locus-tag class description GSU80_RS00010 ENOG4105CFH Aspartokinase GSU80_RS00020 ENOG4105D98 threonine synthase GSU80_RS00025 ENOG41062C6 Protein of unknown function (DUF2502) GSU80_RS00030 ENOG4105D1Q UPF0246 protein GSU80_RS00035 ENOG4105BZG amino acid carrier protein GSU80_RS00045 ENOG4108RIR Molybdenum cofactor biosynthesis protein GSU80_RS00050 ENOG4106HK8 GPR1 FUN34 yaaH family protein GSU80_RS00055 ENOG4108QUJ UPF0174 protein YaaW GSU80_RS00075 ENOG4108SER Transposase GSU80_RS00080 ENOG4105WI6 cell killing protein encoded within cryptic prophage GSU80_RS00090 ENOG41063Z6 transcriptional regulator, lysR family GSU80_RS00125 ENOG410647N response to DNA damage stimulus GSU80_RS00130 ENOG4105DTN riboflavin biosynthesis protein ribF GSU80_RS00135 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) GSU80_RS00145 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase GSU80_RS00165 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain GSU80_RS00170 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain GSU80_RS00175 ENOG4108XNW Transcriptional activatory protein CaiF GSU80_RS00185 ENOG4106YT9 Enoyl-CoA hydratase GSU80_RS00190 ENOG4105CEY Amp-dependent synthetase and ligase GSU80_RS00220 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase GSU80_RS00225 ENOG4105IBM Could be part of an electron transfer system required for anaerobic carnitine reduction. Could be a 3Fe-4S cluster- containing protein GSU80_RS00230 ENOG4105C54 Major Facilitator superfamily GSU80_RS00245 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) GSU80_RS00270 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) GSU80_RS00275 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) GSU80_RS00280 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) GSU80_RS00285 ENOG4105D3G Pseudouridine synthase GSU80_RS00295 ENOG4105CQ2 DNA polymerase GSU80_RS00300 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase GSU80_RS00305 ENOG4105CAC Catalyzes the conversion of L-arabinose to L-ribulose (By similarity) GSU80_RS00320 ENOG41063TF transcriptional regulator (AraC GSU80_RS00325 ENOG4108KF1 Membrane GSU80_RS00330 ENOG4107T0D ABC, transporter GSU80_RS00335 ENOG4106SMU thiamine transporter membrane protein GSU80_RS00340 ENOG4105DP9 ABC transporter GSU80_RS00355 ENOG4105S8Q sugar efflux transporter GSU80_RS00370 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) GSU80_RS00385 ENOG41064T2 transcriptional regulator, lysR family GSU80_RS00390 ENOG4105C7K acetolactate synthase GSU80_RS00395 ENOG4108ZP8 Acetolactate synthase small subunit GSU80_RS00405 ENOG4107B7Y DNA-binding transcriptional regulator FruR GSU80_RS00420 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) GSU80_RS00425 ENOG4105CJN penicillin-binding protein GSU80_RS00430 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) GSU80_RS00435 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) GSU80_RS00445 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) GSU80_RS00450 ENOG4105CNI cell division protein FtsW GSU80_RS00465 ENOG4105CPF Cell wall formation (By similarity) GSU80_RS00470 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) GSU80_RS00475 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) GSU80_RS00480 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) GSU80_RS00500 ENOG4105M6F mutator MutT protein GSU80_RS00515 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) GSU80_RS00525 ENOG4105D7Q type ii secretion system GSU80_RS00530 ENOG4107QHF type ii secretion system protein e GSU80_RS00535 ENOG4108ZUW Major pilin subunit GSU80_RS00540 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase GSU80_RS00545 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase GSU80_RS00550 ENOG4106A72 regulatory protein AmpE GSU80_RS00555 ENOG4105C85 amino acid GSU80_RS00560 ENOG41073TP transcriptional regulator GSU80_RS00565 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) GSU80_RS00570 ENOG4107QSN dihydrolipoamide acetyltransferase GSU80_RS00575 ENOG4107QN2 dihydrolipoyl dehydrogenase GSU80_RS00580 ENOG4108NST exported protein GSU80_RS00585 ENOG4107QIJ Aconitate hydratase 2 GSU80_RS00605 ENOG4108ZRK uncharacterized protein yacC GSU80_RS00610 ENOG4105E3B Multicopper oxidase GSU80_RS00615 ENOG4105DZG Dehydrogenase GSU80_RS00620 ENOG4108UGV hypoxanthine phosphoribosyltransferase GSU80_RS00625 ENOG41077A9 carbonic anhydrase GSU80_RS00630 ENOG4105DA5 (ABC) transporter GSU80_RS00635 ENOG4105E3A (ABC) transporter GSU80_RS00640 ENOG4108YTN IIa component GSU80_RS00645 ENOG4107BJW polysaccharide deacetylase GSU80_RS00655 ENOG4108A32 Transposase GSU80_RS00660 ENOG4108IAA Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity) GSU80_RS00670 ENOG4105P0Q fimbrial-like protein YadC GSU80_RS00675 ENOG4105SN2 fimbrial-like adhesin protein GSU80_RS00680 ENOG4105SYG Fimbrial protein GSU80_RS00685 ENOG4108XEY fimbrial-like adhesin protein GSU80_RS00690 ENOG4105CW0 outer membrane usher protein GSU80_RS00695 ENOG4108VEV chaperone GSU80_RS00705 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase GSU80_RS00710 ENOG4105DJ0 Poly(A) Polymerase GSU80_RS00720 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters GSU80_RS00730 ENOG4107XID 2'-5' rna ligase GSU80_RS00735 ENOG4105CQ7 ATP-dependent helicase GSU80_RS00740 ENOG4105BZ4 penicillin-binding protein GSU80_RS00745 ENOG4105E0K tonB-dependent siderophore receptor GSU80_RS00750 ENOG4105E0A ABC, transporter GSU80_RS00755 ENOG4105J76 Periplasmic binding protein GSU80_RS00760 ENOG4105S6R Iron-hydroxamate transporter permease subunit GSU80_RS00785 ENOG4105EN6 Membrane GSU80_RS00790 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) GSU80_RS00805 ENOG4105C0H protease GSU80_RS00810 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR GSU80_RS00820 ENOG4105DIN metallophosphoesterase GSU80_RS00830 ENOG4105E1P Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity) GSU80_RS00835 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) GSU80_RS00860 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) GSU80_RS00865 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) GSU80_RS00870 ENOG4105KNE Phosphatidate cytidylyltransferase GSU80_RS00875 ENOG4105DZP Membrane-associated zinc metalloprotease GSU80_RS00885 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) GSU80_RS00890 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) GSU80_RS00910 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) GSU80_RS00915 ENOG4105C0B DNA polymerase III (alpha subunit) GSU80_RS00925 ENOG4105CXN decarboxylase GSU80_RS00930 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase GSU80_RS00935 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) GSU80_RS00940 ENOG4105M1T rho-binding antiterminator GSU80_RS00950 ENOG4108VWS Yaeq family GSU80_RS00955 ENOG4108YZN class I peptide chain release factor GSU80_RS00960 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion GSU80_RS00965 ENOG4108UY0 (LipO)protein GSU80_RS00975 ENOG4108R96 Methyltransferase, YaeB family GSU80_RS00980 ENOG4108R8X outer membrane lipoprotein GSU80_RS00985 ENOG4105D01 (LipO)protein GSU80_RS00990 ENOG4108UMI ABC transporter, permease GSU80_RS00995 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) GSU80_RS01000 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase GSU80_RS01035 ENOG4105CV8 reductase GSU80_RS01040 ENOG4105HEI LysR family (Transcriptional regulator GSU80_RS01050 ENOG4105F2W methyltransferase GSU80_RS01055 ENOG4105E9H Lytic Murein transglycosylase GSU80_RS01060 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) GSU80_RS01065 ENOG4105D1A Methyltransferase GSU80_RS01075 ENOG4107RZZ dna polymerase iii epsilon subunit GSU80_RS01085 ENOG410600K aminopeptidase GSU80_RS01100 ENOG410600T transposase GSU80_RS01110 ENOG4108WN0 inhibitor of vertebrate lysozyme GSU80_RS01115 ENOG4107QPN acyl-Coa dehydrogenase GSU80_RS01125 ENOG4105E7A Glutamine amidotransferase GSU80_RS01130 ENOG4105F7V ErfK ybiS ycfS ynhG family protein GSU80_RS01145 ENOG4108YS0 lipoprotein YafL GSU80_RS01150 ENOG4108UK5 Transposase GSU80_RS01165 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) GSU80_RS01170 ENOG4105UG9 Antitoxin of the YafO-YafN toxin-antitoxin system GSU80_RS01175 ENOG41065DM this blockage is overcome by subsequent expression of antitoxin YafN. Overexpression causes cleavage of a number of mRNAs in a ribosome-dependent fashion. YafO binding to the 50S ribosomal subunit in the translation complex induces mRNA cleavage 3' to the region protected by the ribosome GSU80_RS01180 ENOG4108HYG acetyltransferase GSU80_RS01190 ENOG4108S2Y peptide Chain Release factor GSU80_RS01195 ENOG4105CIN aminoacyl-histidine dipeptidase GSU80_RS01220 ENOG4105FCK Membrane GSU80_RS01245 ENOG4107XAN XdhC and CoxI family GSU80_RS01250 ENOG4105C7W Xanthine dehydrogenase GSU80_RS01255 ENOG4105DIP Molybdopterin dehydrogenase FAD-binding GSU80_RS01260 ENOG4107XKX isoquinoline 1-oxidoreductase, alpha subunit GSU80_RS01265 ENOG4105R3P Inner membrane protein yagU GSU80_RS01275 ENOG4105PI0 Ferredoxin GSU80_RS01280 ENOG4108UD7 cell wall organization GSU80_RS01285 ENOG4106PYX Receptor GSU80_RS01290 ENOG4108N3D putative enzyme GSU80_RS01305 ENOG4106JB4 Represses expression of the flagellar master operon flhDC, and consequently prevents flagellum biosynthesis and motility. Acts by binding to the regulatory region of the flhDC operon GSU80_RS01320 ENOG4105NRA 50s ribosomal protein l31 type b GSU80_RS01350 ENOG4108KBJ Inner membrane protein YkgB GSU80_RS01355 ENOG41066GK UPF0379 protein ykgI GSU80_RS01360 ENOG4107QN2 dihydrolipoyl dehydrogenase GSU80_RS01365 ENOG4108K01 transcriptional regulator GSU80_RS01370 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) GSU80_RS01375 ENOG4107QR9 Iron-sulfur cluster binding protein GSU80_RS01380 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) GSU80_RS01390 ENOG4105CZ6 Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity) GSU80_RS01400 ENOG4108MHR Repressor involved in choline regulation of the bet genes (By similarity) GSU80_RS01405 ENOG4105C94 Transporter GSU80_RS01415 ENOG4105BZU Histidine kinase GSU80_RS01420 ENOG4108NUU Transcriptional regulator GSU80_RS01425 ENOG4105SZ2 membrAne GSU80_RS01430 ENOG4107SNB ankyrin repeat protein YahD GSU80_RS01435 ENOG4105N16 Protein of unknown function (DUF2877) GSU80_RS01440 ENOG4107R1Q Membrane protein FdrA GSU80_RS01445 ENOG4107REC cytoplasmic protein GSU80_RS01455 ENOG4105C5B carbamate kinase GSU80_RS01460 ENOG4105DZC cytosine deaminase GSU80_RS01465 ENOG4105DQ4 alcohol dehydrogenase GSU80_RS01480 ENOG4105E82 cytochrome subunit of dehydrogenase GSU80_RS01485 ENOG4105TDT uncharacterized protein yahO GSU80_RS01490 ENOG4108JU7 Transcriptional regulator GSU80_RS01495 ENOG4105CR4 methylisocitrate lyase GSU80_RS01500 ENOG4105BZN citrate synthase GSU80_RS01505 ENOG4105DXD 2-methylcitrate dehydratase GSU80_RS01510 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) GSU80_RS01515 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin GSU80_RS01520 ENOG4105DZC cytosine deaminase GSU80_RS01525 ENOG4105DND Transcriptional regulator GSU80_RS01530 ENOG4107B2H carbonic anhydrase GSU80_RS01535 ENOG4108V7B Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity) GSU80_RS01540 ENOG4105DJ2 Major Facilitator Superfamily GSU80_RS01545 ENOG4108UW5 maltose o-acetyltransferase GSU80_RS01550 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) GSU80_RS01555 ENOG4105CNT hydrolase family 2 GSU80_RS01560 ENOG4105ETE Transcriptional regulator (LacI family GSU80_RS01565 ENOG4108K2P TRANSCRIPTIONal GSU80_RS01575 ENOG4105MI0 Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively (By similarity) GSU80_RS01585 ENOG4105IKQ hydratase GSU80_RS01600 ENOG4108SC4 )-transporter GSU80_RS01605 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme GSU80_RS01610 ENOG4105C4W S-formylglutathione hydrolase GSU80_RS01625 ENOG4105SRB Uncharacterized protein yaiO GSU80_RS01635 ENOG4106FTQ Taurine ABC transporter, periplasmic GSU80_RS01640 ENOG4108ETV ABC transporter GSU80_RS01645 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component GSU80_RS01650 ENOG4105E2B Taurine dioxygenase GSU80_RS01655 ENOG4105D52 delta-aminolevulinic acid dehydratase GSU80_RS01665 ENOG4108PNB DNA-binding transcriptional regulator GSU80_RS01670 ENOG4107R6D beta-lactam binding protein AmpH GSU80_RS01675 ENOG4108DQG in Escherichia coli SbmA is involved in uptake of microcin J25 GSU80_RS01680 ENOG4107QS8 (LipO)protein GSU80_RS01685 ENOG4105FR5 inner membrane protein YaiY GSU80_RS01690 ENOG4105UNH Membrane GSU80_RS01695 ENOG4105CPF Cell wall formation (By similarity) GSU80_RS01705 ENOG4105G6Z alkaline phosphatase GSU80_RS01710 ENOG4105VIF phosphate starvation-inducible protein GSU80_RS01715 ENOG4105BZU Histidine kinase GSU80_RS01720 ENOG4105II7 pyrroline-5-carboxylate reductase GSU80_RS01735 ENOG4105SS3 GSU80_RS01740 ENOG4105HBA AroM protein GSU80_RS01770 ENOG4105DKQ ROK family GSU80_RS01775 ENOG4105F27 Major Facilitator GSU80_RS01780 ENOG4105EYH Exonuclease GSU80_RS01785 ENOG4107RH8 nuclease SbcCD subunit D GSU80_RS01790 ENOG4105CK6 Two component transcriptional regulator (Winged helix family GSU80_RS01795 ENOG4105BZU Histidine kinase GSU80_RS01800 ENOG4105CWM branched-chain amino acid transport system II carrier protein GSU80_RS01805 ENOG4105C85 amino acid GSU80_RS01810 ENOG4107R28 alpha amylase, catalytic region GSU80_RS01830 ENOG4105VIE preprotein translocase, subunit YajC GSU80_RS01835 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) GSU80_RS01840 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) GSU80_RS01845 ENOG4105N1F Hnh endonuclease GSU80_RS01850 ENOG4105DRB nucleoside-specific channel-forming protein GSU80_RS01855 ENOG4108KIC (LipO)protein GSU80_RS01865 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) GSU80_RS01870 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) GSU80_RS01880 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) GSU80_RS01885 ENOG4108ZAI phosphatidylglycerophosphatase a GSU80_RS01890 ENOG4105CPC Aldo Keto reductase GSU80_RS01900 ENOG4105CTB Polyprenyl synthetase GSU80_RS01915 ENOG4107S0N DJ-1 family GSU80_RS01920 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) GSU80_RS01930 ENOG4107RDB Major Facilitator GSU80_RS01955 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) GSU80_RS01960 ENOG4105CCU oxidase (Subunit III) GSU80_RS01965 ENOG4105BZ9 Cytochrome C oxidase, subunit I GSU80_RS01970 ENOG4105E2S oxidase) subunit II GSU80_RS01975 ENOG4105EYM Major Facilitator superfamily GSU80_RS01980 ENOG4105IEY (LipO)protein GSU80_RS01985 ENOG4105M85 Bola protein GSU80_RS02005 ENOG4108SER Transposase GSU80_RS02010 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) GSU80_RS02015 ENOG4105K70 DNA-binding protein GSU80_RS02020 ENOG4105EIN peptidylprolyl cis-trans isomerase GSU80_RS02025 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein GSU80_RS02030 ENOG4108TGP Thioesterase superfamily protein GSU80_RS02040 ENOG4108NFA extracellular solute-binding protein GSU80_RS02050 ENOG4108XM1 transcriptional regulator AsnC family GSU80_RS02055 ENOG4105BZ1 (ABC) transporter GSU80_RS02060 ENOG4105BZ1 (ABC) transporter GSU80_RS02065 ENOG4108YZA Nitrogen regulatory protein pii GSU80_RS02070 ENOG4105BZU Histidine kinase GSU80_RS02075 ENOG4105C29 acyl-CoA thioesterase GSU80_RS02080 ENOG4108MNP Glycoprotein polysaccharide metabolism GSU80_RS02085 ENOG41080UX Methyltransferase GSU80_RS02095 ENOG4105KCV RNA signal recognition particle 4.5S RNA GSU80_RS02100 ENOG41066DG (EAL) domain protein GSU80_RS02105 ENOG4105GSJ Inner membrane protein ylaC GSU80_RS02110 ENOG4108UW5 maltose o-acetyltransferase GSU80_RS02115 ENOG4105KF5 hemolysin expression-modulating protein GSU80_RS02120 ENOG4108UKR Biofilm formation regulator YbaJ GSU80_RS02125 ENOG4105BZS acriflavin resistance protein GSU80_RS02130 ENOG4105C1P efflux transporter, rnd family, mfp subunit GSU80_RS02135 ENOG4108IG5 Transcriptional regulator GSU80_RS02140 ENOG4105EGS Mechanosensitive ion channel GSU80_RS02145 ENOG4106428 Protein of unknown function (DUF2496) GSU80_RS02150 ENOG4108URS primosomal replication protein n'' GSU80_RS02155 ENOG4105WD1 Membrane GSU80_RS02165 ENOG4107QMP dna polymerase iii subunits gamma and tau GSU80_RS02180 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) GSU80_RS02200 ENOG4107RE1 Inosine-guanosine kinase GSU80_RS02205 ENOG4105CKD glutathione-regulated potassium-efflux system protein GSU80_RS02210 ENOG4105EU0 Major facilitator Superfamily GSU80_RS02215 ENOG4105CGH 5'-nucleotidase GSU80_RS02220 ENOG4108Z66 YbaK ebsC protein GSU80_RS02225 ENOG4105MBR gumn family GSU80_RS02230 ENOG41081XE plasmid maintenance system antidote protein, xre family GSU80_RS02235 ENOG4105C59 p-type ATPase GSU80_RS02240 ENOG4105CSV Glutaminase GSU80_RS02245 ENOG4107RY6 amino acid GSU80_RS02250 ENOG4108Z6Z Transcriptional regulator GSU80_RS02255 ENOG4105G5H Membrane GSU80_RS02260 ENOG4107QX8 SPFH domain, Band 7 family protein GSU80_RS02265 ENOG41083J0 (ABC) transporter GSU80_RS02270 ENOG4105C4B ABC transporter, permease GSU80_RS02275 ENOG4107QR8 Thioredoxin GSU80_RS02280 ENOG4105E1F short-chain dehydrogenase reductase GSU80_RS02285 ENOG4108UJV acyl-CoA thioesterase i GSU80_RS02290 ENOG4108I0Y (ABC) transporter GSU80_RS02295 ENOG4105CV6 ABC transporter, permease GSU80_RS02300 ENOG4105CNA YD repeat protein GSU80_RS02320 ENOG4105CNA YD repeat protein GSU80_RS02335 ENOG4107653 Transcriptional regulator GSU80_RS02340 ENOG4108Z2U ureidoglycolate hydrolase GSU80_RS02345 ENOG4108N16 Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region GSU80_RS02350 ENOG41060W2 glyoxylate carboligase GSU80_RS02355 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) GSU80_RS02360 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase GSU80_RS02365 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease GSU80_RS02375 ENOG4105DTE Xanthine uracil vitamin C permease GSU80_RS02380 ENOG4105BZW Glycerate kinase GSU80_RS02385 ENOG4105S0E allantoin catabolism protein GSU80_RS02390 ENOG4105CE7 Amidase, hydantoinase carbamoylase family GSU80_RS02395 ENOG4105DG4 malate L-lactate dehydrogenase GSU80_RS02400 ENOG4107R1Q Membrane protein FdrA GSU80_RS02405 ENOG4107REC cytoplasmic protein GSU80_RS02410 ENOG4105G5A Protein of unknown function (DUF2877) GSU80_RS02415 ENOG4105C5B carbamate kinase GSU80_RS02420 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit GSU80_RS02425 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) GSU80_RS02435 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) GSU80_RS02445 ENOG4105S2T inner membrane protein YbcI GSU80_RS02450 ENOG4105WQ3 Rna-binding protein GSU80_RS02460 ENOG4108WDE Fimbrial protein GSU80_RS02465 ENOG4108AF8 Chaperone GSU80_RS02470 ENOG4105CW0 outer membrane usher protein GSU80_RS02475 ENOG4108M66 Involved in regulation of length and mediation of adhesion of SfmA fimbriae (but not necessary for the production of fimbriae). Seems to be mannose binding adhesin (By similarity) GSU80_RS02480 ENOG4108ZI2 Fimbrial protein GSU80_RS02485 ENOG4108Q9V regulatoR GSU80_RS02495 ENOG4108KU3 Integrase GSU80_RS02530 ENOG410814C multidrug resistance protein GSU80_RS02540 ENOG4107TII Recombinase GSU80_RS02545 ENOG4108V1U phospholipid-binding protein GSU80_RS02550 ENOG4108UQN AraC family transcriptional regulator GSU80_RS02560 ENOG4108V2F protein ybcN in lambdoid DLP12 prophage regi GSU80_RS02565 ENOG410757E Protein NinE homolog from lambdoid prophage DLP12 GSU80_RS02570 ENOG4105RWQ Protein of unknown function (DUF1364) GSU80_RS02585 ENOG4105HRS Antitermination protein GSU80_RS02605 ENOG4105QFS Lysis protein S homolog from lambdoid prophage GSU80_RS02610 ENOG4105KUS lysozyme GSU80_RS02620 ENOG4105QYK bacteriophage lambda Bor protein homolog GSU80_RS02625 ENOG4106YSC GSU80_RS02655 ENOG4105GR3 Histidine kinase GSU80_RS02660 ENOG4105CK6 Two component transcriptional regulator (Winged helix family GSU80_RS02665 ENOG4105ENJ RND efflux system, outer membrane lipoprotein GSU80_RS02670 ENOG410624V efflux system protein GSU80_RS02675 ENOG4105EP1 Efflux transporter rnd family, mfp subunit GSU80_RS02680 ENOG4108IJF Heavy metal efflux pump, CzcA GSU80_RS02685 ENOG4105C85 amino acid GSU80_RS02690 ENOG4105CUY Mechanosensitive ion channel GSU80_RS02695 ENOG4108RCM Nitroreductase GSU80_RS02700 ENOG4105MSB protein, conserved in bacteria GSU80_RS02705 ENOG4105WQ6 Membrane GSU80_RS02725 ENOG4105DQ6 Transposase GSU80_RS02730 ENOG4107635 Hok Gef family protein GSU80_RS02735 ENOG4108SER Transposase GSU80_RS02740 ENOG4108TSE Transferase GSU80_RS02745 ENOG4107RNH Outer membrane receptor FepA GSU80_RS02750 ENOG4105E93 esterase GSU80_RS02755 ENOG41085A6 mbth domain-containing protein GSU80_RS02760 ENOG4105C0W non-ribosomal peptide synthetase GSU80_RS02765 ENOG4108QY5 Ferric enterobactin transport protein GSU80_RS02770 