locus-tag	class	description
C6W76_RS00005	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6W76_RS00005	COG1263	PTS System
C6W76_RS00010	COG1609	Transcriptional regulator
C6W76_RS00015	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6W76_RS00020	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
C6W76_RS00045	COG1349	DNA-binding transcription factor activity
C6W76_RS00050	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6W76_RS00055	COG1028	Short-chain dehydrogenase reductase Sdr
C6W76_RS00065	COG3732	PTS system glucitol sorbitol-specific
C6W76_RS00070	COG3730	PTS system glucitol sorbitol-specific
C6W76_RS00075	COG2951	lytic endotransglycosylase activity
C6W76_RS00080	COG1546	Belongs to the CinA family
C6W76_RS00095	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C6W76_RS00100	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
C6W76_RS00125	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C6W76_RS00130	COG1238	metal cluster binding
C6W76_RS00145	COG2814	Major facilitator Superfamily
C6W76_RS00150	COG1566	PFAM secretion protein HlyD family protein
C6W76_RS00155	COG1846	Transcriptional regulator
C6W76_RS00165	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
C6W76_RS00170	COG2814	Major facilitator Superfamily
C6W76_RS00180	COG2113	Glycine betaine
C6W76_RS00185	COG4176	ABC-type proline glycine betaine transport system permease component
C6W76_RS00190	COG4175	Glycine betaine
C6W76_RS00195	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C6W76_RS00200	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C6W76_RS00210	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C6W76_RS00215	COG4575	ribosome binding
C6W76_RS00230	COG2916	Histone family protein nucleoid-structuring protein H-NS
C6W76_RS00235	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C6W76_RS00240	COG0640	Transcriptional regulator
C6W76_RS00245	COG0401	homolog of Blt101
C6W76_RS00250	COG1652	LysM domain
C6W76_RS00255	COG1802	Transcriptional regulator
C6W76_RS00260	COG1113	amino acid transport
C6W76_RS00265	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C6W76_RS00270	COG1012	belongs to the aldehyde dehydrogenase family
C6W76_RS00275	COG0579	oxidoreductase
C6W76_RS00330	COG2867	negative regulation of translational initiation
C6W76_RS00340	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C6W76_RS00345	COG0497	DNA recombination
C6W76_RS00365	COG4536	flavin adenine dinucleotide binding
C6W76_RS00370	COG4137	Cytochrome C assembly protein
C6W76_RS00375	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C6W76_RS00400	COG2885	chlorophyll binding
C6W76_RS00420	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C6W76_RS00425	COG0287	Prephenate dehydrogenase
C6W76_RS00425	COG1605	Chorismate mutase
C6W76_RS00430	COG1605	Chorismate mutase
C6W76_RS00430	COG0077	Prephenate dehydratase
C6W76_RS00440	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C6W76_RS00450	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C6W76_RS00455	COG0564	pseudouridine synthase activity
C6W76_RS00465	COG0542	response to heat
C6W76_RS00495	COG0477	Major facilitator Superfamily
C6W76_RS00500	COG5544	Lipoprotein
C6W76_RS00505	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C6W76_RS00510	COG1042	CoA-binding domain protein
C6W76_RS00510	COG0045	succinate-CoA ligase (ADP-forming) activity
C6W76_RS00510	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C6W76_RS00515	COG3148	PFAM DTW domain containing protein
C6W76_RS00520	COG3118	belongs to the thioredoxin family
C6W76_RS00530	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C6W76_RS00550	COG0583	DNA-binding transcription factor activity
C6W76_RS00555	COG0513	Belongs to the DEAD box helicase family
C6W76_RS00565	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C6W76_RS00570	COG1595	DNA-templated transcription, initiation
C6W76_RS00575	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
C6W76_RS00580	COG3026	antisigma factor binding
C6W76_RS00585	COG3086	response to oxidative stress
C6W76_RS00595	COG0681	Belongs to the peptidase S26 family
C6W76_RS00645	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6W76_RS00650	COG1737	Transcriptional regulator
C6W76_RS00655	COG0560	Phosphoserine phosphatase
C6W76_RS00680	COG2205	protein histidine kinase activity
C6W76_RS00685	COG3170	Tfp pilus assembly protein FimV
C6W76_RS00690	COG2204	response regulator
C6W76_RS00695	COG0347	Belongs to the P(II) protein family
C6W76_RS00700	COG1017	nitric oxide dioxygenase activity
C6W76_RS00700	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C6W76_RS00710	COG1940	carbohydrate kinase activity
C6W76_RS00720	COG1879	ABC-type sugar transport system periplasmic component
C6W76_RS00730	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6W76_RS00735	COG1063	alcohol dehydrogenase
C6W76_RS00740	COG2017	converts alpha-aldose to the beta-anomer
C6W76_RS00745	COG2259	Doxx family
C6W76_RS00770	COG4638	Rieske (2fe-2S)
C6W76_RS00775	COG0583	DNA-binding transcription factor activity
C6W76_RS00780	COG2814	Major facilitator Superfamily
C6W76_RS00785	COG3711	transcriptional antiterminator
C6W76_RS00790	COG1073	alpha beta
C6W76_RS00795	COG0483	inositol monophosphate 1-phosphatase activity
C6W76_RS00815	COG0822	iron-sulfur transferase activity
C6W76_RS00835	COG0633	Ferredoxin
C6W76_RS00840	COG2975	iron-sulfur cluster assembly
C6W76_RS00855	COG2897	thiosulfate sulfurtransferase activity
C6W76_RS00860	COG2373	Large extracellular alpha-helical protein
C6W76_RS00865	COG4953	penicillin-binding protein 1C
C6W76_RS00900	COG2976	Protein conserved in bacteria
C6W76_RS00915	COG1645	bacterial-type flagellum-dependent swarming motility
C6W76_RS00925	COG0517	IMP dehydrogenase activity
C6W76_RS00925	COG0516	GMP reductase activity
C6W76_RS00965	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6W76_RS01075	COG3728	DNA packaging
C6W76_RS01075	COG5484	DNA packaging
C6W76_RS01215	COG3179	chitinase
C6W76_RS01230	COG3133	Outer membrane lipoprotein
C6W76_RS01255	COG2200	EAL domain
C6W76_RS01260	COG0248	Ppx GppA phosphatase
C6W76_RS01265	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
C6W76_RS01270	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C6W76_RS01290	COG2233	PERMEase
C6W76_RS01300	COG1393	Belongs to the ArsC family
C6W76_RS01305	COG4783	chaperone-mediated protein folding
C6W76_RS01310	COG0628	permease
C6W76_RS01315	COG2116	formate transmembrane transporter activity
C6W76_RS01320	COG3604	Transcriptional regulator
C6W76_RS01330	COG3260	NADH ubiquinone oxidoreductase 20
C6W76_RS01335	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C6W76_RS01340	COG3261	NADH dehydrogenase
C6W76_RS01340	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
C6W76_RS01345	COG0651	ATP synthesis coupled electron transport
C6W76_RS01350	COG4237	Hydrogenase 4 membrane
C6W76_RS01360	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C6W76_RS01365	COG0650	Formate hydrogenlyase subunit 4
C6W76_RS01375	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6W76_RS01380	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C6W76_RS01385	COG2716	regulation of RNA biosynthetic process
C6W76_RS01395	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
C6W76_RS01415	COG2321	neutral zinc metallopeptidase
C6W76_RS01425	COG0400	carboxylic ester hydrolase activity
C6W76_RS01440	COG1393	Belongs to the ArsC family
C6W76_RS01450	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C6W76_RS01455	COG3850	Histidine kinase
C6W76_RS01460	COG0493	'glutamate synthase
C6W76_RS01460	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6W76_RS01470	COG5342	invasion associated locus B
C6W76_RS01475	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C6W76_RS01480	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C6W76_RS01485	COG0280	phosphate acetyltransferase
C6W76_RS01485	COG0281	malic enzyme
C6W76_RS01495	COG4810	utilization protein
C6W76_RS01500	COG4917	ethanolamine utilization protein
C6W76_RS01505	COG4766	ethanolamine catabolic process
C6W76_RS01510	COG4812	Cobalamin adenosyltransferase
C6W76_RS01515	COG0280	phosphate acetyltransferase
C6W76_RS01520	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
C6W76_RS01525	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
C6W76_RS01530	COG1012	belongs to the aldehyde dehydrogenase family
C6W76_RS01535	COG4820	ethanolamine utilization protein (EutJ)
C6W76_RS01540	COG1454	alcohol dehydrogenase
C6W76_RS01545	COG3192	ethanolamine utilization protein
C6W76_RS01550	COG4819	ethanolamine utilization protein
C6W76_RS01555	COG4303	Ethanolamine ammonia lyase large subunit
C6W76_RS01565	COG4816	utilization protein
C6W76_RS01570	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
C6W76_RS01575	COG2207	Transcriptional regulator
C6W76_RS01585	COG0860	N-Acetylmuramoyl-L-alanine amidase
C6W76_RS01605	COG2837	iron assimilation
C6W76_RS01635	COG4150	thiosulfate binding
C6W76_RS01640	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
C6W76_RS01645	COG4208	sulfate ABC transporter
C6W76_RS01650	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C6W76_RS01655	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C6W76_RS01670	COG2190	(PTS) system
C6W76_RS01675	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C6W76_RS01680	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6W76_RS01685	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C6W76_RS01705	COG3530	Putative quorum-sensing-regulated virulence factor
C6W76_RS01710	COG0385	Bile acid
C6W76_RS01715	COG0583	DNA-binding transcription factor activity
C6W76_RS01750	COG3415	Transposase
C6W76_RS01755	COG3415	Transposase
C6W76_RS01770	COG2199	diguanylate cyclase activity
C6W76_RS01770	COG2200	EAL domain
C6W76_RS01775	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C6W76_RS01800	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6W76_RS01805	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6W76_RS01810	COG0006	proline dipeptidase activity
C6W76_RS01815	COG1363	Peptidase, m42
C6W76_RS01825	COG2207	Transcriptional regulator
C6W76_RS01830	COG3279	Response regulator of the LytR AlgR family
C6W76_RS01835	COG3275	phosphorelay sensor kinase activity
C6W76_RS01850	COG0436	Aminotransferase
C6W76_RS01860	COG1560	Kdo2-lipid A biosynthetic process
C6W76_RS01890	COG0028	Belongs to the TPP enzyme family
C6W76_RS01895	COG0679	Auxin Efflux Carrier
C6W76_RS01900	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C6W76_RS01905	COG0784	Response regulator, receiver
C6W76_RS01905	COG2198	Histidine kinase
C6W76_RS01905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6W76_RS01905	COG2205	protein histidine kinase activity
C6W76_RS01910	COG2197	response regulator
C6W76_RS01915	COG1566	PFAM secretion protein HlyD family protein
C6W76_RS01920	COG0477	Major facilitator Superfamily
C6W76_RS02000	COG3561	AntA/AntB antirepressor
C6W76_RS02240	COG3772	lysozyme
C6W76_RS02400	COG2116	formate transmembrane transporter activity
C6W76_RS02410	COG2853	Lipoprotein
C6W76_RS02425	COG2067	long-chain fatty acid transport protein
C6W76_RS02435	COG3691	Protein conserved in bacteria
C6W76_RS02450	COG2062	phosphohistidine phosphatase, SixA
C6W76_RS02455	COG3539	Fimbrial protein
C6W76_RS02465	COG3121	Chaperone
C6W76_RS02470	COG3539	Fimbrial protein
C6W76_RS02475	COG3539	Fimbrial protein
C6W76_RS02480	COG3539	Fimbrial protein
C6W76_RS02510	COG0730	response to heat
C6W76_RS02515	COG3101	peptidyl-lysine hydroxylation
C6W76_RS02530	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C6W76_RS02540	COG2814	Major facilitator Superfamily
C6W76_RS02555	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C6W76_RS02565	COG0586	Pfam SNARE associated Golgi protein
C6W76_RS02575	COG0285	dihydrofolate synthase activity
C6W76_RS02580	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
C6W76_RS02585	COG1286	toxin biosynthetic process
C6W76_RS02590	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C6W76_RS02595	COG0163	prenyltransferase activity
C6W76_RS02600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6W76_RS02605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6W76_RS02610	COG4215	(ABC) transporter
C6W76_RS02615	COG4160	amino acid transport
C6W76_RS02620	COG4598	ABC transporter
C6W76_RS02625	COG5464	transposase or invertase
C6W76_RS02630	COG1090	epimerase
C6W76_RS02635	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C6W76_RS02640	COG0625	glutathione transferase activity
C6W76_RS02645	COG0625	glutathione transferase activity
C6W76_RS02650	COG0622	Phosphoesterase
C6W76_RS02655	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
C6W76_RS02665	COG0857	belongs to the CobB CobQ family
C6W76_RS02665	COG0280	phosphate acetyltransferase
C6W76_RS02670	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C6W76_RS02685	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C6W76_RS02690	COG0471	metal ion transport
C6W76_RS02690	COG0490	domain, Protein
C6W76_RS02700	COG0436	Aminotransferase
C6W76_RS02710	COG0583	DNA-binding transcription factor activity
C6W76_RS02730	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
C6W76_RS02735	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
C6W76_RS02740	COG1034	ATP synthesis coupled electron transport
C6W76_RS02755	COG0839	Belongs to the complex I subunit 6 family
C6W76_RS02765	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C6W76_RS02770	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C6W76_RS02800	COG2153	protein acetylation
C6W76_RS02805	COG4575	ribosome binding
C6W76_RS02810	COG1169	isochorismate synthase
C6W76_RS02825	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C6W76_RS02835	COG0318	PFAM AMP-dependent synthetase and ligase
C6W76_RS02900	COG1414	Transcriptional regulator
C6W76_RS02910	COG2271	Major facilitator Superfamily
C6W76_RS02920	COG5464	transposase or invertase
C6W76_RS02925	COG0247	lactate metabolic process
C6W76_RS02935	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C6W76_RS02940	COG2271	Major facilitator Superfamily
C6W76_RS02945	COG0584	glycerophosphoryl diester phosphodiesterase
C6W76_RS02950	COG0583	DNA-binding transcription factor activity
C6W76_RS02955	COG3642	lipopolysaccharide core region biosynthetic process
C6W76_RS02960	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C6W76_RS02965	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C6W76_RS02970	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C6W76_RS02995	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C6W76_RS03000	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
C6W76_RS03005	COG3234	Protein of unknown function (DUF1175)
C6W76_RS03015	COG5445	Predicted secreted protein (DUF2300)
C6W76_RS03020	COG4676	Protein conserved in bacteria
C6W76_RS03025	COG0784	Response regulator, receiver
C6W76_RS03025	COG2205	protein histidine kinase activity
C6W76_RS03030	COG2197	response regulator
C6W76_RS03035	COG0642	Histidine kinase
C6W76_RS03035	COG2198	Histidine kinase
C6W76_RS03050	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C6W76_RS03055	COG1477	protein flavinylation
C6W76_RS03060	COG2169	Transcriptional regulator
C6W76_RS03060	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C6W76_RS03065	COG3145	DNA-N1-methyladenine dioxygenase activity
C6W76_RS03070	COG4615	Cyclic peptide transporter
C6W76_RS03090	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6W76_RS03090	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6W76_RS03095	COG3062	negative regulation of establishment of protein localization
C6W76_RS03105	COG0437	4 iron, 4 sulfur cluster binding
C6W76_RS03110	COG0348	domain, Protein
C6W76_RS03115	COG3043	anaerobic respiration
C6W76_RS03120	COG3005	denitrification pathway
C6W76_RS03125	COG4133	protoheme IX ABC transporter activity
C6W76_RS03130	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C6W76_RS03135	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C6W76_RS03140	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C6W76_RS03150	COG1138	Cytochrome C-type biogenesis protein
C6W76_RS03155	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C6W76_RS03160	COG3088	subunit of a heme lyase
C6W76_RS03160	COG4235	cytochrome complex assembly
C6W76_RS03165	COG2197	response regulator
C6W76_RS03205	COG3083	sulfuric ester hydrolase activity
C6W76_RS03225	COG1061	Type III restriction enzyme res subunit
C6W76_RS03235	COG1187	pseudouridine synthase activity
C6W76_RS03240	COG2814	Major facilitator Superfamily
C6W76_RS03255	COG4172	Belongs to the ABC transporter superfamily
C6W76_RS03260	COG4239	(ABC) transporter, permease
C6W76_RS03265	COG4174	ABC transporter (Permease)
C6W76_RS03270	COG4166	transmembrane transport
C6W76_RS03275	COG2200	EAL domain
C6W76_RS03280	COG0791	NLP P60 protein
C6W76_RS03285	COG0671	phosphoesterase, PA-phosphatase related
C6W76_RS03290	COG0523	cobalamin synthesis protein
C6W76_RS03295	COG0246	Mannitol dehydrogenase
C6W76_RS03310	COG2814	Major facilitator Superfamily
C6W76_RS03315	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6W76_RS03315	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6W76_RS03320	COG1105	Belongs to the carbohydrate kinase PfkB family
C6W76_RS03325	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6W76_RS03325	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6W76_RS03325	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
C6W76_RS03330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6W76_RS03335	COG2313	pseudouridylate synthase activity
C6W76_RS03340	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C6W76_RS03345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C6W76_RS03355	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C6W76_RS03360	COG1522	sequence-specific DNA binding
C6W76_RS03360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6W76_RS03370	COG2855	membrane
C6W76_RS03375	COG0583	DNA-binding transcription factor activity
C6W76_RS03385	COG0833	amino acid
C6W76_RS03395	COG4771	TonB-dependent receptor
C6W76_RS03405	COG0560	Phosphoserine phosphatase
C6W76_RS03420	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
C6W76_RS03440	COG2311	Membrane
C6W76_RS03450	COG1609	Transcriptional regulator
C6W76_RS03455	COG1879	ABC-type sugar transport system periplasmic component
C6W76_RS03460	COG1129	ABC transporter
C6W76_RS03465	COG4211	Belongs to the binding-protein-dependent transport system permease family
C6W76_RS03470	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
C6W76_RS03470	COG0167	dihydroorotate dehydrogenase activity
