locus-tag	class	description
CS032_RS00120	COG1192	Involved in chromosome partitioning
CS032_RS00210	COG0640	Transcriptional regulator
CS032_RS00225	COG0786	glutamate:sodium symporter activity
CS032_RS00295	COG1585	Membrane protein implicated in regulation of membrane protease activity
CS032_RS00300	COG2268	Band 7 protein
CS032_RS00340	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CS032_RS00355	COG0741	lytic transglycosylase activity
CS032_RS00845	COG3121	Chaperone
CS032_RS00905	COG0577	efflux transmembrane transporter activity
CS032_RS00905	COG1136	(ABC) transporter
CS032_RS00975	COG3436	PFAM IS66 Orf2 family protein
CS032_RS00980	COG4372	Transposase
CS032_RS01035	COG0438	transferase activity, transferring glycosyl groups
CS032_RS01055	COG3436	PFAM IS66 Orf2 family protein
CS032_RS01060	COG4372	Transposase
CS032_RS01125	COG4584	PFAM Integrase catalytic
CS032_RS01195	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CS032_RS01245	COG2801	Transposase and inactivated derivatives
CS032_RS01320	COG4372	Transposase
CS032_RS01325	COG3436	PFAM IS66 Orf2 family protein
CS032_RS01350	COG3436	PFAM IS66 Orf2 family protein
CS032_RS01355	COG4372	Transposase
CS032_RS01410	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CS032_RS01420	COG0252	asparaginase activity
CS032_RS01430	COG3171	Protein conserved in bacteria
CS032_RS01445	COG1194	a g-specific adenine glycosylase
CS032_RS01460	COG2211	Major facilitator Superfamily
CS032_RS01465	COG1982	Orn Lys Arg decarboxylase major
CS032_RS01475	COG1811	Na channel or pump
CS032_RS01485	COG0582	viral genome integration into host DNA
CS032_RS01500	COG3436	PFAM IS66 Orf2 family protein
CS032_RS01510	COG4372	Transposase
CS032_RS01515	COG3436	PFAM IS66 Orf2 family protein
CS032_RS01585	COG3436	PFAM IS66 Orf2 family protein
CS032_RS01635	COG3468	outer membrane autotransporter barrel domain protein
CS032_RS01660	COG2003	Belongs to the UPF0758 family
CS032_RS01715	COG1091	dTDP-4-dehydrorhamnose reductase activity
CS032_RS01730	COG0438	transferase activity, transferring glycosyl groups
CS032_RS01730	COG1216	Glycosyl transferase, family 2
CS032_RS01760	COG1216	Glycosyl transferase, family 2
CS032_RS01760	COG0438	transferase activity, transferring glycosyl groups
CS032_RS01800	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CS032_RS01830	COG2165	general secretion pathway protein
CS032_RS01835	COG1459	type II secretion system
CS032_RS01840	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CS032_RS01860	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CS032_RS01870	COG3064	Membrane
CS032_RS01880	COG1620	l-lactate permease
CS032_RS01885	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CS032_RS01890	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CS032_RS01895	COG0247	lactate metabolic process
CS032_RS01900	COG0277	FAD linked oxidase domain protein
CS032_RS01905	COG0277	FAD linked oxidase domain protein
CS032_RS01910	COG2186	Transcriptional regulator
CS032_RS01915	COG0456	acetyltransferase
CS032_RS01925	COG0318	PFAM AMP-dependent synthetase and ligase
CS032_RS01935	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CS032_RS01940	COG0156	8-amino-7-oxononanoate synthase activity
CS032_RS01950	COG0795	lipopolysaccharide-transporting ATPase activity
CS032_RS01955	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CS032_RS01965	COG2244	polysaccharide biosynthetic process
CS032_RS01970	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CS032_RS01975	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CS032_RS01980	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CS032_RS01985	COG0306	phosphate transporter
CS032_RS01995	COG0754	glutathionylspermidine amidase activity
CS032_RS02000	COG0625	glutathione transferase activity
CS032_RS02005	COG0298	carbon dioxide binding
CS032_RS02015	COG1773	rubredoxin
CS032_RS02020	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CS032_RS02025	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CS032_RS02030	COG5557	Pfam Polysulphide reductase, NrfD
CS032_RS02035	COG0437	4 iron, 4 sulfur cluster binding
CS032_RS02040	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CS032_RS02060	COG0667	Aldo Keto reductase
CS032_RS02070	COG1028	Short-chain dehydrogenase reductase Sdr
CS032_RS02075	COG0848	biopolymer transport protein
CS032_RS02080	COG0811	peptide transport
CS032_RS02090	COG0626	cystathionine gamma-synthase activity
CS032_RS02095	COG0586	Pfam SNARE associated Golgi protein
CS032_RS02100	COG2207	Transcriptional regulator
CS032_RS02105	COG1979	alcohol dehydrogenase
CS032_RS02110	COG0656	L-ascorbic acid biosynthetic process
CS032_RS02120	COG4238	major outer membrane lipoprotein
CS032_RS02135	COG1032	radical SAM domain protein
CS032_RS02140	COG2132	Multicopper oxidase
CS032_RS02145	COG0204	Acyl-transferase
CS032_RS02150	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CS032_RS02155	COG4166	transmembrane transport
CS032_RS02160	COG2944	sequence-specific DNA binding
CS032_RS02180	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CS032_RS02185	COG3111	PFAM Bacterial OB fold (BOF) protein
CS032_RS02190	COG0745	RESPONSE REGULATOR receiver
CS032_RS02195	COG0642	Histidine kinase
CS032_RS02210	COG2249	NAD(P)H dehydrogenase (quinone) activity
CS032_RS02215	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CS032_RS02220	COG0187	DNA topoisomerase II activity
CS032_RS02230	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CS032_RS02235	COG3151	Protein conserved in bacteria
CS032_RS02240	COG0494	nUDIX hydrolase
CS032_RS02245	COG1538	Outer membrane efflux protein
CS032_RS02260	COG0754	glutathionylspermidine amidase activity
CS032_RS02265	COG3384	dioxygenase
CS032_RS02285	COG2960	long-chain fatty acid transporting porin activity
CS032_RS02290	COG3539	Fimbrial protein
CS032_RS02300	COG3121	Chaperone
CS032_RS02305	COG3539	Fimbrial protein
CS032_RS02320	COG2268	Band 7 protein
CS032_RS02345	COG3025	triphosphatase activity
CS032_RS02355	COG4991	sh3 domain protein
CS032_RS02370	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CS032_RS02380	COG0583	DNA-binding transcription factor activity
CS032_RS02390	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CS032_RS02395	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CS032_RS02400	COG0471	metal ion transport
CS032_RS02415	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CS032_RS02420	COG0358	DNA primase activity
CS032_RS02430	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CS032_RS02445	COG2375	cellular response to nickel ion
CS032_RS02450	COG1695	Transcriptional regulator
CS032_RS02455	COG0840	transmembrane signaling receptor activity
CS032_RS02470	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CS032_RS02480	COG1609	Transcriptional regulator
CS032_RS02485	COG3250	beta-galactosidase activity
CS032_RS02490	COG2731	YhcH YjgK YiaL family protein
CS032_RS02495	COG0531	amino acid
CS032_RS02505	COG3408	Glycogen debranching enzyme
CS032_RS02505	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
CS032_RS02510	COG1902	pentaerythritol trinitrate reductase activity
CS032_RS02510	COG0446	pyridine nucleotide-disulphide oxidoreductase
CS032_RS02515	COG5499	transcription regulator containing HTH domain
CS032_RS02520	COG4680	protein conserved in bacteria
CS032_RS02535	COG1451	nucleotide metabolic process
CS032_RS02540	COG2949	membrane
CS032_RS02545	COG0673	inositol 2-dehydrogenase activity
CS032_RS02550	COG0861	Integral membrane protein TerC family
CS032_RS02565	COG2721	sulfolactate sulfo-lyase activity
CS032_RS02575	COG2271	Major facilitator Superfamily
CS032_RS02580	COG2186	Transcriptional regulator
CS032_RS02585	COG0586	Pfam SNARE associated Golgi protein
CS032_RS02595	COG1422	Protein of unknown function (DUF1090)
CS032_RS02600	COG4575	ribosome binding
CS032_RS02605	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CS032_RS02615	COG2259	Doxx family
CS032_RS02620	COG0435	Glutathione S-transferase
CS032_RS02625	COG3152	Membrane
CS032_RS02630	COG3152	Membrane
CS032_RS02640	COG0583	DNA-binding transcription factor activity
CS032_RS02645	COG1741	Belongs to the pirin family
CS032_RS02660	COG0814	amino acid
CS032_RS02670	COG1760	l-serine dehydratase
CS032_RS02675	COG0251	oxidation-reduction process
CS032_RS02680	COG1882	Formate acetyltransferase
CS032_RS02685	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CS032_RS02695	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CS032_RS02705	COG0583	DNA-binding transcription factor activity
CS032_RS02730	COG1929	Belongs to the glycerate kinase type-1 family
CS032_RS02735	COG2084	Dehydrogenase
CS032_RS02745	COG2271	Major facilitator Superfamily
CS032_RS02750	COG2721	sulfolactate sulfo-lyase activity
CS032_RS02755	COG2002	toxin-antitoxin pair type II binding
CS032_RS02765	COG1349	DNA-binding transcription factor activity
CS032_RS02780	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CS032_RS02790	COG3716	PTS system mannose fructose sorbose family IID component
CS032_RS02795	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CS032_RS02800	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CS032_RS02805	COG2222	sugar isomerase
CS032_RS02815	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CS032_RS02820	COG3715	PTS system
CS032_RS02825	COG3716	PTS system mannose fructose sorbose family IID component
CS032_RS02830	COG0363	glucosamine-6-phosphate deaminase activity
CS032_RS02835	COG3539	Fimbrial protein
CS032_RS02840	COG3121	Chaperone
CS032_RS02845	COG3188	usher protein
CS032_RS02850	COG3539	Fimbrial protein
CS032_RS02855	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CS032_RS02860	COG3107	peptidoglycan biosynthetic process
CS032_RS02875	COG2823	Periplasmic or secreted lipoprotein
CS032_RS02880	COG0701	Predicted permease
CS032_RS02885	COG0702	epimerase
CS032_RS02890	COG0693	protein deglycase activity
CS032_RS02905	COG3153	acetyltransferase
CS032_RS02910	COG3154	lipid carrier protein
CS032_RS02915	COG0826	peptidase U32
CS032_RS02920	COG0826	peptidase U32
CS032_RS02925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CS032_RS02930	COG0814	amino acid
CS032_RS02935	COG0513	Belongs to the DEAD box helicase family
CS032_RS02975	COG0195	Participates in both transcription termination and antitermination
CS032_RS02995	COG2194	sulfuric ester hydrolase activity
CS032_RS03010	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CS032_RS03020	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CS032_RS03025	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CS032_RS03035	COG1534	Rna-binding protein
CS032_RS03040	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CS032_RS03045	COG2027	D-alanyl-D-alanine carboxypeptidase
CS032_RS03055	COG0697	spore germination
CS032_RS03070	COG0142	geranyltranstransferase activity
CS032_RS03075	COG3423	Transcriptional regulator
CS032_RS03085	COG5007	Belongs to the BolA IbaG family
CS032_RS03090	COG3113	response to antibiotic
CS032_RS03095	COG2854	intermembrane phospholipid transfer
CS032_RS03100	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CS032_RS03105	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CS032_RS03110	COG1127	ABC transporter
CS032_RS03115	COG0530	calcium, potassium:sodium antiporter activity
CS032_RS03120	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CS032_RS03120	COG0517	IMP dehydrogenase activity
CS032_RS03125	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CS032_RS03130	COG3117	lipopolysaccharide transmembrane transporter activity
CS032_RS03135	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CS032_RS03140	COG1137	ATPase activity
CS032_RS03145	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CS032_RS03150	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CS032_RS03165	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CS032_RS03170	COG0515	serine threonine protein kinase
CS032_RS03180	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CS032_RS03185	COG2198	Histidine kinase
CS032_RS03185	COG5002	protein histidine kinase activity
CS032_RS03185	COG0784	Response regulator, receiver
CS032_RS03190	COG1242	4 iron, 4 sulfur cluster binding
CS032_RS03205	COG0070	glutamate synthase
CS032_RS03205	COG0067	glutamate synthase
CS032_RS03205	COG0069	glutamate synthase activity
CS032_RS03210	COG0493	'glutamate synthase
CS032_RS03225	COG4804	nuclease activity
CS032_RS03230	COG2731	YhcH YjgK YiaL family protein
CS032_RS03265	COG3069	C4-dicarboxylate transmembrane transporter activity
CS032_RS03270	COG2969	positive regulation of protein catabolic process
CS032_RS03275	COG0625	glutathione transferase activity
CS032_RS03295	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CS032_RS03300	COG3105	Protein conserved in bacteria
CS032_RS03305	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CS032_RS03310	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CS032_RS03330	COG2732	(Barnase) inhibitor
CS032_RS03350	COG0583	DNA-binding transcription factor activity
CS032_RS03355	COG0312	modulator of DNA gyrase
CS032_RS03360	COG3164	Protein of unknown function
CS032_RS03365	COG1530	ribonuclease E activity
CS032_RS03370	COG0424	maF-like protein
CS032_RS03375	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CS032_RS03380	COG1792	Involved in formation and maintenance of cell shape
CS032_RS03385	COG1077	Cell shape determining protein MreB Mrl
CS032_RS03400	COG2200	EAL domain
CS032_RS03400	COG2199	diguanylate cyclase activity
CS032_RS03405	COG0604	alcohol dehydrogenase
CS032_RS03415	COG0511	ligase activity, forming carbon-carbon bonds
CS032_RS03420	COG0439	Biotin carboxylase
CS032_RS03425	COG3924	membrane
CS032_RS03430	COG4145	pantothenate transmembrane transporter activity
CS032_RS03440	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CS032_RS03450	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CS032_RS03460	COG1309	transcriptional regulator
CS032_RS03470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CS032_RS03475	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CS032_RS03490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS032_RS03495	COG4597	amino acid ABC transporter
CS032_RS03500	COG0765	amino acid transport
CS032_RS03505	COG1126	abc transporter atp-binding protein
CS032_RS03545	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CS032_RS03565	COG0551	DNA topoisomerase type I activity
CS032_RS03575	COG0758	DNA mediated transformation
CS032_RS03595	COG0569	domain protein
CS032_RS03610	COG0789	Transcriptional regulator
CS032_RS03650	COG0201	protein transport
CS032_RS03740	COG0089	rRNA binding
CS032_RS03770	COG3409	Peptidoglycan-binding domain 1 protein
CS032_RS03770	COG3267	Type II secretory pathway component ExeA
CS032_RS03775	COG3031	protein transport across the cell outer membrane
CS032_RS03780	COG1450	Type ii and iii secretion system protein
CS032_RS03785	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CS032_RS03790	COG1459	type II secretion system
CS032_RS03795	COG2165	general secretion pathway protein
CS032_RS03800	COG2165	general secretion pathway protein
CS032_RS03805	COG2165	general secretion pathway protein
CS032_RS03810	COG4795	General secretion pathway protein
CS032_RS03815	COG3156	type II secretion system protein K
CS032_RS03820	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CS032_RS03825	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CS032_RS03830	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CS032_RS03835	COG2193	ferroxidase activity
CS032_RS03840	COG2906	2 iron, 2 sulfur cluster binding
CS032_RS03845	COG3979	chitinase
CS032_RS03890	COG2964	Protein conserved in bacteria
CS032_RS03895	COG0545	Peptidyl-prolyl cis-trans isomerase
CS032_RS03905	COG1047	Peptidyl-prolyl cis-trans
CS032_RS03910	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CS032_RS03930	COG0488	(ABC) transporter
CS032_RS03935	COG0429	hydrolase of the alpha beta-hydrolase fold
CS032_RS03945	COG3954	Phosphoribulokinase
CS032_RS03950	COG1765	OsmC-like protein
CS032_RS03960	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CS032_RS03965	COG1289	transmembrane transporter activity
CS032_RS03970	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CS032_RS03975	COG0512	Glutamine amidotransferase of anthranilate synthase
CS032_RS03980	COG2184	nucleotidyltransferase activity
CS032_RS03990	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CS032_RS04000	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CS032_RS04005	COG2146	nitrite reductase [NAD(P)H] activity
CS032_RS04010	COG2116	formate transmembrane transporter activity
CS032_RS04025	COG0531	amino acid
CS032_RS04030	COG2222	sugar isomerase
CS032_RS04040	COG1082	Xylose isomerase domain protein TIM barrel
CS032_RS04045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CS032_RS04050	COG2188	Transcriptional regulator
CS032_RS04055	COG0626	cystathionine gamma-synthase activity
CS032_RS04070	COG1735	metal-dependent hydrolase with the TIM-barrel fold
CS032_RS04080	COG3457	Alanine racemase
CS032_RS04090	COG2188	Transcriptional regulator
CS032_RS04100	COG0180	Tryptophanyl-tRNA synthetase
CS032_RS04105	COG0546	phosphoglycolate phosphatase activity
CS032_RS04110	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CS032_RS04115	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CS032_RS04120	COG3266	domain, Protein
CS032_RS04135	COG4796	Type ii and iii secretion system protein
CS032_RS04155	COG4972	Pilus assembly protein
CS032_RS04160	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CS032_RS04165	COG0494	nUDIX hydrolase
CS032_RS04175	COG1011	Hydrolase
CS032_RS04180	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CS032_RS04190	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CS032_RS04220	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CS032_RS04225	COG2183	response to ionizing radiation
CS032_RS04235	COG1918	ferrous iron import across plasma membrane
CS032_RS04240	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CS032_RS04255	COG5464	transposase or invertase
CS032_RS04265	COG1040	competence protein
CS032_RS04275	COG2610	gluconate transmembrane transporter activity
CS032_RS04285	COG0058	SHG alpha-glucan phosphorylase activity
CS032_RS04300	COG1690	Belongs to the RtcB family
CS032_RS04305	COG4650	regulator
CS032_RS04310	COG1349	DNA-binding transcription factor activity
CS032_RS04325	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CS032_RS04330	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CS032_RS04335	COG0058	SHG alpha-glucan phosphorylase activity
CS032_RS04360	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CS032_RS04365	COG2095	MarC family integral membrane protein
CS032_RS04370	COG2610	gluconate transmembrane transporter activity
CS032_RS04375	COG3265	gluconokinase activity
CS032_RS04380	COG1609	Transcriptional regulator
CS032_RS04385	COG1741	Belongs to the pirin family
CS032_RS04390	COG0673	inositol 2-dehydrogenase activity
CS032_RS04400	COG1247	-acetyltransferase
CS032_RS04405	COG3157	Type VI secretion system effector, Hcp
CS032_RS04425	COG0405	Gamma-glutamyltransferase
CS032_RS04435	COG0584	glycerophosphoryl diester phosphodiesterase
CS032_RS04440	COG3842	ATPase activity
CS032_RS04445	COG0395	ABC-type sugar transport system, permease component
CS032_RS04450	COG1175	transmembrane transport
CS032_RS04455	COG1653	transport
CS032_RS04460	COG0410	ABC transporter
