locus-tag	class	description
IN878_RS00035	COG2003	Belongs to the UPF0758 family
IN878_RS00305	COG3381	protein complex oligomerization
IN878_RS00315	COG1462	curli production assembly transport component CsgG
IN878_RS00330	COG2197	response regulator
IN878_RS00355	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
IN878_RS00360	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IN878_RS00375	COG2943	transferase activity, transferring hexosyl groups
IN878_RS00380	COG5645	(Lipo)protein
IN878_RS00395	COG1560	Kdo2-lipid A biosynthetic process
IN878_RS00405	COG2353	YceI-like domain
IN878_RS00410	COG3038	cytochrome b561
IN878_RS00445	COG2999	glutathione oxidoreductase activity
IN878_RS00455	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IN878_RS00465	COG0673	inositol 2-dehydrogenase activity
IN878_RS00470	COG0728	peptidoglycan biosynthetic process
IN878_RS00475	COG3418	PFAM FlgN family protein
IN878_RS00480	COG2747	anti-sigma28 factor FlgM
IN878_RS00485	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
IN878_RS00490	COG1815	bacterial-type flagellum-dependent cell motility
IN878_RS00495	COG1558	bacterial-type flagellum-dependent cell motility
IN878_RS00500	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
IN878_RS00505	COG1749	Flagellar hook protein flgE
IN878_RS00510	COG4787	bacterial-type flagellum-dependent cell motility
IN878_RS00515	COG4786	Flagellar basal body rod
IN878_RS00530	COG1705	Flagellar rod assembly protein muramidase FlgJ
IN878_RS00530	COG3951	Flagellar rod assembly protein muramidase FlgJ
IN878_RS00535	COG1256	bacterial-type flagellum assembly
IN878_RS00540	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IN878_RS00545	COG1530	ribonuclease E activity
IN878_RS00550	COG0564	pseudouridine synthase activity
IN878_RS00555	COG0424	maF-like protein
IN878_RS00560	COG1399	metal-binding, possibly nucleic acid-binding protein
IN878_RS00580	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IN878_RS00585	COG1028	Short-chain dehydrogenase reductase Sdr
IN878_RS00595	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IN878_RS00600	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IN878_RS00605	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IN878_RS00615	COG0470	DNA polymerase III
IN878_RS00620	COG0084	hydrolase, TatD family'
IN878_RS00625	COG1263	PTS System
IN878_RS00625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IN878_RS00630	COG4773	Receptor
IN878_RS00635	COG0537	adenosine 5'-monophosphoramidase activity
IN878_RS00640	COG5633	Lipoprotein
IN878_RS00645	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
IN878_RS00665	COG1252	NADH dehydrogenase
IN878_RS00670	COG3134	Outer membrane lipoprotein
IN878_RS00675	COG1309	transcriptional regulator
IN878_RS00685	COG1376	ErfK ybiS ycfS ynhG family protein
IN878_RS00685	COG1388	LysM domain
IN878_RS00690	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IN878_RS00695	COG4763	Acyl-transferase
IN878_RS00700	COG4591	ABC-type transport system involved in lipoprotein release permease component
IN878_RS00705	COG1136	(ABC) transporter
IN878_RS00710	COG4591	ABC-type transport system involved in lipoprotein release permease component
IN878_RS00720	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IN878_RS00725	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IN878_RS00735	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IN878_RS00740	COG1177	transmembrane transport
IN878_RS00750	COG3842	ATPase activity
IN878_RS00760	COG2850	peptidyl-arginine hydroxylation
IN878_RS00765	COG2205	protein histidine kinase activity
IN878_RS00770	COG0745	RESPONSE REGULATOR receiver
IN878_RS00775	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IN878_RS00795	COG1187	pseudouridine synthase activity
IN878_RS00800	COG0538	isocitrate dehydrogenase activity
IN878_RS00820	COG5562	phage envelope protein
IN878_RS00825	COG0789	Transcriptional regulator
IN878_RS00830	COG2200	EAL domain
IN878_RS00855	COG2200	EAL domain
IN878_RS00905	COG2894	cell division
IN878_RS00930	COG0179	Fumarylacetoacetate (FAA) hydrolase
IN878_RS00945	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IN878_RS00950	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IN878_RS00955	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
IN878_RS00970	COG2719	SpoVR family
IN878_RS00980	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IN878_RS00990	COG1619	proteins homologs of microcin C7 resistance protein MccF
IN878_RS01000	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
IN878_RS01005	COG2261	transglycosylase associated protein
IN878_RS01020	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IN878_RS01020	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
IN878_RS01020	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IN878_RS01025	COG1461	Dihydroxyacetone kinase
IN878_RS01030	COG2376	Dihydroxyacetone kinase
IN878_RS01035	COG3284	Transcriptional regulator
IN878_RS01040	COG3468	outer membrane autotransporter barrel domain protein
IN878_RS01045	COG0012	GTP binding
IN878_RS01060	COG0659	secondary active sulfate transmembrane transporter activity
IN878_RS01065	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IN878_RS01090	COG2890	protein-(glutamine-N5) methyltransferase activity
IN878_RS01095	COG3094	Invasion gene expression up-regulator, SirB
IN878_RS01100	COG2912	Transglutaminase-like superfamily
IN878_RS01125	COG0387	Pfam Sodium calcium exchanger
IN878_RS01130	COG4572	Cation transport regulator
IN878_RS01135	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
IN878_RS01140	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
IN878_RS01145	COG4932	domain protein
IN878_RS01150	COG2197	response regulator
IN878_RS01155	COG3850	Histidine kinase
IN878_RS01160	COG2223	nitrite transmembrane transporter activity
IN878_RS01165	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IN878_RS01170	COG1140	nitrate reductase beta subunit
IN878_RS01175	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
IN878_RS01180	COG2181	nitrate reductase activity
IN878_RS01215	COG0788	formyltetrahydrofolate deformylase activity
IN878_RS01225	COG1752	Esterase of the alpha-beta hydrolase superfamily
IN878_RS01230	COG0745	RESPONSE REGULATOR receiver
IN878_RS01235	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IN878_RS01245	COG1435	thymidine kinase activity
IN878_RS01255	COG1012	belongs to the aldehyde dehydrogenase family
IN878_RS01255	COG1454	alcohol dehydrogenase
IN878_RS01260	COG2095	MarC family integral membrane protein
IN878_RS01270	COG4166	transmembrane transport
IN878_RS01275	COG0601	transmembrane transport
IN878_RS01280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IN878_RS01285	COG0444	Belongs to the ABC transporter superfamily
IN878_RS01290	COG4608	Belongs to the ABC transporter superfamily
IN878_RS01310	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IN878_RS01315	COG2350	Protein conserved in bacteria
IN878_RS01320	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
IN878_RS01325	COG1607	acyl-coa hydrolase
IN878_RS01345	COG3047	cAMP biosynthetic process
IN878_RS01350	COG3685	Protein conserved in bacteria
IN878_RS01355	COG3685	Protein conserved in bacteria
IN878_RS01360	COG3729	General stress protein
IN878_RS01375	COG0134	indole-3-glycerol-phosphate synthase activity
IN878_RS01375	COG0135	phosphoribosylanthranilate isomerase activity
IN878_RS01380	COG0512	Glutamine amidotransferase of anthranilate synthase
IN878_RS01380	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IN878_RS01385	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IN878_RS01395	COG0613	PHP domain protein
IN878_RS01400	COG0009	L-threonylcarbamoyladenylate synthase
IN878_RS01405	COG4907	membrane protein (DUF2207)
IN878_RS01410	COG1187	pseudouridine synthase activity
IN878_RS01415	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
IN878_RS01420	COG1028	Short-chain dehydrogenase reductase Sdr
IN878_RS01425	COG0616	signal peptide processing
IN878_RS01435	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IN878_RS01440	COG0583	DNA-binding transcription factor activity
IN878_RS01460	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IN878_RS01470	COG0671	phosphoesterase, PA-phosphatase related
IN878_RS01475	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
IN878_RS01480	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
IN878_RS01490	COG0023	Translation Initiation Factor
IN878_RS01500	COG1349	DNA-binding transcription factor activity
IN878_RS01510	COG5001	Diguanylate cyclase
IN878_RS01525	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IN878_RS01525	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IN878_RS01530	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IN878_RS01535	COG2852	Protein conserved in bacteria
IN878_RS01540	COG4172	Belongs to the ABC transporter superfamily
IN878_RS01545	COG4172	Belongs to the ABC transporter superfamily
IN878_RS01550	COG4171	peptide transport system, permease
IN878_RS01555	COG4168	peptide transport system, permease
IN878_RS01560	COG4166	transmembrane transport
IN878_RS01570	COG0531	amino acid
IN878_RS01580	COG0174	glutamine synthetase
IN878_RS01585	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IN878_RS01590	COG1917	Cupin 2, conserved barrel domain protein
IN878_RS01590	COG1396	sequence-specific DNA binding
IN878_RS01595	COG1012	belongs to the aldehyde dehydrogenase family
IN878_RS01600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IN878_RS01605	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IN878_RS01610	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
IN878_RS01615	COG1842	Phage shock protein A
IN878_RS01625	COG1983	PspC domain protein
IN878_RS01635	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IN878_RS01640	COG0366	Alpha amylase catalytic
IN878_RS01645	COG1653	transport
IN878_RS01650	COG1175	transmembrane transport
IN878_RS01655	COG0395	ABC-type sugar transport system, permease component
IN878_RS01660	COG1063	alcohol dehydrogenase
IN878_RS01665	COG1082	Xylose isomerase domain protein TIM barrel
IN878_RS01670	COG0673	inositol 2-dehydrogenase activity
IN878_RS01675	COG1554	hydrolase, family 65, central catalytic
IN878_RS01680	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IN878_RS01685	COG3842	ATPase activity
IN878_RS01695	COG1609	Transcriptional regulator
IN878_RS01700	COG3106	COG3106 Predicted ATPase
IN878_RS01710	COG3283	Transcriptional regulator of aromatic amino acids metabolism
IN878_RS01715	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IN878_RS01720	COG4948	Mandelate Racemase Muconate Lactonizing
IN878_RS01725	COG2866	Carboxypeptidase
IN878_RS01740	COG0583	DNA-binding transcription factor activity
IN878_RS01745	COG4166	transmembrane transport
IN878_RS01750	COG0668	transmembrane transport
IN878_RS01755	COG3182	Iron-regulated membrane protein
IN878_RS01760	COG0589	response to stress
IN878_RS01765	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IN878_RS01770	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IN878_RS01775	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
IN878_RS01780	COG1473	amidohydrolase
IN878_RS01785	COG1473	amidohydrolase
IN878_RS01790	COG0583	DNA-binding transcription factor activity
IN878_RS01795	COG2840	Smr protein MutS2
IN878_RS01800	COG3706	GGDEF domain
IN878_RS01810	COG0513	Belongs to the DEAD box helicase family
IN878_RS01820	COG0589	response to stress
IN878_RS01825	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IN878_RS01830	COG0674	pyruvate-flavodoxin oxidoreductase activity
IN878_RS01830	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IN878_RS01830	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
IN878_RS01830	COG1013	pyruvate-flavodoxin oxidoreductase activity
IN878_RS01835	COG3042	response to heat
IN878_RS01840	COG3187	Heat shock protein
IN878_RS01845	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IN878_RS01850	COG2911	Protein conserved in bacteria
IN878_RS01860	COG3784	Protein of unknown function (DUF1318)
IN878_RS01865	COG2207	Transcriptional regulator
IN878_RS01870	COG1012	belongs to the aldehyde dehydrogenase family
IN878_RS01875	COG3733	amine oxidase
IN878_RS01880	COG2030	dehydratase
IN878_RS01880	COG1012	belongs to the aldehyde dehydrogenase family
IN878_RS01885	COG3396	Phenylacetate-CoA oxygenase
IN878_RS01890	COG3460	Phenylacetate-CoA oxygenase
IN878_RS01895	COG3396	Phenylacetate-CoA oxygenase
IN878_RS01900	COG2151	metal-sulfur cluster biosynthetic enzyme
IN878_RS01905	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IN878_RS01910	COG1024	Enoyl-CoA hydratase
IN878_RS01915	COG1024	Enoyl-CoA hydratase
IN878_RS01920	COG1250	3-hydroxyacyl-CoA dehydrogenase
IN878_RS01925	COG2050	protein possibly involved in aromatic compounds catabolism
IN878_RS01930	COG0183	Belongs to the thiolase family
IN878_RS01935	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
IN878_RS01940	COG3327	negative regulation of DNA-templated transcription, initiation
IN878_RS01945	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IN878_RS01960	COG0667	Aldo Keto reductase
IN878_RS01970	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IN878_RS01975	COG4589	Belongs to the CDS family
IN878_RS01980	COG2267	carboxylic ester hydrolase activity
IN878_RS01985	COG2453	phosphatase
IN878_RS01985	COG0671	phosphoesterase, PA-phosphatase related
IN878_RS01995	COG1643	Atp-dependent helicase
IN878_RS02000	COG1434	Gram-negative-bacterium-type cell wall biogenesis
IN878_RS02005	COG1012	belongs to the aldehyde dehydrogenase family
IN878_RS02015	COG3038	cytochrome b561
IN878_RS02030	COG0840	transmembrane signaling receptor activity
IN878_RS02035	COG0583	DNA-binding transcription factor activity
IN878_RS02040	COG5383	Protein conserved in bacteria
IN878_RS02050	COG2841	Protein conserved in bacteria
IN878_RS02055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IN878_RS02060	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IN878_RS02065	COG1275	C4-dicarboxylate transporter malic acid transport protein
IN878_RS02070	COG0500	methyltransferase
IN878_RS02085	COG0675	Transposase, IS605 OrfB family
IN878_RS02090	COG3135	benzoate transporter
IN878_RS02095	COG1396	sequence-specific DNA binding
IN878_RS02100	COG0826	peptidase U32
IN878_RS02110	COG1724	mRNA binding
IN878_RS02310	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IN878_RS02330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IN878_RS02335	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IN878_RS02340	COG3842	ATPase activity
IN878_RS02345	COG1176	ABC-type spermidine putrescine transport system, permease component I
IN878_RS02350	COG1177	transmembrane transport
IN878_RS02375	COG3238	Protein conserved in bacteria
IN878_RS02380	COG1247	-acetyltransferase
IN878_RS02385	COG2130	NADP-dependent
IN878_RS02390	COG1802	Transcriptional regulator
IN878_RS02395	COG4772	TonB-dependent receptor
IN878_RS02400	COG3391	amine dehydrogenase activity
IN878_RS02405	COG1113	amino acid transport
IN878_RS02410	COG0625	glutathione transferase activity
IN878_RS02445	COG5433	transposase activity
IN878_RS02455	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IN878_RS02460	COG2162	N-hydroxyarylamine O-acetyltransferase activity
IN878_RS02465	COG0384	phenazine biosynthesis protein PhzF
IN878_RS02470	COG2181	nitrate reductase activity
IN878_RS02475	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
IN878_RS02480	COG1140	nitrate reductase beta subunit
IN878_RS02485	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IN878_RS02490	COG2223	nitrite transmembrane transporter activity
IN878_RS02500	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IN878_RS02505	COG0697	spore germination
IN878_RS02515	COG0437	4 iron, 4 sulfur cluster binding
IN878_RS02520	COG2864	formate dehydrogenase
IN878_RS02525	COG3093	addiction module antidote protein HigA
IN878_RS02530	COG1064	alcohol dehydrogenase
IN878_RS02550	COG1764	response to oxidative stress
IN878_RS02555	COG4608	Belongs to the ABC transporter superfamily
IN878_RS02560	COG0444	Belongs to the ABC transporter superfamily
IN878_RS02565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IN878_RS02570	COG0601	transmembrane transport
IN878_RS02575	COG0747	negative chemotaxis
IN878_RS02580	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
IN878_RS02585	COG2202	Pas domain
IN878_RS02585	COG2200	EAL domain
IN878_RS02585	COG2199	diguanylate cyclase activity
IN878_RS02590	COG3706	GGDEF domain
IN878_RS02600	COG1649	PFAM Uncharacterised BCR, COG1649
IN878_RS02605	COG0531	amino acid
IN878_RS02610	COG0076	glutamate decarboxylase activity
IN878_RS02615	COG0612	Peptidase, M16
IN878_RS02620	COG4771	TonB-dependent receptor
IN878_RS02625	COG4178	(ABC) transporter
IN878_RS02635	COG0641	radical SAM
IN878_RS02640	COG3119	arylsulfatase activity
IN878_RS02645	COG2207	Transcriptional regulator
IN878_RS02655	COG0243	molybdopterin cofactor binding
IN878_RS02660	COG3539	Fimbrial protein
IN878_RS02665	COG3539	Fimbrial protein
IN878_RS02670	COG3539	Fimbrial protein
IN878_RS02705	COG3698	Phosphodiester glycosidase
IN878_RS02710	COG0598	Magnesium transport protein CorA
IN878_RS02725	COG3436	PFAM IS66 Orf2 family protein
IN878_RS02745	COG4372	Transposase
IN878_RS02785	COG3550	peptidyl-serine autophosphorylation
IN878_RS02790	COG1396	sequence-specific DNA binding
IN878_RS02850	COG3781	membrane
IN878_RS02870	COG2066	Belongs to the glutaminase family
IN878_RS02875	COG1012	belongs to the aldehyde dehydrogenase family
IN878_RS02880	COG0583	DNA-binding transcription factor activity
IN878_RS02900	COG1846	Transcriptional regulator
IN878_RS02905	COG4977	sequence-specific DNA binding
IN878_RS02915	COG0697	spore germination
IN878_RS02920	COG2814	Major facilitator Superfamily
IN878_RS02930	COG3706	GGDEF domain
IN878_RS02935	COG3111	PFAM Bacterial OB fold (BOF) protein
IN878_RS02940	COG1546	Belongs to the CinA family
IN878_RS02945	COG0339	signal peptide processing
IN878_RS02950	COG4221	oxidoreductase activity
IN878_RS02955	COG1802	Transcriptional regulator
IN878_RS02965	COG0246	Mannitol dehydrogenase
IN878_RS02985	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IN878_RS02990	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
IN878_RS02995	COG5301	cellulose 1,4-beta-cellobiosidase activity
IN878_RS03005	COG4220	transposase activity
IN878_RS03015	COG5562	phage envelope protein
IN878_RS03045	COG1278	Cold shock
IN878_RS03055	COG3772	lysozyme
IN878_RS03070	COG1278	Cold shock
IN878_RS03075	COG1278	Cold shock
IN878_RS03085	COG0484	heat shock protein binding
IN878_RS03090	COG1403	HNH endonuclease
IN878_RS03110	COG2026	Addiction module toxin, RelE StbE family
IN878_RS03115	COG3077	Addiction module antitoxin, RelB DinJ family
IN878_RS03130	COG2801	Transposase and inactivated derivatives
IN878_RS03160	COG2826	transposase and inactivated derivatives, IS30 family
IN878_RS03180	COG3436	PFAM IS66 Orf2 family protein
IN878_RS03185	COG4372	Transposase
IN878_RS03195	COG0582	viral genome integration into host DNA
IN878_RS03205	COG1063	alcohol dehydrogenase
IN878_RS03210	COG4948	Mandelate Racemase Muconate Lactonizing
IN878_RS03225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IN878_RS03240	COG0243	molybdopterin cofactor binding
IN878_RS03245	COG0243	molybdopterin cofactor binding
IN878_RS03250	COG0437	4 iron, 4 sulfur cluster binding
IN878_RS03255	COG3302	dmso reductase anchor subunit
IN878_RS03260	COG3381	protein complex oligomerization
IN878_RS03270	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IN878_RS03275	COG1940	carbohydrate kinase activity
IN878_RS03280	COG0583	DNA-binding transcription factor activity