C6W76_RS03475	COG0493	'glutamate synthase
C6W76_RS03485	COG2949	membrane
C6W76_RS03495	COG1346	cytolysis
C6W76_RS03505	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C6W76_RS03530	COG1028	Short-chain dehydrogenase reductase Sdr
C6W76_RS03535	COG0586	Pfam SNARE associated Golgi protein
C6W76_RS03545	COG1686	Belongs to the peptidase S11 family
C6W76_RS03550	COG0277	FAD linked oxidase domain protein
C6W76_RS03555	COG1472	Belongs to the glycosyl hydrolase 3 family
C6W76_RS03560	COG1732	Glycine betaine
C6W76_RS03565	COG1174	glycine betaine transport
C6W76_RS03570	COG1125	glycine betaine transport
C6W76_RS03575	COG1174	glycine betaine transport
C6W76_RS03585	COG0789	Transcriptional regulator
C6W76_RS03680	COG4808	Protein conserved in bacteria
C6W76_RS03685	COG4807	Protein conserved in bacteria
C6W76_RS03690	COG3279	Response regulator of the LytR AlgR family
C6W76_RS03695	COG3275	phosphorelay sensor kinase activity
C6W76_RS03745	COG4715	Zinc finger, swim domain protein
C6W76_RS03750	COG3552	Protein containing von Willebrand factor type A (VWA) domain
C6W76_RS03755	COG2425	protein containing a von Willebrand factor type A (vWA) domain
C6W76_RS03760	COG0714	Associated with various cellular activities
C6W76_RS03775	COG3831	ATPase activity
C6W76_RS03785	COG0489	protein tyrosine kinase activity
C6W76_RS03805	COG3121	Chaperone
C6W76_RS03810	COG3188	usher protein
C6W76_RS03815	COG3539	Fimbrial protein
C6W76_RS03820	COG5455	response to cobalt ion
C6W76_RS03825	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
C6W76_RS03840	COG0351	phosphomethylpyrimidine kinase
C6W76_RS03845	COG3757	hydrolase, family 25
C6W76_RS03850	COG2188	Transcriptional regulator
C6W76_RS03855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6W76_RS03860	COG1397	ADP-ribosylglycohydrolase
C6W76_RS03865	COG2211	Major facilitator Superfamily
C6W76_RS03870	COG1830	Aldolase
C6W76_RS03885	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6W76_RS03890	COG3414	Phosphotransferase system galactitol-specific IIB component
C6W76_RS03895	COG3775	system Galactitol-specific IIC component
C6W76_RS03900	COG1063	alcohol dehydrogenase
C6W76_RS03925	COG0826	peptidase U32
C6W76_RS03935	COG3609	addiction module antidote protein, CC2985 family
C6W76_RS03945	COG0745	RESPONSE REGULATOR receiver
C6W76_RS03950	COG2205	protein histidine kinase activity
C6W76_RS03985	COG4245	von Willebrand factor, type A
C6W76_RS03990	COG0631	protein serine/threonine phosphatase activity
C6W76_RS03995	COG3779	Protein conserved in bacteria
C6W76_RS04000	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
C6W76_RS04005	COG0443	Heat shock 70 kDa protein
C6W76_RS04015	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C6W76_RS04020	COG5001	Diguanylate cyclase
C6W76_RS04020	COG5002	protein histidine kinase activity
C6W76_RS04020	COG3447	MASE1 domain protein
C6W76_RS04025	COG0572	uridine kinase
C6W76_RS04035	COG2982	Protein involved in outer membrane biogenesis
C6W76_RS04040	COG1253	flavin adenine dinucleotide binding
C6W76_RS04045	COG1596	polysaccharide export
C6W76_RS04050	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C6W76_RS04055	COG0489	protein tyrosine kinase activity
C6W76_RS04055	COG3206	protein involved in exopolysaccharide biosynthesis
C6W76_RS04060	COG0463	Glycosyl transferase, family 2
C6W76_RS04065	COG1045	serine acetyltransferase
C6W76_RS04070	COG0438	transferase activity, transferring glycosyl groups
C6W76_RS04080	COG1216	Glycosyl transferase, family 2
C6W76_RS04085	COG0110	maltose O-acetyltransferase activity
C6W76_RS04090	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
C6W76_RS04095	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C6W76_RS04100	COG1051	belongs to the nudix hydrolase family
C6W76_RS04105	COG0297	glycogen (starch) synthase activity
C6W76_RS04110	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
C6W76_RS04110	COG0662	Cupin 2, conserved barrel domain protein
C6W76_RS04115	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C6W76_RS04120	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C6W76_RS04125	COG2244	polysaccharide biosynthetic process
C6W76_RS04130	COG2327	Polysaccharide pyruvyl transferase
C6W76_RS04135	COG0438	transferase activity, transferring glycosyl groups
C6W76_RS04145	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C6W76_RS04170	COG1215	transferase activity, transferring glycosyl groups
C6W76_RS04170	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C6W76_RS04180	COG0438	transferase activity, transferring glycosyl groups
C6W76_RS04185	COG1086	Polysaccharide biosynthesis protein
C6W76_RS04195	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C6W76_RS04210	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C6W76_RS04215	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C6W76_RS04220	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
C6W76_RS04225	COG0140	phosphoribosyl-ATP diphosphatase activity
C6W76_RS04225	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C6W76_RS04240	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C6W76_RS04245	COG0131	Imidazoleglycerol-phosphate dehydratase
C6W76_RS04245	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C6W76_RS04255	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C6W76_RS04275	COG2161	toxin-antitoxin pair type II binding
C6W76_RS04285	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C6W76_RS04290	COG0583	DNA-binding transcription factor activity
C6W76_RS04300	COG0531	amino acid
C6W76_RS04305	COG2391	methyltransferase activity
C6W76_RS04310	COG0425	Belongs to the sulfur carrier protein TusA family
C6W76_RS04315	COG2925	Exonuclease
C6W76_RS04320	COG1686	Belongs to the peptidase S11 family
C6W76_RS04330	COG1289	transmembrane transporter activity
C6W76_RS04355	COG4656	Part of a membrane complex involved in electron transport
C6W76_RS04360	COG1454	alcohol dehydrogenase
C6W76_RS04360	COG1012	belongs to the aldehyde dehydrogenase family
C6W76_RS04375	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
C6W76_RS04390	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
C6W76_RS04450	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
C6W76_RS04465	COG1376	ErfK ybiS ycfS ynhG family protein
C6W76_RS04475	COG0583	DNA-binding transcription factor activity
C6W76_RS04480	COG0583	DNA-binding transcription factor activity
C6W76_RS04490	COG0534	Mate efflux family protein
C6W76_RS04510	COG0217	transcriptional regulatory protein
C6W76_RS04515	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C6W76_RS04520	COG0477	Major facilitator Superfamily
C6W76_RS04590	COG1403	HNH endonuclease
C6W76_RS04595	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C6W76_RS04655	COG3772	lysozyme
C6W76_RS04795	COG2032	superoxide dismutase activity
C6W76_RS04890	COG3038	cytochrome b561
C6W76_RS04910	COG3443	Belongs to the bacterial solute-binding protein 9 family
C6W76_RS04925	COG2351	hydroxyisourate hydrolase activity
C6W76_RS04930	COG0745	RESPONSE REGULATOR receiver
C6W76_RS04935	COG2205	protein histidine kinase activity
C6W76_RS04950	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C6W76_RS04960	COG1418	mRNA catabolic process
C6W76_RS04965	COG0270	DNA (cytosine-5-)-methyltransferase activity
C6W76_RS04970	COG3727	T/G mismatch-specific endonuclease activity
C6W76_RS04975	COG0697	spore germination
C6W76_RS04980	COG2354	Protein conserved in bacteria
C6W76_RS04985	COG5475	Uncharacterized small protein (DUF2158)
C6W76_RS04995	COG3706	GGDEF domain
C6W76_RS05015	COG2197	response regulator
C6W76_RS05020	COG1684	flagellar biosynthetic protein fliR
C6W76_RS05025	COG1987	bacterial-type flagellum assembly
C6W76_RS05030	COG1338	Plays a role in the flagellum-specific transport system
C6W76_RS05035	COG3190	flagellar
C6W76_RS05040	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C6W76_RS05045	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C6W76_RS05050	COG1580	Controls the rotational direction of flagella during chemotaxis
C6W76_RS05055	COG3144	bacterial-type flagellum assembly
C6W76_RS05060	COG2882	bacterial-type flagellum organization
C6W76_RS05065	COG1157	protein secretion by the type III secretion system
C6W76_RS05070	COG1317	bacterial-type flagellum organization
C6W76_RS05075	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C6W76_RS05080	COG1766	The M ring may be actively involved in energy transduction
C6W76_RS05095	COG2135	peptidase activity
C6W76_RS05100	COG0425	Belongs to the sulfur carrier protein TusA family
C6W76_RS05105	COG2391	methyltransferase activity
C6W76_RS05120	COG0366	Alpha amylase catalytic
C6W76_RS05130	COG1516	flagellar protein fliS
C6W76_RS05135	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C6W76_RS05140	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C6W76_RS05145	COG1191	sigma factor activity
C6W76_RS05155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6W76_RS05165	COG0765	amino acid transport
C6W76_RS05170	COG1126	abc transporter atp-binding protein
C6W76_RS05175	COG2197	response regulator
C6W76_RS05185	COG2197	response regulator
C6W76_RS05285	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C6W76_RS05290	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6W76_RS05385	COG4695	Portal protein
C6W76_RS05475	COG4974	Belongs to the 'phage' integrase family
C6W76_RS05480	COG3318	Belongs to the UPF0149 family
C6W76_RS05480	COG3012	SEC-C Motif Domain Protein
C6W76_RS05485	COG0814	amino acid
C6W76_RS05495	COG1528	Iron-storage protein
C6W76_RS05515	COG1528	Iron-storage protein
C6W76_RS05525	COG1879	ABC-type sugar transport system periplasmic component
C6W76_RS05530	COG1129	ABC transporter
C6W76_RS05535	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6W76_RS05540	COG1877	trehalose-phosphatase activity
C6W76_RS05550	COG0589	response to stress
C6W76_RS05565	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C6W76_RS05570	COG1360	Flagellar Motor Protein
C6W76_RS05575	COG2198	Histidine kinase
C6W76_RS05575	COG0643	Histidine kinase
C6W76_RS05585	COG0840	transmembrane signaling receptor activity
C6W76_RS05590	COG0840	transmembrane signaling receptor activity
C6W76_RS05595	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C6W76_RS05600	COG2201	protein-glutamate methylesterase activity
C6W76_RS05605	COG0745	RESPONSE REGULATOR receiver
C6W76_RS05610	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
C6W76_RS05615	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C6W76_RS05620	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C6W76_RS05630	COG3755	Protein conserved in bacteria
C6W76_RS05645	COG3102	Protein conserved in bacteria
C6W76_RS05655	COG3005	denitrification pathway
C6W76_RS05660	COG0243	molybdopterin cofactor binding
C6W76_RS05675	COG3788	relative of glutathione S-transferase, MAPEG superfamily
C6W76_RS05680	COG1801	Protein of unknown function DUF72
C6W76_RS05685	COG0582	viral genome integration into host DNA
C6W76_RS05750	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C6W76_RS05790	COG1484	DNA-dependent DNA replication
C6W76_RS05795	COG0305	Participates in initiation and elongation during chromosome replication
C6W76_RS05805	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C6W76_RS05865	COG3772	lysozyme
C6W76_RS05875	COG4220	transposase activity
C6W76_RS05980	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6W76_RS06015	COG0727	PFAM Uncharacterised protein family (UPF0153)
C6W76_RS06025	COG1335	isochorismatase
C6W76_RS06035	COG0494	nUDIX hydrolase
C6W76_RS06040	COG0217	transcriptional regulatory protein
C6W76_RS06070	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C6W76_RS06080	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
C6W76_RS06085	COG0739	heme binding
C6W76_RS06090	COG1560	Kdo2-lipid A biosynthetic process
C6W76_RS06095	COG0469	pyruvate kinase activity
C6W76_RS06100	COG1737	Transcriptional regulator
C6W76_RS06105	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C6W76_RS06110	COG0129	dihydroxy-acid dehydratase activity
C6W76_RS06115	COG0800	Aldolase
C6W76_RS06125	COG3141	response to X-ray
C6W76_RS06135	COG2979	Protein of unknown function (DUF533)
C6W76_RS06140	COG1770	oligopeptidase
C6W76_RS06145	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6W76_RS06150	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C6W76_RS06160	COG2372	response to copper ion
C6W76_RS06165	COG1276	copper resistance
C6W76_RS06175	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C6W76_RS06195	COG3008	intermembrane lipid transfer
C6W76_RS06200	COG2995	paraquat-inducible protein a
C6W76_RS06205	COG1956	GAF domain-containing protein
C6W76_RS06215	COG0793	Belongs to the peptidase S41A family
C6W76_RS06230	COG1414	Transcriptional regulator
C6W76_RS06265	COG2226	methyltransferase
C6W76_RS06285	COG3716	PTS system mannose fructose sorbose family IID component
C6W76_RS06290	COG3715	PTS system
C6W76_RS06295	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6W76_RS06295	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6W76_RS06310	COG1253	flavin adenine dinucleotide binding
C6W76_RS06315	COG2200	EAL domain
C6W76_RS06320	COG1760	l-serine dehydratase
C6W76_RS06330	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C6W76_RS06345	COG0251	oxidation-reduction process
C6W76_RS06350	COG1199	ATP-dependent helicase activity
C6W76_RS06355	COG1214	PFAM Peptidase M22, glycoprotease
C6W76_RS06360	COG3065	identical protein binding
C6W76_RS06365	COG0318	PFAM AMP-dependent synthetase and ligase
C6W76_RS06370	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
C6W76_RS06375	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C6W76_RS06380	COG4638	Rieske (2fe-2S)
C6W76_RS06385	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C6W76_RS06390	COG0473	3-isopropylmalate dehydrogenase activity
C6W76_RS06405	COG3615	Tellurite resistance protein tehB
C6W76_RS06415	COG2261	transglycosylase associated protein
C6W76_RS06430	COG2199	diguanylate cyclase activity
C6W76_RS06430	COG2203	Gaf domain
C6W76_RS06435	COG3042	response to heat
C6W76_RS06440	COG3189	MarR family transcriptional regulator
C6W76_RS06445	COG2807	transmembrane transport
C6W76_RS06450	COG2207	Transcriptional regulator
C6W76_RS06465	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C6W76_RS06470	COG2199	diguanylate cyclase activity
C6W76_RS06475	COG2199	diguanylate cyclase activity
C6W76_RS06485	COG2766	serine protein kinase
C6W76_RS06490	COG3713	MltA-interacting MipA family protein
C6W76_RS06495	COG0656	L-ascorbic acid biosynthetic process
C6W76_RS06500	COG0676	glucose-6-phosphate 1-epimerase activity
C6W76_RS06505	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C6W76_RS06515	COG3139	Protein of unknown function (DUF1315)
C6W76_RS06520	COG1063	alcohol dehydrogenase
C6W76_RS06540	COG1349	DNA-binding transcription factor activity
C6W76_RS06545	COG2814	Major facilitator Superfamily
C6W76_RS06550	COG1335	isochorismatase
C6W76_RS06555	COG0252	asparaginase activity
C6W76_RS06560	COG0616	signal peptide processing
C6W76_RS06570	COG0778	Nitroreductase
C6W76_RS06580	COG0709	Synthesizes selenophosphate from selenide and ATP
C6W76_RS06585	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C6W76_RS06595	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C6W76_RS06605	COG0494	nUDIX hydrolase
C6W76_RS06610	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C6W76_RS06615	COG2897	thiosulfate sulfurtransferase activity
C6W76_RS06620	COG4136	ATPase activity
C6W76_RS06625	COG4135	transport system, permease component
C6W76_RS06630	COG4134	Bacterial extracellular solute-binding protein
C6W76_RS06635	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C6W76_RS06640	COG0398	Pfam SNARE associated Golgi protein
C6W76_RS06650	COG0398	Pfam SNARE associated Golgi protein
C6W76_RS06655	COG0708	Exodeoxyribonuclease III
C6W76_RS06685	COG3678	ATP-independent chaperone mediated protein folding
C6W76_RS06695	COG0322	excinuclease ABC activity
C6W76_RS06705	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C6W76_RS06715	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C6W76_RS06720	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C6W76_RS06725	COG1447	Phosphotransferase system cellobiose-specific component IIA
C6W76_RS06730	COG2169	Transcriptional regulator
C6W76_RS06730	COG1917	Cupin 2, conserved barrel domain protein
C6W76_RS06735	COG1486	melibiose metabolic process
C6W76_RS06745	COG0753	catalase activity
C6W76_RS06760	COG1823	symporter activity
C6W76_RS06765	COG1988	membrane-bound metal-dependent
C6W76_RS06770	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C6W76_RS06780	COG3001	Fructosamine kinase
C6W76_RS06790	COG1105	Belongs to the carbohydrate kinase PfkB family
C6W76_RS06795	COG3137	Salt-induced outer membrane protein
C6W76_RS06850	COG0386	Belongs to the glutathione peroxidase family
C6W76_RS06860	COG0791	NLP P60 protein
C6W76_RS06865	COG2200	EAL domain
C6W76_RS06875	COG4256	Hemin uptake protein
C6W76_RS06880	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C6W76_RS06895	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C6W76_RS06895	COG0574	Belongs to the PEP-utilizing enzyme family
C6W76_RS06905	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C6W76_RS06915	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C6W76_RS06920	COG2086	electron transfer activity
C6W76_RS06930	COG2207	Transcriptional regulator
C6W76_RS06930	COG1917	Cupin 2, conserved barrel domain protein
C6W76_RS06935	COG1960	acyl-CoA dehydrogenase activity
C6W76_RS06940	COG4670	ketone body catabolic process
C6W76_RS06960	COG0738	Major facilitator superfamily
C6W76_RS06975	COG0628	permease
C6W76_RS06980	COG0247	lactate metabolic process
C6W76_RS06980	COG0277	FAD linked oxidase domain protein
C6W76_RS06985	COG2050	protein possibly involved in aromatic compounds catabolism
C6W76_RS06995	COG0316	Belongs to the HesB IscA family
C6W76_RS07000	COG0719	Fe-S assembly protein
C6W76_RS07005	COG0396	ATPase activity
C6W76_RS07010	COG0719	Fe-S assembly protein
C6W76_RS07030	COG4238	major outer membrane lipoprotein
C6W76_RS07035	COG0469	pyruvate kinase activity
C6W76_RS07045	COG0437	4 iron, 4 sulfur cluster binding
C6W76_RS07060	COG0437	4 iron, 4 sulfur cluster binding
C6W76_RS07065	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
C6W76_RS07075	COG4529	Protein conserved in bacteria
C6W76_RS07095	COG3468	outer membrane autotransporter barrel domain protein
C6W76_RS07105	COG0307	riboflavin synthase, alpha
C6W76_RS07110	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C6W76_RS07115	COG2814	Major facilitator Superfamily
