locus-tag	class	description
AM440_RS00010	COG0523	cobalamin synthesis protein
AM440_RS00015	COG0246	Mannitol dehydrogenase
AM440_RS00030	COG2814	Major facilitator Superfamily
AM440_RS00035	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM440_RS00035	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM440_RS00040	COG1105	Belongs to the carbohydrate kinase PfkB family
AM440_RS00045	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AM440_RS00045	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM440_RS00045	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM440_RS00050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM440_RS00055	COG2313	pseudouridylate synthase activity
AM440_RS00060	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AM440_RS00065	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM440_RS00075	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AM440_RS00080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM440_RS00080	COG1522	sequence-specific DNA binding
AM440_RS00090	COG2855	membrane
AM440_RS00095	COG0583	DNA-binding transcription factor activity
AM440_RS00105	COG0833	amino acid
AM440_RS00115	COG4771	TonB-dependent receptor
AM440_RS00140	COG2311	Membrane
AM440_RS00150	COG1609	Transcriptional regulator
AM440_RS00155	COG1879	ABC-type sugar transport system periplasmic component
AM440_RS00160	COG1129	ABC transporter
AM440_RS00165	COG4211	Belongs to the binding-protein-dependent transport system permease family
AM440_RS00170	COG0167	dihydroorotate dehydrogenase activity
AM440_RS00170	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AM440_RS00175	COG0493	'glutamate synthase
AM440_RS00185	COG2949	membrane
AM440_RS00195	COG1346	cytolysis
AM440_RS00205	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM440_RS00230	COG1028	Short-chain dehydrogenase reductase Sdr
AM440_RS00235	COG0586	Pfam SNARE associated Golgi protein
AM440_RS00245	COG1686	Belongs to the peptidase S11 family
AM440_RS00250	COG0277	FAD linked oxidase domain protein
AM440_RS00255	COG1472	Belongs to the glycosyl hydrolase 3 family
AM440_RS00260	COG1732	Glycine betaine
AM440_RS00265	COG1174	glycine betaine transport
AM440_RS00270	COG1125	glycine betaine transport
AM440_RS00275	COG1174	glycine betaine transport
AM440_RS00285	COG0789	Transcriptional regulator
AM440_RS00290	COG3275	phosphorelay sensor kinase activity
AM440_RS00295	COG3279	Response regulator of the LytR AlgR family
AM440_RS00300	COG4807	Protein conserved in bacteria
AM440_RS00305	COG4808	Protein conserved in bacteria
AM440_RS00310	COG4715	Zinc finger, swim domain protein
AM440_RS00315	COG3552	Protein containing von Willebrand factor type A (VWA) domain
AM440_RS00325	COG0714	Associated with various cellular activities
AM440_RS00335	COG3831	ATPase activity
AM440_RS00350	COG0489	protein tyrosine kinase activity
AM440_RS00365	COG3539	Fimbrial protein
AM440_RS00370	COG3121	Chaperone
AM440_RS00375	COG3188	usher protein
AM440_RS00390	COG3539	Fimbrial protein
AM440_RS00395	COG5455	response to cobalt ion
AM440_RS00400	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AM440_RS00415	COG0351	phosphomethylpyrimidine kinase
AM440_RS00420	COG3757	hydrolase, family 25
AM440_RS00425	COG2188	Transcriptional regulator
AM440_RS00430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM440_RS00435	COG1397	ADP-ribosylglycohydrolase
AM440_RS00440	COG2211	Major facilitator Superfamily
AM440_RS00445	COG1830	Aldolase
AM440_RS00460	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM440_RS00465	COG3414	Phosphotransferase system galactitol-specific IIB component
AM440_RS00470	COG3775	system Galactitol-specific IIC component
AM440_RS00475	COG1063	alcohol dehydrogenase
AM440_RS00500	COG0826	peptidase U32
AM440_RS00510	COG0745	RESPONSE REGULATOR receiver
AM440_RS00515	COG2205	protein histidine kinase activity
AM440_RS00545	COG4245	von Willebrand factor, type A
AM440_RS00550	COG0631	protein serine/threonine phosphatase activity
AM440_RS00555	COG3779	Protein conserved in bacteria
AM440_RS00560	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
AM440_RS00565	COG0443	Heat shock 70 kDa protein
AM440_RS00570	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AM440_RS00575	COG5002	protein histidine kinase activity
AM440_RS00575	COG3447	MASE1 domain protein
AM440_RS00575	COG5001	Diguanylate cyclase
AM440_RS00580	COG0572	uridine kinase
AM440_RS00590	COG2982	Protein involved in outer membrane biogenesis
AM440_RS00595	COG1253	flavin adenine dinucleotide binding
AM440_RS00600	COG1596	polysaccharide export
AM440_RS00605	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AM440_RS00610	COG0489	protein tyrosine kinase activity
AM440_RS00610	COG3206	protein involved in exopolysaccharide biosynthesis
AM440_RS00615	COG0463	Glycosyl transferase, family 2
AM440_RS00620	COG1045	serine acetyltransferase
AM440_RS00625	COG0438	transferase activity, transferring glycosyl groups
AM440_RS00635	COG1216	Glycosyl transferase, family 2
AM440_RS00640	COG0110	maltose O-acetyltransferase activity
AM440_RS00645	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AM440_RS00650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM440_RS00655	COG1051	belongs to the nudix hydrolase family
AM440_RS00660	COG0297	glycogen (starch) synthase activity
AM440_RS00665	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AM440_RS00665	COG0662	Cupin 2, conserved barrel domain protein
AM440_RS00670	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AM440_RS00675	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AM440_RS00680	COG2244	polysaccharide biosynthetic process
AM440_RS00690	COG2327	Polysaccharide pyruvyl transferase
AM440_RS00695	COG0438	transferase activity, transferring glycosyl groups
AM440_RS00705	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AM440_RS00780	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AM440_RS00810	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AM440_RS00815	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AM440_RS00815	COG0131	Imidazoleglycerol-phosphate dehydratase
AM440_RS00825	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AM440_RS00845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM440_RS00850	COG0583	DNA-binding transcription factor activity
AM440_RS00855	COG0531	amino acid
AM440_RS00860	COG2391	methyltransferase activity
AM440_RS00865	COG0425	Belongs to the sulfur carrier protein TusA family
AM440_RS00870	COG2925	Exonuclease
AM440_RS00875	COG1686	Belongs to the peptidase S11 family
AM440_RS00885	COG1289	transmembrane transporter activity
AM440_RS00905	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
AM440_RS00920	COG1376	ErfK ybiS ycfS ynhG family protein
AM440_RS00930	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM440_RS00935	COG3414	Phosphotransferase system galactitol-specific IIB component
AM440_RS00940	COG3775	system Galactitol-specific IIC component
AM440_RS00945	COG0698	ribose 5-phosphate isomerase
AM440_RS00950	COG1349	DNA-binding transcription factor activity
AM440_RS00960	COG3414	Phosphotransferase system galactitol-specific IIB component
AM440_RS00965	COG3775	system Galactitol-specific IIC component
AM440_RS00970	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AM440_RS00975	COG1028	Short-chain dehydrogenase reductase Sdr
AM440_RS00980	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AM440_RS01005	COG3209	COG3209 Rhs family protein
AM440_RS01040	COG0583	DNA-binding transcription factor activity
AM440_RS01045	COG0583	DNA-binding transcription factor activity
AM440_RS01055	COG0534	Mate efflux family protein
AM440_RS01070	COG0217	transcriptional regulatory protein
AM440_RS01075	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AM440_RS01080	COG0477	Major facilitator Superfamily
AM440_RS01090	COG1388	LysM domain
AM440_RS01090	COG1470	cell adhesion involved in biofilm formation
AM440_RS01130	COG3038	cytochrome b561
AM440_RS01135	COG3443	Belongs to the bacterial solute-binding protein 9 family
AM440_RS01150	COG2351	hydroxyisourate hydrolase activity
AM440_RS01165	COG0745	RESPONSE REGULATOR receiver
AM440_RS01170	COG2205	protein histidine kinase activity
AM440_RS01185	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AM440_RS01195	COG1418	mRNA catabolic process
AM440_RS01200	COG0270	DNA (cytosine-5-)-methyltransferase activity
AM440_RS01205	COG3727	T/G mismatch-specific endonuclease activity
AM440_RS01210	COG0697	spore germination
AM440_RS01215	COG2354	Protein conserved in bacteria
AM440_RS01220	COG5475	Uncharacterized small protein (DUF2158)
AM440_RS01255	COG2197	response regulator
AM440_RS01260	COG1684	flagellar biosynthetic protein fliR
AM440_RS01265	COG1987	bacterial-type flagellum assembly
AM440_RS01270	COG1338	Plays a role in the flagellum-specific transport system
AM440_RS01275	COG3190	flagellar
AM440_RS01280	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AM440_RS01285	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AM440_RS01290	COG1580	Controls the rotational direction of flagella during chemotaxis
AM440_RS01295	COG3144	bacterial-type flagellum assembly
AM440_RS01300	COG2882	bacterial-type flagellum organization
AM440_RS01305	COG1157	protein secretion by the type III secretion system
AM440_RS01310	COG1317	bacterial-type flagellum organization
AM440_RS01315	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AM440_RS01320	COG1766	The M ring may be actively involved in energy transduction
AM440_RS01345	COG2135	peptidase activity
AM440_RS01350	COG0425	Belongs to the sulfur carrier protein TusA family
AM440_RS01355	COG2391	methyltransferase activity
AM440_RS01370	COG0366	Alpha amylase catalytic
AM440_RS01380	COG1516	flagellar protein fliS
AM440_RS01385	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AM440_RS01400	COG1191	sigma factor activity
AM440_RS01410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM440_RS01420	COG0765	amino acid transport
AM440_RS01425	COG1126	abc transporter atp-binding protein
AM440_RS01430	COG2197	response regulator
AM440_RS01440	COG2197	response regulator
AM440_RS01470	COG3318	Belongs to the UPF0149 family
AM440_RS01470	COG3012	SEC-C Motif Domain Protein
AM440_RS01475	COG0814	amino acid
AM440_RS01485	COG1528	Iron-storage protein
AM440_RS01505	COG1528	Iron-storage protein
AM440_RS01515	COG1879	ABC-type sugar transport system periplasmic component
AM440_RS01520	COG1129	ABC transporter
AM440_RS01525	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM440_RS01530	COG1877	trehalose-phosphatase activity
AM440_RS01540	COG0589	response to stress
AM440_RS01555	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AM440_RS01560	COG1360	Flagellar Motor Protein
AM440_RS01565	COG2198	Histidine kinase
AM440_RS01565	COG0643	Histidine kinase
AM440_RS01570	COG0835	chemotaxis
AM440_RS01575	COG0840	transmembrane signaling receptor activity
AM440_RS01580	COG0840	transmembrane signaling receptor activity
AM440_RS01585	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AM440_RS01595	COG0745	RESPONSE REGULATOR receiver
AM440_RS01600	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AM440_RS01605	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AM440_RS01610	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AM440_RS01620	COG3755	Protein conserved in bacteria
AM440_RS01635	COG3102	Protein conserved in bacteria
AM440_RS01645	COG3005	denitrification pathway
AM440_RS01650	COG0243	molybdopterin cofactor binding
AM440_RS01665	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AM440_RS01670	COG1801	Protein of unknown function DUF72
AM440_RS01675	COG1335	isochorismatase
AM440_RS01685	COG0494	nUDIX hydrolase
AM440_RS01690	COG0217	transcriptional regulatory protein
AM440_RS01720	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM440_RS01730	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AM440_RS01735	COG0739	heme binding
AM440_RS01740	COG1560	Kdo2-lipid A biosynthetic process
AM440_RS01745	COG0469	pyruvate kinase activity
AM440_RS01750	COG1737	Transcriptional regulator
AM440_RS01755	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AM440_RS01760	COG0129	dihydroxy-acid dehydratase activity
AM440_RS01765	COG0800	Aldolase
AM440_RS01775	COG3141	response to X-ray
AM440_RS01785	COG2979	Protein of unknown function (DUF533)
AM440_RS01795	COG1770	oligopeptidase
AM440_RS01800	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM440_RS01805	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM440_RS01815	COG2372	response to copper ion
AM440_RS01820	COG1276	copper resistance
AM440_RS01830	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AM440_RS01850	COG3008	intermembrane lipid transfer
AM440_RS01855	COG2995	paraquat-inducible protein a
AM440_RS01860	COG1956	GAF domain-containing protein
AM440_RS01870	COG0793	Belongs to the peptidase S41A family
AM440_RS01880	COG2814	Major facilitator Superfamily
AM440_RS01885	COG1414	Transcriptional regulator
AM440_RS01920	COG2226	methyltransferase
AM440_RS01940	COG3716	PTS system mannose fructose sorbose family IID component
AM440_RS01945	COG3715	PTS system
AM440_RS01950	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM440_RS01950	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM440_RS01965	COG1253	flavin adenine dinucleotide binding
AM440_RS01970	COG2200	EAL domain
AM440_RS01975	COG1760	l-serine dehydratase
AM440_RS01985	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AM440_RS02010	COG0251	oxidation-reduction process
AM440_RS02015	COG1199	ATP-dependent helicase activity
AM440_RS02020	COG1214	PFAM Peptidase M22, glycoprotease
AM440_RS02025	COG3065	identical protein binding
AM440_RS02030	COG0318	PFAM AMP-dependent synthetase and ligase
AM440_RS02035	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AM440_RS02040	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM440_RS02045	COG4638	Rieske (2fe-2S)
AM440_RS02050	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM440_RS02055	COG0473	3-isopropylmalate dehydrogenase activity
AM440_RS02060	COG0583	DNA-binding transcription factor activity
AM440_RS02070	COG3615	Tellurite resistance protein tehB
AM440_RS02080	COG2261	transglycosylase associated protein
AM440_RS02095	COG2203	Gaf domain
AM440_RS02095	COG2199	diguanylate cyclase activity
AM440_RS02100	COG3042	response to heat
AM440_RS02105	COG3189	MarR family transcriptional regulator
AM440_RS02110	COG2807	transmembrane transport
AM440_RS02115	COG2207	Transcriptional regulator
AM440_RS02130	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AM440_RS02135	COG2199	diguanylate cyclase activity
AM440_RS02140	COG2199	diguanylate cyclase activity
AM440_RS02150	COG2766	serine protein kinase
AM440_RS02155	COG3713	MltA-interacting MipA family protein
AM440_RS02160	COG0656	L-ascorbic acid biosynthetic process
AM440_RS02165	COG0676	glucose-6-phosphate 1-epimerase activity
AM440_RS02170	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AM440_RS02180	COG3139	Protein of unknown function (DUF1315)
AM440_RS02185	COG1063	alcohol dehydrogenase
AM440_RS02190	COG2271	Major facilitator Superfamily
AM440_RS02195	COG1063	alcohol dehydrogenase
AM440_RS02210	COG0191	fructose-bisphosphate aldolase activity
AM440_RS02215	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM440_RS02220	COG0667	Aldo Keto reductase
AM440_RS02225	COG1349	DNA-binding transcription factor activity
AM440_RS02230	COG2814	Major facilitator Superfamily
AM440_RS02235	COG1335	isochorismatase
AM440_RS02240	COG0252	asparaginase activity
AM440_RS02245	COG0616	signal peptide processing
AM440_RS02255	COG0778	Nitroreductase
AM440_RS02270	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AM440_RS02280	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AM440_RS02290	COG0494	nUDIX hydrolase
AM440_RS02295	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AM440_RS02300	COG2897	thiosulfate sulfurtransferase activity
AM440_RS02305	COG4136	ATPase activity
AM440_RS02310	COG4135	transport system, permease component
AM440_RS02315	COG4134	Bacterial extracellular solute-binding protein
AM440_RS02320	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM440_RS02325	COG0398	Pfam SNARE associated Golgi protein
AM440_RS02335	COG0398	Pfam SNARE associated Golgi protein
AM440_RS02340	COG0708	Exodeoxyribonuclease III
AM440_RS02375	COG3678	ATP-independent chaperone mediated protein folding
AM440_RS02385	COG0322	excinuclease ABC activity
AM440_RS02395	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM440_RS02405	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM440_RS02410	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM440_RS02415	COG1447	Phosphotransferase system cellobiose-specific component IIA
AM440_RS02420	COG1917	Cupin 2, conserved barrel domain protein
AM440_RS02420	COG2169	Transcriptional regulator
AM440_RS02425	COG1486	melibiose metabolic process
AM440_RS02435	COG0753	catalase activity
AM440_RS02450	COG1823	symporter activity
AM440_RS02455	COG1988	membrane-bound metal-dependent
AM440_RS02460	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM440_RS02470	COG3001	Fructosamine kinase
AM440_RS02480	COG1105	Belongs to the carbohydrate kinase PfkB family
AM440_RS02485	COG3137	Salt-induced outer membrane protein
AM440_RS02530	COG0072	phenylalanine-tRNA ligase activity
AM440_RS02530	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM440_RS02545	COG0386	Belongs to the glutathione peroxidase family
AM440_RS02555	COG0791	NLP P60 protein
AM440_RS02560	COG2200	EAL domain
AM440_RS02570	COG4256	Hemin uptake protein
AM440_RS02575	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM440_RS02590	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM440_RS02590	COG0574	Belongs to the PEP-utilizing enzyme family
AM440_RS02595	COG0318	PFAM AMP-dependent synthetase and ligase
AM440_RS02600	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AM440_RS02605	COG0644	oxidoreductase
AM440_RS02610	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AM440_RS02615	COG2086	electron transfer activity
AM440_RS02625	COG1917	Cupin 2, conserved barrel domain protein
AM440_RS02625	COG2207	Transcriptional regulator
AM440_RS02630	COG1960	acyl-CoA dehydrogenase activity
AM440_RS02635	COG4670	ketone body catabolic process
AM440_RS02650	COG2271	Major facilitator Superfamily
AM440_RS02655	COG0738	Major facilitator superfamily
AM440_RS02670	COG0628	permease
AM440_RS02680	COG0247	lactate metabolic process
AM440_RS02680	COG0277	FAD linked oxidase domain protein
AM440_RS02685	COG2050	protein possibly involved in aromatic compounds catabolism
AM440_RS02695	COG0316	Belongs to the HesB IscA family
AM440_RS02700	COG0719	Fe-S assembly protein
AM440_RS02705	COG0396	ATPase activity
AM440_RS02710	COG0719	Fe-S assembly protein
AM440_RS02725	COG1376	ErfK ybiS ycfS ynhG family protein
AM440_RS02730	COG4238	major outer membrane lipoprotein
AM440_RS02735	COG0469	pyruvate kinase activity
AM440_RS02745	COG0437	4 iron, 4 sulfur cluster binding
AM440_RS02750	COG2414	aldehyde ferredoxin oxidoreductase
AM440_RS02760	COG0437	4 iron, 4 sulfur cluster binding
AM440_RS02765	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
AM440_RS02775	COG4529	Protein conserved in bacteria
AM440_RS02795	COG3468	outer membrane autotransporter barrel domain protein
AM440_RS02805	COG0307	riboflavin synthase, alpha