IN878_RS03285	COG2814	Major facilitator Superfamily
IN878_RS03300	COG3591	Belongs to the peptidase S1B family
IN878_RS03315	COG0628	permease
IN878_RS03320	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
IN878_RS03325	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
IN878_RS03335	COG0531	amino acid
IN878_RS03345	COG3136	membrane protein required for alginate biosynthesis
IN878_RS03350	COG0745	RESPONSE REGULATOR receiver
IN878_RS03355	COG2205	protein histidine kinase activity
IN878_RS03365	COG0114	fumarate hydratase activity
IN878_RS03370	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IN878_RS03370	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IN878_RS03375	COG1482	cell wall glycoprotein biosynthetic process
IN878_RS03380	COG5339	Protein conserved in bacteria
IN878_RS03395	COG3250	beta-galactosidase activity
IN878_RS03400	COG1309	transcriptional regulator
IN878_RS03405	COG1028	Short-chain dehydrogenase reductase Sdr
IN878_RS03410	COG1609	Transcriptional regulator
IN878_RS03415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IN878_RS03415	COG1263	PTS System
IN878_RS03420	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
IN878_RS03430	COG0673	inositol 2-dehydrogenase activity
IN878_RS03470	COG4659	FMN binding
IN878_RS03480	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IN878_RS03485	COG3104	oligopeptide transport
IN878_RS03490	COG0625	glutathione transferase activity
IN878_RS03495	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
IN878_RS03510	COG3895	Periplasmic Protein
IN878_RS03520	COG3133	Outer membrane lipoprotein
IN878_RS03535	COG1566	PFAM secretion protein HlyD family protein
IN878_RS03540	COG1289	transmembrane transporter activity
IN878_RS03545	COG2032	superoxide dismutase activity
IN878_RS03550	COG4989	oxidoreductase activity
IN878_RS03555	COG3313	Fe-S protein
IN878_RS03560	COG1309	transcriptional regulator
IN878_RS03565	COG1902	pentaerythritol trinitrate reductase activity
IN878_RS03570	COG0346	lactoylglutathione lyase activity
IN878_RS03575	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IN878_RS03580	COG1201	RNA secondary structure unwinding
IN878_RS03585	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IN878_RS03590	COG0791	NLP P60 protein
IN878_RS03595	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IN878_RS03600	COG2814	Major facilitator Superfamily
IN878_RS03615	COG0583	DNA-binding transcription factor activity
IN878_RS03620	COG2814	Major facilitator Superfamily
IN878_RS03625	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IN878_RS03630	COG0307	riboflavin synthase, alpha
IN878_RS03640	COG3468	outer membrane autotransporter barrel domain protein
IN878_RS03660	COG4529	Protein conserved in bacteria
IN878_RS03670	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
IN878_RS03675	COG0437	4 iron, 4 sulfur cluster binding
IN878_RS03685	COG2414	aldehyde ferredoxin oxidoreductase
IN878_RS03690	COG0437	4 iron, 4 sulfur cluster binding
IN878_RS03700	COG0469	pyruvate kinase activity
IN878_RS03705	COG4238	major outer membrane lipoprotein
IN878_RS03710	COG1376	ErfK ybiS ycfS ynhG family protein
IN878_RS03725	COG0719	Fe-S assembly protein
IN878_RS03730	COG0396	ATPase activity
IN878_RS03735	COG0719	Fe-S assembly protein
IN878_RS03740	COG0316	Belongs to the HesB IscA family
IN878_RS03750	COG2050	protein possibly involved in aromatic compounds catabolism
IN878_RS03755	COG0277	FAD linked oxidase domain protein
IN878_RS03755	COG0247	lactate metabolic process
IN878_RS03760	COG0628	permease
IN878_RS03775	COG0738	Major facilitator superfamily
IN878_RS03780	COG2271	Major facilitator Superfamily
IN878_RS03795	COG4670	ketone body catabolic process
IN878_RS03800	COG1960	acyl-CoA dehydrogenase activity
IN878_RS03805	COG2207	Transcriptional regulator
IN878_RS03805	COG1917	Cupin 2, conserved barrel domain protein
IN878_RS03810	COG2086	electron transfer activity
IN878_RS03815	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
IN878_RS03820	COG0644	oxidoreductase
IN878_RS03825	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IN878_RS03830	COG0318	PFAM AMP-dependent synthetase and ligase
IN878_RS03835	COG0574	Belongs to the PEP-utilizing enzyme family
IN878_RS03835	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IN878_RS03845	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IN878_RS03850	COG4256	Hemin uptake protein
IN878_RS03865	COG0791	NLP P60 protein
IN878_RS03875	COG0386	Belongs to the glutathione peroxidase family
IN878_RS03890	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IN878_RS03890	COG0072	phenylalanine-tRNA ligase activity
IN878_RS03935	COG3137	Salt-induced outer membrane protein
IN878_RS03940	COG1105	Belongs to the carbohydrate kinase PfkB family
IN878_RS03950	COG3001	Fructosamine kinase
IN878_RS03960	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IN878_RS03965	COG1988	membrane-bound metal-dependent
IN878_RS03970	COG1823	symporter activity
IN878_RS03985	COG0753	catalase activity
IN878_RS03995	COG1486	melibiose metabolic process
IN878_RS04000	COG2169	Transcriptional regulator
IN878_RS04000	COG1917	Cupin 2, conserved barrel domain protein
IN878_RS04005	COG1447	Phosphotransferase system cellobiose-specific component IIA
IN878_RS04010	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IN878_RS04015	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IN878_RS04020	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IN878_RS04030	COG0322	excinuclease ABC activity
IN878_RS04040	COG3678	ATP-independent chaperone mediated protein folding
IN878_RS04070	COG0708	Exodeoxyribonuclease III
IN878_RS04075	COG0398	Pfam SNARE associated Golgi protein
IN878_RS04085	COG0398	Pfam SNARE associated Golgi protein
IN878_RS04090	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IN878_RS04095	COG4134	Bacterial extracellular solute-binding protein
IN878_RS04100	COG4135	transport system, permease component
IN878_RS04105	COG4136	ATPase activity
IN878_RS04110	COG2897	thiosulfate sulfurtransferase activity
IN878_RS04115	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IN878_RS04120	COG0494	nUDIX hydrolase
IN878_RS04130	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IN878_RS04140	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IN878_RS04150	COG0778	Nitroreductase
IN878_RS04155	COG0616	signal peptide processing
IN878_RS04160	COG0252	asparaginase activity
IN878_RS04165	COG1335	isochorismatase
IN878_RS04170	COG2814	Major facilitator Superfamily
IN878_RS04175	COG1349	DNA-binding transcription factor activity
IN878_RS04180	COG0667	Aldo Keto reductase
IN878_RS04185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IN878_RS04190	COG0191	fructose-bisphosphate aldolase activity
IN878_RS04195	COG1063	alcohol dehydrogenase
IN878_RS04200	COG2271	Major facilitator Superfamily
IN878_RS04205	COG1063	alcohol dehydrogenase
IN878_RS04210	COG3139	Protein of unknown function (DUF1315)
IN878_RS04220	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IN878_RS04225	COG0676	glucose-6-phosphate 1-epimerase activity
IN878_RS04230	COG0656	L-ascorbic acid biosynthetic process
IN878_RS04235	COG3713	MltA-interacting MipA family protein
IN878_RS04240	COG2766	serine protein kinase
IN878_RS04250	COG2199	diguanylate cyclase activity
IN878_RS04255	COG2199	diguanylate cyclase activity
IN878_RS04260	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IN878_RS04275	COG2207	Transcriptional regulator
IN878_RS04280	COG2807	transmembrane transport
IN878_RS04285	COG3189	MarR family transcriptional regulator
IN878_RS04290	COG3042	response to heat
IN878_RS04295	COG2203	Gaf domain
IN878_RS04295	COG2199	diguanylate cyclase activity
IN878_RS04310	COG2261	transglycosylase associated protein
IN878_RS04320	COG3615	Tellurite resistance protein tehB
IN878_RS04330	COG0583	DNA-binding transcription factor activity
IN878_RS04335	COG0473	3-isopropylmalate dehydrogenase activity
IN878_RS04345	COG4638	Rieske (2fe-2S)
IN878_RS04350	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IN878_RS04355	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
IN878_RS04360	COG0318	PFAM AMP-dependent synthetase and ligase
IN878_RS04365	COG3065	identical protein binding
IN878_RS04370	COG1214	PFAM Peptidase M22, glycoprotease
IN878_RS04375	COG1199	ATP-dependent helicase activity
IN878_RS04380	COG0251	oxidation-reduction process
IN878_RS04395	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IN878_RS04405	COG1760	l-serine dehydratase
IN878_RS04410	COG2200	EAL domain
IN878_RS04415	COG1253	flavin adenine dinucleotide binding
IN878_RS04420	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
IN878_RS04420	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IN878_RS04425	COG3715	PTS system
IN878_RS04430	COG3716	PTS system mannose fructose sorbose family IID component
IN878_RS04445	COG2226	methyltransferase
IN878_RS04475	COG1414	Transcriptional regulator
IN878_RS04480	COG2814	Major facilitator Superfamily
IN878_RS04490	COG0793	Belongs to the peptidase S41A family
IN878_RS04500	COG1956	GAF domain-containing protein
IN878_RS04505	COG2995	paraquat-inducible protein a
IN878_RS04510	COG3008	intermembrane lipid transfer
IN878_RS04530	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IN878_RS04540	COG1276	copper resistance
IN878_RS04545	COG2372	response to copper ion
IN878_RS04555	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IN878_RS04560	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IN878_RS04565	COG1770	oligopeptidase
IN878_RS04570	COG2979	Protein of unknown function (DUF533)
IN878_RS04580	COG3141	response to X-ray
IN878_RS04590	COG0800	Aldolase
IN878_RS04595	COG0129	dihydroxy-acid dehydratase activity
IN878_RS04600	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IN878_RS04605	COG1737	Transcriptional regulator
IN878_RS04610	COG0469	pyruvate kinase activity
IN878_RS04615	COG1560	Kdo2-lipid A biosynthetic process
IN878_RS04620	COG0739	heme binding
IN878_RS04625	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
IN878_RS04635	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IN878_RS04665	COG0217	transcriptional regulatory protein
IN878_RS04670	COG0494	nUDIX hydrolase
IN878_RS04680	COG1335	isochorismatase
IN878_RS04685	COG1801	Protein of unknown function DUF72
IN878_RS04690	COG3788	relative of glutathione S-transferase, MAPEG superfamily
IN878_RS04710	COG3005	denitrification pathway
IN878_RS04720	COG3102	Protein conserved in bacteria
IN878_RS04740	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IN878_RS04745	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IN878_RS04750	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
IN878_RS04755	COG0745	RESPONSE REGULATOR receiver
IN878_RS04760	COG2201	protein-glutamate methylesterase activity
IN878_RS04765	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IN878_RS04770	COG0840	transmembrane signaling receptor activity
IN878_RS04775	COG0840	transmembrane signaling receptor activity
IN878_RS04780	COG0835	chemotaxis
IN878_RS04785	COG0643	Histidine kinase
IN878_RS04785	COG2198	Histidine kinase
IN878_RS04790	COG1360	Flagellar Motor Protein
IN878_RS04795	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IN878_RS04810	COG0589	response to stress
IN878_RS04820	COG1877	trehalose-phosphatase activity
IN878_RS04825	COG1172	Belongs to the binding-protein-dependent transport system permease family
IN878_RS04830	COG1129	ABC transporter
IN878_RS04835	COG1879	ABC-type sugar transport system periplasmic component
IN878_RS04840	COG1528	Iron-storage protein
IN878_RS04860	COG1528	Iron-storage protein
IN878_RS04870	COG0814	amino acid
IN878_RS04875	COG3012	SEC-C Motif Domain Protein
IN878_RS04875	COG3318	Belongs to the UPF0149 family
IN878_RS04905	COG2197	response regulator
IN878_RS04920	COG2197	response regulator
IN878_RS04925	COG1126	abc transporter atp-binding protein
IN878_RS04930	COG0765	amino acid transport
IN878_RS04940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IN878_RS04950	COG1191	sigma factor activity
IN878_RS04965	COG1516	flagellar protein fliS
IN878_RS04975	COG0366	Alpha amylase catalytic
IN878_RS04985	COG2391	methyltransferase activity
IN878_RS04990	COG0425	Belongs to the sulfur carrier protein TusA family
IN878_RS04995	COG2135	peptidase activity
IN878_RS05010	COG2207	Transcriptional regulator
IN878_RS05015	COG1881	PFAM PEBP family protein
IN878_RS05020	COG2076	Multidrug Resistance protein
IN878_RS05030	COG1766	The M ring may be actively involved in energy transduction
IN878_RS05035	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IN878_RS05040	COG1317	bacterial-type flagellum organization
IN878_RS05045	COG1157	protein secretion by the type III secretion system
IN878_RS05050	COG2882	bacterial-type flagellum organization
IN878_RS05055	COG3144	bacterial-type flagellum assembly
IN878_RS05060	COG1580	Controls the rotational direction of flagella during chemotaxis
IN878_RS05065	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IN878_RS05070	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IN878_RS05075	COG3190	flagellar
IN878_RS05080	COG1338	Plays a role in the flagellum-specific transport system
IN878_RS05085	COG1987	bacterial-type flagellum assembly
IN878_RS05090	COG1684	flagellar biosynthetic protein fliR
IN878_RS05095	COG2197	response regulator
IN878_RS05120	COG5475	Uncharacterized small protein (DUF2158)
IN878_RS05125	COG2354	Protein conserved in bacteria
IN878_RS05130	COG0697	spore germination
IN878_RS05135	COG3727	T/G mismatch-specific endonuclease activity
IN878_RS05140	COG0270	DNA (cytosine-5-)-methyltransferase activity
IN878_RS05165	COG2826	transposase and inactivated derivatives, IS30 family
IN878_RS05180	COG2205	protein histidine kinase activity
IN878_RS05185	COG0745	RESPONSE REGULATOR receiver
IN878_RS05190	COG2351	hydroxyisourate hydrolase activity
IN878_RS05205	COG3443	Belongs to the bacterial solute-binding protein 9 family
IN878_RS05210	COG3038	cytochrome b561
IN878_RS05240	COG0477	Major facilitator Superfamily
IN878_RS05245	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IN878_RS05250	COG0217	transcriptional regulatory protein
IN878_RS05260	COG0534	Mate efflux family protein
IN878_RS05270	COG0583	DNA-binding transcription factor activity
IN878_RS05275	COG0583	DNA-binding transcription factor activity
IN878_RS05285	COG1376	ErfK ybiS ycfS ynhG family protein
IN878_RS05300	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
IN878_RS05310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IN878_RS05330	COG1735	metal-dependent hydrolase with the TIM-barrel fold
IN878_RS05390	COG2003	Belongs to the UPF0758 family
IN878_RS05420	COG4372	Transposase
IN878_RS05445	COG1686	Belongs to the peptidase S11 family
IN878_RS05450	COG2925	Exonuclease
IN878_RS05455	COG0425	Belongs to the sulfur carrier protein TusA family
IN878_RS05465	COG0531	amino acid
IN878_RS05475	COG0583	DNA-binding transcription factor activity
IN878_RS05480	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IN878_RS05485	COG4115	mRNA cleavage
IN878_RS05490	COG2161	toxin-antitoxin pair type II binding
IN878_RS05520	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IN878_RS05540	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
IN878_RS05545	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IN878_RS05550	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IN878_RS05570	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IN878_RS05575	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
IN878_RS05605	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IN878_RS05615	COG0438	transferase activity, transferring glycosyl groups
IN878_RS05620	COG2327	Polysaccharide pyruvyl transferase
IN878_RS05625	COG2244	polysaccharide biosynthetic process
IN878_RS05630	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IN878_RS05635	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IN878_RS05640	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
IN878_RS05640	COG0662	Cupin 2, conserved barrel domain protein
IN878_RS05645	COG0297	glycogen (starch) synthase activity
IN878_RS05650	COG1051	belongs to the nudix hydrolase family
IN878_RS05655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IN878_RS05660	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
IN878_RS05665	COG0110	maltose O-acetyltransferase activity
IN878_RS05670	COG1216	Glycosyl transferase, family 2
IN878_RS05680	COG0438	transferase activity, transferring glycosyl groups
IN878_RS05685	COG1045	serine acetyltransferase
IN878_RS05690	COG0463	Glycosyl transferase, family 2
IN878_RS05695	COG3206	protein involved in exopolysaccharide biosynthesis
IN878_RS05695	COG0489	protein tyrosine kinase activity
IN878_RS05700	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IN878_RS05705	COG1596	polysaccharide export
IN878_RS05715	COG1253	flavin adenine dinucleotide binding
IN878_RS05720	COG2982	Protein involved in outer membrane biogenesis
IN878_RS05730	COG0572	uridine kinase
IN878_RS05735	COG5002	protein histidine kinase activity
IN878_RS05735	COG5001	Diguanylate cyclase
IN878_RS05735	COG3447	MASE1 domain protein
IN878_RS05740	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IN878_RS05745	COG0443	Heat shock 70 kDa protein
IN878_RS05750	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
IN878_RS05755	COG3779	Protein conserved in bacteria
IN878_RS05760	COG0631	protein serine/threonine phosphatase activity
IN878_RS05765	COG4245	von Willebrand factor, type A
IN878_RS05805	COG2205	protein histidine kinase activity
IN878_RS05810	COG0745	RESPONSE REGULATOR receiver
IN878_RS05820	COG3609	addiction module antidote protein, CC2985 family
IN878_RS05830	COG0826	peptidase U32
IN878_RS05885	COG5301	cellulose 1,4-beta-cellobiosidase activity
IN878_RS05980	COG4695	Portal protein
IN878_RS06045	COG4974	Belongs to the 'phage' integrase family
IN878_RS06065	COG1063	alcohol dehydrogenase
IN878_RS06070	COG3775	system Galactitol-specific IIC component
IN878_RS06075	COG3414	Phosphotransferase system galactitol-specific IIB component
IN878_RS06080	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IN878_RS06095	COG1830	Aldolase
IN878_RS06100	COG2211	Major facilitator Superfamily
IN878_RS06105	COG1397	ADP-ribosylglycohydrolase
IN878_RS06110	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IN878_RS06115	COG2188	Transcriptional regulator
IN878_RS06120	COG3757	hydrolase, family 25
IN878_RS06125	COG0351	phosphomethylpyrimidine kinase
IN878_RS06145	COG5455	response to cobalt ion
IN878_RS06150	COG3539	Fimbrial protein
IN878_RS06155	COG3188	usher protein
IN878_RS06160	COG3121	Chaperone
IN878_RS06165	COG3539	Fimbrial protein
IN878_RS06175	COG0489	protein tyrosine kinase activity
IN878_RS06185	COG3831	ATPase activity
IN878_RS06190	COG3831	ATPase activity
IN878_RS06200	COG0714	Associated with various cellular activities
IN878_RS06205	COG2425	protein containing a von Willebrand factor type A (vWA) domain
IN878_RS06210	COG3552	Protein containing von Willebrand factor type A (VWA) domain
IN878_RS06215	COG4715	Zinc finger, swim domain protein
IN878_RS06220	COG4808	Protein conserved in bacteria
IN878_RS06225	COG4807	Protein conserved in bacteria
IN878_RS06230	COG3279	Response regulator of the LytR AlgR family
IN878_RS06235	COG3275	phosphorelay sensor kinase activity
IN878_RS06240	COG0789	Transcriptional regulator
IN878_RS06250	COG1174	glycine betaine transport
IN878_RS06255	COG1125	glycine betaine transport
IN878_RS06260	COG1174	glycine betaine transport
IN878_RS06265	COG1732	Glycine betaine
IN878_RS06270	COG1472	Belongs to the glycosyl hydrolase 3 family
