locus-tag	class	description
CXX37_RS00155	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CXX37_RS00170	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CXX37_RS00215	COG0826	peptidase U32
CXX37_RS00225	COG0745	RESPONSE REGULATOR receiver
CXX37_RS00230	COG2205	protein histidine kinase activity
CXX37_RS00265	COG4245	von Willebrand factor, type A
CXX37_RS00270	COG0631	protein serine/threonine phosphatase activity
CXX37_RS00275	COG3779	Protein conserved in bacteria
CXX37_RS00285	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
CXX37_RS00290	COG0443	Heat shock 70 kDa protein
CXX37_RS00295	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CXX37_RS00300	COG5002	protein histidine kinase activity
CXX37_RS00300	COG5001	Diguanylate cyclase
CXX37_RS00300	COG3447	MASE1 domain protein
CXX37_RS00305	COG0572	uridine kinase
CXX37_RS00315	COG2982	Protein involved in outer membrane biogenesis
CXX37_RS00320	COG1253	flavin adenine dinucleotide binding
CXX37_RS00325	COG1596	polysaccharide export
CXX37_RS00330	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CXX37_RS00410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CXX37_RS00420	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CXX37_RS00450	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CXX37_RS00480	COG2963	transposase activity
CXX37_RS00485	COG2826	transposase and inactivated derivatives, IS30 family
CXX37_RS00540	COG3436	PFAM IS66 Orf2 family protein
CXX37_RS00545	COG4372	Transposase
CXX37_RS00555	COG3436	PFAM IS66 Orf2 family protein
CXX37_RS00615	COG3385	transposase activity
CXX37_RS00625	COG3436	PFAM IS66 Orf2 family protein
CXX37_RS00630	COG4372	Transposase
CXX37_RS00665	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CXX37_RS00670	COG0131	Imidazoleglycerol-phosphate dehydratase
CXX37_RS00670	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CXX37_RS00680	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CXX37_RS00695	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CXX37_RS00700	COG0583	DNA-binding transcription factor activity
CXX37_RS00710	COG0531	amino acid
CXX37_RS00715	COG2391	methyltransferase activity
CXX37_RS00720	COG0425	Belongs to the sulfur carrier protein TusA family
CXX37_RS00725	COG2925	Exonuclease
CXX37_RS00730	COG1686	Belongs to the peptidase S11 family
CXX37_RS00740	COG1289	transmembrane transporter activity
CXX37_RS00790	COG2003	Belongs to the UPF0758 family
CXX37_RS00905	COG3436	PFAM IS66 Orf2 family protein
CXX37_RS00910	COG4372	Transposase
CXX37_RS00950	COG4372	Transposase
CXX37_RS00955	COG3436	PFAM IS66 Orf2 family protein
CXX37_RS00990	COG1735	metal-dependent hydrolase with the TIM-barrel fold
CXX37_RS01005	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CXX37_RS01025	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
CXX37_RS01040	COG1376	ErfK ybiS ycfS ynhG family protein
CXX37_RS01050	COG0583	DNA-binding transcription factor activity
CXX37_RS01055	COG0583	DNA-binding transcription factor activity
CXX37_RS01065	COG0534	Mate efflux family protein
CXX37_RS01075	COG0217	transcriptional regulatory protein
CXX37_RS01080	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CXX37_RS01085	COG0477	Major facilitator Superfamily
CXX37_RS01115	COG3038	cytochrome b561
CXX37_RS01120	COG3443	Belongs to the bacterial solute-binding protein 9 family
CXX37_RS01135	COG2351	hydroxyisourate hydrolase activity
CXX37_RS01140	COG0745	RESPONSE REGULATOR receiver
CXX37_RS01145	COG2205	protein histidine kinase activity
CXX37_RS01160	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CXX37_RS01170	COG1418	mRNA catabolic process
CXX37_RS01175	COG0270	DNA (cytosine-5-)-methyltransferase activity
CXX37_RS01180	COG3727	T/G mismatch-specific endonuclease activity
CXX37_RS01185	COG0697	spore germination
CXX37_RS01190	COG2354	Protein conserved in bacteria
CXX37_RS01195	COG5475	Uncharacterized small protein (DUF2158)
CXX37_RS01240	COG1881	PFAM PEBP family protein
CXX37_RS01245	COG2207	Transcriptional regulator
CXX37_RS01260	COG0675	Transposase, IS605 OrfB family
CXX37_RS01265	COG2135	peptidase activity
CXX37_RS01270	COG0425	Belongs to the sulfur carrier protein TusA family
CXX37_RS01275	COG2391	methyltransferase activity
CXX37_RS01285	COG0366	Alpha amylase catalytic
CXX37_RS01295	COG1516	flagellar protein fliS
CXX37_RS01310	COG1191	sigma factor activity
CXX37_RS01320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXX37_RS01330	COG0765	amino acid transport
CXX37_RS01335	COG1126	abc transporter atp-binding protein
CXX37_RS01340	COG2197	response regulator
CXX37_RS01355	COG2197	response regulator
CXX37_RS01410	COG3385	transposase activity
CXX37_RS01415	COG3344	reverse transcriptase
CXX37_RS01435	COG2826	transposase and inactivated derivatives, IS30 family
CXX37_RS01440	COG2963	transposase activity
CXX37_RS01465	COG3318	Belongs to the UPF0149 family
CXX37_RS01465	COG3012	SEC-C Motif Domain Protein
CXX37_RS01470	COG0814	amino acid
CXX37_RS01480	COG1528	Iron-storage protein
CXX37_RS01500	COG1528	Iron-storage protein
CXX37_RS01505	COG1879	ABC-type sugar transport system periplasmic component
CXX37_RS01515	COG1172	Belongs to the binding-protein-dependent transport system permease family
CXX37_RS01520	COG1877	trehalose-phosphatase activity
CXX37_RS01530	COG0589	response to stress
CXX37_RS01545	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CXX37_RS01550	COG1360	Flagellar Motor Protein
CXX37_RS01555	COG0643	Histidine kinase
CXX37_RS01555	COG2198	Histidine kinase
CXX37_RS01560	COG0835	chemotaxis
CXX37_RS01565	COG0840	transmembrane signaling receptor activity
CXX37_RS01570	COG0840	transmembrane signaling receptor activity
CXX37_RS01575	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CXX37_RS01580	COG2201	protein-glutamate methylesterase activity
CXX37_RS01585	COG0745	RESPONSE REGULATOR receiver
CXX37_RS01590	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CXX37_RS01595	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CXX37_RS01600	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CXX37_RS01610	COG3755	Protein conserved in bacteria
CXX37_RS01620	COG3102	Protein conserved in bacteria
CXX37_RS01630	COG3005	denitrification pathway
CXX37_RS01635	COG0243	molybdopterin cofactor binding
CXX37_RS01650	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CXX37_RS01655	COG1801	Protein of unknown function DUF72
CXX37_RS01665	COG1335	isochorismatase
CXX37_RS01675	COG0494	nUDIX hydrolase
CXX37_RS01680	COG0217	transcriptional regulatory protein
CXX37_RS01720	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CXX37_RS01730	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CXX37_RS01735	COG0739	heme binding
CXX37_RS01740	COG1560	Kdo2-lipid A biosynthetic process
CXX37_RS01745	COG0469	pyruvate kinase activity
CXX37_RS01750	COG1737	Transcriptional regulator
CXX37_RS01755	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CXX37_RS01760	COG0129	dihydroxy-acid dehydratase activity
CXX37_RS01765	COG0800	Aldolase
CXX37_RS01775	COG3141	response to X-ray
CXX37_RS01785	COG2979	Protein of unknown function (DUF533)
CXX37_RS01790	COG1770	oligopeptidase
CXX37_RS01795	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CXX37_RS01800	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CXX37_RS01810	COG2372	response to copper ion
CXX37_RS01815	COG1276	copper resistance
CXX37_RS01825	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CXX37_RS01845	COG3008	intermembrane lipid transfer
CXX37_RS01850	COG2995	paraquat-inducible protein a
CXX37_RS01855	COG1956	GAF domain-containing protein
CXX37_RS01865	COG0793	Belongs to the peptidase S41A family
CXX37_RS01875	COG2814	Major facilitator Superfamily
CXX37_RS01880	COG1414	Transcriptional regulator
CXX37_RS01910	COG2226	methyltransferase
CXX37_RS01925	COG3716	PTS system mannose fructose sorbose family IID component
CXX37_RS01930	COG3715	PTS system
CXX37_RS01935	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX37_RS01935	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXX37_RS01940	COG1253	flavin adenine dinucleotide binding
CXX37_RS01945	COG2200	EAL domain
CXX37_RS01950	COG1760	l-serine dehydratase
CXX37_RS01960	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CXX37_RS01975	COG0251	oxidation-reduction process
CXX37_RS01980	COG1199	ATP-dependent helicase activity
CXX37_RS01985	COG1214	PFAM Peptidase M22, glycoprotease
CXX37_RS01990	COG3065	identical protein binding
CXX37_RS01995	COG0318	PFAM AMP-dependent synthetase and ligase
CXX37_RS02000	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CXX37_RS02005	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CXX37_RS02010	COG4638	Rieske (2fe-2S)
CXX37_RS02015	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CXX37_RS02020	COG0473	3-isopropylmalate dehydrogenase activity
CXX37_RS02025	COG0583	DNA-binding transcription factor activity
CXX37_RS02035	COG3615	Tellurite resistance protein tehB
CXX37_RS02040	COG3385	transposase activity
CXX37_RS02055	COG2261	transglycosylase associated protein
CXX37_RS02070	COG2203	Gaf domain
CXX37_RS02070	COG2199	diguanylate cyclase activity
CXX37_RS02075	COG3042	response to heat
CXX37_RS02080	COG3189	MarR family transcriptional regulator
CXX37_RS02085	COG2807	transmembrane transport
CXX37_RS02090	COG2207	Transcriptional regulator
CXX37_RS02105	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CXX37_RS02110	COG2199	diguanylate cyclase activity
CXX37_RS02115	COG2199	diguanylate cyclase activity
CXX37_RS02120	COG3039	Transposase
CXX37_RS02130	COG2766	serine protein kinase
CXX37_RS02135	COG3713	MltA-interacting MipA family protein
CXX37_RS02140	COG0656	L-ascorbic acid biosynthetic process
CXX37_RS02145	COG0676	glucose-6-phosphate 1-epimerase activity
CXX37_RS02150	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CXX37_RS02160	COG3139	Protein of unknown function (DUF1315)
CXX37_RS02165	COG1063	alcohol dehydrogenase
CXX37_RS02170	COG1063	alcohol dehydrogenase
CXX37_RS02175	COG2271	Major facilitator Superfamily
CXX37_RS02180	COG1063	alcohol dehydrogenase
CXX37_RS02185	COG0191	fructose-bisphosphate aldolase activity
CXX37_RS02190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CXX37_RS02195	COG0667	Aldo Keto reductase
CXX37_RS02200	COG1349	DNA-binding transcription factor activity
CXX37_RS02205	COG2814	Major facilitator Superfamily
CXX37_RS02210	COG1335	isochorismatase
CXX37_RS02215	COG0252	asparaginase activity
CXX37_RS02220	COG0616	signal peptide processing
CXX37_RS02225	COG0778	Nitroreductase
CXX37_RS02235	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CXX37_RS02245	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CXX37_RS02255	COG0494	nUDIX hydrolase
CXX37_RS02260	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CXX37_RS02265	COG2897	thiosulfate sulfurtransferase activity
CXX37_RS02270	COG4136	ATPase activity
CXX37_RS02275	COG4135	transport system, permease component
CXX37_RS02280	COG4134	Bacterial extracellular solute-binding protein
CXX37_RS02285	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CXX37_RS02290	COG0398	Pfam SNARE associated Golgi protein
CXX37_RS02300	COG0398	Pfam SNARE associated Golgi protein
CXX37_RS02305	COG0708	Exodeoxyribonuclease III
CXX37_RS02335	COG3678	ATP-independent chaperone mediated protein folding
CXX37_RS02345	COG0322	excinuclease ABC activity
CXX37_RS02355	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CXX37_RS02365	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CXX37_RS02370	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CXX37_RS02375	COG1447	Phosphotransferase system cellobiose-specific component IIA
CXX37_RS02380	COG2169	Transcriptional regulator
CXX37_RS02380	COG1917	Cupin 2, conserved barrel domain protein
CXX37_RS02385	COG1486	melibiose metabolic process
CXX37_RS02395	COG0753	catalase activity
CXX37_RS02415	COG1988	membrane-bound metal-dependent
CXX37_RS02420	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CXX37_RS02430	COG3001	Fructosamine kinase
CXX37_RS02440	COG1105	Belongs to the carbohydrate kinase PfkB family
CXX37_RS02450	COG3137	Salt-induced outer membrane protein
CXX37_RS02495	COG0072	phenylalanine-tRNA ligase activity
CXX37_RS02495	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CXX37_RS02510	COG0386	Belongs to the glutathione peroxidase family
CXX37_RS02520	COG0791	NLP P60 protein
CXX37_RS02525	COG2200	EAL domain
CXX37_RS02535	COG4256	Hemin uptake protein
CXX37_RS02540	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CXX37_RS02550	COG0574	Belongs to the PEP-utilizing enzyme family
CXX37_RS02550	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CXX37_RS02555	COG0318	PFAM AMP-dependent synthetase and ligase
CXX37_RS02560	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CXX37_RS02565	COG0644	oxidoreductase
CXX37_RS02570	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CXX37_RS02575	COG2086	electron transfer activity
CXX37_RS02585	COG1960	acyl-CoA dehydrogenase activity
CXX37_RS02590	COG4670	ketone body catabolic process
CXX37_RS02605	COG2271	Major facilitator Superfamily
CXX37_RS02610	COG0738	Major facilitator superfamily
CXX37_RS02625	COG0628	permease
CXX37_RS02630	COG0277	FAD linked oxidase domain protein
CXX37_RS02630	COG0247	lactate metabolic process
CXX37_RS02635	COG2050	protein possibly involved in aromatic compounds catabolism
CXX37_RS02645	COG0316	Belongs to the HesB IscA family
CXX37_RS02650	COG0719	Fe-S assembly protein
CXX37_RS02655	COG0396	ATPase activity
CXX37_RS02660	COG0719	Fe-S assembly protein
CXX37_RS02675	COG1376	ErfK ybiS ycfS ynhG family protein
CXX37_RS02680	COG4238	major outer membrane lipoprotein
CXX37_RS02685	COG0469	pyruvate kinase activity
CXX37_RS02695	COG0437	4 iron, 4 sulfur cluster binding
CXX37_RS02700	COG2414	aldehyde ferredoxin oxidoreductase
CXX37_RS02710	COG0437	4 iron, 4 sulfur cluster binding
CXX37_RS02715	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
CXX37_RS02725	COG4529	Protein conserved in bacteria
CXX37_RS02745	COG3468	outer membrane autotransporter barrel domain protein
CXX37_RS02755	COG0307	riboflavin synthase, alpha
CXX37_RS02760	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CXX37_RS02765	COG2814	Major facilitator Superfamily
CXX37_RS02770	COG0583	DNA-binding transcription factor activity
CXX37_RS02785	COG2814	Major facilitator Superfamily
CXX37_RS02790	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CXX37_RS02795	COG0791	NLP P60 protein
CXX37_RS02800	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CXX37_RS02805	COG1201	RNA secondary structure unwinding
CXX37_RS02810	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CXX37_RS02815	COG0346	lactoylglutathione lyase activity
CXX37_RS02820	COG1902	pentaerythritol trinitrate reductase activity
CXX37_RS02825	COG1309	transcriptional regulator
CXX37_RS02830	COG3313	Fe-S protein
CXX37_RS02835	COG4989	oxidoreductase activity
CXX37_RS02840	COG2032	superoxide dismutase activity
CXX37_RS02845	COG1289	transmembrane transporter activity
CXX37_RS02850	COG1566	PFAM secretion protein HlyD family protein
CXX37_RS02865	COG3133	Outer membrane lipoprotein
CXX37_RS02875	COG3895	Periplasmic Protein
CXX37_RS02890	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CXX37_RS02895	COG0625	glutathione transferase activity
CXX37_RS02900	COG3104	oligopeptide transport
CXX37_RS02905	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CXX37_RS02915	COG4659	FMN binding
CXX37_RS02955	COG0673	inositol 2-dehydrogenase activity
CXX37_RS02965	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CXX37_RS02970	COG1263	PTS System
CXX37_RS02970	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXX37_RS02975	COG1609	Transcriptional regulator
CXX37_RS02980	COG1028	Short-chain dehydrogenase reductase Sdr
CXX37_RS02985	COG1309	transcriptional regulator
CXX37_RS02990	COG3250	beta-galactosidase activity
CXX37_RS03005	COG5339	Protein conserved in bacteria
CXX37_RS03010	COG1482	cell wall glycoprotein biosynthetic process
CXX37_RS03015	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CXX37_RS03015	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CXX37_RS03020	COG0114	fumarate hydratase activity
CXX37_RS03030	COG2205	protein histidine kinase activity
CXX37_RS03035	COG0745	RESPONSE REGULATOR receiver
CXX37_RS03040	COG3136	membrane protein required for alginate biosynthesis
CXX37_RS03050	COG0531	amino acid
CXX37_RS03060	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CXX37_RS03065	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CXX37_RS03070	COG0628	permease
CXX37_RS03090	COG3591	Belongs to the peptidase S1B family
CXX37_RS03105	COG2814	Major facilitator Superfamily
CXX37_RS03110	COG0583	DNA-binding transcription factor activity
CXX37_RS03115	COG1940	carbohydrate kinase activity
CXX37_RS03120	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CXX37_RS03130	COG3381	protein complex oligomerization
CXX37_RS03135	COG3302	dmso reductase anchor subunit
CXX37_RS03140	COG0437	4 iron, 4 sulfur cluster binding
CXX37_RS03145	COG0243	molybdopterin cofactor binding
CXX37_RS03165	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CXX37_RS03180	COG4948	Mandelate Racemase Muconate Lactonizing
CXX37_RS03185	COG1063	alcohol dehydrogenase
CXX37_RS03195	COG0582	viral genome integration into host DNA
CXX37_RS03205	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CXX37_RS03240	COG1396	sequence-specific DNA binding
CXX37_RS03255	COG1846	Transcriptional regulator
CXX37_RS03300	COG1403	HNH endonuclease
CXX37_RS03305	COG0484	heat shock protein binding
CXX37_RS03315	COG1278	Cold shock
CXX37_RS03320	COG1278	Cold shock
CXX37_RS03345	COG1278	Cold shock
CXX37_RS03375	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CXX37_RS03380	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CXX37_RS03400	COG0477	Major facilitator Superfamily
CXX37_RS03410	COG0246	Mannitol dehydrogenase
CXX37_RS03420	COG1802	Transcriptional regulator
CXX37_RS03425	COG4221	oxidoreductase activity
CXX37_RS03430	COG0339	signal peptide processing
CXX37_RS03435	COG1546	Belongs to the CinA family
CXX37_RS03440	COG3111	PFAM Bacterial OB fold (BOF) protein
CXX37_RS03445	COG3706	GGDEF domain
CXX37_RS03455	COG2814	Major facilitator Superfamily
CXX37_RS03460	COG0697	spore germination
CXX37_RS03470	COG4977	sequence-specific DNA binding
CXX37_RS03475	COG1846	Transcriptional regulator
CXX37_RS03495	COG0583	DNA-binding transcription factor activity
CXX37_RS03500	COG1012	belongs to the aldehyde dehydrogenase family
CXX37_RS03505	COG2066	Belongs to the glutaminase family
CXX37_RS03515	COG2199	diguanylate cyclase activity
CXX37_RS03525	COG3781	membrane
CXX37_RS03535	COG3385	transposase activity
CXX37_RS03580	COG3210	domain, Protein
CXX37_RS03580	COG2911	Protein conserved in bacteria
CXX37_RS03585	COG1396	sequence-specific DNA binding
CXX37_RS03590	COG3550	peptidyl-serine autophosphorylation
CXX37_RS03610	COG3539	Fimbrial protein
CXX37_RS03615	COG3539	Fimbrial protein
CXX37_RS03620	COG0243	molybdopterin cofactor binding
CXX37_RS03635	COG3119	arylsulfatase activity
CXX37_RS03640	COG0641	radical SAM
CXX37_RS03650	COG4178	(ABC) transporter