C6W76_RS07120	COG0583	DNA-binding transcription factor activity
C6W76_RS07140	COG2814	Major facilitator Superfamily
C6W76_RS07145	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C6W76_RS07150	COG0791	NLP P60 protein
C6W76_RS07155	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C6W76_RS07170	COG0346	lactoylglutathione lyase activity
C6W76_RS07175	COG1902	pentaerythritol trinitrate reductase activity
C6W76_RS07180	COG1309	transcriptional regulator
C6W76_RS07185	COG3313	Fe-S protein
C6W76_RS07205	COG2032	superoxide dismutase activity
C6W76_RS07215	COG1566	PFAM secretion protein HlyD family protein
C6W76_RS07230	COG3133	Outer membrane lipoprotein
C6W76_RS07240	COG3895	Periplasmic Protein
C6W76_RS07255	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
C6W76_RS07260	COG0625	glutathione transferase activity
C6W76_RS07265	COG3104	oligopeptide transport
C6W76_RS07275	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C6W76_RS07285	COG4659	FMN binding
C6W76_RS07330	COG0673	inositol 2-dehydrogenase activity
C6W76_RS07340	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C6W76_RS07345	COG1263	PTS System
C6W76_RS07345	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6W76_RS07350	COG1609	Transcriptional regulator
C6W76_RS07360	COG1309	transcriptional regulator
C6W76_RS07365	COG3250	beta-galactosidase activity
C6W76_RS07380	COG5339	Protein conserved in bacteria
C6W76_RS07385	COG1482	cell wall glycoprotein biosynthetic process
C6W76_RS07390	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C6W76_RS07390	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C6W76_RS07395	COG0114	fumarate hydratase activity
C6W76_RS07405	COG2205	protein histidine kinase activity
C6W76_RS07410	COG0745	RESPONSE REGULATOR receiver
C6W76_RS07415	COG3136	membrane protein required for alginate biosynthesis
C6W76_RS07425	COG0531	amino acid
C6W76_RS07440	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
C6W76_RS07445	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
C6W76_RS07450	COG0628	permease
C6W76_RS07470	COG3591	Belongs to the peptidase S1B family
C6W76_RS07490	COG2814	Major facilitator Superfamily
C6W76_RS07495	COG0583	DNA-binding transcription factor activity
C6W76_RS07500	COG1940	carbohydrate kinase activity
C6W76_RS07505	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C6W76_RS07515	COG3381	protein complex oligomerization
C6W76_RS07520	COG3302	dmso reductase anchor subunit
C6W76_RS07525	COG0437	4 iron, 4 sulfur cluster binding
C6W76_RS07530	COG0582	viral genome integration into host DNA
C6W76_RS07550	COG2207	Transcriptional regulator
C6W76_RS07595	COG3772	lysozyme
C6W76_RS07620	COG1403	HNH endonuclease
C6W76_RS07625	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C6W76_RS07645	COG2207	Transcriptional regulator
C6W76_RS07715	COG3111	PFAM Bacterial OB fold (BOF) protein
C6W76_RS07720	COG3706	GGDEF domain
C6W76_RS07730	COG2814	Major facilitator Superfamily
C6W76_RS07735	COG0697	spore germination
C6W76_RS07745	COG4977	sequence-specific DNA binding
C6W76_RS07750	COG1846	Transcriptional regulator
C6W76_RS07770	COG0583	DNA-binding transcription factor activity
C6W76_RS07775	COG1012	belongs to the aldehyde dehydrogenase family
C6W76_RS07790	COG3781	membrane
C6W76_RS07845	COG1396	sequence-specific DNA binding
C6W76_RS07850	COG3550	peptidyl-serine autophosphorylation
C6W76_RS07865	COG3188	usher protein
C6W76_RS07870	COG3539	Fimbrial protein
C6W76_RS07875	COG3539	Fimbrial protein
C6W76_RS07885	COG3539	Fimbrial protein
C6W76_RS07890	COG0243	molybdopterin cofactor binding
C6W76_RS07905	COG3119	arylsulfatase activity
C6W76_RS07910	COG0641	radical SAM
C6W76_RS07915	COG4178	(ABC) transporter
C6W76_RS07920	COG4771	TonB-dependent receptor
C6W76_RS07925	COG0612	Peptidase, M16
C6W76_RS07930	COG0076	glutamate decarboxylase activity
C6W76_RS07935	COG0531	amino acid
C6W76_RS07940	COG1649	PFAM Uncharacterised BCR, COG1649
C6W76_RS07960	COG0747	negative chemotaxis
C6W76_RS07965	COG0601	transmembrane transport
C6W76_RS07970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C6W76_RS07975	COG0444	Belongs to the ABC transporter superfamily
C6W76_RS07980	COG4608	Belongs to the ABC transporter superfamily
C6W76_RS07985	COG1764	response to oxidative stress
C6W76_RS08015	COG3093	addiction module antidote protein HigA
C6W76_RS08020	COG2864	formate dehydrogenase
C6W76_RS08025	COG0437	4 iron, 4 sulfur cluster binding
C6W76_RS08035	COG0697	spore germination
C6W76_RS08040	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C6W76_RS08050	COG4886	Leucine-rich repeat (LRR) protein
C6W76_RS08060	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C6W76_RS08065	COG1140	nitrate reductase beta subunit
C6W76_RS08070	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C6W76_RS08075	COG2181	nitrate reductase activity
C6W76_RS08080	COG0384	phenazine biosynthesis protein PhzF
C6W76_RS08090	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C6W76_RS08100	COG5433	transposase activity
C6W76_RS08115	COG3209	COG3209 Rhs family protein
C6W76_RS08150	COG0625	glutathione transferase activity
C6W76_RS08155	COG1113	amino acid transport
C6W76_RS08160	COG3391	amine dehydrogenase activity
C6W76_RS08170	COG4772	TonB-dependent receptor
C6W76_RS08175	COG1802	Transcriptional regulator
C6W76_RS08180	COG2130	NADP-dependent
C6W76_RS08190	COG1247	-acetyltransferase
C6W76_RS08195	COG3238	Protein conserved in bacteria
C6W76_RS08230	COG1177	transmembrane transport
C6W76_RS08235	COG1176	ABC-type spermidine putrescine transport system, permease component I
C6W76_RS08240	COG3842	ATPase activity
C6W76_RS08245	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C6W76_RS08250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C6W76_RS08255	COG1598	PFAM Uncharacterised protein family UPF0150
C6W76_RS08260	COG1724	mRNA binding
C6W76_RS08275	COG1396	sequence-specific DNA binding
C6W76_RS08280	COG3135	benzoate transporter
C6W76_RS08285	COG0675	Transposase, IS605 OrfB family
C6W76_RS08300	COG0500	methyltransferase
C6W76_RS08310	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C6W76_RS08320	COG2841	Protein conserved in bacteria
C6W76_RS08350	COG0583	DNA-binding transcription factor activity
C6W76_RS08355	COG0840	transmembrane signaling receptor activity
C6W76_RS08370	COG3038	cytochrome b561
C6W76_RS08375	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C6W76_RS08385	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C6W76_RS08390	COG1643	Atp-dependent helicase
C6W76_RS08400	COG0671	phosphoesterase, PA-phosphatase related
C6W76_RS08400	COG2453	phosphatase
C6W76_RS08405	COG2267	carboxylic ester hydrolase activity
C6W76_RS08410	COG4589	Belongs to the CDS family
C6W76_RS08415	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C6W76_RS08425	COG0667	Aldo Keto reductase
C6W76_RS08430	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C6W76_RS08435	COG3327	negative regulation of DNA-templated transcription, initiation
C6W76_RS08440	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
C6W76_RS08445	COG0183	Belongs to the thiolase family
C6W76_RS08450	COG2050	protein possibly involved in aromatic compounds catabolism
C6W76_RS08455	COG1250	3-hydroxyacyl-CoA dehydrogenase
C6W76_RS08460	COG1024	Enoyl-CoA hydratase
C6W76_RS08465	COG1024	Enoyl-CoA hydratase
C6W76_RS08470	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C6W76_RS08475	COG2151	metal-sulfur cluster biosynthetic enzyme
C6W76_RS08480	COG3396	Phenylacetate-CoA oxygenase
C6W76_RS08485	COG3460	Phenylacetate-CoA oxygenase
C6W76_RS08490	COG3396	Phenylacetate-CoA oxygenase
C6W76_RS08495	COG1012	belongs to the aldehyde dehydrogenase family
C6W76_RS08495	COG2030	dehydratase
C6W76_RS08500	COG3733	amine oxidase
C6W76_RS08505	COG1012	belongs to the aldehyde dehydrogenase family
C6W76_RS08510	COG2207	Transcriptional regulator
C6W76_RS08515	COG3784	Protein of unknown function (DUF1318)
C6W76_RS08525	COG2911	Protein conserved in bacteria
C6W76_RS08530	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C6W76_RS08535	COG3187	Heat shock protein
C6W76_RS08540	COG3042	response to heat
C6W76_RS08545	COG0674	pyruvate-flavodoxin oxidoreductase activity
C6W76_RS08545	COG1013	pyruvate-flavodoxin oxidoreductase activity
C6W76_RS08545	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C6W76_RS08545	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
C6W76_RS08555	COG0589	response to stress
C6W76_RS08565	COG0513	Belongs to the DEAD box helicase family
C6W76_RS08580	COG3706	GGDEF domain
C6W76_RS08585	COG2840	Smr protein MutS2
C6W76_RS08595	COG2207	Transcriptional regulator
C6W76_RS08605	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
C6W76_RS08610	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C6W76_RS08615	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C6W76_RS08620	COG0589	response to stress
C6W76_RS08625	COG3182	Iron-regulated membrane protein
C6W76_RS08630	COG0668	transmembrane transport
C6W76_RS08635	COG4166	transmembrane transport
C6W76_RS08640	COG0583	DNA-binding transcription factor activity
C6W76_RS08645	COG1073	alpha beta
C6W76_RS08650	COG1073	alpha beta
C6W76_RS08655	COG0702	epimerase
C6W76_RS08660	COG2866	Carboxypeptidase
C6W76_RS08665	COG4948	Mandelate Racemase Muconate Lactonizing
C6W76_RS08670	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
C6W76_RS08710	COG3283	Transcriptional regulator of aromatic amino acids metabolism
C6W76_RS08720	COG3106	COG3106 Predicted ATPase
C6W76_RS08725	COG1609	Transcriptional regulator
C6W76_RS08735	COG3842	ATPase activity
C6W76_RS08740	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C6W76_RS08750	COG0673	inositol 2-dehydrogenase activity
C6W76_RS08755	COG1082	Xylose isomerase domain protein TIM barrel
C6W76_RS08760	COG1063	alcohol dehydrogenase
C6W76_RS08765	COG0395	ABC-type sugar transport system, permease component
C6W76_RS08770	COG1175	transmembrane transport
C6W76_RS08775	COG1653	transport
C6W76_RS08780	COG0366	Alpha amylase catalytic
C6W76_RS08785	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C6W76_RS08795	COG1983	PspC domain protein
C6W76_RS08805	COG1842	Phage shock protein A
C6W76_RS08810	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C6W76_RS08815	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C6W76_RS08820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C6W76_RS08825	COG1012	belongs to the aldehyde dehydrogenase family
C6W76_RS08830	COG1396	sequence-specific DNA binding
C6W76_RS08830	COG1917	Cupin 2, conserved barrel domain protein
C6W76_RS08835	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C6W76_RS08840	COG0174	glutamine synthetase
C6W76_RS08845	COG0531	amino acid
C6W76_RS08860	COG4166	transmembrane transport
C6W76_RS08865	COG4168	peptide transport system, permease
C6W76_RS08890	COG1546	Belongs to the CinA family
C6W76_RS08895	COG0339	signal peptide processing
C6W76_RS08905	COG4221	oxidoreductase activity
C6W76_RS08910	COG1802	Transcriptional regulator
C6W76_RS08920	COG0246	Mannitol dehydrogenase
C6W76_RS08925	COG0477	Major facilitator Superfamily
C6W76_RS08960	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6W76_RS09045	COG1030	water channel activity
C6W76_RS09065	COG4220	transposase activity
C6W76_RS09090	COG3772	lysozyme
C6W76_RS09130	COG2207	Transcriptional regulator
C6W76_RS09145	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C6W76_RS09150	COG1403	HNH endonuclease
C6W76_RS09195	COG1846	Transcriptional regulator
C6W76_RS09210	COG1396	sequence-specific DNA binding
C6W76_RS09295	COG3772	lysozyme
C6W76_RS09420	COG3646	Phage regulatory protein
C6W76_RS09500	COG3093	addiction module antidote protein HigA
C6W76_RS09560	COG4171	peptide transport system, permease
C6W76_RS09565	COG4172	Belongs to the ABC transporter superfamily
C6W76_RS09570	COG4172	Belongs to the ABC transporter superfamily
C6W76_RS09575	COG2852	Protein conserved in bacteria
C6W76_RS09580	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C6W76_RS09585	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C6W76_RS09585	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C6W76_RS09600	COG5001	Diguanylate cyclase
C6W76_RS09610	COG1349	DNA-binding transcription factor activity
C6W76_RS09620	COG0023	Translation Initiation Factor
C6W76_RS09630	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
C6W76_RS09635	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
C6W76_RS09640	COG0671	phosphoesterase, PA-phosphatase related
C6W76_RS09650	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C6W76_RS09670	COG0583	DNA-binding transcription factor activity
C6W76_RS09680	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C6W76_RS09695	COG0616	signal peptide processing
C6W76_RS09700	COG1028	Short-chain dehydrogenase reductase Sdr
C6W76_RS09705	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
C6W76_RS09710	COG1187	pseudouridine synthase activity
C6W76_RS09715	COG0009	L-threonylcarbamoyladenylate synthase
C6W76_RS09720	COG0613	PHP domain protein
C6W76_RS09730	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C6W76_RS09735	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C6W76_RS09735	COG0512	Glutamine amidotransferase of anthranilate synthase
C6W76_RS09740	COG0135	phosphoribosylanthranilate isomerase activity
C6W76_RS09740	COG0134	indole-3-glycerol-phosphate synthase activity
C6W76_RS09755	COG3729	General stress protein
C6W76_RS09765	COG3685	Protein conserved in bacteria
C6W76_RS09840	COG0582	viral genome integration into host DNA
C6W76_RS09975	COG3047	cAMP biosynthetic process
C6W76_RS09995	COG1607	acyl-coa hydrolase
C6W76_RS10000	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
C6W76_RS10025	COG2350	Protein conserved in bacteria
C6W76_RS10030	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C6W76_RS10050	COG4608	Belongs to the ABC transporter superfamily
C6W76_RS10055	COG0444	Belongs to the ABC transporter superfamily
C6W76_RS10060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C6W76_RS10065	COG0601	transmembrane transport
C6W76_RS10070	COG4166	transmembrane transport
C6W76_RS10080	COG2095	MarC family integral membrane protein
C6W76_RS10085	COG1012	belongs to the aldehyde dehydrogenase family
C6W76_RS10085	COG1454	alcohol dehydrogenase
C6W76_RS10090	COG1435	thymidine kinase activity
C6W76_RS10100	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C6W76_RS10105	COG0745	RESPONSE REGULATOR receiver
C6W76_RS10110	COG1752	Esterase of the alpha-beta hydrolase superfamily
C6W76_RS10120	COG0788	formyltetrahydrofolate deformylase activity
C6W76_RS10135	COG2181	nitrate reductase activity
C6W76_RS10140	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C6W76_RS10145	COG1140	nitrate reductase beta subunit
C6W76_RS10150	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C6W76_RS10155	COG2223	nitrite transmembrane transporter activity
C6W76_RS10165	COG3850	Histidine kinase
C6W76_RS10170	COG2197	response regulator
C6W76_RS10175	COG4932	domain protein
C6W76_RS10180	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
C6W76_RS10185	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
C6W76_RS10190	COG4572	Cation transport regulator
C6W76_RS10195	COG0387	Pfam Sodium calcium exchanger
C6W76_RS10220	COG2912	Transglutaminase-like superfamily
C6W76_RS10225	COG3094	Invasion gene expression up-regulator, SirB
C6W76_RS10230	COG2890	protein-(glutamine-N5) methyltransferase activity
C6W76_RS10260	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C6W76_RS10270	COG0659	secondary active sulfate transmembrane transporter activity
C6W76_RS10285	COG0012	GTP binding
C6W76_RS10295	COG3468	outer membrane autotransporter barrel domain protein
C6W76_RS10300	COG3284	Transcriptional regulator
C6W76_RS10305	COG2376	Dihydroxyacetone kinase
C6W76_RS10310	COG1461	Dihydroxyacetone kinase
C6W76_RS10315	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
C6W76_RS10315	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6W76_RS10315	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C6W76_RS10340	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
C6W76_RS10355	COG1619	proteins homologs of microcin C7 resistance protein MccF
C6W76_RS10370	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C6W76_RS10380	COG2719	SpoVR family
C6W76_RS10395	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C6W76_RS10400	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C6W76_RS10405	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C6W76_RS10420	COG0179	Fumarylacetoacetate (FAA) hydrolase
C6W76_RS10450	COG2894	cell division
C6W76_RS10495	COG0538	isocitrate dehydrogenase activity
C6W76_RS10500	COG0456	acetyltransferase
C6W76_RS10510	COG4571	Outer membrane protease
C6W76_RS10525	COG0500	methyltransferase
C6W76_RS10535	COG3729	General stress protein
C6W76_RS10540	COG3685	Protein conserved in bacteria
C6W76_RS10545	COG3685	Protein conserved in bacteria
C6W76_RS10550	COG3546	catalase activity
C6W76_RS10675	COG0582	viral genome integration into host DNA
C6W76_RS10680	COG0538	isocitrate dehydrogenase activity
C6W76_RS10685	COG1187	pseudouridine synthase activity
C6W76_RS10705	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C6W76_RS10715	COG2205	protein histidine kinase activity
C6W76_RS10720	COG2850	peptidyl-arginine hydroxylation
C6W76_RS10775	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6W76_RS10865	COG0740	serine-type endopeptidase activity
C6W76_RS10910	COG3772	lysozyme
C6W76_RS10960	COG0484	heat shock protein binding
C6W76_RS10965	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C6W76_RS10980	COG3111	PFAM Bacterial OB fold (BOF) protein
C6W76_RS11010	COG1846	Transcriptional regulator
C6W76_RS11015	COG1484	DNA-dependent DNA replication
C6W76_RS11030	COG4197	protein conserved in bacteria, prophage-related
C6W76_RS11055	COG1177	transmembrane transport
C6W76_RS11060	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C6W76_RS11065	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C6W76_RS11075	COG4591	ABC-type transport system involved in lipoprotein release permease component
C6W76_RS11085	COG4591	ABC-type transport system involved in lipoprotein release permease component
C6W76_RS11095	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C6W76_RS11100	COG1376	ErfK ybiS ycfS ynhG family protein
C6W76_RS11100	COG1388	LysM domain
C6W76_RS11110	COG1309	transcriptional regulator
C6W76_RS11115	COG3134	Outer membrane lipoprotein
C6W76_RS11125	COG1252	NADH dehydrogenase
