locus-tag class description HUU83_RS00010 ENOG4105VZ1 Replication Protein HUU83_RS00020 ENOG4105ED4 portal protein HUU83_RS00110 ENOG4105PTU response to oxidative stress HUU83_RS00115 ENOG4108US3 tail fiber assembly HUU83_RS00125 ENOG4108C33 Resolvase HUU83_RS00165 ENOG4105ZTC transcriptional activator, Ogr delta HUU83_RS00190 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein HUU83_RS00205 ENOG4105EBK exported protein HUU83_RS00210 ENOG4108VTS Membrane HUU83_RS00215 ENOG41065TG regulatoR HUU83_RS00225 ENOG4105DP0 ferredoxin-NADP reductase HUU83_RS00230 ENOG4105CBT Fructose-1,6-bisphosphatase HUU83_RS00240 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) HUU83_RS00255 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase HUU83_RS00270 ENOG41063M6 Cell Division Protein HUU83_RS00275 ENOG4105ETE Transcriptional regulator (LacI family HUU83_RS00280 ENOG4105C25 Primosomal protein n' HUU83_RS00305 ENOG4107S01 Repressor protein MetJ HUU83_RS00315 ENOG4105C28 cystathionine HUU83_RS00320 ENOG4105CFH Aspartokinase HUU83_RS00325 ENOG4105SYT Methylenetetrahydrofolate reductase HUU83_RS00335 ENOG4108Q5Y Membrane HUU83_RS00340 ENOG4108XC3 NADH ubiquinone oxidoreductase HUU83_RS00345 ENOG4105DCT glycerol dehydrogenase HUU83_RS00350 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) HUU83_RS00355 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) HUU83_RS00360 ENOG4105DM4 PTS System HUU83_RS00365 ENOG4108YRF PTS System HUU83_RS00375 ENOG4108AHH pyruvate formate lyase II activase HUU83_RS00380 ENOG4108XCZ PTS System HUU83_RS00385 ENOG4106R3P AraC family transcriptional regulator HUU83_RS00390 ENOG4105DIJ Phosphoethanolamine transferase HUU83_RS00400 ENOG4105CWC Acetylornithine deacetylase HUU83_RS00405 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase HUU83_RS00420 ENOG4105C5Q Transcriptional regulator HUU83_RS00430 ENOG4105EJ2 Transcriptional regulator HUU83_RS00435 ENOG4108Y73 Membrane HUU83_RS00480 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase HUU83_RS00515 ENOG4105PM1 preprotein translocase subunit SecE HUU83_RS00520 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) HUU83_RS00555 ENOG410645W Thiamin biosynthesis protein ThiH HUU83_RS00560 ENOG4105D41 biosynthesis protein thiH HUU83_RS00570 ENOG4105WHD thiamine biosynthesis protein ThiS HUU83_RS00575 ENOG4105D06 uba thif-type nad fad binding protein HUU83_RS00610 ENOG4105R2J Conserved Protein HUU83_RS00620 ENOG4108T8B Protein of unknown function (DUF1481) HUU83_RS00625 ENOG4105JBU Binds zinc. Could be an important component of the zinc- balancing mechanism HUU83_RS00630 ENOG4105BZU Histidine kinase HUU83_RS00635 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HUU83_RS00640 ENOG4105C12 Phosphoribosylglycinamide synthetase HUU83_RS00670 ENOG4105K5X acetyltransferase HUU83_RS00680 ENOG4107QP3 malate synthase g HUU83_RS00685 ENOG4108I9X Isocitrate lyase HUU83_RS00700 ENOG41069M3 Transcriptional regulator HUU83_RS00705 ENOG4105C3R Methionine synthase HUU83_RS00710 ENOG4105EAM Na Pi-cotransporter HUU83_RS00720 ENOG4105FE9 pseudouridine synthase HUU83_RS00725 ENOG4108ZR5 Conserved Protein HUU83_RS00735 ENOG410756H nucleotidyltransferase HUU83_RS00740 ENOG4108WZA zeta toxin HUU83_RS00745 ENOG4105CFH Aspartokinase HUU83_RS00760 ENOG4108MDC (LipO)protein HUU83_RS00765 ENOG4108Q9C Periplasmic Protein HUU83_RS00770 ENOG4105E3R (LipO)protein HUU83_RS00785 ENOG4107QNK )-transporter HUU83_RS00790 ENOG4105EG2 ABC transporter, permease HUU83_RS00795 ENOG4105D56 permease protein HUU83_RS00800 ENOG4107FKK extracellular solute-binding protein family 1 HUU83_RS00805 ENOG4108IJ9 (ABC) transporter HUU83_RS00815 ENOG4107W52 maltose operon periplasmic protein HUU83_RS00840 ENOG41080IJ Diacylglycerol kinase HUU83_RS00850 ENOG4107R73 Mate efflux family protein HUU83_RS00855 ENOG4105VDW Csbd family HUU83_RS00860 ENOG4105MYN Zinc uptake regulation protein HUU83_RS00870 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) HUU83_RS00875 ENOG4105P4Z Phage shock protein G HUU83_RS00880 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein HUU83_RS00885 ENOG4105CDU Replicative dna helicase HUU83_RS00890 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) HUU83_RS00895 ENOG4105CGF Aromatic amino acid aminotransferase HUU83_RS00905 ENOG4105F0S class B acid phosphatase HUU83_RS00910 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme HUU83_RS00915 ENOG4105MSB protein, conserved in bacteria HUU83_RS00920 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) HUU83_RS00925 ENOG4108UUM single-stranded DNA-binding protein HUU83_RS00930 ENOG4105PMV Membrane HUU83_RS00935 ENOG4108M8H domain protein HUU83_RS00940 ENOG4108W3Q Transcriptional regulator HUU83_RS00945 ENOG4108Z4X TRANSCRIPTIONal HUU83_RS00950 ENOG4105C7N Xanthine uracil vitamin C permease HUU83_RS00955 ENOG4105EEQ Na H antiporter HUU83_RS00970 ENOG41062QD Membrane HUU83_RS00985 ENOG4105JJ8 Cytochrome c nitrite reductase, pentaheme subunit HUU83_RS00990 ENOG4105D3S 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HUU83_RS00995 ENOG4105DVI reductase, NrfD HUU83_RS01000 ENOG4108QKW cytochrome c-type biogenesis protein HUU83_RS01010 ENOG4108W0S formate-dependent nitrite reductase complex HUU83_RS01015 ENOG4105CK2 sodium dicarboxylate symporter HUU83_RS01020 ENOG41082ND Uncharacterized protein yjcO HUU83_RS01030 ENOG4105ETP RND efflux system, outer membrane lipoprotein HUU83_RS01035 ENOG4108MI0 Resistance protein HUU83_RS01040 ENOG4105J12 Multidrug resistance protein mdtN HUU83_RS01050 ENOG4105EUZ Beta-lactamase domain protein HUU83_RS01055 ENOG4108YZG isomerase HUU83_RS01065 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein HUU83_RS01070 ENOG410849A acetyltransferase, (GNAT) family HUU83_RS01075 ENOG4105MFQ Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity) HUU83_RS01080 ENOG4105FD8 phosphonate metabolism protein PhnM HUU83_RS01085 ENOG4105HRV phosphonate c-p lyase system protein phnl HUU83_RS01090 ENOG4105ENV phosphonate C-P lyase system protein PhnK HUU83_RS01095 ENOG4105FT8 Phosphonate metabolism HUU83_RS01100 ENOG4105EKV Phosphonate metabolism protein HUU83_RS01105 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH HUU83_RS01110 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG HUU83_RS01115 ENOG4107RJJ Transcriptional regulator HUU83_RS01125 ENOG4105EHI Phosphonate ABC transporter, periplasmic HUU83_RS01130 ENOG4105D5T phosphonate abc transporter HUU83_RS01135 ENOG4108SQ4 Glyoxalase Bleomycin resistance protein (Dioxygenase HUU83_RS01140 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA HUU83_RS01145 ENOG4108F5E vimentin HUU83_RS01150 ENOG4108YIV HUU83_RS01155 ENOG4105CSH Transporter HUU83_RS01165 ENOG4105ECM Sensor protein basS pmrB HUU83_RS01170 ENOG4105XJC Two component transcriptional regulator (Winged helix family HUU83_RS01175 ENOG4105DIJ Phosphoethanolamine transferase HUU83_RS01180 ENOG4105D5Q Arginine ornithine antiporter HUU83_RS01185 ENOG4106ZGR Transcriptional regulator HUU83_RS01190 ENOG4105CXN decarboxylase HUU83_RS01195 ENOG4108K2B transcriptional regulator HUU83_RS01200 ENOG4105F8D glycoside hydrolase family 4 HUU83_RS01205 ENOG4105CT4 transporter HUU83_RS01210 ENOG4108R5S membrane HUU83_RS01215 ENOG4107GFK fumarate HUU83_RS01220 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter HUU83_RS01225 ENOG4108MRH transcriptional regulatory protein HUU83_RS01230 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism HUU83_RS01235 ENOG4105VR1 Pfam:DUF1271 HUU83_RS01240 ENOG410830R acetyltransferase HUU83_RS01255 ENOG4105CRK lysyL-tRNA synthetase HUU83_RS01260 ENOG4105DUX Transporter HUU83_RS01265 ENOG4105CXN decarboxylase HUU83_RS01270 ENOG4105D5Q Arginine ornithine antiporter HUU83_RS01275 ENOG4108M3R transcriptional activator CadC HUU83_RS01285 ENOG4108SIC Transcriptional regulator HUU83_RS01300 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter HUU83_RS01305 ENOG4108IJ0 Aspartate ammonia-lyase HUU83_RS01310 ENOG4108YH1 overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7 HUU83_RS01315 ENOG4105DVH amino acid HUU83_RS01330 ENOG4108ZVF (LipO)protein HUU83_RS01335 ENOG4105MTB Uncharacterized protein YjeJ HUU83_RS01340 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein HUU83_RS01350 ENOG4107PEH Entericidin EcnA/B family HUU83_RS01355 ENOG4106BSU Entericidin B HUU83_RS01360 ENOG4105KPY Small multidrug resistance protein HUU83_RS01365 ENOG4105QNF Outer membrane lipoprotein HUU83_RS01370 ENOG41066YJ Beta-lactamase HUU83_RS01385 ENOG4105E33 succinate dehydrogenase HUU83_RS01390 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) HUU83_RS01400 ENOG4107SC7 Inner membrane transporter yjeM HUU83_RS01405 ENOG4105EGS Mechanosensitive ion channel HUU83_RS01445 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) HUU83_RS01450 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) HUU83_RS01455 ENOG4105K8N protein family UPF0079, ATPase HUU83_RS01460 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase HUU83_RS01480 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) HUU83_RS01485 ENOG4107QJR hflk protein HUU83_RS01490 ENOG4105EPW hflc protein HUU83_RS01510 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) HUU83_RS01515 ENOG4105C2N RNA methyltransferase TrmH family group 3 HUU83_RS01520 ENOG4105FUX Conserved Protein HUU83_RS01525 ENOG4108P9J Phage shock protein A HUU83_RS01530 ENOG4107VNS Protein of unknown function (DUF2491) HUU83_RS01535 ENOG4105Z6B inner membrane protein yjfl HUU83_RS01540 ENOG4108KXT Conserved Protein HUU83_RS01545 ENOG4106032 Glutathionylspermidine synthase HUU83_RS01550 ENOG4105CSU acyl-Coa dehydrogenase HUU83_RS01555 ENOG4105S17 UPF0379 protein yjfN HUU83_RS01560 ENOG4105WSB biofilm stress and motility protein A HUU83_RS01565 ENOG4108MXZ Esterase HUU83_RS01580 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC HUU83_RS01595 ENOG4105H6Q decarboxylase HUU83_RS01610 ENOG4105R3P Inner membrane protein yagU HUU83_RS01615 ENOG4105KIT UPF0379 protein yjfY HUU83_RS01630 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) HUU83_RS01640 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit HUU83_RS01645 ENOG4105CG6 trap dicarboxylate transporter dctm subunit HUU83_RS01650 ENOG41069H7 transport system small permease component HUU83_RS01655 ENOG4107S3R L-aspartate oxidase HUU83_RS01660 ENOG4107R0K CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) HUU83_RS01665 ENOG4105E39 Enoyl-CoA hydratase HUU83_RS01675 ENOG4105CHR reductase HUU83_RS01685 ENOG4105FHY Opacity-associated protein A HUU83_RS01690 ENOG4108V1T peptidylprolyl cis-trans isomerase HUU83_RS01695 ENOG4105C85 amino acid HUU83_RS01705 ENOG4105DXC membrane HUU83_RS01710 ENOG4105ECR NmrA family HUU83_RS01715 ENOG4105KVH Transcriptional regulator HUU83_RS01720 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic HUU83_RS01725 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase HUU83_RS01730 ENOG4108UUE Transcriptional regulator HUU83_RS01735 ENOG41061GZ Protein of unknown function (DUF1107) HUU83_RS01740 ENOG4105C37 (CBS) domain HUU83_RS01750 ENOG4105CFU surface antigen HUU83_RS01755 ENOG4105MA0 exported protein HUU83_RS01760 ENOG4108ZHD aig2 family HUU83_RS01765 ENOG4105F0N pyrophosphate phospho-hydrolase HUU83_RS01770 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator HUU83_RS01775 ENOG4105C2J ABC transporter HUU83_RS01780 ENOG4107R9N ABC transporter HUU83_RS01785 ENOG41062B0 ABC transporter, permease HUU83_RS01795 ENOG4105DFU Cell wall formation (By similarity) HUU83_RS01805 ENOG4105CMS peptidase U62, modulator of DNA gyrase HUU83_RS01815 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) HUU83_RS01820 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase HUU83_RS01825 ENOG4105CG3 alpha amylase, catalytic region HUU83_RS01830 ENOG4105C5Y PTS System HUU83_RS01835 ENOG4105D4X repressor HUU83_RS01845 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic HUU83_RS01855 ENOG4105KME endoribonuclease L-psp HUU83_RS01870 ENOG4107C93 pyrBI operon leader peptide HUU83_RS01875 ENOG4108UQ8 endoribonuclease L-psp HUU83_RS01880 ENOG4105F6U Short-chain dehydrogenase reductase Sdr HUU83_RS01885 ENOG4108XFH Transcriptional regulator HUU83_RS01890 ENOG4105XEP YhcH YjgK YiaL family protein HUU83_RS01905 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) HUU83_RS01910 ENOG4108MJ3 acetyltransferase HUU83_RS01915 ENOG4108M3P Membrane HUU83_RS01920 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) HUU83_RS01925 ENOG4105MYG DNA polymerase iii, chi subunit HUU83_RS01935 ENOG4108M8S permease YjgP YjgQ family protein HUU83_RS01940 ENOG4108K5H permease YjgP YjgQ family protein HUU83_RS01945 ENOG4105D7A ATP-binding protein HUU83_RS01950 ENOG4105DQ4 alcohol dehydrogenase HUU83_RS01970 ENOG4108UMW Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) HUU83_RS01995 ENOG4105C0D helicase HUU83_RS02060 ENOG4108W9T type 1 fimbriae regulatory protein HUU83_RS02065 ENOG4105E71 FimE is one of the 2 regulatory proteins which control the phase variation of type 1 fimbriae in E.coli. These proteins mediate the periodic inversion of a 300bp DNA segment that harbors the promoter for the fimbrial structural gene, fimA. FimE switches fimA off HUU83_RS02070 ENOG4108RQP Major type 1 subunit fimbrin HUU83_RS02075 ENOG4108S54 Fimbrial protein HUU83_RS02080 ENOG4108NAE Fimbrial chaperone protein HUU83_RS02085 ENOG4105CW0 outer membrane usher protein HUU83_RS02090 ENOG4108SQA Fimbrial HUU83_RS02095 ENOG4108T65 Fimbrial HUU83_RS02100 ENOG410643X FIMH SUBUNIT MANNOSE-sensitive type 1 fimbrial adhesin HUU83_RS02105 ENOG4107EFN gluconate transport system permease 3 HUU83_RS02115 ENOG4105DEI Mannitol dehydrogenase HUU83_RS02120 ENOG4105C6F GntR Family Transcriptional Regulator HUU83_RS02140 ENOG4107YNJ LysR family Transcriptional regulator HUU83_RS02145 ENOG4105DYB Isoaspartyl dipeptidase HUU83_RS02150 ENOG4108P2H Inner membrane protein YjiG HUU83_RS02155 ENOG41074DU domain protein HUU83_RS02165 ENOG4105CBP Major Facilitator HUU83_RS02180 ENOG4105CIZ coA-substrate-specific enzyme activase HUU83_RS02185 ENOG4105DCU 2-hydroxyglutaryl-CoA dehydratase HUU83_RS02190 ENOG4106BRA Membrane HUU83_RS02195 ENOG41083G8 Multidrug resistance protein MdtM HUU83_RS02210 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family HUU83_RS02215 ENOG4106DIZ Domain of unknown function (DUF1127) HUU83_RS02235 ENOG4107QTH restriction modification system DNA specificity domain HUU83_RS02245 ENOG4108F3G Type I restriction-modification system, R subunit HUU83_RS02260 ENOG4105CKI cobalamin synthesis protein HUU83_RS02265 ENOG4105VCD cytoplasmic protein HUU83_RS02270 ENOG4105D22 carbon starvation protein HUU83_RS02275 ENOG4107UWN reductase HUU83_RS02280 ENOG4105EFA 4-hydroxyphenylacetate HUU83_RS02310 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase HUU83_RS02315 ENOG4105C26 Dehydrogenase HUU83_RS02320 ENOG4105ERH Fumarylacetoacetate hydrolase HUU83_RS02325 ENOG4108V8F Transcriptional regulator, MarR family HUU83_RS02330 ENOG4105C8Q Methyl-accepting chemotaxis HUU83_RS02335 ENOG4108I5G Major Facilitator superfamily HUU83_RS02340 ENOG410617M Transcriptional regulator HUU83_RS02345 ENOG4105CPQ Dehydrogenase HUU83_RS02355 ENOG4105RI1 glycoprotein receptor HUU83_RS02360 ENOG4106CVF DNA replication protein HUU83_RS02375 ENOG4105DWK Membrane HUU83_RS02380 ENOG4108N8T regulatoR HUU83_RS02385 ENOG4108T94 DNA-binding transcriptional activator BglJ HUU83_RS02390 ENOG4108819 ferric iron reductase HUU83_RS02395 ENOG4105YBH Protein of unknown function (DUF1435) HUU83_RS02420 ENOG4108WPU DNA polymerase III subunit psi HUU83_RS02425 ENOG4105KEG ribosomal-protein-alanine acetyltransferase HUU83_RS02430 ENOG4105PAD Hydrolase HUU83_RS02455 ENOG4108R7K Metal Dependent Phosphohydrolase HUU83_RS02460 ENOG4108HJ1 Uncharacterized conserved protein (DUF2303) HUU83_RS02465 ENOG4105H40 HUU83_RS02480 ENOG4108S1U HUU83_RS02485 ENOG4106050 phage regulatory protein, rha family HUU83_RS02515 ENOG4106CZA Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC (By similarity) HUU83_RS02525 ENOG4108MXB Protein of unknown function (DUF968) HUU83_RS02530 ENOG4105HRS Antitermination protein HUU83_RS02550 ENOG4105QFS Lysis protein S homolog from lambdoid prophage HUU83_RS02555 ENOG4105KUS lysozyme HUU83_RS02590 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) HUU83_RS02665 ENOG4108X9F tail fiber protein HUU83_RS02670 ENOG4105UZW Tail fiber assembly protein HUU83_RS02685 ENOG4105Y50 Virulence Protein HUU83_RS02700 ENOG4106FE3 DNA repair HUU83_RS02710 ENOG4105K3G Periplasmic Protein HUU83_RS02720 ENOG4108NRW Phospholipase, patatin family HUU83_RS02725 ENOG4105EYA deoxyribonuclease HUU83_RS02730 ENOG41076CZ activating enzyme HUU83_RS02735 ENOG4105G0K glycine radical enzyme YjjI family HUU83_RS02770 ENOG41062Z9 Membrane HUU83_RS02775 ENOG4105EAC phosphoserine phosphatase HUU83_RS02780 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) HUU83_RS02785 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase HUU83_RS02790 ENOG4105C5H ABC transporter HUU83_RS02795 ENOG4107SC1 transglycosylase HUU83_RS02810 ENOG4108K16 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) HUU83_RS02820 ENOG4105UEI Transcriptional Regulator AraC Family HUU83_RS02825 ENOG4108RH0 Crea protein HUU83_RS02830 ENOG4105E3W Two component transcriptional regulator (Winged helix family HUU83_RS02835 ENOG4105EB3 Histidine kinase HUU83_RS02840 ENOG4105CT7 inner membrane cred family protein HUU83_RS02845 ENOG41065U4 response regulator HUU83_RS02850 ENOG410759A HUU83_RS02855 ENOG4106FVC RNA methyltransferase HUU83_RS02865 ENOG4105CFH Aspartokinase HUU83_RS02875 ENOG4105D98 threonine synthase HUU83_RS02880 ENOG41062C6 Protein of unknown function (DUF2502) HUU83_RS02895 ENOG4105BZG amino acid carrier protein HUU83_RS02905 ENOG4108RIR Molybdenum cofactor biosynthesis protein HUU83_RS02910 ENOG4106HK8 GPR1 FUN34 yaaH family protein HUU83_RS02915 ENOG4108QUJ UPF0174 protein YaaW HUU83_RS02935 ENOG4105WI6 cell killing protein encoded within cryptic prophage HUU83_RS02945 ENOG41063Z6 transcriptional regulator, lysR family HUU83_RS02970 ENOG410647N response to DNA damage stimulus HUU83_RS02975 ENOG4105DTN riboflavin biosynthesis protein ribF HUU83_RS02980 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) HUU83_RS02990 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase HUU83_RS03010 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain HUU83_RS03015 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain HUU83_RS03020 ENOG4108XNW Transcriptional activatory protein CaiF HUU83_RS03030 ENOG4106YT9 Enoyl-CoA hydratase HUU83_RS03065 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase HUU83_RS03070 ENOG4105IBM Could be part of an electron transfer system required for anaerobic carnitine reduction. Could be a 3Fe-4S cluster- containing protein HUU83_RS03075 ENOG4105C54 Major Facilitator superfamily HUU83_RS03090 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) HUU83_RS03115 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) HUU83_RS03120 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) HUU83_RS03125 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) HUU83_RS03130 ENOG4105D3G Pseudouridine synthase HUU83_RS03140 ENOG4105CQ2 DNA polymerase HUU83_RS03145 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase HUU83_RS03160 ENOG41063TF transcriptional regulator (AraC HUU83_RS03165 ENOG4108KF1 Membrane HUU83_RS03175 ENOG4106SMU thiamine transporter membrane protein HUU83_RS03180 ENOG4105DP9 ABC transporter HUU83_RS03195 ENOG4105S8Q sugar efflux transporter HUU83_RS03210 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) HUU83_RS03225 ENOG41064T2 transcriptional regulator, lysR family HUU83_RS03235 ENOG4105C7K acetolactate synthase HUU83_RS03240 ENOG4108ZP8 Acetolactate synthase small subunit HUU83_RS03250 ENOG4107B7Y DNA-binding transcriptional regulator FruR HUU83_RS03265 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) HUU83_RS03270 ENOG4105CJN penicillin-binding protein HUU83_RS03275 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) HUU83_RS03280 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) HUU83_RS03295 ENOG4105CNI cell division protein FtsW HUU83_RS03310 ENOG4105CPF Cell wall formation (By similarity) HUU83_RS03315 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) HUU83_RS03320 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) HUU83_RS03325 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) HUU83_RS03335 ENOG4108SR7 Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation (By similarity) HUU83_RS03345 ENOG4105M6F mutator MutT protein HUU83_RS03360 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) HUU83_RS03375 ENOG4105D7Q type ii secretion system HUU83_RS03380 ENOG4107QHF type ii secretion system protein e HUU83_RS03385 ENOG4108ZUW Major pilin subunit HUU83_RS03390 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase HUU83_RS03395 