AM440_RS02810	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AM440_RS02815	COG2814	Major facilitator Superfamily
AM440_RS02820	COG0583	DNA-binding transcription factor activity
AM440_RS02840	COG2814	Major facilitator Superfamily
AM440_RS02845	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AM440_RS02850	COG0791	NLP P60 protein
AM440_RS02855	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AM440_RS02860	COG1201	RNA secondary structure unwinding
AM440_RS02870	COG0346	lactoylglutathione lyase activity
AM440_RS02875	COG1902	pentaerythritol trinitrate reductase activity
AM440_RS02880	COG1309	transcriptional regulator
AM440_RS02885	COG3313	Fe-S protein
AM440_RS02890	COG4989	oxidoreductase activity
AM440_RS02895	COG2032	superoxide dismutase activity
AM440_RS02900	COG1289	transmembrane transporter activity
AM440_RS02905	COG1566	PFAM secretion protein HlyD family protein
AM440_RS02920	COG3133	Outer membrane lipoprotein
AM440_RS02930	COG3895	Periplasmic Protein
AM440_RS02945	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AM440_RS02950	COG0625	glutathione transferase activity
AM440_RS02955	COG3104	oligopeptide transport
AM440_RS02965	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AM440_RS02975	COG4659	FMN binding
AM440_RS03020	COG0673	inositol 2-dehydrogenase activity
AM440_RS03030	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AM440_RS03035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM440_RS03035	COG1263	PTS System
AM440_RS03040	COG1609	Transcriptional regulator
AM440_RS03045	COG1028	Short-chain dehydrogenase reductase Sdr
AM440_RS03050	COG1309	transcriptional regulator
AM440_RS03055	COG3250	beta-galactosidase activity
AM440_RS03070	COG5339	Protein conserved in bacteria
AM440_RS03075	COG1482	cell wall glycoprotein biosynthetic process
AM440_RS03080	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AM440_RS03080	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AM440_RS03085	COG0114	fumarate hydratase activity
AM440_RS03095	COG2205	protein histidine kinase activity
AM440_RS03100	COG0745	RESPONSE REGULATOR receiver
AM440_RS03105	COG3136	membrane protein required for alginate biosynthesis
AM440_RS03115	COG0531	amino acid
AM440_RS03130	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AM440_RS03135	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AM440_RS03140	COG0628	permease
AM440_RS03155	COG3591	Belongs to the peptidase S1B family
AM440_RS03175	COG2814	Major facilitator Superfamily
AM440_RS03180	COG0583	DNA-binding transcription factor activity
AM440_RS03185	COG1940	carbohydrate kinase activity
AM440_RS03190	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AM440_RS03200	COG3381	protein complex oligomerization
AM440_RS03205	COG3302	dmso reductase anchor subunit
AM440_RS03210	COG0437	4 iron, 4 sulfur cluster binding
AM440_RS03215	COG0243	molybdopterin cofactor binding
AM440_RS03220	COG0243	molybdopterin cofactor binding
AM440_RS03235	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM440_RS03255	COG4948	Mandelate Racemase Muconate Lactonizing
AM440_RS03260	COG1063	alcohol dehydrogenase
AM440_RS03265	COG0477	Major facilitator Superfamily
AM440_RS03270	COG0246	Mannitol dehydrogenase
AM440_RS03280	COG1802	Transcriptional regulator
AM440_RS03285	COG4221	oxidoreductase activity
AM440_RS03290	COG0339	signal peptide processing
AM440_RS03295	COG1546	Belongs to the CinA family
AM440_RS03300	COG3111	PFAM Bacterial OB fold (BOF) protein
AM440_RS03305	COG3706	GGDEF domain
AM440_RS03315	COG2814	Major facilitator Superfamily
AM440_RS03320	COG0697	spore germination
AM440_RS03325	COG2188	Transcriptional regulator
AM440_RS03335	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM440_RS03340	COG1447	Phosphotransferase system cellobiose-specific component IIA
AM440_RS03355	COG2723	6-phospho-beta-galactosidase activity
AM440_RS03365	COG4977	sequence-specific DNA binding
AM440_RS03370	COG1846	Transcriptional regulator
AM440_RS03395	COG0583	DNA-binding transcription factor activity
AM440_RS03400	COG1012	belongs to the aldehyde dehydrogenase family
AM440_RS03405	COG2066	Belongs to the glutaminase family
AM440_RS03415	COG2199	diguanylate cyclase activity
AM440_RS03435	COG3781	membrane
AM440_RS03485	COG2911	Protein conserved in bacteria
AM440_RS03485	COG3210	domain, Protein
AM440_RS03490	COG1396	sequence-specific DNA binding
AM440_RS03495	COG3550	peptidyl-serine autophosphorylation
AM440_RS03565	COG3188	usher protein
AM440_RS03570	COG3539	Fimbrial protein
AM440_RS03575	COG3539	Fimbrial protein
AM440_RS03585	COG0243	molybdopterin cofactor binding
AM440_RS03600	COG3119	arylsulfatase activity
AM440_RS03605	COG0641	radical SAM
AM440_RS03610	COG4178	(ABC) transporter
AM440_RS03615	COG4771	TonB-dependent receptor
AM440_RS03620	COG0612	Peptidase, M16
AM440_RS03630	COG0076	glutamate decarboxylase activity
AM440_RS03635	COG0531	amino acid
AM440_RS03640	COG1649	PFAM Uncharacterised BCR, COG1649
AM440_RS03645	COG3706	GGDEF domain
AM440_RS03650	COG2199	diguanylate cyclase activity
AM440_RS03650	COG2200	EAL domain
AM440_RS03650	COG2202	Pas domain
AM440_RS03655	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AM440_RS03660	COG0747	negative chemotaxis
AM440_RS03665	COG0601	transmembrane transport
AM440_RS03670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM440_RS03675	COG0444	Belongs to the ABC transporter superfamily
AM440_RS03680	COG4608	Belongs to the ABC transporter superfamily
AM440_RS03685	COG1764	response to oxidative stress
AM440_RS03710	COG1064	alcohol dehydrogenase
AM440_RS03715	COG3093	addiction module antidote protein HigA
AM440_RS03720	COG2864	formate dehydrogenase
AM440_RS03725	COG0437	4 iron, 4 sulfur cluster binding
AM440_RS03735	COG0697	spore germination
AM440_RS03740	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AM440_RS03745	COG4886	Leucine-rich repeat (LRR) protein
AM440_RS03755	COG4886	Leucine-rich repeat (LRR) protein
AM440_RS03765	COG2223	nitrite transmembrane transporter activity
AM440_RS03770	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AM440_RS03775	COG1140	nitrate reductase beta subunit
AM440_RS03780	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AM440_RS03785	COG2181	nitrate reductase activity
AM440_RS03790	COG0384	phenazine biosynthesis protein PhzF
AM440_RS03795	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AM440_RS03800	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM440_RS03810	COG5433	transposase activity
AM440_RS03815	COG3209	COG3209 Rhs family protein
AM440_RS03830	COG1113	amino acid transport
AM440_RS03835	COG3391	amine dehydrogenase activity
AM440_RS03850	COG4772	TonB-dependent receptor
AM440_RS03855	COG1802	Transcriptional regulator
AM440_RS03860	COG2130	NADP-dependent
AM440_RS03870	COG1247	-acetyltransferase
AM440_RS03875	COG3238	Protein conserved in bacteria
AM440_RS03905	COG1177	transmembrane transport
AM440_RS03910	COG1176	ABC-type spermidine putrescine transport system, permease component I
AM440_RS03915	COG3842	ATPase activity
AM440_RS03920	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AM440_RS03925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM440_RS03930	COG1598	PFAM Uncharacterised protein family UPF0150
AM440_RS03945	COG0826	peptidase U32
AM440_RS03950	COG1396	sequence-specific DNA binding
AM440_RS03955	COG3135	benzoate transporter
AM440_RS03960	COG0675	Transposase, IS605 OrfB family
AM440_RS03975	COG0500	methyltransferase
AM440_RS03980	COG1275	C4-dicarboxylate transporter malic acid transport protein
AM440_RS03985	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM440_RS03990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM440_RS03995	COG2841	Protein conserved in bacteria
AM440_RS04015	COG5383	Protein conserved in bacteria
AM440_RS04020	COG0583	DNA-binding transcription factor activity
AM440_RS04025	COG0840	transmembrane signaling receptor activity
AM440_RS04040	COG3038	cytochrome b561
AM440_RS04045	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AM440_RS04050	COG1012	belongs to the aldehyde dehydrogenase family
AM440_RS04055	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AM440_RS04060	COG1643	Atp-dependent helicase
AM440_RS04070	COG0671	phosphoesterase, PA-phosphatase related
AM440_RS04070	COG2453	phosphatase
AM440_RS04075	COG2267	carboxylic ester hydrolase activity
AM440_RS04080	COG4589	Belongs to the CDS family
AM440_RS04085	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AM440_RS04095	COG0667	Aldo Keto reductase
AM440_RS04110	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM440_RS04115	COG3327	negative regulation of DNA-templated transcription, initiation
AM440_RS04120	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AM440_RS04125	COG0183	Belongs to the thiolase family
AM440_RS04130	COG2050	protein possibly involved in aromatic compounds catabolism
AM440_RS04135	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM440_RS04140	COG1024	Enoyl-CoA hydratase
AM440_RS04145	COG1024	Enoyl-CoA hydratase
AM440_RS04150	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM440_RS04155	COG2151	metal-sulfur cluster biosynthetic enzyme
AM440_RS04160	COG3396	Phenylacetate-CoA oxygenase
AM440_RS04165	COG3460	Phenylacetate-CoA oxygenase
AM440_RS04170	COG3396	Phenylacetate-CoA oxygenase
AM440_RS04175	COG1012	belongs to the aldehyde dehydrogenase family
AM440_RS04175	COG2030	dehydratase
AM440_RS04180	COG3733	amine oxidase
AM440_RS04185	COG1012	belongs to the aldehyde dehydrogenase family
AM440_RS04190	COG2207	Transcriptional regulator
AM440_RS04195	COG3784	Protein of unknown function (DUF1318)
AM440_RS04205	COG2911	Protein conserved in bacteria
AM440_RS04210	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AM440_RS04215	COG3187	Heat shock protein
AM440_RS04220	COG3042	response to heat
AM440_RS04225	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AM440_RS04225	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM440_RS04225	COG0674	pyruvate-flavodoxin oxidoreductase activity
AM440_RS04225	COG1013	pyruvate-flavodoxin oxidoreductase activity
AM440_RS04235	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AM440_RS04240	COG0589	response to stress
AM440_RS04250	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AM440_RS04255	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AM440_RS04260	COG5301	cellulose 1,4-beta-cellobiosidase activity
AM440_RS04280	COG1475	DNA binding
AM440_RS04290	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AM440_RS04300	COG1846	Transcriptional regulator
AM440_RS04315	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM440_RS04320	COG3723	Recombinational DNA repair protein, rece pathway
AM440_RS04330	COG3723	Recombinational DNA repair protein, rece pathway
AM440_RS04350	COG0582	viral genome integration into host DNA
AM440_RS04360	COG0513	Belongs to the DEAD box helicase family
AM440_RS04375	COG3706	GGDEF domain
AM440_RS04380	COG2840	Smr protein MutS2
AM440_RS04390	COG0583	DNA-binding transcription factor activity
AM440_RS04395	COG1473	amidohydrolase
AM440_RS04400	COG1473	amidohydrolase
AM440_RS04410	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AM440_RS04415	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM440_RS04420	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM440_RS04425	COG0589	response to stress
AM440_RS04430	COG3182	Iron-regulated membrane protein
AM440_RS04435	COG0668	transmembrane transport
AM440_RS04440	COG4166	transmembrane transport
AM440_RS04445	COG0583	DNA-binding transcription factor activity
AM440_RS04450	COG1073	alpha beta
AM440_RS04455	COG0702	epimerase
AM440_RS04460	COG2866	Carboxypeptidase
AM440_RS04465	COG4948	Mandelate Racemase Muconate Lactonizing
AM440_RS04470	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AM440_RS04475	COG3283	Transcriptional regulator of aromatic amino acids metabolism
AM440_RS04485	COG3106	COG3106 Predicted ATPase
AM440_RS04490	COG1609	Transcriptional regulator
AM440_RS04510	COG0366	Alpha amylase catalytic
AM440_RS04515	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AM440_RS04525	COG1983	PspC domain protein
AM440_RS04535	COG1842	Phage shock protein A
AM440_RS04540	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AM440_RS04545	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AM440_RS04550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM440_RS04555	COG1012	belongs to the aldehyde dehydrogenase family
AM440_RS04565	COG1917	Cupin 2, conserved barrel domain protein
AM440_RS04565	COG1396	sequence-specific DNA binding
AM440_RS04570	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AM440_RS04575	COG0174	glutamine synthetase
AM440_RS04580	COG0531	amino acid
AM440_RS04595	COG4166	transmembrane transport
AM440_RS04600	COG4168	peptide transport system, permease
AM440_RS04605	COG4171	peptide transport system, permease
AM440_RS04610	COG4172	Belongs to the ABC transporter superfamily
AM440_RS04615	COG4172	Belongs to the ABC transporter superfamily
AM440_RS04620	COG2852	Protein conserved in bacteria
AM440_RS04630	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AM440_RS04635	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM440_RS04635	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM440_RS04650	COG5001	Diguanylate cyclase
AM440_RS04660	COG1349	DNA-binding transcription factor activity
AM440_RS04670	COG0023	Translation Initiation Factor
AM440_RS04680	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AM440_RS04685	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AM440_RS04690	COG0671	phosphoesterase, PA-phosphatase related
AM440_RS04700	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AM440_RS04720	COG0583	DNA-binding transcription factor activity
AM440_RS04730	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AM440_RS04745	COG0616	signal peptide processing
AM440_RS04750	COG1028	Short-chain dehydrogenase reductase Sdr
AM440_RS04755	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
AM440_RS04760	COG1187	pseudouridine synthase activity
AM440_RS04770	COG0009	L-threonylcarbamoyladenylate synthase
AM440_RS04775	COG0613	PHP domain protein
AM440_RS04785	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AM440_RS04790	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AM440_RS04790	COG0512	Glutamine amidotransferase of anthranilate synthase
AM440_RS04795	COG0135	phosphoribosylanthranilate isomerase activity
AM440_RS04795	COG0134	indole-3-glycerol-phosphate synthase activity
AM440_RS04810	COG3729	General stress protein
AM440_RS04815	COG3685	Protein conserved in bacteria
AM440_RS04820	COG3685	Protein conserved in bacteria
AM440_RS04825	COG3047	cAMP biosynthetic process
AM440_RS04840	COG1607	acyl-coa hydrolase
AM440_RS04845	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AM440_RS04850	COG2350	Protein conserved in bacteria
AM440_RS04855	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM440_RS04875	COG4608	Belongs to the ABC transporter superfamily
AM440_RS04880	COG0444	Belongs to the ABC transporter superfamily
AM440_RS04885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM440_RS04890	COG0601	transmembrane transport
AM440_RS04895	COG4166	transmembrane transport
AM440_RS04905	COG2095	MarC family integral membrane protein
AM440_RS04910	COG1012	belongs to the aldehyde dehydrogenase family
AM440_RS04910	COG1454	alcohol dehydrogenase
AM440_RS04915	COG1435	thymidine kinase activity
AM440_RS04925	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AM440_RS04930	COG0745	RESPONSE REGULATOR receiver
AM440_RS04935	COG1752	Esterase of the alpha-beta hydrolase superfamily
AM440_RS04945	COG0788	formyltetrahydrofolate deformylase activity
AM440_RS04970	COG2181	nitrate reductase activity
AM440_RS04975	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AM440_RS04980	COG1140	nitrate reductase beta subunit
AM440_RS04985	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AM440_RS04990	COG2223	nitrite transmembrane transporter activity
AM440_RS05000	COG3850	Histidine kinase
AM440_RS05005	COG2197	response regulator
AM440_RS05010	COG4932	domain protein
AM440_RS05015	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AM440_RS05020	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AM440_RS05025	COG4572	Cation transport regulator
AM440_RS05030	COG0387	Pfam Sodium calcium exchanger
AM440_RS05050	COG2912	Transglutaminase-like superfamily
AM440_RS05055	COG3094	Invasion gene expression up-regulator, SirB
AM440_RS05060	COG2890	protein-(glutamine-N5) methyltransferase activity
AM440_RS05085	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AM440_RS05090	COG0659	secondary active sulfate transmembrane transporter activity
AM440_RS05105	COG0012	GTP binding
AM440_RS05120	COG3468	outer membrane autotransporter barrel domain protein
AM440_RS05125	COG3284	Transcriptional regulator
AM440_RS05130	COG2376	Dihydroxyacetone kinase
AM440_RS05135	COG1461	Dihydroxyacetone kinase
AM440_RS05140	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
AM440_RS05140	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM440_RS05140	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM440_RS05175	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
AM440_RS05190	COG1619	proteins homologs of microcin C7 resistance protein MccF
AM440_RS05200	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AM440_RS05210	COG2719	SpoVR family
AM440_RS05225	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AM440_RS05230	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AM440_RS05235	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AM440_RS05250	COG0179	Fumarylacetoacetate (FAA) hydrolase
AM440_RS05285	COG2894	cell division
AM440_RS05345	COG2200	EAL domain
AM440_RS05370	COG2200	EAL domain
AM440_RS05375	COG0789	Transcriptional regulator
AM440_RS05380	COG5562	phage envelope protein
AM440_RS05390	COG0538	isocitrate dehydrogenase activity
AM440_RS05395	COG1187	pseudouridine synthase activity
AM440_RS05415	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AM440_RS05420	COG0745	RESPONSE REGULATOR receiver
AM440_RS05425	COG2205	protein histidine kinase activity
AM440_RS05430	COG2850	peptidyl-arginine hydroxylation
AM440_RS05455	COG1177	transmembrane transport
AM440_RS05460	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AM440_RS05470	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AM440_RS05475	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AM440_RS05485	COG4591	ABC-type transport system involved in lipoprotein release permease component
AM440_RS05490	COG1136	(ABC) transporter
AM440_RS05495	COG4591	ABC-type transport system involved in lipoprotein release permease component
AM440_RS05500	COG4763	Acyl-transferase
AM440_RS05505	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AM440_RS05510	COG1388	LysM domain
AM440_RS05510	COG1376	ErfK ybiS ycfS ynhG family protein
AM440_RS05520	COG1309	transcriptional regulator
AM440_RS05525	COG3134	Outer membrane lipoprotein
AM440_RS05535	COG1252	NADH dehydrogenase
AM440_RS05555	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
AM440_RS05560	COG5633	Lipoprotein
AM440_RS05565	COG0537	adenosine 5'-monophosphoramidase activity
AM440_RS05570	COG4773	Receptor
AM440_RS05575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM440_RS05575	COG1263	PTS System
AM440_RS05580	COG0084	hydrolase, TatD family'
AM440_RS05585	COG0470	DNA polymerase III