C6W76_RS11145	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
C6W76_RS11150	COG5633	Lipoprotein
C6W76_RS11155	COG0537	adenosine 5'-monophosphoramidase activity
C6W76_RS11165	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6W76_RS11165	COG1263	PTS System
C6W76_RS11170	COG0084	hydrolase, TatD family'
C6W76_RS11175	COG0470	DNA polymerase III
C6W76_RS11185	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C6W76_RS11190	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C6W76_RS11195	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C6W76_RS11205	COG1028	Short-chain dehydrogenase reductase Sdr
C6W76_RS11210	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C6W76_RS11230	COG1399	metal-binding, possibly nucleic acid-binding protein
C6W76_RS11235	COG0424	maF-like protein
C6W76_RS11240	COG0564	pseudouridine synthase activity
C6W76_RS11250	COG1530	ribonuclease E activity
C6W76_RS11255	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C6W76_RS11260	COG1256	bacterial-type flagellum assembly
C6W76_RS11265	COG3951	Flagellar rod assembly protein muramidase FlgJ
C6W76_RS11265	COG1705	Flagellar rod assembly protein muramidase FlgJ
C6W76_RS11280	COG4786	Flagellar basal body rod
C6W76_RS11290	COG1749	Flagellar hook protein flgE
C6W76_RS11295	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C6W76_RS11300	COG1558	bacterial-type flagellum-dependent cell motility
C6W76_RS11305	COG1815	bacterial-type flagellum-dependent cell motility
C6W76_RS11310	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
C6W76_RS11315	COG2747	anti-sigma28 factor FlgM
C6W76_RS11320	COG3418	PFAM FlgN family protein
C6W76_RS11325	COG0728	peptidoglycan biosynthetic process
C6W76_RS11330	COG0673	inositol 2-dehydrogenase activity
C6W76_RS11340	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C6W76_RS11350	COG2999	glutathione oxidoreductase activity
C6W76_RS11390	COG3038	cytochrome b561
C6W76_RS11395	COG2353	YceI-like domain
C6W76_RS11405	COG1560	Kdo2-lipid A biosynthetic process
C6W76_RS11480	COG5645	(Lipo)protein
C6W76_RS11485	COG2943	transferase activity, transferring hexosyl groups
C6W76_RS11510	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C6W76_RS11515	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C6W76_RS11550	COG2197	response regulator
C6W76_RS11565	COG1462	curli production assembly transport component CsgG
C6W76_RS11575	COG3381	protein complex oligomerization
C6W76_RS11620	COG1649	PFAM Uncharacterised BCR, COG1649
C6W76_RS11620	COG0726	polysaccharide deacetylase
C6W76_RS11625	COG1215	transferase activity, transferring glycosyl groups
C6W76_RS11630	COG3658	cytochrome
C6W76_RS11635	COG1702	phosphate starvation-inducible protein PhoH
C6W76_RS11645	COG2822	iron ion transport
C6W76_RS11665	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C6W76_RS11670	COG0506	proline dehydrogenase activity
C6W76_RS11670	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C6W76_RS11670	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C6W76_RS11675	COG1309	transcriptional regulator
C6W76_RS11685	COG1335	isochorismatase
C6W76_RS11710	COG2233	PERMEase
C6W76_RS11715	COG3729	General stress protein
C6W76_RS11760	COG0243	molybdopterin cofactor binding
C6W76_RS11765	COG3005	denitrification pathway
C6W76_RS11770	COG0745	RESPONSE REGULATOR receiver
C6W76_RS11775	COG1879	ABC-type sugar transport system periplasmic component
C6W76_RS11780	COG2198	Histidine kinase
C6W76_RS11780	COG2205	protein histidine kinase activity
C6W76_RS11780	COG0784	Response regulator, receiver
C6W76_RS11805	COG1278	Cold shock
C6W76_RS11810	COG1278	Cold shock
C6W76_RS11830	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C6W76_RS11835	COG1596	polysaccharide export
C6W76_RS11840	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C6W76_RS11845	COG0489	protein tyrosine kinase activity
C6W76_RS11845	COG3206	protein involved in exopolysaccharide biosynthesis
C6W76_RS11860	COG1294	oxidase, subunit
C6W76_RS11865	COG1271	oxidase subunit
C6W76_RS11870	COG1773	rubredoxin
C6W76_RS11875	COG1999	signal sequence binding
C6W76_RS11880	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C6W76_RS11885	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
C6W76_RS11890	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
C6W76_RS11895	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
C6W76_RS11920	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6W76_RS11955	COG1196	nuclear chromosome segregation
C6W76_RS12025	COG4220	transposase activity
C6W76_RS12060	COG3772	lysozyme
C6W76_RS12105	COG0484	heat shock protein binding
C6W76_RS12110	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C6W76_RS12115	COG1403	HNH endonuclease
C6W76_RS12260	COG0670	Belongs to the BI1 family
C6W76_RS12265	COG2920	part of a sulfur-relay system
C6W76_RS12270	COG1254	Belongs to the acylphosphatase family
C6W76_RS12285	COG1832	CoA-binding protein
C6W76_RS12300	COG0210	DNA helicase
C6W76_RS12305	COG3304	Inner membrane component domain
C6W76_RS12310	COG1289	transmembrane transporter activity
C6W76_RS12315	COG3070	regulator of competence-specific genes
C6W76_RS12330	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
C6W76_RS12330	COG2885	chlorophyll binding
C6W76_RS12340	COG1067	ATP-dependent peptidase activity
C6W76_RS12350	COG3130	regulation of translation
C6W76_RS12355	COG3009	Protein conserved in bacteria
C6W76_RS12360	COG3008	intermembrane lipid transfer
C6W76_RS12360	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C6W76_RS12365	COG2995	paraquat-inducible protein a
C6W76_RS12370	COG0488	(ABC) transporter
C6W76_RS12380	COG0633	Ferredoxin
C6W76_RS12380	COG3217	Mosc domain protein beta barrel domain protein
C6W76_RS12395	COG3121	Chaperone
C6W76_RS12400	COG3539	Fimbrial protein
C6W76_RS12405	COG3539	Fimbrial protein
C6W76_RS12420	COG3121	Chaperone
C6W76_RS12425	COG3539	Fimbrial protein
C6W76_RS12435	COG0431	NADPH-dependent FMN reductase
C6W76_RS12440	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C6W76_RS12450	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C6W76_RS12460	COG0308	aminopeptidase N
C6W76_RS12485	COG1448	Aminotransferase
C6W76_RS12490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C6W76_RS12495	COG3108	Peptidase M15
C6W76_RS12505	COG2989	Protein conserved in bacteria
C6W76_RS12515	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
C6W76_RS12525	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C6W76_RS12530	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C6W76_RS12535	COG3173	Aminoglycoside phosphotransferase
C6W76_RS12550	COG3214	Protein conserved in bacteria
C6W76_RS12560	COG1132	(ABC) transporter
C6W76_RS12585	COG2842	Transposition protein
C6W76_RS12615	COG4396	Host-nuclease inhibitor protein Gam
C6W76_RS12665	COG5566	PFAM Mor transcription activator
C6W76_RS12700	COG4373	Mu-like prophage FluMu protein gp28
C6W76_RS12705	COG4383	Mu-like prophage protein gp29
C6W76_RS12710	COG2369	cell adhesion
C6W76_RS12715	COG5005	Phage virion morphogenesis
C6W76_RS12720	COG4388	Caudovirus prohead serine protease
C6W76_RS12725	COG4397	Mu-like prophage major head subunit gpT
C6W76_RS12750	COG4386	tail sheath protein
C6W76_RS12760	COG4518	Phage tail assembly chaperone proteins, E, or 41 or 14
C6W76_RS12780	COG4384	Bacteriophage Mu Gp45 protein
C6W76_RS12790	COG3299	homolog of phage Mu protein gp47
C6W76_RS12800	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6W76_RS12820	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C6W76_RS12850	COG0270	DNA (cytosine-5-)-methyltransferase activity
C6W76_RS12865	COG0539	negative regulation of cytoplasmic translation
C6W76_RS12875	COG0501	Belongs to the peptidase M48B family
C6W76_RS12890	COG2323	membrane
C6W76_RS12895	COG1944	ATP diphosphatase activity
C6W76_RS12900	COG2116	formate transmembrane transporter activity
C6W76_RS12905	COG1882	Formate acetyltransferase
C6W76_RS13055	COG4695	Portal protein
C6W76_RS13130	COG4974	Belongs to the 'phage' integrase family
C6W76_RS13135	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C6W76_RS13140	COG2249	NAD(P)H dehydrogenase (quinone) activity
C6W76_RS13145	COG0583	DNA-binding transcription factor activity
C6W76_RS13160	COG1335	isochorismatase
C6W76_RS13165	COG3302	dmso reductase anchor subunit
C6W76_RS13170	COG0437	4 iron, 4 sulfur cluster binding
C6W76_RS13175	COG0243	molybdopterin cofactor binding
C6W76_RS13185	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C6W76_RS13200	COG1522	sequence-specific DNA binding
C6W76_RS13210	COG0492	ferredoxin-NADP+ reductase activity
C6W76_RS13215	COG4988	ABC transporter
C6W76_RS13220	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C6W76_RS13240	COG0542	response to heat
C6W76_RS13375	COG1278	Cold shock
C6W76_RS13380	COG0577	efflux transmembrane transporter activity
C6W76_RS13380	COG1136	(ABC) transporter
C6W76_RS13385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6W76_RS13390	COG2990	Protein conserved in bacteria
C6W76_RS13395	COG3593	DNA synthesis involved in DNA repair
C6W76_RS13410	COG2431	L-lysine efflux transmembrane transporter activity
C6W76_RS13420	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C6W76_RS13425	COG0028	Belongs to the TPP enzyme family
C6W76_RS13430	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
C6W76_RS13435	COG0702	epimerase
C6W76_RS13440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C6W76_RS13445	COG3023	N-Acetylmuramoyl-L-alanine amidase
C6W76_RS13460	COG1126	abc transporter atp-binding protein
C6W76_RS13465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6W76_RS13470	COG4215	(ABC) transporter
C6W76_RS13475	COG4160	amino acid transport
C6W76_RS13480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6W76_RS13495	COG1177	transmembrane transport
C6W76_RS13500	COG1176	ABC-type spermidine putrescine transport system, permease component I
C6W76_RS13505	COG3842	ATPase activity
C6W76_RS13510	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C6W76_RS13530	COG0778	Nitroreductase
C6W76_RS13540	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C6W76_RS13555	COG3226	Transcriptional regulator
C6W76_RS13560	COG0738	Major facilitator superfamily
C6W76_RS13565	COG0561	phosphatase activity
C6W76_RS13575	COG2814	Major facilitator Superfamily
C6W76_RS13580	COG0671	phosphoesterase, PA-phosphatase related
C6W76_RS13585	COG1349	DNA-binding transcription factor activity
C6W76_RS13590	COG1686	Belongs to the peptidase S11 family
C6W76_RS13595	COG0625	glutathione transferase activity
C6W76_RS13600	COG2133	pyrroloquinoline quinone binding
C6W76_RS13615	COG2199	diguanylate cyclase activity
C6W76_RS13620	COG2200	EAL domain
C6W76_RS13645	COG1446	asparaginase
C6W76_RS13650	COG0303	'Molybdopterin
C6W76_RS13655	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C6W76_RS13660	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C6W76_RS13670	COG1882	Formate acetyltransferase
C6W76_RS13675	COG0561	phosphatase activity
C6W76_RS13685	COG0488	(ABC) transporter
C6W76_RS13690	COG1376	ErfK ybiS ycfS ynhG family protein
C6W76_RS13695	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C6W76_RS13700	COG1321	iron dependent repressor
C6W76_RS13710	COG2194	sulfuric ester hydrolase activity
C6W76_RS13715	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
C6W76_RS13720	COG5006	permease, DMT superfamily
C6W76_RS13745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6W76_RS13750	COG0765	amino acid transport
C6W76_RS13755	COG1126	abc transporter atp-binding protein
C6W76_RS13760	COG0668	transmembrane transport
C6W76_RS13785	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C6W76_RS13795	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
C6W76_RS13800	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C6W76_RS13805	COG1199	ATP-dependent helicase activity
C6W76_RS13815	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
C6W76_RS13820	COG0513	Belongs to the DEAD box helicase family
C6W76_RS13825	COG1309	transcriptional regulator
C6W76_RS13835	COG1131	(ABC) transporter
C6W76_RS13840	COG0842	Transport permease protein
C6W76_RS13845	COG0842	Transport permease protein
C6W76_RS13855	COG3568	Endonuclease Exonuclease Phosphatase
C6W76_RS13860	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C6W76_RS13865	COG0392	lysyltransferase activity
C6W76_RS13870	COG0670	Belongs to the BI1 family
C6W76_RS13875	COG0670	Belongs to the BI1 family
C6W76_RS13880	COG0314	molybdopterin synthase activity
C6W76_RS13885	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C6W76_RS13895	COG0521	Mo-molybdopterin cofactor biosynthetic process
C6W76_RS13905	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C6W76_RS13915	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C6W76_RS13920	COG2226	methyltransferase
C6W76_RS13935	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C6W76_RS13940	COG1881	PFAM PEBP family protein
C6W76_RS14040	COG0582	viral genome integration into host DNA
C6W76_RS14045	COG4677	pectinesterase activity
C6W76_RS14050	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C6W76_RS14060	COG2828	Protein conserved in bacteria
C6W76_RS14065	COG0583	DNA-binding transcription factor activity
C6W76_RS14075	COG0561	phosphatase activity
C6W76_RS14080	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
C6W76_RS14085	COG4149	molybdate abc transporter
C6W76_RS14090	COG0725	ABC transporter, periplasmic molybdate-binding protein
C6W76_RS14105	COG3585	molybdate ion transport
C6W76_RS14105	COG2005	Transcriptional regulator
C6W76_RS14110	COG1119	ATPase activity
C6W76_RS14115	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C6W76_RS14120	COG1085	galactose-1-phosphate uridylyltransferase
C6W76_RS14130	COG2017	converts alpha-aldose to the beta-anomer
C6W76_RS14140	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C6W76_RS14155	COG1230	cation diffusion facilitator family transporter
C6W76_RS14160	COG3201	nicotinamide mononucleotide transporter
C6W76_RS14195	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
C6W76_RS14200	COG2885	chlorophyll binding
C6W76_RS14210	COG3064	Membrane
C6W76_RS14215	COG0848	biopolymer transport protein
C6W76_RS14220	COG0811	peptide transport
C6W76_RS14225	COG0824	Thioesterase
C6W76_RS14230	COG3790	cyd operon protein YbgE
C6W76_RS14235	COG4890	Cyd operon protein YbgT
C6W76_RS14240	COG1294	oxidase, subunit
C6W76_RS14245	COG1271	oxidase subunit
C6W76_RS14250	COG0383	alpha-mannosidase activity
C6W76_RS14260	COG2188	Transcriptional regulator
C6W76_RS14265	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C6W76_RS14275	COG0508	dehydrogenase complex catalyzes the overall conversion of
C6W76_RS14280	COG0567	Dehydrogenase, E1 component
C6W76_RS14285	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C6W76_RS14290	COG1053	succinate dehydrogenase
C6W76_RS14295	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
C6W76_RS14300	COG2009	succinate dehydrogenase
C6W76_RS14315	COG0372	Belongs to the citrate synthase family
C6W76_RS14320	COG3539	Fimbrial protein
C6W76_RS14325	COG3188	usher protein
C6W76_RS14330	COG3121	Chaperone
C6W76_RS14335	COG3539	Fimbrial protein
C6W76_RS14340	COG3180	Ammonia monooxygenase
C6W76_RS14355	COG1984	allophanate hydrolase subunit 2
C6W76_RS14360	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C6W76_RS14365	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C6W76_RS14375	COG0415	Belongs to the DNA photolyase family
C6W76_RS14380	COG3272	Protein of unknown function (DUF1722)
C6W76_RS14390	COG5433	transposase activity
C6W76_RS14405	COG3209	COG3209 Rhs family protein
C6W76_RS14405	COG3209	COG3209 Rhs family protein
C6W76_RS14435	COG2205	protein histidine kinase activity
C6W76_RS14440	COG0745	RESPONSE REGULATOR receiver
C6W76_RS14455	COG1982	Orn Lys Arg decarboxylase major
C6W76_RS14460	COG0531	amino acid
C6W76_RS14465	COG0033	Phosphoglucomutase
C6W76_RS14470	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
C6W76_RS14475	COG0596	Alpha beta hydrolase
C6W76_RS14485	COG0716	FMN binding
C6W76_RS14495	COG0735	belongs to the Fur family
C6W76_RS14520	COG2190	(PTS) system
C6W76_RS14520	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6W76_RS14520	COG1263	PTS System
C6W76_RS14530	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C6W76_RS14535	COG1846	Transcriptional regulator
C6W76_RS14535	COG1940	carbohydrate kinase activity
C6W76_RS14540	COG0647	UMP catabolic process
C6W76_RS14545	COG0367	asparagine synthase
C6W76_RS14590	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C6W76_RS14600	COG1702	phosphate starvation-inducible protein PhoH
C6W76_RS14610	COG4535	Mg2 and Co2 transporter CorC
C6W76_RS14615	COG0815	Transfers the fatty acyl group on membrane lipoproteins
C6W76_RS14630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6W76_RS14635	COG0765	amino acid transport
C6W76_RS14640	COG0765	amino acid transport
C6W76_RS14645	COG1126	abc transporter atp-binding protein
C6W76_RS14655	COG0443	Heat shock 70 kDa protein
C6W76_RS14660	COG2214	Heat shock protein DnaJ domain protein
C6W76_RS14665	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C6W76_RS14670	COG2214	Heat shock protein DnaJ domain protein
C6W76_RS14675	COG2214	Heat shock protein DnaJ domain protein
C6W76_RS14685	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C6W76_RS14690	COG2888	peptidyl-tyrosine sulfation
C6W76_RS14705	COG1466	dna polymerase III delta subunit
C6W76_RS14715	COG0406	alpha-ribazole phosphatase activity
C6W76_RS14720	COG0799	negative regulation of ribosome biogenesis
C6W76_RS14730	COG0768	penicillin binding
C6W76_RS14735	COG0772	Belongs to the SEDS family
C6W76_RS14740	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C6W76_RS14745	COG1686	Belongs to the peptidase S11 family
C6W76_RS14765	COG0583	DNA-binding transcription factor activity
C6W76_RS14780	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C6W76_RS14785	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C6W76_RS14815	COG3069	C4-dicarboxylate transmembrane transporter activity
C6W76_RS14820	COG4565	transcriptional regulatory protein
C6W76_RS14825	COG3290	protein histidine kinase activity
C6W76_RS14830	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
C6W76_RS14840	COG2301	Belongs to the HpcH HpaI aldolase family
C6W76_RS14845	COG3051	citrate lyase alpha subunit
C6W76_RS14865	COG3719	Belongs to the RNase T2 family
C6W76_RS14875	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C6W76_RS14885	COG1063	alcohol dehydrogenase
C6W76_RS14890	COG0589	response to stress
C6W76_RS14895	COG3634	alkyl hydroperoxide reductase activity