IN878_RS06275	COG0277	FAD linked oxidase domain protein
IN878_RS06280	COG1686	Belongs to the peptidase S11 family
IN878_RS06290	COG0586	Pfam SNARE associated Golgi protein
IN878_RS06295	COG1028	Short-chain dehydrogenase reductase Sdr
IN878_RS06310	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IN878_RS06320	COG1346	cytolysis
IN878_RS06330	COG2949	membrane
IN878_RS06340	COG0493	'glutamate synthase
IN878_RS06345	COG0167	dihydroorotate dehydrogenase activity
IN878_RS06345	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IN878_RS06350	COG4211	Belongs to the binding-protein-dependent transport system permease family
IN878_RS06355	COG1129	ABC transporter
IN878_RS06360	COG1879	ABC-type sugar transport system periplasmic component
IN878_RS06365	COG1609	Transcriptional regulator
IN878_RS06370	COG2311	Membrane
IN878_RS06385	COG4771	TonB-dependent receptor
IN878_RS06390	COG0833	amino acid
IN878_RS06395	COG0583	DNA-binding transcription factor activity
IN878_RS06400	COG2855	membrane
IN878_RS06410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IN878_RS06410	COG1522	sequence-specific DNA binding
IN878_RS06415	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IN878_RS06425	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IN878_RS06430	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IN878_RS06435	COG2313	pseudouridylate synthase activity
IN878_RS06440	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IN878_RS06445	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IN878_RS06445	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IN878_RS06445	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IN878_RS06450	COG1105	Belongs to the carbohydrate kinase PfkB family
IN878_RS06455	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IN878_RS06455	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IN878_RS06460	COG2814	Major facilitator Superfamily
IN878_RS06475	COG0246	Mannitol dehydrogenase
IN878_RS06480	COG0523	cobalamin synthesis protein
IN878_RS06485	COG0671	phosphoesterase, PA-phosphatase related
IN878_RS06490	COG0791	NLP P60 protein
IN878_RS06495	COG2200	EAL domain
IN878_RS06500	COG4166	transmembrane transport
IN878_RS06505	COG4174	ABC transporter (Permease)
IN878_RS06510	COG4239	(ABC) transporter, permease
IN878_RS06515	COG4172	Belongs to the ABC transporter superfamily
IN878_RS06525	COG2814	Major facilitator Superfamily
IN878_RS06530	COG1187	pseudouridine synthase activity
IN878_RS06535	COG1061	Type III restriction enzyme res subunit
IN878_RS06555	COG3083	sulfuric ester hydrolase activity
IN878_RS06565	COG3468	outer membrane autotransporter barrel domain protein
IN878_RS06570	COG2197	response regulator
IN878_RS06575	COG4235	cytochrome complex assembly
IN878_RS06575	COG3088	subunit of a heme lyase
IN878_RS06580	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IN878_RS06585	COG1138	Cytochrome C-type biogenesis protein
IN878_RS06595	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IN878_RS06600	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IN878_RS06605	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IN878_RS06610	COG4133	protoheme IX ABC transporter activity
IN878_RS06615	COG3005	denitrification pathway
IN878_RS06620	COG3043	anaerobic respiration
IN878_RS06625	COG0348	domain, Protein
IN878_RS06630	COG0437	4 iron, 4 sulfur cluster binding
IN878_RS06640	COG3062	negative regulation of establishment of protein localization
IN878_RS06645	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IN878_RS06645	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
IN878_RS06665	COG4615	Cyclic peptide transporter
IN878_RS06670	COG3145	DNA-N1-methyladenine dioxygenase activity
IN878_RS06675	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IN878_RS06675	COG2169	Transcriptional regulator
IN878_RS06680	COG1477	protein flavinylation
IN878_RS06685	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IN878_RS06690	COG2198	Histidine kinase
IN878_RS06690	COG0642	Histidine kinase
IN878_RS06695	COG2197	response regulator
IN878_RS06700	COG2205	protein histidine kinase activity
IN878_RS06700	COG0784	Response regulator, receiver
IN878_RS06705	COG3852	Histidine kinase
IN878_RS06710	COG2204	response regulator
IN878_RS06715	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IN878_RS06720	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IN878_RS06725	COG2031	fatty acid transporter
IN878_RS06730	COG0183	Belongs to the thiolase family
IN878_RS06735	COG4676	Protein conserved in bacteria
IN878_RS06740	COG5445	Predicted secreted protein (DUF2300)
IN878_RS06745	COG2373	Large extracellular alpha-helical protein
IN878_RS06750	COG3234	Protein of unknown function (DUF1175)
IN878_RS06755	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
IN878_RS06760	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IN878_RS06770	COG3468	outer membrane autotransporter barrel domain protein
IN878_RS06775	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IN878_RS06780	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IN878_RS06785	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IN878_RS06790	COG3642	lipopolysaccharide core region biosynthetic process
IN878_RS06800	COG0584	glycerophosphoryl diester phosphodiesterase
IN878_RS06805	COG2271	Major facilitator Superfamily
IN878_RS06810	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IN878_RS06820	COG0247	lactate metabolic process
IN878_RS06825	COG5464	transposase or invertase
IN878_RS06840	COG2271	Major facilitator Superfamily
IN878_RS06850	COG1414	Transcriptional regulator
IN878_RS06915	COG0318	PFAM AMP-dependent synthetase and ligase
IN878_RS06925	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IN878_RS06940	COG1169	isochorismate synthase
IN878_RS06945	COG4575	ribosome binding
IN878_RS06950	COG2153	protein acetylation
IN878_RS06960	COG5160	protein modification by small protein removal
IN878_RS06965	COG2304	oxidoreductase activity
IN878_RS06970	COG2234	aminopeptidase activity
IN878_RS06990	COG0457	Tetratricopeptide repeat
IN878_RS07000	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IN878_RS07005	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IN878_RS07015	COG0839	Belongs to the complex I subunit 6 family
IN878_RS07030	COG1034	ATP synthesis coupled electron transport
IN878_RS07035	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IN878_RS07040	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
IN878_RS07060	COG0583	DNA-binding transcription factor activity
IN878_RS07065	COG0436	Aminotransferase
IN878_RS07075	COG0490	domain, Protein
IN878_RS07075	COG0471	metal ion transport
IN878_RS07080	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IN878_RS07095	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IN878_RS07100	COG0280	phosphate acetyltransferase
IN878_RS07100	COG0857	belongs to the CobB CobQ family
IN878_RS07105	COG1288	antiporter activity
IN878_RS07110	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
IN878_RS07115	COG0622	Phosphoesterase
IN878_RS07120	COG0625	glutathione transferase activity
IN878_RS07125	COG0625	glutathione transferase activity
IN878_RS07130	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IN878_RS07135	COG1090	epimerase
IN878_RS07140	COG5464	transposase or invertase
IN878_RS07145	COG4598	ABC transporter
IN878_RS07150	COG4160	amino acid transport
IN878_RS07155	COG4215	(ABC) transporter
IN878_RS07160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IN878_RS07165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IN878_RS07170	COG0163	prenyltransferase activity
IN878_RS07175	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IN878_RS07180	COG1286	toxin biosynthetic process
IN878_RS07185	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
IN878_RS07190	COG0285	dihydrofolate synthase activity
IN878_RS07200	COG0586	Pfam SNARE associated Golgi protein
IN878_RS07210	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IN878_RS07225	COG2814	Major facilitator Superfamily
IN878_RS07230	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IN878_RS07245	COG3101	peptidyl-lysine hydroxylation
IN878_RS07250	COG0730	response to heat
IN878_RS07265	COG2890	protein-(glutamine-N5) methyltransferase activity
IN878_RS07280	COG3539	Fimbrial protein
IN878_RS07285	COG3539	Fimbrial protein
IN878_RS07290	COG3539	Fimbrial protein
IN878_RS07295	COG3121	Chaperone
IN878_RS07300	COG3188	usher protein
IN878_RS07305	COG3539	Fimbrial protein
IN878_RS07310	COG2062	phosphohistidine phosphatase, SixA
IN878_RS07325	COG3691	Protein conserved in bacteria
IN878_RS07330	COG2067	long-chain fatty acid transport protein
IN878_RS07340	COG2853	Lipoprotein
IN878_RS07345	COG2116	formate transmembrane transporter activity
IN878_RS07355	COG0583	DNA-binding transcription factor activity
IN878_RS07360	COG2610	gluconate transmembrane transporter activity
IN878_RS07370	COG0477	Major facilitator Superfamily
IN878_RS07375	COG1566	PFAM secretion protein HlyD family protein
IN878_RS07380	COG2197	response regulator
IN878_RS07385	COG0784	Response regulator, receiver
IN878_RS07385	COG2205	protein histidine kinase activity
IN878_RS07385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IN878_RS07385	COG2198	Histidine kinase
IN878_RS07390	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IN878_RS07395	COG0679	Auxin Efflux Carrier
IN878_RS07400	COG0028	Belongs to the TPP enzyme family
IN878_RS07425	COG1560	Kdo2-lipid A biosynthetic process
IN878_RS07435	COG0436	Aminotransferase
IN878_RS07440	COG3275	phosphorelay sensor kinase activity
IN878_RS07445	COG3279	Response regulator of the LytR AlgR family
IN878_RS07450	COG2207	Transcriptional regulator
IN878_RS07455	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IN878_RS07455	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IN878_RS07455	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IN878_RS07460	COG1363	Peptidase, m42
IN878_RS07465	COG0006	proline dipeptidase activity
IN878_RS07470	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IN878_RS07475	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IN878_RS07500	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IN878_RS07505	COG2199	diguanylate cyclase activity
IN878_RS07505	COG2200	EAL domain
IN878_RS07520	COG3415	Transposase
IN878_RS07525	COG3415	Transposase
IN878_RS07560	COG0583	DNA-binding transcription factor activity
IN878_RS07570	COG2211	Major facilitator Superfamily
IN878_RS07575	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IN878_RS07585	COG0583	DNA-binding transcription factor activity
IN878_RS07590	COG0385	Bile acid
IN878_RS07595	COG3530	Putative quorum-sensing-regulated virulence factor
IN878_RS07615	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IN878_RS07620	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IN878_RS07625	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IN878_RS07630	COG2190	(PTS) system
IN878_RS07645	COG3831	ATPase activity
IN878_RS07645	COG4884	unkown
IN878_RS07650	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IN878_RS07655	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IN878_RS07660	COG4208	sulfate ABC transporter
IN878_RS07665	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IN878_RS07670	COG4150	thiosulfate binding
IN878_RS07675	COG1028	Short-chain dehydrogenase reductase Sdr
IN878_RS07690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IN878_RS07690	COG1263	PTS System
IN878_RS07695	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IN878_RS07700	COG2837	iron assimilation
IN878_RS07715	COG0456	acetyltransferase
IN878_RS07720	COG0860	N-Acetylmuramoyl-L-alanine amidase
IN878_RS07730	COG2207	Transcriptional regulator
IN878_RS07735	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
IN878_RS07740	COG4816	utilization protein
IN878_RS07750	COG4303	Ethanolamine ammonia lyase large subunit
IN878_RS07755	COG4819	ethanolamine utilization protein
IN878_RS07760	COG3192	ethanolamine utilization protein
IN878_RS07765	COG1454	alcohol dehydrogenase
IN878_RS07785	COG1012	belongs to the aldehyde dehydrogenase family
IN878_RS07790	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
IN878_RS07795	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
IN878_RS07800	COG0280	phosphate acetyltransferase
IN878_RS07805	COG4812	Cobalamin adenosyltransferase
IN878_RS07810	COG4766	ethanolamine catabolic process
IN878_RS07815	COG4917	ethanolamine utilization protein
IN878_RS07820	COG4810	utilization protein
IN878_RS07825	COG0280	phosphate acetyltransferase
IN878_RS07825	COG0281	malic enzyme
IN878_RS07830	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IN878_RS07835	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IN878_RS07840	COG5342	invasion associated locus B
IN878_RS07850	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IN878_RS07850	COG0493	'glutamate synthase
IN878_RS07855	COG3850	Histidine kinase
IN878_RS07860	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IN878_RS07870	COG1393	Belongs to the ArsC family
IN878_RS07885	COG0400	carboxylic ester hydrolase activity
IN878_RS07890	COG1444	tRNA N-acetyltransferase activity
IN878_RS07895	COG2321	neutral zinc metallopeptidase
IN878_RS07905	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
IN878_RS07915	COG2716	regulation of RNA biosynthetic process
IN878_RS07920	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IN878_RS07925	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IN878_RS07930	COG0651	ATP synthesis coupled electron transport
IN878_RS07935	COG0650	Formate hydrogenlyase subunit 4
IN878_RS07940	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IN878_RS07945	COG4237	Hydrogenase 4 membrane
IN878_RS07950	COG0651	ATP synthesis coupled electron transport
IN878_RS07955	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
IN878_RS07955	COG3261	NADH dehydrogenase
IN878_RS07960	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IN878_RS07965	COG3260	NADH ubiquinone oxidoreductase 20
IN878_RS07975	COG3604	Transcriptional regulator
IN878_RS07980	COG2116	formate transmembrane transporter activity
IN878_RS07985	COG0628	permease
IN878_RS07990	COG4783	chaperone-mediated protein folding
IN878_RS07995	COG1393	Belongs to the ArsC family
IN878_RS08005	COG2233	PERMEase
IN878_RS08020	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IN878_RS08025	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IN878_RS08030	COG0248	Ppx GppA phosphatase
IN878_RS08035	COG2200	EAL domain
IN878_RS08070	COG0516	GMP reductase activity
IN878_RS08070	COG0517	IMP dehydrogenase activity
IN878_RS08080	COG1645	bacterial-type flagellum-dependent swarming motility
IN878_RS08095	COG2976	Protein conserved in bacteria
IN878_RS08125	COG4953	penicillin-binding protein 1C
IN878_RS08130	COG2373	Large extracellular alpha-helical protein
IN878_RS08135	COG2897	thiosulfate sulfurtransferase activity
IN878_RS08150	COG2975	iron-sulfur cluster assembly
IN878_RS08155	COG0633	Ferredoxin
IN878_RS08175	COG0822	iron-sulfur transferase activity
IN878_RS08195	COG0483	inositol monophosphate 1-phosphatase activity
IN878_RS08200	COG1073	alpha beta
IN878_RS08205	COG3711	transcriptional antiterminator
IN878_RS08210	COG2814	Major facilitator Superfamily
IN878_RS08215	COG0583	DNA-binding transcription factor activity
IN878_RS08220	COG4638	Rieske (2fe-2S)
IN878_RS08245	COG2259	Doxx family
IN878_RS08250	COG2017	converts alpha-aldose to the beta-anomer
IN878_RS08255	COG1063	alcohol dehydrogenase
IN878_RS08260	COG1172	Belongs to the binding-protein-dependent transport system permease family
IN878_RS08265	COG1129	ABC transporter
IN878_RS08270	COG1879	ABC-type sugar transport system periplasmic component
IN878_RS08290	COG1017	nitric oxide dioxygenase activity
IN878_RS08290	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IN878_RS08295	COG0347	Belongs to the P(II) protein family
IN878_RS08300	COG2204	response regulator
IN878_RS08305	COG3170	Tfp pilus assembly protein FimV
IN878_RS08310	COG2205	protein histidine kinase activity
IN878_RS08315	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IN878_RS08315	COG0047	phosphoribosylformylglycinamidine synthase activity
IN878_RS08330	COG0560	Phosphoserine phosphatase
IN878_RS08335	COG1737	Transcriptional regulator
IN878_RS08340	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IN878_RS08355	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IN878_RS08375	COG0681	Belongs to the peptidase S26 family
IN878_RS08385	COG3086	response to oxidative stress
IN878_RS08390	COG3026	antisigma factor binding
IN878_RS08395	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
IN878_RS08400	COG1595	DNA-templated transcription, initiation
IN878_RS08410	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
IN878_RS08420	COG0513	Belongs to the DEAD box helicase family
IN878_RS08425	COG0583	DNA-binding transcription factor activity
IN878_RS08445	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IN878_RS08450	COG3118	belongs to the thioredoxin family
IN878_RS08455	COG3148	PFAM DTW domain containing protein
IN878_RS08460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IN878_RS08460	COG1042	CoA-binding domain protein
IN878_RS08460	COG0045	succinate-CoA ligase (ADP-forming) activity
IN878_RS08465	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IN878_RS08470	COG5544	Lipoprotein
IN878_RS08475	COG0477	Major facilitator Superfamily
IN878_RS08500	COG0542	response to heat
IN878_RS08505	COG1496	oxidoreductase activity
IN878_RS08510	COG0564	pseudouridine synthase activity
IN878_RS08515	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IN878_RS08520	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IN878_RS08530	COG1605	Chorismate mutase
IN878_RS08530	COG0077	Prephenate dehydratase
IN878_RS08535	COG0287	Prephenate dehydrogenase
IN878_RS08535	COG1605	Chorismate mutase
IN878_RS08540	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IN878_RS08555	COG2199	diguanylate cyclase activity
IN878_RS08560	COG2885	chlorophyll binding
IN878_RS08585	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IN878_RS08590	COG4137	Cytochrome C assembly protein
IN878_RS08595	COG4536	flavin adenine dinucleotide binding
IN878_RS08610	COG0497	DNA recombination
IN878_RS08615	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IN878_RS08625	COG2867	negative regulation of translational initiation
IN878_RS08640	COG0582	viral genome integration into host DNA
IN878_RS08650	COG1475	DNA binding
IN878_RS08710	COG3468	outer membrane autotransporter barrel domain protein
IN878_RS08745	COG0579	oxidoreductase
IN878_RS08750	COG1012	belongs to the aldehyde dehydrogenase family
IN878_RS08755	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IN878_RS08760	COG1113	amino acid transport
IN878_RS08765	COG1802	Transcriptional regulator
IN878_RS08770	COG1652	LysM domain
IN878_RS08775	COG0401	homolog of Blt101
IN878_RS08780	COG0640	Transcriptional regulator
IN878_RS08785	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IN878_RS08790	COG2916	Histone family protein nucleoid-structuring protein H-NS
IN878_RS08805	COG4575	ribosome binding
IN878_RS08810	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IN878_RS08820	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IN878_RS08825	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IN878_RS08830	COG4175	Glycine betaine
IN878_RS08835	COG4176	ABC-type proline glycine betaine transport system permease component
IN878_RS08840	COG2113	Glycine betaine
IN878_RS08845	COG2814	Major facilitator Superfamily
IN878_RS08850	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IN878_RS08860	COG1846	Transcriptional regulator