ENOG4105E0A ABC, transporter GSU80_RS02775 ENOG4105TVJ transport system, permease GSU80_RS02780 ENOG4105DQ5 transport system permease protein GSU80_RS02790 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein GSU80_RS02795 ENOG4105E4F Isochorismate synthase GSU80_RS02800 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase GSU80_RS02805 ENOG4105WQI isochorismatase GSU80_RS02810 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase GSU80_RS02815 ENOG4108TZA Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules (By similarity) GSU80_RS02825 ENOG4105VCD cytoplasmic protein GSU80_RS02830 ENOG4107SCQ Iron-containing alcohol dehydrogenase GSU80_RS02835 ENOG4105CHM Aminotransferase GSU80_RS02840 ENOG4105GTN ParB Domain Protein Nuclease GSU80_RS02855 ENOG4108KHN disulfide isomerase, thiol-disulfide oxidase GSU80_RS02860 ENOG4105D3R alkyl hydroperoxide reductase GSU80_RS02865 ENOG4108JU3 Alkyl hydroperoxide reductase GSU80_RS02870 ENOG4108U51 Universal stress protein GSU80_RS02875 ENOG4105E2A Dehydrogenase GSU80_RS02880 ENOG4105NXH GreA GreB family elongation factor GSU80_RS02885 ENOG4105KTS ribonuclease GSU80_RS02890 ENOG4107QPK )-transporter GSU80_RS02905 ENOG4105CHY citrate lyase, alpha GSU80_RS02910 ENOG4105CI0 Citrate lyase GSU80_RS02920 ENOG4105DUA (citrate (pro-3S)-lyase ligase GSU80_RS02930 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism GSU80_RS02935 ENOG4106YYS transcriptional regulatory protein GSU80_RS02940 ENOG4105CEE C4-dicarboxylate transporter GSU80_RS02945 ENOG41079UR PagP is required both for biosynthesis of hepta-acylated lipid A species containing palmitate and for resistance to cationic antimicrobial peptides (CAMPs). It catalyzes the transfer of a palmitate chain (16 0) from the sn-1 position of a glycerophospholipid to the free hydroxyl group of the (R)-3- hydroxymyristate chain at position 2 of lipid A (endotoxin) (By similarity) GSU80_RS02950 ENOG4105VEQ Cold shock protein GSU80_RS02960 ENOG4107QPI nitrilase cyanide hydratase and apolipoprotein n-acyltransferase GSU80_RS02965 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) GSU80_RS02975 ENOG41064T2 transcriptional regulator, lysR family GSU80_RS02990 ENOG4105DZ1 carboxypeptidase GSU80_RS02995 ENOG4105K6T rare lipoprotein A GSU80_RS03000 ENOG4105CNI cell division protein FtsW GSU80_RS03005 ENOG4105CJN penicillin-binding protein GSU80_RS03015 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) GSU80_RS03020 ENOG4108TGR phosphatase GSU80_RS03030 ENOG4105DJF DNA polymerase III, delta' subunit GSU80_RS03045 ENOG4107PAI alpha helical protein GSU80_RS03055 ENOG41069CF Protein of unknown function (DUF1266) GSU80_RS03060 ENOG4105QFC Hsc56 co-chaperone of HscC GSU80_RS03065 ENOG4105F7F Chaperone GSU80_RS03085 ENOG4105CDA abc transporter atp-binding protein GSU80_RS03090 ENOG4105DRP amino acid AbC transporter GSU80_RS03095 ENOG4105EAD ABC transporter GSU80_RS03100 ENOG4107RP9 extracellular solute-binding protein, family 3 GSU80_RS03105 ENOG4107U91 Rhomboid family GSU80_RS03110 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) GSU80_RS03115 ENOG4108JU5 Magnesium and cobalt efflux protein GSU80_RS03125 ENOG4105C9A Phoh family GSU80_RS03135 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family GSU80_RS03175 ENOG4105CAQ asparagine synthetase GSU80_RS03180 ENOG4105D4U had-superfamily hydrolase, subfamily iia GSU80_RS03185 ENOG4105E2R ROK family GSU80_RS03190 ENOG4105CE4 GlcNAc 6-P deacetylase GSU80_RS03200 ENOG4105CI1 PTS System GSU80_RS03215 ENOG4105GX6 (LipO)protein GSU80_RS03220 ENOG41090R7 Ferric uptake GSU80_RS03230 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) GSU80_RS03235 ENOG4105NNH LexA regulated protein GSU80_RS03240 ENOG4105EV9 Alpha Beta Hydrolase GSU80_RS03245 ENOG4107CDU Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity) GSU80_RS03250 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 GSU80_RS03270 ENOG4105D5Q Arginine ornithine antiporter GSU80_RS03275 ENOG4105CXN decarboxylase GSU80_RS03285 ENOG4105EEX Two component transcriptional regulator (Winged helix family GSU80_RS03290 ENOG4105C08 Histidine kinase GSU80_RS03315 ENOG4105XIQ Protein of unknown function (DUF2517) GSU80_RS03330 ENOG41079JQ Membrane GSU80_RS03340 ENOG4106R09 GSU80_RS03365 ENOG4107SEY Conserved Protein GSU80_RS03370 ENOG4105CVP deoxyribo-dipyrimidine photolyase GSU80_RS03375 ENOG4105DUX Transporter GSU80_RS03380 ENOG4107QNR UPF0135 protein GSU80_RS03385 ENOG4105P4J Allophanate hydrolase, subunit 1 GSU80_RS03390 ENOG4107R7A Allophanate hydrolase subunit 2 GSU80_RS03395 ENOG4105E7W lamb ycsf family protein GSU80_RS03405 ENOG4108KK1 membrane protein AbrB duplication GSU80_RS03410 ENOG4108MY7 Fimbrial GSU80_RS03415 ENOG4108TTM chaperone GSU80_RS03420 ENOG4106PG1 outer membrane usher protein GSU80_RS03425 ENOG4106UBK fimbrial-like adhesin protein GSU80_RS03430 ENOG4105BZN citrate synthase GSU80_RS03440 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit GSU80_RS03445 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein GSU80_RS03450 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) GSU80_RS03455 ENOG4105E33 succinate dehydrogenase GSU80_RS03460 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 GSU80_RS03465 ENOG4105C7S Dehydrogenase GSU80_RS03475 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha GSU80_RS03480 ENOG4105FDP GntR family transcriptional regulator GSU80_RS03485 ENOG4105DM4 PTS System GSU80_RS03490 ENOG4105C8I hydrolase, family 38 GSU80_RS03495 ENOG4105C4M (Ubiquinol oxidase) subunit I GSU80_RS03500 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii GSU80_RS03510 ENOG4105KJB cyd operon protein YbgE GSU80_RS03515 ENOG4107YD3 Thioesterase GSU80_RS03520 ENOG4105E02 MotA TolQ exbB proton channel GSU80_RS03525 ENOG4105M8F Biopolymer transport protein exbD tolR GSU80_RS03530 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA GSU80_RS03540 ENOG4105KCK Peptidoglycan-associated lipoprotein GSU80_RS03545 ENOG4105UFD tol-pal system protein YbgF GSU80_RS03590 ENOG4106Z1T Nicotinamide Mononucleotide Transporter GSU80_RS03595 ENOG4105PGM cation diffusion facilitator family transporter GSU80_RS03600 ENOG4105JND homeobox protein GSU80_RS03605 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) GSU80_RS03620 ENOG4105NBR Pectinesterase GSU80_RS03625 ENOG4108I1J Integrase GSU80_RS03670 ENOG4108TFU terminase (Small subunit) GSU80_RS03715 ENOG4108V1U phospholipid-binding protein GSU80_RS03720 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) GSU80_RS03735 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) GSU80_RS03740 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) GSU80_RS03750 ENOG4105CHW UPF0052 protein GSU80_RS03760 ENOG4108RIR Molybdenum cofactor biosynthesis protein GSU80_RS03770 ENOG4105M00 molybdopterin converting factor, subunit 1 GSU80_RS03775 ENOG4108ZAF Molybdopterin GSU80_RS03780 ENOG4105HFZ Membrane GSU80_RS03785 ENOG410733J conserved inner membrane protein GSU80_RS03790 ENOG4107UXM Membrane GSU80_RS03795 ENOG4105DZQ phospholipase D Transphosphatidylase GSU80_RS03800 ENOG4105X23 Endonuclease Exonuclease phosphatase GSU80_RS03805 ENOG4105I9U inner membrane protein ybhQ GSU80_RS03810 ENOG4107QWP ABC-2 type transporter GSU80_RS03815 ENOG4107QWP ABC-2 type transporter GSU80_RS03820 ENOG4105CJ1 ABC, transporter GSU80_RS03830 ENOG4107MVR Transcriptional regulator GSU80_RS03835 ENOG4105C1J atp-dependent rna helicase GSU80_RS03840 ENOG4108UV1 cellular component movement GSU80_RS03845 ENOG4105DVT helicase GSU80_RS03850 ENOG4108MTB glycosyl transferase family GSU80_RS03855 ENOG4105DG4 malate L-lactate dehydrogenase GSU80_RS03860 ENOG4105VR4 UPF0379 protein ybiJ GSU80_RS03865 ENOG4105KSC Transcriptional regulator, TraR DksA family GSU80_RS03875 ENOG4108IU3 tonb-dependent siderophore receptor GSU80_RS03880 ENOG4105ZY9 UPF0379 protein ybiM GSU80_RS03890 ENOG4105D8X mechanosensitive ion channel GSU80_RS03895 ENOG4105CDA abc transporter atp-binding protein GSU80_RS03900 ENOG4105E5Q amino acid AbC transporter GSU80_RS03905 ENOG4107R0W ABC transporter GSU80_RS03915 ENOG4107AQZ Membrane GSU80_RS03925 ENOG4108T1M outer membrane protein x GSU80_RS03930 ENOG4108I6E Sulfatase GSU80_RS03940 ENOG4105KST dependent repressor GSU80_RS03945 ENOG4105F4P )-transporter GSU80_RS03950 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein GSU80_RS03955 ENOG4105C5H ABC transporter GSU80_RS03960 ENOG41072TH Protein of unknown function (DUF1479) GSU80_RS03965 ENOG4108HCJ Hydrolase GSU80_RS03970 ENOG4105C6N Formate acetyltransferase GSU80_RS03975 ENOG4105F1A Pyruvate formate-lyase GSU80_RS03980 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) GSU80_RS03985 ENOG4105D06 uba thif-type nad fad binding protein GSU80_RS03990 ENOG4105CVM Molybdenum cofactor synthesis domain protein GSU80_RS03995 ENOG4105D44 asparaginase GSU80_RS04000 ENOG4108JQ6 ABC transporter GSU80_RS04005 ENOG4105DEF Extracellular solute-binding protein, family 5 GSU80_RS04015 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component GSU80_RS04025 ENOG41064RH membrane protein YliF GSU80_RS04035 ENOG4105UFT Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway GSU80_RS04040 ENOG4105D8V Glucose sorbosone dehydrogenase GSU80_RS04045 ENOG4108TGY Glutathione S-transferase GSU80_RS04050 ENOG4105DZ1 carboxypeptidase GSU80_RS04055 ENOG4107FB0 transcriptional regulator DeoR family GSU80_RS04060 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase GSU80_RS04065 ENOG4107QF7 multi-drug GSU80_RS04075 ENOG4108HCJ Hydrolase GSU80_RS04080 ENOG4106UW1 Major Facilitator superfamily GSU80_RS04085 ENOG4108RFG Tetr family transcriptional regulator GSU80_RS04095 ENOG4108IYT Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) GSU80_RS04100 ENOG4105UPP uncharacterized protein ydcA GSU80_RS04110 ENOG4105MEH GSU80_RS04115 ENOG4105VZ1 Replication Protein GSU80_RS04140 ENOG4107RRE RNA-directed DNA polymerase GSU80_RS04145 ENOG4105ED4 portal protein GSU80_RS04210 ENOG4105PTU response to oxidative stress GSU80_RS04215 ENOG4108US3 tail fiber assembly GSU80_RS04235 ENOG4105ZTC transcriptional activator, Ogr delta GSU80_RS04245 ENOG4105GWF inner membrane protein YbjM GSU80_RS04250 ENOG41090BQ Glutaredoxin GSU80_RS04255 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress GSU80_RS04260 ENOG4108DBC nitroreductase GSU80_RS04270 ENOG4108RMJ sensory transduction regulator GSU80_RS04275 ENOG4107RUE extracellular solute-binding protein family 1 GSU80_RS04280 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) GSU80_RS04285 ENOG4105F38 ABC transporter, permease GSU80_RS04290 ENOG4105D38 putrescine abc transporter GSU80_RS04295 ENOG4105RBQ inner membrane protein ybjO GSU80_RS04305 ENOG4106TNF Periplasmic binding protein GSU80_RS04310 ENOG4105DMR ABC, transporter GSU80_RS04315 ENOG4105GBT ABC transporter GSU80_RS04320 ENOG4106PMH Extracellular solute-binding protein family 3 GSU80_RS04325 ENOG4105E5Z arginine transporter ATP-binding subunit GSU80_RS04330 ENOG41064MM (LipO)protein GSU80_RS04340 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase GSU80_RS04345 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase GSU80_RS04350 ENOG4105CGD Nad-dependent epimerase dehydratase GSU80_RS04355 ENOG4105C5W Aldolase GSU80_RS04360 ENOG4105C7K acetolactate synthase GSU80_RS04365 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) GSU80_RS04375 ENOG4105DWU Membrane GSU80_RS04380 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) GSU80_RS04385 ENOG4105CPB ATP-dependent endonuclease of the OLD family GSU80_RS04390 ENOG4108MJ5 VirK protein GSU80_RS04395 ENOG4105DJY efflux transporter, rnd family, mfp subunit GSU80_RS04400 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) GSU80_RS04405 ENOG4105VEQ Cold shock protein GSU80_RS04415 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit GSU80_RS04430 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) GSU80_RS04440 ENOG4108JJ8 (ABC) transporter GSU80_RS04445 ENOG4108JJ9 ABC, transporter GSU80_RS04450 ENOG4105C3M thioredoxin reductase GSU80_RS04455 ENOG4105EW9 transcriptional regulator AsnC family GSU80_RS04460 ENOG4105CNU cell division protein FtsK GSU80_RS04470 ENOG4105D1H recombination factor protein RarA GSU80_RS04480 ENOG4107QY8 reductase GSU80_RS04485 ENOG4105QAX Iron-sulfur GSU80_RS04490 ENOG4107KGK dmso reductase anchor subunit GSU80_RS04495 ENOG4105CHJ isochorismatase hydrolase GSU80_RS04505 ENOG4105E5D amino acid GSU80_RS04510 ENOG410642W LysR family Transcriptional regulator GSU80_RS04515 ENOG4108X0B nad(p)h dehydrogenase (quinone) GSU80_RS04520 ENOG4105F1A Pyruvate formate-lyase GSU80_RS04525 ENOG4105C6N Formate acetyltransferase GSU80_RS04530 ENOG4105TMB Formate nitrite transporter GSU80_RS04535 ENOG4105DDY UPF0142 protein ycaO GSU80_RS04540 ENOG4107VMU Membrane GSU80_RS04555 ENOG4108K0D peptidase, M48 GSU80_RS04565 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) GSU80_RS04575 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 GSU80_RS04580 ENOG4105BZ1 (ABC) transporter GSU80_RS04585 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) GSU80_RS04590 ENOG4105T0Z Conserved Protein GSU80_RS04605 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups GSU80_RS04610 ENOG4107S90 membrAne GSU80_RS04615 ENOG4106371 Methyltransferase GSU80_RS04625 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) GSU80_RS04630 ENOG4105DUC Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity) GSU80_RS04635 ENOG4105DIT ErfK YbiS YcfS YnhG family protein GSU80_RS04640 ENOG4105EAQ (twin-arginine translocation) pathway signal GSU80_RS04645 ENOG4105C5X domain protein GSU80_RS04650 ENOG4105CGF Aromatic amino acid aminotransferase GSU80_RS04655 ENOG4105FCK Membrane GSU80_RS04670 ENOG4105CD8 aminopeptidase N GSU80_RS04675 ENOG4105E2Y ABC, transporter GSU80_RS04680 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component GSU80_RS04690 ENOG4105GVF (ABC) transporter GSU80_RS04695 ENOG4108UZX fmn reductase GSU80_RS04700 ENOG41071VI Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. ElfA is the major fimbrial subunit produced by this operon GSU80_RS04705 ENOG4106JJN Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. Could be required for the biogenesis of the ElfA fimbriae GSU80_RS04710 ENOG4105CW0 outer membrane usher protein GSU80_RS04715 ENOG4108MDY Fimbrial GSU80_RS04720 ENOG4105Q7J Fimbrial GSU80_RS04725 ENOG4105MX3 Fimbrial GSU80_RS04730 ENOG4106PH7 chaperone GSU80_RS04740 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) GSU80_RS04745 ENOG4105QVC MOSC domain-containing protein GSU80_RS04750 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) GSU80_RS04755 ENOG4105C5H ABC transporter GSU80_RS04760 ENOG4105F1S paraquat-inducible protein a GSU80_RS04765 ENOG4105DY2 Paraquat-inducible protein b GSU80_RS04770 ENOG4108Q2G (LipO)protein GSU80_RS04775 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) GSU80_RS04785 ENOG4105DAN ATP-dependent protease GSU80_RS04795 ENOG4105UYK outer membrane protein a GSU80_RS04805 ENOG4108RZ1 DNA transformation protein GSU80_RS04810 ENOG4105EM2 membrane GSU80_RS04815 ENOG410901E Membrane GSU80_RS04820 ENOG41088T4 Helicase IV GSU80_RS04835 ENOG4105K4P CoA-binding domain protein GSU80_RS04850 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 GSU80_RS04860 ENOG4108MN8 Membrane GSU80_RS04870 ENOG4105E3S small subunit GSU80_RS04875 ENOG4105DPX Hydrogenase, large subunit GSU80_RS04880 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit GSU80_RS04885 ENOG4108USZ hydrogenase GSU80_RS04890 ENOG4108VXY Hydrogenase-1 operon protein HyaE GSU80_RS04895 ENOG4105MVP hydrogenase-1 operon protein HyaF GSU80_RS04900 ENOG4105C4M (Ubiquinol oxidase) subunit I GSU80_RS04905 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii GSU80_RS04915 ENOG4105D6F Phosphatase GSU80_RS04920 ENOG4108F2G Chain length determinant protein GSU80_RS04925 ENOG4107ZF2 Phosphatase GSU80_RS04930 ENOG4105DAY polysaccharide export protein GSU80_RS04935 ENOG4105E3R (LipO)protein GSU80_RS04940 ENOG4108W78 Pfam:DUF1017 GSU80_RS04945 ENOG4108Y9B (LipO)protein GSU80_RS04955 ENOG41060EU Cold shock-like protein GSU80_RS04960 ENOG4105VEQ Cold shock protein GSU80_RS04975 ENOG4106H71 Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation GSU80_RS04980 ENOG4105HEE Binding Domain protein GSU80_RS04985 ENOG4105BZU Histidine kinase GSU80_RS04990 ENOG4108SV3 Tmao reductase system periplasmic protein tort GSU80_RS04995 ENOG4106WF9 DNA-binding transcriptional regulator TorR GSU80_RS05000 ENOG4105CUW cytochrome C-TYPE protein GSU80_RS05005 ENOG4107QY8 reductase GSU80_RS05030 ENOG4105D6F Phosphatase GSU80_RS05035 ENOG4105XH3 GSU80_RS05045 ENOG4105XF5 Escherichia coli IMT2125 genomic chromosome, IMT2125 GSU80_RS05050 ENOG4105C2W permease GSU80_RS05065 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) GSU80_RS05075 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) GSU80_RS05080 ENOG4105EQP Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity) GSU80_RS05085 ENOG4108R86 Transcriptional regulator GSU80_RS05090 ENOG4105C26 Dehydrogenase GSU80_RS05100 ENOG4105CK7 Sodium proline symporter GSU80_RS05105 ENOG4105EKT )-iron permease GSU80_RS05110 ENOG410650H (LipO)protein GSU80_RS05115 ENOG4105DBE peroxidase GSU80_RS05120 ENOG4105D5M phosphate starvation-inducible protein GSU80_RS05125 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD GSU80_RS05130 ENOG4105CND Glycosyl transferase, family 2 GSU80_RS05135 ENOG4107BJW polysaccharide deacetylase GSU80_RS05140 ENOG4108TUY outer membrane protein PgaA GSU80_RS05145 ENOG4105BZU Histidine kinase GSU80_RS05170 ENOG4107XHZ cytoplasmic chaperone TorD family protein GSU80_RS05175 ENOG4108UQ5 membrane protein YcdZ GSU80_RS05180 ENOG4105P8Q Curli production assembly transport component CsgG GSU80_RS05185 ENOG4108WYR Curli production assembly transport component, CsgF GSU80_RS05190 ENOG4108XDW curli assembly protein CsgE GSU80_RS05195 ENOG41086KC Transcriptional regulator GSU80_RS05200 ENOG4108U0V Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin. The minor subunit is the nucleation component of curlin monomers GSU80_RS05205 ENOG4105G76 Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin GSU80_RS05220 ENOG4108UVJ appr-1-p processing domain protein GSU80_RS05225 ENOG4107RZC phospholipase d GSU80_RS05240 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) GSU80_RS05245 ENOG4105NAC (LipO)protein GSU80_RS05250 ENOG4108W47 Acidic protein msyB GSU80_RS05260 ENOG4105D1S lipid A biosynthesis GSU80_RS05270 ENOG4108YYC ycei family GSU80_RS05275 ENOG4105DS1 cytochrome b561 GSU80_RS05280 ENOG4106974 biofilm formation GSU80_RS05290 ENOG4105PVA Biofilm formation regulatory protein BssS GSU80_RS05295 ENOG4105MEA DNA damage-inducible protein i GSU80_RS05305 ENOG4105F3T (LipO)protein GSU80_RS05310 ENOG4105E9S glutaredoxin 2 GSU80_RS05320 ENOG4105D9U N-acetyltransferase GSU80_RS05330 ENOG4105EP9 oxidoreductase GSU80_RS05335 ENOG4105CJR Integral membrane protein (MviN GSU80_RS05340 ENOG4105QVD Flagella synthesis protein FlgN GSU80_RS05345 ENOG4105M9M anti-sigma28 factor FlgM GSU80_RS05350 ENOG4105CKS Flagella basal body P-ring formation protein flgA GSU80_RS05355 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) GSU80_RS05360 ENOG4108ZC9 flagellar basal-body rod protein flgc GSU80_RS05365 ENOG4105W00 Flagellar hook capping protein GSU80_RS05370 ENOG4105BZE flagellar hook protein, FlgE GSU80_RS05375 ENOG4108KPB Flagellar basal-body rod protein FlgF GSU80_RS05380 ENOG4105CGA flagellar basal-body rod protein FlgG GSU80_RS05395 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj GSU80_RS05400 ENOG4105E1Q flagellar hook-associated protein GSU80_RS05405 ENOG4105DTJ flagellar hook-associated protein GSU80_RS05410 ENOG4107QQB Ribonuclease E GSU80_RS05415 ENOG4105EI2 Pseudouridine synthase GSU80_RS05420 ENOG4108UHJ MAF-like protein GSU80_RS05425 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein GSU80_RS05445 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase GSU80_RS05450 ENOG4105CHR reductase GSU80_RS05455 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) GSU80_RS05460 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) GSU80_RS05465 ENOG4105YAZ 4-amino-4-deoxychorismate lyase GSU80_RS05470 ENOG4105HHA aminodeoxychorismate lyase GSU80_RS05480 ENOG4107QRG dna polymerase iii GSU80_RS05485 ENOG4105F8V Hydrolase, tatD family GSU80_RS05490 ENOG4105CI1 PTS System GSU80_RS05495 ENOG4105CNM Receptor GSU80_RS05500 ENOG4105K59 histidine triad (HIT) protein GSU80_RS05505 ENOG41090DQ Lipoprotein GSU80_RS05510 ENOG4108WEF Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity) GSU80_RS05530 ENOG4105CEP NADH dehydrogenase GSU80_RS05535 ENOG4107MBR 17 kDa surface antigen GSU80_RS05540 ENOG4108IND Tetr family transcriptional regulator GSU80_RS05545 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction GSU80_RS05550 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein GSU80_RS05555 ENOG4108JA2 transcriptioN-repair coupling factor GSU80_RS05560 ENOG4105IQC Inner membrane protein YcfT GSU80_RS05565 ENOG4105D60 lipoprotein releasing system transmembrane protein GSU80_RS05570 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) GSU80_RS05575 ENOG4105D60 lipoprotein releasing system transmembrane protein GSU80_RS05595 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) GSU80_RS05610 ENOG4107RUE extracellular solute-binding protein family 1 GSU80_RS05615 ENOG4105D38 putrescine abc transporter GSU80_RS05620 ENOG4105F38 ABC transporter, permease GSU80_RS05635 ENOG4105EZE Cupin 4 family protein GSU80_RS05640 ENOG4105IFJ Histidine kinase GSU80_RS05645 ENOG4105XJC Two component transcriptional regulator (Winged helix family GSU80_RS05650 ENOG4107QTF adenylosuccinate lyase GSU80_RS05670 ENOG4108R99 pseudouridine synthase GSU80_RS05675 ENOG4108HMX isocitrate dehydrogenase (NADP) GSU80_RS05690 ENOG41064WM Uncharacterized protein YcgX GSU80_RS05695 ENOG4108XDN Transcriptional regulator GSU80_RS05700 ENOG4105BZU Histidine kinase GSU80_RS05705 ENOG4105WKE Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. Partially antagonizes the activities of YmgA and AriR, proteins that, via the Rcs phosphorelay, promote the synthesis of colanic acid, an exopolysaccharide and matrix component GSU80_RS05710 ENOG41077SS Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. May serve to stimulate biofilm maturation, probably via the Rcs phosphorelay. Mild overexpression at 16 degrees Celsius increases the production of colanic acid, an exopolysaccharide and matrix component, and reduces adhesive curli fimbriae expression. Both of these effects require RcsB GSU80_RS05720 ENOG410738I uncharacterized protein ymgC GSU80_RS05725 ENOG4105BZU Histidine kinase GSU80_RS05745 ENOG410658X GSU80_RS05780 ENOG4107QMS site-determining protein GSU80_RS05790 ENOG4105S66 prophage protein GSU80_RS05795 ENOG41066UD Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium GSU80_RS05805 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase GSU80_RS05820 ENOG4105KT5 UmuD protein GSU80_RS05825 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) GSU80_RS05830 ENOG410635M Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity) GSU80_RS05845 ENOG4105ED1 spovr family GSU80_RS05855 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) GSU80_RS05865 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A GSU80_RS05875 ENOG4108T7K Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity) GSU80_RS05895 ENOG4105VDH Dihydroxyacetone kinase GSU80_RS05900 ENOG4108UTZ Dihydroxyacetone kinase GSU80_RS05905 ENOG4105CMT Dihydroxyacetone kinase GSU80_RS05910 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family GSU80_RS05915 ENOG4105I1J Autotransporter GSU80_RS05920 ENOG4105C3G gtp-binding protein GSU80_RS05930 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria GSU80_RS05935 ENOG4105CHH sulfate transporter GSU80_RS05940 ENOG4105C5T Phosphoribosyl pyrophosphate synthase GSU80_RS05965 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) GSU80_RS05970 ENOG4108YY7 Invasion gene expression up-regulator SirB GSU80_RS05975 ENOG41063JG Transcriptional regulator GSU80_RS06000 ENOG4105EWV Sodium calcium exchanger membrane region GSU80_RS06005 ENOG4105WS7 Cation transport regulator GSU80_RS06010 ENOG4108NH8 Cation transport protein GSU80_RS06015 ENOG41090EX DsrE family GSU80_RS06020 ENOG4105ID0 Putative invasin GSU80_RS06025 ENOG4105WH1 Two component transcriptional regulator luxr family GSU80_RS06030 ENOG4105BZU Histidine kinase GSU80_RS06035 ENOG4105DQQ Major facilitator superfamily MFS_1 GSU80_RS06040 ENOG4105CRU nitrate reductase, alpha subunit GSU80_RS06045 ENOG4108IUE nitrate reductase beta subunit GSU80_RS06050 ENOG4105R3A Nitrate reductase GSU80_RS06055 ENOG41076YT nitrate reductase, gamma subunit GSU80_RS06080 ENOG4105CIY formyltetrahydrofolate deformylase GSU80_RS06090 ENOG4105D78 K07001 NTE family protein GSU80_RS06095 ENOG4105I93 response regulator GSU80_RS06100 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase GSU80_RS06105 ENOG4108SAU DNA-binding protein H-ns GSU80_RS06110 ENOG4107104 thymidine kinase GSU80_RS06115 ENOG4108EKI Dehydrogenase GSU80_RS06120 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein GSU80_RS06125 ENOG4108J59 Extracellular solute-binding protein, family 5 GSU80_RS06135 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component GSU80_RS06140 ENOG4105C3U ABC transporter GSU80_RS06145 ENOG4108JQ7 (ABC) transporter GSU80_RS06165 ENOG4107SVH Potassium channel protein GSU80_RS06170 ENOG4105K9H YciI-like protein GSU80_RS06175 ENOG410822N TonB family GSU80_RS06180 ENOG4105NAU thioesterase Superfamily protein GSU80_RS06200 ENOG4105EIF outer membrane protein W GSU80_RS06205 ENOG4108N8X transition metal ion binding GSU80_RS06210 ENOG4108Z9Z response to DNA damage stimulus GSU80_RS06230 ENOG4105DK0 Indole-3-glycerol phosphate synthase GSU80_RS06235 ENOG4108EFP Anthranilate synthase component II GSU80_RS06240 ENOG4105CRQ synthase (Component I) GSU80_RS06250 ENOG4105DB7 PHP domain protein GSU80_RS06255 ENOG4107RTD sua5 ycio yrdc ywlc family protein GSU80_RS06275 ENOG4105FE9 pseudouridine synthase GSU80_RS06280 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase GSU80_RS06285 ENOG4105UBK short-chain dehydrogenase reductase GSU80_RS06290 ENOG4105ERU peptidase GSU80_RS06295 ENOG4105RKX Protein of unknown function (DUF2498) GSU80_RS06300 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) GSU80_RS06305 ENOG4107R11 Transcriptional regulator GSU80_RS06325 ENOG4107QM5 aconitate hydratase GSU80_RS06335 ENOG4105EYK Phosphatidylglycerophosphatase B GSU80_RS06340 ENOG4105Q4A inner membrane protein yciS GSU80_RS06345 ENOG4105CFV Tetratricopeptide repeat protein GSU80_RS06355 ENOG4108ZJT translation initiation factor, Sui1 GSU80_RS06360 ENOG41061RM osmotically inducible lipoprotein GSU80_RS06365 ENOG4105N2W Transcriptional regulator GSU80_RS06375 ENOG4105BZU Histidine kinase GSU80_RS06390 ENOG4105Q4T oxidoreductase GSU80_RS06395 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH GSU80_RS06400 ENOG4105WDY DNA (cytosine-5-)-methyltransferase GSU80_RS06405 ENOG4108JQ2 peptide transport system atp-binding protein GSU80_RS06410 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein GSU80_RS06415 ENOG4108EU3 peptide transport system, permease GSU80_RS06420 ENOG4108I5W peptide transport system, permease protein GSU80_RS06425 ENOG4108HIY periplasmic GSU80_RS06430 ENOG4105N0E Protein of unknown function (DUF2543) GSU80_RS06435 ENOG4105CUB amino acid GSU80_RS06445 ENOG4105CFQ glutamine synthetase GSU80_RS06450 ENOG4108Z86 Glutamine amidotransferase GSU80_RS06455 ENOG4107VRI Transcriptional regulator GSU80_RS06460 ENOG4105C26 Dehydrogenase GSU80_RS06465 ENOG4105CJP fad dependent oxidoreductase GSU80_RS06470 ENOG4108JPW Aminotransferase GSU80_RS06475 ENOG4105E51 psp operon transcriptional activator GSU80_RS06480 ENOG41087YS Phage shock protein A GSU80_RS06485 ENOG4105YYT phage shock protein B GSU80_RS06490 ENOG4105FM1 phage shock protein C GSU80_RS06495 ENOG4105NNG Peripheral inner membrane phage-shock protein GSU80_RS06500 ENOG4105K8Z Phage shock protein GSU80_RS06505 ENOG4107QW3 Sucrose phosphorylase GSU80_RS06510 ENOG4105WEM extracellular solute-binding protein GSU80_RS06515 ENOG4105HS6 binding-protein-dependent transport systems inner membrane Component GSU80_RS06520 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component GSU80_RS06525 ENOG4107RRD Dehydrogenase GSU80_RS06530 ENOG4107TYA transient receptor potential locus GSU80_RS06535 ENOG4105CK5 oxidoreductase GSU80_RS06540 ENOG4105C71 hydrolase family 65, central catalytic GSU80_RS06545 ENOG4107URF beta-phospho-glucomutase GSU80_RS06550 ENOG4108IJ9 (ABC) transporter GSU80_RS06555 ENOG4107EFV Outer membrane protein G GSU80_RS06560 ENOG4105FKQ transcriptional regulator GSU80_RS06565 ENOG4105CM6 amino acid regulated cytosolic protein GSU80_RS06575 ENOG4108JU8 Transcriptional regulator GSU80_RS06580 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) GSU80_RS06585 ENOG4107S8C mandelate racemase muconate lactonizing GSU80_RS06590 ENOG4105KXI murein peptide amidase A GSU80_RS06605 ENOG4105ENX hydrolase GSU80_RS06610 ENOG4105EQ2 LysR family Transcriptional regulator GSU80_RS06615 ENOG4107QSI ABC, transporter GSU80_RS06620 ENOG4105D64 Mechanosensitive ion channel GSU80_RS06625 ENOG4105S5I Membrane GSU80_RS06630 ENOG4105Q9Y Universal stress protein GSU80_RS06640 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) GSU80_RS06645 ENOG4105CFC Transporter GSU80_RS06650 ENOG4107RT5 aminobenzoyl-glutamate utilization protein B GSU80_RS06655 ENOG4105CH2 amidohydrolase GSU80_RS06660 ENOG4106KR7 LysR family Transcriptional regulator GSU80_RS06665 ENOG4108DG9 Smr protein MutS2 GSU80_RS06670 ENOG4105BZU Histidine kinase GSU80_RS06680 ENOG4105C1J atp-dependent rna helicase GSU80_RS06685 ENOG4105CB3 Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity) GSU80_RS06690 ENOG4107R08 Integrase GSU80_RS06695 ENOG4107160 Rac prophage GSU80_RS06700 ENOG41070YT Rac prophage GSU80_RS06705 ENOG4106YAH restriction alleviation and modification enhancement GSU80_RS06710 ENOG4108PNI recT protein GSU80_RS06725 ENOG4107C82 Rac prophage GSU80_RS06745 ENOG4105QFS Lysis protein S homolog from lambdoid prophage GSU80_RS06770 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) GSU80_RS06775 ENOG4108ES9 ParB domain protein nuclease GSU80_RS06800 ENOG4105MN3 Resolvase GSU80_RS06805 ENOG4105W3V DNA-binding, transcriptional regulator GSU80_RS06820 ENOG4108RW8 Universal stress protein F GSU80_RS06825 ENOG4105FCK Membrane GSU80_RS06830 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) GSU80_RS06840 ENOG41090X5 Heat shock protein hslJ GSU80_RS06845 ENOG4105C5I Dehydrogenase GSU80_RS06850 ENOG4107H52 Dicarboxylate transport GSU80_RS06855 ENOG410689M (LipO)protein GSU80_RS06860 ENOG4105WXT Conserved Protein GSU80_RS06865 ENOG4108WFR AraC Family Transcriptional Regulator GSU80_RS06870 ENOG4105C26 Dehydrogenase GSU80_RS06895 ENOG4108UMZ Cdp-alcohol phosphatidyltransferase GSU80_RS06900 ENOG4108HPI phosphatidate Cytidylyltransferase GSU80_RS06905 ENOG4105E8V Alpha Beta Hydrolase Fold protein GSU80_RS06910 ENOG41077RS Phosphatase GSU80_RS06920 ENOG4105CQ7 ATP-dependent helicase GSU80_RS06925 ENOG4107DB1 DUF218 domain GSU80_RS06930 ENOG4105C26 Dehydrogenase GSU80_RS06935 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase GSU80_RS06945 ENOG4105CPW cytochrome b561 GSU80_RS06950 ENOG4105UPP uncharacterized protein ydcA GSU80_RS06955 ENOG4107NK6 Hok/gef family GSU80_RS06960 ENOG4105C8Q Methyl-accepting chemotaxis GSU80_RS06965 ENOG4105DDW LysR family Transcriptional regulator GSU80_RS06970 ENOG4105E32 cytoplasmic protein GSU80_RS06980 ENOG4105Z2P Protein of unknown function (DUF465) GSU80_RS06985 ENOG4108Z9I -acetyltransferase GSU80_RS06990 ENOG4107WE3 acetyltransferase YdcK GSU80_RS06995 ENOG4108NKP c4-dicarboxylate transporter malic acid transport protein GSU80_RS07000 ENOG41088CC tellurite resistance protein tehB GSU80_RS07005 ENOG4108KKZ (LipO)protein GSU80_RS07015 ENOG4105D7V transposase GSU80_RS07020 ENOG4105DKK Benzoate GSU80_RS07025 ENOG4108JCI Transcriptional regulator GSU80_RS07030 ENOG4105CFP Peptidase U32 GSU80_RS07035 ENOG4105RR0 Protein of unknown function (DUF2554) GSU80_RS07045 ENOG4105PF0 Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin GSU80_RS07050 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family GSU80_RS07055 ENOG4107TYH extracellular solute-binding protein family 1 GSU80_RS07060 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) GSU80_RS07065 ENOG4105D81 ABC transporter, permease GSU80_RS07070 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component GSU80_RS07085 ENOG410654E Membrane GSU80_RS07090 ENOG4105R71 cytoplasmic protein GSU80_RS07095 ENOG4108T9Y Inner membrane protein ydcZ GSU80_RS07100 ENOG4108Z7F N-acetyltransferase GSU80_RS07105 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein GSU80_RS07110 ENOG4108WYP Transcriptional regulator GSU80_RS07115 ENOG4105CHB tonB-dependent Receptor GSU80_RS07120 ENOG4108NS2 receptor GSU80_RS07125 ENOG4105C85 amino acid GSU80_RS07130 ENOG4108N27 Glutathione S-transferase GSU80_RS07175 ENOG4108MEJ flavin reductase domain protein GSU80_RS07180 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase GSU80_RS07190 ENOG4105D0D Nitrate reductase 2, gamma subunit GSU80_RS07195 ENOG4108NZN Respiratory nitrate reductase 2 delta chain GSU80_RS07200 ENOG4108IUE nitrate reductase beta subunit GSU80_RS07205 ENOG4105CRU nitrate reductase, alpha subunit GSU80_RS07210 ENOG4107QND Nitrite extrusion protein GSU80_RS07225 ENOG4105RPH Inner membrane protein YddG GSU80_RS07235 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein GSU80_RS07240 ENOG4108MG3 formate dehydrogenase GSU80_RS07245 ENOG41084S7 Plasmid maintenance system antidote protein GSU80_RS07250 ENOG4105DQ4 alcohol dehydrogenase GSU80_RS07260 ENOG4107AV5 Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein GSU80_RS07265 ENOG4105TPS biofilm-dependent modulation protein GSU80_RS07270 ENOG4108Z9K Osmotically inducible protein GSU80_RS07275 ENOG4107H6U ABC transporter GSU80_RS07280 ENOG4105C3U ABC transporter GSU80_RS07285 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component GSU80_RS07290 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component GSU80_RS07295 ENOG4105DEF Extracellular solute-binding protein, family 5 GSU80_RS07300 ENOG4108UQS dipeptidase GSU80_RS07305 ENOG4105BZU Histidine kinase GSU80_RS07315 ENOG4105F32 YngK protein GSU80_RS07320 ENOG4105E5D amino acid GSU80_RS07325 ENOG4105CVK Glutamate decarboxylase GSU80_RS07330 ENOG4107RAN Peptidase, M16 GSU80_RS07335 ENOG4105PE1 Receptor GSU80_RS07340 ENOG4105CQ0 ABC transporter GSU80_RS07350 ENOG4105C4X radical SAM domain protein GSU80_RS07355 ENOG4105ENH Sulfatase GSU80_RS07360 ENOG4105Z68 AraC Family Transcriptional Regulator GSU80_RS07370 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit GSU80_RS07375 ENOG4106PIH fimbrial-like protein ydeQ GSU80_RS07380 ENOG4106318 fimbrial-like protein YdeR GSU80_RS07385 ENOG4108WDE Fimbrial protein GSU80_RS07395 ENOG4105CW0 outer membrane usher protein GSU80_RS07400 ENOG4105CW0 outer membrane usher protein GSU80_RS07410 ENOG4108RQP Major type 1 subunit fimbrin GSU80_RS07415 ENOG4105CAF HipA N-terminal domain protein GSU80_RS07420 ENOG41061P8 Persistence to inhibition of murein or DNA biosynthesis regulatory protein GSU80_RS07435 ENOG4105D4B ABC, transporter GSU80_RS07445 ENOG4105K34 Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the cleavage of phosphorylated 4,5- dihydroxy-2,3-pentanedione (P-DPD) to 2-phosphoglycolic acid (PG) and another three-carbon compound GSU80_RS07455 ENOG4105FFC UPF0187 protein GSU80_RS07460 ENOG4107QZW Altronate oxidoreductase GSU80_RS07465 ENOG4105BZU Histidine kinase GSU80_RS07470 ENOG4105M0C cytoplasmic protein GSU80_RS07475 ENOG4105CSV Glutaminase GSU80_RS07480 ENOG4105C26 Dehydrogenase GSU80_RS07485 ENOG4105EGI Transcriptional regulator GSU80_RS07515 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes GSU80_RS07520 ENOG4108XW0 May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF GSU80_RS07525 ENOG4106DNR multiple antibiotic resistance protein GSU80_RS07530 ENOG4108594 Permease of the drug metabolite transporter GSU80_RS07535 ENOG4105E5W Transporter GSU80_RS07545 ENOG4105FSR swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria GSU80_RS07550 ENOG4108YDI single-species biofilm formation on inanimate substrate GSU80_RS07555 ENOG4108WTK competence damage-inducible protein GSU80_RS07560 ENOG4105DGW oligopeptidase A GSU80_RS07565 ENOG4105EMU Dehydrogenase GSU80_RS07570 ENOG4107XBN GntR Family Transcriptional Regulator GSU80_RS07575 ENOG41061EV selenium-binding protein YdfZ GSU80_RS07580 ENOG4105DEI Mannitol dehydrogenase GSU80_RS07595 ENOG4105W3V DNA-binding, transcriptional regulator GSU80_RS07600 ENOG4105MN3 Resolvase GSU80_RS07650 ENOG4105HRS Antitermination protein GSU80_RS07655 ENOG4108MXB Protein of unknown function (DUF968) GSU80_RS07655 ENOG4108MXB Protein of unknown function (DUF968) GSU80_RS07670 ENOG4105WI6 cell killing protein encoded within cryptic prophage GSU80_RS07685 ENOG4105YQ0 GSU80_RS07700 ENOG41087BU transcriptional repressor DicA GSU80_RS07725 ENOG4106G8A Qin prophage GSU80_RS07750 ENOG4105CPQ Dehydrogenase GSU80_RS07755 ENOG4105CXK mandelate racemase muconate lactonizing GSU80_RS07770 ENOG4108MK9 spermidine N(1)-acetyltransferase GSU80_RS07780 ENOG4105KBG Protein of unknown function (DUF1161) GSU80_RS07785 ENOG4107QY8 reductase GSU80_RS07790 ENOG4105C3J Cysteine desulfurase GSU80_RS07795 ENOG4105QAX Iron-sulfur GSU80_RS07800 ENOG4107KGK dmso reductase anchor subunit GSU80_RS07805 ENOG4108NEM leader-binding protein dmsD GSU80_RS07815 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) GSU80_RS07820 ENOG4105DAG ROK family GSU80_RS07825 ENOG4106NZI LysR family Transcriptional regulator GSU80_RS07830 ENOG4105D94 Major Facilitator Superfamily GSU80_RS07845 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap GSU80_RS07865 ENOG4105DSF transport protein GSU80_RS07870 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) GSU80_RS07875 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) GSU80_RS07880 ENOG4105C5D exported protein GSU80_RS07885 ENOG4105D5Q Arginine ornithine antiporter GSU80_RS07890 ENOG410642E Short chain dehydrogenase GSU80_RS07895 ENOG4105RA2 Membrane GSU80_RS07900 ENOG4107EXC regulatoR GSU80_RS07905 ENOG4105JJR Histidine kinase GSU80_RS07915 ENOG4105C9Q fumarate hydratase class II GSU80_RS07920 ENOG4107GFK fumarate GSU80_RS07925 ENOG4105EIP mannose-6-phosphate isomerase GSU80_RS07930 ENOG4106J39 exported protein GSU80_RS07935 ENOG4108QNI outer membrane porin protein GSU80_RS07940 ENOG4105CT4 transporter GSU80_RS07945 ENOG4105CNT hydrolase family 2 GSU80_RS07950 ENOG4105XEA Tetr family transcriptional regulator GSU80_RS07955 ENOG4107ZQV short-chain dehydrogenase reductase GSU80_RS07960 ENOG4107P2S Transcriptional regulator GSU80_RS07965 ENOG4105CI1 PTS System GSU80_RS07970 ENOG4105C87 Aminotransferase class I and II GSU80_RS07980 ENOG4105D9R oxidoreductase GSU80_RS07985 ENOG4106C6R beta-lactam resistance protein GSU80_RS07990 ENOG4105QZ5 OriC-binding nucleoid-associated protein GSU80_RS07995 ENOG4105M9B inner membrane protein ydgK GSU80_RS08020 ENOG4108UQQ Electron transport complex GSU80_RS08030 ENOG4105CSM endonuclease III GSU80_RS08035 ENOG4105DUX Transporter GSU80_RS08040 ENOG4108K3A Glutathione S-transferase GSU80_RS08045 ENOG4107XGF functions in a salvage pathway. Uses pyridoxamine (By similarity) GSU80_RS08060 ENOG410642K Lysozyme inhibitor GSU80_RS08070 ENOG4108XTF Outer Membrane Lipoprotein GSU80_RS08085 ENOG4105Y49 secretion protein, HlyD family GSU80_RS08090 ENOG4105DSW Fusaric acid resistance protein GSU80_RS08095 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) GSU80_RS08100 ENOG4107RGM aldo keto reductase GSU80_RS08105 ENOG4105XZD Fe-S protein GSU80_RS08110 ENOG4108WUH Transcriptional regulator, TetR family GSU80_RS08115 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase GSU80_RS08120 ENOG4108UYE Lactoylglutathione lyase GSU80_RS08130 ENOG4107QRT dEAD DEAH box helicase GSU80_RS08135 ENOG4105M2J Glutaredoxin GSU80_RS08140 ENOG4105K4H Nlp p60 protein GSU80_RS08145 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) GSU80_RS08150 ENOG4105F27 Major Facilitator GSU80_RS08165 ENOG4105F52 Transcriptional regulator GSU80_RS08170 ENOG4105CZQ inner membrane transport protein YdhC GSU80_RS08175 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase GSU80_RS08180 ENOG4108R6K riboflavin synthase, subunit alpha GSU80_RS08205 ENOG4105N0V mono-oxygenase ydhR GSU80_RS08210 ENOG4108KTU conserved protein with FAD NAD(P)-binding domain GSU80_RS08215 ENOG4108Y7C Conserved Protein GSU80_RS08220 ENOG4108NWD Cytochrome GSU80_RS08225 ENOG4108393 oxidoreductase Fe-S subunit GSU80_RS08230 ENOG4105JVW GSU80_RS08235 ENOG4105WE2 aldehyde ferredoxin oxidoreductase GSU80_RS08240 ENOG4108PU5 4fe-4S ferredoxin, iron-sulfur binding domain protein GSU80_RS08245 ENOG4105RFR Protein of unknown function (DUF2767) GSU80_RS08250 ENOG4105CA9 Pyruvate kinase GSU80_RS08255 ENOG4105KMX major outer membrane lipoprotein GSU80_RS08260 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein GSU80_RS08275 ENOG4105JRK feS assembly protein SufD GSU80_RS08280 ENOG4105C3K feS assembly ATPase SufC GSU80_RS08285 ENOG4105DIW FeS assembly protein SUFB GSU80_RS08290 ENOG410671Z uncharacterized protein ydiH GSU80_RS08295 ENOG4105KA0 thioesterase Superfamily protein GSU80_RS08300 ENOG4105CQB FAD