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase HUU83_RS03400 ENOG4106A72 regulatory protein AmpE HUU83_RS03405 ENOG4105C85 amino acid HUU83_RS03410 ENOG41073TP transcriptional regulator HUU83_RS03415 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) HUU83_RS03420 ENOG4107QSN dihydrolipoamide acetyltransferase HUU83_RS03425 ENOG4107QN2 dihydrolipoyl dehydrogenase HUU83_RS03430 ENOG4108NST exported protein HUU83_RS03435 ENOG4107QIJ Aconitate hydratase 2 HUU83_RS03455 ENOG4108ZRK uncharacterized protein yacC HUU83_RS03460 ENOG4105E3B Multicopper oxidase HUU83_RS03465 ENOG4105DZG Dehydrogenase HUU83_RS03470 ENOG4108UGV hypoxanthine phosphoribosyltransferase HUU83_RS03475 ENOG41077A9 carbonic anhydrase HUU83_RS03480 ENOG4105DA5 (ABC) transporter HUU83_RS03485 ENOG4105E3A (ABC) transporter HUU83_RS03490 ENOG4108YTN IIa component HUU83_RS03495 ENOG4107BJW polysaccharide deacetylase HUU83_RS03505 ENOG4108A32 Transposase HUU83_RS03520 ENOG4105P0Q fimbrial-like protein YadC HUU83_RS03525 ENOG4105SN2 fimbrial-like adhesin protein HUU83_RS03530 ENOG4105SYG Fimbrial protein HUU83_RS03535 ENOG4108XEY fimbrial-like adhesin protein HUU83_RS03540 ENOG4105CW0 outer membrane usher protein HUU83_RS03545 ENOG4108VEV chaperone HUU83_RS03555 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase HUU83_RS03560 ENOG4105DJ0 Poly(A) Polymerase HUU83_RS03580 ENOG4107XID 2'-5' rna ligase HUU83_RS03585 ENOG4105CQ7 ATP-dependent helicase HUU83_RS03590 ENOG4105BZ4 penicillin-binding protein HUU83_RS03595 ENOG4105E0K tonB-dependent siderophore receptor HUU83_RS03600 ENOG4105E0A ABC, transporter HUU83_RS03605 ENOG4105J76 Periplasmic binding protein HUU83_RS03610 ENOG4105S6R Iron-hydroxamate transporter permease subunit HUU83_RS03635 ENOG4105EN6 Membrane HUU83_RS03640 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) HUU83_RS03655 ENOG4105C0H protease HUU83_RS03660 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR HUU83_RS03680 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) HUU83_RS03705 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) HUU83_RS03710 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) HUU83_RS03715 ENOG4105KNE Phosphatidate cytidylyltransferase HUU83_RS03720 ENOG4105DZP Membrane-associated zinc metalloprotease HUU83_RS03730 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) HUU83_RS03735 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) HUU83_RS03760 ENOG4105C0B DNA polymerase III (alpha subunit) HUU83_RS03770 ENOG4105CXN decarboxylase HUU83_RS03775 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase HUU83_RS03780 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) HUU83_RS03785 ENOG4105M1T rho-binding antiterminator HUU83_RS03795 ENOG4108VWS Yaeq family HUU83_RS03800 ENOG4108YZN class I peptide chain release factor HUU83_RS03805 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion HUU83_RS03825 ENOG4108R96 Methyltransferase, YaeB family HUU83_RS03830 ENOG4108R8X outer membrane lipoprotein HUU83_RS03835 ENOG4105D01 (LipO)protein HUU83_RS03840 ENOG4108UMI ABC transporter, permease HUU83_RS03845 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) HUU83_RS03850 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase HUU83_RS03885 ENOG4105CV8 reductase HUU83_RS03890 ENOG4105HEI LysR family (Transcriptional regulator HUU83_RS03900 ENOG4105F2W methyltransferase HUU83_RS03905 ENOG4105E9H Lytic Murein transglycosylase HUU83_RS03910 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) HUU83_RS03915 ENOG4105D1A Methyltransferase HUU83_RS03925 ENOG4107RZZ dna polymerase iii epsilon subunit HUU83_RS03935 ENOG410600K aminopeptidase HUU83_RS03950 ENOG4105GMB type VI secretion system effector, hcp1 family HUU83_RS03980 ENOG410600T transposase HUU83_RS03985 ENOG4105CNA YD repeat protein HUU83_RS03990 ENOG4107TV1 YD repeat protein HUU83_RS04015 ENOG4105CZ7 nitrilase cyanide hydratase and apolipoprotein n-acyltransferase HUU83_RS04020 ENOG4108WN0 inhibitor of vertebrate lysozyme HUU83_RS04025 ENOG4107QPN acyl-Coa dehydrogenase HUU83_RS04035 ENOG4105E7A Glutamine amidotransferase HUU83_RS04040 ENOG4105F7V ErfK ybiS ycfS ynhG family protein HUU83_RS04045 ENOG4105VXN addiction module toxin, RelE StbE family HUU83_RS04055 ENOG4108YS0 lipoprotein YafL HUU83_RS04085 ENOG4108HYG acetyltransferase HUU83_RS04095 ENOG4108S2Y peptide Chain Release factor HUU83_RS04100 ENOG4105CIN aminoacyl-histidine dipeptidase HUU83_RS04120 ENOG4105FCK Membrane HUU83_RS04140 ENOG4105DFP Integrase HUU83_RS04155 ENOG4105XB7 anti-repressor protein HUU83_RS04190 ENOG41073DY may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity) HUU83_RS04230 ENOG4107XAN XdhC and CoxI family HUU83_RS04235 ENOG4105C7W Xanthine dehydrogenase HUU83_RS04240 ENOG4105DIP Molybdopterin dehydrogenase FAD-binding HUU83_RS04245 ENOG4107XKX isoquinoline 1-oxidoreductase, alpha subunit HUU83_RS04250 ENOG4105R3P Inner membrane protein yagU HUU83_RS04255 ENOG4105PI0 Ferredoxin HUU83_RS04260 ENOG4108UD7 cell wall organization HUU83_RS04265 ENOG4106PYX Receptor HUU83_RS04270 ENOG4108N3D putative enzyme HUU83_RS04325 ENOG4108KBJ Inner membrane protein YkgB HUU83_RS04330 ENOG41066GK UPF0379 protein ykgI HUU83_RS04335 ENOG4107QN2 dihydrolipoyl dehydrogenase HUU83_RS04340 ENOG4108K01 transcriptional regulator HUU83_RS04345 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) HUU83_RS04350 ENOG4107QR9 Iron-sulfur cluster binding protein HUU83_RS04355 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) HUU83_RS04385 ENOG4105BZU Histidine kinase HUU83_RS04390 ENOG4108W9T type 1 fimbriae regulatory protein HUU83_RS04415 ENOG4105C94 Transporter HUU83_RS04425 ENOG4105BZU Histidine kinase HUU83_RS04430 ENOG4108NUU Transcriptional regulator HUU83_RS04435 ENOG4105SZ2 membrAne HUU83_RS04440 ENOG4107SNB ankyrin repeat protein YahD HUU83_RS04445 ENOG4105N16 Protein of unknown function (DUF2877) HUU83_RS04450 ENOG4107R1Q Membrane protein FdrA HUU83_RS04455 ENOG4107REC cytoplasmic protein HUU83_RS04460 ENOG4105C5B carbamate kinase HUU83_RS04465 ENOG4105DZC cytosine deaminase HUU83_RS04475 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator HUU83_RS04480 ENOG4105C2J ABC transporter HUU83_RS04485 ENOG4105CNN ABC, transporter HUU83_RS04490 ENOG4105CNN ABC, transporter HUU83_RS04495 ENOG4105DQ4 alcohol dehydrogenase HUU83_RS04510 ENOG4105E82 cytochrome subunit of dehydrogenase HUU83_RS04515 ENOG4105TDT uncharacterized protein yahO HUU83_RS04520 ENOG4108JU7 Transcriptional regulator HUU83_RS04525 ENOG4105CR4 methylisocitrate lyase HUU83_RS04530 ENOG4105BZN citrate synthase HUU83_RS04535 ENOG4105DXD 2-methylcitrate dehydratase HUU83_RS04540 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) HUU83_RS04545 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin HUU83_RS04550 ENOG4105DZC cytosine deaminase HUU83_RS04555 ENOG4105DND Transcriptional regulator HUU83_RS04560 ENOG4107B2H carbonic anhydrase HUU83_RS04570 ENOG4105DJ2 Major Facilitator Superfamily HUU83_RS04575 ENOG4108UW5 maltose o-acetyltransferase HUU83_RS04580 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) HUU83_RS04590 ENOG4105ETE Transcriptional regulator (LacI family HUU83_RS04595 ENOG4108K2P TRANSCRIPTIONal HUU83_RS04630 ENOG4108SC4 )-transporter HUU83_RS04635 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme HUU83_RS04655 ENOG4105SRB Uncharacterized protein yaiO HUU83_RS04665 ENOG4108PBI Polysaccharide metabolism HUU83_RS04670 ENOG4107W19 lmbE family HUU83_RS04675 ENOG4106FTQ Taurine ABC transporter, periplasmic HUU83_RS04685 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component HUU83_RS04690 ENOG4105E2B Taurine dioxygenase HUU83_RS04695 ENOG4105D52 delta-aminolevulinic acid dehydratase HUU83_RS04705 ENOG4108PNB DNA-binding transcriptional regulator HUU83_RS04710 ENOG4107R6D beta-lactam binding protein AmpH HUU83_RS04715 ENOG4108DQG in Escherichia coli SbmA is involved in uptake of microcin J25 HUU83_RS04720 ENOG4107QS8 (LipO)protein HUU83_RS04725 ENOG4105FR5 inner membrane protein YaiY HUU83_RS04730 ENOG4105UNH Membrane HUU83_RS04735 ENOG4105CPF Cell wall formation (By similarity) HUU83_RS04750 ENOG4105G6Z alkaline phosphatase HUU83_RS04755 ENOG4105VIF phosphate starvation-inducible protein HUU83_RS04760 ENOG4105BZU Histidine kinase HUU83_RS04765 ENOG4105II7 pyrroline-5-carboxylate reductase HUU83_RS04780 ENOG4105SS3 HUU83_RS04785 ENOG4105HBA AroM protein HUU83_RS04810 ENOG4105DKQ ROK family HUU83_RS04815 ENOG4105F27 Major Facilitator HUU83_RS04820 ENOG4105EYH Exonuclease HUU83_RS04825 ENOG4107RH8 nuclease SbcCD subunit D HUU83_RS04830 ENOG4105CK6 Two component transcriptional regulator (Winged helix family HUU83_RS04835 ENOG4105BZU Histidine kinase HUU83_RS04840 ENOG4105CWM branched-chain amino acid transport system II carrier protein HUU83_RS04845 ENOG4105C85 amino acid HUU83_RS04850 ENOG4107R28 alpha amylase, catalytic region HUU83_RS04870 ENOG4105VIE preprotein translocase, subunit YajC HUU83_RS04875 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) HUU83_RS04880 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) HUU83_RS04885 ENOG4105N1F Hnh endonuclease HUU83_RS04890 ENOG4105DRB nucleoside-specific channel-forming protein HUU83_RS04895 ENOG4108KIC (LipO)protein HUU83_RS04905 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) HUU83_RS04910 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) HUU83_RS04920 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) HUU83_RS04925 ENOG4108ZAI phosphatidylglycerophosphatase a HUU83_RS04930 ENOG4105CPC Aldo Keto reductase HUU83_RS04940 ENOG4105CTB Polyprenyl synthetase HUU83_RS04955 ENOG4107S0N DJ-1 family HUU83_RS04960 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) HUU83_RS04970 ENOG4107RDB Major Facilitator HUU83_RS04995 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) HUU83_RS05000 ENOG4105CCU oxidase (Subunit III) HUU83_RS05005 ENOG4105BZ9 Cytochrome C oxidase, subunit I HUU83_RS05010 ENOG4105E2S oxidase) subunit II HUU83_RS05015 ENOG4105EYM Major Facilitator superfamily HUU83_RS05020 ENOG4105IEY (LipO)protein HUU83_RS05025 ENOG4105M85 Bola protein HUU83_RS05045 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) HUU83_RS05050 ENOG4105K70 DNA-binding protein HUU83_RS05055 ENOG4105EIN peptidylprolyl cis-trans isomerase HUU83_RS05060 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein HUU83_RS05065 ENOG4108TGP Thioesterase superfamily protein HUU83_RS05075 ENOG4108NFA extracellular solute-binding protein HUU83_RS05085 ENOG4108XM1 transcriptional regulator AsnC family HUU83_RS05090 ENOG4105BZ1 (ABC) transporter HUU83_RS05095 ENOG4105BZ1 (ABC) transporter HUU83_RS05100 ENOG4108YZA Nitrogen regulatory protein pii HUU83_RS05105 ENOG4105BZU Histidine kinase HUU83_RS05110 ENOG4105C29 acyl-CoA thioesterase HUU83_RS05115 ENOG4108MNP Glycoprotein polysaccharide metabolism HUU83_RS05120 ENOG41080UX Methyltransferase HUU83_RS05130 ENOG4105KCV RNA signal recognition particle 4.5S RNA HUU83_RS05135 ENOG41066DG (EAL) domain protein HUU83_RS05140 ENOG4105GSJ Inner membrane protein ylaC HUU83_RS05145 ENOG4108UW5 maltose o-acetyltransferase HUU83_RS05150 ENOG4105KF5 hemolysin expression-modulating protein HUU83_RS05155 ENOG4108UKR Biofilm formation regulator YbaJ HUU83_RS05160 ENOG4105BZS acriflavin resistance protein HUU83_RS05165 ENOG4105C1P efflux transporter, rnd family, mfp subunit HUU83_RS05170 ENOG4107XI7 Tetr family transcriptional regulator HUU83_RS05175 ENOG4105EGS Mechanosensitive ion channel HUU83_RS05180 ENOG4106428 Protein of unknown function (DUF2496) HUU83_RS05185 ENOG4108URS primosomal replication protein n'' HUU83_RS05190 ENOG4105WD1 Membrane HUU83_RS05200 ENOG4107QMP dna polymerase iii subunits gamma and tau HUU83_RS05235 ENOG4107RE1 Inosine-guanosine kinase HUU83_RS05240 ENOG4105CKD glutathione-regulated potassium-efflux system protein HUU83_RS05245 ENOG4105EU0 Major facilitator Superfamily HUU83_RS05250 ENOG4105CGH 5'-nucleotidase HUU83_RS05255 ENOG4108Z66 YbaK ebsC protein HUU83_RS05260 ENOG4105MBR gumn family HUU83_RS05265 ENOG41081XE plasmid maintenance system antidote protein, xre family HUU83_RS05270 ENOG4105C59 p-type ATPase HUU83_RS05275 ENOG4105CSV Glutaminase HUU83_RS05280 ENOG4107RY6 amino acid HUU83_RS05285 ENOG4108Z6Z Transcriptional regulator HUU83_RS05290 ENOG4105G5H Membrane HUU83_RS05295 ENOG4107QX8 SPFH domain, Band 7 family protein HUU83_RS05300 ENOG41083J0 (ABC) transporter HUU83_RS05305 ENOG4105C4B ABC transporter, permease HUU83_RS05310 ENOG4107QR8 Thioredoxin HUU83_RS05315 ENOG4105E1F short-chain dehydrogenase reductase HUU83_RS05320 ENOG4108UJV acyl-CoA thioesterase i HUU83_RS05325 ENOG4108I0Y (ABC) transporter HUU83_RS05330 ENOG4105CV6 ABC transporter, permease HUU83_RS05335 ENOG4105CNA YD repeat protein HUU83_RS05365 ENOG4107653 Transcriptional regulator HUU83_RS05375 ENOG4108N16 Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region HUU83_RS05380 ENOG41060W2 glyoxylate carboligase HUU83_RS05385 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) HUU83_RS05395 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease HUU83_RS05405 ENOG4105DTE Xanthine uracil vitamin C permease HUU83_RS05410 ENOG4105BZW Glycerate kinase HUU83_RS05415 ENOG4105S0E allantoin catabolism protein HUU83_RS05420 ENOG4105CE7 Amidase, hydantoinase carbamoylase family HUU83_RS05425 ENOG4105DG4 malate L-lactate dehydrogenase HUU83_RS05430 ENOG4107R1Q Membrane protein FdrA HUU83_RS05435 ENOG4107REC cytoplasmic protein HUU83_RS05440 ENOG4105G5A Protein of unknown function (DUF2877) HUU83_RS05445 ENOG4105C5B carbamate kinase HUU83_RS05450 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit HUU83_RS05455 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) HUU83_RS05465 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) HUU83_RS05475 ENOG4105S2T inner membrane protein YbcI HUU83_RS05480 ENOG4105WQ3 Rna-binding protein HUU83_RS05485 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) HUU83_RS05490 ENOG4108WDE Fimbrial protein HUU83_RS05495 ENOG4108AF8 Chaperone HUU83_RS05500 ENOG4105CW0 outer membrane usher protein HUU83_RS05505 ENOG4108M66 Involved in regulation of length and mediation of adhesion of SfmA fimbriae (but not necessary for the production of fimbriae). Seems to be mannose binding adhesin (By similarity) HUU83_RS05510 ENOG4108ZI2 Fimbrial protein HUU83_RS05515 ENOG4108Q9V regulatoR HUU83_RS05530 ENOG4105QUW HUU83_RS05535 ENOG41090FC Bacteriophage N4 receptor, outer membrane subunit HUU83_RS05545 ENOG410600T transposase HUU83_RS05560 ENOG4105CNA YD repeat protein HUU83_RS05600 ENOG4105CNA YD repeat protein HUU83_RS05610 ENOG4105CS6 Rhs element vgr protein HUU83_RS05615 ENOG4105GR3 Histidine kinase HUU83_RS05620 ENOG4105CK6 Two component transcriptional regulator (Winged helix family HUU83_RS05625 ENOG4105ENJ RND efflux system, outer membrane lipoprotein HUU83_RS05630 ENOG410624V efflux system protein HUU83_RS05635 ENOG4105EP1 Efflux transporter rnd family, mfp subunit HUU83_RS05640 ENOG4108IJF Heavy metal efflux pump, CzcA HUU83_RS05645 ENOG4105C85 amino acid HUU83_RS05650 ENOG4105CUY Mechanosensitive ion channel HUU83_RS05655 ENOG4108RCM Nitroreductase HUU83_RS05660 ENOG4105MSB protein, conserved in bacteria HUU83_RS05665 ENOG4105WQ6 Membrane HUU83_RS05675 ENOG4107635 Hok Gef family protein HUU83_RS05685 ENOG4108TSE Transferase HUU83_RS05690 ENOG4107RNH Outer membrane receptor FepA HUU83_RS05695 ENOG4105E93 esterase HUU83_RS05700 ENOG41085A6 mbth domain-containing protein HUU83_RS05705 ENOG4105C0W non-ribosomal peptide synthetase HUU83_RS05710 ENOG4108QY5 Ferric enterobactin transport protein HUU83_RS05715 ENOG4105E0A ABC, transporter HUU83_RS05720 ENOG4105TVJ transport system, permease HUU83_RS05725 ENOG4105DQ5 transport system permease protein HUU83_RS05735 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein HUU83_RS05740 ENOG4105E4F Isochorismate synthase HUU83_RS05745 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase HUU83_RS05750 ENOG4105WQI isochorismatase HUU83_RS05755 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase HUU83_RS05760 ENOG4108TZA Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules (By similarity) HUU83_RS05765 ENOG4105D22 carbon starvation protein HUU83_RS05770 ENOG4105VCD cytoplasmic protein HUU83_RS05775 ENOG4107SCQ Iron-containing alcohol dehydrogenase HUU83_RS05780 ENOG4105CHM Aminotransferase HUU83_RS05785 ENOG4105GTN ParB Domain Protein Nuclease HUU83_RS05790 ENOG4105BZV Phosphoadenosine phosphosulfate reductase HUU83_RS05795 ENOG4105DQS Transcriptional regulator HUU83_RS05800 ENOG4108KHN disulfide isomerase, thiol-disulfide oxidase HUU83_RS05805 ENOG4105D3R alkyl hydroperoxide reductase HUU83_RS05810 ENOG4108JU3 Alkyl hydroperoxide reductase HUU83_RS05815 ENOG4108U51 Universal stress protein HUU83_RS05820 ENOG4105E2A Dehydrogenase HUU83_RS05825 ENOG4105NXH GreA GreB family elongation factor HUU83_RS05830 ENOG4105KTS ribonuclease HUU83_RS05835 ENOG4107QPK )-transporter HUU83_RS05850 ENOG4105CHY citrate lyase, alpha HUU83_RS05855 ENOG4105CI0 Citrate lyase HUU83_RS05865 ENOG4105DUA (citrate (pro-3S)-lyase ligase HUU83_RS05870 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism HUU83_RS05875 ENOG4106YYS transcriptional regulatory protein HUU83_RS05880 ENOG4105CEE C4-dicarboxylate transporter HUU83_RS05885 ENOG41079UR PagP is required both for biosynthesis of hepta-acylated lipid A species containing palmitate and for resistance to cationic antimicrobial peptides (CAMPs). It catalyzes the transfer of a palmitate chain (16 0) from the sn-1 position of a glycerophospholipid to the free hydroxyl group of the (R)-3- hydroxymyristate chain at position 2 of lipid A (endotoxin) (By similarity) HUU83_RS05905 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) HUU83_RS05915 ENOG41064T2 transcriptional regulator, lysR family HUU83_RS05930 ENOG4105DZ1 carboxypeptidase HUU83_RS05935 ENOG4105K6T rare lipoprotein A HUU83_RS05940 ENOG4105CNI cell division protein FtsW HUU83_RS05945 ENOG4105CJN penicillin-binding protein HUU83_RS05955 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) HUU83_RS05960 ENOG4108TGR phosphatase HUU83_RS05970 ENOG4105DJF DNA polymerase III, delta' subunit HUU83_RS05985 ENOG4107PAI alpha helical protein HUU83_RS05990 ENOG4105EUU Sel1 domain protein repeat-containing protein HUU83_RS05995 ENOG41069CF Protein of unknown function (DUF1266) HUU83_RS06000 ENOG4105QFC Hsc56 co-chaperone of HscC HUU83_RS06005 ENOG4107JFD Sel1 repeat HUU83_RS06010 ENOG41069CF Protein of unknown function (DUF1266) HUU83_RS06015 ENOG4105QFC Hsc56 co-chaperone of HscC HUU83_RS06020 ENOG4105F7F Chaperone HUU83_RS06030 ENOG4105CDA abc transporter atp-binding protein HUU83_RS06035 ENOG4105DRP amino acid AbC transporter HUU83_RS06040 ENOG4105EAD ABC transporter HUU83_RS06045 ENOG4107RP9 extracellular solute-binding protein, family 3 HUU83_RS06050 ENOG4107U91 Rhomboid family HUU83_RS06055 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) HUU83_RS06060 ENOG4108JU5 Magnesium and cobalt efflux protein HUU83_RS06070 ENOG4105C9A Phoh family HUU83_RS06080 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family HUU83_RS06120 ENOG4105CAQ asparagine synthetase HUU83_RS06125 ENOG4105D4U had-superfamily hydrolase, subfamily iia HUU83_RS06130 ENOG4105E2R ROK family HUU83_RS06135 ENOG4105CE4 GlcNAc 6-P deacetylase HUU83_RS06145 ENOG4105CI1 PTS System HUU83_RS06160 ENOG4105GX6 (LipO)protein HUU83_RS06165 ENOG41090R7 Ferric uptake HUU83_RS06175 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) HUU83_RS06180 ENOG4105NNH LexA regulated protein HUU83_RS06185 ENOG4105EV9 Alpha Beta Hydrolase HUU83_RS06190 ENOG4107CDU Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity) HUU83_RS06195 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 HUU83_RS06200 ENOG4105D5Q Arginine ornithine antiporter HUU83_RS06205 ENOG4105CXN decarboxylase HUU83_RS06215 ENOG4105EEX Two component transcriptional regulator (Winged helix family HUU83_RS06220 ENOG4105C08 Histidine kinase HUU83_RS06245 ENOG4105XIQ Protein of unknown function (DUF2517) HUU83_RS06250 ENOG4105CNA YD repeat protein HUU83_RS06255 ENOG41079JQ Membrane HUU83_RS06275 ENOG4106R09 HUU83_RS06290 ENOG4107SEY Conserved Protein HUU83_RS06295 ENOG4105CVP deoxyribo-dipyrimidine photolyase HUU83_RS06300 ENOG4105DUX Transporter HUU83_RS06305 ENOG4107QNR UPF0135 protein HUU83_RS06310 ENOG4105P4J Allophanate hydrolase, subunit 1 HUU83_RS06315 ENOG4107R7A Allophanate hydrolase subunit 2 HUU83_RS06320 ENOG4105E7W lamb ycsf family protein HUU83_RS06330 ENOG4108KK1 membrane protein AbrB duplication HUU83_RS06335 ENOG4108MY7 Fimbrial HUU83_RS06340 ENOG4108TTM chaperone HUU83_RS06345 ENOG4106PG1 outer membrane usher protein HUU83_RS06350 ENOG4106UBK fimbrial-like adhesin protein HUU83_RS06355 ENOG4105BZN citrate synthase HUU83_RS06365 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit HUU83_RS06370 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein HUU83_RS06375 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) HUU83_RS06380 ENOG4105E33 succinate dehydrogenase HUU83_RS06385 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 HUU83_RS06390 ENOG4105C7S Dehydrogenase HUU83_RS06400 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha HUU83_RS06405 ENOG4105FDP GntR family transcriptional regulator HUU83_RS06410 ENOG4105DM4 PTS System HUU83_RS06415 ENOG4105C8I hydrolase, family 38 HUU83_RS06420 ENOG4105C4M (Ubiquinol oxidase) subunit I HUU83_RS06425 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii HUU83_RS06435 ENOG4105KJB cyd operon protein YbgE HUU83_RS06440 ENOG4107YD3 Thioesterase HUU83_RS06445 ENOG4105E02 MotA TolQ exbB proton channel HUU83_RS06455 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA HUU83_RS06465 ENOG4105KCK Peptidoglycan-associated lipoprotein HUU83_RS06470 ENOG4105UFD tol-pal system protein YbgF HUU83_RS06520 ENOG4106Z1T Nicotinamide Mononucleotide Transporter HUU83_RS06525 ENOG4105PGM cation diffusion facilitator family transporter HUU83_RS06530 ENOG4105JND homeobox protein HUU83_RS06535 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) HUU83_RS06545 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) HUU83_RS06555 ENOG4105F0Z galactose-1-phosphate uridylyltransferase HUU83_RS06560 ENOG4105CMR udp-glucose 4-epimerase HUU83_RS06565 ENOG4105DKW ABC transporter HUU83_RS06570 ENOG4105F4R Transcriptional regulator mode HUU83_RS06580 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein HUU83_RS06585 ENOG4105E0C molybdate abc transporter HUU83_RS06595 ENOG4108K4B hydrolase HUU83_RS06605 ENOG4105F04 LysR family Transcriptional regulator HUU83_RS06610 ENOG4105C7F AcnD-accessory protein PrpF HUU83_RS06615 ENOG4107QPK )-transporter HUU83_RS06620 ENOG4107QM5 aconitate hydratase HUU83_RS06625 ENOG4105NBR Pectinesterase HUU83_RS06630 ENOG4108I1J Integrase HUU83_RS06750 ENOG4105NY2 NinB protein HUU83_RS06785 ENOG4105HRS Antitermination protein HUU83_RS06815 ENOG4105QFS Lysis protein S homolog from lambdoid prophage HUU83_RS06820 ENOG4105KUS lysozyme HUU83_RS06825 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 HUU83_RS06835 ENOG41064WM Uncharacterized protein YcgX HUU83_RS06840 ENOG4106YSC HUU83_RS06845 ENOG4105FKG DNA packaging protein HUU83_RS06850 ENOG4105UZW Tail fiber assembly protein HUU83_RS06855 ENOG4107DE1 head-to-tail joining protein HUU83_RS06865 ENOG4105F7J membrane-bound serine protease HUU83_RS06875 ENOG4105IM0 capsid protein HUU83_RS06960 ENOG4108X9F tail fiber protein HUU83_RS06965 ENOG4105UZW Tail fiber assembly protein HUU83_RS06970 ENOG4106KTS Inner membrane protein yeaI HUU83_RS06975 ENOG4108V1U phospholipid-binding protein HUU83_RS06980 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) HUU83_RS06995 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) HUU83_RS07000 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) HUU83_RS07010 ENOG4105CHW UPF0052 protein HUU83_RS07020 ENOG4108RIR Molybdenum cofactor biosynthesis protein HUU83_RS07030 ENOG4105M00 molybdopterin converting factor, subunit 1 HUU83_RS07035 ENOG4108ZAF Molybdopterin HUU83_RS07040 ENOG4105HFZ Membrane HUU83_RS07045 ENOG410733J conserved inner membrane protein HUU83_RS07050 ENOG4107UXM Membrane HUU83_RS07055 ENOG4105DZQ phospholipase D Transphosphatidylase HUU83_RS07060 ENOG4105X23 Endonuclease Exonuclease phosphatase HUU83_RS07065 ENOG4105I9U inner membrane protein ybhQ HUU83_RS07070 ENOG4107QWP ABC-2 type transporter HUU83_RS07075 ENOG4107QWP ABC-2 type transporter HUU83_RS07080 ENOG4105CJ1 ABC, transporter HUU83_RS07090 ENOG4107MVR Transcriptional regulator HUU83_RS07095 ENOG4105C1J atp-dependent rna helicase HUU83_RS07100 ENOG4108UV1 cellular component movement HUU83_RS07105 ENOG4105DVT helicase HUU83_RS07110 ENOG4108MTB glycosyl transferase family HUU83_RS07115 ENOG4105DG4 malate L-lactate dehydrogenase HUU83_RS07120 ENOG4105VR4 UPF0379 protein ybiJ HUU83_RS07125 ENOG4105KSC Transcriptional regulator, TraR DksA family HUU83_RS07135 ENOG4108IU3 tonb-dependent siderophore receptor HUU83_RS07140 ENOG4105ZY9 UPF0379 protein ybiM HUU83_RS07150 ENOG4105D8X mechanosensitive ion channel HUU83_RS07155 ENOG4105CDA abc transporter atp-binding protein HUU83_RS07160 ENOG4105E5Q amino acid AbC transporter HUU83_RS07165 ENOG4107R0W ABC transporter HUU83_RS07175 ENOG4107AQZ Membrane HUU83_RS07185 ENOG4108T1M outer membrane protein x HUU83_RS07190 ENOG4108I6E Sulfatase HUU83_RS07200 ENOG4105KST dependent repressor HUU83_RS07205 ENOG4105F4P )-transporter HUU83_RS07210 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein HUU83_RS07215 ENOG4105C5H ABC transporter HUU83_RS07225 ENOG41072TH Protein of unknown function (DUF1479) HUU83_RS07230 ENOG4108HCJ Hydrolase HUU83_RS07240 ENOG4105F1A Pyruvate formate-lyase HUU83_RS07245 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) HUU83_RS07250 ENOG4105D06 uba thif-type nad fad binding protein HUU83_RS07255 ENOG4105CVM Molybdenum cofactor synthesis domain protein HUU83_RS07260 ENOG4105D44 asparaginase HUU83_RS07285 ENOG4105BZU Histidine kinase HUU83_RS07290 ENOG41064RH membrane protein YliF HUU83_RS07300 ENOG4105UFT Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway HUU83_RS07305 ENOG4105D8V Glucose sorbosone dehydrogenase HUU83_RS07310 ENOG4108TGY Glutathione S-transferase HUU83_RS07315 ENOG4105DZ1 carboxypeptidase HUU83_RS07320 ENOG4107FB0 transcriptional regulator DeoR family HUU83_RS07325 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase HUU83_RS07330 ENOG4107QF7 multi-drug HUU83_RS07340 ENOG4108HCJ Hydrolase HUU83_RS07345 ENOG4106UW1 Major Facilitator superfamily HUU83_RS07350 ENOG4108RFG Tetr family transcriptional regulator HUU83_RS07360 ENOG4105GWF inner membrane protein YbjM HUU83_RS07365 ENOG41090BQ Glutaredoxin HUU83_RS07370 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress HUU83_RS07385 ENOG4108RMJ sensory transduction regulator HUU83_RS07390 ENOG4107RUE extracellular solute-binding protein family 1 HUU83_RS07395 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) HUU83_RS07400 ENOG4105F38 ABC transporter, permease HUU83_RS07405 ENOG4105D38 putrescine abc transporter HUU83_RS07410 ENOG4105RBQ inner membrane protein ybjO HUU83_RS07420 ENOG4106TNF Periplasmic binding protein HUU83_RS07425 ENOG4105DMR ABC, transporter HUU83_RS07430 ENOG4105GBT ABC transporter HUU83_RS07435 ENOG4106PMH Extracellular solute-binding protein family 3 HUU83_RS07440 ENOG4105E5Z arginine transporter ATP-binding subunit HUU83_RS07445 ENOG41064MM (LipO)protein HUU83_RS07455 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase HUU83_RS07460 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase HUU83_RS07465 ENOG4105CGD Nad-dependent epimerase dehydratase HUU83_RS07470 ENOG4105C5W Aldolase HUU83_RS07475 ENOG4105C7K acetolactate synthase HUU83_RS07480 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) HUU83_RS07490 ENOG4105DWU Membrane HUU83_RS07495 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) HUU83_RS07500 ENOG4105CPB ATP-dependent endonuclease of the OLD family HUU83_RS07505 ENOG4108MJ5 VirK protein HUU83_RS07510 ENOG4105DJY efflux transporter, rnd family, mfp subunit HUU83_RS07520 ENOG4105VEQ Cold shock protein HUU83_RS07530 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit HUU83_RS07540 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) HUU83_RS07550 ENOG4108JJ8 (ABC) transporter HUU83_RS07555 ENOG4108JJ9 ABC, transporter HUU83_RS07560 ENOG4105C3M thioredoxin reductase HUU83_RS07570 ENOG4105CNU cell division protein FtsK HUU83_RS07580 ENOG4105D1H recombination factor protein RarA HUU83_RS07590 ENOG4107QY8 reductase HUU83_RS07595 ENOG4105QAX Iron-sulfur HUU83_RS07600 ENOG4107KGK dmso reductase anchor subunit HUU83_RS07605 ENOG4105CHJ isochorismatase hydrolase HUU83_RS07615 ENOG4105E5D amino acid HUU83_RS07620 ENOG410642W LysR family Transcriptional regulator HUU83_RS07625 ENOG4108X0B nad(p)h dehydrogenase (quinone) HUU83_RS07630 ENOG4105F1A Pyruvate formate-lyase HUU83_RS07635 ENOG4105C6N Formate acetyltransferase HUU83_RS07640 ENOG4105TMB Formate nitrite transporter HUU83_RS07645 ENOG4105DDY UPF0142 protein ycaO HUU83_RS07650 ENOG4107VMU Membrane HUU83_RS07665 ENOG4108K0D peptidase, M48 HUU83_RS07675 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) HUU83_RS07685 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 HUU83_RS07690 ENOG4105BZ1 (ABC) transporter HUU83_RS07700 ENOG4105T0Z Conserved Protein HUU83_RS07715 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups HUU83_RS07720 ENOG4107S90 membrAne HUU83_RS07725 ENOG4106371 Methyltransferase HUU83_RS07735 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) HUU83_RS07745 ENOG4105DIT ErfK YbiS YcfS YnhG family protein HUU83_RS07750 ENOG4105EAQ (twin-arginine translocation) pathway signal HUU83_RS07755 ENOG4105C5X domain protein HUU83_RS07765 ENOG4105CGF Aromatic amino acid aminotransferase HUU83_RS07770 ENOG4105FCK Membrane HUU83_RS07785 ENOG4105CD8 aminopeptidase N HUU83_RS07795 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component HUU83_RS07805 ENOG4105GVF (ABC) transporter HUU83_RS07810 ENOG4108UZX fmn reductase HUU83_RS07815 ENOG41071VI Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. ElfA is the major fimbrial subunit produced by this operon HUU83_RS07820 ENOG4106JJN Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. Could be required for the biogenesis of the ElfA fimbriae HUU83_RS07825 ENOG4105CW0 outer membrane usher protein HUU83_RS07830 ENOG4108MDY Fimbrial HUU83_RS07835 ENOG4105Q7J Fimbrial HUU83_RS07840 ENOG4105MX3 Fimbrial HUU83_RS07845 ENOG4106PH7 chaperone HUU83_RS07855 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) HUU83_RS07860 ENOG4105QVC MOSC domain-containing protein HUU83_RS07870 ENOG4105C5H ABC transporter HUU83_RS07875 ENOG4105F1S paraquat-inducible protein a HUU83_RS07880 ENOG4105DY2 Paraquat-inducible protein b HUU83_RS07885 ENOG4108Q2G (LipO)protein HUU83_RS07890 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) HUU83_RS07900 ENOG4105DAN ATP-dependent protease HUU83_RS07910 ENOG4105UYK outer membrane protein a HUU83_RS07920 ENOG4108RZ1 DNA transformation protein HUU83_RS07925 ENOG4105EM2 membrane HUU83_RS07930 ENOG410901E Membrane HUU83_RS07935 ENOG41088T4 Helicase IV HUU83_RS07950 ENOG4105K4P CoA-binding domain protein HUU83_RS07965 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 HUU83_RS07970 ENOG4108Z0T Part of a sulfur-relay system (By similarity) HUU83_RS07975 ENOG4108MN8 Membrane HUU83_RS07985 ENOG4105E3S small subunit HUU83_RS07990 ENOG4105DPX Hydrogenase, large subunit HUU83_RS07995 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit HUU83_RS08000 ENOG4108USZ hydrogenase HUU83_RS08005 ENOG4108VXY Hydrogenase-1 operon protein HyaE HUU83_RS08010 ENOG4105MVP hydrogenase-1 operon protein HyaF HUU83_RS08015 ENOG4105C4M (Ubiquinol oxidase) subunit I HUU83_RS08020 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii HUU83_RS08030 ENOG4105D6F Phosphatase HUU83_RS08035 ENOG4105D75 Capsular exopolysaccharide family HUU83_RS08040 ENOG4107ZF2 Phosphatase HUU83_RS08045 ENOG4105DAY polysaccharide export protein HUU83_RS08050 ENOG4105E3R (LipO)protein HUU83_RS08055 ENOG4108W78 Pfam:DUF1017 HUU83_RS08060 ENOG4108Y9B (LipO)protein HUU83_RS08070 ENOG41060EU Cold shock-like protein HUU83_RS08075 ENOG4105VEQ Cold shock protein HUU83_RS08090 ENOG4106H71 Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation HUU83_RS08095 ENOG4105HEE Binding Domain protein HUU83_RS08100 ENOG4105BZU Histidine kinase HUU83_RS08105 ENOG4108SV3 Tmao reductase system periplasmic protein tort HUU83_RS08110 ENOG4106WF9 DNA-binding transcriptional regulator TorR HUU83_RS08115 ENOG4105CUW cytochrome C-TYPE protein HUU83_RS08120 ENOG4107QY8 reductase HUU83_RS08125 ENOG4108SBI Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity) HUU83_RS08145 ENOG4105D6F Phosphatase HUU83_RS08150 ENOG4105XH3 HUU83_RS08160 ENOG4105XF5 Escherichia coli IMT2125 genomic chromosome, IMT2125 HUU83_RS08165 ENOG4105C2W permease HUU83_RS08200 ENOG4108R86 Transcriptional regulator HUU83_RS08205 ENOG4105C26 Dehydrogenase HUU83_RS08215 ENOG4105CK7 Sodium proline symporter HUU83_RS08225 ENOG410650H (LipO)protein HUU83_RS08230 ENOG4105DBE peroxidase HUU83_RS08235 ENOG4105D5M phosphate starvation-inducible protein HUU83_RS08245 ENOG4105CND Glycosyl transferase, family 2 HUU83_RS08250 ENOG4107BJW polysaccharide deacetylase HUU83_RS08255 ENOG4108TUY outer membrane protein PgaA HUU83_RS08260 ENOG4105BZU Histidine kinase HUU83_RS08275 ENOG4108T85 Membrane HUU83_RS08290 ENOG4105JPG D-isomer specific 2-hydroxyacid dehydrogenase HUU83_RS08300 ENOG4107XHZ cytoplasmic chaperone TorD family protein HUU83_RS08305 ENOG4108UQ5 membrane protein YcdZ HUU83_RS08310 ENOG4105P8Q Curli production assembly transport component CsgG HUU83_RS08315 ENOG4108WYR Curli production assembly transport component, CsgF HUU83_RS08320 ENOG4108XDW curli assembly protein CsgE HUU83_RS08325 ENOG41086KC Transcriptional regulator HUU83_RS08330 ENOG4108U0V Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin. The minor subunit is the nucleation component of curlin monomers HUU83_RS08335 ENOG4105G76 Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin HUU83_RS08350 ENOG4108UVJ appr-1-p processing domain protein HUU83_RS08355 ENOG4107RZC phospholipase d HUU83_RS08370 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) HUU83_RS08375 ENOG4105NAC (LipO)protein HUU83_RS08380 ENOG4108W47 Acidic protein msyB HUU83_RS08390 ENOG4105D1S lipid A biosynthesis HUU83_RS08400 ENOG4108YYC ycei family HUU83_RS08405 ENOG4105DS1 cytochrome b561 HUU83_RS08410 ENOG4106974 biofilm formation HUU83_RS08420 ENOG4105PVA Biofilm formation regulatory protein BssS HUU83_RS08425 ENOG4105MEA DNA damage-inducible protein i HUU83_RS08435 ENOG4105F3T (LipO)protein HUU83_RS08440 ENOG4105E9S glutaredoxin 2 HUU83_RS08450 ENOG4105D9U N-acetyltransferase HUU83_RS08460 ENOG4105EP9 oxidoreductase HUU83_RS08465 ENOG4105CJR Integral membrane protein (MviN HUU83_RS08470 ENOG4105QVD Flagella synthesis protein FlgN HUU83_RS08475 ENOG4105M9M anti-sigma28 factor FlgM HUU83_RS08480 ENOG4105CKS Flagella basal body P-ring formation protein flgA HUU83_RS08485 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) HUU83_RS08490 ENOG4108ZC9 flagellar basal-body rod protein flgc HUU83_RS08495 ENOG4105W00 Flagellar hook capping protein HUU83_RS08500 ENOG4105BZE flagellar hook protein, FlgE HUU83_RS08505 ENOG4108KPB Flagellar basal-body rod protein FlgF HUU83_RS08510 ENOG4105CGA flagellar basal-body rod protein FlgG HUU83_RS08525 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj HUU83_RS08530 ENOG4105E1Q flagellar hook-associated protein HUU83_RS08535 ENOG4105DTJ flagellar hook-associated protein HUU83_RS08540 ENOG4107QQB Ribonuclease E HUU83_RS08545 ENOG4105EI2 Pseudouridine synthase HUU83_RS08550 ENOG4108UHJ MAF-like protein HUU83_RS08555 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein HUU83_RS08575 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase HUU83_RS08580 ENOG4105CHR reductase HUU83_RS08585 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) HUU83_RS08590 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) HUU83_RS08595 ENOG4105YAZ 4-amino-4-deoxychorismate lyase HUU83_RS08600 ENOG4105HHA aminodeoxychorismate lyase HUU83_RS08610 ENOG4107QRG dna polymerase iii HUU83_RS08615 ENOG4105F8V Hydrolase, tatD family HUU83_RS08620 ENOG4105CI1 PTS System HUU83_RS08625 ENOG4105CNM Receptor HUU83_RS08630 ENOG4105K59 histidine triad (HIT) protein HUU83_RS08635 ENOG41090DQ Lipoprotein HUU83_RS08640 ENOG4108WEF Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity) HUU83_RS08660 ENOG4105CEP NADH dehydrogenase HUU83_RS08665 ENOG4107MBR 17 kDa surface antigen HUU83_RS08670 ENOG4108IND Tetr family transcriptional regulator HUU83_RS08675 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction HUU83_RS08680 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein HUU83_RS08685 ENOG4108JA2 transcriptioN-repair coupling factor HUU83_RS08690 ENOG4105IQC Inner membrane protein YcfT HUU83_RS08695 ENOG4105D60 lipoprotein releasing system transmembrane protein HUU83_RS08700 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) HUU83_RS08705 ENOG4105D60 lipoprotein releasing system transmembrane protein HUU83_RS08715 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) HUU83_RS08730 ENOG4107RUE extracellular solute-binding protein family 1 HUU83_RS08735 ENOG4105D38 putrescine abc transporter HUU83_RS08755 ENOG4105EZE Cupin 4 family protein HUU83_RS08760 ENOG4105IFJ Histidine kinase HUU83_RS08765 ENOG4105XJC Two component transcriptional regulator (Winged helix family HUU83_RS08770 ENOG4107QTF adenylosuccinate lyase HUU83_RS08790 ENOG4108R99 pseudouridine synthase HUU83_RS08795 ENOG4108HMX isocitrate dehydrogenase (NADP) HUU83_RS08820 ENOG4108I1J Integrase HUU83_RS08825 ENOG4105QYW Excisionase-like protein from lambdoid prophage 14 HUU83_RS08830 ENOG4108R7K Metal Dependent Phosphohydrolase HUU83_RS08835 ENOG4108HJ1 Uncharacterized conserved protein (DUF2303) HUU83_RS08840 ENOG4105H40 HUU83_RS08865 ENOG4108S1U HUU83_RS08895 ENOG4106CZA Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC (By similarity) HUU83_RS08905 ENOG4108MXB Protein of unknown function (DUF968) HUU83_RS08910 ENOG4105HGD Antitermination protein HUU83_RS08930 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 HUU83_RS08950 ENOG4105CAR Terminase, large subunit HUU83_RS08960 ENOG4105EFC phage portal protein HK97 family HUU83_RS09005 ENOG4105TKZ Tail Sheath HUU83_RS09025 ENOG4108NKR DNA circulation protein HUU83_RS09045 ENOG4108T86 baseplate J family protein HUU83_RS09050 ENOG4105Y0G tail protein HUU83_RS09055 ENOG4105Y9F tail fiber protein HUU83_RS09060 ENOG4108US3 tail fiber assembly HUU83_RS09065 ENOG4105PTU response to oxidative stress HUU83_RS09075 ENOG4108C33 Resolvase HUU83_RS09080 ENOG4105Y50 Virulence Protein HUU83_RS09095 ENOG4108RAV Conserved protein HUU83_RS09110 ENOG4108HMX isocitrate dehydrogenase (NADP) HUU83_RS09130 ENOG41064WM Uncharacterized protein YcgX HUU83_RS09135 ENOG4108XDN Transcriptional regulator HUU83_RS09140 ENOG4105BZU Histidine kinase HUU83_RS09145 ENOG4105WKE Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. Partially antagonizes the activities of YmgA and AriR, proteins that, via the Rcs phosphorelay, promote the synthesis of colanic acid, an exopolysaccharide and matrix component HUU83_RS09150 ENOG41077SS Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. May serve to stimulate biofilm maturation, probably via the Rcs phosphorelay. Mild overexpression at 16 degrees Celsius increases the production of colanic acid, an exopolysaccharide and matrix component, and reduces adhesive curli fimbriae expression. Both of these effects require RcsB HUU83_RS09160 ENOG410738I uncharacterized protein ymgC HUU83_RS09165 ENOG4105BZU Histidine kinase HUU83_RS09185 ENOG410658X HUU83_RS09220 ENOG4107QMS site-determining protein HUU83_RS09230 ENOG4105S66 prophage protein HUU83_RS09235 ENOG41066UD Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium HUU83_RS09245 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase HUU83_RS09255 ENOG4106PXS Toxin, which has some hemolytic activity towards mammalian cells. Acts by forming a pore-like structure upon contact with mammalian cells HUU83_RS09260 ENOG4105KT5 UmuD protein HUU83_RS09265 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) HUU83_RS09270 ENOG410635M Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity) HUU83_RS09285 ENOG4105ED1 spovr family HUU83_RS09295 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) HUU83_RS09305 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A HUU83_RS09315 ENOG4108T7K Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity) HUU83_RS09335 ENOG4105VDH Dihydroxyacetone kinase HUU83_RS09340 ENOG4108UTZ Dihydroxyacetone kinase HUU83_RS09345 ENOG4105CMT Dihydroxyacetone kinase HUU83_RS09350 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family HUU83_RS09355 ENOG4105I1J Autotransporter HUU83_RS09360 ENOG4105C3G gtp-binding protein HUU83_RS09370 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria HUU83_RS09375 ENOG4105CHH sulfate transporter HUU83_RS09380 ENOG4105C5T Phosphoribosyl pyrophosphate synthase HUU83_RS09405 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) HUU83_RS09410 ENOG4108YY7 Invasion gene expression up-regulator SirB HUU83_RS09415 ENOG41063JG Transcriptional regulator HUU83_RS09440 ENOG4105EWV Sodium calcium exchanger membrane region HUU83_RS09445 ENOG4105WS7 Cation transport regulator HUU83_RS09450 ENOG4108NH8 Cation transport protein HUU83_RS09455 ENOG41090EX DsrE family HUU83_RS09460 ENOG4105ID0 Putative invasin HUU83_RS09465 ENOG4105WH1 Two component transcriptional regulator luxr family HUU83_RS09470 ENOG4105BZU Histidine kinase HUU83_RS09475 ENOG4105DQQ Major facilitator