locus-tag	class	description
AM408_RS00035	COG1595	DNA-templated transcription, initiation
AM408_RS00040	COG3712	iron ion homeostasis
AM408_RS00045	COG4772	TonB-dependent receptor
AM408_RS00050	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AM408_RS00055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM408_RS00060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM408_RS00065	COG1120	ATPase activity
AM408_RS00070	COG2085	NADP oxidoreductase coenzyme F420-dependent
AM408_RS00185	COG4644	lycopene metabolic process
AM408_RS00205	COG0697	spore germination
AM408_RS00220	COG1482	cell wall glycoprotein biosynthetic process
AM408_RS00225	COG4974	Belongs to the 'phage' integrase family
AM408_RS00315	COG2948	multi-organism process
AM408_RS00320	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
AM408_RS00345	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AM408_RS00425	COG2963	transposase activity
AM408_RS00450	COG2801	Transposase and inactivated derivatives
AM408_RS00500	COG2801	Transposase and inactivated derivatives
AM408_RS00555	COG0582	viral genome integration into host DNA
AM408_RS00580	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM408_RS00590	COG3077	Addiction module antitoxin, RelB DinJ family
AM408_RS00595	COG2026	Addiction module toxin, RelE StbE family
AM408_RS00685	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
AM408_RS00790	COG0484	heat shock protein binding
AM408_RS00830	COG1192	Involved in chromosome partitioning
AM408_RS00865	COG1324	tolerance protein
AM408_RS00870	COG0673	inositol 2-dehydrogenase activity
AM408_RS00890	COG3039	Transposase
AM408_RS00900	COG2826	transposase and inactivated derivatives, IS30 family
AM408_RS00915	COG4644	lycopene metabolic process
AM408_RS00975	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AM408_RS00980	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM408_RS01000	COG0058	SHG alpha-glucan phosphorylase activity
AM408_RS01005	COG1640	4-alpha-glucanotransferase
AM408_RS01010	COG2610	gluconate transmembrane transporter activity
AM408_RS01020	COG1040	competence protein
AM408_RS01030	COG5464	transposase or invertase
AM408_RS01045	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AM408_RS01050	COG1918	ferrous iron import across plasma membrane
AM408_RS01060	COG2183	response to ionizing radiation
AM408_RS01065	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AM408_RS01095	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AM408_RS01105	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AM408_RS01110	COG1011	Hydrolase
AM408_RS01120	COG0494	nUDIX hydrolase
AM408_RS01125	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AM408_RS01130	COG4972	Pilus assembly protein
AM408_RS01135	COG3166	PFAM Fimbrial assembly family protein
AM408_RS01150	COG4796	Type ii and iii secretion system protein
AM408_RS01165	COG3266	domain, Protein
AM408_RS01170	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AM408_RS01175	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AM408_RS01180	COG0546	phosphoglycolate phosphatase activity
AM408_RS01185	COG0180	Tryptophanyl-tRNA synthetase
AM408_RS01195	COG2188	Transcriptional regulator
AM408_RS01205	COG3457	Alanine racemase
AM408_RS01210	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AM408_RS01215	COG1735	metal-dependent hydrolase with the TIM-barrel fold
AM408_RS01230	COG0626	cystathionine gamma-synthase activity
AM408_RS01235	COG2188	Transcriptional regulator
AM408_RS01240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM408_RS01245	COG1082	Xylose isomerase domain protein TIM barrel
AM408_RS01250	COG1082	Xylose isomerase domain protein TIM barrel
AM408_RS01255	COG2222	sugar isomerase
AM408_RS01260	COG0531	amino acid
AM408_RS01275	COG2116	formate transmembrane transporter activity
AM408_RS01280	COG2146	nitrite reductase [NAD(P)H] activity
AM408_RS01285	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM408_RS01295	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AM408_RS01305	COG2184	nucleotidyltransferase activity
AM408_RS01310	COG0512	Glutamine amidotransferase of anthranilate synthase
AM408_RS01315	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AM408_RS01320	COG1289	transmembrane transporter activity
AM408_RS01325	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM408_RS01335	COG1765	OsmC-like protein
AM408_RS01340	COG3954	Phosphoribulokinase
AM408_RS01350	COG0429	hydrolase of the alpha beta-hydrolase fold
AM408_RS01355	COG0488	(ABC) transporter
AM408_RS01375	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AM408_RS01380	COG1047	Peptidyl-prolyl cis-trans
AM408_RS01390	COG0545	Peptidyl-prolyl cis-trans isomerase
AM408_RS01395	COG2964	Protein conserved in bacteria
AM408_RS01440	COG3979	chitinase
AM408_RS01445	COG2906	2 iron, 2 sulfur cluster binding
AM408_RS01450	COG2193	ferroxidase activity
AM408_RS01455	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AM408_RS01460	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AM408_RS01465	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AM408_RS01470	COG3156	type II secretion system protein K
AM408_RS01475	COG4795	General secretion pathway protein
AM408_RS01480	COG2165	general secretion pathway protein
AM408_RS01485	COG2165	general secretion pathway protein
AM408_RS01490	COG2165	general secretion pathway protein
AM408_RS01495	COG1459	type II secretion system
AM408_RS01500	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AM408_RS01505	COG1450	Type ii and iii secretion system protein
AM408_RS01510	COG3031	protein transport across the cell outer membrane
AM408_RS01515	COG3409	Peptidoglycan-binding domain 1 protein
AM408_RS01515	COG3267	Type II secretory pathway component ExeA
AM408_RS01545	COG0089	rRNA binding
AM408_RS01635	COG0201	protein transport
AM408_RS01675	COG0789	Transcriptional regulator
AM408_RS01680	COG3036	rescue of stalled ribosome
AM408_RS01690	COG0569	domain protein
AM408_RS01710	COG0758	DNA mediated transformation
AM408_RS01720	COG0551	DNA topoisomerase type I activity
AM408_RS01740	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM408_RS01780	COG1126	abc transporter atp-binding protein
AM408_RS01785	COG0765	amino acid transport
AM408_RS01790	COG4597	amino acid ABC transporter
AM408_RS01795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM408_RS01815	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM408_RS01820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM408_RS01835	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AM408_RS01845	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM408_RS01855	COG4145	pantothenate transmembrane transporter activity
AM408_RS01860	COG3924	membrane
AM408_RS01865	COG0439	Biotin carboxylase
AM408_RS01870	COG0511	ligase activity, forming carbon-carbon bonds
AM408_RS01880	COG0604	alcohol dehydrogenase
AM408_RS01885	COG2200	EAL domain
AM408_RS01885	COG2199	diguanylate cyclase activity
AM408_RS01900	COG1077	Cell shape determining protein MreB Mrl
AM408_RS01905	COG1792	Involved in formation and maintenance of cell shape
AM408_RS01910	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AM408_RS01915	COG0424	maF-like protein
AM408_RS01920	COG1530	ribonuclease E activity
AM408_RS01925	COG3164	Protein of unknown function
AM408_RS01930	COG0312	modulator of DNA gyrase
AM408_RS01935	COG0583	DNA-binding transcription factor activity
AM408_RS01955	COG2732	(Barnase) inhibitor
AM408_RS01975	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM408_RS01980	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM408_RS01985	COG3105	Protein conserved in bacteria
AM408_RS01990	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AM408_RS02010	COG0625	glutathione transferase activity
AM408_RS02015	COG2969	positive regulation of protein catabolic process
AM408_RS02020	COG3069	C4-dicarboxylate transmembrane transporter activity
AM408_RS02055	COG2731	YhcH YjgK YiaL family protein
AM408_RS02060	COG4804	nuclease activity
AM408_RS02080	COG3344	reverse transcriptase
AM408_RS02090	COG4804	nuclease activity
AM408_RS02095	COG3539	Fimbrial protein
AM408_RS02105	COG3188	usher protein
AM408_RS02110	COG3121	Chaperone
AM408_RS02115	COG3539	Fimbrial protein
AM408_RS02125	COG0493	'glutamate synthase
AM408_RS02130	COG0067	glutamate synthase
AM408_RS02130	COG0069	glutamate synthase activity
AM408_RS02130	COG0070	glutamate synthase
AM408_RS02145	COG1242	4 iron, 4 sulfur cluster binding
AM408_RS02150	COG0784	Response regulator, receiver
AM408_RS02150	COG2198	Histidine kinase
AM408_RS02150	COG5002	protein histidine kinase activity
AM408_RS02155	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AM408_RS02165	COG0515	serine threonine protein kinase
AM408_RS02170	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM408_RS02185	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AM408_RS02190	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AM408_RS02195	COG1137	ATPase activity
AM408_RS02200	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AM408_RS02205	COG3117	lipopolysaccharide transmembrane transporter activity
AM408_RS02210	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AM408_RS02215	COG0517	IMP dehydrogenase activity
AM408_RS02215	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AM408_RS02220	COG0530	calcium, potassium:sodium antiporter activity
AM408_RS02225	COG1127	ABC transporter
AM408_RS02230	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AM408_RS02235	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AM408_RS02240	COG2854	intermembrane phospholipid transfer
AM408_RS02245	COG3113	response to antibiotic
AM408_RS02250	COG5007	Belongs to the BolA IbaG family
AM408_RS02260	COG3423	Transcriptional regulator
AM408_RS02265	COG0142	geranyltranstransferase activity
AM408_RS02280	COG0697	spore germination
AM408_RS02290	COG2027	D-alanyl-D-alanine carboxypeptidase
AM408_RS02295	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AM408_RS02300	COG1534	Rna-binding protein
AM408_RS02310	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM408_RS02315	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AM408_RS02325	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AM408_RS02340	COG2194	sulfuric ester hydrolase activity
AM408_RS02360	COG0195	Participates in both transcription termination and antitermination
AM408_RS02395	COG0513	Belongs to the DEAD box helicase family
AM408_RS02400	COG0814	amino acid
AM408_RS02405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM408_RS02410	COG0826	peptidase U32
AM408_RS02415	COG0826	peptidase U32
AM408_RS02420	COG3154	lipid carrier protein
AM408_RS02425	COG3153	acetyltransferase
AM408_RS02440	COG0693	protein deglycase activity
AM408_RS02445	COG0702	epimerase
AM408_RS02450	COG0701	Predicted permease
AM408_RS02455	COG2823	Periplasmic or secreted lipoprotein
AM408_RS02470	COG3107	peptidoglycan biosynthetic process
AM408_RS02475	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AM408_RS02480	COG3539	Fimbrial protein
AM408_RS02485	COG3188	usher protein
AM408_RS02490	COG3121	Chaperone
AM408_RS02495	COG3539	Fimbrial protein
AM408_RS02500	COG0363	glucosamine-6-phosphate deaminase activity
AM408_RS02505	COG3716	PTS system mannose fructose sorbose family IID component
AM408_RS02510	COG3715	PTS system
AM408_RS02525	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM408_RS02535	COG2222	sugar isomerase
AM408_RS02540	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AM408_RS02545	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM408_RS02550	COG3716	PTS system mannose fructose sorbose family IID component
AM408_RS02560	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM408_RS02575	COG1349	DNA-binding transcription factor activity
AM408_RS02585	COG2002	toxin-antitoxin pair type II binding
AM408_RS02590	COG2721	sulfolactate sulfo-lyase activity
AM408_RS02595	COG2271	Major facilitator Superfamily
AM408_RS02605	COG2084	Dehydrogenase
AM408_RS02610	COG1929	Belongs to the glycerate kinase type-1 family
AM408_RS02635	COG0583	DNA-binding transcription factor activity
AM408_RS02640	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AM408_RS02650	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AM408_RS02655	COG1882	Formate acetyltransferase
AM408_RS02660	COG0251	oxidation-reduction process
AM408_RS02665	COG1760	l-serine dehydratase
AM408_RS02670	COG0814	amino acid
AM408_RS02685	COG1741	Belongs to the pirin family
AM408_RS02690	COG0583	DNA-binding transcription factor activity
AM408_RS02700	COG3152	Membrane
AM408_RS02720	COG3152	Membrane
AM408_RS02725	COG0435	Glutathione S-transferase
AM408_RS02730	COG2259	Doxx family
AM408_RS02740	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
AM408_RS02745	COG4575	ribosome binding
AM408_RS02750	COG1422	Protein of unknown function (DUF1090)
AM408_RS02760	COG0586	Pfam SNARE associated Golgi protein
AM408_RS02765	COG2186	Transcriptional regulator
AM408_RS02770	COG2271	Major facilitator Superfamily
AM408_RS02780	COG2721	sulfolactate sulfo-lyase activity
AM408_RS02790	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AM408_RS02795	COG0861	Integral membrane protein TerC family
AM408_RS02800	COG0673	inositol 2-dehydrogenase activity
AM408_RS02805	COG2949	membrane
AM408_RS02810	COG1451	nucleotide metabolic process
AM408_RS02825	COG4680	protein conserved in bacteria
AM408_RS02830	COG5499	transcription regulator containing HTH domain
AM408_RS02835	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM408_RS02835	COG1902	pentaerythritol trinitrate reductase activity
AM408_RS02840	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
AM408_RS02840	COG3408	Glycogen debranching enzyme
AM408_RS02850	COG0531	amino acid
AM408_RS02855	COG2731	YhcH YjgK YiaL family protein
AM408_RS02860	COG3250	beta-galactosidase activity
AM408_RS02865	COG1609	Transcriptional regulator
AM408_RS02875	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM408_RS02890	COG0840	transmembrane signaling receptor activity
AM408_RS02895	COG1695	Transcriptional regulator
AM408_RS02905	COG2375	cellular response to nickel ion
AM408_RS02920	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM408_RS02930	COG0358	DNA primase activity
AM408_RS02935	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AM408_RS02950	COG0471	metal ion transport
AM408_RS02955	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AM408_RS02960	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AM408_RS02970	COG0583	DNA-binding transcription factor activity
AM408_RS02980	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AM408_RS02995	COG4991	sh3 domain protein
AM408_RS03005	COG3025	triphosphatase activity
AM408_RS03025	COG2268	Band 7 protein
AM408_RS03030	COG1585	Membrane protein implicated in regulation of membrane protease activity
AM408_RS03040	COG3539	Fimbrial protein
AM408_RS03045	COG3121	Chaperone
AM408_RS03050	COG3188	usher protein
AM408_RS03060	COG3188	usher protein
AM408_RS03065	COG3539	Fimbrial protein
AM408_RS03070	COG2960	long-chain fatty acid transporting porin activity
AM408_RS03090	COG3384	dioxygenase
AM408_RS03095	COG0754	glutathionylspermidine amidase activity
AM408_RS03110	COG1538	Outer membrane efflux protein
AM408_RS03115	COG0494	nUDIX hydrolase
AM408_RS03120	COG3151	Protein conserved in bacteria
AM408_RS03125	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AM408_RS03130	COG3150	esterase
AM408_RS03135	COG0187	DNA topoisomerase II activity
AM408_RS03140	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AM408_RS03145	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM408_RS03160	COG0642	Histidine kinase
AM408_RS03165	COG0745	RESPONSE REGULATOR receiver
AM408_RS03170	COG3111	PFAM Bacterial OB fold (BOF) protein
AM408_RS03175	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AM408_RS03185	COG2944	sequence-specific DNA binding
AM408_RS03190	COG4166	transmembrane transport
AM408_RS03195	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AM408_RS03200	COG0204	Acyl-transferase
AM408_RS03205	COG2132	Multicopper oxidase
AM408_RS03210	COG1032	radical SAM domain protein
AM408_RS03215	COG4238	major outer membrane lipoprotein
AM408_RS03225	COG0656	L-ascorbic acid biosynthetic process
AM408_RS03230	COG1979	alcohol dehydrogenase
AM408_RS03235	COG2207	Transcriptional regulator
AM408_RS03240	COG0586	Pfam SNARE associated Golgi protein
AM408_RS03245	COG0626	cystathionine gamma-synthase activity
AM408_RS03255	COG0811	peptide transport
AM408_RS03260	COG0848	biopolymer transport protein
AM408_RS03265	COG1028	Short-chain dehydrogenase reductase Sdr
AM408_RS03275	COG0667	Aldo Keto reductase
AM408_RS03300	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AM408_RS03305	COG0437	4 iron, 4 sulfur cluster binding
AM408_RS03310	COG5557	Pfam Polysulphide reductase, NrfD
AM408_RS03315	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AM408_RS03320	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AM408_RS03325	COG1773	rubredoxin
AM408_RS03335	COG0298	carbon dioxide binding
AM408_RS03340	COG0625	glutathione transferase activity
AM408_RS03345	COG0754	glutathionylspermidine amidase activity
AM408_RS03350	COG0306	phosphate transporter
AM408_RS03355	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AM408_RS03360	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AM408_RS03365	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AM408_RS03370	COG2244	polysaccharide biosynthetic process
AM408_RS03380	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AM408_RS03385	COG0795	lipopolysaccharide-transporting ATPase activity
AM408_RS03395	COG0156	8-amino-7-oxononanoate synthase activity
AM408_RS03400	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AM408_RS03410	COG0318	PFAM AMP-dependent synthetase and ligase
AM408_RS03415	COG0456	acetyltransferase
AM408_RS03420	COG2186	Transcriptional regulator
AM408_RS03425	COG0277	FAD linked oxidase domain protein
AM408_RS03430	COG0277	FAD linked oxidase domain protein
AM408_RS03435	COG0247	lactate metabolic process
AM408_RS03440	COG3193	protein, possibly involved in utilization of glycolate and propanediol
AM408_RS03445	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AM408_RS03450	COG1620	l-lactate permease
AM408_RS03460	COG3064	Membrane
AM408_RS03465	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AM408_RS03475	COG3031	protein transport across the cell outer membrane
AM408_RS03485	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AM408_RS03490	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AM408_RS03495	COG1459	type II secretion system
AM408_RS03500	COG2165	general secretion pathway protein
AM408_RS03530	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AM408_RS03570	COG2003	Belongs to the UPF0758 family
AM408_RS03595	COG2378	regulation of single-species biofilm formation
AM408_RS03600	COG3596	GTP binding
AM408_RS03635	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AM408_RS03640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM408_RS03645	COG2313	pseudouridylate synthase activity
AM408_RS03650	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AM408_RS03655	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM408_RS03655	COG1522	sequence-specific DNA binding
AM408_RS03710	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AM408_RS03715	COG2207	Transcriptional regulator
AM408_RS03720	COG2972	Histidine kinase
AM408_RS03730	COG3344	reverse transcriptase
AM408_RS03750	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM408_RS03755	COG1882	Formate acetyltransferase
AM408_RS03760	COG0693	protein deglycase activity
AM408_RS03770	COG1012	belongs to the aldehyde dehydrogenase family
AM408_RS03805	COG4820	ethanolamine utilization protein (EutJ)
AM408_RS03810	COG4869	propanediol catabolic process
AM408_RS03870	COG3969	phosphoadenosine phosphosulfate
AM408_RS03875	COG1475	DNA binding
AM408_RS03895	COG1201	RNA secondary structure unwinding
AM408_RS03920	COG2194	sulfuric ester hydrolase activity