CXX37_RS03655	COG4771	TonB-dependent receptor
CXX37_RS03660	COG0612	Peptidase, M16
CXX37_RS03675	COG0076	glutamate decarboxylase activity
CXX37_RS03680	COG0531	amino acid
CXX37_RS03685	COG1649	PFAM Uncharacterised BCR, COG1649
CXX37_RS03690	COG3706	GGDEF domain
CXX37_RS03695	COG2199	diguanylate cyclase activity
CXX37_RS03695	COG2202	Pas domain
CXX37_RS03695	COG2200	EAL domain
CXX37_RS03705	COG0747	negative chemotaxis
CXX37_RS03710	COG0601	transmembrane transport
CXX37_RS03715	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CXX37_RS03720	COG0444	Belongs to the ABC transporter superfamily
CXX37_RS03725	COG4608	Belongs to the ABC transporter superfamily
CXX37_RS03730	COG1764	response to oxidative stress
CXX37_RS03750	COG1064	alcohol dehydrogenase
CXX37_RS03755	COG3093	addiction module antidote protein HigA
CXX37_RS03760	COG2864	formate dehydrogenase
CXX37_RS03765	COG0437	4 iron, 4 sulfur cluster binding
CXX37_RS03775	COG0697	spore germination
CXX37_RS03780	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CXX37_RS03785	COG4886	Leucine-rich repeat (LRR) protein
CXX37_RS03790	COG4886	Leucine-rich repeat (LRR) protein
CXX37_RS03800	COG2223	nitrite transmembrane transporter activity
CXX37_RS03805	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CXX37_RS03810	COG1140	nitrate reductase beta subunit
CXX37_RS03815	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CXX37_RS03820	COG2181	nitrate reductase activity
CXX37_RS03825	COG0384	phenazine biosynthesis protein PhzF
CXX37_RS03830	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CXX37_RS03835	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CXX37_RS03845	COG5433	transposase activity
CXX37_RS03865	COG3209	COG3209 Rhs family protein
CXX37_RS03880	COG0625	glutathione transferase activity
CXX37_RS03885	COG1113	amino acid transport
CXX37_RS03890	COG3391	amine dehydrogenase activity
CXX37_RS03895	COG4772	TonB-dependent receptor
CXX37_RS03900	COG1802	Transcriptional regulator
CXX37_RS03905	COG2130	NADP-dependent
CXX37_RS03910	COG1247	-acetyltransferase
CXX37_RS03915	COG3238	Protein conserved in bacteria
CXX37_RS03940	COG1177	transmembrane transport
CXX37_RS03945	COG1176	ABC-type spermidine putrescine transport system, permease component I
CXX37_RS03950	COG3842	ATPase activity
CXX37_RS03955	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CXX37_RS03960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CXX37_RS03965	COG1598	PFAM Uncharacterised protein family UPF0150
CXX37_RS03970	COG1724	mRNA binding
CXX37_RS03980	COG0826	peptidase U32
CXX37_RS03985	COG1396	sequence-specific DNA binding
CXX37_RS03990	COG3135	benzoate transporter
CXX37_RS03995	COG0675	Transposase, IS605 OrfB family
CXX37_RS04010	COG0500	methyltransferase
CXX37_RS04015	COG1275	C4-dicarboxylate transporter malic acid transport protein
CXX37_RS04020	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CXX37_RS04025	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CXX37_RS04030	COG2841	Protein conserved in bacteria
CXX37_RS04040	COG5383	Protein conserved in bacteria
CXX37_RS04045	COG0583	DNA-binding transcription factor activity
CXX37_RS04050	COG0840	transmembrane signaling receptor activity
CXX37_RS04070	COG3038	cytochrome b561
CXX37_RS04080	COG1012	belongs to the aldehyde dehydrogenase family
CXX37_RS04090	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CXX37_RS04095	COG1643	Atp-dependent helicase
CXX37_RS04105	COG2453	phosphatase
CXX37_RS04105	COG0671	phosphoesterase, PA-phosphatase related
CXX37_RS04110	COG2267	carboxylic ester hydrolase activity
CXX37_RS04125	COG3733	amine oxidase
CXX37_RS04130	COG1012	belongs to the aldehyde dehydrogenase family
CXX37_RS04135	COG2207	Transcriptional regulator
CXX37_RS04140	COG3784	Protein of unknown function (DUF1318)
CXX37_RS04150	COG2911	Protein conserved in bacteria
CXX37_RS04155	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CXX37_RS04160	COG3187	Heat shock protein
CXX37_RS04165	COG3042	response to heat
CXX37_RS04170	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CXX37_RS04170	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CXX37_RS04170	COG1013	pyruvate-flavodoxin oxidoreductase activity
CXX37_RS04170	COG0674	pyruvate-flavodoxin oxidoreductase activity
CXX37_RS04175	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CXX37_RS04180	COG0589	response to stress
CXX37_RS04190	COG0513	Belongs to the DEAD box helicase family
CXX37_RS04200	COG3706	GGDEF domain
CXX37_RS04205	COG2840	Smr protein MutS2
CXX37_RS04210	COG0583	DNA-binding transcription factor activity
CXX37_RS04215	COG1473	amidohydrolase
CXX37_RS04220	COG1473	amidohydrolase
CXX37_RS04225	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CXX37_RS04230	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CXX37_RS04235	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CXX37_RS04240	COG0589	response to stress
CXX37_RS04245	COG3182	Iron-regulated membrane protein
CXX37_RS04250	COG0668	transmembrane transport
CXX37_RS04255	COG4166	transmembrane transport
CXX37_RS04260	COG0583	DNA-binding transcription factor activity
CXX37_RS04265	COG1073	alpha beta
CXX37_RS04280	COG2866	Carboxypeptidase
CXX37_RS04285	COG4948	Mandelate Racemase Muconate Lactonizing
CXX37_RS04290	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CXX37_RS04295	COG3283	Transcriptional regulator of aromatic amino acids metabolism
CXX37_RS04305	COG3106	COG3106 Predicted ATPase
CXX37_RS04310	COG1609	Transcriptional regulator
CXX37_RS04320	COG3842	ATPase activity
CXX37_RS04325	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CXX37_RS04330	COG1554	hydrolase, family 65, central catalytic
CXX37_RS04335	COG0673	inositol 2-dehydrogenase activity
CXX37_RS04340	COG1082	Xylose isomerase domain protein TIM barrel
CXX37_RS04345	COG1063	alcohol dehydrogenase
CXX37_RS04350	COG0395	ABC-type sugar transport system, permease component
CXX37_RS04360	COG1653	transport
CXX37_RS04370	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CXX37_RS04380	COG1983	PspC domain protein
CXX37_RS04390	COG1842	Phage shock protein A
CXX37_RS04395	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CXX37_RS04400	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CXX37_RS04405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CXX37_RS04410	COG1012	belongs to the aldehyde dehydrogenase family
CXX37_RS04415	COG1917	Cupin 2, conserved barrel domain protein
CXX37_RS04415	COG1396	sequence-specific DNA binding
CXX37_RS04420	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CXX37_RS04425	COG0174	glutamine synthetase
CXX37_RS04435	COG0531	amino acid
CXX37_RS04445	COG4166	transmembrane transport
CXX37_RS04450	COG4168	peptide transport system, permease
CXX37_RS04455	COG4171	peptide transport system, permease
CXX37_RS04460	COG4172	Belongs to the ABC transporter superfamily
CXX37_RS04465	COG4172	Belongs to the ABC transporter superfamily
CXX37_RS04470	COG2852	Protein conserved in bacteria
CXX37_RS04475	COG3385	transposase activity
CXX37_RS04480	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CXX37_RS04485	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CXX37_RS04485	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CXX37_RS04500	COG5001	Diguanylate cyclase
CXX37_RS04510	COG1349	DNA-binding transcription factor activity
CXX37_RS04520	COG0023	Translation Initiation Factor
CXX37_RS04530	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CXX37_RS04535	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CXX37_RS04540	COG0671	phosphoesterase, PA-phosphatase related
CXX37_RS04550	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CXX37_RS04570	COG0583	DNA-binding transcription factor activity
CXX37_RS04575	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CXX37_RS04585	COG0616	signal peptide processing
CXX37_RS04590	COG1028	Short-chain dehydrogenase reductase Sdr
CXX37_RS04595	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CXX37_RS04600	COG1187	pseudouridine synthase activity
CXX37_RS04605	COG4907	membrane protein (DUF2207)
CXX37_RS04610	COG0009	L-threonylcarbamoyladenylate synthase
CXX37_RS04615	COG0613	PHP domain protein
CXX37_RS04625	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CXX37_RS04630	COG0512	Glutamine amidotransferase of anthranilate synthase
CXX37_RS04630	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CXX37_RS04635	COG0134	indole-3-glycerol-phosphate synthase activity
CXX37_RS04635	COG0135	phosphoribosylanthranilate isomerase activity
CXX37_RS04650	COG3729	General stress protein
CXX37_RS04655	COG3685	Protein conserved in bacteria
CXX37_RS04660	COG3685	Protein conserved in bacteria
CXX37_RS04665	COG3047	cAMP biosynthetic process
CXX37_RS04685	COG1607	acyl-coa hydrolase
CXX37_RS04690	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CXX37_RS04695	COG2350	Protein conserved in bacteria
CXX37_RS04700	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CXX37_RS04720	COG4608	Belongs to the ABC transporter superfamily
CXX37_RS04725	COG0444	Belongs to the ABC transporter superfamily
CXX37_RS04730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CXX37_RS04735	COG0601	transmembrane transport
CXX37_RS04740	COG4166	transmembrane transport
CXX37_RS04745	COG2095	MarC family integral membrane protein
CXX37_RS04750	COG1012	belongs to the aldehyde dehydrogenase family
CXX37_RS04750	COG1454	alcohol dehydrogenase
CXX37_RS04760	COG1435	thymidine kinase activity
CXX37_RS04770	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CXX37_RS04775	COG0745	RESPONSE REGULATOR receiver
CXX37_RS04780	COG1752	Esterase of the alpha-beta hydrolase superfamily
CXX37_RS04790	COG0788	formyltetrahydrofolate deformylase activity
CXX37_RS04820	COG2181	nitrate reductase activity
CXX37_RS04825	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CXX37_RS04830	COG1140	nitrate reductase beta subunit
CXX37_RS04835	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CXX37_RS04840	COG2223	nitrite transmembrane transporter activity
CXX37_RS04845	COG3850	Histidine kinase
CXX37_RS04850	COG2197	response regulator
CXX37_RS04855	COG4932	domain protein
CXX37_RS04860	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CXX37_RS04865	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CXX37_RS04870	COG4572	Cation transport regulator
CXX37_RS04875	COG0387	Pfam Sodium calcium exchanger
CXX37_RS04905	COG2912	Transglutaminase-like superfamily
CXX37_RS04910	COG3094	Invasion gene expression up-regulator, SirB
CXX37_RS04915	COG2890	protein-(glutamine-N5) methyltransferase activity
CXX37_RS04940	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CXX37_RS04945	COG0659	secondary active sulfate transmembrane transporter activity
CXX37_RS04960	COG0012	GTP binding
CXX37_RS04965	COG3468	outer membrane autotransporter barrel domain protein
CXX37_RS04970	COG3284	Transcriptional regulator
CXX37_RS04975	COG2376	Dihydroxyacetone kinase
CXX37_RS04980	COG1461	Dihydroxyacetone kinase
CXX37_RS04985	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CXX37_RS04985	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX37_RS04985	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CXX37_RS05000	COG2261	transglycosylase associated protein
CXX37_RS05005	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CXX37_RS05015	COG1619	proteins homologs of microcin C7 resistance protein MccF
CXX37_RS05025	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CXX37_RS05035	COG2719	SpoVR family
CXX37_RS05050	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CXX37_RS05055	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CXX37_RS05060	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CXX37_RS05075	COG0179	Fumarylacetoacetate (FAA) hydrolase
CXX37_RS05100	COG2894	cell division
CXX37_RS05170	COG2200	EAL domain
CXX37_RS05195	COG2200	EAL domain
CXX37_RS05200	COG0789	Transcriptional regulator
CXX37_RS05205	COG5562	phage envelope protein
CXX37_RS05220	COG0538	isocitrate dehydrogenase activity
CXX37_RS05225	COG1187	pseudouridine synthase activity
CXX37_RS05245	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CXX37_RS05250	COG0745	RESPONSE REGULATOR receiver
CXX37_RS05255	COG2205	protein histidine kinase activity
CXX37_RS05260	COG2850	peptidyl-arginine hydroxylation
CXX37_RS05270	COG3842	ATPase activity
CXX37_RS05285	COG0500	methyltransferase
CXX37_RS05295	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CXX37_RS05300	COG5301	cellulose 1,4-beta-cellobiosidase activity
CXX37_RS05335	COG1196	nuclear chromosome segregation
CXX37_RS05385	COG1030	water channel activity
CXX37_RS05405	COG4220	transposase activity
CXX37_RS05490	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CXX37_RS05495	COG1403	HNH endonuclease
CXX37_RS05540	COG1846	Transcriptional regulator
CXX37_RS05545	COG1484	DNA-dependent DNA replication
CXX37_RS05550	COG1846	Transcriptional regulator
CXX37_RS05600	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CXX37_RS05610	COG0582	viral genome integration into host DNA
CXX37_RS05625	COG1177	transmembrane transport
CXX37_RS05630	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CXX37_RS05640	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CXX37_RS05645	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CXX37_RS05655	COG4591	ABC-type transport system involved in lipoprotein release permease component
CXX37_RS05660	COG1136	(ABC) transporter
CXX37_RS05665	COG4591	ABC-type transport system involved in lipoprotein release permease component
CXX37_RS05670	COG4763	Acyl-transferase
CXX37_RS05675	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CXX37_RS05680	COG1388	LysM domain
CXX37_RS05680	COG1376	ErfK ybiS ycfS ynhG family protein
CXX37_RS05690	COG1309	transcriptional regulator
CXX37_RS05695	COG3134	Outer membrane lipoprotein
CXX37_RS05700	COG1252	NADH dehydrogenase
CXX37_RS05720	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
CXX37_RS05725	COG5633	Lipoprotein
CXX37_RS05730	COG0537	adenosine 5'-monophosphoramidase activity
CXX37_RS05735	COG4773	Receptor
CXX37_RS05740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXX37_RS05740	COG1263	PTS System
CXX37_RS05745	COG0084	hydrolase, TatD family'
CXX37_RS05750	COG0470	DNA polymerase III
CXX37_RS05760	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CXX37_RS05765	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CXX37_RS05770	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CXX37_RS05780	COG1028	Short-chain dehydrogenase reductase Sdr
CXX37_RS05785	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CXX37_RS05805	COG1399	metal-binding, possibly nucleic acid-binding protein
CXX37_RS05810	COG0424	maF-like protein
CXX37_RS05815	COG0564	pseudouridine synthase activity
CXX37_RS05825	COG1530	ribonuclease E activity
CXX37_RS05835	COG1256	bacterial-type flagellum assembly
CXX37_RS05840	COG3951	Flagellar rod assembly protein muramidase FlgJ
CXX37_RS05840	COG1705	Flagellar rod assembly protein muramidase FlgJ
CXX37_RS05855	COG4786	Flagellar basal body rod
CXX37_RS05860	COG4787	bacterial-type flagellum-dependent cell motility
CXX37_RS05865	COG1749	Flagellar hook protein flgE
CXX37_RS05870	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CXX37_RS05875	COG1558	bacterial-type flagellum-dependent cell motility
CXX37_RS05880	COG1815	bacterial-type flagellum-dependent cell motility
CXX37_RS05885	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
CXX37_RS05890	COG2747	anti-sigma28 factor FlgM
CXX37_RS05895	COG3418	PFAM FlgN family protein
CXX37_RS05900	COG0728	peptidoglycan biosynthetic process
CXX37_RS05905	COG0673	inositol 2-dehydrogenase activity
CXX37_RS05915	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CXX37_RS05925	COG2999	glutathione oxidoreductase activity
CXX37_RS05960	COG3038	cytochrome b561
CXX37_RS05965	COG2353	YceI-like domain
CXX37_RS05975	COG1560	Kdo2-lipid A biosynthetic process
CXX37_RS05990	COG5645	(Lipo)protein
CXX37_RS05995	COG2943	transferase activity, transferring hexosyl groups
CXX37_RS06010	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CXX37_RS06015	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CXX37_RS06040	COG2197	response regulator
CXX37_RS06055	COG1462	curli production assembly transport component CsgG
CXX37_RS06065	COG3381	protein complex oligomerization
CXX37_RS06105	COG3706	GGDEF domain
CXX37_RS06110	COG0457	Tetratricopeptide repeat
CXX37_RS06115	COG1649	PFAM Uncharacterised BCR, COG1649
CXX37_RS06115	COG0726	polysaccharide deacetylase
CXX37_RS06120	COG1215	transferase activity, transferring glycosyl groups
CXX37_RS06125	COG3658	cytochrome
CXX37_RS06130	COG1702	phosphate starvation-inducible protein PhoH
CXX37_RS06135	COG2837	iron assimilation
CXX37_RS06140	COG2822	iron ion transport
CXX37_RS06150	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CXX37_RS06160	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CXX37_RS06160	COG0506	proline dehydrogenase activity
CXX37_RS06160	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CXX37_RS06165	COG1309	transcriptional regulator
CXX37_RS06205	COG2233	PERMEase
CXX37_RS06210	COG3729	General stress protein
CXX37_RS06245	COG3381	protein complex oligomerization
CXX37_RS06250	COG0243	molybdopterin cofactor binding
CXX37_RS06255	COG3005	denitrification pathway
CXX37_RS06260	COG0745	RESPONSE REGULATOR receiver
CXX37_RS06265	COG1879	ABC-type sugar transport system periplasmic component
CXX37_RS06270	COG2198	Histidine kinase
CXX37_RS06270	COG2205	protein histidine kinase activity
CXX37_RS06270	COG0784	Response regulator, receiver
CXX37_RS06275	COG0348	domain, Protein
CXX37_RS06295	COG1278	Cold shock
CXX37_RS06300	COG1278	Cold shock
CXX37_RS06320	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CXX37_RS06325	COG1596	polysaccharide export
CXX37_RS06330	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CXX37_RS06335	COG0489	protein tyrosine kinase activity
CXX37_RS06335	COG3206	protein involved in exopolysaccharide biosynthesis
CXX37_RS06350	COG1294	oxidase, subunit
CXX37_RS06355	COG1271	oxidase subunit
CXX37_RS06360	COG1773	rubredoxin
CXX37_RS06365	COG1999	signal sequence binding
CXX37_RS06370	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CXX37_RS06375	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
CXX37_RS06380	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CXX37_RS06385	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CXX37_RS06395	COG0670	Belongs to the BI1 family
CXX37_RS06400	COG2920	part of a sulfur-relay system
CXX37_RS06405	COG1254	Belongs to the acylphosphatase family
CXX37_RS06420	COG1832	CoA-binding protein
CXX37_RS06435	COG0210	DNA helicase
CXX37_RS06440	COG3304	Inner membrane component domain
CXX37_RS06445	COG1289	transmembrane transporter activity
CXX37_RS06450	COG3070	regulator of competence-specific genes
CXX37_RS06460	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CXX37_RS06460	COG2885	chlorophyll binding
CXX37_RS06470	COG1067	ATP-dependent peptidase activity
CXX37_RS06480	COG3130	regulation of translation
CXX37_RS06485	COG3009	Protein conserved in bacteria
CXX37_RS06490	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CXX37_RS06490	COG3008	intermembrane lipid transfer