AM440_RS05595	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AM440_RS05600	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AM440_RS05605	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM440_RS05615	COG1028	Short-chain dehydrogenase reductase Sdr
AM440_RS05620	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AM440_RS05640	COG1399	metal-binding, possibly nucleic acid-binding protein
AM440_RS05645	COG0424	maF-like protein
AM440_RS05650	COG0564	pseudouridine synthase activity
AM440_RS05660	COG1530	ribonuclease E activity
AM440_RS05665	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AM440_RS05670	COG1256	bacterial-type flagellum assembly
AM440_RS05675	COG3951	Flagellar rod assembly protein muramidase FlgJ
AM440_RS05675	COG1705	Flagellar rod assembly protein muramidase FlgJ
AM440_RS05690	COG4786	Flagellar basal body rod
AM440_RS05695	COG4787	bacterial-type flagellum-dependent cell motility
AM440_RS05700	COG1749	Flagellar hook protein flgE
AM440_RS05705	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AM440_RS05710	COG1558	bacterial-type flagellum-dependent cell motility
AM440_RS05715	COG1815	bacterial-type flagellum-dependent cell motility
AM440_RS05720	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
AM440_RS05725	COG2747	anti-sigma28 factor FlgM
AM440_RS05730	COG3418	PFAM FlgN family protein
AM440_RS05735	COG0728	peptidoglycan biosynthetic process
AM440_RS05740	COG0673	inositol 2-dehydrogenase activity
AM440_RS05750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM440_RS05760	COG2999	glutathione oxidoreductase activity
AM440_RS05795	COG3038	cytochrome b561
AM440_RS05800	COG2353	YceI-like domain
AM440_RS05810	COG1560	Kdo2-lipid A biosynthetic process
AM440_RS05825	COG5645	(Lipo)protein
AM440_RS05830	COG2943	transferase activity, transferring hexosyl groups
AM440_RS05855	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM440_RS05860	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AM440_RS05895	COG2197	response regulator
AM440_RS05910	COG1462	curli production assembly transport component CsgG
AM440_RS05920	COG3381	protein complex oligomerization
AM440_RS05945	COG3706	GGDEF domain
AM440_RS05950	COG0457	Tetratricopeptide repeat
AM440_RS05955	COG1649	PFAM Uncharacterised BCR, COG1649
AM440_RS05955	COG0726	polysaccharide deacetylase
AM440_RS05960	COG1215	transferase activity, transferring glycosyl groups
AM440_RS05965	COG3658	cytochrome
AM440_RS05970	COG1702	phosphate starvation-inducible protein PhoH
AM440_RS05980	COG2822	iron ion transport
AM440_RS06000	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AM440_RS06015	COG0506	proline dehydrogenase activity
AM440_RS06015	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AM440_RS06015	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AM440_RS06020	COG1309	transcriptional regulator
AM440_RS06030	COG1335	isochorismatase
AM440_RS06055	COG2233	PERMEase
AM440_RS06065	COG3729	General stress protein
AM440_RS06110	COG0243	molybdopterin cofactor binding
AM440_RS06115	COG3005	denitrification pathway
AM440_RS06120	COG0745	RESPONSE REGULATOR receiver
AM440_RS06125	COG1879	ABC-type sugar transport system periplasmic component
AM440_RS06130	COG2205	protein histidine kinase activity
AM440_RS06130	COG2198	Histidine kinase
AM440_RS06130	COG0784	Response regulator, receiver
AM440_RS06135	COG0348	domain, Protein
AM440_RS06155	COG1278	Cold shock
AM440_RS06160	COG1278	Cold shock
AM440_RS06180	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM440_RS06185	COG1596	polysaccharide export
AM440_RS06190	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AM440_RS06195	COG3206	protein involved in exopolysaccharide biosynthesis
AM440_RS06195	COG0489	protein tyrosine kinase activity
AM440_RS06210	COG1294	oxidase, subunit
AM440_RS06215	COG1271	oxidase subunit
AM440_RS06220	COG1773	rubredoxin
AM440_RS06225	COG1999	signal sequence binding
AM440_RS06230	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AM440_RS06235	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
AM440_RS06240	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AM440_RS06245	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AM440_RS06255	COG0670	Belongs to the BI1 family
AM440_RS06260	COG2920	part of a sulfur-relay system
AM440_RS06265	COG1254	Belongs to the acylphosphatase family
AM440_RS06280	COG1832	CoA-binding protein
AM440_RS06295	COG0210	DNA helicase
AM440_RS06300	COG3304	Inner membrane component domain
AM440_RS06305	COG1289	transmembrane transporter activity
AM440_RS06310	COG3070	regulator of competence-specific genes
AM440_RS06325	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AM440_RS06325	COG2885	chlorophyll binding
AM440_RS06335	COG1067	ATP-dependent peptidase activity
AM440_RS06345	COG3130	regulation of translation
AM440_RS06350	COG3009	Protein conserved in bacteria
AM440_RS06355	COG3008	intermembrane lipid transfer
AM440_RS06355	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AM440_RS06360	COG2995	paraquat-inducible protein a
AM440_RS06365	COG0488	(ABC) transporter
AM440_RS06375	COG0633	Ferredoxin
AM440_RS06375	COG3217	Mosc domain protein beta barrel domain protein
AM440_RS06390	COG3121	Chaperone
AM440_RS06395	COG3539	Fimbrial protein
AM440_RS06400	COG3539	Fimbrial protein
AM440_RS06405	COG3539	Fimbrial protein
AM440_RS06410	COG3188	usher protein
AM440_RS06415	COG3121	Chaperone
AM440_RS06420	COG3539	Fimbrial protein
AM440_RS06430	COG0431	NADPH-dependent FMN reductase
AM440_RS06435	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM440_RS06445	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM440_RS06450	COG1116	anion transmembrane transporter activity
AM440_RS06455	COG0308	aminopeptidase N
AM440_RS06480	COG1448	Aminotransferase
AM440_RS06490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM440_RS06495	COG3108	Peptidase M15
AM440_RS06505	COG2989	Protein conserved in bacteria
AM440_RS06515	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
AM440_RS06525	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AM440_RS06530	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AM440_RS06535	COG3173	Aminoglycoside phosphotransferase
AM440_RS06550	COG3214	Protein conserved in bacteria
AM440_RS06560	COG1132	(ABC) transporter
AM440_RS06565	COG0658	competence protein
AM440_RS06565	COG2333	competence protein COMEC
AM440_RS06575	COG0539	negative regulation of cytoplasmic translation
AM440_RS06600	COG2323	membrane
AM440_RS06605	COG1944	ATP diphosphatase activity
AM440_RS06610	COG2116	formate transmembrane transporter activity
AM440_RS06615	COG1882	Formate acetyltransferase
AM440_RS06620	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM440_RS06625	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM440_RS06630	COG0583	DNA-binding transcription factor activity
AM440_RS06635	COG0531	amino acid
AM440_RS06645	COG1335	isochorismatase
AM440_RS06650	COG3302	dmso reductase anchor subunit
AM440_RS06655	COG0437	4 iron, 4 sulfur cluster binding
AM440_RS06660	COG0243	molybdopterin cofactor binding
AM440_RS06670	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AM440_RS06680	COG1178	ABC-type Fe3 transport system permease component
AM440_RS06680	COG1674	ftsk spoiiie
AM440_RS06685	COG1522	sequence-specific DNA binding
AM440_RS06695	COG0492	ferredoxin-NADP+ reductase activity
AM440_RS06700	COG4988	ABC transporter
AM440_RS06705	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AM440_RS06730	COG0542	response to heat
AM440_RS06740	COG1278	Cold shock
AM440_RS06745	COG1136	(ABC) transporter
AM440_RS06745	COG0577	efflux transmembrane transporter activity
AM440_RS06750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM440_RS06755	COG2990	Protein conserved in bacteria
AM440_RS06760	COG3593	DNA synthesis involved in DNA repair
AM440_RS06765	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AM440_RS06775	COG2431	L-lysine efflux transmembrane transporter activity
AM440_RS06785	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM440_RS06790	COG0028	Belongs to the TPP enzyme family
AM440_RS06795	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AM440_RS06800	COG0702	epimerase
AM440_RS06805	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM440_RS06810	COG3023	N-Acetylmuramoyl-L-alanine amidase
AM440_RS06825	COG1126	abc transporter atp-binding protein
AM440_RS06830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM440_RS06835	COG4215	(ABC) transporter
AM440_RS06840	COG4160	amino acid transport
AM440_RS06845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM440_RS06860	COG1177	transmembrane transport
AM440_RS06865	COG1176	ABC-type spermidine putrescine transport system, permease component I
AM440_RS06870	COG3842	ATPase activity
AM440_RS06875	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AM440_RS06895	COG0778	Nitroreductase
AM440_RS06905	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM440_RS06920	COG3226	Transcriptional regulator
AM440_RS06925	COG0738	Major facilitator superfamily
AM440_RS06930	COG0561	phosphatase activity
AM440_RS06940	COG2814	Major facilitator Superfamily
AM440_RS06945	COG0671	phosphoesterase, PA-phosphatase related
AM440_RS06950	COG1349	DNA-binding transcription factor activity
AM440_RS06955	COG1686	Belongs to the peptidase S11 family
AM440_RS06960	COG0625	glutathione transferase activity
AM440_RS06965	COG2133	pyrroloquinoline quinone binding
AM440_RS06980	COG2199	diguanylate cyclase activity
AM440_RS06985	COG2200	EAL domain
AM440_RS07000	COG0747	negative chemotaxis
AM440_RS07010	COG1446	asparaginase
AM440_RS07015	COG0303	'Molybdopterin
AM440_RS07020	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AM440_RS07025	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM440_RS07030	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM440_RS07035	COG1882	Formate acetyltransferase
AM440_RS07040	COG0561	phosphatase activity
AM440_RS07050	COG0488	(ABC) transporter
AM440_RS07055	COG1376	ErfK ybiS ycfS ynhG family protein
AM440_RS07060	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AM440_RS07065	COG1321	iron dependent repressor
AM440_RS07075	COG2194	sulfuric ester hydrolase activity
AM440_RS07080	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AM440_RS07085	COG5006	permease, DMT superfamily
AM440_RS07110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM440_RS07115	COG0765	amino acid transport
AM440_RS07120	COG1126	abc transporter atp-binding protein
AM440_RS07125	COG0668	transmembrane transport
AM440_RS07140	COG4774	siderophore transport
AM440_RS07150	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AM440_RS07160	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AM440_RS07165	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AM440_RS07170	COG1199	ATP-dependent helicase activity
AM440_RS07180	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
AM440_RS07185	COG0513	Belongs to the DEAD box helicase family
AM440_RS07190	COG1309	transcriptional regulator
AM440_RS07200	COG1131	(ABC) transporter
AM440_RS07205	COG0842	Transport permease protein
AM440_RS07210	COG0842	Transport permease protein
AM440_RS07220	COG3568	Endonuclease Exonuclease Phosphatase
AM440_RS07225	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM440_RS07230	COG0392	lysyltransferase activity
AM440_RS07235	COG0670	Belongs to the BI1 family
AM440_RS07240	COG0670	Belongs to the BI1 family
AM440_RS07245	COG0314	molybdopterin synthase activity
AM440_RS07250	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AM440_RS07260	COG0521	Mo-molybdopterin cofactor biosynthetic process
AM440_RS07270	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AM440_RS07280	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AM440_RS07285	COG2226	methyltransferase
AM440_RS07300	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AM440_RS07305	COG1881	PFAM PEBP family protein
AM440_RS07315	COG4677	pectinesterase activity
AM440_RS07320	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AM440_RS07325	COG0471	metal ion transport
AM440_RS07330	COG2828	Protein conserved in bacteria
AM440_RS07335	COG0583	DNA-binding transcription factor activity
AM440_RS07345	COG0561	phosphatase activity
AM440_RS07350	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AM440_RS07355	COG4149	molybdate abc transporter
AM440_RS07360	COG0725	ABC transporter, periplasmic molybdate-binding protein
AM440_RS07375	COG3585	molybdate ion transport
AM440_RS07375	COG2005	Transcriptional regulator
AM440_RS07380	COG1119	ATPase activity
AM440_RS07385	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AM440_RS07390	COG1085	galactose-1-phosphate uridylyltransferase
AM440_RS07400	COG2017	converts alpha-aldose to the beta-anomer
AM440_RS07410	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM440_RS07425	COG1230	cation diffusion facilitator family transporter
AM440_RS07430	COG3201	nicotinamide mononucleotide transporter
AM440_RS07475	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AM440_RS07480	COG2885	chlorophyll binding
AM440_RS07490	COG3064	Membrane
AM440_RS07495	COG0848	biopolymer transport protein
AM440_RS07500	COG0811	peptide transport
AM440_RS07505	COG0824	Thioesterase
AM440_RS07510	COG3790	cyd operon protein YbgE
AM440_RS07515	COG4890	Cyd operon protein YbgT
AM440_RS07520	COG1294	oxidase, subunit
AM440_RS07525	COG1271	oxidase subunit
AM440_RS07535	COG0383	alpha-mannosidase activity
AM440_RS07540	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM440_RS07540	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM440_RS07540	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM440_RS07545	COG2188	Transcriptional regulator
AM440_RS07550	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AM440_RS07560	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM440_RS07565	COG0567	Dehydrogenase, E1 component
AM440_RS07570	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AM440_RS07575	COG1053	succinate dehydrogenase
AM440_RS07580	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AM440_RS07585	COG2009	succinate dehydrogenase
AM440_RS07600	COG0372	Belongs to the citrate synthase family
AM440_RS07605	COG3539	Fimbrial protein
AM440_RS07610	COG3188	usher protein
AM440_RS07615	COG3121	Chaperone
AM440_RS07620	COG3539	Fimbrial protein
AM440_RS07625	COG3180	Ammonia monooxygenase
AM440_RS07640	COG1984	allophanate hydrolase subunit 2
AM440_RS07645	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AM440_RS07650	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AM440_RS07660	COG0415	Belongs to the DNA photolyase family
AM440_RS07675	COG5433	transposase activity
AM440_RS07685	COG3209	COG3209 Rhs family protein
AM440_RS07695	COG3209	COG3209 Rhs family protein
AM440_RS07700	COG3209	COG3209 Rhs family protein
AM440_RS07730	COG2205	protein histidine kinase activity
AM440_RS07735	COG0745	RESPONSE REGULATOR receiver
AM440_RS07745	COG1982	Orn Lys Arg decarboxylase major
AM440_RS07750	COG0531	amino acid
AM440_RS07770	COG0033	Phosphoglucomutase
AM440_RS07775	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AM440_RS07780	COG0596	Alpha beta hydrolase
AM440_RS07790	COG0716	FMN binding
AM440_RS07800	COG0735	belongs to the Fur family
AM440_RS07820	COG2190	(PTS) system
AM440_RS07820	COG1263	PTS System
AM440_RS07820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM440_RS07830	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AM440_RS07835	COG1940	carbohydrate kinase activity
AM440_RS07835	COG1846	Transcriptional regulator
AM440_RS07840	COG0647	UMP catabolic process
AM440_RS07850	COG0367	asparagine synthase
AM440_RS07895	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM440_RS07905	COG1702	phosphate starvation-inducible protein PhoH
AM440_RS07915	COG4535	Mg2 and Co2 transporter CorC
AM440_RS07920	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AM440_RS07935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM440_RS07940	COG0765	amino acid transport
AM440_RS07945	COG0765	amino acid transport
AM440_RS07950	COG1126	abc transporter atp-binding protein
AM440_RS07960	COG0443	Heat shock 70 kDa protein
AM440_RS07965	COG2214	Heat shock protein DnaJ domain protein
AM440_RS07975	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AM440_RS07980	COG2214	Heat shock protein DnaJ domain protein
AM440_RS07990	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AM440_RS07995	COG2888	peptidyl-tyrosine sulfation
AM440_RS08010	COG1466	dna polymerase III delta subunit
AM440_RS08020	COG0406	alpha-ribazole phosphatase activity
AM440_RS08025	COG0799	negative regulation of ribosome biogenesis
AM440_RS08035	COG0768	penicillin binding
AM440_RS08040	COG0772	Belongs to the SEDS family
AM440_RS08045	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AM440_RS08050	COG1686	Belongs to the peptidase S11 family
AM440_RS08070	COG0583	DNA-binding transcription factor activity
AM440_RS08085	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AM440_RS08090	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM440_RS08115	COG3069	C4-dicarboxylate transmembrane transporter activity
AM440_RS08120	COG4565	transcriptional regulatory protein
AM440_RS08125	COG3290	protein histidine kinase activity
AM440_RS08130	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
AM440_RS08140	COG2301	Belongs to the HpcH HpaI aldolase family
AM440_RS08145	COG3051	citrate lyase alpha subunit
AM440_RS08160	COG0471	metal ion transport
AM440_RS08165	COG3719	Belongs to the RNase T2 family
AM440_RS08175	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AM440_RS08185	COG1063	alcohol dehydrogenase
AM440_RS08190	COG0589	response to stress
AM440_RS08195	COG3634	alkyl hydroperoxide reductase activity
AM440_RS08200	COG0450	alkyl hydroperoxide reductase
AM440_RS08205	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM440_RS08215	COG0583	DNA-binding transcription factor activity
AM440_RS08220	COG3969	phosphoadenosine phosphosulfate
AM440_RS08225	COG1475	DNA binding
AM440_RS08230	COG0436	Aminotransferase
AM440_RS08235	COG0371	Dehydrogenase
AM440_RS08240	COG2879	small protein
AM440_RS08245	COG1966	Carbon starvation protein
AM440_RS08250	COG2050	protein possibly involved in aromatic compounds catabolism
AM440_RS08255	COG1028	Short-chain dehydrogenase reductase Sdr
AM440_RS08260	COG3433	isochorismatase activity
AM440_RS08260	COG1535	isochorismatase
AM440_RS08265	COG1021	2,3-dihydroxybenzoate-AMP ligase
AM440_RS08270	COG1169	isochorismate synthase
AM440_RS08280	COG4592	Periplasmic binding protein
AM440_RS08290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM440_RS08295	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM440_RS08300	COG1120	ATPase activity
AM440_RS08305	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
AM440_RS08310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM440_RS08310	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AM440_RS08315	COG3251	PFAM MbtH domain protein
AM440_RS08320	COG2382	esterase
AM440_RS08325	COG4771	TonB-dependent receptor
AM440_RS08330	COG2977	Belongs to the P-Pant transferase superfamily
AM440_RS08370	COG2315	Protein conserved in bacteria
AM440_RS08375	COG0778	Nitroreductase
AM440_RS08380	COG0668	transmembrane transport
AM440_RS08385	COG1113	amino acid transport