AM408_RS03925	COG0582	viral genome integration into host DNA
AM408_RS03935	COG1811	Na channel or pump
AM408_RS03945	COG1982	Orn Lys Arg decarboxylase major
AM408_RS03950	COG2211	Major facilitator Superfamily
AM408_RS03965	COG1194	a g-specific adenine glycosylase
AM408_RS03980	COG3171	Protein conserved in bacteria
AM408_RS03990	COG0252	asparaginase activity
AM408_RS04000	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AM408_RS04005	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AM408_RS04015	COG0762	integral membrane protein
AM408_RS04020	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AM408_RS04025	COG2805	Type II/IV secretion system protein
AM408_RS04040	COG0189	ligase activity
AM408_RS04045	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AM408_RS04050	COG2356	endonuclease I
AM408_RS04060	COG2814	Major facilitator Superfamily
AM408_RS04085	COG1166	arginine decarboxylase activity
AM408_RS04095	COG0501	Belongs to the peptidase M48B family
AM408_RS04100	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AM408_RS04105	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM408_RS04110	COG2213	PTS system mannitol-specific
AM408_RS04115	COG1063	alcohol dehydrogenase
AM408_RS04120	COG1494	fructose-1,6-bisphosphatase
AM408_RS04125	COG3722	fumarate hydratase activity
AM408_RS04130	COG1072	(Pantothenic acid kinase))
AM408_RS04150	COG0191	fructose-bisphosphate aldolase activity
AM408_RS04155	COG0668	transmembrane transport
AM408_RS04160	COG1279	arginine transmembrane transporter activity
AM408_RS04165	COG2968	Membrane
AM408_RS04170	COG0583	DNA-binding transcription factor activity
AM408_RS04175	COG0427	acetyl-CoA hydrolase
AM408_RS04180	COG1024	Enoyl-CoA hydratase
AM408_RS04185	COG1703	isobutyryl-CoA mutase activity
AM408_RS04190	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AM408_RS04190	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AM408_RS04215	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM408_RS04230	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AM408_RS04255	COG0006	proline dipeptidase activity
AM408_RS04260	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM408_RS04265	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM408_RS04285	COG1028	Short-chain dehydrogenase reductase Sdr
AM408_RS04290	COG2723	6-phospho-beta-galactosidase activity
AM408_RS04300	COG1272	protein, Hemolysin III
AM408_RS04310	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AM408_RS04320	COG0716	FMN binding
AM408_RS04325	COG4974	Belongs to the 'phage' integrase family
AM408_RS04330	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM408_RS04335	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AM408_RS04345	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AM408_RS04360	COG2233	PERMEase
AM408_RS04370	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM408_RS04370	COG0493	'glutamate synthase
AM408_RS04375	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM408_RS04380	COG2252	PERMEase
AM408_RS04385	COG0402	S-adenosylhomocysteine deaminase activity
AM408_RS04390	COG2233	PERMEase
AM408_RS04395	COG2080	2 iron, 2 sulfur cluster binding
AM408_RS04395	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AM408_RS04400	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AM408_RS04405	COG0402	S-adenosylhomocysteine deaminase activity
AM408_RS04410	COG0493	'glutamate synthase
AM408_RS04410	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM408_RS04415	COG2068	MobA-Related Protein
AM408_RS04420	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AM408_RS04425	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AM408_RS04425	COG3608	succinylglutamate desuccinylase aspartoacylase
AM408_RS04430	COG0549	Belongs to the carbamate kinase family
AM408_RS04440	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AM408_RS04445	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AM408_RS04450	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AM408_RS04455	COG3829	transcription factor binding
AM408_RS04460	COG2080	2 iron, 2 sulfur cluster binding
AM408_RS04465	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AM408_RS04470	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AM408_RS04480	COG4942	peptidase
AM408_RS04490	COG4974	Belongs to the 'phage' integrase family
AM408_RS04500	COG1484	DNA-dependent DNA replication
AM408_RS04505	COG4584	PFAM Integrase catalytic
AM408_RS04530	COG3387	PFAM Glycoside hydrolase 15-related
AM408_RS04535	COG3385	transposase activity
AM408_RS04540	COG3387	PFAM Glycoside hydrolase 15-related
AM408_RS04620	COG2197	response regulator
AM408_RS04625	COG2197	response regulator
AM408_RS04645	COG3710	Transcriptional regulator
AM408_RS04645	COG0457	Tetratricopeptide repeat
AM408_RS04655	COG0457	Tetratricopeptide repeat
AM408_RS04685	COG3710	Transcriptional regulator
AM408_RS04690	COG2771	luxR family
AM408_RS04695	COG0814	amino acid
AM408_RS04700	COG0183	Belongs to the thiolase family
AM408_RS04710	COG1028	Short-chain dehydrogenase reductase Sdr
AM408_RS04715	COG2814	Major facilitator Superfamily
AM408_RS04720	COG1794	racemase activity, acting on amino acids and derivatives
AM408_RS04725	COG0583	DNA-binding transcription factor activity
AM408_RS04735	COG1609	Transcriptional regulator
AM408_RS04750	COG0667	Aldo Keto reductase
AM408_RS04760	COG0861	Integral membrane protein TerC family
AM408_RS04775	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
AM408_RS04790	COG2165	general secretion pathway protein
AM408_RS04795	COG4795	General secretion pathway protein
AM408_RS04805	COG4967	type IV pilus modification protein PilV
AM408_RS04810	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AM408_RS04815	COG1025	Belongs to the peptidase M16 family
AM408_RS04820	COG1074	ATP-dependent DNA helicase activity
AM408_RS04825	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AM408_RS04830	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AM408_RS04830	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AM408_RS04835	COG0860	N-Acetylmuramoyl-L-alanine amidase
AM408_RS04860	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AM408_RS04865	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AM408_RS04870	COG2166	iron-sulfur cluster assembly
AM408_RS04875	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AM408_RS04885	COG0583	DNA-binding transcription factor activity
AM408_RS04890	COG2363	Small membrane protein
AM408_RS04900	COG1349	DNA-binding transcription factor activity
AM408_RS04910	COG1070	Carbohydrate kinase
AM408_RS04920	COG0738	Major facilitator superfamily
AM408_RS04925	COG0235	Class ii aldolase
AM408_RS04930	COG1454	alcohol dehydrogenase
AM408_RS04940	COG1760	l-serine dehydratase
AM408_RS04945	COG0814	amino acid
AM408_RS04950	COG1611	Belongs to the LOG family
AM408_RS04965	COG3098	single-species biofilm formation
AM408_RS04970	COG0564	pseudouridine synthase activity
AM408_RS04975	COG0716	FMN binding
AM408_RS04980	COG2271	Major facilitator Superfamily
AM408_RS04985	COG4948	Mandelate Racemase Muconate Lactonizing
AM408_RS04990	COG4948	Mandelate Racemase Muconate Lactonizing
AM408_RS04995	COG4999	Histidine kinase
AM408_RS04995	COG3850	Histidine kinase
AM408_RS04995	COG3437	response regulator, receiver
AM408_RS04995	COG2205	protein histidine kinase activity
AM408_RS05000	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AM408_RS05005	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM408_RS05010	COG2336	PFAM SpoVT AbrB
AM408_RS05015	COG2337	Toxic component of a toxin-antitoxin (TA) module
AM408_RS05020	COG3956	TIGRFAM MazG family protein
AM408_RS05035	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AM408_RS05045	COG0602	queuosine metabolic process
AM408_RS05050	COG1070	Carbohydrate kinase
AM408_RS05055	COG2223	nitrite transmembrane transporter activity
AM408_RS05060	COG1028	Short-chain dehydrogenase reductase Sdr
AM408_RS05065	COG0277	FAD linked oxidase domain protein
AM408_RS05070	COG0477	Major facilitator Superfamily
AM408_RS05075	COG2086	electron transfer activity
AM408_RS05080	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AM408_RS05085	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AM408_RS05090	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AM408_RS05095	COG0644	oxidoreductase
AM408_RS05100	COG0720	synthase
AM408_RS05120	COG1203	CRISPR-associated helicase, Cas3
AM408_RS05135	COG1857	crispr-associated protein
AM408_RS05150	COG1518	maintenance of DNA repeat elements
AM408_RS05155	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM408_RS05160	COG2234	aminopeptidase activity
AM408_RS05215	COG4942	peptidase
AM408_RS05215	COG1388	LysM domain
AM408_RS05220	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM408_RS05225	COG2610	gluconate transmembrane transporter activity
AM408_RS05230	COG3622	Belongs to the hyi family
AM408_RS05235	COG0235	Class ii aldolase
AM408_RS05240	COG3395	kinase activity
AM408_RS05245	COG2084	Dehydrogenase
AM408_RS05250	COG1349	DNA-binding transcription factor activity
AM408_RS05255	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AM408_RS05270	COG3604	Transcriptional regulator
AM408_RS05275	COG0309	Hydrogenase expression formation protein (HypE)
AM408_RS05280	COG0409	Hydrogenase expression formation protein
AM408_RS05285	COG0298	carbon dioxide binding
AM408_RS05290	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AM408_RS05295	COG0375	protein maturation
AM408_RS05310	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM408_RS05315	COG0651	ATP synthesis coupled electron transport
AM408_RS05320	COG0650	Formate hydrogenlyase subunit 4
AM408_RS05325	COG3261	NADH dehydrogenase
AM408_RS05325	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AM408_RS05330	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM408_RS05335	COG3260	NADH ubiquinone oxidoreductase 20
AM408_RS05345	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AM408_RS05350	COG2723	6-phospho-beta-galactosidase activity
AM408_RS05355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM408_RS05355	COG1263	PTS System
AM408_RS05360	COG1609	Transcriptional regulator
AM408_RS05365	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM408_RS05370	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AM408_RS05390	COG0517	IMP dehydrogenase activity
AM408_RS05390	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AM408_RS05395	COG1349	DNA-binding transcription factor activity
AM408_RS05400	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM408_RS05405	COG1028	Short-chain dehydrogenase reductase Sdr
AM408_RS05410	COG3731	PTS system glucitol sorbitol-specific IIA component
AM408_RS05415	COG3732	PTS system glucitol sorbitol-specific
AM408_RS05420	COG3730	PTS system glucitol sorbitol-specific
AM408_RS05425	COG2951	lytic endotransglycosylase activity
AM408_RS05430	COG1546	Belongs to the CinA family
AM408_RS05450	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AM408_RS05480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM408_RS05485	COG1238	metal cluster binding
AM408_RS05500	COG2814	Major facilitator Superfamily
AM408_RS05505	COG1566	PFAM secretion protein HlyD family protein
AM408_RS05510	COG1846	Transcriptional regulator
AM408_RS05520	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AM408_RS05525	COG2814	Major facilitator Superfamily
AM408_RS05530	COG2113	Glycine betaine
AM408_RS05535	COG4176	ABC-type proline glycine betaine transport system permease component
AM408_RS05540	COG4175	Glycine betaine
AM408_RS05550	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AM408_RS05555	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AM408_RS05565	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM408_RS05570	COG4575	ribosome binding
AM408_RS05585	COG2916	Histone family protein nucleoid-structuring protein H-NS
AM408_RS05590	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AM408_RS05595	COG0640	Transcriptional regulator
AM408_RS05600	COG0401	homolog of Blt101
AM408_RS05605	COG1652	LysM domain
AM408_RS05610	COG1802	Transcriptional regulator
AM408_RS05615	COG1113	amino acid transport
AM408_RS05620	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AM408_RS05625	COG1012	belongs to the aldehyde dehydrogenase family
AM408_RS05630	COG0579	oxidoreductase
AM408_RS05650	COG0366	Alpha amylase catalytic
AM408_RS05705	COG2867	negative regulation of translational initiation
AM408_RS05715	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM408_RS05720	COG0497	DNA recombination
AM408_RS05740	COG4536	flavin adenine dinucleotide binding
AM408_RS05745	COG4137	Cytochrome C assembly protein
AM408_RS05750	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AM408_RS05775	COG2885	chlorophyll binding
AM408_RS05780	COG2199	diguanylate cyclase activity
AM408_RS05795	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM408_RS05800	COG0287	Prephenate dehydrogenase
AM408_RS05800	COG1605	Chorismate mutase
AM408_RS05805	COG0077	Prephenate dehydratase
AM408_RS05805	COG1605	Chorismate mutase
AM408_RS05810	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AM408_RS05820	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM408_RS05825	COG0564	pseudouridine synthase activity
AM408_RS05830	COG1496	oxidoreductase activity
AM408_RS05835	COG0542	response to heat
AM408_RS05865	COG0477	Major facilitator Superfamily
AM408_RS05870	COG5544	Lipoprotein
AM408_RS05875	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM408_RS05880	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM408_RS05880	COG1042	CoA-binding domain protein
AM408_RS05880	COG0045	succinate-CoA ligase (ADP-forming) activity
AM408_RS05885	COG3148	PFAM DTW domain containing protein
AM408_RS05890	COG3118	belongs to the thioredoxin family
AM408_RS05900	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM408_RS05920	COG0583	DNA-binding transcription factor activity
AM408_RS05925	COG0513	Belongs to the DEAD box helicase family
AM408_RS05935	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AM408_RS05940	COG1595	DNA-templated transcription, initiation
AM408_RS05945	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
AM408_RS05950	COG3026	antisigma factor binding
AM408_RS05955	COG3086	response to oxidative stress
AM408_RS05965	COG0681	Belongs to the peptidase S26 family
AM408_RS05990	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AM408_RS06015	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM408_RS06020	COG1737	Transcriptional regulator
AM408_RS06025	COG0560	Phosphoserine phosphatase
AM408_RS06045	COG0047	phosphoribosylformylglycinamidine synthase activity
AM408_RS06045	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AM408_RS06050	COG2205	protein histidine kinase activity
AM408_RS06055	COG3170	Tfp pilus assembly protein FimV
AM408_RS06060	COG2204	response regulator
AM408_RS06065	COG0347	Belongs to the P(II) protein family
AM408_RS06070	COG1017	nitric oxide dioxygenase activity
AM408_RS06070	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM408_RS06080	COG1940	carbohydrate kinase activity
AM408_RS06085	COG0457	Tetratricopeptide repeat
AM408_RS06090	COG1879	ABC-type sugar transport system periplasmic component
AM408_RS06095	COG1129	ABC transporter
AM408_RS06100	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM408_RS06105	COG1063	alcohol dehydrogenase
AM408_RS06110	COG2017	converts alpha-aldose to the beta-anomer
AM408_RS06115	COG2259	Doxx family
AM408_RS06140	COG4638	Rieske (2fe-2S)
AM408_RS06145	COG0583	DNA-binding transcription factor activity
AM408_RS06150	COG2814	Major facilitator Superfamily
AM408_RS06155	COG3711	transcriptional antiterminator
AM408_RS06160	COG1073	alpha beta
AM408_RS06165	COG0483	inositol monophosphate 1-phosphatase activity
AM408_RS06185	COG0822	iron-sulfur transferase activity
AM408_RS06205	COG0633	Ferredoxin
AM408_RS06210	COG2975	iron-sulfur cluster assembly
AM408_RS06225	COG2897	thiosulfate sulfurtransferase activity
AM408_RS06230	COG2373	Large extracellular alpha-helical protein
AM408_RS06235	COG4953	penicillin-binding protein 1C
AM408_RS06265	COG2976	Protein conserved in bacteria
AM408_RS06280	COG1645	bacterial-type flagellum-dependent swarming motility
AM408_RS06290	COG0516	GMP reductase activity
AM408_RS06290	COG0517	IMP dehydrogenase activity
AM408_RS06305	COG3133	Outer membrane lipoprotein
AM408_RS06325	COG2200	EAL domain
AM408_RS06330	COG0248	Ppx GppA phosphatase
AM408_RS06335	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AM408_RS06340	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AM408_RS06360	COG2233	PERMEase
AM408_RS06370	COG1393	Belongs to the ArsC family
AM408_RS06375	COG4783	chaperone-mediated protein folding
AM408_RS06380	COG0628	permease
AM408_RS06385	COG2116	formate transmembrane transporter activity
AM408_RS06390	COG3604	Transcriptional regulator
AM408_RS06400	COG3260	NADH ubiquinone oxidoreductase 20
AM408_RS06405	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM408_RS06410	COG3261	NADH dehydrogenase
AM408_RS06410	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AM408_RS06415	COG0651	ATP synthesis coupled electron transport
AM408_RS06420	COG4237	Hydrogenase 4 membrane
AM408_RS06425	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AM408_RS06430	COG0650	Formate hydrogenlyase subunit 4
AM408_RS06435	COG0651	ATP synthesis coupled electron transport
AM408_RS06440	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM408_RS06445	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AM408_RS06450	COG2716	regulation of RNA biosynthetic process
AM408_RS06460	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AM408_RS06470	COG2321	neutral zinc metallopeptidase
AM408_RS06475	COG1444	tRNA N-acetyltransferase activity
AM408_RS06480	COG0400	carboxylic ester hydrolase activity
AM408_RS06495	COG1393	Belongs to the ArsC family
AM408_RS06505	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM408_RS06510	COG3850	Histidine kinase
AM408_RS06515	COG0493	'glutamate synthase
AM408_RS06515	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM408_RS06525	COG5342	invasion associated locus B
AM408_RS06530	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AM408_RS06535	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM408_RS06545	COG0281	malic enzyme
AM408_RS06545	COG0280	phosphate acetyltransferase
AM408_RS06550	COG4810	utilization protein
AM408_RS06555	COG4917	ethanolamine utilization protein
AM408_RS06560	COG4766	ethanolamine catabolic process
AM408_RS06565	COG4812	Cobalamin adenosyltransferase
AM408_RS06570	COG0280	phosphate acetyltransferase
AM408_RS06575	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AM408_RS06580	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
AM408_RS06585	COG1012	belongs to the aldehyde dehydrogenase family
AM408_RS06590	COG4820	ethanolamine utilization protein (EutJ)
AM408_RS06595	COG1454	alcohol dehydrogenase
AM408_RS06600	COG3192	ethanolamine utilization protein
AM408_RS06605	COG4819	ethanolamine utilization protein
AM408_RS06610	COG4303	Ethanolamine ammonia lyase large subunit
AM408_RS06620	COG4816	utilization protein
AM408_RS06625	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AM408_RS06630	COG2207	Transcriptional regulator
AM408_RS06640	COG0860	N-Acetylmuramoyl-L-alanine amidase
AM408_RS06645	COG0456	acetyltransferase
AM408_RS06660	COG2837	iron assimilation
AM408_RS06665	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AM408_RS06670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM408_RS06670	COG1263	PTS System
AM408_RS06685	COG1028	Short-chain dehydrogenase reductase Sdr
AM408_RS06695	COG4150	thiosulfate binding
AM408_RS06700	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AM408_RS06705	COG4208	sulfate ABC transporter
AM408_RS06710	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AM408_RS06715	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AM408_RS06720	COG3831	ATPase activity
AM408_RS06720	COG4884	unkown
AM408_RS06735	COG2190	(PTS) system