CS032_RS04465	COG0411	ABC transporter
CS032_RS04470	COG4177	L-phenylalanine transmembrane transporter activity
CS032_RS04475	COG0559	Belongs to the binding-protein-dependent transport system permease family
CS032_RS04480	COG0683	leucine binding
CS032_RS04490	COG0456	acetyltransferase
CS032_RS04495	COG0683	leucine binding
CS032_RS04500	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CS032_RS04505	COG2177	Part of the ABC transporter FtsEX involved in
CS032_RS04510	COG2884	Cell division ATP-binding protein ftsE
CS032_RS04515	COG0552	protein localization to endoplasmic reticulum
CS032_RS04520	COG0742	ribosomal rna small subunit methyltransferase
CS032_RS04525	COG3776	membrane
CS032_RS04535	COG3714	YhhN family
CS032_RS04540	COG2217	Heavy metal translocating P-type atpase
CS032_RS04550	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CS032_RS04560	COG0477	Major facilitator Superfamily
CS032_RS04565	COG0628	permease
CS032_RS04570	COG2091	lysine biosynthetic process via aminoadipic acid
CS032_RS04575	COG0747	negative chemotaxis
CS032_RS04580	COG0601	transmembrane transport
CS032_RS04585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS032_RS04590	COG0444	Belongs to the ABC transporter superfamily
CS032_RS04595	COG1124	(ABC) transporter
CS032_RS04615	COG1413	lyase activity
CS032_RS04620	COG5433	transposase activity
CS032_RS04625	COG0842	Transport permease protein
CS032_RS04630	COG1129	ABC transporter
CS032_RS04630	COG0842	Transport permease protein
CS032_RS04635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CS032_RS04675	COG4372	Transposase
CS032_RS04680	COG3436	PFAM IS66 Orf2 family protein
CS032_RS04725	COG2081	HI0933 family
CS032_RS04730	COG0306	phosphate transporter
CS032_RS04740	COG0589	response to stress
CS032_RS04750	COG3104	oligopeptide transport
CS032_RS04760	COG0339	signal peptide processing
CS032_RS04765	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CS032_RS04770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CS032_RS04785	COG0640	Transcriptional regulator
CS032_RS04790	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CS032_RS04795	COG1393	Belongs to the ArsC family
CS032_RS04815	COG3065	identical protein binding
CS032_RS04825	COG2197	response regulator
CS032_RS04830	COG1285	pathogenesis
CS032_RS04845	COG3247	response to pH
CS032_RS04850	COG2771	luxR family
CS032_RS04860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CS032_RS04865	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CS032_RS04875	COG2207	Transcriptional regulator
CS032_RS04880	COG2207	Transcriptional regulator
CS032_RS04885	COG0076	glutamate decarboxylase activity
CS032_RS04890	COG1858	cytochrome C peroxidase
CS032_RS04900	COG2197	response regulator
CS032_RS04905	COG0583	DNA-binding transcription factor activity
CS032_RS04910	COG1295	ribonuclease BN
CS032_RS04915	COG0477	Major facilitator Superfamily
CS032_RS04920	COG2982	Protein involved in outer membrane biogenesis
CS032_RS04925	COG2200	EAL domain
CS032_RS04935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CS032_RS04940	COG0612	Peptidase, M16
CS032_RS04955	COG2200	EAL domain
CS032_RS04955	COG2199	diguanylate cyclase activity
CS032_RS04960	COG0457	Tetratricopeptide repeat
CS032_RS04960	COG3118	belongs to the thioredoxin family
CS032_RS04965	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CS032_RS04970	COG1215	transferase activity, transferring glycosyl groups
CS032_RS04975	COG1215	transferase activity, transferring glycosyl groups
CS032_RS05000	COG2194	sulfuric ester hydrolase activity
CS032_RS05020	COG0814	amino acid
CS032_RS05025	COG4608	Belongs to the ABC transporter superfamily
CS032_RS05030	COG0444	Belongs to the ABC transporter superfamily
CS032_RS05035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS032_RS05040	COG0601	transmembrane transport
CS032_RS05045	COG0747	negative chemotaxis
CS032_RS05060	COG2194	sulfuric ester hydrolase activity
CS032_RS05065	COG2223	nitrite transmembrane transporter activity
CS032_RS05075	COG5571	outer membrane autotransporter
CS032_RS05080	COG2818	Glycosylase
CS032_RS05085	COG0456	acetyltransferase
CS032_RS05090	COG0243	molybdopterin cofactor binding
CS032_RS05095	COG2885	chlorophyll binding
CS032_RS05110	COG2944	sequence-specific DNA binding
CS032_RS05115	COG1278	Cold shock
CS032_RS05145	COG3274	enterobacterial common antigen metabolic process
CS032_RS05150	COG4682	membrane
CS032_RS05155	COG4682	membrane
CS032_RS05160	COG1070	Carbohydrate kinase
CS032_RS05170	COG4213	ABC transporter substrate-binding protein
CS032_RS05175	COG1129	ABC transporter
CS032_RS05180	COG4214	carbohydrate transport
CS032_RS05185	COG2207	Transcriptional regulator
CS032_RS05185	COG1609	Transcriptional regulator
CS032_RS05190	COG2992	FlgJ-related protein
CS032_RS05195	COG0366	Alpha amylase catalytic
CS032_RS05200	COG3977	Valine--pyruvate aminotransferase
CS032_RS05205	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CS032_RS05210	COG1414	Transcriptional regulator
CS032_RS05220	COG2731	YhcH YjgK YiaL family protein
CS032_RS05225	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CS032_RS05230	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CS032_RS05235	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CS032_RS05240	COG1070	Carbohydrate kinase
CS032_RS05245	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CS032_RS05250	COG3623	hexulose-6-phosphate isomerase
CS032_RS05255	COG0235	Class ii aldolase
CS032_RS05265	COG3713	MltA-interacting MipA family protein
CS032_RS05270	COG0583	DNA-binding transcription factor activity
CS032_RS05275	COG1566	PFAM secretion protein HlyD family protein
CS032_RS05295	COG1012	belongs to the aldehyde dehydrogenase family
CS032_RS05300	COG1454	alcohol dehydrogenase
CS032_RS05305	COG3276	selenocysteine insertion sequence binding
CS032_RS05315	COG0625	glutathione transferase activity
CS032_RS05320	COG3209	COG3209 Rhs family protein
CS032_RS05325	COG1413	lyase activity
CS032_RS05330	COG3209	COG3209 Rhs family protein
CS032_RS05335	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CS032_RS05355	COG1566	PFAM secretion protein HlyD family protein
CS032_RS05365	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CS032_RS05365	COG2213	PTS system mannitol-specific
CS032_RS05375	COG3722	fumarate hydratase activity
CS032_RS05395	COG1620	l-lactate permease
CS032_RS05400	COG2186	Transcriptional regulator
CS032_RS05410	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CS032_RS05415	COG1045	serine acetyltransferase
CS032_RS05430	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CS032_RS05435	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CS032_RS05445	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CS032_RS05450	COG4942	peptidase
CS032_RS05455	COG2861	carbohydrate metabolic process
CS032_RS05460	COG1216	Glycosyl transferase, family 2
CS032_RS05470	COG0156	8-amino-7-oxononanoate synthase activity
CS032_RS05485	COG0859	PFAM glycosyl transferase family 9
CS032_RS05490	COG0859	PFAM glycosyl transferase family 9
CS032_RS05495	COG3307	-O-antigen
CS032_RS05500	COG1216	Glycosyl transferase, family 2
CS032_RS05505	COG1442	glycosyl transferase family 8
CS032_RS05510	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CS032_RS05525	COG0515	serine threonine protein kinase
CS032_RS05530	COG0438	transferase activity, transferring glycosyl groups
CS032_RS05535	COG0859	PFAM glycosyl transferase family 9
CS032_RS05540	COG1519	Transferase
CS032_RS05570	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CS032_RS05600	COG1561	YicC-like family, N-terminal region
CS032_RS05605	COG3645	SOS response
CS032_RS05610	COG2860	membrane
CS032_RS05620	COG0194	GDP metabolic process
CS032_RS05630	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CS032_RS05635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CS032_RS05640	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CS032_RS05645	COG0786	glutamate:sodium symporter activity
CS032_RS05650	COG2233	PERMEase
CS032_RS05655	COG2982	Protein involved in outer membrane biogenesis
CS032_RS05660	COG1501	Belongs to the glycosyl hydrolase 31 family
CS032_RS05665	COG2211	Major facilitator Superfamily
CS032_RS05685	COG0697	spore germination
CS032_RS05690	COG1464	Belongs to the NlpA lipoprotein family
CS032_RS05720	COG2252	PERMEase
CS032_RS05730	COG2271	Major facilitator Superfamily
CS032_RS05735	COG2271	Major facilitator Superfamily
CS032_RS05745	COG2197	response regulator
CS032_RS05750	COG0440	acetolactate synthase activity
CS032_RS05755	COG0028	Belongs to the TPP enzyme family
CS032_RS05790	COG2814	Major facilitator Superfamily
CS032_RS05795	COG0641	radical SAM
CS032_RS05805	COG2149	membrane
CS032_RS05810	COG0675	Transposase, IS605 OrfB family
CS032_RS05835	COG2188	Transcriptional regulator
CS032_RS05855	COG5645	(Lipo)protein
CS032_RS05860	COG0823	Involved in the tonB-independent uptake of proteins
CS032_RS05865	COG0644	oxidoreductase
CS032_RS05870	COG2271	Major facilitator Superfamily
CS032_RS05880	COG0800	Aldolase
CS032_RS05885	COG3734	2-keto-3-deoxy-galactonokinase
CS032_RS05890	COG2186	Transcriptional regulator
CS032_RS05900	COG0561	phosphatase activity
CS032_RS05905	COG3753	Protein conserved in bacteria
CS032_RS05910	COG0187	DNA topoisomerase II activity
CS032_RS05920	COG0592	DNA-directed DNA polymerase activity
CS032_RS05970	COG0814	amino acid
CS032_RS05985	COG2091	lysine biosynthetic process via aminoadipic acid
CS032_RS05990	COG0431	NADPH-dependent FMN reductase
CS032_RS05995	COG2252	PERMEase
CS032_RS06000	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CS032_RS06010	COG3196	Protein conserved in bacteria
CS032_RS06015	COG0363	glucosamine-6-phosphate deaminase activity
CS032_RS06020	COG2382	esterase
CS032_RS06030	COG2723	6-phospho-beta-galactosidase activity
CS032_RS06035	COG1263	PTS System
CS032_RS06035	COG2190	(PTS) system
CS032_RS06035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CS032_RS06040	COG3711	transcriptional antiterminator
CS032_RS06045	COG0704	Plays a role in the regulation of phosphate uptake
CS032_RS06050	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CS032_RS06055	COG0581	inorganic phosphate transmembrane transporter activity
CS032_RS06060	COG0573	inorganic phosphate transmembrane transporter activity
CS032_RS06065	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CS032_RS06070	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CS032_RS06120	COG3312	ion transport
CS032_RS06135	COG0716	FMN binding
CS032_RS06140	COG1522	sequence-specific DNA binding
CS032_RS06170	COG1129	ABC transporter
CS032_RS06175	COG1172	Belongs to the binding-protein-dependent transport system permease family
CS032_RS06180	COG1879	ABC-type sugar transport system periplasmic component
CS032_RS06185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CS032_RS06190	COG1609	Transcriptional regulator
CS032_RS06195	COG0477	Major facilitator Superfamily
CS032_RS06200	COG2186	Transcriptional regulator
CS032_RS06240	COG3085	chromosome segregation
CS032_RS06245	COG0606	chelatase, subunit chli
CS032_RS06265	COG3978	acetolactate synthase activity
CS032_RS06270	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CS032_RS06280	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CS032_RS06285	COG0583	DNA-binding transcription factor activity
CS032_RS06295	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CS032_RS06300	COG3692	DNA binding
CS032_RS06305	COG0210	DNA helicase
CS032_RS06325	COG3118	belongs to the thioredoxin family
CS032_RS06335	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CS032_RS06345	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CS032_RS06355	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CS032_RS06360	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CS032_RS06365	COG1088	dTDP-glucose 4,6-dehydratase activity
CS032_RS06370	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CS032_RS06375	COG0456	acetyltransferase
CS032_RS06380	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CS032_RS06385	COG2244	polysaccharide biosynthetic process
CS032_RS06405	COG1113	amino acid transport
CS032_RS06430	COG0641	radical SAM
CS032_RS06435	COG3119	arylsulfatase activity
CS032_RS06440	COG3071	HemY protein
CS032_RS06445	COG2959	enzyme of heme biosynthesis
CS032_RS06450	COG1587	Uroporphyrinogen-III synthase
CS032_RS06465	COG3072	Adenylate cyclase
CS032_RS06475	COG5567	small periplasmic lipoprotein
CS032_RS06485	COG3159	Protein conserved in bacteria
CS032_RS06495	COG1011	Hydrolase
CS032_RS06500	COG0210	DNA helicase
CS032_RS06505	COG3698	Phosphodiester glycosidase
CS032_RS06510	COG0598	Magnesium transport protein CorA
CS032_RS06525	COG2962	Rard protein
CS032_RS06530	COG2050	protein possibly involved in aromatic compounds catabolism
CS032_RS06535	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
CS032_RS06540	COG0514	ATP-dependent DNA helicase (RecQ)
CS032_RS06545	COG1280	lysine exporter protein (LysE YggA)
CS032_RS06550	COG1280	lysine exporter protein (LysE YggA)
CS032_RS06555	COG2267	carboxylic ester hydrolase activity
CS032_RS06560	COG0561	phosphatase activity
CS032_RS06565	COG0697	spore germination
CS032_RS06570	COG0583	DNA-binding transcription factor activity
CS032_RS06580	COG0412	Dienelactone hydrolase
CS032_RS06585	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CS032_RS06595	COG1322	Protein conserved in bacteria
CS032_RS06605	COG3165	ubiquinone biosynthetic process from chorismate
CS032_RS06615	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CS032_RS06620	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CS032_RS06625	COG0805	protein transport
CS032_RS06630	COG0084	hydrolase, TatD family'
CS032_RS06635	COG0250	Participates in transcription elongation, termination and antitermination
CS032_RS06640	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CS032_RS06645	COG0543	2 iron, 2 sulfur cluster binding
CS032_RS06650	COG0183	Belongs to the thiolase family
CS032_RS06665	COG1739	Uncharacterized protein family UPF0029
CS032_RS06670	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CS032_RS06675	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CS032_RS06705	COG1763	Mo-molybdopterin cofactor biosynthetic process
CS032_RS06710	COG0746	molybdenum cofactor guanylyltransferase activity
CS032_RS06715	COG3084	Protein conserved in bacteria
CS032_RS06720	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CS032_RS06725	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CS032_RS06730	COG5339	Protein conserved in bacteria
CS032_RS06750	COG0204	Acyl-transferase
CS032_RS06760	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CS032_RS06760	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CS032_RS06775	COG3078	GTPase activator activity
CS032_RS06780	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CS032_RS06790	COG2204	response regulator
CS032_RS06795	COG3852	Histidine kinase
CS032_RS06800	COG0174	glutamine synthetase
CS032_RS06810	COG1217	gtp-binding protein TYPA
CS032_RS06815	COG2188	Transcriptional regulator
CS032_RS06820	COG1082	Xylose isomerase domain protein TIM barrel
CS032_RS06825	COG2271	Major facilitator Superfamily
CS032_RS06830	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CS032_RS06835	COG2211	Major facilitator Superfamily
CS032_RS06840	COG2211	Major facilitator Superfamily
CS032_RS06845	COG1501	Belongs to the glycosyl hydrolase 31 family
CS032_RS06855	COG2017	converts alpha-aldose to the beta-anomer
CS032_RS06860	COG2942	2-epimerase
CS032_RS06865	COG3684	Belongs to the aldolase LacD family
CS032_RS06870	COG2084	Dehydrogenase
CS032_RS06875	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CS032_RS06880	COG1349	DNA-binding transcription factor activity
CS032_RS06885	COG1011	Hydrolase
CS032_RS06900	COG0456	acetyltransferase
CS032_RS06905	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CS032_RS06910	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CS032_RS06920	COG2864	formate dehydrogenase
CS032_RS06925	COG0437	4 iron, 4 sulfur cluster binding
CS032_RS06950	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CS032_RS06950	COG3711	transcriptional antiterminator
CS032_RS06955	COG1363	Peptidase, m42
CS032_RS06960	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CS032_RS06960	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CS032_RS06965	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CS032_RS07005	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CS032_RS07020	COG2258	MOSC domain
CS032_RS07025	COG2205	protein histidine kinase activity
CS032_RS07030	COG0745	RESPONSE REGULATOR receiver
CS032_RS07035	COG3678	ATP-independent chaperone mediated protein folding
CS032_RS07050	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CS032_RS07070	COG3152	Membrane
CS032_RS07075	COG3691	Protein conserved in bacteria
CS032_RS07080	COG0589	response to stress
CS032_RS07085	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CS032_RS07090	COG1494	fructose-1,6-bisphosphatase
CS032_RS07100	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CS032_RS07115	COG1575	Belongs to the MenA family. Type 1 subfamily
CS032_RS07130	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CS032_RS07135	COG1609	Transcriptional regulator
CS032_RS07150	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
CS032_RS07160	COG0626	cystathionine gamma-synthase activity
CS032_RS07165	COG0460	homoserine dehydrogenase
CS032_RS07165	COG0527	aspartate kinase activity
CS032_RS07170	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CS032_RS07180	COG0697	spore germination
CS032_RS07185	COG3738	Protein conserved in bacteria
CS032_RS07190	COG0371	Dehydrogenase
CS032_RS07195	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CS032_RS07200	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CS032_RS07200	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CS032_RS07200	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CS032_RS07205	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CS032_RS07210	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CS032_RS07215	COG1882	Formate acetyltransferase
CS032_RS07220	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CS032_RS07225	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CS032_RS07230	COG2207	Transcriptional regulator
CS032_RS07235	COG2194	sulfuric ester hydrolase activity
CS032_RS07255	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CS032_RS07270	COG0583	DNA-binding transcription factor activity
CS032_RS07300	COG4206	TonB-dependent receptor
CS032_RS07330	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CS032_RS07335	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CS032_RS07335	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CS032_RS07380	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CS032_RS07385	COG0250	Participates in transcription elongation, termination and antitermination
CS032_RS07430	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CS032_RS07440	COG2104	thiamine diphosphate biosynthetic process
CS032_RS07445	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CS032_RS07480	COG3068	Protein conserved in bacteria
CS032_RS07495	COG3678	ATP-independent chaperone mediated protein folding
CS032_RS07510	COG2204	response regulator
CS032_RS07515	COG0151	Belongs to the GarS family
CS032_RS07555	COG0456	acetyltransferase