CXX37_RS06495	COG2995	paraquat-inducible protein a
CXX37_RS06500	COG0488	(ABC) transporter
CXX37_RS06510	COG3217	Mosc domain protein beta barrel domain protein
CXX37_RS06510	COG0633	Ferredoxin
CXX37_RS06525	COG3121	Chaperone
CXX37_RS06530	COG3539	Fimbrial protein
CXX37_RS06535	COG3539	Fimbrial protein
CXX37_RS06540	COG3539	Fimbrial protein
CXX37_RS06550	COG3121	Chaperone
CXX37_RS06555	COG3539	Fimbrial protein
CXX37_RS06560	COG0431	NADPH-dependent FMN reductase
CXX37_RS06565	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CXX37_RS06575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CXX37_RS06580	COG1116	anion transmembrane transporter activity
CXX37_RS06585	COG0308	aminopeptidase N
CXX37_RS06605	COG1448	Aminotransferase
CXX37_RS06610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CXX37_RS06615	COG3108	Peptidase M15
CXX37_RS06620	COG2989	Protein conserved in bacteria
CXX37_RS06630	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CXX37_RS06640	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CXX37_RS06645	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CXX37_RS06650	COG3173	Aminoglycoside phosphotransferase
CXX37_RS06665	COG3214	Protein conserved in bacteria
CXX37_RS06670	COG1663	tetraacyldisaccharide 4'-kinase activity
CXX37_RS06675	COG1132	(ABC) transporter
CXX37_RS06680	COG0658	competence protein
CXX37_RS06680	COG2333	competence protein COMEC
CXX37_RS06690	COG0539	negative regulation of cytoplasmic translation
CXX37_RS06700	COG0501	Belongs to the peptidase M48B family
CXX37_RS06715	COG2323	membrane
CXX37_RS06720	COG1944	ATP diphosphatase activity
CXX37_RS06725	COG2116	formate transmembrane transporter activity
CXX37_RS06730	COG1882	Formate acetyltransferase
CXX37_RS06735	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CXX37_RS06740	COG2249	NAD(P)H dehydrogenase (quinone) activity
CXX37_RS06745	COG0583	DNA-binding transcription factor activity
CXX37_RS06750	COG0531	amino acid
CXX37_RS06760	COG1335	isochorismatase
CXX37_RS06765	COG3385	transposase activity
CXX37_RS06770	COG3302	dmso reductase anchor subunit
CXX37_RS06775	COG0437	4 iron, 4 sulfur cluster binding
CXX37_RS06780	COG0243	molybdopterin cofactor binding
CXX37_RS06785	COG4974	Belongs to the 'phage' integrase family
CXX37_RS06885	COG4695	Portal protein
CXX37_RS06965	COG5301	cellulose 1,4-beta-cellobiosidase activity
CXX37_RS06985	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CXX37_RS06995	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CXX37_RS07005	COG2848	UPF0210 protein
CXX37_RS07050	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CXX37_RS07060	COG1178	ABC-type Fe3 transport system permease component
CXX37_RS07060	COG1674	ftsk spoiiie
CXX37_RS07065	COG1522	sequence-specific DNA binding
CXX37_RS07070	COG0492	ferredoxin-NADP+ reductase activity
CXX37_RS07075	COG4988	ABC transporter
CXX37_RS07080	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CXX37_RS07105	COG0542	response to heat
CXX37_RS07115	COG1278	Cold shock
CXX37_RS07120	COG1136	(ABC) transporter
CXX37_RS07120	COG0577	efflux transmembrane transporter activity
CXX37_RS07125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CXX37_RS07130	COG2990	Protein conserved in bacteria
CXX37_RS07135	COG3593	DNA synthesis involved in DNA repair
CXX37_RS07145	COG2431	L-lysine efflux transmembrane transporter activity
CXX37_RS07155	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CXX37_RS07160	COG0028	Belongs to the TPP enzyme family
CXX37_RS07165	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CXX37_RS07170	COG0702	epimerase
CXX37_RS07175	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CXX37_RS07180	COG3023	N-Acetylmuramoyl-L-alanine amidase
CXX37_RS07195	COG1126	abc transporter atp-binding protein
CXX37_RS07200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXX37_RS07205	COG4215	(ABC) transporter
CXX37_RS07210	COG4160	amino acid transport
CXX37_RS07215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXX37_RS07230	COG1177	transmembrane transport
CXX37_RS07235	COG1176	ABC-type spermidine putrescine transport system, permease component I
CXX37_RS07240	COG3842	ATPase activity
CXX37_RS07245	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CXX37_RS07260	COG0778	Nitroreductase
CXX37_RS07270	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CXX37_RS07285	COG3226	Transcriptional regulator
CXX37_RS07290	COG0738	Major facilitator superfamily
CXX37_RS07295	COG0561	phosphatase activity
CXX37_RS07305	COG2814	Major facilitator Superfamily
CXX37_RS07310	COG0671	phosphoesterase, PA-phosphatase related
CXX37_RS07315	COG1349	DNA-binding transcription factor activity
CXX37_RS07320	COG1686	Belongs to the peptidase S11 family
CXX37_RS07325	COG0625	glutathione transferase activity
CXX37_RS07330	COG2133	pyrroloquinoline quinone binding
CXX37_RS07345	COG2199	diguanylate cyclase activity
CXX37_RS07350	COG2200	EAL domain
CXX37_RS07355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CXX37_RS07365	COG0747	negative chemotaxis
CXX37_RS07370	COG4172	Belongs to the ABC transporter superfamily
CXX37_RS07375	COG1446	asparaginase
CXX37_RS07380	COG0303	'Molybdopterin
CXX37_RS07385	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CXX37_RS07390	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CXX37_RS07395	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CXX37_RS07400	COG1882	Formate acetyltransferase
CXX37_RS07405	COG0561	phosphatase activity
CXX37_RS07415	COG0488	(ABC) transporter
CXX37_RS07420	COG1376	ErfK ybiS ycfS ynhG family protein
CXX37_RS07425	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CXX37_RS07430	COG1321	iron dependent repressor
CXX37_RS07440	COG2194	sulfuric ester hydrolase activity
CXX37_RS07445	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CXX37_RS07455	COG5006	permease, DMT superfamily
CXX37_RS07465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXX37_RS07470	COG0765	amino acid transport
CXX37_RS07475	COG1126	abc transporter atp-binding protein
CXX37_RS07480	COG0668	transmembrane transport
CXX37_RS07495	COG4774	siderophore transport
CXX37_RS07505	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CXX37_RS07515	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CXX37_RS07520	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CXX37_RS07525	COG1199	ATP-dependent helicase activity
CXX37_RS07530	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
CXX37_RS07535	COG0513	Belongs to the DEAD box helicase family
CXX37_RS07540	COG1309	transcriptional regulator
CXX37_RS07550	COG1131	(ABC) transporter
CXX37_RS07555	COG0842	Transport permease protein
CXX37_RS07560	COG0842	Transport permease protein
CXX37_RS07570	COG3568	Endonuclease Exonuclease Phosphatase
CXX37_RS07575	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CXX37_RS07580	COG0392	lysyltransferase activity
CXX37_RS07585	COG0670	Belongs to the BI1 family
CXX37_RS07590	COG0670	Belongs to the BI1 family
CXX37_RS07595	COG0314	molybdopterin synthase activity
CXX37_RS07600	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CXX37_RS07610	COG0521	Mo-molybdopterin cofactor biosynthetic process
CXX37_RS07620	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CXX37_RS07630	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CXX37_RS07635	COG2226	methyltransferase
CXX37_RS07650	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CXX37_RS07655	COG1881	PFAM PEBP family protein
CXX37_RS07805	COG3561	AntA/AntB antirepressor
CXX37_RS07815	COG0582	viral genome integration into host DNA
CXX37_RS07820	COG4677	pectinesterase activity
CXX37_RS07825	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CXX37_RS07830	COG0471	metal ion transport
CXX37_RS07835	COG2828	Protein conserved in bacteria
CXX37_RS07840	COG0583	DNA-binding transcription factor activity
CXX37_RS07850	COG0561	phosphatase activity
CXX37_RS07855	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CXX37_RS07860	COG4149	molybdate abc transporter
CXX37_RS07865	COG0725	ABC transporter, periplasmic molybdate-binding protein
CXX37_RS07875	COG3585	molybdate ion transport
CXX37_RS07875	COG2005	Transcriptional regulator
CXX37_RS07880	COG1119	ATPase activity
CXX37_RS07885	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CXX37_RS07890	COG1085	galactose-1-phosphate uridylyltransferase
CXX37_RS07900	COG2017	converts alpha-aldose to the beta-anomer
CXX37_RS07910	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CXX37_RS07920	COG1230	cation diffusion facilitator family transporter
CXX37_RS07925	COG3201	nicotinamide mononucleotide transporter
CXX37_RS07970	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CXX37_RS07975	COG2885	chlorophyll binding
CXX37_RS07985	COG3064	Membrane
CXX37_RS07990	COG0848	biopolymer transport protein
CXX37_RS07995	COG0811	peptide transport
CXX37_RS08000	COG0824	Thioesterase
CXX37_RS08005	COG3790	cyd operon protein YbgE
CXX37_RS08010	COG4890	Cyd operon protein YbgT
CXX37_RS08015	COG1294	oxidase, subunit
CXX37_RS08020	COG1271	oxidase subunit
CXX37_RS08025	COG0383	alpha-mannosidase activity
CXX37_RS08035	COG2188	Transcriptional regulator
CXX37_RS08040	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CXX37_RS08050	COG0508	dehydrogenase complex catalyzes the overall conversion of
CXX37_RS08055	COG0567	Dehydrogenase, E1 component
CXX37_RS08060	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CXX37_RS08065	COG1053	succinate dehydrogenase
CXX37_RS08070	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CXX37_RS08075	COG2009	succinate dehydrogenase
CXX37_RS08085	COG0372	Belongs to the citrate synthase family
CXX37_RS08090	COG3539	Fimbrial protein
CXX37_RS08095	COG3188	usher protein
CXX37_RS08100	COG3121	Chaperone
CXX37_RS08105	COG3539	Fimbrial protein
CXX37_RS08110	COG3180	Ammonia monooxygenase
CXX37_RS08125	COG1984	allophanate hydrolase subunit 2
CXX37_RS08130	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CXX37_RS08135	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CXX37_RS08140	COG3104	oligopeptide transport
CXX37_RS08145	COG0415	Belongs to the DNA photolyase family
CXX37_RS08150	COG3272	Protein of unknown function (DUF1722)
CXX37_RS08175	COG2223	nitrite transmembrane transporter activity
CXX37_RS08180	COG1070	Carbohydrate kinase
CXX37_RS08205	COG3209	COG3209 Rhs family protein
CXX37_RS08235	COG2205	protein histidine kinase activity
CXX37_RS08240	COG0745	RESPONSE REGULATOR receiver
CXX37_RS08260	COG0531	amino acid
CXX37_RS08280	COG0033	Phosphoglucomutase
CXX37_RS08285	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CXX37_RS08290	COG0596	Alpha beta hydrolase
CXX37_RS08300	COG0716	FMN binding
CXX37_RS08310	COG0735	belongs to the Fur family
CXX37_RS08330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXX37_RS08330	COG1263	PTS System
CXX37_RS08330	COG2190	(PTS) system
CXX37_RS08340	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CXX37_RS08345	COG1846	Transcriptional regulator
CXX37_RS08345	COG1940	carbohydrate kinase activity
CXX37_RS08350	COG0647	UMP catabolic process
CXX37_RS08355	COG0367	asparagine synthase
CXX37_RS08395	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CXX37_RS08405	COG1702	phosphate starvation-inducible protein PhoH
CXX37_RS08415	COG4535	Mg2 and Co2 transporter CorC
CXX37_RS08420	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CXX37_RS08425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXX37_RS08430	COG0765	amino acid transport
CXX37_RS08435	COG0765	amino acid transport
CXX37_RS08440	COG1126	abc transporter atp-binding protein
CXX37_RS08450	COG0443	Heat shock 70 kDa protein
CXX37_RS08455	COG2214	Heat shock protein DnaJ domain protein
CXX37_RS08465	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CXX37_RS08470	COG2214	Heat shock protein DnaJ domain protein
CXX37_RS08480	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CXX37_RS08485	COG2888	peptidyl-tyrosine sulfation
CXX37_RS08500	COG1466	dna polymerase III delta subunit
CXX37_RS08510	COG0406	alpha-ribazole phosphatase activity
CXX37_RS08515	COG0799	negative regulation of ribosome biogenesis
CXX37_RS08525	COG0768	penicillin binding
CXX37_RS08530	COG0772	Belongs to the SEDS family
CXX37_RS08535	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CXX37_RS08540	COG1686	Belongs to the peptidase S11 family
CXX37_RS08555	COG0583	DNA-binding transcription factor activity
CXX37_RS08565	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CXX37_RS08570	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CXX37_RS08590	COG3069	C4-dicarboxylate transmembrane transporter activity
CXX37_RS08595	COG4565	transcriptional regulatory protein
CXX37_RS08600	COG3290	protein histidine kinase activity
CXX37_RS08605	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
CXX37_RS08615	COG2301	Belongs to the HpcH HpaI aldolase family
CXX37_RS08620	COG3051	citrate lyase alpha subunit
CXX37_RS08635	COG0471	metal ion transport
CXX37_RS08640	COG3719	Belongs to the RNase T2 family
CXX37_RS08645	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CXX37_RS08650	COG1063	alcohol dehydrogenase
CXX37_RS08670	COG3634	alkyl hydroperoxide reductase activity
CXX37_RS08675	COG0450	alkyl hydroperoxide reductase
CXX37_RS08680	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CXX37_RS08685	COG0583	DNA-binding transcription factor activity
CXX37_RS08690	COG3969	phosphoadenosine phosphosulfate
CXX37_RS08695	COG1475	DNA binding
CXX37_RS08700	COG0436	Aminotransferase
CXX37_RS08705	COG0371	Dehydrogenase
CXX37_RS08710	COG2879	small protein
CXX37_RS08715	COG1966	Carbon starvation protein
CXX37_RS08720	COG2050	protein possibly involved in aromatic compounds catabolism
CXX37_RS08725	COG1028	Short-chain dehydrogenase reductase Sdr
CXX37_RS08730	COG1535	isochorismatase
CXX37_RS08730	COG3433	isochorismatase activity
CXX37_RS08735	COG1021	2,3-dihydroxybenzoate-AMP ligase
CXX37_RS08740	COG1169	isochorismate synthase
CXX37_RS08745	COG4592	Periplasmic binding protein
CXX37_RS08755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CXX37_RS08760	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CXX37_RS08765	COG1120	ATPase activity
CXX37_RS08770	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CXX37_RS08775	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXX37_RS08775	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CXX37_RS08780	COG3251	PFAM MbtH domain protein
CXX37_RS08785	COG2382	esterase
CXX37_RS08790	COG4771	TonB-dependent receptor
CXX37_RS08795	COG2977	Belongs to the P-Pant transferase superfamily
CXX37_RS08800	COG3385	transposase activity
CXX37_RS08835	COG2315	Protein conserved in bacteria
CXX37_RS08840	COG0778	Nitroreductase
CXX37_RS08845	COG0668	transmembrane transport
CXX37_RS08850	COG1113	amino acid transport
CXX37_RS08855	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CXX37_RS08860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CXX37_RS08865	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CXX37_RS08890	COG5562	phage envelope protein
CXX37_RS08905	COG3772	lysozyme
CXX37_RS08925	COG3039	Transposase
CXX37_RS08935	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CXX37_RS09075	COG0582	viral genome integration into host DNA
CXX37_RS09085	COG2197	response regulator
CXX37_RS09090	COG3539	Fimbrial protein
CXX37_RS09095	COG3539	Fimbrial protein
CXX37_RS09100	COG3188	usher protein
CXX37_RS09105	COG3121	Chaperone
CXX37_RS09120	COG2501	S4 domain
CXX37_RS09125	COG1988	membrane-bound metal-dependent
CXX37_RS09135	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CXX37_RS09145	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CXX37_RS09150	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CXX37_RS09155	COG0549	Belongs to the carbamate kinase family
CXX37_RS09165	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CXX37_RS09170	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CXX37_RS09175	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CXX37_RS09180	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CXX37_RS09185	COG3257	ureidoglycine aminohydrolase activity
CXX37_RS09190	COG1929	Belongs to the glycerate kinase type-1 family
CXX37_RS09195	COG2233	PERMEase
CXX37_RS09205	COG1953	Uracil, thiamine, allantoin
CXX37_RS09210	COG2084	Dehydrogenase
CXX37_RS09215	COG3622	Belongs to the hyi family
CXX37_RS09220	COG3960	tartronate-semialdehyde synthase activity
CXX37_RS09225	COG1414	Transcriptional regulator
CXX37_RS09235	COG0583	DNA-binding transcription factor activity
CXX37_RS09265	COG3209	COG3209 Rhs family protein
CXX37_RS09270	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CXX37_RS09275	COG4181	ATPase activity
CXX37_RS09280	COG2755	lipolytic protein G-D-S-L family
CXX37_RS09285	COG0300	oxidoreductase activity
CXX37_RS09290	COG3118	belongs to the thioredoxin family
CXX37_RS09295	COG0390	transport system, permease component
CXX37_RS09300	COG4619	ABC transporter
CXX37_RS09305	COG0330	HflC and HflK could
CXX37_RS09310	COG1585	Membrane protein implicated in regulation of membrane protease activity
CXX37_RS09315	COG0789	Transcriptional regulator
CXX37_RS09320	COG0531	amino acid
CXX37_RS09325	COG2066	Belongs to the glutaminase family
CXX37_RS09330	COG2217	Heavy metal translocating P-type atpase
CXX37_RS09335	COG3093	addiction module antidote protein HigA
CXX37_RS09345	COG3735	TraB family
CXX37_RS09350	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CXX37_RS09355	COG0737	Belongs to the 5'-nucleotidase family
CXX37_RS09360	COG2223	nitrite transmembrane transporter activity
CXX37_RS09365	COG4651	solute:proton antiporter activity
CXX37_RS09365	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CXX37_RS09370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CXX37_RS09405	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CXX37_RS09415	COG2832	Protein of unknown function (DUF454)
CXX37_RS09420	COG3923	Primosomal replication protein n
CXX37_RS09430	COG1196	nuclear chromosome segregation
CXX37_RS09430	COG3264	Mechanosensitive ion channel
CXX37_RS09435	COG1309	transcriptional regulator
CXX37_RS09440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CXX37_RS09445	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CXX37_RS09460	COG0110	maltose O-acetyltransferase activity
CXX37_RS09470	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CXX37_RS09475	COG5507	3-demethylubiquinone-9 3-methyltransferase
CXX37_RS09485	COG3695	enzyme binding
CXX37_RS09490	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CXX37_RS09495	COG1946	Acyl-CoA thioesterase
CXX37_RS09500	COG0004	ammonium transporteR
CXX37_RS09505	COG0347	Belongs to the P(II) protein family
CXX37_RS09510	COG1132	(ABC) transporter
CXX37_RS09515	COG1132	(ABC) transporter
CXX37_RS09520	COG1522	sequence-specific DNA binding
CXX37_RS09530	COG4533	DNA binding
CXX37_RS09540	COG0824	Thioesterase
CXX37_RS09545	COG1555	photosystem II stabilization
CXX37_RS09550	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CXX37_RS09555	COG0776	regulation of translation
CXX37_RS09560	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CXX37_RS09580	COG0271	Belongs to the BolA IbaG family
CXX37_RS09585	COG3056	Lipoprotein