AM408_RS06740	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM408_RS06745	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM408_RS06750	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AM408_RS06770	COG3530	Putative quorum-sensing-regulated virulence factor
AM408_RS06775	COG0385	Bile acid
AM408_RS06780	COG0583	DNA-binding transcription factor activity
AM408_RS06790	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AM408_RS06795	COG2211	Major facilitator Superfamily
AM408_RS06805	COG0583	DNA-binding transcription factor activity
AM408_RS06835	COG3415	Transposase
AM408_RS06840	COG3415	Transposase
AM408_RS06855	COG2200	EAL domain
AM408_RS06855	COG2199	diguanylate cyclase activity
AM408_RS06860	COG3385	transposase activity
AM408_RS06865	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AM408_RS06890	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM408_RS06895	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM408_RS06900	COG0006	proline dipeptidase activity
AM408_RS06905	COG1363	Peptidase, m42
AM408_RS06910	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM408_RS06910	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM408_RS06910	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM408_RS06920	COG3279	Response regulator of the LytR AlgR family
AM408_RS06925	COG3275	phosphorelay sensor kinase activity
AM408_RS06930	COG0436	Aminotransferase
AM408_RS06940	COG1560	Kdo2-lipid A biosynthetic process
AM408_RS06965	COG0028	Belongs to the TPP enzyme family
AM408_RS06970	COG0679	Auxin Efflux Carrier
AM408_RS06975	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AM408_RS06980	COG0784	Response regulator, receiver
AM408_RS06980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM408_RS06980	COG2198	Histidine kinase
AM408_RS06980	COG2205	protein histidine kinase activity
AM408_RS06985	COG2197	response regulator
AM408_RS06990	COG1566	PFAM secretion protein HlyD family protein
AM408_RS06995	COG0477	Major facilitator Superfamily
AM408_RS07005	COG2610	gluconate transmembrane transporter activity
AM408_RS07035	COG2116	formate transmembrane transporter activity
AM408_RS07045	COG2853	Lipoprotein
AM408_RS07060	COG3547	Transposase (IS116 IS110 IS902 family)
AM408_RS07065	COG2067	long-chain fatty acid transport protein
AM408_RS07075	COG3691	Protein conserved in bacteria
AM408_RS07090	COG2062	phosphohistidine phosphatase, SixA
AM408_RS07095	COG3539	Fimbrial protein
AM408_RS07100	COG3188	usher protein
AM408_RS07105	COG3121	Chaperone
AM408_RS07110	COG3539	Fimbrial protein
AM408_RS07115	COG3539	Fimbrial protein
AM408_RS07120	COG3539	Fimbrial protein
AM408_RS07135	COG2890	protein-(glutamine-N5) methyltransferase activity
AM408_RS07150	COG0730	response to heat
AM408_RS07155	COG3101	peptidyl-lysine hydroxylation
AM408_RS07170	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM408_RS07180	COG2814	Major facilitator Superfamily
AM408_RS07195	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AM408_RS07205	COG0586	Pfam SNARE associated Golgi protein
AM408_RS07215	COG0285	dihydrofolate synthase activity
AM408_RS07220	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AM408_RS07225	COG1286	toxin biosynthetic process
AM408_RS07230	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AM408_RS07235	COG0163	prenyltransferase activity
AM408_RS07240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM408_RS07245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM408_RS07250	COG4215	(ABC) transporter
AM408_RS07255	COG4160	amino acid transport
AM408_RS07260	COG4598	ABC transporter
AM408_RS07265	COG5464	transposase or invertase
AM408_RS07270	COG1090	epimerase
AM408_RS07275	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AM408_RS07280	COG0625	glutathione transferase activity
AM408_RS07285	COG0625	glutathione transferase activity
AM408_RS07290	COG0622	Phosphoesterase
AM408_RS07295	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AM408_RS07300	COG1288	antiporter activity
AM408_RS07305	COG0857	belongs to the CobB CobQ family
AM408_RS07305	COG0280	phosphate acetyltransferase
AM408_RS07310	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AM408_RS07325	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM408_RS07330	COG0490	domain, Protein
AM408_RS07330	COG0471	metal ion transport
AM408_RS07340	COG0436	Aminotransferase
AM408_RS07350	COG0583	DNA-binding transcription factor activity
AM408_RS07370	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AM408_RS07375	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AM408_RS07380	COG1034	ATP synthesis coupled electron transport
AM408_RS07395	COG0839	Belongs to the complex I subunit 6 family
AM408_RS07405	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AM408_RS07410	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM408_RS07420	COG0457	Tetratricopeptide repeat
AM408_RS07440	COG2234	aminopeptidase activity
AM408_RS07445	COG2304	oxidoreductase activity
AM408_RS07450	COG5160	protein modification by small protein removal
AM408_RS07460	COG2153	protein acetylation
AM408_RS07465	COG4575	ribosome binding
AM408_RS07470	COG1169	isochorismate synthase
AM408_RS07485	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AM408_RS07495	COG0318	PFAM AMP-dependent synthetase and ligase
AM408_RS07560	COG1414	Transcriptional regulator
AM408_RS07565	COG1414	Transcriptional regulator
AM408_RS07575	COG2271	Major facilitator Superfamily
AM408_RS07590	COG5464	transposase or invertase
AM408_RS07595	COG0247	lactate metabolic process
AM408_RS07605	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AM408_RS07610	COG2271	Major facilitator Superfamily
AM408_RS07615	COG0584	glycerophosphoryl diester phosphodiesterase
AM408_RS07620	COG0583	DNA-binding transcription factor activity
AM408_RS07630	COG3642	lipopolysaccharide core region biosynthetic process
AM408_RS07635	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM408_RS07640	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AM408_RS07645	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AM408_RS07655	COG3468	outer membrane autotransporter barrel domain protein
AM408_RS07665	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AM408_RS07670	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
AM408_RS07675	COG3234	Protein of unknown function (DUF1175)
AM408_RS07680	COG2373	Large extracellular alpha-helical protein
AM408_RS07685	COG5445	Predicted secreted protein (DUF2300)
AM408_RS07690	COG4676	Protein conserved in bacteria
AM408_RS07695	COG0183	Belongs to the thiolase family
AM408_RS07700	COG2031	fatty acid transporter
AM408_RS07705	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AM408_RS07710	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AM408_RS07715	COG2204	response regulator
AM408_RS07720	COG3852	Histidine kinase
AM408_RS07725	COG0784	Response regulator, receiver
AM408_RS07725	COG2205	protein histidine kinase activity
AM408_RS07730	COG2197	response regulator
AM408_RS07735	COG2198	Histidine kinase
AM408_RS07735	COG0642	Histidine kinase
AM408_RS07750	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AM408_RS07755	COG1477	protein flavinylation
AM408_RS07760	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM408_RS07760	COG2169	Transcriptional regulator
AM408_RS07765	COG3145	DNA-N1-methyladenine dioxygenase activity
AM408_RS07770	COG4615	Cyclic peptide transporter
AM408_RS07790	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM408_RS07790	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM408_RS07795	COG3062	negative regulation of establishment of protein localization
AM408_RS07805	COG0437	4 iron, 4 sulfur cluster binding
AM408_RS07810	COG0348	domain, Protein
AM408_RS07815	COG3043	anaerobic respiration
AM408_RS07820	COG3005	denitrification pathway
AM408_RS07825	COG4133	protoheme IX ABC transporter activity
AM408_RS07830	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AM408_RS07835	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AM408_RS07840	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AM408_RS07850	COG1138	Cytochrome C-type biogenesis protein
AM408_RS07855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AM408_RS07860	COG4235	cytochrome complex assembly
AM408_RS07860	COG3088	subunit of a heme lyase
AM408_RS07865	COG2197	response regulator
AM408_RS07875	COG3468	outer membrane autotransporter barrel domain protein
AM408_RS07885	COG3083	sulfuric ester hydrolase activity
AM408_RS07905	COG1061	Type III restriction enzyme res subunit
AM408_RS07915	COG1187	pseudouridine synthase activity
AM408_RS07920	COG2814	Major facilitator Superfamily
AM408_RS07935	COG4172	Belongs to the ABC transporter superfamily
AM408_RS07940	COG4239	(ABC) transporter, permease
AM408_RS07945	COG4174	ABC transporter (Permease)
AM408_RS07950	COG4166	transmembrane transport
AM408_RS07955	COG2200	EAL domain
AM408_RS07960	COG0791	NLP P60 protein
AM408_RS07965	COG0671	phosphoesterase, PA-phosphatase related
AM408_RS07970	COG0523	cobalamin synthesis protein
AM408_RS07975	COG0246	Mannitol dehydrogenase
AM408_RS07990	COG2814	Major facilitator Superfamily
AM408_RS07995	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM408_RS07995	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM408_RS08000	COG1105	Belongs to the carbohydrate kinase PfkB family
AM408_RS08005	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM408_RS08005	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AM408_RS08005	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM408_RS08010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM408_RS08015	COG2313	pseudouridylate synthase activity
AM408_RS08020	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AM408_RS08025	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM408_RS08035	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AM408_RS08040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM408_RS08040	COG1522	sequence-specific DNA binding
AM408_RS08050	COG2855	membrane
AM408_RS08055	COG0583	DNA-binding transcription factor activity
AM408_RS08065	COG0833	amino acid
AM408_RS08100	COG2311	Membrane
AM408_RS08110	COG1609	Transcriptional regulator
AM408_RS08115	COG1879	ABC-type sugar transport system periplasmic component
AM408_RS08120	COG1129	ABC transporter
AM408_RS08125	COG4211	Belongs to the binding-protein-dependent transport system permease family
AM408_RS08130	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AM408_RS08130	COG0167	dihydroorotate dehydrogenase activity
AM408_RS08135	COG0493	'glutamate synthase
AM408_RS08150	COG2949	membrane
AM408_RS08160	COG1346	cytolysis
AM408_RS08170	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM408_RS08195	COG1028	Short-chain dehydrogenase reductase Sdr
AM408_RS08200	COG0586	Pfam SNARE associated Golgi protein
AM408_RS08210	COG1686	Belongs to the peptidase S11 family
AM408_RS08215	COG0277	FAD linked oxidase domain protein
AM408_RS08220	COG1472	Belongs to the glycosyl hydrolase 3 family
AM408_RS08225	COG1732	Glycine betaine
AM408_RS08230	COG1174	glycine betaine transport
AM408_RS08235	COG1125	glycine betaine transport
AM408_RS08240	COG1174	glycine betaine transport
AM408_RS08250	COG0789	Transcriptional regulator
AM408_RS08255	COG3275	phosphorelay sensor kinase activity
AM408_RS08260	COG3279	Response regulator of the LytR AlgR family
AM408_RS08265	COG4807	Protein conserved in bacteria
AM408_RS08270	COG4808	Protein conserved in bacteria
AM408_RS08275	COG4715	Zinc finger, swim domain protein
AM408_RS08280	COG3552	Protein containing von Willebrand factor type A (VWA) domain
AM408_RS08300	COG3831	ATPase activity
AM408_RS08305	COG3831	ATPase activity
AM408_RS08310	COG3831	ATPase activity
AM408_RS08320	COG0489	protein tyrosine kinase activity
AM408_RS08335	COG3539	Fimbrial protein
AM408_RS08340	COG3121	Chaperone
AM408_RS08345	COG3188	usher protein
AM408_RS08350	COG3539	Fimbrial protein
AM408_RS08355	COG5455	response to cobalt ion
AM408_RS08375	COG0351	phosphomethylpyrimidine kinase
AM408_RS08380	COG3757	hydrolase, family 25
AM408_RS08385	COG2188	Transcriptional regulator
AM408_RS08390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM408_RS08395	COG1397	ADP-ribosylglycohydrolase
AM408_RS08400	COG2211	Major facilitator Superfamily
AM408_RS08405	COG1830	Aldolase
AM408_RS08420	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM408_RS08425	COG3414	Phosphotransferase system galactitol-specific IIB component
AM408_RS08430	COG3775	system Galactitol-specific IIC component
AM408_RS08435	COG1063	alcohol dehydrogenase
AM408_RS08460	COG0826	peptidase U32
AM408_RS08470	COG3609	addiction module antidote protein, CC2985 family
AM408_RS08480	COG0745	RESPONSE REGULATOR receiver
AM408_RS08485	COG2205	protein histidine kinase activity
AM408_RS08515	COG4245	von Willebrand factor, type A
AM408_RS08520	COG0631	protein serine/threonine phosphatase activity
AM408_RS08530	COG0443	Heat shock 70 kDa protein
AM408_RS08535	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AM408_RS08545	COG0572	uridine kinase
AM408_RS08555	COG2982	Protein involved in outer membrane biogenesis
AM408_RS08560	COG1253	flavin adenine dinucleotide binding
AM408_RS08615	COG0463	Glycosyl transferase, family 2
AM408_RS08645	COG1088	dTDP-glucose 4,6-dehydratase activity
AM408_RS08685	COG0140	phosphoribosyl-ATP diphosphatase activity
AM408_RS08685	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AM408_RS08700	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AM408_RS08705	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AM408_RS08705	COG0131	Imidazoleglycerol-phosphate dehydratase
AM408_RS08735	COG2161	toxin-antitoxin pair type II binding
AM408_RS08740	COG4115	mRNA cleavage
AM408_RS08745	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM408_RS08750	COG0583	DNA-binding transcription factor activity
AM408_RS08755	COG0531	amino acid
AM408_RS08760	COG2391	methyltransferase activity
AM408_RS08765	COG0425	Belongs to the sulfur carrier protein TusA family
AM408_RS08770	COG2925	Exonuclease
AM408_RS08785	COG1289	transmembrane transporter activity
AM408_RS08795	COG4917	ethanolamine utilization protein
AM408_RS08830	COG2003	Belongs to the UPF0758 family
AM408_RS08835	COG4584	PFAM Integrase catalytic
AM408_RS08840	COG1484	DNA-dependent DNA replication
AM408_RS08960	COG1735	metal-dependent hydrolase with the TIM-barrel fold
AM408_RS08975	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
AM408_RS08990	COG1376	ErfK ybiS ycfS ynhG family protein
AM408_RS09000	COG0583	DNA-binding transcription factor activity
AM408_RS09005	COG0583	DNA-binding transcription factor activity
AM408_RS09015	COG0534	Mate efflux family protein
AM408_RS09030	COG0217	transcriptional regulatory protein
AM408_RS09035	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AM408_RS09040	COG0477	Major facilitator Superfamily
AM408_RS09085	COG3443	Belongs to the bacterial solute-binding protein 9 family
AM408_RS09100	COG2351	hydroxyisourate hydrolase activity
AM408_RS09105	COG0745	RESPONSE REGULATOR receiver
AM408_RS09110	COG2205	protein histidine kinase activity
AM408_RS09125	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AM408_RS09135	COG1418	mRNA catabolic process
AM408_RS09140	COG0270	DNA (cytosine-5-)-methyltransferase activity
AM408_RS09145	COG3727	T/G mismatch-specific endonuclease activity
AM408_RS09150	COG0697	spore germination
AM408_RS09155	COG2354	Protein conserved in bacteria
AM408_RS09160	COG5475	Uncharacterized small protein (DUF2158)
AM408_RS09195	COG2197	response regulator
AM408_RS09200	COG1684	flagellar biosynthetic protein fliR
AM408_RS09205	COG1987	bacterial-type flagellum assembly
AM408_RS09210	COG1338	Plays a role in the flagellum-specific transport system
AM408_RS09215	COG3190	flagellar
AM408_RS09220	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AM408_RS09225	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AM408_RS09230	COG1580	Controls the rotational direction of flagella during chemotaxis
AM408_RS09235	COG3144	bacterial-type flagellum assembly
AM408_RS09240	COG2882	bacterial-type flagellum organization
AM408_RS09245	COG1157	protein secretion by the type III secretion system
AM408_RS09250	COG1317	bacterial-type flagellum organization
AM408_RS09255	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AM408_RS09260	COG1766	The M ring may be actively involved in energy transduction
AM408_RS09275	COG2135	peptidase activity
AM408_RS09280	COG0425	Belongs to the sulfur carrier protein TusA family
AM408_RS09285	COG2391	methyltransferase activity
AM408_RS09300	COG0366	Alpha amylase catalytic
AM408_RS09310	COG1516	flagellar protein fliS
AM408_RS09315	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AM408_RS09325	COG1191	sigma factor activity
AM408_RS09335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM408_RS09345	COG0765	amino acid transport
AM408_RS09350	COG1126	abc transporter atp-binding protein
AM408_RS09355	COG2197	response regulator
AM408_RS09365	COG2197	response regulator
AM408_RS09395	COG3012	SEC-C Motif Domain Protein
AM408_RS09395	COG3318	Belongs to the UPF0149 family
AM408_RS09400	COG0814	amino acid
AM408_RS09410	COG1528	Iron-storage protein
AM408_RS09435	COG1528	Iron-storage protein
AM408_RS09445	COG1879	ABC-type sugar transport system periplasmic component
AM408_RS09450	COG1129	ABC transporter
AM408_RS09455	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM408_RS09460	COG1877	trehalose-phosphatase activity
AM408_RS09470	COG0589	response to stress
AM408_RS09485	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AM408_RS09490	COG1360	Flagellar Motor Protein
AM408_RS09495	COG2198	Histidine kinase
AM408_RS09495	COG0643	Histidine kinase
AM408_RS09500	COG0835	chemotaxis
AM408_RS09505	COG0840	transmembrane signaling receptor activity
AM408_RS09510	COG0840	transmembrane signaling receptor activity
AM408_RS09515	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AM408_RS09520	COG2201	protein-glutamate methylesterase activity
AM408_RS09525	COG0745	RESPONSE REGULATOR receiver
AM408_RS09530	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AM408_RS09535	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AM408_RS09540	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AM408_RS09550	COG3755	Protein conserved in bacteria
AM408_RS09565	COG3102	Protein conserved in bacteria
AM408_RS09575	COG3005	denitrification pathway
AM408_RS09580	COG0243	molybdopterin cofactor binding
AM408_RS09595	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AM408_RS09600	COG1801	Protein of unknown function DUF72
AM408_RS09605	COG1335	isochorismatase
AM408_RS09615	COG0494	nUDIX hydrolase
AM408_RS09620	COG0217	transcriptional regulatory protein
AM408_RS09650	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM408_RS09660	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AM408_RS09665	COG0739	heme binding
AM408_RS09670	COG1560	Kdo2-lipid A biosynthetic process
AM408_RS09675	COG0469	pyruvate kinase activity
AM408_RS09680	COG1737	Transcriptional regulator
AM408_RS09685	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AM408_RS09690	COG0129	dihydroxy-acid dehydratase activity
AM408_RS09695	COG0800	Aldolase
AM408_RS09705	COG3141	response to X-ray
AM408_RS09715	COG2979	Protein of unknown function (DUF533)
AM408_RS09725	COG1770	oligopeptidase
AM408_RS09730	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM408_RS09735	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM408_RS09745	COG2372	response to copper ion
AM408_RS09750	COG1276	copper resistance
AM408_RS09760	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AM408_RS09780	COG3008	intermembrane lipid transfer
AM408_RS09785	COG2995	paraquat-inducible protein a
AM408_RS09790	COG1956	GAF domain-containing protein
AM408_RS09800	COG0793	Belongs to the peptidase S41A family
AM408_RS09810	COG2814	Major facilitator Superfamily
AM408_RS09815	COG1414	Transcriptional regulator
AM408_RS09850	COG2226	methyltransferase
AM408_RS09870	COG3716	PTS system mannose fructose sorbose family IID component