CS032_RS07565	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CS032_RS07570	COG2224	Isocitrate lyase
CS032_RS07585	COG1414	Transcriptional regulator
CS032_RS07590	COG1410	methionine synthase
CS032_RS07590	COG0646	methionine synthase
CS032_RS07595	COG1283	sodium-dependent phosphate transmembrane transporter activity
CS032_RS07605	COG1187	pseudouridine synthase activity
CS032_RS07615	COG0527	aspartate kinase activity
CS032_RS07650	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CS032_RS07665	COG2814	Major facilitator Superfamily
CS032_RS07665	COG0477	Major facilitator Superfamily
CS032_RS07670	COG3833	ABC-type maltose transport systems, permease component
CS032_RS07675	COG1175	transmembrane transport
CS032_RS07680	COG2182	Extracellular solute-binding protein
CS032_RS07690	COG3842	ATPase activity
CS032_RS07710	COG1357	PFAM Pentapeptide repeats (8 copies)
CS032_RS07735	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CS032_RS07745	COG0534	Mate efflux family protein
CS032_RS07750	COG3237	CsbD-like
CS032_RS07755	COG0735	belongs to the Fur family
CS032_RS07765	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CS032_RS07775	COG0604	alcohol dehydrogenase
CS032_RS07780	COG0305	Participates in initiation and elongation during chromosome replication
CS032_RS07785	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CS032_RS07790	COG1448	Aminotransferase
CS032_RS07800	COG3700	Belongs to the class B bacterial acid phosphatase family
CS032_RS07805	COG0432	Pfam Uncharacterised protein family UPF0047
CS032_RS07810	COG2315	Protein conserved in bacteria
CS032_RS07815	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CS032_RS07825	COG0629	single-stranded DNA binding
CS032_RS07845	COG2207	Transcriptional regulator
CS032_RS07850	COG0789	Transcriptional regulator
CS032_RS07870	COG2252	PERMEase
CS032_RS07875	COG0025	NhaP-type Na H and K H
CS032_RS07880	COG1357	PFAM Pentapeptide repeats (8 copies)
CS032_RS07890	COG3162	membrane
CS032_RS07895	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CS032_RS07910	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CS032_RS07915	COG0437	4 iron, 4 sulfur cluster binding
CS032_RS07920	COG3301	Polysulphide reductase, NrfD
CS032_RS07930	COG3088	subunit of a heme lyase
CS032_RS07935	COG4235	cytochrome complex assembly
CS032_RS07945	COG1301	dicarboxylic acid transport
CS032_RS07950	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CS032_RS07960	COG1538	Outer membrane efflux protein
CS032_RS07965	COG1289	transmembrane transporter activity
CS032_RS07970	COG1566	PFAM secretion protein HlyD family protein
CS032_RS07980	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CS032_RS07985	COG1940	carbohydrate kinase activity
CS032_RS07990	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CS032_RS07995	COG1172	Belongs to the binding-protein-dependent transport system permease family
CS032_RS08005	COG1879	ABC-type sugar transport system periplasmic component
CS032_RS08010	COG1737	Transcriptional regulator
CS032_RS08020	COG0698	ribose 5-phosphate isomerase
CS032_RS08030	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CS032_RS08035	COG0456	acetyltransferase
CS032_RS08040	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CS032_RS08045	COG3454	Phosphonate metabolism
CS032_RS08050	COG4778	phosphonate C-P lyase system protein PhnL
CS032_RS08055	COG4107	phosphonate C-P lyase system protein PhnK
CS032_RS08060	COG3627	carbon phosphorus lyase activity
CS032_RS08065	COG3626	phosphonate metabolism
CS032_RS08070	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CS032_RS08075	COG3624	Phosphonate C-P lyase system protein PhnG
CS032_RS08080	COG2188	Transcriptional regulator
CS032_RS08085	COG3639	organic phosphonate transmembrane transporter activity
CS032_RS08090	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CS032_RS08100	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CS032_RS08105	COG2824	Alkylphosphonate utilization operon protein PhnA
CS032_RS08125	COG0477	Major facilitator Superfamily
CS032_RS08135	COG0642	Histidine kinase
CS032_RS08140	COG0745	RESPONSE REGULATOR receiver
CS032_RS08145	COG2194	sulfuric ester hydrolase activity
CS032_RS08150	COG0531	amino acid
CS032_RS08155	COG2207	Transcriptional regulator
CS032_RS08160	COG1982	Orn Lys Arg decarboxylase major
CS032_RS08165	COG2169	Transcriptional regulator
CS032_RS08170	COG1486	melibiose metabolic process
CS032_RS08175	COG2211	Major facilitator Superfamily
CS032_RS08180	COG3647	Membrane
CS032_RS08185	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CS032_RS08185	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CS032_RS08190	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CS032_RS08200	COG4565	transcriptional regulatory protein
CS032_RS08205	COG3290	protein histidine kinase activity
CS032_RS08210	COG3592	Divergent 4Fe-4S mono-cluster
CS032_RS08215	COG2388	GCN5-related N-acetyl-transferase
CS032_RS08250	COG1309	transcriptional regulator
CS032_RS08265	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CS032_RS08270	COG1027	Aspartate ammonia-lyase
CS032_RS08275	COG3030	protein affecting phage T7 exclusion by the F plasmid
CS032_RS08280	COG0531	amino acid
CS032_RS08305	COG1509	lysine 2,3-aminomutase activity
CS032_RS08315	COG5510	response to toxic substance
CS032_RS08320	COG5510	response to toxic substance
CS032_RS08325	COG2076	Multidrug Resistance protein
CS032_RS08330	COG3040	lipid binding
CS032_RS08335	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CS032_RS08350	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CS032_RS08355	COG1053	succinate dehydrogenase
CS032_RS08365	COG0531	amino acid
CS032_RS08380	COG3264	Mechanosensitive ion channel
CS032_RS08380	COG1511	domain protein
CS032_RS08420	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CS032_RS08425	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CS032_RS08425	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CS032_RS08430	COG0802	atpase or kinase
CS032_RS08435	COG0860	N-Acetylmuramoyl-L-alanine amidase
CS032_RS08455	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CS032_RS08460	COG0330	HflC and HflK could
CS032_RS08465	COG0330	HflC and HflK could
CS032_RS08470	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CS032_RS08485	COG0557	exoribonuclease II activity
CS032_RS08490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CS032_RS08500	COG3789	protein conserved in bacteria
CS032_RS08505	COG1842	Phage shock protein A
CS032_RS08515	COG3766	membrane
CS032_RS08520	COG5463	Belongs to the UPF0441 family
CS032_RS08525	COG0754	glutathionylspermidine amidase activity
CS032_RS08530	COG1960	acyl-CoA dehydrogenase activity
CS032_RS08545	COG3650	response to hydrogen peroxide
CS032_RS08550	COG1073	alpha beta
CS032_RS08565	COG3037	sugar-specific permease SgaT UlaA
CS032_RS08570	COG3414	Phosphotransferase system galactitol-specific IIB component
CS032_RS08610	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CS032_RS08620	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CS032_RS08630	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CS032_RS08635	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CS032_RS08640	COG4670	ketone body catabolic process
CS032_RS08645	COG1024	Enoyl-CoA hydratase
CS032_RS08660	COG1309	transcriptional regulator
CS032_RS08665	COG3061	Opacity-associated protein A
CS032_RS08675	COG0545	Peptidyl-prolyl cis-trans isomerase
CS032_RS08680	COG1113	amino acid transport
CS032_RS08690	COG0697	spore germination
CS032_RS08695	COG0702	epimerase
CS032_RS08700	COG1733	regulation of RNA biosynthetic process
CS032_RS08705	COG0737	Belongs to the 5'-nucleotidase family
CS032_RS08710	COG1218	3'(2'),5'-bisphosphate nucleotidase
CS032_RS08715	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CS032_RS08725	COG1253	flavin adenine dinucleotide binding
CS032_RS08740	COG0729	surface antigen
CS032_RS08745	COG2911	Protein conserved in bacteria
CS032_RS08750	COG2105	PFAM AIG2 family protein
CS032_RS08755	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CS032_RS08760	COG1879	ABC-type sugar transport system periplasmic component
CS032_RS08765	COG1129	ABC transporter
CS032_RS08770	COG1172	Belongs to the binding-protein-dependent transport system permease family
CS032_RS08775	COG1172	Belongs to the binding-protein-dependent transport system permease family
CS032_RS08785	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CS032_RS08795	COG0312	modulator of DNA gyrase
CS032_RS08800	COG3783	Cytochrome b(562)
CS032_RS08805	COG0602	queuosine metabolic process
CS032_RS08810	COG1328	CTP reductase activity
CS032_RS08815	COG0366	Alpha amylase catalytic
CS032_RS08820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CS032_RS08820	COG1263	PTS System
CS032_RS08825	COG1609	Transcriptional regulator
CS032_RS08835	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CS032_RS08840	COG0251	oxidation-reduction process
CS032_RS08865	COG0251	oxidation-reduction process
CS032_RS08870	COG1028	Short-chain dehydrogenase reductase Sdr
CS032_RS08875	COG1309	transcriptional regulator
CS032_RS08880	COG2731	YhcH YjgK YiaL family protein
CS032_RS08890	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CS032_RS08895	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
CS032_RS08900	COG0456	acetyltransferase
CS032_RS08905	COG4269	membrane
CS032_RS08915	COG2927	DNA polymerase III (CHI subunit)
CS032_RS08925	COG0795	lipopolysaccharide-transporting ATPase activity
CS032_RS08930	COG0795	lipopolysaccharide-transporting ATPase activity
CS032_RS08940	COG1064	alcohol dehydrogenase
CS032_RS08950	COG0582	viral genome integration into host DNA
CS032_RS08960	COG1204	response to ionizing radiation
CS032_RS08990	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CS032_RS09015	COG0604	alcohol dehydrogenase
CS032_RS09050	COG0440	acetolactate synthase activity
CS032_RS09055	COG1349	DNA-binding transcription factor activity
CS032_RS09065	COG0738	Major facilitator superfamily
CS032_RS09095	COG3436	PFAM IS66 Orf2 family protein
CS032_RS09100	COG4372	Transposase
CS032_RS09140	COG2826	transposase and inactivated derivatives, IS30 family
CS032_RS09145	COG2963	transposase activity
CS032_RS09155	COG2085	NADP oxidoreductase coenzyme F420-dependent
CS032_RS09160	COG1120	ATPase activity
CS032_RS09165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CS032_RS09170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CS032_RS09175	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CS032_RS09180	COG4772	TonB-dependent receptor
CS032_RS09185	COG3712	iron ion homeostasis
CS032_RS09190	COG1595	DNA-templated transcription, initiation
CS032_RS09255	COG1401	restriction endodeoxyribonuclease activity
CS032_RS09280	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
CS032_RS09285	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CS032_RS09300	COG0582	viral genome integration into host DNA
CS032_RS09305	COG4974	Belongs to the 'phage' integrase family
CS032_RS09320	COG3539	Fimbrial protein
CS032_RS09325	COG3121	Chaperone
CS032_RS09330	COG3188	usher protein
CS032_RS09335	COG3539	Fimbrial protein
CS032_RS09340	COG3539	Fimbrial protein
CS032_RS09345	COG3539	Fimbrial protein
CS032_RS09350	COG2610	gluconate transmembrane transporter activity
CS032_RS09365	COG0246	Mannitol dehydrogenase
CS032_RS09375	COG2186	Transcriptional regulator
CS032_RS09395	COG0583	DNA-binding transcription factor activity
CS032_RS09400	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CS032_RS09405	COG0700	Nucleoside recognition
CS032_RS09410	COG3366	ferrous iron transmembrane transporter activity
CS032_RS09420	COG0477	Major facilitator Superfamily
CS032_RS09435	COG1924	4 iron, 4 sulfur cluster binding
CS032_RS09440	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
CS032_RS09445	COG2733	membrane
CS032_RS09450	COG2814	Major facilitator Superfamily
CS032_RS09475	COG0523	cobalamin synthesis protein
CS032_RS09480	COG2879	small protein
CS032_RS09485	COG1966	Carbon starvation protein
CS032_RS09495	COG0840	transmembrane signaling receptor activity
CS032_RS09500	COG2271	Major facilitator Superfamily
CS032_RS09510	COG1063	alcohol dehydrogenase
CS032_RS09525	COG1484	DNA-dependent DNA replication
CS032_RS09540	COG2966	Psort location CytoplasmicMembrane, score
CS032_RS09545	COG2197	response regulator
CS032_RS09550	COG2197	response regulator
CS032_RS09555	COG4114	ferric iron reductase
CS032_RS09585	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CS032_RS09590	COG0456	acetyltransferase
CS032_RS09595	COG1011	Hydrolase
CS032_RS09605	COG2823	Periplasmic or secreted lipoprotein
CS032_RS09615	COG4667	esterase of the alpha-beta hydrolase superfamily
CS032_RS09620	COG0084	hydrolase, TatD family'
CS032_RS09630	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CS032_RS09635	COG1328	CTP reductase activity
CS032_RS09670	COG3726	membrane protein affecting hemolysin expression
CS032_RS09675	COG0560	Phosphoserine phosphatase
CS032_RS09680	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CS032_RS09685	COG3172	ATPase kinase involved in NAD metabolism
CS032_RS09685	COG1056	cytidyltransferase-related domain
CS032_RS09690	COG0488	(ABC) transporter
CS032_RS09700	COG0741	lytic transglycosylase activity
CS032_RS09720	COG2207	Transcriptional regulator
CS032_RS09720	COG3708	Transcriptional regulator
CS032_RS09725	COG3045	CreA protein
CS032_RS09730	COG0745	RESPONSE REGULATOR receiver
CS032_RS09735	COG2205	protein histidine kinase activity
CS032_RS09740	COG4452	Inner membrane protein CreD
CS032_RS09745	COG0745	RESPONSE REGULATOR receiver
CS032_RS09755	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CS032_RS09765	COG0460	homoserine dehydrogenase
CS032_RS09765	COG0527	aspartate kinase activity
CS032_RS09775	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CS032_RS09790	COG1115	amino acid carrier protein
CS032_RS09800	COG0521	Mo-molybdopterin cofactor biosynthetic process
CS032_RS09805	COG1584	GPR1 FUN34 yaaH family protein
CS032_RS09810	COG4735	regulation of single-species biofilm formation
CS032_RS09855	COG0583	DNA-binding transcription factor activity
CS032_RS09885	COG0196	riboflavin kinase activity
CS032_RS09900	COG1047	Peptidyl-prolyl cis-trans
CS032_RS09920	COG0505	Belongs to the CarA family
CS032_RS09925	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CS032_RS09980	COG0644	oxidoreductase
CS032_RS09985	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CS032_RS09990	COG2271	Major facilitator Superfamily
CS032_RS10005	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CS032_RS10030	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CS032_RS10035	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CS032_RS10040	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CS032_RS10045	COG0564	pseudouridine synthase activity
CS032_RS10055	COG0417	DNA replication proofreading
CS032_RS10060	COG0235	Class ii aldolase
CS032_RS10080	COG4977	sequence-specific DNA binding
CS032_RS10085	COG0586	Pfam SNARE associated Golgi protein
CS032_RS10095	COG1178	ABC-type Fe3 transport system permease component
CS032_RS10100	COG4143	(ABC) transporter
CS032_RS10115	COG2814	Major facilitator Superfamily
CS032_RS10130	COG0473	3-isopropylmalate dehydrogenase activity
CS032_RS10145	COG0583	DNA-binding transcription factor activity
CS032_RS10155	COG0440	acetolactate synthase activity
CS032_RS10165	COG1609	Transcriptional regulator
CS032_RS10190	COG3116	cell division
CS032_RS10195	COG0768	penicillin binding
CS032_RS10200	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CS032_RS10205	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CS032_RS10215	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CS032_RS10220	COG0772	Belongs to the SEDS family
CS032_RS10235	COG1181	Belongs to the D-alanine--D-alanine ligase family
CS032_RS10240	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CS032_RS10245	COG0849	cell division
CS032_RS10250	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CS032_RS10270	COG0494	nUDIX hydrolase
CS032_RS10285	COG0237	dephospho-CoA kinase activity
CS032_RS10295	COG1459	type II secretion system
CS032_RS10300	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CS032_RS10305	COG4969	Belongs to the N-Me-Phe pilin family
CS032_RS10315	COG0157	Belongs to the NadC ModD family
CS032_RS10320	COG3023	N-Acetylmuramoyl-L-alanine amidase
CS032_RS10325	COG3725	Membrane protein required for beta-lactamase induction
CS032_RS10335	COG2186	Transcriptional regulator
CS032_RS10345	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CS032_RS10350	COG0508	dehydrogenase complex catalyzes the overall conversion of
CS032_RS10355	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CS032_RS10385	COG1049	propionate catabolic process, 2-methylcitrate cycle
CS032_RS10410	COG2132	Multicopper oxidase
CS032_RS10415	COG4993	Dehydrogenase
CS032_RS10515	COG4626	Terminase
CS032_RS10515	COG1802	Transcriptional regulator
CS032_RS10525	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CS032_RS10530	COG0288	reversible hydration of carbon dioxide
CS032_RS10535	COG1131	(ABC) transporter
CS032_RS10540	COG0842	Transport permease protein
CS032_RS10545	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CS032_RS10550	COG0726	polysaccharide deacetylase
CS032_RS10570	COG5464	transposase or invertase
CS032_RS10585	COG3539	Fimbrial protein
CS032_RS10590	COG3539	Fimbrial protein
CS032_RS10595	COG3539	Fimbrial protein
CS032_RS10600	COG3539	Fimbrial protein
CS032_RS10605	COG3188	usher protein
CS032_RS10610	COG3121	Chaperone
CS032_RS10615	COG3539	Fimbrial protein
CS032_RS10620	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CS032_RS10625	COG0617	tRNA 3'-terminal CCA addition
CS032_RS10635	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CS032_RS10645	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CS032_RS10650	COG1643	Atp-dependent helicase
CS032_RS10660	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CS032_RS10665	COG4774	siderophore transport
CS032_RS10670	COG1120	ATPase activity
CS032_RS10675	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CS032_RS10680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CS032_RS10700	COG2860	membrane
CS032_RS10705	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CS032_RS10725	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CS032_RS10730	COG3835	regulator
CS032_RS10740	COG1408	metallophosphoesterase
CS032_RS10755	COG0024	Methionine aminopeptidase
CS032_RS10790	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CS032_RS10795	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CS032_RS10800	COG0575	Belongs to the CDS family
CS032_RS10805	COG0750	zinc metalloprotease
CS032_RS10815	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CS032_RS10820	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CS032_RS10845	COG0587	DNA-directed DNA polymerase activity
CS032_RS10855	COG1982	Orn Lys Arg decarboxylase major
CS032_RS10860	COG0346	lactoylglutathione lyase activity
CS032_RS10870	COG4568	rho-dependent transcription termination
CS032_RS10880	COG4681	YaeQ
CS032_RS10885	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CS032_RS10890	COG3015	lipoprotein NlpE involved in copper resistance
CS032_RS10895	COG0791	NLP P60 protein
CS032_RS10905	COG1720	tRNA m6t6A37 methyltransferase activity