AM440_RS08390	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM440_RS08395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM440_RS08400	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM440_RS08405	COG1538	Outer membrane efflux protein
AM440_RS08415	COG0745	RESPONSE REGULATOR receiver
AM440_RS08420	COG5002	protein histidine kinase activity
AM440_RS08450	COG4104	PAAR repeat-containing protein
AM440_RS08450	COG3209	COG3209 Rhs family protein
AM440_RS08455	COG5433	transposase activity
AM440_RS08460	COG1215	transferase activity, transferring glycosyl groups
AM440_RS08465	COG4783	chaperone-mediated protein folding
AM440_RS08480	COG2207	Transcriptional regulator
AM440_RS08495	COG2197	response regulator
AM440_RS08500	COG3539	Fimbrial protein
AM440_RS08505	COG3539	Fimbrial protein
AM440_RS08510	COG3188	usher protein
AM440_RS08515	COG3121	Chaperone
AM440_RS08520	COG3539	Fimbrial protein
AM440_RS08530	COG2501	S4 domain
AM440_RS08535	COG1988	membrane-bound metal-dependent
AM440_RS08545	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AM440_RS08560	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AM440_RS08565	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AM440_RS08570	COG0549	Belongs to the carbamate kinase family
AM440_RS08580	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AM440_RS08585	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AM440_RS08590	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AM440_RS08595	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AM440_RS08600	COG3257	ureidoglycine aminohydrolase activity
AM440_RS08605	COG1929	Belongs to the glycerate kinase type-1 family
AM440_RS08610	COG2233	PERMEase
AM440_RS08620	COG1953	Uracil, thiamine, allantoin
AM440_RS08625	COG2084	Dehydrogenase
AM440_RS08630	COG3622	Belongs to the hyi family
AM440_RS08635	COG3960	tartronate-semialdehyde synthase activity
AM440_RS08640	COG1414	Transcriptional regulator
AM440_RS08650	COG0583	DNA-binding transcription factor activity
AM440_RS08660	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AM440_RS08665	COG4181	ATPase activity
AM440_RS08670	COG2755	lipolytic protein G-D-S-L family
AM440_RS08675	COG0300	oxidoreductase activity
AM440_RS08680	COG3118	belongs to the thioredoxin family
AM440_RS08685	COG0390	transport system, permease component
AM440_RS08690	COG4619	ABC transporter
AM440_RS08695	COG0330	HflC and HflK could
AM440_RS08700	COG1585	Membrane protein implicated in regulation of membrane protease activity
AM440_RS08705	COG0789	Transcriptional regulator
AM440_RS08715	COG0531	amino acid
AM440_RS08725	COG2217	Heavy metal translocating P-type atpase
AM440_RS08730	COG3093	addiction module antidote protein HigA
AM440_RS08735	COG3735	TraB family
AM440_RS08745	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AM440_RS08750	COG0737	Belongs to the 5'-nucleotidase family
AM440_RS08760	COG2223	nitrite transmembrane transporter activity
AM440_RS08765	COG4651	solute:proton antiporter activity
AM440_RS08765	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM440_RS08770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM440_RS08810	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AM440_RS08825	COG2832	Protein of unknown function (DUF454)
AM440_RS08830	COG3923	Primosomal replication protein n
AM440_RS08840	COG1196	nuclear chromosome segregation
AM440_RS08840	COG3264	Mechanosensitive ion channel
AM440_RS08850	COG1309	transcriptional regulator
AM440_RS08855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM440_RS08860	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM440_RS08875	COG0110	maltose O-acetyltransferase activity
AM440_RS08885	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AM440_RS08890	COG5507	3-demethylubiquinone-9 3-methyltransferase
AM440_RS08900	COG3695	enzyme binding
AM440_RS08905	COG3126	Type III secretion system lipoprotein chaperone (YscW)
AM440_RS08910	COG1946	Acyl-CoA thioesterase
AM440_RS08915	COG0004	ammonium transporteR
AM440_RS08920	COG0347	Belongs to the P(II) protein family
AM440_RS08925	COG1132	(ABC) transporter
AM440_RS08930	COG1132	(ABC) transporter
AM440_RS08935	COG1522	sequence-specific DNA binding
AM440_RS08945	COG4533	DNA binding
AM440_RS08955	COG0824	Thioesterase
AM440_RS08960	COG1555	photosystem II stabilization
AM440_RS08965	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM440_RS08970	COG0776	regulation of translation
AM440_RS08975	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AM440_RS09000	COG0271	Belongs to the BolA IbaG family
AM440_RS09010	COG3056	Lipoprotein
AM440_RS09015	COG2223	nitrite transmembrane transporter activity
AM440_RS09020	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AM440_RS09025	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AM440_RS09030	COG1845	cytochrome c oxidase, subunit III
AM440_RS09035	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AM440_RS09045	COG2814	Major facilitator Superfamily
AM440_RS09055	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AM440_RS09060	COG0693	protein deglycase activity
AM440_RS09075	COG0142	geranyltranstransferase activity
AM440_RS09085	COG0667	Aldo Keto reductase
AM440_RS09090	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AM440_RS09095	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AM440_RS09110	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM440_RS09110	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM440_RS09120	COG4238	major outer membrane lipoprotein
AM440_RS09125	COG3248	Nucleoside-binding outer membrane protein
AM440_RS09130	COG1403	HNH endonuclease
AM440_RS09135	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AM440_RS09140	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AM440_RS09145	COG1862	Preprotein translocase
AM440_RS09165	COG0366	Alpha amylase catalytic
AM440_RS09170	COG1113	amino acid transport
AM440_RS09175	COG1114	Component of the transport system for branched-chain amino acids
AM440_RS09180	COG5002	protein histidine kinase activity
AM440_RS09185	COG0745	RESPONSE REGULATOR receiver
AM440_RS09190	COG0420	3'-5' exonuclease activity
AM440_RS09195	COG0419	ATPase involved in DNA repair
AM440_RS09200	COG2814	Major facilitator Superfamily
AM440_RS09205	COG1940	carbohydrate kinase activity
AM440_RS09230	COG4126	flavin adenine dinucleotide binding
AM440_RS09255	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AM440_RS09260	COG3706	GGDEF domain
AM440_RS09270	COG1785	Belongs to the alkaline phosphatase family
AM440_RS09285	COG1181	Belongs to the D-alanine--D-alanine ligase family
AM440_RS09305	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AM440_RS09315	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AM440_RS09320	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM440_RS09325	COG3468	outer membrane autotransporter barrel domain protein
AM440_RS09335	COG0113	porphobilinogen synthase activity
AM440_RS09340	COG2175	clavaminate synthase activity
AM440_RS09345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM440_RS09355	COG4521	taurine ABC transporter
AM440_RS09365	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AM440_RS09375	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AM440_RS09380	COG1215	transferase activity, transferring glycosyl groups
AM440_RS09410	COG3122	Protein conserved in bacteria
AM440_RS09415	COG2814	Major facilitator Superfamily
AM440_RS09430	COG3971	2-oxopent-4-enoate hydratase activity
AM440_RS09450	COG1414	Transcriptional regulator
AM440_RS09455	COG1609	Transcriptional regulator
AM440_RS09465	COG3250	beta-galactosidase activity
AM440_RS09470	COG2223	nitrite transmembrane transporter activity
AM440_RS09475	COG0110	maltose O-acetyltransferase activity
AM440_RS09480	COG2807	transmembrane transport
AM440_RS09490	COG0288	reversible hydration of carbon dioxide
AM440_RS09495	COG0583	DNA-binding transcription factor activity
AM440_RS09500	COG0402	S-adenosylhomocysteine deaminase activity
AM440_RS09505	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AM440_RS09510	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AM440_RS09515	COG2079	MmgE PrpD family protein
AM440_RS09520	COG0372	Belongs to the citrate synthase family
AM440_RS09525	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AM440_RS09530	COG3829	transcription factor binding
AM440_RS09540	COG1280	lysine exporter protein (LysE YggA)
AM440_RS09555	COG1064	alcohol dehydrogenase
AM440_RS09560	COG0402	S-adenosylhomocysteine deaminase activity
AM440_RS09565	COG0549	Belongs to the carbamate kinase family
AM440_RS09575	COG1304	FMN binding
AM440_RS09580	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AM440_RS09590	COG0666	response to abiotic stimulus
AM440_RS09605	COG0583	DNA-binding transcription factor activity
AM440_RS09610	COG2771	luxR family
AM440_RS09610	COG2200	EAL domain
AM440_RS09625	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM440_RS09665	COG1556	Lactate utilization protein
AM440_RS09670	COG1139	Iron-sulfur cluster binding protein
AM440_RS09675	COG0247	lactate metabolic process
AM440_RS09680	COG2207	Transcriptional regulator
AM440_RS09685	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM440_RS09695	COG3059	membrane
AM440_RS09700	COG3708	Transcriptional regulator
AM440_RS09700	COG2207	Transcriptional regulator
AM440_RS09760	COG3188	usher protein
AM440_RS09770	COG3121	Chaperone
AM440_RS09775	COG0727	PFAM Uncharacterised protein family (UPF0153)
AM440_RS09785	COG3477	response to acidic pH
AM440_RS09795	COG2080	2 iron, 2 sulfur cluster binding
AM440_RS09800	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AM440_RS09805	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AM440_RS09810	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AM440_RS09815	COG0583	DNA-binding transcription factor activity
AM440_RS09825	COG2246	polysaccharide biosynthetic process
AM440_RS09860	COG3778	Protein conserved in bacteria
AM440_RS09865	COG3299	homolog of phage Mu protein gp47
AM440_RS09885	COG4228	DNA circulation
AM440_RS09905	COG4386	tail sheath protein
AM440_RS09950	COG4695	Portal protein
AM440_RS09960	COG4626	Terminase
AM440_RS09960	COG1802	Transcriptional regulator
AM440_RS10140	COG0582	viral genome integration into host DNA
AM440_RS10160	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AM440_RS10180	COG2195	Cleaves the N-terminal amino acid of tripeptides
AM440_RS10185	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AM440_RS10190	COG1690	Belongs to the RtcB family
AM440_RS10195	COG0454	-acetyltransferase
AM440_RS10205	COG2161	toxin-antitoxin pair type II binding
AM440_RS10225	COG1943	Transposase
AM440_RS10230	COG0791	NLP P60 protein
AM440_RS10235	COG3034	peptidoglycan biosynthetic process
AM440_RS10240	COG0121	glutamine amidotransferase
AM440_RS10250	COG1960	acyl-CoA dehydrogenase activity
AM440_RS10260	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM440_RS10265	COG5433	transposase activity
AM440_RS10275	COG3209	COG3209 Rhs family protein
AM440_RS10330	COG3157	Type VI secretion system effector, Hcp
AM440_RS10335	COG4104	PAAR repeat-containing protein
AM440_RS10355	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM440_RS10365	COG2226	methyltransferase
AM440_RS10375	COG0741	lytic transglycosylase activity
AM440_RS10375	COG1388	LysM domain
AM440_RS10380	COG2226	methyltransferase
AM440_RS10390	COG0583	DNA-binding transcription factor activity
AM440_RS10395	COG0656	L-ascorbic acid biosynthetic process
AM440_RS10430	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AM440_RS10435	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AM440_RS10440	COG2011	ABC-type metal ion transport system permease component
AM440_RS10445	COG1464	Belongs to the NlpA lipoprotein family
AM440_RS10455	COG1720	tRNA m6t6A37 methyltransferase activity
AM440_RS10465	COG0791	NLP P60 protein
AM440_RS10470	COG3015	lipoprotein NlpE involved in copper resistance
AM440_RS10475	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AM440_RS10480	COG4681	YaeQ
AM440_RS10490	COG4568	rho-dependent transcription termination
AM440_RS10500	COG0346	lactoylglutathione lyase activity
AM440_RS10505	COG1982	Orn Lys Arg decarboxylase major
AM440_RS10515	COG0587	DNA-directed DNA polymerase activity
AM440_RS10540	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM440_RS10545	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AM440_RS10555	COG0750	zinc metalloprotease
AM440_RS10560	COG0575	Belongs to the CDS family
AM440_RS10565	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AM440_RS10570	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AM440_RS10605	COG0024	Methionine aminopeptidase
AM440_RS10620	COG1408	metallophosphoesterase
AM440_RS10630	COG3835	regulator
AM440_RS10635	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM440_RS10655	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AM440_RS10660	COG2860	membrane
AM440_RS10680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM440_RS10685	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AM440_RS10690	COG1120	ATPase activity
AM440_RS10695	COG4774	siderophore transport
AM440_RS10700	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AM440_RS10705	COG1643	Atp-dependent helicase
AM440_RS10710	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AM440_RS10720	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AM440_RS10730	COG0617	tRNA 3'-terminal CCA addition
AM440_RS10735	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AM440_RS10745	COG3121	Chaperone
AM440_RS10750	COG3188	usher protein
AM440_RS10755	COG3539	Fimbrial protein
AM440_RS10760	COG3539	Fimbrial protein
AM440_RS10785	COG5464	transposase or invertase
AM440_RS10805	COG0726	polysaccharide deacetylase
AM440_RS10810	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM440_RS10815	COG0842	Transport permease protein
AM440_RS10820	COG1131	(ABC) transporter
AM440_RS10825	COG0288	reversible hydration of carbon dioxide
AM440_RS10830	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AM440_RS10835	COG4993	Dehydrogenase
AM440_RS10840	COG2132	Multicopper oxidase
AM440_RS10865	COG1049	propionate catabolic process, 2-methylcitrate cycle
AM440_RS10875	COG3064	Membrane
AM440_RS10880	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM440_RS10885	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM440_RS10890	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AM440_RS10900	COG2186	Transcriptional regulator
AM440_RS10910	COG3725	Membrane protein required for beta-lactamase induction
AM440_RS10915	COG3023	N-Acetylmuramoyl-L-alanine amidase
AM440_RS10920	COG0157	Belongs to the NadC ModD family
AM440_RS10930	COG4969	Belongs to the N-Me-Phe pilin family
AM440_RS10935	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AM440_RS10940	COG1459	type II secretion system
AM440_RS10950	COG0237	dephospho-CoA kinase activity
AM440_RS10965	COG0494	nUDIX hydrolase
AM440_RS10985	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AM440_RS10990	COG0849	cell division
AM440_RS10995	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AM440_RS11000	COG1181	Belongs to the D-alanine--D-alanine ligase family
AM440_RS11015	COG0772	Belongs to the SEDS family
AM440_RS11020	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AM440_RS11030	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AM440_RS11035	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AM440_RS11040	COG0768	penicillin binding
AM440_RS11045	COG3116	cell division
AM440_RS11055	COG2001	Belongs to the MraZ family
AM440_RS11065	COG1609	Transcriptional regulator
AM440_RS11075	COG0440	acetolactate synthase activity
AM440_RS11080	COG0028	Belongs to the TPP enzyme family
AM440_RS11085	COG0583	DNA-binding transcription factor activity
AM440_RS11100	COG0473	3-isopropylmalate dehydrogenase activity
AM440_RS11115	COG2814	Major facilitator Superfamily
AM440_RS11130	COG4143	(ABC) transporter
AM440_RS11135	COG1178	ABC-type Fe3 transport system permease component
AM440_RS11145	COG0586	Pfam SNARE associated Golgi protein
AM440_RS11150	COG4977	sequence-specific DNA binding
AM440_RS11170	COG0235	Class ii aldolase
AM440_RS11175	COG0417	DNA replication proofreading
AM440_RS11185	COG0564	pseudouridine synthase activity
AM440_RS11190	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AM440_RS11195	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AM440_RS11200	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM440_RS11225	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AM440_RS11240	COG2271	Major facilitator Superfamily
AM440_RS11245	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AM440_RS11250	COG0644	oxidoreductase
AM440_RS11305	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AM440_RS11310	COG0505	Belongs to the CarA family
AM440_RS11330	COG1047	Peptidyl-prolyl cis-trans
AM440_RS11345	COG0196	riboflavin kinase activity
AM440_RS11375	COG0583	DNA-binding transcription factor activity
AM440_RS11410	COG4735	regulation of single-species biofilm formation
AM440_RS11415	COG1584	GPR1 FUN34 yaaH family protein
AM440_RS11420	COG0521	Mo-molybdopterin cofactor biosynthetic process
AM440_RS11425	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM440_RS11430	COG1115	amino acid carrier protein
AM440_RS11445	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AM440_RS11455	COG0527	aspartate kinase activity
AM440_RS11455	COG0460	homoserine dehydrogenase
AM440_RS11465	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AM440_RS11475	COG0745	RESPONSE REGULATOR receiver
AM440_RS11480	COG4452	Inner membrane protein CreD
AM440_RS11485	COG2205	protein histidine kinase activity
AM440_RS11490	COG0745	RESPONSE REGULATOR receiver
AM440_RS11495	COG3045	CreA protein
AM440_RS11500	COG2207	Transcriptional regulator
AM440_RS11500	COG3708	Transcriptional regulator
AM440_RS11520	COG0741	lytic transglycosylase activity
AM440_RS11530	COG0488	(ABC) transporter
AM440_RS11535	COG1056	cytidyltransferase-related domain
AM440_RS11535	COG3172	ATPase kinase involved in NAD metabolism
AM440_RS11540	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AM440_RS11545	COG0560	Phosphoserine phosphatase
AM440_RS11550	COG3726	membrane protein affecting hemolysin expression
AM440_RS11580	COG1328	CTP reductase activity
AM440_RS11585	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM440_RS11590	COG0084	hydrolase, TatD family'
AM440_RS11595	COG4667	esterase of the alpha-beta hydrolase superfamily
AM440_RS11605	COG2823	Periplasmic or secreted lipoprotein
AM440_RS11615	COG1011	Hydrolase
AM440_RS11620	COG0456	acetyltransferase
AM440_RS11625	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
AM440_RS11655	COG4114	ferric iron reductase
AM440_RS11660	COG2197	response regulator
AM440_RS11665	COG2197	response regulator
AM440_RS11670	COG2966	Psort location CytoplasmicMembrane, score
AM440_RS11685	COG1484	DNA-dependent DNA replication
AM440_RS11700	COG1063	alcohol dehydrogenase
AM440_RS11705	COG1802	Transcriptional regulator
AM440_RS11710	COG2271	Major facilitator Superfamily
AM440_RS11715	COG0840	transmembrane signaling receptor activity
AM440_RS11725	COG1966	Carbon starvation protein
AM440_RS11730	COG2879	small protein
AM440_RS11735	COG0523	cobalamin synthesis protein
AM440_RS11755	COG2814	Major facilitator Superfamily
AM440_RS11760	COG2733	membrane
AM440_RS11765	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
AM440_RS11770	COG1924	4 iron, 4 sulfur cluster binding