AM408_RS09875	COG3715	PTS system
AM408_RS09880	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM408_RS09880	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM408_RS09895	COG1253	flavin adenine dinucleotide binding
AM408_RS09900	COG2200	EAL domain
AM408_RS09905	COG1760	l-serine dehydratase
AM408_RS09915	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AM408_RS09930	COG0251	oxidation-reduction process
AM408_RS09935	COG1199	ATP-dependent helicase activity
AM408_RS09940	COG1214	PFAM Peptidase M22, glycoprotease
AM408_RS09945	COG3065	identical protein binding
AM408_RS09950	COG0318	PFAM AMP-dependent synthetase and ligase
AM408_RS09955	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AM408_RS09960	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM408_RS09965	COG4638	Rieske (2fe-2S)
AM408_RS09970	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM408_RS09975	COG0473	3-isopropylmalate dehydrogenase activity
AM408_RS09980	COG0583	DNA-binding transcription factor activity
AM408_RS09990	COG3615	Tellurite resistance protein tehB
AM408_RS10000	COG2261	transglycosylase associated protein
AM408_RS10015	COG2199	diguanylate cyclase activity
AM408_RS10015	COG2203	Gaf domain
AM408_RS10020	COG3042	response to heat
AM408_RS10025	COG3189	MarR family transcriptional regulator
AM408_RS10030	COG2807	transmembrane transport
AM408_RS10035	COG2207	Transcriptional regulator
AM408_RS10050	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AM408_RS10055	COG2199	diguanylate cyclase activity
AM408_RS10060	COG2199	diguanylate cyclase activity
AM408_RS10070	COG2766	serine protein kinase
AM408_RS10075	COG3713	MltA-interacting MipA family protein
AM408_RS10080	COG0656	L-ascorbic acid biosynthetic process
AM408_RS10085	COG0676	glucose-6-phosphate 1-epimerase activity
AM408_RS10090	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AM408_RS10100	COG3139	Protein of unknown function (DUF1315)
AM408_RS10105	COG1063	alcohol dehydrogenase
AM408_RS10110	COG2271	Major facilitator Superfamily
AM408_RS10115	COG1063	alcohol dehydrogenase
AM408_RS10120	COG0191	fructose-bisphosphate aldolase activity
AM408_RS10125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM408_RS10130	COG0667	Aldo Keto reductase
AM408_RS10135	COG1349	DNA-binding transcription factor activity
AM408_RS10140	COG2814	Major facilitator Superfamily
AM408_RS10150	COG2814	Major facilitator Superfamily
AM408_RS10155	COG1335	isochorismatase
AM408_RS10160	COG0252	asparaginase activity
AM408_RS10165	COG0616	signal peptide processing
AM408_RS10175	COG0778	Nitroreductase
AM408_RS10190	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AM408_RS10200	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AM408_RS10210	COG0494	nUDIX hydrolase
AM408_RS10215	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AM408_RS10220	COG2897	thiosulfate sulfurtransferase activity
AM408_RS10225	COG4136	ATPase activity
AM408_RS10230	COG4135	transport system, permease component
AM408_RS10235	COG4134	Bacterial extracellular solute-binding protein
AM408_RS10240	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM408_RS10245	COG0398	Pfam SNARE associated Golgi protein
AM408_RS10255	COG0398	Pfam SNARE associated Golgi protein
AM408_RS10260	COG0708	Exodeoxyribonuclease III
AM408_RS10295	COG3678	ATP-independent chaperone mediated protein folding
AM408_RS10305	COG0322	excinuclease ABC activity
AM408_RS10315	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM408_RS10325	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM408_RS10330	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM408_RS10335	COG1447	Phosphotransferase system cellobiose-specific component IIA
AM408_RS10340	COG1917	Cupin 2, conserved barrel domain protein
AM408_RS10340	COG2169	Transcriptional regulator
AM408_RS10345	COG1486	melibiose metabolic process
AM408_RS10355	COG0753	catalase activity
AM408_RS10370	COG1823	symporter activity
AM408_RS10375	COG1988	membrane-bound metal-dependent
AM408_RS10380	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM408_RS10390	COG3001	Fructosamine kinase
AM408_RS10400	COG1105	Belongs to the carbohydrate kinase PfkB family
AM408_RS10405	COG3137	Salt-induced outer membrane protein
AM408_RS10450	COG0072	phenylalanine-tRNA ligase activity
AM408_RS10450	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM408_RS10465	COG0386	Belongs to the glutathione peroxidase family
AM408_RS10475	COG0791	NLP P60 protein
AM408_RS10480	COG2200	EAL domain
AM408_RS10490	COG4256	Hemin uptake protein
AM408_RS10495	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM408_RS10510	COG0574	Belongs to the PEP-utilizing enzyme family
AM408_RS10510	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM408_RS10515	COG0318	PFAM AMP-dependent synthetase and ligase
AM408_RS10520	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AM408_RS10525	COG0644	oxidoreductase
AM408_RS10530	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AM408_RS10535	COG2086	electron transfer activity
AM408_RS10545	COG1917	Cupin 2, conserved barrel domain protein
AM408_RS10545	COG2207	Transcriptional regulator
AM408_RS10550	COG1960	acyl-CoA dehydrogenase activity
AM408_RS10555	COG4670	ketone body catabolic process
AM408_RS10570	COG2271	Major facilitator Superfamily
AM408_RS10575	COG0738	Major facilitator superfamily
AM408_RS10590	COG0628	permease
AM408_RS10600	COG0247	lactate metabolic process
AM408_RS10600	COG0277	FAD linked oxidase domain protein
AM408_RS10605	COG2050	protein possibly involved in aromatic compounds catabolism
AM408_RS10615	COG0316	Belongs to the HesB IscA family
AM408_RS10620	COG0719	Fe-S assembly protein
AM408_RS10625	COG0396	ATPase activity
AM408_RS10630	COG0719	Fe-S assembly protein
AM408_RS10645	COG1376	ErfK ybiS ycfS ynhG family protein
AM408_RS10650	COG4238	major outer membrane lipoprotein
AM408_RS10655	COG0469	pyruvate kinase activity
AM408_RS10665	COG0437	4 iron, 4 sulfur cluster binding
AM408_RS10670	COG2414	aldehyde ferredoxin oxidoreductase
AM408_RS10680	COG0437	4 iron, 4 sulfur cluster binding
AM408_RS10685	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
AM408_RS10695	COG4529	Protein conserved in bacteria
AM408_RS10715	COG3468	outer membrane autotransporter barrel domain protein
AM408_RS10725	COG0307	riboflavin synthase, alpha
AM408_RS10730	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AM408_RS10735	COG2814	Major facilitator Superfamily
AM408_RS10740	COG0583	DNA-binding transcription factor activity
AM408_RS10760	COG2814	Major facilitator Superfamily
AM408_RS10765	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AM408_RS10770	COG0791	NLP P60 protein
AM408_RS10775	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AM408_RS10780	COG1201	RNA secondary structure unwinding
AM408_RS10785	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM408_RS10790	COG0346	lactoylglutathione lyase activity
AM408_RS10795	COG1902	pentaerythritol trinitrate reductase activity
AM408_RS10800	COG1309	transcriptional regulator
AM408_RS10805	COG3313	Fe-S protein
AM408_RS10810	COG4989	oxidoreductase activity
AM408_RS10815	COG2032	superoxide dismutase activity
AM408_RS10820	COG1289	transmembrane transporter activity
AM408_RS10825	COG1566	PFAM secretion protein HlyD family protein
AM408_RS10840	COG3133	Outer membrane lipoprotein
AM408_RS10850	COG3895	Periplasmic Protein
AM408_RS10865	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AM408_RS10870	COG0625	glutathione transferase activity
AM408_RS10875	COG3104	oligopeptide transport
AM408_RS10885	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AM408_RS10895	COG4659	FMN binding
AM408_RS10940	COG0673	inositol 2-dehydrogenase activity
AM408_RS10950	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AM408_RS10955	COG1263	PTS System
AM408_RS10955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM408_RS10960	COG1609	Transcriptional regulator
AM408_RS10965	COG1028	Short-chain dehydrogenase reductase Sdr
AM408_RS10970	COG1309	transcriptional regulator
AM408_RS10975	COG3250	beta-galactosidase activity
AM408_RS10990	COG5339	Protein conserved in bacteria
AM408_RS10995	COG1482	cell wall glycoprotein biosynthetic process
AM408_RS11000	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AM408_RS11000	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AM408_RS11005	COG0114	fumarate hydratase activity
AM408_RS11015	COG2205	protein histidine kinase activity
AM408_RS11020	COG0745	RESPONSE REGULATOR receiver
AM408_RS11025	COG3136	membrane protein required for alginate biosynthesis
AM408_RS11035	COG0531	amino acid
AM408_RS11050	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AM408_RS11055	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AM408_RS11060	COG0628	permease
AM408_RS11080	COG3591	Belongs to the peptidase S1B family
AM408_RS11100	COG2814	Major facilitator Superfamily
AM408_RS11105	COG0583	DNA-binding transcription factor activity
AM408_RS11110	COG1940	carbohydrate kinase activity
AM408_RS11115	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AM408_RS11125	COG3381	protein complex oligomerization
AM408_RS11130	COG3302	dmso reductase anchor subunit
AM408_RS11135	COG0437	4 iron, 4 sulfur cluster binding
AM408_RS11140	COG0243	molybdopterin cofactor binding
AM408_RS11145	COG0243	molybdopterin cofactor binding
AM408_RS11160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM408_RS11180	COG4948	Mandelate Racemase Muconate Lactonizing
AM408_RS11185	COG1063	alcohol dehydrogenase
AM408_RS11190	COG0477	Major facilitator Superfamily
AM408_RS11195	COG0246	Mannitol dehydrogenase
AM408_RS11205	COG1802	Transcriptional regulator
AM408_RS11210	COG4221	oxidoreductase activity
AM408_RS11220	COG0339	signal peptide processing
AM408_RS11225	COG1546	Belongs to the CinA family
AM408_RS11230	COG3111	PFAM Bacterial OB fold (BOF) protein
AM408_RS11235	COG3706	GGDEF domain
AM408_RS11245	COG2814	Major facilitator Superfamily
AM408_RS11250	COG0697	spore germination
AM408_RS11260	COG4977	sequence-specific DNA binding
AM408_RS11265	COG1846	Transcriptional regulator
AM408_RS11285	COG0583	DNA-binding transcription factor activity
AM408_RS11290	COG1012	belongs to the aldehyde dehydrogenase family
AM408_RS11295	COG2066	Belongs to the glutaminase family
AM408_RS11305	COG2199	diguanylate cyclase activity
AM408_RS11325	COG3781	membrane
AM408_RS11375	COG2911	Protein conserved in bacteria
AM408_RS11375	COG3210	domain, Protein
AM408_RS11380	COG1396	sequence-specific DNA binding
AM408_RS11385	COG3550	peptidyl-serine autophosphorylation
AM408_RS11400	COG3188	usher protein
AM408_RS11405	COG3539	Fimbrial protein
AM408_RS11410	COG3539	Fimbrial protein
AM408_RS11415	COG3539	Fimbrial protein
AM408_RS11420	COG0243	molybdopterin cofactor binding
AM408_RS11430	COG2207	Transcriptional regulator
AM408_RS11435	COG3119	arylsulfatase activity
AM408_RS11440	COG0641	radical SAM
AM408_RS11445	COG4178	(ABC) transporter
AM408_RS11450	COG4771	TonB-dependent receptor
AM408_RS11455	COG0612	Peptidase, M16
AM408_RS11460	COG0076	glutamate decarboxylase activity
AM408_RS11465	COG0531	amino acid
AM408_RS11470	COG1649	PFAM Uncharacterised BCR, COG1649
AM408_RS11475	COG3706	GGDEF domain
AM408_RS11480	COG2202	Pas domain
AM408_RS11480	COG2200	EAL domain
AM408_RS11480	COG2199	diguanylate cyclase activity
AM408_RS11485	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AM408_RS11490	COG0747	negative chemotaxis
AM408_RS11495	COG0601	transmembrane transport
AM408_RS11500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM408_RS11505	COG0444	Belongs to the ABC transporter superfamily
AM408_RS11510	COG4608	Belongs to the ABC transporter superfamily
AM408_RS11515	COG1764	response to oxidative stress
AM408_RS11540	COG1064	alcohol dehydrogenase
AM408_RS11545	COG3093	addiction module antidote protein HigA
AM408_RS11550	COG2864	formate dehydrogenase
AM408_RS11555	COG0437	4 iron, 4 sulfur cluster binding
AM408_RS11565	COG0697	spore germination
AM408_RS11570	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AM408_RS11575	COG4886	Leucine-rich repeat (LRR) protein
AM408_RS11585	COG2223	nitrite transmembrane transporter activity
AM408_RS11590	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AM408_RS11595	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AM408_RS11600	COG1140	nitrate reductase beta subunit
AM408_RS11605	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AM408_RS11610	COG2181	nitrate reductase activity
AM408_RS11615	COG0384	phenazine biosynthesis protein PhzF
AM408_RS11620	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AM408_RS11625	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM408_RS11635	COG5433	transposase activity
AM408_RS11655	COG3209	COG3209 Rhs family protein
AM408_RS11670	COG0625	glutathione transferase activity
AM408_RS11675	COG1113	amino acid transport
AM408_RS11680	COG3391	amine dehydrogenase activity
AM408_RS11695	COG4772	TonB-dependent receptor
AM408_RS11700	COG1802	Transcriptional regulator
AM408_RS11705	COG2130	NADP-dependent
AM408_RS11715	COG1247	-acetyltransferase
AM408_RS11720	COG3238	Protein conserved in bacteria
AM408_RS11750	COG1177	transmembrane transport
AM408_RS11755	COG1176	ABC-type spermidine putrescine transport system, permease component I
AM408_RS11760	COG3842	ATPase activity
AM408_RS11765	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AM408_RS11770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM408_RS11775	COG1598	PFAM Uncharacterised protein family UPF0150
AM408_RS11780	COG1724	mRNA binding
AM408_RS11790	COG0826	peptidase U32
AM408_RS11795	COG1396	sequence-specific DNA binding
AM408_RS11800	COG3135	benzoate transporter
AM408_RS11805	COG0675	Transposase, IS605 OrfB family
AM408_RS11820	COG0500	methyltransferase
AM408_RS11825	COG1275	C4-dicarboxylate transporter malic acid transport protein
AM408_RS11830	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM408_RS11835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM408_RS11840	COG2841	Protein conserved in bacteria
AM408_RS11860	COG5383	Protein conserved in bacteria
AM408_RS11865	COG0583	DNA-binding transcription factor activity
AM408_RS11870	COG0840	transmembrane signaling receptor activity
AM408_RS11885	COG3038	cytochrome b561
AM408_RS11890	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AM408_RS11895	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AM408_RS11905	COG1012	belongs to the aldehyde dehydrogenase family
AM408_RS11910	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AM408_RS11915	COG1643	Atp-dependent helicase
AM408_RS11925	COG0671	phosphoesterase, PA-phosphatase related
AM408_RS11925	COG2453	phosphatase
AM408_RS11930	COG2267	carboxylic ester hydrolase activity
AM408_RS11935	COG4589	Belongs to the CDS family
AM408_RS11940	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AM408_RS11950	COG0667	Aldo Keto reductase
AM408_RS11980	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM408_RS11985	COG3327	negative regulation of DNA-templated transcription, initiation
AM408_RS11990	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AM408_RS11995	COG0183	Belongs to the thiolase family
AM408_RS12000	COG2050	protein possibly involved in aromatic compounds catabolism
AM408_RS12005	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM408_RS12010	COG1024	Enoyl-CoA hydratase
AM408_RS12015	COG1024	Enoyl-CoA hydratase
AM408_RS12020	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM408_RS12025	COG2151	metal-sulfur cluster biosynthetic enzyme
AM408_RS12030	COG3396	Phenylacetate-CoA oxygenase
AM408_RS12035	COG3460	Phenylacetate-CoA oxygenase
AM408_RS12040	COG3396	Phenylacetate-CoA oxygenase
AM408_RS12045	COG1012	belongs to the aldehyde dehydrogenase family
AM408_RS12045	COG2030	dehydratase
AM408_RS12050	COG3733	amine oxidase
AM408_RS12055	COG1012	belongs to the aldehyde dehydrogenase family
AM408_RS12060	COG2207	Transcriptional regulator
AM408_RS12065	COG3784	Protein of unknown function (DUF1318)
AM408_RS12075	COG2911	Protein conserved in bacteria
AM408_RS12080	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AM408_RS12085	COG3187	Heat shock protein
AM408_RS12090	COG3042	response to heat
AM408_RS12095	COG0674	pyruvate-flavodoxin oxidoreductase activity
AM408_RS12095	COG1013	pyruvate-flavodoxin oxidoreductase activity
AM408_RS12095	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM408_RS12095	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AM408_RS12105	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AM408_RS12110	COG0589	response to stress
AM408_RS12120	COG0513	Belongs to the DEAD box helicase family
AM408_RS12135	COG3706	GGDEF domain
AM408_RS12140	COG2840	Smr protein MutS2
AM408_RS12150	COG0583	DNA-binding transcription factor activity
AM408_RS12155	COG1473	amidohydrolase
AM408_RS12160	COG1473	amidohydrolase
AM408_RS12170	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AM408_RS12175	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM408_RS12180	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM408_RS12185	COG0589	response to stress
AM408_RS12190	COG3182	Iron-regulated membrane protein
AM408_RS12195	COG0668	transmembrane transport
AM408_RS12200	COG4166	transmembrane transport
AM408_RS12205	COG0583	DNA-binding transcription factor activity
AM408_RS12210	COG1073	alpha beta
AM408_RS12215	COG0702	epimerase
AM408_RS12220	COG2866	Carboxypeptidase
AM408_RS12225	COG4948	Mandelate Racemase Muconate Lactonizing
AM408_RS12230	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AM408_RS12235	COG3283	Transcriptional regulator of aromatic amino acids metabolism
AM408_RS12245	COG3106	COG3106 Predicted ATPase
AM408_RS12250	COG1609	Transcriptional regulator
AM408_RS12260	COG3842	ATPase activity
AM408_RS12265	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM408_RS12270	COG1554	hydrolase, family 65, central catalytic
AM408_RS12275	COG0673	inositol 2-dehydrogenase activity
AM408_RS12280	COG1082	Xylose isomerase domain protein TIM barrel
AM408_RS12285	COG1063	alcohol dehydrogenase
AM408_RS12290	COG0395	ABC-type sugar transport system, permease component
AM408_RS12295	COG1175	transmembrane transport
AM408_RS12305	COG0366	Alpha amylase catalytic
AM408_RS12310	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AM408_RS12320	COG1983	PspC domain protein
AM408_RS12330	COG1842	Phage shock protein A
AM408_RS12335	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AM408_RS12340	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AM408_RS12345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM408_RS12350	COG1012	belongs to the aldehyde dehydrogenase family
AM408_RS12360	COG1396	sequence-specific DNA binding
AM408_RS12360	COG1917	Cupin 2, conserved barrel domain protein
AM408_RS12365	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AM408_RS12370	COG0174	glutamine synthetase
AM408_RS12375	COG0531	amino acid
AM408_RS12390	COG4166	transmembrane transport
AM408_RS12395	COG4168	peptide transport system, permease
AM408_RS12400	COG4171	peptide transport system, permease
AM408_RS12405	COG4172	Belongs to the ABC transporter superfamily
AM408_RS12410	COG4172	Belongs to the ABC transporter superfamily
AM408_RS12415	COG2852	Protein conserved in bacteria
AM408_RS12420	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AM408_RS12425	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM408_RS12425	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM408_RS12440	COG5001	Diguanylate cyclase
AM408_RS12450	COG1349	DNA-binding transcription factor activity
AM408_RS12460	COG0023	Translation Initiation Factor
AM408_RS12470	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AM408_RS12475	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AM408_RS12480	COG0671	phosphoesterase, PA-phosphatase related
AM408_RS12490	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AM408_RS12520	COG0583	DNA-binding transcription factor activity
AM408_RS12530	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AM408_RS12545	COG0616	signal peptide processing