superfamily MFS_1 HUU83_RS09480 ENOG4105CRU nitrate reductase, alpha subunit HUU83_RS09485 ENOG4108IUE nitrate reductase beta subunit HUU83_RS09490 ENOG4105R3A Nitrate reductase HUU83_RS09495 ENOG41076YT nitrate reductase, gamma subunit HUU83_RS09515 ENOG4105CIY formyltetrahydrofolate deformylase HUU83_RS09520 ENOG4105K5B UPF0225 protein HUU83_RS09525 ENOG4105D78 K07001 NTE family protein HUU83_RS09530 ENOG4105I93 response regulator HUU83_RS09535 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase HUU83_RS09540 ENOG4108SAU DNA-binding protein H-ns HUU83_RS09545 ENOG4107104 thymidine kinase HUU83_RS09555 ENOG4105C0A alcohol dehydrogenase HUU83_RS09560 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein HUU83_RS09570 ENOG4108J59 Extracellular solute-binding protein, family 5 HUU83_RS09575 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HUU83_RS09580 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HUU83_RS09585 ENOG4105C3U ABC transporter HUU83_RS09590 ENOG4108JQ7 (ABC) transporter HUU83_RS09610 ENOG4107SVH Potassium channel protein HUU83_RS09615 ENOG4105K9H YciI-like protein HUU83_RS09620 ENOG410822N TonB family HUU83_RS09625 ENOG4105NAU thioesterase Superfamily protein HUU83_RS09645 ENOG4105EIF outer membrane protein W HUU83_RS09650 ENOG4108N8X transition metal ion binding HUU83_RS09655 ENOG4108Z9Z response to DNA damage stimulus HUU83_RS09675 ENOG4105DK0 Indole-3-glycerol phosphate synthase HUU83_RS09680 ENOG4108EFP Anthranilate synthase component II HUU83_RS09685 ENOG4105CRQ synthase (Component I) HUU83_RS09695 ENOG4105DB7 PHP domain protein HUU83_RS09700 ENOG4107RTD sua5 ycio yrdc ywlc family protein HUU83_RS09705 ENOG4105FE9 pseudouridine synthase HUU83_RS09710 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase HUU83_RS09715 ENOG4105UBK short-chain dehydrogenase reductase HUU83_RS09720 ENOG4105ERU peptidase HUU83_RS09725 ENOG4105RKX Protein of unknown function (DUF2498) HUU83_RS09730 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) HUU83_RS09735 ENOG4107R11 Transcriptional regulator HUU83_RS09755 ENOG4107QM5 aconitate hydratase HUU83_RS09765 ENOG4105EYK Phosphatidylglycerophosphatase B HUU83_RS09770 ENOG4105Q4A inner membrane protein yciS HUU83_RS09775 ENOG4105CFV Tetratricopeptide repeat protein HUU83_RS09785 ENOG4108ZJT translation initiation factor, Sui1 HUU83_RS09795 ENOG4105N2W Transcriptional regulator HUU83_RS09800 ENOG410643D UPF0509 protein HUU83_RS09805 ENOG4105BZU Histidine kinase HUU83_RS09820 ENOG4105Q4T oxidoreductase HUU83_RS09825 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH HUU83_RS09830 ENOG4105WDY DNA (cytosine-5-)-methyltransferase HUU83_RS09835 ENOG4108JQ2 peptide transport system atp-binding protein HUU83_RS09840 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein HUU83_RS09845 ENOG4108EU3 peptide transport system, permease HUU83_RS09850 ENOG4108I5W peptide transport system, permease protein HUU83_RS09855 ENOG4108HIY periplasmic HUU83_RS09860 ENOG4105N0E Protein of unknown function (DUF2543) HUU83_RS09865 ENOG4105CUB amino acid HUU83_RS09875 ENOG4105CFQ glutamine synthetase HUU83_RS09880 ENOG4108Z86 Glutamine amidotransferase HUU83_RS09885 ENOG4107VRI Transcriptional regulator HUU83_RS09890 ENOG4105C26 Dehydrogenase HUU83_RS09895 ENOG4105CJP fad dependent oxidoreductase HUU83_RS09900 ENOG4108JPW Aminotransferase HUU83_RS09905 ENOG4105E51 psp operon transcriptional activator HUU83_RS09910 ENOG41087YS Phage shock protein A HUU83_RS09915 ENOG4105YYT phage shock protein B HUU83_RS09920 ENOG4105FM1 phage shock protein C HUU83_RS09925 ENOG4105NNG Peripheral inner membrane phage-shock protein HUU83_RS09930 ENOG4105K8Z Phage shock protein HUU83_RS09935 ENOG4107QW3 Sucrose phosphorylase HUU83_RS09940 ENOG4105WEM extracellular solute-binding protein HUU83_RS09945 ENOG4105HS6 binding-protein-dependent transport systems inner membrane Component HUU83_RS09950 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component HUU83_RS09955 ENOG4107RRD Dehydrogenase HUU83_RS09960 ENOG4107TYA transient receptor potential locus HUU83_RS09965 ENOG4105CK5 oxidoreductase HUU83_RS09970 ENOG4105C71 hydrolase family 65, central catalytic HUU83_RS09975 ENOG4107URF beta-phospho-glucomutase HUU83_RS09980 ENOG4108IJ9 (ABC) transporter HUU83_RS09985 ENOG4107EFV Outer membrane protein G HUU83_RS09990 ENOG4105FKQ transcriptional regulator HUU83_RS09995 ENOG4105CM6 amino acid regulated cytosolic protein HUU83_RS10005 ENOG4108JU8 Transcriptional regulator HUU83_RS10010 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) HUU83_RS10015 ENOG4107S8C mandelate racemase muconate lactonizing HUU83_RS10020 ENOG4105KXI murein peptide amidase A HUU83_RS10030 ENOG4105ENX hydrolase HUU83_RS10035 ENOG4105ENX hydrolase HUU83_RS10040 ENOG4105EQ2 LysR family Transcriptional regulator HUU83_RS10045 ENOG4107QSI ABC, transporter HUU83_RS10050 ENOG4105D64 Mechanosensitive ion channel HUU83_RS10055 ENOG4105S5I Membrane HUU83_RS10060 ENOG4105Q9Y Universal stress protein HUU83_RS10065 ENOG4105DS0 Transcriptional regulator, Crp Fnr family HUU83_RS10070 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) HUU83_RS10075 ENOG4105CFC Transporter HUU83_RS10080 ENOG4107RT5 aminobenzoyl-glutamate utilization protein B HUU83_RS10085 ENOG4105CH2 amidohydrolase HUU83_RS10090 ENOG4106KR7 LysR family Transcriptional regulator HUU83_RS10095 ENOG4108DG9 Smr protein MutS2 HUU83_RS10100 ENOG4105BZU Histidine kinase HUU83_RS10110 ENOG4105C1J atp-dependent rna helicase HUU83_RS10120 ENOG4107R08 Integrase HUU83_RS10125 ENOG4107160 Rac prophage HUU83_RS10130 ENOG41070YT Rac prophage HUU83_RS10135 ENOG4106YAH restriction alleviation and modification enhancement HUU83_RS10140 ENOG4108PNI recT protein HUU83_RS10145 ENOG41076J9 exonuclease VIII HUU83_RS10155 ENOG4107C82 Rac prophage HUU83_RS10190 ENOG4108PM0 it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with DnaB protein and other prepriming proteins DnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N' (By similarity) HUU83_RS10200 ENOG4105C94 Transporter HUU83_RS10215 ENOG4108NH8 Cation transport protein HUU83_RS10220 ENOG4105F27 Major Facilitator HUU83_RS10235 ENOG4105RWQ Protein of unknown function (DUF1364) HUU83_RS10250 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA HUU83_RS10260 ENOG4105QFS Lysis protein S homolog from lambdoid prophage HUU83_RS10265 ENOG4105KUS lysozyme HUU83_RS10275 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) HUU83_RS10280 ENOG4108ES9 ParB domain protein nuclease HUU83_RS10300 ENOG4108X9F tail fiber protein HUU83_RS10305 ENOG4105UZW Tail fiber assembly protein HUU83_RS10325 ENOG4105DEI Mannitol dehydrogenase HUU83_RS10330 ENOG41061EV selenium-binding protein YdfZ HUU83_RS10335 ENOG4107XBN GntR Family Transcriptional Regulator HUU83_RS10340 ENOG4105EMU Dehydrogenase HUU83_RS10345 ENOG4105DGW oligopeptidase A HUU83_RS10350 ENOG4108WTK competence damage-inducible protein HUU83_RS10355 ENOG4108YDI single-species biofilm formation on inanimate substrate HUU83_RS10360 ENOG4105FSR swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria HUU83_RS10370 ENOG4105E5W Transporter HUU83_RS10375 ENOG4108594 Permease of the drug metabolite transporter HUU83_RS10380 ENOG4105FDP GntR family transcriptional regulator HUU83_RS10390 ENOG4105CK1 PTS System HUU83_RS10395 ENOG4105VCP PTS System HUU83_RS10405 ENOG4105CS2 ec 3.2.1.21 HUU83_RS10410 ENOG4106DNR multiple antibiotic resistance protein HUU83_RS10415 ENOG4108XW0 May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF HUU83_RS10420 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes HUU83_RS10440 ENOG4105EGI Transcriptional regulator HUU83_RS10445 ENOG4105C26 Dehydrogenase HUU83_RS10450 ENOG4105CSV Glutaminase HUU83_RS10455 ENOG4105M0C cytoplasmic protein HUU83_RS10460 ENOG4105BZU Histidine kinase HUU83_RS10470 ENOG4105FFC UPF0187 protein HUU83_RS10480 ENOG4105K34 Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the cleavage of phosphorylated 4,5- dihydroxy-2,3-pentanedione (P-DPD) to 2-phosphoglycolic acid (PG) and another three-carbon compound HUU83_RS10505 ENOG4105C2J ABC transporter HUU83_RS10525 ENOG41061P8 Persistence to inhibition of murein or DNA biosynthesis regulatory protein HUU83_RS10530 ENOG4105CAF HipA N-terminal domain protein HUU83_RS10550 ENOG4105CW0 outer membrane usher protein HUU83_RS10555 ENOG4108WDE Fimbrial protein HUU83_RS10560 ENOG4106318 fimbrial-like protein YdeR HUU83_RS10565 ENOG4106PIH fimbrial-like protein ydeQ HUU83_RS10570 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit HUU83_RS10580 ENOG4105Z68 AraC Family Transcriptional Regulator HUU83_RS10585 ENOG4105ENH Sulfatase HUU83_RS10590 ENOG4105C4X radical SAM domain protein HUU83_RS10600 ENOG4105CQ0 ABC transporter HUU83_RS10605 ENOG4105PE1 Receptor HUU83_RS10610 ENOG4107RAN Peptidase, M16 HUU83_RS10615 ENOG4105CVK Glutamate decarboxylase HUU83_RS10620 ENOG4105E5D amino acid HUU83_RS10625 ENOG4105F32 YngK protein HUU83_RS10635 ENOG4105BZU Histidine kinase HUU83_RS10640 ENOG4108UQS dipeptidase HUU83_RS10645 ENOG4105DEF Extracellular solute-binding protein, family 5 HUU83_RS10650 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HUU83_RS10655 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HUU83_RS10660 ENOG4105C3U ABC transporter HUU83_RS10665 ENOG4107H6U ABC transporter HUU83_RS10670 ENOG4108Z9K Osmotically inducible protein HUU83_RS10675 ENOG4105TPS biofilm-dependent modulation protein HUU83_RS10680 ENOG4107AV5 Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein HUU83_RS10690 ENOG4105DQ4 alcohol dehydrogenase HUU83_RS10695 ENOG41084S7 Plasmid maintenance system antidote protein HUU83_RS10700 ENOG4108MG3 formate dehydrogenase HUU83_RS10705 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HUU83_RS10715 ENOG4105RPH Inner membrane protein YddG HUU83_RS10725 ENOG4108UI3 Leucine Rich repeat HUU83_RS10730 ENOG4107QND Nitrite extrusion protein HUU83_RS10735 ENOG4105CRU nitrate reductase, alpha subunit HUU83_RS10740 ENOG4108IUE nitrate reductase beta subunit HUU83_RS10745 ENOG4108NZN Respiratory nitrate reductase 2 delta chain HUU83_RS10750 ENOG4105D0D Nitrate reductase 2, gamma subunit HUU83_RS10755 ENOG4105JAB phenazine biosynthesis protein, phzf family HUU83_RS10760 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase HUU83_RS10765 ENOG4108MEJ flavin reductase domain protein HUU83_RS10800 ENOG410600T transposase HUU83_RS10830 ENOG4105CNA YD repeat protein HUU83_RS10835 ENOG4105CNA YD repeat protein HUU83_RS10840 ENOG4105CS6 Rhs element vgr protein HUU83_RS10850 ENOG4108N27 Glutathione S-transferase HUU83_RS10855 ENOG4105C85 amino acid HUU83_RS10860 ENOG4108NS2 receptor HUU83_RS10865 ENOG4105CHB tonB-dependent Receptor HUU83_RS10870 ENOG4108WYP Transcriptional regulator HUU83_RS10875 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein HUU83_RS10880 ENOG4108Z7F N-acetyltransferase HUU83_RS10885 ENOG4108T9Y Inner membrane protein ydcZ HUU83_RS10890 ENOG4105R71 cytoplasmic protein HUU83_RS10895 ENOG410654E Membrane HUU83_RS10915 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component HUU83_RS10920 ENOG4105D81 ABC transporter, permease HUU83_RS10925 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) HUU83_RS10930 ENOG4107TYH extracellular solute-binding protein family 1 HUU83_RS10935 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family HUU83_RS10940 ENOG4105PF0 Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin HUU83_RS10950 ENOG4105RR0 Protein of unknown function (DUF2554) HUU83_RS10955 ENOG4105CFP Peptidase U32 HUU83_RS10960 ENOG4108JCI Transcriptional regulator HUU83_RS10965 ENOG4105DKK Benzoate HUU83_RS10970 ENOG4105D7V transposase HUU83_RS10980 ENOG4108KKZ (LipO)protein HUU83_RS10985 ENOG41088CC tellurite resistance protein tehB HUU83_RS10990 ENOG4108NKP c4-dicarboxylate transporter malic acid transport protein HUU83_RS10995 ENOG4107WE3 acetyltransferase YdcK HUU83_RS11000 ENOG4108Z9I -acetyltransferase HUU83_RS11005 ENOG4105Z2P Protein of unknown function (DUF465) HUU83_RS11015 ENOG4105E32 cytoplasmic protein HUU83_RS11020 ENOG4105DDW LysR family Transcriptional regulator HUU83_RS11025 ENOG4105C8Q Methyl-accepting chemotaxis HUU83_RS11030 ENOG4107NK6 Hok/gef family HUU83_RS11035 ENOG4105UPP uncharacterized protein ydcA HUU83_RS11040 ENOG4105CPW cytochrome b561 HUU83_RS11045 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase HUU83_RS11050 ENOG4105C26 Dehydrogenase HUU83_RS11055 ENOG4107DB1 DUF218 domain HUU83_RS11060 ENOG4105CQ7 ATP-dependent helicase HUU83_RS11070 ENOG41077RS Phosphatase HUU83_RS11075 ENOG4105E8V Alpha Beta Hydrolase Fold protein HUU83_RS11080 ENOG4108HPI phosphatidate Cytidylyltransferase HUU83_RS11085 ENOG4108UMZ Cdp-alcohol phosphatidyltransferase HUU83_RS11095 ENOG4107S5I aldo keto reductase HUU83_RS11100 ENOG4108Z0R Transferase HUU83_RS11105 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein HUU83_RS11110 ENOG4105DZS Phenylacetate-CoA ligase HUU83_RS11115 ENOG4105CHU acetyl-coa acetyltransferase HUU83_RS11120 ENOG4108ZJI phenylacetic acid degradation protein HUU83_RS11125 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase HUU83_RS11130 ENOG4108UKI Enoyl-CoA hydratase HUU83_RS11135 ENOG4105E39 Enoyl-CoA hydratase HUU83_RS11140 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) HUU83_RS11145 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit HUU83_RS11150 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit HUU83_RS11155 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit HUU83_RS11160 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit HUU83_RS11165 ENOG4105DXM phenylacetic acid degradation protein HUU83_RS11170 ENOG4105F11 amine oxidase HUU83_RS11175 ENOG4105C26 Dehydrogenase HUU83_RS11180 ENOG4108WFR AraC Family Transcriptional Regulator HUU83_RS11185 ENOG4105WXT Conserved Protein HUU83_RS11190 ENOG410689M (LipO)protein HUU83_RS11195 ENOG4107H52 Dicarboxylate transport HUU83_RS11200 ENOG4105C5I Dehydrogenase HUU83_RS11205 ENOG41090X5 Heat shock protein hslJ HUU83_RS11210 ENOG4105IKK cytoplasmic protein HUU83_RS11215 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) HUU83_RS11220 ENOG4105FCK Membrane HUU83_RS11225 ENOG4108RW8 Universal stress protein F HUU83_RS11235 ENOG4105W3V DNA-binding, transcriptional regulator HUU83_RS11240 ENOG4105MN3 Resolvase HUU83_RS11245 ENOG4105UZW Tail fiber assembly protein HUU83_RS11250 ENOG4108X9F tail fiber protein HUU83_RS11325 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) HUU83_RS11375 ENOG4105QFS Lysis protein S homolog from lambdoid prophage HUU83_RS11380 ENOG4105HGD Antitermination protein HUU83_RS11385 ENOG4105KSK (crossover) junction endodeoxyribonuclease HUU83_RS11390 ENOG4108MXB Protein of unknown function (DUF968) HUU83_RS11460 ENOG41087BU transcriptional repressor DicA HUU83_RS11480 ENOG4106G8A Qin prophage HUU83_RS11495 ENOG4107R08 Integrase HUU83_RS11505 ENOG4105CPQ Dehydrogenase HUU83_RS11510 ENOG4105CXK mandelate racemase muconate lactonizing HUU83_RS11525 ENOG4108MK9 spermidine N(1)-acetyltransferase HUU83_RS11530 ENOG4105D69 UPF0257 lipoprotein ynfC HUU83_RS11535 ENOG4105KBG Protein of unknown function (DUF1161) HUU83_RS11540 ENOG4107QY8 reductase HUU83_RS11545 ENOG4105C3J Cysteine desulfurase HUU83_RS11550 ENOG4105QAX Iron-sulfur HUU83_RS11555 ENOG4107KGK dmso reductase anchor subunit HUU83_RS11560 ENOG4108NEM leader-binding protein dmsD HUU83_RS11570 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) HUU83_RS11575 ENOG4105DAG ROK family HUU83_RS11580 ENOG4106NZI LysR family Transcriptional regulator HUU83_RS11585 ENOG4105D94 Major Facilitator Superfamily HUU83_RS11600 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap HUU83_RS11615 ENOG4105DSF transport protein HUU83_RS11620 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) HUU83_RS11625 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) HUU83_RS11630 ENOG4105C5D exported protein HUU83_RS11635 ENOG4105D5Q Arginine ornithine antiporter HUU83_RS11645 ENOG4105RA2 Membrane HUU83_RS11650 ENOG4107EXC regulatoR HUU83_RS11655 ENOG4105JJR Histidine kinase HUU83_RS11665 ENOG4105C9Q fumarate hydratase class II HUU83_RS11670 ENOG4107GFK fumarate HUU83_RS11675 ENOG4105EIP mannose-6-phosphate isomerase HUU83_RS11680 ENOG4106J39 exported protein HUU83_RS11685 ENOG4108QNI outer membrane porin protein HUU83_RS11690 ENOG4105CT4 transporter HUU83_RS11700 ENOG4105XEA Tetr family transcriptional regulator HUU83_RS11705 ENOG4107ZQV short-chain dehydrogenase reductase HUU83_RS11710 ENOG4107P2S Transcriptional regulator HUU83_RS11715 ENOG4105CI1 PTS System HUU83_RS11720 ENOG4105C87 Aminotransferase class I and II HUU83_RS11730 ENOG4105D9R oxidoreductase HUU83_RS11735 ENOG4106C6R beta-lactam resistance protein HUU83_RS11740 ENOG4105QZ5 OriC-binding nucleoid-associated protein HUU83_RS11745 ENOG4105M9B inner membrane protein ydgK HUU83_RS11770 ENOG4108UQQ Electron transport complex HUU83_RS11780 ENOG4105CSM endonuclease III HUU83_RS11785 ENOG4105DUX Transporter HUU83_RS11790 ENOG4108K3A Glutathione S-transferase HUU83_RS11795 ENOG4107XGF functions in a salvage pathway. Uses pyridoxamine (By similarity) HUU83_RS11810 ENOG410642K Lysozyme inhibitor HUU83_RS11820 ENOG4108XTF Outer Membrane Lipoprotein HUU83_RS11835 ENOG4105Y49 secretion protein, HlyD family HUU83_RS11840 ENOG4105DSW Fusaric acid resistance protein HUU83_RS11845 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) HUU83_RS11850 ENOG4107RGM aldo keto reductase HUU83_RS11855 ENOG4105XZD Fe-S protein HUU83_RS11860 ENOG4108WUH Transcriptional regulator, TetR family HUU83_RS11865 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase HUU83_RS11870 ENOG4108UYE Lactoylglutathione lyase HUU83_RS11880 ENOG4107QRT dEAD DEAH box helicase HUU83_RS11885 ENOG4105M2J Glutaredoxin HUU83_RS11890 ENOG4105K4H Nlp p60 protein HUU83_RS11895 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) HUU83_RS11900 ENOG4105F27 Major Facilitator HUU83_RS11915 ENOG4105F52 Transcriptional regulator HUU83_RS11920 ENOG4105CZQ inner membrane transport protein YdhC HUU83_RS11925 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase HUU83_RS11930 ENOG4108R6K riboflavin synthase, subunit alpha HUU83_RS11955 ENOG4105N0V mono-oxygenase ydhR HUU83_RS11960 ENOG4108KTU conserved protein with FAD NAD(P)-binding domain HUU83_RS11965 ENOG4108Y7C Conserved Protein HUU83_RS11970 ENOG4108NWD Cytochrome HUU83_RS11975 ENOG4108393 oxidoreductase Fe-S subunit HUU83_RS11980 ENOG4105JVW HUU83_RS11985 ENOG4105WE2 aldehyde ferredoxin oxidoreductase HUU83_RS11990 ENOG4108PU5 4fe-4S ferredoxin, iron-sulfur binding domain protein HUU83_RS11995 ENOG4105RFR Protein of unknown function (DUF2767) HUU83_RS12000 ENOG4105CA9 Pyruvate kinase HUU83_RS12005 ENOG4105KMX major outer membrane lipoprotein HUU83_RS12010 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein HUU83_RS12025 ENOG4105JRK feS assembly protein SufD HUU83_RS12030 ENOG4105C3K feS assembly ATPase SufC HUU83_RS12035 ENOG4105DIW FeS assembly protein SUFB HUU83_RS12040 ENOG4108Z4V iron-sulfur cluster assembly HUU83_RS12045 ENOG410671Z uncharacterized protein ydiH HUU83_RS12050 ENOG4105KA0 thioesterase Superfamily protein HUU83_RS12055 ENOG4105CQB FAD linked oxidase domain protein HUU83_RS12060 ENOG4105IPI Membrane HUU83_RS12070 ENOG4105SUA Ydil protein HUU83_RS12075 ENOG4105EMV Major Facilitator HUU83_RS12080 ENOG4105EMV Major Facilitator HUU83_RS12095 ENOG4108IIG CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) HUU83_RS12100 ENOG4105C1G acyl-Coa dehydrogenase HUU83_RS12105 ENOG4105W4W Transcriptional regulator HUU83_RS12110 ENOG4105CV7 Electron transfer flavoprotein HUU83_RS12115 ENOG4105C10 Electron transfer flavoprotein HUU83_RS12120 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase HUU83_RS12125 ENOG41090P5 ferredoxin-like protein HUU83_RS12130 ENOG4105CEY Amp-dependent synthetase and ligase HUU83_RS12135 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) HUU83_RS12145 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) HUU83_RS12160 ENOG4108TC0 Diguanylate phosphodiesterase HUU83_RS12165 ENOG4108QBX (LipO)protein HUU83_RS12175 ENOG4108V06 Glutathione peroxidase HUU83_RS12210 ENOG41082NX 50s ribosomal protein l35 HUU83_RS12215 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) HUU83_RS12235 ENOG4108NE3 Salt-induced outer membrane protein HUU83_RS12240 ENOG4105DE4 1-phosphofructokinase HUU83_RS12245 ENOG4105P10 Uncharacterized protein ydiZ HUU83_RS12255 ENOG4107PN8 YfeABCD locus regulator HUU83_RS12260 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 HUU83_RS12265 ENOG4107K5X Membrane-bound metal-dependent hydrolase HUU83_RS12270 ENOG4108ETY sodium dicarboxylate symporter HUU83_RS12290 ENOG4105CH6 catalase HUU83_RS12305 ENOG4105F8D glycoside hydrolase family 4 HUU83_RS12310 ENOG4105EZV Transcriptional regulator HUU83_RS12315 ENOG4105VCP PTS System HUU83_RS12320 ENOG4105CK1 PTS System HUU83_RS12325 ENOG4105VZJ PTS System