linked oxidase domain protein GSU80_RS08305 ENOG4105IPI Membrane GSU80_RS08315 ENOG4105SUA Ydil protein GSU80_RS08325 ENOG4105EMV Major Facilitator GSU80_RS08340 ENOG4107R0K CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) GSU80_RS08345 ENOG4105C1G acyl-Coa dehydrogenase GSU80_RS08350 ENOG4105W4W Transcriptional regulator GSU80_RS08355 ENOG4105CV7 Electron transfer flavoprotein GSU80_RS08360 ENOG4105C10 Electron transfer flavoprotein GSU80_RS08365 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase GSU80_RS08370 ENOG41090P5 ferredoxin-like protein GSU80_RS08375 ENOG4105CEY Amp-dependent synthetase and ligase GSU80_RS08380 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) GSU80_RS08390 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) GSU80_RS08395 ENOG4106EDX Hemin uptake protein GSU80_RS08410 ENOG4108QBX (LipO)protein GSU80_RS08420 ENOG4108V06 Glutathione peroxidase GSU80_RS08435 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) GSU80_RS08450 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) GSU80_RS08455 ENOG41082NX 50s ribosomal protein l35 GSU80_RS08480 ENOG4108NE3 Salt-induced outer membrane protein GSU80_RS08485 ENOG4105DE4 1-phosphofructokinase GSU80_RS08490 ENOG4105P10 Uncharacterized protein ydiZ GSU80_RS08495 ENOG4105FGM Fructosamine kinase GSU80_RS08500 ENOG4107PN8 YfeABCD locus regulator GSU80_RS08505 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 GSU80_RS08510 ENOG4107K5X Membrane-bound metal-dependent hydrolase GSU80_RS08515 ENOG4108ETY sodium dicarboxylate symporter GSU80_RS08530 ENOG4105CH6 catalase GSU80_RS08540 ENOG4105F8D glycoside hydrolase family 4 GSU80_RS08545 ENOG4105EZV Transcriptional regulator GSU80_RS08550 ENOG4105VCP PTS System GSU80_RS08555 ENOG4105CK1 PTS System GSU80_RS08560 ENOG4105VZJ PTS System GSU80_RS08565 ENOG4105KKI DNA-binding transcriptional activator OsmE GSU80_RS08575 ENOG4105DKD Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity) GSU80_RS08585 ENOG4108SPG Periplasmic Protein GSU80_RS08605 ENOG4105F4X arginine GSU80_RS08615 ENOG4105CGK Exodeoxyribonuclease III GSU80_RS08620 ENOG4108RSN SNARE associated Golgi GSU80_RS08625 ENOG4108KCW iron-sulfur cluster binding GSU80_RS08630 ENOG4108N5C SNARE associated Golgi protein-related protein GSU80_RS08635 ENOG4107ZN8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) GSU80_RS08640 ENOG4105VNH ABC transporter solute-binding protein GSU80_RS08645 ENOG4105CXZ ABC transporter, permease GSU80_RS08650 ENOG4108VGW abc transporter atp-binding protein GSU80_RS08655 ENOG4107RM6 sulfurtransferase GSU80_RS08660 ENOG4108T9J Cdp-alcohol phosphatidyltransferase GSU80_RS08665 ENOG4105M6F mutator MutT protein GSU80_RS08670 ENOG4105MTM Protein of unknown function (DUF1496) GSU80_RS08675 ENOG4105D82 Glutamate dehydrogenase GSU80_RS08680 ENOG41065FB inner membrane protein ynji GSU80_RS08685 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) GSU80_RS08695 ENOG41069NU Nitroreductase GSU80_RS08700 ENOG4105D07 Signal peptide peptidase, SppA GSU80_RS08705 ENOG4105HDK L-asparaginase GSU80_RS08710 ENOG4108RWI nicotinamidase GSU80_RS08715 ENOG4108KUU Inner membrane metabolite transport protein ydjE GSU80_RS08720 ENOG4105E98 transcriptional regulator DeoR family GSU80_RS08725 ENOG4105CPC Aldo Keto reductase GSU80_RS08730 ENOG4107UH8 sugar kinase GSU80_RS08735 ENOG4105D2N Aldolase GSU80_RS08740 ENOG4105CPQ Dehydrogenase GSU80_RS08745 ENOG4107TE1 transport protein GSU80_RS08750 ENOG4105CPQ Dehydrogenase GSU80_RS08755 ENOG4105VUT cytoplasmic protein GSU80_RS08765 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase GSU80_RS08770 ENOG4105DSB aldose 1-epimerase GSU80_RS08775 ENOG4105CV8 reductase GSU80_RS08780 ENOG4105GNX MltA-interacting MipA family protein GSU80_RS08795 ENOG4106KTS Inner membrane protein yeaI GSU80_RS08800 ENOG4108KHP Diguanylate cyclase GSU80_RS08805 ENOG4108KXH Ybak prolyl-tRNA synthetase associated GSU80_RS08820 ENOG4105R1U AraC Family Transcriptional Regulator GSU80_RS08825 ENOG4105DJ2 Major Facilitator Superfamily GSU80_RS08830 ENOG4105K78 MarR family Transcriptional regulator GSU80_RS08835 ENOG4105UCG Domain of unknown function (DUF333) GSU80_RS08840 ENOG410620I Diguanylate cyclase GSU80_RS08845 ENOG4106G4W GSU80_RS08855 ENOG4105Y3U Transglycosylase-associated protein GSU80_RS08860 ENOG4105YP6 Domain of unknown function (DUF1869) GSU80_RS08870 ENOG4108SER Transposase GSU80_RS08875 ENOG4108YS1 cytoplasmic protein GSU80_RS08885 ENOG4105EJC lysr family transcriptional regulator GSU80_RS08890 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) GSU80_RS08895 ENOG4105C94 Transporter GSU80_RS08900 ENOG4105DVW rieske (2Fe-2S) GSU80_RS08905 ENOG4105E3J oxidoreductase GSU80_RS08910 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) GSU80_RS08915 ENOG4105CEY Amp-dependent synthetase and ligase GSU80_RS08920 ENOG4105Y4Z Outer Membrane Lipoprotein GSU80_RS08925 ENOG41072GX Peptidase M22 Glycoprotease GSU80_RS08930 ENOG4105DVT helicase GSU80_RS08935 ENOG4105M4H endoribonuclease L-psp GSU80_RS08940 ENOG4105V2F Uncharacterized protein yoac GSU80_RS08950 ENOG4105CRQ synthase (Component I) GSU80_RS08960 ENOG4105EJQ L-serine dehydratase GSU80_RS08965 ENOG4107XTP (EAL) domain protein GSU80_RS08970 ENOG4105EE5 Membrane protein terC GSU80_RS08975 ENOG4108EQA pts system GSU80_RS08980 ENOG4105ETZ PTS System GSU80_RS08985 ENOG4105F3R pts system mannose fructose sorbose family iid GSU80_RS09000 ENOG4105DHI Methyltransferase GSU80_RS09005 ENOG4105VEQ Cold shock protein GSU80_RS09010 ENOG410610J Protein of unknown function (DUF2627) GSU80_RS09015 ENOG4105Q3Y exported protein GSU80_RS09025 ENOG4105TIK GSU80_RS09030 ENOG4105J4Q Transcriptional regulator GSU80_RS09035 ENOG4105C0R drug resistance transporter emrb qaca subfamily GSU80_RS09045 ENOG4105CN1 protease GSU80_RS09055 ENOG4108ZGC gaf domain protein GSU80_RS09060 ENOG4105H2K paraquat-inducible protein a GSU80_RS09065 ENOG4105DY2 Paraquat-inducible protein b GSU80_RS09075 ENOG4105WT8 Protein of unknown function (DUF1480) GSU80_RS09080 ENOG4105UVW uncharacterized protein yebW GSU80_RS09085 ENOG4108R1E Serine threonine protein phosphatase 1 GSU80_RS09090 ENOG4105NKT exported protein GSU80_RS09095 ENOG4108PNC copper resistance GSU80_RS09100 ENOG4105FXM Copper resistance protein GSU80_RS09105 ENOG4105MPK DNA polymerase III subunit theta GSU80_RS09110 ENOG4108YGA nitrilase cyanide hydratase and apolipoprotein n-acyltransferase GSU80_RS09115 ENOG4105UMD exodeoxyribonuclease X GSU80_RS09120 ENOG4105CUG Oligopeptidase b GSU80_RS09125 ENOG4108Q2J Inner membrane protein YebE GSU80_RS09130 ENOG4105RSZ secreted protein GSU80_RS09135 ENOG4105X2V dna damage-inducible protein GSU80_RS09145 ENOG4108UHU Aldolase GSU80_RS09150 ENOG4105C01 Dihydroxy-acid dehydratase GSU80_RS09155 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase GSU80_RS09160 ENOG4106KNT transcriptional regulator GSU80_RS09165 ENOG4105CA9 Pyruvate kinase GSU80_RS09170 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase GSU80_RS09175 ENOG4105DR5 peptidase GSU80_RS09180 ENOG4105NXV High-affinity zinc uptake system protein GSU80_RS09185 ENOG4105FDK ABC transporter GSU80_RS09190 ENOG4105FAV ABC, transporter GSU80_RS09210 ENOG4107S01 Repressor protein MetJ GSU80_RS09220 ENOG4105CDY transcriptional regulatory protein GSU80_RS09225 ENOG4108TIT dATP pyrophosphohydrolase GSU80_RS09235 ENOG4105D3W isochorismatase GSU80_RS09240 ENOG41081XQ Conserved Protein GSU80_RS09245 ENOG4105WJG Glutathione GSU80_RS09260 ENOG4107QY8 reductase GSU80_RS09265 ENOG4105CUW cytochrome C-TYPE protein GSU80_RS09275 ENOG4106ZCM YecM protein GSU80_RS09290 ENOG4105W13 flagellar protein GSU80_RS09295 ENOG4105D7B Flagellar biosynthesis protein flha GSU80_RS09300 ENOG4105D00 flagellar biosynthetic protein flhB GSU80_RS09305 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) GSU80_RS09310 ENOG4108VYJ response regulator receiver protein GSU80_RS09315 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) GSU80_RS09320 ENOG4105BZU Histidine kinase GSU80_RS09325 ENOG4105C8Q Methyl-accepting chemotaxis GSU80_RS09330 ENOG4105C8Q Methyl-accepting chemotaxis GSU80_RS09335 ENOG4108V3W Chemotaxis protein, CheW GSU80_RS09340 ENOG4105CBS Chea signal transduction histidine kinase GSU80_RS09345 ENOG4105ER2 Ompa motb domain protein GSU80_RS09350 ENOG4107RD7 Flagellar Motor Protein, MotA GSU80_RS09355 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region GSU80_RS09365 ENOG4108VA4 Universal stress protein GSU80_RS09375 ENOG4108K4C ec 3.1.3.12 GSU80_RS09380 ENOG4105CNN ABC, transporter GSU80_RS09385 ENOG4105C2J ABC transporter GSU80_RS09390 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator GSU80_RS09395 ENOG4108UEC Ferritin-like protein GSU80_RS09400 ENOG4105N4N Protein of unknown function (DUF2766) GSU80_RS09410 ENOG4105P23 (LipO)protein GSU80_RS09415 ENOG41090A1 ferritin GSU80_RS09420 ENOG4105VVZ metal-binding protein GSU80_RS09425 ENOG4105E0U tyrosine-specific transport protein GSU80_RS09430 ENOG4106RHG Yeca family GSU80_RS09450 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase GSU80_RS09455 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) GSU80_RS09460 ENOG4105WH1 Two component transcriptional regulator luxr family GSU80_RS09475 ENOG4107ZY3 Histidine kinase GSU80_RS09480 ENOG4105CK6 Two component transcriptional regulator (Winged helix family GSU80_RS09485 ENOG4105VT2 5-hydroxyisourate hydrolase GSU80_RS09500 ENOG4108MEK Metal-binding protein YodA GSU80_RS09505 ENOG4108VKM cytochrome b561 GSU80_RS09525 ENOG4105TNG K13735 adhesin invasin GSU80_RS09535 ENOG4105CSH Transporter GSU80_RS09540 ENOG4105FYV Amp nucleosidase GSU80_RS09545 ENOG4105CDY transcriptional regulatory protein GSU80_RS09555 ENOG4105UQX Mate efflux family protein GSU80_RS09565 ENOG4107R11 Transcriptional regulator GSU80_RS09570 ENOG4106P55 Transcriptional regulator GSU80_RS09580 ENOG4108PXI ErfK YbiS YcfS YnhG GSU80_RS09595 ENOG4108YZT Adenosylcobinamide kinase GSU80_RS09640 ENOG4105DR8 Membrane GSU80_RS09645 ENOG4108S5C Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell (By similarity) GSU80_RS09650 ENOG4105DZ1 carboxypeptidase GSU80_RS09655 ENOG4105CJB Exodeoxyribonuclease I GSU80_RS09665 ENOG4105CUC YeeE YedE family protein GSU80_RS09670 ENOG4105CUB amino acid GSU80_RS09680 ENOG4105EQ1 Transcriptional regulator GSU80_RS09685 ENOG4108535 NAD dependent epimerase/dehydratase family GSU80_RS09700 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) GSU80_RS09710 ENOG4105ECC imidazole-glycerol-phosphate dehydratase GSU80_RS09715 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) GSU80_RS09730 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase GSU80_RS09735 ENOG4108KPN Confers a modal distribution of chain length on the O- antigen component of lipopolysaccharide (LPS). Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules, with a modal value of 13 (in strain O111 M92) and of 17 (in strain K12) GSU80_RS09740 ENOG4105C6Y Udp-glucose 6-dehydrogenase GSU80_RS09745 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) GSU80_RS09750 ENOG4107QKV phosphomannomutase GSU80_RS09755 ENOG4105CJT Mannose-1-phosphate guanylyltransferase GSU80_RS09765 ENOG4108RYC glycosyltransferase GSU80_RS09790 ENOG4108UT6 Transferase hexapeptide repeat containing protein GSU80_RS09805 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase GSU80_RS09810 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) GSU80_RS09815 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase GSU80_RS09820 ENOG4105C1B dTDP-glucose 4-6-dehydratase GSU80_RS09825 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase GSU80_RS09830 ENOG4105G1A colanic acid biosynthesis protein GSU80_RS09835 ENOG4107T8Q Glycosyl transferase (Group 1 GSU80_RS09840 ENOG4105C74 pyruvyl transferase GSU80_RS09845 ENOG4105PSV Polysaccharide Biosynthesis Protein GSU80_RS09850 ENOG4105D3Q Sugar transferase GSU80_RS09855 ENOG4107QKV phosphomannomutase GSU80_RS09860 ENOG4105CJT Mannose-1-phosphate guanylyltransferase GSU80_RS09865 ENOG4106CD9 glycosyl transferase group 1 GSU80_RS09870 ENOG4105FGF GDP-mannose mannosyl hydrolase GSU80_RS09875 ENOG4105C30 Nad-dependent epimerase dehydratase GSU80_RS09880 ENOG4105C0K Gdp-mannose 4,6-dehydratase GSU80_RS09885 ENOG4108Z90 colanic acid biosynthesis acetyltransferase wcaF GSU80_RS09890 ENOG4105ECJ Glycosyl Transferase GSU80_RS09895 ENOG4108NYJ Colanic acid GSU80_RS09900 ENOG4107RXY Glycosyl transferase GSU80_RS09905 ENOG41068PY Colanic acid biosynthesis acetyltransferase wcaB GSU80_RS09910 ENOG41090RK glycosyl transferase GSU80_RS09915 ENOG4105D75 Capsular exopolysaccharide family GSU80_RS09920 ENOG4105KJF protein tyrosine phosphatase GSU80_RS09925 ENOG4105DAY polysaccharide export protein GSU80_RS09930 ENOG4105EE5 Membrane protein terC GSU80_RS09935 ENOG4108GAE asmA family GSU80_RS09945 ENOG4105DBI uridine monophosphokinase GSU80_RS09950 ENOG4105BZU Histidine kinase GSU80_RS09955 ENOG4105D03 DNA-3-methyladenine glycosylase II GSU80_RS09960 ENOG4105R8A Heat shock protein GSU80_RS09965 ENOG4106E1W protein with protein kinase and helix-hairpin-helix DNA-binding GSU80_RS09970 ENOG4105UM3 Inherit from NOG: serine threonine phosphoprotein phosphatase GSU80_RS09975 ENOG4108M24 von Willebrand factor, type A GSU80_RS10010 ENOG4105BZS acriflavin resistance protein GSU80_RS10020 ENOG4105EB3 Histidine kinase GSU80_RS10025 ENOG4105E3W Two component transcriptional regulator (Winged helix family GSU80_RS10030 ENOG4105KWI UPF0339 protein GSU80_RS10035 ENOG4105CFP Peptidase U32 GSU80_RS10040 ENOG41076Z6 Uncharacterized protein yegR GSU80_RS10065 ENOG4107WTH Galactitol-1-phosphate dehydrogenase GSU80_RS10070 ENOG4105DT3 PTS system, galactitol-specific IIc component GSU80_RS10075 ENOG41090UW PTS System GSU80_RS10080 ENOG41082GB PTS system galactitol-specific transporter subunit IIA GSU80_RS10095 ENOG4105EIE fructose-bisphosphate aldolase GSU80_RS10100 ENOG4105EAA nucleoside GSU80_RS10105 ENOG4108KD5 ADP-ribosylation crystallin J1 GSU80_RS10110 ENOG4108TFM Kinase, PfkB family GSU80_RS10115 ENOG4105FDP GntR family transcriptional regulator GSU80_RS10120 ENOG4108UQ1 hydrolase, family 25 GSU80_RS10125 ENOG4105DWF phosphomethylpyrimidine kinase GSU80_RS10165 ENOG41067AK Protein of unknown function (DUF2574) GSU80_RS10170 ENOG4105D1F ATP-binding protein GSU80_RS10180 ENOG4108KDT Molybdate metabolism regulator GSU80_RS10185 ENOG4108KDT Molybdate metabolism regulator GSU80_RS10195 ENOG4105KKX ATPase associated with various cellular activities aaa_5 GSU80_RS10200 ENOG4105RD5 GSU80_RS10205 ENOG4105DEG Vwa containing coxe family protein GSU80_RS10210 ENOG410903U zinc ion binding GSU80_RS10215 ENOG4108YCW (LipO)protein GSU80_RS10220 ENOG4108W15 Protein of unknown function (DUF1456) GSU80_RS10225 ENOG4108NEV two component transcriptional regulator, LytTR family GSU80_RS10230 ENOG4108HRK Histidine kinase GSU80_RS10235 ENOG4108XDN Transcriptional regulator GSU80_RS10245 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component GSU80_RS10250 ENOG4108IJ8 ABC transporter GSU80_RS10255 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component GSU80_RS10260 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system GSU80_RS10265 ENOG4107QK4 glycoside hydrolase, family 3 domain protein GSU80_RS10270 ENOG4105CXG d-lactate dehydrogenase GSU80_RS10275 ENOG41061WM D-Alanyl-D-Alanine GSU80_RS10280 ENOG41069YE inner membrane protein yohC GSU80_RS10285 ENOG4105KHU inner membrane protein YohD GSU80_RS10290 ENOG4105H9W Short-chain dehydrogenase reductase Sdr GSU80_RS10295 ENOG4105ETP RND efflux system, outer membrane lipoprotein GSU80_RS10305 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) GSU80_RS10315 ENOG41067MG lrgb family GSU80_RS10325 ENOG4107GZ4 SanA protein GSU80_RS10330 ENOG4105Y9N Membrane GSU80_RS10335 ENOG4105BZ8 glutamate synthase GSU80_RS10340 ENOG4107SJI Dehydrogenase GSU80_RS10345 ENOG4108HWV )-transporter GSU80_RS10350 ENOG4105C2J ABC transporter GSU80_RS10360 ENOG41060NJ transcriptional regulator GSU80_RS10365 ENOG4105DHF Membrane GSU80_RS10375 ENOG4105C4W S-formylglutathione hydrolase GSU80_RS10380 ENOG4105D05 Receptor GSU80_RS10385 ENOG4108IQI permease GSU80_RS10390 ENOG4105DUM transcriptional regulator, lysR family GSU80_RS10395 ENOG4105HMI Membrane GSU80_RS10405 ENOG4105DD7 kinase (PfkB family GSU80_RS10410 ENOG4105D9N nucleoside GSU80_RS10420 ENOG4108Y4K DNA-binding transcriptional activator GSU80_RS10425 ENOG4105D9N nucleoside GSU80_RS10430 ENOG4105D53 Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity) GSU80_RS10435 ENOG4105DD7 kinase (PfkB family GSU80_RS10440 ENOG4105DM4 PTS System GSU80_RS10445 ENOG4105DE4 1-phosphofructokinase GSU80_RS10450 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein GSU80_RS10455 ENOG4105S8Q sugar efflux transporter GSU80_RS10460 ENOG4105KRS Proteinase inhibitor GSU80_RS10470 ENOG4105DEI Mannitol dehydrogenase GSU80_RS10475 ENOG4105CKI cobalamin synthesis protein GSU80_RS10480 ENOG41076MN Phosphoesterase, PA-phosphatase related GSU80_RS10485 ENOG4107TT5 NLP P60 protein GSU80_RS10490 ENOG4105CXC rtn protein GSU80_RS10495 ENOG4105E43 Extracellular solute-binding protein, family 5 GSU80_RS10500 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component GSU80_RS10505 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component GSU80_RS10510 ENOG4108JQ5 ABC transporter GSU80_RS10515 ENOG4105HG6 GSU80_RS10520 ENOG4105C2C drug resistance transporter, Bcr CflA GSU80_RS10525 ENOG4105I08 Pseudouridine synthase GSU80_RS10530 ENOG4105CFI type iii restriction protein res subunit GSU80_RS10550 ENOG4105E68 Sulfatase GSU80_RS10560 ENOG4108MGN ATP-binding component of a transport system GSU80_RS10565 ENOG4105WH1 Two component transcriptional regulator luxr family GSU80_RS10570 ENOG4105KWW Biogenesis protein GSU80_RS10575 ENOG4107QX9 Thiol disulfide interChange protein GSU80_RS10580 ENOG4105DA4 cytochrome c-type biogenesis protein GSU80_RS10590 ENOG4105X3C heme exporter protein GSU80_RS10595 ENOG41060IM Heme exporter protein GSU80_RS10600 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) GSU80_RS10605 ENOG4107EV4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity) GSU80_RS10610 ENOG4105CUW cytochrome C-TYPE protein GSU80_RS10615 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) GSU80_RS10620 ENOG4105GXZ Ferredoxin-type protein NapH GSU80_RS10625 ENOG4108BGM Quinol dehydrogenase periplasmic component GSU80_RS10635 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase GSU80_RS10640 ENOG4108ZNS ferredoxin-type protein NapF GSU80_RS10650 ENOG4105DWT malate dehydrogenase (quinone) GSU80_RS10655 ENOG4105IBP Cyclic peptide transporter GSU80_RS10660 ENOG4105CF1 Alkylated DNA repair protein GSU80_RS10665 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) GSU80_RS10670 ENOG4105CJ2 (LipO)protein GSU80_RS10675 ENOG4105FCK Membrane GSU80_RS10685 ENOG4105BZU Histidine kinase GSU80_RS10690 ENOG4105BZU Histidine kinase GSU80_RS10695 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family GSU80_RS10700 ENOG4107QP7 CoA-transferase subunit A GSU80_RS10705 ENOG4107QNJ CoA-transferase subunit B GSU80_RS10710 ENOG4105CRW Short chain fatty acid transporter GSU80_RS10715 ENOG4105CHU acetyl-coa acetyltransferase GSU80_RS10720 ENOG4105EDV vault protein GSU80_RS10725 ENOG41081SK signal peptide protein GSU80_RS10730 ENOG4107S52 alpha-2-macroglobulin domain protein GSU80_RS10735 ENOG4108QJJ Protein of unknown function (DUF1175) GSU80_RS10740 ENOG4107FKF Uncharacterized protein conserved in bacteria (DUF2138) GSU80_RS10745 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) GSU80_RS10750 ENOG4108HWB Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) GSU80_RS10755 ENOG4107GHC outer membrane autotransporter GSU80_RS10760 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) GSU80_RS10765 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) GSU80_RS10770 ENOG4105XPH Ferredoxin GSU80_RS10775 ENOG4105FQR PH-inducible protein involved in stress response GSU80_RS10785 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase GSU80_RS10790 ENOG4105CXY transporter GSU80_RS10795 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A GSU80_RS10805 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) GSU80_RS10810 ENOG4105DNE Transposase GSU80_RS10820 ENOG4105CSP Major Facilitator Superfamily GSU80_RS10830 ENOG4107258 Transcriptional regulator GSU80_RS10840 ENOG4108UII YfaZ family GSU80_RS10870 ENOG4105F73 Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity) GSU80_RS10875 ENOG4105SA9 Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity) GSU80_RS10885 ENOG4105U65 Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity) GSU80_RS10890 ENOG4106GZG polymyxin resistance protein B GSU80_RS10895 ENOG4105CEY Amp-dependent synthetase and ligase GSU80_RS10905 