AM408_RS12550	COG1028	Short-chain dehydrogenase reductase Sdr
AM408_RS12555	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
AM408_RS12560	COG1187	pseudouridine synthase activity
AM408_RS12565	COG4907	membrane protein (DUF2207)
AM408_RS12570	COG0009	L-threonylcarbamoyladenylate synthase
AM408_RS12575	COG0613	PHP domain protein
AM408_RS12585	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AM408_RS12590	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AM408_RS12590	COG0512	Glutamine amidotransferase of anthranilate synthase
AM408_RS12595	COG0135	phosphoribosylanthranilate isomerase activity
AM408_RS12595	COG0134	indole-3-glycerol-phosphate synthase activity
AM408_RS12610	COG3729	General stress protein
AM408_RS12615	COG3685	Protein conserved in bacteria
AM408_RS12620	COG3685	Protein conserved in bacteria
AM408_RS12625	COG3047	cAMP biosynthetic process
AM408_RS12645	COG1607	acyl-coa hydrolase
AM408_RS12650	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AM408_RS12655	COG2350	Protein conserved in bacteria
AM408_RS12660	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM408_RS12680	COG4608	Belongs to the ABC transporter superfamily
AM408_RS12685	COG0444	Belongs to the ABC transporter superfamily
AM408_RS12690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM408_RS12695	COG0601	transmembrane transport
AM408_RS12700	COG4166	transmembrane transport
AM408_RS12710	COG2095	MarC family integral membrane protein
AM408_RS12715	COG1454	alcohol dehydrogenase
AM408_RS12715	COG1012	belongs to the aldehyde dehydrogenase family
AM408_RS12725	COG1435	thymidine kinase activity
AM408_RS12735	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AM408_RS12740	COG0745	RESPONSE REGULATOR receiver
AM408_RS12745	COG1752	Esterase of the alpha-beta hydrolase superfamily
AM408_RS12755	COG0788	formyltetrahydrofolate deformylase activity
AM408_RS12790	COG2181	nitrate reductase activity
AM408_RS12795	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AM408_RS12800	COG1140	nitrate reductase beta subunit
AM408_RS12805	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AM408_RS12810	COG2223	nitrite transmembrane transporter activity
AM408_RS12820	COG3850	Histidine kinase
AM408_RS12825	COG2197	response regulator
AM408_RS12830	COG4932	domain protein
AM408_RS12835	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AM408_RS12840	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AM408_RS12845	COG4572	Cation transport regulator
AM408_RS12850	COG0387	Pfam Sodium calcium exchanger
AM408_RS12885	COG2912	Transglutaminase-like superfamily
AM408_RS12890	COG3094	Invasion gene expression up-regulator, SirB
AM408_RS12895	COG2890	protein-(glutamine-N5) methyltransferase activity
AM408_RS12920	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AM408_RS12925	COG0659	secondary active sulfate transmembrane transporter activity
AM408_RS12940	COG0012	GTP binding
AM408_RS12955	COG3468	outer membrane autotransporter barrel domain protein
AM408_RS12960	COG3284	Transcriptional regulator
AM408_RS12965	COG2376	Dihydroxyacetone kinase
AM408_RS12970	COG1461	Dihydroxyacetone kinase
AM408_RS12975	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
AM408_RS12975	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM408_RS12975	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM408_RS12995	COG2261	transglycosylase associated protein
AM408_RS13000	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
AM408_RS13015	COG1619	proteins homologs of microcin C7 resistance protein MccF
AM408_RS13025	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AM408_RS13035	COG2719	SpoVR family
AM408_RS13050	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AM408_RS13055	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AM408_RS13060	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AM408_RS13075	COG0179	Fumarylacetoacetate (FAA) hydrolase
AM408_RS13110	COG2894	cell division
AM408_RS13165	COG2200	EAL domain
AM408_RS13190	COG2200	EAL domain
AM408_RS13195	COG0789	Transcriptional regulator
AM408_RS13200	COG5562	phage envelope protein
AM408_RS13210	COG0538	isocitrate dehydrogenase activity
AM408_RS13215	COG1187	pseudouridine synthase activity
AM408_RS13235	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AM408_RS13240	COG0745	RESPONSE REGULATOR receiver
AM408_RS13245	COG2205	protein histidine kinase activity
AM408_RS13250	COG2850	peptidyl-arginine hydroxylation
AM408_RS13265	COG3842	ATPase activity
AM408_RS13280	COG0500	methyltransferase
AM408_RS13315	COG3344	reverse transcriptase
AM408_RS13330	COG5301	cellulose 1,4-beta-cellobiosidase activity
AM408_RS13455	COG3772	lysozyme
AM408_RS13500	COG0484	heat shock protein binding
AM408_RS13505	COG4584	PFAM Integrase catalytic
AM408_RS13510	COG1484	DNA-dependent DNA replication
AM408_RS13515	COG0484	heat shock protein binding
AM408_RS13520	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
AM408_RS13525	COG1403	HNH endonuclease
AM408_RS13610	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM408_RS13620	COG0582	viral genome integration into host DNA
AM408_RS13625	COG1177	transmembrane transport
AM408_RS13630	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AM408_RS13640	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AM408_RS13645	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AM408_RS13655	COG4591	ABC-type transport system involved in lipoprotein release permease component
AM408_RS13660	COG1136	(ABC) transporter
AM408_RS13665	COG4591	ABC-type transport system involved in lipoprotein release permease component
AM408_RS13670	COG4763	Acyl-transferase
AM408_RS13675	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AM408_RS13680	COG1388	LysM domain
AM408_RS13680	COG1376	ErfK ybiS ycfS ynhG family protein
AM408_RS13690	COG1309	transcriptional regulator
AM408_RS13695	COG3134	Outer membrane lipoprotein
AM408_RS13705	COG1252	NADH dehydrogenase
AM408_RS13725	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
AM408_RS13730	COG5633	Lipoprotein
AM408_RS13735	COG0537	adenosine 5'-monophosphoramidase activity
AM408_RS13740	COG4773	Receptor
AM408_RS13745	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM408_RS13745	COG1263	PTS System
AM408_RS13750	COG0084	hydrolase, TatD family'
AM408_RS13755	COG0470	DNA polymerase III
AM408_RS13765	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AM408_RS13770	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AM408_RS13775	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM408_RS13785	COG1028	Short-chain dehydrogenase reductase Sdr
AM408_RS13790	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AM408_RS13810	COG1399	metal-binding, possibly nucleic acid-binding protein
AM408_RS13815	COG0424	maF-like protein
AM408_RS13820	COG0564	pseudouridine synthase activity
AM408_RS13835	COG1530	ribonuclease E activity
AM408_RS13840	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AM408_RS13845	COG1256	bacterial-type flagellum assembly
AM408_RS13850	COG3951	Flagellar rod assembly protein muramidase FlgJ
AM408_RS13850	COG1705	Flagellar rod assembly protein muramidase FlgJ
AM408_RS13865	COG4786	Flagellar basal body rod
AM408_RS13870	COG4787	bacterial-type flagellum-dependent cell motility
AM408_RS13875	COG1749	Flagellar hook protein flgE
AM408_RS13880	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AM408_RS13885	COG1558	bacterial-type flagellum-dependent cell motility
AM408_RS13890	COG1815	bacterial-type flagellum-dependent cell motility
AM408_RS13895	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
AM408_RS13900	COG2747	anti-sigma28 factor FlgM
AM408_RS13905	COG3418	PFAM FlgN family protein
AM408_RS13910	COG0728	peptidoglycan biosynthetic process
AM408_RS13915	COG0673	inositol 2-dehydrogenase activity
AM408_RS13925	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM408_RS13935	COG2999	glutathione oxidoreductase activity
AM408_RS13970	COG3038	cytochrome b561
AM408_RS13975	COG2353	YceI-like domain
AM408_RS13985	COG1560	Kdo2-lipid A biosynthetic process
AM408_RS14000	COG5645	(Lipo)protein
AM408_RS14005	COG2943	transferase activity, transferring hexosyl groups
AM408_RS14030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM408_RS14035	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AM408_RS14070	COG2197	response regulator
AM408_RS14085	COG1462	curli production assembly transport component CsgG
AM408_RS14095	COG3381	protein complex oligomerization
AM408_RS14135	COG3706	GGDEF domain
AM408_RS14140	COG0457	Tetratricopeptide repeat
AM408_RS14145	COG0726	polysaccharide deacetylase
AM408_RS14145	COG1649	PFAM Uncharacterised BCR, COG1649
AM408_RS14150	COG1215	transferase activity, transferring glycosyl groups
AM408_RS14155	COG3658	cytochrome
AM408_RS14160	COG1702	phosphate starvation-inducible protein PhoH
AM408_RS14170	COG2837	iron assimilation
AM408_RS14175	COG2822	iron ion transport
AM408_RS14195	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AM408_RS14210	COG0506	proline dehydrogenase activity
AM408_RS14210	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AM408_RS14210	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AM408_RS14215	COG1309	transcriptional regulator
AM408_RS14250	COG2233	PERMEase
AM408_RS14255	COG3729	General stress protein
AM408_RS14295	COG3381	protein complex oligomerization
AM408_RS14300	COG0243	molybdopterin cofactor binding
AM408_RS14305	COG3005	denitrification pathway
AM408_RS14310	COG0745	RESPONSE REGULATOR receiver
AM408_RS14315	COG1879	ABC-type sugar transport system periplasmic component
AM408_RS14320	COG2198	Histidine kinase
AM408_RS14320	COG0784	Response regulator, receiver
AM408_RS14320	COG2205	protein histidine kinase activity
AM408_RS14325	COG0348	domain, Protein
AM408_RS14345	COG1278	Cold shock
AM408_RS14350	COG1278	Cold shock
AM408_RS14370	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM408_RS14375	COG1596	polysaccharide export
AM408_RS14380	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AM408_RS14385	COG0489	protein tyrosine kinase activity
AM408_RS14385	COG3206	protein involved in exopolysaccharide biosynthesis
AM408_RS14400	COG1294	oxidase, subunit
AM408_RS14405	COG1271	oxidase subunit
AM408_RS14410	COG1773	rubredoxin
AM408_RS14415	COG1999	signal sequence binding
AM408_RS14420	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AM408_RS14425	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
AM408_RS14430	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AM408_RS14435	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AM408_RS14445	COG0670	Belongs to the BI1 family
AM408_RS14450	COG2920	part of a sulfur-relay system
AM408_RS14455	COG1254	Belongs to the acylphosphatase family
AM408_RS14470	COG1832	CoA-binding protein
AM408_RS14485	COG0210	DNA helicase
AM408_RS14490	COG3304	Inner membrane component domain
AM408_RS14495	COG1289	transmembrane transporter activity
AM408_RS14500	COG3070	regulator of competence-specific genes
AM408_RS14515	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AM408_RS14515	COG2885	chlorophyll binding
AM408_RS14525	COG1067	ATP-dependent peptidase activity
AM408_RS14535	COG3130	regulation of translation
AM408_RS14540	COG3009	Protein conserved in bacteria
AM408_RS14545	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AM408_RS14545	COG3008	intermembrane lipid transfer
AM408_RS14550	COG2995	paraquat-inducible protein a
AM408_RS14555	COG0488	(ABC) transporter
AM408_RS14565	COG0633	Ferredoxin
AM408_RS14565	COG3217	Mosc domain protein beta barrel domain protein
AM408_RS14580	COG3121	Chaperone
AM408_RS14585	COG3539	Fimbrial protein
AM408_RS14590	COG3539	Fimbrial protein
AM408_RS14595	COG3539	Fimbrial protein
AM408_RS14600	COG3188	usher protein
AM408_RS14605	COG3121	Chaperone
AM408_RS14610	COG3539	Fimbrial protein
AM408_RS14620	COG0431	NADPH-dependent FMN reductase
AM408_RS14625	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM408_RS14635	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM408_RS14640	COG1116	anion transmembrane transporter activity
AM408_RS14645	COG0308	aminopeptidase N
AM408_RS14670	COG1448	Aminotransferase
AM408_RS14680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM408_RS14685	COG3108	Peptidase M15
AM408_RS14695	COG2989	Protein conserved in bacteria
AM408_RS14705	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
AM408_RS14715	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AM408_RS14725	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AM408_RS14730	COG3173	Aminoglycoside phosphotransferase
AM408_RS14745	COG3214	Protein conserved in bacteria
AM408_RS14750	COG1663	tetraacyldisaccharide 4'-kinase activity
AM408_RS14755	COG1132	(ABC) transporter
AM408_RS14760	COG0658	competence protein
AM408_RS14760	COG2333	competence protein COMEC
AM408_RS14770	COG0539	negative regulation of cytoplasmic translation
AM408_RS14780	COG0501	Belongs to the peptidase M48B family
AM408_RS14795	COG2323	membrane
AM408_RS14800	COG1944	ATP diphosphatase activity
AM408_RS14805	COG2116	formate transmembrane transporter activity
AM408_RS14810	COG1882	Formate acetyltransferase
AM408_RS14815	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM408_RS14820	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM408_RS14825	COG0583	DNA-binding transcription factor activity
AM408_RS14830	COG0531	amino acid
AM408_RS14840	COG1335	isochorismatase
AM408_RS14845	COG3302	dmso reductase anchor subunit
AM408_RS14850	COG0437	4 iron, 4 sulfur cluster binding
AM408_RS14855	COG0243	molybdopterin cofactor binding
AM408_RS14865	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AM408_RS14875	COG1674	ftsk spoiiie
AM408_RS14875	COG1178	ABC-type Fe3 transport system permease component
AM408_RS14880	COG1522	sequence-specific DNA binding
AM408_RS14890	COG0492	ferredoxin-NADP+ reductase activity
AM408_RS14895	COG4988	ABC transporter
AM408_RS14900	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AM408_RS14925	COG0542	response to heat
AM408_RS14935	COG1278	Cold shock
AM408_RS14940	COG0577	efflux transmembrane transporter activity
AM408_RS14940	COG1136	(ABC) transporter
AM408_RS14945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM408_RS14950	COG2990	Protein conserved in bacteria
AM408_RS14955	COG3593	DNA synthesis involved in DNA repair
AM408_RS14970	COG2431	L-lysine efflux transmembrane transporter activity
AM408_RS14980	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM408_RS14985	COG0028	Belongs to the TPP enzyme family
AM408_RS14990	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AM408_RS14995	COG0702	epimerase
AM408_RS15000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM408_RS15005	COG3023	N-Acetylmuramoyl-L-alanine amidase
AM408_RS15020	COG1126	abc transporter atp-binding protein
AM408_RS15025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM408_RS15030	COG4215	(ABC) transporter
AM408_RS15035	COG4160	amino acid transport
AM408_RS15040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM408_RS15055	COG1177	transmembrane transport
AM408_RS15060	COG1176	ABC-type spermidine putrescine transport system, permease component I
AM408_RS15065	COG3842	ATPase activity
AM408_RS15070	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AM408_RS15090	COG0778	Nitroreductase
AM408_RS15100	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM408_RS15115	COG3226	Transcriptional regulator
AM408_RS15120	COG0738	Major facilitator superfamily
AM408_RS15125	COG0561	phosphatase activity
AM408_RS15135	COG2814	Major facilitator Superfamily
AM408_RS15140	COG0671	phosphoesterase, PA-phosphatase related
AM408_RS15145	COG1349	DNA-binding transcription factor activity
AM408_RS15150	COG1686	Belongs to the peptidase S11 family
AM408_RS15155	COG0625	glutathione transferase activity
AM408_RS15160	COG2133	pyrroloquinoline quinone binding
AM408_RS15175	COG2199	diguanylate cyclase activity
AM408_RS15185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM408_RS15195	COG0747	negative chemotaxis
AM408_RS15200	COG4172	Belongs to the ABC transporter superfamily
AM408_RS15205	COG1446	asparaginase
AM408_RS15210	COG0303	'Molybdopterin
AM408_RS15215	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AM408_RS15220	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM408_RS15225	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM408_RS15230	COG1882	Formate acetyltransferase
AM408_RS15235	COG0561	phosphatase activity
AM408_RS15245	COG0488	(ABC) transporter
AM408_RS15250	COG1376	ErfK ybiS ycfS ynhG family protein
AM408_RS15255	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AM408_RS15260	COG1321	iron dependent repressor
AM408_RS15270	COG2194	sulfuric ester hydrolase activity
AM408_RS15275	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AM408_RS15280	COG5006	permease, DMT superfamily
AM408_RS15305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM408_RS15310	COG0765	amino acid transport
AM408_RS15315	COG1126	abc transporter atp-binding protein
AM408_RS15320	COG0668	transmembrane transport
AM408_RS15335	COG4774	siderophore transport
AM408_RS15345	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AM408_RS15355	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AM408_RS15360	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AM408_RS15365	COG1199	ATP-dependent helicase activity
AM408_RS15375	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
AM408_RS15380	COG0513	Belongs to the DEAD box helicase family
AM408_RS15385	COG1309	transcriptional regulator
AM408_RS15395	COG1131	(ABC) transporter
AM408_RS15400	COG0842	Transport permease protein
AM408_RS15405	COG0842	Transport permease protein
AM408_RS15415	COG3568	Endonuclease Exonuclease Phosphatase
AM408_RS15420	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM408_RS15425	COG0392	lysyltransferase activity
AM408_RS15430	COG0670	Belongs to the BI1 family
AM408_RS15435	COG0670	Belongs to the BI1 family
AM408_RS15440	COG0314	molybdopterin synthase activity
AM408_RS15445	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AM408_RS15455	COG0521	Mo-molybdopterin cofactor biosynthetic process
AM408_RS15465	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AM408_RS15475	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AM408_RS15480	COG2226	methyltransferase
AM408_RS15495	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AM408_RS15500	COG1881	PFAM PEBP family protein
AM408_RS15510	COG4677	pectinesterase activity
AM408_RS15515	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AM408_RS15520	COG0471	metal ion transport
AM408_RS15525	COG2828	Protein conserved in bacteria
AM408_RS15530	COG0583	DNA-binding transcription factor activity
AM408_RS15540	COG0561	phosphatase activity
AM408_RS15545	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AM408_RS15550	COG4149	molybdate abc transporter
AM408_RS15555	COG0725	ABC transporter, periplasmic molybdate-binding protein
AM408_RS15570	COG2005	Transcriptional regulator
AM408_RS15570	COG3585	molybdate ion transport
AM408_RS15575	COG1119	ATPase activity
AM408_RS15580	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AM408_RS15585	COG1085	galactose-1-phosphate uridylyltransferase
AM408_RS15595	COG2017	converts alpha-aldose to the beta-anomer
AM408_RS15605	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM408_RS15620	COG1230	cation diffusion facilitator family transporter
AM408_RS15625	COG3201	nicotinamide mononucleotide transporter
AM408_RS15675	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AM408_RS15680	COG2885	chlorophyll binding
AM408_RS15690	COG3064	Membrane
AM408_RS15695	COG0848	biopolymer transport protein
AM408_RS15700	COG0811	peptide transport
AM408_RS15705	COG0824	Thioesterase
AM408_RS15710	COG3790	cyd operon protein YbgE
AM408_RS15715	COG4890	Cyd operon protein YbgT
AM408_RS15720	COG1294	oxidase, subunit
AM408_RS15725	COG1271	oxidase subunit
AM408_RS15735	COG0383	alpha-mannosidase activity
