	cell adhesion
CXX11_RS24210	COG4373	Mu-like prophage FluMu protein gp28
CXX11_RS24295	COG3409	Peptidoglycan-binding domain 1 protein
CXX11_RS24295	COG3267	Type II secretory pathway component ExeA
CXX11_RS24305	COG4396	Host-nuclease inhibitor protein Gam
CXX11_RS24340	COG4382	Mu-like prophage protein Gp16
CXX11_RS24360	COG3460	Phenylacetate-CoA oxygenase
CXX11_RS24365	COG3396	Phenylacetate-CoA oxygenase
CXX11_RS24370	COG2151	metal-sulfur cluster biosynthetic enzyme
CXX11_RS24385	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CXX11_RS24390	COG1024	Enoyl-CoA hydratase
CXX11_RS24395	COG1024	Enoyl-CoA hydratase
CXX11_RS24400	COG1250	3-hydroxyacyl-CoA dehydrogenase
CXX11_RS24405	COG2050	protein possibly involved in aromatic compounds catabolism
CXX11_RS24410	COG0183	Belongs to the thiolase family
CXX11_RS24415	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CXX11_RS24420	COG3327	negative regulation of DNA-templated transcription, initiation
CXX11_RS24425	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CXX11_RS24455	COG0667	Aldo Keto reductase
CXX11_RS24465	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CXX11_RS24470	COG4589	Belongs to the CDS family
CXX11_RS24475	COG2267	carboxylic ester hydrolase activity
CXX11_RS24480	COG0671	phosphoesterase, PA-phosphatase related
CXX11_RS24480	COG2453	phosphatase
CXX11_RS24520	COG1396	sequence-specific DNA binding
CXX11_RS24635	COG1484	DNA-dependent DNA replication
CXX11_RS24640	COG4584	PFAM Integrase catalytic
CXX11_RS24650	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
CXX11_RS24665	COG3436	PFAM IS66 Orf2 family protein
CXX11_RS24670	COG4372	Transposase
CXX11_RS24735	COG3504	Conjugal transfer protein
CXX11_RS24865	COG3657	addiction module killer protein
CXX11_RS24955	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CXX11_RS25035	COG2826	transposase and inactivated derivatives, IS30 family
CXX11_RS25040	COG2963	transposase activity
CXX11_RS25065	COG1484	DNA-dependent DNA replication
CXX11_RS25070	COG4584	PFAM Integrase catalytic
CXX11_RS25180	COG1136	(ABC) transporter
CXX11_RS25180	COG0577	efflux transmembrane transporter activity
CXX11_RS25410	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CXX11_RS25440	COG4372	Transposase
CXX11_RS25445	COG3436	PFAM IS66 Orf2 family protein
CXX11_RS25480	COG2990	Protein conserved in bacteria
CXX11_RS25485	COG0297	glycogen (starch) synthase activity
CXX11_RS25490	COG0726	polysaccharide deacetylase
CXX11_RS25525	COG2165	general secretion pathway protein
CXX11_RS25560	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CXX11_RS25565	COG1459	type II secretion system
CXX11_RS25600	COG3436	PFAM IS66 Orf2 family protein
CXX11_RS25605	COG4372	Transposase
CXX11_RS25820	COG4372	Transposase
CXX11_RS25825	COG3436	PFAM IS66 Orf2 family protein
CXX11_RS25890	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CXX11_RS25995	COG1192	Involved in chromosome partitioning
CXX11_RS26015	COG4372	Transposase
CXX11_RS26020	COG3436	PFAM IS66 Orf2 family protein