IN878_RS08865	COG1566	PFAM secretion protein HlyD family protein
IN878_RS08870	COG2814	Major facilitator Superfamily
IN878_RS08885	COG1238	metal cluster binding
IN878_RS08890	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IN878_RS08925	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IN878_RS08945	COG1546	Belongs to the CinA family
IN878_RS08950	COG2951	lytic endotransglycosylase activity
IN878_RS08955	COG3730	PTS system glucitol sorbitol-specific
IN878_RS08960	COG3732	PTS system glucitol sorbitol-specific
IN878_RS08965	COG3731	PTS system glucitol sorbitol-specific IIA component
IN878_RS08970	COG1028	Short-chain dehydrogenase reductase Sdr
IN878_RS08975	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
IN878_RS08980	COG1349	DNA-binding transcription factor activity
IN878_RS08985	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IN878_RS08985	COG0517	IMP dehydrogenase activity
IN878_RS09005	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
IN878_RS09010	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IN878_RS09015	COG1609	Transcriptional regulator
IN878_RS09020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IN878_RS09020	COG1263	PTS System
IN878_RS09025	COG2723	6-phospho-beta-galactosidase activity
IN878_RS09030	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IN878_RS09040	COG3260	NADH ubiquinone oxidoreductase 20
IN878_RS09045	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IN878_RS09050	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
IN878_RS09050	COG3261	NADH dehydrogenase
IN878_RS09055	COG0650	Formate hydrogenlyase subunit 4
IN878_RS09060	COG0651	ATP synthesis coupled electron transport
IN878_RS09065	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IN878_RS09075	COG0375	protein maturation
IN878_RS09080	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IN878_RS09085	COG0298	carbon dioxide binding
IN878_RS09090	COG0409	Hydrogenase expression formation protein
IN878_RS09095	COG0309	Hydrogenase expression formation protein (HypE)
IN878_RS09100	COG3604	Transcriptional regulator
IN878_RS09120	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IN878_RS09125	COG1349	DNA-binding transcription factor activity
IN878_RS09130	COG2084	Dehydrogenase
IN878_RS09135	COG3395	kinase activity
IN878_RS09140	COG0235	Class ii aldolase
IN878_RS09145	COG3622	Belongs to the hyi family
IN878_RS09150	COG2610	gluconate transmembrane transporter activity
IN878_RS09155	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IN878_RS09160	COG4942	peptidase
IN878_RS09160	COG1388	LysM domain
IN878_RS09215	COG2234	aminopeptidase activity
IN878_RS09230	COG1203	CRISPR-associated helicase, Cas3
IN878_RS09235	COG3385	transposase activity
IN878_RS09250	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IN878_RS09260	COG0720	synthase
IN878_RS09265	COG0644	oxidoreductase
IN878_RS09270	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IN878_RS09275	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
IN878_RS09280	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
IN878_RS09285	COG2086	electron transfer activity
IN878_RS09290	COG0477	Major facilitator Superfamily
IN878_RS09295	COG0277	FAD linked oxidase domain protein
IN878_RS09300	COG1028	Short-chain dehydrogenase reductase Sdr
IN878_RS09305	COG2223	nitrite transmembrane transporter activity
IN878_RS09310	COG1070	Carbohydrate kinase
IN878_RS09320	COG0602	queuosine metabolic process
IN878_RS09330	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IN878_RS09345	COG3956	TIGRFAM MazG family protein
IN878_RS09350	COG2337	Toxic component of a toxin-antitoxin (TA) module
IN878_RS09355	COG2336	PFAM SpoVT AbrB
IN878_RS09360	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IN878_RS09365	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IN878_RS09370	COG3850	Histidine kinase
IN878_RS09370	COG3437	response regulator, receiver
IN878_RS09370	COG4999	Histidine kinase
IN878_RS09370	COG2205	protein histidine kinase activity
IN878_RS09375	COG4948	Mandelate Racemase Muconate Lactonizing
IN878_RS09380	COG4948	Mandelate Racemase Muconate Lactonizing
IN878_RS09385	COG2271	Major facilitator Superfamily
IN878_RS09390	COG0716	FMN binding
IN878_RS09395	COG0564	pseudouridine synthase activity
IN878_RS09400	COG3098	single-species biofilm formation
IN878_RS09415	COG1611	Belongs to the LOG family
IN878_RS09420	COG0814	amino acid
IN878_RS09425	COG1760	l-serine dehydratase
IN878_RS09435	COG1454	alcohol dehydrogenase
IN878_RS09440	COG0235	Class ii aldolase
IN878_RS09445	COG0738	Major facilitator superfamily
IN878_RS09455	COG1070	Carbohydrate kinase
IN878_RS09465	COG1349	DNA-binding transcription factor activity
IN878_RS09475	COG2363	Small membrane protein
IN878_RS09480	COG0583	DNA-binding transcription factor activity
IN878_RS09490	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IN878_RS09495	COG2166	iron-sulfur cluster assembly
IN878_RS09500	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IN878_RS09505	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
IN878_RS09525	COG0860	N-Acetylmuramoyl-L-alanine amidase
IN878_RS09530	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IN878_RS09530	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IN878_RS09535	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IN878_RS09540	COG1074	ATP-dependent DNA helicase activity
IN878_RS09545	COG1025	Belongs to the peptidase M16 family
IN878_RS09550	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IN878_RS09555	COG4967	type IV pilus modification protein PilV
IN878_RS09565	COG4795	General secretion pathway protein
IN878_RS09570	COG2165	general secretion pathway protein
IN878_RS09585	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
IN878_RS09600	COG0861	Integral membrane protein TerC family
IN878_RS09610	COG0667	Aldo Keto reductase
IN878_RS09625	COG1609	Transcriptional regulator
IN878_RS09635	COG0583	DNA-binding transcription factor activity
IN878_RS09640	COG1794	racemase activity, acting on amino acids and derivatives
IN878_RS09645	COG2814	Major facilitator Superfamily
IN878_RS09650	COG1028	Short-chain dehydrogenase reductase Sdr
IN878_RS09660	COG0183	Belongs to the thiolase family
IN878_RS09665	COG0814	amino acid
IN878_RS09670	COG2771	luxR family
IN878_RS09675	COG3710	Transcriptional regulator
IN878_RS09700	COG0457	Tetratricopeptide repeat
IN878_RS09815	COG4942	peptidase
IN878_RS09820	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IN878_RS09825	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
IN878_RS09830	COG2080	2 iron, 2 sulfur cluster binding
IN878_RS09835	COG3829	transcription factor binding
IN878_RS09840	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IN878_RS09845	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IN878_RS09850	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IN878_RS09860	COG0549	Belongs to the carbamate kinase family
IN878_RS09865	COG3608	succinylglutamate desuccinylase aspartoacylase
IN878_RS09865	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IN878_RS09870	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IN878_RS09875	COG2068	MobA-Related Protein
IN878_RS09880	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IN878_RS09880	COG0493	'glutamate synthase
IN878_RS09885	COG0402	S-adenosylhomocysteine deaminase activity
IN878_RS09890	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
IN878_RS09895	COG2080	2 iron, 2 sulfur cluster binding
IN878_RS09895	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IN878_RS09900	COG2233	PERMEase
IN878_RS09905	COG0402	S-adenosylhomocysteine deaminase activity
IN878_RS09910	COG2252	PERMEase
IN878_RS09915	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IN878_RS09920	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IN878_RS09920	COG0493	'glutamate synthase
IN878_RS09925	COG2233	PERMEase
IN878_RS09945	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IN878_RS09955	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IN878_RS09960	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IN878_RS09965	COG4974	Belongs to the 'phage' integrase family
IN878_RS09970	COG0716	FMN binding
IN878_RS09980	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IN878_RS09990	COG1272	protein, Hemolysin III
IN878_RS10000	COG2723	6-phospho-beta-galactosidase activity
IN878_RS10005	COG1028	Short-chain dehydrogenase reductase Sdr
IN878_RS10030	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IN878_RS10035	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IN878_RS10040	COG0006	proline dipeptidase activity
IN878_RS10060	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IN878_RS10070	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IN878_RS10090	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IN878_RS10090	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IN878_RS10095	COG1703	isobutyryl-CoA mutase activity
IN878_RS10100	COG1024	Enoyl-CoA hydratase
IN878_RS10105	COG0427	acetyl-CoA hydrolase
IN878_RS10110	COG0583	DNA-binding transcription factor activity
IN878_RS10115	COG2968	Membrane
IN878_RS10120	COG1279	arginine transmembrane transporter activity
IN878_RS10125	COG0668	transmembrane transport
IN878_RS10130	COG0191	fructose-bisphosphate aldolase activity
IN878_RS10145	COG1072	(Pantothenic acid kinase))
IN878_RS10150	COG3722	fumarate hydratase activity
IN878_RS10155	COG1494	fructose-1,6-bisphosphatase
IN878_RS10160	COG1063	alcohol dehydrogenase
IN878_RS10165	COG2213	PTS system mannitol-specific
IN878_RS10170	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IN878_RS10175	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IN878_RS10180	COG0501	Belongs to the peptidase M48B family
IN878_RS10190	COG1166	arginine decarboxylase activity
IN878_RS10210	COG2814	Major facilitator Superfamily
IN878_RS10220	COG2356	endonuclease I
IN878_RS10225	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IN878_RS10230	COG0189	ligase activity
IN878_RS10245	COG2805	Type II/IV secretion system protein
IN878_RS10250	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IN878_RS10255	COG0762	integral membrane protein
IN878_RS10265	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IN878_RS10270	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IN878_RS10280	COG0252	asparaginase activity
IN878_RS10290	COG3171	Protein conserved in bacteria
IN878_RS10300	COG1194	a g-specific adenine glycosylase
IN878_RS10315	COG2211	Major facilitator Superfamily
IN878_RS10320	COG1982	Orn Lys Arg decarboxylase major
IN878_RS10325	COG1811	Na channel or pump
IN878_RS10335	COG0582	viral genome integration into host DNA
IN878_RS10430	COG2271	Major facilitator Superfamily
IN878_RS10445	COG0625	glutathione transferase activity
IN878_RS10450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IN878_RS10495	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
IN878_RS10500	COG0306	phosphate transporter
IN878_RS10505	COG0754	glutathionylspermidine amidase activity
IN878_RS10510	COG0625	glutathione transferase activity
IN878_RS10515	COG0298	carbon dioxide binding
IN878_RS10525	COG1773	rubredoxin
IN878_RS10530	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IN878_RS10535	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
IN878_RS10540	COG5557	Pfam Polysulphide reductase, NrfD
IN878_RS10545	COG0437	4 iron, 4 sulfur cluster binding
IN878_RS10550	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
IN878_RS10565	COG0667	Aldo Keto reductase
IN878_RS10575	COG1028	Short-chain dehydrogenase reductase Sdr
IN878_RS10580	COG0848	biopolymer transport protein
IN878_RS10585	COG0811	peptide transport
IN878_RS10590	COG0626	cystathionine gamma-synthase activity
IN878_RS10595	COG0586	Pfam SNARE associated Golgi protein
IN878_RS10600	COG2207	Transcriptional regulator
IN878_RS10605	COG1979	alcohol dehydrogenase
IN878_RS10610	COG0656	L-ascorbic acid biosynthetic process
IN878_RS10620	COG4238	major outer membrane lipoprotein
IN878_RS10625	COG1032	radical SAM domain protein
IN878_RS10630	COG2132	Multicopper oxidase
IN878_RS10635	COG0204	Acyl-transferase
IN878_RS10640	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IN878_RS10645	COG4166	transmembrane transport
IN878_RS10650	COG2944	sequence-specific DNA binding
IN878_RS10660	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
IN878_RS10665	COG3111	PFAM Bacterial OB fold (BOF) protein
IN878_RS10670	COG0745	RESPONSE REGULATOR receiver
IN878_RS10675	COG0642	Histidine kinase
IN878_RS10685	COG2249	NAD(P)H dehydrogenase (quinone) activity
IN878_RS10690	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IN878_RS10695	COG0187	DNA topoisomerase II activity
IN878_RS10700	COG3150	esterase
IN878_RS10705	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IN878_RS10710	COG3151	Protein conserved in bacteria
IN878_RS10715	COG0494	nUDIX hydrolase
IN878_RS10720	COG1538	Outer membrane efflux protein
IN878_RS10730	COG0754	glutathionylspermidine amidase activity
IN878_RS10735	COG3384	dioxygenase
IN878_RS10755	COG2960	long-chain fatty acid transporting porin activity
IN878_RS10760	COG3539	Fimbrial protein
IN878_RS10765	COG3188	usher protein
IN878_RS10770	COG3121	Chaperone
IN878_RS10775	COG3539	Fimbrial protein
IN878_RS10785	COG1585	Membrane protein implicated in regulation of membrane protease activity
IN878_RS10790	COG2268	Band 7 protein
IN878_RS10815	COG3025	triphosphatase activity
IN878_RS10820	COG4991	sh3 domain protein
IN878_RS10835	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IN878_RS10845	COG0583	DNA-binding transcription factor activity
IN878_RS10850	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IN878_RS10855	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IN878_RS10860	COG0471	metal ion transport
IN878_RS10870	COG0828	Belongs to the bacterial ribosomal protein bS21 family
IN878_RS10875	COG0358	DNA primase activity
IN878_RS10880	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IN878_RS10895	COG2375	cellular response to nickel ion
IN878_RS10900	COG1695	Transcriptional regulator
IN878_RS10905	COG0840	transmembrane signaling receptor activity
IN878_RS10915	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IN878_RS10920	COG1609	Transcriptional regulator
IN878_RS10925	COG3250	beta-galactosidase activity
IN878_RS10930	COG2731	YhcH YjgK YiaL family protein
IN878_RS10935	COG0531	amino acid
IN878_RS10945	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
IN878_RS10945	COG3408	Glycogen debranching enzyme
IN878_RS10950	COG1902	pentaerythritol trinitrate reductase activity
IN878_RS10950	COG0446	pyridine nucleotide-disulphide oxidoreductase
IN878_RS10955	COG5499	transcription regulator containing HTH domain
IN878_RS10960	COG4680	protein conserved in bacteria
IN878_RS10970	COG1451	nucleotide metabolic process
IN878_RS10975	COG2949	membrane
IN878_RS10980	COG0673	inositol 2-dehydrogenase activity
IN878_RS10985	COG0861	Integral membrane protein TerC family
IN878_RS10990	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
IN878_RS11000	COG2721	sulfolactate sulfo-lyase activity
IN878_RS11010	COG2271	Major facilitator Superfamily
IN878_RS11015	COG2186	Transcriptional regulator
IN878_RS11020	COG0586	Pfam SNARE associated Golgi protein
IN878_RS11030	COG1422	Protein of unknown function (DUF1090)
IN878_RS11035	COG4575	ribosome binding
IN878_RS11040	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
IN878_RS11050	COG2259	Doxx family
IN878_RS11055	COG0435	Glutathione S-transferase
IN878_RS11060	COG3152	Membrane
IN878_RS11065	COG3152	Membrane
IN878_RS11070	COG0583	DNA-binding transcription factor activity
IN878_RS11075	COG1741	Belongs to the pirin family
IN878_RS11090	COG0814	amino acid
IN878_RS11095	COG1760	l-serine dehydratase
IN878_RS11100	COG0251	oxidation-reduction process
IN878_RS11105	COG1882	Formate acetyltransferase
IN878_RS11110	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IN878_RS11120	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IN878_RS11125	COG0583	DNA-binding transcription factor activity
IN878_RS11150	COG1929	Belongs to the glycerate kinase type-1 family
IN878_RS11155	COG2084	Dehydrogenase
IN878_RS11165	COG2271	Major facilitator Superfamily
IN878_RS11185	COG2002	toxin-antitoxin pair type II binding
IN878_RS11195	COG1349	DNA-binding transcription factor activity
IN878_RS11205	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IN878_RS11215	COG3716	PTS system mannose fructose sorbose family IID component
IN878_RS11220	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
IN878_RS11225	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IN878_RS11230	COG2222	sugar isomerase
IN878_RS11240	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IN878_RS11245	COG3715	PTS system
IN878_RS11255	COG0363	glucosamine-6-phosphate deaminase activity
IN878_RS11260	COG3539	Fimbrial protein
IN878_RS11265	COG3121	Chaperone
IN878_RS11275	COG3539	Fimbrial protein
IN878_RS11280	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IN878_RS11285	COG3107	peptidoglycan biosynthetic process
IN878_RS11300	COG2823	Periplasmic or secreted lipoprotein
IN878_RS11305	COG0701	Predicted permease
IN878_RS11310	COG0702	epimerase
IN878_RS11315	COG0693	protein deglycase activity
IN878_RS11330	COG3153	acetyltransferase
IN878_RS11335	COG3154	lipid carrier protein
IN878_RS11340	COG0826	peptidase U32
IN878_RS11345	COG0826	peptidase U32
IN878_RS11350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IN878_RS11355	COG0814	amino acid
IN878_RS11360	COG0513	Belongs to the DEAD box helicase family
IN878_RS11400	COG0195	Participates in both transcription termination and antitermination
IN878_RS11420	COG2194	sulfuric ester hydrolase activity
IN878_RS11430	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IN878_RS11440	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IN878_RS11445	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IN878_RS11455	COG1534	Rna-binding protein
IN878_RS11460	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IN878_RS11465	COG2027	D-alanyl-D-alanine carboxypeptidase
IN878_RS11475	COG0697	spore germination
IN878_RS11490	COG0142	geranyltranstransferase activity
IN878_RS11495	COG3423	Transcriptional regulator
IN878_RS11505	COG5007	Belongs to the BolA IbaG family
IN878_RS11510	COG3113	response to antibiotic
IN878_RS11515	COG2854	intermembrane phospholipid transfer
IN878_RS11520	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IN878_RS11525	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IN878_RS11530	COG1127	ABC transporter
IN878_RS11535	COG0530	calcium, potassium:sodium antiporter activity
IN878_RS11540	COG0517	IMP dehydrogenase activity
IN878_RS11540	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IN878_RS11545	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IN878_RS11550	COG3117	lipopolysaccharide transmembrane transporter activity
IN878_RS11555	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IN878_RS11560	COG1137	ATPase activity
IN878_RS11565	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
IN878_RS11570	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IN878_RS11585	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IN878_RS11590	COG0515	serine threonine protein kinase
IN878_RS11600	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
IN878_RS11605	COG5002	protein histidine kinase activity
IN878_RS11605	COG2198	Histidine kinase
IN878_RS11605	COG0784	Response regulator, receiver
IN878_RS11610	COG1242	4 iron, 4 sulfur cluster binding
IN878_RS11615	COG0069	glutamate synthase activity
IN878_RS11615	COG0067	glutamate synthase
IN878_RS11615	COG0070	glutamate synthase