HUU83_RS12330 ENOG4105KKI DNA-binding transcriptional activator OsmE HUU83_RS12340 ENOG4105DKD Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity) HUU83_RS12350 ENOG4108SPG Periplasmic Protein HUU83_RS12380 ENOG4105CGK Exodeoxyribonuclease III HUU83_RS12385 ENOG4108RSN SNARE associated Golgi HUU83_RS12390 ENOG4108KCW iron-sulfur cluster binding HUU83_RS12395 ENOG4108N5C SNARE associated Golgi protein-related protein HUU83_RS12400 ENOG4107ZN8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) HUU83_RS12405 ENOG4105VNH ABC transporter solute-binding protein HUU83_RS12410 ENOG4105CXZ ABC transporter, permease HUU83_RS12415 ENOG4108VGW abc transporter atp-binding protein HUU83_RS12420 ENOG4107RM6 sulfurtransferase HUU83_RS12425 ENOG4108T9J Cdp-alcohol phosphatidyltransferase HUU83_RS12430 ENOG4105M6F mutator MutT protein HUU83_RS12435 ENOG4105MTM Protein of unknown function (DUF1496) HUU83_RS12440 ENOG4105D82 Glutamate dehydrogenase HUU83_RS12445 ENOG41065FB inner membrane protein ynji HUU83_RS12450 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) HUU83_RS12455 ENOG4105D4F Synthesizes selenophosphate from selenide and ATP (By similarity) HUU83_RS12460 ENOG41069NU Nitroreductase HUU83_RS12465 ENOG4105D07 Signal peptide peptidase, SppA HUU83_RS12470 ENOG4105HDK L-asparaginase HUU83_RS12475 ENOG4108RWI nicotinamidase HUU83_RS12480 ENOG4105VUT cytoplasmic protein HUU83_RS12490 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase HUU83_RS12495 ENOG4105DSB aldose 1-epimerase HUU83_RS12500 ENOG4105CV8 reductase HUU83_RS12505 ENOG4105GNX MltA-interacting MipA family protein HUU83_RS12510 ENOG4105CYN Serine protein kinase HUU83_RS12520 ENOG4106KTS Inner membrane protein yeaI HUU83_RS12525 ENOG4108KHP Diguanylate cyclase HUU83_RS12530 ENOG4108KXH Ybak prolyl-tRNA synthetase associated HUU83_RS12545 ENOG4105R1U AraC Family Transcriptional Regulator HUU83_RS12550 ENOG4105DJ2 Major Facilitator Superfamily HUU83_RS12555 ENOG4105K78 MarR family Transcriptional regulator HUU83_RS12560 ENOG4105UCG Domain of unknown function (DUF333) HUU83_RS12565 ENOG410620I Diguanylate cyclase HUU83_RS12570 ENOG4106G4W HUU83_RS12580 ENOG4105Y3U Transglycosylase-associated protein HUU83_RS12585 ENOG4105D7V transposase HUU83_RS12590 ENOG4108RS6 transposase HUU83_RS12595 ENOG4105YP6 Domain of unknown function (DUF1869) HUU83_RS12600 ENOG4108YS1 cytoplasmic protein HUU83_RS12610 ENOG4105EJC lysr family transcriptional regulator HUU83_RS12615 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) HUU83_RS12620 ENOG4105C94 Transporter HUU83_RS12625 ENOG4105DVW rieske (2Fe-2S) HUU83_RS12630 ENOG4105E3J oxidoreductase HUU83_RS12635 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) HUU83_RS12640 ENOG4105CEY Amp-dependent synthetase and ligase HUU83_RS12645 ENOG4105Y4Z Outer Membrane Lipoprotein HUU83_RS12650 ENOG41072GX Peptidase M22 Glycoprotease HUU83_RS12655 ENOG4105DVT helicase HUU83_RS12660 ENOG4105M4H endoribonuclease L-psp HUU83_RS12665 ENOG4105V2F Uncharacterized protein yoac HUU83_RS12675 ENOG4105CRQ synthase (Component I) HUU83_RS12685 ENOG4105EJQ L-serine dehydratase HUU83_RS12690 ENOG4107XTP (EAL) domain protein HUU83_RS12695 ENOG4105EE5 Membrane protein terC HUU83_RS12700 ENOG4105DAS pts system HUU83_RS12705 ENOG4105ETZ PTS System HUU83_RS12710 ENOG4105F3R pts system mannose fructose sorbose family iid HUU83_RS12725 ENOG4105DHI Methyltransferase HUU83_RS12740 ENOG4105Q3Y exported protein HUU83_RS12750 ENOG4105TIK HUU83_RS12755 ENOG4105J4Q Transcriptional regulator HUU83_RS12760 ENOG4105C0R drug resistance transporter emrb qaca subfamily HUU83_RS12770 ENOG4105CN1 protease HUU83_RS12780 ENOG4108ZGC gaf domain protein HUU83_RS12785 ENOG4105H2K paraquat-inducible protein a HUU83_RS12790 ENOG4105DY2 Paraquat-inducible protein b HUU83_RS12800 ENOG4105WT8 Protein of unknown function (DUF1480) HUU83_RS12805 ENOG4105UVW uncharacterized protein yebW HUU83_RS12810 ENOG4108R1E Serine threonine protein phosphatase 1 HUU83_RS12815 ENOG4105NKT exported protein HUU83_RS12820 ENOG4108PNC copper resistance HUU83_RS12825 ENOG4105FXM Copper resistance protein HUU83_RS12830 ENOG4105MPK DNA polymerase III subunit theta HUU83_RS12835 ENOG4108YGA nitrilase cyanide hydratase and apolipoprotein n-acyltransferase HUU83_RS12840 ENOG4105UMD exodeoxyribonuclease X HUU83_RS12845 ENOG4105CUG Oligopeptidase b HUU83_RS12850 ENOG4108Q2J Inner membrane protein YebE HUU83_RS12860 ENOG4105X2V dna damage-inducible protein HUU83_RS12870 ENOG4108UHU Aldolase HUU83_RS12875 ENOG4105C01 Dihydroxy-acid dehydratase HUU83_RS12880 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase HUU83_RS12885 ENOG4106KNT transcriptional regulator HUU83_RS12890 ENOG4105CA9 Pyruvate kinase HUU83_RS12895 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase HUU83_RS12900 ENOG4105DR5 peptidase HUU83_RS12905 ENOG4105NXV High-affinity zinc uptake system protein HUU83_RS12915 ENOG4105FAV ABC, transporter HUU83_RS12935 ENOG4107S01 Repressor protein MetJ HUU83_RS12945 ENOG4105CDY transcriptional regulatory protein HUU83_RS12950 ENOG4108TIT dATP pyrophosphohydrolase HUU83_RS12960 ENOG4105D3W isochorismatase HUU83_RS12965 ENOG41081XQ Conserved Protein HUU83_RS12970 ENOG4105WJG Glutathione HUU83_RS12985 ENOG4107QY8 reductase HUU83_RS12990 ENOG4105CUW cytochrome C-TYPE protein HUU83_RS13000 ENOG4106ZCM YecM protein HUU83_RS13015 ENOG4105W13 flagellar protein HUU83_RS13020 ENOG4105D7B Flagellar biosynthesis protein flha HUU83_RS13025 ENOG4105D00 flagellar biosynthetic protein flhB HUU83_RS13030 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) HUU83_RS13035 ENOG4108VYJ response regulator receiver protein HUU83_RS13040 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) HUU83_RS13045 ENOG4105BZU Histidine kinase HUU83_RS13050 ENOG4105C8Q Methyl-accepting chemotaxis HUU83_RS13055 ENOG4105C8Q Methyl-accepting chemotaxis HUU83_RS13060 ENOG4108V3W Chemotaxis protein, CheW HUU83_RS13065 ENOG4105CBS Chea signal transduction histidine kinase HUU83_RS13070 ENOG4105ER2 Ompa motb domain protein HUU83_RS13075 ENOG4107RD7 Flagellar Motor Protein, MotA HUU83_RS13080 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region HUU83_RS13090 ENOG4108VA4 Universal stress protein HUU83_RS13100 ENOG4108K4C ec 3.1.3.12 HUU83_RS13105 ENOG4105CNN ABC, transporter HUU83_RS13110 ENOG4105C2J ABC transporter HUU83_RS13115 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator HUU83_RS13120 ENOG4108UEC Ferritin-like protein HUU83_RS13125 ENOG4105N4N Protein of unknown function (DUF2766) HUU83_RS13135 ENOG4105P23 (LipO)protein HUU83_RS13140 ENOG41090A1 ferritin HUU83_RS13145 ENOG4105VVZ metal-binding protein HUU83_RS13150 ENOG4105E0U tyrosine-specific transport protein HUU83_RS13155 ENOG4106RHG Yeca family HUU83_RS13185 ENOG4105WH1 Two component transcriptional regulator luxr family HUU83_RS13195 ENOG4105XVG cytoplasmic protein HUU83_RS13200 ENOG4105VJY transcriptional regulator HUU83_RS13205 ENOG4105CDA abc transporter atp-binding protein HUU83_RS13210 ENOG4105E5Q amino acid AbC transporter HUU83_RS13220 ENOG4105EAB amino acid AbC transporter HUU83_RS13225 ENOG4108M9K flagella biosynthesis protein FliZ HUU83_RS13230 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HUU83_RS13240 ENOG4105DTS flagellar hook-associated HUU83_RS13245 ENOG4105MQ3 flagellar protein FliS HUU83_RS13250 ENOG4105YXP it directly binds FlhC, thus inhibiting the binding of the FlhC FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus (By similarity) HUU83_RS13255 ENOG4105E5K Alpha-amylase HUU83_RS13260 ENOG4108W9D (LipO)protein HUU83_RS13265 ENOG41066VF YeeE YedE family protein HUU83_RS13275 ENOG4108RAV Conserved protein HUU83_RS13280 ENOG4105D7V transposase HUU83_RS13285 ENOG4108RS6 transposase HUU83_RS13290 ENOG4108UQN AraC family transcriptional regulator HUU83_RS13295 ENOG4108V1U phospholipid-binding protein HUU83_RS13300 ENOG410814C multidrug resistance protein HUU83_RS13305 ENOG4105VQ0 flagellar hook-basal body complex protein fliE HUU83_RS13310 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) HUU83_RS13315 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) HUU83_RS13320 ENOG41090PJ Flagellar assembly protein HUU83_RS13325 ENOG4108JIR Flagellum-specific ATP synthase HUU83_RS13330 ENOG4105GSA Flagellar export protein flij HUU83_RS13335 ENOG4105WF4 Flagellar hook-length control protein HUU83_RS13340 ENOG4107ZI8 flagellar basal body-associated protein flil HUU83_RS13345 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) HUU83_RS13350 ENOG4105DD5 Flagellar motor switch protein HUU83_RS13355 ENOG4105K0P flagellar biosynthesis protein HUU83_RS13360 ENOG4105CN7 Flagellar biosynthetic protein FliP HUU83_RS13370 ENOG4105D19 Role in flagellar biosynthesis (By similarity) HUU83_RS13375 ENOG4107TKS colanic acid capsular biosynthesis activation protein A HUU83_RS13385 ENOG4105YX3 cellular response to acidity HUU83_RS13400 ENOG4105VNZ cytoplasmic protein HUU83_RS13405 ENOG4105CKW Inner membrane protein yedI HUU83_RS13410 ENOG4105FDR Membrane HUU83_RS13415 ENOG41090BB DNA mismatch endonuclease (vsr) HUU83_RS13420 ENOG4105DVF Cytosine-specific methyltransferase HUU83_RS13425 ENOG4105EST Metal Dependent Phosphohydrolase HUU83_RS13430 ENOG4105Y0K Inner membrane protein YedR HUU83_RS13435 ENOG4105ZIT Porin Gram-negative type HUU83_RS13440 ENOG4105TMR Functions as a holding molecular chaperone (holdase) which stabilizes unfolding intermediates and rapidly releases them in an active form once stress has abated. Plays an important role in protecting cells from severe heat shock and starvation, as well as in acid resistance of stationary-phase cells. It catalyzes the conversion of methylglyoxal (MG) to D-lactate in a single glutathione (GSH)-independent step (By similarity) HUU83_RS13445 ENOG4107ZY3 Histidine kinase HUU83_RS13450 ENOG4105CK6 Two component transcriptional regulator (Winged helix family HUU83_RS13455 ENOG4105VT2 5-hydroxyisourate hydrolase HUU83_RS13470 ENOG4108MEK Metal-binding protein YodA HUU83_RS13475 ENOG4108VKM cytochrome b561 HUU83_RS13485 ENOG4105EXZ Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity) HUU83_RS13495 ENOG4105TNG K13735 adhesin invasin HUU83_RS13505 ENOG4105CSH Transporter HUU83_RS13510 ENOG4105FYV Amp nucleosidase HUU83_RS13515 ENOG4105CDY transcriptional regulatory protein HUU83_RS13525 ENOG4105UQX Mate efflux family protein HUU83_RS13535 ENOG4107R11 Transcriptional regulator HUU83_RS13540 ENOG4106P55 Transcriptional regulator HUU83_RS13550 ENOG4108PXI ErfK YbiS YcfS YnhG HUU83_RS13555 ENOG4105CUP Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity) HUU83_RS13560 ENOG4108UHF Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity) HUU83_RS13565 ENOG4108YZT Adenosylcobinamide kinase HUU83_RS13580 ENOG41080QX K07048 phosphotriesterase-related protein HUU83_RS13630 ENOG4108P8R HUU83_RS13640 ENOG4105F4K antigen 43 HUU83_RS13645 ENOG4108PZQ Inner membrane protein YeeR HUU83_RS13655 ENOG4105E5H Transposase HUU83_RS13660 ENOG4108YXQ IS66 Orf2 family protein HUU83_RS13675 ENOG4106H6R UPF0380 protein HUU83_RS13680 ENOG4105MFG Antirestriction protein HUU83_RS13685 ENOG4108YGG dna repair protein HUU83_RS13695 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles HUU83_RS13730 ENOG4105DR8 Membrane HUU83_RS13750 ENOG4105DZ1 carboxypeptidase HUU83_RS13755 ENOG4105CJB Exodeoxyribonuclease I HUU83_RS13770 ENOG4105CUB amino acid HUU83_RS13780 ENOG4105EQ1 Transcriptional regulator HUU83_RS13785 ENOG4107SRH Nad-dependent epimerase dehydratase HUU83_RS13790 ENOG4105KRQ Addiction module toxin, Txe YoeB family HUU83_RS13795 ENOG4105VTW prevent-host-death family HUU83_RS13820 ENOG4105ECC imidazole-glycerol-phosphate dehydratase HUU83_RS13825 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) HUU83_RS13845 ENOG4108KPN Confers a modal distribution of chain length on the O- antigen component of lipopolysaccharide (LPS). Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules, with a modal value of 13 (in strain O111 M92) and of 17 (in strain K12) HUU83_RS13850 ENOG4105C6Y Udp-glucose 6-dehydrogenase HUU83_RS13855 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) HUU83_RS13895 ENOG4107QKV phosphomannomutase HUU83_RS13900 ENOG4105CJT Mannose-1-phosphate guanylyltransferase HUU83_RS13905 ENOG4105E2K Glycosyl transferase (Group 1 HUU83_RS13915 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase HUU83_RS13920 ENOG4105G1A colanic acid biosynthesis protein HUU83_RS13925 ENOG4107T8Q Glycosyl transferase (Group 1 HUU83_RS13930 ENOG4105C74 pyruvyl transferase HUU83_RS13935 ENOG4105PSV Polysaccharide Biosynthesis Protein HUU83_RS13940 ENOG4105D3Q Sugar transferase HUU83_RS13945 ENOG4107QKV phosphomannomutase HUU83_RS13950 ENOG4105CJT Mannose-1-phosphate guanylyltransferase HUU83_RS13955 ENOG4106CD9 glycosyl transferase group 1 HUU83_RS13960 ENOG4105FGF GDP-mannose mannosyl hydrolase HUU83_RS13965 ENOG4105C30 Nad-dependent epimerase dehydratase HUU83_RS13970 ENOG4105C0K Gdp-mannose 4,6-dehydratase HUU83_RS13975 ENOG4108Z90 colanic acid biosynthesis acetyltransferase wcaF HUU83_RS13980 ENOG4105ECJ Glycosyl Transferase HUU83_RS13985 ENOG4108NYJ Colanic acid HUU83_RS13990 ENOG4107RXY Glycosyl transferase HUU83_RS13995 ENOG41068PY Colanic acid biosynthesis acetyltransferase wcaB HUU83_RS14000 ENOG41090RK glycosyl transferase HUU83_RS14005 ENOG4105D75 Capsular exopolysaccharide family HUU83_RS14010 ENOG4105KJF protein tyrosine phosphatase HUU83_RS14015 ENOG4105DAY polysaccharide export protein HUU83_RS14025 ENOG4105EE5 Membrane protein terC HUU83_RS14030 ENOG4108GAE asmA family HUU83_RS14040 ENOG4105DBI uridine monophosphokinase HUU83_RS14050 ENOG4105D03 DNA-3-methyladenine glycosylase II HUU83_RS14055 ENOG4105R8A Heat shock protein HUU83_RS14060 ENOG4106E1W protein with protein kinase and helix-hairpin-helix DNA-binding HUU83_RS14065 ENOG4105UM3 Inherit from NOG: serine threonine phosphoprotein phosphatase HUU83_RS14070 ENOG4108M24 von Willebrand factor, type A HUU83_RS14090 ENOG4105BZS acriflavin resistance protein HUU83_RS14105 ENOG4105EB3 Histidine kinase HUU83_RS14110 ENOG4105E3W Two component transcriptional regulator (Winged helix family HUU83_RS14115 ENOG4105KWI UPF0339 protein HUU83_RS14120 ENOG4105X54 addiction module antidote protein HUU83_RS14130 ENOG4105CFP Peptidase U32 HUU83_RS14135 ENOG41076Z6 Uncharacterized protein yegR HUU83_RS14150 ENOG4107WTH Galactitol-1-phosphate dehydrogenase HUU83_RS14155 ENOG4105DT3 PTS system, galactitol-specific IIc component HUU83_RS14160 ENOG41090UW PTS System HUU83_RS14165 ENOG41082GB PTS system galactitol-specific transporter subunit IIA HUU83_RS14180 ENOG4105EIE fructose-bisphosphate aldolase HUU83_RS14185 ENOG4105EAA nucleoside HUU83_RS14190 ENOG4108KD5 ADP-ribosylation crystallin J1 HUU83_RS14195 ENOG4108TFM Kinase, PfkB family HUU83_RS14200 ENOG4105FDP GntR family transcriptional regulator HUU83_RS14205 ENOG4108UQ1 hydrolase, family 25 HUU83_RS14210 ENOG4105DWF phosphomethylpyrimidine kinase HUU83_RS14230 ENOG4108Z1S Influences nickel and cobalt homeostasis. May act by modulating RcnA-mediated export of these ions to avoid excess efflux. Not involved in nickel import and does not bind nickel or cobalt ions directly HUU83_RS14235 ENOG410662B Type-1 fimbrial protein HUU83_RS14240 ENOG4105CW0 outer membrane usher protein HUU83_RS14245 ENOG4108MQF Chaperone HUU83_RS14250 ENOG41063W2 Fimbrial protein HUU83_RS14255 ENOG41067AK Protein of unknown function (DUF2574) HUU83_RS14260 ENOG4105D1F ATP-binding protein HUU83_RS14270 ENOG4108KDT Molybdate metabolism regulator HUU83_RS14275 ENOG4108KDT Molybdate metabolism regulator HUU83_RS14280 ENOG4108KDT Molybdate metabolism regulator HUU83_RS14290 ENOG4105KKX ATPase associated with various cellular activities aaa_5 HUU83_RS14295 ENOG4105RD5 HUU83_RS14300 ENOG4105DEG Vwa containing coxe family protein HUU83_RS14305 ENOG410903U zinc ion binding HUU83_RS14310 ENOG4108YCW (LipO)protein HUU83_RS14315 ENOG4108W15 Protein of unknown function (DUF1456) HUU83_RS14320 ENOG4108NEV two component transcriptional regulator, LytTR family HUU83_RS14325 ENOG4108HRK Histidine kinase HUU83_RS14330 ENOG4108XDN Transcriptional regulator HUU83_RS14340 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component HUU83_RS14345 ENOG4108IJ8 ABC transporter HUU83_RS14350 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component HUU83_RS14355 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system HUU83_RS14360 ENOG4107QK4 glycoside hydrolase, family 3 domain protein HUU83_RS14365 ENOG4105CXG d-lactate dehydrogenase HUU83_RS14370 ENOG41061WM D-Alanyl-D-Alanine HUU83_RS14375 ENOG41069YE inner membrane protein yohC HUU83_RS14380 ENOG4105KHU inner membrane protein YohD HUU83_RS14385 ENOG4105H9W Short-chain dehydrogenase reductase Sdr HUU83_RS14390 ENOG4105ETP RND efflux system, outer membrane lipoprotein HUU83_RS14400 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) HUU83_RS14410 ENOG41067MG lrgb family HUU83_RS14420 ENOG4107GZ4 SanA protein HUU83_RS14425 ENOG4105Y9N Membrane HUU83_RS14430 ENOG4105BZ8 glutamate synthase HUU83_RS14435 ENOG4107SJI Dehydrogenase HUU83_RS14440 ENOG4108HWV )-transporter HUU83_RS14445 ENOG4105C2J ABC transporter HUU83_RS14450 ENOG4105EMA Periplasmic binding protein LacI transcriptional regulator HUU83_RS14455 ENOG41060NJ transcriptional regulator HUU83_RS14460 ENOG4105DHF Membrane HUU83_RS14475 ENOG4105D05 Receptor HUU83_RS14480 ENOG4108IQI permease HUU83_RS14485 ENOG4105DUM transcriptional regulator, lysR family HUU83_RS14490 ENOG4105HMI Membrane HUU83_RS14500 ENOG4105DD7 kinase (PfkB family HUU83_RS14505 ENOG4105D9N nucleoside HUU83_RS14515 ENOG4108Y4K DNA-binding transcriptional activator HUU83_RS14520 ENOG4105D9N nucleoside HUU83_RS14525 ENOG4105D53 Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity) HUU83_RS14530 ENOG4105DD7 kinase (PfkB family HUU83_RS14535 ENOG4105DM4 PTS System HUU83_RS14540 ENOG4105DE4 1-phosphofructokinase HUU83_RS14545 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein HUU83_RS14550 ENOG4105S8Q sugar efflux transporter HUU83_RS14555 ENOG4105KRS Proteinase inhibitor HUU83_RS14565 ENOG4105DEI Mannitol dehydrogenase HUU83_RS14570 ENOG4105CKI cobalamin synthesis protein HUU83_RS14575 ENOG41076MN Phosphoesterase, PA-phosphatase related HUU83_RS14580 ENOG4107TT5 NLP P60 protein HUU83_RS14585 ENOG4105CXC rtn protein HUU83_RS14590 ENOG4105E43 Extracellular solute-binding protein, family 5 HUU83_RS14595 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component HUU83_RS14600 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component HUU83_RS14605 ENOG4108JQ5 ABC transporter HUU83_RS14610 ENOG4105HG6 HUU83_RS14615 ENOG4105C2C drug resistance transporter, Bcr CflA HUU83_RS14620 ENOG4105I08 Pseudouridine synthase HUU83_RS14625 ENOG4105CFI type iii restriction protein res subunit HUU83_RS14645 ENOG4105E68 Sulfatase HUU83_RS14660 ENOG4105WH1 Two component transcriptional regulator luxr family HUU83_RS14665 ENOG4105KWW Biogenesis protein HUU83_RS14670 ENOG4107QX9 Thiol disulfide interChange protein HUU83_RS14675 ENOG4105DA4 cytochrome c-type biogenesis protein HUU83_RS14685 ENOG4105X3C heme exporter protein HUU83_RS14690 ENOG41060IM Heme exporter protein HUU83_RS14695 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) HUU83_RS14700 ENOG4107EV4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity) HUU83_RS14705 ENOG4105CUW cytochrome C-TYPE protein HUU83_RS14710 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) HUU83_RS14715 ENOG4105GXZ Ferredoxin-type protein NapH HUU83_RS14720 ENOG4108BGM Quinol dehydrogenase periplasmic component HUU83_RS14730 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase HUU83_RS14735 ENOG4108ZNS ferredoxin-type protein NapF HUU83_RS14755 ENOG4105IBP Cyclic peptide transporter HUU83_RS14760 ENOG4105CF1 Alkylated DNA repair protein HUU83_RS14765 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) HUU83_RS14770 ENOG4105CJ2 (LipO)protein HUU83_RS14775 ENOG4105FCK Membrane HUU83_RS14780 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC HUU83_RS14785 ENOG41068CG regulatoR HUU83_RS14790 ENOG4105BZU Histidine kinase HUU83_RS14795 ENOG4105EDV vault protein HUU83_RS14800 ENOG41081SK signal peptide protein HUU83_RS14805 ENOG4107S52 alpha-2-macroglobulin domain protein HUU83_RS14810 ENOG4108QJJ Protein of unknown function (DUF1175) HUU83_RS14815 ENOG4107FKF Uncharacterized protein conserved in bacteria (DUF2138) HUU83_RS14820 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HUU83_RS14830 ENOG4107GHC outer membrane autotransporter HUU83_RS14835 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HUU83_RS14840 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HUU83_RS14845 ENOG4105XPH Ferredoxin HUU83_RS14850 ENOG4105FQR PH-inducible protein involved in stress response HUU83_RS14860 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase HUU83_RS14865 ENOG4105CXY transporter HUU83_RS14870 