CS032_RS10915	COG1464	Belongs to the NlpA lipoprotein family
CS032_RS10920	COG2011	ABC-type metal ion transport system permease component
CS032_RS10925	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CS032_RS10930	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CS032_RS10965	COG0656	L-ascorbic acid biosynthetic process
CS032_RS10970	COG0583	DNA-binding transcription factor activity
CS032_RS10980	COG2226	methyltransferase
CS032_RS10985	COG1388	LysM domain
CS032_RS10985	COG0741	lytic transglycosylase activity
CS032_RS10995	COG2226	methyltransferase
CS032_RS11005	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CS032_RS11035	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CS032_RS11045	COG1960	acyl-CoA dehydrogenase activity
CS032_RS11055	COG0121	glutamine amidotransferase
CS032_RS11060	COG3034	peptidoglycan biosynthetic process
CS032_RS11065	COG3041	Addiction module toxin RelE StbE family
CS032_RS11070	COG3077	Addiction module antitoxin, RelB DinJ family
CS032_RS11075	COG0791	NLP P60 protein
CS032_RS11080	COG1943	Transposase
CS032_RS11100	COG2161	toxin-antitoxin pair type II binding
CS032_RS11110	COG0454	-acetyltransferase
CS032_RS11115	COG1690	Belongs to the RtcB family
CS032_RS11120	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CS032_RS11125	COG2195	Cleaves the N-terminal amino acid of tripeptides
CS032_RS11145	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CS032_RS11165	COG0582	viral genome integration into host DNA
CS032_RS11185	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CS032_RS11190	COG5532	Uncharacterized conserved protein (DUF2303)
CS032_RS11235	COG1846	Transcriptional regulator
CS032_RS11245	COG4725	Belongs to the MT-A70-like family
CS032_RS11255	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CS032_RS11265	COG1403	HNH endonuclease
CS032_RS11295	COG3772	lysozyme
CS032_RS11335	COG0740	serine-type endopeptidase activity
CS032_RS11410	COG5301	cellulose 1,4-beta-cellobiosidase activity
CS032_RS11415	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CS032_RS11435	COG4372	Transposase
CS032_RS11440	COG3436	PFAM IS66 Orf2 family protein
CS032_RS11520	COG0583	DNA-binding transcription factor activity
CS032_RS11525	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CS032_RS11530	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CS032_RS11535	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CS032_RS11540	COG2080	2 iron, 2 sulfur cluster binding
CS032_RS11560	COG0727	PFAM Uncharacterised protein family (UPF0153)
CS032_RS11565	COG3121	Chaperone
CS032_RS11575	COG3188	usher protein
CS032_RS11630	COG1388	LysM domain
CS032_RS11635	COG2207	Transcriptional regulator
CS032_RS11635	COG3708	Transcriptional regulator
CS032_RS11640	COG3059	membrane
CS032_RS11650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CS032_RS11655	COG2207	Transcriptional regulator
CS032_RS11660	COG0247	lactate metabolic process
CS032_RS11665	COG1139	Iron-sulfur cluster binding protein
CS032_RS11670	COG1556	Lactate utilization protein
CS032_RS11715	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CS032_RS11740	COG2200	EAL domain
CS032_RS11740	COG2771	luxR family
CS032_RS11745	COG0583	DNA-binding transcription factor activity
CS032_RS11760	COG0666	response to abiotic stimulus
CS032_RS11775	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CS032_RS11790	COG0549	Belongs to the carbamate kinase family
CS032_RS11795	COG0402	S-adenosylhomocysteine deaminase activity
CS032_RS11800	COG1064	alcohol dehydrogenase
CS032_RS11815	COG1280	lysine exporter protein (LysE YggA)
CS032_RS11825	COG3829	transcription factor binding
CS032_RS11830	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CS032_RS11835	COG0372	Belongs to the citrate synthase family
CS032_RS11840	COG2079	MmgE PrpD family protein
CS032_RS11845	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CS032_RS11850	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CS032_RS11855	COG0402	S-adenosylhomocysteine deaminase activity
CS032_RS11860	COG0583	DNA-binding transcription factor activity
CS032_RS11865	COG0288	reversible hydration of carbon dioxide
CS032_RS11875	COG2807	transmembrane transport
CS032_RS11880	COG0110	maltose O-acetyltransferase activity
CS032_RS11885	COG2223	nitrite transmembrane transporter activity
CS032_RS11890	COG3250	beta-galactosidase activity
CS032_RS11900	COG1609	Transcriptional regulator
CS032_RS11905	COG1414	Transcriptional regulator
CS032_RS11925	COG3971	2-oxopent-4-enoate hydratase activity
CS032_RS11940	COG2814	Major facilitator Superfamily
CS032_RS11945	COG3122	Protein conserved in bacteria
CS032_RS11975	COG1215	transferase activity, transferring glycosyl groups
CS032_RS11980	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CS032_RS12015	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CS032_RS12020	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CS032_RS12025	COG2175	clavaminate synthase activity
CS032_RS12030	COG0113	porphobilinogen synthase activity
CS032_RS12040	COG3468	outer membrane autotransporter barrel domain protein
CS032_RS12045	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CS032_RS12050	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CS032_RS12060	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CS032_RS12080	COG1181	Belongs to the D-alanine--D-alanine ligase family
CS032_RS12095	COG1785	Belongs to the alkaline phosphatase family
CS032_RS12105	COG3706	GGDEF domain
CS032_RS12110	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CS032_RS12135	COG4126	flavin adenine dinucleotide binding
CS032_RS12160	COG1940	carbohydrate kinase activity
CS032_RS12165	COG2814	Major facilitator Superfamily
CS032_RS12170	COG0419	ATPase involved in DNA repair
CS032_RS12175	COG0420	3'-5' exonuclease activity
CS032_RS12180	COG0745	RESPONSE REGULATOR receiver
CS032_RS12185	COG5002	protein histidine kinase activity
CS032_RS12190	COG1114	Component of the transport system for branched-chain amino acids
CS032_RS12195	COG1113	amino acid transport
CS032_RS12200	COG0366	Alpha amylase catalytic
CS032_RS12220	COG1862	Preprotein translocase
CS032_RS12225	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CS032_RS12230	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CS032_RS12235	COG1403	HNH endonuclease
CS032_RS12240	COG3248	Nucleoside-binding outer membrane protein
CS032_RS12250	COG4238	major outer membrane lipoprotein
CS032_RS12260	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CS032_RS12260	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CS032_RS12275	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CS032_RS12280	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CS032_RS12285	COG0667	Aldo Keto reductase
CS032_RS12295	COG0142	geranyltranstransferase activity
CS032_RS12310	COG0693	protein deglycase activity
CS032_RS12315	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CS032_RS12325	COG2814	Major facilitator Superfamily
CS032_RS12335	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CS032_RS12340	COG1845	cytochrome c oxidase, subunit III
CS032_RS12345	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CS032_RS12350	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CS032_RS12355	COG2223	nitrite transmembrane transporter activity
CS032_RS12360	COG3056	Lipoprotein
CS032_RS12370	COG0271	Belongs to the BolA IbaG family
CS032_RS12395	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CS032_RS12400	COG0776	regulation of translation
CS032_RS12405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CS032_RS12410	COG1555	photosystem II stabilization
CS032_RS12415	COG0824	Thioesterase
CS032_RS12425	COG4533	DNA binding
CS032_RS12435	COG1522	sequence-specific DNA binding
CS032_RS12440	COG1132	(ABC) transporter
CS032_RS12445	COG1132	(ABC) transporter
CS032_RS12450	COG0347	Belongs to the P(II) protein family
CS032_RS12455	COG0004	ammonium transporteR
CS032_RS12460	COG1946	Acyl-CoA thioesterase
CS032_RS12465	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CS032_RS12470	COG3695	enzyme binding
CS032_RS12480	COG5507	3-demethylubiquinone-9 3-methyltransferase
CS032_RS12485	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CS032_RS12495	COG0110	maltose O-acetyltransferase activity
CS032_RS12510	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CS032_RS12515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CS032_RS12520	COG1309	transcriptional regulator
CS032_RS12530	COG1196	nuclear chromosome segregation
CS032_RS12530	COG3264	Mechanosensitive ion channel
CS032_RS12540	COG3923	Primosomal replication protein n
CS032_RS12545	COG2832	Protein of unknown function (DUF454)
CS032_RS12560	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CS032_RS12600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CS032_RS12605	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CS032_RS12605	COG4651	solute:proton antiporter activity
CS032_RS12610	COG2223	nitrite transmembrane transporter activity
CS032_RS12620	COG0737	Belongs to the 5'-nucleotidase family
CS032_RS12625	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CS032_RS12635	COG3735	TraB family
CS032_RS12645	COG3093	addiction module antidote protein HigA
CS032_RS12650	COG2217	Heavy metal translocating P-type atpase
CS032_RS12655	COG2066	Belongs to the glutaminase family
CS032_RS12660	COG0531	amino acid
CS032_RS12665	COG0789	Transcriptional regulator
CS032_RS12670	COG1585	Membrane protein implicated in regulation of membrane protease activity
CS032_RS12675	COG0330	HflC and HflK could
CS032_RS12680	COG4619	ABC transporter
CS032_RS12685	COG0390	transport system, permease component
CS032_RS12690	COG3118	belongs to the thioredoxin family
CS032_RS12695	COG0300	oxidoreductase activity
CS032_RS12700	COG2755	lipolytic protein G-D-S-L family
CS032_RS12705	COG4181	ATPase activity
CS032_RS12740	COG0583	DNA-binding transcription factor activity
CS032_RS12750	COG1414	Transcriptional regulator
CS032_RS12755	COG3960	tartronate-semialdehyde synthase activity
CS032_RS12760	COG3622	Belongs to the hyi family
CS032_RS12765	COG2084	Dehydrogenase
CS032_RS12780	COG2233	PERMEase
CS032_RS12785	COG1929	Belongs to the glycerate kinase type-1 family
CS032_RS12790	COG3257	ureidoglycine aminohydrolase activity
CS032_RS12795	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CS032_RS12800	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CS032_RS12805	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CS032_RS12810	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CS032_RS12820	COG0549	Belongs to the carbamate kinase family
CS032_RS12825	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CS032_RS12830	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CS032_RS12845	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CS032_RS12855	COG1988	membrane-bound metal-dependent
CS032_RS12860	COG2501	S4 domain
CS032_RS12870	COG3539	Fimbrial protein
CS032_RS12875	COG3121	Chaperone
CS032_RS12880	COG3188	usher protein
CS032_RS12885	COG3539	Fimbrial protein
CS032_RS12890	COG3539	Fimbrial protein
CS032_RS12895	COG2197	response regulator
CS032_RS12910	COG2207	Transcriptional regulator
CS032_RS12925	COG4783	chaperone-mediated protein folding
CS032_RS12930	COG1215	transferase activity, transferring glycosyl groups
CS032_RS12935	COG5433	transposase activity
CS032_RS12970	COG3501	Rhs element vgr protein
CS032_RS12975	COG5002	protein histidine kinase activity
CS032_RS12980	COG0745	RESPONSE REGULATOR receiver
CS032_RS12990	COG1538	Outer membrane efflux protein
CS032_RS12995	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CS032_RS13000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CS032_RS13005	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CS032_RS13010	COG1113	amino acid transport
CS032_RS13015	COG0668	transmembrane transport
CS032_RS13020	COG0778	Nitroreductase
CS032_RS13025	COG2315	Protein conserved in bacteria
CS032_RS13065	COG2977	Belongs to the P-Pant transferase superfamily
CS032_RS13070	COG4771	TonB-dependent receptor
CS032_RS13075	COG2382	esterase
CS032_RS13080	COG3251	PFAM MbtH domain protein
CS032_RS13085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CS032_RS13085	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CS032_RS13090	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CS032_RS13095	COG1120	ATPase activity
CS032_RS13100	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CS032_RS13105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CS032_RS13115	COG4592	Periplasmic binding protein
CS032_RS13125	COG1169	isochorismate synthase
CS032_RS13135	COG3433	isochorismatase activity
CS032_RS13135	COG1535	isochorismatase
CS032_RS13140	COG1028	Short-chain dehydrogenase reductase Sdr
CS032_RS13145	COG2050	protein possibly involved in aromatic compounds catabolism
CS032_RS13150	COG1966	Carbon starvation protein
CS032_RS13155	COG2879	small protein
CS032_RS13160	COG0371	Dehydrogenase
CS032_RS13165	COG0436	Aminotransferase
CS032_RS13170	COG1475	DNA binding
CS032_RS13175	COG3969	phosphoadenosine phosphosulfate
CS032_RS13180	COG0583	DNA-binding transcription factor activity
CS032_RS13185	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CS032_RS13190	COG0450	alkyl hydroperoxide reductase
CS032_RS13195	COG3634	alkyl hydroperoxide reductase activity
CS032_RS13200	COG0589	response to stress
CS032_RS13205	COG1063	alcohol dehydrogenase
CS032_RS13215	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CS032_RS13225	COG3719	Belongs to the RNase T2 family
CS032_RS13230	COG0471	metal ion transport
CS032_RS13245	COG3051	citrate lyase alpha subunit
CS032_RS13250	COG2301	Belongs to the HpcH HpaI aldolase family
CS032_RS13260	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
CS032_RS13265	COG3290	protein histidine kinase activity
CS032_RS13270	COG4565	transcriptional regulatory protein
CS032_RS13275	COG3069	C4-dicarboxylate transmembrane transporter activity
CS032_RS13305	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CS032_RS13310	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CS032_RS13325	COG0583	DNA-binding transcription factor activity
CS032_RS13345	COG1686	Belongs to the peptidase S11 family
CS032_RS13350	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CS032_RS13355	COG0772	Belongs to the SEDS family
CS032_RS13360	COG0768	penicillin binding
CS032_RS13370	COG0799	negative regulation of ribosome biogenesis
CS032_RS13375	COG0406	alpha-ribazole phosphatase activity
CS032_RS13385	COG1466	dna polymerase III delta subunit
CS032_RS13400	COG2888	peptidyl-tyrosine sulfation
CS032_RS13405	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CS032_RS13415	COG2214	Heat shock protein DnaJ domain protein
CS032_RS13420	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CS032_RS13430	COG2214	Heat shock protein DnaJ domain protein
CS032_RS13435	COG0443	Heat shock 70 kDa protein
CS032_RS13445	COG1126	abc transporter atp-binding protein
CS032_RS13450	COG0765	amino acid transport
CS032_RS13455	COG0765	amino acid transport
CS032_RS13460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS032_RS13465	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CS032_RS13470	COG4535	Mg2 and Co2 transporter CorC
CS032_RS13480	COG1702	phosphate starvation-inducible protein PhoH
CS032_RS13490	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CS032_RS13535	COG0367	asparagine synthase
CS032_RS13545	COG0647	UMP catabolic process
CS032_RS13550	COG1846	Transcriptional regulator
CS032_RS13550	COG1940	carbohydrate kinase activity
CS032_RS13555	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CS032_RS13565	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CS032_RS13565	COG1263	PTS System
CS032_RS13565	COG2190	(PTS) system
CS032_RS13585	COG0735	belongs to the Fur family
CS032_RS13595	COG0716	FMN binding
CS032_RS13605	COG0596	Alpha beta hydrolase
CS032_RS13610	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CS032_RS13615	COG0033	Phosphoglucomutase
CS032_RS13635	COG0531	amino acid
CS032_RS13640	COG1982	Orn Lys Arg decarboxylase major
CS032_RS13650	COG0745	RESPONSE REGULATOR receiver
CS032_RS13655	COG2205	protein histidine kinase activity
CS032_RS13720	COG3272	Protein of unknown function (DUF1722)
CS032_RS13725	COG0415	Belongs to the DNA photolyase family
CS032_RS13730	COG3104	oligopeptide transport
CS032_RS13735	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CS032_RS13740	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CS032_RS13745	COG1984	allophanate hydrolase subunit 2
CS032_RS13760	COG3180	Ammonia monooxygenase
CS032_RS13765	COG3539	Fimbrial protein
CS032_RS13770	COG3121	Chaperone
CS032_RS13775	COG3188	usher protein
CS032_RS13780	COG3539	Fimbrial protein
CS032_RS13785	COG0372	Belongs to the citrate synthase family
CS032_RS13800	COG2009	succinate dehydrogenase
CS032_RS13805	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CS032_RS13810	COG1053	succinate dehydrogenase
CS032_RS13815	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CS032_RS13820	COG0567	Dehydrogenase, E1 component
CS032_RS13825	COG0508	dehydrogenase complex catalyzes the overall conversion of
CS032_RS13835	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CS032_RS13840	COG2188	Transcriptional regulator
CS032_RS13850	COG0383	alpha-mannosidase activity
CS032_RS13860	COG1271	oxidase subunit
CS032_RS13865	COG1294	oxidase, subunit
CS032_RS13870	COG4890	Cyd operon protein YbgT
CS032_RS13875	COG3790	cyd operon protein YbgE
CS032_RS13880	COG0824	Thioesterase
CS032_RS13885	COG0811	peptide transport
CS032_RS13890	COG0848	biopolymer transport protein
CS032_RS13895	COG3064	Membrane
CS032_RS13905	COG2885	chlorophyll binding
CS032_RS13910	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CS032_RS13955	COG3201	nicotinamide mononucleotide transporter
CS032_RS13960	COG1230	cation diffusion facilitator family transporter
CS032_RS13975	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CS032_RS13985	COG2017	converts alpha-aldose to the beta-anomer
CS032_RS13995	COG1085	galactose-1-phosphate uridylyltransferase
CS032_RS14000	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CS032_RS14005	COG1119	ATPase activity
CS032_RS14010	COG2005	Transcriptional regulator
CS032_RS14010	COG3585	molybdate ion transport
CS032_RS14025	COG0725	ABC transporter, periplasmic molybdate-binding protein
CS032_RS14030	COG4149	molybdate abc transporter
CS032_RS14035	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CS032_RS14040	COG0561	phosphatase activity
CS032_RS14050	COG0583	DNA-binding transcription factor activity
CS032_RS14055	COG2828	Protein conserved in bacteria
CS032_RS14060	COG0471	metal ion transport
CS032_RS14065	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CS032_RS14070	COG4677	pectinesterase activity
CS032_RS14075	COG0582	viral genome integration into host DNA
CS032_RS14270	COG3772	lysozyme
CS032_RS14290	COG3436	PFAM IS66 Orf2 family protein
CS032_RS14295	COG4372	Transposase
CS032_RS14305	COG5562	phage envelope protein
CS032_RS14315	COG4220	transposase activity
CS032_RS14385	COG1196	nuclear chromosome segregation
CS032_RS14420	COG5301	cellulose 1,4-beta-cellobiosidase activity
CS032_RS14450	COG2199	diguanylate cyclase activity
CS032_RS14460	COG1881	PFAM PEBP family protein
CS032_RS14465	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CS032_RS14480	COG2226	methyltransferase