IN878_RS11620	COG0493	'glutamate synthase
IN878_RS11625	COG3539	Fimbrial protein
IN878_RS11630	COG3121	Chaperone
IN878_RS11635	COG3188	usher protein
IN878_RS11645	COG3539	Fimbrial protein
IN878_RS11650	COG4804	nuclease activity
IN878_RS11655	COG2731	YhcH YjgK YiaL family protein
IN878_RS11685	COG3069	C4-dicarboxylate transmembrane transporter activity
IN878_RS11690	COG2969	positive regulation of protein catabolic process
IN878_RS11695	COG0625	glutathione transferase activity
IN878_RS11710	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IN878_RS11715	COG3105	Protein conserved in bacteria
IN878_RS11720	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IN878_RS11725	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IN878_RS11745	COG2732	(Barnase) inhibitor
IN878_RS11765	COG0583	DNA-binding transcription factor activity
IN878_RS11770	COG0312	modulator of DNA gyrase
IN878_RS11775	COG3164	Protein of unknown function
IN878_RS11780	COG1530	ribonuclease E activity
IN878_RS11785	COG0424	maF-like protein
IN878_RS11790	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IN878_RS11795	COG1792	Involved in formation and maintenance of cell shape
IN878_RS11800	COG1077	Cell shape determining protein MreB Mrl
IN878_RS11805	COG2200	EAL domain
IN878_RS11805	COG2199	diguanylate cyclase activity
IN878_RS11810	COG0604	alcohol dehydrogenase
IN878_RS11815	COG0511	ligase activity, forming carbon-carbon bonds
IN878_RS11820	COG0439	Biotin carboxylase
IN878_RS11825	COG3924	membrane
IN878_RS11830	COG4145	pantothenate transmembrane transporter activity
IN878_RS11840	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IN878_RS11850	COG2189	Belongs to the N(4) N(6)-methyltransferase family
IN878_RS11860	COG1309	transcriptional regulator
IN878_RS11865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IN878_RS11870	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IN878_RS11880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IN878_RS11885	COG4597	amino acid ABC transporter
IN878_RS11890	COG0765	amino acid transport
IN878_RS11895	COG1126	abc transporter atp-binding protein
IN878_RS11935	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IN878_RS11955	COG0551	DNA topoisomerase type I activity
IN878_RS11965	COG0758	DNA mediated transformation
IN878_RS11985	COG0569	domain protein
IN878_RS11995	COG3036	rescue of stalled ribosome
IN878_RS12000	COG0789	Transcriptional regulator
IN878_RS12040	COG0201	protein transport
IN878_RS12130	COG0089	rRNA binding
IN878_RS12155	COG3409	Peptidoglycan-binding domain 1 protein
IN878_RS12155	COG3267	Type II secretory pathway component ExeA
IN878_RS12160	COG3031	protein transport across the cell outer membrane
IN878_RS12165	COG1450	Type ii and iii secretion system protein
IN878_RS12170	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IN878_RS12175	COG1459	type II secretion system
IN878_RS12180	COG2165	general secretion pathway protein
IN878_RS12185	COG2165	general secretion pathway protein
IN878_RS12190	COG2165	general secretion pathway protein
IN878_RS12195	COG4795	General secretion pathway protein
IN878_RS12200	COG3156	type II secretion system protein K
IN878_RS12205	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
IN878_RS12210	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
IN878_RS12215	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
IN878_RS12220	COG2193	ferroxidase activity
IN878_RS12225	COG2906	2 iron, 2 sulfur cluster binding
IN878_RS12230	COG3979	chitinase
IN878_RS12270	COG2964	Protein conserved in bacteria
IN878_RS12275	COG0545	Peptidyl-prolyl cis-trans isomerase
IN878_RS12285	COG1047	Peptidyl-prolyl cis-trans
IN878_RS12290	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
IN878_RS12305	COG0488	(ABC) transporter
IN878_RS12310	COG0429	hydrolase of the alpha beta-hydrolase fold
IN878_RS12320	COG3954	Phosphoribulokinase
IN878_RS12325	COG1765	OsmC-like protein
IN878_RS12330	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IN878_RS12335	COG1289	transmembrane transporter activity
IN878_RS12340	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IN878_RS12345	COG0512	Glutamine amidotransferase of anthranilate synthase
IN878_RS12350	COG2184	nucleotidyltransferase activity
IN878_RS12360	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IN878_RS12370	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IN878_RS12375	COG2146	nitrite reductase [NAD(P)H] activity
IN878_RS12380	COG2116	formate transmembrane transporter activity
IN878_RS12395	COG0531	amino acid
IN878_RS12400	COG2222	sugar isomerase
IN878_RS12405	COG1082	Xylose isomerase domain protein TIM barrel
IN878_RS12410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IN878_RS12415	COG2188	Transcriptional regulator
IN878_RS12420	COG0626	cystathionine gamma-synthase activity
IN878_RS12435	COG1735	metal-dependent hydrolase with the TIM-barrel fold
IN878_RS12440	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
IN878_RS12445	COG3457	Alanine racemase
IN878_RS12455	COG2188	Transcriptional regulator
IN878_RS12460	COG0180	Tryptophanyl-tRNA synthetase
IN878_RS12465	COG0546	phosphoglycolate phosphatase activity
IN878_RS12470	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IN878_RS12475	COG0338	D12 class N6 adenine-specific DNA methyltransferase
IN878_RS12480	COG3266	domain, Protein
IN878_RS12495	COG4796	Type ii and iii secretion system protein
IN878_RS12510	COG3166	PFAM Fimbrial assembly family protein
IN878_RS12515	COG4972	Pilus assembly protein
IN878_RS12520	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IN878_RS12525	COG0494	nUDIX hydrolase
IN878_RS12535	COG1011	Hydrolase
IN878_RS12540	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IN878_RS12550	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
IN878_RS12570	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IN878_RS12575	COG2183	response to ionizing radiation
IN878_RS12580	COG1918	ferrous iron import across plasma membrane
IN878_RS12585	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
IN878_RS12595	COG5464	transposase or invertase
IN878_RS12605	COG1040	competence protein
IN878_RS12615	COG2610	gluconate transmembrane transporter activity
IN878_RS12620	COG1640	4-alpha-glucanotransferase
IN878_RS12625	COG0058	SHG alpha-glucan phosphorylase activity
IN878_RS12640	COG1690	Belongs to the RtcB family
IN878_RS12645	COG4650	regulator
IN878_RS12650	COG1349	DNA-binding transcription factor activity
IN878_RS12665	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IN878_RS12675	COG0058	SHG alpha-glucan phosphorylase activity
IN878_RS12700	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IN878_RS12705	COG2095	MarC family integral membrane protein
IN878_RS12710	COG2610	gluconate transmembrane transporter activity
IN878_RS12715	COG3265	gluconokinase activity
IN878_RS12720	COG1609	Transcriptional regulator
IN878_RS12725	COG1741	Belongs to the pirin family
IN878_RS12730	COG0673	inositol 2-dehydrogenase activity
IN878_RS12735	COG1247	-acetyltransferase
IN878_RS12740	COG3157	Type VI secretion system effector, Hcp
IN878_RS12760	COG0405	Gamma-glutamyltransferase
IN878_RS12770	COG0584	glycerophosphoryl diester phosphodiesterase
IN878_RS12775	COG3842	ATPase activity
IN878_RS12780	COG0395	ABC-type sugar transport system, permease component
IN878_RS12785	COG1175	transmembrane transport
IN878_RS12790	COG1653	transport
IN878_RS12795	COG0410	ABC transporter
IN878_RS12800	COG0411	ABC transporter
IN878_RS12805	COG4177	L-phenylalanine transmembrane transporter activity
IN878_RS12810	COG0559	Belongs to the binding-protein-dependent transport system permease family
IN878_RS12815	COG0683	leucine binding
IN878_RS12820	COG0456	acetyltransferase
IN878_RS12825	COG0683	leucine binding
IN878_RS12830	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IN878_RS12835	COG2177	Part of the ABC transporter FtsEX involved in
IN878_RS12840	COG2884	Cell division ATP-binding protein ftsE
IN878_RS12845	COG0552	protein localization to endoplasmic reticulum
IN878_RS12850	COG0742	ribosomal rna small subunit methyltransferase
IN878_RS12855	COG3776	membrane
IN878_RS12865	COG3714	YhhN family
IN878_RS12870	COG2217	Heavy metal translocating P-type atpase
IN878_RS12880	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IN878_RS12890	COG0477	Major facilitator Superfamily
IN878_RS12895	COG0628	permease
IN878_RS12900	COG2091	lysine biosynthetic process via aminoadipic acid
IN878_RS12905	COG0747	negative chemotaxis
IN878_RS12910	COG0601	transmembrane transport
IN878_RS12915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IN878_RS12920	COG0444	Belongs to the ABC transporter superfamily
IN878_RS12925	COG1124	(ABC) transporter
IN878_RS12935	COG3209	COG3209 Rhs family protein
IN878_RS12950	COG5433	transposase activity
IN878_RS12955	COG0842	Transport permease protein
IN878_RS12960	COG1129	ABC transporter
IN878_RS12960	COG0842	Transport permease protein
IN878_RS12965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IN878_RS13000	COG3436	PFAM IS66 Orf2 family protein
IN878_RS13015	COG0745	RESPONSE REGULATOR receiver
IN878_RS13020	COG1276	copper resistance
IN878_RS13025	COG2372	response to copper ion
IN878_RS13030	COG3667	copper resistance
IN878_RS13035	COG2132	Multicopper oxidase
IN878_RS13055	COG3436	PFAM IS66 Orf2 family protein
IN878_RS13060	COG4372	Transposase
IN878_RS13065	COG0739	heme binding
IN878_RS13095	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IN878_RS13165	COG2081	HI0933 family
IN878_RS13170	COG0306	phosphate transporter
IN878_RS13180	COG0589	response to stress
IN878_RS13185	COG3104	oligopeptide transport
IN878_RS13195	COG0339	signal peptide processing
IN878_RS13200	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IN878_RS13205	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IN878_RS13215	COG0640	Transcriptional regulator
IN878_RS13220	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IN878_RS13225	COG1393	Belongs to the ArsC family
IN878_RS13235	COG3065	identical protein binding
IN878_RS13240	COG2197	response regulator
IN878_RS13245	COG1285	pathogenesis
IN878_RS13260	COG3247	response to pH
IN878_RS13265	COG2771	luxR family
IN878_RS13275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IN878_RS13280	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IN878_RS13285	COG2207	Transcriptional regulator
IN878_RS13290	COG2207	Transcriptional regulator
IN878_RS13295	COG0076	glutamate decarboxylase activity
IN878_RS13300	COG1858	cytochrome C peroxidase
IN878_RS13310	COG2197	response regulator
IN878_RS13315	COG0583	DNA-binding transcription factor activity
IN878_RS13320	COG1295	ribonuclease BN
IN878_RS13325	COG0477	Major facilitator Superfamily
IN878_RS13330	COG2982	Protein involved in outer membrane biogenesis
IN878_RS13335	COG2200	EAL domain
IN878_RS13340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IN878_RS13345	COG0612	Peptidase, M16
IN878_RS13355	COG2200	EAL domain
IN878_RS13355	COG2199	diguanylate cyclase activity
IN878_RS13360	COG0457	Tetratricopeptide repeat
IN878_RS13360	COG3118	belongs to the thioredoxin family
IN878_RS13365	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
IN878_RS13370	COG1215	transferase activity, transferring glycosyl groups
IN878_RS13375	COG1215	transferase activity, transferring glycosyl groups
IN878_RS13400	COG2194	sulfuric ester hydrolase activity
IN878_RS13410	COG0814	amino acid
IN878_RS13415	COG4608	Belongs to the ABC transporter superfamily
IN878_RS13420	COG0444	Belongs to the ABC transporter superfamily
IN878_RS13425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IN878_RS13430	COG0601	transmembrane transport
IN878_RS13435	COG0747	negative chemotaxis
IN878_RS13445	COG2194	sulfuric ester hydrolase activity
IN878_RS13450	COG2223	nitrite transmembrane transporter activity
IN878_RS13455	COG5571	outer membrane autotransporter
IN878_RS13460	COG2818	Glycosylase
IN878_RS13465	COG0456	acetyltransferase
IN878_RS13470	COG0243	molybdopterin cofactor binding
IN878_RS13475	COG2885	chlorophyll binding
IN878_RS13490	COG2944	sequence-specific DNA binding
IN878_RS13495	COG1278	Cold shock
IN878_RS13525	COG3274	enterobacterial common antigen metabolic process
IN878_RS13530	COG4682	membrane
IN878_RS13535	COG4682	membrane
IN878_RS13540	COG1070	Carbohydrate kinase
IN878_RS13550	COG4213	ABC transporter substrate-binding protein
IN878_RS13555	COG1129	ABC transporter
IN878_RS13560	COG4214	carbohydrate transport
IN878_RS13565	COG2207	Transcriptional regulator
IN878_RS13565	COG1609	Transcriptional regulator
IN878_RS13570	COG2992	FlgJ-related protein
IN878_RS13575	COG0366	Alpha amylase catalytic
IN878_RS13580	COG3977	Valine--pyruvate aminotransferase
IN878_RS13585	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IN878_RS13590	COG1414	Transcriptional regulator
IN878_RS13600	COG2731	YhcH YjgK YiaL family protein
IN878_RS13605	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IN878_RS13610	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IN878_RS13615	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IN878_RS13620	COG1070	Carbohydrate kinase
IN878_RS13625	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
IN878_RS13630	COG3623	hexulose-6-phosphate isomerase
IN878_RS13635	COG0235	Class ii aldolase
IN878_RS13650	COG3713	MltA-interacting MipA family protein
IN878_RS13655	COG0583	DNA-binding transcription factor activity
IN878_RS13660	COG1566	PFAM secretion protein HlyD family protein
IN878_RS13675	COG1012	belongs to the aldehyde dehydrogenase family
IN878_RS13680	COG1454	alcohol dehydrogenase
IN878_RS13685	COG3276	selenocysteine insertion sequence binding
IN878_RS13695	COG0625	glutathione transferase activity
IN878_RS13700	COG3209	COG3209 Rhs family protein
IN878_RS13705	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
IN878_RS13715	COG1566	PFAM secretion protein HlyD family protein
IN878_RS13725	COG2213	PTS system mannitol-specific
IN878_RS13725	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IN878_RS13735	COG3722	fumarate hydratase activity
IN878_RS13750	COG1620	l-lactate permease
IN878_RS13755	COG2186	Transcriptional regulator
IN878_RS13765	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IN878_RS13770	COG1045	serine acetyltransferase
IN878_RS13785	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IN878_RS13790	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IN878_RS13800	COG4942	peptidase
IN878_RS13805	COG2861	carbohydrate metabolic process
IN878_RS13810	COG1216	Glycosyl transferase, family 2
IN878_RS13820	COG0156	8-amino-7-oxononanoate synthase activity
IN878_RS13830	COG0859	PFAM glycosyl transferase family 9
IN878_RS13835	COG0859	PFAM glycosyl transferase family 9
IN878_RS13855	COG3642	lipopolysaccharide core region biosynthetic process
IN878_RS13860	COG1442	glycosyl transferase family 8
IN878_RS13865	COG1442	glycosyl transferase family 8
IN878_RS13870	COG0438	transferase activity, transferring glycosyl groups
IN878_RS13875	COG1442	glycosyl transferase family 8
IN878_RS13880	COG0515	serine threonine protein kinase
IN878_RS13885	COG0438	transferase activity, transferring glycosyl groups
IN878_RS13890	COG0859	PFAM glycosyl transferase family 9
IN878_RS13895	COG1519	Transferase
IN878_RS13925	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IN878_RS13950	COG1561	YicC-like family, N-terminal region
IN878_RS13955	COG3645	SOS response
IN878_RS13960	COG2860	membrane
IN878_RS13970	COG0194	GDP metabolic process
IN878_RS13980	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IN878_RS13985	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IN878_RS13990	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IN878_RS13995	COG0786	glutamate:sodium symporter activity
IN878_RS14000	COG2233	PERMEase
IN878_RS14005	COG2982	Protein involved in outer membrane biogenesis
IN878_RS14010	COG1501	Belongs to the glycosyl hydrolase 31 family
IN878_RS14015	COG2211	Major facilitator Superfamily
IN878_RS14025	COG2814	Major facilitator Superfamily
IN878_RS14030	COG0697	spore germination
IN878_RS14035	COG1464	Belongs to the NlpA lipoprotein family
IN878_RS14055	COG2252	PERMEase
IN878_RS14065	COG2271	Major facilitator Superfamily
IN878_RS14070	COG2271	Major facilitator Superfamily
IN878_RS14075	COG3851	Histidine kinase
IN878_RS14080	COG2197	response regulator
IN878_RS14085	COG0440	acetolactate synthase activity
IN878_RS14090	COG0028	Belongs to the TPP enzyme family
IN878_RS14105	COG2814	Major facilitator Superfamily
IN878_RS14110	COG0641	radical SAM
IN878_RS14120	COG2149	membrane
IN878_RS14140	COG2207	Transcriptional regulator
IN878_RS14155	COG2188	Transcriptional regulator
IN878_RS14175	COG5645	(Lipo)protein
IN878_RS14180	COG0823	Involved in the tonB-independent uptake of proteins
IN878_RS14185	COG0644	oxidoreductase
IN878_RS14190	COG2271	Major facilitator Superfamily
IN878_RS14200	COG0800	Aldolase
IN878_RS14205	COG3734	2-keto-3-deoxy-galactonokinase
IN878_RS14210	COG2186	Transcriptional regulator
IN878_RS14220	COG0561	phosphatase activity
IN878_RS14225	COG3753	Protein conserved in bacteria
IN878_RS14230	COG0187	DNA topoisomerase II activity
IN878_RS14240	COG0592	DNA-directed DNA polymerase activity
IN878_RS14290	COG0814	amino acid
IN878_RS14305	COG2091	lysine biosynthetic process via aminoadipic acid
IN878_RS14310	COG0431	NADPH-dependent FMN reductase
IN878_RS14315	COG2252	PERMEase
IN878_RS14320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IN878_RS14330	COG3196	Protein conserved in bacteria
IN878_RS14335	COG0363	glucosamine-6-phosphate deaminase activity
IN878_RS14340	COG2382	esterase
IN878_RS14350	COG2723	6-phospho-beta-galactosidase activity
IN878_RS14355	COG2190	(PTS) system
IN878_RS14355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IN878_RS14355	COG1263	PTS System
IN878_RS14360	COG3711	transcriptional antiterminator
IN878_RS14365	COG0704	Plays a role in the regulation of phosphate uptake
IN878_RS14370	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IN878_RS14375	COG0581	inorganic phosphate transmembrane transporter activity
IN878_RS14380	COG0573	inorganic phosphate transmembrane transporter activity
IN878_RS14385	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IN878_RS14390	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IN878_RS14440	COG3312	ion transport
IN878_RS14455	COG0716	FMN binding
IN878_RS14460	COG1522	sequence-specific DNA binding
IN878_RS14490	COG1129	ABC transporter
IN878_RS14495	COG1172	Belongs to the binding-protein-dependent transport system permease family
IN878_RS14500	COG1879	ABC-type sugar transport system periplasmic component
IN878_RS14505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IN878_RS14510	COG1609	Transcriptional regulator
IN878_RS14515	COG0477	Major facilitator Superfamily
IN878_RS14520	COG2186	Transcriptional regulator
IN878_RS14560	COG3085	chromosome segregation
IN878_RS14565	COG0606	chelatase, subunit chli
IN878_RS14585	COG3978	acetolactate synthase activity
IN878_RS14590	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IN878_RS14600	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IN878_RS14605	COG0583	DNA-binding transcription factor activity
IN878_RS14615	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IN878_RS14625	COG0210	DNA helicase
IN878_RS14640	COG3118	belongs to the thioredoxin family
IN878_RS14650	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IN878_RS14655	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IN878_RS14660	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
IN878_RS14665	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IN878_RS14670	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IN878_RS14675	COG1088	dTDP-glucose 4,6-dehydratase activity