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A HUU83_RS14880 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) HUU83_RS14885 ENOG4105DNE Transposase HUU83_RS14900 ENOG4108UII YfaZ family HUU83_RS14950 ENOG4106GZG polymyxin resistance protein B HUU83_RS14955 ENOG4105CEY Amp-dependent synthetase and ligase HUU83_RS14965 ENOG4108IPT Naphthoate synthase HUU83_RS14980 ENOG4105E4F Isochorismate synthase HUU83_RS14985 ENOG4105TNS Conserved Protein HUU83_RS14990 ENOG4107YB6 acetyltransferase, (GNAT) family HUU83_RS15010 ENOG4105GDX Domain of unknown function (DUF1877) HUU83_RS15020 ENOG4105C8S subunit m HUU83_RS15025 ENOG4105D65 subunit l HUU83_RS15035 ENOG4107UFS subunit j HUU83_RS15050 ENOG4108IEH NADH dehydrogenase subunit g HUU83_RS15055 ENOG4107QIZ NADH dehydrogenase HUU83_RS15060 ENOG4105GKE subunit e HUU83_RS15080 ENOG4107NQ8 LysR family Transcriptional regulator HUU83_RS15085 ENOG4105CHM Aminotransferase HUU83_RS15095 ENOG4107QWE )-transporter HUU83_RS15100 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 HUU83_RS15105 ENOG4105XWI UPF0304 protein HUU83_RS15115 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) HUU83_RS15120 ENOG4105C6K Malic enzyme HUU83_RS15125 ENOG4105CSX c4-dicarboxylate anaerobic carrier HUU83_RS15130 ENOG4105PTV Nudix Hydrolase HUU83_RS15135 ENOG4108RE9 Phosphodiesterase HUU83_RS15140 ENOG4108SHQ Glutathione S-transferase HUU83_RS15145 ENOG4105CYM Glutathione S-transferase HUU83_RS15150 ENOG4105KKP D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase HUU83_RS15155 ENOG4105ECP epimerase HUU83_RS15160 ENOG4105DNE Transposase HUU83_RS15165 ENOG4108JEH abc transporter atp-binding protein HUU83_RS15170 ENOG4106YG3 ABC transporter HUU83_RS15175 ENOG4105DSP amino acid AbC transporter HUU83_RS15180 ENOG4105E89 ABC transporter HUU83_RS15185 ENOG4105E89 ABC transporter HUU83_RS15190 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase HUU83_RS15195 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase HUU83_RS15200 ENOG4105E96 Colicin v production protein HUU83_RS15205 ENOG4108S3P Sporulation domain protein HUU83_RS15210 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase HUU83_RS15220 ENOG4105DQR SNARE associated Golgi HUU83_RS15230 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) HUU83_RS15240 ENOG4106WZ1 flagella biosynthesis regulator HUU83_RS15245 ENOG4105F9N Major Facilitator Superfamily HUU83_RS15250 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) HUU83_RS15255 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) HUU83_RS15260 ENOG4105MH2 YfcL protein HUU83_RS15265 ENOG4108BPE -transporting atpase HUU83_RS15270 ENOG4105EJ9 Membrane HUU83_RS15275 ENOG4105HPZ Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity) HUU83_RS15280 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase HUU83_RS15300 ENOG4105US4 fimbrial-like protein yfcP HUU83_RS15305 ENOG4105UGQ Fimbrial HUU83_RS15310 ENOG4105NEV Fimbrial HUU83_RS15315 ENOG4108FZ9 Chaperone HUU83_RS15320 ENOG4106PG1 outer membrane usher protein HUU83_RS15330 ENOG4108BY2 phosphohistidine phosphatase HUU83_RS15345 ENOG4105KZW UPF0381 protein HUU83_RS15350 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation HUU83_RS15360 ENOG410903C (LipO)protein HUU83_RS15365 ENOG4105S64 Formate nitrite transporter HUU83_RS15375 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) HUU83_RS15380 ENOG4105D7K pfkb domain protein HUU83_RS15385 ENOG4108HKT sucrose-6-phosphate hydrolase HUU83_RS15390 ENOG4106NDP Transcriptional regulator HUU83_RS15405 ENOG4105C0R drug resistance transporter emrb qaca subfamily HUU83_RS15410 ENOG4105CW7 secretion protein, HlyD family HUU83_RS15415 ENOG4108WQH regulatoR HUU83_RS15420 ENOG4105BZU Histidine kinase HUU83_RS15425 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F HUU83_RS15430 ENOG4108N2Y auxin Efflux HUU83_RS15435 ENOG4105CFN oxalyl-CoA decarboxylase HUU83_RS15445 ENOG4108V08 YfdX protein HUU83_RS15455 ENOG4105W9M Membrane HUU83_RS15460 ENOG4105D1S lipid A biosynthesis HUU83_RS15470 ENOG4105CHM Aminotransferase HUU83_RS15475 ENOG4108HRK Histidine kinase HUU83_RS15480 ENOG4105DY9 regulatoR HUU83_RS15485 ENOG4108CIP transcriptional regulator HUU83_RS15490 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) HUU83_RS15495 ENOG4105CN9 Peptidase m42 family protein HUU83_RS15500 ENOG4105DC7 peptidase M24 HUU83_RS15505 ENOG410863U PTS System HUU83_RS15510 ENOG4105R6B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) HUU83_RS15525 ENOG4109076 Conserved Protein HUU83_RS15535 ENOG4105D9N nucleoside HUU83_RS15540 ENOG4108KMM Diguanylate cyclase HUU83_RS15555 ENOG4105HZG regulatoR HUU83_RS15560 ENOG4105GXM Putative transcription regulator (DUF1323) HUU83_RS15590 ENOG4105CN8 Transcriptional regulator HUU83_RS15600 ENOG4105EAA nucleoside HUU83_RS15605 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) HUU83_RS15655 ENOG4108NFH Sugar hydrolase HUU83_RS15660 ENOG4108M0I Transcriptional regulator HUU83_RS15665 ENOG4105DHU Bile acid HUU83_RS15670 ENOG4105VRT cytoplasmic protein HUU83_RS15690 ENOG4105C6T cysteine synthase HUU83_RS15700 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) HUU83_RS15705 ENOG4105C5Y PTS System HUU83_RS15715 ENOG4105M0Y HUU83_RS15720 ENOG4105C6T cysteine synthase HUU83_RS15725 ENOG4108IJ6 ABC transporter HUU83_RS15730 ENOG4105ECW sulfate abc transporter HUU83_RS15735 ENOG4108I5D sulfate abc transporter HUU83_RS15740 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein HUU83_RS15745 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr HUU83_RS15760 ENOG4105C5Y PTS System HUU83_RS15765 ENOG4107S1E Beta-lactamase HUU83_RS15770 ENOG4105EZR dyp-type peroxidase family protein HUU83_RS15775 ENOG4105E7K (LipO)protein HUU83_RS15780 ENOG4105QZU Inner membrane protein YfeZ HUU83_RS15790 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase HUU83_RS15800 ENOG4108K3Z AraC family transcriptional regulator HUU83_RS15805 ENOG4108X49 Ethanolamine utilization protein EutK HUU83_RS15810 ENOG4106D67 ethanolamine utilization protein HUU83_RS15820 ENOG4105CPD ethanolamine ammonia-lyase HUU83_RS15825 ENOG4105DYY Reactivating factor for ethanolamine ammonia lyase HUU83_RS15830 ENOG4105ENY Ethanolamine utilization protein eutH HUU83_RS15835 ENOG4105C0A alcohol dehydrogenase HUU83_RS15840 ENOG4107RWI ethanolamine utilization protein eutJ HUU83_RS15845 ENOG4108EKI Dehydrogenase HUU83_RS15850 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml HUU83_RS15855 ENOG4105KNY Microcompartments protein HUU83_RS15860 ENOG4107WUY phosphate acetyltransferase HUU83_RS15865 ENOG4108PFF ethanolamine utilization cobalamin adenosyltransferase HUU83_RS15870 ENOG4105NDK ethanolamine utilization protein HUU83_RS15875 ENOG4106S4J ethanolamine utilization protein EutP HUU83_RS15880 ENOG4108VJN May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place HUU83_RS15885 ENOG4105C6K Malic enzyme HUU83_RS15890 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) HUU83_RS15895 ENOG4105CV1 Transketolase (EC 2.2.1.1) HUU83_RS15900 ENOG4108PVD exported protein HUU83_RS15910 ENOG4105BZ8 glutamate synthase HUU83_RS15915 ENOG4105BZU Histidine kinase HUU83_RS15920 ENOG4105BZS acriflavin resistance protein HUU83_RS15930 ENOG4105KUZ arsenate reductase HUU83_RS15945 ENOG4106KED esterase YpfH HUU83_RS15950 ENOG4105E0I Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity) HUU83_RS15955 ENOG4105CGZ zinc metallopeptidase HUU83_RS15960 ENOG4105M0J Toxic component of a toxin-antitoxin (TA) module. A HUU83_RS15975 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) HUU83_RS15985 ENOG4105RH4 Glycine cleavage system transcriptional repressor HUU83_RS15990 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen HUU83_RS15995 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) HUU83_RS16010 ENOG4105D65 subunit l HUU83_RS16020 ENOG4107WQX hydrogenase 4 membrane subunit HUU83_RS16025 ENOG4108JPZ Monovalent cation H antiporter subunit D HUU83_RS16030 ENOG4108JPZ Monovalent cation H antiporter subunit D HUU83_RS16035 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) HUU83_RS16050 ENOG4105I6X formate hydrogenlyase maturation HUU83_RS16055 ENOG4108JUA Transcriptional regulator HUU83_RS16060 ENOG4105TMB Formate nitrite transporter HUU83_RS16065 ENOG4105TMB Formate nitrite transporter HUU83_RS16070 ENOG4105C02 permease HUU83_RS16075 ENOG4105ERG peptidase m48, ste24p HUU83_RS16080 ENOG4105K89 arsenate reductase HUU83_RS16085 ENOG4108KZ1 Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity) HUU83_RS16090 ENOG4105C2W permease HUU83_RS16105 ENOG4108V3E phosphoribosylglycinamide formyltransferase HUU83_RS16110 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) HUU83_RS16115 ENOG4105C9X ppx gppa phosphatase HUU83_RS16120 ENOG4105BZU Histidine kinase HUU83_RS16130 ENOG41062G3 Protein of unknown function (DUF2633) HUU83_RS16135 ENOG4108ZMA Outer membrane lipoprotein HUU83_RS16140 ENOG41066DY Membrane HUU83_RS16150 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) HUU83_RS16160 ENOG4105VPD cellular component movement HUU83_RS16175 ENOG4105N21 Membrane HUU83_RS16205 ENOG4108JQB penicillin-binding protein 1C HUU83_RS16210 ENOG4105DN3 alpha-2-macroglobulin domain protein HUU83_RS16215 ENOG4105KHC sulfurtransferase HUU83_RS16220 ENOG4105YYA enhanced serine sensitivity protein SseB HUU83_RS16230 ENOG4105WVQ Fe-S assembly protein IscX HUU83_RS16235 ENOG4108ZIT Ferredoxin, 2FE-2S HUU83_RS16255 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins HUU83_RS16275 ENOG4105ECY inositol monophosphatase HUU83_RS16280 ENOG4107XM9 (LipO)protein HUU83_RS16285 ENOG4108MN2 Stationary phase inducible protein CsiE HUU83_RS16290 ENOG4105D8G Major Facilitator superfamily HUU83_RS16295 ENOG4108W5M transcriptional regulator HUU83_RS16300 ENOG4105FUY alpha subunit HUU83_RS16325 ENOG4108SB3 DoxX Family HUU83_RS16330 ENOG4108ZKT aldose 1-epimerase HUU83_RS16335 ENOG4105CPQ Dehydrogenase HUU83_RS16340 ENOG4105CNN ABC, transporter HUU83_RS16345 ENOG4108F37 ATP-binding component of a transport system HUU83_RS16350 ENOG4105FCA ABC transporter periplasmic-binding protein YphF HUU83_RS16355 ENOG4107HQ7 repeat protein HUU83_RS16360 ENOG4108NZE NAGC-like transcriptional regulator HUU83_RS16370 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) HUU83_RS16380 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HUU83_RS16385 ENOG4108SKK alpha helix protein HUU83_RS16390 ENOG4107WP9 Histidine kinase HUU83_RS16405 ENOG4108Z6B deaminase HUU83_RS16410 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB HUU83_RS16415 ENOG4106G6Q Transcriptional regulator HUU83_RS16420 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding HUU83_RS16435 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) HUU83_RS16455 ENOG4105C3F Signal peptidase i HUU83_RS16465 ENOG4105WMJ Positive regulator of sigma E, RseC MucC HUU83_RS16470 ENOG4105VQK sigma E regulatory protein, MucB RseB HUU83_RS16475 ENOG41069PW sigma-e factor negative regulatory protein HUU83_RS16480 ENOG4105EMN RNA polymerase sigma factor HUU83_RS16490 ENOG4108IYU L-aspartate oxidase HUU83_RS16500 ENOG4105C1J atp-dependent rna helicase HUU83_RS16510 ENOG41090KR LysR family transcriptional Regulator HUU83_RS16530 ENOG4105EIB trna rrna methyltransferase HUU83_RS16535 ENOG4105K63 Thioredoxin HUU83_RS16540 ENOG4106IUH DTW domain containing protein HUU83_RS16545 ENOG4105CD5 CoA-binding domain protein HUU83_RS16550 ENOG4105JIM Phosphatidylserine synthase HUU83_RS16555 ENOG4105T42 (LipO)protein HUU83_RS16560 ENOG4105CSH Transporter HUU83_RS16585 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit HUU83_RS16590 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase HUU83_RS16595 ENOG4105C34 Pseudouridine synthase HUU83_RS16600 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane HUU83_RS16605 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA HUU83_RS16615 ENOG4105CQC Prephenate dehydratase HUU83_RS16620 ENOG4105EHE chorismate mutase- prephenate dehydrogenase HUU83_RS16625 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) HUU83_RS16630 ENOG4105QP9 Protein of unknown function (DUF2799) HUU83_RS16635 ENOG4108WS1 HUU83_RS16640 ENOG4108KHX Diguanylate cyclase HUU83_RS16645 ENOG41090EK ompa motb domain protein HUU83_RS16670 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY HUU83_RS16675 ENOG4106KVJ cytochrome C assembly protein HUU83_RS16680 ENOG4108JU6 CBS domain protein HUU83_RS16695 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) HUU83_RS16700 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) HUU83_RS16710 ENOG4108Z1B Cyclase dehydrase HUU83_RS16760 ENOG4105D5U fad dependent oxidoreductase HUU83_RS16765 ENOG4105C26 Dehydrogenase HUU83_RS16770 ENOG4108JPW Aminotransferase HUU83_RS16775 ENOG4105C85 amino acid HUU83_RS16780 ENOG4108PVQ transcriptional regulator HUU83_RS16785 ENOG4109066 lysm domain bon superfamily protein HUU83_RS16790 ENOG4105VPI YqaE family transport protein HUU83_RS16795 ENOG41080HT Transcriptional regulator, arsr family HUU83_RS16800 ENOG4108V62 Rhodanese domain protein HUU83_RS16805 ENOG4108X73 DNA- binding protein HUU83_RS16810 ENOG4108RNS Exports L-alanine (By similarity) HUU83_RS16815 ENOG4108WMJ Protein of unknown function (DUF2002) HUU83_RS16820 ENOG4108ZQZ Bacterial protein of unknown function (DUF883) HUU83_RS16825 ENOG4105WAZ (Glutaredoxin-like protein) NrdH HUU83_RS16835 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HUU83_RS16840 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HUU83_RS16850 ENOG4108HQS Glycine betaine HUU83_RS16855 ENOG4105GIJ Glycine betaine HUU83_RS16865 ENOG4108UMN azlc family HUU83_RS16870 ENOG4105ZED uncharacterized protein ygaH HUU83_RS16875 ENOG4105NTK Transcriptional repressor Mpra HUU83_RS16880 ENOG4105CW7 secretion protein, HlyD family HUU83_RS16885 ENOG4105C0R drug resistance transporter emrb qaca subfamily HUU83_RS16900 ENOG4105W39 Membrane HUU83_RS16905 ENOG4107VXZ Hydrolase HUU83_RS16935 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) HUU83_RS16955 ENOG4107TH8 cina domain protein HUU83_RS16960 ENOG4105CVE Lytic murein transglycosylase HUU83_RS16965 ENOG410787A Pts system, glucitol sorbitol-specific HUU83_RS16970 ENOG4105DZY Pts system, glucitol sorbitol-specific HUU83_RS16975 ENOG4105VI0 Pts system, glucitol sorbitol-specific HUU83_RS16980 ENOG4107QMF Sorbitol-6-phosphate dehydrogenase HUU83_RS16985 ENOG4105J92 DNA-binding transcriptional activator GutM HUU83_RS16990 ENOG410804X Transcriptional regulator HUU83_RS16995 ENOG4105C2X Arabinose 5-phosphate isomerase HUU83_RS17015 ENOG4105C8H hydrogenase maturation protein Hypf HUU83_RS17020 ENOG4108RC0 Electron transport protein HUU83_RS17025 ENOG4105DDV Transcriptional regulator (LacI family HUU83_RS17030 ENOG4105C5Y PTS System HUU83_RS17035 ENOG4105CS2 ec 3.2.1.21 HUU83_RS17040 ENOG4108MG9 hydrogenase 3 maturation protease HUU83_RS17045 ENOG4105I6X formate hydrogenlyase maturation HUU83_RS17050 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit HUU83_RS17055 ENOG4108RG7 formate hydrogenlyase complex iron-sulfur subunit HUU83_RS17060 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) HUU83_RS17065 ENOG4107TDF Formate hydrogenlyase subunit 4 HUU83_RS17070 ENOG4107R30 NADH dehydrogenase HUU83_RS17075 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) HUU83_RS17080 ENOG4108VRC Formate hydrogenlyase regulatory protein hycA HUU83_RS17085 ENOG410816D Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) HUU83_RS17090 ENOG4107RSS Hydrogenase accessory protein HypB HUU83_RS17095 ENOG41083WG hydrogenase assembly chaperone HUU83_RS17100 ENOG4105CQS hydrogenase expression formation protein HypD HUU83_RS17105 ENOG4105C45 hydrogenase expression formation protein (HypE) HUU83_RS17110 ENOG4108JUA Transcriptional regulator HUU83_RS17115 ENOG4105VXR cytoplasmic protein HUU83_RS17130 ENOG4105MEW serine threonine protein phosphatase HUU83_RS17135 ENOG4105MVE transcriptional regulator HUU83_RS17140 ENOG4105ZXK Dehydrogenase HUU83_RS17145 ENOG4105G63 Type III effector Hrp-dependent HUU83_RS17150 ENOG4105FB2 class II Aldolase HUU83_RS17155 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) HUU83_RS17160 ENOG4105C6Z Gluconate HUU83_RS17165 ENOG4105KZM cytoplasmic protein HUU83_RS17170 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) HUU83_RS17175 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase HUU83_RS17185 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HUU83_RS17190 ENOG4108K5P (LipO)protein HUU83_RS17225 ENOG4105N0Z inner membrane protein ygbE HUU83_RS17240 ENOG4105C11 sulfate adenylyltransferase), subunit 2 HUU83_RS17245 ENOG4108MXK alkaline phosphatase isozyme conversion HUU83_RS17255 ENOG4105TZK CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) HUU83_RS17265 ENOG4108VWQ crispr-associated protein HUU83_RS17270 ENOG41060M0 Crispr-associated protein, cse4 family HUU83_RS17280 ENOG4105CYR Crispr-associated protein, cse1 family HUU83_RS17285 ENOG4105DTT CRISPR-associated helicase, cas3 HUU83_RS17290 ENOG4107635 Hok Gef family protein HUU83_RS17310 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase HUU83_RS17315 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase HUU83_RS17320 ENOG4105WQV ferredoxin-like protein HUU83_RS17325 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator HUU83_RS17330 ENOG4105YBM electron transfer flavoprotein subunit ygcQ HUU83_RS17335 ENOG4106IKH Electron transfer flavoprotein HUU83_RS17340 ENOG4105C54 Major Facilitator superfamily HUU83_RS17345 ENOG4107R3A FAD linked oxidase domain protein HUU83_RS17350 ENOG4105CHR reductase HUU83_RS17360 ENOG4108CWB sugar kinase ygcE HUU83_RS17365 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) HUU83_RS17390 ENOG4105DXN mazG family HUU83_RS17395 ENOG4105MZG transcriptional modulator of maze toxin, mazf HUU83_RS17400 ENOG4106A2Z transcriptional regulator antitoxin, MazE HUU83_RS17405 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) HUU83_RS17415 ENOG4105BZU Histidine kinase HUU83_RS17420 ENOG4105EQX glucarate dehydratase HUU83_RS17425 ENOG4105EQX glucarate dehydratase HUU83_RS17430 ENOG4105DJB Major Facilitator Superfamily HUU83_RS17435 ENOG4105QDK Flavodoxin HUU83_RS17440 ENOG4105DR9 pseudouridine synthase HUU83_RS17445 ENOG4105WP7 tRNA pseudouridine synthase C HUU83_RS17460 ENOG4105EWT decarboxylase family HUU83_RS17465 ENOG4105C44 Serine transporter HUU83_RS17470 ENOG4105EJQ L-serine dehydratase HUU83_RS17480 ENOG4105C0A alcohol dehydrogenase HUU83_RS17485 ENOG4107W7X Aldolase HUU83_RS17490 ENOG4105EDR glucose galactose transporter HUU83_RS17500 ENOG4105CMG Carbohydrate kinase HUU83_RS17510 ENOG4107EDW L-fucose operon activator HUU83_RS17520 ENOG4105M08 Membrane HUU83_RS17525 ENOG4105ETT transcriptional Regulator, LysR family HUU83_RS17530 ENOG4105M5B (LipO)protein HUU83_RS17535 ENOG4105C9B Cysteine desulfurase HUU83_RS17540 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) HUU83_RS17545 ENOG4105CUZ uba thif-type nad fad binding protein HUU83_RS17550 ENOG4105CA3 membrane-bound lytic murein transglycosylase HUU83_RS17570 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase HUU83_RS17575 ENOG4108EKC n-acetylglutamate synthase HUU83_RS17580 ENOG4107QYX exodeoxyribonuclease v alpha HUU83_RS17585 ENOG4107QKA exodeoxyribonuclease V beta HUU83_RS17590 ENOG4107QXK peptidase HUU83_RS17595 ENOG4105DSY exodeoxyribonuclease V, gamma HUU83_RS17600 ENOG4105RVB Prepilin peptidase dependent protein c HUU83_RS17605 ENOG4105SEN Protein of unknown function (DUF2509) HUU83_RS17610 ENOG4105JCS prepilin peptidase dependent protein HUU83_RS17615 ENOG4105IPU prepilin peptidase dependent protein A HUU83_RS17630 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase HUU83_RS17645 ENOG4105EE5 Membrane protein terC HUU83_RS17650 ENOG4105SUV lipoprotein YgdR HUU83_RS17655 ENOG4105CPC Aldo Keto reductase HUU83_RS17660 ENOG4107S74 Lysophospholipid transporter LplT HUU83_RS17670 ENOG41060NJ transcriptional regulator HUU83_RS17680 ENOG4105RQF LysR family Transcriptional regulator HUU83_RS17690 ENOG4107QNK )-transporter HUU83_RS17695 ENOG4105CHR reductase HUU83_RS17705 ENOG4105CHU acetyl-coa acetyltransferase HUU83_RS17710 ENOG4108MHD transport protein HUU83_RS17715 ENOG4105ISV protein with bipartite regulator domain HUU83_RS17720 ENOG4108TC1 Transcriptional regulator HUU83_RS17725 ENOG4105FV3 HUU83_RS17750 ENOG4108YAB Invasion protein HUU83_RS17780 ENOG4108RBT type iii secretion HUU83_RS17795 ENOG4108RC9 Type III secretion system protein HUU83_RS17810 ENOG4108M6W surface presentation of antigens protein SpaS HUU83_RS17820 ENOG4108TN6 type iii secretion HUU83_RS17825 ENOG4105U07 type iii secretion HUU83_RS17830 ENOG41075IY surface presentation of antigens protein SpaP HUU83_RS17840 ENOG4108T88 HUU83_RS17850 ENOG4108K5P (LipO)protein HUU83_RS17855 ENOG4105C7W Xanthine dehydrogenase HUU83_RS17860 ENOG4108HR6 Dehydrogenase HUU83_RS17865 ENOG4108UTP (2Fe-2S)-binding domain protein