ENOG4108IPT Naphthoate synthase GSU80_RS10920 ENOG4105E4F Isochorismate synthase GSU80_RS10925 ENOG4105TNS Conserved Protein GSU80_RS10930 ENOG4107YB6 acetyltransferase, (GNAT) family GSU80_RS10940 ENOG4105Z6G Protease that can act as an efficient and specific deubiquitinating enzyme in vitro. Does not possess desumoylating and deneddylating activities. The physiological substrate is GSU80_RS10950 ENOG4105GDX Domain of unknown function (DUF1877) GSU80_RS10965 ENOG4105C8S subunit m GSU80_RS10970 ENOG4105D65 subunit l GSU80_RS10975 ENOG41080EA NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) GSU80_RS10980 ENOG4107UFS subunit j GSU80_RS10985 ENOG4105P3U NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) GSU80_RS10995 ENOG4108IEH NADH dehydrogenase subunit g GSU80_RS11000 ENOG4107QIZ NADH dehydrogenase GSU80_RS11005 ENOG4105GKE subunit e GSU80_RS11025 ENOG4107NQ8 LysR family Transcriptional regulator GSU80_RS11030 ENOG4105CHM Aminotransferase GSU80_RS11040 ENOG4107QWE )-transporter GSU80_RS11045 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 GSU80_RS11060 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) GSU80_RS11065 ENOG4105C6K Malic enzyme GSU80_RS11070 ENOG4105CSX c4-dicarboxylate anaerobic carrier GSU80_RS11075 ENOG4105PTV Nudix Hydrolase GSU80_RS11080 ENOG4108RE9 Phosphodiesterase GSU80_RS11085 ENOG4108SHQ Glutathione S-transferase GSU80_RS11090 ENOG4105CYM Glutathione S-transferase GSU80_RS11095 ENOG4105KKP D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase GSU80_RS11100 ENOG4105ECP epimerase GSU80_RS11105 ENOG4105DNE Transposase GSU80_RS11110 ENOG4108JEH abc transporter atp-binding protein GSU80_RS11115 ENOG4106YG3 ABC transporter GSU80_RS11120 ENOG4105DSP amino acid AbC transporter GSU80_RS11125 ENOG4105E89 ABC transporter GSU80_RS11130 ENOG4105E89 ABC transporter GSU80_RS11135 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase GSU80_RS11140 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase GSU80_RS11145 ENOG4105E96 Colicin v production protein GSU80_RS11150 ENOG4108S3P Sporulation domain protein GSU80_RS11155 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase GSU80_RS11165 ENOG4105DQR SNARE associated Golgi GSU80_RS11175 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) GSU80_RS11180 ENOG4105CJ0 Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity) GSU80_RS11185 ENOG4106WZ1 flagella biosynthesis regulator GSU80_RS11190 ENOG4105F9N Major Facilitator Superfamily GSU80_RS11195 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) GSU80_RS11200 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) GSU80_RS11205 ENOG4105MH2 YfcL protein GSU80_RS11210 ENOG4108BPE -transporting atpase GSU80_RS11215 ENOG4105EJ9 Membrane GSU80_RS11225 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase GSU80_RS11235 ENOG4108DG9 Smr protein MutS2 GSU80_RS11245 ENOG4105US4 fimbrial-like protein yfcP GSU80_RS11250 ENOG4105UGQ Fimbrial GSU80_RS11255 ENOG4105NEV Fimbrial GSU80_RS11260 ENOG4108FZ9 Chaperone GSU80_RS11265 ENOG4106PG1 outer membrane usher protein GSU80_RS11275 ENOG4108BY2 phosphohistidine phosphatase GSU80_RS11290 ENOG4105KZW UPF0381 protein GSU80_RS11295 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation GSU80_RS11315 ENOG410903C (LipO)protein GSU80_RS11320 ENOG4105S64 Formate nitrite transporter GSU80_RS11330 ENOG4105W8I Transcriptional regulator GSU80_RS11335 ENOG4105C6Z Gluconate GSU80_RS11345 ENOG4105C0R drug resistance transporter emrb qaca subfamily GSU80_RS11350 ENOG4105CW7 secretion protein, HlyD family GSU80_RS11355 ENOG4108WQH regulatoR GSU80_RS11360 ENOG4105BZU Histidine kinase GSU80_RS11365 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F GSU80_RS11370 ENOG4108N2Y auxin Efflux GSU80_RS11375 ENOG4105CFN oxalyl-CoA decarboxylase GSU80_RS11385 ENOG4108V08 YfdX protein GSU80_RS11395 ENOG4105W9M Membrane GSU80_RS11400 ENOG4105D1S lipid A biosynthesis GSU80_RS11410 ENOG4105CHM Aminotransferase GSU80_RS11415 ENOG4108HRK Histidine kinase GSU80_RS11420 ENOG4105DY9 regulatoR GSU80_RS11425 ENOG4108CIP transcriptional regulator GSU80_RS11430 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) GSU80_RS11435 ENOG4105CN9 Peptidase m42 family protein GSU80_RS11440 ENOG4105DC7 peptidase M24 GSU80_RS11445 ENOG410863U PTS System GSU80_RS11450 ENOG4105R6B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) GSU80_RS11460 ENOG4105VCT ion-transport protein YfeO GSU80_RS11465 ENOG4109076 Conserved Protein GSU80_RS11475 ENOG4105D9N nucleoside GSU80_RS11480 ENOG4108KMM Diguanylate cyclase GSU80_RS11495 ENOG4105HZG regulatoR GSU80_RS11500 ENOG4105GXM Putative transcription regulator (DUF1323) GSU80_RS11535 ENOG4108M0I Transcriptional regulator GSU80_RS11540 ENOG4105DHU Bile acid GSU80_RS11545 ENOG4105VRT cytoplasmic protein GSU80_RS11565 ENOG4105C6T cysteine synthase GSU80_RS11570 ENOG4105KZ7 phosphocarrier protein hpr GSU80_RS11575 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) GSU80_RS11580 ENOG4105C5Y PTS System GSU80_RS11590 ENOG4105M0Y GSU80_RS11595 ENOG4105WEC Molybdate metabolism regulator GSU80_RS11600 ENOG4105C6T cysteine synthase GSU80_RS11605 ENOG4108IJ6 ABC transporter GSU80_RS11610 ENOG4105ECW sulfate abc transporter GSU80_RS11615 ENOG4108I5D sulfate abc transporter GSU80_RS11620 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein GSU80_RS11625 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr GSU80_RS11630 ENOG4108PSC Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity) GSU80_RS11640 ENOG4105C5Y PTS System GSU80_RS11645 ENOG4105EZR dyp-type peroxidase family protein GSU80_RS11650 ENOG4105E7K (LipO)protein GSU80_RS11655 ENOG4105QZU Inner membrane protein YfeZ GSU80_RS11660 ENOG4108R6G acetyltransferase GSU80_RS11665 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase GSU80_RS11675 ENOG4108K3Z AraC family transcriptional regulator GSU80_RS11680 ENOG4108X49 Ethanolamine utilization protein EutK GSU80_RS11685 ENOG4106D67 ethanolamine utilization protein GSU80_RS11695 ENOG4105CPD ethanolamine ammonia-lyase GSU80_RS11700 ENOG4105DYY Reactivating factor for ethanolamine ammonia lyase GSU80_RS11705 ENOG4105ENY Ethanolamine utilization protein eutH GSU80_RS11710 ENOG4105C0A alcohol dehydrogenase GSU80_RS11715 ENOG4107RWI ethanolamine utilization protein eutJ GSU80_RS11720 ENOG4108EKI Dehydrogenase GSU80_RS11725 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml GSU80_RS11730 ENOG4105KNY Microcompartments protein GSU80_RS11735 ENOG4107WUY phosphate acetyltransferase GSU80_RS11740 ENOG4108PFF ethanolamine utilization cobalamin adenosyltransferase GSU80_RS11745 ENOG4105NDK ethanolamine utilization protein GSU80_RS11750 ENOG4106S4J ethanolamine utilization protein EutP GSU80_RS11755 ENOG4108VJN May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place GSU80_RS11760 ENOG4105C6K Malic enzyme GSU80_RS11765 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) GSU80_RS11770 ENOG4105CV1 Transketolase (EC 2.2.1.1) GSU80_RS11775 ENOG4108PVD exported protein GSU80_RS11780 ENOG4107VIJ nudix hydrolase GSU80_RS11785 ENOG4105BZ8 glutamate synthase GSU80_RS11790 ENOG4105BZU Histidine kinase GSU80_RS11795 ENOG4105BZS acriflavin resistance protein GSU80_RS11805 ENOG4105KUZ arsenate reductase GSU80_RS11820 ENOG4106KED esterase YpfH GSU80_RS11825 ENOG4105E0I Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity) GSU80_RS11830 ENOG4105CGZ zinc metallopeptidase GSU80_RS11840 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) GSU80_RS11850 ENOG4105RH4 Glycine cleavage system transcriptional repressor GSU80_RS11855 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen GSU80_RS11860 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) GSU80_RS11865 ENOG4108JPZ Monovalent cation H antiporter subunit D GSU80_RS11875 ENOG4105D65 subunit l GSU80_RS11880 ENOG4105D65 subunit l GSU80_RS11885 ENOG4107WQX hydrogenase 4 membrane subunit GSU80_RS11890 ENOG4108JPZ Monovalent cation H antiporter subunit D GSU80_RS11895 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) GSU80_RS11905 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit GSU80_RS11910 ENOG4105I6X formate hydrogenlyase maturation GSU80_RS11915 ENOG4108JUA Transcriptional regulator GSU80_RS11920 ENOG4105TMB Formate nitrite transporter GSU80_RS11925 ENOG4105C02 permease GSU80_RS11930 ENOG4105ERG peptidase m48, ste24p GSU80_RS11935 ENOG4105K89 arsenate reductase GSU80_RS11945 ENOG4105C2W permease GSU80_RS11960 ENOG4108V3E phosphoribosylglycinamide formyltransferase GSU80_RS11965 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) GSU80_RS11970 ENOG4105C9X ppx gppa phosphatase GSU80_RS11975 ENOG4105BZU Histidine kinase GSU80_RS11980 ENOG41062G3 Protein of unknown function (DUF2633) GSU80_RS11985 ENOG4108ZMA Outer membrane lipoprotein GSU80_RS11990 ENOG41066DY Membrane GSU80_RS12000 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) GSU80_RS12010 ENOG4105VPD cellular component movement GSU80_RS12025 ENOG4105N21 Membrane GSU80_RS12055 ENOG4108JQB penicillin-binding protein 1C GSU80_RS12060 ENOG4105DN3 alpha-2-macroglobulin domain protein GSU80_RS12065 ENOG4105KHC sulfurtransferase GSU80_RS12075 ENOG4105YYA enhanced serine sensitivity protein SseB GSU80_RS12085 ENOG4105WVQ Fe-S assembly protein IscX GSU80_RS12090 ENOG4108ZIT Ferredoxin, 2FE-2S GSU80_RS12110 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins GSU80_RS12135 ENOG4107XM9 (LipO)protein GSU80_RS12140 ENOG4108MN2 Stationary phase inducible protein CsiE GSU80_RS12145 ENOG4105D8G Major Facilitator superfamily GSU80_RS12150 ENOG4108W5M transcriptional regulator GSU80_RS12155 ENOG4105FUY alpha subunit GSU80_RS12180 ENOG4108SB3 DoxX Family GSU80_RS12185 ENOG4108ZKT aldose 1-epimerase GSU80_RS12190 ENOG4105CPQ Dehydrogenase GSU80_RS12195 ENOG4105CNN ABC, transporter GSU80_RS12200 ENOG4108F37 ATP-binding component of a transport system GSU80_RS12205 ENOG4105FCA ABC transporter periplasmic-binding protein YphF GSU80_RS12210 ENOG4107HQ7 repeat protein GSU80_RS12215 ENOG4108NZE NAGC-like transcriptional regulator GSU80_RS12225 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) GSU80_RS12230 ENOG4108YZA Nitrogen regulatory protein pii GSU80_RS12235 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family GSU80_RS12240 ENOG4108SKK alpha helix protein GSU80_RS12245 ENOG4107WP9 Histidine kinase GSU80_RS12265 ENOG4108Z6B deaminase GSU80_RS12270 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB GSU80_RS12275 ENOG4106G6Q Transcriptional regulator GSU80_RS12280 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding GSU80_RS12295 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) GSU80_RS12315 ENOG4105C3F Signal peptidase i GSU80_RS12325 ENOG4105WMJ Positive regulator of sigma E, RseC MucC GSU80_RS12330 ENOG4105VQK sigma E regulatory protein, MucB RseB GSU80_RS12335 ENOG41069PW sigma-e factor negative regulatory protein GSU80_RS12340 ENOG4105EMN RNA polymerase sigma factor GSU80_RS12350 ENOG4108IYU L-aspartate oxidase GSU80_RS12355 ENOG4107S47 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity) GSU80_RS12360 ENOG4105C1J atp-dependent rna helicase GSU80_RS12365 ENOG41090KR LysR family transcriptional Regulator GSU80_RS12380 ENOG4105D5S Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity) GSU80_RS12385 ENOG4105EIB trna rrna methyltransferase GSU80_RS12390 ENOG4105K63 Thioredoxin GSU80_RS12395 ENOG4106IUH DTW domain containing protein GSU80_RS12400 ENOG4105CD5 CoA-binding domain protein GSU80_RS12405 ENOG4105JIM Phosphatidylserine synthase GSU80_RS12410 ENOG4105T42 (LipO)protein GSU80_RS12415 ENOG4105CSH Transporter GSU80_RS12440 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit GSU80_RS12445 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase GSU80_RS12450 ENOG4105C34 Pseudouridine synthase GSU80_RS12455 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane GSU80_RS12460 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA GSU80_RS12470 ENOG4105CQC Prephenate dehydratase GSU80_RS12475 ENOG4105EHE chorismate mutase- prephenate dehydrogenase GSU80_RS12480 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) GSU80_RS12485 ENOG4105QP9 Protein of unknown function (DUF2799) GSU80_RS12490 ENOG4108WS1 GSU80_RS12495 ENOG4108KHX Diguanylate cyclase GSU80_RS12500 ENOG41090EK ompa motb domain protein GSU80_RS12525 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY GSU80_RS12530 ENOG4106KVJ cytochrome C assembly protein GSU80_RS12535 ENOG4108JU6 CBS domain protein GSU80_RS12550 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) GSU80_RS12555 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) GSU80_RS12560 ENOG4105VDB UPF0125 protein GSU80_RS12565 ENOG4108Z1B Cyclase dehydrase GSU80_RS12580 ENOG4105DFP Integrase GSU80_RS12590 ENOG4105FA0 parb-like partition protein GSU80_RS12610 ENOG4105D5U fad dependent oxidoreductase GSU80_RS12615 ENOG4105C26 Dehydrogenase GSU80_RS12620 ENOG4108JPW Aminotransferase GSU80_RS12625 ENOG4105C85 amino acid GSU80_RS12630 ENOG4108PVQ transcriptional regulator GSU80_RS12635 ENOG4109066 lysm domain bon superfamily protein GSU80_RS12640 ENOG4105VPI YqaE family transport protein GSU80_RS12645 ENOG41080HT Transcriptional regulator, arsr family GSU80_RS12650 ENOG4108V62 Rhodanese domain protein GSU80_RS12655 ENOG4108X73 DNA- binding protein GSU80_RS12660 ENOG4108RNS Exports L-alanine (By similarity) GSU80_RS12665 ENOG4108WMJ Protein of unknown function (DUF2002) GSU80_RS12670 ENOG4108ZQZ Bacterial protein of unknown function (DUF883) GSU80_RS12675 ENOG4105WAZ (Glutaredoxin-like protein) NrdH GSU80_RS12680 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) GSU80_RS12685 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) GSU80_RS12690 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) GSU80_RS12695 ENOG4108IJ7 Glycine betaine GSU80_RS12700 ENOG4108HQS Glycine betaine GSU80_RS12705 ENOG4105GIJ Glycine betaine GSU80_RS12715 ENOG4108UMN azlc family GSU80_RS12720 ENOG4105ZED uncharacterized protein ygaH GSU80_RS12725 ENOG4105NTK Transcriptional repressor Mpra GSU80_RS12730 ENOG4105CW7 secretion protein, HlyD family GSU80_RS12735 ENOG4105C0R drug resistance transporter emrb qaca subfamily GSU80_RS12750 ENOG4105W39 Membrane GSU80_RS12755 ENOG4107VXZ Hydrolase GSU80_RS12785 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) GSU80_RS12790 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) GSU80_RS12805 ENOG4107TH8 cina domain protein GSU80_RS12810 ENOG4105CVE Lytic murein transglycosylase GSU80_RS12815 ENOG410787A Pts system, glucitol sorbitol-specific GSU80_RS12820 ENOG4105DZY Pts system, glucitol sorbitol-specific GSU80_RS12825 ENOG4105VI0 Pts system, glucitol sorbitol-specific GSU80_RS12830 ENOG4107QMF Sorbitol-6-phosphate dehydrogenase GSU80_RS12835 ENOG4105J92 DNA-binding transcriptional activator GutM GSU80_RS12840 ENOG410804X Transcriptional regulator GSU80_RS12845 ENOG4105C2X Arabinose 5-phosphate isomerase GSU80_RS12865 ENOG4105C8H hydrogenase maturation protein Hypf GSU80_RS12870 ENOG4108RC0 Electron transport protein GSU80_RS12875 ENOG4105DDV Transcriptional regulator (LacI family GSU80_RS12880 ENOG4105C5Y PTS System GSU80_RS12885 ENOG4105CS2 ec 3.2.1.21 GSU80_RS12890 ENOG4108MG9 hydrogenase 3 maturation protease GSU80_RS12895 ENOG4105I6X formate hydrogenlyase maturation GSU80_RS12900 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit GSU80_RS12905 ENOG4108RG7 formate hydrogenlyase complex iron-sulfur subunit GSU80_RS12910 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) GSU80_RS12915 ENOG4107TDF Formate hydrogenlyase subunit 4 GSU80_RS12920 ENOG4107R30 NADH dehydrogenase GSU80_RS12925 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) GSU80_RS12930 ENOG4108VRC Formate hydrogenlyase regulatory protein hycA GSU80_RS12940 ENOG410816D Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) GSU80_RS12945 ENOG4107RSS Hydrogenase accessory protein HypB GSU80_RS12950 ENOG41083WG hydrogenase assembly chaperone GSU80_RS12955 ENOG4105CQS hydrogenase expression formation protein HypD GSU80_RS12960 ENOG4105C45 hydrogenase expression formation protein (HypE) GSU80_RS12965 ENOG4108JUA Transcriptional regulator GSU80_RS12970 ENOG4105VXR cytoplasmic protein GSU80_RS12980 ENOG4105MEW serine threonine protein phosphatase GSU80_RS12985 ENOG4105MVE transcriptional regulator GSU80_RS12990 ENOG4105ZXK Dehydrogenase GSU80_RS12995 ENOG4105G63 Type III effector Hrp-dependent GSU80_RS13000 ENOG4105FB2 class II Aldolase GSU80_RS13005 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) GSU80_RS13010 ENOG4105C6Z Gluconate GSU80_RS13015 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) GSU80_RS13020 ENOG4108K5P (LipO)protein GSU80_RS13055 ENOG4105N0Z inner membrane protein ygbE GSU80_RS13065 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) GSU80_RS13075 ENOG4108MXK alkaline phosphatase isozyme conversion GSU80_RS13080 ENOG4108SER Transposase GSU80_RS13085 ENOG4107635 Hok Gef family protein GSU80_RS13095 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) GSU80_RS13105 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase GSU80_RS13110 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase GSU80_RS13115 ENOG4105WQV ferredoxin-like protein GSU80_RS13120 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator GSU80_RS13125 ENOG4105YBM electron transfer flavoprotein subunit ygcQ GSU80_RS13130 ENOG4106IKH Electron transfer flavoprotein GSU80_RS13135 ENOG4105C54 Major Facilitator superfamily GSU80_RS13140 ENOG4107R3A FAD linked oxidase domain protein GSU80_RS13145 ENOG4105CHR reductase GSU80_RS13150 ENOG4108ITV Inner membrane protein yqcE GSU80_RS13155 ENOG4108CWB sugar kinase ygcE GSU80_RS13160 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) GSU80_RS13170 ENOG4105HA9 of methanol dehydrogenase type GSU80_RS13185 ENOG4105DXN mazG family GSU80_RS13190 ENOG4105MZG transcriptional modulator of maze toxin, mazf GSU80_RS13195 ENOG4106A2Z transcriptional regulator antitoxin, MazE GSU80_RS13200 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) GSU80_RS13205 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) GSU80_RS13210 ENOG4105BZU Histidine kinase GSU80_RS13215 ENOG4105EQX glucarate dehydratase GSU80_RS13220 ENOG4105EQX glucarate dehydratase GSU80_RS13225 ENOG4105DJB Major Facilitator Superfamily GSU80_RS13230 ENOG4105QDK Flavodoxin GSU80_RS13235 ENOG4105DR9 pseudouridine synthase GSU80_RS13240 ENOG4105WP7 tRNA pseudouridine synthase C GSU80_RS13255 ENOG4105EWT decarboxylase family GSU80_RS13260 ENOG4105C44 Serine transporter GSU80_RS13265 ENOG4105EJQ L-serine dehydratase GSU80_RS13275 ENOG4105C0A alcohol dehydrogenase GSU80_RS13300 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) GSU80_RS13310 ENOG4105CNN ABC, transporter GSU80_RS13315 ENOG4105C2J ABC transporter GSU80_RS13325 ENOG4105CMG Carbohydrate kinase GSU80_RS13335 ENOG4107EDW L-fucose operon activator GSU80_RS13345 ENOG4105M08 Membrane GSU80_RS13350 ENOG4105ETT transcriptional Regulator, LysR family GSU80_RS13355 ENOG4105M5B (LipO)protein GSU80_RS13360 ENOG4105C9B Cysteine desulfurase GSU80_RS13365 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) GSU80_RS13370 ENOG4105CUZ uba thif-type nad fad binding protein GSU80_RS13375 ENOG4105CA3 membrane-bound lytic murein transglycosylase GSU80_RS13395 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase GSU80_RS13400 ENOG4107QZM n-acetylglutamate synthase GSU80_RS13405 ENOG4107QYX exodeoxyribonuclease v alpha GSU80_RS13410 ENOG4107QKA exodeoxyribonuclease V beta GSU80_RS13415 ENOG4107QXK peptidase GSU80_RS13420 ENOG4105DSY exodeoxyribonuclease V, gamma GSU80_RS13425 ENOG4105RVB Prepilin peptidase dependent protein c GSU80_RS13430 ENOG4105SEN Protein of unknown function (DUF2509) GSU80_RS13435 ENOG4105JCS prepilin peptidase dependent protein GSU80_RS13440 ENOG4105IPU prepilin peptidase dependent protein A GSU80_RS13455 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase GSU80_RS13470 ENOG4105EE5 Membrane protein terC GSU80_RS13475 ENOG4105SUV lipoprotein YgdR GSU80_RS13480 ENOG4105CPC Aldo Keto reductase GSU80_RS13495 ENOG41060NJ transcriptional regulator GSU80_RS13500 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) GSU80_RS13505 ENOG4105RQF LysR family Transcriptional regulator GSU80_RS13515 ENOG4107QNK )-transporter GSU80_RS13540 ENOG4105CHU acetyl-coa acetyltransferase GSU80_RS13545 ENOG4108MHD transport protein GSU80_RS13550 ENOG4105ISV protein with bipartite regulator domain GSU80_RS13570 ENOG4108K5P (LipO)protein GSU80_RS13575 ENOG4105C7W Xanthine dehydrogenase GSU80_RS13580 ENOG4108HR6 Dehydrogenase GSU80_RS13585 ENOG4108UTP (2Fe-2S)-binding domain protein GSU80_RS13590 ENOG4108JUB Transcriptional regulator GSU80_RS13595 ENOG4105IW6 Carbamoyltransferase GSU80_RS13600 ENOG4107RCH Diaminopropionate ammonia-lyase GSU80_RS13605 