IN878_RS14680	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IN878_RS14685	COG0456	acetyltransferase
IN878_RS14690	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IN878_RS14695	COG2244	polysaccharide biosynthetic process
IN878_RS14715	COG1113	amino acid transport
IN878_RS14740	COG0641	radical SAM
IN878_RS14745	COG3119	arylsulfatase activity
IN878_RS14750	COG3071	HemY protein
IN878_RS14755	COG2959	enzyme of heme biosynthesis
IN878_RS14760	COG1587	Uroporphyrinogen-III synthase
IN878_RS14770	COG3072	Adenylate cyclase
IN878_RS14780	COG5567	small periplasmic lipoprotein
IN878_RS14790	COG3159	Protein conserved in bacteria
IN878_RS14800	COG1011	Hydrolase
IN878_RS14805	COG0210	DNA helicase
IN878_RS14810	COG3698	Phosphodiester glycosidase
IN878_RS14815	COG0598	Magnesium transport protein CorA
IN878_RS14830	COG2962	Rard protein
IN878_RS14835	COG2050	protein possibly involved in aromatic compounds catabolism
IN878_RS14840	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
IN878_RS14845	COG0514	ATP-dependent DNA helicase (RecQ)
IN878_RS14850	COG1280	lysine exporter protein (LysE YggA)
IN878_RS14855	COG1280	lysine exporter protein (LysE YggA)
IN878_RS14860	COG2267	carboxylic ester hydrolase activity
IN878_RS14865	COG0561	phosphatase activity
IN878_RS14870	COG0697	spore germination
IN878_RS14875	COG0583	DNA-binding transcription factor activity
IN878_RS14885	COG0412	Dienelactone hydrolase
IN878_RS14890	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
IN878_RS14895	COG1322	Protein conserved in bacteria
IN878_RS14905	COG3165	ubiquinone biosynthetic process from chorismate
IN878_RS14915	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IN878_RS14920	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IN878_RS14925	COG0805	protein transport
IN878_RS14930	COG0084	hydrolase, TatD family'
IN878_RS14935	COG0250	Participates in transcription elongation, termination and antitermination
IN878_RS14940	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IN878_RS14945	COG0543	2 iron, 2 sulfur cluster binding
IN878_RS14950	COG0183	Belongs to the thiolase family
IN878_RS14965	COG1739	Uncharacterized protein family UPF0029
IN878_RS14970	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IN878_RS14975	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
IN878_RS15005	COG1763	Mo-molybdopterin cofactor biosynthetic process
IN878_RS15010	COG0746	molybdenum cofactor guanylyltransferase activity
IN878_RS15015	COG3084	Protein conserved in bacteria
IN878_RS15020	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IN878_RS15025	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IN878_RS15030	COG5339	Protein conserved in bacteria
IN878_RS15035	COG0204	Acyl-transferase
IN878_RS15040	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IN878_RS15040	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IN878_RS15055	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IN878_RS15065	COG2204	response regulator
IN878_RS15070	COG3852	Histidine kinase
IN878_RS15075	COG0174	glutamine synthetase
IN878_RS15080	COG1217	gtp-binding protein TYPA
IN878_RS15085	COG2188	Transcriptional regulator
IN878_RS15090	COG1082	Xylose isomerase domain protein TIM barrel
IN878_RS15095	COG2271	Major facilitator Superfamily
IN878_RS15100	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
IN878_RS15105	COG2211	Major facilitator Superfamily
IN878_RS15110	COG2211	Major facilitator Superfamily
IN878_RS15115	COG1501	Belongs to the glycosyl hydrolase 31 family
IN878_RS15120	COG2017	converts alpha-aldose to the beta-anomer
IN878_RS15125	COG2942	2-epimerase
IN878_RS15130	COG3684	Belongs to the aldolase LacD family
IN878_RS15135	COG2084	Dehydrogenase
IN878_RS15140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IN878_RS15145	COG1349	DNA-binding transcription factor activity
IN878_RS15150	COG1011	Hydrolase
IN878_RS15165	COG0456	acetyltransferase
IN878_RS15170	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IN878_RS15175	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IN878_RS15185	COG2864	formate dehydrogenase
IN878_RS15190	COG0437	4 iron, 4 sulfur cluster binding
IN878_RS15210	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IN878_RS15210	COG3711	transcriptional antiterminator
IN878_RS15215	COG1363	Peptidase, m42
IN878_RS15220	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IN878_RS15220	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IN878_RS15225	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IN878_RS15265	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IN878_RS15275	COG2258	MOSC domain
IN878_RS15280	COG2205	protein histidine kinase activity
IN878_RS15285	COG0745	RESPONSE REGULATOR receiver
IN878_RS15290	COG3678	ATP-independent chaperone mediated protein folding
IN878_RS15295	COG4974	Belongs to the 'phage' integrase family
IN878_RS15340	COG2856	Zn peptidase
IN878_RS15355	COG4695	Portal protein
IN878_RS15450	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
IN878_RS15465	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IN878_RS15520	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IN878_RS15540	COG3152	Membrane
IN878_RS15545	COG3691	Protein conserved in bacteria
IN878_RS15550	COG0589	response to stress
IN878_RS15555	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IN878_RS15560	COG1494	fructose-1,6-bisphosphatase
IN878_RS15570	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IN878_RS15585	COG1575	Belongs to the MenA family. Type 1 subfamily
IN878_RS15600	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IN878_RS15605	COG1609	Transcriptional regulator
IN878_RS15610	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IN878_RS15620	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
IN878_RS15630	COG0626	cystathionine gamma-synthase activity
IN878_RS15635	COG0527	aspartate kinase activity
IN878_RS15635	COG0460	homoserine dehydrogenase
IN878_RS15640	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IN878_RS15650	COG0697	spore germination
IN878_RS15655	COG3738	Protein conserved in bacteria
IN878_RS15660	COG0371	Dehydrogenase
IN878_RS15665	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IN878_RS15670	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IN878_RS15670	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IN878_RS15670	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IN878_RS15675	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IN878_RS15680	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IN878_RS15685	COG1882	Formate acetyltransferase
IN878_RS15690	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IN878_RS15695	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IN878_RS15700	COG2207	Transcriptional regulator
IN878_RS15705	COG2194	sulfuric ester hydrolase activity
IN878_RS15720	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IN878_RS15735	COG0583	DNA-binding transcription factor activity
IN878_RS15745	COG1309	transcriptional regulator
IN878_RS15760	COG4206	TonB-dependent receptor
IN878_RS15790	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IN878_RS15795	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
IN878_RS15795	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
IN878_RS15830	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IN878_RS15835	COG0250	Participates in transcription elongation, termination and antitermination
IN878_RS15875	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IN878_RS15885	COG2104	thiamine diphosphate biosynthetic process
IN878_RS15890	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IN878_RS15925	COG3068	Protein conserved in bacteria
IN878_RS15940	COG3678	ATP-independent chaperone mediated protein folding
IN878_RS15945	COG4191	Histidine kinase
IN878_RS15950	COG2204	response regulator
IN878_RS15955	COG0151	Belongs to the GarS family
IN878_RS15990	COG0456	acetyltransferase
IN878_RS16000	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IN878_RS16005	COG2224	Isocitrate lyase
IN878_RS16020	COG1414	Transcriptional regulator
IN878_RS16025	COG0646	methionine synthase
IN878_RS16025	COG1410	methionine synthase
IN878_RS16030	COG1283	sodium-dependent phosphate transmembrane transporter activity
IN878_RS16040	COG1187	pseudouridine synthase activity
IN878_RS16050	COG0527	aspartate kinase activity
IN878_RS16075	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IN878_RS16095	COG2814	Major facilitator Superfamily
IN878_RS16095	COG0477	Major facilitator Superfamily
IN878_RS16100	COG3833	ABC-type maltose transport systems, permease component
IN878_RS16105	COG1175	transmembrane transport
IN878_RS16110	COG2182	Extracellular solute-binding protein
IN878_RS16115	COG3842	ATPase activity
IN878_RS16155	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IN878_RS16165	COG0534	Mate efflux family protein
IN878_RS16170	COG3237	CsbD-like
IN878_RS16175	COG0735	belongs to the Fur family
IN878_RS16185	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IN878_RS16195	COG0604	alcohol dehydrogenase
IN878_RS16200	COG0305	Participates in initiation and elongation during chromosome replication
IN878_RS16205	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IN878_RS16210	COG1448	Aminotransferase
IN878_RS16220	COG3700	Belongs to the class B bacterial acid phosphatase family
IN878_RS16225	COG0432	Pfam Uncharacterised protein family UPF0047
IN878_RS16230	COG2315	Protein conserved in bacteria
IN878_RS16235	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IN878_RS16240	COG0629	single-stranded DNA binding
IN878_RS16250	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IN878_RS16255	COG2207	Transcriptional regulator
IN878_RS16260	COG0789	Transcriptional regulator
IN878_RS16265	COG2252	PERMEase
IN878_RS16270	COG0025	NhaP-type Na H and K H
IN878_RS16275	COG1357	PFAM Pentapeptide repeats (8 copies)
IN878_RS16285	COG3162	membrane
IN878_RS16290	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IN878_RS16300	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
IN878_RS16305	COG0437	4 iron, 4 sulfur cluster binding
IN878_RS16310	COG3301	Polysulphide reductase, NrfD
IN878_RS16315	COG1138	Cytochrome C-type biogenesis protein
IN878_RS16320	COG3088	subunit of a heme lyase
IN878_RS16325	COG4235	cytochrome complex assembly
IN878_RS16330	COG1301	dicarboxylic acid transport
IN878_RS16335	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
IN878_RS16345	COG1538	Outer membrane efflux protein
IN878_RS16350	COG1289	transmembrane transporter activity
IN878_RS16355	COG1566	PFAM secretion protein HlyD family protein
IN878_RS16365	COG2015	COG2015, Alkyl sulfatase and related hydrolases
IN878_RS16370	COG1940	carbohydrate kinase activity
IN878_RS16375	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IN878_RS16380	COG1172	Belongs to the binding-protein-dependent transport system permease family
IN878_RS16385	COG1129	ABC transporter
IN878_RS16390	COG1879	ABC-type sugar transport system periplasmic component
IN878_RS16395	COG1737	Transcriptional regulator
IN878_RS16400	COG0698	ribose 5-phosphate isomerase
IN878_RS16410	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
IN878_RS16415	COG0456	acetyltransferase
IN878_RS16420	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
IN878_RS16425	COG3454	Phosphonate metabolism
IN878_RS16430	COG4778	phosphonate C-P lyase system protein PhnL
IN878_RS16435	COG4107	phosphonate C-P lyase system protein PhnK
IN878_RS16440	COG3627	carbon phosphorus lyase activity
IN878_RS16445	COG3626	phosphonate metabolism
IN878_RS16450	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
IN878_RS16455	COG3624	Phosphonate C-P lyase system protein PhnG
IN878_RS16460	COG2188	Transcriptional regulator
IN878_RS16470	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
IN878_RS16475	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IN878_RS16480	COG2764	glyoxalase bleomycin resistance protein dioxygenase
IN878_RS16485	COG2824	Alkylphosphonate utilization operon protein PhnA
IN878_RS16490	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
IN878_RS16500	COG0477	Major facilitator Superfamily
IN878_RS16510	COG0642	Histidine kinase
IN878_RS16515	COG0745	RESPONSE REGULATOR receiver
IN878_RS16520	COG2194	sulfuric ester hydrolase activity
IN878_RS16525	COG0531	amino acid
IN878_RS16530	COG2207	Transcriptional regulator
IN878_RS16535	COG1982	Orn Lys Arg decarboxylase major
IN878_RS16540	COG2169	Transcriptional regulator
IN878_RS16545	COG1486	melibiose metabolic process
IN878_RS16550	COG2211	Major facilitator Superfamily
IN878_RS16555	COG3647	Membrane
IN878_RS16560	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IN878_RS16560	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IN878_RS16565	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
IN878_RS16570	COG4565	transcriptional regulatory protein
IN878_RS16575	COG3290	protein histidine kinase activity
IN878_RS16580	COG3592	Divergent 4Fe-4S mono-cluster
IN878_RS16585	COG2388	GCN5-related N-acetyl-transferase
IN878_RS16600	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IN878_RS16605	COG3104	oligopeptide transport
IN878_RS16610	COG1982	Orn Lys Arg decarboxylase major
IN878_RS16615	COG0531	amino acid
IN878_RS16620	COG3710	Transcriptional regulator
IN878_RS16630	COG1309	transcriptional regulator
IN878_RS16635	COG4232	protein-disulfide reductase activity
IN878_RS16645	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
IN878_RS16650	COG1027	Aspartate ammonia-lyase
IN878_RS16655	COG3030	protein affecting phage T7 exclusion by the F plasmid
IN878_RS16660	COG0531	amino acid
IN878_RS16685	COG1509	lysine 2,3-aminomutase activity
IN878_RS16695	COG5510	response to toxic substance
IN878_RS16700	COG5510	response to toxic substance
IN878_RS16705	COG2076	Multidrug Resistance protein
IN878_RS16710	COG3040	lipid binding
IN878_RS16715	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IN878_RS16730	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IN878_RS16735	COG1053	succinate dehydrogenase
IN878_RS16745	COG0531	amino acid
IN878_RS16760	COG3264	Mechanosensitive ion channel
IN878_RS16760	COG1511	domain protein
IN878_RS16800	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IN878_RS16805	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IN878_RS16805	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IN878_RS16810	COG0802	atpase or kinase
IN878_RS16815	COG0860	N-Acetylmuramoyl-L-alanine amidase
IN878_RS16835	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IN878_RS16840	COG0330	HflC and HflK could
IN878_RS16845	COG0330	HflC and HflK could
IN878_RS16850	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
IN878_RS16865	COG0557	exoribonuclease II activity
IN878_RS16870	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IN878_RS16875	COG3789	protein conserved in bacteria
IN878_RS16880	COG1842	Phage shock protein A
IN878_RS16890	COG3766	membrane
IN878_RS16895	COG5463	Belongs to the UPF0441 family
IN878_RS16900	COG0754	glutathionylspermidine amidase activity
IN878_RS16905	COG1960	acyl-CoA dehydrogenase activity
IN878_RS16915	COG3650	response to hydrogen peroxide
IN878_RS16920	COG1073	alpha beta
IN878_RS16935	COG3037	sugar-specific permease SgaT UlaA
IN878_RS16940	COG3414	Phosphotransferase system galactitol-specific IIB component
IN878_RS16980	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IN878_RS16990	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IN878_RS17000	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IN878_RS17005	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
IN878_RS17010	COG4670	ketone body catabolic process
IN878_RS17015	COG1024	Enoyl-CoA hydratase
IN878_RS17025	COG1028	Short-chain dehydrogenase reductase Sdr
IN878_RS17030	COG1309	transcriptional regulator
IN878_RS17035	COG3061	Opacity-associated protein A
IN878_RS17040	COG0545	Peptidyl-prolyl cis-trans isomerase
IN878_RS17045	COG1113	amino acid transport
IN878_RS17055	COG0697	spore germination
IN878_RS17060	COG0702	epimerase
IN878_RS17065	COG1733	regulation of RNA biosynthetic process
IN878_RS17070	COG0737	Belongs to the 5'-nucleotidase family
IN878_RS17075	COG1218	3'(2'),5'-bisphosphate nucleotidase
IN878_RS17080	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
IN878_RS17090	COG1253	flavin adenine dinucleotide binding
IN878_RS17100	COG0729	surface antigen
IN878_RS17105	COG2911	Protein conserved in bacteria
IN878_RS17110	COG2105	PFAM AIG2 family protein
IN878_RS17115	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IN878_RS17120	COG1879	ABC-type sugar transport system periplasmic component
IN878_RS17125	COG1129	ABC transporter
IN878_RS17130	COG1172	Belongs to the binding-protein-dependent transport system permease family
IN878_RS17135	COG1172	Belongs to the binding-protein-dependent transport system permease family
IN878_RS17145	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IN878_RS17155	COG0312	modulator of DNA gyrase
IN878_RS17160	COG3783	Cytochrome b(562)
IN878_RS17165	COG0602	queuosine metabolic process
IN878_RS17170	COG1328	CTP reductase activity
IN878_RS17175	COG0366	Alpha amylase catalytic
IN878_RS17180	COG1263	PTS System
IN878_RS17180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IN878_RS17185	COG1609	Transcriptional regulator
IN878_RS17195	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IN878_RS17200	COG0251	oxidation-reduction process
IN878_RS17220	COG0251	oxidation-reduction process
IN878_RS17225	COG1028	Short-chain dehydrogenase reductase Sdr
IN878_RS17230	COG1309	transcriptional regulator
IN878_RS17235	COG2731	YhcH YjgK YiaL family protein
IN878_RS17250	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
IN878_RS17255	COG0456	acetyltransferase
IN878_RS17270	COG2927	DNA polymerase III (CHI subunit)
IN878_RS17280	COG0795	lipopolysaccharide-transporting ATPase activity
IN878_RS17285	COG0795	lipopolysaccharide-transporting ATPase activity
IN878_RS17290	COG0433	COG0433 Predicted ATPase
IN878_RS17295	COG1064	alcohol dehydrogenase
IN878_RS17365	COG2085	NADP oxidoreductase coenzyme F420-dependent
IN878_RS17370	COG1120	ATPase activity
IN878_RS17375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IN878_RS17380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IN878_RS17385	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
IN878_RS17390	COG4772	TonB-dependent receptor
IN878_RS17395	COG3712	iron ion homeostasis
IN878_RS17400	COG1595	DNA-templated transcription, initiation
IN878_RS17500	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
IN878_RS17505	COG0582	viral genome integration into host DNA
IN878_RS17510	COG4974	Belongs to the 'phage' integrase family
IN878_RS17520	COG3539	Fimbrial protein
IN878_RS17525	COG3121	Chaperone
IN878_RS17530	COG3188	usher protein
IN878_RS17535	COG3539	Fimbrial protein
IN878_RS17540	COG3539	Fimbrial protein
IN878_RS17545	COG3539	Fimbrial protein
IN878_RS17550	COG2610	gluconate transmembrane transporter activity
IN878_RS17560	COG0246	Mannitol dehydrogenase
IN878_RS17565	COG2186	Transcriptional regulator
IN878_RS17585	COG0583	DNA-binding transcription factor activity
IN878_RS17590	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IN878_RS17595	COG0700	Nucleoside recognition
IN878_RS17600	COG3366	ferrous iron transmembrane transporter activity
IN878_RS17610	COG0477	Major facilitator Superfamily
IN878_RS17625	COG1924	4 iron, 4 sulfur cluster binding
IN878_RS17630	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
IN878_RS17635	COG2733	membrane
IN878_RS17640	COG2814	Major facilitator Superfamily
IN878_RS17665	COG0523	cobalamin synthesis protein