C6W76_RS14900	COG0450	alkyl hydroperoxide reductase
C6W76_RS14905	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C6W76_RS14910	COG0583	DNA-binding transcription factor activity
C6W76_RS14915	COG3969	phosphoadenosine phosphosulfate
C6W76_RS14925	COG0436	Aminotransferase
C6W76_RS14930	COG0371	Dehydrogenase
C6W76_RS14935	COG2879	small protein
C6W76_RS14940	COG1966	Carbon starvation protein
C6W76_RS14945	COG2050	protein possibly involved in aromatic compounds catabolism
C6W76_RS14950	COG1028	Short-chain dehydrogenase reductase Sdr
C6W76_RS14955	COG3433	isochorismatase activity
C6W76_RS14955	COG1535	isochorismatase
C6W76_RS14960	COG1021	2,3-dihydroxybenzoate-AMP ligase
C6W76_RS14965	COG1169	isochorismate synthase
C6W76_RS14975	COG4592	Periplasmic binding protein
C6W76_RS14985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6W76_RS14990	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6W76_RS14995	COG1120	ATPase activity
C6W76_RS15000	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
C6W76_RS15005	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
C6W76_RS15005	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C6W76_RS15010	COG3251	PFAM MbtH domain protein
C6W76_RS15015	COG2382	esterase
C6W76_RS15020	COG4771	TonB-dependent receptor
C6W76_RS15030	COG2977	Belongs to the P-Pant transferase superfamily
C6W76_RS15060	COG2315	Protein conserved in bacteria
C6W76_RS15065	COG0778	Nitroreductase
C6W76_RS15070	COG0668	transmembrane transport
C6W76_RS15075	COG1113	amino acid transport
C6W76_RS15080	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C6W76_RS15085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6W76_RS15090	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6W76_RS15095	COG1538	Outer membrane efflux protein
C6W76_RS15105	COG0745	RESPONSE REGULATOR receiver
C6W76_RS15110	COG5002	protein histidine kinase activity
C6W76_RS15150	COG5433	transposase activity
C6W76_RS15155	COG1215	transferase activity, transferring glycosyl groups
C6W76_RS15160	COG4783	chaperone-mediated protein folding
C6W76_RS15175	COG2207	Transcriptional regulator
C6W76_RS15190	COG4571	Outer membrane protease
C6W76_RS15205	COG0500	methyltransferase
C6W76_RS15270	COG0484	heat shock protein binding
C6W76_RS15440	COG2197	response regulator
C6W76_RS15455	COG3188	usher protein
C6W76_RS15460	COG3121	Chaperone
C6W76_RS15465	COG3539	Fimbrial protein
C6W76_RS15475	COG2501	S4 domain
C6W76_RS15480	COG1988	membrane-bound metal-dependent
C6W76_RS15490	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C6W76_RS15505	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C6W76_RS15510	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C6W76_RS15515	COG0549	Belongs to the carbamate kinase family
C6W76_RS15525	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C6W76_RS15530	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C6W76_RS15535	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
C6W76_RS15540	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C6W76_RS15545	COG3257	ureidoglycine aminohydrolase activity
C6W76_RS15550	COG1929	Belongs to the glycerate kinase type-1 family
C6W76_RS15555	COG2233	PERMEase
C6W76_RS15565	COG1953	Uracil, thiamine, allantoin
C6W76_RS15570	COG2084	Dehydrogenase
C6W76_RS15575	COG3622	Belongs to the hyi family
C6W76_RS15580	COG3960	tartronate-semialdehyde synthase activity
C6W76_RS15585	COG1414	Transcriptional regulator
C6W76_RS15595	COG0583	DNA-binding transcription factor activity
C6W76_RS15615	COG3209	COG3209 Rhs family protein
C6W76_RS15620	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
C6W76_RS15625	COG4181	ATPase activity
C6W76_RS15630	COG2755	lipolytic protein G-D-S-L family
C6W76_RS15635	COG0300	oxidoreductase activity
C6W76_RS15640	COG3118	belongs to the thioredoxin family
C6W76_RS15645	COG0390	transport system, permease component
C6W76_RS15650	COG4619	ABC transporter
C6W76_RS15655	COG0330	HflC and HflK could
C6W76_RS15660	COG1585	Membrane protein implicated in regulation of membrane protease activity
C6W76_RS15665	COG0789	Transcriptional regulator
C6W76_RS15670	COG0531	amino acid
C6W76_RS15680	COG2217	Heavy metal translocating P-type atpase
C6W76_RS15685	COG3093	addiction module antidote protein HigA
C6W76_RS15695	COG3735	TraB family
C6W76_RS15705	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C6W76_RS15710	COG0737	Belongs to the 5'-nucleotidase family
C6W76_RS15725	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C6W76_RS15725	COG4651	solute:proton antiporter activity
C6W76_RS15730	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6W76_RS15770	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C6W76_RS15785	COG2832	Protein of unknown function (DUF454)
C6W76_RS15790	COG3923	Primosomal replication protein n
C6W76_RS15800	COG3264	Mechanosensitive ion channel
C6W76_RS15800	COG1196	nuclear chromosome segregation
C6W76_RS15810	COG1309	transcriptional regulator
C6W76_RS15815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6W76_RS15820	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C6W76_RS15835	COG0110	maltose O-acetyltransferase activity
C6W76_RS15845	COG4943	cyclic-guanylate-specific phosphodiesterase activity
C6W76_RS15850	COG5507	3-demethylubiquinone-9 3-methyltransferase
C6W76_RS15860	COG3695	enzyme binding
C6W76_RS15865	COG3126	Type III secretion system lipoprotein chaperone (YscW)
C6W76_RS15870	COG1946	Acyl-CoA thioesterase
C6W76_RS15875	COG0004	ammonium transporteR
C6W76_RS15880	COG0347	Belongs to the P(II) protein family
C6W76_RS15885	COG1132	(ABC) transporter
C6W76_RS15890	COG1132	(ABC) transporter
C6W76_RS15895	COG1522	sequence-specific DNA binding
C6W76_RS15905	COG4533	DNA binding
C6W76_RS15915	COG0824	Thioesterase
C6W76_RS15920	COG1555	photosystem II stabilization
C6W76_RS15925	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C6W76_RS15930	COG0776	regulation of translation
C6W76_RS15935	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C6W76_RS15960	COG0271	Belongs to the BolA IbaG family
C6W76_RS15965	COG3056	Lipoprotein
C6W76_RS15970	COG2223	nitrite transmembrane transporter activity
C6W76_RS15975	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C6W76_RS15980	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C6W76_RS15985	COG1845	cytochrome c oxidase, subunit III
C6W76_RS15990	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C6W76_RS16015	COG2814	Major facilitator Superfamily
C6W76_RS16025	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C6W76_RS16030	COG0693	protein deglycase activity
C6W76_RS16045	COG0142	geranyltranstransferase activity
C6W76_RS16055	COG0667	Aldo Keto reductase
C6W76_RS16060	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C6W76_RS16065	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C6W76_RS16080	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C6W76_RS16080	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C6W76_RS16090	COG4238	major outer membrane lipoprotein
C6W76_RS16095	COG3248	Nucleoside-binding outer membrane protein
C6W76_RS16100	COG1403	HNH endonuclease
C6W76_RS16105	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C6W76_RS16110	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C6W76_RS16115	COG1862	Preprotein translocase
C6W76_RS16135	COG0366	Alpha amylase catalytic
C6W76_RS16140	COG1113	amino acid transport
C6W76_RS16145	COG1114	Component of the transport system for branched-chain amino acids
C6W76_RS16150	COG5002	protein histidine kinase activity
C6W76_RS16155	COG0745	RESPONSE REGULATOR receiver
C6W76_RS16160	COG0420	3'-5' exonuclease activity
C6W76_RS16165	COG0419	ATPase involved in DNA repair
C6W76_RS16170	COG2814	Major facilitator Superfamily
C6W76_RS16200	COG4126	flavin adenine dinucleotide binding
C6W76_RS16225	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C6W76_RS16230	COG3706	GGDEF domain
C6W76_RS16255	COG1181	Belongs to the D-alanine--D-alanine ligase family
C6W76_RS16280	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
C6W76_RS16290	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C6W76_RS16295	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C6W76_RS16310	COG3468	outer membrane autotransporter barrel domain protein
C6W76_RS16320	COG0113	porphobilinogen synthase activity
C6W76_RS16325	COG2175	clavaminate synthase activity
C6W76_RS16330	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C6W76_RS16340	COG4521	taurine ABC transporter
C6W76_RS16350	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C6W76_RS16355	COG1215	transferase activity, transferring glycosyl groups
C6W76_RS16390	COG3122	Protein conserved in bacteria
C6W76_RS16395	COG2814	Major facilitator Superfamily
C6W76_RS16430	COG1414	Transcriptional regulator
C6W76_RS16435	COG1609	Transcriptional regulator
C6W76_RS16450	COG2223	nitrite transmembrane transporter activity
C6W76_RS16455	COG0110	maltose O-acetyltransferase activity
C6W76_RS16460	COG2807	transmembrane transport
C6W76_RS16470	COG0288	reversible hydration of carbon dioxide
C6W76_RS16475	COG0583	DNA-binding transcription factor activity
C6W76_RS16480	COG0402	S-adenosylhomocysteine deaminase activity
C6W76_RS16485	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C6W76_RS16490	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C6W76_RS16495	COG2079	MmgE PrpD family protein
C6W76_RS16500	COG0372	Belongs to the citrate synthase family
C6W76_RS16505	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C6W76_RS16510	COG3829	transcription factor binding
C6W76_RS16520	COG1280	lysine exporter protein (LysE YggA)
C6W76_RS16540	COG1064	alcohol dehydrogenase
C6W76_RS16550	COG0549	Belongs to the carbamate kinase family
C6W76_RS16560	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C6W76_RS16570	COG0666	response to abiotic stimulus
C6W76_RS16585	COG0583	DNA-binding transcription factor activity
C6W76_RS16590	COG2200	EAL domain
C6W76_RS16590	COG2771	luxR family
C6W76_RS16600	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C6W76_RS16640	COG1556	Lactate utilization protein
C6W76_RS16645	COG1139	Iron-sulfur cluster binding protein
C6W76_RS16650	COG0247	lactate metabolic process
C6W76_RS16655	COG2207	Transcriptional regulator
C6W76_RS16660	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C6W76_RS16670	COG3059	membrane
C6W76_RS16675	COG0656	L-ascorbic acid biosynthetic process
C6W76_RS16680	COG3708	Transcriptional regulator
C6W76_RS16680	COG2207	Transcriptional regulator
C6W76_RS16785	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C6W76_RS16805	COG2195	Cleaves the N-terminal amino acid of tripeptides
C6W76_RS16810	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
C6W76_RS16840	COG0454	-acetyltransferase
C6W76_RS16870	COG0791	NLP P60 protein
C6W76_RS16875	COG3077	Addiction module antitoxin, RelB DinJ family
C6W76_RS16880	COG3041	Addiction module toxin RelE StbE family
C6W76_RS16885	COG3034	peptidoglycan biosynthetic process
C6W76_RS16890	COG0121	glutamine amidotransferase
C6W76_RS16900	COG1960	acyl-CoA dehydrogenase activity
C6W76_RS16910	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C6W76_RS16925	COG3209	COG3209 Rhs family protein
C6W76_RS16925	COG3209	COG3209 Rhs family protein
C6W76_RS16940	COG5433	transposase activity
C6W76_RS16975	COG3157	Type VI secretion system effector, Hcp
C6W76_RS16980	COG4104	PAAR repeat-containing protein
C6W76_RS17005	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6W76_RS17015	COG2226	methyltransferase
C6W76_RS17025	COG1388	LysM domain
C6W76_RS17025	COG0741	lytic transglycosylase activity
C6W76_RS17030	COG2226	methyltransferase
C6W76_RS17040	COG0583	DNA-binding transcription factor activity
C6W76_RS17045	COG0656	L-ascorbic acid biosynthetic process
C6W76_RS17080	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C6W76_RS17085	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C6W76_RS17090	COG2011	ABC-type metal ion transport system permease component
C6W76_RS17095	COG1464	Belongs to the NlpA lipoprotein family
C6W76_RS17105	COG1720	tRNA m6t6A37 methyltransferase activity
C6W76_RS17120	COG3015	lipoprotein NlpE involved in copper resistance
C6W76_RS17125	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
C6W76_RS17130	COG4681	YaeQ
C6W76_RS17140	COG4568	rho-dependent transcription termination
C6W76_RS17150	COG0346	lactoylglutathione lyase activity
C6W76_RS17155	COG1982	Orn Lys Arg decarboxylase major
C6W76_RS17165	COG0587	DNA-directed DNA polymerase activity
C6W76_RS17190	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C6W76_RS17195	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
C6W76_RS17205	COG0750	zinc metalloprotease
C6W76_RS17210	COG0575	Belongs to the CDS family
C6W76_RS17215	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C6W76_RS17220	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C6W76_RS17255	COG0024	Methionine aminopeptidase
C6W76_RS17275	COG3835	regulator
C6W76_RS17280	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C6W76_RS17300	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C6W76_RS17305	COG2860	membrane
C6W76_RS17325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6W76_RS17330	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C6W76_RS17335	COG1120	ATPase activity
C6W76_RS17340	COG4774	siderophore transport
C6W76_RS17345	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C6W76_RS17355	COG1643	Atp-dependent helicase
C6W76_RS17360	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C6W76_RS17370	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C6W76_RS17380	COG0617	tRNA 3'-terminal CCA addition
C6W76_RS17385	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C6W76_RS17390	COG3539	Fimbrial protein
C6W76_RS17395	COG3121	Chaperone
C6W76_RS17400	COG3188	usher protein
C6W76_RS17410	COG3539	Fimbrial protein
C6W76_RS17425	COG3539	Fimbrial protein
C6W76_RS17430	COG3539	Fimbrial protein
C6W76_RS17445	COG5464	transposase or invertase
C6W76_RS17465	COG0726	polysaccharide deacetylase
C6W76_RS17470	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6W76_RS17475	COG0842	Transport permease protein
C6W76_RS17480	COG1131	(ABC) transporter
C6W76_RS17485	COG0288	reversible hydration of carbon dioxide
C6W76_RS17490	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
C6W76_RS17495	COG4993	Dehydrogenase
C6W76_RS17500	COG2132	Multicopper oxidase
C6W76_RS17525	COG1049	propionate catabolic process, 2-methylcitrate cycle
C6W76_RS17540	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C6W76_RS17545	COG0508	dehydrogenase complex catalyzes the overall conversion of
C6W76_RS17550	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
C6W76_RS17560	COG2186	Transcriptional regulator
C6W76_RS17565	COG1113	amino acid transport
C6W76_RS17570	COG3725	Membrane protein required for beta-lactamase induction
C6W76_RS17575	COG3023	N-Acetylmuramoyl-L-alanine amidase
C6W76_RS17580	COG0157	Belongs to the NadC ModD family
C6W76_RS17590	COG4969	Belongs to the N-Me-Phe pilin family
C6W76_RS17595	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C6W76_RS17600	COG1459	type II secretion system
C6W76_RS17610	COG0237	dephospho-CoA kinase activity
C6W76_RS17625	COG0494	nUDIX hydrolase
C6W76_RS17645	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C6W76_RS17650	COG0849	cell division
C6W76_RS17660	COG1181	Belongs to the D-alanine--D-alanine ligase family
C6W76_RS17675	COG0772	Belongs to the SEDS family
C6W76_RS17690	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C6W76_RS17695	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C6W76_RS17700	COG0768	penicillin binding
C6W76_RS17705	COG3116	cell division
C6W76_RS17725	COG1609	Transcriptional regulator
C6W76_RS17735	COG0440	acetolactate synthase activity
C6W76_RS17740	COG0028	Belongs to the TPP enzyme family
C6W76_RS17745	COG0583	DNA-binding transcription factor activity
C6W76_RS17775	COG2814	Major facilitator Superfamily
C6W76_RS17790	COG4143	(ABC) transporter
C6W76_RS17795	COG1178	ABC-type Fe3 transport system permease component
C6W76_RS17805	COG0586	Pfam SNARE associated Golgi protein
C6W76_RS17810	COG4977	sequence-specific DNA binding
C6W76_RS17830	COG0235	Class ii aldolase
C6W76_RS17835	COG0417	DNA replication proofreading
C6W76_RS17845	COG0564	pseudouridine synthase activity
C6W76_RS17850	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
C6W76_RS17860	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C6W76_RS17885	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C6W76_RS17900	COG2271	Major facilitator Superfamily
C6W76_RS17905	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C6W76_RS17910	COG0644	oxidoreductase
C6W76_RS17965	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C6W76_RS17970	COG0505	Belongs to the CarA family
C6W76_RS17995	COG1047	Peptidyl-prolyl cis-trans
C6W76_RS18010	COG0196	riboflavin kinase activity
C6W76_RS18045	COG0583	DNA-binding transcription factor activity
C6W76_RS18075	COG4735	regulation of single-species biofilm formation
C6W76_RS18080	COG1584	GPR1 FUN34 yaaH family protein
C6W76_RS18085	COG0521	Mo-molybdopterin cofactor biosynthetic process
C6W76_RS18095	COG1115	amino acid carrier protein
C6W76_RS18110	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C6W76_RS18120	COG0460	homoserine dehydrogenase
C6W76_RS18120	COG0527	aspartate kinase activity
C6W76_RS18130	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
C6W76_RS18140	COG0745	RESPONSE REGULATOR receiver
C6W76_RS18145	COG4452	Inner membrane protein CreD
C6W76_RS18150	COG2205	protein histidine kinase activity
C6W76_RS18155	COG0745	RESPONSE REGULATOR receiver
C6W76_RS18160	COG3045	CreA protein
C6W76_RS18165	COG3708	Transcriptional regulator
C6W76_RS18165	COG2207	Transcriptional regulator
C6W76_RS18185	COG0741	lytic transglycosylase activity
C6W76_RS18195	COG0488	(ABC) transporter
C6W76_RS18200	COG3172	ATPase kinase involved in NAD metabolism
C6W76_RS18200	COG1056	cytidyltransferase-related domain
C6W76_RS18205	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C6W76_RS18210	COG0560	Phosphoserine phosphatase
C6W76_RS18215	COG3726	membrane protein affecting hemolysin expression
C6W76_RS18245	COG1328	CTP reductase activity
C6W76_RS18250	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C6W76_RS18255	COG0084	hydrolase, TatD family'
C6W76_RS18260	COG4667	esterase of the alpha-beta hydrolase superfamily
C6W76_RS18270	COG2823	Periplasmic or secreted lipoprotein
C6W76_RS18280	COG1011	Hydrolase
C6W76_RS18285	COG0456	acetyltransferase