CS032_RS14485	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CS032_RS14495	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CS032_RS14505	COG0521	Mo-molybdopterin cofactor biosynthetic process
CS032_RS14515	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CS032_RS14520	COG0314	molybdopterin synthase activity
CS032_RS14525	COG0670	Belongs to the BI1 family
CS032_RS14530	COG0670	Belongs to the BI1 family
CS032_RS14535	COG0392	lysyltransferase activity
CS032_RS14540	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CS032_RS14545	COG3568	Endonuclease Exonuclease Phosphatase
CS032_RS14555	COG0842	Transport permease protein
CS032_RS14560	COG0842	Transport permease protein
CS032_RS14565	COG1131	(ABC) transporter
CS032_RS14575	COG1309	transcriptional regulator
CS032_RS14580	COG0513	Belongs to the DEAD box helicase family
CS032_RS14585	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
CS032_RS14595	COG1199	ATP-dependent helicase activity
CS032_RS14600	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CS032_RS14605	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CS032_RS14615	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CS032_RS14625	COG4774	siderophore transport
CS032_RS14640	COG0668	transmembrane transport
CS032_RS14645	COG1126	abc transporter atp-binding protein
CS032_RS14650	COG0765	amino acid transport
CS032_RS14655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS032_RS14680	COG5006	permease, DMT superfamily
CS032_RS14685	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CS032_RS14690	COG2194	sulfuric ester hydrolase activity
CS032_RS14700	COG1321	iron dependent repressor
CS032_RS14705	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CS032_RS14710	COG1376	ErfK ybiS ycfS ynhG family protein
CS032_RS14715	COG0488	(ABC) transporter
CS032_RS14725	COG0561	phosphatase activity
CS032_RS14730	COG1882	Formate acetyltransferase
CS032_RS14735	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CS032_RS14740	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CS032_RS14745	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CS032_RS14750	COG0303	'Molybdopterin
CS032_RS14755	COG1446	asparaginase
CS032_RS14760	COG4172	Belongs to the ABC transporter superfamily
CS032_RS14765	COG0747	negative chemotaxis
CS032_RS14775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS032_RS14780	COG2200	EAL domain
CS032_RS14785	COG2199	diguanylate cyclase activity
CS032_RS14805	COG0625	glutathione transferase activity
CS032_RS14810	COG1686	Belongs to the peptidase S11 family
CS032_RS14815	COG1349	DNA-binding transcription factor activity
CS032_RS14820	COG0671	phosphoesterase, PA-phosphatase related
CS032_RS14825	COG2814	Major facilitator Superfamily
CS032_RS14835	COG0561	phosphatase activity
CS032_RS14840	COG0738	Major facilitator superfamily
CS032_RS14845	COG3226	Transcriptional regulator
CS032_RS14860	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CS032_RS14870	COG0778	Nitroreductase
CS032_RS14890	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CS032_RS14895	COG3842	ATPase activity
CS032_RS14900	COG1176	ABC-type spermidine putrescine transport system, permease component I
CS032_RS14905	COG1177	transmembrane transport
CS032_RS14920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS032_RS14925	COG4160	amino acid transport
CS032_RS14930	COG4215	(ABC) transporter
CS032_RS14935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS032_RS14940	COG1126	abc transporter atp-binding protein
CS032_RS14955	COG3023	N-Acetylmuramoyl-L-alanine amidase
CS032_RS14960	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CS032_RS14965	COG0702	epimerase
CS032_RS14970	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CS032_RS14975	COG0028	Belongs to the TPP enzyme family
CS032_RS14980	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CS032_RS14990	COG2431	L-lysine efflux transmembrane transporter activity
CS032_RS15010	COG2990	Protein conserved in bacteria
CS032_RS15015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CS032_RS15020	COG0577	efflux transmembrane transporter activity
CS032_RS15020	COG1136	(ABC) transporter
CS032_RS15025	COG1278	Cold shock
CS032_RS15035	COG0542	response to heat
CS032_RS15060	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CS032_RS15065	COG4988	ABC transporter
CS032_RS15070	COG0492	ferredoxin-NADP+ reductase activity
CS032_RS15080	COG1522	sequence-specific DNA binding
CS032_RS15085	COG1178	ABC-type Fe3 transport system permease component
CS032_RS15085	COG1674	ftsk spoiiie
CS032_RS15095	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CS032_RS15105	COG0243	molybdopterin cofactor binding
CS032_RS15110	COG0437	4 iron, 4 sulfur cluster binding
CS032_RS15115	COG3302	dmso reductase anchor subunit
CS032_RS15120	COG1335	isochorismatase
CS032_RS15130	COG0531	amino acid
CS032_RS15135	COG0583	DNA-binding transcription factor activity
CS032_RS15140	COG2249	NAD(P)H dehydrogenase (quinone) activity
CS032_RS15145	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CS032_RS15150	COG1882	Formate acetyltransferase
CS032_RS15155	COG2116	formate transmembrane transporter activity
CS032_RS15160	COG1944	ATP diphosphatase activity
CS032_RS15165	COG2323	membrane
CS032_RS15180	COG0501	Belongs to the peptidase M48B family
CS032_RS15190	COG0539	negative regulation of cytoplasmic translation
CS032_RS15200	COG2333	competence protein COMEC
CS032_RS15200	COG0658	competence protein
CS032_RS15205	COG1132	(ABC) transporter
CS032_RS15210	COG1663	tetraacyldisaccharide 4'-kinase activity
CS032_RS15215	COG3214	Protein conserved in bacteria
CS032_RS15230	COG3173	Aminoglycoside phosphotransferase
CS032_RS15235	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CS032_RS15245	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CS032_RS15255	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CS032_RS15275	COG3108	Peptidase M15
CS032_RS15280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CS032_RS15285	COG1448	Aminotransferase
CS032_RS15305	COG0308	aminopeptidase N
CS032_RS15310	COG1116	anion transmembrane transporter activity
CS032_RS15315	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CS032_RS15325	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CS032_RS15330	COG0431	NADPH-dependent FMN reductase
CS032_RS15350	COG3539	Fimbrial protein
CS032_RS15355	COG3539	Fimbrial protein
CS032_RS15360	COG3121	Chaperone
CS032_RS15375	COG0633	Ferredoxin
CS032_RS15375	COG3217	Mosc domain protein beta barrel domain protein
CS032_RS15385	COG0488	(ABC) transporter
CS032_RS15390	COG2995	paraquat-inducible protein a
CS032_RS15395	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CS032_RS15395	COG3008	intermembrane lipid transfer
CS032_RS15400	COG3009	Protein conserved in bacteria
CS032_RS15405	COG3130	regulation of translation
CS032_RS15415	COG1067	ATP-dependent peptidase activity
CS032_RS15425	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CS032_RS15425	COG2885	chlorophyll binding
CS032_RS15440	COG3070	regulator of competence-specific genes
CS032_RS15445	COG1289	transmembrane transporter activity
CS032_RS15450	COG3304	Inner membrane component domain
CS032_RS15455	COG0210	DNA helicase
CS032_RS15470	COG1832	CoA-binding protein
CS032_RS15485	COG1254	Belongs to the acylphosphatase family
CS032_RS15490	COG2920	part of a sulfur-relay system
CS032_RS15495	COG0670	Belongs to the BI1 family
CS032_RS15505	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CS032_RS15510	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CS032_RS15515	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
CS032_RS15520	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CS032_RS15525	COG1999	signal sequence binding
CS032_RS15530	COG1773	rubredoxin
CS032_RS15535	COG1271	oxidase subunit
CS032_RS15540	COG1294	oxidase, subunit
CS032_RS15560	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CS032_RS15565	COG1596	polysaccharide export
CS032_RS15570	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CS032_RS15595	COG1278	Cold shock
CS032_RS15600	COG1278	Cold shock
CS032_RS15620	COG0348	domain, Protein
CS032_RS15625	COG0784	Response regulator, receiver
CS032_RS15625	COG2198	Histidine kinase
CS032_RS15625	COG2205	protein histidine kinase activity
CS032_RS15630	COG1879	ABC-type sugar transport system periplasmic component
CS032_RS15635	COG0745	RESPONSE REGULATOR receiver
CS032_RS15640	COG3005	denitrification pathway
CS032_RS15645	COG0243	molybdopterin cofactor binding
CS032_RS15650	COG3381	protein complex oligomerization
CS032_RS15690	COG3729	General stress protein
CS032_RS15695	COG2233	PERMEase
CS032_RS15730	COG1309	transcriptional regulator
CS032_RS15735	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CS032_RS15735	COG0506	proline dehydrogenase activity
CS032_RS15735	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CS032_RS15750	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CS032_RS15770	COG2822	iron ion transport
CS032_RS15775	COG2837	iron assimilation
CS032_RS15785	COG1702	phosphate starvation-inducible protein PhoH
CS032_RS15790	COG3658	cytochrome
CS032_RS15795	COG1215	transferase activity, transferring glycosyl groups
CS032_RS15800	COG0726	polysaccharide deacetylase
CS032_RS15800	COG1649	PFAM Uncharacterised BCR, COG1649
CS032_RS15815	COG0457	Tetratricopeptide repeat
CS032_RS15830	COG3706	GGDEF domain
CS032_RS15870	COG3381	protein complex oligomerization
CS032_RS15880	COG1462	curli production assembly transport component CsgG
CS032_RS15895	COG2197	response regulator
CS032_RS15930	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CS032_RS15935	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CS032_RS15960	COG2943	transferase activity, transferring hexosyl groups
CS032_RS15965	COG5645	(Lipo)protein
CS032_RS15980	COG1560	Kdo2-lipid A biosynthetic process
CS032_RS15990	COG2353	YceI-like domain
CS032_RS15995	COG3038	cytochrome b561
CS032_RS16035	COG2999	glutathione oxidoreductase activity
CS032_RS16045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CS032_RS16055	COG0673	inositol 2-dehydrogenase activity
CS032_RS16060	COG0728	peptidoglycan biosynthetic process
CS032_RS16065	COG3418	PFAM FlgN family protein
CS032_RS16070	COG2747	anti-sigma28 factor FlgM
CS032_RS16075	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
CS032_RS16080	COG1815	bacterial-type flagellum-dependent cell motility
CS032_RS16085	COG1558	bacterial-type flagellum-dependent cell motility
CS032_RS16090	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CS032_RS16095	COG1749	Flagellar hook protein flgE
CS032_RS16100	COG4787	bacterial-type flagellum-dependent cell motility
CS032_RS16105	COG4786	Flagellar basal body rod
CS032_RS16120	COG3951	Flagellar rod assembly protein muramidase FlgJ
CS032_RS16120	COG1705	Flagellar rod assembly protein muramidase FlgJ
CS032_RS16125	COG1256	bacterial-type flagellum assembly
CS032_RS16130	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CS032_RS16135	COG1530	ribonuclease E activity
CS032_RS16145	COG0564	pseudouridine synthase activity
CS032_RS16150	COG0424	maF-like protein
CS032_RS16155	COG1399	metal-binding, possibly nucleic acid-binding protein
CS032_RS16175	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CS032_RS16180	COG1028	Short-chain dehydrogenase reductase Sdr
CS032_RS16190	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CS032_RS16195	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CS032_RS16200	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CS032_RS16210	COG0470	DNA polymerase III
CS032_RS16215	COG0084	hydrolase, TatD family'
CS032_RS16220	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CS032_RS16220	COG1263	PTS System
CS032_RS16225	COG4773	Receptor
CS032_RS16230	COG0537	adenosine 5'-monophosphoramidase activity
CS032_RS16235	COG5633	Lipoprotein
CS032_RS16240	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
CS032_RS16265	COG1252	NADH dehydrogenase
CS032_RS16270	COG3134	Outer membrane lipoprotein
CS032_RS16275	COG1309	transcriptional regulator
CS032_RS16285	COG1376	ErfK ybiS ycfS ynhG family protein
CS032_RS16285	COG1388	LysM domain
CS032_RS16290	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CS032_RS16295	COG4763	Acyl-transferase
CS032_RS16300	COG4591	ABC-type transport system involved in lipoprotein release permease component
CS032_RS16305	COG1136	(ABC) transporter
CS032_RS16310	COG4591	ABC-type transport system involved in lipoprotein release permease component
CS032_RS16320	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CS032_RS16325	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CS032_RS16335	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CS032_RS16340	COG1177	transmembrane transport
CS032_RS16345	COG0582	viral genome integration into host DNA
CS032_RS16355	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CS032_RS16415	COG1846	Transcriptional regulator
CS032_RS16420	COG1484	DNA-dependent DNA replication
CS032_RS16470	COG1403	HNH endonuclease
CS032_RS16475	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CS032_RS16555	COG4626	Terminase
CS032_RS16555	COG1802	Transcriptional regulator
CS032_RS16565	COG4695	Portal protein
CS032_RS16610	COG4386	tail sheath protein
CS032_RS16660	COG5301	cellulose 1,4-beta-cellobiosidase activity
CS032_RS16665	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CS032_RS16675	COG0500	methyltransferase
CS032_RS16690	COG3842	ATPase activity
CS032_RS16705	COG2850	peptidyl-arginine hydroxylation
CS032_RS16710	COG2205	protein histidine kinase activity
CS032_RS16715	COG0745	RESPONSE REGULATOR receiver
CS032_RS16720	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CS032_RS16740	COG1187	pseudouridine synthase activity
CS032_RS16745	COG0538	isocitrate dehydrogenase activity
CS032_RS16760	COG2200	EAL domain
CS032_RS16825	COG2894	cell division
CS032_RS16860	COG0179	Fumarylacetoacetate (FAA) hydrolase
CS032_RS16885	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CS032_RS16890	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CS032_RS16895	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CS032_RS16920	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CS032_RS16935	COG1619	proteins homologs of microcin C7 resistance protein MccF
CS032_RS16950	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CS032_RS16955	COG2261	transglycosylase associated protein
CS032_RS16975	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CS032_RS16975	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CS032_RS16975	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CS032_RS16980	COG1461	Dihydroxyacetone kinase
CS032_RS16985	COG2376	Dihydroxyacetone kinase
CS032_RS16990	COG3284	Transcriptional regulator
CS032_RS16995	COG3468	outer membrane autotransporter barrel domain protein
CS032_RS17015	COG0012	GTP binding
CS032_RS17030	COG0659	secondary active sulfate transmembrane transporter activity
CS032_RS17040	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CS032_RS17070	COG2890	protein-(glutamine-N5) methyltransferase activity
CS032_RS17075	COG3094	Invasion gene expression up-regulator, SirB
CS032_RS17080	COG2912	Transglutaminase-like superfamily
CS032_RS17110	COG0387	Pfam Sodium calcium exchanger
CS032_RS17115	COG4572	Cation transport regulator
CS032_RS17120	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CS032_RS17125	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CS032_RS17130	COG4932	domain protein
CS032_RS17135	COG2197	response regulator
CS032_RS17140	COG3850	Histidine kinase
CS032_RS17150	COG2223	nitrite transmembrane transporter activity
CS032_RS17155	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CS032_RS17160	COG1140	nitrate reductase beta subunit
CS032_RS17165	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CS032_RS17170	COG2181	nitrate reductase activity
CS032_RS17210	COG0788	formyltetrahydrofolate deformylase activity
CS032_RS17220	COG1752	Esterase of the alpha-beta hydrolase superfamily
CS032_RS17225	COG0745	RESPONSE REGULATOR receiver
CS032_RS17230	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CS032_RS17240	COG1435	thymidine kinase activity
CS032_RS17245	COG1454	alcohol dehydrogenase
CS032_RS17245	COG1012	belongs to the aldehyde dehydrogenase family
CS032_RS17250	COG2095	MarC family integral membrane protein
CS032_RS17260	COG4166	transmembrane transport
CS032_RS17265	COG0601	transmembrane transport
CS032_RS17270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS032_RS17275	COG0444	Belongs to the ABC transporter superfamily
CS032_RS17280	COG4608	Belongs to the ABC transporter superfamily
CS032_RS17305	COG2350	Protein conserved in bacteria
CS032_RS17310	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CS032_RS17315	COG1607	acyl-coa hydrolase
CS032_RS17335	COG3047	cAMP biosynthetic process
CS032_RS17340	COG0582	viral genome integration into host DNA
CS032_RS17350	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CS032_RS17425	COG3436	PFAM IS66 Orf2 family protein
CS032_RS17430	COG4372	Transposase
CS032_RS17460	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CS032_RS17465	COG0484	heat shock protein binding
CS032_RS17515	COG3772	lysozyme
CS032_RS17640	COG5301	cellulose 1,4-beta-cellobiosidase activity
CS032_RS17645	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CS032_RS17655	COG0500	methyltransferase
CS032_RS17670	COG3685	Protein conserved in bacteria
CS032_RS17675	COG3685	Protein conserved in bacteria
CS032_RS17680	COG3729	General stress protein
CS032_RS17695	COG0135	phosphoribosylanthranilate isomerase activity
CS032_RS17695	COG0134	indole-3-glycerol-phosphate synthase activity
CS032_RS17700	COG0512	Glutamine amidotransferase of anthranilate synthase
CS032_RS17700	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CS032_RS17705	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CS032_RS17715	COG0613	PHP domain protein
CS032_RS17720	COG0009	L-threonylcarbamoyladenylate synthase
CS032_RS17725	COG4907	membrane protein (DUF2207)
CS032_RS17730	COG1187	pseudouridine synthase activity
CS032_RS17735	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CS032_RS17740	COG1028	Short-chain dehydrogenase reductase Sdr
CS032_RS17745	COG0616	signal peptide processing
CS032_RS17760	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CS032_RS17770	COG0583	DNA-binding transcription factor activity
CS032_RS17790	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CS032_RS17800	COG0671	phosphoesterase, PA-phosphatase related
CS032_RS17805	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CS032_RS17810	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CS032_RS17820	COG0023	Translation Initiation Factor
CS032_RS17830	COG1349	DNA-binding transcription factor activity
CS032_RS17840	COG5001	Diguanylate cyclase
CS032_RS17855	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CS032_RS17855	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CS032_RS17860	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CS032_RS17870	COG2852	Protein conserved in bacteria
CS032_RS17875	COG4172	Belongs to the ABC transporter superfamily
CS032_RS17880	COG4172	Belongs to the ABC transporter superfamily
CS032_RS17885	COG4171	peptide transport system, permease
CS032_RS17890	COG4168	peptide transport system, permease
CS032_RS17895	COG4166	transmembrane transport