AM408_RS15740	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM408_RS15740	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM408_RS15740	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM408_RS15745	COG2188	Transcriptional regulator
AM408_RS15750	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AM408_RS15760	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM408_RS15765	COG0567	Dehydrogenase, E1 component
AM408_RS15770	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AM408_RS15775	COG1053	succinate dehydrogenase
AM408_RS15780	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AM408_RS15785	COG2009	succinate dehydrogenase
AM408_RS15800	COG0372	Belongs to the citrate synthase family
AM408_RS15805	COG3539	Fimbrial protein
AM408_RS15810	COG3188	usher protein
AM408_RS15815	COG3121	Chaperone
AM408_RS15820	COG3539	Fimbrial protein
AM408_RS15825	COG3180	Ammonia monooxygenase
AM408_RS15840	COG1984	allophanate hydrolase subunit 2
AM408_RS15845	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AM408_RS15850	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AM408_RS15855	COG3104	oligopeptide transport
AM408_RS15860	COG0415	Belongs to the DNA photolyase family
AM408_RS15865	COG3272	Protein of unknown function (DUF1722)
AM408_RS15870	COG5433	transposase activity
AM408_RS15880	COG5433	transposase activity
AM408_RS15890	COG3209	COG3209 Rhs family protein
AM408_RS15900	COG3209	COG3209 Rhs family protein
AM408_RS15930	COG2205	protein histidine kinase activity
AM408_RS15935	COG0745	RESPONSE REGULATOR receiver
AM408_RS15945	COG1982	Orn Lys Arg decarboxylase major
AM408_RS15955	COG0531	amino acid
AM408_RS15975	COG0033	Phosphoglucomutase
AM408_RS15980	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AM408_RS15985	COG0596	Alpha beta hydrolase
AM408_RS15995	COG0716	FMN binding
AM408_RS16005	COG0735	belongs to the Fur family
AM408_RS16025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM408_RS16025	COG1263	PTS System
AM408_RS16025	COG2190	(PTS) system
AM408_RS16035	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AM408_RS16040	COG1846	Transcriptional regulator
AM408_RS16040	COG1940	carbohydrate kinase activity
AM408_RS16045	COG0647	UMP catabolic process
AM408_RS16055	COG0367	asparagine synthase
AM408_RS16100	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM408_RS16110	COG1702	phosphate starvation-inducible protein PhoH
AM408_RS16120	COG4535	Mg2 and Co2 transporter CorC
AM408_RS16125	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AM408_RS16130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM408_RS16135	COG0765	amino acid transport
AM408_RS16140	COG0765	amino acid transport
AM408_RS16145	COG1126	abc transporter atp-binding protein
AM408_RS16155	COG0443	Heat shock 70 kDa protein
AM408_RS16160	COG2214	Heat shock protein DnaJ domain protein
AM408_RS16170	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AM408_RS16175	COG2214	Heat shock protein DnaJ domain protein
AM408_RS16185	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AM408_RS16190	COG2888	peptidyl-tyrosine sulfation
AM408_RS16205	COG1466	dna polymerase III delta subunit
AM408_RS16215	COG0406	alpha-ribazole phosphatase activity
AM408_RS16220	COG0799	negative regulation of ribosome biogenesis
AM408_RS16230	COG0768	penicillin binding
AM408_RS16235	COG0772	Belongs to the SEDS family
AM408_RS16240	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AM408_RS16245	COG1686	Belongs to the peptidase S11 family
AM408_RS16265	COG0583	DNA-binding transcription factor activity
AM408_RS16280	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AM408_RS16285	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM408_RS16290	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM408_RS16315	COG3069	C4-dicarboxylate transmembrane transporter activity
AM408_RS16320	COG4565	transcriptional regulatory protein
AM408_RS16325	COG3290	protein histidine kinase activity
AM408_RS16330	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
AM408_RS16340	COG2301	Belongs to the HpcH HpaI aldolase family
AM408_RS16345	COG3051	citrate lyase alpha subunit
AM408_RS16360	COG0471	metal ion transport
AM408_RS16365	COG3719	Belongs to the RNase T2 family
AM408_RS16375	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AM408_RS16385	COG1063	alcohol dehydrogenase
AM408_RS16390	COG0589	response to stress
AM408_RS16395	COG3634	alkyl hydroperoxide reductase activity
AM408_RS16400	COG0450	alkyl hydroperoxide reductase
AM408_RS16405	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM408_RS16415	COG0583	DNA-binding transcription factor activity
AM408_RS16420	COG3969	phosphoadenosine phosphosulfate
AM408_RS16425	COG1475	DNA binding
AM408_RS16430	COG0436	Aminotransferase
AM408_RS16435	COG0371	Dehydrogenase
AM408_RS16440	COG2879	small protein
AM408_RS16445	COG1966	Carbon starvation protein
AM408_RS16450	COG2050	protein possibly involved in aromatic compounds catabolism
AM408_RS16455	COG1028	Short-chain dehydrogenase reductase Sdr
AM408_RS16460	COG3433	isochorismatase activity
AM408_RS16460	COG1535	isochorismatase
AM408_RS16465	COG1021	2,3-dihydroxybenzoate-AMP ligase
AM408_RS16470	COG1169	isochorismate synthase
AM408_RS16480	COG4592	Periplasmic binding protein
AM408_RS16490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM408_RS16495	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM408_RS16500	COG1120	ATPase activity
AM408_RS16505	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
AM408_RS16510	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AM408_RS16510	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM408_RS16515	COG3251	PFAM MbtH domain protein
AM408_RS16520	COG2382	esterase
AM408_RS16525	COG4771	TonB-dependent receptor
AM408_RS16530	COG2977	Belongs to the P-Pant transferase superfamily
AM408_RS16535	COG3385	transposase activity
AM408_RS16585	COG3423	Transcriptional regulator
AM408_RS16605	COG0500	methyltransferase
AM408_RS16610	COG0438	transferase activity, transferring glycosyl groups
AM408_RS16615	COG0438	transferase activity, transferring glycosyl groups
AM408_RS16665	COG0778	Nitroreductase
AM408_RS16670	COG0668	transmembrane transport
AM408_RS16675	COG1113	amino acid transport
AM408_RS16680	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM408_RS16685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM408_RS16690	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM408_RS16695	COG1538	Outer membrane efflux protein
AM408_RS16705	COG0745	RESPONSE REGULATOR receiver
AM408_RS16710	COG5002	protein histidine kinase activity
AM408_RS16715	COG1215	transferase activity, transferring glycosyl groups
AM408_RS16720	COG4783	chaperone-mediated protein folding
AM408_RS16735	COG2207	Transcriptional regulator
AM408_RS16750	COG2197	response regulator
AM408_RS16755	COG3539	Fimbrial protein
AM408_RS16760	COG3539	Fimbrial protein
AM408_RS16765	COG3188	usher protein
AM408_RS16770	COG3121	Chaperone
AM408_RS16775	COG3539	Fimbrial protein
AM408_RS16785	COG2501	S4 domain
AM408_RS16790	COG1988	membrane-bound metal-dependent
AM408_RS16800	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AM408_RS16815	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AM408_RS16820	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AM408_RS16825	COG0549	Belongs to the carbamate kinase family
AM408_RS16835	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AM408_RS16840	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AM408_RS16845	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AM408_RS16850	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AM408_RS16855	COG3257	ureidoglycine aminohydrolase activity
AM408_RS16860	COG1929	Belongs to the glycerate kinase type-1 family
AM408_RS16865	COG2233	PERMEase
AM408_RS16875	COG1953	Uracil, thiamine, allantoin
AM408_RS16880	COG2084	Dehydrogenase
AM408_RS16890	COG3960	tartronate-semialdehyde synthase activity
AM408_RS16895	COG1414	Transcriptional regulator
AM408_RS16905	COG0583	DNA-binding transcription factor activity
AM408_RS16915	COG2801	Transposase and inactivated derivatives
AM408_RS16925	COG3209	COG3209 Rhs family protein
AM408_RS16940	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AM408_RS16945	COG4181	ATPase activity
AM408_RS16950	COG2755	lipolytic protein G-D-S-L family
AM408_RS16955	COG0300	oxidoreductase activity
AM408_RS16960	COG3118	belongs to the thioredoxin family
AM408_RS16965	COG0390	transport system, permease component
AM408_RS16970	COG4619	ABC transporter
AM408_RS16975	COG0330	HflC and HflK could
AM408_RS16980	COG1585	Membrane protein implicated in regulation of membrane protease activity
AM408_RS16985	COG0789	Transcriptional regulator
AM408_RS16995	COG0531	amino acid
AM408_RS17000	COG2066	Belongs to the glutaminase family
AM408_RS17005	COG2217	Heavy metal translocating P-type atpase
AM408_RS17010	COG3093	addiction module antidote protein HigA
AM408_RS17015	COG3735	TraB family
AM408_RS17025	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AM408_RS17030	COG0737	Belongs to the 5'-nucleotidase family
AM408_RS17040	COG2223	nitrite transmembrane transporter activity
AM408_RS17045	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM408_RS17045	COG4651	solute:proton antiporter activity
AM408_RS17050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM408_RS17090	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AM408_RS17105	COG2832	Protein of unknown function (DUF454)
AM408_RS17110	COG3923	Primosomal replication protein n
AM408_RS17120	COG1196	nuclear chromosome segregation
AM408_RS17120	COG3264	Mechanosensitive ion channel
AM408_RS17135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM408_RS17140	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM408_RS17155	COG0110	maltose O-acetyltransferase activity
AM408_RS17165	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AM408_RS17170	COG5507	3-demethylubiquinone-9 3-methyltransferase
AM408_RS17180	COG3695	enzyme binding
AM408_RS17185	COG3126	Type III secretion system lipoprotein chaperone (YscW)
AM408_RS17190	COG1946	Acyl-CoA thioesterase
AM408_RS17195	COG0004	ammonium transporteR
AM408_RS17200	COG0347	Belongs to the P(II) protein family
AM408_RS17205	COG1132	(ABC) transporter
AM408_RS17210	COG1132	(ABC) transporter
AM408_RS17215	COG1522	sequence-specific DNA binding
AM408_RS17225	COG4533	DNA binding
AM408_RS17235	COG0824	Thioesterase
AM408_RS17240	COG1555	photosystem II stabilization
AM408_RS17245	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM408_RS17250	COG0776	regulation of translation
AM408_RS17255	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AM408_RS17280	COG0271	Belongs to the BolA IbaG family
AM408_RS17290	COG3056	Lipoprotein
AM408_RS17295	COG2223	nitrite transmembrane transporter activity
AM408_RS17300	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AM408_RS17305	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AM408_RS17310	COG1845	cytochrome c oxidase, subunit III
AM408_RS17315	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AM408_RS17325	COG2814	Major facilitator Superfamily
AM408_RS17335	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AM408_RS17340	COG0693	protein deglycase activity
AM408_RS17355	COG0142	geranyltranstransferase activity
AM408_RS17365	COG0667	Aldo Keto reductase
AM408_RS17370	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AM408_RS17375	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AM408_RS17390	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM408_RS17390	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM408_RS17400	COG4238	major outer membrane lipoprotein
AM408_RS17405	COG3248	Nucleoside-binding outer membrane protein
AM408_RS17410	COG1403	HNH endonuclease
AM408_RS17415	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AM408_RS17420	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AM408_RS17425	COG1862	Preprotein translocase
AM408_RS17445	COG0366	Alpha amylase catalytic
AM408_RS17450	COG1113	amino acid transport
AM408_RS17455	COG1114	Component of the transport system for branched-chain amino acids
AM408_RS17460	COG5002	protein histidine kinase activity
AM408_RS17465	COG0745	RESPONSE REGULATOR receiver
AM408_RS17470	COG0420	3'-5' exonuclease activity
AM408_RS17475	COG0419	ATPase involved in DNA repair
AM408_RS17480	COG2814	Major facilitator Superfamily
AM408_RS17485	COG1940	carbohydrate kinase activity
AM408_RS17510	COG4126	flavin adenine dinucleotide binding
AM408_RS17535	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AM408_RS17540	COG3706	GGDEF domain
AM408_RS17550	COG1785	Belongs to the alkaline phosphatase family
AM408_RS17565	COG1181	Belongs to the D-alanine--D-alanine ligase family
AM408_RS17585	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AM408_RS17595	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AM408_RS17600	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM408_RS17605	COG3468	outer membrane autotransporter barrel domain protein
AM408_RS17615	COG0113	porphobilinogen synthase activity
AM408_RS17620	COG2175	clavaminate synthase activity
AM408_RS17625	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM408_RS17635	COG4521	taurine ABC transporter
AM408_RS17655	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AM408_RS17660	COG1215	transferase activity, transferring glycosyl groups
AM408_RS17675	COG3547	Transposase (IS116 IS110 IS902 family)
AM408_RS17695	COG3122	Protein conserved in bacteria
AM408_RS17700	COG2814	Major facilitator Superfamily
AM408_RS17715	COG3971	2-oxopent-4-enoate hydratase activity
AM408_RS17735	COG1414	Transcriptional regulator
AM408_RS17740	COG1609	Transcriptional regulator
AM408_RS17750	COG3250	beta-galactosidase activity
AM408_RS17755	COG2223	nitrite transmembrane transporter activity
AM408_RS17760	COG0110	maltose O-acetyltransferase activity
AM408_RS17765	COG2807	transmembrane transport
AM408_RS17775	COG0288	reversible hydration of carbon dioxide
AM408_RS17780	COG0583	DNA-binding transcription factor activity
AM408_RS17785	COG0402	S-adenosylhomocysteine deaminase activity
AM408_RS17790	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AM408_RS17795	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AM408_RS17800	COG2079	MmgE PrpD family protein
AM408_RS17805	COG0372	Belongs to the citrate synthase family
AM408_RS17810	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AM408_RS17815	COG3829	transcription factor binding
AM408_RS17825	COG1280	lysine exporter protein (LysE YggA)
AM408_RS17840	COG1064	alcohol dehydrogenase
AM408_RS17845	COG0402	S-adenosylhomocysteine deaminase activity
AM408_RS17850	COG0549	Belongs to the carbamate kinase family
AM408_RS17860	COG1304	FMN binding
AM408_RS17865	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AM408_RS17875	COG0666	response to abiotic stimulus
AM408_RS17890	COG0583	DNA-binding transcription factor activity
AM408_RS17895	COG2771	luxR family
AM408_RS17895	COG2200	EAL domain
AM408_RS17910	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM408_RS17950	COG1556	Lactate utilization protein
AM408_RS17955	COG1139	Iron-sulfur cluster binding protein
AM408_RS17960	COG0247	lactate metabolic process
AM408_RS17965	COG2207	Transcriptional regulator
AM408_RS17970	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM408_RS17980	COG3059	membrane
AM408_RS17985	COG3708	Transcriptional regulator
AM408_RS17985	COG2207	Transcriptional regulator
AM408_RS17990	COG1388	LysM domain
AM408_RS18045	COG3188	usher protein
AM408_RS18055	COG3121	Chaperone
AM408_RS18060	COG0727	PFAM Uncharacterised protein family (UPF0153)
AM408_RS18070	COG3477	response to acidic pH
AM408_RS18080	COG2080	2 iron, 2 sulfur cluster binding
AM408_RS18085	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AM408_RS18090	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AM408_RS18095	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AM408_RS18100	COG0583	DNA-binding transcription factor activity
AM408_RS18125	COG2003	Belongs to the UPF0758 family
AM408_RS18155	COG2020	methyltransferase activity
AM408_RS18290	COG3344	reverse transcriptase
AM408_RS18370	COG3811	Belongs to the UPF0386 family
AM408_RS18425	COG0582	viral genome integration into host DNA
AM408_RS18470	COG5301	cellulose 1,4-beta-cellobiosidase activity
AM408_RS18545	COG0740	serine-type endopeptidase activity
AM408_RS18585	COG3772	lysozyme
AM408_RS18620	COG1403	HNH endonuclease
AM408_RS18630	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
AM408_RS18640	COG4725	Belongs to the MT-A70-like family
AM408_RS18650	COG1846	Transcriptional regulator
AM408_RS18695	COG5532	Uncharacterized conserved protein (DUF2303)
AM408_RS18700	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AM408_RS18720	COG0582	viral genome integration into host DNA
AM408_RS18740	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AM408_RS18760	COG2195	Cleaves the N-terminal amino acid of tripeptides
AM408_RS18765	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AM408_RS18770	COG1690	Belongs to the RtcB family
AM408_RS18780	COG0454	-acetyltransferase
AM408_RS18790	COG2161	toxin-antitoxin pair type II binding
AM408_RS18810	COG1943	Transposase
AM408_RS18815	COG0791	NLP P60 protein
AM408_RS18820	COG3077	Addiction module antitoxin, RelB DinJ family
AM408_RS18825	COG3041	Addiction module toxin RelE StbE family
AM408_RS18830	COG3034	peptidoglycan biosynthetic process
AM408_RS18835	COG0121	glutamine amidotransferase
AM408_RS18845	COG1960	acyl-CoA dehydrogenase activity
AM408_RS18855	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM408_RS18860	COG5433	transposase activity
AM408_RS18870	COG3209	COG3209 Rhs family protein
AM408_RS18965	COG3157	Type VI secretion system effector, Hcp
AM408_RS18970	COG4104	PAAR repeat-containing protein
AM408_RS18990	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM408_RS19000	COG2226	methyltransferase
AM408_RS19010	COG0741	lytic transglycosylase activity
AM408_RS19010	COG1388	LysM domain
AM408_RS19015	COG2226	methyltransferase
AM408_RS19025	COG0583	DNA-binding transcription factor activity
AM408_RS19030	COG0656	L-ascorbic acid biosynthetic process
AM408_RS19065	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AM408_RS19070	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AM408_RS19075	COG2011	ABC-type metal ion transport system permease component
AM408_RS19080	COG1464	Belongs to the NlpA lipoprotein family
AM408_RS19090	COG1720	tRNA m6t6A37 methyltransferase activity
AM408_RS19100	COG0791	NLP P60 protein
AM408_RS19105	COG3015	lipoprotein NlpE involved in copper resistance
AM408_RS19110	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AM408_RS19115	COG4681	YaeQ
AM408_RS19125	COG4568	rho-dependent transcription termination
AM408_RS19130	COG0037	tRNA processing
AM408_RS19135	COG0346	lactoylglutathione lyase activity
AM408_RS19140	COG1982	Orn Lys Arg decarboxylase major
AM408_RS19150	COG0587	DNA-directed DNA polymerase activity
AM408_RS19175	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM408_RS19180	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AM408_RS19190	COG0750	zinc metalloprotease
AM408_RS19195	COG0575	Belongs to the CDS family
AM408_RS19200	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AM408_RS19205	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AM408_RS19240	COG0024	Methionine aminopeptidase
AM408_RS19255	COG1408	metallophosphoesterase
AM408_RS19265	COG3835	regulator
AM408_RS19270	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM408_RS19290	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AM408_RS19295	COG2860	membrane
AM408_RS19315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM408_RS19320	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AM408_RS19325	COG1120	ATPase activity
AM408_RS19330	COG4774	siderophore transport
AM408_RS19335	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AM408_RS19345	COG1643	Atp-dependent helicase