C6W76_RS18290	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
C6W76_RS18320	COG4114	ferric iron reductase
C6W76_RS18325	COG2197	response regulator
C6W76_RS18330	COG2197	response regulator
C6W76_RS18335	COG2966	Psort location CytoplasmicMembrane, score
C6W76_RS18350	COG1484	DNA-dependent DNA replication
C6W76_RS18365	COG1063	alcohol dehydrogenase
C6W76_RS18370	COG1802	Transcriptional regulator
C6W76_RS18375	COG2271	Major facilitator Superfamily
C6W76_RS18380	COG0840	transmembrane signaling receptor activity
C6W76_RS18385	COG1846	Transcriptional regulator
C6W76_RS18395	COG1012	belongs to the aldehyde dehydrogenase family
C6W76_RS18400	COG3384	dioxygenase
C6W76_RS18410	COG3971	2-oxopent-4-enoate hydratase activity
C6W76_RS18430	COG2368	4-hydroxyphenylacetate
C6W76_RS18435	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C6W76_RS18445	COG1966	Carbon starvation protein
C6W76_RS18450	COG2879	small protein
C6W76_RS18455	COG0523	cobalamin synthesis protein
C6W76_RS18465	COG5457	Domain of unknown function (DUF1127)
C6W76_RS18470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C6W76_RS18480	COG2814	Major facilitator Superfamily
C6W76_RS18485	COG2733	membrane
C6W76_RS18490	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
C6W76_RS18495	COG1924	4 iron, 4 sulfur cluster binding
C6W76_RS18510	COG0477	Major facilitator Superfamily
C6W76_RS18525	COG3366	ferrous iron transmembrane transporter activity
C6W76_RS18530	COG0700	Nucleoside recognition
C6W76_RS18535	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C6W76_RS18540	COG0583	DNA-binding transcription factor activity
C6W76_RS18560	COG2186	Transcriptional regulator
C6W76_RS18570	COG0246	Mannitol dehydrogenase
C6W76_RS18585	COG2610	gluconate transmembrane transporter activity
C6W76_RS18590	COG3539	Fimbrial protein
C6W76_RS18595	COG3539	Fimbrial protein
C6W76_RS18600	COG3539	Fimbrial protein
C6W76_RS18605	COG3188	usher protein
C6W76_RS18610	COG3121	Chaperone
C6W76_RS18615	COG3539	Fimbrial protein
C6W76_RS18620	COG3539	Fimbrial protein
C6W76_RS18630	COG4974	Belongs to the 'phage' integrase family
C6W76_RS18635	COG0582	viral genome integration into host DNA
C6W76_RS18650	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
C6W76_RS18655	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
C6W76_RS18685	COG1715	Restriction endonuclease
C6W76_RS18700	COG2003	Belongs to the UPF0758 family
C6W76_RS18725	COG2378	regulation of single-species biofilm formation
C6W76_RS18735	COG2378	regulation of single-species biofilm formation
C6W76_RS18745	COG3596	GTP binding
C6W76_RS18800	COG2255	four-way junction helicase activity
C6W76_RS18810	COG0582	viral genome integration into host DNA
C6W76_RS18820	COG1064	alcohol dehydrogenase
C6W76_RS18825	COG3265	gluconokinase activity
C6W76_RS18830	COG1063	alcohol dehydrogenase
C6W76_RS18835	COG1028	Short-chain dehydrogenase reductase Sdr
C6W76_RS18840	COG2610	gluconate transmembrane transporter activity
C6W76_RS18845	COG1609	Transcriptional regulator
C6W76_RS18855	COG0795	lipopolysaccharide-transporting ATPase activity
C6W76_RS18860	COG0795	lipopolysaccharide-transporting ATPase activity
C6W76_RS18870	COG2927	DNA polymerase III (CHI subunit)
C6W76_RS18875	COG0525	valine-tRNA ligase activity
C6W76_RS18885	COG0456	acetyltransferase
C6W76_RS18890	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
C6W76_RS18905	COG2731	YhcH YjgK YiaL family protein
C6W76_RS18910	COG1309	transcriptional regulator
C6W76_RS18915	COG1028	Short-chain dehydrogenase reductase Sdr
C6W76_RS18945	COG0251	oxidation-reduction process
C6W76_RS18950	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C6W76_RS18960	COG1609	Transcriptional regulator
C6W76_RS18965	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6W76_RS18965	COG1263	PTS System
C6W76_RS18970	COG0366	Alpha amylase catalytic
C6W76_RS18975	COG1328	CTP reductase activity
C6W76_RS18980	COG0602	queuosine metabolic process
C6W76_RS18985	COG3783	Cytochrome b(562)
C6W76_RS18990	COG0312	modulator of DNA gyrase
C6W76_RS19000	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C6W76_RS19010	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6W76_RS19015	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6W76_RS19020	COG1129	ABC transporter
C6W76_RS19025	COG1879	ABC-type sugar transport system periplasmic component
C6W76_RS19030	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
C6W76_RS19035	COG2105	PFAM AIG2 family protein
C6W76_RS19040	COG2911	Protein conserved in bacteria
C6W76_RS19045	COG0729	surface antigen
C6W76_RS19060	COG1253	flavin adenine dinucleotide binding
C6W76_RS19070	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
C6W76_RS19085	COG1218	3'(2'),5'-bisphosphate nucleotidase
C6W76_RS19090	COG0737	Belongs to the 5'-nucleotidase family
C6W76_RS19095	COG1733	regulation of RNA biosynthetic process
C6W76_RS19100	COG0702	epimerase
C6W76_RS19105	COG0697	spore germination
C6W76_RS19115	COG1113	amino acid transport
C6W76_RS19120	COG0545	Peptidyl-prolyl cis-trans isomerase
C6W76_RS19130	COG3061	Opacity-associated protein A
C6W76_RS19135	COG1309	transcriptional regulator
C6W76_RS19150	COG1024	Enoyl-CoA hydratase
C6W76_RS19155	COG4670	ketone body catabolic process
C6W76_RS19160	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C6W76_RS19165	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
C6W76_RS19175	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C6W76_RS19185	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C6W76_RS19205	COG3477	response to acidic pH
C6W76_RS19235	COG3037	sugar-specific permease SgaT UlaA
C6W76_RS19250	COG1073	alpha beta
C6W76_RS19255	COG3650	response to hydrogen peroxide
C6W76_RS19265	COG1960	acyl-CoA dehydrogenase activity
C6W76_RS19270	COG0754	glutathionylspermidine amidase activity
C6W76_RS19275	COG5463	Belongs to the UPF0441 family
C6W76_RS19280	COG3766	membrane
C6W76_RS19290	COG1842	Phage shock protein A
C6W76_RS19295	COG3789	protein conserved in bacteria
C6W76_RS19305	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C6W76_RS19310	COG0557	exoribonuclease II activity
C6W76_RS19325	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
C6W76_RS19330	COG0330	HflC and HflK could
C6W76_RS19335	COG0330	HflC and HflK could
C6W76_RS19340	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C6W76_RS19360	COG0860	N-Acetylmuramoyl-L-alanine amidase
C6W76_RS19365	COG0802	atpase or kinase
C6W76_RS19370	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C6W76_RS19370	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C6W76_RS19375	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C6W76_RS19415	COG3264	Mechanosensitive ion channel
C6W76_RS19415	COG1511	domain protein
C6W76_RS19420	COG0531	amino acid
C6W76_RS19430	COG1053	succinate dehydrogenase
C6W76_RS19435	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C6W76_RS19455	COG3040	lipid binding
C6W76_RS19460	COG2076	Multidrug Resistance protein
C6W76_RS19465	COG5510	response to toxic substance
C6W76_RS19470	COG5510	response to toxic substance
C6W76_RS19480	COG1509	lysine 2,3-aminomutase activity
C6W76_RS19505	COG0531	amino acid
C6W76_RS19510	COG3030	protein affecting phage T7 exclusion by the F plasmid
C6W76_RS19515	COG1027	Aspartate ammonia-lyase
C6W76_RS19520	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C6W76_RS19535	COG1309	transcriptional regulator
C6W76_RS19545	COG0582	viral genome integration into host DNA
C6W76_RS19615	COG3290	protein histidine kinase activity
C6W76_RS19620	COG4565	transcriptional regulatory protein
C6W76_RS19630	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C6W76_RS19635	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C6W76_RS19635	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C6W76_RS19640	COG3647	Membrane
C6W76_RS19655	COG1486	melibiose metabolic process
C6W76_RS19665	COG2169	Transcriptional regulator
C6W76_RS19675	COG2207	Transcriptional regulator
C6W76_RS19680	COG0531	amino acid
C6W76_RS19685	COG2194	sulfuric ester hydrolase activity
C6W76_RS19690	COG0745	RESPONSE REGULATOR receiver
C6W76_RS19695	COG0642	Histidine kinase
C6W76_RS19705	COG0477	Major facilitator Superfamily
C6W76_RS19715	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C6W76_RS19725	COG2824	Alkylphosphonate utilization operon protein PhnA
C6W76_RS19730	COG2764	glyoxalase bleomycin resistance protein dioxygenase
C6W76_RS19745	COG3639	organic phosphonate transmembrane transporter activity
C6W76_RS19750	COG2188	Transcriptional regulator
C6W76_RS19755	COG3624	Phosphonate C-P lyase system protein PhnG
C6W76_RS19760	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
C6W76_RS19765	COG3626	phosphonate metabolism
C6W76_RS19770	COG3627	carbon phosphorus lyase activity
C6W76_RS19775	COG4107	phosphonate C-P lyase system protein PhnK
C6W76_RS19780	COG4778	phosphonate C-P lyase system protein PhnL
C6W76_RS19785	COG3454	Phosphonate metabolism
C6W76_RS19790	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
C6W76_RS19795	COG0456	acetyltransferase
C6W76_RS19800	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C6W76_RS19810	COG0698	ribose 5-phosphate isomerase
C6W76_RS19815	COG2015	COG2015, Alkyl sulfatase and related hydrolases
C6W76_RS19825	COG1566	PFAM secretion protein HlyD family protein
C6W76_RS19845	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C6W76_RS19850	COG1301	dicarboxylic acid transport
C6W76_RS19860	COG4235	cytochrome complex assembly
C6W76_RS19865	COG3088	subunit of a heme lyase
C6W76_RS19870	COG1138	Cytochrome C-type biogenesis protein
C6W76_RS19875	COG3301	Polysulphide reductase, NrfD
C6W76_RS19880	COG0437	4 iron, 4 sulfur cluster binding
C6W76_RS19885	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
C6W76_RS19900	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C6W76_RS19905	COG3162	membrane
C6W76_RS19915	COG1357	PFAM Pentapeptide repeats (8 copies)
C6W76_RS19920	COG0025	NhaP-type Na H and K H
C6W76_RS19925	COG2252	PERMEase
C6W76_RS19945	COG0789	Transcriptional regulator
C6W76_RS19950	COG2207	Transcriptional regulator
C6W76_RS19955	COG4943	cyclic-guanylate-specific phosphodiesterase activity
C6W76_RS19970	COG0629	single-stranded DNA binding
C6W76_RS19975	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C6W76_RS19980	COG2315	Protein conserved in bacteria
C6W76_RS19985	COG0432	Pfam Uncharacterised protein family UPF0047
C6W76_RS19990	COG3700	Belongs to the class B bacterial acid phosphatase family
C6W76_RS20000	COG1448	Aminotransferase
C6W76_RS20005	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C6W76_RS20010	COG0305	Participates in initiation and elongation during chromosome replication
C6W76_RS20015	COG0604	alcohol dehydrogenase
C6W76_RS20025	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C6W76_RS20070	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6W76_RS20235	COG0582	viral genome integration into host DNA
C6W76_RS20285	COG3772	lysozyme
C6W76_RS20355	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C6W76_RS20370	COG0735	belongs to the Fur family
C6W76_RS20375	COG3237	CsbD-like
C6W76_RS20380	COG0534	Mate efflux family protein
C6W76_RS20390	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C6W76_RS20435	COG3842	ATPase activity
C6W76_RS20445	COG2182	Extracellular solute-binding protein
C6W76_RS20450	COG1175	transmembrane transport
C6W76_RS20455	COG3833	ABC-type maltose transport systems, permease component
C6W76_RS20460	COG2814	Major facilitator Superfamily
C6W76_RS20460	COG0477	Major facilitator Superfamily
C6W76_RS20475	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C6W76_RS20505	COG0527	aspartate kinase activity
C6W76_RS20560	COG1283	sodium-dependent phosphate transmembrane transporter activity
C6W76_RS20565	COG0646	methionine synthase
C6W76_RS20565	COG1410	methionine synthase
C6W76_RS20570	COG1414	Transcriptional regulator
C6W76_RS20585	COG2224	Isocitrate lyase
C6W76_RS20590	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C6W76_RS20600	COG0456	acetyltransferase
C6W76_RS20635	COG0151	Belongs to the GarS family
C6W76_RS20640	COG2204	response regulator
C6W76_RS20645	COG4191	Histidine kinase
C6W76_RS20655	COG3678	ATP-independent chaperone mediated protein folding
C6W76_RS20670	COG3068	Protein conserved in bacteria
C6W76_RS20710	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C6W76_RS20715	COG2104	thiamine diphosphate biosynthetic process
C6W76_RS20725	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
C6W76_RS20770	COG0250	Participates in transcription elongation, termination and antitermination
C6W76_RS20775	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C6W76_RS20820	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
C6W76_RS20820	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
C6W76_RS20860	COG4206	TonB-dependent receptor
C6W76_RS20890	COG0583	DNA-binding transcription factor activity
C6W76_RS20905	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C6W76_RS20920	COG2194	sulfuric ester hydrolase activity
C6W76_RS20925	COG2207	Transcriptional regulator
C6W76_RS20930	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6W76_RS20935	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C6W76_RS20950	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6W76_RS20960	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C6W76_RS20960	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6W76_RS20960	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6W76_RS20965	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6W76_RS20965	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6W76_RS20965	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C6W76_RS20970	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C6W76_RS20975	COG0371	Dehydrogenase
C6W76_RS20980	COG3738	Protein conserved in bacteria
C6W76_RS20985	COG0697	spore germination
C6W76_RS20995	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C6W76_RS21000	COG0527	aspartate kinase activity
C6W76_RS21000	COG0460	homoserine dehydrogenase
C6W76_RS21005	COG0626	cystathionine gamma-synthase activity
C6W76_RS21030	COG3209	COG3209 Rhs family protein
C6W76_RS21030	COG3209	COG3209 Rhs family protein
C6W76_RS21040	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C6W76_RS21045	COG1609	Transcriptional regulator
C6W76_RS21050	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C6W76_RS21065	COG1575	Belongs to the MenA family. Type 1 subfamily
C6W76_RS21080	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C6W76_RS21090	COG1494	fructose-1,6-bisphosphatase
C6W76_RS21100	COG0589	response to stress
C6W76_RS21105	COG3691	Protein conserved in bacteria
C6W76_RS21110	COG3152	Membrane
C6W76_RS21130	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C6W76_RS21145	COG3678	ATP-independent chaperone mediated protein folding
C6W76_RS21150	COG0745	RESPONSE REGULATOR receiver
C6W76_RS21155	COG2205	protein histidine kinase activity
C6W76_RS21160	COG2258	MOSC domain
C6W76_RS21175	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C6W76_RS21215	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6W76_RS21220	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6W76_RS21220	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6W76_RS21225	COG1363	Peptidase, m42
C6W76_RS21250	COG0243	molybdopterin cofactor binding
C6W76_RS21250	COG3383	formate dehydrogenase (NAD+) activity
C6W76_RS21255	COG0243	molybdopterin cofactor binding
C6W76_RS21255	COG3383	formate dehydrogenase (NAD+) activity
C6W76_RS21260	COG0437	4 iron, 4 sulfur cluster binding
C6W76_RS21265	COG2864	formate dehydrogenase
C6W76_RS21280	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C6W76_RS21285	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C6W76_RS21290	COG0456	acetyltransferase
C6W76_RS21305	COG1011	Hydrolase
C6W76_RS21310	COG1349	DNA-binding transcription factor activity
C6W76_RS21315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6W76_RS21320	COG2084	Dehydrogenase
C6W76_RS21325	COG3684	Belongs to the aldolase LacD family
C6W76_RS21330	COG2942	2-epimerase
C6W76_RS21335	COG2942	2-epimerase
C6W76_RS21340	COG2017	converts alpha-aldose to the beta-anomer
C6W76_RS21345	COG1501	Belongs to the glycosyl hydrolase 31 family
C6W76_RS21350	COG2211	Major facilitator Superfamily
C6W76_RS21355	COG2211	Major facilitator Superfamily
C6W76_RS21360	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
C6W76_RS21365	COG2271	Major facilitator Superfamily
C6W76_RS21370	COG1082	Xylose isomerase domain protein TIM barrel
C6W76_RS21375	COG2188	Transcriptional regulator
C6W76_RS21380	COG1217	gtp-binding protein TYPA
C6W76_RS21390	COG0174	glutamine synthetase
C6W76_RS21395	COG3852	Histidine kinase
C6W76_RS21400	COG2204	response regulator
C6W76_RS21410	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C6W76_RS21425	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C6W76_RS21425	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C6W76_RS21435	COG0204	Acyl-transferase
C6W76_RS21440	COG5339	Protein conserved in bacteria
C6W76_RS21445	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C6W76_RS21450	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C6W76_RS21455	COG3084	Protein conserved in bacteria
C6W76_RS21460	COG0746	molybdenum cofactor guanylyltransferase activity
C6W76_RS21465	COG1763	Mo-molybdopterin cofactor biosynthetic process
C6W76_RS21495	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
C6W76_RS21500	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C6W76_RS21505	COG1739	Uncharacterized protein family UPF0029
C6W76_RS21525	COG0543	2 iron, 2 sulfur cluster binding
C6W76_RS21530	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C6W76_RS21535	COG0250	Participates in transcription elongation, termination and antitermination
C6W76_RS21545	COG0805	protein transport
C6W76_RS21550	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C6W76_RS21555	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C6W76_RS21565	COG3165	ubiquinone biosynthetic process from chorismate
C6W76_RS21575	COG1322	Protein conserved in bacteria
C6W76_RS21580	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
C6W76_RS21585	COG0412	Dienelactone hydrolase
C6W76_RS21595	COG0583	DNA-binding transcription factor activity
C6W76_RS21600	COG0697	spore germination
C6W76_RS21605	COG0561	phosphatase activity
C6W76_RS21610	COG2267	carboxylic ester hydrolase activity
C6W76_RS21615	COG1280	lysine exporter protein (LysE YggA)
C6W76_RS21620	COG1280	lysine exporter protein (LysE YggA)
C6W76_RS21625	COG0514	ATP-dependent DNA helicase (RecQ)