CS032_RS17910	COG0531	amino acid
CS032_RS17915	COG0174	glutamine synthetase
CS032_RS17920	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CS032_RS17925	COG1396	sequence-specific DNA binding
CS032_RS17925	COG1917	Cupin 2, conserved barrel domain protein
CS032_RS17935	COG1012	belongs to the aldehyde dehydrogenase family
CS032_RS17940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CS032_RS17945	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CS032_RS17950	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CS032_RS17955	COG1842	Phage shock protein A
CS032_RS17965	COG1983	PspC domain protein
CS032_RS17975	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CS032_RS17985	COG1653	transport
CS032_RS17990	COG1175	transmembrane transport
CS032_RS17995	COG0395	ABC-type sugar transport system, permease component
CS032_RS18000	COG1063	alcohol dehydrogenase
CS032_RS18020	COG3106	COG3106 Predicted ATPase
CS032_RS18030	COG3283	Transcriptional regulator of aromatic amino acids metabolism
CS032_RS18035	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CS032_RS18040	COG4948	Mandelate Racemase Muconate Lactonizing
CS032_RS18045	COG2866	Carboxypeptidase
CS032_RS18050	COG0702	epimerase
CS032_RS18055	COG1073	alpha beta
CS032_RS18060	COG0583	DNA-binding transcription factor activity
CS032_RS18065	COG4166	transmembrane transport
CS032_RS18070	COG0668	transmembrane transport
CS032_RS18075	COG3182	Iron-regulated membrane protein
CS032_RS18080	COG0589	response to stress
CS032_RS18085	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CS032_RS18090	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CS032_RS18095	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CS032_RS18105	COG1473	amidohydrolase
CS032_RS18110	COG1473	amidohydrolase
CS032_RS18115	COG0583	DNA-binding transcription factor activity
CS032_RS18125	COG2840	Smr protein MutS2
CS032_RS18130	COG3706	GGDEF domain
CS032_RS18145	COG0513	Belongs to the DEAD box helicase family
CS032_RS18155	COG0589	response to stress
CS032_RS18160	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CS032_RS18170	COG1013	pyruvate-flavodoxin oxidoreductase activity
CS032_RS18170	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CS032_RS18170	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CS032_RS18170	COG0674	pyruvate-flavodoxin oxidoreductase activity
CS032_RS18175	COG3042	response to heat
CS032_RS18180	COG3187	Heat shock protein
CS032_RS18185	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CS032_RS18190	COG2911	Protein conserved in bacteria
CS032_RS18200	COG3784	Protein of unknown function (DUF1318)
CS032_RS18205	COG2207	Transcriptional regulator
CS032_RS18210	COG1012	belongs to the aldehyde dehydrogenase family
CS032_RS18230	COG2030	dehydratase
CS032_RS18230	COG1012	belongs to the aldehyde dehydrogenase family
CS032_RS18235	COG3396	Phenylacetate-CoA oxygenase
CS032_RS18240	COG3460	Phenylacetate-CoA oxygenase
CS032_RS18245	COG3396	Phenylacetate-CoA oxygenase
CS032_RS18250	COG2151	metal-sulfur cluster biosynthetic enzyme
CS032_RS18255	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CS032_RS18260	COG1024	Enoyl-CoA hydratase
CS032_RS18270	COG1250	3-hydroxyacyl-CoA dehydrogenase
CS032_RS18280	COG0183	Belongs to the thiolase family
CS032_RS18285	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CS032_RS18290	COG3327	negative regulation of DNA-templated transcription, initiation
CS032_RS18295	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CS032_RS18330	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CS032_RS18335	COG4589	Belongs to the CDS family
CS032_RS18340	COG2267	carboxylic ester hydrolase activity
CS032_RS18345	COG2453	phosphatase
CS032_RS18345	COG0671	phosphoesterase, PA-phosphatase related
CS032_RS18355	COG1643	Atp-dependent helicase
CS032_RS18360	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CS032_RS18365	COG1012	belongs to the aldehyde dehydrogenase family
CS032_RS18370	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CS032_RS18375	COG3038	cytochrome b561
CS032_RS18390	COG0840	transmembrane signaling receptor activity
CS032_RS18395	COG0583	DNA-binding transcription factor activity
CS032_RS18400	COG5383	Protein conserved in bacteria
CS032_RS18420	COG2841	Protein conserved in bacteria
CS032_RS18425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CS032_RS18430	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CS032_RS18435	COG1275	C4-dicarboxylate transporter malic acid transport protein
CS032_RS18440	COG0500	methyltransferase
CS032_RS18460	COG3135	benzoate transporter
CS032_RS18465	COG1396	sequence-specific DNA binding
CS032_RS18470	COG0826	peptidase U32
CS032_RS18480	COG1724	mRNA binding
CS032_RS18485	COG1598	PFAM Uncharacterised protein family UPF0150
CS032_RS18490	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CS032_RS18495	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CS032_RS18500	COG3842	ATPase activity
CS032_RS18505	COG1176	ABC-type spermidine putrescine transport system, permease component I
CS032_RS18510	COG1177	transmembrane transport
CS032_RS18540	COG3238	Protein conserved in bacteria
CS032_RS18545	COG1247	-acetyltransferase
CS032_RS18555	COG2130	NADP-dependent
CS032_RS18560	COG1802	Transcriptional regulator
CS032_RS18565	COG4772	TonB-dependent receptor
CS032_RS18580	COG3391	amine dehydrogenase activity
CS032_RS18585	COG1113	amino acid transport
CS032_RS18590	COG0625	glutathione transferase activity
CS032_RS18610	COG3209	COG3209 Rhs family protein
CS032_RS18640	COG5433	transposase activity
CS032_RS18650	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CS032_RS18655	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CS032_RS18660	COG0384	phenazine biosynthesis protein PhzF
CS032_RS18665	COG2181	nitrate reductase activity
CS032_RS18670	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CS032_RS18675	COG1140	nitrate reductase beta subunit
CS032_RS18680	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CS032_RS18685	COG2223	nitrite transmembrane transporter activity
CS032_RS18695	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CS032_RS18700	COG0697	spore germination
CS032_RS18705	COG3383	formate dehydrogenase (NAD+) activity
CS032_RS18705	COG0243	molybdopterin cofactor binding
CS032_RS18710	COG0243	molybdopterin cofactor binding
CS032_RS18710	COG3383	formate dehydrogenase (NAD+) activity
CS032_RS18715	COG0437	4 iron, 4 sulfur cluster binding
CS032_RS18720	COG2864	formate dehydrogenase
CS032_RS18725	COG3093	addiction module antidote protein HigA
CS032_RS18730	COG1064	alcohol dehydrogenase
CS032_RS18755	COG1764	response to oxidative stress
CS032_RS18760	COG4608	Belongs to the ABC transporter superfamily
CS032_RS18765	COG0444	Belongs to the ABC transporter superfamily
CS032_RS18770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS032_RS18775	COG0601	transmembrane transport
CS032_RS18780	COG0747	negative chemotaxis
CS032_RS18785	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CS032_RS18800	COG1649	PFAM Uncharacterised BCR, COG1649
CS032_RS18805	COG0531	amino acid
CS032_RS18810	COG0076	glutamate decarboxylase activity
CS032_RS18815	COG0612	Peptidase, M16
CS032_RS18820	COG4771	TonB-dependent receptor
CS032_RS18825	COG4178	(ABC) transporter
CS032_RS18830	COG0641	radical SAM
CS032_RS18835	COG3119	arylsulfatase activity
CS032_RS18840	COG2207	Transcriptional regulator
CS032_RS18850	COG0243	molybdopterin cofactor binding
CS032_RS18865	COG3550	peptidyl-serine autophosphorylation
CS032_RS18870	COG1396	sequence-specific DNA binding
CS032_RS18880	COG3210	domain, Protein
CS032_RS18880	COG2911	Protein conserved in bacteria
CS032_RS18935	COG3781	membrane
CS032_RS18955	COG2199	diguanylate cyclase activity
CS032_RS18970	COG2066	Belongs to the glutaminase family
CS032_RS18975	COG1012	belongs to the aldehyde dehydrogenase family
CS032_RS18980	COG0583	DNA-binding transcription factor activity
CS032_RS19010	COG1846	Transcriptional regulator
CS032_RS19015	COG4977	sequence-specific DNA binding
CS032_RS19025	COG0697	spore germination
CS032_RS19030	COG2814	Major facilitator Superfamily
CS032_RS19040	COG3706	GGDEF domain
CS032_RS19045	COG3111	PFAM Bacterial OB fold (BOF) protein
CS032_RS19050	COG1546	Belongs to the CinA family
CS032_RS19055	COG0339	signal peptide processing
CS032_RS19060	COG4221	oxidoreductase activity
CS032_RS19065	COG1802	Transcriptional regulator
CS032_RS19075	COG0246	Mannitol dehydrogenase
CS032_RS19080	COG0477	Major facilitator Superfamily
CS032_RS19085	COG1063	alcohol dehydrogenase
CS032_RS19090	COG4948	Mandelate Racemase Muconate Lactonizing
CS032_RS19110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CS032_RS19125	COG0243	molybdopterin cofactor binding
CS032_RS19130	COG0243	molybdopterin cofactor binding
CS032_RS19135	COG0437	4 iron, 4 sulfur cluster binding
CS032_RS19140	COG3302	dmso reductase anchor subunit
CS032_RS19145	COG3381	protein complex oligomerization
CS032_RS19155	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CS032_RS19160	COG1940	carbohydrate kinase activity
CS032_RS19165	COG0583	DNA-binding transcription factor activity
CS032_RS19195	COG3591	Belongs to the peptidase S1B family
CS032_RS19215	COG0628	permease
CS032_RS19220	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CS032_RS19225	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CS032_RS19240	COG0531	amino acid
CS032_RS19250	COG3136	membrane protein required for alginate biosynthesis
CS032_RS19255	COG0745	RESPONSE REGULATOR receiver
CS032_RS19260	COG2205	protein histidine kinase activity
CS032_RS19270	COG0114	fumarate hydratase activity
CS032_RS19275	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CS032_RS19275	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CS032_RS19280	COG1482	cell wall glycoprotein biosynthetic process
CS032_RS19285	COG5339	Protein conserved in bacteria
CS032_RS19300	COG3250	beta-galactosidase activity
CS032_RS19305	COG1309	transcriptional regulator
CS032_RS19310	COG1028	Short-chain dehydrogenase reductase Sdr
CS032_RS19315	COG1609	Transcriptional regulator
CS032_RS19320	COG1263	PTS System
CS032_RS19320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CS032_RS19325	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CS032_RS19335	COG0673	inositol 2-dehydrogenase activity
CS032_RS19380	COG4659	FMN binding
CS032_RS19390	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CS032_RS19400	COG3104	oligopeptide transport
CS032_RS19405	COG0625	glutathione transferase activity
CS032_RS19410	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CS032_RS19425	COG3895	Periplasmic Protein
CS032_RS19435	COG3133	Outer membrane lipoprotein
CS032_RS19455	COG1289	transmembrane transporter activity
CS032_RS19460	COG2032	superoxide dismutase activity
CS032_RS19465	COG4989	oxidoreductase activity
CS032_RS19470	COG3313	Fe-S protein
CS032_RS19475	COG1309	transcriptional regulator
CS032_RS19480	COG1902	pentaerythritol trinitrate reductase activity
CS032_RS19485	COG0346	lactoylglutathione lyase activity
CS032_RS19490	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CS032_RS19500	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CS032_RS19505	COG0791	NLP P60 protein
CS032_RS19510	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CS032_RS19515	COG2814	Major facilitator Superfamily
CS032_RS19535	COG0583	DNA-binding transcription factor activity
CS032_RS19540	COG2814	Major facilitator Superfamily
CS032_RS19545	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CS032_RS19550	COG0307	riboflavin synthase, alpha
CS032_RS19560	COG3468	outer membrane autotransporter barrel domain protein
CS032_RS19580	COG4529	Protein conserved in bacteria
CS032_RS19590	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
CS032_RS19595	COG0437	4 iron, 4 sulfur cluster binding
CS032_RS19605	COG2414	aldehyde ferredoxin oxidoreductase
CS032_RS19610	COG0437	4 iron, 4 sulfur cluster binding
CS032_RS19620	COG0469	pyruvate kinase activity
CS032_RS19625	COG4238	major outer membrane lipoprotein
CS032_RS19630	COG1376	ErfK ybiS ycfS ynhG family protein
CS032_RS19645	COG0719	Fe-S assembly protein
CS032_RS19650	COG0396	ATPase activity
CS032_RS19655	COG0719	Fe-S assembly protein
CS032_RS19660	COG0316	Belongs to the HesB IscA family
CS032_RS19670	COG2050	protein possibly involved in aromatic compounds catabolism
CS032_RS19675	COG0247	lactate metabolic process
CS032_RS19675	COG0277	FAD linked oxidase domain protein
CS032_RS19685	COG0628	permease
CS032_RS19715	COG2271	Major facilitator Superfamily
CS032_RS19730	COG4670	ketone body catabolic process
CS032_RS19735	COG1960	acyl-CoA dehydrogenase activity
CS032_RS19740	COG1917	Cupin 2, conserved barrel domain protein
CS032_RS19740	COG2207	Transcriptional regulator
CS032_RS19750	COG2086	electron transfer activity
CS032_RS19755	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CS032_RS19760	COG0644	oxidoreductase
CS032_RS19765	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CS032_RS19770	COG0318	PFAM AMP-dependent synthetase and ligase
CS032_RS19775	COG0574	Belongs to the PEP-utilizing enzyme family
CS032_RS19775	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CS032_RS19790	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CS032_RS19795	COG4256	Hemin uptake protein
CS032_RS19805	COG2200	EAL domain
CS032_RS19810	COG0791	NLP P60 protein
CS032_RS19820	COG0386	Belongs to the glutathione peroxidase family
CS032_RS19835	COG0072	phenylalanine-tRNA ligase activity
CS032_RS19835	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CS032_RS19885	COG3137	Salt-induced outer membrane protein
CS032_RS19890	COG1105	Belongs to the carbohydrate kinase PfkB family
CS032_RS19900	COG3001	Fructosamine kinase
CS032_RS19910	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CS032_RS19915	COG1988	membrane-bound metal-dependent
CS032_RS19920	COG1823	symporter activity
CS032_RS19935	COG0753	catalase activity
CS032_RS19945	COG1486	melibiose metabolic process
CS032_RS19950	COG1917	Cupin 2, conserved barrel domain protein
CS032_RS19950	COG2169	Transcriptional regulator
CS032_RS19955	COG1447	Phosphotransferase system cellobiose-specific component IIA
CS032_RS19970	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CS032_RS19980	COG0322	excinuclease ABC activity
CS032_RS19990	COG3678	ATP-independent chaperone mediated protein folding
CS032_RS20025	COG0708	Exodeoxyribonuclease III
CS032_RS20030	COG0398	Pfam SNARE associated Golgi protein
CS032_RS20040	COG0398	Pfam SNARE associated Golgi protein
CS032_RS20045	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CS032_RS20050	COG4134	Bacterial extracellular solute-binding protein
CS032_RS20055	COG4135	transport system, permease component
CS032_RS20060	COG4136	ATPase activity
CS032_RS20065	COG2897	thiosulfate sulfurtransferase activity
CS032_RS20070	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CS032_RS20075	COG0494	nUDIX hydrolase
CS032_RS20085	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CS032_RS20095	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CS032_RS20110	COG0778	Nitroreductase
CS032_RS20120	COG0616	signal peptide processing
CS032_RS20125	COG0252	asparaginase activity
CS032_RS20130	COG1335	isochorismatase
CS032_RS20140	COG1349	DNA-binding transcription factor activity
CS032_RS20145	COG0667	Aldo Keto reductase
CS032_RS20150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CS032_RS20155	COG0191	fructose-bisphosphate aldolase activity
CS032_RS20160	COG1063	alcohol dehydrogenase
CS032_RS20170	COG2271	Major facilitator Superfamily
CS032_RS20175	COG1063	alcohol dehydrogenase
CS032_RS20180	COG3139	Protein of unknown function (DUF1315)
CS032_RS20190	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CS032_RS20195	COG0676	glucose-6-phosphate 1-epimerase activity
CS032_RS20205	COG3713	MltA-interacting MipA family protein
CS032_RS20210	COG2766	serine protein kinase
CS032_RS20230	COG2199	diguanylate cyclase activity
CS032_RS20235	COG2199	diguanylate cyclase activity
CS032_RS20255	COG2207	Transcriptional regulator
CS032_RS20260	COG2807	transmembrane transport
CS032_RS20275	COG3189	MarR family transcriptional regulator
CS032_RS20280	COG3042	response to heat
CS032_RS20300	COG2261	transglycosylase associated protein
CS032_RS20310	COG3615	Tellurite resistance protein tehB
CS032_RS20320	COG0583	DNA-binding transcription factor activity
CS032_RS20325	COG0473	3-isopropylmalate dehydrogenase activity
CS032_RS20330	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CS032_RS20335	COG4638	Rieske (2fe-2S)
CS032_RS20340	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CS032_RS20345	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CS032_RS20350	COG0318	PFAM AMP-dependent synthetase and ligase
CS032_RS20355	COG3065	identical protein binding
CS032_RS20360	COG1214	PFAM Peptidase M22, glycoprotease
CS032_RS20365	COG1199	ATP-dependent helicase activity
CS032_RS20370	COG0251	oxidation-reduction process
CS032_RS20385	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CS032_RS20395	COG1760	l-serine dehydratase
CS032_RS20400	COG2200	EAL domain
CS032_RS20405	COG1253	flavin adenine dinucleotide binding
CS032_RS20420	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CS032_RS20420	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CS032_RS20425	COG3715	PTS system
CS032_RS20430	COG3716	PTS system mannose fructose sorbose family IID component
CS032_RS20450	COG2226	methyltransferase
CS032_RS20485	COG1414	Transcriptional regulator
CS032_RS20490	COG2814	Major facilitator Superfamily
CS032_RS20500	COG0793	Belongs to the peptidase S41A family
CS032_RS20510	COG1956	GAF domain-containing protein
CS032_RS20515	COG2995	paraquat-inducible protein a
CS032_RS20520	COG3008	intermembrane lipid transfer
CS032_RS20540	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CS032_RS20550	COG1276	copper resistance
CS032_RS20555	COG2372	response to copper ion
CS032_RS20565	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CS032_RS20570	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CS032_RS20575	COG1770	oligopeptidase
CS032_RS20580	COG2979	Protein of unknown function (DUF533)
CS032_RS20590	COG3141	response to X-ray
CS032_RS20600	COG0800	Aldolase
CS032_RS20605	COG0129	dihydroxy-acid dehydratase activity
CS032_RS20610	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CS032_RS20615	COG1737	Transcriptional regulator
CS032_RS20620	COG0469	pyruvate kinase activity
CS032_RS20625	COG1560	Kdo2-lipid A biosynthetic process
CS032_RS20630	COG0739	heme binding
CS032_RS20635	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CS032_RS20645	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CS032_RS20675	COG0217	transcriptional regulatory protein
CS032_RS20680	COG0494	nUDIX hydrolase
CS032_RS20690	COG1335	isochorismatase
CS032_RS20715	COG3778	Protein conserved in bacteria
CS032_RS20720	COG3299	homolog of phage Mu protein gp47
CS032_RS20735	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CS032_RS20760	COG4386	tail sheath protein
CS032_RS20800	COG4695	Portal protein
CS032_RS20885	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CS032_RS20890	COG1403	HNH endonuclease
CS032_RS20900	COG0305	Participates in initiation and elongation during chromosome replication
CS032_RS20905	COG1484	DNA-dependent DNA replication