ENOG4107S4Y M20 DapE family protein YgeY GSU80_RS13615 ENOG4105C5B carbamate kinase GSU80_RS13620 ENOG4107P0T Selenium-dependent molybdenum hydroxylase system protein, YqeB family GSU80_RS13625 ENOG4105MJ6 selenium-dependent hydroxylase accessory protein YqeC GSU80_RS13630 ENOG4105MFX 4-diphosphocytidyl-2c-methyl-d-erythritol synthase GSU80_RS13635 ENOG4105BZ8 glutamate synthase GSU80_RS13640 ENOG4107UUR Chlorohydrolase aminohydrolase GSU80_RS13645 ENOG410873Y FAD binding domain in molybdopterin dehydrogenase GSU80_RS13650 ENOG4105C7W Xanthine dehydrogenase GSU80_RS13655 ENOG4105C2W permease GSU80_RS13660 ENOG4107QUY Guanine deaminase GSU80_RS13665 ENOG4105C7N Xanthine uracil vitamin C permease GSU80_RS13670 ENOG4108R8B oxidoreductase Fe-S subunit GSU80_RS13675 ENOG4105BZ8 glutamate synthase GSU80_RS13680 ENOG4105C2W permease GSU80_RS13700 ENOG4105CRK lysyL-tRNA synthetase GSU80_RS13710 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) GSU80_RS13715 ENOG4105T95 Thiol disulfide interChange protein GSU80_RS13720 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) GSU80_RS13725 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) GSU80_RS13730 ENOG4108YDB Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB GSU80_RS13735 ENOG4105Y75 tpr repeat protein GSU80_RS13745 ENOG4108UT2 hemolysin iii GSU80_RS13755 ENOG4105CS2 ec 3.2.1.21 GSU80_RS13760 ENOG4105CYX Short-chain dehydrogenase reductase Sdr GSU80_RS13785 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family GSU80_RS13790 ENOG4105D0A hydroxylase GSU80_RS13795 ENOG4107RAQ aminopeptidase GSU80_RS13815 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase GSU80_RS13825 ENOG4108JQ1 Dehydrogenase GSU80_RS13845 ENOG4105D5P Methylmalonyl-coA mutase GSU80_RS13850 ENOG4105DJT lAO AO transport system ATPase GSU80_RS13855 ENOG4108M7F enoyl-CoA hydratase isomerase GSU80_RS13860 ENOG4105CYC Transferase GSU80_RS13865 ENOG4105DEQ transcriptional regulator GSU80_RS13870 ENOG4105MPN Membrane GSU80_RS13875 ENOG4108ZUB Lysine exporter protein (Lyse ygga) GSU80_RS13880 ENOG4105D64 Mechanosensitive ion channel GSU80_RS13885 ENOG4105D2N Aldolase GSU80_RS13900 ENOG4107Z1W Fructose transport system kinase GSU80_RS13905 ENOG4108R4K DNA-binding, transcriptional regulator GSU80_RS13910 ENOG4108Q8A Fructose-1,6-bisphosphatase GSU80_RS13915 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein GSU80_RS13920 ENOG4105CTS PTS system mannitol-specific GSU80_RS13925 ENOG4108X7Y Mannitol-specific cryptic phosphotransferase enzyme iia GSU80_RS13930 ENOG4105CV1 Transketolase (EC 2.2.1.1) GSU80_RS13935 ENOG4108K0D peptidase, M48 GSU80_RS13945 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) GSU80_RS13965 ENOG4107QNK )-transporter GSU80_RS13975 ENOG4105RWS endonuclease I GSU80_RS13980 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) GSU80_RS13985 ENOG4105D7Z glutathione synthase GSU80_RS14000 ENOG4105CZX twitching motility protein GSU80_RS14005 ENOG4105DFA alanine racemase domain protein GSU80_RS14010 ENOG4108VIA integral membrane protein GSU80_RS14020 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) GSU80_RS14025 ENOG4105CSA Coproporphyrinogen iii oxidase GSU80_RS14030 ENOG4106MH3 alpha helix chain GSU80_RS14035 ENOG4105HDK L-asparaginase GSU80_RS14040 ENOG4105K33 Periplasmic Protein GSU80_RS14045 ENOG41090ED Protein with unknown function (DUF469) GSU80_RS14055 ENOG4105CEN a g-specific adenine glycosylase GSU80_RS14070 ENOG4105EAA nucleoside GSU80_RS14075 ENOG4105CXN decarboxylase GSU80_RS14080 ENOG4108UQV Membrane GSU80_RS14120 ENOG4105C2X Arabinose 5-phosphate isomerase GSU80_RS14125 ENOG4105ECX polysaccharide export GSU80_RS14130 ENOG4107V1M polysaccharide export protein GSU80_RS14135 ENOG4105CET Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity) GSU80_RS14140 ENOG4105E12 capsule polysaccharide GSU80_RS14145 ENOG41084CK capsule polysaccharide GSU80_RS14185 ENOG41090SZ ABC-2 type transporter GSU80_RS14190 ENOG4105U1E general secretion pathway protein M GSU80_RS14210 ENOG4105X5Z General secretion pathway protein I GSU80_RS14220 ENOG4108VAU general secretion pathway protein G GSU80_RS14225 ENOG4105D7Q type ii secretion system GSU80_RS14230 ENOG4107QHF type ii secretion system protein e GSU80_RS14245 ENOG410765S (LipO)protein GSU80_RS14250 ENOG4105EHH Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity) GSU80_RS14255 ENOG4105F88 accessory colonization factor AcfD GSU80_RS14260 ENOG4105DAA L-lactate GSU80_RS14265 ENOG4107QP3 malate synthase g GSU80_RS14270 ENOG4108ZJF Glcg protein GSU80_RS14275 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) GSU80_RS14280 ENOG4105EU8 FAD linked oxidase domain protein GSU80_RS14285 ENOG4105CQB FAD linked oxidase domain protein GSU80_RS14290 ENOG4108KWP DNA-binding transcriptional regulator GlcC GSU80_RS14300 ENOG4107RCI amp-dependent synthetase and ligase GSU80_RS14310 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) GSU80_RS14315 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) GSU80_RS14325 ENOG4108M8S permease YjgP YjgQ family protein GSU80_RS14330 ENOG4108UUE Transcriptional regulator GSU80_RS14340 ENOG4108S55 polysaccharide biosynthesis protein GSU80_RS14345 ENOG4106FPV ATP-binding protein YghR GSU80_RS14350 ENOG4108NDC ATP-binding protein yghS GSU80_RS14355 ENOG4108GH0 ATP-binding protein yghT GSU80_RS14360 ENOG4105CJ3 phosphate transporter GSU80_RS14365 ENOG4106032 Glutathionylspermidine synthase GSU80_RS14370 ENOG4105CYM Glutathione S-transferase GSU80_RS14375 ENOG41082MF Hydrogenase assembly chaperone hypC hupF GSU80_RS14380 ENOG4105WMM Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) GSU80_RS14385 ENOG4108WGS hydrogenase 2-specific chaperone GSU80_RS14390 ENOG4108USZ hydrogenase GSU80_RS14395 ENOG4105DPX Hydrogenase, large subunit GSU80_RS14400 ENOG4105CJ5 hydrogenase 2 b cytochrome subunit GSU80_RS14405 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein GSU80_RS14410 ENOG4105E3S small subunit GSU80_RS14415 ENOG410900S Protein of unknown function (DUF2623) GSU80_RS14425 ENOG4105CPC Aldo Keto reductase GSU80_RS14435 ENOG4105CYX Short-chain dehydrogenase reductase Sdr GSU80_RS14440 ENOG4108ZZF transport protein (ExbD) GSU80_RS14445 ENOG4105CWK Biopolymer transport protein, ExbB GSU80_RS14450 ENOG4105C28 cystathionine GSU80_RS14455 ENOG4108K81 inner membrane protein YghB GSU80_RS14460 ENOG4105CF7 AraC family transcriptional regulator GSU80_RS14465 ENOG4108I6A alcohol dehydrogenase GSU80_RS14470 ENOG4105CV8 reductase GSU80_RS14475 ENOG4105ZKC Conserved Protein GSU80_RS14485 ENOG4105CCT upf0313 protein GSU80_RS14490 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) GSU80_RS14495 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase GSU80_RS14500 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) GSU80_RS14505 ENOG4108J59 Extracellular solute-binding protein, family 5 GSU80_RS14510 ENOG4105WJ3 XRE family Transcriptional regulator GSU80_RS14515 ENOG4105RT5 Toxic component of a toxin-antitoxin (TA) module. An mRNA interferase which has been reported to be translation- independent (PubMed 19690171, PubMed 19943910) and translation- dependent (PubMed 20041169). Cleavage has been reported to occur on either side of G in the sequence GCU (PubMed 19690171) but also after C in GC(A U) sequences (PubMed 19943910). There are only 14 genes in E.coli W3110 (and probably also MG1655) that do not have a GCU sequence and thus are resistant to the mRNA interferase activity. Overexpression causes cessation of cell growth and inhibits cell proliferation via inhibition of translation as well as increasing persister cell formation GSU80_RS14520 ENOG4105F4I Transcriptional regulator GSU80_RS14525 ENOG4105H4F exported protein GSU80_RS14530 ENOG4105XJC Two component transcriptional regulator (Winged helix family GSU80_RS14535 ENOG4105DHQ Histidine kinase GSU80_RS14540 ENOG4107DEU Inner membrane protein YgiZ GSU80_RS14545 ENOG4105NF4 modulator of drug activity GSU80_RS14550 ENOG4105VRH Antibiotic biosynthesis monooxygenase GSU80_RS14555 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) GSU80_RS14560 ENOG4105IPS esterase GSU80_RS14565 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) GSU80_RS14570 ENOG4108SX3 cytoplasmic protein GSU80_RS14575 ENOG41087AY ADP-Ribose pyrophosphatase GSU80_RS14580 ENOG4105DFG type I secretion outer membrane protein GSU80_RS14590 ENOG4106032 Glutathionylspermidine synthase GSU80_RS14595 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b GSU80_RS14615 ENOG4105W0Z cytoplasmic protein GSU80_RS14620 ENOG4105H8W Fimbrial protein GSU80_RS14630 ENOG4108TTM chaperone GSU80_RS14635 ENOG4108MY7 Fimbrial GSU80_RS14645 ENOG4105PV3 Inner membrane protein yqiJ GSU80_RS14650 ENOG4107S78 Band 7 protein GSU80_RS14675 ENOG4105I7R Adenylate cyclase GSU80_RS14680 ENOG4106MWK domain protein GSU80_RS14690 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) GSU80_RS14695 ENOG4107ZVW dihydroneopterin aldolase GSU80_RS14705 ENOG4105EJC lysr family transcriptional regulator GSU80_RS14710 ENOG4106DSS Tartrate dehydratase subunit alpha GSU80_RS14715 ENOG4107GFK fumarate GSU80_RS14720 ENOG4107QPK )-transporter GSU80_RS14730 ENOG4105VCC 30S ribosomal protein S21 GSU80_RS14735 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) GSU80_RS14740 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) GSU80_RS14755 ENOG4105Q26 Siderophore-interacting protein GSU80_RS14760 ENOG4105NTW Transcriptional regulator GSU80_RS14765 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor GSU80_RS14775 ENOG4108Y51 tRNA-binding protein GSU80_RS14780 ENOG4105CQ4 Transcriptional regulator GSU80_RS14785 ENOG4105CNT hydrolase family 2 GSU80_RS14790 ENOG4105FK9 beta-D-galactosidase beta subunit GSU80_RS14795 ENOG4105E5D amino acid GSU80_RS14800 ENOG4107W6W Conserved Protein GSU80_RS14805 ENOG4107WCA isomerase GSU80_RS14810 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase GSU80_RS14815 ENOG4108Z3N Transcriptional regulator GSU80_RS14820 ENOG4105R48 this blockage is overcome by subsequent expression of antitoxin HigA. Overexpression causes cleavage of a number of mRNAs in a translation-dependent fashion, suggesting this is an mRNA interferase GSU80_RS14825 ENOG4105D8J Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity) GSU80_RS14830 ENOG4108VKG metal-dependent hydrolase GSU80_RS14835 ENOG4108UB4 uncharacterized protein ygjQ GSU80_RS14840 ENOG4105EE0 oxidoreductase GSU80_RS14845 ENOG4105DU1 integral membrane protein, terc GSU80_RS14850 ENOG4107QV7 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity) GSU80_RS14855 ENOG4105P66 Membrane GSU80_RS14860 ENOG4105CTX dehydratase GSU80_RS14870 ENOG4105DPW Major facilitator superfamily MFS_1 GSU80_RS14875 ENOG4107YCY Transcriptional regulator GSU80_RS14880 ENOG4106W5V Membrane GSU80_RS14885 ENOG4105IYR Modulates the activity of the EnvZ OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR (By similarity) GSU80_RS14890 ENOG4105WAY exported protein GSU80_RS14895 ENOG4105NE1 Conserved Protein GSU80_RS14900 ENOG41090KG Inner membrane protein YqjE GSU80_RS14905 ENOG4105YJD GSU80_RS14910 ENOG4108VBZ doxx family GSU80_RS14915 ENOG4105CHF Glutathione S-transferase GSU80_RS14920 ENOG4105KAF membrAne GSU80_RS14925 ENOG4105KAF membrAne GSU80_RS14930 ENOG4105CWB LysR family transcriptional Regulator GSU80_RS14935 ENOG4108CNN domain protein GSU80_RS14940 ENOG4106D80 Uncharacterized protein YhaL GSU80_RS14950 ENOG4105C44 Serine transporter GSU80_RS14955 ENOG4105EJQ L-serine dehydratase GSU80_RS14960 ENOG4105KME endoribonuclease L-psp GSU80_RS14965 ENOG4105C6N Formate acetyltransferase GSU80_RS14970 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) GSU80_RS14980 ENOG4105C7B Threonine dehydratase GSU80_RS14985 ENOG410811B TRANSCRIPTIONal GSU80_RS15010 ENOG4105BZW Glycerate kinase GSU80_RS15015 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase GSU80_RS15025 ENOG4105DJB Major Facilitator Superfamily GSU80_RS15030 ENOG4105CTX dehydratase GSU80_RS15035 ENOG4105ZEG Suppressor protein GSU80_RS15045 ENOG4105E98 transcriptional regulator DeoR family GSU80_RS15055 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB GSU80_RS15065 ENOG4105F3R pts system mannose fructose sorbose family iid GSU80_RS15070 ENOG4108YTN IIa component GSU80_RS15075 ENOG4105CE4 GlcNAc 6-P deacetylase GSU80_RS15080 ENOG4105E70 isomerase GSU80_RS15090 ENOG4108UZY PTS System GSU80_RS15095 ENOG4105ETZ PTS System GSU80_RS15100 ENOG4105F3R pts system mannose fructose sorbose family iid GSU80_RS15105 ENOG4106HBN Galactosamine-6-phosphate isomerase GSU80_RS15110 ENOG4105Q10 Fimbrial-like protein GSU80_RS15115 ENOG4108VCD Chaperone GSU80_RS15120 ENOG4105CW0 outer membrane usher protein GSU80_RS15125 ENOG4105I74 Fimbrial protein GSU80_RS15130 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) GSU80_RS15135 ENOG4105E1C Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity) GSU80_RS15145 ENOG4105F55 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity) GSU80_RS15150 ENOG4105W4M Transport-associated protein GSU80_RS15155 ENOG4107S21 permease GSU80_RS15160 ENOG4105K4T epimerase GSU80_RS15165 ENOG4107R7Y intracellular protease Pfpi family GSU80_RS15180 ENOG4108YYD acetyltransferase GSU80_RS15185 ENOG4105XPQ lipid carrier protein GSU80_RS15190 ENOG4105CFP Peptidase U32 GSU80_RS15195 ENOG4106RZ4 Peptidase U32 GSU80_RS15200 ENOG4105DEN Luciferase family GSU80_RS15205 ENOG4105CIC tryptophan-specific transport protein GSU80_RS15210 ENOG4105C1J atp-dependent rna helicase GSU80_RS15220 ENOG4105RT1 May be involved in cell division (By similarity) GSU80_RS15235 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) GSU80_RS15250 ENOG4105CHV Transcription elongation factor NusA GSU80_RS15270 ENOG4105DIJ Phosphoethanolamine transferase GSU80_RS15290 ENOG4105EEI dihydropteroate synthase GSU80_RS15295 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) GSU80_RS15300 ENOG4105F7M Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity) GSU80_RS15305 ENOG4105HBR Rna-binding protein GSU80_RS15310 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) GSU80_RS15315 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase GSU80_RS15325 ENOG4105QYV Membrane GSU80_RS15340 ENOG4105EAH synthase GSU80_RS15345 ENOG4105HVQ Regulatory factor of maltose metabolism GSU80_RS15355 ENOG4105VFK BolA family GSU80_RS15360 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane GSU80_RS15365 ENOG4105E3I toluene tolerance GSU80_RS15370 ENOG4107PE3 Mammalian cell entry related domain protein GSU80_RS15375 ENOG4105CY3 ABC transporter, permease GSU80_RS15380 ENOG4105DHJ ABC, transporter GSU80_RS15385 ENOG4105FEU K -dependent Na -Ca exchanger GSU80_RS15390 ENOG4105C2X Arabinose 5-phosphate isomerase GSU80_RS15400 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) GSU80_RS15405 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA GSU80_RS15410 ENOG4108IUZ ABC transporter GSU80_RS15415 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) GSU80_RS15420 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA GSU80_RS15425 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN GSU80_RS15435 ENOG41080Z8 PHOSPHOCARRIER protein GSU80_RS15440 ENOG4108NIH transferase activity, transferring phosphorus-containing groups GSU80_RS15450 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain GSU80_RS15455 ENOG4105BZU Histidine kinase GSU80_RS15460 ENOG4105N5T Radical SAM Protein GSU80_RS15465 ENOG4105CBC glutamate synthase GSU80_RS15470 ENOG4105BZ8 glutamate synthase GSU80_RS15475 ENOG4105DFS Conserved Protein GSU80_RS15485 ENOG4108R66 Conserved Protein GSU80_RS15490 ENOG41061DF Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P (By similarity) GSU80_RS15515 ENOG4105CEE C4-dicarboxylate transporter GSU80_RS15520 ENOG4105KB2 stringent starvation protein b GSU80_RS15525 ENOG4107MKT Stringent starvation protein a GSU80_RS15530 ENOG4108UJD 30S ribosomal protein S9 GSU80_RS15540 ENOG4105D6Z AFG1 family ATPase GSU80_RS15545 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III GSU80_RS15550 ENOG4105C0H protease GSU80_RS15555 ENOG4105C0H protease GSU80_RS15570 ENOG4105RID UPF0379 protein yhcN GSU80_RS15575 ENOG4105UNR (Barnase) inhibitor GSU80_RS15595 ENOG4105CR8 Transcriptional regulator GSU80_RS15600 ENOG4105D1U peptidase U62 modulator of DNA gyrase GSU80_RS15605 ENOG4105QD6 exported protein GSU80_RS15610 ENOG4105C03 ribonuclease GSU80_RS15615 ENOG4108Z03 MAF-like protein GSU80_RS15620 ENOG4105VQ7 Rod shape-determining protein MreD GSU80_RS15625 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) GSU80_RS15630 ENOG4105DFF Rod shape-determining protein mreb GSU80_RS15635 ENOG41062P1 Diguanylate cyclase phosphodiesterase GSU80_RS15640 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family GSU80_RS15645 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein GSU80_RS15650 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase GSU80_RS15655 ENOG4105RG0 Membrane GSU80_RS15660 ENOG4108IA2 Sodium pantothenate symporter GSU80_RS15670 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) GSU80_RS15675 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) GSU80_RS15680 ENOG4105CEC DNA methylase N-4 N-6 GSU80_RS15685 ENOG41061ME transport protein GSU80_RS15690 ENOG4108XG4 DNA-binding transcriptional regulator GSU80_RS15695 ENOG4105C1P efflux transporter, rnd family, mfp subunit GSU80_RS15700 ENOG4105BZS acriflavin resistance protein GSU80_RS15705 ENOG4105XCM membrane LIPOPROTEIN GSU80_RS15715 ENOG4105EZ7 amino acid ABC transporter GSU80_RS15720 ENOG4105DRP amino acid AbC transporter GSU80_RS15725 ENOG4105CDA abc transporter atp-binding protein GSU80_RS15765 ENOG4108Z0R Transferase GSU80_RS15770 ENOG4105SG3 Protein of unknown function (DUF1488) GSU80_RS15780 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) GSU80_RS15785 ENOG4108WI1 Dna topoisomerase GSU80_RS15795 ENOG4105C79 DNA protecting protein DprA GSU80_RS15815 ENOG4105C1A potassium transporter peripheral membrane GSU80_RS15825 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system GSU80_RS15830 ENOG4105W1Y Transcriptional regulator GSU80_RS15835 ENOG4105VTS DnaJ-like, subfamily C GSU80_RS15845 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) GSU80_RS15850 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) GSU80_RS15860 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits GSU80_RS15865 ENOG41067V7 50S ribosomal protein L36 GSU80_RS15870 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) GSU80_RS15875 ENOG4108UZ0 Binds to the 23S rRNA (By similarity) GSU80_RS15885 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) GSU80_RS15890 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) GSU80_RS15900 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) GSU80_RS15915 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) GSU80_RS15925 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal GSU80_RS15935 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) GSU80_RS15940 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) GSU80_RS15945 ENOG4105KAP The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) GSU80_RS15950 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) GSU80_RS15960 ENOG41080KG One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) GSU80_RS15965 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) GSU80_RS15980 ENOG4107ACA Calcium-binding protein required for initiation of chromosome replication GSU80_RS15985 ENOG410899B May play a regulatory role under conditions of derepressed gsp gene expression GSU80_RS15990 ENOG4107KSE General secretion pathway protein C GSU80_RS15995 ENOG4105GVR general secretion pathway protein D GSU80_RS16000 ENOG4107QHF type ii secretion system protein e GSU80_RS16005 ENOG4105D7Q type ii secretion system GSU80_RS16010 ENOG4108VAU general secretion pathway protein G GSU80_RS16015 ENOG41069X0 general secretion pathway protein h GSU80_RS16030 ENOG4105R04 type II secretion system protein K GSU80_RS16035 ENOG41063JA Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity) GSU80_RS16045 ENOG4105EHH Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity) GSU80_RS16050 ENOG4108UQY Iron-storage protein GSU80_RS16055 ENOG4105W53 bacterioferritin-associated ferredoxin GSU80_RS16060 ENOG4108NNZ chitinase GSU80_RS16100 ENOG4105WWK YheO domain protein GSU80_RS16105 ENOG4108V1T peptidylprolyl cis-trans isomerase GSU80_RS16115 ENOG4108YZY peptidylprolyl cis-trans isomerase GSU80_RS16120 ENOG4105VKU nucleicacid-binding protein GSU80_RS16135 ENOG4105C5H ABC transporter GSU80_RS16140 ENOG4105DNZ Alpha Beta Hydrolase GSU80_RS16150 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) GSU80_RS16155 ENOG4108UKZ OsmC family GSU80_RS16160 ENOG4107RYR Transcriptional regulator, Crp Fnr family GSU80_RS16165 ENOG410613R integral membrane