C6W76_RS21630	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
C6W76_RS21635	COG2050	protein possibly involved in aromatic compounds catabolism
C6W76_RS21640	COG2962	Rard protein
C6W76_RS21670	COG0598	Magnesium transport protein CorA
C6W76_RS21675	COG3698	Phosphodiester glycosidase
C6W76_RS21680	COG0210	DNA helicase
C6W76_RS21685	COG1011	Hydrolase
C6W76_RS21695	COG3159	Protein conserved in bacteria
C6W76_RS21705	COG5567	small periplasmic lipoprotein
C6W76_RS21715	COG3072	Adenylate cyclase
C6W76_RS21730	COG1587	Uroporphyrinogen-III synthase
C6W76_RS21735	COG2959	enzyme of heme biosynthesis
C6W76_RS21740	COG3071	HemY protein
C6W76_RS21745	COG0641	radical SAM
C6W76_RS21770	COG1113	amino acid transport
C6W76_RS21790	COG2244	polysaccharide biosynthetic process
C6W76_RS21795	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C6W76_RS21800	COG0456	acetyltransferase
C6W76_RS21805	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C6W76_RS21810	COG1088	dTDP-glucose 4,6-dehydratase activity
C6W76_RS21815	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
C6W76_RS21820	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C6W76_RS21825	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
C6W76_RS21830	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C6W76_RS21840	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C6W76_RS21850	COG3118	belongs to the thioredoxin family
C6W76_RS21870	COG0210	DNA helicase
C6W76_RS21875	COG3692	DNA binding
C6W76_RS21880	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C6W76_RS21890	COG0583	DNA-binding transcription factor activity
C6W76_RS21895	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C6W76_RS21905	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C6W76_RS21910	COG3978	acetolactate synthase activity
C6W76_RS21935	COG0606	chelatase, subunit chli
C6W76_RS21940	COG3085	chromosome segregation
C6W76_RS21985	COG2186	Transcriptional regulator
C6W76_RS21990	COG0477	Major facilitator Superfamily
C6W76_RS21995	COG1609	Transcriptional regulator
C6W76_RS22000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6W76_RS22005	COG1879	ABC-type sugar transport system periplasmic component
C6W76_RS22010	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6W76_RS22015	COG1129	ABC transporter
C6W76_RS22045	COG1522	sequence-specific DNA binding
C6W76_RS22050	COG0716	FMN binding
C6W76_RS22065	COG3312	ion transport
C6W76_RS22130	COG3188	usher protein
C6W76_RS22135	COG3539	Fimbrial protein
C6W76_RS22140	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C6W76_RS22145	COG0573	inorganic phosphate transmembrane transporter activity
C6W76_RS22150	COG0581	inorganic phosphate transmembrane transporter activity
C6W76_RS22155	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C6W76_RS22160	COG0704	Plays a role in the regulation of phosphate uptake
C6W76_RS22165	COG3711	transcriptional antiterminator
C6W76_RS22170	COG2190	(PTS) system
C6W76_RS22170	COG1263	PTS System
C6W76_RS22170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6W76_RS22175	COG2723	6-phospho-beta-galactosidase activity
C6W76_RS22190	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C6W76_RS22195	COG2252	PERMEase
C6W76_RS22200	COG0431	NADPH-dependent FMN reductase
C6W76_RS22205	COG2091	lysine biosynthetic process via aminoadipic acid
C6W76_RS22220	COG0814	amino acid
C6W76_RS22270	COG0592	DNA-directed DNA polymerase activity
C6W76_RS22280	COG0187	DNA topoisomerase II activity
C6W76_RS22285	COG3753	Protein conserved in bacteria
C6W76_RS22290	COG0561	phosphatase activity
C6W76_RS22300	COG2186	Transcriptional regulator
C6W76_RS22305	COG3734	2-keto-3-deoxy-galactonokinase
C6W76_RS22310	COG0800	Aldolase
C6W76_RS22320	COG2271	Major facilitator Superfamily
C6W76_RS22330	COG0823	Involved in the tonB-independent uptake of proteins
C6W76_RS22335	COG5645	(Lipo)protein
C6W76_RS22355	COG2188	Transcriptional regulator
C6W76_RS22370	COG2207	Transcriptional regulator
C6W76_RS22375	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C6W76_RS22390	COG2149	membrane
C6W76_RS22400	COG0641	radical SAM
C6W76_RS22405	COG2814	Major facilitator Superfamily
C6W76_RS22440	COG0028	Belongs to the TPP enzyme family
C6W76_RS22445	COG0440	acetolactate synthase activity
C6W76_RS22450	COG2197	response regulator
C6W76_RS22455	COG3851	Histidine kinase
C6W76_RS22460	COG2271	Major facilitator Superfamily
C6W76_RS22465	COG2271	Major facilitator Superfamily
C6W76_RS22475	COG2252	PERMEase
C6W76_RS22505	COG1464	Belongs to the NlpA lipoprotein family
C6W76_RS22510	COG0697	spore germination
C6W76_RS22515	COG2814	Major facilitator Superfamily
C6W76_RS22585	COG0582	viral genome integration into host DNA
C6W76_RS22595	COG2211	Major facilitator Superfamily
C6W76_RS22600	COG1501	Belongs to the glycosyl hydrolase 31 family
C6W76_RS22605	COG2982	Protein involved in outer membrane biogenesis
C6W76_RS22610	COG2233	PERMEase
C6W76_RS22615	COG0786	glutamate:sodium symporter activity
C6W76_RS22625	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C6W76_RS22630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C6W76_RS22635	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C6W76_RS22645	COG0194	GDP metabolic process
C6W76_RS22655	COG2860	membrane
C6W76_RS22660	COG3645	SOS response
C6W76_RS22680	COG2391	methyltransferase activity
C6W76_RS22760	COG1561	YicC-like family, N-terminal region
C6W76_RS22790	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C6W76_RS22820	COG1519	Transferase
C6W76_RS22825	COG0859	PFAM glycosyl transferase family 9
C6W76_RS22830	COG0438	transferase activity, transferring glycosyl groups
C6W76_RS22835	COG0515	serine threonine protein kinase
C6W76_RS22845	COG3642	lipopolysaccharide core region biosynthetic process
C6W76_RS22865	COG0859	PFAM glycosyl transferase family 9
C6W76_RS22870	COG0859	PFAM glycosyl transferase family 9
C6W76_RS22885	COG0156	8-amino-7-oxononanoate synthase activity
C6W76_RS22895	COG1216	Glycosyl transferase, family 2
C6W76_RS22900	COG2861	carbohydrate metabolic process
C6W76_RS22905	COG4942	peptidase
C6W76_RS22920	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C6W76_RS22925	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C6W76_RS22940	COG1045	serine acetyltransferase
C6W76_RS22945	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C6W76_RS22955	COG2186	Transcriptional regulator
C6W76_RS22960	COG1620	l-lactate permease
C6W76_RS22995	COG3722	fumarate hydratase activity
C6W76_RS23005	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6W76_RS23005	COG2213	PTS system mannitol-specific
C6W76_RS23015	COG1566	PFAM secretion protein HlyD family protein
C6W76_RS23035	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C6W76_RS23040	COG3209	COG3209 Rhs family protein
C6W76_RS23045	COG0625	glutathione transferase activity
C6W76_RS23055	COG3276	selenocysteine insertion sequence binding
C6W76_RS23060	COG1454	alcohol dehydrogenase
C6W76_RS23065	COG1012	belongs to the aldehyde dehydrogenase family
C6W76_RS23080	COG1566	PFAM secretion protein HlyD family protein
C6W76_RS23085	COG1566	PFAM secretion protein HlyD family protein
C6W76_RS23090	COG0583	DNA-binding transcription factor activity
C6W76_RS23095	COG3713	MltA-interacting MipA family protein
C6W76_RS23105	COG0235	Class ii aldolase
C6W76_RS23110	COG3623	hexulose-6-phosphate isomerase
C6W76_RS23115	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
C6W76_RS23120	COG1070	Carbohydrate kinase
C6W76_RS23125	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C6W76_RS23130	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
C6W76_RS23135	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
C6W76_RS23140	COG2731	YhcH YjgK YiaL family protein
C6W76_RS23150	COG1414	Transcriptional regulator
C6W76_RS23155	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6W76_RS23160	COG3977	Valine--pyruvate aminotransferase
C6W76_RS23165	COG0366	Alpha amylase catalytic
C6W76_RS23170	COG2992	FlgJ-related protein
C6W76_RS23175	COG2207	Transcriptional regulator
C6W76_RS23175	COG1609	Transcriptional regulator
C6W76_RS23180	COG4214	carbohydrate transport
C6W76_RS23190	COG4213	ABC transporter substrate-binding protein
C6W76_RS23200	COG1070	Carbohydrate kinase
C6W76_RS23205	COG4682	membrane
C6W76_RS23210	COG4682	membrane
C6W76_RS23215	COG3274	enterobacterial common antigen metabolic process
C6W76_RS23240	COG1278	Cold shock
C6W76_RS23245	COG2944	sequence-specific DNA binding
C6W76_RS23260	COG2885	chlorophyll binding
C6W76_RS23265	COG0243	molybdopterin cofactor binding
C6W76_RS23270	COG0456	acetyltransferase
C6W76_RS23275	COG2818	Glycosylase
C6W76_RS23280	COG5571	outer membrane autotransporter
C6W76_RS23290	COG2223	nitrite transmembrane transporter activity
C6W76_RS23295	COG2194	sulfuric ester hydrolase activity
C6W76_RS23315	COG0747	negative chemotaxis
C6W76_RS23320	COG0601	transmembrane transport
C6W76_RS23325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C6W76_RS23330	COG0444	Belongs to the ABC transporter superfamily
C6W76_RS23335	COG4608	Belongs to the ABC transporter superfamily
C6W76_RS23340	COG0814	amino acid
C6W76_RS23375	COG2194	sulfuric ester hydrolase activity
C6W76_RS23400	COG1215	transferase activity, transferring glycosyl groups
C6W76_RS23405	COG1215	transferase activity, transferring glycosyl groups
C6W76_RS23410	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
C6W76_RS23420	COG2199	diguanylate cyclase activity
C6W76_RS23420	COG2200	EAL domain
C6W76_RS23435	COG0612	Peptidase, M16
C6W76_RS23450	COG2200	EAL domain
C6W76_RS23455	COG2982	Protein involved in outer membrane biogenesis
C6W76_RS23460	COG0477	Major facilitator Superfamily
C6W76_RS23465	COG1295	ribonuclease BN
C6W76_RS23470	COG0583	DNA-binding transcription factor activity
C6W76_RS23475	COG2197	response regulator
C6W76_RS23485	COG1858	cytochrome C peroxidase
C6W76_RS23490	COG0076	glutamate decarboxylase activity
C6W76_RS23500	COG2207	Transcriptional regulator
C6W76_RS23510	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C6W76_RS23515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6W76_RS23525	COG2771	luxR family
C6W76_RS23530	COG3247	response to pH
C6W76_RS23545	COG1285	pathogenesis
C6W76_RS23550	COG2197	response regulator
C6W76_RS23560	COG3065	identical protein binding
C6W76_RS23580	COG1393	Belongs to the ArsC family
C6W76_RS23585	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C6W76_RS23590	COG0640	Transcriptional regulator
C6W76_RS23605	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C6W76_RS23610	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
C6W76_RS23615	COG0339	signal peptide processing
C6W76_RS23625	COG3104	oligopeptide transport
C6W76_RS23640	COG0589	response to stress
C6W76_RS23650	COG0306	phosphate transporter
C6W76_RS23655	COG2081	HI0933 family
C6W76_RS23680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6W76_RS23685	COG0842	Transport permease protein
C6W76_RS23685	COG1129	ABC transporter
C6W76_RS23690	COG0842	Transport permease protein
C6W76_RS23715	COG0444	Belongs to the ABC transporter superfamily
C6W76_RS23720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C6W76_RS23725	COG0601	transmembrane transport
C6W76_RS23730	COG0747	negative chemotaxis
C6W76_RS23735	COG2091	lysine biosynthetic process via aminoadipic acid
C6W76_RS23740	COG0628	permease
C6W76_RS23755	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C6W76_RS23770	COG3714	YhhN family
C6W76_RS23780	COG3776	membrane
C6W76_RS23785	COG0742	ribosomal rna small subunit methyltransferase
C6W76_RS23790	COG0552	protein localization to endoplasmic reticulum
C6W76_RS23795	COG2884	Cell division ATP-binding protein ftsE
C6W76_RS23800	COG2177	Part of the ABC transporter FtsEX involved in
C6W76_RS23805	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C6W76_RS23810	COG0683	leucine binding
C6W76_RS23815	COG0456	acetyltransferase
C6W76_RS23820	COG0683	leucine binding
C6W76_RS23825	COG0559	Belongs to the binding-protein-dependent transport system permease family
C6W76_RS23830	COG4177	L-phenylalanine transmembrane transporter activity
C6W76_RS23835	COG0411	ABC transporter
C6W76_RS23840	COG0410	ABC transporter
C6W76_RS23845	COG1653	transport
C6W76_RS23865	COG0584	glycerophosphoryl diester phosphodiesterase
C6W76_RS23875	COG0405	Gamma-glutamyltransferase
C6W76_RS23895	COG3157	Type VI secretion system effector, Hcp
C6W76_RS23900	COG1247	-acetyltransferase
C6W76_RS23910	COG0673	inositol 2-dehydrogenase activity
C6W76_RS23915	COG1741	Belongs to the pirin family
C6W76_RS23920	COG1609	Transcriptional regulator
C6W76_RS23925	COG3265	gluconokinase activity
C6W76_RS23930	COG2610	gluconate transmembrane transporter activity
C6W76_RS23935	COG2095	MarC family integral membrane protein
C6W76_RS23940	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C6W76_RS23965	COG0058	SHG alpha-glucan phosphorylase activity
C6W76_RS23970	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C6W76_RS23990	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C6W76_RS24005	COG1349	DNA-binding transcription factor activity
C6W76_RS24010	COG4650	regulator
C6W76_RS24015	COG1690	Belongs to the RtcB family
C6W76_RS24030	COG0058	SHG alpha-glucan phosphorylase activity
C6W76_RS24035	COG1640	4-alpha-glucanotransferase
C6W76_RS24040	COG2610	gluconate transmembrane transporter activity
C6W76_RS24060	COG5464	transposase or invertase
C6W76_RS24075	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
C6W76_RS24080	COG1918	ferrous iron import across plasma membrane
C6W76_RS24090	COG2183	response to ionizing radiation
C6W76_RS24095	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C6W76_RS24125	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
C6W76_RS24135	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C6W76_RS24140	COG1011	Hydrolase
C6W76_RS24150	COG0494	nUDIX hydrolase
C6W76_RS24155	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
C6W76_RS24160	COG4972	Pilus assembly protein
C6W76_RS24165	COG3166	PFAM Fimbrial assembly family protein
C6W76_RS24180	COG4796	Type ii and iii secretion system protein
C6W76_RS24200	COG3266	domain, Protein
C6W76_RS24205	COG0338	D12 class N6 adenine-specific DNA methyltransferase
C6W76_RS24210	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C6W76_RS24220	COG0180	Tryptophanyl-tRNA synthetase
C6W76_RS24225	COG2188	Transcriptional regulator
C6W76_RS24235	COG3457	Alanine racemase
C6W76_RS24240	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
C6W76_RS24245	COG1735	metal-dependent hydrolase with the TIM-barrel fold
C6W76_RS24260	COG0626	cystathionine gamma-synthase activity
C6W76_RS24265	COG2188	Transcriptional regulator
C6W76_RS24275	COG1082	Xylose isomerase domain protein TIM barrel
C6W76_RS24285	COG2222	sugar isomerase
C6W76_RS24290	COG0531	amino acid
C6W76_RS24305	COG2116	formate transmembrane transporter activity
C6W76_RS24310	COG2146	nitrite reductase [NAD(P)H] activity
C6W76_RS24315	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C6W76_RS24325	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C6W76_RS24335	COG2184	nucleotidyltransferase activity
C6W76_RS24340	COG0512	Glutamine amidotransferase of anthranilate synthase
C6W76_RS24350	COG1289	transmembrane transporter activity
C6W76_RS24355	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C6W76_RS24365	COG1765	OsmC-like protein
C6W76_RS24370	COG3954	Phosphoribulokinase
C6W76_RS24380	COG0429	hydrolase of the alpha beta-hydrolase fold
C6W76_RS24385	COG0488	(ABC) transporter
C6W76_RS24405	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
C6W76_RS24410	COG1047	Peptidyl-prolyl cis-trans
C6W76_RS24420	COG0545	Peptidyl-prolyl cis-trans isomerase
C6W76_RS24425	COG2964	Protein conserved in bacteria
C6W76_RS24505	COG0089	rRNA binding
C6W76_RS24595	COG0201	protein transport
C6W76_RS24635	COG0789	Transcriptional regulator
C6W76_RS24640	COG3036	rescue of stalled ribosome
C6W76_RS24650	COG0569	domain protein
C6W76_RS24680	COG0551	DNA topoisomerase type I activity
C6W76_RS24700	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C6W76_RS24740	COG1126	abc transporter atp-binding protein
C6W76_RS24745	COG0765	amino acid transport
C6W76_RS24755	COG4597	amino acid ABC transporter
C6W76_RS24760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6W76_RS24780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6W76_RS24790	COG1309	transcriptional regulator
C6W76_RS24800	COG2189	Belongs to the N(4) N(6)-methyltransferase family
C6W76_RS24810	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C6W76_RS24820	COG4145	pantothenate transmembrane transporter activity
C6W76_RS24825	COG3924	membrane
C6W76_RS24830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6W76_RS24835	COG1349	DNA-binding transcription factor activity
C6W76_RS24845	COG1879	ABC-type sugar transport system periplasmic component
C6W76_RS24850	COG1129	ABC transporter
C6W76_RS24855	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6W76_RS24860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6W76_RS24870	COG0439	Biotin carboxylase
C6W76_RS24875	COG0511	ligase activity, forming carbon-carbon bonds
C6W76_RS24890	COG0604	alcohol dehydrogenase
C6W76_RS24895	COG2199	diguanylate cyclase activity
C6W76_RS24895	COG2200	EAL domain
C6W76_RS24910	COG1077	Cell shape determining protein MreB Mrl
C6W76_RS24915	COG1792	Involved in formation and maintenance of cell shape
C6W76_RS24920	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C6W76_RS24930	COG1530	ribonuclease E activity
C6W76_RS24935	COG3164	Protein of unknown function
C6W76_RS24940	COG0312	modulator of DNA gyrase
C6W76_RS24945	COG0583	DNA-binding transcription factor activity
C6W76_RS24965	COG2732	(Barnase) inhibitor
C6W76_RS24985	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C6W76_RS24990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C6W76_RS24995	COG3105	Protein conserved in bacteria
C6W76_RS25000	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
C6W76_RS25030	COG0625	glutathione transferase activity
C6W76_RS25035	COG2969	positive regulation of protein catabolic process
C6W76_RS25040	COG3069	C4-dicarboxylate transmembrane transporter activity
C6W76_RS25075	COG2731	YhcH YjgK YiaL family protein
C6W76_RS25085	COG4804	nuclease activity
C6W76_RS25090	COG0493	'glutamate synthase
C6W76_RS25095	COG0069	glutamate synthase activity
C6W76_RS25095	COG0070	glutamate synthase
C6W76_RS25095	COG0067	glutamate synthase
C6W76_RS25110	COG1242	4 iron, 4 sulfur cluster binding