AM440_RS11785	COG0477	Major facilitator Superfamily
AM440_RS11800	COG3366	ferrous iron transmembrane transporter activity
AM440_RS11805	COG0700	Nucleoside recognition
AM440_RS11810	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AM440_RS11815	COG0583	DNA-binding transcription factor activity
AM440_RS11835	COG2186	Transcriptional regulator
AM440_RS11840	COG0246	Mannitol dehydrogenase
AM440_RS11855	COG2610	gluconate transmembrane transporter activity
AM440_RS11860	COG3539	Fimbrial protein
AM440_RS11865	COG3539	Fimbrial protein
AM440_RS11870	COG3539	Fimbrial protein
AM440_RS11875	COG3188	usher protein
AM440_RS11880	COG3121	Chaperone
AM440_RS11885	COG3539	Fimbrial protein
AM440_RS11905	COG4974	Belongs to the 'phage' integrase family
AM440_RS11910	COG0582	viral genome integration into host DNA
AM440_RS11925	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AM440_RS11930	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
AM440_RS11950	COG1401	restriction endodeoxyribonuclease activity
AM440_RS11975	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM440_RS12000	COG0604	alcohol dehydrogenase
AM440_RS12020	COG0440	acetolactate synthase activity
AM440_RS12025	COG1349	DNA-binding transcription factor activity
AM440_RS12035	COG0738	Major facilitator superfamily
AM440_RS12050	COG3037	sugar-specific permease SgaT UlaA
AM440_RS12060	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM440_RS12075	COG4372	Transposase
AM440_RS12080	COG3547	Transposase (IS116 IS110 IS902 family)
AM440_RS12090	COG3436	PFAM IS66 Orf2 family protein
AM440_RS12155	COG1064	alcohol dehydrogenase
AM440_RS12160	COG0433	COG0433 Predicted ATPase
AM440_RS12165	COG0795	lipopolysaccharide-transporting ATPase activity
AM440_RS12170	COG0795	lipopolysaccharide-transporting ATPase activity
AM440_RS12180	COG2927	DNA polymerase III (CHI subunit)
AM440_RS12185	COG0525	valine-tRNA ligase activity
AM440_RS12190	COG4269	membrane
AM440_RS12195	COG0456	acetyltransferase
AM440_RS12200	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
AM440_RS12225	COG2731	YhcH YjgK YiaL family protein
AM440_RS12230	COG1309	transcriptional regulator
AM440_RS12235	COG1028	Short-chain dehydrogenase reductase Sdr
AM440_RS12240	COG0251	oxidation-reduction process
AM440_RS12265	COG0251	oxidation-reduction process
AM440_RS12270	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AM440_RS12275	COG1609	Transcriptional regulator
AM440_RS12280	COG1263	PTS System
AM440_RS12280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM440_RS12285	COG0366	Alpha amylase catalytic
AM440_RS12290	COG1328	CTP reductase activity
AM440_RS12295	COG0602	queuosine metabolic process
AM440_RS12300	COG3783	Cytochrome b(562)
AM440_RS12305	COG0312	modulator of DNA gyrase
AM440_RS12315	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AM440_RS12325	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM440_RS12330	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM440_RS12335	COG1129	ABC transporter
AM440_RS12340	COG1879	ABC-type sugar transport system periplasmic component
AM440_RS12345	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AM440_RS12350	COG2337	Toxic component of a toxin-antitoxin (TA) module
AM440_RS12355	COG2336	PFAM SpoVT AbrB
AM440_RS12360	COG2105	PFAM AIG2 family protein
AM440_RS12365	COG2911	Protein conserved in bacteria
AM440_RS12370	COG0729	surface antigen
AM440_RS12385	COG1253	flavin adenine dinucleotide binding
AM440_RS12395	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AM440_RS12400	COG1218	3'(2'),5'-bisphosphate nucleotidase
AM440_RS12405	COG0737	Belongs to the 5'-nucleotidase family
AM440_RS12410	COG1733	regulation of RNA biosynthetic process
AM440_RS12415	COG0702	epimerase
AM440_RS12420	COG0697	spore germination
AM440_RS12430	COG1113	amino acid transport
AM440_RS12435	COG0545	Peptidyl-prolyl cis-trans isomerase
AM440_RS12445	COG3061	Opacity-associated protein A
AM440_RS12450	COG1309	transcriptional regulator
AM440_RS12465	COG1024	Enoyl-CoA hydratase
AM440_RS12470	COG4670	ketone body catabolic process
AM440_RS12475	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AM440_RS12480	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AM440_RS12490	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AM440_RS12500	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AM440_RS12540	COG3414	Phosphotransferase system galactitol-specific IIB component
AM440_RS12560	COG1073	alpha beta
AM440_RS12565	COG3650	response to hydrogen peroxide
AM440_RS12580	COG1960	acyl-CoA dehydrogenase activity
AM440_RS12585	COG0754	glutathionylspermidine amidase activity
AM440_RS12590	COG5463	Belongs to the UPF0441 family
AM440_RS12595	COG3766	membrane
AM440_RS12605	COG1842	Phage shock protein A
AM440_RS12610	COG3789	protein conserved in bacteria
AM440_RS12615	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM440_RS12620	COG0557	exoribonuclease II activity
AM440_RS12635	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AM440_RS12640	COG0330	HflC and HflK could
AM440_RS12645	COG0330	HflC and HflK could
AM440_RS12650	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AM440_RS12670	COG0860	N-Acetylmuramoyl-L-alanine amidase
AM440_RS12675	COG0802	atpase or kinase
AM440_RS12680	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AM440_RS12680	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AM440_RS12685	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AM440_RS12720	COG3264	Mechanosensitive ion channel
AM440_RS12720	COG1511	domain protein
AM440_RS12735	COG0531	amino acid
AM440_RS12745	COG1053	succinate dehydrogenase
AM440_RS12750	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AM440_RS12765	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AM440_RS12770	COG3040	lipid binding
AM440_RS12775	COG2076	Multidrug Resistance protein
AM440_RS12780	COG5510	response to toxic substance
AM440_RS12785	COG5510	response to toxic substance
AM440_RS12795	COG1509	lysine 2,3-aminomutase activity
AM440_RS12820	COG0531	amino acid
AM440_RS12825	COG3030	protein affecting phage T7 exclusion by the F plasmid
AM440_RS12830	COG1027	Aspartate ammonia-lyase
AM440_RS12835	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AM440_RS12845	COG4232	protein-disulfide reductase activity
AM440_RS12850	COG1309	transcriptional regulator
AM440_RS12865	COG3710	Transcriptional regulator
AM440_RS12870	COG0531	amino acid
AM440_RS12875	COG1982	Orn Lys Arg decarboxylase major
AM440_RS12880	COG3104	oligopeptide transport
AM440_RS12885	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AM440_RS12905	COG2388	GCN5-related N-acetyl-transferase
AM440_RS12910	COG3592	Divergent 4Fe-4S mono-cluster
AM440_RS12915	COG3290	protein histidine kinase activity
AM440_RS12920	COG4565	transcriptional regulatory protein
AM440_RS12930	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AM440_RS12935	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AM440_RS12935	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AM440_RS12940	COG3647	Membrane
AM440_RS12945	COG2211	Major facilitator Superfamily
AM440_RS12950	COG1486	melibiose metabolic process
AM440_RS12955	COG2169	Transcriptional regulator
AM440_RS12960	COG1982	Orn Lys Arg decarboxylase major
AM440_RS12965	COG2207	Transcriptional regulator
AM440_RS12970	COG0531	amino acid
AM440_RS12975	COG2194	sulfuric ester hydrolase activity
AM440_RS12980	COG0745	RESPONSE REGULATOR receiver
AM440_RS12985	COG0642	Histidine kinase
AM440_RS12995	COG0477	Major facilitator Superfamily
AM440_RS13015	COG2824	Alkylphosphonate utilization operon protein PhnA
AM440_RS13020	COG2764	glyoxalase bleomycin resistance protein dioxygenase
AM440_RS13030	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AM440_RS13035	COG3639	organic phosphonate transmembrane transporter activity
AM440_RS13040	COG2188	Transcriptional regulator
AM440_RS13045	COG3624	Phosphonate C-P lyase system protein PhnG
AM440_RS13050	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AM440_RS13055	COG3626	phosphonate metabolism
AM440_RS13060	COG3627	carbon phosphorus lyase activity
AM440_RS13065	COG4107	phosphonate C-P lyase system protein PhnK
AM440_RS13070	COG4778	phosphonate C-P lyase system protein PhnL
AM440_RS13075	COG3454	Phosphonate metabolism
AM440_RS13080	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AM440_RS13085	COG0456	acetyltransferase
AM440_RS13090	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AM440_RS13100	COG0698	ribose 5-phosphate isomerase
AM440_RS13110	COG1737	Transcriptional regulator
AM440_RS13115	COG1879	ABC-type sugar transport system periplasmic component
AM440_RS13120	COG1129	ABC transporter
AM440_RS13125	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM440_RS13130	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AM440_RS13135	COG1940	carbohydrate kinase activity
AM440_RS13140	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AM440_RS13150	COG1566	PFAM secretion protein HlyD family protein
AM440_RS13155	COG1289	transmembrane transporter activity
AM440_RS13160	COG1538	Outer membrane efflux protein
AM440_RS13170	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AM440_RS13175	COG1301	dicarboxylic acid transport
AM440_RS13185	COG4235	cytochrome complex assembly
AM440_RS13190	COG3088	subunit of a heme lyase
AM440_RS13195	COG1138	Cytochrome C-type biogenesis protein
AM440_RS13200	COG3301	Polysulphide reductase, NrfD
AM440_RS13205	COG0437	4 iron, 4 sulfur cluster binding
AM440_RS13210	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
AM440_RS13225	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AM440_RS13230	COG3162	membrane
AM440_RS13240	COG1357	PFAM Pentapeptide repeats (8 copies)
AM440_RS13245	COG0025	NhaP-type Na H and K H
AM440_RS13250	COG2252	PERMEase
AM440_RS13270	COG0789	Transcriptional regulator
AM440_RS13275	COG2207	Transcriptional regulator
AM440_RS13280	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AM440_RS13295	COG0629	single-stranded DNA binding
AM440_RS13300	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AM440_RS13305	COG2315	Protein conserved in bacteria
AM440_RS13310	COG0432	Pfam Uncharacterised protein family UPF0047
AM440_RS13315	COG3700	Belongs to the class B bacterial acid phosphatase family
AM440_RS13330	COG1448	Aminotransferase
AM440_RS13335	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AM440_RS13340	COG0305	Participates in initiation and elongation during chromosome replication
AM440_RS13345	COG0604	alcohol dehydrogenase
AM440_RS13355	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM440_RS13370	COG0735	belongs to the Fur family
AM440_RS13375	COG3237	CsbD-like
AM440_RS13380	COG0534	Mate efflux family protein
AM440_RS13390	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AM440_RS13415	COG1357	PFAM Pentapeptide repeats (8 copies)
AM440_RS13435	COG3842	ATPase activity
AM440_RS13445	COG2182	Extracellular solute-binding protein
AM440_RS13450	COG1175	transmembrane transport
AM440_RS13455	COG3833	ABC-type maltose transport systems, permease component
AM440_RS13465	COG2814	Major facilitator Superfamily
AM440_RS13465	COG0477	Major facilitator Superfamily
AM440_RS13480	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM440_RS13515	COG0527	aspartate kinase activity
AM440_RS13525	COG1187	pseudouridine synthase activity
AM440_RS13535	COG1283	sodium-dependent phosphate transmembrane transporter activity
AM440_RS13540	COG1410	methionine synthase
AM440_RS13540	COG0646	methionine synthase
AM440_RS13545	COG1414	Transcriptional regulator
AM440_RS13560	COG2224	Isocitrate lyase
AM440_RS13565	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AM440_RS13575	COG0456	acetyltransferase
AM440_RS13610	COG0151	Belongs to the GarS family
AM440_RS13615	COG2204	response regulator
AM440_RS13620	COG4191	Histidine kinase
AM440_RS13630	COG3678	ATP-independent chaperone mediated protein folding
AM440_RS13645	COG3068	Protein conserved in bacteria
AM440_RS13680	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AM440_RS13685	COG2104	thiamine diphosphate biosynthetic process
AM440_RS13695	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AM440_RS13740	COG0250	Participates in transcription elongation, termination and antitermination
AM440_RS13745	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AM440_RS13790	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AM440_RS13790	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AM440_RS13830	COG4206	TonB-dependent receptor
AM440_RS13860	COG0583	DNA-binding transcription factor activity
AM440_RS13875	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AM440_RS13890	COG2194	sulfuric ester hydrolase activity
AM440_RS13895	COG2207	Transcriptional regulator
AM440_RS13900	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM440_RS13905	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM440_RS13910	COG1882	Formate acetyltransferase
AM440_RS13915	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM440_RS13920	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM440_RS13925	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM440_RS13925	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM440_RS13925	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM440_RS13930	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM440_RS13935	COG0371	Dehydrogenase
AM440_RS13940	COG3738	Protein conserved in bacteria
AM440_RS13945	COG0697	spore germination
AM440_RS13955	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AM440_RS13960	COG0460	homoserine dehydrogenase
AM440_RS13960	COG0527	aspartate kinase activity
AM440_RS13965	COG0626	cystathionine gamma-synthase activity
AM440_RS13980	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
AM440_RS13995	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AM440_RS14000	COG1609	Transcriptional regulator
AM440_RS14005	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AM440_RS14020	COG1575	Belongs to the MenA family. Type 1 subfamily
AM440_RS14035	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AM440_RS14045	COG1494	fructose-1,6-bisphosphatase
AM440_RS14050	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM440_RS14055	COG0589	response to stress
AM440_RS14060	COG3691	Protein conserved in bacteria
AM440_RS14065	COG3152	Membrane
AM440_RS14090	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AM440_RS14105	COG3678	ATP-independent chaperone mediated protein folding
AM440_RS14110	COG0745	RESPONSE REGULATOR receiver
AM440_RS14115	COG2205	protein histidine kinase activity
AM440_RS14120	COG2258	MOSC domain
AM440_RS14135	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AM440_RS14175	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM440_RS14180	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM440_RS14180	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM440_RS14185	COG1363	Peptidase, m42
AM440_RS14190	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM440_RS14190	COG3711	transcriptional antiterminator
AM440_RS14210	COG3383	formate dehydrogenase (NAD+) activity
AM440_RS14210	COG0243	molybdopterin cofactor binding
AM440_RS14215	COG3383	formate dehydrogenase (NAD+) activity
AM440_RS14215	COG0243	molybdopterin cofactor binding
AM440_RS14220	COG0437	4 iron, 4 sulfur cluster binding
AM440_RS14225	COG2864	formate dehydrogenase
AM440_RS14235	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AM440_RS14240	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AM440_RS14245	COG0456	acetyltransferase
AM440_RS14260	COG1011	Hydrolase
AM440_RS14265	COG1349	DNA-binding transcription factor activity
AM440_RS14270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM440_RS14275	COG2084	Dehydrogenase
AM440_RS14280	COG3684	Belongs to the aldolase LacD family
AM440_RS14285	COG2942	2-epimerase
AM440_RS14290	COG2942	2-epimerase
AM440_RS14295	COG2017	converts alpha-aldose to the beta-anomer
AM440_RS14300	COG1501	Belongs to the glycosyl hydrolase 31 family
AM440_RS14305	COG2211	Major facilitator Superfamily
AM440_RS14310	COG2211	Major facilitator Superfamily
AM440_RS14315	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AM440_RS14320	COG2271	Major facilitator Superfamily
AM440_RS14325	COG1082	Xylose isomerase domain protein TIM barrel
AM440_RS14340	COG1082	Xylose isomerase domain protein TIM barrel
AM440_RS14345	COG2188	Transcriptional regulator
AM440_RS14350	COG1217	gtp-binding protein TYPA
AM440_RS14360	COG0174	glutamine synthetase
AM440_RS14365	COG3852	Histidine kinase
AM440_RS14370	COG2204	response regulator
AM440_RS14380	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AM440_RS14395	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AM440_RS14395	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AM440_RS14405	COG0204	Acyl-transferase
AM440_RS14410	COG5339	Protein conserved in bacteria
AM440_RS14415	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM440_RS14420	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AM440_RS14425	COG3084	Protein conserved in bacteria
AM440_RS14430	COG0746	molybdenum cofactor guanylyltransferase activity
AM440_RS14435	COG1763	Mo-molybdopterin cofactor biosynthetic process
AM440_RS14465	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
AM440_RS14470	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AM440_RS14475	COG1739	Uncharacterized protein family UPF0029
AM440_RS14490	COG0183	Belongs to the thiolase family
AM440_RS14495	COG0543	2 iron, 2 sulfur cluster binding
AM440_RS14500	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AM440_RS14505	COG0250	Participates in transcription elongation, termination and antitermination
AM440_RS14510	COG0084	hydrolase, TatD family'
AM440_RS14515	COG0805	protein transport
AM440_RS14520	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AM440_RS14525	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AM440_RS14535	COG3165	ubiquinone biosynthetic process from chorismate
AM440_RS14545	COG1322	Protein conserved in bacteria
AM440_RS14550	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
AM440_RS14555	COG0412	Dienelactone hydrolase
AM440_RS14565	COG0583	DNA-binding transcription factor activity
AM440_RS14570	COG0697	spore germination
AM440_RS14575	COG0561	phosphatase activity
AM440_RS14580	COG2267	carboxylic ester hydrolase activity
AM440_RS14585	COG1280	lysine exporter protein (LysE YggA)
AM440_RS14590	COG1280	lysine exporter protein (LysE YggA)
AM440_RS14595	COG0514	ATP-dependent DNA helicase (RecQ)
AM440_RS14600	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
AM440_RS14605	COG2050	protein possibly involved in aromatic compounds catabolism
AM440_RS14610	COG2962	Rard protein
AM440_RS14625	COG0598	Magnesium transport protein CorA
AM440_RS14630	COG3698	Phosphodiester glycosidase
AM440_RS14635	COG0210	DNA helicase
AM440_RS14640	COG1011	Hydrolase
AM440_RS14650	COG3159	Protein conserved in bacteria
AM440_RS14660	COG5567	small periplasmic lipoprotein
AM440_RS14670	COG3072	Adenylate cyclase
AM440_RS14685	COG1587	Uroporphyrinogen-III synthase
AM440_RS14690	COG2959	enzyme of heme biosynthesis
AM440_RS14695	COG3071	HemY protein
AM440_RS14700	COG0641	radical SAM
AM440_RS14725	COG1113	amino acid transport
AM440_RS14745	COG2244	polysaccharide biosynthetic process
AM440_RS14750	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AM440_RS14755	COG0456	acetyltransferase