protein, YccS YhfK family GSU80_RS16170 ENOG4105C8Y Acetylornithine aminotransferase GSU80_RS16175 ENOG4105DDQ anthranilate synthase GSU80_RS16180 ENOG4105MZU cell filamentation protein GSU80_RS16185 ENOG4106195 uncharacterized protein yhfG GSU80_RS16190 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) GSU80_RS16200 ENOG4107QZF nitrite reductase NADPH large subunit GSU80_RS16205 ENOG4105WZK nitrite reductase NADPH small subunit GSU80_RS16210 ENOG4107V9H nitrite transporter GSU80_RS16220 ENOG4105VYH GSU80_RS16225 ENOG4107QHQ amino acid GSU80_RS16230 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine GSU80_RS16235 ENOG4107Y0V Not clear, may be involved in an isomerization step GSU80_RS16240 ENOG4108KPW sugar kinase GSU80_RS16245 ENOG4105FDP GntR family transcriptional regulator GSU80_RS16250 ENOG4106PKC pyridoxal phosphate binding GSU80_RS16265 ENOG4106M0N transport system permease protein GSU80_RS16270 ENOG4105MUZ Protein of unknown function DUF2620 GSU80_RS16275 ENOG41080QX K07048 phosphotriesterase-related protein GSU80_RS16280 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) GSU80_RS16285 ENOG4108626 Racemase GSU80_RS16290 ENOG4105RMW regulation of transcription, DNA-dependent GSU80_RS16295 ENOG4108M21 GSU80_RS16300 ENOG4105C31 Tryptophanyl-tRNA synthetase GSU80_RS16305 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) GSU80_RS16310 ENOG4105DJV ribulose-phosphate 3-epimerase GSU80_RS16315 ENOG4105DFE Dna adenine methylase GSU80_RS16320 ENOG4105EGB membrane protein DamX GSU80_RS16335 ENOG4105E4G Type IV pilus GSU80_RS16340 ENOG4105ITY Required for the use of extracellular DNA as a nutrient GSU80_RS16345 ENOG4105XPX DNA utilization protein HofO GSU80_RS16350 ENOG41065NF Fimbrial assembly family protein GSU80_RS16355 ENOG4108U1Q Pilus assembly protein GSU80_RS16360 ENOG4108JQC penicillin-binding protein 1A GSU80_RS16365 ENOG4107RK2 ADP-ribose diphosphatase NudE GSU80_RS16370 ENOG4105DQY intracellular growth attenuator GSU80_RS16375 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 GSU80_RS16380 ENOG4105VEJ Heat shock protein GSU80_RS16390 ENOG4108MAJ Membrane GSU80_RS16400 ENOG4105E0F Histidine kinase GSU80_RS16405 ENOG4105DPZ Two component transcriptional regulator (Winged helix family GSU80_RS16410 ENOG4108RRZ Transcription elongation factor GreB GSU80_RS16415 ENOG4105BZM domain protein GSU80_RS16420 ENOG4105XFK Ferrous iron transport protein A GSU80_RS16425 ENOG4105CE1 Ferrous iron transport protein b GSU80_RS16435 ENOG4105DNE Transposase GSU80_RS16445 ENOG4105MJ2 Competence protein GSU80_RS16455 ENOG4105C6Z Gluconate GSU80_RS16460 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) GSU80_RS16465 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) GSU80_RS16480 ENOG4105E0Y RtcB Protein GSU80_RS16485 ENOG4105CYB regulatoR GSU80_RS16490 ENOG4105E98 transcriptional regulator DeoR family GSU80_RS16505 ENOG4105C6V Glycerol-3-phosphate dehydrogenase GSU80_RS16525 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) GSU80_RS16540 ENOG4108IUM Glycogen debranching enzyme GSU80_RS16550 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) GSU80_RS16555 ENOG41076UM multiple antibiotic resistance (MarC)-related protein GSU80_RS16560 ENOG4105C6Z Gluconate GSU80_RS16565 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family GSU80_RS16570 ENOG4105DIQ Transcriptional regulator GSU80_RS16580 ENOG4105C2I pirin domain protein GSU80_RS16585 ENOG4105D9R oxidoreductase GSU80_RS16590 ENOG4105WCN acetyltransferase GSU80_RS16595 ENOG4105GMB type VI secretion system effector, hcp1 family GSU80_RS16610 ENOG4106FA4 GSU80_RS16615 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) GSU80_RS16620 ENOG4105WC8 Conserved Protein GSU80_RS16625 ENOG4107T6V glycerophosphoryl diester phosphodiesterase GSU80_RS16630 ENOG4108IJ9 (ABC) transporter GSU80_RS16635 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component GSU80_RS16640 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component GSU80_RS16645 ENOG4105BZ7 extracellular solute-binding protein family 1 GSU80_RS16650 ENOG4108IV0 ABC, transporter GSU80_RS16655 ENOG4105C0Z ABC transporter GSU80_RS16660 ENOG4105CF8 branched-chain amino acid ABC transporter, permease GSU80_RS16665 ENOG4105C32 Amino acid ABC transporter (Permease) GSU80_RS16670 ENOG4105CP9 extracellular ligand-binding receptor GSU80_RS16675 ENOG4105U59 -acetyltransferase GSU80_RS16680 ENOG4105CP9 extracellular ligand-binding receptor GSU80_RS16685 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) GSU80_RS16690 ENOG4105CRP Part of the ABC transporter FtsEX involved in GSU80_RS16695 ENOG4105CAK Cell division ATP-binding protein ftsE GSU80_RS16700 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) GSU80_RS16705 ENOG4106H78 methyltransferase GSU80_RS16710 ENOG4105MG3 Membrane GSU80_RS16720 ENOG4107FS9 Membrane GSU80_RS16735 ENOG4105EX9 Membrane GSU80_RS16740 ENOG4108W1V Lipoprotein GSU80_RS16745 ENOG4105F9N Major Facilitator Superfamily GSU80_RS16750 ENOG4105DSF transport protein GSU80_RS16755 ENOG4107YAK holo-(acyl carrier protein) synthase 2 GSU80_RS16760 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein GSU80_RS16765 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component GSU80_RS16770 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component GSU80_RS16775 ENOG4106665 Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) GSU80_RS16790 ENOG4105CNA YD repeat protein GSU80_RS16800 ENOG4105NUP lyase containing HEAT-repeat GSU80_RS16805 ENOG410600T transposase GSU80_RS16810 ENOG4105CMI transporter GSU80_RS16815 ENOG4105CJ1 ABC, transporter GSU80_RS16820 ENOG4105D0S secretion protein (HlyD GSU80_RS16835 ENOG4107UNS conserved inner membrane protein GSU80_RS16840 ENOG4105CBX hi0933 family GSU80_RS16845 ENOG4105CJ3 phosphate transporter GSU80_RS16855 ENOG4108M6U Universal stress protein A GSU80_RS16860 ENOG4105DUX Transporter GSU80_RS16865 ENOG4105FFN Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity) GSU80_RS16870 ENOG4105DGW oligopeptidase A GSU80_RS16875 ENOG4105D6S protein involved in catabolism of external DNA GSU80_RS16880 ENOG4105DC8 reductase GSU80_RS16890 ENOG4105KBH arsR family transcriptional regulator GSU80_RS16895 ENOG4107R5R arsenical pump membrane protein GSU80_RS16900 ENOG4105K89 arsenate reductase GSU80_RS16910 ENOG4105Y4Z Outer Membrane Lipoprotein GSU80_RS16920 ENOG4105KT7 mgtC SapB transporter GSU80_RS16925 ENOG4105XXV Acid-resistance protein GSU80_RS16930 ENOG41060V2 Acid-resistance protein GSU80_RS16935 ENOG4108YK4 Acid-resistance membrane protein GSU80_RS16940 ENOG4106WJ0 Regulates the expression of several genes involved in acid resistance. Required for the expression of gadA and gadBC, among others, regardless of media or growth conditions. Binds directly to the 20 bp GAD box found in the control regions of both loci GSU80_RS16950 ENOG4105C1P efflux transporter, rnd family, mfp subunit GSU80_RS16955 ENOG4105BZS acriflavin resistance protein GSU80_RS16960 ENOG4105D3F AraC Family Transcriptional Regulator GSU80_RS16965 ENOG4108NKV transcriptional regulator GSU80_RS16970 ENOG4105CVK Glutamate decarboxylase GSU80_RS16975 ENOG4105CA0 peroxidase GSU80_RS16985 ENOG4106S2D Transcriptional regulator GSU80_RS16990 ENOG4105CBN LysR family transcriptional regulator GSU80_RS16995 ENOG4107H3J ribonuclease GSU80_RS17000 ENOG4105CSH Transporter GSU80_RS17005 ENOG41066T0 asmA family GSU80_RS17010 ENOG4105CMB EAL domain-containing protein GSU80_RS17020 ENOG4105CS0 peptidase GSU80_RS17030 ENOG4105BZU Histidine kinase GSU80_RS17035 ENOG4105EJG cellulose synthase GSU80_RS17040 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) GSU80_RS17045 ENOG4107EEX Cellulose synthase regulator protein GSU80_RS17050 ENOG4107QZ7 Cellulose synthase catalytic subunit GSU80_RS17060 ENOG410661M cytoplasmic protein GSU80_RS17065 ENOG4105U74 cellulose biosynthesis protein BcsE GSU80_RS17070 ENOG4105WQA Cellulose biosynthesis protein BcsF GSU80_RS17075 ENOG4105D1V cellulose synthase operon protein YhjU GSU80_RS17095 ENOG4105C44 Serine transporter GSU80_RS17100 ENOG4108JQ7 (ABC) transporter GSU80_RS17105 ENOG4105C3U ABC transporter GSU80_RS17110 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component GSU80_RS17115 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component GSU80_RS17120 ENOG4105DEF Extracellular solute-binding protein, family 5 GSU80_RS17135 ENOG4105DIJ Phosphoethanolamine transferase GSU80_RS17140 ENOG4105FCD Major Facilitator GSU80_RS17145 ENOG4105EAX Putative lipase GSU80_RS17150 ENOG4108R3E Dna-3-methyladenine glycosylase i GSU80_RS17155 ENOG4105HNP -acetyltransferase GSU80_RS17160 ENOG4107QY8 reductase GSU80_RS17165 ENOG4108ZG0 Ompa motb domain protein GSU80_RS17175 ENOG4106JH6 (LipO)protein GSU80_RS17180 ENOG4105MVF Transcriptional regulator GSU80_RS17185 ENOG4105VEQ Cold shock protein GSU80_RS17190 ENOG41060TC Hok gef cell toxic protein GSU80_RS17205 ENOG4108HMW glycyl-tRNA synthetase, alpha subunit GSU80_RS17215 ENOG4105MEV Acyl-transferase GSU80_RS17220 ENOG4108Z12 YiaAB two helix domain-containing protein GSU80_RS17225 ENOG410688U Inner membrane protein yiaB GSU80_RS17230 ENOG4105CMG Carbohydrate kinase GSU80_RS17240 ENOG4105DFW ABC transporter GSU80_RS17250 ENOG4107RNG ABC transporter GSU80_RS17255 ENOG4105T16 Transcriptional regulator (AraC family) GSU80_RS17260 ENOG4108UR8 BAX protein GSU80_RS17265 ENOG4107T9C Alpha amylase catalytic region GSU80_RS17270 ENOG4105JKW Valine--pyruvate aminotransferase GSU80_RS17275 ENOG4108XIB electron transport protein ysaA GSU80_RS17280 ENOG4105J4Q Transcriptional regulator GSU80_RS17290 ENOG4108R66 Conserved Protein GSU80_RS17295 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter GSU80_RS17300 ENOG4105CG6 trap dicarboxylate transporter dctm subunit GSU80_RS17305 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit GSU80_RS17310 ENOG4105CMG Carbohydrate kinase GSU80_RS17315 ENOG4105H6Q decarboxylase GSU80_RS17320 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase GSU80_RS17325 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase GSU80_RS17335 ENOG4105CT4 transporter GSU80_RS17345 ENOG4105GNX MltA-interacting MipA family protein GSU80_RS17350 ENOG4108Q2M Transcriptional regulator GSU80_RS17355 ENOG4105EFX secretion protein, HlyD family GSU80_RS17360 ENOG4105KK7 inner membrane protein YiaW GSU80_RS17370 ENOG4105C26 Dehydrogenase GSU80_RS17375 ENOG4105C0A alcohol dehydrogenase GSU80_RS17380 ENOG4105EM7 Selenocysteine-specific translation elongation factor GSU80_RS17390 ENOG4108U78 Glutathione S-transferase GSU80_RS17395 ENOG4105CNA YD repeat protein GSU80_RS17400 ENOG4105NUP lyase containing HEAT-repeat GSU80_RS17420 ENOG4105EFX secretion protein, HlyD family GSU80_RS17425 ENOG4105FP6 Protein of unknown function (DUF3302) GSU80_RS17430 ENOG4105CTS PTS system mannitol-specific GSU80_RS17440 ENOG4105E61 Mannitol repressor protein GSU80_RS17450 ENOG4108YYI Protein of unknown function (DUF2810) GSU80_RS17455 ENOG4108WY4 inner membrane lipoprotein GSU80_RS17460 ENOG4105EUR Domain-Containing protein GSU80_RS17465 ENOG4105DAA L-lactate GSU80_RS17470 ENOG41073TP transcriptional regulator GSU80_RS17480 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) GSU80_RS17485 ENOG4105D7W serine acetyltransferase GSU80_RS17500 ENOG4105VW4 glutaredoxin 3 GSU80_RS17505 ENOG4107YZP Rhodanese domain protein GSU80_RS17515 ENOG41063SB peptidase GSU80_RS17520 ENOG4105PXI polysaccharide deacetylase GSU80_RS17525 ENOG4105K64 Glycosyl transferase, family 2 GSU80_RS17535 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) GSU80_RS17545 ENOG4105XA0 heptosyltransferase ii GSU80_RS17550 ENOG4105D16 lipopolysaccharide heptosyltransferase i GSU80_RS17555 ENOG41068PG O-Antigen polymerase GSU80_RS17560 ENOG4105K64 Glycosyl transferase, family 2 GSU80_RS17565 ENOG4105X1N Glycosyl transferase family 8 GSU80_RS17590 ENOG4106AH0 Glycosyl Transferase GSU80_RS17595 ENOG4107543 (lipo)polysaccharide GSU80_RS17600 ENOG4107RJ7 Glycosyl transferase (Group 1 GSU80_RS17605 ENOG4105DKP glycosyl transferase, family 9 GSU80_RS17610 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase GSU80_RS17625 ENOG4105W0E 50S ribosomal protein L33 GSU80_RS17640 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase GSU80_RS17665 ENOG4105DSJ YicC domain protein GSU80_RS17670 ENOG4105F5P DNA-damage-inducible protein d GSU80_RS17675 ENOG4105EN6 Membrane GSU80_RS17680 ENOG410649J Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction (By similarity) GSU80_RS17685 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) GSU80_RS17690 ENOG4105VFG Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity) GSU80_RS17695 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) GSU80_RS17700 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase GSU80_RS17705 ENOG4105CB5 ATP-dependent DNA helicase recG GSU80_RS17715 ENOG4105D6U Sodium Glutamate Symporter GSU80_RS17720 ENOG4105C2W permease GSU80_RS17725 ENOG4105JV1 AsmA family GSU80_RS17730 ENOG4105CJQ hydrolase, family 31 GSU80_RS17735 ENOG4105CT4 transporter GSU80_RS17745 ENOG4105DFP Integrase GSU80_RS17755 ENOG4105CQ4 Transcriptional regulator GSU80_RS17760 ENOG4105DPW Major facilitator superfamily MFS_1 GSU80_RS17770 ENOG4108UUM single-stranded DNA-binding protein GSU80_RS17845 ENOG4105S8Q sugar efflux transporter GSU80_RS17850 ENOG4108UZ3 Transporter GSU80_RS17855 ENOG4105D01 (LipO)protein GSU80_RS17860 ENOG4105T8A Uncharacterized protein YicS GSU80_RS17870 ENOG4108SAJ Protein of unknown function (DUF1198) GSU80_RS17875 ENOG4105C7N Xanthine uracil vitamin C permease GSU80_RS17885 ENOG4105CXY transporter GSU80_RS17890 ENOG4105CXY transporter GSU80_RS17895 ENOG4105BZU Histidine kinase GSU80_RS17900 ENOG4108KX4 response regulator GSU80_RS17905 ENOG4105M71 acetolactate synthase 1 regulatory subunit GSU80_RS17910 ENOG4105C7K acetolactate synthase GSU80_RS17925 ENOG4105E5M Multidrug resistance protein D GSU80_RS17930 ENOG4105J13 transcriptional regulator GSU80_RS17935 ENOG4105JP4 Inner membrane protein yidG GSU80_RS17940 ENOG4105VG5 Membrane GSU80_RS17945 ENOG4106DRA Inner membrane protein YidI GSU80_RS17950 ENOG4105CBG Sulfatase GSU80_RS17955 ENOG4107RUZ Sss sodium solute transporter superfamily GSU80_RS17960 ENOG4108AHD Transcriptional regulator GSU80_RS17965 ENOG4105F8D glycoside hydrolase family 4 GSU80_RS17970 ENOG4105CI1 PTS System GSU80_RS17995 ENOG4105R2A (LipO)protein GSU80_RS18000 ENOG4105D99 atp gtp-binding protein GSU80_RS18010 ENOG4105DJB Major Facilitator Superfamily GSU80_RS18020 ENOG4108RTU Aldolase GSU80_RS18025 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 GSU80_RS18030 ENOG4105EMF GntR family transcriptional regulator GSU80_RS18035 ENOG410657R replicase EC 2.7 GSU80_RS18040 ENOG410667J hydrolase GSU80_RS18045 ENOG4105VP5 Bacterial protein of unknown function (DUF937) GSU80_RS18050 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) GSU80_RS18060 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) GSU80_RS18110 ENOG4108P6C Tryptophan transporter of low affinity GSU80_RS18125 ENOG4105E8Q phosphopantetheinyl transferase GSU80_RS18130 ENOG4108YYH Nadph-dependent fmn reductase GSU80_RS18135 ENOG4105C7N Xanthine uracil vitamin C permease GSU80_RS18140 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 GSU80_RS18150 ENOG4106611 bacteriocin immunity GSU80_RS18155 ENOG4107VKM 6-phosphogluconolactonase GSU80_RS18160 ENOG4105DYC esterase GSU80_RS18170 ENOG4105CS2 ec 3.2.1.21 GSU80_RS18175 ENOG4105C5Y PTS System GSU80_RS18180 ENOG4105CID antiterminator GSU80_RS18185 ENOG4108UTW Plays a role in the regulation of phosphate uptake GSU80_RS18190 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) GSU80_RS18195 ENOG4105E2Z phosphate ABC transporter (Permease GSU80_RS18200 ENOG4105C8U phosphate abc transporter GSU80_RS18205 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) GSU80_RS18210 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) GSU80_RS18250 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) GSU80_RS18260 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation GSU80_RS18275 ENOG4105QTB Flavodoxin GSU80_RS18280 ENOG4108VVK transcriptional Regulator, AsnC GSU80_RS18295 ENOG4107R4Q Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity) GSU80_RS18320 ENOG4105C2J ABC transporter GSU80_RS18325 ENOG4105CNN ABC, transporter GSU80_RS18330 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator GSU80_RS18335 ENOG4108RVA ribokinase GSU80_RS18340 ENOG4105ETE Transcriptional regulator (LacI family GSU80_RS18345 ENOG4105C0R drug resistance transporter emrb qaca subfamily GSU80_RS18350 ENOG4107EJG GntR family transcriptional regulator GSU80_RS18390 ENOG4108WFC UPF0438 protein yifE GSU80_RS18395 ENOG4105C0P Mg chelatase subunit ChlI GSU80_RS18415 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit GSU80_RS18420 ENOG4105CM2 brancheD-chain amino acid aminotransferase GSU80_RS18430 ENOG4105C7B Threonine dehydratase GSU80_RS18435 ENOG4105EMY transcriptional regulator GSU80_RS18445 ENOG4105KQ5 peptidylprolyl cis-trans isomerase GSU80_RS18455 ENOG4105C4R Atp-dependent dna helicase GSU80_RS18470 ENOG4105K63 Thioredoxin GSU80_RS18485 ENOG4105ESV Glycosyl transferase, family 4 GSU80_RS18490 ENOG4105SFE lipopolysaccharide biosynthesis protein GSU80_RS18495 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase GSU80_RS18500 ENOG4108IJ1 Dehydrogenase GSU80_RS18505 ENOG4105C1B dTDP-glucose 4-6-dehydratase GSU80_RS18510 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) GSU80_RS18515 ENOG4108WJ1 acetyltransferase GSU80_RS18520 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase GSU80_RS18525 ENOG4105EGZ biosynthesis protein GSU80_RS18530 ENOG4105F18 Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis (By similarity) GSU80_RS18545 ENOG4105C85 amino acid GSU80_RS18570 ENOG4105C4X radical SAM domain protein GSU80_RS18575 ENOG4105ENH Sulfatase GSU80_RS18580 ENOG410601J HemY protein GSU80_RS18585 ENOG4105ECF c-methyltransferase GSU80_RS18590 ENOG41076E6 Uroporphyrinogen-III Synthase GSU80_RS18600 ENOG4107T0K Adenylate cyclase GSU80_RS18615 ENOG4105S7Z (LipO)protein GSU80_RS18625 ENOG4105CT0 Protein of unknown function, DUF484 GSU80_RS18635 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant GSU80_RS18640 ENOG4105C4R Atp-dependent dna helicase GSU80_RS18645 ENOG4107V4F S-adenosyl-l-methionine hydroxide adenosyltransferase GSU80_RS18650 ENOG4108T58 Mg2 transport protein CorA GSU80_RS18655 ENOG4107QUT magnesium and cobalt transport protein CorA GSU80_RS18670 ENOG4107QUT magnesium and cobalt transport protein CorA GSU80_RS18675 ENOG4105NRM Membrane GSU80_RS18685 ENOG4105FR1 rard protein GSU80_RS18690 ENOG4108VUY thioesterase Superfamily protein GSU80_RS18695 ENOG4105HDD phospholipase GSU80_RS18700 ENOG4105C9U ATP-dependent DNA helicase RecQ GSU80_RS18715 ENOG4108EUD Lysophospholipase GSU80_RS18720 ENOG4105DQF Hydrolase GSU80_RS18725 ENOG4105EMK carboxylate amino acid amine transporter GSU80_RS18730 ENOG4105DZ2 Transcriptional regulator GSU80_RS18735 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) GSU80_RS18740 ENOG4105F52 Transcriptional regulator GSU80_RS18745 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin GSU80_RS18755 ENOG4105C5B carbamate kinase GSU80_RS18760 ENOG4107REC cytoplasmic protein GSU80_RS18765 ENOG4107R1Q Membrane protein FdrA GSU80_RS18775 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) GSU80_RS18780 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) GSU80_RS18785 ENOG4108I5U Uridine phosphorylase GSU80_RS18800 ENOG4105JN3 extra-cytoplasmic solute receptor family protein GSU80_RS18805 ENOG4108RTU Aldolase GSU80_RS18810 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 GSU80_RS18815 ENOG4107HP6 Transcriptional regulator GSU80_RS18820 ENOG4105CGY Dna recombination protein GSU80_RS18830 ENOG4105JC1 sterol-binding domain protein GSU80_RS18840 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) GSU80_RS18845 ENOG4105X8U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity) GSU80_RS18850 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) GSU80_RS18855 ENOG4105F8V Hydrolase, tatD family GSU80_RS18860 ENOG4105MDZ Transcriptional activator rfaH GSU80_RS18865 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) GSU80_RS18870 ENOG4107QK7 reductase GSU80_RS18890 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein GSU80_RS18895 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) GSU80_RS18900 ENOG4108RR8 protoporphyrinogen oxidase GSU80_RS18930 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b GSU80_RS18935 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) GSU80_RS18940 ENOG4105PC1 Conserved Protein GSU80_RS18945 ENOG4105E27 serine threonine protein kinase GSU80_RS18950 ENOG4108Z33 Thiol disulfide Interchange Protein