IN878_RS17670	COG2879	small protein
IN878_RS17675	COG1966	Carbon starvation protein
IN878_RS17680	COG0840	transmembrane signaling receptor activity
IN878_RS17685	COG2271	Major facilitator Superfamily
IN878_RS17690	COG1802	Transcriptional regulator
IN878_RS17695	COG1063	alcohol dehydrogenase
IN878_RS17710	COG1484	DNA-dependent DNA replication
IN878_RS17725	COG2966	Psort location CytoplasmicMembrane, score
IN878_RS17730	COG2197	response regulator
IN878_RS17735	COG2197	response regulator
IN878_RS17740	COG4114	ferric iron reductase
IN878_RS17770	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
IN878_RS17775	COG0456	acetyltransferase
IN878_RS17780	COG1011	Hydrolase
IN878_RS17790	COG2823	Periplasmic or secreted lipoprotein
IN878_RS17800	COG4667	esterase of the alpha-beta hydrolase superfamily
IN878_RS17805	COG0084	hydrolase, TatD family'
IN878_RS17810	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IN878_RS17815	COG1328	CTP reductase activity
IN878_RS17850	COG3726	membrane protein affecting hemolysin expression
IN878_RS17855	COG0560	Phosphoserine phosphatase
IN878_RS17860	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IN878_RS17865	COG3172	ATPase kinase involved in NAD metabolism
IN878_RS17865	COG1056	cytidyltransferase-related domain
IN878_RS17875	COG0488	(ABC) transporter
IN878_RS17880	COG0741	lytic transglycosylase activity
IN878_RS17900	COG2207	Transcriptional regulator
IN878_RS17900	COG3708	Transcriptional regulator
IN878_RS17905	COG3045	CreA protein
IN878_RS17910	COG0745	RESPONSE REGULATOR receiver
IN878_RS17915	COG2205	protein histidine kinase activity
IN878_RS17920	COG4452	Inner membrane protein CreD
IN878_RS17925	COG0745	RESPONSE REGULATOR receiver
IN878_RS17935	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
IN878_RS17945	COG0527	aspartate kinase activity
IN878_RS17945	COG0460	homoserine dehydrogenase
IN878_RS17955	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IN878_RS17970	COG1115	amino acid carrier protein
IN878_RS17975	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IN878_RS17980	COG0521	Mo-molybdopterin cofactor biosynthetic process
IN878_RS17985	COG1584	GPR1 FUN34 yaaH family protein
IN878_RS17990	COG4735	regulation of single-species biofilm formation
IN878_RS18010	COG3385	transposase activity
IN878_RS18025	COG0583	DNA-binding transcription factor activity
IN878_RS18050	COG0196	riboflavin kinase activity
IN878_RS18065	COG1047	Peptidyl-prolyl cis-trans
IN878_RS18085	COG0505	Belongs to the CarA family
IN878_RS18090	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IN878_RS18140	COG0644	oxidoreductase
IN878_RS18145	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IN878_RS18150	COG2271	Major facilitator Superfamily
IN878_RS18165	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IN878_RS18190	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IN878_RS18200	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IN878_RS18205	COG0564	pseudouridine synthase activity
IN878_RS18215	COG0417	DNA replication proofreading
IN878_RS18220	COG0235	Class ii aldolase
IN878_RS18235	COG4977	sequence-specific DNA binding
IN878_RS18240	COG0586	Pfam SNARE associated Golgi protein
IN878_RS18250	COG1178	ABC-type Fe3 transport system permease component
IN878_RS18260	COG2826	transposase and inactivated derivatives, IS30 family
IN878_RS18280	COG2814	Major facilitator Superfamily
IN878_RS18295	COG0473	3-isopropylmalate dehydrogenase activity
IN878_RS18310	COG0583	DNA-binding transcription factor activity
IN878_RS18320	COG0028	Belongs to the TPP enzyme family
IN878_RS18325	COG0440	acetolactate synthase activity
IN878_RS18335	COG1609	Transcriptional regulator
IN878_RS18350	COG3116	cell division
IN878_RS18355	COG0768	penicillin binding
IN878_RS18360	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IN878_RS18365	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IN878_RS18375	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IN878_RS18380	COG0772	Belongs to the SEDS family
IN878_RS18395	COG1181	Belongs to the D-alanine--D-alanine ligase family
IN878_RS18400	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IN878_RS18405	COG0849	cell division
IN878_RS18410	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IN878_RS18430	COG0494	nUDIX hydrolase
IN878_RS18445	COG0237	dephospho-CoA kinase activity
IN878_RS18460	COG1459	type II secretion system
IN878_RS18465	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IN878_RS18470	COG4969	Belongs to the N-Me-Phe pilin family
IN878_RS18475	COG0157	Belongs to the NadC ModD family
IN878_RS18480	COG3023	N-Acetylmuramoyl-L-alanine amidase
IN878_RS18485	COG3725	Membrane protein required for beta-lactamase induction
IN878_RS18490	COG1113	amino acid transport
IN878_RS18495	COG2186	Transcriptional regulator
IN878_RS18500	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
IN878_RS18505	COG0508	dehydrogenase complex catalyzes the overall conversion of
IN878_RS18510	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IN878_RS18515	COG3064	Membrane
IN878_RS18520	COG1049	propionate catabolic process, 2-methylcitrate cycle
IN878_RS18545	COG2132	Multicopper oxidase
IN878_RS18550	COG4993	Dehydrogenase
IN878_RS18555	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
IN878_RS18560	COG0288	reversible hydration of carbon dioxide
IN878_RS18565	COG1131	(ABC) transporter
IN878_RS18570	COG0842	Transport permease protein
IN878_RS18575	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
IN878_RS18580	COG0726	polysaccharide deacetylase
IN878_RS18590	COG5464	transposase or invertase
IN878_RS18605	COG3539	Fimbrial protein
IN878_RS18610	COG3539	Fimbrial protein
IN878_RS18615	COG3539	Fimbrial protein
IN878_RS18620	COG3539	Fimbrial protein
IN878_RS18625	COG3188	usher protein
IN878_RS18630	COG3121	Chaperone
IN878_RS18635	COG3539	Fimbrial protein
IN878_RS18640	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IN878_RS18645	COG0617	tRNA 3'-terminal CCA addition
IN878_RS18655	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IN878_RS18665	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IN878_RS18670	COG1643	Atp-dependent helicase
IN878_RS18675	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IN878_RS18680	COG4774	siderophore transport
IN878_RS18685	COG1120	ATPase activity
IN878_RS18690	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IN878_RS18695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IN878_RS18720	COG2860	membrane
IN878_RS18725	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IN878_RS18740	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IN878_RS18745	COG3835	regulator
IN878_RS18755	COG1408	metallophosphoesterase
IN878_RS18770	COG0024	Methionine aminopeptidase
IN878_RS18795	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
IN878_RS18800	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IN878_RS18805	COG0575	Belongs to the CDS family
IN878_RS18810	COG0750	zinc metalloprotease
IN878_RS18820	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
IN878_RS18825	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IN878_RS18850	COG0587	DNA-directed DNA polymerase activity
IN878_RS18860	COG1982	Orn Lys Arg decarboxylase major
IN878_RS18865	COG0346	lactoylglutathione lyase activity
IN878_RS18870	COG0037	tRNA processing
IN878_RS18875	COG4568	rho-dependent transcription termination
IN878_RS18885	COG4681	YaeQ
IN878_RS18890	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IN878_RS18895	COG3015	lipoprotein NlpE involved in copper resistance
IN878_RS18900	COG0791	NLP P60 protein
IN878_RS18910	COG1720	tRNA m6t6A37 methyltransferase activity
IN878_RS18920	COG1464	Belongs to the NlpA lipoprotein family
IN878_RS18925	COG2011	ABC-type metal ion transport system permease component
IN878_RS18930	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IN878_RS18935	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IN878_RS18970	COG0656	L-ascorbic acid biosynthetic process
IN878_RS18975	COG0583	DNA-binding transcription factor activity
IN878_RS18990	COG0741	lytic transglycosylase activity
IN878_RS18990	COG1388	LysM domain
IN878_RS19000	COG2226	methyltransferase
IN878_RS19010	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IN878_RS19030	COG4104	PAAR repeat-containing protein
IN878_RS19035	COG3157	Type VI secretion system effector, Hcp
IN878_RS19060	COG5433	transposase activity
IN878_RS19065	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IN878_RS19075	COG1960	acyl-CoA dehydrogenase activity
IN878_RS19085	COG0121	glutamine amidotransferase
IN878_RS19090	COG3034	peptidoglycan biosynthetic process
IN878_RS19095	COG3041	Addiction module toxin RelE StbE family
IN878_RS19100	COG3077	Addiction module antitoxin, RelB DinJ family
IN878_RS19110	COG1943	Transposase
IN878_RS19130	COG2161	toxin-antitoxin pair type II binding
IN878_RS19140	COG0454	-acetyltransferase
IN878_RS19155	COG2195	Cleaves the N-terminal amino acid of tripeptides
IN878_RS19175	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IN878_RS19195	COG0582	viral genome integration into host DNA
IN878_RS19210	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
IN878_RS19225	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IN878_RS19230	COG4197	protein conserved in bacteria, prophage-related
IN878_RS19245	COG1846	Transcriptional regulator
IN878_RS19265	COG3436	PFAM IS66 Orf2 family protein
IN878_RS19270	COG4372	Transposase
IN878_RS19305	COG1192	Involved in chromosome partitioning
IN878_RS19315	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IN878_RS19320	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IN878_RS19325	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
IN878_RS19330	COG2080	2 iron, 2 sulfur cluster binding
IN878_RS19335	COG3477	response to acidic pH
IN878_RS19340	COG0727	PFAM Uncharacterised protein family (UPF0153)
IN878_RS19345	COG3121	Chaperone
IN878_RS19355	COG3188	usher protein
IN878_RS19400	COG2207	Transcriptional regulator
IN878_RS19400	COG3708	Transcriptional regulator
IN878_RS19410	COG3059	membrane
IN878_RS19420	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IN878_RS19425	COG2207	Transcriptional regulator
IN878_RS19430	COG0247	lactate metabolic process
IN878_RS19435	COG1139	Iron-sulfur cluster binding protein
IN878_RS19440	COG1556	Lactate utilization protein
IN878_RS19465	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IN878_RS19475	COG2200	EAL domain
IN878_RS19475	COG2771	luxR family
IN878_RS19480	COG0583	DNA-binding transcription factor activity
IN878_RS19490	COG0666	response to abiotic stimulus
IN878_RS19500	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IN878_RS19505	COG1304	FMN binding
IN878_RS19515	COG0549	Belongs to the carbamate kinase family
IN878_RS19520	COG0402	S-adenosylhomocysteine deaminase activity
IN878_RS19525	COG1064	alcohol dehydrogenase
IN878_RS19540	COG1280	lysine exporter protein (LysE YggA)
IN878_RS19550	COG3829	transcription factor binding
IN878_RS19555	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IN878_RS19560	COG0372	Belongs to the citrate synthase family
IN878_RS19565	COG2079	MmgE PrpD family protein
IN878_RS19570	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IN878_RS19575	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IN878_RS19580	COG0402	S-adenosylhomocysteine deaminase activity
IN878_RS19585	COG0583	DNA-binding transcription factor activity
IN878_RS19590	COG0288	reversible hydration of carbon dioxide
IN878_RS19600	COG2807	transmembrane transport
IN878_RS19605	COG0110	maltose O-acetyltransferase activity
IN878_RS19610	COG2223	nitrite transmembrane transporter activity
IN878_RS19615	COG3250	beta-galactosidase activity
IN878_RS19620	COG1609	Transcriptional regulator
IN878_RS19625	COG1414	Transcriptional regulator
IN878_RS19645	COG3971	2-oxopent-4-enoate hydratase activity
IN878_RS19660	COG2814	Major facilitator Superfamily
IN878_RS19665	COG3122	Protein conserved in bacteria
IN878_RS19695	COG1215	transferase activity, transferring glycosyl groups
IN878_RS19700	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IN878_RS19705	COG4521	taurine ABC transporter
IN878_RS19715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IN878_RS19720	COG2175	clavaminate synthase activity
IN878_RS19725	COG0113	porphobilinogen synthase activity
IN878_RS19730	COG3468	outer membrane autotransporter barrel domain protein
IN878_RS19735	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IN878_RS19740	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IN878_RS19745	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
IN878_RS19765	COG1181	Belongs to the D-alanine--D-alanine ligase family
IN878_RS19780	COG1785	Belongs to the alkaline phosphatase family
IN878_RS19790	COG3706	GGDEF domain
IN878_RS19795	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IN878_RS19815	COG4126	flavin adenine dinucleotide binding
IN878_RS19840	COG1940	carbohydrate kinase activity
IN878_RS19845	COG2814	Major facilitator Superfamily
IN878_RS19850	COG0419	ATPase involved in DNA repair
IN878_RS19855	COG0420	3'-5' exonuclease activity
IN878_RS19860	COG0745	RESPONSE REGULATOR receiver
IN878_RS19865	COG5002	protein histidine kinase activity
IN878_RS19870	COG1114	Component of the transport system for branched-chain amino acids
IN878_RS19875	COG1113	amino acid transport
IN878_RS19880	COG0366	Alpha amylase catalytic
IN878_RS19900	COG1862	Preprotein translocase
IN878_RS19905	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IN878_RS19910	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IN878_RS19915	COG1403	HNH endonuclease
IN878_RS19920	COG3248	Nucleoside-binding outer membrane protein
IN878_RS19925	COG4238	major outer membrane lipoprotein
IN878_RS19935	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IN878_RS19935	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IN878_RS19950	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IN878_RS19955	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IN878_RS19960	COG0667	Aldo Keto reductase
IN878_RS19970	COG0142	geranyltranstransferase activity
IN878_RS19985	COG0693	protein deglycase activity
IN878_RS19990	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IN878_RS20000	COG2814	Major facilitator Superfamily
IN878_RS20010	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IN878_RS20015	COG1845	cytochrome c oxidase, subunit III
IN878_RS20020	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IN878_RS20025	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IN878_RS20030	COG2223	nitrite transmembrane transporter activity
IN878_RS20035	COG3056	Lipoprotein
IN878_RS20040	COG0271	Belongs to the BolA IbaG family
IN878_RS20060	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IN878_RS20065	COG0776	regulation of translation
IN878_RS20070	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IN878_RS20075	COG1555	photosystem II stabilization
IN878_RS20080	COG0824	Thioesterase
IN878_RS20090	COG4533	DNA binding
IN878_RS20100	COG1522	sequence-specific DNA binding
IN878_RS20105	COG1132	(ABC) transporter
IN878_RS20110	COG1132	(ABC) transporter
IN878_RS20115	COG0347	Belongs to the P(II) protein family
IN878_RS20120	COG0004	ammonium transporteR
IN878_RS20125	COG1946	Acyl-CoA thioesterase
IN878_RS20130	COG3126	Type III secretion system lipoprotein chaperone (YscW)
IN878_RS20135	COG3695	enzyme binding
IN878_RS20145	COG5507	3-demethylubiquinone-9 3-methyltransferase
IN878_RS20160	COG0110	maltose O-acetyltransferase activity
IN878_RS20175	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IN878_RS20180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IN878_RS20185	COG1309	transcriptional regulator
IN878_RS20190	COG3264	Mechanosensitive ion channel
IN878_RS20190	COG1196	nuclear chromosome segregation
IN878_RS20200	COG3923	Primosomal replication protein n
IN878_RS20205	COG2832	Protein of unknown function (DUF454)
IN878_RS20215	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IN878_RS20250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IN878_RS20255	COG4651	solute:proton antiporter activity
IN878_RS20255	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IN878_RS20260	COG2223	nitrite transmembrane transporter activity
IN878_RS20265	COG0737	Belongs to the 5'-nucleotidase family
IN878_RS20270	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IN878_RS20275	COG3735	TraB family
IN878_RS20280	COG3093	addiction module antidote protein HigA
IN878_RS20285	COG2217	Heavy metal translocating P-type atpase
IN878_RS20290	COG2066	Belongs to the glutaminase family
IN878_RS20295	COG0531	amino acid
IN878_RS20300	COG0789	Transcriptional regulator
IN878_RS20305	COG1585	Membrane protein implicated in regulation of membrane protease activity
IN878_RS20310	COG0330	HflC and HflK could
IN878_RS20315	COG4619	ABC transporter
IN878_RS20320	COG0390	transport system, permease component
IN878_RS20325	COG3118	belongs to the thioredoxin family
IN878_RS20330	COG0300	oxidoreductase activity
IN878_RS20335	COG2755	lipolytic protein G-D-S-L family
IN878_RS20340	COG4181	ATPase activity
IN878_RS20345	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
IN878_RS20350	COG3209	COG3209 Rhs family protein
IN878_RS20360	COG3209	COG3209 Rhs family protein
IN878_RS20385	COG0583	DNA-binding transcription factor activity
IN878_RS20395	COG1414	Transcriptional regulator
IN878_RS20400	COG3960	tartronate-semialdehyde synthase activity
IN878_RS20405	COG3622	Belongs to the hyi family
IN878_RS20410	COG2084	Dehydrogenase
IN878_RS20415	COG1953	Uracil, thiamine, allantoin
IN878_RS20425	COG2233	PERMEase
IN878_RS20430	COG1929	Belongs to the glycerate kinase type-1 family
IN878_RS20435	COG3257	ureidoglycine aminohydrolase activity
IN878_RS20440	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IN878_RS20445	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
IN878_RS20450	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IN878_RS20455	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IN878_RS20465	COG0549	Belongs to the carbamate kinase family
IN878_RS20470	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IN878_RS20475	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IN878_RS20485	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IN878_RS20495	COG1988	membrane-bound metal-dependent
IN878_RS20500	COG2501	S4 domain
IN878_RS20510	COG3539	Fimbrial protein
IN878_RS20515	COG3121	Chaperone
IN878_RS20525	COG3539	Fimbrial protein
IN878_RS20530	COG3539	Fimbrial protein
IN878_RS20535	COG2197	response regulator
IN878_RS20545	COG2207	Transcriptional regulator
IN878_RS20555	COG4783	chaperone-mediated protein folding
IN878_RS20560	COG1215	transferase activity, transferring glycosyl groups
IN878_RS20565	COG5002	protein histidine kinase activity
IN878_RS20570	COG0745	RESPONSE REGULATOR receiver
IN878_RS20575	COG1538	Outer membrane efflux protein
IN878_RS20580	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IN878_RS20585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IN878_RS20590	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IN878_RS20595	COG1113	amino acid transport
IN878_RS20600	COG0668	transmembrane transport
IN878_RS20605	COG0778	Nitroreductase
IN878_RS20610	COG2315	Protein conserved in bacteria
IN878_RS20630	COG3385	transposase activity
IN878_RS20635	COG2977	Belongs to the P-Pant transferase superfamily
IN878_RS20640	COG4771	TonB-dependent receptor
IN878_RS20645	COG2382	esterase
IN878_RS20650	COG3251	PFAM MbtH domain protein
IN878_RS20670	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
IN878_RS20675	COG1120	ATPase activity