CXX37_RS09590	COG2223	nitrite transmembrane transporter activity
CXX37_RS09595	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CXX37_RS09600	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CXX37_RS09605	COG1845	cytochrome c oxidase, subunit III
CXX37_RS09610	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CXX37_RS09620	COG2814	Major facilitator Superfamily
CXX37_RS09630	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CXX37_RS09635	COG0693	protein deglycase activity
CXX37_RS09650	COG0142	geranyltranstransferase activity
CXX37_RS09660	COG0667	Aldo Keto reductase
CXX37_RS09665	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CXX37_RS09670	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CXX37_RS09685	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CXX37_RS09685	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CXX37_RS09695	COG4238	major outer membrane lipoprotein
CXX37_RS09700	COG3248	Nucleoside-binding outer membrane protein
CXX37_RS09705	COG1403	HNH endonuclease
CXX37_RS09710	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CXX37_RS09715	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CXX37_RS09720	COG1862	Preprotein translocase
CXX37_RS09740	COG0366	Alpha amylase catalytic
CXX37_RS09745	COG1113	amino acid transport
CXX37_RS09750	COG1114	Component of the transport system for branched-chain amino acids
CXX37_RS09755	COG5002	protein histidine kinase activity
CXX37_RS09760	COG0745	RESPONSE REGULATOR receiver
CXX37_RS09765	COG0420	3'-5' exonuclease activity
CXX37_RS09770	COG0419	ATPase involved in DNA repair
CXX37_RS09775	COG2814	Major facilitator Superfamily
CXX37_RS09780	COG1940	carbohydrate kinase activity
CXX37_RS09805	COG4126	flavin adenine dinucleotide binding
CXX37_RS09825	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CXX37_RS09830	COG3706	GGDEF domain
CXX37_RS09840	COG1785	Belongs to the alkaline phosphatase family
CXX37_RS09850	COG1181	Belongs to the D-alanine--D-alanine ligase family
CXX37_RS09870	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CXX37_RS09875	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CXX37_RS09880	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CXX37_RS09890	COG4372	Transposase
CXX37_RS09895	COG3436	PFAM IS66 Orf2 family protein
CXX37_RS09915	COG0113	porphobilinogen synthase activity
CXX37_RS09920	COG2175	clavaminate synthase activity
CXX37_RS09925	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CXX37_RS09930	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CXX37_RS09935	COG4521	taurine ABC transporter
CXX37_RS09940	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CXX37_RS09945	COG1215	transferase activity, transferring glycosyl groups
CXX37_RS09975	COG3122	Protein conserved in bacteria
CXX37_RS09980	COG2814	Major facilitator Superfamily
CXX37_RS09995	COG3971	2-oxopent-4-enoate hydratase activity
CXX37_RS10015	COG1414	Transcriptional regulator
CXX37_RS10020	COG1609	Transcriptional regulator
CXX37_RS10025	COG3250	beta-galactosidase activity
CXX37_RS10030	COG2223	nitrite transmembrane transporter activity
CXX37_RS10035	COG0110	maltose O-acetyltransferase activity
CXX37_RS10040	COG2807	transmembrane transport
CXX37_RS10050	COG0288	reversible hydration of carbon dioxide
CXX37_RS10055	COG0583	DNA-binding transcription factor activity
CXX37_RS10060	COG0402	S-adenosylhomocysteine deaminase activity
CXX37_RS10065	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CXX37_RS10070	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CXX37_RS10075	COG2079	MmgE PrpD family protein
CXX37_RS10080	COG0372	Belongs to the citrate synthase family
CXX37_RS10085	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CXX37_RS10090	COG3829	transcription factor binding
CXX37_RS10100	COG1280	lysine exporter protein (LysE YggA)
CXX37_RS10125	COG0402	S-adenosylhomocysteine deaminase activity
CXX37_RS10130	COG0549	Belongs to the carbamate kinase family
CXX37_RS10140	COG1304	FMN binding
CXX37_RS10165	COG0666	response to abiotic stimulus
CXX37_RS10175	COG0583	DNA-binding transcription factor activity
CXX37_RS10180	COG2200	EAL domain
CXX37_RS10180	COG2771	luxR family
CXX37_RS10190	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CXX37_RS10215	COG1556	Lactate utilization protein
CXX37_RS10220	COG1139	Iron-sulfur cluster binding protein
CXX37_RS10225	COG0247	lactate metabolic process
CXX37_RS10230	COG2207	Transcriptional regulator
CXX37_RS10235	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CXX37_RS10265	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CXX37_RS10285	COG2195	Cleaves the N-terminal amino acid of tripeptides
CXX37_RS10290	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CXX37_RS10295	COG1690	Belongs to the RtcB family
CXX37_RS10300	COG0454	-acetyltransferase
CXX37_RS10310	COG2161	toxin-antitoxin pair type II binding
CXX37_RS10325	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CXX37_RS10330	COG1191	sigma factor activity
CXX37_RS10355	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CXX37_RS10365	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CXX37_RS10385	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CXX37_RS10410	COG4786	Flagellar basal body rod
CXX37_RS10415	COG4787	bacterial-type flagellum-dependent cell motility
CXX37_RS10420	COG1749	Flagellar hook protein flgE
CXX37_RS10430	COG1558	bacterial-type flagellum-dependent cell motility
CXX37_RS10435	COG1815	bacterial-type flagellum-dependent cell motility
CXX37_RS10465	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CXX37_RS10485	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CXX37_RS10495	COG1677	Flagellar hook-basal body complex protein FliE
CXX37_RS10520	COG1987	bacterial-type flagellum assembly
CXX37_RS10540	COG1943	Transposase
CXX37_RS10545	COG0791	NLP P60 protein
CXX37_RS10550	COG3077	Addiction module antitoxin, RelB DinJ family
CXX37_RS10555	COG3041	Addiction module toxin RelE StbE family
CXX37_RS10560	COG3034	peptidoglycan biosynthetic process
CXX37_RS10565	COG0121	glutamine amidotransferase
CXX37_RS10575	COG1960	acyl-CoA dehydrogenase activity
CXX37_RS10585	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CXX37_RS10590	COG5433	transposase activity
CXX37_RS10600	COG3209	COG3209 Rhs family protein
CXX37_RS10690	COG3157	Type VI secretion system effector, Hcp
CXX37_RS10695	COG4104	PAAR repeat-containing protein
CXX37_RS10710	COG0582	viral genome integration into host DNA
CXX37_RS10725	COG4983	Phage plasmid primase, P4 family domain protein
CXX37_RS10760	COG3436	PFAM IS66 Orf2 family protein
CXX37_RS10765	COG4372	Transposase
CXX37_RS10805	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CXX37_RS10825	COG3596	GTP binding
CXX37_RS10835	COG2378	regulation of single-species biofilm formation
CXX37_RS10845	COG2378	regulation of single-species biofilm formation
CXX37_RS10875	COG2003	Belongs to the UPF0758 family
CXX37_RS10915	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CXX37_RS10925	COG2226	methyltransferase
CXX37_RS10935	COG0741	lytic transglycosylase activity
CXX37_RS10935	COG1388	LysM domain
CXX37_RS10940	COG2226	methyltransferase
CXX37_RS10950	COG0583	DNA-binding transcription factor activity
CXX37_RS10955	COG0656	L-ascorbic acid biosynthetic process
CXX37_RS10990	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CXX37_RS10995	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CXX37_RS11000	COG2011	ABC-type metal ion transport system permease component
CXX37_RS11005	COG1464	Belongs to the NlpA lipoprotein family
CXX37_RS11015	COG1720	tRNA m6t6A37 methyltransferase activity
CXX37_RS11025	COG0791	NLP P60 protein
CXX37_RS11030	COG3015	lipoprotein NlpE involved in copper resistance
CXX37_RS11035	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CXX37_RS11040	COG4681	YaeQ
CXX37_RS11050	COG4568	rho-dependent transcription termination
CXX37_RS11055	COG0037	tRNA processing
CXX37_RS11060	COG0346	lactoylglutathione lyase activity
CXX37_RS11065	COG1982	Orn Lys Arg decarboxylase major
CXX37_RS11075	COG0587	DNA-directed DNA polymerase activity
CXX37_RS11100	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CXX37_RS11105	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CXX37_RS11115	COG0750	zinc metalloprotease
CXX37_RS11120	COG0575	Belongs to the CDS family
CXX37_RS11125	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CXX37_RS11130	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CXX37_RS11155	COG0024	Methionine aminopeptidase
CXX37_RS11170	COG1408	metallophosphoesterase
CXX37_RS11185	COG3835	regulator
CXX37_RS11190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CXX37_RS11205	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CXX37_RS11210	COG2860	membrane
CXX37_RS11235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CXX37_RS11240	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CXX37_RS11245	COG1120	ATPase activity
CXX37_RS11250	COG4774	siderophore transport
CXX37_RS11255	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CXX37_RS11260	COG1643	Atp-dependent helicase
CXX37_RS11265	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CXX37_RS11275	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CXX37_RS11285	COG0617	tRNA 3'-terminal CCA addition
CXX37_RS11290	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CXX37_RS11295	COG3539	Fimbrial protein
CXX37_RS11300	COG3121	Chaperone
CXX37_RS11305	COG3188	usher protein
CXX37_RS11310	COG3539	Fimbrial protein
CXX37_RS11315	COG3539	Fimbrial protein
CXX37_RS11320	COG3539	Fimbrial protein
CXX37_RS11325	COG3539	Fimbrial protein
CXX37_RS11340	COG5464	transposase or invertase
CXX37_RS11350	COG0726	polysaccharide deacetylase
CXX37_RS11355	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX37_RS11360	COG0842	Transport permease protein
CXX37_RS11365	COG1131	(ABC) transporter
CXX37_RS11370	COG0288	reversible hydration of carbon dioxide
CXX37_RS11375	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CXX37_RS11385	COG2132	Multicopper oxidase
CXX37_RS11410	COG1049	propionate catabolic process, 2-methylcitrate cycle
CXX37_RS11415	COG3064	Membrane
CXX37_RS11420	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CXX37_RS11425	COG0508	dehydrogenase complex catalyzes the overall conversion of
CXX37_RS11430	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CXX37_RS11435	COG2186	Transcriptional regulator
CXX37_RS11445	COG3725	Membrane protein required for beta-lactamase induction
CXX37_RS11450	COG3023	N-Acetylmuramoyl-L-alanine amidase
CXX37_RS11455	COG0157	Belongs to the NadC ModD family
CXX37_RS11460	COG4969	Belongs to the N-Me-Phe pilin family
CXX37_RS11465	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CXX37_RS11470	COG1459	type II secretion system
CXX37_RS11480	COG0237	dephospho-CoA kinase activity
CXX37_RS11495	COG0494	nUDIX hydrolase
CXX37_RS11515	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CXX37_RS11520	COG0849	cell division
CXX37_RS11525	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CXX37_RS11530	COG1181	Belongs to the D-alanine--D-alanine ligase family
CXX37_RS11545	COG0772	Belongs to the SEDS family
CXX37_RS11550	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CXX37_RS11560	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CXX37_RS11565	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CXX37_RS11570	COG0768	penicillin binding
CXX37_RS11575	COG3116	cell division
CXX37_RS11590	COG1609	Transcriptional regulator
CXX37_RS11600	COG0440	acetolactate synthase activity
CXX37_RS11605	COG0028	Belongs to the TPP enzyme family
CXX37_RS11615	COG0583	DNA-binding transcription factor activity
CXX37_RS11630	COG0473	3-isopropylmalate dehydrogenase activity
CXX37_RS11645	COG2814	Major facilitator Superfamily
CXX37_RS11660	COG4143	(ABC) transporter
CXX37_RS11665	COG1178	ABC-type Fe3 transport system permease component
CXX37_RS11675	COG0586	Pfam SNARE associated Golgi protein
CXX37_RS11680	COG4977	sequence-specific DNA binding
CXX37_RS11695	COG0235	Class ii aldolase
CXX37_RS11700	COG0417	DNA replication proofreading
CXX37_RS11710	COG0564	pseudouridine synthase activity
CXX37_RS11715	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CXX37_RS11720	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CXX37_RS11725	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CXX37_RS11750	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CXX37_RS11765	COG2271	Major facilitator Superfamily
CXX37_RS11770	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CXX37_RS11825	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CXX37_RS11830	COG0505	Belongs to the CarA family
CXX37_RS11850	COG1047	Peptidyl-prolyl cis-trans
CXX37_RS11865	COG0196	riboflavin kinase activity
CXX37_RS11885	COG0583	DNA-binding transcription factor activity
CXX37_RS11890	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CXX37_RS11900	COG3385	transposase activity
CXX37_RS11920	COG4735	regulation of single-species biofilm formation
CXX37_RS11925	COG1584	GPR1 FUN34 yaaH family protein
CXX37_RS11930	COG0521	Mo-molybdopterin cofactor biosynthetic process
CXX37_RS11935	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CXX37_RS11940	COG1115	amino acid carrier protein
CXX37_RS11955	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CXX37_RS11965	COG0460	homoserine dehydrogenase
CXX37_RS11965	COG0527	aspartate kinase activity
CXX37_RS11975	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CXX37_RS11985	COG0745	RESPONSE REGULATOR receiver
CXX37_RS11990	COG4452	Inner membrane protein CreD
CXX37_RS11995	COG2205	protein histidine kinase activity
CXX37_RS12000	COG0745	RESPONSE REGULATOR receiver
CXX37_RS12005	COG3045	CreA protein
CXX37_RS12010	COG2207	Transcriptional regulator
CXX37_RS12010	COG3708	Transcriptional regulator
CXX37_RS12030	COG0741	lytic transglycosylase activity
CXX37_RS12035	COG0488	(ABC) transporter
CXX37_RS12040	COG3172	ATPase kinase involved in NAD metabolism
CXX37_RS12040	COG1056	cytidyltransferase-related domain
CXX37_RS12045	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CXX37_RS12050	COG0560	Phosphoserine phosphatase
CXX37_RS12055	COG3726	membrane protein affecting hemolysin expression
CXX37_RS12065	COG3550	peptidyl-serine autophosphorylation
CXX37_RS12090	COG1328	CTP reductase activity
CXX37_RS12095	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CXX37_RS12100	COG0084	hydrolase, TatD family'
CXX37_RS12105	COG4667	esterase of the alpha-beta hydrolase superfamily
CXX37_RS12115	COG2823	Periplasmic or secreted lipoprotein
CXX37_RS12125	COG1011	Hydrolase
CXX37_RS12130	COG0456	acetyltransferase
CXX37_RS12135	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CXX37_RS12165	COG4114	ferric iron reductase
CXX37_RS12170	COG2197	response regulator
CXX37_RS12175	COG2197	response regulator
CXX37_RS12180	COG2966	Psort location CytoplasmicMembrane, score
CXX37_RS12195	COG1484	DNA-dependent DNA replication
CXX37_RS12210	COG1063	alcohol dehydrogenase
CXX37_RS12215	COG1802	Transcriptional regulator
CXX37_RS12220	COG2271	Major facilitator Superfamily
CXX37_RS12225	COG0840	transmembrane signaling receptor activity
CXX37_RS12230	COG1966	Carbon starvation protein
CXX37_RS12235	COG2879	small protein
CXX37_RS12240	COG0523	cobalamin synthesis protein
CXX37_RS12275	COG1924	4 iron, 4 sulfur cluster binding
CXX37_RS12280	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
CXX37_RS12285	COG2733	membrane
CXX37_RS12290	COG2814	Major facilitator Superfamily
CXX37_RS12300	COG0477	Major facilitator Superfamily
CXX37_RS12310	COG3366	ferrous iron transmembrane transporter activity
CXX37_RS12315	COG0700	Nucleoside recognition
CXX37_RS12320	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CXX37_RS12325	COG0583	DNA-binding transcription factor activity
CXX37_RS12345	COG2186	Transcriptional regulator
CXX37_RS12350	COG0246	Mannitol dehydrogenase
CXX37_RS12360	COG2610	gluconate transmembrane transporter activity
CXX37_RS12375	COG1595	DNA-templated transcription, initiation
CXX37_RS12380	COG3712	iron ion homeostasis
CXX37_RS12385	COG4772	TonB-dependent receptor
CXX37_RS12390	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CXX37_RS12395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CXX37_RS12400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CXX37_RS12405	COG1120	ATPase activity
CXX37_RS12475	COG2194	sulfuric ester hydrolase activity
CXX37_RS12480	COG0582	viral genome integration into host DNA
CXX37_RS12495	COG1064	alcohol dehydrogenase
CXX37_RS12505	COG0795	lipopolysaccharide-transporting ATPase activity
CXX37_RS12510	COG0795	lipopolysaccharide-transporting ATPase activity
CXX37_RS12520	COG2927	DNA polymerase III (CHI subunit)
CXX37_RS12525	COG0525	valine-tRNA ligase activity
CXX37_RS12530	COG4269	membrane
CXX37_RS12535	COG0456	acetyltransferase
CXX37_RS12540	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
CXX37_RS12565	COG1309	transcriptional regulator
CXX37_RS12570	COG1028	Short-chain dehydrogenase reductase Sdr
CXX37_RS12575	COG0251	oxidation-reduction process
CXX37_RS12595	COG0251	oxidation-reduction process
CXX37_RS12600	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CXX37_RS12610	COG1609	Transcriptional regulator
CXX37_RS12615	COG1263	PTS System
CXX37_RS12615	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXX37_RS12620	COG0366	Alpha amylase catalytic
CXX37_RS12625	COG1328	CTP reductase activity
CXX37_RS12630	COG0602	queuosine metabolic process
CXX37_RS12635	COG3783	Cytochrome b(562)
CXX37_RS12640	COG0312	modulator of DNA gyrase
CXX37_RS12650	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CXX37_RS12660	COG1172	Belongs to the binding-protein-dependent transport system permease family
CXX37_RS12665	COG1172	Belongs to the binding-protein-dependent transport system permease family
CXX37_RS12670	COG1129	ABC transporter
CXX37_RS12675	COG1879	ABC-type sugar transport system periplasmic component
CXX37_RS12680	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CXX37_RS12685	COG2105	PFAM AIG2 family protein
CXX37_RS12690	COG2911	Protein conserved in bacteria
CXX37_RS12695	COG0729	surface antigen
CXX37_RS12705	COG1253	flavin adenine dinucleotide binding
CXX37_RS12715	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CXX37_RS12720	COG1218	3'(2'),5'-bisphosphate nucleotidase
CXX37_RS12725	COG0737	Belongs to the 5'-nucleotidase family
CXX37_RS12730	COG1733	regulation of RNA biosynthetic process
CXX37_RS12735	COG0702	epimerase
CXX37_RS12740	COG0697	spore germination
CXX37_RS12750	COG1113	amino acid transport
CXX37_RS12755	COG0545	Peptidyl-prolyl cis-trans isomerase
CXX37_RS12765	COG3061	Opacity-associated protein A
CXX37_RS12770	COG1309	transcriptional regulator
CXX37_RS12785	COG1024	Enoyl-CoA hydratase
CXX37_RS12790	COG4670	ketone body catabolic process
CXX37_RS12795	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CXX37_RS12800	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CXX37_RS12810	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CXX37_RS12820	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CXX37_RS12860	COG3414	Phosphotransferase system galactitol-specific IIB component