GSU80_RS18960 ENOG4106HNH Acyl-transferase GSU80_RS18970 ENOG4105C2M dna polymerase I GSU80_RS18985 ENOG4105D4P Coproporphyrinogen iii oxidase GSU80_RS18990 ENOG4106FIY GSU80_RS18995 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family GSU80_RS19000 ENOG4105CUX Signal transduction histidine kinase GSU80_RS19005 ENOG4105C5F glutamine synthetase GSU80_RS19015 ENOG4108K85 Transcriptional regulator GSU80_RS19020 ENOG4108KHF Resistance protein GSU80_RS19025 ENOG4105R9B Major Facilitator GSU80_RS19030 ENOG4108KUC Outer membrane channel protein that allows an efficient diffusion of low-molecular-weight solutes such as small sugars and tetraglycine. However, the specific substrate recognized by the OmpL channel is GSU80_RS19035 ENOG4105CT4 transporter GSU80_RS19040 ENOG4105CT4 transporter GSU80_RS19045 ENOG4105CJQ hydrolase, family 31 GSU80_RS19050 ENOG4107WI4 Aldose-1-epimerase GSU80_RS19055 ENOG4107QKS N-acylglucosamine 2-epimerase GSU80_RS19060 ENOG4105D2M Aldolase GSU80_RS19065 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase GSU80_RS19070 ENOG4108MGF sugar kinase GSU80_RS19075 ENOG4105E98 transcriptional regulator DeoR family GSU80_RS19080 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 GSU80_RS19095 ENOG4105SUU thioesterase domain GSU80_RS19100 ENOG4106UEE Transcriptional regulator GSU80_RS19105 ENOG41068KX affects formate dehydrogenase-N GSU80_RS19115 ENOG4108MG3 formate dehydrogenase GSU80_RS19120 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein GSU80_RS19135 ENOG4108V87 frv operon regulatory protein GSU80_RS19140 ENOG4106C3V frv operon regulatory protein GSU80_RS19145 ENOG4105CN9 Peptidase m42 family protein GSU80_RS19150 ENOG4105DM4 PTS System GSU80_RS19155 ENOG41064BA PTS system, fructose-specific, IIA component GSU80_RS19200 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) GSU80_RS19210 ENOG4108RPX mosc domain containing protein GSU80_RS19215 ENOG4105E0F Histidine kinase GSU80_RS19220 ENOG4105E3W Two component transcriptional regulator (Winged helix family GSU80_RS19225 ENOG4105FMW periplasmic GSU80_RS19240 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein GSU80_RS19255 ENOG4105EBK exported protein GSU80_RS19260 ENOG4108VTS Membrane GSU80_RS19265 ENOG41065TG regulatoR GSU80_RS19275 ENOG4105DP0 ferredoxin-NADP reductase GSU80_RS19280 ENOG4105CBT Fructose-1,6-bisphosphatase GSU80_RS19290 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) GSU80_RS19305 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase GSU80_RS19310 ENOG4105C4N this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity) GSU80_RS19320 ENOG41063M6 Cell Division Protein GSU80_RS19325 ENOG4105ETE Transcriptional regulator (LacI family GSU80_RS19330 ENOG4105C25 Primosomal protein n' GSU80_RS19345 ENOG4107S01 Repressor protein MetJ GSU80_RS19355 ENOG4105C28 cystathionine GSU80_RS19360 ENOG4105CFH Aspartokinase GSU80_RS19365 ENOG4105SYT Methylenetetrahydrofolate reductase GSU80_RS19370 ENOG4105C1X Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity) GSU80_RS19375 ENOG4108Q5Y Membrane GSU80_RS19380 ENOG4108XC3 NADH ubiquinone oxidoreductase GSU80_RS19385 ENOG4105DCT glycerol dehydrogenase GSU80_RS19390 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) GSU80_RS19395 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) GSU80_RS19400 ENOG4105DM4 PTS System GSU80_RS19405 ENOG4108YRF PTS System GSU80_RS19410 ENOG4105C6N Formate acetyltransferase GSU80_RS19415 ENOG4108AHH pyruvate formate lyase II activase GSU80_RS19420 ENOG4108XCZ PTS System GSU80_RS19425 ENOG4106R3P AraC family transcriptional regulator GSU80_RS19430 ENOG4105DIJ Phosphoethanolamine transferase GSU80_RS19445 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase GSU80_RS19450 ENOG4105CAS nag kinase GSU80_RS19460 ENOG4105C5Q Transcriptional regulator GSU80_RS19470 ENOG4105EJ2 Transcriptional regulator GSU80_RS19475 ENOG4108Y73 Membrane GSU80_RS19520 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase GSU80_RS19555 ENOG4105PM1 preprotein translocase subunit SecE GSU80_RS19560 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) GSU80_RS19595 ENOG410645W Thiamin biosynthesis protein ThiH GSU80_RS19600 ENOG4105D41 biosynthesis protein thiH GSU80_RS19610 ENOG4105WHD thiamine biosynthesis protein ThiS GSU80_RS19615 ENOG4105D06 uba thif-type nad fad binding protein GSU80_RS19625 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) GSU80_RS19650 ENOG4105R2J Conserved Protein GSU80_RS19655 ENOG4105K70 DNA-binding protein GSU80_RS19660 ENOG4108T8B Protein of unknown function (DUF1481) GSU80_RS19665 ENOG4105JBU Binds zinc. Could be an important component of the zinc- balancing mechanism GSU80_RS19670 ENOG4105BZU Histidine kinase GSU80_RS19675 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family GSU80_RS19680 ENOG4105C12 Phosphoribosylglycinamide synthetase GSU80_RS19710 ENOG4105K5X acetyltransferase GSU80_RS19715 ENOG4105CVG Homoserine O-transsuccinylase GSU80_RS19720 ENOG4107QP3 malate synthase g GSU80_RS19725 ENOG4108I9X Isocitrate lyase GSU80_RS19730 ENOG4105VS7 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity) GSU80_RS19740 ENOG41069M3 Transcriptional regulator GSU80_RS19745 ENOG4105C3R Methionine synthase GSU80_RS19750 ENOG4105EAM Na Pi-cotransporter GSU80_RS19760 ENOG4105FE9 pseudouridine synthase GSU80_RS19765 ENOG4108ZR5 Conserved Protein GSU80_RS19770 ENOG4105CFH Aspartokinase GSU80_RS19785 ENOG4108MDC (LipO)protein GSU80_RS19790 ENOG4108Q9C Periplasmic Protein GSU80_RS19795 ENOG4105E3R (LipO)protein GSU80_RS19815 ENOG4107QNK )-transporter GSU80_RS19820 ENOG4105EG2 ABC transporter, permease GSU80_RS19825 ENOG4105D56 permease protein GSU80_RS19830 ENOG4107FKK extracellular solute-binding protein family 1 GSU80_RS19835 ENOG4108IJ9 (ABC) transporter GSU80_RS19845 ENOG4107W52 maltose operon periplasmic protein GSU80_RS19870 ENOG41080IJ Diacylglycerol kinase GSU80_RS19880 ENOG4107R73 Mate efflux family protein GSU80_RS19885 ENOG4105VDW Csbd family GSU80_RS19890 ENOG4105MYN Zinc uptake regulation protein GSU80_RS19905 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) GSU80_RS19910 ENOG4105P4Z Phage shock protein G GSU80_RS19915 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein GSU80_RS19920 ENOG4105CDU Replicative dna helicase GSU80_RS19925 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) GSU80_RS19930 ENOG4105CGF Aromatic amino acid aminotransferase GSU80_RS19940 ENOG4105F0S class B acid phosphatase GSU80_RS19945 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme GSU80_RS19950 ENOG4105MSB protein, conserved in bacteria GSU80_RS19955 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) GSU80_RS19960 ENOG4108UUM single-stranded DNA-binding protein GSU80_RS19965 ENOG4105PMV Membrane GSU80_RS19970 ENOG4108M8H domain protein GSU80_RS19975 ENOG4108W3Q Transcriptional regulator GSU80_RS19980 ENOG4108Z4X TRANSCRIPTIONal GSU80_RS19985 ENOG4105C7N Xanthine uracil vitamin C permease GSU80_RS19990 ENOG4105EEQ Na H antiporter GSU80_RS20005 ENOG41062QD Membrane GSU80_RS20010 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) GSU80_RS20020 ENOG4105JJ8 Cytochrome c nitrite reductase, pentaheme subunit GSU80_RS20025 ENOG4105D3S 4Fe-4S Ferredoxin, iron-sulfur binding domain protein GSU80_RS20030 ENOG4105DVI reductase, NrfD GSU80_RS20035 ENOG4108QKW cytochrome c-type biogenesis protein GSU80_RS20045 ENOG4108W0S formate-dependent nitrite reductase complex GSU80_RS20050 ENOG4105CK2 sodium dicarboxylate symporter GSU80_RS20055 ENOG41082ND Uncharacterized protein yjcO GSU80_RS20065 ENOG4105ETP RND efflux system, outer membrane lipoprotein GSU80_RS20070 ENOG4108MI0 Resistance protein GSU80_RS20075 ENOG4105J12 Multidrug resistance protein mdtN GSU80_RS20080 ENOG4106833 GSU80_RS20085 ENOG4105EUZ Beta-lactamase domain protein GSU80_RS20090 ENOG4107TFG D-allose kinase GSU80_RS20095 ENOG4105UP7 3-epimerase GSU80_RS20100 ENOG4105CNN ABC, transporter GSU80_RS20105 ENOG4105C2J ABC transporter GSU80_RS20110 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator GSU80_RS20115 ENOG4105NYY transcriptional regulator, RpiR GSU80_RS20120 ENOG4108YZG isomerase GSU80_RS20125 ENOG4106ZVZ Escherichia coli IMT2125 genomic chromosome, IMT2125 GSU80_RS20130 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein GSU80_RS20135 ENOG410849A acetyltransferase, (GNAT) family GSU80_RS20140 ENOG4105MFQ Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity) GSU80_RS20145 ENOG4105FD8 phosphonate metabolism protein PhnM GSU80_RS20150 ENOG4105HRV phosphonate c-p lyase system protein phnl GSU80_RS20155 ENOG4105ENV phosphonate C-P lyase system protein PhnK GSU80_RS20160 ENOG4105FT8 Phosphonate metabolism GSU80_RS20165 ENOG4105EKV Phosphonate metabolism protein GSU80_RS20170 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH GSU80_RS20175 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG GSU80_RS20180 ENOG4107RJJ Transcriptional regulator GSU80_RS20190 ENOG4105EHI Phosphonate ABC transporter, periplasmic GSU80_RS20195 ENOG4105D5T phosphonate abc transporter GSU80_RS20200 ENOG4108SQ4 Glyoxalase Bleomycin resistance protein (Dioxygenase GSU80_RS20205 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA GSU80_RS20210 ENOG4108F5E vimentin GSU80_RS20215 ENOG4108YIV GSU80_RS20220 ENOG4105CSH Transporter GSU80_RS20230 ENOG4105ECM Sensor protein basS pmrB GSU80_RS20235 ENOG4105XJC Two component transcriptional regulator (Winged helix family GSU80_RS20240 ENOG4105DIJ Phosphoethanolamine transferase GSU80_RS20245 ENOG4105D5Q Arginine ornithine antiporter GSU80_RS20250 ENOG4106ZGR Transcriptional regulator GSU80_RS20255 ENOG4105CXN decarboxylase GSU80_RS20260 ENOG4108K2B transcriptional regulator GSU80_RS20265 ENOG4105F8D glycoside hydrolase family 4 GSU80_RS20270 ENOG4105CT4 transporter GSU80_RS20275 ENOG4108R5S membrane GSU80_RS20280 ENOG4107GFK fumarate GSU80_RS20285 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter GSU80_RS20290 ENOG4108MRH transcriptional regulatory protein GSU80_RS20300 ENOG4105VR1 Pfam:DUF1271 GSU80_RS20305 ENOG410830R acetyltransferase GSU80_RS20320 ENOG4105CRK lysyL-tRNA synthetase GSU80_RS20325 ENOG4105DUX Transporter GSU80_RS20330 ENOG4105CXN decarboxylase GSU80_RS20335 ENOG4105D5Q Arginine ornithine antiporter GSU80_RS20340 ENOG4108M3R transcriptional activator CadC GSU80_RS20350 ENOG4108SIC Transcriptional regulator GSU80_RS20365 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter GSU80_RS20370 ENOG4108IJ0 Aspartate ammonia-lyase GSU80_RS20375 ENOG4108YH1 overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7 GSU80_RS20380 ENOG4105DVH amino acid GSU80_RS20395 ENOG4108ZVF (LipO)protein GSU80_RS20400 ENOG4105MTB Uncharacterized protein YjeJ GSU80_RS20405 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein GSU80_RS20415 ENOG4106HKS Entericidin EcnA/B family GSU80_RS20420 ENOG4106BSU Entericidin B GSU80_RS20425 ENOG4105KPY Small multidrug resistance protein GSU80_RS20430 ENOG4105QNF Outer membrane lipoprotein GSU80_RS20435 ENOG41066YJ Beta-lactamase GSU80_RS20450 ENOG4105E33 succinate dehydrogenase GSU80_RS20455 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) GSU80_RS20465 ENOG4107SC7 Inner membrane transporter yjeM GSU80_RS20470 ENOG4105EGS Mechanosensitive ion channel GSU80_RS20510 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) GSU80_RS20515 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) GSU80_RS20520 ENOG4105K8N protein family UPF0079, ATPase GSU80_RS20525 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase GSU80_RS20540 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) GSU80_RS20545 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) GSU80_RS20550 ENOG4107QJR hflk protein GSU80_RS20555 ENOG4105EPW hflc protein GSU80_RS20575 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) GSU80_RS20580 ENOG4105C2N RNA methyltransferase TrmH family group 3 GSU80_RS20585 ENOG4105FUX Conserved Protein GSU80_RS20590 ENOG4108P9J Phage shock protein A GSU80_RS20595 ENOG4107VNS Protein of unknown function (DUF2491) GSU80_RS20600 ENOG4105Z6B inner membrane protein yjfl GSU80_RS20605 ENOG4108KXT Conserved Protein GSU80_RS20610 ENOG4106032 Glutathionylspermidine synthase GSU80_RS20615 ENOG4105CSU acyl-Coa dehydrogenase GSU80_RS20620 ENOG4105S17 UPF0379 protein yjfN GSU80_RS20625 ENOG4105WSB biofilm stress and motility protein A GSU80_RS20630 ENOG4108MXZ Esterase GSU80_RS20645 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC GSU80_RS20650 ENOG410907W The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in ascorbate transport GSU80_RS20675 ENOG4105KIT UPF0379 protein yjfY GSU80_RS20690 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) GSU80_RS20700 ENOG4105DPW Major facilitator superfamily MFS_1 GSU80_RS20705 ENOG4107S3R L-aspartate oxidase GSU80_RS20710 ENOG4107R0K CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) GSU80_RS20715 ENOG4105E39 Enoyl-CoA hydratase GSU80_RS20725 ENOG4105CHR reductase GSU80_RS20735 ENOG4105FHY Opacity-associated protein A GSU80_RS20740 ENOG4108V1T peptidylprolyl cis-trans isomerase GSU80_RS20745 ENOG4105C85 amino acid GSU80_RS20755 ENOG4105DXC membrane GSU80_RS20760 ENOG4105ECR NmrA family GSU80_RS20765 ENOG4105KVH Transcriptional regulator GSU80_RS20770 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic GSU80_RS20775 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase GSU80_RS20780 ENOG4108UUE Transcriptional regulator GSU80_RS20785 ENOG41061GZ Protein of unknown function (DUF1107) GSU80_RS20790 ENOG4105C37 (CBS) domain GSU80_RS20800 ENOG4105CFU surface antigen GSU80_RS20805 ENOG4105MA0 exported protein GSU80_RS20810 ENOG4108ZHD aig2 family GSU80_RS20815 ENOG4105F0N pyrophosphate phospho-hydrolase GSU80_RS20820 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator GSU80_RS20825 ENOG4105C2J ABC transporter GSU80_RS20830 ENOG4107R9N ABC transporter GSU80_RS20835 ENOG41062B0 ABC transporter, permease GSU80_RS20845 ENOG4105DFU Cell wall formation (By similarity) GSU80_RS20855 ENOG4105CMS peptidase U62, modulator of DNA gyrase GSU80_RS20865 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) GSU80_RS20870 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase GSU80_RS20875 ENOG4105CG3 alpha amylase, catalytic region GSU80_RS20880 ENOG4105C5Y PTS System GSU80_RS20885 ENOG4105D4X repressor GSU80_RS20895 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic GSU80_RS20900 ENOG4105KME endoribonuclease L-psp GSU80_RS20915 ENOG41077AM PyrBI operon attenuator GSU80_RS20920 ENOG4108UQ8 endoribonuclease L-psp GSU80_RS20925 ENOG4105F6U Short-chain dehydrogenase reductase Sdr GSU80_RS20930 ENOG4108XFH Transcriptional regulator GSU80_RS20935 ENOG4105XEP YhcH YjgK YiaL family protein GSU80_RS20950 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) GSU80_RS20955 ENOG4108MJ3 acetyltransferase GSU80_RS20960 ENOG4108M3P Membrane GSU80_RS20965 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) GSU80_RS20970 ENOG4105MYG DNA polymerase iii, chi subunit GSU80_RS20980 ENOG4108M8S permease YjgP YjgQ family protein GSU80_RS20985 ENOG4108K5H permease YjgP YjgQ family protein GSU80_RS20990 ENOG4105D7A ATP-binding protein GSU80_RS20995 ENOG4105K2J Transcriptional regulator GSU80_RS21000 ENOG4105C6Z Gluconate GSU80_RS21005 ENOG4105CHR reductase GSU80_RS21010 ENOG4105CPQ Dehydrogenase GSU80_RS21015 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family GSU80_RS21020 ENOG4105DQ4 alcohol dehydrogenase GSU80_RS21045 ENOG4105VNT transposase (IS4 family) protein GSU80_RS21050 ENOG4105JHE Major Facilitator Superfamily GSU80_RS21055 ENOG4107RJ5 oxidoreductase GSU80_RS21085 ENOG4105C94 Transporter GSU80_RS21105 ENOG4105E0A ABC, transporter GSU80_RS21110 ENOG4108IHU transport system permease protein GSU80_RS21115 ENOG4105DQ5 transport system permease protein GSU80_RS21120 ENOG4108HUF Transporter GSU80_RS21125 ENOG4105GAV receptor GSU80_RS21130 ENOG4108S3W Anti-feci sigma factor, fecr GSU80_RS21135 ENOG4108SF5 RNA Polymerase GSU80_RS21165 ENOG4108PQ7 sgc region transcriptional regulator GSU80_RS21170 ENOG4108RK0 3-epimerase GSU80_RS21175 ENOG4108XBJ The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) GSU80_RS21180 ENOG4106P19 photosystem i assembly btpa GSU80_RS21185 ENOG4105DT3 PTS system, galactitol-specific IIc component GSU80_RS21190 ENOG4105K18 The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) GSU80_RS21195 ENOG4105CN9 Peptidase m42 family protein GSU80_RS21205 ENOG4105DTA methyltransferase GSU80_RS21210 ENOG41080VW acetyltransferase GSU80_RS21235 ENOG4108MX5 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity) GSU80_RS21240 ENOG41069FU Outer membrane channel protein allowing the entry of N- acetylneuraminic acid (Neu5Ac, the most abundant sialic acid on host cell surfaces) into the bacteria GSU80_RS21260 ENOG4105E71 FimE is one of the 2 regulatory proteins which control the phase variation of type 1 fimbriae in E.coli. These proteins mediate the periodic inversion of a 300bp DNA segment that harbors the promoter for the fimbrial structural gene, fimA. FimE switches fimA off GSU80_RS21265 ENOG4108RQP Major type 1 subunit fimbrin GSU80_RS21270 ENOG4108S54 Fimbrial protein GSU80_RS21275 ENOG4108NAE Fimbrial chaperone protein GSU80_RS21280 ENOG4105CW0 outer membrane usher protein GSU80_RS21285 ENOG4108SQA Fimbrial GSU80_RS21290 ENOG4108T65 Fimbrial GSU80_RS21295 ENOG410643X FIMH SUBUNIT MANNOSE-sensitive type 1 fimbrial adhesin GSU80_RS21300 ENOG4107EFN gluconate transport system permease 3 GSU80_RS21310 ENOG4105DEI Mannitol dehydrogenase GSU80_RS21315 ENOG4105C6F GntR Family Transcriptional Regulator GSU80_RS21335 ENOG4107YNJ LysR family Transcriptional regulator GSU80_RS21340 ENOG4105DYB Isoaspartyl dipeptidase GSU80_RS21345 ENOG4108P2H Inner membrane protein YjiG GSU80_RS21350 ENOG41074DU domain protein GSU80_RS21360 ENOG4105CBP Major Facilitator GSU80_RS21365 ENOG4108ZK4 sdia-regulated domain-containing protein GSU80_RS21375 ENOG4105CIZ coA-substrate-specific enzyme activase GSU80_RS21380 ENOG4105DCU 2-hydroxyglutaryl-CoA dehydratase GSU80_RS21385 ENOG4106BRA Membrane GSU80_RS21390 ENOG41083G8 Multidrug resistance protein MdtM GSU80_RS21410 ENOG4107SQC 5-methylcytosine-specific restriction enzyme subunit McrC GSU80_RS21415 ENOG4105FBQ ATPase associated with various cellular activities aaa_5 GSU80_RS21440 ENOG4105CVR type I restriction-modification system GSU80_RS21445 ENOG4107SCJ type I restriction enzyme EcoKI subunit R GSU80_RS21450 ENOG4106H3A restriction GSU80_RS21455 ENOG4105CKI cobalamin synthesis protein GSU80_RS21460 ENOG4105VCD cytoplasmic protein GSU80_RS21465 ENOG4105D22 carbon starvation protein GSU80_RS21470 ENOG4107UWN reductase GSU80_RS21475 ENOG4105EFA 4-hydroxyphenylacetate GSU80_RS21505 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase GSU80_RS21510 ENOG4105C26 Dehydrogenase GSU80_RS21515 ENOG4105ERH Fumarylacetoacetate hydrolase GSU80_RS21520 ENOG4108V8F Transcriptional regulator, MarR family GSU80_RS21525 ENOG4105C8Q Methyl-accepting chemotaxis GSU80_RS21530 ENOG4108I5G Major Facilitator superfamily GSU80_RS21540 ENOG4105CPQ Dehydrogenase GSU80_RS21550 ENOG4105RI1 glycoprotein receptor GSU80_RS21555 ENOG4106CVF DNA replication protein GSU80_RS21570 ENOG4105DWK Membrane GSU80_RS21575 ENOG4108N8T regulatoR GSU80_RS21580 ENOG4108T94 DNA-binding transcriptional activator BglJ GSU80_RS21585 ENOG4108819 ferric iron reductase GSU80_RS21590 ENOG4105YBH Protein of unknown function (DUF1435) GSU80_RS21615 ENOG4108WPU DNA polymerase III subunit psi GSU80_RS21620 ENOG4105KEG ribosomal-protein-alanine acetyltransferase GSU80_RS21625 ENOG4105PAD Hydrolase GSU80_RS21635 ENOG4105K3G Periplasmic Protein GSU80_RS21645 ENOG4108NRW Phospholipase, patatin family GSU80_RS21650 ENOG4105EYA deoxyribonuclease GSU80_RS21655 ENOG41076CZ activating enzyme GSU80_RS21660 ENOG4105G0K glycine radical enzyme YjjI family GSU80_RS21690 ENOG4107RMF Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity) GSU80_RS21695 ENOG4107RMF Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity) GSU80_RS21700 ENOG4105EAC phosphoserine phosphatase GSU80_RS21705 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) GSU80_RS21710 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase GSU80_RS21715 ENOG4105C5H ABC transporter GSU80_RS21720 ENOG4107SC1 transglycosylase GSU80_RS21730 ENOG4108K16 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) GSU80_RS21740 ENOG4105UEI Transcriptional Regulator AraC Family GSU80_RS21745 ENOG4108RH0 Crea protein GSU80_RS21750 ENOG4105E3W Two component transcriptional regulator (Winged helix family GSU80_RS21755 ENOG4105EB3 Histidine kinase GSU80_RS21760 ENOG4105CT7 inner membrane cred family protein GSU80_RS21765 ENOG41065U4 response regulator GSU80_RS21770 ENOG410759A GSU80_RS21775 ENOG4106FVC RNA methyltransferase