AM440_RS14765	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AM440_RS14770	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AM440_RS14775	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
AM440_RS14780	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AM440_RS14790	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AM440_RS14800	COG3118	belongs to the thioredoxin family
AM440_RS14820	COG0210	DNA helicase
AM440_RS14825	COG3692	DNA binding
AM440_RS14830	COG3692	DNA binding
AM440_RS14835	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM440_RS14845	COG0583	DNA-binding transcription factor activity
AM440_RS14850	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AM440_RS14860	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AM440_RS14865	COG3978	acetolactate synthase activity
AM440_RS14880	COG0606	chelatase, subunit chli
AM440_RS14885	COG3085	chromosome segregation
AM440_RS14925	COG2186	Transcriptional regulator
AM440_RS14930	COG0477	Major facilitator Superfamily
AM440_RS14935	COG1609	Transcriptional regulator
AM440_RS14940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM440_RS14945	COG1879	ABC-type sugar transport system periplasmic component
AM440_RS14950	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM440_RS14955	COG1129	ABC transporter
AM440_RS14985	COG1522	sequence-specific DNA binding
AM440_RS14990	COG0716	FMN binding
AM440_RS15005	COG3312	ion transport
AM440_RS15065	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AM440_RS15070	COG0573	inorganic phosphate transmembrane transporter activity
AM440_RS15075	COG0581	inorganic phosphate transmembrane transporter activity
AM440_RS15080	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AM440_RS15085	COG0704	Plays a role in the regulation of phosphate uptake
AM440_RS15090	COG3711	transcriptional antiterminator
AM440_RS15095	COG2190	(PTS) system
AM440_RS15095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM440_RS15095	COG1263	PTS System
AM440_RS15100	COG2723	6-phospho-beta-galactosidase activity
AM440_RS15110	COG2382	esterase
AM440_RS15115	COG0363	glucosamine-6-phosphate deaminase activity
AM440_RS15120	COG3196	Protein conserved in bacteria
AM440_RS15130	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM440_RS15135	COG2252	PERMEase
AM440_RS15140	COG0431	NADPH-dependent FMN reductase
AM440_RS15145	COG2091	lysine biosynthetic process via aminoadipic acid
AM440_RS15160	COG0814	amino acid
AM440_RS15210	COG0592	DNA-directed DNA polymerase activity
AM440_RS15220	COG0187	DNA topoisomerase II activity
AM440_RS15225	COG3753	Protein conserved in bacteria
AM440_RS15230	COG0561	phosphatase activity
AM440_RS15240	COG2186	Transcriptional regulator
AM440_RS15245	COG3734	2-keto-3-deoxy-galactonokinase
AM440_RS15250	COG0800	Aldolase
AM440_RS15260	COG2271	Major facilitator Superfamily
AM440_RS15265	COG0644	oxidoreductase
AM440_RS15270	COG0823	Involved in the tonB-independent uptake of proteins
AM440_RS15275	COG5645	(Lipo)protein
AM440_RS15310	COG2207	Transcriptional regulator
AM440_RS15315	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AM440_RS15320	COG3119	arylsulfatase activity
AM440_RS15330	COG2149	membrane
AM440_RS15340	COG0641	radical SAM
AM440_RS15345	COG2814	Major facilitator Superfamily
AM440_RS15380	COG0028	Belongs to the TPP enzyme family
AM440_RS15385	COG0440	acetolactate synthase activity
AM440_RS15390	COG2197	response regulator
AM440_RS15395	COG3851	Histidine kinase
AM440_RS15400	COG2271	Major facilitator Superfamily
AM440_RS15405	COG2271	Major facilitator Superfamily
AM440_RS15415	COG2252	PERMEase
AM440_RS15445	COG1464	Belongs to the NlpA lipoprotein family
AM440_RS15450	COG0697	spore germination
AM440_RS15455	COG2814	Major facilitator Superfamily
AM440_RS15560	COG0582	viral genome integration into host DNA
AM440_RS15570	COG2211	Major facilitator Superfamily
AM440_RS15580	COG2982	Protein involved in outer membrane biogenesis
AM440_RS15585	COG2233	PERMEase
AM440_RS15590	COG0786	glutamate:sodium symporter activity
AM440_RS15595	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AM440_RS15600	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM440_RS15605	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM440_RS15615	COG0194	GDP metabolic process
AM440_RS15625	COG2860	membrane
AM440_RS15635	COG3645	SOS response
AM440_RS15640	COG1561	YicC-like family, N-terminal region
AM440_RS15670	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AM440_RS15700	COG1519	Transferase
AM440_RS15705	COG0859	PFAM glycosyl transferase family 9
AM440_RS15710	COG0438	transferase activity, transferring glycosyl groups
AM440_RS15715	COG0515	serine threonine protein kinase
AM440_RS15730	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AM440_RS15735	COG1442	glycosyl transferase family 8
AM440_RS15740	COG1216	Glycosyl transferase, family 2
AM440_RS15745	COG3307	-O-antigen
AM440_RS15750	COG0859	PFAM glycosyl transferase family 9
AM440_RS15755	COG0859	PFAM glycosyl transferase family 9
AM440_RS15765	COG0156	8-amino-7-oxononanoate synthase activity
AM440_RS15775	COG1216	Glycosyl transferase, family 2
AM440_RS15780	COG2861	carbohydrate metabolic process
AM440_RS15785	COG4942	peptidase
AM440_RS15800	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AM440_RS15805	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM440_RS15820	COG1045	serine acetyltransferase
AM440_RS15825	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AM440_RS15835	COG2186	Transcriptional regulator
AM440_RS15840	COG1620	l-lactate permease
AM440_RS15850	COG5295	Hep Hag repeat protein
AM440_RS15875	COG3722	fumarate hydratase activity
AM440_RS15885	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM440_RS15885	COG2213	PTS system mannitol-specific
AM440_RS15895	COG1566	PFAM secretion protein HlyD family protein
AM440_RS15930	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AM440_RS15935	COG3209	COG3209 Rhs family protein
AM440_RS15940	COG1413	lyase activity
AM440_RS15945	COG3209	COG3209 Rhs family protein
AM440_RS15950	COG0625	glutathione transferase activity
AM440_RS15960	COG3276	selenocysteine insertion sequence binding
AM440_RS15965	COG1454	alcohol dehydrogenase
AM440_RS15970	COG1012	belongs to the aldehyde dehydrogenase family
AM440_RS15985	COG1566	PFAM secretion protein HlyD family protein
AM440_RS15990	COG0583	DNA-binding transcription factor activity
AM440_RS15995	COG3713	MltA-interacting MipA family protein
AM440_RS16000	COG0235	Class ii aldolase
AM440_RS16005	COG3623	hexulose-6-phosphate isomerase
AM440_RS16010	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AM440_RS16015	COG1070	Carbohydrate kinase
AM440_RS16020	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AM440_RS16025	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AM440_RS16030	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AM440_RS16035	COG2731	YhcH YjgK YiaL family protein
AM440_RS16045	COG1414	Transcriptional regulator
AM440_RS16050	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM440_RS16055	COG3977	Valine--pyruvate aminotransferase
AM440_RS16060	COG0366	Alpha amylase catalytic
AM440_RS16065	COG2992	FlgJ-related protein
AM440_RS16070	COG2207	Transcriptional regulator
AM440_RS16070	COG1609	Transcriptional regulator
AM440_RS16075	COG4214	carbohydrate transport
AM440_RS16080	COG1129	ABC transporter
AM440_RS16085	COG4213	ABC transporter substrate-binding protein
AM440_RS16095	COG1070	Carbohydrate kinase
AM440_RS16100	COG4682	membrane
AM440_RS16105	COG4682	membrane
AM440_RS16110	COG3274	enterobacterial common antigen metabolic process
AM440_RS16140	COG1278	Cold shock
AM440_RS16145	COG2944	sequence-specific DNA binding
AM440_RS16160	COG2885	chlorophyll binding
AM440_RS16165	COG0243	molybdopterin cofactor binding
AM440_RS16170	COG0456	acetyltransferase
AM440_RS16175	COG2818	Glycosylase
AM440_RS16190	COG2223	nitrite transmembrane transporter activity
AM440_RS16195	COG2194	sulfuric ester hydrolase activity
AM440_RS16215	COG0747	negative chemotaxis
AM440_RS16225	COG0601	transmembrane transport
AM440_RS16230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM440_RS16235	COG0444	Belongs to the ABC transporter superfamily
AM440_RS16240	COG4608	Belongs to the ABC transporter superfamily
AM440_RS16245	COG0814	amino acid
AM440_RS16300	COG2194	sulfuric ester hydrolase activity
AM440_RS16325	COG1215	transferase activity, transferring glycosyl groups
AM440_RS16330	COG1215	transferase activity, transferring glycosyl groups
AM440_RS16335	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AM440_RS16340	COG3118	belongs to the thioredoxin family
AM440_RS16340	COG0457	Tetratricopeptide repeat
AM440_RS16345	COG2199	diguanylate cyclase activity
AM440_RS16345	COG2200	EAL domain
AM440_RS16365	COG0612	Peptidase, M16
AM440_RS16370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM440_RS16380	COG2200	EAL domain
AM440_RS16385	COG2982	Protein involved in outer membrane biogenesis
AM440_RS16390	COG0477	Major facilitator Superfamily
AM440_RS16395	COG1295	ribonuclease BN
AM440_RS16400	COG0583	DNA-binding transcription factor activity
AM440_RS16405	COG2197	response regulator
AM440_RS16415	COG1858	cytochrome C peroxidase
AM440_RS16420	COG0076	glutamate decarboxylase activity
AM440_RS16430	COG2207	Transcriptional regulator
AM440_RS16440	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM440_RS16445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM440_RS16455	COG2771	luxR family
AM440_RS16460	COG3247	response to pH
AM440_RS16475	COG1285	pathogenesis
AM440_RS16480	COG2197	response regulator
AM440_RS16490	COG3065	identical protein binding
AM440_RS16500	COG1393	Belongs to the ArsC family
AM440_RS16505	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AM440_RS16510	COG0640	Transcriptional regulator
AM440_RS16525	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM440_RS16530	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AM440_RS16535	COG0339	signal peptide processing
AM440_RS16545	COG3104	oligopeptide transport
AM440_RS16555	COG0589	response to stress
AM440_RS16565	COG0306	phosphate transporter
AM440_RS16570	COG2081	HI0933 family
AM440_RS16595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM440_RS16600	COG0842	Transport permease protein
AM440_RS16600	COG1129	ABC transporter
AM440_RS16605	COG0842	Transport permease protein
AM440_RS16610	COG5433	transposase activity
AM440_RS16615	COG1413	lyase activity
AM440_RS16625	COG3209	COG3209 Rhs family protein
AM440_RS16635	COG1124	(ABC) transporter
AM440_RS16640	COG0444	Belongs to the ABC transporter superfamily
AM440_RS16645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM440_RS16650	COG0601	transmembrane transport
AM440_RS16655	COG0747	negative chemotaxis
AM440_RS16660	COG2091	lysine biosynthetic process via aminoadipic acid
AM440_RS16665	COG0628	permease
AM440_RS16670	COG0477	Major facilitator Superfamily
AM440_RS16680	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AM440_RS16695	COG3714	YhhN family
AM440_RS16705	COG3776	membrane
AM440_RS16710	COG0742	ribosomal rna small subunit methyltransferase
AM440_RS16715	COG0552	protein localization to endoplasmic reticulum
AM440_RS16720	COG2884	Cell division ATP-binding protein ftsE
AM440_RS16725	COG2177	Part of the ABC transporter FtsEX involved in
AM440_RS16730	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM440_RS16735	COG0683	leucine binding
AM440_RS16740	COG0456	acetyltransferase
AM440_RS16750	COG0683	leucine binding
AM440_RS16755	COG0559	Belongs to the binding-protein-dependent transport system permease family
AM440_RS16760	COG4177	L-phenylalanine transmembrane transporter activity
AM440_RS16765	COG0411	ABC transporter
AM440_RS16770	COG0410	ABC transporter
AM440_RS16775	COG1653	transport
AM440_RS16780	COG1175	transmembrane transport
AM440_RS16790	COG3842	ATPase activity
AM440_RS16795	COG0584	glycerophosphoryl diester phosphodiesterase
AM440_RS16805	COG0405	Gamma-glutamyltransferase
AM440_RS16825	COG3157	Type VI secretion system effector, Hcp
AM440_RS16830	COG1247	-acetyltransferase
AM440_RS16840	COG0673	inositol 2-dehydrogenase activity
AM440_RS16845	COG1741	Belongs to the pirin family
AM440_RS16850	COG1609	Transcriptional regulator
AM440_RS16855	COG3265	gluconokinase activity
AM440_RS16860	COG2610	gluconate transmembrane transporter activity
AM440_RS16865	COG2095	MarC family integral membrane protein
AM440_RS16870	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AM440_RS16895	COG0058	SHG alpha-glucan phosphorylase activity
AM440_RS16900	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AM440_RS16920	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AM440_RS16935	COG1349	DNA-binding transcription factor activity
AM440_RS16940	COG4650	regulator
AM440_RS16945	COG1690	Belongs to the RtcB family
AM440_RS16960	COG0058	SHG alpha-glucan phosphorylase activity
AM440_RS16965	COG1640	4-alpha-glucanotransferase
AM440_RS16970	COG2610	gluconate transmembrane transporter activity
AM440_RS16990	COG5464	transposase or invertase
AM440_RS17005	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AM440_RS17010	COG1918	ferrous iron import across plasma membrane
AM440_RS17020	COG2183	response to ionizing radiation
AM440_RS17025	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AM440_RS17055	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AM440_RS17065	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AM440_RS17070	COG1011	Hydrolase
AM440_RS17080	COG0494	nUDIX hydrolase
AM440_RS17085	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AM440_RS17090	COG4972	Pilus assembly protein
AM440_RS17095	COG3166	PFAM Fimbrial assembly family protein
AM440_RS17110	COG4796	Type ii and iii secretion system protein
AM440_RS17125	COG3266	domain, Protein
AM440_RS17130	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AM440_RS17135	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AM440_RS17140	COG0546	phosphoglycolate phosphatase activity
AM440_RS17145	COG0180	Tryptophanyl-tRNA synthetase
AM440_RS17155	COG2188	Transcriptional regulator
AM440_RS17165	COG3457	Alanine racemase
AM440_RS17170	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AM440_RS17175	COG1735	metal-dependent hydrolase with the TIM-barrel fold
AM440_RS17190	COG0626	cystathionine gamma-synthase activity
AM440_RS17195	COG2188	Transcriptional regulator
AM440_RS17200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM440_RS17205	COG1082	Xylose isomerase domain protein TIM barrel
AM440_RS17210	COG1082	Xylose isomerase domain protein TIM barrel
AM440_RS17215	COG2222	sugar isomerase
AM440_RS17220	COG0531	amino acid
AM440_RS17235	COG2116	formate transmembrane transporter activity
AM440_RS17240	COG2146	nitrite reductase [NAD(P)H] activity
AM440_RS17245	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM440_RS17255	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AM440_RS17265	COG2184	nucleotidyltransferase activity
AM440_RS17270	COG0512	Glutamine amidotransferase of anthranilate synthase
AM440_RS17275	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AM440_RS17280	COG1289	transmembrane transporter activity
AM440_RS17285	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM440_RS17295	COG1765	OsmC-like protein
AM440_RS17300	COG3954	Phosphoribulokinase
AM440_RS17310	COG0429	hydrolase of the alpha beta-hydrolase fold
AM440_RS17315	COG0488	(ABC) transporter
AM440_RS17335	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AM440_RS17340	COG1047	Peptidyl-prolyl cis-trans
AM440_RS17350	COG0545	Peptidyl-prolyl cis-trans isomerase
AM440_RS17355	COG2964	Protein conserved in bacteria
AM440_RS17395	COG3979	chitinase
AM440_RS17400	COG2906	2 iron, 2 sulfur cluster binding
AM440_RS17405	COG2193	ferroxidase activity
AM440_RS17410	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AM440_RS17415	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AM440_RS17420	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AM440_RS17425	COG3156	type II secretion system protein K
AM440_RS17430	COG4795	General secretion pathway protein
AM440_RS17435	COG2165	general secretion pathway protein
AM440_RS17440	COG2165	general secretion pathway protein
AM440_RS17445	COG2165	general secretion pathway protein
AM440_RS17450	COG1459	type II secretion system
AM440_RS17455	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AM440_RS17460	COG1450	Type ii and iii secretion system protein
AM440_RS17465	COG3031	protein transport across the cell outer membrane
AM440_RS17470	COG3267	Type II secretory pathway component ExeA
AM440_RS17470	COG3409	Peptidoglycan-binding domain 1 protein
AM440_RS17495	COG0089	rRNA binding
AM440_RS17585	COG0201	protein transport
AM440_RS17625	COG0789	Transcriptional regulator
AM440_RS17630	COG3036	rescue of stalled ribosome
AM440_RS17640	COG0569	domain protein
AM440_RS17660	COG0758	DNA mediated transformation
AM440_RS17670	COG0551	DNA topoisomerase type I activity
AM440_RS17690	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM440_RS17730	COG1126	abc transporter atp-binding protein
AM440_RS17735	COG0765	amino acid transport
AM440_RS17740	COG4597	amino acid ABC transporter
AM440_RS17745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM440_RS17765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM440_RS17775	COG1309	transcriptional regulator
AM440_RS17785	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AM440_RS17795	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM440_RS17805	COG4145	pantothenate transmembrane transporter activity
AM440_RS17810	COG3924	membrane
AM440_RS17815	COG0439	Biotin carboxylase
AM440_RS17820	COG0511	ligase activity, forming carbon-carbon bonds
AM440_RS17830	COG0604	alcohol dehydrogenase
AM440_RS17835	COG2199	diguanylate cyclase activity
AM440_RS17835	COG2200	EAL domain
AM440_RS17850	COG1077	Cell shape determining protein MreB Mrl
AM440_RS17855	COG1792	Involved in formation and maintenance of cell shape
AM440_RS17860	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AM440_RS17870	COG1530	ribonuclease E activity
AM440_RS17875	COG3164	Protein of unknown function
AM440_RS17880	COG0312	modulator of DNA gyrase
AM440_RS17885	COG0583	DNA-binding transcription factor activity
AM440_RS17905	COG2732	(Barnase) inhibitor
AM440_RS17925	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM440_RS17930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM440_RS17935	COG3105	Protein conserved in bacteria
AM440_RS17940	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AM440_RS17960	COG0625	glutathione transferase activity
AM440_RS17965	COG2969	positive regulation of protein catabolic process
AM440_RS17970	COG3069	C4-dicarboxylate transmembrane transporter activity
AM440_RS18005	COG2731	YhcH YjgK YiaL family protein
AM440_RS18015	COG4804	nuclease activity
AM440_RS18020	COG0493	'glutamate synthase
AM440_RS18025	COG0070	glutamate synthase
AM440_RS18025	COG0069	glutamate synthase activity
AM440_RS18025	COG0067	glutamate synthase
AM440_RS18040	COG1242	4 iron, 4 sulfur cluster binding
AM440_RS18045	COG5002	protein histidine kinase activity
AM440_RS18045	COG0784	Response regulator, receiver
AM440_RS18045	COG2198	Histidine kinase
AM440_RS18050	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AM440_RS18060	COG0515	serine threonine protein kinase