CXX37_RS12865	COG3037	sugar-specific permease SgaT UlaA
CXX37_RS12880	COG1073	alpha beta
CXX37_RS12885	COG3650	response to hydrogen peroxide
CXX37_RS12895	COG1960	acyl-CoA dehydrogenase activity
CXX37_RS12900	COG0754	glutathionylspermidine amidase activity
CXX37_RS12905	COG5463	Belongs to the UPF0441 family
CXX37_RS12910	COG3766	membrane
CXX37_RS12920	COG1842	Phage shock protein A
CXX37_RS12925	COG3789	protein conserved in bacteria
CXX37_RS12930	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CXX37_RS12935	COG0557	exoribonuclease II activity
CXX37_RS12950	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CXX37_RS12955	COG0330	HflC and HflK could
CXX37_RS12960	COG0330	HflC and HflK could
CXX37_RS12965	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CXX37_RS12985	COG0860	N-Acetylmuramoyl-L-alanine amidase
CXX37_RS12990	COG0802	atpase or kinase
CXX37_RS12995	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CXX37_RS12995	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CXX37_RS13000	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CXX37_RS13040	COG1511	domain protein
CXX37_RS13040	COG3264	Mechanosensitive ion channel
CXX37_RS13055	COG0531	amino acid
CXX37_RS13065	COG1053	succinate dehydrogenase
CXX37_RS13070	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CXX37_RS13085	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CXX37_RS13090	COG3040	lipid binding
CXX37_RS13095	COG2076	Multidrug Resistance protein
CXX37_RS13100	COG5510	response to toxic substance
CXX37_RS13105	COG5510	response to toxic substance
CXX37_RS13115	COG1509	lysine 2,3-aminomutase activity
CXX37_RS13140	COG0531	amino acid
CXX37_RS13145	COG3030	protein affecting phage T7 exclusion by the F plasmid
CXX37_RS13150	COG1027	Aspartate ammonia-lyase
CXX37_RS13155	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CXX37_RS13165	COG4232	protein-disulfide reductase activity
CXX37_RS13170	COG1309	transcriptional regulator
CXX37_RS13180	COG3710	Transcriptional regulator
CXX37_RS13185	COG0531	amino acid
CXX37_RS13190	COG1982	Orn Lys Arg decarboxylase major
CXX37_RS13195	COG3104	oligopeptide transport
CXX37_RS13220	COG2388	GCN5-related N-acetyl-transferase
CXX37_RS13225	COG3592	Divergent 4Fe-4S mono-cluster
CXX37_RS13230	COG3290	protein histidine kinase activity
CXX37_RS13235	COG4565	transcriptional regulatory protein
CXX37_RS13240	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CXX37_RS13245	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CXX37_RS13245	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CXX37_RS13250	COG3647	Membrane
CXX37_RS13255	COG2211	Major facilitator Superfamily
CXX37_RS13260	COG1486	melibiose metabolic process
CXX37_RS13265	COG2169	Transcriptional regulator
CXX37_RS13270	COG1982	Orn Lys Arg decarboxylase major
CXX37_RS13275	COG2207	Transcriptional regulator
CXX37_RS13280	COG0531	amino acid
CXX37_RS13285	COG2194	sulfuric ester hydrolase activity
CXX37_RS13290	COG0745	RESPONSE REGULATOR receiver
CXX37_RS13295	COG0642	Histidine kinase
CXX37_RS13305	COG0477	Major facilitator Superfamily
CXX37_RS13315	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CXX37_RS13320	COG2824	Alkylphosphonate utilization operon protein PhnA
CXX37_RS13325	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CXX37_RS13335	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CXX37_RS13340	COG3639	organic phosphonate transmembrane transporter activity
CXX37_RS13345	COG2188	Transcriptional regulator
CXX37_RS13350	COG3624	Phosphonate C-P lyase system protein PhnG
CXX37_RS13355	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CXX37_RS13360	COG3626	phosphonate metabolism
CXX37_RS13365	COG3627	carbon phosphorus lyase activity
CXX37_RS13370	COG4107	phosphonate C-P lyase system protein PhnK
CXX37_RS13375	COG4778	phosphonate C-P lyase system protein PhnL
CXX37_RS13380	COG3454	Phosphonate metabolism
CXX37_RS13385	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CXX37_RS13390	COG0456	acetyltransferase
CXX37_RS13395	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CXX37_RS13405	COG0698	ribose 5-phosphate isomerase
CXX37_RS13410	COG1737	Transcriptional regulator
CXX37_RS13415	COG1879	ABC-type sugar transport system periplasmic component
CXX37_RS13420	COG1129	ABC transporter
CXX37_RS13425	COG1172	Belongs to the binding-protein-dependent transport system permease family
CXX37_RS13430	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CXX37_RS13435	COG1940	carbohydrate kinase activity
CXX37_RS13440	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CXX37_RS13450	COG1566	PFAM secretion protein HlyD family protein
CXX37_RS13455	COG1289	transmembrane transporter activity
CXX37_RS13470	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CXX37_RS13475	COG1301	dicarboxylic acid transport
CXX37_RS13480	COG4235	cytochrome complex assembly
CXX37_RS13485	COG3088	subunit of a heme lyase
CXX37_RS13490	COG1138	Cytochrome C-type biogenesis protein
CXX37_RS13495	COG3301	Polysulphide reductase, NrfD
CXX37_RS13500	COG0437	4 iron, 4 sulfur cluster binding
CXX37_RS13505	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CXX37_RS13515	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CXX37_RS13520	COG3162	membrane
CXX37_RS13535	COG0025	NhaP-type Na H and K H
CXX37_RS13540	COG2252	PERMEase
CXX37_RS13545	COG0789	Transcriptional regulator
CXX37_RS13550	COG2207	Transcriptional regulator
CXX37_RS13555	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CXX37_RS13565	COG0629	single-stranded DNA binding
CXX37_RS13570	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CXX37_RS13575	COG2315	Protein conserved in bacteria
CXX37_RS13580	COG0432	Pfam Uncharacterised protein family UPF0047
CXX37_RS13585	COG3700	Belongs to the class B bacterial acid phosphatase family
CXX37_RS13595	COG1448	Aminotransferase
CXX37_RS13600	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CXX37_RS13605	COG0305	Participates in initiation and elongation during chromosome replication
CXX37_RS13610	COG0604	alcohol dehydrogenase
CXX37_RS13620	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CXX37_RS13655	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CXX37_RS13665	COG3778	Protein conserved in bacteria
CXX37_RS13670	COG3299	homolog of phage Mu protein gp47
CXX37_RS13690	COG4228	DNA circulation
CXX37_RS13715	COG4386	tail sheath protein
CXX37_RS13760	COG4626	Terminase
CXX37_RS13760	COG1802	Transcriptional regulator
CXX37_RS13815	COG1403	HNH endonuclease
CXX37_RS13835	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CXX37_RS13845	COG4725	Belongs to the MT-A70-like family
CXX37_RS13855	COG1846	Transcriptional regulator
CXX37_RS13875	COG4197	protein conserved in bacteria, prophage-related
CXX37_RS13880	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CXX37_RS13900	COG5532	Uncharacterized conserved protein (DUF2303)
CXX37_RS13905	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CXX37_RS13940	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CXX37_RS13955	COG0735	belongs to the Fur family
CXX37_RS13960	COG3237	CsbD-like
CXX37_RS13965	COG0534	Mate efflux family protein
CXX37_RS13975	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CXX37_RS14010	COG3842	ATPase activity
CXX37_RS14015	COG2182	Extracellular solute-binding protein
CXX37_RS14020	COG1175	transmembrane transport
CXX37_RS14025	COG3833	ABC-type maltose transport systems, permease component
CXX37_RS14030	COG2814	Major facilitator Superfamily
CXX37_RS14030	COG0477	Major facilitator Superfamily
CXX37_RS14045	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CXX37_RS14075	COG0527	aspartate kinase activity
CXX37_RS14085	COG1187	pseudouridine synthase activity
CXX37_RS14095	COG1283	sodium-dependent phosphate transmembrane transporter activity
CXX37_RS14100	COG1410	methionine synthase
CXX37_RS14100	COG0646	methionine synthase
CXX37_RS14105	COG1414	Transcriptional regulator
CXX37_RS14125	COG2224	Isocitrate lyase
CXX37_RS14130	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CXX37_RS14140	COG0456	acetyltransferase
CXX37_RS14170	COG0151	Belongs to the GarS family
CXX37_RS14175	COG2204	response regulator
CXX37_RS14180	COG4191	Histidine kinase
CXX37_RS14185	COG3678	ATP-independent chaperone mediated protein folding
CXX37_RS14200	COG3068	Protein conserved in bacteria
CXX37_RS14235	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CXX37_RS14240	COG2104	thiamine diphosphate biosynthetic process
CXX37_RS14250	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CXX37_RS14285	COG0250	Participates in transcription elongation, termination and antitermination
CXX37_RS14290	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CXX37_RS14325	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CXX37_RS14325	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CXX37_RS14360	COG4206	TonB-dependent receptor
CXX37_RS14375	COG1309	transcriptional regulator
CXX37_RS14385	COG0583	DNA-binding transcription factor activity
CXX37_RS14400	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CXX37_RS14415	COG2194	sulfuric ester hydrolase activity
CXX37_RS14420	COG2207	Transcriptional regulator
CXX37_RS14425	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CXX37_RS14430	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CXX37_RS14435	COG1882	Formate acetyltransferase
CXX37_RS14440	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CXX37_RS14445	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CXX37_RS14450	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX37_RS14450	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX37_RS14450	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CXX37_RS14455	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CXX37_RS14460	COG0371	Dehydrogenase
CXX37_RS14465	COG3738	Protein conserved in bacteria
CXX37_RS14470	COG0697	spore germination
CXX37_RS14480	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CXX37_RS14485	COG0527	aspartate kinase activity
CXX37_RS14485	COG0460	homoserine dehydrogenase
CXX37_RS14490	COG0626	cystathionine gamma-synthase activity
CXX37_RS14500	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
CXX37_RS14535	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CXX37_RS14540	COG1609	Transcriptional regulator
CXX37_RS14545	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CXX37_RS14560	COG1575	Belongs to the MenA family. Type 1 subfamily
CXX37_RS14575	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CXX37_RS14585	COG1494	fructose-1,6-bisphosphatase
CXX37_RS14595	COG0589	response to stress
CXX37_RS14600	COG3691	Protein conserved in bacteria
CXX37_RS14605	COG3152	Membrane
CXX37_RS14625	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CXX37_RS14640	COG3678	ATP-independent chaperone mediated protein folding
CXX37_RS14645	COG0745	RESPONSE REGULATOR receiver
CXX37_RS14650	COG2205	protein histidine kinase activity
CXX37_RS14655	COG2258	MOSC domain
CXX37_RS14665	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CXX37_RS14705	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX37_RS14715	COG1363	Peptidase, m42
CXX37_RS14720	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX37_RS14720	COG3711	transcriptional antiterminator
CXX37_RS14735	COG0243	molybdopterin cofactor binding
CXX37_RS14735	COG3383	formate dehydrogenase (NAD+) activity
CXX37_RS14740	COG0243	molybdopterin cofactor binding
CXX37_RS14740	COG3383	formate dehydrogenase (NAD+) activity
CXX37_RS14745	COG0437	4 iron, 4 sulfur cluster binding
CXX37_RS14750	COG2864	formate dehydrogenase
CXX37_RS14760	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CXX37_RS14765	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CXX37_RS14770	COG0456	acetyltransferase
CXX37_RS14785	COG1011	Hydrolase
CXX37_RS14790	COG1349	DNA-binding transcription factor activity
CXX37_RS14800	COG2084	Dehydrogenase
CXX37_RS14805	COG3684	Belongs to the aldolase LacD family
CXX37_RS14810	COG2942	2-epimerase
CXX37_RS14815	COG2017	converts alpha-aldose to the beta-anomer
CXX37_RS14820	COG1501	Belongs to the glycosyl hydrolase 31 family
CXX37_RS14825	COG2211	Major facilitator Superfamily
CXX37_RS14830	COG2211	Major facilitator Superfamily
CXX37_RS14835	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CXX37_RS14840	COG2271	Major facilitator Superfamily
CXX37_RS14845	COG1082	Xylose isomerase domain protein TIM barrel
CXX37_RS14850	COG2188	Transcriptional regulator
CXX37_RS14855	COG1217	gtp-binding protein TYPA
CXX37_RS14860	COG0174	glutamine synthetase
CXX37_RS14865	COG3852	Histidine kinase
CXX37_RS14870	COG2204	response regulator
CXX37_RS14880	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CXX37_RS14895	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CXX37_RS14895	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CXX37_RS14905	COG0204	Acyl-transferase
CXX37_RS14910	COG5339	Protein conserved in bacteria
CXX37_RS14915	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CXX37_RS14920	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CXX37_RS14925	COG3084	Protein conserved in bacteria
CXX37_RS14930	COG0746	molybdenum cofactor guanylyltransferase activity
CXX37_RS14935	COG1763	Mo-molybdopterin cofactor biosynthetic process
CXX37_RS14965	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CXX37_RS14970	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CXX37_RS14975	COG1739	Uncharacterized protein family UPF0029
CXX37_RS14990	COG0183	Belongs to the thiolase family
CXX37_RS14995	COG0543	2 iron, 2 sulfur cluster binding
CXX37_RS15000	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CXX37_RS15005	COG0250	Participates in transcription elongation, termination and antitermination
CXX37_RS15010	COG0084	hydrolase, TatD family'
CXX37_RS15015	COG0805	protein transport
CXX37_RS15020	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CXX37_RS15025	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CXX37_RS15035	COG3165	ubiquinone biosynthetic process from chorismate
CXX37_RS15045	COG1322	Protein conserved in bacteria
CXX37_RS15050	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CXX37_RS15055	COG0412	Dienelactone hydrolase
CXX37_RS15065	COG0583	DNA-binding transcription factor activity
CXX37_RS15070	COG0697	spore germination
CXX37_RS15075	COG0561	phosphatase activity
CXX37_RS15080	COG2267	carboxylic ester hydrolase activity
CXX37_RS15085	COG1280	lysine exporter protein (LysE YggA)
CXX37_RS15090	COG1280	lysine exporter protein (LysE YggA)
CXX37_RS15095	COG0514	ATP-dependent DNA helicase (RecQ)
CXX37_RS15100	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
CXX37_RS15105	COG2050	protein possibly involved in aromatic compounds catabolism
CXX37_RS15110	COG2962	Rard protein
CXX37_RS15125	COG0598	Magnesium transport protein CorA
CXX37_RS15130	COG3698	Phosphodiester glycosidase
CXX37_RS15135	COG0210	DNA helicase
CXX37_RS15140	COG1011	Hydrolase
CXX37_RS15150	COG3159	Protein conserved in bacteria
CXX37_RS15160	COG5567	small periplasmic lipoprotein
CXX37_RS15175	COG3072	Adenylate cyclase
CXX37_RS15185	COG1587	Uroporphyrinogen-III synthase
CXX37_RS15190	COG2959	enzyme of heme biosynthesis
CXX37_RS15195	COG3071	HemY protein
CXX37_RS15200	COG0641	radical SAM
CXX37_RS15225	COG1113	amino acid transport
CXX37_RS15245	COG2244	polysaccharide biosynthetic process
CXX37_RS15250	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CXX37_RS15255	COG0456	acetyltransferase
CXX37_RS15260	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CXX37_RS15265	COG1088	dTDP-glucose 4,6-dehydratase activity
CXX37_RS15270	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CXX37_RS15275	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CXX37_RS15280	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CXX37_RS15285	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CXX37_RS15290	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CXX37_RS15300	COG3118	belongs to the thioredoxin family
CXX37_RS15315	COG0210	DNA helicase
CXX37_RS15325	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CXX37_RS15335	COG0583	DNA-binding transcription factor activity
CXX37_RS15340	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CXX37_RS15350	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CXX37_RS15355	COG3978	acetolactate synthase activity
CXX37_RS15375	COG0606	chelatase, subunit chli
CXX37_RS15380	COG3085	chromosome segregation
CXX37_RS15420	COG2186	Transcriptional regulator
CXX37_RS15425	COG0477	Major facilitator Superfamily
CXX37_RS15430	COG1609	Transcriptional regulator
CXX37_RS15435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CXX37_RS15440	COG1879	ABC-type sugar transport system periplasmic component
CXX37_RS15445	COG1172	Belongs to the binding-protein-dependent transport system permease family
CXX37_RS15450	COG1129	ABC transporter
CXX37_RS15465	COG3385	transposase activity
CXX37_RS15485	COG1522	sequence-specific DNA binding
CXX37_RS15490	COG0716	FMN binding
CXX37_RS15505	COG3312	ion transport
CXX37_RS15565	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CXX37_RS15570	COG0573	inorganic phosphate transmembrane transporter activity
CXX37_RS15575	COG0581	inorganic phosphate transmembrane transporter activity
CXX37_RS15580	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CXX37_RS15585	COG0704	Plays a role in the regulation of phosphate uptake
CXX37_RS15590	COG3711	transcriptional antiterminator
CXX37_RS15595	COG1263	PTS System
CXX37_RS15595	COG2190	(PTS) system
CXX37_RS15595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXX37_RS15600	COG2723	6-phospho-beta-galactosidase activity
CXX37_RS15610	COG2382	esterase
CXX37_RS15615	COG0363	glucosamine-6-phosphate deaminase activity
CXX37_RS15625	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CXX37_RS15630	COG2252	PERMEase
CXX37_RS15635	COG0431	NADPH-dependent FMN reductase
CXX37_RS15640	COG2091	lysine biosynthetic process via aminoadipic acid
CXX37_RS15655	COG0814	amino acid
CXX37_RS15705	COG0592	DNA-directed DNA polymerase activity
CXX37_RS15715	COG0187	DNA topoisomerase II activity
CXX37_RS15720	COG3753	Protein conserved in bacteria
CXX37_RS15725	COG0561	phosphatase activity
CXX37_RS15735	COG2186	Transcriptional regulator
CXX37_RS15740	COG3734	2-keto-3-deoxy-galactonokinase
CXX37_RS15745	COG0800	Aldolase
CXX37_RS15755	COG2271	Major facilitator Superfamily
CXX37_RS15760	COG0644	oxidoreductase
CXX37_RS15765	COG0823	Involved in the tonB-independent uptake of proteins
CXX37_RS15770	COG5645	(Lipo)protein
CXX37_RS15805	COG2207	Transcriptional regulator
CXX37_RS15810	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CXX37_RS15815	COG3119	arylsulfatase activity
CXX37_RS15825	COG2149	membrane
CXX37_RS15835	COG0641	radical SAM
CXX37_RS15840	COG2814	Major facilitator Superfamily
CXX37_RS15855	COG0028	Belongs to the TPP enzyme family
CXX37_RS15860	COG0440	acetolactate synthase activity
CXX37_RS15865	COG2197	response regulator
CXX37_RS15870	COG3851	Histidine kinase
CXX37_RS15875	COG2271	Major facilitator Superfamily
CXX37_RS15880	COG2271	Major facilitator Superfamily
CXX37_RS15890	COG2252	PERMEase
CXX37_RS15910	COG1464	Belongs to the NlpA lipoprotein family