HUU83_RS17870 ENOG4108JUB Transcriptional regulator HUU83_RS17875 ENOG4105IW6 Carbamoyltransferase HUU83_RS17880 ENOG4107RCH Diaminopropionate ammonia-lyase HUU83_RS17885 ENOG4107S4Y M20 DapE family protein YgeY HUU83_RS17895 ENOG4105C5B carbamate kinase HUU83_RS17900 ENOG4107P0T Selenium-dependent molybdenum hydroxylase system protein, YqeB family HUU83_RS17905 ENOG4105MJ6 selenium-dependent hydroxylase accessory protein YqeC HUU83_RS17910 ENOG4105MFX 4-diphosphocytidyl-2c-methyl-d-erythritol synthase HUU83_RS17915 ENOG4105BZ8 glutamate synthase HUU83_RS17920 ENOG4107UUR Chlorohydrolase aminohydrolase HUU83_RS17925 ENOG410873Y FAD binding domain in molybdopterin dehydrogenase HUU83_RS17930 ENOG4105C7W Xanthine dehydrogenase HUU83_RS17935 ENOG4105C2W permease HUU83_RS17940 ENOG4107QUY Guanine deaminase HUU83_RS17945 ENOG4105C7N Xanthine uracil vitamin C permease HUU83_RS17950 ENOG4108R8B oxidoreductase Fe-S subunit HUU83_RS17955 ENOG4105BZ8 glutamate synthase HUU83_RS17960 ENOG4105C2W permease HUU83_RS17975 ENOG4108ZEY Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity) HUU83_RS17990 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) HUU83_RS17995 ENOG4105T95 Thiol disulfide interChange protein HUU83_RS18000 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) HUU83_RS18005 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) HUU83_RS18010 ENOG4108YDB Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB HUU83_RS18015 ENOG4105Y75 tpr repeat protein HUU83_RS18025 ENOG4108UT2 hemolysin iii HUU83_RS18035 ENOG4105CS2 ec 3.2.1.21 HUU83_RS18040 ENOG4105CYX Short-chain dehydrogenase reductase Sdr HUU83_RS18065 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family HUU83_RS18070 ENOG4105D0A hydroxylase HUU83_RS18075 ENOG4107RAQ aminopeptidase HUU83_RS18095 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase HUU83_RS18110 ENOG4108JQ1 Dehydrogenase HUU83_RS18130 ENOG4105D5P Methylmalonyl-coA mutase HUU83_RS18135 ENOG4105DJT lAO AO transport system ATPase HUU83_RS18140 ENOG4108M7F enoyl-CoA hydratase isomerase HUU83_RS18145 ENOG4105CYC Transferase HUU83_RS18150 ENOG4105DEQ transcriptional regulator HUU83_RS18155 ENOG4105MPN Membrane HUU83_RS18160 ENOG4108ZUB Lysine exporter protein (Lyse ygga) HUU83_RS18165 ENOG4105D64 Mechanosensitive ion channel HUU83_RS18170 ENOG4105D2N Aldolase HUU83_RS18200 ENOG4108JJB ABC transporter HUU83_RS18205 ENOG4108JJB ABC transporter HUU83_RS18210 ENOG4107Z1W Fructose transport system kinase HUU83_RS18215 ENOG4108R4K DNA-binding, transcriptional regulator HUU83_RS18220 ENOG4108Q8A Fructose-1,6-bisphosphatase HUU83_RS18225 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein HUU83_RS18230 ENOG4105CTS PTS system mannitol-specific HUU83_RS18235 ENOG4108X7Y Mannitol-specific cryptic phosphotransferase enzyme iia HUU83_RS18240 ENOG4105CV1 Transketolase (EC 2.2.1.1) HUU83_RS18245 ENOG4108K0D peptidase, M48 HUU83_RS18255 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) HUU83_RS18275 ENOG4107QNK )-transporter HUU83_RS18285 ENOG4105RWS endonuclease I HUU83_RS18290 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) HUU83_RS18295 ENOG4105D7Z glutathione synthase HUU83_RS18315 ENOG4105DFA alanine racemase domain protein HUU83_RS18320 ENOG4108VIA integral membrane protein HUU83_RS18330 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) HUU83_RS18335 ENOG4105CSA Coproporphyrinogen iii oxidase HUU83_RS18340 ENOG4106MH3 alpha helix chain HUU83_RS18345 ENOG4105HDK L-asparaginase HUU83_RS18350 ENOG4105K33 Periplasmic Protein HUU83_RS18355 ENOG41090ED Protein with unknown function (DUF469) HUU83_RS18365 ENOG4105CEN a g-specific adenine glycosylase HUU83_RS18380 ENOG4105EAA nucleoside HUU83_RS18385 ENOG4105CXN decarboxylase HUU83_RS18390 ENOG4108UQV Membrane HUU83_RS18400 ENOG4105U1E general secretion pathway protein M HUU83_RS18420 ENOG4105X5Z General secretion pathway protein I HUU83_RS18430 ENOG4108VAU general secretion pathway protein G HUU83_RS18435 ENOG4105D7Q type ii secretion system HUU83_RS18440 ENOG4107QHF type ii secretion system protein e HUU83_RS18465 ENOG4105F88 accessory colonization factor AcfD HUU83_RS18470 ENOG4105DAA L-lactate HUU83_RS18475 ENOG4107QP3 malate synthase g HUU83_RS18480 ENOG4108ZJF Glcg protein HUU83_RS18485 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) HUU83_RS18490 ENOG4105EU8 FAD linked oxidase domain protein HUU83_RS18495 ENOG4105CQB FAD linked oxidase domain protein HUU83_RS18500 ENOG4108KWP DNA-binding transcriptional regulator GlcC HUU83_RS18510 ENOG4107RCI amp-dependent synthetase and ligase HUU83_RS18520 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) HUU83_RS18525 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) HUU83_RS18535 ENOG4108M8S permease YjgP YjgQ family protein HUU83_RS18540 ENOG4108UUE Transcriptional regulator HUU83_RS18550 ENOG4108S55 polysaccharide biosynthesis protein HUU83_RS18555 ENOG4106FPV ATP-binding protein YghR HUU83_RS18560 ENOG4108NDC ATP-binding protein yghS HUU83_RS18565 ENOG4108GH0 ATP-binding protein yghT HUU83_RS18570 ENOG4105CJ3 phosphate transporter HUU83_RS18575 ENOG4106032 Glutathionylspermidine synthase HUU83_RS18580 ENOG4105CYM Glutathione S-transferase HUU83_RS18590 ENOG4105DEN Luciferase family HUU83_RS18610 ENOG4108YYD acetyltransferase HUU83_RS18625 ENOG4107R7Y intracellular protease Pfpi family HUU83_RS18630 ENOG4105K4T epimerase HUU83_RS18635 ENOG4107S21 permease HUU83_RS18640 ENOG4105W4M Transport-associated protein HUU83_RS18660 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) HUU83_RS18665 ENOG4105I74 Fimbrial protein HUU83_RS18670 ENOG4105CW0 outer membrane usher protein HUU83_RS18675 ENOG4108VCD Chaperone HUU83_RS18680 ENOG4105Q10 Fimbrial-like protein HUU83_RS18685 ENOG4106HBN Galactosamine-6-phosphate isomerase HUU83_RS18690 ENOG4105F3R pts system mannose fructose sorbose family iid HUU83_RS18695 ENOG4105ETZ PTS System HUU83_RS18700 ENOG4108UZY PTS System HUU83_RS18710 ENOG4105E70 isomerase HUU83_RS18715 ENOG4105CE4 GlcNAc 6-P deacetylase HUU83_RS18720 ENOG4108YTN IIa component HUU83_RS18725 ENOG4105F3R pts system mannose fructose sorbose family iid HUU83_RS18735 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB HUU83_RS18745 ENOG4105E98 transcriptional regulator DeoR family HUU83_RS18750 ENOG4108R8Z these effects are overcome by concomitant expression of antitoxin SohA (PrlF). Massive overexpression is toxic. Unlike most other characterized TA systems degrades rRNA, and co-folding of the proteins is necessary in vitro for inhibition of the RNase activity. It is not known if it has any sequence-specificity. Acts as a transcription factor. The YhaV PrlF complex binds the prlF-yhaV operon, probably negatively regulating its expression HUU83_RS18755 ENOG4105ZEG Suppressor protein HUU83_RS18760 ENOG4105CTX dehydratase HUU83_RS18765 ENOG4105DJB Major Facilitator Superfamily HUU83_RS18775 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase HUU83_RS18780 ENOG4105BZW Glycerate kinase HUU83_RS18805 ENOG410811B TRANSCRIPTIONal HUU83_RS18810 ENOG4105C7B Threonine dehydratase HUU83_RS18820 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) HUU83_RS18825 ENOG4105C6N Formate acetyltransferase HUU83_RS18830 ENOG4105KME endoribonuclease L-psp HUU83_RS18835 ENOG4105EJQ L-serine dehydratase HUU83_RS18840 ENOG4105C44 Serine transporter HUU83_RS18850 ENOG4106D80 Uncharacterized protein YhaL HUU83_RS18855 ENOG4108CNN domain protein HUU83_RS18860 ENOG4105CWB LysR family transcriptional Regulator HUU83_RS18865 ENOG4105KAF membrAne HUU83_RS18870 ENOG4105KAF membrAne HUU83_RS18875 ENOG4105CHF Glutathione S-transferase HUU83_RS18880 ENOG4108VBZ doxx family HUU83_RS18885 ENOG4105YJD HUU83_RS18890 ENOG41090KG Inner membrane protein YqjE HUU83_RS18895 ENOG4105NE1 Conserved Protein HUU83_RS18900 ENOG4105WAY exported protein HUU83_RS18905 ENOG4105IYR Modulates the activity of the EnvZ OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR (By similarity) HUU83_RS18910 ENOG4106W5V Membrane HUU83_RS18915 ENOG4107YCY Transcriptional regulator HUU83_RS18940 ENOG4105DPW Major facilitator superfamily MFS_1 HUU83_RS18950 ENOG4105CTX dehydratase HUU83_RS18955 ENOG4105P66 Membrane HUU83_RS18960 ENOG4107QV7 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity) HUU83_RS18965 ENOG4105DU1 integral membrane protein, terc HUU83_RS18970 ENOG4105EE0 oxidoreductase HUU83_RS18975 ENOG4108UB4 uncharacterized protein ygjQ HUU83_RS18980 ENOG4108VKG metal-dependent hydrolase HUU83_RS18995 ENOG4108Z3N Transcriptional regulator HUU83_RS19000 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase HUU83_RS19005 ENOG4107WCA isomerase HUU83_RS19010 ENOG4107W6W Conserved Protein HUU83_RS19015 ENOG4105E5D amino acid HUU83_RS19020 ENOG4105FK9 beta-D-galactosidase beta subunit HUU83_RS19025 ENOG4105CNT hydrolase family 2 HUU83_RS19030 ENOG4105CQ4 Transcriptional regulator HUU83_RS19035 ENOG4108Y51 tRNA-binding protein HUU83_RS19045 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor HUU83_RS19050 ENOG4105NTW Transcriptional regulator HUU83_RS19055 ENOG4105Q26 Siderophore-interacting protein HUU83_RS19085 ENOG410693A DNA-binding protein HUU83_RS19090 ENOG4105JXR Protein of unknown function (DUF3296) HUU83_RS19130 ENOG4105C5Y PTS System HUU83_RS19145 ENOG4105D7K pfkb domain protein HUU83_RS19165 ENOG4105EKQ RNA-directed DNA polymerase HUU83_RS19220 ENOG4105DZR Type I site-specific deoxyribonuclease HUU83_RS19240 ENOG4105F4K antigen 43 HUU83_RS19245 ENOG4106H6R UPF0380 protein HUU83_RS19250 ENOG4106549 Antirestriction protein HUU83_RS19255 ENOG4108YGG dna repair protein HUU83_RS19265 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles HUU83_RS19300 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HUU83_RS19305 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) HUU83_RS19320 ENOG4107QPK )-transporter HUU83_RS19325 ENOG4107GFK fumarate HUU83_RS19330 ENOG4106DSS Tartrate dehydratase subunit alpha HUU83_RS19335 ENOG4105EJC lysr family transcriptional regulator HUU83_RS19345 ENOG4107ZVW dihydroneopterin aldolase HUU83_RS19360 ENOG4106MWK domain protein HUU83_RS19365 ENOG4105I7R Adenylate cyclase HUU83_RS19390 ENOG4107S78 Band 7 protein HUU83_RS19395 ENOG4105PV3 Inner membrane protein yqiJ HUU83_RS19405 ENOG4108MY7 Fimbrial HUU83_RS19410 ENOG4108TTM chaperone HUU83_RS19420 ENOG4105H8W Fimbrial protein HUU83_RS19425 ENOG4105W0Z cytoplasmic protein HUU83_RS19445 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b HUU83_RS19450 ENOG4106032 Glutathionylspermidine synthase HUU83_RS19460 ENOG4105DFG type I secretion outer membrane protein HUU83_RS19465 ENOG41087AY ADP-Ribose pyrophosphatase HUU83_RS19470 ENOG4108SX3 cytoplasmic protein HUU83_RS19475 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) HUU83_RS19480 ENOG4105IPS esterase HUU83_RS19485 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HUU83_RS19490 ENOG4105VRH Antibiotic biosynthesis monooxygenase HUU83_RS19495 ENOG4105NF4 modulator of drug activity HUU83_RS19500 ENOG4107DEU Inner membrane protein YgiZ HUU83_RS19505 ENOG4105DHQ Histidine kinase HUU83_RS19510 ENOG4105XJC Two component transcriptional regulator (Winged helix family HUU83_RS19515 ENOG4105H4F exported protein HUU83_RS19520 ENOG4105F4I Transcriptional regulator HUU83_RS19525 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HUU83_RS19530 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase HUU83_RS19535 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) HUU83_RS19540 ENOG4105CCT upf0313 protein HUU83_RS19550 ENOG4105ZKC Conserved Protein HUU83_RS19555 ENOG4105CV8 reductase HUU83_RS19560 ENOG4108I6A alcohol dehydrogenase HUU83_RS19565 ENOG4105CF7 AraC family transcriptional regulator HUU83_RS19570 ENOG4108K81 inner membrane protein YghB HUU83_RS19575 ENOG4105C28 cystathionine HUU83_RS19580 ENOG4105CWK Biopolymer transport protein, ExbB HUU83_RS19585 ENOG4108ZZF transport protein (ExbD) HUU83_RS19590 ENOG4105CYX Short-chain dehydrogenase reductase Sdr HUU83_RS19600 ENOG4105CPC Aldo Keto reductase HUU83_RS19610 ENOG410900S Protein of unknown function (DUF2623) HUU83_RS19615 ENOG4105E3S small subunit HUU83_RS19620 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HUU83_RS19625 ENOG4105CJ5 hydrogenase 2 b cytochrome subunit HUU83_RS19630 ENOG4105DPX Hydrogenase, large subunit HUU83_RS19635 ENOG4108USZ hydrogenase HUU83_RS19640 ENOG4108WGS hydrogenase 2-specific chaperone HUU83_RS19645 ENOG4105WMM Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) HUU83_RS19650 ENOG41082MF Hydrogenase assembly chaperone hypC hupF HUU83_RS19660 ENOG4105CIC tryptophan-specific transport protein HUU83_RS19665 ENOG4105C1J atp-dependent rna helicase HUU83_RS19705 ENOG4105CHV Transcription elongation factor NusA HUU83_RS19725 ENOG4105DIJ Phosphoethanolamine transferase HUU83_RS19735 ENOG4105NTZ Preprotein translocase subunit SecG HUU83_RS19745 ENOG4105EEI dihydropteroate synthase HUU83_RS19750 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) HUU83_RS19760 ENOG4105HBR Rna-binding protein HUU83_RS19765 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) HUU83_RS19770 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase HUU83_RS19780 ENOG4105QYV Membrane HUU83_RS19795 ENOG4105EAH synthase HUU83_RS19800 ENOG4105HVQ Regulatory factor of maltose metabolism HUU83_RS19810 ENOG4105VFK BolA family HUU83_RS19815 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane HUU83_RS19820 ENOG4105E3I toluene tolerance HUU83_RS19825 ENOG4107PE3 Mammalian cell entry related domain protein HUU83_RS19830 ENOG4105CY3 ABC transporter, permease HUU83_RS19835 ENOG4105DHJ ABC, transporter HUU83_RS19840 ENOG4105FEU K -dependent Na -Ca exchanger HUU83_RS19845 ENOG4105C2X Arabinose 5-phosphate isomerase HUU83_RS19855 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) HUU83_RS19860 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA HUU83_RS19865 ENOG4108IUZ ABC transporter HUU83_RS19870 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HUU83_RS19875 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA HUU83_RS19880 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN HUU83_RS19890 ENOG41080Z8 PHOSPHOCARRIER protein HUU83_RS19895 ENOG4108NIH transferase activity, transferring phosphorus-containing groups HUU83_RS19905 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain HUU83_RS19910 ENOG4105BZU Histidine kinase HUU83_RS19915 ENOG4105N5T Radical SAM Protein HUU83_RS19920 ENOG4105CBC glutamate synthase HUU83_RS19925 ENOG4105BZ8 glutamate synthase HUU83_RS19930 ENOG4105DFS Conserved Protein HUU83_RS19940 ENOG4108R66 Conserved Protein HUU83_RS19955 ENOG4105JHE Major Facilitator Superfamily HUU83_RS19975 ENOG4105CEE C4-dicarboxylate transporter HUU83_RS19980 ENOG4105KB2 stringent starvation protein b HUU83_RS19985 ENOG4107MKT Stringent starvation protein a HUU83_RS20000 ENOG4105D6Z AFG1 family ATPase HUU83_RS20005 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III HUU83_RS20010 ENOG4105C0H protease HUU83_RS20015 ENOG4105C0H protease HUU83_RS20030 ENOG4105RID UPF0379 protein yhcN HUU83_RS20035 ENOG4105UNR (Barnase) inhibitor HUU83_RS20050 ENOG4105ZQC membrane protein AaeX HUU83_RS20055 ENOG4105CR8 Transcriptional regulator HUU83_RS20060 ENOG4105D1U peptidase U62 modulator of DNA gyrase HUU83_RS20065 ENOG4105QD6 exported protein HUU83_RS20070 ENOG4105C03 ribonuclease HUU83_RS20080 ENOG4105VQ7 Rod shape-determining protein MreD HUU83_RS20085 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) HUU83_RS20095 ENOG41062P1 Diguanylate cyclase phosphodiesterase HUU83_RS20100 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family HUU83_RS20105 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein HUU83_RS20110 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase HUU83_RS20115 ENOG4105RG0 Membrane HUU83_RS20120 ENOG4108IA2 Sodium pantothenate symporter HUU83_RS20130 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) HUU83_RS20140 ENOG4105CEC DNA methylase N-4 N-6 HUU83_RS20145 ENOG41061ME transport protein HUU83_RS20150 ENOG4108XG4 DNA-binding transcriptional regulator HUU83_RS20155 ENOG4105C1P efflux transporter, rnd family, mfp subunit HUU83_RS20160 ENOG4105BZS acriflavin resistance protein HUU83_RS20165 ENOG4105XCM membrane LIPOPROTEIN HUU83_RS20175 ENOG4105EZ7 amino acid ABC transporter HUU83_RS20180 ENOG4105DRP amino acid AbC transporter HUU83_RS20185 ENOG4105CDA abc transporter atp-binding protein HUU83_RS20225 ENOG4108Z0R Transferase HUU83_RS20230 ENOG4105SG3 Protein of unknown function (DUF1488) HUU83_RS20245 ENOG4108WI1 Dna topoisomerase HUU83_RS20255 ENOG4105C79 DNA protecting protein DprA HUU83_RS20275 ENOG4105C1A potassium transporter peripheral membrane HUU83_RS20285 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system HUU83_RS20290 ENOG4105W1Y Transcriptional regulator HUU83_RS20295 ENOG4105VTS DnaJ-like, subfamily C HUU83_RS20325 ENOG41067V7 50S ribosomal protein L36 HUU83_RS20330 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) HUU83_RS20375 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) HUU83_RS20420 ENOG41080KG One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) HUU83_RS20445 ENOG4108UQY Iron-storage protein HUU83_RS20450 ENOG4105W53 bacterioferritin-associated ferredoxin HUU83_RS20490 ENOG4105WWK YheO domain protein HUU83_RS20495 ENOG4108V1T peptidylprolyl cis-trans isomerase HUU83_RS20505 ENOG4108YZY peptidylprolyl cis-trans isomerase HUU83_RS20510 ENOG4105VKU nucleicacid-binding protein HUU83_RS20525 ENOG4105C5H ABC transporter HUU83_RS20530 ENOG4105DNZ Alpha Beta Hydrolase HUU83_RS20540 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) HUU83_RS20545 ENOG4108UKZ OsmC family HUU83_RS20555 ENOG410613R integral membrane protein, YccS YhfK family HUU83_RS20560 ENOG4105C8Y Acetylornithine aminotransferase HUU83_RS20565 ENOG4105DDQ anthranilate synthase HUU83_RS20570 ENOG4105MZU cell filamentation protein HUU83_RS20580 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) HUU83_RS20590 ENOG4107QZF nitrite reductase NADPH large subunit HUU83_RS20595 ENOG4105WZK nitrite reductase NADPH small subunit HUU83_RS20600 ENOG4107V9H nitrite transporter HUU83_RS20610 ENOG4105VYH HUU83_RS20615 ENOG4106PKC pyridoxal phosphate binding HUU83_RS20620 ENOG4106M0N transport system permease protein HUU83_RS20625 ENOG4105MUZ Protein of unknown function DUF2620 HUU83_RS20630 ENOG41080QX K07048 phosphotriesterase-related protein HUU83_RS20635 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) HUU83_RS20640 ENOG4108626 Racemase HUU83_RS20645 ENOG4105RMW regulation of transcription, DNA-dependent HUU83_RS20650 ENOG4108M21 HUU83_RS20655 ENOG4105C31 Tryptophanyl-tRNA synthetase HUU83_RS20660 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) HUU83_RS20665 ENOG4105DJV ribulose-phosphate 3-epimerase HUU83_RS20670 ENOG4105DFE Dna adenine methylase HUU83_RS20675 ENOG4105EGB membrane protein DamX HUU83_RS20690 ENOG4105E4G Type IV pilus HUU83_RS20695 ENOG4105ITY Required for the use of extracellular DNA as a nutrient HUU83_RS20700 ENOG4105XPX DNA utilization protein HofO HUU83_RS20705 ENOG41065NF Fimbrial assembly family protein HUU83_RS20710 ENOG4108U1Q Pilus assembly protein HUU83_RS20715 ENOG4108JQC penicillin-binding protein 1A HUU83_RS20720 ENOG4107RK2 ADP-ribose diphosphatase NudE HUU83_RS20725 ENOG4105DQY intracellular growth attenuator HUU83_RS20730 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 HUU83_RS20735 ENOG4105VEJ Heat shock protein HUU83_RS20745 ENOG4108MAJ Membrane HUU83_RS20765 ENOG4105E0F Histidine kinase HUU83_RS20775 ENOG4108RRZ Transcription elongation factor GreB HUU83_RS20780 ENOG4105BZM domain protein HUU83_RS20785 ENOG4105XFK Ferrous iron transport protein A HUU83_RS20790 ENOG4105CE1 Ferrous iron transport protein b HUU83_RS20800 ENOG4105DNE Transposase HUU83_RS20810 ENOG4105MJ2 Competence protein HUU83_RS20820 ENOG4105C6Z Gluconate HUU83_RS20825 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) HUU83_RS20830 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) HUU83_RS20845 ENOG4105E0Y RtcB Protein HUU83_RS20850 ENOG4105CYB regulatoR HUU83_RS20855 ENOG4105E98 transcriptional regulator DeoR family HUU83_RS20870 ENOG4105C6V Glycerol-3-phosphate dehydrogenase HUU83_RS20895 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) HUU83_RS20920 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) HUU83_RS20925 ENOG41076UM multiple antibiotic resistance (MarC)-related protein HUU83_RS20930 ENOG4105C6Z Gluconate HUU83_RS20935 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family HUU83_RS20940 ENOG4105DIQ Transcriptional regulator HUU83_RS20950 ENOG4105D9R oxidoreductase HUU83_RS20955 ENOG4105WCN acetyltransferase HUU83_RS20960 ENOG4105GMB type VI secretion system effector, hcp1 family HUU83_RS20975 ENOG4106FA4 HUU83_RS20980 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) HUU83_RS20985 ENOG4105WC8 Conserved Protein HUU83_RS20990 ENOG4107T6V glycerophosphoryl