AM440_RS18065	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM440_RS18080	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AM440_RS18085	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AM440_RS18090	COG1137	ATPase activity
AM440_RS18095	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AM440_RS18100	COG3117	lipopolysaccharide transmembrane transporter activity
AM440_RS18105	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AM440_RS18110	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AM440_RS18110	COG0517	IMP dehydrogenase activity
AM440_RS18115	COG0530	calcium, potassium:sodium antiporter activity
AM440_RS18120	COG1127	ABC transporter
AM440_RS18125	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AM440_RS18130	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AM440_RS18135	COG2854	intermembrane phospholipid transfer
AM440_RS18140	COG3113	response to antibiotic
AM440_RS18145	COG5007	Belongs to the BolA IbaG family
AM440_RS18155	COG3423	Transcriptional regulator
AM440_RS18160	COG0142	geranyltranstransferase activity
AM440_RS18175	COG0697	spore germination
AM440_RS18185	COG2027	D-alanyl-D-alanine carboxypeptidase
AM440_RS18190	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AM440_RS18195	COG1534	Rna-binding protein
AM440_RS18205	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM440_RS18210	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AM440_RS18220	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AM440_RS18235	COG2194	sulfuric ester hydrolase activity
AM440_RS18255	COG0195	Participates in both transcription termination and antitermination
AM440_RS18295	COG0513	Belongs to the DEAD box helicase family
AM440_RS18300	COG0814	amino acid
AM440_RS18305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM440_RS18310	COG0826	peptidase U32
AM440_RS18315	COG0826	peptidase U32
AM440_RS18320	COG3154	lipid carrier protein
AM440_RS18325	COG3153	acetyltransferase
AM440_RS18340	COG0693	protein deglycase activity
AM440_RS18345	COG0702	epimerase
AM440_RS18350	COG0701	Predicted permease
AM440_RS18355	COG2823	Periplasmic or secreted lipoprotein
AM440_RS18370	COG3107	peptidoglycan biosynthetic process
AM440_RS18375	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AM440_RS18380	COG3539	Fimbrial protein
AM440_RS18385	COG3188	usher protein
AM440_RS18390	COG3121	Chaperone
AM440_RS18395	COG3539	Fimbrial protein
AM440_RS18400	COG0363	glucosamine-6-phosphate deaminase activity
AM440_RS18405	COG3716	PTS system mannose fructose sorbose family IID component
AM440_RS18410	COG3715	PTS system
AM440_RS18415	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM440_RS18425	COG2222	sugar isomerase
AM440_RS18430	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AM440_RS18435	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM440_RS18440	COG3716	PTS system mannose fructose sorbose family IID component
AM440_RS18450	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM440_RS18465	COG1349	DNA-binding transcription factor activity
AM440_RS18475	COG2002	toxin-antitoxin pair type II binding
AM440_RS18480	COG2721	sulfolactate sulfo-lyase activity
AM440_RS18485	COG2271	Major facilitator Superfamily
AM440_RS18495	COG2084	Dehydrogenase
AM440_RS18500	COG1929	Belongs to the glycerate kinase type-1 family
AM440_RS18530	COG0583	DNA-binding transcription factor activity
AM440_RS18535	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AM440_RS18545	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AM440_RS18550	COG1882	Formate acetyltransferase
AM440_RS18555	COG0251	oxidation-reduction process
AM440_RS18560	COG1760	l-serine dehydratase
AM440_RS18565	COG0814	amino acid
AM440_RS18580	COG1741	Belongs to the pirin family
AM440_RS18585	COG0583	DNA-binding transcription factor activity
AM440_RS18595	COG3152	Membrane
AM440_RS18600	COG3152	Membrane
AM440_RS18605	COG0435	Glutathione S-transferase
AM440_RS18610	COG2259	Doxx family
AM440_RS18620	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
AM440_RS18625	COG4575	ribosome binding
AM440_RS18630	COG1422	Protein of unknown function (DUF1090)
AM440_RS18640	COG0586	Pfam SNARE associated Golgi protein
AM440_RS18645	COG2186	Transcriptional regulator
AM440_RS18665	COG2271	Major facilitator Superfamily
AM440_RS18675	COG2721	sulfolactate sulfo-lyase activity
AM440_RS18685	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AM440_RS18690	COG0861	Integral membrane protein TerC family
AM440_RS18695	COG0673	inositol 2-dehydrogenase activity
AM440_RS18700	COG2949	membrane
AM440_RS18705	COG1451	nucleotide metabolic process
AM440_RS18720	COG4680	protein conserved in bacteria
AM440_RS18725	COG5499	transcription regulator containing HTH domain
AM440_RS18730	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM440_RS18730	COG1902	pentaerythritol trinitrate reductase activity
AM440_RS18735	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
AM440_RS18735	COG3408	Glycogen debranching enzyme
AM440_RS18745	COG0531	amino acid
AM440_RS18750	COG2731	YhcH YjgK YiaL family protein
AM440_RS18755	COG3250	beta-galactosidase activity
AM440_RS18760	COG1609	Transcriptional regulator
AM440_RS18770	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM440_RS18785	COG0840	transmembrane signaling receptor activity
AM440_RS18790	COG1695	Transcriptional regulator
AM440_RS18800	COG2375	cellular response to nickel ion
AM440_RS18815	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM440_RS18825	COG0358	DNA primase activity
AM440_RS18830	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AM440_RS18845	COG0471	metal ion transport
AM440_RS18850	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AM440_RS18855	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AM440_RS18865	COG0583	DNA-binding transcription factor activity
AM440_RS18875	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AM440_RS18890	COG4991	sh3 domain protein
AM440_RS18900	COG3025	triphosphatase activity
AM440_RS18915	COG2268	Band 7 protein
AM440_RS18920	COG1585	Membrane protein implicated in regulation of membrane protease activity
AM440_RS18930	COG3539	Fimbrial protein
AM440_RS18935	COG3121	Chaperone
AM440_RS18940	COG3121	Chaperone
AM440_RS18945	COG3188	usher protein
AM440_RS18950	COG3539	Fimbrial protein
AM440_RS18955	COG2960	long-chain fatty acid transporting porin activity
AM440_RS18975	COG3384	dioxygenase
AM440_RS18980	COG0754	glutathionylspermidine amidase activity
AM440_RS18995	COG1538	Outer membrane efflux protein
AM440_RS19000	COG0494	nUDIX hydrolase
AM440_RS19005	COG3151	Protein conserved in bacteria
AM440_RS19010	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AM440_RS19015	COG3150	esterase
AM440_RS19020	COG0187	DNA topoisomerase II activity
AM440_RS19025	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AM440_RS19030	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM440_RS19040	COG0642	Histidine kinase
AM440_RS19045	COG0745	RESPONSE REGULATOR receiver
AM440_RS19050	COG3111	PFAM Bacterial OB fold (BOF) protein
AM440_RS19055	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AM440_RS19065	COG2944	sequence-specific DNA binding
AM440_RS19070	COG4166	transmembrane transport
AM440_RS19075	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AM440_RS19080	COG0204	Acyl-transferase
AM440_RS19085	COG2132	Multicopper oxidase
AM440_RS19090	COG1032	radical SAM domain protein
AM440_RS19095	COG4238	major outer membrane lipoprotein
AM440_RS19105	COG0656	L-ascorbic acid biosynthetic process
AM440_RS19110	COG1979	alcohol dehydrogenase
AM440_RS19115	COG2207	Transcriptional regulator
AM440_RS19120	COG0586	Pfam SNARE associated Golgi protein
AM440_RS19125	COG0626	cystathionine gamma-synthase activity
AM440_RS19135	COG0811	peptide transport
AM440_RS19140	COG0848	biopolymer transport protein
AM440_RS19145	COG1028	Short-chain dehydrogenase reductase Sdr
AM440_RS19180	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AM440_RS19185	COG0437	4 iron, 4 sulfur cluster binding
AM440_RS19190	COG5557	Pfam Polysulphide reductase, NrfD
AM440_RS19195	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AM440_RS19200	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AM440_RS19205	COG1773	rubredoxin
AM440_RS19215	COG0298	carbon dioxide binding
AM440_RS19220	COG0625	glutathione transferase activity
AM440_RS19225	COG0754	glutathionylspermidine amidase activity
AM440_RS19230	COG0306	phosphate transporter
AM440_RS19235	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AM440_RS19240	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AM440_RS19245	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AM440_RS19250	COG2244	polysaccharide biosynthetic process
AM440_RS19260	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AM440_RS19265	COG0795	lipopolysaccharide-transporting ATPase activity
AM440_RS19275	COG0156	8-amino-7-oxononanoate synthase activity
AM440_RS19280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AM440_RS19290	COG0318	PFAM AMP-dependent synthetase and ligase
AM440_RS19300	COG0456	acetyltransferase
AM440_RS19305	COG2186	Transcriptional regulator
AM440_RS19310	COG0277	FAD linked oxidase domain protein
AM440_RS19315	COG0277	FAD linked oxidase domain protein
AM440_RS19320	COG0247	lactate metabolic process
AM440_RS19325	COG3193	protein, possibly involved in utilization of glycolate and propanediol
AM440_RS19335	COG1620	l-lactate permease
AM440_RS19355	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AM440_RS19360	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AM440_RS19390	COG2165	general secretion pathway protein
AM440_RS19395	COG1459	type II secretion system
AM440_RS19400	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AM440_RS19405	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AM440_RS19415	COG1811	Na channel or pump
AM440_RS19425	COG1982	Orn Lys Arg decarboxylase major
AM440_RS19430	COG2211	Major facilitator Superfamily
AM440_RS19445	COG1194	a g-specific adenine glycosylase
AM440_RS19460	COG3171	Protein conserved in bacteria
AM440_RS19470	COG0252	asparaginase activity
AM440_RS19480	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AM440_RS19485	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AM440_RS19495	COG0762	integral membrane protein
AM440_RS19500	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AM440_RS19505	COG2805	Type II/IV secretion system protein
AM440_RS19520	COG0189	ligase activity
AM440_RS19525	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AM440_RS19530	COG2356	endonuclease I
AM440_RS19540	COG2814	Major facilitator Superfamily
AM440_RS19565	COG1166	arginine decarboxylase activity
AM440_RS19575	COG0501	Belongs to the peptidase M48B family
AM440_RS19580	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AM440_RS19585	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM440_RS19590	COG2213	PTS system mannitol-specific
AM440_RS19595	COG1063	alcohol dehydrogenase
AM440_RS19600	COG1494	fructose-1,6-bisphosphatase
AM440_RS19605	COG3722	fumarate hydratase activity
AM440_RS19610	COG1072	(Pantothenic acid kinase))
AM440_RS19630	COG0191	fructose-bisphosphate aldolase activity
AM440_RS19635	COG0668	transmembrane transport
AM440_RS19640	COG1279	arginine transmembrane transporter activity
AM440_RS19645	COG2968	Membrane
AM440_RS19650	COG0583	DNA-binding transcription factor activity
AM440_RS19655	COG0427	acetyl-CoA hydrolase
AM440_RS19660	COG1024	Enoyl-CoA hydratase
AM440_RS19665	COG1703	isobutyryl-CoA mutase activity
AM440_RS19670	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AM440_RS19670	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AM440_RS19695	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM440_RS19705	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AM440_RS19730	COG0006	proline dipeptidase activity
AM440_RS19735	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM440_RS19740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM440_RS19760	COG2723	6-phospho-beta-galactosidase activity
AM440_RS19770	COG1272	protein, Hemolysin III
AM440_RS19780	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AM440_RS19790	COG0716	FMN binding
AM440_RS19795	COG4974	Belongs to the 'phage' integrase family
AM440_RS19800	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM440_RS19805	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AM440_RS19830	COG2233	PERMEase
AM440_RS19840	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM440_RS19840	COG0493	'glutamate synthase
AM440_RS19845	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM440_RS19850	COG2252	PERMEase
AM440_RS19855	COG0402	S-adenosylhomocysteine deaminase activity
AM440_RS19860	COG2233	PERMEase
AM440_RS19865	COG2080	2 iron, 2 sulfur cluster binding
AM440_RS19865	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AM440_RS19870	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AM440_RS19875	COG0402	S-adenosylhomocysteine deaminase activity
AM440_RS19880	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM440_RS19880	COG0493	'glutamate synthase
AM440_RS19885	COG2068	MobA-Related Protein
AM440_RS19890	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AM440_RS19895	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AM440_RS19895	COG3608	succinylglutamate desuccinylase aspartoacylase
AM440_RS19900	COG0549	Belongs to the carbamate kinase family
AM440_RS19910	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AM440_RS19915	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AM440_RS19920	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AM440_RS19925	COG3829	transcription factor binding
AM440_RS19930	COG2080	2 iron, 2 sulfur cluster binding
AM440_RS19935	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AM440_RS19940	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AM440_RS19950	COG4942	peptidase
AM440_RS19960	COG3387	PFAM Glycoside hydrolase 15-related
AM440_RS20040	COG2197	response regulator
AM440_RS20055	COG0457	Tetratricopeptide repeat
AM440_RS20055	COG3710	Transcriptional regulator
AM440_RS20070	COG0457	Tetratricopeptide repeat
AM440_RS20110	COG3710	Transcriptional regulator
AM440_RS20115	COG2771	luxR family
AM440_RS20120	COG0814	amino acid
AM440_RS20125	COG0183	Belongs to the thiolase family
AM440_RS20135	COG1028	Short-chain dehydrogenase reductase Sdr
AM440_RS20140	COG2814	Major facilitator Superfamily
AM440_RS20145	COG1794	racemase activity, acting on amino acids and derivatives
AM440_RS20150	COG0583	DNA-binding transcription factor activity
AM440_RS20160	COG1609	Transcriptional regulator
AM440_RS20175	COG0667	Aldo Keto reductase
AM440_RS20185	COG0861	Integral membrane protein TerC family
AM440_RS20200	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
AM440_RS20215	COG2165	general secretion pathway protein
AM440_RS20220	COG4795	General secretion pathway protein
AM440_RS20230	COG4967	type IV pilus modification protein PilV
AM440_RS20235	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AM440_RS20240	COG1025	Belongs to the peptidase M16 family
AM440_RS20245	COG1074	ATP-dependent DNA helicase activity
AM440_RS20250	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AM440_RS20255	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AM440_RS20255	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AM440_RS20260	COG0860	N-Acetylmuramoyl-L-alanine amidase
AM440_RS20285	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AM440_RS20290	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AM440_RS20295	COG2166	iron-sulfur cluster assembly
AM440_RS20300	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AM440_RS20310	COG0583	DNA-binding transcription factor activity
AM440_RS20315	COG2363	Small membrane protein
AM440_RS20325	COG1349	DNA-binding transcription factor activity
AM440_RS20335	COG1070	Carbohydrate kinase
AM440_RS20345	COG0738	Major facilitator superfamily
AM440_RS20350	COG0235	Class ii aldolase
AM440_RS20355	COG1454	alcohol dehydrogenase
AM440_RS20365	COG1760	l-serine dehydratase
AM440_RS20370	COG0814	amino acid
AM440_RS20375	COG1611	Belongs to the LOG family
AM440_RS20390	COG3098	single-species biofilm formation
AM440_RS20395	COG0564	pseudouridine synthase activity
AM440_RS20400	COG0716	FMN binding
AM440_RS20405	COG2271	Major facilitator Superfamily
AM440_RS20410	COG4948	Mandelate Racemase Muconate Lactonizing
AM440_RS20415	COG4948	Mandelate Racemase Muconate Lactonizing
AM440_RS20420	COG3850	Histidine kinase
AM440_RS20420	COG3437	response regulator, receiver
AM440_RS20420	COG4999	Histidine kinase
AM440_RS20420	COG2205	protein histidine kinase activity
AM440_RS20425	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AM440_RS20430	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM440_RS20435	COG2336	PFAM SpoVT AbrB
AM440_RS20440	COG2337	Toxic component of a toxin-antitoxin (TA) module
AM440_RS20445	COG3956	TIGRFAM MazG family protein
AM440_RS20460	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AM440_RS20475	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AM440_RS20485	COG0602	queuosine metabolic process
AM440_RS20505	COG0277	FAD linked oxidase domain protein
AM440_RS20510	COG0477	Major facilitator Superfamily
AM440_RS20515	COG2086	electron transfer activity
AM440_RS20520	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AM440_RS20525	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AM440_RS20530	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AM440_RS20535	COG0644	oxidoreductase
AM440_RS20540	COG0720	synthase
AM440_RS20560	COG1203	CRISPR-associated helicase, Cas3
AM440_RS20575	COG1857	crispr-associated protein
AM440_RS20590	COG1518	maintenance of DNA repeat elements
AM440_RS20595	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM440_RS20600	COG2234	aminopeptidase activity
AM440_RS20655	COG1388	LysM domain
AM440_RS20655	COG4942	peptidase
AM440_RS20660	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM440_RS20665	COG2610	gluconate transmembrane transporter activity
AM440_RS20670	COG3622	Belongs to the hyi family
AM440_RS20675	COG0235	Class ii aldolase
AM440_RS20680	COG3395	kinase activity
AM440_RS20685	COG2084	Dehydrogenase
AM440_RS20690	COG1349	DNA-binding transcription factor activity
AM440_RS20695	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AM440_RS20715	COG3604	Transcriptional regulator
AM440_RS20720	COG0309	Hydrogenase expression formation protein (HypE)
AM440_RS20725	COG0409	Hydrogenase expression formation protein
AM440_RS20730	COG0298	carbon dioxide binding
AM440_RS20735	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AM440_RS20740	COG0375	protein maturation
AM440_RS20755	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM440_RS20760	COG0651	ATP synthesis coupled electron transport
AM440_RS20765	COG0650	Formate hydrogenlyase subunit 4
AM440_RS20770	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AM440_RS20770	COG3261	NADH dehydrogenase
AM440_RS20775	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM440_RS20780	COG3260	NADH ubiquinone oxidoreductase 20
AM440_RS20790	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AM440_RS20795	COG2723	6-phospho-beta-galactosidase activity
AM440_RS20800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM440_RS20800	COG1263	PTS System
AM440_RS20805	COG1609	Transcriptional regulator