CS032_RS20945	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CS032_RS21015	COG0582	viral genome integration into host DNA
CS032_RS21020	COG1801	Protein of unknown function DUF72
CS032_RS21025	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CS032_RS21040	COG0243	molybdopterin cofactor binding
CS032_RS21045	COG3005	denitrification pathway
CS032_RS21055	COG3102	Protein conserved in bacteria
CS032_RS21070	COG3755	Protein conserved in bacteria
CS032_RS21080	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CS032_RS21085	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CS032_RS21090	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CS032_RS21095	COG0745	RESPONSE REGULATOR receiver
CS032_RS21105	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CS032_RS21110	COG0840	transmembrane signaling receptor activity
CS032_RS21115	COG0840	transmembrane signaling receptor activity
CS032_RS21120	COG0835	chemotaxis
CS032_RS21125	COG0643	Histidine kinase
CS032_RS21125	COG2198	Histidine kinase
CS032_RS21130	COG1360	Flagellar Motor Protein
CS032_RS21135	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CS032_RS21150	COG0589	response to stress
CS032_RS21160	COG1877	trehalose-phosphatase activity
CS032_RS21165	COG1172	Belongs to the binding-protein-dependent transport system permease family
CS032_RS21170	COG1129	ABC transporter
CS032_RS21175	COG1879	ABC-type sugar transport system periplasmic component
CS032_RS21185	COG1528	Iron-storage protein
CS032_RS21205	COG1528	Iron-storage protein
CS032_RS21215	COG0814	amino acid
CS032_RS21220	COG3318	Belongs to the UPF0149 family
CS032_RS21220	COG3012	SEC-C Motif Domain Protein
CS032_RS21235	COG3436	PFAM IS66 Orf2 family protein
CS032_RS21240	COG4372	Transposase
CS032_RS21280	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CS032_RS21290	COG3318	Belongs to the UPF0149 family
CS032_RS21290	COG3012	SEC-C Motif Domain Protein
CS032_RS21405	COG2197	response regulator
CS032_RS21420	COG2197	response regulator
CS032_RS21425	COG1126	abc transporter atp-binding protein
CS032_RS21430	COG0765	amino acid transport
CS032_RS21440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS032_RS21450	COG1191	sigma factor activity
CS032_RS21465	COG1516	flagellar protein fliS
CS032_RS21475	COG0366	Alpha amylase catalytic
CS032_RS21490	COG2391	methyltransferase activity
CS032_RS21495	COG0425	Belongs to the sulfur carrier protein TusA family
CS032_RS21500	COG2135	peptidase activity
CS032_RS21505	COG0675	Transposase, IS605 OrfB family
CS032_RS21520	COG2207	Transcriptional regulator
CS032_RS21525	COG1881	PFAM PEBP family protein
CS032_RS21530	COG2076	Multidrug Resistance protein
CS032_RS21540	COG1766	The M ring may be actively involved in energy transduction
CS032_RS21545	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CS032_RS21550	COG1317	bacterial-type flagellum organization
CS032_RS21555	COG1157	protein secretion by the type III secretion system
CS032_RS21560	COG2882	bacterial-type flagellum organization
CS032_RS21565	COG3144	bacterial-type flagellum assembly
CS032_RS21570	COG1580	Controls the rotational direction of flagella during chemotaxis
CS032_RS21575	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CS032_RS21580	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CS032_RS21585	COG3190	flagellar
CS032_RS21590	COG1338	Plays a role in the flagellum-specific transport system
CS032_RS21595	COG1987	bacterial-type flagellum assembly
CS032_RS21600	COG1684	flagellar biosynthetic protein fliR
CS032_RS21605	COG2197	response regulator
CS032_RS21635	COG5475	Uncharacterized small protein (DUF2158)
CS032_RS21640	COG2354	Protein conserved in bacteria
CS032_RS21645	COG0697	spore germination
CS032_RS21650	COG3727	T/G mismatch-specific endonuclease activity
CS032_RS21655	COG0270	DNA (cytosine-5-)-methyltransferase activity
CS032_RS21685	COG2205	protein histidine kinase activity
CS032_RS21690	COG0745	RESPONSE REGULATOR receiver
CS032_RS21695	COG2351	hydroxyisourate hydrolase activity
CS032_RS21710	COG3443	Belongs to the bacterial solute-binding protein 9 family
CS032_RS21725	COG3038	cytochrome b561
CS032_RS21760	COG0477	Major facilitator Superfamily
CS032_RS21765	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CS032_RS21770	COG0217	transcriptional regulatory protein
CS032_RS21800	COG0534	Mate efflux family protein
CS032_RS21810	COG0583	DNA-binding transcription factor activity
CS032_RS21815	COG0583	DNA-binding transcription factor activity
CS032_RS21825	COG1376	ErfK ybiS ycfS ynhG family protein
CS032_RS21870	COG2003	Belongs to the UPF0758 family
CS032_RS21910	COG1289	transmembrane transporter activity
CS032_RS21920	COG1686	Belongs to the peptidase S11 family
CS032_RS21925	COG2925	Exonuclease
CS032_RS21930	COG0425	Belongs to the sulfur carrier protein TusA family
CS032_RS21935	COG2391	methyltransferase activity
CS032_RS21940	COG0531	amino acid
CS032_RS21950	COG0583	DNA-binding transcription factor activity
CS032_RS21955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CS032_RS21960	COG4115	mRNA cleavage
CS032_RS21965	COG2161	toxin-antitoxin pair type II binding
CS032_RS21995	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CS032_RS21995	COG0131	Imidazoleglycerol-phosphate dehydratase
CS032_RS22000	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CS032_RS22025	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CS032_RS22030	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CS032_RS22045	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CS032_RS22060	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CS032_RS22080	COG0110	maltose O-acetyltransferase activity
CS032_RS22090	COG0438	transferase activity, transferring glycosyl groups
CS032_RS22110	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CS032_RS22115	COG1091	dTDP-4-dehydrorhamnose reductase activity
CS032_RS22120	COG1088	dTDP-glucose 4,6-dehydratase activity
CS032_RS22130	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CS032_RS22140	COG0438	transferase activity, transferring glycosyl groups
CS032_RS22145	COG2327	Polysaccharide pyruvyl transferase
CS032_RS22150	COG2244	polysaccharide biosynthetic process
CS032_RS22155	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CS032_RS22160	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CS032_RS22165	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CS032_RS22165	COG0662	Cupin 2, conserved barrel domain protein
CS032_RS22170	COG0297	glycogen (starch) synthase activity
CS032_RS22175	COG1051	belongs to the nudix hydrolase family
CS032_RS22180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CS032_RS22185	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CS032_RS22190	COG0110	maltose O-acetyltransferase activity
CS032_RS22195	COG1216	Glycosyl transferase, family 2
CS032_RS22205	COG0438	transferase activity, transferring glycosyl groups
CS032_RS22210	COG1045	serine acetyltransferase
CS032_RS22215	COG0463	Glycosyl transferase, family 2
CS032_RS22220	COG0489	protein tyrosine kinase activity
CS032_RS22220	COG3206	protein involved in exopolysaccharide biosynthesis
CS032_RS22225	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CS032_RS22230	COG1596	polysaccharide export
CS032_RS22235	COG1253	flavin adenine dinucleotide binding
CS032_RS22240	COG2982	Protein involved in outer membrane biogenesis
CS032_RS22250	COG0572	uridine kinase
CS032_RS22260	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CS032_RS22265	COG0443	Heat shock 70 kDa protein
CS032_RS22270	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
CS032_RS22275	COG3779	Protein conserved in bacteria
CS032_RS22280	COG0631	protein serine/threonine phosphatase activity
CS032_RS22320	COG2205	protein histidine kinase activity
CS032_RS22325	COG0745	RESPONSE REGULATOR receiver
CS032_RS22335	COG0826	peptidase U32
CS032_RS22390	COG5301	cellulose 1,4-beta-cellobiosidase activity
CS032_RS22390	COG5301	cellulose 1,4-beta-cellobiosidase activity
CS032_RS22480	COG4695	Portal protein
CS032_RS22535	COG4974	Belongs to the 'phage' integrase family
CS032_RS22560	COG1063	alcohol dehydrogenase
CS032_RS22565	COG3775	system Galactitol-specific IIC component
CS032_RS22570	COG3414	Phosphotransferase system galactitol-specific IIB component
CS032_RS22575	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CS032_RS22590	COG1830	Aldolase
CS032_RS22595	COG2211	Major facilitator Superfamily
CS032_RS22600	COG1397	ADP-ribosylglycohydrolase
CS032_RS22605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CS032_RS22610	COG2188	Transcriptional regulator
CS032_RS22615	COG3757	hydrolase, family 25
CS032_RS22620	COG0351	phosphomethylpyrimidine kinase
CS032_RS22640	COG5455	response to cobalt ion
CS032_RS22645	COG3539	Fimbrial protein
CS032_RS22650	COG3188	usher protein
CS032_RS22660	COG3539	Fimbrial protein
CS032_RS22675	COG0489	protein tyrosine kinase activity
CS032_RS22700	COG3831	ATPase activity
CS032_RS22710	COG0714	Associated with various cellular activities
CS032_RS22715	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CS032_RS22720	COG3552	Protein containing von Willebrand factor type A (VWA) domain
CS032_RS22725	COG4715	Zinc finger, swim domain protein
CS032_RS22730	COG4808	Protein conserved in bacteria
CS032_RS22735	COG4807	Protein conserved in bacteria
CS032_RS22740	COG3279	Response regulator of the LytR AlgR family
CS032_RS22745	COG3275	phosphorelay sensor kinase activity
CS032_RS22750	COG0789	Transcriptional regulator
CS032_RS22760	COG1174	glycine betaine transport
CS032_RS22765	COG1125	glycine betaine transport
CS032_RS22770	COG1174	glycine betaine transport
CS032_RS22775	COG1732	Glycine betaine
CS032_RS22780	COG1472	Belongs to the glycosyl hydrolase 3 family
CS032_RS22785	COG0277	FAD linked oxidase domain protein
CS032_RS22790	COG1686	Belongs to the peptidase S11 family
CS032_RS22800	COG0586	Pfam SNARE associated Golgi protein
CS032_RS22805	COG1028	Short-chain dehydrogenase reductase Sdr
CS032_RS22830	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CS032_RS22840	COG1346	cytolysis
CS032_RS22850	COG2949	membrane
CS032_RS22860	COG0493	'glutamate synthase
CS032_RS22865	COG0167	dihydroorotate dehydrogenase activity
CS032_RS22865	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CS032_RS22870	COG4211	Belongs to the binding-protein-dependent transport system permease family
CS032_RS22875	COG1129	ABC transporter
CS032_RS22880	COG1879	ABC-type sugar transport system periplasmic component
CS032_RS22885	COG1609	Transcriptional regulator
CS032_RS22895	COG2311	Membrane
CS032_RS22920	COG4771	TonB-dependent receptor
CS032_RS22930	COG0833	amino acid
CS032_RS22940	COG0583	DNA-binding transcription factor activity
CS032_RS22945	COG2855	membrane
CS032_RS22955	COG1522	sequence-specific DNA binding
CS032_RS22955	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CS032_RS22960	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CS032_RS22970	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CS032_RS22975	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CS032_RS22980	COG2313	pseudouridylate synthase activity
CS032_RS22985	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CS032_RS22990	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CS032_RS22990	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CS032_RS22990	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CS032_RS22995	COG1105	Belongs to the carbohydrate kinase PfkB family
CS032_RS23000	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CS032_RS23000	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CS032_RS23005	COG2814	Major facilitator Superfamily
CS032_RS23020	COG0246	Mannitol dehydrogenase
CS032_RS23025	COG0523	cobalamin synthesis protein
CS032_RS23030	COG0671	phosphoesterase, PA-phosphatase related
CS032_RS23035	COG0791	NLP P60 protein
CS032_RS23040	COG2200	EAL domain
CS032_RS23045	COG4166	transmembrane transport
CS032_RS23050	COG4174	ABC transporter (Permease)
CS032_RS23055	COG4239	(ABC) transporter, permease
CS032_RS23060	COG4172	Belongs to the ABC transporter superfamily
CS032_RS23075	COG2814	Major facilitator Superfamily
CS032_RS23080	COG1187	pseudouridine synthase activity
CS032_RS23090	COG1061	Type III restriction enzyme res subunit
CS032_RS23110	COG3083	sulfuric ester hydrolase activity
CS032_RS23135	COG2197	response regulator
CS032_RS23140	COG4235	cytochrome complex assembly
CS032_RS23140	COG3088	subunit of a heme lyase
CS032_RS23145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CS032_RS23150	COG1138	Cytochrome C-type biogenesis protein
CS032_RS23160	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CS032_RS23165	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CS032_RS23170	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CS032_RS23175	COG4133	protoheme IX ABC transporter activity
CS032_RS23180	COG3005	denitrification pathway
CS032_RS23185	COG3043	anaerobic respiration
CS032_RS23190	COG0348	domain, Protein
CS032_RS23195	COG0437	4 iron, 4 sulfur cluster binding
CS032_RS23205	COG3062	negative regulation of establishment of protein localization
CS032_RS23210	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CS032_RS23210	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
CS032_RS23225	COG4615	Cyclic peptide transporter
CS032_RS23230	COG3145	DNA-N1-methyladenine dioxygenase activity
CS032_RS23235	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CS032_RS23235	COG2169	Transcriptional regulator
CS032_RS23240	COG1477	protein flavinylation
CS032_RS23245	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CS032_RS23260	COG2198	Histidine kinase
CS032_RS23260	COG0642	Histidine kinase
CS032_RS23265	COG2197	response regulator
CS032_RS23270	COG2205	protein histidine kinase activity
CS032_RS23270	COG0784	Response regulator, receiver
CS032_RS23275	COG3852	Histidine kinase
CS032_RS23280	COG2204	response regulator
CS032_RS23285	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CS032_RS23290	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CS032_RS23295	COG2031	fatty acid transporter
CS032_RS23300	COG0183	Belongs to the thiolase family
CS032_RS23305	COG4676	Protein conserved in bacteria
CS032_RS23310	COG5445	Predicted secreted protein (DUF2300)
CS032_RS23320	COG3234	Protein of unknown function (DUF1175)
CS032_RS23325	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
CS032_RS23330	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CS032_RS23340	COG3468	outer membrane autotransporter barrel domain protein
CS032_RS23350	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CS032_RS23355	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CS032_RS23360	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CS032_RS23365	COG3642	lipopolysaccharide core region biosynthetic process
CS032_RS23370	COG0583	DNA-binding transcription factor activity
CS032_RS23375	COG0584	glycerophosphoryl diester phosphodiesterase
CS032_RS23380	COG2271	Major facilitator Superfamily
CS032_RS23385	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CS032_RS23395	COG0247	lactate metabolic process
CS032_RS23400	COG5464	transposase or invertase
CS032_RS23415	COG2271	Major facilitator Superfamily
CS032_RS23425	COG1414	Transcriptional regulator
CS032_RS23490	COG0318	PFAM AMP-dependent synthetase and ligase
CS032_RS23500	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CS032_RS23515	COG1169	isochorismate synthase
CS032_RS23520	COG4575	ribosome binding
CS032_RS23525	COG2153	protein acetylation
CS032_RS23535	COG5160	protein modification by small protein removal
CS032_RS23540	COG2304	oxidoreductase activity
CS032_RS23545	COG2234	aminopeptidase activity
CS032_RS23565	COG0457	Tetratricopeptide repeat
CS032_RS23575	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CS032_RS23580	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CS032_RS23590	COG0839	Belongs to the complex I subunit 6 family
CS032_RS23605	COG1034	ATP synthesis coupled electron transport
CS032_RS23610	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CS032_RS23615	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CS032_RS23635	COG0583	DNA-binding transcription factor activity
CS032_RS23645	COG0436	Aminotransferase
CS032_RS23655	COG0490	domain, Protein
CS032_RS23655	COG0471	metal ion transport
CS032_RS23660	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CS032_RS23675	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CS032_RS23680	COG0857	belongs to the CobB CobQ family
CS032_RS23680	COG0280	phosphate acetyltransferase
CS032_RS23685	COG1288	antiporter activity
CS032_RS23690	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CS032_RS23695	COG0622	Phosphoesterase
CS032_RS23700	COG0625	glutathione transferase activity
CS032_RS23705	COG0625	glutathione transferase activity
CS032_RS23710	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CS032_RS23715	COG1090	epimerase
CS032_RS23720	COG5464	transposase or invertase
CS032_RS23725	COG4598	ABC transporter
CS032_RS23730	COG4160	amino acid transport
CS032_RS23735	COG4215	(ABC) transporter
CS032_RS23745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS032_RS23750	COG0163	prenyltransferase activity
CS032_RS23755	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CS032_RS23760	COG1286	toxin biosynthetic process
CS032_RS23765	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CS032_RS23770	COG0285	dihydrofolate synthase activity
CS032_RS23780	COG0586	Pfam SNARE associated Golgi protein
CS032_RS23790	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CS032_RS23805	COG2814	Major facilitator Superfamily
CS032_RS23815	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CS032_RS23830	COG3101	peptidyl-lysine hydroxylation
CS032_RS23835	COG0730	response to heat
CS032_RS23850	COG2890	protein-(glutamine-N5) methyltransferase activity
CS032_RS23865	COG3539	Fimbrial protein
CS032_RS23870	COG3539	Fimbrial protein
CS032_RS23875	COG3539	Fimbrial protein
CS032_RS23880	COG3121	Chaperone
CS032_RS23885	COG3188	usher protein
CS032_RS23890	COG3539	Fimbrial protein
CS032_RS23895	COG2062	phosphohistidine phosphatase, SixA
CS032_RS23910	COG3691	Protein conserved in bacteria
CS032_RS23920	COG2067	long-chain fatty acid transport protein
CS032_RS23945	COG2853	Lipoprotein
CS032_RS23955	COG2116	formate transmembrane transporter activity
CS032_RS23965	COG0582	viral genome integration into host DNA
CS032_RS24085	COG1783	phage Terminase large subunit
CS032_RS24185	COG0305	Participates in initiation and elongation during chromosome replication
CS032_RS24280	COG0583	DNA-binding transcription factor activity
CS032_RS24285	COG2610	gluconate transmembrane transporter activity
CS032_RS24295	COG0477	Major facilitator Superfamily
CS032_RS24300	COG1566	PFAM secretion protein HlyD family protein
CS032_RS24305	COG2197	response regulator
CS032_RS24315	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS032_RS24320	COG0679	Auxin Efflux Carrier
CS032_RS24325	COG0028	Belongs to the TPP enzyme family
CS032_RS24350	COG1560	Kdo2-lipid A biosynthetic process
CS032_RS24360	COG0436	Aminotransferase
CS032_RS24365	COG3275	phosphorelay sensor kinase activity
CS032_RS24370	COG3279	Response regulator of the LytR AlgR family
CS032_RS24375	COG2207	Transcriptional regulator
CS032_RS24380	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CS032_RS24380	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CS032_RS24380	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CS032_RS24385	COG1363	Peptidase, m42