CXX37_RS15915	COG0697	spore germination
CXX37_RS15920	COG2814	Major facilitator Superfamily
CXX37_RS15935	COG2211	Major facilitator Superfamily
CXX37_RS15940	COG1501	Belongs to the glycosyl hydrolase 31 family
CXX37_RS15945	COG2982	Protein involved in outer membrane biogenesis
CXX37_RS15950	COG2233	PERMEase
CXX37_RS15955	COG0786	glutamate:sodium symporter activity
CXX37_RS15960	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CXX37_RS15965	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CXX37_RS15970	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CXX37_RS15980	COG0194	GDP metabolic process
CXX37_RS15990	COG2860	membrane
CXX37_RS16000	COG1561	YicC-like family, N-terminal region
CXX37_RS16025	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CXX37_RS16055	COG1519	Transferase
CXX37_RS16060	COG0859	PFAM glycosyl transferase family 9
CXX37_RS16065	COG0438	transferase activity, transferring glycosyl groups
CXX37_RS16070	COG0515	serine threonine protein kinase
CXX37_RS16085	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CXX37_RS16090	COG1442	glycosyl transferase family 8
CXX37_RS16105	COG0859	PFAM glycosyl transferase family 9
CXX37_RS16110	COG0859	PFAM glycosyl transferase family 9
CXX37_RS16120	COG0156	8-amino-7-oxononanoate synthase activity
CXX37_RS16130	COG1216	Glycosyl transferase, family 2
CXX37_RS16135	COG2861	carbohydrate metabolic process
CXX37_RS16140	COG4942	peptidase
CXX37_RS16155	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CXX37_RS16160	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CXX37_RS16175	COG1045	serine acetyltransferase
CXX37_RS16180	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CXX37_RS16190	COG2186	Transcriptional regulator
CXX37_RS16195	COG1620	l-lactate permease
CXX37_RS16200	COG5295	Hep Hag repeat protein
CXX37_RS16225	COG3722	fumarate hydratase activity
CXX37_RS16235	COG2213	PTS system mannitol-specific
CXX37_RS16235	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX37_RS16245	COG1566	PFAM secretion protein HlyD family protein
CXX37_RS16265	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CXX37_RS16270	COG3209	COG3209 Rhs family protein
CXX37_RS16280	COG1413	lyase activity
CXX37_RS16290	COG3385	transposase activity
CXX37_RS16295	COG3209	COG3209 Rhs family protein
CXX37_RS16300	COG0625	glutathione transferase activity
CXX37_RS16310	COG3276	selenocysteine insertion sequence binding
CXX37_RS16315	COG1454	alcohol dehydrogenase
CXX37_RS16320	COG1012	belongs to the aldehyde dehydrogenase family
CXX37_RS16335	COG1566	PFAM secretion protein HlyD family protein
CXX37_RS16340	COG0583	DNA-binding transcription factor activity
CXX37_RS16345	COG3713	MltA-interacting MipA family protein
CXX37_RS16355	COG0235	Class ii aldolase
CXX37_RS16360	COG3623	hexulose-6-phosphate isomerase
CXX37_RS16365	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CXX37_RS16370	COG1070	Carbohydrate kinase
CXX37_RS16375	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CXX37_RS16380	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CXX37_RS16385	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CXX37_RS16390	COG2731	YhcH YjgK YiaL family protein
CXX37_RS16400	COG1414	Transcriptional regulator
CXX37_RS16405	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CXX37_RS16410	COG3977	Valine--pyruvate aminotransferase
CXX37_RS16415	COG0366	Alpha amylase catalytic
CXX37_RS16420	COG2992	FlgJ-related protein
CXX37_RS16425	COG2207	Transcriptional regulator
CXX37_RS16425	COG1609	Transcriptional regulator
CXX37_RS16430	COG4214	carbohydrate transport
CXX37_RS16435	COG1129	ABC transporter
CXX37_RS16440	COG4213	ABC transporter substrate-binding protein
CXX37_RS16450	COG1070	Carbohydrate kinase
CXX37_RS16460	COG4682	membrane
CXX37_RS16465	COG3274	enterobacterial common antigen metabolic process
CXX37_RS16495	COG1278	Cold shock
CXX37_RS16500	COG2944	sequence-specific DNA binding
CXX37_RS16515	COG2885	chlorophyll binding
CXX37_RS16520	COG0243	molybdopterin cofactor binding
CXX37_RS16525	COG0456	acetyltransferase
CXX37_RS16530	COG2818	Glycosylase
CXX37_RS16535	COG5571	outer membrane autotransporter
CXX37_RS16540	COG2223	nitrite transmembrane transporter activity
CXX37_RS16545	COG2194	sulfuric ester hydrolase activity
CXX37_RS16555	COG0747	negative chemotaxis
CXX37_RS16565	COG0601	transmembrane transport
CXX37_RS16570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CXX37_RS16575	COG0444	Belongs to the ABC transporter superfamily
CXX37_RS16580	COG4608	Belongs to the ABC transporter superfamily
CXX37_RS16585	COG0814	amino acid
CXX37_RS16625	COG1215	transferase activity, transferring glycosyl groups
CXX37_RS16630	COG1215	transferase activity, transferring glycosyl groups
CXX37_RS16635	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CXX37_RS16640	COG3118	belongs to the thioredoxin family
CXX37_RS16640	COG0457	Tetratricopeptide repeat
CXX37_RS16645	COG2199	diguanylate cyclase activity
CXX37_RS16645	COG2200	EAL domain
CXX37_RS16655	COG0612	Peptidase, M16
CXX37_RS16665	COG2200	EAL domain
CXX37_RS16670	COG2982	Protein involved in outer membrane biogenesis
CXX37_RS16675	COG0477	Major facilitator Superfamily
CXX37_RS16680	COG1295	ribonuclease BN
CXX37_RS16685	COG0583	DNA-binding transcription factor activity
CXX37_RS16690	COG2197	response regulator
CXX37_RS16700	COG1858	cytochrome C peroxidase
CXX37_RS16705	COG0076	glutamate decarboxylase activity
CXX37_RS16715	COG2207	Transcriptional regulator
CXX37_RS16720	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CXX37_RS16725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CXX37_RS16735	COG2771	luxR family
CXX37_RS16740	COG3247	response to pH
CXX37_RS16755	COG1285	pathogenesis
CXX37_RS16760	COG2197	response regulator
CXX37_RS16765	COG3065	identical protein binding
CXX37_RS16775	COG1393	Belongs to the ArsC family
CXX37_RS16780	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CXX37_RS16785	COG0640	Transcriptional regulator
CXX37_RS16795	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CXX37_RS16800	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CXX37_RS16805	COG0339	signal peptide processing
CXX37_RS16815	COG3104	oligopeptide transport
CXX37_RS16820	COG0589	response to stress
CXX37_RS16830	COG0306	phosphate transporter
CXX37_RS16835	COG2081	HI0933 family
CXX37_RS16855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CXX37_RS16860	COG0842	Transport permease protein
CXX37_RS16860	COG1129	ABC transporter
CXX37_RS16865	COG0842	Transport permease protein
CXX37_RS16870	COG5433	transposase activity
CXX37_RS16875	COG1413	lyase activity
CXX37_RS16885	COG3209	COG3209 Rhs family protein
CXX37_RS16900	COG0444	Belongs to the ABC transporter superfamily
CXX37_RS16905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CXX37_RS16910	COG0601	transmembrane transport
CXX37_RS16915	COG0747	negative chemotaxis
CXX37_RS16920	COG2091	lysine biosynthetic process via aminoadipic acid
CXX37_RS16925	COG0628	permease
CXX37_RS16930	COG0477	Major facilitator Superfamily
CXX37_RS16940	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CXX37_RS16955	COG3714	YhhN family
CXX37_RS16965	COG3776	membrane
CXX37_RS16970	COG0742	ribosomal rna small subunit methyltransferase
CXX37_RS16975	COG0552	protein localization to endoplasmic reticulum
CXX37_RS16980	COG2884	Cell division ATP-binding protein ftsE
CXX37_RS16985	COG2177	Part of the ABC transporter FtsEX involved in
CXX37_RS16990	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CXX37_RS16995	COG0683	leucine binding
CXX37_RS17000	COG0456	acetyltransferase
CXX37_RS17005	COG0683	leucine binding
CXX37_RS17010	COG0559	Belongs to the binding-protein-dependent transport system permease family
CXX37_RS17015	COG4177	L-phenylalanine transmembrane transporter activity
CXX37_RS17020	COG0411	ABC transporter
CXX37_RS17025	COG0410	ABC transporter
CXX37_RS17030	COG1653	transport
CXX37_RS17035	COG1175	transmembrane transport
CXX37_RS17040	COG0395	ABC-type sugar transport system, permease component
CXX37_RS17045	COG3842	ATPase activity
CXX37_RS17050	COG0584	glycerophosphoryl diester phosphodiesterase
CXX37_RS17060	COG0405	Gamma-glutamyltransferase
CXX37_RS17085	COG3157	Type VI secretion system effector, Hcp
CXX37_RS17090	COG1247	-acetyltransferase
CXX37_RS17095	COG0673	inositol 2-dehydrogenase activity
CXX37_RS17100	COG1741	Belongs to the pirin family
CXX37_RS17105	COG1609	Transcriptional regulator
CXX37_RS17110	COG3265	gluconokinase activity
CXX37_RS17115	COG2610	gluconate transmembrane transporter activity
CXX37_RS17120	COG2095	MarC family integral membrane protein
CXX37_RS17125	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CXX37_RS17150	COG0058	SHG alpha-glucan phosphorylase activity
CXX37_RS17155	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CXX37_RS17175	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CXX37_RS17190	COG1349	DNA-binding transcription factor activity
CXX37_RS17195	COG4650	regulator
CXX37_RS17205	COG1690	Belongs to the RtcB family
CXX37_RS17220	COG0058	SHG alpha-glucan phosphorylase activity
CXX37_RS17225	COG1640	4-alpha-glucanotransferase
CXX37_RS17230	COG2610	gluconate transmembrane transporter activity
CXX37_RS17250	COG5464	transposase or invertase
CXX37_RS17260	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CXX37_RS17265	COG1918	ferrous iron import across plasma membrane
CXX37_RS17270	COG2183	response to ionizing radiation
CXX37_RS17275	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CXX37_RS17295	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CXX37_RS17305	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CXX37_RS17310	COG1011	Hydrolase
CXX37_RS17320	COG0494	nUDIX hydrolase
CXX37_RS17325	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CXX37_RS17330	COG4972	Pilus assembly protein
CXX37_RS17335	COG3166	PFAM Fimbrial assembly family protein
CXX37_RS17350	COG4796	Type ii and iii secretion system protein
CXX37_RS17365	COG3266	domain, Protein
CXX37_RS17370	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CXX37_RS17375	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CXX37_RS17380	COG0546	phosphoglycolate phosphatase activity
CXX37_RS17385	COG0180	Tryptophanyl-tRNA synthetase
CXX37_RS17395	COG2188	Transcriptional regulator
CXX37_RS17405	COG3457	Alanine racemase
CXX37_RS17410	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CXX37_RS17415	COG1735	metal-dependent hydrolase with the TIM-barrel fold
CXX37_RS17430	COG0626	cystathionine gamma-synthase activity
CXX37_RS17435	COG2188	Transcriptional regulator
CXX37_RS17440	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CXX37_RS17445	COG1082	Xylose isomerase domain protein TIM barrel
CXX37_RS17450	COG2222	sugar isomerase
CXX37_RS17455	COG0531	amino acid
CXX37_RS17470	COG2116	formate transmembrane transporter activity
CXX37_RS17475	COG2146	nitrite reductase [NAD(P)H] activity
CXX37_RS17480	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CXX37_RS17490	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CXX37_RS17500	COG2184	nucleotidyltransferase activity
CXX37_RS17505	COG0512	Glutamine amidotransferase of anthranilate synthase
CXX37_RS17510	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CXX37_RS17515	COG1289	transmembrane transporter activity
CXX37_RS17520	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CXX37_RS17525	COG1765	OsmC-like protein
CXX37_RS17530	COG3954	Phosphoribulokinase
CXX37_RS17540	COG0429	hydrolase of the alpha beta-hydrolase fold
CXX37_RS17545	COG0488	(ABC) transporter
CXX37_RS17560	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CXX37_RS17565	COG1047	Peptidyl-prolyl cis-trans
CXX37_RS17575	COG0545	Peptidyl-prolyl cis-trans isomerase
CXX37_RS17580	COG2964	Protein conserved in bacteria
CXX37_RS17620	COG3979	chitinase
CXX37_RS17625	COG2906	2 iron, 2 sulfur cluster binding
CXX37_RS17630	COG2193	ferroxidase activity
CXX37_RS17635	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CXX37_RS17640	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CXX37_RS17645	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CXX37_RS17650	COG3156	type II secretion system protein K
CXX37_RS17655	COG4795	General secretion pathway protein
CXX37_RS17660	COG2165	general secretion pathway protein
CXX37_RS17665	COG2165	general secretion pathway protein
CXX37_RS17670	COG2165	general secretion pathway protein
CXX37_RS17680	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CXX37_RS17685	COG1450	Type ii and iii secretion system protein
CXX37_RS17690	COG3031	protein transport across the cell outer membrane
CXX37_RS17695	COG3409	Peptidoglycan-binding domain 1 protein
CXX37_RS17695	COG3267	Type II secretory pathway component ExeA
CXX37_RS17720	COG0089	rRNA binding
CXX37_RS17810	COG0201	protein transport
CXX37_RS17850	COG0789	Transcriptional regulator
CXX37_RS17855	COG3036	rescue of stalled ribosome
CXX37_RS17865	COG0569	domain protein
CXX37_RS17885	COG0758	DNA mediated transformation
CXX37_RS17895	COG0551	DNA topoisomerase type I activity
CXX37_RS17915	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CXX37_RS17955	COG1126	abc transporter atp-binding protein
CXX37_RS17960	COG0765	amino acid transport
CXX37_RS17965	COG4597	amino acid ABC transporter
CXX37_RS17970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXX37_RS17980	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CXX37_RS17985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CXX37_RS17990	COG1309	transcriptional regulator
CXX37_RS18000	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CXX37_RS18010	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CXX37_RS18020	COG4145	pantothenate transmembrane transporter activity
CXX37_RS18025	COG3924	membrane
CXX37_RS18030	COG0439	Biotin carboxylase
CXX37_RS18035	COG0511	ligase activity, forming carbon-carbon bonds
CXX37_RS18040	COG0604	alcohol dehydrogenase
CXX37_RS18045	COG2200	EAL domain
CXX37_RS18045	COG2199	diguanylate cyclase activity
CXX37_RS18055	COG1077	Cell shape determining protein MreB Mrl
CXX37_RS18060	COG1792	Involved in formation and maintenance of cell shape
CXX37_RS18065	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CXX37_RS18075	COG1530	ribonuclease E activity
CXX37_RS18080	COG3164	Protein of unknown function
CXX37_RS18085	COG0312	modulator of DNA gyrase
CXX37_RS18090	COG0583	DNA-binding transcription factor activity
CXX37_RS18110	COG2732	(Barnase) inhibitor
CXX37_RS18130	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CXX37_RS18135	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CXX37_RS18140	COG3105	Protein conserved in bacteria
CXX37_RS18145	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CXX37_RS18160	COG0625	glutathione transferase activity
CXX37_RS18165	COG2969	positive regulation of protein catabolic process
CXX37_RS18170	COG3069	C4-dicarboxylate transmembrane transporter activity
CXX37_RS18200	COG2731	YhcH YjgK YiaL family protein
CXX37_RS18220	COG0493	'glutamate synthase
CXX37_RS18225	COG0070	glutamate synthase
CXX37_RS18225	COG0069	glutamate synthase activity
CXX37_RS18225	COG0067	glutamate synthase
CXX37_RS18230	COG1242	4 iron, 4 sulfur cluster binding
CXX37_RS18235	COG0784	Response regulator, receiver
CXX37_RS18235	COG5002	protein histidine kinase activity
CXX37_RS18235	COG2198	Histidine kinase
CXX37_RS18240	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CXX37_RS18250	COG0515	serine threonine protein kinase
CXX37_RS18260	COG3436	PFAM IS66 Orf2 family protein
CXX37_RS18265	COG4372	Transposase
CXX37_RS18270	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX37_RS18285	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CXX37_RS18290	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CXX37_RS18295	COG1137	ATPase activity
CXX37_RS18300	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CXX37_RS18305	COG3117	lipopolysaccharide transmembrane transporter activity
CXX37_RS18310	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CXX37_RS18315	COG0517	IMP dehydrogenase activity
CXX37_RS18315	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CXX37_RS18320	COG0530	calcium, potassium:sodium antiporter activity
CXX37_RS18325	COG1127	ABC transporter
CXX37_RS18330	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CXX37_RS18335	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CXX37_RS18340	COG2854	intermembrane phospholipid transfer
CXX37_RS18345	COG3113	response to antibiotic
CXX37_RS18350	COG5007	Belongs to the BolA IbaG family
CXX37_RS18360	COG3423	Transcriptional regulator
CXX37_RS18365	COG0142	geranyltranstransferase activity
CXX37_RS18380	COG0697	spore germination
CXX37_RS18390	COG2027	D-alanyl-D-alanine carboxypeptidase
CXX37_RS18395	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CXX37_RS18400	COG1534	Rna-binding protein
CXX37_RS18410	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CXX37_RS18415	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CXX37_RS18425	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CXX37_RS18465	COG0195	Participates in both transcription termination and antitermination
CXX37_RS18505	COG0513	Belongs to the DEAD box helicase family
CXX37_RS18510	COG0814	amino acid
CXX37_RS18515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CXX37_RS18520	COG0826	peptidase U32
CXX37_RS18525	COG0826	peptidase U32
CXX37_RS18530	COG3154	lipid carrier protein
CXX37_RS18535	COG3153	acetyltransferase
CXX37_RS18550	COG0693	protein deglycase activity
CXX37_RS18555	COG0702	epimerase
CXX37_RS18560	COG0701	Predicted permease
CXX37_RS18565	COG2823	Periplasmic or secreted lipoprotein
CXX37_RS18580	COG3107	peptidoglycan biosynthetic process
CXX37_RS18585	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CXX37_RS18590	COG3539	Fimbrial protein
CXX37_RS18600	COG4372	Transposase
CXX37_RS18605	COG3436	PFAM IS66 Orf2 family protein
CXX37_RS18615	COG3188	usher protein
CXX37_RS18630	COG3121	Chaperone
CXX37_RS18635	COG3539	Fimbrial protein
CXX37_RS18640	COG0363	glucosamine-6-phosphate deaminase activity
CXX37_RS18645	COG3716	PTS system mannose fructose sorbose family IID component
CXX37_RS18650	COG3715	PTS system
CXX37_RS18655	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXX37_RS18665	COG2222	sugar isomerase
CXX37_RS18670	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CXX37_RS18675	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX37_RS18680	COG3716	PTS system mannose fructose sorbose family IID component
CXX37_RS18690	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXX37_RS18700	COG1349	DNA-binding transcription factor activity
CXX37_RS18710	COG2002	toxin-antitoxin pair type II binding
CXX37_RS18715	COG2721	sulfolactate sulfo-lyase activity
CXX37_RS18720	COG2271	Major facilitator Superfamily
CXX37_RS18730	COG2084	Dehydrogenase
CXX37_RS18735	COG1929	Belongs to the glycerate kinase type-1 family
CXX37_RS18760	COG0583	DNA-binding transcription factor activity
CXX37_RS18765	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CXX37_RS18775	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CXX37_RS18780	COG1882	Formate acetyltransferase
CXX37_RS18785	COG0251	oxidation-reduction process