IN878_RS20680	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IN878_RS20685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IN878_RS20695	COG4592	Periplasmic binding protein
IN878_RS20700	COG1169	isochorismate synthase
IN878_RS20705	COG1021	2,3-dihydroxybenzoate-AMP ligase
IN878_RS20710	COG1535	isochorismatase
IN878_RS20710	COG3433	isochorismatase activity
IN878_RS20715	COG1028	Short-chain dehydrogenase reductase Sdr
IN878_RS20720	COG2050	protein possibly involved in aromatic compounds catabolism
IN878_RS20725	COG1966	Carbon starvation protein
IN878_RS20730	COG2879	small protein
IN878_RS20735	COG0371	Dehydrogenase
IN878_RS20740	COG0436	Aminotransferase
IN878_RS20745	COG1475	DNA binding
IN878_RS20750	COG3969	phosphoadenosine phosphosulfate
IN878_RS20755	COG0583	DNA-binding transcription factor activity
IN878_RS20760	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IN878_RS20765	COG0450	alkyl hydroperoxide reductase
IN878_RS20770	COG3634	alkyl hydroperoxide reductase activity
IN878_RS20775	COG0589	response to stress
IN878_RS20780	COG1063	alcohol dehydrogenase
IN878_RS20785	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IN878_RS20790	COG3719	Belongs to the RNase T2 family
IN878_RS20795	COG0471	metal ion transport
IN878_RS20810	COG3051	citrate lyase alpha subunit
IN878_RS20815	COG2301	Belongs to the HpcH HpaI aldolase family
IN878_RS20825	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
IN878_RS20830	COG3290	protein histidine kinase activity
IN878_RS20835	COG4565	transcriptional regulatory protein
IN878_RS20840	COG3069	C4-dicarboxylate transmembrane transporter activity
IN878_RS20865	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IN878_RS20875	COG0583	DNA-binding transcription factor activity
IN878_RS20890	COG1686	Belongs to the peptidase S11 family
IN878_RS20895	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IN878_RS20900	COG0772	Belongs to the SEDS family
IN878_RS20905	COG0768	penicillin binding
IN878_RS20915	COG0799	negative regulation of ribosome biogenesis
IN878_RS20920	COG0406	alpha-ribazole phosphatase activity
IN878_RS20930	COG1466	dna polymerase III delta subunit
IN878_RS20945	COG2888	peptidyl-tyrosine sulfation
IN878_RS20950	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
IN878_RS20960	COG2214	Heat shock protein DnaJ domain protein
IN878_RS20965	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
IN878_RS20975	COG2214	Heat shock protein DnaJ domain protein
IN878_RS20980	COG0443	Heat shock 70 kDa protein
IN878_RS20990	COG1126	abc transporter atp-binding protein
IN878_RS20995	COG0765	amino acid transport
IN878_RS21000	COG0765	amino acid transport
IN878_RS21005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IN878_RS21010	COG0815	Transfers the fatty acyl group on membrane lipoproteins
IN878_RS21015	COG4535	Mg2 and Co2 transporter CorC
IN878_RS21025	COG1702	phosphate starvation-inducible protein PhoH
IN878_RS21035	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IN878_RS21075	COG0367	asparagine synthase
IN878_RS21080	COG0647	UMP catabolic process
IN878_RS21085	COG1846	Transcriptional regulator
IN878_RS21085	COG1940	carbohydrate kinase activity
IN878_RS21090	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IN878_RS21100	COG2190	(PTS) system
IN878_RS21100	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IN878_RS21100	COG1263	PTS System
IN878_RS21120	COG0735	belongs to the Fur family
IN878_RS21130	COG0716	FMN binding
IN878_RS21140	COG0596	Alpha beta hydrolase
IN878_RS21145	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
IN878_RS21150	COG0033	Phosphoglucomutase
IN878_RS21170	COG0531	amino acid
IN878_RS21175	COG1982	Orn Lys Arg decarboxylase major
IN878_RS21185	COG0745	RESPONSE REGULATOR receiver
IN878_RS21190	COG2205	protein histidine kinase activity
IN878_RS21220	COG3209	COG3209 Rhs family protein
IN878_RS21240	COG3272	Protein of unknown function (DUF1722)
IN878_RS21245	COG0415	Belongs to the DNA photolyase family
IN878_RS21250	COG3104	oligopeptide transport
IN878_RS21255	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IN878_RS21260	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
IN878_RS21265	COG1984	allophanate hydrolase subunit 2
IN878_RS21280	COG3180	Ammonia monooxygenase
IN878_RS21285	COG3539	Fimbrial protein
IN878_RS21290	COG3121	Chaperone
IN878_RS21295	COG3188	usher protein
IN878_RS21300	COG3539	Fimbrial protein
IN878_RS21305	COG0372	Belongs to the citrate synthase family
IN878_RS21315	COG2009	succinate dehydrogenase
IN878_RS21320	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IN878_RS21325	COG1053	succinate dehydrogenase
IN878_RS21330	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IN878_RS21335	COG0567	Dehydrogenase, E1 component
IN878_RS21340	COG0508	dehydrogenase complex catalyzes the overall conversion of
IN878_RS21350	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IN878_RS21355	COG2188	Transcriptional regulator
IN878_RS21360	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IN878_RS21360	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IN878_RS21360	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IN878_RS21365	COG0383	alpha-mannosidase activity
IN878_RS21370	COG1271	oxidase subunit
IN878_RS21375	COG1294	oxidase, subunit
IN878_RS21380	COG4890	Cyd operon protein YbgT
IN878_RS21385	COG3790	cyd operon protein YbgE
IN878_RS21390	COG0824	Thioesterase
IN878_RS21395	COG0811	peptide transport
IN878_RS21400	COG0848	biopolymer transport protein
IN878_RS21405	COG3064	Membrane
IN878_RS21415	COG2885	chlorophyll binding
IN878_RS21420	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
IN878_RS21470	COG3201	nicotinamide mononucleotide transporter
IN878_RS21475	COG1230	cation diffusion facilitator family transporter
IN878_RS21485	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IN878_RS21495	COG2017	converts alpha-aldose to the beta-anomer
IN878_RS21505	COG1085	galactose-1-phosphate uridylyltransferase
IN878_RS21510	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IN878_RS21515	COG1119	ATPase activity
IN878_RS21520	COG2005	Transcriptional regulator
IN878_RS21520	COG3585	molybdate ion transport
IN878_RS21530	COG0725	ABC transporter, periplasmic molybdate-binding protein
IN878_RS21535	COG4149	molybdate abc transporter
IN878_RS21540	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IN878_RS21545	COG0561	phosphatase activity
IN878_RS21555	COG0583	DNA-binding transcription factor activity
IN878_RS21560	COG2828	Protein conserved in bacteria
IN878_RS21565	COG0471	metal ion transport
IN878_RS21570	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IN878_RS21575	COG4677	pectinesterase activity
IN878_RS21580	COG0582	viral genome integration into host DNA
IN878_RS21685	COG3772	lysozyme
IN878_RS21730	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
IN878_RS21740	COG2207	Transcriptional regulator
IN878_RS21755	COG1881	PFAM PEBP family protein
IN878_RS21760	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IN878_RS21775	COG2226	methyltransferase
IN878_RS21780	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IN878_RS21790	COG0391	Required for morphogenesis under gluconeogenic growth conditions
IN878_RS21800	COG0521	Mo-molybdopterin cofactor biosynthetic process
IN878_RS21810	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IN878_RS21815	COG0314	molybdopterin synthase activity
IN878_RS21820	COG0670	Belongs to the BI1 family
IN878_RS21825	COG0670	Belongs to the BI1 family
IN878_RS21830	COG0392	lysyltransferase activity
IN878_RS21835	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IN878_RS21840	COG3568	Endonuclease Exonuclease Phosphatase
IN878_RS21850	COG0842	Transport permease protein
IN878_RS21855	COG0842	Transport permease protein
IN878_RS21860	COG1131	(ABC) transporter
IN878_RS21870	COG1309	transcriptional regulator
IN878_RS21875	COG0513	Belongs to the DEAD box helicase family
IN878_RS21880	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
IN878_RS21885	COG1199	ATP-dependent helicase activity
IN878_RS21890	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IN878_RS21895	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
IN878_RS21905	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IN878_RS21915	COG4774	siderophore transport
IN878_RS21930	COG0668	transmembrane transport
IN878_RS21935	COG1126	abc transporter atp-binding protein
IN878_RS21940	COG0765	amino acid transport
IN878_RS21945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IN878_RS21955	COG5006	permease, DMT superfamily
IN878_RS21965	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IN878_RS21970	COG2194	sulfuric ester hydrolase activity
IN878_RS21980	COG1321	iron dependent repressor
IN878_RS21985	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IN878_RS21990	COG1376	ErfK ybiS ycfS ynhG family protein
IN878_RS21995	COG0488	(ABC) transporter
IN878_RS22005	COG0561	phosphatase activity
IN878_RS22010	COG1882	Formate acetyltransferase
IN878_RS22015	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IN878_RS22020	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IN878_RS22025	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IN878_RS22030	COG0303	'Molybdopterin
IN878_RS22035	COG1446	asparaginase
IN878_RS22040	COG4172	Belongs to the ABC transporter superfamily
IN878_RS22045	COG0747	negative chemotaxis
IN878_RS22055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IN878_RS22060	COG2200	EAL domain
IN878_RS22065	COG2199	diguanylate cyclase activity
IN878_RS22080	COG2133	pyrroloquinoline quinone binding
IN878_RS22085	COG0625	glutathione transferase activity
IN878_RS22090	COG1686	Belongs to the peptidase S11 family
IN878_RS22095	COG1349	DNA-binding transcription factor activity
IN878_RS22100	COG0671	phosphoesterase, PA-phosphatase related
IN878_RS22105	COG2814	Major facilitator Superfamily
IN878_RS22115	COG0561	phosphatase activity
IN878_RS22120	COG0738	Major facilitator superfamily
IN878_RS22125	COG3226	Transcriptional regulator
IN878_RS22140	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IN878_RS22150	COG0778	Nitroreductase
IN878_RS22165	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IN878_RS22170	COG3842	ATPase activity
IN878_RS22175	COG1176	ABC-type spermidine putrescine transport system, permease component I
IN878_RS22180	COG1177	transmembrane transport
IN878_RS22195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IN878_RS22200	COG4160	amino acid transport
IN878_RS22205	COG4215	(ABC) transporter
IN878_RS22210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IN878_RS22215	COG1126	abc transporter atp-binding protein
IN878_RS22230	COG3023	N-Acetylmuramoyl-L-alanine amidase
IN878_RS22235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IN878_RS22240	COG0702	epimerase
IN878_RS22245	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
IN878_RS22250	COG0028	Belongs to the TPP enzyme family
IN878_RS22255	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IN878_RS22265	COG2431	L-lysine efflux transmembrane transporter activity
IN878_RS22275	COG3593	DNA synthesis involved in DNA repair
IN878_RS22280	COG2990	Protein conserved in bacteria
IN878_RS22285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IN878_RS22290	COG1136	(ABC) transporter
IN878_RS22290	COG0577	efflux transmembrane transporter activity
IN878_RS22295	COG1278	Cold shock
IN878_RS22305	COG0542	response to heat
IN878_RS22325	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IN878_RS22330	COG4988	ABC transporter
IN878_RS22335	COG0492	ferredoxin-NADP+ reductase activity
IN878_RS22340	COG1522	sequence-specific DNA binding
IN878_RS22345	COG1674	ftsk spoiiie
IN878_RS22345	COG1178	ABC-type Fe3 transport system permease component
IN878_RS22355	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IN878_RS22365	COG0243	molybdopterin cofactor binding
IN878_RS22370	COG0437	4 iron, 4 sulfur cluster binding
IN878_RS22375	COG3302	dmso reductase anchor subunit
IN878_RS22380	COG1335	isochorismatase
IN878_RS22390	COG0531	amino acid
IN878_RS22395	COG0583	DNA-binding transcription factor activity
IN878_RS22400	COG2249	NAD(P)H dehydrogenase (quinone) activity
IN878_RS22405	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IN878_RS22410	COG4974	Belongs to the 'phage' integrase family
IN878_RS22480	COG4695	Portal protein
IN878_RS22570	COG5301	cellulose 1,4-beta-cellobiosidase activity
IN878_RS22635	COG1882	Formate acetyltransferase
IN878_RS22640	COG2116	formate transmembrane transporter activity
IN878_RS22645	COG1944	ATP diphosphatase activity
IN878_RS22650	COG2323	membrane
IN878_RS22665	COG0501	Belongs to the peptidase M48B family
IN878_RS22675	COG0539	negative regulation of cytoplasmic translation
IN878_RS22685	COG2333	competence protein COMEC
IN878_RS22685	COG0658	competence protein
IN878_RS22690	COG1132	(ABC) transporter
IN878_RS22695	COG1663	tetraacyldisaccharide 4'-kinase activity
IN878_RS22700	COG3214	Protein conserved in bacteria
IN878_RS22715	COG3173	Aminoglycoside phosphotransferase
IN878_RS22720	COG1434	Gram-negative-bacterium-type cell wall biogenesis
IN878_RS22725	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IN878_RS22735	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
IN878_RS22745	COG2989	Protein conserved in bacteria
IN878_RS22750	COG3108	Peptidase M15
IN878_RS22755	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IN878_RS22760	COG1448	Aminotransferase
IN878_RS22780	COG0308	aminopeptidase N
IN878_RS22785	COG1116	anion transmembrane transporter activity
IN878_RS22790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IN878_RS22800	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IN878_RS22805	COG0431	NADPH-dependent FMN reductase
IN878_RS22810	COG3539	Fimbrial protein
IN878_RS22815	COG3121	Chaperone
IN878_RS22820	COG3188	usher protein
IN878_RS22825	COG3539	Fimbrial protein
IN878_RS22830	COG3539	Fimbrial protein
IN878_RS22835	COG3539	Fimbrial protein
IN878_RS22840	COG3121	Chaperone
IN878_RS22855	COG0633	Ferredoxin
IN878_RS22855	COG3217	Mosc domain protein beta barrel domain protein
IN878_RS22865	COG0488	(ABC) transporter
IN878_RS22870	COG2995	paraquat-inducible protein a
IN878_RS22875	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IN878_RS22875	COG3008	intermembrane lipid transfer
IN878_RS22880	COG3009	Protein conserved in bacteria
IN878_RS22885	COG3130	regulation of translation
IN878_RS22895	COG1067	ATP-dependent peptidase activity
IN878_RS22905	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IN878_RS22905	COG2885	chlorophyll binding
IN878_RS22915	COG3070	regulator of competence-specific genes
IN878_RS22920	COG1289	transmembrane transporter activity
IN878_RS22925	COG3304	Inner membrane component domain
IN878_RS22930	COG0210	DNA helicase
IN878_RS22945	COG1832	CoA-binding protein
IN878_RS22960	COG1254	Belongs to the acylphosphatase family
IN878_RS22965	COG2920	part of a sulfur-relay system
IN878_RS22970	COG0670	Belongs to the BI1 family
IN878_RS22980	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
IN878_RS22985	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
IN878_RS22990	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
IN878_RS22995	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IN878_RS23000	COG1999	signal sequence binding
IN878_RS23005	COG1773	rubredoxin
IN878_RS23010	COG1271	oxidase subunit
IN878_RS23015	COG1294	oxidase, subunit
IN878_RS23030	COG0489	protein tyrosine kinase activity
IN878_RS23030	COG3206	protein involved in exopolysaccharide biosynthesis
IN878_RS23035	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IN878_RS23040	COG1596	polysaccharide export
IN878_RS23045	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IN878_RS23065	COG1278	Cold shock
IN878_RS23070	COG1278	Cold shock
IN878_RS23090	COG0348	domain, Protein
IN878_RS23095	COG0784	Response regulator, receiver
IN878_RS23095	COG2205	protein histidine kinase activity
IN878_RS23095	COG2198	Histidine kinase
IN878_RS23100	COG1879	ABC-type sugar transport system periplasmic component
IN878_RS23105	COG0745	RESPONSE REGULATOR receiver
IN878_RS23110	COG3005	denitrification pathway
IN878_RS23115	COG0243	molybdopterin cofactor binding
IN878_RS23120	COG3381	protein complex oligomerization
IN878_RS23155	COG3729	General stress protein
IN878_RS23160	COG2233	PERMEase
IN878_RS23195	COG1309	transcriptional regulator
IN878_RS23200	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IN878_RS23200	COG0506	proline dehydrogenase activity
IN878_RS23200	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IN878_RS23210	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IN878_RS23225	COG2822	iron ion transport
IN878_RS23230	COG2837	iron assimilation
IN878_RS23235	COG1702	phosphate starvation-inducible protein PhoH
IN878_RS23240	COG3658	cytochrome
IN878_RS23245	COG1215	transferase activity, transferring glycosyl groups
IN878_RS23250	COG1649	PFAM Uncharacterised BCR, COG1649
IN878_RS23250	COG0726	polysaccharide deacetylase
IN878_RS23255	COG0457	Tetratricopeptide repeat
IN878_RS23260	COG3706	GGDEF domain
IN878_RS23280	COG0582	viral genome integration into host DNA
IN878_RS23315	COG1401	restriction endodeoxyribonuclease activity
IN878_RS23330	COG3706	GGDEF domain
IN878_RS23335	COG0457	Tetratricopeptide repeat
IN878_RS23340	COG0726	polysaccharide deacetylase
IN878_RS23340	COG1649	PFAM Uncharacterised BCR, COG1649
IN878_RS23345	COG1215	transferase activity, transferring glycosyl groups
IN878_RS23350	COG3658	cytochrome
IN878_RS23355	COG1702	phosphate starvation-inducible protein PhoH
IN878_RS23430	COG1620	l-lactate permease
IN878_RS23435	COG0277	FAD linked oxidase domain protein
IN878_RS23440	COG0247	lactate metabolic process
IN878_RS23445	COG1139	Iron-sulfur cluster binding protein
IN878_RS23450	COG1556	Lactate utilization protein
IN878_RS23460	COG3039	Transposase
IN878_RS23625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IN878_RS23635	COG3436	PFAM IS66 Orf2 family protein
IN878_RS23740	COG5001	Diguanylate cyclase
IN878_RS23740	COG3300	MHYT domain
IN878_RS23765	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IN878_RS23820	COG0697	spore germination
IN878_RS23895	COG4221	oxidoreductase activity
IN878_RS23955	COG1192	Involved in chromosome partitioning
IN878_RS23990	COG2026	Addiction module toxin, RelE StbE family
IN878_RS24125	COG5301	cellulose 1,4-beta-cellobiosidase activity
IN878_RS24140	COG5301	cellulose 1,4-beta-cellobiosidase activity
IN878_RS24140	COG5301	cellulose 1,4-beta-cellobiosidase activity
IN878_RS24140	COG5301	cellulose 1,4-beta-cellobiosidase activity
IN878_RS24190	COG3133	Outer membrane lipoprotein
IN878_RS24290	COG0338	D12 class N6 adenine-specific DNA methyltransferase
IN878_RS24320	COG0305	Participates in initiation and elongation during chromosome replication
IN878_RS24550	COG2132	Multicopper oxidase
IN878_RS24600	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IN878_RS24620	COG0489	protein tyrosine kinase activity
IN878_RS24755	COG3504	Conjugal transfer protein
IN878_RS24905	COG3436	PFAM IS66 Orf2 family protein
IN878_RS24950	COG2801	Transposase and inactivated derivatives
IN878_RS25000	COG2801	Transposase and inactivated derivatives
IN878_RS25085	COG2801	Transposase and inactivated derivatives
IN878_RS25095	COG3436	PFAM IS66 Orf2 family protein
IN878_RS25145	COG2826	transposase and inactivated derivatives, IS30 family
IN878_RS25160	COG3468	outer membrane autotransporter barrel domain protein
IN878_RS25195	COG4372	Transposase
IN878_RS25200	COG3436	PFAM IS66 Orf2 family protein
IN878_RS25225	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
IN878_RS25390	COG1475	DNA binding