CS032_RS24390	COG0006	proline dipeptidase activity
CS032_RS24395	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CS032_RS24400	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CS032_RS24425	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CS032_RS24440	COG2200	EAL domain
CS032_RS24440	COG2199	diguanylate cyclase activity
CS032_RS24455	COG3415	Transposase
CS032_RS24460	COG3415	Transposase
CS032_RS24495	COG0583	DNA-binding transcription factor activity
CS032_RS24505	COG2211	Major facilitator Superfamily
CS032_RS24510	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CS032_RS24520	COG0583	DNA-binding transcription factor activity
CS032_RS24525	COG0385	Bile acid
CS032_RS24530	COG3530	Putative quorum-sensing-regulated virulence factor
CS032_RS24550	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CS032_RS24555	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CS032_RS24560	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CS032_RS24565	COG2190	(PTS) system
CS032_RS24580	COG3831	ATPase activity
CS032_RS24580	COG4884	unkown
CS032_RS24585	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CS032_RS24590	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CS032_RS24595	COG4208	sulfate ABC transporter
CS032_RS24600	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CS032_RS24605	COG4150	thiosulfate binding
CS032_RS24615	COG1028	Short-chain dehydrogenase reductase Sdr
CS032_RS24630	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CS032_RS24630	COG1263	PTS System
CS032_RS24635	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CS032_RS24640	COG2837	iron assimilation
CS032_RS24655	COG0456	acetyltransferase
CS032_RS24660	COG0860	N-Acetylmuramoyl-L-alanine amidase
CS032_RS24670	COG2207	Transcriptional regulator
CS032_RS24675	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CS032_RS24680	COG4816	utilization protein
CS032_RS24690	COG4303	Ethanolamine ammonia lyase large subunit
CS032_RS24695	COG0582	viral genome integration into host DNA
CS032_RS24740	COG0076	glutamate decarboxylase activity
CS032_RS24745	COG0076	glutamate decarboxylase activity
CS032_RS24750	COG0531	amino acid
CS032_RS24755	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CS032_RS24770	COG3192	ethanolamine utilization protein
CS032_RS24775	COG1454	alcohol dehydrogenase
CS032_RS24780	COG4820	ethanolamine utilization protein (EutJ)
CS032_RS24785	COG1012	belongs to the aldehyde dehydrogenase family
CS032_RS24790	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
CS032_RS24795	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CS032_RS24800	COG0280	phosphate acetyltransferase
CS032_RS24805	COG4812	Cobalamin adenosyltransferase
CS032_RS24810	COG4766	ethanolamine catabolic process
CS032_RS24815	COG4917	ethanolamine utilization protein
CS032_RS24820	COG4810	utilization protein
CS032_RS24825	COG0281	malic enzyme
CS032_RS24825	COG0280	phosphate acetyltransferase
CS032_RS24830	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CS032_RS24835	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CS032_RS24840	COG5342	invasion associated locus B
CS032_RS24850	COG0493	'glutamate synthase
CS032_RS24850	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CS032_RS24855	COG3850	Histidine kinase
CS032_RS24860	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CS032_RS24865	COG1393	Belongs to the ArsC family
CS032_RS24880	COG0400	carboxylic ester hydrolase activity
CS032_RS24885	COG1444	tRNA N-acetyltransferase activity
CS032_RS24890	COG2321	neutral zinc metallopeptidase
CS032_RS24900	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CS032_RS24910	COG2716	regulation of RNA biosynthetic process
CS032_RS24915	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CS032_RS24920	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CS032_RS24930	COG0650	Formate hydrogenlyase subunit 4
CS032_RS24935	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CS032_RS24940	COG4237	Hydrogenase 4 membrane
CS032_RS24950	COG3261	NADH dehydrogenase
CS032_RS24950	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CS032_RS24955	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CS032_RS24960	COG3260	NADH ubiquinone oxidoreductase 20
CS032_RS24970	COG3604	Transcriptional regulator
CS032_RS24975	COG2116	formate transmembrane transporter activity
CS032_RS24985	COG0628	permease
CS032_RS24990	COG4783	chaperone-mediated protein folding
CS032_RS24995	COG1393	Belongs to the ArsC family
CS032_RS25005	COG2233	PERMEase
CS032_RS25025	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CS032_RS25030	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CS032_RS25035	COG0248	Ppx GppA phosphatase
CS032_RS25055	COG2200	EAL domain
CS032_RS25100	COG0517	IMP dehydrogenase activity
CS032_RS25100	COG0516	GMP reductase activity
CS032_RS25110	COG1645	bacterial-type flagellum-dependent swarming motility
CS032_RS25125	COG2976	Protein conserved in bacteria
CS032_RS25165	COG2373	Large extracellular alpha-helical protein
CS032_RS25185	COG2975	iron-sulfur cluster assembly
CS032_RS25190	COG0633	Ferredoxin
CS032_RS25210	COG0822	iron-sulfur transferase activity
CS032_RS25230	COG0483	inositol monophosphate 1-phosphatase activity
CS032_RS25235	COG1073	alpha beta
CS032_RS25240	COG3711	transcriptional antiterminator
CS032_RS25245	COG2814	Major facilitator Superfamily
CS032_RS25250	COG0583	DNA-binding transcription factor activity
CS032_RS25255	COG4638	Rieske (2fe-2S)
CS032_RS25280	COG2259	Doxx family
CS032_RS25285	COG2017	converts alpha-aldose to the beta-anomer
CS032_RS25290	COG1063	alcohol dehydrogenase
CS032_RS25295	COG1172	Belongs to the binding-protein-dependent transport system permease family
CS032_RS25300	COG1129	ABC transporter
CS032_RS25305	COG1879	ABC-type sugar transport system periplasmic component
CS032_RS25310	COG0457	Tetratricopeptide repeat
CS032_RS25315	COG1940	carbohydrate kinase activity
CS032_RS25325	COG1017	nitric oxide dioxygenase activity
CS032_RS25325	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CS032_RS25330	COG0347	Belongs to the P(II) protein family
CS032_RS25335	COG2204	response regulator
CS032_RS25340	COG3170	Tfp pilus assembly protein FimV
CS032_RS25345	COG2205	protein histidine kinase activity
CS032_RS25370	COG0560	Phosphoserine phosphatase
CS032_RS25375	COG1737	Transcriptional regulator
CS032_RS25380	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CS032_RS25405	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CS032_RS25430	COG0681	Belongs to the peptidase S26 family
CS032_RS25440	COG3086	response to oxidative stress
CS032_RS25445	COG3026	antisigma factor binding
CS032_RS25450	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
CS032_RS25455	COG1595	DNA-templated transcription, initiation
CS032_RS25470	COG0513	Belongs to the DEAD box helicase family
CS032_RS25475	COG0583	DNA-binding transcription factor activity
CS032_RS25495	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CS032_RS25505	COG3118	belongs to the thioredoxin family
CS032_RS25510	COG3148	PFAM DTW domain containing protein
CS032_RS25515	COG1042	CoA-binding domain protein
CS032_RS25515	COG0045	succinate-CoA ligase (ADP-forming) activity
CS032_RS25515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CS032_RS25520	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CS032_RS25525	COG5544	Lipoprotein
CS032_RS25530	COG0477	Major facilitator Superfamily
CS032_RS25560	COG0542	response to heat
CS032_RS25565	COG1496	oxidoreductase activity
CS032_RS25570	COG0564	pseudouridine synthase activity
CS032_RS25575	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CS032_RS25585	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CS032_RS25590	COG0077	Prephenate dehydratase
CS032_RS25590	COG1605	Chorismate mutase
CS032_RS25595	COG1605	Chorismate mutase
CS032_RS25595	COG0287	Prephenate dehydrogenase
CS032_RS25600	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CS032_RS25615	COG2199	diguanylate cyclase activity
CS032_RS25620	COG2885	chlorophyll binding
CS032_RS25645	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CS032_RS25650	COG4137	Cytochrome C assembly protein
CS032_RS25655	COG4536	flavin adenine dinucleotide binding
CS032_RS25675	COG0497	DNA recombination
CS032_RS25680	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CS032_RS25690	COG2867	negative regulation of translational initiation
CS032_RS25705	COG3468	outer membrane autotransporter barrel domain protein
CS032_RS25750	COG0579	oxidoreductase
CS032_RS25755	COG1012	belongs to the aldehyde dehydrogenase family
CS032_RS25760	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CS032_RS25765	COG1113	amino acid transport
CS032_RS25770	COG1802	Transcriptional regulator
CS032_RS25775	COG1652	LysM domain
CS032_RS25780	COG0401	homolog of Blt101
CS032_RS25785	COG0640	Transcriptional regulator
CS032_RS25790	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CS032_RS25795	COG2916	Histone family protein nucleoid-structuring protein H-NS
CS032_RS25810	COG4575	ribosome binding
CS032_RS25815	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CS032_RS25825	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CS032_RS25830	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CS032_RS25835	COG4175	Glycine betaine
CS032_RS25840	COG4176	ABC-type proline glycine betaine transport system permease component
CS032_RS25845	COG2113	Glycine betaine
CS032_RS25850	COG2814	Major facilitator Superfamily
CS032_RS25855	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CS032_RS25865	COG1846	Transcriptional regulator
CS032_RS25870	COG1566	PFAM secretion protein HlyD family protein
CS032_RS25875	COG2814	Major facilitator Superfamily
CS032_RS25890	COG1238	metal cluster binding
CS032_RS25895	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CS032_RS25925	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CS032_RS25945	COG1546	Belongs to the CinA family
CS032_RS25955	COG3730	PTS system glucitol sorbitol-specific
CS032_RS25960	COG3732	PTS system glucitol sorbitol-specific
CS032_RS25965	COG3731	PTS system glucitol sorbitol-specific IIA component
CS032_RS25970	COG1028	Short-chain dehydrogenase reductase Sdr
CS032_RS25975	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
CS032_RS25980	COG1349	DNA-binding transcription factor activity
CS032_RS25985	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CS032_RS25985	COG0517	IMP dehydrogenase activity
CS032_RS26005	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CS032_RS26010	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CS032_RS26015	COG1609	Transcriptional regulator
CS032_RS26020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CS032_RS26020	COG1263	PTS System
CS032_RS26025	COG2723	6-phospho-beta-galactosidase activity
CS032_RS26030	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CS032_RS26040	COG3260	NADH ubiquinone oxidoreductase 20
CS032_RS26045	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CS032_RS26050	COG3261	NADH dehydrogenase
CS032_RS26050	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CS032_RS26055	COG0650	Formate hydrogenlyase subunit 4
CS032_RS26060	COG0651	ATP synthesis coupled electron transport
CS032_RS26065	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CS032_RS26075	COG0375	protein maturation
CS032_RS26080	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CS032_RS26085	COG0298	carbon dioxide binding
CS032_RS26090	COG0409	Hydrogenase expression formation protein
CS032_RS26095	COG0309	Hydrogenase expression formation protein (HypE)
CS032_RS26100	COG3604	Transcriptional regulator
CS032_RS26120	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CS032_RS26130	COG0235	Class ii aldolase
CS032_RS26135	COG3622	Belongs to the hyi family
CS032_RS26140	COG2610	gluconate transmembrane transporter activity
CS032_RS26145	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CS032_RS26150	COG4942	peptidase
CS032_RS26150	COG1388	LysM domain
CS032_RS26205	COG2234	aminopeptidase activity
CS032_RS26210	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CS032_RS26215	COG1518	maintenance of DNA repeat elements
CS032_RS26230	COG1857	crispr-associated protein
CS032_RS26245	COG1203	CRISPR-associated helicase, Cas3
CS032_RS26260	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CS032_RS26270	COG0720	synthase
CS032_RS26275	COG0644	oxidoreductase
CS032_RS26280	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CS032_RS26285	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CS032_RS26290	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CS032_RS26295	COG2086	electron transfer activity
CS032_RS26300	COG0477	Major facilitator Superfamily
CS032_RS26305	COG0277	FAD linked oxidase domain protein
CS032_RS26310	COG1028	Short-chain dehydrogenase reductase Sdr
CS032_RS26315	COG2223	nitrite transmembrane transporter activity
CS032_RS26320	COG1070	Carbohydrate kinase
CS032_RS26325	COG0602	queuosine metabolic process
CS032_RS26360	COG3956	TIGRFAM MazG family protein
CS032_RS26365	COG2337	Toxic component of a toxin-antitoxin (TA) module
CS032_RS26370	COG2336	PFAM SpoVT AbrB
CS032_RS26375	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CS032_RS26380	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CS032_RS26385	COG3850	Histidine kinase
CS032_RS26385	COG3437	response regulator, receiver
CS032_RS26385	COG4999	Histidine kinase
CS032_RS26385	COG2205	protein histidine kinase activity
CS032_RS26390	COG4948	Mandelate Racemase Muconate Lactonizing
CS032_RS26395	COG4948	Mandelate Racemase Muconate Lactonizing
CS032_RS26400	COG2271	Major facilitator Superfamily
CS032_RS26405	COG0716	FMN binding
CS032_RS26410	COG0564	pseudouridine synthase activity
CS032_RS26415	COG3098	single-species biofilm formation
CS032_RS26430	COG1611	Belongs to the LOG family
CS032_RS26435	COG0814	amino acid
CS032_RS26440	COG1760	l-serine dehydratase
CS032_RS26450	COG1454	alcohol dehydrogenase
CS032_RS26455	COG0235	Class ii aldolase
CS032_RS26460	COG0738	Major facilitator superfamily
CS032_RS26470	COG1070	Carbohydrate kinase
CS032_RS26480	COG1349	DNA-binding transcription factor activity
CS032_RS26490	COG2363	Small membrane protein
CS032_RS26495	COG0583	DNA-binding transcription factor activity
CS032_RS26505	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CS032_RS26510	COG2166	iron-sulfur cluster assembly
CS032_RS26515	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CS032_RS26520	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CS032_RS26545	COG0860	N-Acetylmuramoyl-L-alanine amidase
CS032_RS26555	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CS032_RS26555	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CS032_RS26560	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CS032_RS26570	COG1025	Belongs to the peptidase M16 family
CS032_RS26575	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CS032_RS26580	COG4967	type IV pilus modification protein PilV
CS032_RS26590	COG4795	General secretion pathway protein
CS032_RS26595	COG2165	general secretion pathway protein
CS032_RS26610	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
CS032_RS26625	COG0861	Integral membrane protein TerC family
CS032_RS26635	COG0667	Aldo Keto reductase
CS032_RS26650	COG1609	Transcriptional regulator
CS032_RS26660	COG0583	DNA-binding transcription factor activity
CS032_RS26665	COG1794	racemase activity, acting on amino acids and derivatives
CS032_RS26670	COG2814	Major facilitator Superfamily
CS032_RS26675	COG1028	Short-chain dehydrogenase reductase Sdr
CS032_RS26685	COG0183	Belongs to the thiolase family
CS032_RS26690	COG0814	amino acid
CS032_RS26695	COG2771	luxR family
CS032_RS26705	COG3387	PFAM Glycoside hydrolase 15-related
CS032_RS26710	COG3387	PFAM Glycoside hydrolase 15-related
CS032_RS26730	COG4942	peptidase
CS032_RS26740	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CS032_RS26745	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CS032_RS26750	COG2080	2 iron, 2 sulfur cluster binding
CS032_RS26755	COG3829	transcription factor binding
CS032_RS26760	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CS032_RS26765	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CS032_RS26770	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CS032_RS26780	COG0549	Belongs to the carbamate kinase family
CS032_RS26785	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CS032_RS26785	COG3608	succinylglutamate desuccinylase aspartoacylase
CS032_RS26795	COG2068	MobA-Related Protein
CS032_RS26800	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CS032_RS26800	COG0493	'glutamate synthase
CS032_RS26805	COG0402	S-adenosylhomocysteine deaminase activity
CS032_RS26815	COG2080	2 iron, 2 sulfur cluster binding
CS032_RS26815	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CS032_RS26820	COG2233	PERMEase
CS032_RS26825	COG0402	S-adenosylhomocysteine deaminase activity
CS032_RS26830	COG2252	PERMEase
CS032_RS26835	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CS032_RS26840	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CS032_RS26840	COG0493	'glutamate synthase
CS032_RS26850	COG2233	PERMEase
CS032_RS26865	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CS032_RS26875	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CS032_RS26880	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CS032_RS26885	COG4974	Belongs to the 'phage' integrase family
CS032_RS26890	COG0716	FMN binding
CS032_RS26900	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CS032_RS26910	COG1272	protein, Hemolysin III
CS032_RS26920	COG2723	6-phospho-beta-galactosidase activity
CS032_RS26940	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CS032_RS26945	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CS032_RS26950	COG0006	proline dipeptidase activity
CS032_RS26975	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CS032_RS26990	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CS032_RS27010	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CS032_RS27010	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CS032_RS27020	COG1024	Enoyl-CoA hydratase
CS032_RS27025	COG0427	acetyl-CoA hydrolase
CS032_RS27030	COG0583	DNA-binding transcription factor activity
CS032_RS27035	COG2968	Membrane
CS032_RS27040	COG1279	arginine transmembrane transporter activity
CS032_RS27045	COG0668	transmembrane transport
CS032_RS27055	COG0191	fructose-bisphosphate aldolase activity
CS032_RS27075	COG1072	(Pantothenic acid kinase))
CS032_RS27080	COG3722	fumarate hydratase activity
CS032_RS27085	COG1494	fructose-1,6-bisphosphatase
CS032_RS27090	COG1063	alcohol dehydrogenase
CS032_RS27095	COG2213	PTS system mannitol-specific
CS032_RS27100	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CS032_RS27105	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CS032_RS27110	COG0501	Belongs to the peptidase M48B family
CS032_RS27120	COG1166	arginine decarboxylase activity
CS032_RS27145	COG2814	Major facilitator Superfamily
CS032_RS27155	COG2356	endonuclease I
CS032_RS27160	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CS032_RS27165	COG0189	ligase activity
CS032_RS27180	COG2805	Type II/IV secretion system protein
CS032_RS27185	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CS032_RS27190	COG0762	integral membrane protein