CXX37_RS18790	COG1760	l-serine dehydratase
CXX37_RS18795	COG0814	amino acid
CXX37_RS18805	COG1741	Belongs to the pirin family
CXX37_RS18810	COG0583	DNA-binding transcription factor activity
CXX37_RS18815	COG3152	Membrane
CXX37_RS18820	COG3152	Membrane
CXX37_RS18825	COG0435	Glutathione S-transferase
CXX37_RS18830	COG2259	Doxx family
CXX37_RS18840	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CXX37_RS18845	COG4575	ribosome binding
CXX37_RS18850	COG1422	Protein of unknown function (DUF1090)
CXX37_RS18860	COG0586	Pfam SNARE associated Golgi protein
CXX37_RS18865	COG2186	Transcriptional regulator
CXX37_RS18870	COG2271	Major facilitator Superfamily
CXX37_RS18880	COG2721	sulfolactate sulfo-lyase activity
CXX37_RS18890	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CXX37_RS18895	COG0861	Integral membrane protein TerC family
CXX37_RS18900	COG0673	inositol 2-dehydrogenase activity
CXX37_RS18905	COG2949	membrane
CXX37_RS18910	COG1451	nucleotide metabolic process
CXX37_RS18920	COG4680	protein conserved in bacteria
CXX37_RS18925	COG5499	transcription regulator containing HTH domain
CXX37_RS18930	COG0446	pyridine nucleotide-disulphide oxidoreductase
CXX37_RS18930	COG1902	pentaerythritol trinitrate reductase activity
CXX37_RS18935	COG3408	Glycogen debranching enzyme
CXX37_RS18935	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
CXX37_RS18945	COG0531	amino acid
CXX37_RS18950	COG2731	YhcH YjgK YiaL family protein
CXX37_RS18955	COG3250	beta-galactosidase activity
CXX37_RS18960	COG1609	Transcriptional regulator
CXX37_RS18965	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CXX37_RS18975	COG0840	transmembrane signaling receptor activity
CXX37_RS18980	COG1695	Transcriptional regulator
CXX37_RS18985	COG2375	cellular response to nickel ion
CXX37_RS19000	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CXX37_RS19005	COG0358	DNA primase activity
CXX37_RS19010	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CXX37_RS19020	COG0471	metal ion transport
CXX37_RS19025	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CXX37_RS19030	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CXX37_RS19035	COG0583	DNA-binding transcription factor activity
CXX37_RS19045	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CXX37_RS19060	COG4991	sh3 domain protein
CXX37_RS19065	COG3025	triphosphatase activity
CXX37_RS19090	COG2268	Band 7 protein
CXX37_RS19095	COG1585	Membrane protein implicated in regulation of membrane protease activity
CXX37_RS19105	COG3539	Fimbrial protein
CXX37_RS19110	COG3121	Chaperone
CXX37_RS19130	COG3539	Fimbrial protein
CXX37_RS19135	COG2960	long-chain fatty acid transporting porin activity
CXX37_RS19150	COG3384	dioxygenase
CXX37_RS19155	COG0754	glutathionylspermidine amidase activity
CXX37_RS19165	COG1538	Outer membrane efflux protein
CXX37_RS19170	COG0494	nUDIX hydrolase
CXX37_RS19175	COG3151	Protein conserved in bacteria
CXX37_RS19180	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CXX37_RS19185	COG3150	esterase
CXX37_RS19190	COG0187	DNA topoisomerase II activity
CXX37_RS19195	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CXX37_RS19200	COG2249	NAD(P)H dehydrogenase (quinone) activity
CXX37_RS19210	COG0642	Histidine kinase
CXX37_RS19215	COG0745	RESPONSE REGULATOR receiver
CXX37_RS19220	COG3111	PFAM Bacterial OB fold (BOF) protein
CXX37_RS19225	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CXX37_RS19235	COG2944	sequence-specific DNA binding
CXX37_RS19240	COG4166	transmembrane transport
CXX37_RS19245	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CXX37_RS19250	COG0204	Acyl-transferase
CXX37_RS19255	COG2132	Multicopper oxidase
CXX37_RS19260	COG1032	radical SAM domain protein
CXX37_RS19265	COG4238	major outer membrane lipoprotein
CXX37_RS19275	COG0656	L-ascorbic acid biosynthetic process
CXX37_RS19280	COG1979	alcohol dehydrogenase
CXX37_RS19285	COG2207	Transcriptional regulator
CXX37_RS19290	COG0586	Pfam SNARE associated Golgi protein
CXX37_RS19295	COG0626	cystathionine gamma-synthase activity
CXX37_RS19300	COG0811	peptide transport
CXX37_RS19305	COG0848	biopolymer transport protein
CXX37_RS19310	COG1028	Short-chain dehydrogenase reductase Sdr
CXX37_RS19320	COG0667	Aldo Keto reductase
CXX37_RS19335	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CXX37_RS19340	COG0437	4 iron, 4 sulfur cluster binding
CXX37_RS19345	COG5557	Pfam Polysulphide reductase, NrfD
CXX37_RS19350	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CXX37_RS19355	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CXX37_RS19360	COG1773	rubredoxin
CXX37_RS19370	COG0298	carbon dioxide binding
CXX37_RS19375	COG0625	glutathione transferase activity
CXX37_RS19380	COG0754	glutathionylspermidine amidase activity
CXX37_RS19385	COG0306	phosphate transporter
CXX37_RS19390	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CXX37_RS19395	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CXX37_RS19400	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CXX37_RS19405	COG2244	polysaccharide biosynthetic process
CXX37_RS19415	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CXX37_RS19420	COG0795	lipopolysaccharide-transporting ATPase activity
CXX37_RS19430	COG0156	8-amino-7-oxononanoate synthase activity
CXX37_RS19435	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CXX37_RS19445	COG0318	PFAM AMP-dependent synthetase and ligase
CXX37_RS19450	COG0456	acetyltransferase
CXX37_RS19455	COG2186	Transcriptional regulator
CXX37_RS19460	COG0277	FAD linked oxidase domain protein
CXX37_RS19465	COG0277	FAD linked oxidase domain protein
CXX37_RS19470	COG0247	lactate metabolic process
CXX37_RS19475	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CXX37_RS19480	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CXX37_RS19485	COG1620	l-lactate permease
CXX37_RS19490	COG3064	Membrane
CXX37_RS19520	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CXX37_RS19525	COG1459	type II secretion system
CXX37_RS19530	COG2165	general secretion pathway protein
CXX37_RS19560	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CXX37_RS19570	COG1811	Na channel or pump
CXX37_RS19575	COG1982	Orn Lys Arg decarboxylase major
CXX37_RS19580	COG2211	Major facilitator Superfamily
CXX37_RS19595	COG1194	a g-specific adenine glycosylase
CXX37_RS19605	COG3171	Protein conserved in bacteria
CXX37_RS19615	COG0252	asparaginase activity
CXX37_RS19625	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CXX37_RS19630	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CXX37_RS19640	COG0762	integral membrane protein
CXX37_RS19645	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CXX37_RS19650	COG2805	Type II/IV secretion system protein
CXX37_RS19665	COG0189	ligase activity
CXX37_RS19670	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CXX37_RS19675	COG2356	endonuclease I
CXX37_RS19685	COG2814	Major facilitator Superfamily
CXX37_RS19710	COG1166	arginine decarboxylase activity
CXX37_RS19720	COG0501	Belongs to the peptidase M48B family
CXX37_RS19725	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CXX37_RS19730	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX37_RS19735	COG2213	PTS system mannitol-specific
CXX37_RS19745	COG1494	fructose-1,6-bisphosphatase
CXX37_RS19750	COG3722	fumarate hydratase activity
CXX37_RS19755	COG1072	(Pantothenic acid kinase))
CXX37_RS19770	COG0191	fructose-bisphosphate aldolase activity
CXX37_RS19775	COG0668	transmembrane transport
CXX37_RS19780	COG1279	arginine transmembrane transporter activity
CXX37_RS19785	COG2968	Membrane
CXX37_RS19790	COG0583	DNA-binding transcription factor activity
CXX37_RS19795	COG0427	acetyl-CoA hydrolase
CXX37_RS19800	COG1024	Enoyl-CoA hydratase
CXX37_RS19805	COG1703	isobutyryl-CoA mutase activity
CXX37_RS19810	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CXX37_RS19810	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CXX37_RS19830	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CXX37_RS19840	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CXX37_RS19860	COG0006	proline dipeptidase activity
CXX37_RS19865	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CXX37_RS19870	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CXX37_RS19895	COG1028	Short-chain dehydrogenase reductase Sdr
CXX37_RS19900	COG2723	6-phospho-beta-galactosidase activity
CXX37_RS19910	COG1272	protein, Hemolysin III
CXX37_RS19920	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CXX37_RS19930	COG0716	FMN binding
CXX37_RS19935	COG4974	Belongs to the 'phage' integrase family
CXX37_RS19940	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CXX37_RS19945	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CXX37_RS19955	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CXX37_RS19985	COG4942	peptidase
CXX37_RS20085	COG0457	Tetratricopeptide repeat
CXX37_RS20085	COG3710	Transcriptional regulator
CXX37_RS20090	COG0457	Tetratricopeptide repeat
CXX37_RS20115	COG3710	Transcriptional regulator
CXX37_RS20120	COG2771	luxR family
CXX37_RS20125	COG0814	amino acid
CXX37_RS20130	COG0183	Belongs to the thiolase family
CXX37_RS20140	COG1028	Short-chain dehydrogenase reductase Sdr
CXX37_RS20145	COG2814	Major facilitator Superfamily
CXX37_RS20150	COG1794	racemase activity, acting on amino acids and derivatives
CXX37_RS20155	COG0583	DNA-binding transcription factor activity
CXX37_RS20165	COG1609	Transcriptional regulator
CXX37_RS20180	COG0667	Aldo Keto reductase
CXX37_RS20190	COG0861	Integral membrane protein TerC family
CXX37_RS20210	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
CXX37_RS20225	COG2165	general secretion pathway protein
CXX37_RS20230	COG4795	General secretion pathway protein
CXX37_RS20240	COG4967	type IV pilus modification protein PilV
CXX37_RS20245	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CXX37_RS20250	COG1025	Belongs to the peptidase M16 family
CXX37_RS20255	COG1074	ATP-dependent DNA helicase activity
CXX37_RS20260	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CXX37_RS20265	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CXX37_RS20265	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CXX37_RS20270	COG0860	N-Acetylmuramoyl-L-alanine amidase
CXX37_RS20290	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CXX37_RS20295	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CXX37_RS20300	COG2166	iron-sulfur cluster assembly
CXX37_RS20305	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CXX37_RS20315	COG0583	DNA-binding transcription factor activity
CXX37_RS20320	COG2363	Small membrane protein
CXX37_RS20330	COG1349	DNA-binding transcription factor activity
CXX37_RS20340	COG1070	Carbohydrate kinase
CXX37_RS20350	COG0738	Major facilitator superfamily
CXX37_RS20355	COG0235	Class ii aldolase
CXX37_RS20360	COG1454	alcohol dehydrogenase
CXX37_RS20370	COG1760	l-serine dehydratase
CXX37_RS20375	COG0814	amino acid
CXX37_RS20380	COG1611	Belongs to the LOG family
CXX37_RS20395	COG3098	single-species biofilm formation
CXX37_RS20400	COG0564	pseudouridine synthase activity
CXX37_RS20405	COG0716	FMN binding
CXX37_RS20410	COG2271	Major facilitator Superfamily
CXX37_RS20415	COG4948	Mandelate Racemase Muconate Lactonizing
CXX37_RS20420	COG4948	Mandelate Racemase Muconate Lactonizing
CXX37_RS20425	COG3850	Histidine kinase
CXX37_RS20425	COG2205	protein histidine kinase activity
CXX37_RS20425	COG4999	Histidine kinase
CXX37_RS20425	COG3437	response regulator, receiver
CXX37_RS20430	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CXX37_RS20435	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CXX37_RS20440	COG2336	PFAM SpoVT AbrB
CXX37_RS20445	COG2337	Toxic component of a toxin-antitoxin (TA) module
CXX37_RS20450	COG3956	TIGRFAM MazG family protein
CXX37_RS20465	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CXX37_RS20475	COG0602	queuosine metabolic process
CXX37_RS20485	COG1070	Carbohydrate kinase
CXX37_RS20490	COG2223	nitrite transmembrane transporter activity
CXX37_RS20505	COG0477	Major facilitator Superfamily
CXX37_RS20510	COG2086	electron transfer activity
CXX37_RS20515	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CXX37_RS20520	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CXX37_RS20525	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CXX37_RS20530	COG0644	oxidoreductase
CXX37_RS20535	COG0720	synthase
CXX37_RS20545	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CXX37_RS20565	COG3385	transposase activity
CXX37_RS20570	COG1203	CRISPR-associated helicase, Cas3
CXX37_RS20585	COG1857	crispr-associated protein
CXX37_RS20600	COG1518	maintenance of DNA repeat elements
CXX37_RS20605	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CXX37_RS20610	COG2234	aminopeptidase activity
CXX37_RS20665	COG4942	peptidase
CXX37_RS20665	COG1388	LysM domain
CXX37_RS20670	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CXX37_RS20675	COG2610	gluconate transmembrane transporter activity
CXX37_RS20680	COG3622	Belongs to the hyi family
CXX37_RS20690	COG3395	kinase activity
CXX37_RS20695	COG2084	Dehydrogenase
CXX37_RS20700	COG1349	DNA-binding transcription factor activity
CXX37_RS20705	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CXX37_RS20725	COG3604	Transcriptional regulator
CXX37_RS20730	COG0309	Hydrogenase expression formation protein (HypE)
CXX37_RS20735	COG0409	Hydrogenase expression formation protein
CXX37_RS20740	COG0298	carbon dioxide binding
CXX37_RS20745	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CXX37_RS20750	COG0375	protein maturation
CXX37_RS20765	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CXX37_RS20770	COG0651	ATP synthesis coupled electron transport
CXX37_RS20775	COG0650	Formate hydrogenlyase subunit 4
CXX37_RS20780	COG3261	NADH dehydrogenase
CXX37_RS20780	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CXX37_RS20785	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CXX37_RS20790	COG3260	NADH ubiquinone oxidoreductase 20
CXX37_RS20800	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CXX37_RS20805	COG2723	6-phospho-beta-galactosidase activity
CXX37_RS20810	COG1263	PTS System
CXX37_RS20810	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXX37_RS20815	COG1609	Transcriptional regulator
CXX37_RS20820	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CXX37_RS20825	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CXX37_RS20850	COG1349	DNA-binding transcription factor activity
CXX37_RS20855	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX37_RS20860	COG1028	Short-chain dehydrogenase reductase Sdr
CXX37_RS20865	COG3731	PTS system glucitol sorbitol-specific IIA component
CXX37_RS20870	COG3732	PTS system glucitol sorbitol-specific
CXX37_RS20875	COG3730	PTS system glucitol sorbitol-specific
CXX37_RS20880	COG2951	lytic endotransglycosylase activity
CXX37_RS20885	COG1546	Belongs to the CinA family
CXX37_RS20905	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CXX37_RS20935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CXX37_RS20940	COG1238	metal cluster binding
CXX37_RS20955	COG2814	Major facilitator Superfamily
CXX37_RS20960	COG1566	PFAM secretion protein HlyD family protein
CXX37_RS20965	COG1846	Transcriptional regulator
CXX37_RS20975	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CXX37_RS20980	COG2814	Major facilitator Superfamily
CXX37_RS20985	COG2113	Glycine betaine
CXX37_RS20990	COG4176	ABC-type proline glycine betaine transport system permease component
CXX37_RS20995	COG4175	Glycine betaine
CXX37_RS21005	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CXX37_RS21010	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CXX37_RS21020	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CXX37_RS21025	COG4575	ribosome binding
CXX37_RS21040	COG2916	Histone family protein nucleoid-structuring protein H-NS
CXX37_RS21045	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CXX37_RS21050	COG0640	Transcriptional regulator
CXX37_RS21055	COG0401	homolog of Blt101
CXX37_RS21060	COG1652	LysM domain
CXX37_RS21065	COG1802	Transcriptional regulator
CXX37_RS21070	COG1113	amino acid transport
CXX37_RS21075	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CXX37_RS21080	COG1012	belongs to the aldehyde dehydrogenase family
CXX37_RS21085	COG0579	oxidoreductase
CXX37_RS21100	COG0366	Alpha amylase catalytic
CXX37_RS21125	COG3468	outer membrane autotransporter barrel domain protein
CXX37_RS21140	COG2867	negative regulation of translational initiation
CXX37_RS21150	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CXX37_RS21155	COG0497	DNA recombination
CXX37_RS21175	COG4536	flavin adenine dinucleotide binding
CXX37_RS21180	COG4137	Cytochrome C assembly protein
CXX37_RS21185	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CXX37_RS21210	COG2885	chlorophyll binding
CXX37_RS21215	COG2199	diguanylate cyclase activity
CXX37_RS21245	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CXX37_RS21250	COG0287	Prephenate dehydrogenase
CXX37_RS21250	COG1605	Chorismate mutase
CXX37_RS21255	COG0077	Prephenate dehydratase
CXX37_RS21255	COG1605	Chorismate mutase
CXX37_RS21265	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CXX37_RS21270	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CXX37_RS21275	COG0564	pseudouridine synthase activity
CXX37_RS21280	COG1496	oxidoreductase activity
CXX37_RS21285	COG0542	response to heat
CXX37_RS21310	COG0477	Major facilitator Superfamily
CXX37_RS21315	COG5544	Lipoprotein
CXX37_RS21320	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CXX37_RS21325	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CXX37_RS21325	COG0045	succinate-CoA ligase (ADP-forming) activity
CXX37_RS21325	COG1042	CoA-binding domain protein
CXX37_RS21330	COG3148	PFAM DTW domain containing protein
CXX37_RS21335	COG3118	belongs to the thioredoxin family
CXX37_RS21340	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CXX37_RS21360	COG0583	DNA-binding transcription factor activity
CXX37_RS21365	COG0513	Belongs to the DEAD box helicase family
CXX37_RS21375	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CXX37_RS21385	COG1595	DNA-templated transcription, initiation
CXX37_RS21390	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
CXX37_RS21395	COG3026	antisigma factor binding
CXX37_RS21400	COG3086	response to oxidative stress
CXX37_RS21410	COG0681	Belongs to the peptidase S26 family
CXX37_RS21430	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CXX37_RS21445	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CXX37_RS21450	COG1737	Transcriptional regulator
CXX37_RS21455	COG0560	Phosphoserine phosphatase
CXX37_RS21470	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CXX37_RS21470	COG0047	phosphoribosylformylglycinamidine synthase activity
CXX37_RS21490	COG3170	Tfp pilus assembly protein FimV
CXX37_RS21495	COG2204	response regulator
CXX37_RS21500	COG0347	Belongs to the P(II) protein family
CXX37_RS21505	COG1017	nitric oxide dioxygenase activity
CXX37_RS21505	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CXX37_RS21515	COG1940	carbohydrate kinase activity
CXX37_RS21520	COG0457	Tetratricopeptide repeat
CXX37_RS21525	COG1879	ABC-type sugar transport system periplasmic component