AM440_RS20810	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM440_RS20815	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AM440_RS20835	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AM440_RS20835	COG0517	IMP dehydrogenase activity
AM440_RS20840	COG1349	DNA-binding transcription factor activity
AM440_RS20845	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM440_RS20850	COG1028	Short-chain dehydrogenase reductase Sdr
AM440_RS20855	COG3731	PTS system glucitol sorbitol-specific IIA component
AM440_RS20860	COG3732	PTS system glucitol sorbitol-specific
AM440_RS20865	COG3730	PTS system glucitol sorbitol-specific
AM440_RS20870	COG2951	lytic endotransglycosylase activity
AM440_RS20875	COG1546	Belongs to the CinA family
AM440_RS20895	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AM440_RS20925	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM440_RS20930	COG1238	metal cluster binding
AM440_RS20945	COG2814	Major facilitator Superfamily
AM440_RS20950	COG1566	PFAM secretion protein HlyD family protein
AM440_RS20955	COG1846	Transcriptional regulator
AM440_RS20965	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AM440_RS20970	COG2814	Major facilitator Superfamily
AM440_RS20975	COG2113	Glycine betaine
AM440_RS20980	COG4176	ABC-type proline glycine betaine transport system permease component
AM440_RS20985	COG4175	Glycine betaine
AM440_RS20995	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AM440_RS21000	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AM440_RS21010	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM440_RS21015	COG4575	ribosome binding
AM440_RS21030	COG2916	Histone family protein nucleoid-structuring protein H-NS
AM440_RS21035	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AM440_RS21040	COG0640	Transcriptional regulator
AM440_RS21045	COG0401	homolog of Blt101
AM440_RS21050	COG1652	LysM domain
AM440_RS21055	COG1802	Transcriptional regulator
AM440_RS21060	COG1113	amino acid transport
AM440_RS21065	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AM440_RS21070	COG1012	belongs to the aldehyde dehydrogenase family
AM440_RS21075	COG0579	oxidoreductase
AM440_RS21095	COG0366	Alpha amylase catalytic
AM440_RS21145	COG3468	outer membrane autotransporter barrel domain protein
AM440_RS21160	COG2867	negative regulation of translational initiation
AM440_RS21170	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM440_RS21175	COG0497	DNA recombination
AM440_RS21195	COG4536	flavin adenine dinucleotide binding
AM440_RS21200	COG4137	Cytochrome C assembly protein
AM440_RS21205	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AM440_RS21230	COG2885	chlorophyll binding
AM440_RS21235	COG2199	diguanylate cyclase activity
AM440_RS21255	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM440_RS21260	COG1605	Chorismate mutase
AM440_RS21260	COG0287	Prephenate dehydrogenase
AM440_RS21265	COG1605	Chorismate mutase
AM440_RS21265	COG0077	Prephenate dehydratase
AM440_RS21270	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AM440_RS21280	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM440_RS21285	COG0564	pseudouridine synthase activity
AM440_RS21290	COG1496	oxidoreductase activity
AM440_RS21295	COG0542	response to heat
AM440_RS21325	COG0477	Major facilitator Superfamily
AM440_RS21330	COG5544	Lipoprotein
AM440_RS21335	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM440_RS21340	COG0045	succinate-CoA ligase (ADP-forming) activity
AM440_RS21340	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM440_RS21340	COG1042	CoA-binding domain protein
AM440_RS21345	COG3148	PFAM DTW domain containing protein
AM440_RS21350	COG3118	belongs to the thioredoxin family
AM440_RS21360	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM440_RS21380	COG0583	DNA-binding transcription factor activity
AM440_RS21385	COG0513	Belongs to the DEAD box helicase family
AM440_RS21395	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AM440_RS21400	COG1595	DNA-templated transcription, initiation
AM440_RS21405	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
AM440_RS21410	COG3026	antisigma factor binding
AM440_RS21415	COG3086	response to oxidative stress
AM440_RS21425	COG0681	Belongs to the peptidase S26 family
AM440_RS21450	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AM440_RS21475	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM440_RS21480	COG1737	Transcriptional regulator
AM440_RS21485	COG0560	Phosphoserine phosphatase
AM440_RS21510	COG2205	protein histidine kinase activity
AM440_RS21515	COG3170	Tfp pilus assembly protein FimV
AM440_RS21520	COG2204	response regulator
AM440_RS21525	COG0347	Belongs to the P(II) protein family
AM440_RS21530	COG1017	nitric oxide dioxygenase activity
AM440_RS21530	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM440_RS21540	COG1940	carbohydrate kinase activity
AM440_RS21545	COG0457	Tetratricopeptide repeat
AM440_RS21550	COG1879	ABC-type sugar transport system periplasmic component
AM440_RS21555	COG1129	ABC transporter
AM440_RS21560	COG1129	ABC transporter
AM440_RS21565	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM440_RS21570	COG1063	alcohol dehydrogenase
AM440_RS21575	COG2017	converts alpha-aldose to the beta-anomer
AM440_RS21580	COG2259	Doxx family
AM440_RS21605	COG4638	Rieske (2fe-2S)
AM440_RS21610	COG0583	DNA-binding transcription factor activity
AM440_RS21615	COG2814	Major facilitator Superfamily
AM440_RS21620	COG3711	transcriptional antiterminator
AM440_RS21625	COG1073	alpha beta
AM440_RS21630	COG0483	inositol monophosphate 1-phosphatase activity
AM440_RS21650	COG0822	iron-sulfur transferase activity
AM440_RS21670	COG0633	Ferredoxin
AM440_RS21675	COG2975	iron-sulfur cluster assembly
AM440_RS21690	COG2897	thiosulfate sulfurtransferase activity
AM440_RS21695	COG2373	Large extracellular alpha-helical protein
AM440_RS21700	COG4953	penicillin-binding protein 1C
AM440_RS21730	COG2976	Protein conserved in bacteria
AM440_RS21745	COG1645	bacterial-type flagellum-dependent swarming motility
AM440_RS21755	COG0516	GMP reductase activity
AM440_RS21755	COG0517	IMP dehydrogenase activity
AM440_RS21770	COG3133	Outer membrane lipoprotein
AM440_RS21790	COG2200	EAL domain
AM440_RS21795	COG0248	Ppx GppA phosphatase
AM440_RS21800	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AM440_RS21805	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AM440_RS21825	COG2233	PERMEase
AM440_RS21835	COG1393	Belongs to the ArsC family
AM440_RS21840	COG4783	chaperone-mediated protein folding
AM440_RS21845	COG0628	permease
AM440_RS21850	COG2116	formate transmembrane transporter activity
AM440_RS21855	COG3604	Transcriptional regulator
AM440_RS21865	COG3260	NADH ubiquinone oxidoreductase 20
AM440_RS21870	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM440_RS21875	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AM440_RS21875	COG3261	NADH dehydrogenase
AM440_RS21880	COG0651	ATP synthesis coupled electron transport
AM440_RS21885	COG4237	Hydrogenase 4 membrane
AM440_RS21890	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AM440_RS21895	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AM440_RS21900	COG0650	Formate hydrogenlyase subunit 4
AM440_RS21905	COG0651	ATP synthesis coupled electron transport
AM440_RS21910	COG0651	ATP synthesis coupled electron transport
AM440_RS21915	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM440_RS21920	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AM440_RS21925	COG2716	regulation of RNA biosynthetic process
AM440_RS21935	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AM440_RS21945	COG2321	neutral zinc metallopeptidase
AM440_RS21955	COG0400	carboxylic ester hydrolase activity
AM440_RS21970	COG1393	Belongs to the ArsC family
AM440_RS21980	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM440_RS21985	COG3850	Histidine kinase
AM440_RS21990	COG0493	'glutamate synthase
AM440_RS21990	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM440_RS22000	COG5342	invasion associated locus B
AM440_RS22005	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AM440_RS22010	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM440_RS22020	COG0280	phosphate acetyltransferase
AM440_RS22020	COG0281	malic enzyme
AM440_RS22025	COG4810	utilization protein
AM440_RS22030	COG4917	ethanolamine utilization protein
AM440_RS22035	COG4766	ethanolamine catabolic process
AM440_RS22040	COG4812	Cobalamin adenosyltransferase
AM440_RS22045	COG0280	phosphate acetyltransferase
AM440_RS22050	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AM440_RS22055	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
AM440_RS22060	COG1012	belongs to the aldehyde dehydrogenase family
AM440_RS22065	COG4820	ethanolamine utilization protein (EutJ)
AM440_RS22070	COG1454	alcohol dehydrogenase
AM440_RS22075	COG3192	ethanolamine utilization protein
AM440_RS22080	COG4819	ethanolamine utilization protein
AM440_RS22140	COG0582	viral genome integration into host DNA
AM440_RS22145	COG4303	Ethanolamine ammonia lyase large subunit
AM440_RS22155	COG4816	utilization protein
AM440_RS22160	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AM440_RS22165	COG2207	Transcriptional regulator
AM440_RS22175	COG0860	N-Acetylmuramoyl-L-alanine amidase
AM440_RS22180	COG0456	acetyltransferase
AM440_RS22195	COG2837	iron assimilation
AM440_RS22200	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AM440_RS22205	COG1263	PTS System
AM440_RS22205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM440_RS22220	COG1028	Short-chain dehydrogenase reductase Sdr
AM440_RS22225	COG4150	thiosulfate binding
AM440_RS22230	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AM440_RS22235	COG4208	sulfate ABC transporter
AM440_RS22240	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AM440_RS22245	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AM440_RS22255	COG3831	ATPase activity
AM440_RS22255	COG4884	unkown
AM440_RS22270	COG2190	(PTS) system
AM440_RS22275	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM440_RS22280	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM440_RS22285	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AM440_RS22305	COG3530	Putative quorum-sensing-regulated virulence factor
AM440_RS22310	COG0385	Bile acid
AM440_RS22315	COG0583	DNA-binding transcription factor activity
AM440_RS22325	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AM440_RS22330	COG2211	Major facilitator Superfamily
AM440_RS22340	COG0583	DNA-binding transcription factor activity
AM440_RS22370	COG3415	Transposase
AM440_RS22375	COG3415	Transposase
AM440_RS22395	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AM440_RS22420	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM440_RS22425	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM440_RS22430	COG0006	proline dipeptidase activity
AM440_RS22435	COG1363	Peptidase, m42
AM440_RS22440	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM440_RS22440	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM440_RS22440	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM440_RS22445	COG2207	Transcriptional regulator
AM440_RS22450	COG3279	Response regulator of the LytR AlgR family
AM440_RS22455	COG3275	phosphorelay sensor kinase activity
AM440_RS22460	COG0436	Aminotransferase
AM440_RS22470	COG1560	Kdo2-lipid A biosynthetic process
AM440_RS22495	COG0028	Belongs to the TPP enzyme family
AM440_RS22500	COG0679	Auxin Efflux Carrier
AM440_RS22505	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AM440_RS22510	COG2198	Histidine kinase
AM440_RS22510	COG0784	Response regulator, receiver
AM440_RS22510	COG2205	protein histidine kinase activity
AM440_RS22510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM440_RS22515	COG2197	response regulator
AM440_RS22520	COG1566	PFAM secretion protein HlyD family protein
AM440_RS22525	COG0477	Major facilitator Superfamily
AM440_RS22535	COG2610	gluconate transmembrane transporter activity
AM440_RS22545	COG2963	transposase activity
AM440_RS22550	COG2826	transposase and inactivated derivatives, IS30 family
AM440_RS22555	COG2963	transposase activity
AM440_RS22570	COG2963	transposase activity
AM440_RS22625	COG0582	viral genome integration into host DNA
AM440_RS22635	COG2116	formate transmembrane transporter activity
AM440_RS22645	COG2853	Lipoprotein
AM440_RS22660	COG2067	long-chain fatty acid transport protein
AM440_RS22670	COG3691	Protein conserved in bacteria
AM440_RS22685	COG2062	phosphohistidine phosphatase, SixA
AM440_RS22690	COG3539	Fimbrial protein
AM440_RS22695	COG3188	usher protein
AM440_RS22700	COG3121	Chaperone
AM440_RS22705	COG3539	Fimbrial protein
AM440_RS22710	COG3539	Fimbrial protein
AM440_RS22715	COG3539	Fimbrial protein
AM440_RS22745	COG0730	response to heat
AM440_RS22750	COG3101	peptidyl-lysine hydroxylation
AM440_RS22765	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM440_RS22775	COG2814	Major facilitator Superfamily
AM440_RS22790	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AM440_RS22800	COG0586	Pfam SNARE associated Golgi protein
AM440_RS22810	COG0285	dihydrofolate synthase activity
AM440_RS22815	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AM440_RS22820	COG1286	toxin biosynthetic process
AM440_RS22825	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AM440_RS22830	COG0163	prenyltransferase activity
AM440_RS22835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM440_RS22840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM440_RS22845	COG4215	(ABC) transporter
AM440_RS22850	COG4160	amino acid transport
AM440_RS22855	COG4598	ABC transporter
AM440_RS22865	COG1090	epimerase
AM440_RS22870	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AM440_RS22875	COG0625	glutathione transferase activity
AM440_RS22880	COG0625	glutathione transferase activity
AM440_RS22885	COG0622	Phosphoesterase
AM440_RS22890	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AM440_RS22895	COG1288	antiporter activity
AM440_RS22900	COG0857	belongs to the CobB CobQ family
AM440_RS22900	COG0280	phosphate acetyltransferase
AM440_RS22905	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AM440_RS22920	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM440_RS22925	COG0471	metal ion transport
AM440_RS22925	COG0490	domain, Protein
AM440_RS22935	COG0436	Aminotransferase
AM440_RS22945	COG0583	DNA-binding transcription factor activity
AM440_RS22965	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AM440_RS22970	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AM440_RS22975	COG1034	ATP synthesis coupled electron transport
AM440_RS22990	COG0839	Belongs to the complex I subunit 6 family
AM440_RS23000	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AM440_RS23005	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM440_RS23015	COG0457	Tetratricopeptide repeat
AM440_RS23035	COG2234	aminopeptidase activity
AM440_RS23040	COG2304	oxidoreductase activity
AM440_RS23045	COG5160	protein modification by small protein removal
AM440_RS23055	COG2153	protein acetylation
AM440_RS23060	COG4575	ribosome binding
AM440_RS23065	COG1169	isochorismate synthase
AM440_RS23080	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AM440_RS23090	COG0318	PFAM AMP-dependent synthetase and ligase
AM440_RS23155	COG1414	Transcriptional regulator
AM440_RS23165	COG2271	Major facilitator Superfamily
AM440_RS23175	COG5464	transposase or invertase
AM440_RS23180	COG0247	lactate metabolic process
AM440_RS23190	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AM440_RS23195	COG2271	Major facilitator Superfamily
AM440_RS23200	COG0584	glycerophosphoryl diester phosphodiesterase
AM440_RS23205	COG0583	DNA-binding transcription factor activity
AM440_RS23215	COG3642	lipopolysaccharide core region biosynthetic process
AM440_RS23220	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM440_RS23225	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AM440_RS23230	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AM440_RS23240	COG3468	outer membrane autotransporter barrel domain protein
AM440_RS23250	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AM440_RS23255	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
AM440_RS23260	COG3234	Protein of unknown function (DUF1175)
AM440_RS23270	COG5445	Predicted secreted protein (DUF2300)
AM440_RS23275	COG4676	Protein conserved in bacteria
AM440_RS23280	COG0183	Belongs to the thiolase family
AM440_RS23285	COG2031	fatty acid transporter
AM440_RS23290	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AM440_RS23295	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AM440_RS23300	COG2204	response regulator
AM440_RS23310	COG2205	protein histidine kinase activity
AM440_RS23310	COG0784	Response regulator, receiver
AM440_RS23315	COG2197	response regulator
AM440_RS23320	COG0642	Histidine kinase
AM440_RS23320	COG2198	Histidine kinase
AM440_RS23330	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AM440_RS23335	COG1477	protein flavinylation
AM440_RS23340	COG2169	Transcriptional regulator
AM440_RS23340	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM440_RS23345	COG3145	DNA-N1-methyladenine dioxygenase activity
AM440_RS23350	COG4615	Cyclic peptide transporter
AM440_RS23370	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM440_RS23370	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM440_RS23375	COG3062	negative regulation of establishment of protein localization
AM440_RS23385	COG0437	4 iron, 4 sulfur cluster binding
AM440_RS23390	COG0348	domain, Protein
AM440_RS23395	COG3043	anaerobic respiration
AM440_RS23400	COG3005	denitrification pathway
AM440_RS23405	COG4133	protoheme IX ABC transporter activity
AM440_RS23410	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AM440_RS23415	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AM440_RS23420	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AM440_RS23430	COG1138	Cytochrome C-type biogenesis protein
AM440_RS23435	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AM440_RS23440	COG3088	subunit of a heme lyase
AM440_RS23440	COG4235	cytochrome complex assembly
AM440_RS23445	COG2197	response regulator
AM440_RS23455	COG3468	outer membrane autotransporter barrel domain protein
AM440_RS23465	COG3083	sulfuric ester hydrolase activity
AM440_RS23485	COG1061	Type III restriction enzyme res subunit
AM440_RS23495	COG1187	pseudouridine synthase activity
AM440_RS23500	COG2814	Major facilitator Superfamily
AM440_RS23515	COG4172	Belongs to the ABC transporter superfamily
AM440_RS23520	COG4239	(ABC) transporter, permease
AM440_RS23525	COG4174	ABC transporter (Permease)
AM440_RS23530	COG4166	transmembrane transport
AM440_RS23535	COG2200	EAL domain
AM440_RS23540	COG0791	NLP P60 protein
AM440_RS23665	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
AM440_RS23725	COG4644	lycopene metabolic process
AM440_RS23740	COG2801	Transposase and inactivated derivatives
AM440_RS23750	COG2801	Transposase and inactivated derivatives
AM440_RS23785	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AM440_RS23840	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM440_RS24145	COG0697	spore germination
AM440_RS24220	COG3188	usher protein
AM440_RS24250	COG2207	Transcriptional regulator
AM440_RS24265	COG1192	Involved in chromosome partitioning
AM440_RS24305	COG2026	Addiction module toxin, RelE StbE family
AM440_RS24355	COG4221	oxidoreductase activity
AM440_RS24380	COG5001	Diguanylate cyclase
AM440_RS24380	COG3300	MHYT domain