AM408_RS19350	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AM408_RS19360	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AM408_RS19370	COG0617	tRNA 3'-terminal CCA addition
AM408_RS19375	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AM408_RS19380	COG3539	Fimbrial protein
AM408_RS19385	COG3121	Chaperone
AM408_RS19390	COG3188	usher protein
AM408_RS19395	COG3539	Fimbrial protein
AM408_RS19400	COG3539	Fimbrial protein
AM408_RS19405	COG3539	Fimbrial protein
AM408_RS19410	COG3539	Fimbrial protein
AM408_RS19425	COG5464	transposase or invertase
AM408_RS19445	COG0726	polysaccharide deacetylase
AM408_RS19450	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM408_RS19455	COG0842	Transport permease protein
AM408_RS19460	COG1131	(ABC) transporter
AM408_RS19465	COG0288	reversible hydration of carbon dioxide
AM408_RS19470	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AM408_RS19475	COG4993	Dehydrogenase
AM408_RS19480	COG2132	Multicopper oxidase
AM408_RS19505	COG1049	propionate catabolic process, 2-methylcitrate cycle
AM408_RS19515	COG3064	Membrane
AM408_RS19520	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM408_RS19525	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM408_RS19530	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AM408_RS19540	COG2186	Transcriptional regulator
AM408_RS19545	COG1113	amino acid transport
AM408_RS19550	COG3725	Membrane protein required for beta-lactamase induction
AM408_RS19555	COG3023	N-Acetylmuramoyl-L-alanine amidase
AM408_RS19560	COG0157	Belongs to the NadC ModD family
AM408_RS19570	COG4969	Belongs to the N-Me-Phe pilin family
AM408_RS19575	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AM408_RS19580	COG1459	type II secretion system
AM408_RS19590	COG0237	dephospho-CoA kinase activity
AM408_RS19605	COG0494	nUDIX hydrolase
AM408_RS19625	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AM408_RS19630	COG0849	cell division
AM408_RS19635	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AM408_RS19640	COG1181	Belongs to the D-alanine--D-alanine ligase family
AM408_RS19655	COG0772	Belongs to the SEDS family
AM408_RS19670	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AM408_RS19675	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AM408_RS19680	COG0768	penicillin binding
AM408_RS19685	COG3116	cell division
AM408_RS19695	COG2001	Belongs to the MraZ family
AM408_RS19705	COG1609	Transcriptional regulator
AM408_RS19715	COG0440	acetolactate synthase activity
AM408_RS19720	COG0028	Belongs to the TPP enzyme family
AM408_RS19725	COG0583	DNA-binding transcription factor activity
AM408_RS19740	COG0473	3-isopropylmalate dehydrogenase activity
AM408_RS19755	COG2814	Major facilitator Superfamily
AM408_RS19765	COG4533	DNA binding
AM408_RS19770	COG4143	(ABC) transporter
AM408_RS19775	COG1178	ABC-type Fe3 transport system permease component
AM408_RS19780	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
AM408_RS19785	COG0586	Pfam SNARE associated Golgi protein
AM408_RS19790	COG4977	sequence-specific DNA binding
AM408_RS19800	COG1069	ribulokinase activity
AM408_RS19805	COG2160	L-arabinose isomerase activity
AM408_RS19810	COG0235	Class ii aldolase
AM408_RS19815	COG0417	DNA replication proofreading
AM408_RS19825	COG0564	pseudouridine synthase activity
AM408_RS19830	COG1357	PFAM Pentapeptide repeats (8 copies)
AM408_RS19835	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AM408_RS19840	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AM408_RS19845	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM408_RS19870	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AM408_RS19885	COG2271	Major facilitator Superfamily
AM408_RS19890	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AM408_RS19895	COG0644	oxidoreductase
AM408_RS19950	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AM408_RS19955	COG0505	Belongs to the CarA family
AM408_RS19980	COG1047	Peptidyl-prolyl cis-trans
AM408_RS19995	COG0196	riboflavin kinase activity
AM408_RS20025	COG0583	DNA-binding transcription factor activity
AM408_RS20045	COG3385	transposase activity
AM408_RS20065	COG4735	regulation of single-species biofilm formation
AM408_RS20070	COG1584	GPR1 FUN34 yaaH family protein
AM408_RS20075	COG0521	Mo-molybdopterin cofactor biosynthetic process
AM408_RS20080	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM408_RS20085	COG1115	amino acid carrier protein
AM408_RS20100	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AM408_RS20110	COG0527	aspartate kinase activity
AM408_RS20110	COG0460	homoserine dehydrogenase
AM408_RS20120	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AM408_RS20130	COG0745	RESPONSE REGULATOR receiver
AM408_RS20135	COG4452	Inner membrane protein CreD
AM408_RS20140	COG2205	protein histidine kinase activity
AM408_RS20145	COG0745	RESPONSE REGULATOR receiver
AM408_RS20150	COG3045	CreA protein
AM408_RS20155	COG2207	Transcriptional regulator
AM408_RS20155	COG3708	Transcriptional regulator
AM408_RS20175	COG0741	lytic transglycosylase activity
AM408_RS20185	COG0488	(ABC) transporter
AM408_RS20190	COG3172	ATPase kinase involved in NAD metabolism
AM408_RS20190	COG1056	cytidyltransferase-related domain
AM408_RS20195	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AM408_RS20200	COG0560	Phosphoserine phosphatase
AM408_RS20205	COG3726	membrane protein affecting hemolysin expression
AM408_RS20235	COG1328	CTP reductase activity
AM408_RS20240	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM408_RS20245	COG0084	hydrolase, TatD family'
AM408_RS20250	COG4667	esterase of the alpha-beta hydrolase superfamily
AM408_RS20260	COG2823	Periplasmic or secreted lipoprotein
AM408_RS20270	COG1011	Hydrolase
AM408_RS20275	COG0456	acetyltransferase
AM408_RS20280	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
AM408_RS20310	COG4114	ferric iron reductase
AM408_RS20315	COG2197	response regulator
AM408_RS20320	COG2197	response regulator
AM408_RS20325	COG2966	Psort location CytoplasmicMembrane, score
AM408_RS20340	COG1484	DNA-dependent DNA replication
AM408_RS20355	COG1063	alcohol dehydrogenase
AM408_RS20360	COG1802	Transcriptional regulator
AM408_RS20365	COG2271	Major facilitator Superfamily
AM408_RS20370	COG0840	transmembrane signaling receptor activity
AM408_RS20380	COG1966	Carbon starvation protein
AM408_RS20385	COG2879	small protein
AM408_RS20390	COG0523	cobalamin synthesis protein
AM408_RS20410	COG2814	Major facilitator Superfamily
AM408_RS20415	COG2733	membrane
AM408_RS20420	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
AM408_RS20425	COG1924	4 iron, 4 sulfur cluster binding
AM408_RS20440	COG0477	Major facilitator Superfamily
AM408_RS20450	COG3366	ferrous iron transmembrane transporter activity
AM408_RS20455	COG0700	Nucleoside recognition
AM408_RS20460	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AM408_RS20465	COG0583	DNA-binding transcription factor activity
AM408_RS20485	COG2186	Transcriptional regulator
AM408_RS20495	COG0246	Mannitol dehydrogenase
AM408_RS20510	COG2610	gluconate transmembrane transporter activity
AM408_RS20515	COG3539	Fimbrial protein
AM408_RS20535	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AM408_RS20565	COG3436	PFAM IS66 Orf2 family protein
AM408_RS20570	COG4372	Transposase
AM408_RS20605	COG1595	DNA-templated transcription, initiation
AM408_RS20610	COG3712	iron ion homeostasis
AM408_RS20615	COG4772	TonB-dependent receptor
AM408_RS20620	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AM408_RS20625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM408_RS20630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM408_RS20635	COG1120	ATPase activity
AM408_RS20640	COG2085	NADP oxidoreductase coenzyme F420-dependent
AM408_RS20650	COG3344	reverse transcriptase
AM408_RS20670	COG0726	polysaccharide deacetylase
AM408_RS20675	COG0297	glycogen (starch) synthase activity
AM408_RS20680	COG2990	Protein conserved in bacteria
AM408_RS20695	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM408_RS20715	COG1309	transcriptional regulator
AM408_RS20740	COG3344	reverse transcriptase
AM408_RS20820	COG0582	viral genome integration into host DNA
AM408_RS20830	COG1064	alcohol dehydrogenase
AM408_RS20835	COG0433	COG0433 Predicted ATPase
AM408_RS20840	COG0795	lipopolysaccharide-transporting ATPase activity
AM408_RS20845	COG0795	lipopolysaccharide-transporting ATPase activity
AM408_RS20855	COG2927	DNA polymerase III (CHI subunit)
AM408_RS20870	COG0456	acetyltransferase
AM408_RS20875	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
AM408_RS20895	COG2731	YhcH YjgK YiaL family protein
AM408_RS20900	COG1309	transcriptional regulator
AM408_RS20905	COG1028	Short-chain dehydrogenase reductase Sdr
AM408_RS20910	COG0251	oxidation-reduction process
AM408_RS20935	COG0251	oxidation-reduction process
AM408_RS20940	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AM408_RS20945	COG1609	Transcriptional regulator
AM408_RS20950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM408_RS20950	COG1263	PTS System
AM408_RS20955	COG0366	Alpha amylase catalytic
AM408_RS20960	COG1328	CTP reductase activity
AM408_RS20965	COG0602	queuosine metabolic process
AM408_RS20970	COG3783	Cytochrome b(562)
AM408_RS20975	COG0312	modulator of DNA gyrase
AM408_RS20985	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AM408_RS20995	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM408_RS21000	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM408_RS21005	COG1129	ABC transporter
AM408_RS21010	COG1879	ABC-type sugar transport system periplasmic component
AM408_RS21015	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AM408_RS21020	COG2337	Toxic component of a toxin-antitoxin (TA) module
AM408_RS21025	COG2336	PFAM SpoVT AbrB
AM408_RS21030	COG2105	PFAM AIG2 family protein
AM408_RS21035	COG2911	Protein conserved in bacteria
AM408_RS21040	COG0729	surface antigen
AM408_RS21055	COG1253	flavin adenine dinucleotide binding
AM408_RS21065	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AM408_RS21080	COG1218	3'(2'),5'-bisphosphate nucleotidase
AM408_RS21085	COG0737	Belongs to the 5'-nucleotidase family
AM408_RS21090	COG1733	regulation of RNA biosynthetic process
AM408_RS21095	COG0702	epimerase
AM408_RS21100	COG0697	spore germination
AM408_RS21110	COG1113	amino acid transport
AM408_RS21115	COG0545	Peptidyl-prolyl cis-trans isomerase
AM408_RS21125	COG3061	Opacity-associated protein A
AM408_RS21130	COG1309	transcriptional regulator
AM408_RS21135	COG0675	Transposase, IS605 OrfB family
AM408_RS21160	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AM408_RS21180	COG3477	response to acidic pH
AM408_RS21185	COG0235	Class ii aldolase
AM408_RS21200	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM408_RS21205	COG3414	Phosphotransferase system galactitol-specific IIB component
AM408_RS21210	COG3037	sugar-specific permease SgaT UlaA
AM408_RS21225	COG1073	alpha beta
AM408_RS21230	COG3650	response to hydrogen peroxide
AM408_RS21245	COG1960	acyl-CoA dehydrogenase activity
AM408_RS21250	COG0754	glutathionylspermidine amidase activity
AM408_RS21255	COG5463	Belongs to the UPF0441 family
AM408_RS21260	COG3766	membrane
AM408_RS21280	COG2721	sulfolactate sulfo-lyase activity
AM408_RS21285	COG2271	Major facilitator Superfamily
AM408_RS21290	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM408_RS21295	COG1414	Transcriptional regulator
AM408_RS21300	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM408_RS21305	COG0557	exoribonuclease II activity
AM408_RS21320	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AM408_RS21325	COG0330	HflC and HflK could
AM408_RS21330	COG0330	HflC and HflK could
AM408_RS21335	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AM408_RS21355	COG0860	N-Acetylmuramoyl-L-alanine amidase
AM408_RS21360	COG0802	atpase or kinase
AM408_RS21365	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AM408_RS21365	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AM408_RS21370	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AM408_RS21410	COG1511	domain protein
AM408_RS21410	COG3264	Mechanosensitive ion channel
AM408_RS21425	COG0531	amino acid
AM408_RS21435	COG1053	succinate dehydrogenase
AM408_RS21440	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AM408_RS21455	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AM408_RS21460	COG3040	lipid binding
AM408_RS21465	COG2076	Multidrug Resistance protein
AM408_RS21470	COG5510	response to toxic substance
AM408_RS21475	COG5510	response to toxic substance
AM408_RS21485	COG1509	lysine 2,3-aminomutase activity
AM408_RS21510	COG0531	amino acid
AM408_RS21515	COG3030	protein affecting phage T7 exclusion by the F plasmid
AM408_RS21520	COG1027	Aspartate ammonia-lyase
AM408_RS21525	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AM408_RS21535	COG4232	protein-disulfide reductase activity
AM408_RS21540	COG1309	transcriptional regulator
AM408_RS21555	COG3710	Transcriptional regulator
AM408_RS21560	COG0531	amino acid
AM408_RS21565	COG1982	Orn Lys Arg decarboxylase major
AM408_RS21570	COG3104	oligopeptide transport
AM408_RS21575	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AM408_RS21595	COG2388	GCN5-related N-acetyl-transferase
AM408_RS21600	COG3592	Divergent 4Fe-4S mono-cluster
AM408_RS21605	COG3290	protein histidine kinase activity
AM408_RS21610	COG4565	transcriptional regulatory protein
AM408_RS21620	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AM408_RS21625	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AM408_RS21625	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AM408_RS21630	COG3647	Membrane
AM408_RS21635	COG2211	Major facilitator Superfamily
AM408_RS21640	COG1486	melibiose metabolic process
AM408_RS21645	COG2169	Transcriptional regulator
AM408_RS21650	COG1982	Orn Lys Arg decarboxylase major
AM408_RS21655	COG2207	Transcriptional regulator
AM408_RS21660	COG0531	amino acid
AM408_RS21665	COG2194	sulfuric ester hydrolase activity
AM408_RS21670	COG0745	RESPONSE REGULATOR receiver
AM408_RS21675	COG0642	Histidine kinase
AM408_RS21685	COG0477	Major facilitator Superfamily
AM408_RS21705	COG2824	Alkylphosphonate utilization operon protein PhnA
AM408_RS21710	COG2764	glyoxalase bleomycin resistance protein dioxygenase
AM408_RS21715	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AM408_RS21720	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AM408_RS21730	COG2188	Transcriptional regulator
AM408_RS21735	COG3624	Phosphonate C-P lyase system protein PhnG
AM408_RS21740	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AM408_RS21745	COG3626	phosphonate metabolism
AM408_RS21750	COG3627	carbon phosphorus lyase activity
AM408_RS21755	COG4107	phosphonate C-P lyase system protein PhnK
AM408_RS21760	COG4778	phosphonate C-P lyase system protein PhnL
AM408_RS21765	COG3454	Phosphonate metabolism
AM408_RS21770	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AM408_RS21775	COG0456	acetyltransferase
AM408_RS21780	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AM408_RS21790	COG0698	ribose 5-phosphate isomerase
AM408_RS21800	COG1737	Transcriptional regulator
AM408_RS21805	COG1879	ABC-type sugar transport system periplasmic component
AM408_RS21810	COG1129	ABC transporter
AM408_RS21815	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM408_RS21820	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AM408_RS21825	COG1940	carbohydrate kinase activity
AM408_RS21830	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AM408_RS21840	COG1566	PFAM secretion protein HlyD family protein
AM408_RS21845	COG1289	transmembrane transporter activity
AM408_RS21850	COG1538	Outer membrane efflux protein
AM408_RS21860	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AM408_RS21865	COG1301	dicarboxylic acid transport
AM408_RS21875	COG4235	cytochrome complex assembly
AM408_RS21880	COG3088	subunit of a heme lyase
AM408_RS21885	COG1138	Cytochrome C-type biogenesis protein
AM408_RS21890	COG3301	Polysulphide reductase, NrfD
AM408_RS21895	COG0437	4 iron, 4 sulfur cluster binding
AM408_RS21900	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
AM408_RS21915	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AM408_RS21920	COG3162	membrane
AM408_RS21930	COG1357	PFAM Pentapeptide repeats (8 copies)
AM408_RS21935	COG0025	NhaP-type Na H and K H
AM408_RS21940	COG2252	PERMEase
AM408_RS21960	COG0789	Transcriptional regulator
AM408_RS21965	COG2207	Transcriptional regulator
AM408_RS21970	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AM408_RS22020	COG0629	single-stranded DNA binding
AM408_RS22025	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AM408_RS22030	COG2315	Protein conserved in bacteria
AM408_RS22035	COG0432	Pfam Uncharacterised protein family UPF0047
AM408_RS22040	COG3700	Belongs to the class B bacterial acid phosphatase family
AM408_RS22055	COG1448	Aminotransferase
AM408_RS22060	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AM408_RS22065	COG0305	Participates in initiation and elongation during chromosome replication
AM408_RS22070	COG0604	alcohol dehydrogenase
AM408_RS22080	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM408_RS22095	COG0735	belongs to the Fur family
AM408_RS22100	COG3237	CsbD-like
AM408_RS22105	COG0534	Mate efflux family protein
AM408_RS22115	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AM408_RS22140	COG1357	PFAM Pentapeptide repeats (8 copies)
AM408_RS22160	COG3842	ATPase activity
AM408_RS22170	COG2182	Extracellular solute-binding protein
AM408_RS22175	COG1175	transmembrane transport
AM408_RS22180	COG3833	ABC-type maltose transport systems, permease component
AM408_RS22185	COG2814	Major facilitator Superfamily
AM408_RS22185	COG0477	Major facilitator Superfamily
AM408_RS22200	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM408_RS22235	COG0527	aspartate kinase activity
AM408_RS22245	COG1187	pseudouridine synthase activity
AM408_RS22255	COG1283	sodium-dependent phosphate transmembrane transporter activity
AM408_RS22260	COG1410	methionine synthase
AM408_RS22260	COG0646	methionine synthase
AM408_RS22265	COG1414	Transcriptional regulator
AM408_RS22280	COG2224	Isocitrate lyase
AM408_RS22285	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AM408_RS22295	COG0456	acetyltransferase
AM408_RS22335	COG0151	Belongs to the GarS family
AM408_RS22340	COG2204	response regulator
AM408_RS22345	COG4191	Histidine kinase
AM408_RS22355	COG3678	ATP-independent chaperone mediated protein folding
AM408_RS22370	COG3068	Protein conserved in bacteria
AM408_RS22405	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AM408_RS22410	COG2104	thiamine diphosphate biosynthetic process
AM408_RS22420	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AM408_RS22465	COG0250	Participates in transcription elongation, termination and antitermination
AM408_RS22470	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AM408_RS22515	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AM408_RS22515	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AM408_RS22520	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AM408_RS22550	COG4206	TonB-dependent receptor
AM408_RS22580	COG0583	DNA-binding transcription factor activity
AM408_RS22595	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AM408_RS22615	COG2194	sulfuric ester hydrolase activity
AM408_RS22620	COG2207	Transcriptional regulator
AM408_RS22625	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM408_RS22630	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM408_RS22635	COG1882	Formate acetyltransferase
AM408_RS22640	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM408_RS22645	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM408_RS22650	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM408_RS22650	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM408_RS22650	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM408_RS22655	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM408_RS22660	COG0371	Dehydrogenase
AM408_RS22665	COG3738	Protein conserved in bacteria