diester phosphodiesterase HUU83_RS20995 ENOG4108IJ9 (ABC) transporter HUU83_RS21000 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component HUU83_RS21005 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component HUU83_RS21010 ENOG4105BZ7 extracellular solute-binding protein family 1 HUU83_RS21015 ENOG4108IV0 ABC, transporter HUU83_RS21020 ENOG4105C0Z ABC transporter HUU83_RS21025 ENOG4105CF8 branched-chain amino acid ABC transporter, permease HUU83_RS21030 ENOG4105C32 Amino acid ABC transporter (Permease) HUU83_RS21035 ENOG4105CP9 extracellular ligand-binding receptor HUU83_RS21040 ENOG4105U59 -acetyltransferase HUU83_RS21045 ENOG4105CP9 extracellular ligand-binding receptor HUU83_RS21050 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HUU83_RS21055 ENOG4105CRP Part of the ABC transporter FtsEX involved in HUU83_RS21060 ENOG4105CAK Cell division ATP-binding protein ftsE HUU83_RS21065 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) HUU83_RS21070 ENOG4106H78 methyltransferase HUU83_RS21075 ENOG4105MG3 Membrane HUU83_RS21085 ENOG4107FS9 Membrane HUU83_RS21100 ENOG4105EX9 Membrane HUU83_RS21105 ENOG4108W1V Lipoprotein HUU83_RS21110 ENOG4105F9N Major Facilitator Superfamily HUU83_RS21115 ENOG4105DSF transport protein HUU83_RS21120 ENOG4107YAK holo-(acyl carrier protein) synthase 2 HUU83_RS21125 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein HUU83_RS21130 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HUU83_RS21135 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HUU83_RS21140 ENOG4106665 Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) HUU83_RS21165 ENOG4105CMI transporter HUU83_RS21170 ENOG4105CJ1 ABC, transporter HUU83_RS21175 ENOG4105D0S secretion protein (HlyD HUU83_RS21190 ENOG4107UNS conserved inner membrane protein HUU83_RS21195 ENOG4105CBX hi0933 family HUU83_RS21200 ENOG4105CJ3 phosphate transporter HUU83_RS21215 ENOG4105DUX Transporter HUU83_RS21225 ENOG4105DGW oligopeptidase A HUU83_RS21230 ENOG4105D6S protein involved in catabolism of external DNA HUU83_RS21235 ENOG4105DC8 reductase HUU83_RS21245 ENOG4105KBH arsR family transcriptional regulator HUU83_RS21250 ENOG4107R5R arsenical pump membrane protein HUU83_RS21255 ENOG4105K89 arsenate reductase HUU83_RS21275 ENOG4105Y4Z Outer Membrane Lipoprotein HUU83_RS21285 ENOG4105KT7 mgtC SapB transporter HUU83_RS21290 ENOG4105XXV Acid-resistance protein HUU83_RS21295 ENOG41060V2 Acid-resistance protein HUU83_RS21300 ENOG4108YK4 Acid-resistance membrane protein HUU83_RS21305 ENOG4106WJ0 Regulates the expression of several genes involved in acid resistance. Required for the expression of gadA and gadBC, among others, regardless of media or growth conditions. Binds directly to the 20 bp GAD box found in the control regions of both loci HUU83_RS21315 ENOG4105C1P efflux transporter, rnd family, mfp subunit HUU83_RS21320 ENOG4105BZS acriflavin resistance protein HUU83_RS21330 ENOG4108NKV transcriptional regulator HUU83_RS21335 ENOG4105CVK Glutamate decarboxylase HUU83_RS21340 ENOG4105CA0 peroxidase HUU83_RS21350 ENOG4106S2D Transcriptional regulator HUU83_RS21355 ENOG4105CBN LysR family transcriptional regulator HUU83_RS21360 ENOG4107H3J ribonuclease HUU83_RS21365 ENOG4105CSH Transporter HUU83_RS21370 ENOG41066T0 asmA family HUU83_RS21375 ENOG4105CMB EAL domain-containing protein HUU83_RS21385 ENOG4105CS0 peptidase HUU83_RS21395 ENOG4105BZU Histidine kinase HUU83_RS21400 ENOG4105EJG cellulose synthase HUU83_RS21405 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) HUU83_RS21410 ENOG4107EEX Cellulose synthase regulator protein HUU83_RS21415 ENOG4107QZ7 Cellulose synthase catalytic subunit HUU83_RS21425 ENOG410661M cytoplasmic protein HUU83_RS21430 ENOG4105U74 cellulose biosynthesis protein BcsE HUU83_RS21435 ENOG4105WQA Cellulose biosynthesis protein BcsF HUU83_RS21440 ENOG4105D1V cellulose synthase operon protein YhjU HUU83_RS21460 ENOG4105C44 Serine transporter HUU83_RS21465 ENOG4108JQ7 (ABC) transporter HUU83_RS21470 ENOG4105C3U ABC transporter HUU83_RS21475 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HUU83_RS21480 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HUU83_RS21485 ENOG4105DEF Extracellular solute-binding protein, family 5 HUU83_RS21500 ENOG4105DIJ Phosphoethanolamine transferase HUU83_RS21505 ENOG4106UCC Fimbrial protein HUU83_RS21510 ENOG4105MHR Fimbrial protein HUU83_RS21515 ENOG4105CW0 outer membrane usher protein HUU83_RS21520 ENOG4108VCD Chaperone HUU83_RS21525 ENOG4106EAR Fimbrial protein HUU83_RS21530 ENOG4105FCD Major Facilitator HUU83_RS21535 ENOG4105EAX Putative lipase HUU83_RS21540 ENOG4108R3E Dna-3-methyladenine glycosylase i HUU83_RS21545 ENOG4105HNP -acetyltransferase HUU83_RS21550 ENOG4107QY8 reductase HUU83_RS21555 ENOG4108ZG0 Ompa motb domain protein HUU83_RS21565 ENOG4106JH6 (LipO)protein HUU83_RS21570 ENOG4105MVF Transcriptional regulator HUU83_RS21600 ENOG4105MEV Acyl-transferase HUU83_RS21605 ENOG4108Z12 YiaAB two helix domain-containing protein HUU83_RS21610 ENOG410688U Inner membrane protein yiaB HUU83_RS21615 ENOG4105CMG Carbohydrate kinase HUU83_RS21625 ENOG4105DFW ABC transporter HUU83_RS21630 ENOG4105C2J ABC transporter HUU83_RS21635 ENOG4108HWW ABC transporter HUU83_RS21640 ENOG4105T16 Transcriptional regulator (AraC family) HUU83_RS21645 ENOG4108UR8 BAX protein HUU83_RS21650 ENOG4107T9C Alpha amylase catalytic region HUU83_RS21655 ENOG4105JKW Valine--pyruvate aminotransferase HUU83_RS21660 ENOG4108XIB electron transport protein ysaA HUU83_RS21665 ENOG4105J4Q Transcriptional regulator HUU83_RS21675 ENOG4108R66 Conserved Protein HUU83_RS21680 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter HUU83_RS21685 ENOG4105CG6 trap dicarboxylate transporter dctm subunit HUU83_RS21690 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit HUU83_RS21695 ENOG4105CMG Carbohydrate kinase HUU83_RS21700 ENOG4105H6Q decarboxylase HUU83_RS21705 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase HUU83_RS21710 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase HUU83_RS21715 ENOG4105GNX MltA-interacting MipA family protein HUU83_RS21720 ENOG4108Q2M Transcriptional regulator HUU83_RS21725 ENOG4105EFX secretion protein, HlyD family HUU83_RS21730 ENOG4105KK7 inner membrane protein YiaW HUU83_RS21740 ENOG4105C26 Dehydrogenase HUU83_RS21745 ENOG4105C0A alcohol dehydrogenase HUU83_RS21750 ENOG4105EM7 Selenocysteine-specific translation elongation factor HUU83_RS21760 ENOG4108U78 Glutathione S-transferase HUU83_RS21765 ENOG4105CNA YD repeat protein HUU83_RS21775 ENOG4105NUP lyase containing HEAT-repeat HUU83_RS21800 ENOG4105EFX secretion protein, HlyD family HUU83_RS21805 ENOG4105FP6 Protein of unknown function (DUF3302) HUU83_RS21810 ENOG4105CTS PTS system mannitol-specific HUU83_RS21820 ENOG4105E61 Mannitol repressor protein HUU83_RS21830 ENOG4108YYI Protein of unknown function (DUF2810) HUU83_RS21835 ENOG4108WY4 inner membrane lipoprotein HUU83_RS21840 ENOG4105EUR Domain-Containing protein HUU83_RS21845 ENOG4105DAA L-lactate HUU83_RS21850 ENOG41073TP transcriptional regulator HUU83_RS21860 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) HUU83_RS21865 ENOG4105D7W serine acetyltransferase HUU83_RS21880 ENOG4105VW4 glutaredoxin 3 HUU83_RS21885 ENOG4107YZP Rhodanese domain protein HUU83_RS21895 ENOG41063SB peptidase HUU83_RS21900 ENOG4105PXI polysaccharide deacetylase HUU83_RS21905 ENOG4105K64 Glycosyl transferase, family 2 HUU83_RS21915 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) HUU83_RS21925 ENOG4105XA0 heptosyltransferase ii HUU83_RS21930 ENOG4105D16 lipopolysaccharide heptosyltransferase i HUU83_RS21935 ENOG41068PG O-Antigen polymerase HUU83_RS21940 ENOG4105K64 Glycosyl transferase, family 2 HUU83_RS21945 ENOG4105X1N Glycosyl transferase family 8 HUU83_RS21955 ENOG4105X1N Glycosyl transferase family 8 HUU83_RS21960 ENOG4106AH0 Glycosyl Transferase HUU83_RS21965 ENOG4107543 (lipo)polysaccharide HUU83_RS21970 ENOG4107RJ7 Glycosyl transferase (Group 1 HUU83_RS21975 ENOG4105DKP glycosyl transferase, family 9 HUU83_RS21980 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase HUU83_RS22000 ENOG4105KDC 50s ribosomal protein l28 HUU83_RS22010 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase HUU83_RS22015 ENOG4108Z1K This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) HUU83_RS22035 ENOG4105DSJ YicC domain protein HUU83_RS22040 ENOG4105F5P DNA-damage-inducible protein d HUU83_RS22045 ENOG4105EN6 Membrane HUU83_RS22055 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) HUU83_RS22065 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) HUU83_RS22070 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase HUU83_RS22075 ENOG4105CB5 ATP-dependent DNA helicase recG HUU83_RS22085 ENOG4105D6U Sodium Glutamate Symporter HUU83_RS22090 ENOG4105C2W permease HUU83_RS22095 ENOG4105JV1 AsmA family HUU83_RS22100 ENOG4105CJQ hydrolase, family 31 HUU83_RS22105 ENOG4105CT4 transporter HUU83_RS22120 ENOG4105S8Q sugar efflux transporter HUU83_RS22125 ENOG4108UZ3 Transporter HUU83_RS22130 ENOG4105D01 (LipO)protein HUU83_RS22135 ENOG4105T8A Uncharacterized protein YicS HUU83_RS22145 ENOG4108SAJ Protein of unknown function (DUF1198) HUU83_RS22150 ENOG4105C7N Xanthine uracil vitamin C permease HUU83_RS22155 ENOG4105CPN adenine deaminase HUU83_RS22160 ENOG4105CXY transporter HUU83_RS22165 ENOG4105CXY transporter HUU83_RS22170 ENOG4105BZU Histidine kinase HUU83_RS22175 ENOG4108KX4 response regulator HUU83_RS22180 ENOG4105M71 acetolactate synthase 1 regulatory subunit HUU83_RS22185 ENOG4105C7K acetolactate synthase HUU83_RS22200 ENOG4105E5M Multidrug resistance protein D HUU83_RS22205 ENOG4105J13 transcriptional regulator HUU83_RS22210 ENOG4105JP4 Inner membrane protein yidG HUU83_RS22215 ENOG4105VG5 Membrane HUU83_RS22220 ENOG4106DRA Inner membrane protein YidI HUU83_RS22225 ENOG4105CBG Sulfatase HUU83_RS22230 ENOG4107RUZ Sss sodium solute transporter superfamily HUU83_RS22235 ENOG4108AHD Transcriptional regulator HUU83_RS22245 ENOG4105CI1 PTS System HUU83_RS22250 ENOG4105FDP GntR family transcriptional regulator HUU83_RS22270 ENOG4105R2A (LipO)protein HUU83_RS22275 ENOG4105D99 atp gtp-binding protein HUU83_RS22285 ENOG4105DJB Major Facilitator Superfamily HUU83_RS22295 ENOG4108RTU Aldolase HUU83_RS22300 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 HUU83_RS22305 ENOG4105EMF GntR family transcriptional regulator HUU83_RS22310 ENOG410657R replicase EC 2.7 HUU83_RS22315 ENOG410667J hydrolase HUU83_RS22320 ENOG4105VP5 Bacterial protein of unknown function (DUF937) HUU83_RS22325 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HUU83_RS22335 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) HUU83_RS22350 ENOG4105VG0 50S ribosomal protein l34 HUU83_RS22385 ENOG4108P6C Tryptophan transporter of low affinity HUU83_RS22400 ENOG4105E8Q phosphopantetheinyl transferase HUU83_RS22405 ENOG4108YYH Nadph-dependent fmn reductase HUU83_RS22410 ENOG4105C7N Xanthine uracil vitamin C permease HUU83_RS22415 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 HUU83_RS22425 ENOG4106611 bacteriocin immunity HUU83_RS22430 ENOG4107VKM 6-phosphogluconolactonase HUU83_RS22435 ENOG4105DYC esterase HUU83_RS22445 ENOG4105CS2 ec 3.2.1.21 HUU83_RS22450 ENOG4105C5Y PTS System HUU83_RS22455 ENOG4105CID antiterminator HUU83_RS22460 ENOG4108UTW Plays a role in the regulation of phosphate uptake HUU83_RS22465 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) HUU83_RS22470 ENOG4105E2Z phosphate ABC transporter (Permease HUU83_RS22475 ENOG4105C8U phosphate abc transporter HUU83_RS22480 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) HUU83_RS22490 ENOG4105CW0 outer membrane usher protein HUU83_RS22500 ENOG4108RQP Major type 1 subunit fimbrin HUU83_RS22575 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) HUU83_RS22625 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation HUU83_RS22640 ENOG4105QTB Flavodoxin HUU83_RS22645 ENOG4108VVK transcriptional Regulator, AsnC HUU83_RS22675 ENOG4105C2J ABC transporter HUU83_RS22680 ENOG4105CNN ABC, transporter HUU83_RS22685 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator HUU83_RS22690 ENOG4108RVA ribokinase HUU83_RS22695 ENOG4105ETE Transcriptional regulator (LacI family HUU83_RS22700 ENOG4105C0R drug resistance transporter emrb qaca subfamily HUU83_RS22705 ENOG4107EJG GntR family transcriptional regulator HUU83_RS22745 ENOG4108WFC UPF0438 protein yifE HUU83_RS22750 ENOG4105C0P Mg chelatase subunit ChlI HUU83_RS22770 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit HUU83_RS22775 ENOG4105CM2 brancheD-chain amino acid aminotransferase HUU83_RS22785 ENOG4105C7B Threonine dehydratase HUU83_RS22790 ENOG4105EMY transcriptional regulator HUU83_RS22800 ENOG4105KQ5 peptidylprolyl cis-trans isomerase HUU83_RS22810 ENOG4105C4R Atp-dependent dna helicase HUU83_RS22835 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) HUU83_RS22840 ENOG4105ESV Glycosyl transferase, family 4 HUU83_RS22845 ENOG4105SFE lipopolysaccharide biosynthesis protein HUU83_RS22850 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase HUU83_RS22855 ENOG4107QQG Dehydrogenase HUU83_RS22860 ENOG4105C1B dTDP-glucose 4-6-dehydratase HUU83_RS22865 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) HUU83_RS22870 ENOG4108WJ1 acetyltransferase HUU83_RS22875 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase HUU83_RS22880 ENOG4105EGZ biosynthesis protein HUU83_RS22900 ENOG4105C85 amino acid HUU83_RS22925 ENOG4105C4X radical SAM domain protein HUU83_RS22930 ENOG4105ENH Sulfatase HUU83_RS22935 ENOG410601J HemY protein HUU83_RS22940 ENOG4105ECF c-methyltransferase HUU83_RS22945 ENOG41076E6 Uroporphyrinogen-III Synthase HUU83_RS22955 ENOG4107T0K Adenylate cyclase HUU83_RS22980 ENOG4105S7Z (LipO)protein HUU83_RS22990 ENOG4105CT0 Protein of unknown function, DUF484 HUU83_RS23000 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant HUU83_RS23005 ENOG4105C4R Atp-dependent dna helicase HUU83_RS23010 ENOG4108T58 Mg2 transport protein CorA HUU83_RS23015 ENOG4107QUT magnesium and cobalt transport protein CorA HUU83_RS23030 ENOG4107QUT magnesium and cobalt transport protein CorA HUU83_RS23040 ENOG4105FR1 rard protein HUU83_RS23045 ENOG4108VUY thioesterase Superfamily protein HUU83_RS23050 ENOG4105HDD phospholipase HUU83_RS23055 ENOG4105C9U ATP-dependent DNA helicase RecQ HUU83_RS23060 ENOG4105CCF Lysine exporter protein (Lyse ygga) HUU83_RS23065 ENOG410829K Lysine exporter protein (Lyse ygga) HUU83_RS23070 ENOG4108EUD Lysophospholipase HUU83_RS23075 ENOG4105DQF Hydrolase HUU83_RS23080 ENOG4105EMK carboxylate amino acid amine transporter HUU83_RS23085 ENOG4105DZ2 Transcriptional regulator HUU83_RS23095 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) HUU83_RS23100 ENOG4108I5U Uridine phosphorylase HUU83_RS23105 ENOG4105CGY Dna recombination protein HUU83_RS23115 ENOG4105JC1 sterol-binding domain protein HUU83_RS23125 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) HUU83_RS23130 ENOG4105X8U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity) HUU83_RS23135 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) HUU83_RS23145 ENOG4105MDZ Transcriptional activator rfaH HUU83_RS23150 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) HUU83_RS23155 ENOG4108EX3 reductase HUU83_RS23160 ENOG4105CHU acetyl-coa acetyltransferase HUU83_RS23165 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase HUU83_RS23175 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein HUU83_RS23180 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) HUU83_RS23185 ENOG4108RR8 protoporphyrinogen oxidase HUU83_RS23215 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b HUU83_RS23220 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) HUU83_RS23225 ENOG4105PC1 Conserved Protein HUU83_RS23230 ENOG4105E27 serine threonine protein kinase HUU83_RS23235 ENOG4108Z33 Thiol disulfide Interchange Protein HUU83_RS23245 ENOG4106HNH Acyl-transferase HUU83_RS23250 ENOG4105C2M dna polymerase I HUU83_RS23265 ENOG4105D4P Coproporphyrinogen iii oxidase HUU83_RS23270 ENOG4106FIY HUU83_RS23275 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HUU83_RS23280 ENOG4105CUX Signal transduction histidine kinase HUU83_RS23285 ENOG4105C5F glutamine synthetase HUU83_RS23290 ENOG4105CI3 gtp-binding protein typa HUU83_RS23295 ENOG4108K85 Transcriptional regulator HUU83_RS23300 ENOG4108KHF Resistance protein HUU83_RS23305 ENOG4105R9B Major Facilitator HUU83_RS23310 ENOG4108KUC Outer membrane channel protein that allows an efficient diffusion of low-molecular-weight solutes such as small sugars and tetraglycine. However, the specific substrate recognized by the OmpL channel is HUU83_RS23315 ENOG4105CT4 transporter HUU83_RS23320 ENOG4105CT4 transporter HUU83_RS23325 ENOG4105CJQ hydrolase, family 31 HUU83_RS23330 ENOG4107WI4 Aldose-1-epimerase HUU83_RS23335 ENOG4107QKS N-acylglucosamine 2-epimerase HUU83_RS23340 ENOG4105D2M Aldolase HUU83_RS23345 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase HUU83_RS23350 ENOG4108MGF sugar kinase HUU83_RS23355 ENOG4105E98 transcriptional regulator DeoR family HUU83_RS23360 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 HUU83_RS23375 ENOG4105SUU thioesterase domain HUU83_RS23385 ENOG4105W2W Cytotoxic translational repressor of toxin-antitoxin stability system HUU83_RS23400 ENOG41068KX affects formate dehydrogenase-N HUU83_RS23410 ENOG4108MG3 formate dehydrogenase HUU83_RS23415 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HUU83_RS23430 ENOG4108V87 frv operon regulatory protein HUU83_RS23435 ENOG4106C3V frv operon regulatory protein HUU83_RS23440 ENOG4105CN9 Peptidase m42 family protein HUU83_RS23445 ENOG4105DM4 PTS System HUU83_RS23450 ENOG41064BA PTS system, fructose-specific, IIA component HUU83_RS23460 ENOG4105C9J Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde (By similarity) HUU83_RS23495 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) HUU83_RS23505 ENOG4108RPX mosc domain containing protein HUU83_RS23510 ENOG4105E0F Histidine kinase HUU83_RS23515 ENOG4105E3W Two component transcriptional regulator (Winged helix family HUU83_RS23520 ENOG4105FMW periplasmic HUU83_RS23525 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) HUU83_RS23605 ENOG4105UZW Tail fiber assembly protein HUU83_RS23615 ENOG4108X9F tail fiber protein HUU83_RS23690 ENOG4105IM0 capsid protein HUU83_RS23700 ENOG4105F7J membrane-bound serine protease HUU83_RS23710 ENOG4107DE1 head-to-tail joining protein HUU83_RS23715 ENOG4105UZW Tail fiber assembly protein HUU83_RS23720 ENOG4105FKG DNA packaging protein HUU83_RS23745 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 HUU83_RS23750 ENOG4105KUS lysozyme HUU83_RS23855 ENOG4105D7V transposase HUU83_RS23980 ENOG4105KF5 hemolysin expression-modulating protein HUU83_RS23985 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) HUU83_RS24000 ENOG4105KK6 nuclease HUU83_RS24055 ENOG4107QHF type ii secretion system protein e HUU83_RS24085 ENOG4108EHY type IV secretion system HUU83_RS24105 ENOG4105EJX conjugal transfer ATPase HUU83_RS24145 ENOG4105K4U addiction module toxin, RelE StbE family HUU83_RS24240 ENOG4106CQM replication HUU83_RS24275 ENOG4108BUD transposase HUU83_RS24285 ENOG4108BUD transposase HUU83_RS24310 ENOG4108BUD transposase HUU83_RS24330 ENOG4108BUD transposase HUU83_RS24375 ENOG41073YN Protein of unknown function (DUF1380) HUU83_RS24380 ENOG4106JQ7 HUU83_RS24450 ENOG41074AV Hok/gef family HUU83_RS24670 ENOG4107CBI conjugal transfer fertility inhibition protein HUU83_RS24695 ENOG4107AVE This protein is involved in the determination of copy number in gene replication. It binds to the repA promoter thus inhibiting the synthesis of the mRNA for the initiator protein repA (By similarity) HUU83_RS24725 ENOG4108NC2 Outer membrane protease HUU83_RS24765 ENOG4105QYK bacteriophage lambda Bor protein homolog HUU83_RS24790 ENOG4105E93 esterase HUU83_RS24795 ENOG4105NIV Esterase HUU83_RS24800 ENOG4107RNH Outer membrane receptor FepA HUU83_RS24915 ENOG4108KTG Membrane protein, drug metabolite transporter HUU83_RS24940 ENOG4108BUD transposase HUU83_RS24980 ENOG4108BUD transposase HUU83_RS25000 ENOG4108BUD transposase HUU83_RS25015 ENOG4105EUV Phenol 2-monooxygenase HUU83_RS25045 ENOG4108BUD transposase HUU83_RS25065 ENOG4108BUD transposase HUU83_RS25120 ENOG4106CQM replication HUU83_RS25155 ENOG4107CBI conjugal transfer fertility inhibition protein HUU83_RS25160 ENOG4107U2T alpha beta HUU83_RS25175 ENOG4105VGJ Virulence-associated protein HUU83_RS25180 ENOG4105M0J Toxic component of a toxin-antitoxin (TA) module. A HUU83_RS25360 ENOG41074AV Hok/gef family HUU83_RS25420 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) HUU83_RS25425 ENOG4105DUU IucA IucC family protein HUU83_RS25445 ENOG41082CG Protein CrcB homolog HUU83_RS25460 ENOG4105CC5 ABC transporter HUU83_RS25465 ENOG4105CC5 ABC transporter HUU83_RS25470 ENOG4105DIK (ABC) transporter