CXX37_RS21530	COG1129	ABC transporter
CXX37_RS21535	COG1172	Belongs to the binding-protein-dependent transport system permease family
CXX37_RS21540	COG1063	alcohol dehydrogenase
CXX37_RS21545	COG2017	converts alpha-aldose to the beta-anomer
CXX37_RS21550	COG2259	Doxx family
CXX37_RS21575	COG4638	Rieske (2fe-2S)
CXX37_RS21580	COG0583	DNA-binding transcription factor activity
CXX37_RS21585	COG2814	Major facilitator Superfamily
CXX37_RS21590	COG3711	transcriptional antiterminator
CXX37_RS21595	COG1073	alpha beta
CXX37_RS21600	COG0483	inositol monophosphate 1-phosphatase activity
CXX37_RS21620	COG0822	iron-sulfur transferase activity
CXX37_RS21640	COG0633	Ferredoxin
CXX37_RS21645	COG2975	iron-sulfur cluster assembly
CXX37_RS21660	COG2897	thiosulfate sulfurtransferase activity
CXX37_RS21665	COG2373	Large extracellular alpha-helical protein
CXX37_RS21670	COG4953	penicillin-binding protein 1C
CXX37_RS21700	COG2976	Protein conserved in bacteria
CXX37_RS21715	COG1645	bacterial-type flagellum-dependent swarming motility
CXX37_RS21725	COG0517	IMP dehydrogenase activity
CXX37_RS21725	COG0516	GMP reductase activity
CXX37_RS21740	COG3133	Outer membrane lipoprotein
CXX37_RS21750	COG2200	EAL domain
CXX37_RS21755	COG0248	Ppx GppA phosphatase
CXX37_RS21760	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CXX37_RS21765	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CXX37_RS21780	COG2233	PERMEase
CXX37_RS21790	COG1393	Belongs to the ArsC family
CXX37_RS21795	COG4783	chaperone-mediated protein folding
CXX37_RS21800	COG0628	permease
CXX37_RS21805	COG2116	formate transmembrane transporter activity
CXX37_RS21810	COG3604	Transcriptional regulator
CXX37_RS21820	COG3260	NADH ubiquinone oxidoreductase 20
CXX37_RS21825	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CXX37_RS21830	COG3261	NADH dehydrogenase
CXX37_RS21830	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CXX37_RS21835	COG0651	ATP synthesis coupled electron transport
CXX37_RS21840	COG4237	Hydrogenase 4 membrane
CXX37_RS21845	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CXX37_RS21850	COG0650	Formate hydrogenlyase subunit 4
CXX37_RS21860	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CXX37_RS21865	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CXX37_RS21870	COG2716	regulation of RNA biosynthetic process
CXX37_RS21880	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CXX37_RS21890	COG2321	neutral zinc metallopeptidase
CXX37_RS21895	COG1444	tRNA N-acetyltransferase activity
CXX37_RS21900	COG0400	carboxylic ester hydrolase activity
CXX37_RS21915	COG1393	Belongs to the ArsC family
CXX37_RS21925	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CXX37_RS21930	COG3850	Histidine kinase
CXX37_RS21935	COG0493	'glutamate synthase
CXX37_RS21935	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CXX37_RS21945	COG5342	invasion associated locus B
CXX37_RS21950	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CXX37_RS21955	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CXX37_RS21960	COG0280	phosphate acetyltransferase
CXX37_RS21960	COG0281	malic enzyme
CXX37_RS21965	COG4810	utilization protein
CXX37_RS21970	COG4917	ethanolamine utilization protein
CXX37_RS21975	COG4766	ethanolamine catabolic process
CXX37_RS21980	COG4812	Cobalamin adenosyltransferase
CXX37_RS21985	COG0280	phosphate acetyltransferase
CXX37_RS21990	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CXX37_RS21995	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
CXX37_RS22000	COG1012	belongs to the aldehyde dehydrogenase family
CXX37_RS22005	COG4820	ethanolamine utilization protein (EutJ)
CXX37_RS22010	COG1454	alcohol dehydrogenase
CXX37_RS22015	COG3192	ethanolamine utilization protein
CXX37_RS22020	COG4819	ethanolamine utilization protein
CXX37_RS22025	COG4303	Ethanolamine ammonia lyase large subunit
CXX37_RS22035	COG4816	utilization protein
CXX37_RS22040	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CXX37_RS22055	COG0860	N-Acetylmuramoyl-L-alanine amidase
CXX37_RS22060	COG0456	acetyltransferase
CXX37_RS22075	COG2837	iron assimilation
CXX37_RS22080	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CXX37_RS22085	COG1263	PTS System
CXX37_RS22085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXX37_RS22100	COG1028	Short-chain dehydrogenase reductase Sdr
CXX37_RS22105	COG4150	thiosulfate binding
CXX37_RS22110	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CXX37_RS22115	COG4208	sulfate ABC transporter
CXX37_RS22120	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CXX37_RS22125	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CXX37_RS22130	COG3831	ATPase activity
CXX37_RS22130	COG4884	unkown
CXX37_RS22145	COG2190	(PTS) system
CXX37_RS22150	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CXX37_RS22155	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX37_RS22160	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CXX37_RS22180	COG3530	Putative quorum-sensing-regulated virulence factor
CXX37_RS22185	COG0385	Bile acid
CXX37_RS22190	COG0583	DNA-binding transcription factor activity
CXX37_RS22200	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CXX37_RS22205	COG2211	Major facilitator Superfamily
CXX37_RS22215	COG0583	DNA-binding transcription factor activity
CXX37_RS22245	COG3415	Transposase
CXX37_RS22250	COG3415	Transposase
CXX37_RS22270	COG3039	Transposase
CXX37_RS22280	COG3385	transposase activity
CXX37_RS22285	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CXX37_RS22310	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CXX37_RS22315	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CXX37_RS22320	COG0006	proline dipeptidase activity
CXX37_RS22325	COG1363	Peptidase, m42
CXX37_RS22330	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX37_RS22330	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CXX37_RS22330	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX37_RS22335	COG2207	Transcriptional regulator
CXX37_RS22340	COG3279	Response regulator of the LytR AlgR family
CXX37_RS22345	COG3275	phosphorelay sensor kinase activity
CXX37_RS22350	COG0436	Aminotransferase
CXX37_RS22360	COG1560	Kdo2-lipid A biosynthetic process
CXX37_RS22390	COG0028	Belongs to the TPP enzyme family
CXX37_RS22395	COG0679	Auxin Efflux Carrier
CXX37_RS22400	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CXX37_RS22405	COG2198	Histidine kinase
CXX37_RS22405	COG2205	protein histidine kinase activity
CXX37_RS22405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXX37_RS22405	COG0784	Response regulator, receiver
CXX37_RS22410	COG2197	response regulator
CXX37_RS22415	COG1566	PFAM secretion protein HlyD family protein
CXX37_RS22420	COG0477	Major facilitator Superfamily
CXX37_RS22430	COG2610	gluconate transmembrane transporter activity
CXX37_RS22435	COG0583	DNA-binding transcription factor activity
CXX37_RS22475	COG3299	homolog of phage Mu protein gp47
CXX37_RS22480	COG3778	Protein conserved in bacteria
CXX37_RS22500	COG2116	formate transmembrane transporter activity
CXX37_RS22505	COG2853	Lipoprotein
CXX37_RS22515	COG2067	long-chain fatty acid transport protein
CXX37_RS22520	COG3691	Protein conserved in bacteria
CXX37_RS22535	COG2062	phosphohistidine phosphatase, SixA
CXX37_RS22540	COG3539	Fimbrial protein
CXX37_RS22545	COG3188	usher protein
CXX37_RS22550	COG3121	Chaperone
CXX37_RS22555	COG3539	Fimbrial protein
CXX37_RS22560	COG3539	Fimbrial protein
CXX37_RS22565	COG3539	Fimbrial protein
CXX37_RS22580	COG2890	protein-(glutamine-N5) methyltransferase activity
CXX37_RS22595	COG0730	response to heat
CXX37_RS22600	COG3101	peptidyl-lysine hydroxylation
CXX37_RS22615	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CXX37_RS22620	COG2814	Major facilitator Superfamily
CXX37_RS22635	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CXX37_RS22645	COG0586	Pfam SNARE associated Golgi protein
CXX37_RS22655	COG0285	dihydrofolate synthase activity
CXX37_RS22660	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CXX37_RS22665	COG1286	toxin biosynthetic process
CXX37_RS22670	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CXX37_RS22675	COG0163	prenyltransferase activity
CXX37_RS22680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXX37_RS22685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXX37_RS22690	COG4215	(ABC) transporter
CXX37_RS22695	COG4160	amino acid transport
CXX37_RS22700	COG4598	ABC transporter
CXX37_RS22705	COG5464	transposase or invertase
CXX37_RS22710	COG1090	epimerase
CXX37_RS22715	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CXX37_RS22720	COG0625	glutathione transferase activity
CXX37_RS22725	COG0625	glutathione transferase activity
CXX37_RS22730	COG0622	Phosphoesterase
CXX37_RS22735	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CXX37_RS22740	COG1288	antiporter activity
CXX37_RS22745	COG0857	belongs to the CobB CobQ family
CXX37_RS22745	COG0280	phosphate acetyltransferase
CXX37_RS22750	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CXX37_RS22765	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CXX37_RS22770	COG0471	metal ion transport
CXX37_RS22770	COG0490	domain, Protein
CXX37_RS22780	COG0436	Aminotransferase
CXX37_RS22785	COG0583	DNA-binding transcription factor activity
CXX37_RS22805	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CXX37_RS22810	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CXX37_RS22815	COG1034	ATP synthesis coupled electron transport
CXX37_RS22830	COG0839	Belongs to the complex I subunit 6 family
CXX37_RS22840	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CXX37_RS22845	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CXX37_RS22855	COG0457	Tetratricopeptide repeat
CXX37_RS22880	COG2234	aminopeptidase activity
CXX37_RS22885	COG2304	oxidoreductase activity
CXX37_RS22900	COG2153	protein acetylation
CXX37_RS22905	COG4575	ribosome binding
CXX37_RS22910	COG1169	isochorismate synthase
CXX37_RS22925	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CXX37_RS22935	COG0318	PFAM AMP-dependent synthetase and ligase
CXX37_RS22975	COG2271	Major facilitator Superfamily
CXX37_RS22990	COG5464	transposase or invertase
CXX37_RS22995	COG0247	lactate metabolic process
CXX37_RS23005	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CXX37_RS23010	COG2271	Major facilitator Superfamily
CXX37_RS23015	COG0584	glycerophosphoryl diester phosphodiesterase
CXX37_RS23025	COG3642	lipopolysaccharide core region biosynthetic process
CXX37_RS23030	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CXX37_RS23035	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CXX37_RS23040	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CXX37_RS23060	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CXX37_RS23065	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
CXX37_RS23070	COG3234	Protein of unknown function (DUF1175)
CXX37_RS23075	COG2373	Large extracellular alpha-helical protein
CXX37_RS23080	COG5445	Predicted secreted protein (DUF2300)
CXX37_RS23085	COG4676	Protein conserved in bacteria
CXX37_RS23090	COG0183	Belongs to the thiolase family
CXX37_RS23095	COG2031	fatty acid transporter
CXX37_RS23100	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CXX37_RS23105	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CXX37_RS23110	COG2204	response regulator
CXX37_RS23120	COG0784	Response regulator, receiver
CXX37_RS23120	COG2205	protein histidine kinase activity
CXX37_RS23125	COG2197	response regulator
CXX37_RS23130	COG0642	Histidine kinase
CXX37_RS23130	COG2198	Histidine kinase
CXX37_RS23135	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CXX37_RS23140	COG1477	protein flavinylation
CXX37_RS23145	COG2169	Transcriptional regulator
CXX37_RS23145	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CXX37_RS23150	COG3145	DNA-N1-methyladenine dioxygenase activity
CXX37_RS23155	COG4615	Cyclic peptide transporter
CXX37_RS23170	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CXX37_RS23170	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
CXX37_RS23175	COG3062	negative regulation of establishment of protein localization
CXX37_RS23185	COG0437	4 iron, 4 sulfur cluster binding
CXX37_RS23190	COG0348	domain, Protein
CXX37_RS23195	COG3043	anaerobic respiration
CXX37_RS23200	COG3005	denitrification pathway
CXX37_RS23205	COG4133	protoheme IX ABC transporter activity
CXX37_RS23210	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CXX37_RS23215	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CXX37_RS23220	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CXX37_RS23230	COG1138	Cytochrome C-type biogenesis protein
CXX37_RS23235	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CXX37_RS23240	COG3088	subunit of a heme lyase
CXX37_RS23240	COG4235	cytochrome complex assembly
CXX37_RS23245	COG2197	response regulator
CXX37_RS23250	COG3468	outer membrane autotransporter barrel domain protein
CXX37_RS23260	COG3083	sulfuric ester hydrolase activity
CXX37_RS23280	COG1061	Type III restriction enzyme res subunit
CXX37_RS23285	COG1187	pseudouridine synthase activity
CXX37_RS23290	COG2814	Major facilitator Superfamily
CXX37_RS23300	COG4172	Belongs to the ABC transporter superfamily
CXX37_RS23305	COG4239	(ABC) transporter, permease
CXX37_RS23310	COG4174	ABC transporter (Permease)
CXX37_RS23315	COG4166	transmembrane transport
CXX37_RS23320	COG2200	EAL domain
CXX37_RS23325	COG0791	NLP P60 protein
CXX37_RS23330	COG0671	phosphoesterase, PA-phosphatase related
CXX37_RS23335	COG0523	cobalamin synthesis protein
CXX37_RS23340	COG0246	Mannitol dehydrogenase
CXX37_RS23355	COG2814	Major facilitator Superfamily
CXX37_RS23360	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX37_RS23360	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXX37_RS23365	COG1105	Belongs to the carbohydrate kinase PfkB family
CXX37_RS23370	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CXX37_RS23370	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CXX37_RS23370	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CXX37_RS23375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CXX37_RS23380	COG2313	pseudouridylate synthase activity
CXX37_RS23385	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CXX37_RS23390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CXX37_RS23400	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CXX37_RS23405	COG1522	sequence-specific DNA binding
CXX37_RS23405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CXX37_RS23415	COG2855	membrane
CXX37_RS23420	COG0583	DNA-binding transcription factor activity
CXX37_RS23425	COG0833	amino acid
CXX37_RS23430	COG4771	TonB-dependent receptor
CXX37_RS23445	COG2311	Membrane
CXX37_RS23450	COG1609	Transcriptional regulator
CXX37_RS23455	COG1879	ABC-type sugar transport system periplasmic component
CXX37_RS23460	COG1129	ABC transporter
CXX37_RS23465	COG4211	Belongs to the binding-protein-dependent transport system permease family
CXX37_RS23470	COG0167	dihydroorotate dehydrogenase activity
CXX37_RS23470	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CXX37_RS23475	COG0493	'glutamate synthase
CXX37_RS23485	COG2949	membrane
CXX37_RS23495	COG1346	cytolysis
CXX37_RS23505	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CXX37_RS23520	COG1028	Short-chain dehydrogenase reductase Sdr
CXX37_RS23525	COG0586	Pfam SNARE associated Golgi protein
CXX37_RS23535	COG1686	Belongs to the peptidase S11 family
CXX37_RS23540	COG0277	FAD linked oxidase domain protein
CXX37_RS23545	COG1472	Belongs to the glycosyl hydrolase 3 family
CXX37_RS23550	COG1732	Glycine betaine
CXX37_RS23555	COG1174	glycine betaine transport
CXX37_RS23560	COG1125	glycine betaine transport
CXX37_RS23565	COG1174	glycine betaine transport
CXX37_RS23575	COG0789	Transcriptional regulator
CXX37_RS23580	COG3275	phosphorelay sensor kinase activity
CXX37_RS23585	COG3279	Response regulator of the LytR AlgR family
CXX37_RS23590	COG4807	Protein conserved in bacteria
CXX37_RS23595	COG4808	Protein conserved in bacteria
CXX37_RS23600	COG4715	Zinc finger, swim domain protein
CXX37_RS23605	COG3552	Protein containing von Willebrand factor type A (VWA) domain
CXX37_RS23610	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CXX37_RS23615	COG0714	Associated with various cellular activities
CXX37_RS23645	COG0489	protein tyrosine kinase activity
CXX37_RS23655	COG3539	Fimbrial protein
CXX37_RS23660	COG3121	Chaperone
CXX37_RS23665	COG3188	usher protein
CXX37_RS23670	COG3539	Fimbrial protein
CXX37_RS23675	COG5455	response to cobalt ion
CXX37_RS23695	COG0351	phosphomethylpyrimidine kinase
CXX37_RS23700	COG3757	hydrolase, family 25
CXX37_RS23705	COG2188	Transcriptional regulator
CXX37_RS23710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CXX37_RS23715	COG1397	ADP-ribosylglycohydrolase
CXX37_RS23720	COG2211	Major facilitator Superfamily
CXX37_RS23725	COG1830	Aldolase
CXX37_RS23740	COG1069	ribulokinase activity
CXX37_RS23765	COG1070	Carbohydrate kinase
CXX37_RS23775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CXX37_RS23790	COG4974	Belongs to the 'phage' integrase family
CXX37_RS23850	COG4695	Portal protein
CXX37_RS23990	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CXX37_RS24055	COG3436	PFAM IS66 Orf2 family protein
CXX37_RS24060	COG4372	Transposase
CXX37_RS24255	COG3328	transposase activity
CXX37_RS24275	COG1475	DNA binding
CXX37_RS24330	COG3328	transposase activity
CXX37_RS24360	COG3385	transposase activity
CXX37_RS24375	COG4584	PFAM Integrase catalytic
CXX37_RS24480	COG3436	PFAM IS66 Orf2 family protein
CXX37_RS24485	COG4372	Transposase
CXX37_RS24535	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
CXX37_RS24625	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
CXX37_RS24700	COG3436	PFAM IS66 Orf2 family protein
CXX37_RS24705	COG4372	Transposase
CXX37_RS24730	COG2026	Addiction module toxin, RelE StbE family
CXX37_RS24735	COG3077	Addiction module antitoxin, RelB DinJ family
CXX37_RS24740	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CXX37_RS24765	COG0582	viral genome integration into host DNA
CXX37_RS24795	COG4974	Belongs to the 'phage' integrase family
CXX37_RS24880	COG2948	multi-organism process
CXX37_RS24885	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
CXX37_RS24910	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CXX37_RS25005	COG0789	Transcriptional regulator
CXX37_RS25065	COG3436	PFAM IS66 Orf2 family protein
CXX37_RS25175	COG3385	transposase activity
CXX37_RS25245	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
CXX37_RS25250	COG2944	sequence-specific DNA binding
CXX37_RS25265	COG3385	transposase activity
CXX37_RS25275	COG2197	response regulator
CXX37_RS25285	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
CXX37_RS25350	COG0577	efflux transmembrane transporter activity
CXX37_RS25350	COG1136	(ABC) transporter
CXX37_RS25375	COG2801	Transposase and inactivated derivatives
CXX37_RS25395	COG3436	PFAM IS66 Orf2 family protein
CXX37_RS25410	COG4372	Transposase
CXX37_RS25415	COG3436	PFAM IS66 Orf2 family protein
CXX37_RS25430	COG3039	Transposase
CXX37_RS25590	COG3436	PFAM IS66 Orf2 family protein
CXX37_RS25595	COG4372	Transposase