AM408_RS22670	COG0697	spore germination
AM408_RS22680	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AM408_RS22685	COG0460	homoserine dehydrogenase
AM408_RS22685	COG0527	aspartate kinase activity
AM408_RS22690	COG0626	cystathionine gamma-synthase activity
AM408_RS22700	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
AM408_RS22710	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AM408_RS22715	COG1609	Transcriptional regulator
AM408_RS22720	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AM408_RS22735	COG1575	Belongs to the MenA family. Type 1 subfamily
AM408_RS22750	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AM408_RS22760	COG1494	fructose-1,6-bisphosphatase
AM408_RS22765	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM408_RS22770	COG0589	response to stress
AM408_RS22775	COG3691	Protein conserved in bacteria
AM408_RS22780	COG3152	Membrane
AM408_RS22805	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AM408_RS22870	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AM408_RS22880	COG3436	PFAM IS66 Orf2 family protein
AM408_RS22895	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AM408_RS22905	COG1484	DNA-dependent DNA replication
AM408_RS22910	COG4584	PFAM Integrase catalytic
AM408_RS22955	COG4974	Belongs to the 'phage' integrase family
AM408_RS22960	COG3678	ATP-independent chaperone mediated protein folding
AM408_RS22965	COG0745	RESPONSE REGULATOR receiver
AM408_RS22970	COG2205	protein histidine kinase activity
AM408_RS22975	COG2258	MOSC domain
AM408_RS22990	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AM408_RS23030	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM408_RS23035	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM408_RS23035	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM408_RS23040	COG1363	Peptidase, m42
AM408_RS23045	COG3711	transcriptional antiterminator
AM408_RS23045	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM408_RS23065	COG3383	formate dehydrogenase (NAD+) activity
AM408_RS23065	COG0243	molybdopterin cofactor binding
AM408_RS23070	COG0243	molybdopterin cofactor binding
AM408_RS23070	COG3383	formate dehydrogenase (NAD+) activity
AM408_RS23075	COG0437	4 iron, 4 sulfur cluster binding
AM408_RS23080	COG2864	formate dehydrogenase
AM408_RS23090	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AM408_RS23095	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AM408_RS23100	COG0456	acetyltransferase
AM408_RS23115	COG1011	Hydrolase
AM408_RS23120	COG1349	DNA-binding transcription factor activity
AM408_RS23125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM408_RS23130	COG2084	Dehydrogenase
AM408_RS23135	COG3684	Belongs to the aldolase LacD family
AM408_RS23140	COG2942	2-epimerase
AM408_RS23145	COG2017	converts alpha-aldose to the beta-anomer
AM408_RS23150	COG1501	Belongs to the glycosyl hydrolase 31 family
AM408_RS23155	COG2211	Major facilitator Superfamily
AM408_RS23160	COG2211	Major facilitator Superfamily
AM408_RS23165	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AM408_RS23170	COG2271	Major facilitator Superfamily
AM408_RS23175	COG1082	Xylose isomerase domain protein TIM barrel
AM408_RS23180	COG2188	Transcriptional regulator
AM408_RS23185	COG1217	gtp-binding protein TYPA
AM408_RS23195	COG0174	glutamine synthetase
AM408_RS23200	COG3852	Histidine kinase
AM408_RS23205	COG2204	response regulator
AM408_RS23215	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AM408_RS23235	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AM408_RS23235	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AM408_RS23245	COG0204	Acyl-transferase
AM408_RS23250	COG5339	Protein conserved in bacteria
AM408_RS23255	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM408_RS23260	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AM408_RS23265	COG3084	Protein conserved in bacteria
AM408_RS23270	COG0746	molybdenum cofactor guanylyltransferase activity
AM408_RS23275	COG1763	Mo-molybdopterin cofactor biosynthetic process
AM408_RS23305	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
AM408_RS23310	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AM408_RS23315	COG1739	Uncharacterized protein family UPF0029
AM408_RS23330	COG0183	Belongs to the thiolase family
AM408_RS23335	COG0543	2 iron, 2 sulfur cluster binding
AM408_RS23340	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AM408_RS23345	COG0250	Participates in transcription elongation, termination and antitermination
AM408_RS23350	COG0084	hydrolase, TatD family'
AM408_RS23355	COG0805	protein transport
AM408_RS23360	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AM408_RS23365	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AM408_RS23375	COG3165	ubiquinone biosynthetic process from chorismate
AM408_RS23385	COG1322	Protein conserved in bacteria
AM408_RS23390	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
AM408_RS23395	COG0412	Dienelactone hydrolase
AM408_RS23405	COG0583	DNA-binding transcription factor activity
AM408_RS23410	COG0697	spore germination
AM408_RS23415	COG0561	phosphatase activity
AM408_RS23420	COG2267	carboxylic ester hydrolase activity
AM408_RS23425	COG1280	lysine exporter protein (LysE YggA)
AM408_RS23430	COG1280	lysine exporter protein (LysE YggA)
AM408_RS23435	COG0514	ATP-dependent DNA helicase (RecQ)
AM408_RS23440	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
AM408_RS23445	COG2050	protein possibly involved in aromatic compounds catabolism
AM408_RS23450	COG2962	Rard protein
AM408_RS23465	COG0598	Magnesium transport protein CorA
AM408_RS23470	COG3698	Phosphodiester glycosidase
AM408_RS23475	COG0210	DNA helicase
AM408_RS23480	COG1011	Hydrolase
AM408_RS23490	COG3159	Protein conserved in bacteria
AM408_RS23500	COG5567	small periplasmic lipoprotein
AM408_RS23515	COG3072	Adenylate cyclase
AM408_RS23530	COG1587	Uroporphyrinogen-III synthase
AM408_RS23535	COG2959	enzyme of heme biosynthesis
AM408_RS23540	COG3071	HemY protein
AM408_RS23545	COG3119	arylsulfatase activity
AM408_RS23550	COG0641	radical SAM
AM408_RS23575	COG1113	amino acid transport
AM408_RS23595	COG2244	polysaccharide biosynthetic process
AM408_RS23600	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AM408_RS23605	COG0456	acetyltransferase
AM408_RS23610	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AM408_RS23615	COG1088	dTDP-glucose 4,6-dehydratase activity
AM408_RS23620	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AM408_RS23625	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AM408_RS23630	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
AM408_RS23635	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AM408_RS23645	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AM408_RS23655	COG3118	belongs to the thioredoxin family
AM408_RS23675	COG0210	DNA helicase
AM408_RS23680	COG3692	DNA binding
AM408_RS23685	COG3692	DNA binding
AM408_RS23690	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM408_RS23700	COG0583	DNA-binding transcription factor activity
AM408_RS23705	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AM408_RS23715	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AM408_RS23720	COG3978	acetolactate synthase activity
AM408_RS23735	COG0606	chelatase, subunit chli
AM408_RS23740	COG3085	chromosome segregation
AM408_RS23780	COG2186	Transcriptional regulator
AM408_RS23785	COG0477	Major facilitator Superfamily
AM408_RS23790	COG1609	Transcriptional regulator
AM408_RS23795	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM408_RS23800	COG1879	ABC-type sugar transport system periplasmic component
AM408_RS23805	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM408_RS23810	COG1129	ABC transporter
AM408_RS23840	COG1522	sequence-specific DNA binding
AM408_RS23845	COG0716	FMN binding
AM408_RS23860	COG3312	ion transport
AM408_RS23910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AM408_RS23915	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AM408_RS23920	COG0573	inorganic phosphate transmembrane transporter activity
AM408_RS23925	COG0581	inorganic phosphate transmembrane transporter activity
AM408_RS23930	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AM408_RS23935	COG0704	Plays a role in the regulation of phosphate uptake
AM408_RS23940	COG3711	transcriptional antiterminator
AM408_RS23945	COG1263	PTS System
AM408_RS23945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM408_RS23945	COG2190	(PTS) system
AM408_RS23950	COG2723	6-phospho-beta-galactosidase activity
AM408_RS23970	COG0363	glucosamine-6-phosphate deaminase activity
AM408_RS23975	COG3196	Protein conserved in bacteria
AM408_RS23985	COG3436	PFAM IS66 Orf2 family protein
AM408_RS23995	COG3196	Protein conserved in bacteria
AM408_RS24005	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM408_RS24010	COG2252	PERMEase
AM408_RS24015	COG0431	NADPH-dependent FMN reductase
AM408_RS24020	COG2091	lysine biosynthetic process via aminoadipic acid
AM408_RS24035	COG0814	amino acid
AM408_RS24085	COG0592	DNA-directed DNA polymerase activity
AM408_RS24095	COG0187	DNA topoisomerase II activity
AM408_RS24100	COG3753	Protein conserved in bacteria
AM408_RS24105	COG0561	phosphatase activity
AM408_RS24115	COG2186	Transcriptional regulator
AM408_RS24120	COG3734	2-keto-3-deoxy-galactonokinase
AM408_RS24125	COG0800	Aldolase
AM408_RS24135	COG2271	Major facilitator Superfamily
AM408_RS24140	COG0644	oxidoreductase
AM408_RS24145	COG0823	Involved in the tonB-independent uptake of proteins
AM408_RS24150	COG5645	(Lipo)protein
AM408_RS24170	COG2188	Transcriptional regulator
AM408_RS24185	COG2207	Transcriptional regulator
AM408_RS24190	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AM408_RS24195	COG3119	arylsulfatase activity
AM408_RS24205	COG2149	membrane
AM408_RS24215	COG0641	radical SAM
AM408_RS24220	COG2814	Major facilitator Superfamily
AM408_RS24260	COG0028	Belongs to the TPP enzyme family
AM408_RS24265	COG0440	acetolactate synthase activity
AM408_RS24270	COG2197	response regulator
AM408_RS24275	COG3851	Histidine kinase
AM408_RS24280	COG2271	Major facilitator Superfamily
AM408_RS24285	COG2271	Major facilitator Superfamily
AM408_RS24295	COG2252	PERMEase
AM408_RS24325	COG1464	Belongs to the NlpA lipoprotein family
AM408_RS24330	COG0697	spore germination
AM408_RS24335	COG2814	Major facilitator Superfamily
AM408_RS24350	COG2211	Major facilitator Superfamily
AM408_RS24355	COG1501	Belongs to the glycosyl hydrolase 31 family
AM408_RS24360	COG2982	Protein involved in outer membrane biogenesis
AM408_RS24365	COG2233	PERMEase
AM408_RS24370	COG0786	glutamate:sodium symporter activity
AM408_RS24375	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AM408_RS24380	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM408_RS24385	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM408_RS24395	COG0194	GDP metabolic process
AM408_RS24405	COG2860	membrane
AM408_RS24410	COG3645	SOS response
AM408_RS24420	COG1561	YicC-like family, N-terminal region
AM408_RS24450	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AM408_RS24480	COG1519	Transferase
AM408_RS24485	COG0859	PFAM glycosyl transferase family 9
AM408_RS24490	COG0438	transferase activity, transferring glycosyl groups
AM408_RS24495	COG0515	serine threonine protein kinase
AM408_RS24500	COG1442	glycosyl transferase family 8
AM408_RS24505	COG0438	transferase activity, transferring glycosyl groups
AM408_RS24510	COG1442	glycosyl transferase family 8
AM408_RS24515	COG1442	glycosyl transferase family 8
AM408_RS24520	COG3642	lipopolysaccharide core region biosynthetic process
AM408_RS24540	COG0859	PFAM glycosyl transferase family 9
AM408_RS24545	COG0859	PFAM glycosyl transferase family 9
AM408_RS24555	COG0156	8-amino-7-oxononanoate synthase activity
AM408_RS24565	COG1216	Glycosyl transferase, family 2
AM408_RS24570	COG2861	carbohydrate metabolic process
AM408_RS24575	COG4942	peptidase
AM408_RS24590	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AM408_RS24595	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM408_RS24610	COG1045	serine acetyltransferase
AM408_RS24615	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AM408_RS24625	COG2186	Transcriptional regulator
AM408_RS24630	COG1620	l-lactate permease
AM408_RS24650	COG3722	fumarate hydratase activity
AM408_RS24660	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM408_RS24660	COG2213	PTS system mannitol-specific
AM408_RS24670	COG1566	PFAM secretion protein HlyD family protein
AM408_RS24695	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AM408_RS24700	COG3209	COG3209 Rhs family protein
AM408_RS24715	COG3209	COG3209 Rhs family protein
AM408_RS24720	COG1413	lyase activity
AM408_RS24725	COG3209	COG3209 Rhs family protein
AM408_RS24730	COG0625	glutathione transferase activity
AM408_RS24740	COG3276	selenocysteine insertion sequence binding
AM408_RS24745	COG1454	alcohol dehydrogenase
AM408_RS24750	COG1012	belongs to the aldehyde dehydrogenase family
AM408_RS24765	COG1566	PFAM secretion protein HlyD family protein
AM408_RS24770	COG0583	DNA-binding transcription factor activity
AM408_RS24775	COG3713	MltA-interacting MipA family protein
AM408_RS24785	COG0235	Class ii aldolase
AM408_RS24790	COG3623	hexulose-6-phosphate isomerase
AM408_RS24795	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AM408_RS24800	COG1070	Carbohydrate kinase
AM408_RS24805	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AM408_RS24810	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AM408_RS24815	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AM408_RS24820	COG2731	YhcH YjgK YiaL family protein
AM408_RS24830	COG1414	Transcriptional regulator
AM408_RS24835	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM408_RS24840	COG3977	Valine--pyruvate aminotransferase
AM408_RS24845	COG0366	Alpha amylase catalytic
AM408_RS24850	COG2992	FlgJ-related protein
AM408_RS24855	COG2207	Transcriptional regulator
AM408_RS24855	COG1609	Transcriptional regulator
AM408_RS24860	COG4214	carbohydrate transport
AM408_RS24865	COG1129	ABC transporter
AM408_RS24870	COG4213	ABC transporter substrate-binding protein
AM408_RS24880	COG1070	Carbohydrate kinase
AM408_RS24885	COG4682	membrane
AM408_RS24890	COG4682	membrane
AM408_RS24895	COG3274	enterobacterial common antigen metabolic process
AM408_RS24925	COG1278	Cold shock
AM408_RS24930	COG2944	sequence-specific DNA binding
AM408_RS24945	COG2885	chlorophyll binding
AM408_RS24950	COG0243	molybdopterin cofactor binding
AM408_RS24955	COG0456	acetyltransferase
AM408_RS24960	COG2818	Glycosylase
AM408_RS24965	COG5571	outer membrane autotransporter
AM408_RS24975	COG2223	nitrite transmembrane transporter activity
AM408_RS24980	COG2194	sulfuric ester hydrolase activity
AM408_RS24995	COG0747	negative chemotaxis
AM408_RS25005	COG0601	transmembrane transport
AM408_RS25010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM408_RS25015	COG0444	Belongs to the ABC transporter superfamily
AM408_RS25020	COG4608	Belongs to the ABC transporter superfamily
AM408_RS25025	COG0814	amino acid
AM408_RS25045	COG2194	sulfuric ester hydrolase activity
AM408_RS25075	COG1215	transferase activity, transferring glycosyl groups
AM408_RS25080	COG1215	transferase activity, transferring glycosyl groups
AM408_RS25085	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AM408_RS25090	COG3118	belongs to the thioredoxin family
AM408_RS25090	COG0457	Tetratricopeptide repeat
AM408_RS25095	COG2200	EAL domain
AM408_RS25095	COG2199	diguanylate cyclase activity
AM408_RS25115	COG0612	Peptidase, M16
AM408_RS25120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM408_RS25130	COG2200	EAL domain
AM408_RS25135	COG2982	Protein involved in outer membrane biogenesis
AM408_RS25140	COG0477	Major facilitator Superfamily
AM408_RS25145	COG1295	ribonuclease BN
AM408_RS25150	COG0583	DNA-binding transcription factor activity
AM408_RS25155	COG2197	response regulator
AM408_RS25165	COG1858	cytochrome C peroxidase
AM408_RS25170	COG0076	glutamate decarboxylase activity
AM408_RS25175	COG2207	Transcriptional regulator
AM408_RS25180	COG2207	Transcriptional regulator
AM408_RS25190	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM408_RS25195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM408_RS25205	COG2771	luxR family
AM408_RS25210	COG3247	response to pH
AM408_RS25225	COG1285	pathogenesis
AM408_RS25230	COG2197	response regulator
AM408_RS25240	COG3065	identical protein binding
AM408_RS25250	COG1393	Belongs to the ArsC family
AM408_RS25255	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AM408_RS25260	COG0640	Transcriptional regulator
AM408_RS25275	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM408_RS25280	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AM408_RS25285	COG0339	signal peptide processing
AM408_RS25295	COG3104	oligopeptide transport
AM408_RS25305	COG0589	response to stress
AM408_RS25315	COG0306	phosphate transporter
AM408_RS25320	COG2081	HI0933 family
AM408_RS25345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM408_RS25350	COG1129	ABC transporter
AM408_RS25350	COG0842	Transport permease protein
AM408_RS25355	COG0842	Transport permease protein
AM408_RS25360	COG5433	transposase activity
AM408_RS25365	COG1413	lyase activity
AM408_RS25375	COG3209	COG3209 Rhs family protein
AM408_RS25385	COG1124	(ABC) transporter
AM408_RS25390	COG0444	Belongs to the ABC transporter superfamily
AM408_RS25395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM408_RS25400	COG0601	transmembrane transport
AM408_RS25405	COG0747	negative chemotaxis
AM408_RS25410	COG2091	lysine biosynthetic process via aminoadipic acid
AM408_RS25415	COG0628	permease
AM408_RS25420	COG0477	Major facilitator Superfamily
AM408_RS25430	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AM408_RS25440	COG2217	Heavy metal translocating P-type atpase
AM408_RS25445	COG3714	YhhN family
AM408_RS25455	COG3776	membrane
AM408_RS25460	COG0742	ribosomal rna small subunit methyltransferase
AM408_RS25465	COG0552	protein localization to endoplasmic reticulum
AM408_RS25470	COG2884	Cell division ATP-binding protein ftsE
AM408_RS25475	COG2177	Part of the ABC transporter FtsEX involved in
AM408_RS25480	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM408_RS25485	COG0683	leucine binding
AM408_RS25490	COG0456	acetyltransferase
AM408_RS25500	COG0683	leucine binding
AM408_RS25505	COG0559	Belongs to the binding-protein-dependent transport system permease family
AM408_RS25510	COG4177	L-phenylalanine transmembrane transporter activity
AM408_RS25515	COG0411	ABC transporter
AM408_RS25520	COG0410	ABC transporter
AM408_RS25525	COG1653	transport
AM408_RS25530	COG1175	transmembrane transport
AM408_RS25535	COG0395	ABC-type sugar transport system, permease component
AM408_RS25540	COG3842	ATPase activity
AM408_RS25545	COG0584	glycerophosphoryl diester phosphodiesterase
AM408_RS25555	COG0405	Gamma-glutamyltransferase
AM408_RS25575	COG3157	Type VI secretion system effector, Hcp
AM408_RS25580	COG1247	-acetyltransferase
AM408_RS25590	COG0673	inositol 2-dehydrogenase activity
AM408_RS25595	COG1741	Belongs to the pirin family
AM408_RS25600	COG1609	Transcriptional regulator
AM408_RS25605	COG3265	gluconokinase activity
AM408_RS25610	COG2610	gluconate transmembrane transporter activity
AM408_RS25615	COG2095	MarC family integral membrane protein
AM408_RS25620	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AM408_RS25645	COG0058	SHG alpha-glucan phosphorylase activity
AM408_RS25650	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AM408_RS25660	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AM408_RS25675	COG1349	DNA-binding transcription factor activity
AM408_RS25680	COG4650	regulator
AM408_RS25685	COG1690	Belongs to the RtcB family
AM408_RS25795	COG0459	protein refolding
AM408_RS25830	COG3173	Aminoglycoside phosphotransferase
AM408_RS26085	COG4372	Transposase
AM408_RS26090	COG3436	PFAM IS66 Orf2 family protein
AM408_RS26265	COG4584	PFAM Integrase catalytic
AM408_RS26270	COG1484	DNA-dependent DNA replication