C6W76_RS25115	COG2198	Histidine kinase
C6W76_RS25115	COG0784	Response regulator, receiver
C6W76_RS25115	COG5002	protein histidine kinase activity
C6W76_RS25120	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
C6W76_RS25130	COG0515	serine threonine protein kinase
C6W76_RS25135	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6W76_RS25150	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C6W76_RS25155	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C6W76_RS25160	COG1137	ATPase activity
C6W76_RS25165	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
C6W76_RS25170	COG3117	lipopolysaccharide transmembrane transporter activity
C6W76_RS25175	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
C6W76_RS25180	COG0517	IMP dehydrogenase activity
C6W76_RS25180	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C6W76_RS25185	COG0530	calcium, potassium:sodium antiporter activity
C6W76_RS25190	COG1127	ABC transporter
C6W76_RS25195	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C6W76_RS25200	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C6W76_RS25205	COG2854	intermembrane phospholipid transfer
C6W76_RS25210	COG3113	response to antibiotic
C6W76_RS25215	COG5007	Belongs to the BolA IbaG family
C6W76_RS25225	COG3423	Transcriptional regulator
C6W76_RS25230	COG0142	geranyltranstransferase activity
C6W76_RS25245	COG0697	spore germination
C6W76_RS25255	COG2027	D-alanyl-D-alanine carboxypeptidase
C6W76_RS25260	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C6W76_RS25265	COG1534	Rna-binding protein
C6W76_RS25275	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C6W76_RS25280	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C6W76_RS25290	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C6W76_RS25320	COG0195	Participates in both transcription termination and antitermination
C6W76_RS25360	COG0513	Belongs to the DEAD box helicase family
C6W76_RS25365	COG0814	amino acid
C6W76_RS25370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C6W76_RS25375	COG0826	peptidase U32
C6W76_RS25380	COG0826	peptidase U32
C6W76_RS25385	COG3154	lipid carrier protein
C6W76_RS25390	COG3153	acetyltransferase
C6W76_RS25405	COG0693	protein deglycase activity
C6W76_RS25410	COG0702	epimerase
C6W76_RS25415	COG0701	Predicted permease
C6W76_RS25420	COG2823	Periplasmic or secreted lipoprotein
C6W76_RS25440	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C6W76_RS25445	COG3539	Fimbrial protein
C6W76_RS25465	COG3188	usher protein
C6W76_RS25470	COG3121	Chaperone
C6W76_RS25475	COG3539	Fimbrial protein
C6W76_RS25480	COG0363	glucosamine-6-phosphate deaminase activity
C6W76_RS25485	COG3716	PTS system mannose fructose sorbose family IID component
C6W76_RS25490	COG3715	PTS system
C6W76_RS25495	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6W76_RS25505	COG2222	sugar isomerase
C6W76_RS25510	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C6W76_RS25515	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6W76_RS25520	COG3716	PTS system mannose fructose sorbose family IID component
C6W76_RS25530	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6W76_RS25545	COG1349	DNA-binding transcription factor activity
C6W76_RS25555	COG2002	toxin-antitoxin pair type II binding
C6W76_RS25560	COG2721	sulfolactate sulfo-lyase activity
C6W76_RS25565	COG2271	Major facilitator Superfamily
C6W76_RS25575	COG2084	Dehydrogenase
C6W76_RS25580	COG1929	Belongs to the glycerate kinase type-1 family
C6W76_RS25605	COG0583	DNA-binding transcription factor activity
C6W76_RS25615	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C6W76_RS25625	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C6W76_RS25630	COG1882	Formate acetyltransferase
C6W76_RS25635	COG0251	oxidation-reduction process
C6W76_RS25640	COG1760	l-serine dehydratase
C6W76_RS25650	COG0814	amino acid
C6W76_RS25665	COG1741	Belongs to the pirin family
C6W76_RS25670	COG0583	DNA-binding transcription factor activity
C6W76_RS25680	COG3152	Membrane
C6W76_RS25685	COG3152	Membrane
C6W76_RS25690	COG0435	Glutathione S-transferase
C6W76_RS25695	COG2259	Doxx family
C6W76_RS25705	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
C6W76_RS25710	COG4575	ribosome binding
C6W76_RS25715	COG1422	Protein of unknown function (DUF1090)
C6W76_RS25725	COG0586	Pfam SNARE associated Golgi protein
C6W76_RS25730	COG2186	Transcriptional regulator
C6W76_RS25760	COG2271	Major facilitator Superfamily
C6W76_RS25770	COG2721	sulfolactate sulfo-lyase activity
C6W76_RS25780	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
C6W76_RS25790	COG0861	Integral membrane protein TerC family
C6W76_RS25795	COG0673	inositol 2-dehydrogenase activity
C6W76_RS25800	COG2949	membrane
C6W76_RS25805	COG1451	nucleotide metabolic process
C6W76_RS25820	COG4680	protein conserved in bacteria
C6W76_RS25825	COG5499	transcription regulator containing HTH domain
C6W76_RS25830	COG0446	pyridine nucleotide-disulphide oxidoreductase
C6W76_RS25830	COG1902	pentaerythritol trinitrate reductase activity
C6W76_RS25845	COG0531	amino acid
C6W76_RS25850	COG2731	YhcH YjgK YiaL family protein
C6W76_RS25855	COG3250	beta-galactosidase activity
C6W76_RS25860	COG1609	Transcriptional regulator
C6W76_RS25870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C6W76_RS25885	COG0840	transmembrane signaling receptor activity
C6W76_RS25890	COG1695	Transcriptional regulator
C6W76_RS25900	COG2375	cellular response to nickel ion
C6W76_RS25915	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C6W76_RS25925	COG0358	DNA primase activity
C6W76_RS25930	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C6W76_RS25945	COG0471	metal ion transport
C6W76_RS25950	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C6W76_RS25955	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C6W76_RS25965	COG0583	DNA-binding transcription factor activity
C6W76_RS25975	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C6W76_RS25990	COG4991	sh3 domain protein
C6W76_RS26000	COG3025	triphosphatase activity
C6W76_RS26030	COG2268	Band 7 protein
C6W76_RS26035	COG1585	Membrane protein implicated in regulation of membrane protease activity
C6W76_RS26045	COG3539	Fimbrial protein
C6W76_RS26055	COG3188	usher protein
C6W76_RS26060	COG3539	Fimbrial protein
C6W76_RS26065	COG2960	long-chain fatty acid transporting porin activity
C6W76_RS26085	COG3384	dioxygenase
C6W76_RS26090	COG0754	glutathionylspermidine amidase activity
C6W76_RS26105	COG1538	Outer membrane efflux protein
C6W76_RS26110	COG0494	nUDIX hydrolase
C6W76_RS26115	COG3151	Protein conserved in bacteria
C6W76_RS26120	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C6W76_RS26125	COG3150	esterase
C6W76_RS26130	COG0187	DNA topoisomerase II activity
C6W76_RS26135	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C6W76_RS26140	COG2249	NAD(P)H dehydrogenase (quinone) activity
C6W76_RS26155	COG0642	Histidine kinase
C6W76_RS26160	COG0745	RESPONSE REGULATOR receiver
C6W76_RS26165	COG3111	PFAM Bacterial OB fold (BOF) protein
C6W76_RS26170	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
C6W76_RS26180	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C6W76_RS26185	COG0204	Acyl-transferase
C6W76_RS26190	COG2132	Multicopper oxidase
C6W76_RS26195	COG1032	radical SAM domain protein
C6W76_RS26200	COG4238	major outer membrane lipoprotein
C6W76_RS26220	COG0656	L-ascorbic acid biosynthetic process
C6W76_RS26225	COG1979	alcohol dehydrogenase
C6W76_RS26230	COG2207	Transcriptional regulator
C6W76_RS26240	COG0626	cystathionine gamma-synthase activity
C6W76_RS26250	COG0811	peptide transport
C6W76_RS26255	COG0848	biopolymer transport protein
C6W76_RS26260	COG1028	Short-chain dehydrogenase reductase Sdr
C6W76_RS26270	COG0667	Aldo Keto reductase
C6W76_RS26290	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
C6W76_RS26295	COG0437	4 iron, 4 sulfur cluster binding
C6W76_RS26300	COG5557	Pfam Polysulphide reductase, NrfD
C6W76_RS26305	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
C6W76_RS26310	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C6W76_RS26315	COG1773	rubredoxin
C6W76_RS26325	COG0298	carbon dioxide binding
C6W76_RS26330	COG0625	glutathione transferase activity
C6W76_RS26335	COG0754	glutathionylspermidine amidase activity
C6W76_RS26350	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C6W76_RS26355	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C6W76_RS26360	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C6W76_RS26365	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C6W76_RS26370	COG2244	polysaccharide biosynthetic process
C6W76_RS26380	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
C6W76_RS26385	COG0795	lipopolysaccharide-transporting ATPase activity
C6W76_RS26400	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C6W76_RS26410	COG0318	PFAM AMP-dependent synthetase and ligase
C6W76_RS26420	COG0456	acetyltransferase
C6W76_RS26425	COG2186	Transcriptional regulator
C6W76_RS26430	COG0277	FAD linked oxidase domain protein
C6W76_RS26435	COG0277	FAD linked oxidase domain protein
C6W76_RS26440	COG0247	lactate metabolic process
C6W76_RS26445	COG3193	protein, possibly involved in utilization of glycolate and propanediol
C6W76_RS26450	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C6W76_RS26465	COG3064	Membrane
C6W76_RS26490	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C6W76_RS26495	COG1459	type II secretion system
C6W76_RS26500	COG2165	general secretion pathway protein
C6W76_RS26820	COG1811	Na channel or pump
C6W76_RS26830	COG1982	Orn Lys Arg decarboxylase major
C6W76_RS26835	COG2211	Major facilitator Superfamily
C6W76_RS26850	COG1194	a g-specific adenine glycosylase
C6W76_RS26865	COG3171	Protein conserved in bacteria
C6W76_RS26875	COG0252	asparaginase activity
C6W76_RS26890	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
C6W76_RS26895	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C6W76_RS26900	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C6W76_RS26915	COG0762	integral membrane protein
C6W76_RS26920	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C6W76_RS26925	COG2805	Type II/IV secretion system protein
C6W76_RS26940	COG0189	ligase activity
C6W76_RS26945	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C6W76_RS26950	COG2356	endonuclease I
C6W76_RS26960	COG2814	Major facilitator Superfamily
C6W76_RS26985	COG1166	arginine decarboxylase activity
C6W76_RS26995	COG0501	Belongs to the peptidase M48B family
C6W76_RS27000	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C6W76_RS27005	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6W76_RS27010	COG2213	PTS system mannitol-specific
C6W76_RS27015	COG1063	alcohol dehydrogenase
C6W76_RS27020	COG1494	fructose-1,6-bisphosphatase
C6W76_RS27025	COG3722	fumarate hydratase activity
C6W76_RS27030	COG1072	(Pantothenic acid kinase))
C6W76_RS27035	COG1122	ATPase activity
C6W76_RS27040	COG1122	ATPase activity
C6W76_RS27075	COG0191	fructose-bisphosphate aldolase activity
C6W76_RS27085	COG0668	transmembrane transport
C6W76_RS27095	COG2968	Membrane
C6W76_RS27100	COG0583	DNA-binding transcription factor activity
C6W76_RS27105	COG0427	acetyl-CoA hydrolase
C6W76_RS27110	COG1024	Enoyl-CoA hydratase
C6W76_RS27115	COG1703	isobutyryl-CoA mutase activity
C6W76_RS27120	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C6W76_RS27120	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C6W76_RS27140	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C6W76_RS27160	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C6W76_RS27185	COG0006	proline dipeptidase activity
C6W76_RS27190	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C6W76_RS27195	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C6W76_RS27215	COG1028	Short-chain dehydrogenase reductase Sdr
C6W76_RS27220	COG2723	6-phospho-beta-galactosidase activity
C6W76_RS27230	COG1272	protein, Hemolysin III
C6W76_RS27240	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
C6W76_RS27250	COG0716	FMN binding
C6W76_RS27255	COG4974	Belongs to the 'phage' integrase family
C6W76_RS27260	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C6W76_RS27290	COG2233	PERMEase
C6W76_RS27300	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6W76_RS27300	COG0493	'glutamate synthase
C6W76_RS27305	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6W76_RS27310	COG2252	PERMEase
C6W76_RS27320	COG2233	PERMEase
C6W76_RS27325	COG2080	2 iron, 2 sulfur cluster binding
C6W76_RS27325	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C6W76_RS27330	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C6W76_RS27335	COG0402	S-adenosylhomocysteine deaminase activity
C6W76_RS27340	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6W76_RS27340	COG0493	'glutamate synthase
C6W76_RS27345	COG2068	MobA-Related Protein
C6W76_RS27350	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C6W76_RS27355	COG3608	succinylglutamate desuccinylase aspartoacylase
C6W76_RS27355	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C6W76_RS27360	COG0549	Belongs to the carbamate kinase family
C6W76_RS27370	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C6W76_RS27375	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C6W76_RS27380	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C6W76_RS27385	COG3829	transcription factor binding
C6W76_RS27390	COG2080	2 iron, 2 sulfur cluster binding
C6W76_RS27395	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C6W76_RS27410	COG4942	peptidase
C6W76_RS27465	COG3710	Transcriptional regulator
C6W76_RS27470	COG2771	luxR family
C6W76_RS27475	COG0814	amino acid
C6W76_RS27480	COG0183	Belongs to the thiolase family
C6W76_RS27490	COG1028	Short-chain dehydrogenase reductase Sdr
C6W76_RS27495	COG2814	Major facilitator Superfamily
C6W76_RS27500	COG1794	racemase activity, acting on amino acids and derivatives
C6W76_RS27505	COG0583	DNA-binding transcription factor activity
C6W76_RS27515	COG1609	Transcriptional regulator
C6W76_RS27530	COG0667	Aldo Keto reductase
C6W76_RS27540	COG0861	Integral membrane protein TerC family
C6W76_RS27555	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
C6W76_RS27570	COG2165	general secretion pathway protein
C6W76_RS27575	COG4795	General secretion pathway protein
C6W76_RS27585	COG4967	type IV pilus modification protein PilV
C6W76_RS27590	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
C6W76_RS27600	COG1074	ATP-dependent DNA helicase activity
C6W76_RS27605	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C6W76_RS27610	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C6W76_RS27610	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C6W76_RS27620	COG0860	N-Acetylmuramoyl-L-alanine amidase
C6W76_RS27640	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
C6W76_RS27645	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C6W76_RS27650	COG2166	iron-sulfur cluster assembly
C6W76_RS27655	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C6W76_RS27665	COG0583	DNA-binding transcription factor activity
C6W76_RS27670	COG2363	Small membrane protein
C6W76_RS27680	COG1349	DNA-binding transcription factor activity
C6W76_RS27700	COG0738	Major facilitator superfamily
C6W76_RS27705	COG0235	Class ii aldolase
C6W76_RS27710	COG1454	alcohol dehydrogenase
C6W76_RS27720	COG1760	l-serine dehydratase
C6W76_RS27725	COG0814	amino acid
C6W76_RS27730	COG1611	Belongs to the LOG family
C6W76_RS27745	COG3098	single-species biofilm formation
C6W76_RS27750	COG0564	pseudouridine synthase activity
C6W76_RS27755	COG0716	FMN binding
C6W76_RS27760	COG2271	Major facilitator Superfamily
C6W76_RS27770	COG4948	Mandelate Racemase Muconate Lactonizing
C6W76_RS27775	COG3850	Histidine kinase
C6W76_RS27775	COG4999	Histidine kinase
C6W76_RS27775	COG2205	protein histidine kinase activity
C6W76_RS27775	COG3437	response regulator, receiver
C6W76_RS27785	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C6W76_RS27790	COG2336	PFAM SpoVT AbrB
C6W76_RS27795	COG2337	Toxic component of a toxin-antitoxin (TA) module
C6W76_RS27800	COG3956	TIGRFAM MazG family protein
C6W76_RS27825	COG0602	queuosine metabolic process
C6W76_RS27835	COG2223	nitrite transmembrane transporter activity
C6W76_RS27845	COG0277	FAD linked oxidase domain protein
C6W76_RS27850	COG0477	Major facilitator Superfamily
C6W76_RS27855	COG2086	electron transfer activity
C6W76_RS27860	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C6W76_RS27865	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
C6W76_RS27870	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C6W76_RS27880	COG0720	synthase
C6W76_RS27935	COG1857	crispr-associated protein
C6W76_RS27955	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6W76_RS27960	COG2234	aminopeptidase activity
C6W76_RS28015	COG1388	LysM domain
C6W76_RS28015	COG4942	peptidase
C6W76_RS28020	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C6W76_RS28045	COG2610	gluconate transmembrane transporter activity
C6W76_RS28050	COG3622	Belongs to the hyi family
C6W76_RS28055	COG0235	Class ii aldolase
C6W76_RS28070	COG1349	DNA-binding transcription factor activity
C6W76_RS28075	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C6W76_RS28100	COG0309	Hydrogenase expression formation protein (HypE)
C6W76_RS28105	COG0409	Hydrogenase expression formation protein
C6W76_RS28110	COG0298	carbon dioxide binding
C6W76_RS28115	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
C6W76_RS28120	COG0375	protein maturation
C6W76_RS28130	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6W76_RS28135	COG0651	ATP synthesis coupled electron transport
C6W76_RS28140	COG0650	Formate hydrogenlyase subunit 4
C6W76_RS28145	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
C6W76_RS28145	COG3261	NADH dehydrogenase
C6W76_RS28150	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C6W76_RS28155	COG3260	NADH ubiquinone oxidoreductase 20
C6W76_RS28165	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C6W76_RS28175	COG4680	protein conserved in bacteria
C6W76_RS28180	COG5499	transcription regulator containing HTH domain
C6W76_RS28185	COG2723	6-phospho-beta-galactosidase activity
C6W76_RS28335	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
C6W76_RS28435	COG3468	outer membrane autotransporter barrel domain protein
C6W76_RS28505	COG0726	polysaccharide deacetylase
C6W76_RS28510	COG0297	glycogen (starch) synthase activity
C6W76_RS28515	COG2194	sulfuric ester hydrolase activity
C6W76_RS28520	COG1560	Kdo2-lipid A biosynthetic process
C6W76_RS28555	COG2274	protein secretion by the type I secretion system